MONDO|Ensembl=ENSMODG00000011062.3|UniProtKB=F7EMB7 F7EMB7 CCK PTHR10786:SF0 CHOLECYSTOKININ CHOLECYSTOKININ signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;neuropeptide hormone activity#GO:0005184 multicellular organismal process#GO:0032501;digestion#GO:0007586 extracellular region#GO:0005576;neuron projection#GO:0043005;axon#GO:0030424;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 CCKR signaling map#P06959>CCK-G#P07062;CCKR signaling map#P06959>CCK-GRR#P07131;CCKR signaling map#P06959>CCK#P07077;CCKR signaling map#P06959>CCK-33#P07045;CCKR signaling map#P06959>CCK-22#P07022;CCKR signaling map#P06959>Pro CCK @ TGN#P07174;CCKR signaling map#P06959>CCK-83#P07118;CCKR signaling map#P06959>CCK-8#P07226;CCKR signaling map#P06959>Signal-pre-pro CCK#P07223;CCKR signaling map#P06959>Pre-pro CCK @ ER#P07128;CCKR signaling map#P06959>Pro-CCK @ secretory granule#P07206;CCKR signaling map#P06959>CCK-58#P07164 MONDO|Ensembl=ENSMODG00000024611.2|UniProtKB=F7D0R0 F7D0R0 PTHR11913:SF15 COFILIN-RELATED COFILIN-2 actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin cytoskeleton organization#GO:0030036;protein depolymerization#GO:0051261;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;actin filament depolymerization#GO:0030042;cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Cofilin#P00508 MONDO|Ensembl=ENSMODG00000019248.4|UniProtKB=F6QTF6 F6QTF6 SLC46A1 PTHR23507:SF2 ZGC:174356 PROTON-COUPLED FOLATE TRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000005005.4|UniProtKB=A0A5F8H555 A0A5F8H555 BAZ2B PTHR45915:SF1 TRANSCRIPTION INTERMEDIARY FACTOR BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000049853.1|UniProtKB=A0A5F8GA20 A0A5F8GA20 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008585.4|UniProtKB=A0A5F8HJS9 A0A5F8HJS9 ATL2 PTHR10751:SF42 GUANYLATE BINDING PROTEIN ATLASTIN-2 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;organelle organization#GO:0006996 G-protein#PC00020;heterotrimeric G-protein#PC00117 MONDO|Ensembl=ENSMODG00000050365.1|UniProtKB=F7EUI4 F7EUI4 PTHR26453:SF76 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13H1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007895.3|UniProtKB=A0A5F8HDC9 A0A5F8HDC9 PTHR48071:SF15 SRCR DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR FAMILY 12 SUBFAMILY J MEMBER 2 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000005382.4|UniProtKB=A0A5F8GXV2 A0A5F8GXV2 SBNO2 PTHR12706:SF5 STRAWBERRY NOTCH-RELATED PROTEIN STRAWBERRY NOTCH HOMOLOG 2 DNA binding#GO:0003677;protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;chromatin DNA binding#GO:0031490;nucleic acid binding#GO:0003676;binding#GO:0005488 leukocyte activation#GO:0045321;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of inflammatory response#GO:0050727;cell activation#GO:0001775;hemopoiesis#GO:0030097;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;macrophage activation#GO:0042116;developmental process#GO:0032502;regulation of response to stress#GO:0080134;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;leukocyte differentiation#GO:0002521;cell activation involved in immune response#GO:0002263;response to peptide#GO:1901652;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;myeloid leukocyte activation#GO:0002274;response to cytokine#GO:0034097;response to chemical#GO:0042221;negative regulation of macromolecule biosynthetic process#GO:0010558;immune effector process#GO:0002252;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;osteoclast differentiation#GO:0030316;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of defense response#GO:0031347;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;cell development#GO:0048468;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;myeloid cell differentiation#GO:0030099;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;immune system process#GO:0002376;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;leukocyte activation involved in immune response#GO:0002366;negative regulation of RNA metabolic process#GO:0051253 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000014204.4|UniProtKB=F6TQY6 F6TQY6 TBX2 PTHR11267:SF82 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX2 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 MONDO|Ensembl=ENSMODG00000015644.4|UniProtKB=F7F157 F7F157 SLC25A46 PTHR21252:SF2 TB1 PROTEIN-RELATED MITOCHONDRIAL OUTER MEMBRANE PROTEIN SLC25A46 organelle fission#GO:0048285;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;mitochondrial fission#GO:0000266;multicellular organismal process#GO:0032501;mitochondrion organization#GO:0007005;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;neuron projection development#GO:0031175;organelle organization#GO:0006996;axon development#GO:0061564;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 MONDO|Ensembl=ENSMODG00000009887.4|UniProtKB=F6VCZ1 F6VCZ1 CASP7 PTHR10454:SF31 CASPASE CASPASE-7 cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;execution phase of apoptosis#GO:0097194;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;positive regulation of neuron apoptotic process#GO:0043525;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 protease#PC00190;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>Caspase 7#P00300;FAS signaling pathway#P00020>Pro-Caspase7#P00605;FAS signaling pathway#P00020>Caspase7#P00595 MONDO|Ensembl=ENSMODG00000008691.4|UniProtKB=A0A5F8GNL1 A0A5F8GNL1 FBXO16 PTHR46857:SF2 EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 ONCOGENE-LIKE F-BOX ONLY PROTEIN 16 MONDO|Ensembl=ENSMODG00000044666.1|UniProtKB=F7AXI2 F7AXI2 LOC100028946 PTHR48002:SF17 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4N5 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008606.4|UniProtKB=F6PHB8 F6PHB8 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000017703.4|UniProtKB=F6Y5Z1 F6Y5Z1 AKIRIN1 PTHR13293:SF9 AKIRIN-RELATED AKIRIN-1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of response to biotic stimulus#GO:0002831;regulation of developmental process#GO:0050793;regulation of leukocyte migration#GO:0002685;regulation of granulocyte chemotaxis#GO:0071622;regulation of cell projection assembly#GO:0060491;positive regulation of chemotaxis#GO:0050921;regulation of DNA-templated transcription#GO:0006355;regulation of cell motility#GO:2000145;positive regulation of biosynthetic process#GO:0009891;positive regulation of innate immune response#GO:0045089;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;cell migration#GO:0016477;developmental process#GO:0032502;regulation of response to stress#GO:0080134;regulation of gene expression#GO:0010468;positive regulation of cell motility#GO:2000147;positive regulation of cellular component organization#GO:0051130;positive regulation of metabolic process#GO:0009893;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of response to external stimulus#GO:0032103;positive regulation of RNA metabolic process#GO:0051254;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;regulation of defense response#GO:0031347;positive regulation of cell projection organization#GO:0031346;regulation of immune response#GO:0050776;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;negative regulation of cell population proliferation#GO:0008285;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;positive regulation of immune response#GO:0050778;regulation of cell migration#GO:0030334;positive regulation of defense response#GO:0031349;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of locomotion#GO:0040017;regulation of biosynthetic process#GO:0009889;developmental growth#GO:0048589;regulation of innate immune response#GO:0045088;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of chemotaxis#GO:0050920;regulation of cellular component biogenesis#GO:0044087;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular component organization#GO:0051128;tissue regeneration#GO:0042246;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regeneration#GO:0031099;positive regulation of cellular component biogenesis#GO:0044089;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;growth#GO:0040007;positive regulation of cell differentiation#GO:0045597 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000000498.4|UniProtKB=F6TUB3 F6TUB3 LOC100012925 PTHR42874:SF1 URICASE URICASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;nucleobase catabolic process#GO:0046113;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;purine-containing compound catabolic process#GO:0072523;purine nucleobase catabolic process#GO:0006145 microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000009759.4|UniProtKB=F6WT52 F6WT52 CSF1R PTHR24416:SF47 TYROSINE-PROTEIN KINASE RECEPTOR MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;transferase activity#GO:0016740;kinase activity#GO:0016301;signaling receptor activity#GO:0038023;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199 signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;positive regulation of cell motility#GO:2000147;leukocyte differentiation#GO:0002521;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;regulation of cell communication#GO:0010646;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;osteoclast differentiation#GO:0030316;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;biological regulation#GO:0065007;hemopoiesis#GO:0030097;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;cell migration#GO:0016477;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of locomotion#GO:0040017;cellular developmental process#GO:0048869;regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038004.1|UniProtKB=A0A5F8GEE0 A0A5F8GEE0 PTHR28664:SF3 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791 cell junction protein#PC00070;tight junction#PC00214 MONDO|Ensembl=ENSMODG00000019237.3|UniProtKB=F6RDJ5 F6RDJ5 POLDIP2 PTHR14289:SF16 F-BOX ONLY PROTEIN 3 POLYMERASE DELTA-INTERACTING PROTEIN 2 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;translesion synthesis#GO:0019985;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA synthesis involved in DNA replication#GO:0090592 membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoid#GO:0009295;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrial nucleoid#GO:0042645;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000042132.1|UniProtKB=A0A5F8GSL0 A0A5F8GSL0 monDomV1R1213 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003104.4|UniProtKB=F6PI38 F6PI38 SEPTIN10 PTHR18884:SF50 SEPTIN SEPTIN-10 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 cell cycle process#GO:0022402;cell division#GO:0051301;cellular process#GO:0009987;macromolecule localization#GO:0033036;cell cycle#GO:0007049;cytokinesis#GO:0000910;intracellular protein localization#GO:0008104;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179 cell periphery#GO:0071944;cell cortex#GO:0005938;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085 MONDO|Gene=SNRPB|UniProtKB=Q9TU66 Q9TU66 SNRPB PTHR10701:SF15 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEINS B AND B' binding#GO:0005488;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021 RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;U2-type prespliceosome#GO:0071004;U2 snRNP#GO:0005686;catalytic step 2 spliceosome#GO:0071013;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;U4/U6 x U5 tri-snRNP complex#GO:0046540;cytoplasm#GO:0005737 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000013186.4|UniProtKB=F7FAD9 F7FAD9 NECTIN1 PTHR23277:SF69 NECTIN-RELATED NECTIN-1 virus receptor activity#GO:0001618;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488 heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;macromolecule localization#GO:0033036;homophilic cell-cell adhesion#GO:0007156;cell adhesion#GO:0007155;protein localization to cell junction#GO:1902414;intracellular protein localization#GO:0008104;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell junction#GO:0030054;apical junction complex#GO:0043296 cell adhesion molecule#PC00069 Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha#P00160;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha N-terminal fragment#P00164;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha C-terminal fragment#P00177;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha transmembrane fragment#P00134;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha intracellular fragment#P00159 MONDO|Ensembl=ENSMODG00000029783.2|UniProtKB=K7E0P4 K7E0P4 PTHR19446:SF479 REVERSE TRANSCRIPTASES RNA-DIRECTED DNA POLYMERASE reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000037704.1|UniProtKB=A0A5F8GZ51 A0A5F8GZ51 PTHR10553:SF2 SMALL NUCLEAR RIBONUCLEOPROTEIN SMALL NUCLEAR RIBONUCLEOPROTEIN G binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 U12-type spliceosomal complex#GO:0005689;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;U1 snRNP#GO:0005685;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;precatalytic spliceosome#GO:0071011;catalytic complex#GO:1902494;spliceosomal tri-snRNP complex#GO:0097526;cytoplasmic ribonucleoprotein granule#GO:0036464;U2-type prespliceosome#GO:0071004;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;U5 snRNP#GO:0005682;P granule#GO:0043186;U2 snRNP#GO:0005686;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;small nuclear ribonucleoprotein complex#GO:0030532;SMN-Sm protein complex#GO:0034719;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000013885.4|UniProtKB=F6VT30 F6VT30 CLIP2 PTHR18916:SF10 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cytoskeleton organization#GO:0007010;cytoplasmic microtubule organization#GO:0031122;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;microtubule-based process#GO:0007017;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;microtubule end#GO:1990752;cell cortex#GO:0005938;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000006214.3|UniProtKB=A0A5F8GT97 A0A5F8GT97 ERGIC1 PTHR10984:SF36 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 1 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000003062.4|UniProtKB=A0A5F8GW57 A0A5F8GW57 ABLIM2 PTHR24213:SF6 ACTIN-BINDING LIM PROTEIN ACTIN-BINDING LIM PROTEIN 2 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;lamellipodium assembly#GO:0030032;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000024956.1|UniProtKB=F6UCJ4 F6UCJ4 PTHR31022:SF4 CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 regulation of mitotic spindle assembly#GO:1901673;regulation of organelle assembly#GO:1902115;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of microtubule-based process#GO:0032886;regulation of spindle assembly#GO:0090169;regulation of mitotic spindle organization#GO:0060236;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of spindle organization#GO:0090224;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726 axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929;axon#GO:0030424;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;spindle#GO:0005819;microtubule organizing center#GO:0005815;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005 MONDO|Ensembl=ENSMODG00000009891.4|UniProtKB=F6VCD4 F6VCD4 PPARGC1B PTHR15528:SF12 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-BETA transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organismal-level homeostasis#GO:0048871;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000048319.1|UniProtKB=A0A5F8H996 A0A5F8H996 TMEM26 PTHR22168:SF3 TMEM26 PROTEIN TRANSMEMBRANE PROTEIN 26 MONDO|Ensembl=ENSMODG00000005339.4|UniProtKB=F7CHT4 F7CHT4 THOC3 PTHR22839:SF0 THO COMPLEX SUBUNIT 3 THO3 THO COMPLEX SUBUNIT 3 nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;biosynthetic process#GO:0009058;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705 nucleus#GO:0005634;THO complex#GO:0000347;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transcription export complex#GO:0000346;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000029454.2|UniProtKB=K7DZ22 K7DZ22 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000020449.4|UniProtKB=F7AQF1 F7AQF1 ST8SIA3 PTHR11987:SF36 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-N-ACETYLNEURAMINATE ALPHA-2,8-SIALYLTRANSFERASE ST8SIA3 catalytic activity#GO:0003824;transferase activity#GO:0016740;sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757 oligosaccharide metabolic process#GO:0009311;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000024780.2|UniProtKB=F7C6V8 F7C6V8 DEXI PTHR17070:SF0 DEXAMETHASONE-INDUCED PROTEIN DEXAMETHASONE-INDUCED PROTEIN MONDO|Ensembl=ENSMODG00000014167.4|UniProtKB=A0A5F8GRA7 A0A5F8GRA7 THSD7A PTHR11311:SF8 SPONDIN THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 7A actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000023836.1|UniProtKB=F6U8X0 F6U8X0 PTHR26453:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024008.2|UniProtKB=F6V3Z4 F6V3Z4 PTHR24056:SF334 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;histone modifying activity#GO:0140993;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;mitotic G2/M transition checkpoint#GO:0044818;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;intracellular signal transduction#GO:0035556;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;G2/M transition of mitotic cell cycle#GO:0000086;cell cycle phase transition#GO:0044770;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;signal transduction#GO:0007165;cell cycle G2/M phase transition#GO:0044839;cellular process#GO:0009987;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cell cycle process#GO:0022402 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway#P00059>Cdc2#P04634 MONDO|Ensembl=ENSMODG00000020640.4|UniProtKB=F7EME9 F7EME9 OCIAD1 PTHR13336:SF4 OVARIAN CARCINOMA IMMUNOREACTIVE ANTIGEN OCIA DOMAIN-CONTAINING PROTEIN 1 intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000004969.4|UniProtKB=F7FL62 F7FL62 HTR5A PTHR24248:SF209 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 5A ISOFORM X1 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000010342.4|UniProtKB=F6S918 F6S918 FOXO1 PTHR45767:SF1 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O1 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;cellular response to chemical stimulus#GO:0070887;positive regulation of metabolic process#GO:0009893;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to insulin stimulus#GO:0032869;regulation of carbohydrate metabolic process#GO:0006109;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;cellular response to peptide hormone stimulus#GO:0071375;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246 CCKR signaling map#P06959>FOXO1#P07167;PI3 kinase pathway#P00048>FOXO#P01198;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>FKHR#P00898 MONDO|Ensembl=ENSMODG00000020693.4|UniProtKB=K7DZI9 K7DZI9 PPAT PTHR11907:SF0 AMIDOPHOSPHORIBOSYLTRANSFERASE AMIDOPHOSPHORIBOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;transferase#PC00220 De novo purine biosynthesis#P02738>Amidophosphoribosyl transferase#P02905 MONDO|Ensembl=ENSMODG00000002635.4|UniProtKB=A0A5F8GLF3 A0A5F8GLF3 ARHGEF10L PTHR12877:SF16 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 10-LIKE PROTEIN enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of actin filament-based process#GO:0032970;positive regulation of actin filament bundle assembly#GO:0032233;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;biological regulation#GO:0065007;SREBP signaling pathway#GO:0032933;actin filament-based process#GO:0030029;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of supramolecular fiber organization#GO:1902903;cellular response to stimulus#GO:0051716;regulation of stress fiber assembly#GO:0051492;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular component biogenesis#GO:0044089;cellular response to stress#GO:0033554;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of actin filament bundle assembly#GO:0032231;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000043337.1|UniProtKB=A0A5F8GLY8 A0A5F8GLY8 LOC100011249 PTHR24242:SF248 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 9A2 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000008910.3|UniProtKB=A0A5F8HC80 A0A5F8HC80 RBM44 PTHR48026:SF8 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN RNA-BINDING PROTEIN 44 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000028791.2|UniProtKB=K7E491 K7E491 PTHR13602:SF2 UPF0488 PROTEIN C8ORF33 UPF0488 PROTEIN C8ORF33 MONDO|Ensembl=ENSMODG00000048368.1|UniProtKB=A0A5F8G4Q4 A0A5F8G4Q4 PTHR22574:SF6 FAMILY NOT NAMED GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 2 MONDO|Ensembl=ENSMODG00000005980.4|UniProtKB=F6SLF5 F6SLF5 OR4E2 PTHR26451:SF160 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 4E2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000047763.1|UniProtKB=A0A5F8GKE7 A0A5F8GKE7 PTHR11434:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT ND4L NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4L transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000002259.5|UniProtKB=F7CW65 F7CW65 TRIP10 PTHR15735:SF17 FCH AND DOUBLE SH3 DOMAINS PROTEIN CDC42-INTERACTING PROTEIN 4 regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;regulation of actin cytoskeleton organization#GO:0032956;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of organelle organization#GO:0033043;cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009;regulation of actin filament-based process#GO:0032970 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000000598.4|UniProtKB=F6TBE6 F6TBE6 APBA3 PTHR12345:SF9 SYNTENIN RELATED AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 3 binding#GO:0005488;peptide binding#GO:0042277 chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;regulation of biological process#GO:0050789;cellular process#GO:0009987;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 cell junction#GO:0030054;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;dendritic tree#GO:0097447;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794;dendritic spine#GO:0043197 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093;Alzheimer disease-amyloid secretase pathway#P00003>X11alpha#P00084 MONDO|Ensembl=ENSMODG00000014481.4|UniProtKB=F7FKW4 F7FKW4 SLC1A6 PTHR11958:SF67 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 4 dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;solute:monoatomic cation symporter activity#GO:0015294;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;acidic amino acid transmembrane transporter activity#GO:0015172;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;L-glutamate import#GO:0051938;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;dicarboxylic acid transport#GO:0006835;L-glutamate transmembrane transport#GO:0015813;amino acid transport#GO:0006865;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036;Ionotropic glutamate receptor pathway#P00037>EAAT#P01011 MONDO|Ensembl=ENSMODG00000040020.1|UniProtKB=A0A5F8GX40 A0A5F8GX40 TMEM272 PTHR33444:SF7 SI:DKEY-19B23.12-RELATED TRANSMEMBRANE PROTEIN 272 MONDO|Ensembl=ENSMODG00000014565.3|UniProtKB=F7DQ88 F7DQ88 PTHR45859:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA TRANSLATION INITIATION FACTOR EIF2B SUBUNIT BETA translation factor activity#GO:0180051;guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000014317.4|UniProtKB=F6W3Y2 F6W3Y2 PTHR12844:SF12 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS TESTIS EXPRESSED GENE 16 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004055.3|UniProtKB=F7C393 F7C393 PGK1 PTHR11406:SF0 PHOSPHOGLYCERATE KINASE PHOSPHOGLYCERATE KINASE kinase activity#GO:0016301;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;phosphoglycerate kinase activity#GO:0004618;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine nucleotide catabolic process#GO:0006195;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;hexose biosynthetic process#GO:0019319;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide catabolic process#GO:0009166;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;ribonucleoside diphosphate metabolic process#GO:0009185;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;ATP metabolic process#GO:0046034;gluconeogenesis#GO:0006094;nicotinamide nucleotide metabolic process#GO:0046496;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;nucleoside phosphate catabolic process#GO:1901292;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine nucleoside triphosphate metabolic process#GO:0009144;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;pyruvate metabolic process#GO:0006090;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ADP catabolic process#GO:0046032;carbohydrate biosynthetic process#GO:0016051;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphoglycerate kinase#P00671 MONDO|Ensembl=ENSMODG00000005213.4|UniProtKB=F7A201 F7A201 ZC4H2 PTHR31058:SF2 ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of neuron differentiation#GO:0045664;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;multicellular organism development#GO:0007275;positive regulation of cell differentiation#GO:0045597;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000018845.4|UniProtKB=A0A5F8GVB1 A0A5F8GVB1 TMOD4 PTHR10901:SF9 TROPOMODULIN TROPOMODULIN-4 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;actin filament-based process#GO:0030029;multicellular organismal process#GO:0032501;cellular developmental process#GO:0048869;system process#GO:0003008;actin filament organization#GO:0007015;muscle contraction#GO:0006936;developmental process#GO:0032502;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989 actin cytoskeleton#GO:0015629;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000044289.1|UniProtKB=A0A5F8GRF4 A0A5F8GRF4 PTHR24099:SF7 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED CARDIOMYOPATHY-ASSOCIATED PROTEIN 5 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000016591.4|UniProtKB=F6ZCW7 F6ZCW7 ITPR2 PTHR13715:SF53 RYANODINE RECEPTOR AND IP3 RECEPTOR INOSITOL 1,4,5-TRISPHOSPHATE-GATED CALCIUM CHANNEL ITPR2 ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;ligand-gated monoatomic ion channel activity#GO:0015276;cation binding#GO:0043169;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;phosphatidylinositol binding#GO:0035091;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;binding#GO:0005488;calcium ion binding#GO:0005509;gated channel activity#GO:0022836;metal ion binding#GO:0046872;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873 calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;signal transduction#GO:0007165;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;monoatomic ion transport#GO:0006811;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;metal ion transport#GO:0030001;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;calcium ion transmembrane transport#GO:0070588 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;cell periphery#GO:0071944;sarcoplasmic reticulum#GO:0016529;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;sarcoplasm#GO:0016528;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;vesicle#GO:0031982 ligand-gated ion channel#PC00141;ion channel#PC00133 Wnt signaling pathway#P00057>IP3 Gated Calcium Channel#P01426;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>IP3R#P05932;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>IP3R#P01064;Endothelin signaling pathway#P00019>IP3 R#P00590;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IP3R#P00842;Histamine H1 receptor mediated signaling pathway#P04385>IP3R#P04486;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>IP3 channel#P00735;Gonadotropin-releasing hormone receptor pathway#P06664>IP3R#P06768;PDGF signaling pathway#P00047>IP3 receptor#P01160;B cell activation#P00010>IP3R#P00398 MONDO|Ensembl=ENSMODG00000007372.4|UniProtKB=A0A5F8GYY1 A0A5F8GYY1 TBCD PTHR12658:SF1 BETA-TUBULIN COFACTOR D TUBULIN-SPECIFIC CHAPERONE D molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;binding#GO:0005488;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;enzyme activator activity#GO:0008047 microtubule-based process#GO:0007017;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;metabolic process#GO:0008152;cytoskeleton organization#GO:0007010;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule cytoskeleton organization#GO:0000226;protein metabolic process#GO:0019538;protein folding#GO:0006457;cell junction organization#GO:0034330;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000011179.3|UniProtKB=F6ZZ79 F6ZZ79 LPAR6 PTHR24232:SF3 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 6 bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019017.4|UniProtKB=A0A5F8G2Q8 A0A5F8G2Q8 TNKS PTHR24180:SF3 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED POLY [ADP-RIBOSE] POLYMERASE TANKYRASE-1 glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763 positive regulation of canonical Wnt signaling pathway#GO:0090263;intracellular protein localization#GO:0008104;regulation of telomere maintenance#GO:0032204;regulation of chromosome organization#GO:0033044;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;protein localization to organelle#GO:0033365;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;positive regulation of DNA metabolic process#GO:0051054;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of macromolecule metabolic process#GO:0010604;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;regulation of Wnt signaling pathway#GO:0030111;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 kinase modulator#PC00140;kinase inhibitor#PC00139 MONDO|Gene=LDHB|UniProtKB=Q9XT86 Q9XT86 LDHB PTHR43128:SF2 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE B CHAIN catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000015480.3|UniProtKB=F6WWA7 F6WWA7 WNT16 PTHR12027:SF70 WNT RELATED PROTEIN WNT-16 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell fate commitment#GO:0045165;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 MONDO|Ensembl=ENSMODG00000050729.1|UniProtKB=A0A5F8GVE3 A0A5F8GVE3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000004840.4|UniProtKB=F6U5H7 F6U5H7 ERCC4 PTHR10150:SF0 DNA REPAIR ENDONUCLEASE XPF DNA REPAIR ENDONUCLEASE XPF DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;damaged DNA binding#GO:0003684 macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA repair#GO:0006281;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;resolution of meiotic recombination intermediates#GO:0000712;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;mitotic recombination#GO:0006312;sexual reproduction#GO:0019953;reproductive process#GO:0022414;homologous recombination#GO:0035825;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;nucleotide-excision repair#GO:0006289;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;response to stimulus#GO:0050896;cellular component organization#GO:0016043;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nucleotide-excision repair complex#GO:0000109;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;endodeoxyribonuclease#PC00093 MONDO|Ensembl=ENSMODG00000006433.4|UniProtKB=F7EZ73 F7EZ73 NPHP4 PTHR31043:SF3 NEPHROCYSTIN-4 NEPHROCYSTIN-4 macromolecule localization#GO:0033036;regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;intracellular protein localization#GO:0008104;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;protein localization to cilium#GO:0061512;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;localization#GO:0051179 ciliary transition zone#GO:0035869;intracellular organelle#GO:0043229;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary base#GO:0097546;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000050925.1|UniProtKB=F6PJD0 F6PJD0 PTHR13058:SF24 THREE PRIME REPAIR EXONUCLEASE 1, 2 THREE PRIME REPAIR EXONUCLEASE 2 exonuclease activity#GO:0004527;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;hydrolase activity#GO:0016787;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097 macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA catabolic process#GO:0006308;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound catabolic process#GO:0034655 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000003492.4|UniProtKB=F7CS40 F7CS40 PLEKHM2 PTHR46556:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 organelle localization#GO:0051640;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;lysosome localization#GO:0032418;Golgi organization#GO:0007030;regulation of biological process#GO:0050789;endomembrane system organization#GO:0010256;biological regulation#GO:0065007 endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000011013.3|UniProtKB=F7A0H8 F7A0H8 LOC100616797 PTHR24376:SF85 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 600-RELATED negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000009821.4|UniProtKB=F6RX61 F6RX61 CCDC186 PTHR18911:SF5 CTCL TUMOR ANTIGEN HD-CL-01 COILED-COIL DOMAIN-CONTAINING PROTEIN 186 MONDO|Ensembl=ENSMODG00000018511.4|UniProtKB=F7AGW1 F7AGW1 CEP63 PTHR18875:SF7 SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO CENTROSOMAL PROTEIN OF 63 KDA anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;centriole replication#GO:0007099;cell differentiation#GO:0030154;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular developmental process#GO:0048869;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;microtubule organizing center organization#GO:0031023;chromosome segregation#GO:0007059;developmental process#GO:0032502;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987 cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spindle pole#GO:0000922;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000024442.2|UniProtKB=F7CZR2 F7CZR2 LRATD2 PTHR46341:SF2 PROTEIN FAM84B-RELATED PROTEIN LRATD2 MONDO|Ensembl=ENSMODG00000000226.4|UniProtKB=F6SZ07 F6SZ07 CTNNBL1 PTHR14978:SF0 BETA-CATENIN-LIKE PROTEIN 1 NUCLEAR ASSOCIATED PROTEIN BETA-CATENIN-LIKE PROTEIN 1 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 MONDO|Ensembl=ENSMODG00000006403.4|UniProtKB=F7FRD3 F7FRD3 TMEM248 PTHR16002:SF5 TRANSMEMBRANE PROTEIN 248-LIKE TRANSMEMBRANE PROTEIN 248 MONDO|Ensembl=ENSMODG00000038831.1|UniProtKB=A0A5F8H8A8 A0A5F8H8A8 RNF6 PTHR45931:SF2 SI:CH211-59O9.10 E3 UBIQUITIN-PROTEIN LIGASE RNF6 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;protein ubiquitination#GO:0016567;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000003278.4|UniProtKB=F7EG27 F7EG27 COL11A1 PTHR24023:SF42 COLLAGEN ALPHA COLLAGEN ALPHA-1(XI) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000000545.4|UniProtKB=F6XM40 F6XM40 ELF3 PTHR11849:SF13 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-3 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 MONDO|Ensembl=ENSMODG00000048163.1|UniProtKB=F6PJY6 F6PJY6 LOC100009862 PTHR26453:SF108 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013131.4|UniProtKB=F7B049 F7B049 PTHR22847:SF751 WD40 REPEAT PROTEIN WD REPEAT DOMAIN 5B chromatin-protein adaptor activity#GO:0140463;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566 gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;transcription initiation-coupled chromatin remodeling#GO:0045815;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA-templated transcription initiation#GO:0006352;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;nucleic acid biosynthetic process#GO:0141187;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;transcription by RNA polymerase II#GO:0006366;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;NSL complex#GO:0044545;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000009915.4|UniProtKB=F6R9L2 F6R9L2 SLC5A1 PTHR11819:SF151 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 carbohydrate transport#GO:0008643;transport#GO:0006810;renal absorption#GO:0070293;localization#GO:0051179;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;system process#GO:0003008;D-glucose transmembrane transport#GO:1904659;renal system process#GO:0003014;cellular process#GO:0009987;import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000044330.1|UniProtKB=A0A5F8H187 A0A5F8H187 PTHR24390:SF290 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 184 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000004483.4|UniProtKB=F6VRE2 F6VRE2 SLC34A1 PTHR10010:SF21 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2A secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;phosphate transmembrane transporter activity#GO:0005315;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370 inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;transport#GO:0006810;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;localization#GO:0051179;phosphate ion transport#GO:0006817;homeostatic process#GO:0042592 cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;apical part of cell#GO:0045177;plasma membrane#GO:0005886;organelle#GO:0043226;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;cell periphery#GO:0071944;brush border#GO:0005903;apical plasma membrane#GO:0016324;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000017736.4|UniProtKB=F6Y5S7 F6Y5S7 INPP5B PTHR11200:SF307 INOSITOL 5-PHOSPHATASE TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 neuron projection#GO:0043005;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000000472.3|UniProtKB=F6UAS0 F6UAS0 HOXA6 PTHR45659:SF14 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-A6 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000010202.4|UniProtKB=F6SBL8 F6SBL8 FREM2 PTHR45739:SF4 MATRIX PROTEIN, PUTATIVE-RELATED FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 2 cellular process#GO:0009987;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;homeostatic process#GO:0042592;epithelial structure maintenance#GO:0010669;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;multicellular organismal-level homeostasis#GO:0048871;tissue homeostasis#GO:0001894 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 MONDO|Ensembl=ENSMODG00000011934.4|UniProtKB=F7DEP1 F7DEP1 UBA2 PTHR10953:SF5 UBIQUITIN-ACTIVATING ENZYME E1 SUMO-ACTIVATING ENZYME SUBUNIT 2 ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a protein#GO:0140096;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 MONDO|Ensembl=ENSMODG00000017436.4|UniProtKB=F6ZUM0 F6ZUM0 MAP3K5 PTHR11584:SF332 SERINE/THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;neuron apoptotic process#GO:0051402;cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;signaling#GO:0023052;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress#GO:0070059;regulation of cellular process#GO:0050794;apoptotic signaling pathway#GO:0097190;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;p38MAPK cascade#GO:0038066;JNK cascade#GO:0007254 non-receptor serine/threonine protein kinase#PC00167 p38 MAPK pathway#P05918>ASK1#P06043;Integrin signalling pathway#P00034>ERK#P00907;EGF receptor signaling pathway#P00018>MEKK1-5#P00553;Apoptosis signaling pathway#P00006>ASK1#P00272;FGF signaling pathway#P00021>MEKK1-5#P00634;FAS signaling pathway#P00020>ASK1#P00614;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834 MONDO|Ensembl=ENSMODG00000017968.4|UniProtKB=F7BVF7 F7BVF7 MICAL1 PTHR23167:SF35 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED [F-ACTIN]-MONOOXYGENASE MICAL1 protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;oxidoreductase activity#GO:0016491;cytoskeletal protein binding#GO:0008092;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;actin cytoskeleton organization#GO:0030036;actin filament depolymerization#GO:0030042;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;organelle organization#GO:0006996;cellular component organization#GO:0016043 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000008211.3|UniProtKB=F6ZYM0 F6ZYM0 PTHR12577:SF7 DACHSHUND DACHSHUND HOMOLOG 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000000624.3|UniProtKB=F6TAP7 F6TAP7 SDHA PTHR11632:SF51 SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT SUCCINATE DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN SUBUNIT, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 anaerobic respiration#GO:0009061;electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;generation of precursor metabolites and energy#GO:0006091 respiratory chain complex II (succinate dehydrogenase)#GO:0045273;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cell periphery#GO:0071944;respiratory chain complex#GO:0098803;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000004813.4|UniProtKB=F6V5G6 F6V5G6 SLC12A9 PTHR11827:SF98 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 9 symporter activity#GO:0015293;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;chloride transmembrane transporter activity#GO:0015108;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transport#GO:0006810 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000037212.1|UniProtKB=A0A5F8GNM6 A0A5F8GNM6 PTHR12471:SF3 VACUOLAR ATP SYNTHASE SUBUNIT S1 V-TYPE PROTON ATPASE SUBUNIT S1-LIKE PROTEIN biological regulation#GO:0065007;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080 membrane protein complex#GO:0098796;membrane#GO:0016020;cation-transporting ATPase complex#GO:0090533;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;ATPase complex#GO:1904949;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;proton-transporting V-type ATPase complex#GO:0033176;ATPase dependent transmembrane transport complex#GO:0098533 primary active transporter#PC00068;ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000011704.4|UniProtKB=F7G3Q6 F7G3Q6 MRPL1 PTHR36427:SF5 54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL1M RNA binding#GO:0003723;structural molecule activity#GO:0005198;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000015027.4|UniProtKB=F7BXD2 F7BXD2 DXO PTHR12395:SF9 DOM-3 RELATED DECAPPING AND EXORIBONUCLEASE PROTEIN phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA decapping#GO:0110154;RNA catabolic process#GO:0006401;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000004462.4|UniProtKB=F6R6K1 F6R6K1 LOC100018507 PTHR45805:SF7 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR ROR-BETA-LIKE sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000016731.4|UniProtKB=F6S064 F6S064 NEFL PTHR45652:SF8 GLIAL FIBRILLARY ACIDIC PROTEIN NEUROFILAMENT LIGHT POLYPEPTIDE structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;intermediate filament bundle assembly#GO:0045110;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;cellular component assembly#GO:0022607;intermediate filament cytoskeleton organization#GO:0045104;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;axon#GO:0030424;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;neuron projection#GO:0043005;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell junction#GO:0030054;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000011433.4|UniProtKB=F6RJP1 F6RJP1 IK PTHR12765:SF5 RED PROTEIN IK FACTOR CYTOKINE IK PROTEIN RED RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 cytokine#PC00083 MONDO|Ensembl=ENSMODG00000039580.1|UniProtKB=A0A5F8H2X8 A0A5F8H2X8 SPX PTHR28590:SF1 SPEXIN SPEXIN receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;neuropeptide hormone activity#GO:0005184;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of muscle system process#GO:0090257;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of muscle contraction#GO:0006937;regulation of system process#GO:0044057;regulation of smooth muscle contraction#GO:0006940 extracellular region#GO:0005576;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000003356.5|UniProtKB=F6ZPV3 F6ZPV3 KCTD3 PTHR15859:SF2 SETA BINDING PROTEIN 1 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD3 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018543.4|UniProtKB=F7GD23 F7GD23 MTO1 PTHR11806:SF4 GLUCOSE INHIBITED DIVISION PROTEIN A 5-TAURINOMETHYLURIDINE-[TRNA] SYNTHASE SUBUNIT MTO1, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mitochondrial RNA modification#GO:1900864;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;mitochondrial RNA metabolic process#GO:0000959;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000021160.3|UniProtKB=A0A5F8GRN2 A0A5F8GRN2 LOC100032315 PTHR15141:SF75 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 ELONGIN-A RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA-templated transcription elongation#GO:0006354;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000010461.4|UniProtKB=F7F7L5 F7F7L5 CYC1 PTHR10266:SF3 CYTOCHROME C1 CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679 electron transport chain#GO:0022900;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Huntington disease#P00029>Cytochrome c#P00785;FAS signaling pathway#P00020>CytochromeC#P00620;ATP synthesis#P02721>Cyt bc1#P02799 MONDO|Ensembl=ENSMODG00000020464.2|UniProtKB=F7FJH1 F7FJH1 PTHR24215:SF3 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 2 cytoskeletal protein binding#GO:0008092;binding#GO:0005488;structural molecule activity#GO:0005198;protein binding#GO:0005515 muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;tissue development#GO:0009888;developmental process#GO:0032502;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;nucleus#GO:0005634;Z disc#GO:0030018;sarcomere#GO:0030017;membraneless organelle#GO:0043228;I band#GO:0031674;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;myofibril#GO:0030016;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000013584.4|UniProtKB=F7AVY5 F7AVY5 TIMM50 PTHR12210:SF3 DULLARD PROTEIN PHOSPHATASE MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM50 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein localization to mitochondrion#GO:0070585;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365 mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000015353.3|UniProtKB=F6WXN2 F6WXN2 PLGRKT PTHR13411:SF7 PLASMINOGEN RECEPTOR (KT) PLASMINOGEN RECEPTOR (KT) regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of proteolysis#GO:0030162;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628 MONDO|Ensembl=ENSMODG00000004255.4|UniProtKB=F6TW49 F6TW49 TBX22 PTHR11267:SF116 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX22 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cell fate specification#GO:0001708;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 MONDO|Ensembl=ENSMODG00000044142.1|UniProtKB=A0A5F8G358 A0A5F8G358 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000010260.2|UniProtKB=F6VQ45 F6VQ45 LOC100030236 PTHR26451:SF920 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000019628.4|UniProtKB=F6XPW1 F6XPW1 SHISAL2B PTHR31395:SF2 SHISA PROTEIN SHISA-LIKE-2B scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000047686.1|UniProtKB=A0A5F8G780 A0A5F8G780 RAP2A PTHR24070:SF221 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-2A hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;intracellular signaling cassette#GO:0141124;negative regulation of locomotion#GO:0040013;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;small GTPase-mediated signal transduction#GO:0007264;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of cell migration#GO:0030334;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906 MONDO|Ensembl=ENSMODG00000015462.4|UniProtKB=F6S3J4 F6S3J4 BIRC6 PTHR46116:SF39 (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME DUAL E2 UBIQUITIN-CONJUGATING ENZYME_E3 UBIQUITIN-PROTEIN LIGASE BIRC6 transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000000256.5|UniProtKB=H9H8A3 H9H8A3 CHPF PTHR12369:SF22 CHONDROITIN SYNTHASE CHONDROITIN POLYMERIZING FACTOR, NON-CATALYTIC SUBUNIT hexosyltransferase activity#GO:0016758;protein complex scaffold activity#GO:0140378;transferase activity#GO:0016740;catalytic activity#GO:0003824;structural molecule activity#GO:0005198;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000001333.4|UniProtKB=F7FWD1 F7FWD1 DPH6 PTHR12196:SF2 DOMAIN OF UNKNOWN FUNCTION 71 DUF71 -CONTAINING PROTEIN DIPHTHINE--AMMONIA LIGASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;metabolic process#GO:0008152;protein modification process#GO:0036211;primary metabolic process#GO:0044238 MONDO|Ensembl=ENSMODG00000021068.4|UniProtKB=F6V1X5 F6V1X5 IL10RB PTHR20859:SF50 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-10 RECEPTOR SUBUNIT BETA cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cytokine receptor#P00866;Interleukin signaling pathway#P00036>Receptor subunit beta#P00974 MONDO|Ensembl=ENSMODG00000019577.4|UniProtKB=F6QN25 F6QN25 HAPLN3 PTHR22804:SF40 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 3 multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;skeletal system development#GO:0001501;system development#GO:0048731 cell junction#GO:0030054;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;external encapsulating structure#GO:0030312;membrane#GO:0016020;extracellular matrix#GO:0031012;cell periphery#GO:0071944 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 MONDO|Ensembl=ENSMODG00000048588.1|UniProtKB=A0A5F8G4L8 A0A5F8G4L8 PTHR23248:SF38 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303 lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;plasma membrane organization#GO:0007009;cellular component organization#GO:0016043;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;organophosphate ester transport#GO:0015748;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule localization#GO:0033036;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;lipid transport#GO:0006869 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000011779.4|UniProtKB=A0A5F8H503 A0A5F8H503 CCNG2 PTHR10177:SF60 CYCLINS CYCLIN-G2 enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843 protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000045883.1|UniProtKB=A0A5F8GFG8 A0A5F8GFG8 LOC100025021 PTHR46167:SF1 N-LYSINE METHYLTRANSFERASE KMT5A N-LYSINE METHYLTRANSFERASE KMT5A histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;chromosome organization#GO:0051276;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000042738.1|UniProtKB=A0A5F8HFE0 A0A5F8HFE0 PTHR47633:SF4 IMMUNOGLOBULIN IG-LIKE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000006609.4|UniProtKB=F6ZWR9 F6ZWR9 CLDN7 PTHR12002:SF78 CLAUDIN CLAUDIN-7 cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216 anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;apical junction complex#GO:0043296;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000050330.1|UniProtKB=A0A5F8GD98 A0A5F8GD98 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000014179.3|UniProtKB=F6U790 F6U790 PTHR46735:SF3 CALPAIN, SMALL SUBUNIT 1 A-RELATED CALPAIN SMALL SUBUNIT 1A-RELATED endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;caspase complex#GO:0008303;peptidase complex#GO:1905368 MONDO|Ensembl=ENSMODG00000024298.2|UniProtKB=F7EIE1 F7EIE1 PTHR48018:SF106 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M11 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020075.4|UniProtKB=A0A5F8GN44 A0A5F8GN44 CAST PTHR10077:SF0 CALPASTATIN CALPASTATIN peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000043422.1|UniProtKB=A0A5F8H1H3 A0A5F8H1H3 LOC100617470 PTHR26450:SF70 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR OLFR593 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021440.4|UniProtKB=F7BT97 F7BT97 APCDD1 PTHR31021:SF2 ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1 PROTEIN APCDD1 Wnt-protein binding#GO:0017147;protein binding#GO:0005515;binding#GO:0005488 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of Wnt signaling pathway#GO:0030178;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cell communication#GO:0010648 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000016644.4|UniProtKB=F7GGT7 F7GGT7 LUC7L PTHR12375:SF31 RNA-BINDING PROTEIN LUC7-RELATED RNA-BINDING PROTEIN LUC7-LIKE 1-RELATED mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site recognition#GO:0006376;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;U2-type prespliceosome#GO:0071004;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000002270.4|UniProtKB=A0A5F8GI96 A0A5F8GI96 UNC79 PTHR21696:SF2 PROTEIN UNC-79 HOMOLOG PROTEIN UNC-79 HOMOLOG MONDO|Ensembl=ENSMODG00000028511.1|UniProtKB=K7E1N6 K7E1N6 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000017030.4|UniProtKB=F6YJ09 F6YJ09 GABRR3 PTHR18945:SF196 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT RHO-3 monoatomic anion channel activity#GO:0005253;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;chloride channel activity#GO:0005254;neurotransmitter receptor activity#GO:0030594;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215 anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;trans-synaptic signaling#GO:0099537;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization#GO:0051234;chloride transport#GO:0006821;transport#GO:0006810 signaling receptor complex#GO:0043235;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;GABA-ergic synapse#GO:0098982 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000017254.4|UniProtKB=F6TK41 F6TK41 LTV1 PTHR21531:SF0 LOW-TEMPERATURE VIABILITY PROTEIN LTV1-RELATED PROTEIN LTV1 HOMOLOG nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;ribosome localization#GO:0033750;ribosome biogenesis#GO:0042254;organelle localization#GO:0051640;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;ribosomal small subunit biogenesis#GO:0042274;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000002770.4|UniProtKB=F6YGR0 F6YGR0 SDHB PTHR11921:SF47 SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900 membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000027679.2|UniProtKB=K7E4Y7 K7E4Y7 LOC103102651 PTHR11803:SF54 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA RIBONUCLEASE UK114-LIKE catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239 RNA metabolic process#GO:0016070;negative regulation of translation#GO:0017148;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of protein metabolic process#GO:0051246;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739 deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000008571.4|UniProtKB=F7CX54 F7CX54 CA8 PTHR18952:SF104 CARBONIC ANHYDRASE CARBONIC ANHYDRASE-RELATED PROTEIN positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;positive regulation of calcium-mediated signaling#GO:0050850;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000010011.2|UniProtKB=F6UAU2 F6UAU2 PTHR24393:SF187 ZINC FINGER PROTEIN ZINC FINGER PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000001414.3|UniProtKB=F7BCY1 F7BCY1 RTCB PTHR11118:SF1 RNA-SPLICING LIGASE RTCB HOMOLOG RNA-SPLICING LIGASE RTCB ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098 RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000012115.3|UniProtKB=F7FU88 F7FU88 ETF1 PTHR10113:SF10 PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;translation factor activity#GO:0180051 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;protein-containing complex disassembly#GO:0032984;translational termination#GO:0006415;translation#GO:0006412;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 translation release factor#PC00225;translation factor#PC00223 MONDO|Ensembl=ENSMODG00000002499.4|UniProtKB=A0A5F8GAE0 A0A5F8GAE0 ANXA10 PTHR10502:SF100 ANNEXIN ANNEXIN A10 lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;phospholipid binding#GO:0005543;binding#GO:0005488 vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000039919.1|UniProtKB=A0A5F8GAF6 A0A5F8GAF6 PTHR11009:SF31 DER1-LIKE PROTEIN, DERLIN RHOMBOID DOMAIN-CONTAINING PROTEIN 2 macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;cellular process#GO:0009987;signal transduction#GO:0007165;protein metabolic process#GO:0019538;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000019297.3|UniProtKB=F6RZ66 F6RZ66 RPL23A PTHR11620:SF106 60S RIBOSOMAL PROTEIN L23A LARGE RIBOSOMAL SUBUNIT PROTEIN UL23 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000003816.4|UniProtKB=F6YW66 F6YW66 LOC100026095 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of immune response#GO:0050776 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000020073.3|UniProtKB=F7GIH2 F7GIH2 LOC100025055 PTHR48018:SF90 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AK3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001586.4|UniProtKB=F6QMS0 F6QMS0 NDFIP2 PTHR13396:SF4 NEDD4 FAMILY INTERACTING PROTEIN 1/2 NEDD4 FAMILY-INTERACTING PROTEIN 2 regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;primary metabolic process#GO:0044238;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of protein modification process#GO:0031399;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of protein ubiquitination#GO:0031396;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000017176.4|UniProtKB=F6XYN7 F6XYN7 CTPS2 PTHR11550:SF2 CTP SYNTHASE CTP SYNTHASE 2 binding#GO:0005488;catalytic activity#GO:0003824;ligase activity#GO:0016874;protein binding#GO:0005515;identical protein binding#GO:0042802;ligase activity, forming carbon-nitrogen bonds#GO:0016879 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;pyrimidine nucleobase metabolic process#GO:0006206;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ligase#PC00142;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>CTP synthase#P02931 MONDO|Ensembl=ENSMODG00000000219.4|UniProtKB=A0A5F8GF03 A0A5F8GF03 PIK3C3 PTHR10048:SF7 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity#GO:0016740;catalytic activity#GO:0003824;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 pexophagy#GO:0000425;establishment of localization#GO:0051234;glycerophospholipid biosynthetic process#GO:0046474;transport#GO:0006810;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;biological regulation#GO:0065007;macroautophagy#GO:0016236;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cell communication#GO:0007154;localization#GO:0051179;organophosphate biosynthetic process#GO:0090407;vacuole organization#GO:0007033;intracellular signal transduction#GO:0035556;organelle assembly#GO:0070925;catabolic process#GO:0009056;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;cellular component assembly#GO:0022607;glycerophospholipid metabolic process#GO:0006650;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagy#GO:0006914;signal transduction#GO:0007165;autophagosome organization#GO:1905037;cellular process#GO:0009987;process utilizing autophagic mechanism#GO:0061919;phosphatidylinositol phosphate biosynthetic process#GO:0046854;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;endocytosis#GO:0006897;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 microbody#GO:0042579;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;extrinsic component of membrane#GO:0019898;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;phosphatidylinositol 3-kinase complex, class III#GO:0035032;endosome#GO:0005768;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 kinase#PC00137 p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Angiogenesis#P00005>PI3K#P00236;PDGF signaling pathway#P00047>PI3K#P01168;Ras Pathway#P04393>PI3K#P04567;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;EGF receptor signaling pathway#P00018>PI3K#P00557;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;T cell activation#P00053>PI3K#P01322;VEGF signaling pathway#P00056>PI3K#P01413;Integrin signalling pathway#P00034>PI3K#P00936 MONDO|Ensembl=ENSMODG00000036625.1|UniProtKB=A0A5F8GVQ2 A0A5F8GVQ2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000013359.4|UniProtKB=A0A5F8H0W0 A0A5F8H0W0 GNAO1 PTHR10218:SF363 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(O) SUBUNIT ALPHA protein binding#GO:0005515;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hormone receptor binding#GO:0051427;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;G protein-coupled receptor binding#GO:0001664;pyrophosphatase activity#GO:0016462;neuropeptide receptor binding#GO:0071855;catalytic activity#GO:0003824 G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;biological regulation#GO:0065007;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698 cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165 G-protein#PC00020;heterotrimeric G-protein#PC00117 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;GABA-B receptor II signaling#P05731>Gi/oalpha#P05757;Enkephalin release#P05913>G-Protein (i)#P05974;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Opioid prodynorphin pathway#P05916>G-protein#P06002;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Endogenous cannabinoid signaling#P05730>Galpha#P05751;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Goalpha#P00729 MONDO|Ensembl=ENSMODG00000007357.4|UniProtKB=F7ADR9 F7ADR9 EDEM3 PTHR45679:SF2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 3 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;macromolecule metabolic process#GO:0043170;carbohydrate derivative metabolic process#GO:1901135;endoplasmic reticulum unfolded protein response#GO:0030968;biological regulation#GO:0065007;protein catabolic process#GO:0030163;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;response to unfolded protein#GO:0006986;regulation of biological process#GO:0050789;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;glycoprotein metabolic process#GO:0009100;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000040358.1|UniProtKB=K7E574 K7E574 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000008160.2|UniProtKB=F7EL30 F7EL30 ACTN3 PTHR11915:SF432 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-3 actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;cellular component organization#GO:0016043;muscle cell development#GO:0055001;cell development#GO:0048468;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154 myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;sarcomere#GO:0030017;cell junction#GO:0030054;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;I band#GO:0031674;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;membrane#GO:0016020;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;cell periphery#GO:0071944 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 MONDO|Ensembl=ENSMODG00000039511.1|UniProtKB=A0A5F8GQF5 A0A5F8GQF5 PTHR23226:SF466 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 235 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000012702.3|UniProtKB=A0A5F8H5Y2 A0A5F8H5Y2 PTHR10462:SF55 GLYCOSYLTRANSFERASE-RELATED HISTO-BLOOD GROUP ABO SYSTEM TRANSFERASE 1 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096 vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000015022.4|UniProtKB=F7BXF8 F7BXF8 XAB2 PTHR11246:SF5 PRE-MRNA SPLICING FACTOR PRE-MRNA-SPLICING FACTOR SYF1 nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933 catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;post-mRNA release spliceosomal complex#GO:0071014;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000025617.3|UniProtKB=F6QB74 F6QB74 TMEM267 PTHR13628:SF1 TRANSMEMBRANE PROTEIN 267 TRANSMEMBRANE PROTEIN 267 MONDO|Ensembl=ENSMODG00000006852.4|UniProtKB=A0A5F8G5T8 A0A5F8G5T8 ACAP1 PTHR23180:SF197 CENTAURIN/ARF ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000009264.3|UniProtKB=F7DAM5 F7DAM5 OR51T1 PTHR26450:SF6 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51T1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027392.2|UniProtKB=A0A5F8GP14 A0A5F8GP14 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 immune system process#GO:0002376;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;immune response#GO:0006955;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000007799.3|UniProtKB=F7A894 F7A894 PRDX4 PTHR10681:SF180 THIOREDOXIN PEROXIDASE PEROXIREDOXIN-4 catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;response to oxidative stress#GO:0006979;cellular process#GO:0009987;response to stress#GO:0006950;homeostatic process#GO:0042592;hydrogen peroxide metabolic process#GO:0042743;catabolic process#GO:0009056;response to stimulus#GO:0050896 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 peroxidase#PC00180;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000003668.3|UniProtKB=F7ABT9 F7ABT9 PTHR21021:SF16 GAF/PUTATIVE CYTOSKELETAL PROTEIN TIP41-LIKE PROTEIN protein phosphatase regulator activity#GO:0019888;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;phosphatase activator activity#GO:0019211;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;enzyme activator activity#GO:0008047 TOR signaling#GO:0031929;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000020131.4|UniProtKB=A0A5F8H6J0 A0A5F8H6J0 ARB2A PTHR21357:SF3 FAM172 FAMILY PROTEIN HOMOLOG CG10038 COTRANSCRIPTIONAL REGULATOR ARB2A RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulatory ncRNA-mediated heterochromatin formation#GO:0031048;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of gene expression#GO:0010468;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component assembly#GO:0022607;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000003708.4|UniProtKB=F7FA41 F7FA41 PTHR11073:SF11 CALRETICULIN AND CALNEXIN CALNEXIN ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein folding#GO:0006457;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000046578.1|UniProtKB=A0A5F8HD90 A0A5F8HD90 LOC100020964 PTHR48018:SF170 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5D3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002338.4|UniProtKB=F7A4B8 F7A4B8 ADGRE1 PTHR12011:SF449 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020110.4|UniProtKB=F7EA17 F7EA17 MED19 PTHR22536:SF1 LUNG CANCER METASTASIS-RELATED LCMR1 PROTEIN MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 19 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000014384.5|UniProtKB=F6T7S8 F6T7S8 PLXNB1 PTHR22625:SF36 PLEXIN PLEXIN-B1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell differentiation#GO:0045595;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;system development#GO:0048731;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;regulation of axonogenesis#GO:0050770;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;positive regulation of cell differentiation#GO:0045597;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;nervous system development#GO:0007399;cellular component assembly#GO:0022607;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;regulation of biological quality#GO:0065008;positive regulation of axonogenesis#GO:0050772;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;synapse assembly#GO:0007416;response to stimulus#GO:0050896;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;positive regulation of multicellular organismal process#GO:0051240;regulation of cell shape#GO:0008360;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;negative regulation of biological process#GO:0048519 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Axon guidance mediated by semaphorins#P00007>plexinB1#P00328 MONDO|Ensembl=ENSMODG00000007579.3|UniProtKB=F7CPW3 F7CPW3 LOC130455180 PTHR23424:SF29 SERUM AMYLOID A SERUM AMYLOID A PROTEIN apolipoprotein#PC00052;transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000006724.4|UniProtKB=A0A5F8GG00 A0A5F8GG00 PTPA PTHR10012:SF0 SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR enzyme activator activity#GO:0008047;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;isomerase activity#GO:0016853;phosphatase activator activity#GO:0019211;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;enzyme regulator activity#GO:0030234;cis-trans isomerase activity#GO:0016859;molecular function activator activity#GO:0140677;protein phosphatase regulator activity#GO:0019888 mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;cellular process#GO:0009987;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 phosphatase activator#PC00182 MONDO|Ensembl=ENSMODG00000000802.4|UniProtKB=F6SRT4 F6SRT4 SERBP1 PTHR12299:SF29 HYALURONIC ACID-BINDING PROTEIN 4 SERPINE1 MRNA-BINDING PROTEIN 1 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000004749.3|UniProtKB=F6XIJ3 F6XIJ3 P2RY4 PTHR24231:SF21 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 4 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013462.4|UniProtKB=A0A5F8HCN8 A0A5F8HCN8 CELSR3 PTHR24026:SF38 FAT ATYPICAL CADHERIN-RELATED CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 3 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cell-cell adhesion#GO:0098609;axon development#GO:0061564;cellular process#GO:0009987;anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell adhesion#GO:0007155;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;adherens junction#GO:0005912;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000002859.4|UniProtKB=F6UVE9 F6UVE9 SART3 PTHR15481:SF5 RIBONUCLEIC ACID BINDING PROTEIN S1 SPLICEOSOME ASSOCIATED FACTOR 3, U4_U6 RECYCLING PROTEIN RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000007002.4|UniProtKB=A0A5F8G9I7 A0A5F8G9I7 RFXANK PTHR24124:SF4 ANKYRIN REPEAT FAMILY A DNA-BINDING PROTEIN RFXANK positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000008875.4|UniProtKB=F7CA97 F7CA97 PTHR26452:SF701 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 11L1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000001470.3|UniProtKB=F7AP82 F7AP82 CMPK1 PTHR23359:SF206 NUCLEOTIDE KINASE UMP-CMP KINASE catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776 ribonucleoside diphosphate metabolic process#GO:0009185;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;nucleoside diphosphate metabolic process#GO:0009132;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 kinase#PC00137;nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896;Salvage pyrimidine ribonucleotides#P02775>Cytidylate kinase#P03153;De novo pyrimidine ribonucleotides biosythesis#P02740>Uridylate kinase#P02924 MONDO|Ensembl=ENSMODG00000006647.4|UniProtKB=F7G431 F7G431 WRAP73 PTHR16220:SF1 WD REPEAT PROTEIN 8-RELATED WD REPEAT-CONTAINING PROTEIN WRAP73 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;organelle assembly#GO:0070925;nuclear division#GO:0000280 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000013806.5|UniProtKB=F6SXG6 F6SXG6 ZNF76 PTHR24388:SF63 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 76 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002812.3|UniProtKB=F7EJE2 F7EJE2 MAMDC2 PTHR23282:SF116 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000042737.1|UniProtKB=A0A5F8HDE4 A0A5F8HDE4 PTHR12396:SF62 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG BINDING DOMAIN PROTEIN 2 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;constitutive heterochromatin formation#GO:0140719;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000042953.1|UniProtKB=A0A5F8HGR5 A0A5F8HGR5 PTHR22245:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 144A-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 144A-RELATED MONDO|Ensembl=ENSMODG00000008131.4|UniProtKB=F7ELR7 F7ELR7 NUMA1 PTHR18902:SF24 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED NUCLEAR MITOTIC APPARATUS PROTEIN 1 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 establishment of organelle localization#GO:0051656;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;establishment of cell polarity#GO:0030010;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;regulation of protein localization#GO:0032880;spindle localization#GO:0051653;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;localization#GO:0051179;organelle localization#GO:0051640;establishment or maintenance of cell polarity#GO:0007163;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;establishment of spindle localization#GO:0051293;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;regulation of localization#GO:0032879;mitotic cell cycle process#GO:1903047;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;mitotic spindle pole#GO:0097431 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000041568.1|UniProtKB=A0A5F8GQJ1 A0A5F8GQJ1 LOC103099228 PTHR14949:SF25 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 CRYPTIC FAMILY PROTEIN 1B-RELATED signaling receptor binding#GO:0005102;binding#GO:0005488;receptor serine/threonine kinase binding#GO:0033612;protein binding#GO:0005515 animal gross anatomical part developmental process#GO:0160108;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;system development#GO:0048731;blood vessel morphogenesis#GO:0048514;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;determination of left/right symmetry#GO:0007368;cell differentiation#GO:0030154;circulatory system development#GO:0072359;specification of symmetry#GO:0009799;developmental process#GO:0032502;left/right pattern formation#GO:0060972;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;vasculature development#GO:0001944;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regionalization#GO:0003002;heart development#GO:0007507;vasculogenesis#GO:0001570;tube development#GO:0035295;determination of bilateral symmetry#GO:0009855 extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000013113.5|UniProtKB=A0A5F8H1K7 A0A5F8H1K7 SIPA1L3 PTHR15711:SF15 RAP GTPASE-ACTIVATING PROTEIN SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE PROTEIN 3 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;cell differentiation#GO:0030154;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;cell morphogenesis#GO:0000902;cell development#GO:0048468;anatomical structure morphogenesis#GO:0009653;establishment of cell polarity#GO:0030010;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein modulator#PC00022;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000002574.3|UniProtKB=A0A5F8HKK7 A0A5F8HKK7 GPR68 PTHR24234:SF5 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G PROTEIN-COUPLED RECEPTOR 68 cellular response to environmental stimulus#GO:0104004;cellular response to abiotic stimulus#GO:0071214;response to stimulus#GO:0050896;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000036608.1|UniProtKB=A0A5F8GRA1 A0A5F8GRA1 PTHR12297:SF5 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1A, MITOCHONDRIAL regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;cellular component assembly#GO:0022607;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000009626.4|UniProtKB=F6RDT4 F6RDT4 PCNX3 PTHR12372:SF4 PECANEX PECANEX-LIKE PROTEIN 3 MONDO|Ensembl=ENSMODG00000016162.4|UniProtKB=A0A5F8HK67 A0A5F8HK67 CAMK2B PTHR24347:SF403 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT BETA phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;calcium/calmodulin-dependent protein kinase activity#GO:0004683;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of neuronal synaptic plasticity#GO:0048168;regulation of signaling#GO:0023051;regulation of synaptic plasticity#GO:0048167 cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;postsynaptic specialization#GO:0099572;organelle#GO:0043226;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;postsynapse#GO:0098794;neuron projection#GO:0043005;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;postsynaptic density#GO:0014069;axon#GO:0030424 non-receptor serine/threonine protein kinase#PC00167 Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Gonadotropin-releasing hormone receptor pathway#P06664>Ca/CaMK II#P06735 MONDO|Ensembl=ENSMODG00000015772.5|UniProtKB=A0A5F8HGY7 A0A5F8HGY7 BRD1 PTHR13793:SF17 PHD FINGER PROTEINS BROMODOMAIN-CONTAINING PROTEIN 1 chromatin-protein adaptor activity#GO:0140463;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566 chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000011955.3|UniProtKB=F7CV17 F7CV17 LZTS2 PTHR19354:SF4 ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED ZIPPER PUTATIVE TUMOR SUPPRESSOR 2-RELATED regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 MONDO|Ensembl=ENSMODG00000012044.5|UniProtKB=A0A5F8GSR4 A0A5F8GSR4 RFX1 PTHR12619:SF23 RFX TRANSCRIPTION FACTOR FAMILY MHC CLASS II REGULATORY FACTOR RFX1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000042950.1|UniProtKB=A0A5F8GVX7 A0A5F8GVX7 PTHR11258:SF13 2-5 OLIGOADENYLATE SYNTHETASE 2'-5'-OLIGOADENYLATE SYNTHASE 1 RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;adenylyltransferase activity#GO:0070566;binding#GO:0005488;nucleic acid binding#GO:0003676;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 cytokine-mediated signaling pathway#GO:0019221;response to virus#GO:0009615;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;antiviral innate immune response#GO:0140374;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune response#GO:0006955;response to other organism#GO:0051707;biological regulation#GO:0065007;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;response to peptide#GO:1901652;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;negative regulation of biological process#GO:0048519;defense response to virus#GO:0051607;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829 nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000037463.1|UniProtKB=A0A5F8GM48 A0A5F8GM48 UBL3 PTHR13169:SF0 UBIQUITIN-LIKE PROTEIN 3 HCG-1 PROTEIN UBIQUITIN-LIKE PROTEIN 3 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000004949.3|UniProtKB=F7A6K0 F7A6K0 PLA2G10 PTHR11716:SF4 PHOSPHOLIPASE A2 FAMILY MEMBER GROUP 10 SECRETORY PHOSPHOLIPASE A2 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phospholipid binding#GO:0005543;cation binding#GO:0043169;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;small molecule binding#GO:0036094;lipase activity#GO:0016298;ion binding#GO:0043167;A2-type glycerophospholipase activity#GO:0004623;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;lipid binding#GO:0008289;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phosphatidylcholine metabolic process#GO:0046470;phosphatidylglycerol metabolic process#GO:0046471;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000051191.1|UniProtKB=A0A5F8GCW8 A0A5F8GCW8 monDomV1R1244 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037780.1|UniProtKB=A0A5F8GWX2 A0A5F8GWX2 PTHR35258:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 22 SPERMATOGENESIS-ASSOCIATED PROTEIN 22 regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;regulation of cellular process#GO:0050794;regulation of reproductive process#GO:2000241;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007 MONDO|Ensembl=ENSMODG00000050544.1|UniProtKB=A0A5F8G649 A0A5F8G649 PTHR11675:SF68 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 7 catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000024926.2|UniProtKB=F6ZP97 F6ZP97 PTHR15858:SF7 IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1 IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1 biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;establishment of localization in cell#GO:0051649;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of protein secretion#GO:0050714;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of protein secretion#GO:0050708;regulation of biological process#GO:0050789;regulation of secretion by cell#GO:1903530;regulation of protein localization#GO:0032880;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;regulation of establishment of protein localization#GO:0070201;cellular localization#GO:0051641;regulation of secretion#GO:0051046;localization#GO:0051179;positive regulation of secretion#GO:0051047;positive regulation of cellular component organization#GO:0051130 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000024344.2|UniProtKB=F7B5I5 F7B5I5 LOC100618109 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021307.4|UniProtKB=F7G3H8 F7G3H8 KCNMB3 PTHR10258:SF4 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-3 transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 detection of chemical stimulus#GO:0009593;action potential#GO:0001508;response to stimulus#GO:0050896;metal ion transport#GO:0030001;nervous system process#GO:0050877;cell communication#GO:0007154;response to calcium ion#GO:0051592;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;detection of stimulus#GO:0051606;cellular process#GO:0009987;multicellular organismal process#GO:0032501;potassium ion transport#GO:0006813;response to chemical#GO:0042221;biological regulation#GO:0065007;transport#GO:0006810;response to metal ion#GO:0010038;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transmission of nerve impulse#GO:0019226;system process#GO:0003008 cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000013156.3|UniProtKB=F6PHL0 F6PHL0 LOC100020697 PTHR24012:SF409 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000023566.2|UniProtKB=F7GBY1 F7GBY1 ZNF672 PTHR24388:SF93 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 672 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000013836.4|UniProtKB=F6SDJ8 F6SDJ8 PTHR43591:SF101 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 27 methyltransferase#PC00155;transferase#PC00220 MONDO|Ensembl=ENSMODG00000020759.4|UniProtKB=A0A5F8GFL0 A0A5F8GFL0 JADE1 PTHR13793:SF79 PHD FINGER PROTEINS PROTEIN JADE-1 histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;chromatin-protein adaptor activity#GO:0140463 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000008596.4|UniProtKB=F7BTZ0 F7BTZ0 PDZD4 PTHR15545:SF4 PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4 PDZ DOMAIN-CONTAINING PROTEIN 4 MONDO|Ensembl=ENSMODG00000025567.3|UniProtKB=F6UHS0 F6UHS0 HOATZ PTHR47231:SF1 UPF0722 PROTEIN C11ORF88 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN HOATZ MONDO|Ensembl=ENSMODG00000014781.4|UniProtKB=F7G6X8 F7G6X8 SRSF1 PTHR23147:SF44 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 1 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;membraneless organelle#GO:0043228;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000015410.4|UniProtKB=A0A5F8GQW4 A0A5F8GQW4 RFX3 PTHR12619:SF20 RFX TRANSCRIPTION FACTOR FAMILY TRANSCRIPTION FACTOR RFX3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000024106.2|UniProtKB=F6WKK5 F6WKK5 TRIM13 PTHR24103:SF609 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM13 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of macroautophagy#GO:0016241;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;defense response to other organism#GO:0098542;proteasomal protein catabolic process#GO:0010498;response to biotic stimulus#GO:0009607;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of macroautophagy#GO:0016239;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of catabolic process#GO:0009894;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of canonical NF-kappaB signal transduction#GO:0043122;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000007153.4|UniProtKB=F6RY91 F6RY91 KLHL33 PTHR45632:SF14 LD33804P KELCH-LIKE PROTEIN 33 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000800.4|UniProtKB=A0A5F8GUV5 A0A5F8GUV5 BRD9 PTHR22881:SF4 BROMODOMAIN CONTAINING PROTEIN BROMODOMAIN-CONTAINING PROTEIN 9 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000020112.3|UniProtKB=F7EA08 F7EA08 TMX2 PTHR15853:SF2 THIOREDOXIN-RELATED THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036 multicellular organismal process#GO:0032501;brain development#GO:0007420;central nervous system development#GO:0007417;head development#GO:0060322;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;system development#GO:0048731 organelle membrane contact site#GO:0044232;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;mitochondria-associated endoplasmic reticulum membrane contact site#GO:0044233;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000001002.4|UniProtKB=F7E9J4 F7E9J4 DLG5 PTHR46360:SF1 DISKS LARGE HOMOLOG 5 DISKS LARGE HOMOLOG 5 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of hippo signaling#GO:0035331;negative regulation of intracellular signal transduction#GO:1902532;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000027551.2|UniProtKB=K7E406 K7E406 PTHR22957:SF466 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SI:DKEY-238D18.4 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000005694.2|UniProtKB=F6UKW5 F6UKW5 LOC100031312 PTHR26453:SF110 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2G6 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008980.5|UniProtKB=A0A5F8GYL9 A0A5F8GYL9 PLXNA3 PTHR22625:SF32 PLEXIN PLEXIN-A3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;anatomical structure development#GO:0048856;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;neuron projection morphogenesis#GO:0048812;regulation of cell differentiation#GO:0045595;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;regulation of plasma membrane bounded cell projection organization#GO:0120035;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;axon guidance#GO:0007411;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;neuron development#GO:0048666;axonogenesis#GO:0007409;cell junction assembly#GO:0034329;negative regulation of biological process#GO:0048519;positive regulation of multicellular organismal process#GO:0051240;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell morphogenesis#GO:0000902;synapse assembly#GO:0007416;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell development#GO:0048468;positive regulation of cell differentiation#GO:0045597;neuron differentiation#GO:0030182;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell development#GO:0010720;nervous system development#GO:0007399;regulation of nervous system development#GO:0051960;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;developmental process#GO:0032502;cellular developmental process#GO:0048869;axon development#GO:0061564;negative regulation of cell adhesion#GO:0007162;plasma membrane bounded cell projection organization#GO:0120036;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;positive regulation of axonogenesis#GO:0050772;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;regulation of multicellular organismal development#GO:2000026;cell projection organization#GO:0030030;cell differentiation#GO:0030154;positive regulation of nervous system development#GO:0051962;signaling#GO:0023052;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;regulation of axonogenesis#GO:0050770;cell projection morphogenesis#GO:0048858;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006706.4|UniProtKB=F7DGV8 F7DGV8 CRAT PTHR22589:SF50 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;carnitine metabolic process#GO:0009437;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000016194.4|UniProtKB=A0A5F8HFJ6 A0A5F8HFJ6 STK4 PTHR48015:SF32 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE 4 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of signal transduction#GO:0009968;hippo signaling#GO:0035329;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of apoptotic process#GO:0043065;regulation of MAPK cascade#GO:0043408;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000005876.3|UniProtKB=F6SNA6 F6SNA6 LOC103093777 PTHR24404:SF129 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 835 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000050268.1|UniProtKB=A0A5F8HBU5 A0A5F8HBU5 PTHR47385:SF17 CALPONIN CALPONIN-3 cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000040773.1|UniProtKB=F6PZL9 F6PZL9 LOC100021655 PTHR26450:SF43 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010351.3|UniProtKB=F6RQ25 F6RQ25 LOC100028327 PTHR26452:SF977 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013755.6|UniProtKB=F6WS29 F6WS29 UBN2 PTHR21669:SF10 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS UBINUCLEIN-2 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004750.3|UniProtKB=F6XIH7 F6XIH7 USP35 PTHR24006:SF660 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 35 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000005180.4|UniProtKB=F7DP14 F7DP14 CNIH4 PTHR12290:SF19 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 4 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000000705.3|UniProtKB=F6WLG6 F6WLG6 SLC3A1 PTHR10357:SF240 ALPHA-GLUCOSIDASE FAMILY MEMBER AMINO ACID TRANSPORTER HEAVY CHAIN SLC3A1 oligosaccharide metabolic process#GO:0009311;carbohydrate catabolic process#GO:0016052;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;amino acid transport#GO:0006865;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;cellular process#GO:0009987;primary metabolic process#GO:0044238 cluster of actin-based cell projections#GO:0098862;cell projection membrane#GO:0031253;apical part of cell#GO:0045177;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;brush border membrane#GO:0031526;brush border#GO:0005903;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 amylase#PC00048;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000046339.1|UniProtKB=A0A5F8H0G1 A0A5F8H0G1 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000047213.1|UniProtKB=F6SS99 F6SS99 LOC100028338 PTHR26452:SF256 OLFACTORY RECEPTOR OLFACTORY RECEPTOR FAMILY 12 SUBFAMILY J MEMBER 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000049174.1|UniProtKB=A0A5F8GHR4 A0A5F8GHR4 PTHR45945:SF1 REGULATOR OF G-PROTEIN SIGNALING LOCO REGULATOR OF G PROTEIN SIGNALING 12 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789 membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 MONDO|Ensembl=ENSMODG00000000607.3|UniProtKB=F6TB90 F6TB90 PTHR46271:SF2 HOMEOBOX PROTEIN, PUTATIVE-RELATED RETINA AND ANTERIOR NEURAL FOLD HOMEOBOX PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000007438.3|UniProtKB=F7DWA7 F7DWA7 TSEN54 PTHR21027:SF1 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54 RNA biosynthetic process#GO:0032774;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000008467.4|UniProtKB=F7GES2 F7GES2 monDomV1R1237 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001088.4|UniProtKB=F7GHP1 F7GHP1 ST3GAL1 PTHR46032:SF6 ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1 CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 1 sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule modification#GO:0043412;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transferase#PC00220 MONDO|Ensembl=ENSMODG00000022938.1|UniProtKB=F6PYW1 F6PYW1 LOC100020425 PTHR26450:SF35 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000180.5|UniProtKB=F6TGA6 F6TGA6 AMOTL1 PTHR14826:SF12 ANGIOMOTIN ANGIOMOTIN-LIKE PROTEIN 1 actin filament-based process#GO:0030029;system development#GO:0048731;intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;establishment of cell polarity#GO:0030010;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;regulation of cell migration#GO:0030334;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;tube development#GO:0035295;multicellular organismal process#GO:0032501;cell migration#GO:0016477;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;angiogenesis#GO:0001525;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;cellular component organization#GO:0016043;signaling#GO:0023052;circulatory system development#GO:0072359;response to stimulus#GO:0050896;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;hippo signaling#GO:0035329 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;bicellular tight junction#GO:0005923;apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000009689.4|UniProtKB=F6YBH6 F6YBH6 CYP11A1 PTHR24279:SF3 CYTOCHROME P450 CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME, MITOCHONDRIAL oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;response to chemical#GO:0042221;steroid metabolic process#GO:0008202;response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;regulation of biological quality#GO:0065008;olefinic compound metabolic process#GO:0120254;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;ketone metabolic process#GO:0042180;response to endogenous stimulus#GO:0009719;regulation of hormone levels#GO:0010817;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;cellular response to nitrogen compound#GO:1901699;lipid biosynthetic process#GO:0008610;hormone metabolic process#GO:0042445;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;biosynthetic process#GO:0009058;response to nitrogen compound#GO:1901698;cellular response to peptide hormone stimulus#GO:0071375;hormone biosynthetic process#GO:0042446;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000038488.1|UniProtKB=A0A5F8GP88 A0A5F8GP88 LOC100019242 PTHR24381:SF27 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 180 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009990.2|UniProtKB=F6USR6 F6USR6 TACO1 PTHR12532:SF12 TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1 TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of protein metabolic process#GO:0051247;positive regulation of translation#GO:0045727;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000011338.4|UniProtKB=F6WHW4 F6WHW4 SOX4 PTHR10270:SF27 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-4 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 sensory organ development#GO:0007423;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;camera-type eye morphogenesis#GO:0048593;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;camera-type eye development#GO:0043010;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;visual system development#GO:0150063;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;animal organ development#GO:0048513;negative regulation of macromolecule biosynthetic process#GO:0010558;sensory system development#GO:0048880;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;head development#GO:0060322;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;eye development#GO:0001654;negative regulation of biological process#GO:0048519;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;sensory organ morphogenesis#GO:0090596;negative regulation of metabolic process#GO:0009892 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 MONDO|Ensembl=ENSMODG00000000745.3|UniProtKB=F6VPU6 F6VPU6 NPY PTHR10533:SF5 NEUROPEPTIDE Y/PANCREATIC HORMONE/PEPTIDE YY PRO-NEUROPEPTIDE Y molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;neuropeptide hormone activity#GO:0005184;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;neuropeptide receptor binding#GO:0071855;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 feeding behavior#GO:0007631;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000018453.4|UniProtKB=F7CUD8 F7CUD8 CEP19 PTHR31539:SF1 CENTROSOMAL PROTEIN OF 19K CEP19 CENTROSOMAL PROTEIN OF 19 KDA Golgi to plasma membrane transport#GO:0006893;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;post-Golgi vesicle-mediated transport#GO:0006892;trans-Golgi to periciliary membrane compartment transport#GO:0097712;cilium organization#GO:0044782;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;localization within membrane#GO:0051668;organelle assembly#GO:0070925;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;vesicle-mediated transport to the plasma membrane#GO:0098876;microtubule-based process#GO:0007017;microtubule anchoring at microtubule organizing center#GO:0072393;cellular component organization or biogenesis#GO:0071840;microtubule anchoring#GO:0034453;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031 spindle pole#GO:0000922;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000044486.1|UniProtKB=A0A5F8HCB7 A0A5F8HCB7 MPDU1 PTHR12226:SF5 MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 PROTEIN cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate biosynthetic process#GO:0016051;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311;oligosaccharide biosynthetic process#GO:0009312 MONDO|Ensembl=ENSMODG00000045828.1|UniProtKB=A0A5F8HC20 A0A5F8HC20 GLRX PTHR46185:SF1 GLUTAREDOXIN-1 GLUTAREDOXIN-1 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000001756.3|UniProtKB=F6WZJ6 F6WZJ6 TMEM174 PTHR31020:SF1 TRANSMEMBRANE PROTEIN 174 TRANSMEMBRANE PROTEIN 174 MONDO|Ensembl=ENSMODG00000014013.3|UniProtKB=F6VAC1 F6VAC1 LIN37 PTHR31336:SF3 LIN37 HOMOLOG PROTEIN LIN-37 HOMOLOG negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000003447.4|UniProtKB=F7DWV5 F7DWV5 EPC2 PTHR14898:SF4 ENHANCER OF POLYCOMB ENHANCER OF POLYCOMB HOMOLOG 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000014989.4|UniProtKB=A0A5F8HB99 A0A5F8HB99 KLHL3 PTHR24412:SF179 KELCH PROTEIN KELCH-LIKE PROTEIN 3 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 sodium ion transport#GO:0006814;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;homeostatic process#GO:0042592;metal ion transport#GO:0030001;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;monoatomic ion transport#GO:0006811;protein metabolic process#GO:0019538;monoatomic cation transport#GO:0006812;localization#GO:0051179;renal system process#GO:0003014;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;proteasomal protein catabolic process#GO:0010498;multicellular organismal process#GO:0032501;transport#GO:0006810;chemical homeostasis#GO:0048878;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;system process#GO:0003008;establishment of localization#GO:0051234;renal absorption#GO:0070293;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000001760.4|UniProtKB=F7DXA3 F7DXA3 CRMP1 PTHR11647:SF54 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 1 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;dihydropyrimidinase activity#GO:0004157;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;pyrimidine nucleobase metabolic process#GO:0006206;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;primary metabolic process#GO:0044238;pyrimidine nucleobase catabolic process#GO:0006208;nucleobase-containing compound metabolic process#GO:0006139;nucleobase catabolic process#GO:0046113;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339 MONDO|Ensembl=ENSMODG00000005658.4|UniProtKB=F6VL66 F6VL66 TGFB3 PTHR11848:SF34 TGF-BETA FAMILY TRANSFORMING GROWTH FACTOR BETA-3 PROPROTEIN signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125 cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;response to transforming growth factor beta#GO:0071559;circulatory system development#GO:0072359;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;transforming growth factor beta receptor signaling pathway#GO:0007179;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000051445.1|UniProtKB=A0A5F8HJ22 A0A5F8HJ22 APOA1 PTHR18976:SF11 APOLIPOPROTEIN APOLIPOPROTEIN A-I molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;binding#GO:0005488;molecular function activator activity#GO:0140677;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;enzyme regulator activity#GO:0030234;sterol transfer activity#GO:0120015;transporter activity#GO:0005215;enzyme activator activity#GO:0008047;phospholipid binding#GO:0005543;molecular function regulator activity#GO:0098772;cholesterol transfer activity#GO:0120020 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;transport#GO:0006810;sterol transport#GO:0015918;establishment of localization#GO:0051234;sterol metabolic process#GO:0016125;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;cholesterol efflux#GO:0033344;cellular process#GO:0009987;lipid transport#GO:0006869;phospholipid transport#GO:0015914;steroid metabolic process#GO:0008202;lipid localization#GO:0010876;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;organophosphate ester transport#GO:0015748;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;homeostatic process#GO:0042592 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;very-low-density lipoprotein particle#GO:0034361;vesicle#GO:0031982;plasma lipoprotein particle#GO:0034358;membrane-bounded organelle#GO:0043227;high-density lipoprotein particle#GO:0034364;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;protein-lipid complex#GO:0032994;lipoprotein particle#GO:1990777 transfer/carrier protein#PC00219;apolipoprotein#PC00052 MONDO|Ensembl=ENSMODG00000000415.3|UniProtKB=A0A5F8HI09 A0A5F8HI09 PTHR13031:SF0 RIBONUCLEASE P SUBUNIT P30 RIBONUCLEASE P PROTEIN SUBUNIT P30 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654 endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;multimeric ribonuclease P complex#GO:0030681;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleolar ribonuclease P complex#GO:0005655;endonuclease complex#GO:1905348;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 endoribonuclease#PC00094;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000013226.4|UniProtKB=F7EDE1 F7EDE1 PTHR23406:SF17 MALIC ENZYME-RELATED NADP-DEPENDENT MALIC ENZYME oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176 Pyruvate metabolism#P02772>Malic enzyme#P03136 MONDO|Ensembl=ENSMODG00000039909.1|UniProtKB=A0A5F8G5A0 A0A5F8G5A0 PTHR42748:SF10 NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER NMRA-LIKE FAMILY DOMAIN-CONTAINING PROTEIN 1 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000019933.3|UniProtKB=F6V7I8 F6V7I8 monDomV1R1254 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000047544.1|UniProtKB=A0A5F8HF85 A0A5F8HF85 PTHR12845:SF7 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 15 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of actin filament-based process#GO:0032970;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000000853.4|UniProtKB=A0A5F8GF00 A0A5F8GF00 DUSP13A PTHR45682:SF3 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE 13A hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000045392.1|UniProtKB=A0A5F8GJ31 A0A5F8GJ31 PTHR15028:SF10 CD72-RELATED B-CELL DIFFERENTIATION ANTIGEN CD72 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 negative regulation of response to stimulus#GO:0048585;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of B cell receptor signaling pathway#GO:0050855;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000013595.4|UniProtKB=F6VVT7 F6VVT7 PRMT1 PTHR11006:SF54 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;histone modifying activity#GO:0140993;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000002416.4|UniProtKB=F7EGW4 F7EGW4 SLC9A4 PTHR10110:SF103 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 4 monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139 monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000000716.3|UniProtKB=F6W6L0 F6W6L0 MPST PTHR11364:SF25 THIOSULFATE SULFERTANSFERASE 3-MERCAPTOPYRUVATE SULFURTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;tRNA thio-modification#GO:0034227;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;tRNA wobble position uridine thiolation#GO:0002143 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transferase#PC00220 MONDO|Ensembl=ENSMODG00000005075.5|UniProtKB=A0A5F8GM08 A0A5F8GM08 SCYL2 PTHR12984:SF6 SCY1-RELATED S/T PROTEIN KINASE-LIKE SCY1-LIKE PROTEIN 2 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000003991.4|UniProtKB=F6X6W5 F6X6W5 CNTN3 PTHR12231:SF224 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN CONTACTIN-3 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000010964.4|UniProtKB=F7G1W1 F7G1W1 ZNF638 PTHR15592:SF1 MATRIN 3/NUCLEAR PROTEIN 220-RELATED ZINC FINGER PROTEIN 638 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000038632.1|UniProtKB=A0A5F8HDH0 A0A5F8HDH0 TMEM50A PTHR13180:SF4 SMALL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 50A cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907 vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000045504.1|UniProtKB=A0A5F8H0N4 A0A5F8H0N4 PTHR47658:SF1 HIGH MOBILITY GROUP B PROTEIN 12-RELATED MEIOSIS INITIATOR PROTEIN MONDO|Ensembl=ENSMODG00000017108.4|UniProtKB=F6UKC1 F6UKC1 ADO PTHR22966:SF76 2-AMINOETHANETHIOL DIOXYGENASE 2-AMINOETHANETHIOL DIOXYGENASE dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 response to chemical#GO:0042221;response to stimulus#GO:0050896;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950;cellular response to hypoxia#GO:0071456;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to hypoxia#GO:0001666;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000003119.4|UniProtKB=A0A5F8GF14 A0A5F8GF14 PFKL PTHR13697:SF14 PHOSPHOFRUCTOKINASE ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, LIVER TYPE anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;carbohydrate derivative binding#GO:0097367 small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091 cytosol#GO:0005829;membrane#GO:0016020;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 transferase#PC00220;kinase#PC00137;carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphofructokinase-1#P00672 MONDO|Ensembl=ENSMODG00000014105.4|UniProtKB=H9H6N9 H9H6N9 PRPS1 PTHR10210:SF130 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 1-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000044825.1|UniProtKB=K7E303 K7E303 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000020447.4|UniProtKB=F7AQG5 F7AQG5 PTHR11108:SF1 FERROCHELATASE FERROCHELATASE, MITOCHONDRIAL lyase activity#GO:0016829;catalytic activity#GO:0003824 metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;porphyrin-containing compound biosynthetic process#GO:0006779;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440;cellular process#GO:0009987;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 lyase#PC00144 Heme biosynthesis#P02746>Ferrochelatase#P02972 MONDO|Ensembl=ENSMODG00000020687.2|UniProtKB=F7DKI6 F7DKI6 DNAJB14 PTHR43908:SF4 AT29763P-RELATED DNAJ HOMOLOG SUBFAMILY B MEMBER 14 heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 primary metabolic process#GO:0044238;response to misfolded protein#GO:0051788;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;cellular response to misfolded protein#GO:0071218;macromolecule metabolic process#GO:0043170 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000009017.3|UniProtKB=F7BPM8 F7BPM8 LRRC49 PTHR45973:SF8 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 49 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000006700.3|UniProtKB=F7DH47 F7DH47 PKIA PTHR15416:SF2 CAMP-DEPENDENT PROTEIN KINASE INHIBITOR/PKI CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;protein kinase regulator activity#GO:0019887;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;kinase inhibitor activity#GO:0019210 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase inhibitor#PC00139;kinase modulator#PC00140 MONDO|Ensembl=ENSMODG00000015671.4|UniProtKB=F7EI44 F7EI44 YTHDC2 PTHR18934:SF213 ATP-DEPENDENT RNA HELICASE 3'-5' RNA HELICASE YTHDC2 macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000029056.2|UniProtKB=K7E005 K7E005 NPS PTHR36679:SF1 NEUROPEPTIDE S NEUROPEPTIDE S regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of trans-synaptic signaling#GO:0099177;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391;positive regulation of signaling#GO:0023056;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of signaling#GO:0023051;positive regulation of synaptic transmission#GO:0050806 MONDO|Ensembl=ENSMODG00000043107.1|UniProtKB=A0A5F8HII6 A0A5F8HII6 CDCP2 PTHR24251:SF47 OVOCHYMASE-RELATED CUB DOMAIN-CONTAINING PROTEIN 2 protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000049814.1|UniProtKB=A0A5F8GNH1 A0A5F8GNH1 IBSP PTHR10345:SF0 BONE SIALOPROTEIN 2 INTEGRIN-BINDING SIALOPROTEIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;bone mineralization#GO:0030282;developmental process#GO:0032502;biomineral tissue development#GO:0031214;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;cellular process#GO:0009987;tissue development#GO:0009888;multicellular organismal process#GO:0032501;ossification#GO:0001503 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000004736.4|UniProtKB=F6Y128 F6Y128 AWAT1 PTHR12317:SF16 DIACYLGLYCEROL O-ACYLTRANSFERASE ACYL-COA WAX ALCOHOL ACYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 neutral lipid metabolic process#GO:0006638;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000005707.4|UniProtKB=A0A5F8H4H2 A0A5F8H4H2 WDR27 PTHR44525:SF1 WD REPEAT-CONTAINING PROTEIN 27 WD REPEAT-CONTAINING PROTEIN 27 MONDO|Ensembl=ENSMODG00000010169.3|UniProtKB=A0A5F8H4V0 A0A5F8H4V0 LOC100030208 PTHR26451:SF970 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000019299.4|UniProtKB=F6RZ31 F6RZ31 TLCD1 PTHR13439:SF5 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 1 regulation of biological quality#GO:0065008;regulation of membrane lipid distribution#GO:0097035;plasma membrane organization#GO:0007009;cellular component organization or biogenesis#GO:0071840;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;membrane organization#GO:0061024;cellular component assembly#GO:0022607;cellular process#GO:0009987;membrane assembly#GO:0071709;cellular component organization#GO:0016043;lipid homeostasis#GO:0055088;cellular component biogenesis#GO:0044085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000046673.1|UniProtKB=K7E605 K7E605 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000028551.2|UniProtKB=K7E4L3 K7E4L3 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000028884.2|UniProtKB=K7E2E4 K7E2E4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000037506.1|UniProtKB=A0A5F8HFS7 A0A5F8HFS7 PTHR11434:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT ND4L NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4L membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000015395.3|UniProtKB=F6TK02 F6TK02 CRIM1 PTHR46439:SF1 CYSTEINE-RICH MOTOR NEURON 1 PROTEIN CYSTEINE-RICH MOTOR NEURON 1 PROTEIN MONDO|Gene=SPINK1|UniProtKB=P81635 P81635 SPINK1 PTHR21312:SF28 SERINE PROTEASE INHIBITOR OVOINHIBITOR-RELATED protein-binding activity modulator#PC00095;protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000003264.4|UniProtKB=F6T013 F6T013 LRIG1 PTHR24373:SF273 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000036897.1|UniProtKB=A0A5F8HBG1 A0A5F8HBG1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016058.3|UniProtKB=F7GIX5 F7GIX5 PTHR26453:SF669 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10C1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000050046.1|UniProtKB=F6RPZ8 F6RPZ8 PIBF1 PTHR18950:SF1 PROGESTERONE-INDUCED BLOCKING FACTOR 1 PROGESTERONE-INDUCED-BLOCKING FACTOR 1 cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000039035.1|UniProtKB=A0A5F8GCC8 A0A5F8GCC8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000041910.1|UniProtKB=A0A5F8H990 A0A5F8H990 PTHR23048:SF66 MYOSIN LIGHT CHAIN 1, 3 CALMODULIN 2 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000046737.1|UniProtKB=A0A5F8HJQ6 A0A5F8HJQ6 monDomV1R1262 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008071.4|UniProtKB=A0A5F8H025 A0A5F8H025 PTHR15444:SF4 SECRETED PHOSPHOPROTEIN 24 SECRETED PHOSPHOPROTEIN 24 MONDO|Ensembl=ENSMODG00000038051.1|UniProtKB=A0A5F8GN95 A0A5F8GN95 ZW10 PTHR12205:SF0 CENTROMERE/KINETOCHORE PROTEIN ZW10 CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG regulation of mitotic sister chromatid segregation#GO:0033047;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of organelle organization#GO:0010639;regulation of cellular process#GO:0050794;transport#GO:0006810;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;nuclear division#GO:0000280;cellular localization#GO:0051641;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of chromosome segregation#GO:0051985;cellular component organization or biogenesis#GO:0071840;establishment of localization in cell#GO:0051649;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;negative regulation of sister chromatid segregation#GO:0033046;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;vesicle-mediated transport#GO:0016192;negative regulation of chromosome organization#GO:2001251;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular signal transduction#GO:0035556;localization#GO:0051179;cell communication#GO:0007154;organelle fission#GO:0048285;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of cellular component organization#GO:0051129;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;establishment of localization#GO:0051234;regulation of mitotic cell cycle#GO:0007346;mitotic sister chromatid segregation#GO:0000070;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;chromosome segregation#GO:0007059;regulation of chromosome segregation#GO:0051983;Golgi vesicle transport#GO:0048193;negative regulation of cell cycle#GO:0045786;mitotic spindle assembly checkpoint signaling#GO:0007094;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075 condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;endoplasmic reticulum#GO:0005783;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;spindle#GO:0005819;vesicle tethering complex#GO:0099023;endoplasmic reticulum protein-containing complex#GO:0140534;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;kinetochore#GO:0000776;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;spindle microtubule#GO:0005876;microtubule#GO:0005874 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000021432.3|UniProtKB=A0A5F8GM98 A0A5F8GM98 PTHR45752:SF40 LEUCINE-RICH REPEAT-CONTAINING VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8B monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509 cellular response to stimulus#GO:0051716;carbohydrate derivative transport#GO:1901264;monoatomic anion transport#GO:0006820;carboxylic acid transmembrane transport#GO:1905039;regulation of cellular process#GO:0050794;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;intracellular signal transduction#GO:0035556;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;cell communication#GO:0007154;nitrogen compound transport#GO:0071705;aspartate transmembrane transport#GO:0015810;monoatomic ion transmembrane transport#GO:0034220;dicarboxylic acid transport#GO:0006835;biological regulation#GO:0065007;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;cellular process#GO:0009987;signal transduction#GO:0007165;monoatomic anion transmembrane transport#GO:0098656;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;import into cell#GO:0098657 intracellular anatomical structure#GO:0005622;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000058.4|UniProtKB=F6REE2 F6REE2 NPSR1 PTHR24244:SF2 NEUROPEPTIDE S RECEPTOR NEUROPEPTIDE S RECEPTOR molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of transmembrane transport#GO:0034762;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;regulation of monoatomic ion transmembrane transport#GO:0034765 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010824.4|UniProtKB=H9H6F8 H9H6F8 OVCH1 PTHR24252:SF8 ACROSIN-RELATED ACROSIN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;sexual reproduction#GO:0019953;catabolic process#GO:0009056;reproductive process#GO:0022414;fertilization#GO:0009566;single fertilization#GO:0007338;primary metabolic process#GO:0044238;cellular process#GO:0009987;acrosome reaction#GO:0007340 intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000015576.4|UniProtKB=F7AIM3 F7AIM3 MMP17 PTHR10201:SF21 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-17 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 extracellular structure organization#GO:0043062;metabolic process#GO:0008152;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;cellular process#GO:0009987;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141 MONDO|Ensembl=ENSMODG00000021415.4|UniProtKB=F7CBQ6 F7CBQ6 RNMT PTHR12189:SF2 MRNA GUANINE-7- METHYLTRANSFERASE MRNA CAP GUANINE-N(7) METHYLTRANSFERASE transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000008835.4|UniProtKB=F7CUX4 F7CUX4 UGGT2 PTHR11226:SF1 UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;glucosyltransferase activity#GO:0046527 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000015958.3|UniProtKB=F7FRF9 F7FRF9 CDA PTHR11644:SF2 CYTIDINE DEAMINASE CYTIDINE DEAMINASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239 nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule biosynthetic process#GO:0044283;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing small molecule catabolic process#GO:0034656;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;nucleoside catabolic process#GO:0009164 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 deaminase#PC00088 Pyrimidine Metabolism#P02771>Cytidine Deaminase#P03130;Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144 MONDO|Ensembl=ENSMODG00000046216.1|UniProtKB=A0A5F8G7B4 A0A5F8G7B4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000046185.1|UniProtKB=F6X645 F6X645 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000020823.3|UniProtKB=F6RM38 F6RM38 LIM2 PTHR10671:SF9 EPITHELIAL MEMBRANE PROTEIN-RELATED LENS FIBER MEMBRANE INTRINSIC PROTEIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000018505.4|UniProtKB=F7B3R6 F7B3R6 RYK PTHR24416:SF349 TYROSINE-PROTEIN KINASE RECEPTOR INACTIVE TYROSINE-PROTEIN KINASE RYK catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of signaling#GO:0023056;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of intracellular signal transduction#GO:1902533;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024099.2|UniProtKB=F6Y1T6 F6Y1T6 PTHR24072:SF153 RHO FAMILY GTPASE TRANSFORMING PROTEIN RHOA nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899 actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;contractile actin filament bundle assembly#GO:0030038;cell migration#GO:0016477;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;regulation of cytoskeleton organization#GO:0051493;cellular response to stimulus#GO:0051716;actin filament bundle assembly#GO:0051017;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;intracellular signaling cassette#GO:0141124;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;Rho protein signal transduction#GO:0007266;stress fiber assembly#GO:0043149;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;actomyosin structure organization#GO:0031032;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;actin filament bundle organization#GO:0061572;regulation of biological process#GO:0050789 cytosol#GO:0005829;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cell division site#GO:0032153;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell junction#GO:0030054;cleavage furrow#GO:0032154;postsynapse#GO:0098794;dendritic spine#GO:0043197;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular anatomical structure#GO:0005622 G-protein#PC00020;small GTPase#PC00208 Integrin signalling pathway#P00034>Rho#P00948;Ras Pathway#P04393>Rho#P04578;CCKR signaling map#P06959>RHOA-GDP#P07019;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoA#P00740;Axon guidance mediated by semaphorins#P00007>Rho#P00341;CCKR signaling map#P06959>RHOA-GTP#P07188;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rho#P00860;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>RhoA#P05938;Angiogenesis#P00005>GTPase#P00254 MONDO|Ensembl=ENSMODG00000023754.3|UniProtKB=F6TEI1 F6TEI1 PTHR46030:SF1 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6 RNA_DNA DEMETHYLASE ALKBH6-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;dioxygenase activity#GO:0051213 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000016219.3|UniProtKB=F7FM10 F7FM10 R3HDML PTHR10334:SF62 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR R3HDML cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000049494.1|UniProtKB=A0A5F8GIJ5 A0A5F8GIJ5 PTHR22909:SF23 GOLGI INTEGRAL MEMBRANE PROTEIN 4 GOLGI INTEGRAL MEMBRANE PROTEIN 4-LIKE intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000023834.3|UniProtKB=F6U906 F6U906 BAG5 PTHR12329:SF2 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 5 nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein stability#GO:0031647;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;protein stabilization#GO:0050821;regulation of protein modification process#GO:0031399;regulation of protein ubiquitination#GO:0031396;negative regulation of cellular process#GO:0048523;regulation of cellular component biogenesis#GO:0044087;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;regulation of post-translational protein modification#GO:1901873;negative regulation of protein ubiquitination#GO:0031397 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;nucleus#GO:0005634 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000041066.1|UniProtKB=A0A5F8G2K2 A0A5F8G2K2 EFNA5 PTHR11304:SF33 EPHRIN EPHRIN-A5 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of actin cytoskeleton organization#GO:0032956;nervous system development#GO:0007399;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of organelle organization#GO:0033043;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000009436.4|UniProtKB=F7AYT6 F7AYT6 LOC100024446 PTHR13976:SF60 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000001631.3|UniProtKB=A0A5F8GGF0 A0A5F8GGF0 ERLEC1 PTHR15414:SF0 OS-9-RELATED ENDOPLASMIC RETICULUM LECTIN 1 response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular localization#GO:0051641;response to unfolded protein#GO:0006986;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cell communication#GO:0007154;localization#GO:0051179;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000011962.3|UniProtKB=H9H6J2 H9H6J2 SLC16A2 PTHR11360:SF123 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 8 secondary active transmembrane transporter activity#GO:0015291;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;monocarboxylic acid transmembrane transporter activity#GO:0008028 hormone transport#GO:0009914;regulation of hormone levels#GO:0010817;transport#GO:0006810;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000008157.4|UniProtKB=F7ELB5 F7ELB5 WAC PTHR15911:SF6 WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL RNA polymerase binding#GO:0070063;chromatin binding#GO:0003682;enzyme binding#GO:0019899;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993 regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of autophagy#GO:0010506;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000001476.3|UniProtKB=A0A5F8GD92 A0A5F8GD92 MYL11 PTHR23049:SF10 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 11 myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169 muscle organ development#GO:0007517;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;anatomical structure development#GO:0048856;animal organ development#GO:0048513;muscle tissue development#GO:0060537;skeletal muscle tissue development#GO:0007519;muscle structure development#GO:0061061;tissue development#GO:0009888 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000025737.3|UniProtKB=F6T210 F6T210 HEATR4 PTHR12697:SF20 PBS LYASE HEAT-LIKE PROTEIN HEAT REPEAT-CONTAINING PROTEIN 4 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 lyase#PC00144 MONDO|Ensembl=ENSMODG00000025755.3|UniProtKB=A0A5F8GJV1 A0A5F8GJV1 LOC100021456 PTHR12015:SF111 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 17 cytokine#PC00083 MONDO|Ensembl=ENSMODG00000010220.3|UniProtKB=H9H6E0 H9H6E0 NUDT22 PTHR31835:SF1 URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE NUDT22 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000012872.3|UniProtKB=A0A5F8GJQ3 A0A5F8GJQ3 LYPLA2 PTHR10655:SF13 LYSOPHOSPHOLIPASE-RELATED ACYL-PROTEIN THIOESTERASE 2 lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;carboxylic ester hydrolase activity#GO:0052689;thiolester hydrolase activity#GO:0016790;palmitoyl hydrolase activity#GO:0098599;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;catalytic activity, acting on a protein#GO:0140096 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;regulation of localization#GO:0032879;regulation of transport#GO:0051049;lipid catabolic process#GO:0016042;regulation of protein localization to membrane#GO:1905475;cellular process#GO:0009987;negative regulation of protein transport#GO:0051224;biological regulation#GO:0065007;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;negative regulation of transport#GO:0051051;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 lipase#PC00143;phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000014577.3|UniProtKB=A0A5F8HGT2 A0A5F8HGT2 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000016724.4|UniProtKB=F7BZ68 F7BZ68 RHOT2 PTHR24072:SF311 RHO FAMILY GTPASE MITOCHONDRIAL RHO GTPASE 2 ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265 supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;localization#GO:0051179;actin filament-based process#GO:0030029;organelle localization#GO:0051640;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;actin cytoskeleton organization#GO:0030036;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;mitochondrion localization#GO:0051646;actin filament organization#GO:0007015;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;apoptotic signaling pathway#GO:0097190;transport#GO:0006810;intracellular transport#GO:0046907;biological regulation#GO:0065007;regulation of mitochondrial membrane permeability#GO:0046902;cytoskeleton-dependent intracellular transport#GO:0030705;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;signaling#GO:0023052;establishment of organelle localization#GO:0051656;response to stimulus#GO:0050896;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;organelle transport along microtubule#GO:0072384;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;cytoskeleton organization#GO:0007010;regulation of membrane permeability#GO:0090559;cellular process#GO:0009987;signal transduction#GO:0007165;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996 mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;cell periphery#GO:0071944;organelle outer membrane#GO:0031968;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000027875.2|UniProtKB=K7E0Q3 K7E0Q3 TSTD3 PTHR44086:SF15 THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transferase#PC00220 MONDO|Ensembl=ENSMODG00000006199.3|UniProtKB=A0A5F8HLB3 A0A5F8HLB3 TIMP4 PTHR11844:SF26 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 4 molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;response to hormone#GO:0009725;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of protein catabolic process#GO:0042177;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162;regulation of catabolic process#GO:0009894;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;response to peptide#GO:1901652;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000029273.2|UniProtKB=A0A5F8GCI7 A0A5F8GCI7 PTHR24100:SF106 BUTYROPHILIN HERV-H LTR-ASSOCIATING PROTEIN 2 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune system process#GO:0002376 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000046068.1|UniProtKB=A0A5F8GKK6 A0A5F8GKK6 PTHR26454:SF43 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020598.4|UniProtKB=F6ZBY7 F6ZBY7 GABRA2 PTHR18945:SF218 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-2 transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075 multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;anatomical structure development#GO:0048856;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;localization#GO:0051179;system development#GO:0048731;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;cellular component assembly#GO:0022607;nervous system development#GO:0007399;chloride transport#GO:0006821;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789;synapse assembly#GO:0007416;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cell projection membrane#GO:0031253;dendrite#GO:0030425;leading edge membrane#GO:0031256;dendritic tree#GO:0097447;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;postsynapse#GO:0098794;cell junction#GO:0030054;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000038212.1|UniProtKB=A0A5F8HH21 A0A5F8HH21 PTHR12560:SF6 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000018569.4|UniProtKB=F7FRN0 F7FRN0 ESYT3 PTHR45761:SF4 EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C EXTENDED SYNAPTOTAGMIN-3 calcium ion binding#GO:0005509;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;lipid binding#GO:0008289;metal ion binding#GO:0046872;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylcholine binding#GO:0031210 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000006360.4|UniProtKB=A0A5F8GCP6 A0A5F8GCP6 QSOX1 PTHR22897:SF6 QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE SULFHYDRYL OXIDASE 1 catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;intramolecular oxidoreductase activity#GO:0016860;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;disulfide oxidoreductase activity#GO:0015036;isomerase activity#GO:0016853;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;protein-disulfide reductase activity#GO:0015035 protein folding#GO:0006457;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;extracellular structure organization#GO:0043062;biosynthetic process#GO:0009058;gene expression#GO:0010467;extracellular matrix assembly#GO:0085029;protein maturation#GO:0051604;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 oxidase#PC00175;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000029158.2|UniProtKB=K7DZQ1 K7DZQ1 U2AF1 PTHR12620:SF11 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT SPLICING FACTOR U2AF 35 KDA SUBUNIT binding#GO:0005488;nucleic acid binding#GO:0003676;pre-mRNA binding#GO:0036002;RNA binding#GO:0003723 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000008340.3|UniProtKB=A0A5F8GMR4 A0A5F8GMR4 RNF157 PTHR22996:SF1 MAHOGUNIN E3 UBIQUITIN LIGASE RNF157 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000042746.1|UniProtKB=A0A5F8G6T7 A0A5F8G6T7 RNF227 PTHR22791:SF14 RING-TYPE DOMAIN-CONTAINING PROTEIN RING FINGER PROTEIN 227 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000037544.1|UniProtKB=A0A5F8HEW8 A0A5F8HEW8 FAH PTHR43069:SF2 FUMARYLACETOACETASE FUMARYLACETOACETASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;proteinogenic amino acid metabolic process#GO:0170039;phenol-containing compound metabolic process#GO:0018958;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 MONDO|Ensembl=ENSMODG00000037255.1|UniProtKB=A0A5F8H759 A0A5F8H759 LOC100020384 PTHR13976:SF36 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H3 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000013683.4|UniProtKB=F6QPU7 F6QPU7 PTHR22997:SF0 PIH1 DOMAIN-CONTAINING PROTEIN 1 PIH1 DOMAIN-CONTAINING PROTEIN 1 nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000008503.4|UniProtKB=F7FTG1 F7FTG1 SST PTHR10558:SF2 SOMATOSTATIN SOMATOSTATIN hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;peptide hormone#PC00179 MONDO|Ensembl=ENSMODG00000012307.3|UniProtKB=A0A5F8GZR4 A0A5F8GZR4 PGRMC2 PTHR10281:SF24 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT 2 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003616.4|UniProtKB=A0A5F8H5A2 A0A5F8H5A2 REPIN1 PTHR24406:SF11 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED DNA-BINDING PROTEIN REPIN1 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000003066.3|UniProtKB=F6PNN7 F6PNN7 PTHR15441:SF2 RIBONUCLEASE P PROTEIN SUBUNIT P14 RIBONUCLEASE P_MRP PROTEIN SUBUNIT POP5 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 intracellular membraneless organelle#GO:0043232;ribonuclease MRP complex#GO:0000172;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;endonuclease complex#GO:1905348;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;multimeric ribonuclease P complex#GO:0030681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonuclease P complex#GO:0030677;endoribonuclease complex#GO:1902555;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000011956.3|UniProtKB=F7CV01 F7CV01 TM2D3 PTHR21016:SF7 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 3 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of Notch signaling pathway#GO:0045747;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;cell communication#GO:0007154;positive regulation of signaling#GO:0023056 MONDO|Ensembl=ENSMODG00000004351.3|UniProtKB=F6WQJ6 F6WQJ6 PTHR23036:SF17 CYTOKINE RECEPTOR INTERLEUKIN-5 RECEPTOR SUBUNIT ALPHA transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375 cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 MONDO|Ensembl=ENSMODG00000009341.4|UniProtKB=F7GAP1 F7GAP1 PTHR37336:SF1 SIMILAR TO 9930012K11RIK PROTEIN SIMILAR TO HUMAN CHROMOSOME 8 OPEN READING FRAME 58 MONDO|Ensembl=ENSMODG00000009222.2|UniProtKB=A0A5F8GXZ9 A0A5F8GXZ9 PTHR23048:SF66 MYOSIN LIGHT CHAIN 1, 3 CALMODULIN 2 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000037234.1|UniProtKB=A0A5F8GW73 A0A5F8GW73 SPP1 PTHR10607:SF1 OSTEOPONTIN OSTEOPONTIN signaling receptor binding#GO:0005102;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877 anatomical structure development#GO:0048856;animal organ development#GO:0048513;bone mineralization#GO:0030282;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;biomineral tissue development#GO:0031214;cell adhesion#GO:0007155;ossification#GO:0001503;tissue development#GO:0009888;multicellular organismal process#GO:0032501;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000012800.3|UniProtKB=F7DZ71 F7DZ71 PTHR24363:SF5 SERINE/THREONINE PROTEIN KINASE SERINE_THREONINE KINASE-LIKE DOMAIN-CONTAINING PROTEIN STKLD1 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000011310.4|UniProtKB=F6WJD4 F6WJD4 MED8 PTHR13074:SF9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000014445.3|UniProtKB=F7ATY2 F7ATY2 WDTC1 PTHR15574:SF40 WD REPEAT DOMAIN-CONTAINING FAMILY WD AND TETRATRICOPEPTIDE REPEATS PROTEIN 1 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of lipid biosynthetic process#GO:0046890;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of lipid metabolic process#GO:0019216 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000002371.3|UniProtKB=F7GD97 F7GD97 CMBL PTHR46812:SF1 CARBOXYMETHYLENEBUTENOLIDASE HOMOLOG CARBOXYMETHYLENEBUTENOLIDASE HOMOLOG MONDO|Ensembl=ENSMODG00000007388.3|UniProtKB=F6ZMQ6 F6ZMQ6 LOC130453495 PTHR11334:SF60 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G-PROTEIN COUPLED RECEPTOR MEMBER H G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021011.4|UniProtKB=F6QZT0 F6QZT0 ATP5PF PTHR12441:SF10 ATP SYNTHASE COUPLING FACTOR 6, MITOCHONDRIAL ATP SYNTHASE PERIPHERAL STALK SUBUNIT F6, MITOCHONDRIAL membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;proton-transporting ATP synthase complex#GO:0045259;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 primary active transporter#PC00068;ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000015095.4|UniProtKB=A0A5F8H8E9 A0A5F8H8E9 IL1RAP PTHR11890:SF20 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375 regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017175.4|UniProtKB=F6QCZ1 F6QCZ1 CCDC146 PTHR32083:SF34 CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 146 cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000007544.4|UniProtKB=F7GAU1 F7GAU1 TMEM9B PTHR13064:SF2 TRANSMEMBRANE PROTEIN 9 FAMILY MEMBER TRANSMEMBRANE PROTEIN 9B MONDO|Ensembl=ENSMODG00000024110.2|UniProtKB=F6WJQ2 F6WJQ2 CCDC70 PTHR21533:SF22 LEUCINE-RICH PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 70 MONDO|Ensembl=ENSMODG00000040965.1|UniProtKB=A0A5F8HIK5 A0A5F8HIK5 PTHR23239:SF120 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 27 structural molecule activity#GO:0005198 supramolecular fiber organization#GO:0097435;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;morphogenesis of an epithelium#GO:0002009;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;animal organ development#GO:0048513;developmental process#GO:0032502;epidermis development#GO:0008544;skin development#GO:0043588;cytoskeleton organization#GO:0007010;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;organelle organization#GO:0006996 supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000028941.2|UniProtKB=A0A5F8GHK1 A0A5F8GHK1 MYLK4 PTHR24347:SF379 SERINE/THREONINE-PROTEIN KINASE MYOSIN LIGHT CHAIN KINASE FAMILY MEMBER 4 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000001389.4|UniProtKB=F7BD45 F7BD45 MYH4 PTHR45615:SF79 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-4 isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;ATP-dependent activity#GO:0140657;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544 system process#GO:0003008;multicellular organismal process#GO:0032501;muscle contraction#GO:0006936;muscle system process#GO:0003012 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000020389.4|UniProtKB=F7C062 F7C062 RAD1 PTHR10870:SF0 CELL CYCLE CHECKPOINT PROTEIN RAD1 CELL CYCLE CHECKPOINT PROTEIN RAD1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;DNA integrity checkpoint signaling#GO:0031570;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;negative regulation of cell cycle#GO:0045786;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232 exodeoxyribonuclease#PC00098;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000020315.4|UniProtKB=A0A5F8HBY7 A0A5F8HBY7 RICTOR PTHR13298:SF11 CYTOSOLIC REGULATOR PIANISSIMO RAPAMYCIN-INSENSITIVE COMPANION OF MTOR protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;TORC2 signaling#GO:0038203;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;intracellular signal transduction#GO:0035556;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;TOR signaling#GO:0031929;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 TOR complex#GO:0038201;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000028688.2|UniProtKB=K7E609 K7E609 PTHR12015:SF170 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 5 binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cellular response to stimulus#GO:0051716;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;cell motility#GO:0048870;regulation of cellular process#GO:0050794;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cytokine-mediated signaling pathway#GO:0019221;cell chemotaxis#GO:0060326;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;regulation of cell motility#GO:2000145;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;cell migration#GO:0016477;regulation of cell migration#GO:0030334;leukocyte migration#GO:0050900;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;positive regulation of locomotion#GO:0040017;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of cell motility#GO:2000147;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;response to peptide#GO:1901652;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;taxis#GO:0042330;cell surface receptor signaling pathway#GO:0007166;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000004732.4|UniProtKB=F6Y191 F6Y191 CDH6 PTHR24027:SF322 CADHERIN-23 CADHERIN-6 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330;cell motility#GO:0048870;cell adhesion#GO:0007155;synapse organization#GO:0050808;anatomical structure development#GO:0048856;synaptic membrane adhesion#GO:0099560;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell migration#GO:0016477;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840 anchoring junction#GO:0070161;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000003830.4|UniProtKB=F7GJD7 F7GJD7 PCSK9 PTHR43806:SF60 PEPTIDASE S8 PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 9 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000001456.3|UniProtKB=A0A5F8H511 A0A5F8H511 QPRT PTHR32179:SF3 NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;oxoacid metabolic process#GO:0043436;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine-containing compound metabolic process#GO:0072524;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;carboxylic acid catabolic process#GO:0046395;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 MONDO|Ensembl=ENSMODG00000006007.4|UniProtKB=F6SKF7 F6SKF7 NSG2 PTHR28546:SF2 NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2-RELATED NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;biological regulation#GO:0065007;transport#GO:0006810;metabolic process#GO:0008152;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular protein localization#GO:0008104;protein transport#GO:0015031;regulation of biological quality#GO:0065008;localization#GO:0051179;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;cellular localization#GO:0051641 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;late endosome#GO:0005770;endomembrane system#GO:0012505;glutamatergic synapse#GO:0098978;synaptic membrane#GO:0097060;cell junction#GO:0030054;vesicle#GO:0031982;intracellular vesicle#GO:0097708;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;endosome#GO:0005768;postsynaptic membrane#GO:0045211;dendrite#GO:0030425;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000000048.4|UniProtKB=F6RF44 F6RF44 PTHR23120:SF3 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT FAMILY MEMBER 4 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000045399.1|UniProtKB=K7E4C7 K7E4C7 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000008501.4|UniProtKB=F7FTQ2 F7FTQ2 FBXO5 PTHR15493:SF8 F-BOX ONLY PROTEIN 5 AND 43 F-BOX ONLY PROTEIN 5 molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857 regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;regulation of meiotic cell cycle#GO:0051445;positive regulation of cell cycle process#GO:0090068;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cell cycle G1/S phase transition#GO:0044843;negative regulation of sister chromatid segregation#GO:0033046;negative regulation of cell cycle#GO:0045786;regulation of chromosome segregation#GO:0051983;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;G1/S transition of mitotic cell cycle#GO:0000082;negative regulation of chromosome segregation#GO:0051985;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of G2/M transition of mitotic cell cycle#GO:0010389;negative regulation of chromosome organization#GO:2001251;mitotic cell cycle phase transition#GO:0044772;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of reproductive process#GO:2000241;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;regulation of cell cycle G2/M phase transition#GO:1902749;positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047;regulation of mitotic nuclear division#GO:0007088;negative regulation of chromosome separation#GO:1905819;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000013581.4|UniProtKB=A0A5F8H7B5 A0A5F8H7B5 CUX1 PTHR14043:SF4 CCAAT DISPLACEMENT PROTEIN-RELATED HOMEOBOX PROTEIN CUT-LIKE 1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000046641.1|UniProtKB=A0A5F8H486 A0A5F8H486 PTHR26453:SF17 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040391.1|UniProtKB=K7E5J4 K7E5J4 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000008622.4|UniProtKB=F6PH08 F6PH08 SHISA2 PTHR31395:SF0 SHISA PROTEIN SHISA-2 HOMOLOG negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000051000.1|UniProtKB=A0A5F8H490 A0A5F8H490 MCEE PTHR43048:SF3 METHYLMALONYL-COA EPIMERASE METHYLMALONYL-COA EPIMERASE, MITOCHONDRIAL racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;isomerase activity#GO:0016853 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521 isomerase#PC00135;epimerase/racemase#PC00096 Methylmalonyl pathway#P02755>Methylmalonyl-CoA epimerase#P03032 MONDO|Ensembl=ENSMODG00000007567.3|UniProtKB=F7FZW1 F7FZW1 LOC100029165 PTHR24242:SF183 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11G2 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000044619.1|UniProtKB=A0A5F8HDP9 A0A5F8HDP9 LOC100013915 PTHR23430:SF72 HISTONE H2A HISTONE H2A TYPE 2-B structural molecule activity#GO:0005198 negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892 organelle#GO:0043226;protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000005850.4|UniProtKB=F6TKY5 F6TKY5 PTHR18945:SF397 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT EPSILON transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;neurotransmitter receptor activity#GO:0030594;ligand-gated channel activity#GO:0022834;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transmembrane signaling receptor activity#GO:0004888;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267;molecular transducer activity#GO:0060089 chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;system development#GO:0048731;anatomical structure development#GO:0048856;chloride transmembrane transport#GO:1902476;localization#GO:0051179;cell communication#GO:0007154;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;signaling#GO:0023052;synapse assembly#GO:0007416;animal gross anatomical part developmental process#GO:0160108;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;cellular process#GO:0009987;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;monoatomic anion transmembrane transport#GO:0098656;cellular component assembly#GO:0022607;chloride transport#GO:0006821;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 leading edge membrane#GO:0031256;dendritic tree#GO:0097447;dendrite#GO:0030425;cell projection membrane#GO:0031253;postsynapse#GO:0098794;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;neuron projection membrane#GO:0032589;cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000024058.2|UniProtKB=F7DF88 F7DF88 ATXN7L3 PTHR46367:SF1 ATAXIN-7-LIKE PROTEIN 3 ATAXIN-7-LIKE PROTEIN 3 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;SAGA complex#GO:0000124;DUBm complex#GO:0071819;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000001335.4|UniProtKB=F7FWC9 F7FWC9 TMCO1 PTHR20917:SF1 PNAS-RELATED CALCIUM LOAD-ACTIVATED CALCIUM CHANNEL monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262;calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000038666.1|UniProtKB=A0A5F8GYK9 A0A5F8GYK9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000018460.3|UniProtKB=F7CU36 F7CU36 PTHR21191:SF8 AQUAPORIN AQUAPORIN-12A-RELATED passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;channel activity#GO:0015267 chemical homeostasis#GO:0048878;regulation of anatomical structure size#GO:0090066;regulation of biological quality#GO:0065008;regulation of cell size#GO:0008361;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;biological regulation#GO:0065007;homeostatic process#GO:0042592 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000006620.5|UniProtKB=F7GEQ7 F7GEQ7 ZNF219 PTHR45925:SF1 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 219 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000043526.1|UniProtKB=A0A5F8HBZ5 A0A5F8HBZ5 JKAMP PTHR12740:SF4 JNK1/MAPK8-ASSOCIATED MEMBRANE PROTEIN JNK1_MAPK8-ASSOCIATED MEMBRANE PROTEIN enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014688.3|UniProtKB=F7DNK8 F7DNK8 PTHR24250:SF65 CHYMOTRYPSIN-RELATED CHYMOTRYPSINOGEN B catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000042301.1|UniProtKB=A0A5F8HFP5 A0A5F8HFP5 PTHR17453:SF0 SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein targeting#GO:0006605;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;establishment of protein localization to endoplasmic reticulum#GO:0072599;cellular component assembly#GO:0022607 signal recognition particle, endoplasmic reticulum targeting#GO:0005786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribonucleoprotein complex#GO:1990904 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000009669.3|UniProtKB=F6SHQ8 F6SHQ8 KERA PTHR45712:SF13 AGAP008170-PA KERATOCAN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000006021.3|UniProtKB=F7AJ77 F7AJ77 PTHR22811:SF50 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;Golgi organization#GO:0007030;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737 membrane traffic protein#PC00150;vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000017848.4|UniProtKB=A0A5F8GB57 A0A5F8GB57 TRAPPC3 PTHR13048:SF2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;cis-Golgi network#GO:0005801;vesicle tethering complex#GO:0099023;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;bounding membrane of organelle#GO:0098588;cytosol#GO:0005829;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;TRAPP complex#GO:0030008 MONDO|Ensembl=ENSMODG00000015803.3|UniProtKB=F7FRZ2 F7FRZ2 ADGRF3 PTHR45813:SF2 IG-LIKE DOMAIN-CONTAINING PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR F3 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000006000.3|UniProtKB=A0A5F8GUV4 A0A5F8GUV4 HRH1 PTHR24247:SF223 5-HYDROXYTRYPTAMINE RECEPTOR HISTAMINE H1 RECEPTOR molecular transducer activity#GO:0060089;acetylcholine receptor activity#GO:0015464;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;response to chemical#GO:0042221;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell junction#GO:0030054;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Histamine H1 receptor mediated signaling pathway#P04385>H1#P04485;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 MONDO|Ensembl=ENSMODG00000008794.4|UniProtKB=F6QVI9 F6QVI9 SLTM PTHR15683:SF5 SCAFFOLD ATTACHMENT FACTOR B-RELATED SAFB-LIKE TRANSCRIPTION MODULATOR organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000007697.3|UniProtKB=F7F9S0 F7F9S0 PTHR10366:SF241 NAD DEPENDENT EPIMERASE/DEHYDRATASE SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E MEMBER 2-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 dehydratase#PC00091;lyase#PC00144;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000016265.3|UniProtKB=F7BHD9 F7BHD9 SLITRK3 PTHR45773:SF6 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 3 animal gross anatomical part developmental process#GO:0160108;regulation of synapse organization#GO:0050807;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular component biogenesis#GO:0044089;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;regulation of cell junction assembly#GO:1901888;regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of synapse assembly#GO:0051965;axon development#GO:0061564;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054;postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;GABA-ergic synapse#GO:0098982;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000051385.1|UniProtKB=A0A5F8HHJ0 A0A5F8HHJ0 SLC22A12 PTHR24064:SF205 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 12 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000001775.4|UniProtKB=F6WJB1 F6WJB1 STX1B PTHR19957:SF334 SYNTAXIN SYNTAXIN-1B protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;secretion by cell#GO:0032940;protein transport#GO:0015031;vesicle fusion#GO:0006906;export from cell#GO:0140352;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;exocytosis#GO:0006887;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;SNARE complex#GO:0031201;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 MONDO|Ensembl=ENSMODG00000024992.1|UniProtKB=F6TUR3 F6TUR3 LOC100020439 PTHR11937:SF414 ACTIN ACTIN, CYTOPLASMIC 1 structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;anatomical structure development#GO:0048856;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 cytoskeleton#GO:0005856;transferase complex#GO:1990234;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular protein-containing complex#GO:0140535;membrane#GO:0016020;H4 histone acetyltransferase complex#GO:1902562;axon#GO:0030424;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;plasma membrane bounded cell projection#GO:0120025;actin filament#GO:0005884;cell junction#GO:0030054;histone acetyltransferase complex#GO:0000123;chromatin#GO:0000785;neuron projection#GO:0043005;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;NuA4 histone acetyltransferase complex#GO:0035267;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;acetyltransferase complex#GO:1902493;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995 actin and actin related protein#PC00039 Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470 MONDO|Ensembl=ENSMODG00000040905.1|UniProtKB=A0A5F8H410 A0A5F8H410 RGS13 PTHR10845:SF32 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 13 GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 MONDO|Ensembl=ENSMODG00000006146.3|UniProtKB=F7BSU8 F7BSU8 STC2 PTHR11245:SF2 STANNIOCALCIN STANNIOCALCIN-2 cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion homeostasis#GO:0055074;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 MONDO|Ensembl=ENSMODG00000008851.4|UniProtKB=A0A5F8GGD5 A0A5F8GGD5 TAZ PTHR12497:SF8 TAZ PROTEIN TAFAZZIN TAFAZZIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycerolipid metabolic process#GO:0046486;phosphatidylglycerol metabolic process#GO:0046471;phospholipid metabolic process#GO:0006644;cellular component organization#GO:0016043;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;organelle organization#GO:0006996;organophosphate metabolic process#GO:0019637;mitochondrial membrane organization#GO:0007006;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000013761.5|UniProtKB=F6UBA4 F6UBA4 BAZ1B PTHR46802:SF1 TYROSINE-PROTEIN KINASE BAZ1B TYROSINE-PROTEIN KINASE BAZ1B histone binding#GO:0042393;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone kinase activity#GO:0035173;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;protein kinase activity#GO:0004672;histone modifying activity#GO:0140993;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular component organization#GO:0016043;response to stress#GO:0006950 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;ISWI-type complex#GO:0031010;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 protein modifying enzyme#PC00260;non-receptor tyrosine protein kinase#PC00168 MONDO|Ensembl=ENSMODG00000002127.4|UniProtKB=F6U0V5 F6U0V5 ENPP7 PTHR10151:SF63 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 7 hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;lipase activity#GO:0016298;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081 cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;sphingomyelin metabolic process#GO:0006684;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;microvillus#GO:0005902;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;membrane#GO:0016020 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000020328.4|UniProtKB=F7G7B2 F7G7B2 MS4A13 PTHR23320:SF42 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 13 transporter#PC00227 MONDO|Ensembl=ENSMODG00000005120.4|UniProtKB=F7F5S5 F7F5S5 SHFL PTHR16135:SF2 REPRESSOR OF YIELD OF DENV PROTEIN SHIFTLESS ANTIVIRAL INHIBITOR OF RIBOSOMAL FRAMESHIFTING PROTEIN ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 immune system process#GO:0002376;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542 MONDO|Ensembl=ENSMODG00000003397.4|UniProtKB=K7E4N3 K7E4N3 RNF31 PTHR16004:SF5 RING FINGER PROTEIN 31-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF31 modification-dependent protein binding#GO:0140030;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;polyubiquitin modification-dependent protein binding#GO:0031593;catalytic activity#GO:0003824;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;ubiquitin binding#GO:0043130;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000016708.1|UniProtKB=F7D1U8 F7D1U8 MCRIP2 PTHR48614:SF1 AT03386P MAPK REGULATED COREPRESSOR INTERACTING PROTEIN 2 MONDO|Ensembl=ENSMODG00000011150.4|UniProtKB=F7BY71 F7BY71 PTHR14224:SF9 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 14 MONDO|Ensembl=ENSMODG00000000327.4|UniProtKB=F6VTP9 F6VTP9 LOC100013114 PTHR24302:SF42 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 FAMILY 3 SUBFAMILY A MEMBER 4 steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000013288.4|UniProtKB=F6ZKA9 F6ZKA9 LAMB2 PTHR10574:SF36 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-2 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 plasma membrane bounded cell projection morphogenesis#GO:0120039;substrate adhesion-dependent cell spreading#GO:0034446;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular component assembly#GO:0022607;generation of neurons#GO:0048699;cell adhesion#GO:0007155;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;axon development#GO:0061564;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;tissue development#GO:0009888;extracellular matrix assembly#GO:0085029;multicellular organismal process#GO:0032501;cell migration#GO:0016477;external encapsulating structure organization#GO:0045229;system development#GO:0048731;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;cell-substrate adhesion#GO:0031589;cell motility#GO:0048870 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;basement membrane#GO:0005604;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 MONDO|Ensembl=ENSMODG00000003192.4|UniProtKB=F6VGQ5 F6VGQ5 CDC16 PTHR12558:SF9 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 16 HOMOLOG enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein modification by small protein conjugation or removal#GO:0070647;positive regulation of cellular component organization#GO:0051130;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;modification-dependent macromolecule catabolic process#GO:0043632;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of organelle organization#GO:0010638;protein modification by small protein conjugation#GO:0032446;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of chromosome segregation#GO:0051983;positive regulation of mitotic nuclear division#GO:0045840;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of chromosome separation#GO:1905818;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;proteasomal protein catabolic process#GO:0010498;positive regulation of cell cycle#GO:0045787;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;cell division#GO:0051301;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of chromosome organization#GO:0033044;macromolecule metabolic process#GO:0043170;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of mitotic cell cycle#GO:0045931;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of nuclear division#GO:0051783 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000002026.4|UniProtKB=F6QX21 F6QX21 SCG3 PTHR17388:SF2 SECRETOGRANIN III SECRETOGRANIN-3 macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179 membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000047877.1|UniProtKB=A0A5F8G483 A0A5F8G483 PTHR11588:SF239 TUBULIN TUBULIN ALPHA CHAIN structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001 mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 tubulin#PC00228;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000038324.1|UniProtKB=A0A5F8GK73 A0A5F8GK73 PTHR45986:SF1 ZINC FINGER MATRIN-TYPE PROTEIN 2 ZINC FINGER MATRIN-TYPE PROTEIN 2 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398 intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000009884.3|UniProtKB=F6VD16 F6VD16 SLC6A4 PTHR11616:SF105 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT SEROTONIN TRANSPORTER secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;heterocyclic compound binding#GO:1901363;metal ion transmembrane transporter activity#GO:0046873;binding#GO:0005488;symporter activity#GO:0015293;serotonin binding#GO:0051378;monoatomic cation transmembrane transporter activity#GO:0008324;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;small molecule binding#GO:0036094;ion binding#GO:0043167;solute:sodium symporter activity#GO:0015370;cation binding#GO:0043169 establishment of localization#GO:0051234;import into cell#GO:0098657;amino acid transport#GO:0006865;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;neurotransmitter transport#GO:0006836;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;sodium ion transmembrane transport#GO:0035725;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;organic hydroxy compound transport#GO:0015850;metal ion transport#GO:0030001;sodium ion transport#GO:0006814 synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cell junction#GO:0030054 primary active transporter#PC00068 5HT3 type receptor mediated signaling pathway#P04375>5HT transporter#P04421;5HT2 type receptor mediated signaling pathway#P04374>5HT transporter#P04417;5HT1 type receptor mediated signaling pathway#P04373>5HT transporter#P04409;5HT4 type receptor mediated signaling pathway#P04376>5HT transporter#P04431 MONDO|Ensembl=ENSMODG00000040704.1|UniProtKB=F7BFX0 F7BFX0 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000018837.2|UniProtKB=F7GKA8 F7GKA8 LOC130456272 PTHR45831:SF3 LD24721P SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN ALPHA localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000020614.4|UniProtKB=F6ZB46 F6ZB46 PTHR18945:SF571 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3 ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;neurotransmitter receptor activity#GO:0030594;chloride channel activity#GO:0005254;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 synaptic signaling#GO:0099536;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;GABA-ergic synapse#GO:0098982;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;postsynaptic membrane#GO:0045211;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000024716.2|UniProtKB=F7FBT8 F7FBT8 PTHR45752:SF35 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 30 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017952.2|UniProtKB=F7E3B7 F7E3B7 GJA4 PTHR11984:SF54 CONNEXIN GAP JUNCTION ALPHA-4 PROTEIN passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267 regulation of biological process#GO:0050789;cellular process#GO:0009987;cell communication#GO:0007154;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796 gap junction#PC00105;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000017112.4|UniProtKB=F7B5C7 F7B5C7 EFNA3 PTHR11304:SF5 EPHRIN EPHRIN-A3 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 intercellular signal molecule#PC00207;membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000009271.5|UniProtKB=H9H6B1 H9H6B1 ATN1 PTHR13859:SF9 ATROPHIN-RELATED ATROPHIN-1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000020909.5|UniProtKB=A0A5F8HIN4 A0A5F8HIN4 CACNA1G PTHR10037:SF137 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1G voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated sodium channel activity#GO:0005248;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843 regulation of secretion#GO:0051046;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of exocytosis#GO:0017157;calcium ion import#GO:0070509;regulation of cellular process#GO:0050794;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;positive regulation of cytosolic calcium ion concentration#GO:0007204;positive regulation of secretion#GO:0051047;transmembrane transport#GO:0055085;regulation of secretion by cell#GO:1903530;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;calcium ion transmembrane transport#GO:0070588;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;action potential#GO:0001508;calcium ion transmembrane import into cytosol#GO:0097553;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular process#GO:0009987;positive regulation of secretion by cell#GO:1903532;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;monoatomic cation transmembrane transport#GO:0098655 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706 voltage-gated ion channel#PC00241 Endogenous cannabinoid signaling#P05730>Ca2+ channel#P05750;GABA-B receptor II signaling#P05731>Ca channel#P05753;Nicotine pharmacodynamics pathway#P06587>CACNA#P06600 MONDO|Ensembl=ENSMODG00000017941.4|UniProtKB=F7E3S1 F7E3S1 ARHGDIB PTHR10980:SF15 RHO GDP-DISSOCIATION INHIBITOR RHO GDP-DISSOCIATION INHIBITOR 2 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;membrane#GO:0016020 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000025453.3|UniProtKB=A0A5F8GJ17 A0A5F8GJ17 TOM1 PTHR13856:SF32 VHS DOMAIN CONTAINING PROTEIN FAMILY TARGET OF MYB1 MEMBRANE TRAFFICKING PROTEIN protein binding#GO:0005515;binding#GO:0005488;clathrin binding#GO:0030276 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 MONDO|Ensembl=ENSMODG00000039074.1|UniProtKB=A0A5F8GZT0 A0A5F8GZT0 MYF6 PTHR11534:SF4 MYOGENIC FACTOR MYOGENIC FACTOR 6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;regulation of developmental process#GO:0050793;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;skeletal muscle tissue development#GO:0007519;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;animal organ development#GO:0048513;muscle organ development#GO:0007517;striated muscle tissue development#GO:0014706;positive regulation of cell differentiation#GO:0045597 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000050604.1|UniProtKB=A0A5F8GBB1 A0A5F8GBB1 LOC100013669 PTHR23430:SF42 HISTONE H2A HISTONE H2A TYPE 2-A structural molecule activity#GO:0005198 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000010825.3|UniProtKB=F7BE62 F7BE62 SYN1 PTHR10841:SF24 SYNAPSIN SYNAPSIN-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cytoskeletal adaptor activity#GO:0008093 cellular component organization#GO:0016043;cell junction organization#GO:0034330;organelle localization#GO:0051640;synapse organization#GO:0050808;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840 transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;presynapse#GO:0098793;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synapsin#P05775 MONDO|Ensembl=ENSMODG00000001530.4|UniProtKB=A0A5F8G5I0 A0A5F8G5I0 STX18 PTHR15959:SF0 SYNTAXIN-18 SYNTAXIN-18 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;membrane protein complex#GO:0098796 membrane traffic protein#PC00150;SNARE protein#PC00034 MONDO|Ensembl=ENSMODG00000047141.1|UniProtKB=A0A5F8HBR7 A0A5F8HBR7 PTHR33064:SF44 POL PROTEIN RIBONUCLEASE H MONDO|Ensembl=ENSMODG00000010954.3|UniProtKB=F7BCD4 F7BCD4 PTHR18884:SF54 SEPTIN SEPTIN-8 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 macromolecule localization#GO:0033036;cell cycle#GO:0007049;cell division#GO:0051301;cellular process#GO:0009987;cell cycle process#GO:0022402;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;intracellular protein localization#GO:0008104 cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000036597.1|UniProtKB=A0A5F8GYH2 A0A5F8GYH2 PTHR23262:SF50 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-8 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000038447.1|UniProtKB=A0A5F8GKZ8 A0A5F8GKZ8 RGS19 PTHR10845:SF145 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 19 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 MONDO|Ensembl=ENSMODG00000003940.4|UniProtKB=F7G9R3 F7G9R3 PPP4R2 PTHR16487:SF0 PPP4R2-RELATED PROTEIN SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2 molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000004163.4|UniProtKB=F6QPZ5 F6QPZ5 ESRRG PTHR48092:SF10 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN-RELATED RECEPTOR GAMMA signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000020706.4|UniProtKB=F7BB01 F7BB01 IGFBP7 PTHR14186:SF19 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 7 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 tube development#GO:0035295;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;system development#GO:0048731;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000018171.4|UniProtKB=F7BU27 F7BU27 C1R PTHR24255:SF25 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED COMPLEMENT C1R SUBCOMPONENT peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 zymogen activation#GO:0031638;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000001220.4|UniProtKB=A0A5F8GXA8 A0A5F8GXA8 GSTK1 PTHR42943:SF2 GLUTATHIONE S-TRANSFERASE KAPPA GLUTATHIONE S-TRANSFERASE KAPPA 1 transferase#PC00220 MONDO|Ensembl=ENSMODG00000003059.4|UniProtKB=F6PNU8 F6PNU8 SLC25A33 PTHR45829:SF5 MITOCHONDRIAL CARRIER PROTEIN RIM2 SOLUTE CARRIER FAMILY 25 MEMBER 33 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000017613.4|UniProtKB=A0A5F8G5X2 A0A5F8G5X2 ARHGAP5 PTHR46005:SF2 RHO GTPASE-ACTIVATING PROTEIN 190 RHO GTPASE-ACTIVATING PROTEIN 5 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of cell projection organization#GO:0031344;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;regulation of axonogenesis#GO:0050770;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;cellular process#GO:0009987;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;regulation of cell size#GO:0008361;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;cellular response to stimulus#GO:0051716;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GTPase-activating protein#PC00257;G-protein modulator#PC00022 PDGF signaling pathway#P00047>Rho#P01174 MONDO|Ensembl=ENSMODG00000001501.4|UniProtKB=A0A5F8G6J4 A0A5F8G6J4 CNBD2 PTHR23011:SF43 CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN 2 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 spermatogenesis#GO:0007283;developmental process#GO:0032502;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;male gamete generation#GO:0048232;gamete generation#GO:0007276 MONDO|Ensembl=ENSMODG00000013672.3|UniProtKB=F6TX86 F6TX86 SIVA1 PTHR14365:SF1 APOPTOSIS REGULATORY PROTEIN SIVA APOPTOSIS REGULATORY PROTEIN SIVA T cell receptor signaling pathway#GO:0050852;negative regulation of cellular process#GO:0048523;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;apoptotic signaling pathway#GO:0097190;multicellular organismal-level homeostasis#GO:0048871;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;homeostasis of number of cells#GO:0048872;regulation of immune response#GO:0050776;cell communication#GO:0007154;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;homeostatic process#GO:0042592;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;lymphocyte homeostasis#GO:0002260;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;antigen receptor-mediated signaling pathway#GO:0050851;negative regulation of signal transduction#GO:0009968;immune system process#GO:0002376;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;apoptotic process#GO:0006915;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;signaling#GO:0023052 MONDO|Ensembl=ENSMODG00000046566.1|UniProtKB=F6ZQ09 F6ZQ09 LOC100016722 PTHR48018:SF172 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8G3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009924.4|UniProtKB=A0A5F8HK74 A0A5F8HK74 NEO1 PTHR10075:SF124 BASIGIN RELATED NEOGENIN cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000015669.3|UniProtKB=F7EI53 F7EI53 EIF2B4 PTHR10233:SF14 TRANSLATION INITIATION FACTOR EIF-2B TRANSLATION INITIATION FACTOR EIF2B SUBUNIT DELTA translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045 translation factor#PC00223;translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000037882.1|UniProtKB=A0A5F8H3X0 A0A5F8H3X0 PTHR45740:SF6 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP12 pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000049813.1|UniProtKB=A0A5F8G342 A0A5F8G342 PTHR11753:SF58 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP COMPLEX MU_SIGMA SUBUNIT DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150;vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000049520.1|UniProtKB=A0A5F8GRG6 A0A5F8GRG6 PTHR47193:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 1 voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215 calcium ion transport#GO:0006816;microtubule-based process#GO:0007017;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cilium-dependent cell motility#GO:0060285;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;gamete generation#GO:0007276;regulation of microtubule-based movement#GO:0060632;sperm motility#GO:0097722;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;transport#GO:0006810;spermatogenesis#GO:0007283;developmental process#GO:0032502;flagellated sperm motility#GO:0030317;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;male gamete generation#GO:0048232;multicellular organismal reproductive process#GO:0048609;regulation of cell motility#GO:2000145;localization#GO:0051179;monoatomic cation transport#GO:0006812;sexual reproduction#GO:0019953;regulation of microtubule-based process#GO:0032886;reproductive process#GO:0022414;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;cell motility#GO:0048870;microtubule-based movement#GO:0007018;developmental process involved in reproduction#GO:0003006 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;plasma membrane#GO:0005886;CatSper complex#GO:0036128;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;calcium channel complex#GO:0034704;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000009242.5|UniProtKB=F7DWD2 F7DWD2 KIF23 PTHR24115:SF600 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF23 ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853 spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;chromosome segregation#GO:0007059;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;spindle assembly#GO:0051225;mitotic spindle assembly#GO:0090307;cellular process#GO:0009987;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;microtubule-based movement#GO:0007018;cell cycle#GO:0007049;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;microtubule cytoskeleton organization involved in mitosis#GO:1902850;membraneless organelle assembly#GO:0140694;nuclear chromosome segregation#GO:0098813;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000001072.4|UniProtKB=F6YQG4 F6YQG4 PDE4B PTHR11347:SF108 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 4B hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 phosphodiesterase#PC00185;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000037095.1|UniProtKB=A0A5F8H9Z2 A0A5F8H9Z2 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000018399.4|UniProtKB=A0A5F8G3Y4 A0A5F8G3Y4 PTHR12316:SF24 NINJURIN-RELATED NINJURIN-2 protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632;binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839 programmed cell death#GO:0012501;cell death#GO:0008219;cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000004845.4|UniProtKB=A0A5F8H9P9 A0A5F8H9P9 SORBS2 PTHR14167:SF56 SH3 DOMAIN-CONTAINING SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell surface receptor signaling pathway#GO:0007166;Notch signaling pathway#GO:0007219;cell communication#GO:0007154;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010 dendritic tree#GO:0097447;dendrite#GO:0030425;cell junction#GO:0030054;cell body#GO:0044297;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;synapse#GO:0045202 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018197.4|UniProtKB=F7B6V6 F7B6V6 TIMMDC1 PTHR13002:SF1 C3ORF1 PROTEIN-RELATED COMPLEX I ASSEMBLY FACTOR TIMMDC1, MITOCHONDRIAL intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000016133.4|UniProtKB=A0A5F8GJX4 A0A5F8GJX4 MECOM PTHR24393:SF69 ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE MECOM transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000000587.2|UniProtKB=A0A5F8HJA5 A0A5F8HJA5 PTHR46541:SF1 ZINC FINGER PROTEIN AEBP2 ZINC FINGER PROTEIN AEBP2 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;PcG protein complex#GO:0031519;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000013247.4|UniProtKB=A0A5F8GYK1 A0A5F8GYK1 PTHR34436:SF1 CENTROMERE PROTEIN M CENTROMERE PROTEIN M organelle#GO:0043226;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;kinetochore#GO:0000776;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000019585.4|UniProtKB=F6QM63 F6QM63 ELOVL7 PTHR11157:SF118 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 7 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000012053.4|UniProtKB=A0A5F8GEM9 A0A5F8GEM9 SEC31A PTHR13923:SF23 SEC31-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC31A cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;COPII-coated vesicle budding#GO:0090114;cellular component organization#GO:0016043 vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle coat#GO:0030120;cytoplasm#GO:0005737;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 membrane traffic protein#PC00150;vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000036610.1|UniProtKB=A0A5F8G6W9 A0A5F8G6W9 LOC100018127 PTHR26450:SF11 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008181.3|UniProtKB=F7E4W8 F7E4W8 NAA35 PTHR21373:SF1 GLUCOSE REPRESSIBLE PROTEIN MAK10 N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;transferase complex#GO:1990234;catalytic complex#GO:1902494 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000015923.2|UniProtKB=F6ZR11 F6ZR11 PLA2G2F PTHR11716:SF8 PHOSPHOLIPASE A2 FAMILY MEMBER GROUP IIF SECRETORY PHOSPHOLIPASE A2 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phospholipid binding#GO:0005543;cation binding#GO:0043169;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;ion binding#GO:0043167;lipase activity#GO:0016298;small molecule binding#GO:0036094;A2-type glycerophospholipase activity#GO:0004623;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;lipid binding#GO:0008289;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488 regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;regulation of T cell activation#GO:0050863;negative regulation of cell-cell adhesion#GO:0022408;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;regulation of mononuclear cell proliferation#GO:0032944;negative regulation of T cell proliferation#GO:0042130;regulation of leukocyte proliferation#GO:0070663;metabolic process#GO:0008152;regulation of lymphocyte activation#GO:0051249;glycerolipid metabolic process#GO:0046486;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;negative regulation of cell adhesion#GO:0007162;negative regulation of cell population proliferation#GO:0008285;organophosphate metabolic process#GO:0019637;negative regulation of cell activation#GO:0050866;lipid metabolic process#GO:0006629;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;phospholipid metabolic process#GO:0006644;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of T cell proliferation#GO:0042129;phosphatidylglycerol metabolic process#GO:0046471;primary metabolic process#GO:0044238;negative regulation of multicellular organismal process#GO:0051241;regulation of cell population proliferation#GO:0042127;negative regulation of T cell activation#GO:0050868 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000003549.4|UniProtKB=F7GBJ9 F7GBJ9 TESMIN PTHR12446:SF22 TESMIN/TSO1-RELATED TESMIN regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000001625.4|UniProtKB=F7ANA6 F7ANA6 TADA1 PTHR21277:SF5 TRANSCRIPTIONAL ADAPTER 1 TRANSCRIPTIONAL ADAPTER 1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;SAGA-type complex#GO:0070461;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124 MONDO|Ensembl=ENSMODG00000015229.2|UniProtKB=F6V2X8 F6V2X8 ARF5 PTHR11711:SF30 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 5 heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;guanyl nucleotide binding#GO:0019001 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein#PC00020 Integrin signalling pathway#P00034>Arf1#P00923;Huntington disease#P00029>ARF#P00786 MONDO|Ensembl=ENSMODG00000048797.1|UniProtKB=A0A5F8GZU2 A0A5F8GZU2 PTHR26453:SF303 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2Y1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045124.1|UniProtKB=K7E412 K7E412 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000017887.4|UniProtKB=A0A5F8G7Z7 A0A5F8G7Z7 TUBE1 PTHR11588:SF13 TUBULIN TUBULIN EPSILON CHAIN nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 tubulin#PC00228;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000019185.4|UniProtKB=A0A5F8GJD1 A0A5F8GJD1 ZNF207 PTHR23215:SF4 ZINC FINGER PROTEIN 207 BUB3-INTERACTING AND GLEBS MOTIF-CONTAINING PROTEIN ZNF207 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;negative regulation of cell cycle#GO:0045786;microtubule-based process#GO:0007017;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;regulation of chromosome segregation#GO:0051983;cellular component assembly#GO:0022607;cell cycle checkpoint signaling#GO:0000075;cytoskeleton organization#GO:0007010;regulation of cell cycle process#GO:0010564;chromosome localization#GO:0050000;spindle assembly#GO:0051225;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic spindle assembly checkpoint signaling#GO:0007094;localization#GO:0051179;cell communication#GO:0007154;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;intracellular signal transduction#GO:0035556;organelle assembly#GO:0070925;negative regulation of chromosome organization#GO:2001251;organelle localization#GO:0051640;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;mitotic cell cycle checkpoint signaling#GO:0007093;microtubule cytoskeleton organization involved in mitosis#GO:1902850;negative regulation of cellular component organization#GO:0051129;spindle organization#GO:0007051;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;negative regulation of cell cycle process#GO:0010948;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;mitotic sister chromatid segregation#GO:0000070;regulation of mitotic cell cycle#GO:0007346;mitotic spindle assembly#GO:0090307;nuclear division#GO:0000280;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;mitotic spindle organization#GO:0007052;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;mitotic nuclear division#GO:0140014;cellular component organization or biogenesis#GO:0071840;negative regulation of chromosome segregation#GO:0051985;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of sister chromatid segregation#GO:0033046;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of cellular process#GO:0050794;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;negative regulation of organelle organization#GO:0010639;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;negative regulation of cellular process#GO:0048523;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007 chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000005249.4|UniProtKB=F7GH42 F7GH42 NUBP1 PTHR23264:SF35 NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP1 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000012804.4|UniProtKB=F7DZ45 F7DZ45 FOXB2 PTHR11829:SF215 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN B2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000002344.2|UniProtKB=F7GLS4 F7GLS4 RPP14 PTHR15441:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P14 RIBONUCLEASE P PROTEIN SUBUNIT P14 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654 organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;multimeric ribonuclease P complex#GO:0030681;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;endonuclease complex#GO:1905348;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000025054.2|UniProtKB=F6PLZ3 F6PLZ3 LOC107649227 PTHR33904:SF1 ESSENTIAL MCU REGULATOR, MITOCHONDRIAL ESSENTIAL MCU REGULATOR, MITOCHONDRIAL chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;mitochondrial calcium ion transmembrane transport#GO:0006851;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;mitochondrial calcium ion homeostasis#GO:0051560;metal ion transport#GO:0030001;homeostatic process#GO:0042592 transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;calcium channel complex#GO:0034704;mitochondrion#GO:0005739;transporter complex#GO:1990351;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966 MONDO|Ensembl=ENSMODG00000014576.3|UniProtKB=F7ASQ3 F7ASQ3 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000027513.2|UniProtKB=K7E5Q1 K7E5Q1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000017151.4|UniProtKB=A0A5F8GCD3 A0A5F8GCD3 PHTF2 PTHR12680:SF2 PUTATIVE HOMEODOMAIN TRANSCRIPTION FACTOR PHTF PROTEIN PHTF2 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000000486.3|UniProtKB=F6UA43 F6UA43 ARHGAP42 PTHR12552:SF3 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN 42 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 MONDO|Ensembl=ENSMODG00000043639.1|UniProtKB=A0A5F8H7V5 A0A5F8H7V5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000023249.1|UniProtKB=F6XQX5 F6XQX5 GPR88 PTHR24240:SF234 OPSIN G PROTEIN-COUPLED RECEPTOR 88 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;signal transduction#GO:0007165;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;cellular process#GO:0009987;detection of stimulus#GO:0051606;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to radiation#GO:0071478;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000005115.4|UniProtKB=A0A5F8GNL0 A0A5F8GNL0 TP53BP2 PTHR24131:SF8 APOPTOSIS-STIMULATING OF P53 PROTEIN APOPTOSIS-STIMULATING OF P53 PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;signaling#GO:0023052;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;intrinsic apoptotic signaling pathway#GO:0097193;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction by p53 class mediator#GO:0072331;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;apoptotic signaling pathway#GO:0097190 nucleus#GO:0005634;cell-cell junction#GO:0005911;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000006613.3|UniProtKB=F7GEU5 F7GEU5 TPD52 PTHR19307:SF12 TUMOR PROTEIN D52 TUMOR PROTEIN D52 multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;biological regulation#GO:0065007;hemopoiesis#GO:0030097;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;B cell activation#GO:0042113;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;cell development#GO:0048468;leukocyte differentiation#GO:0002521;leukocyte activation#GO:0045321;positive regulation of cell population proliferation#GO:0008284;mononuclear cell differentiation#GO:1903131;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127;immune system process#GO:0002376;cell activation#GO:0001775;lymphocyte differentiation#GO:0030098 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000007089.4|UniProtKB=F6UEG6 F6UEG6 SUGP1 PTHR23340:SF3 ARGININE/SERINE RICH SPLICING FACTOR SF4/14 SURP AND G-PATCH DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000011303.4|UniProtKB=A0A5F8GBR6 A0A5F8GBR6 CLCN5 PTHR45711:SF7 CHLORIDE CHANNEL PROTEIN H(+)_CL(-) EXCHANGE TRANSPORTER 5 channel activity#GO:0015267;voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;system process#GO:0003008;chloride transport#GO:0006821;transport#GO:0006810;multicellular organismal process#GO:0032501;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;renal system process#GO:0003014 lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;Golgi apparatus#GO:0005794;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000018695.4|UniProtKB=F7FQP6 F7FQP6 ERCC3 PTHR11274:SF18 RAD25/XP-B DNA REPAIR HELICASE GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE_TRANSLOCASE SUBUNIT XPB ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853 neurogenesis#GO:0022008;macromolecule metabolic process#GO:0043170;cellular developmental process#GO:0048869;developmental process#GO:0032502;transcription by RNA polymerase II#GO:0006366;epidermis development#GO:0008544;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;epithelium development#GO:0060429;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;macromolecule biosynthetic process#GO:0009059;system development#GO:0048731;anatomical structure development#GO:0048856;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nervous system development#GO:0007399;gene expression#GO:0010467;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;hair cell differentiation#GO:0035315;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;DNA-templated transcription initiation#GO:0006352 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;nucleotide-excision repair complex#GO:0000109;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIIH holo complex#GO:0005675;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 DNA helicase#PC00011;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000012511.4|UniProtKB=F6Q0S1 F6Q0S1 NTNG2 PTHR10574:SF27 NETRIN/LAMININ-RELATED NETRIN-G2 neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;tissue development#GO:0009888;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468 extracellular matrix protein#PC00102 Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344;Axon guidance mediated by netrin#P00009>Netrin#P00357 MONDO|Ensembl=ENSMODG00000019738.4|UniProtKB=F6X3T9 F6X3T9 WDR41 PTHR22805:SF2 WDR41-RELATED WD REPEAT-CONTAINING PROTEIN 41 MONDO|Ensembl=ENSMODG00000024649.2|UniProtKB=F6XBE0 F6XBE0 GCNT3 PTHR19297:SF81 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000024286.2|UniProtKB=F7GIE1 F7GIE1 LOC100025038 PTHR48018:SF90 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AK3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000043204.1|UniProtKB=A0A5F8G4T7 A0A5F8G4T7 TMEM69 PTHR15887:SF1 TRANSMEMBRANE PROTEIN 69 TRANSMEMBRANE PROTEIN 69 MONDO|Ensembl=ENSMODG00000024529.3|UniProtKB=F6ZVZ5 F6ZVZ5 LOC100022215 PTHR10137:SF5 V-TYPE PROTON ATPASE SUBUNIT C V-TYPE PROTON ATPASE SUBUNIT C 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324 cellular anatomical structure#GO:0110165;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;proton-transporting two-sector ATPase complex#GO:0016469 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000002562.4|UniProtKB=F7A1E8 F7A1E8 PLK3 PTHR24345:SF42 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK3 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;intracellular signal transduction#GO:0035556;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;Golgi organization#GO:0007030;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;microtubule-based process#GO:0007017;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;endomembrane system organization#GO:0010256;cytoskeleton organization#GO:0007010;regulation of cell cycle process#GO:0010564;organelle organization#GO:0006996;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;organelle disassembly#GO:1903008;regulation of mitotic cell cycle phase transition#GO:1901990;cellular component disassembly#GO:0022411;negative regulation of mitotic cell cycle#GO:0045930;cellular response to stress#GO:0033554;regulation of G1/S transition of mitotic cell cycle#GO:2000045;response to stimulus#GO:0050896;mitotic spindle organization#GO:0007052;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;cell cycle process#GO:0022402 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694;spindle pole#GO:0000922;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000002891.2|UniProtKB=F7B5Z5 F7B5Z5 WSCD2 PTHR45964:SF9 WSCD FAMILY MEMBER CG9164 SIALATE:O-SULFOTRANSFERASE 2 MONDO|Ensembl=ENSMODG00000009795.4|UniProtKB=A0A5F8GUM3 A0A5F8GUM3 MEGF11 PTHR24035:SF127 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 11 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 membrane organization#GO:0061024;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277;phagocytosis#GO:0006909;transport#GO:0006810;membrane invagination#GO:0010324;substrate adhesion-dependent cell spreading#GO:0034446;endocytosis#GO:0006897;cellular component organization#GO:0016043;localization#GO:0051179;cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155 basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000016519.4|UniProtKB=F7EQ32 F7EQ32 PTHR11005:SF45 LYSOSOMAL ACID LIPASE-RELATED LIPASE MEMBER K hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 lipase#PC00143;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000047129.1|UniProtKB=A0A5F8GMC5 A0A5F8GMC5 PTHR23267:SF511 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-9 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000045287.1|UniProtKB=F6S7N2 F6S7N2 PTHR24028:SF318 CADHERIN-87A PROTOCADHERIN BETA-16 cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000016798.4|UniProtKB=A0A5F8G8I3 A0A5F8G8I3 NTSR1 PTHR24243:SF9 G-PROTEIN COUPLED RECEPTOR NEUROTENSIN RECEPTOR TYPE 1 molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000001558.4|UniProtKB=F7BX77 F7BX77 PPP1R15B PTHR16489:SF11 GH11727P PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15B molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 response to stimulus#GO:0050896;cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;response to endoplasmic reticulum stress#GO:0034976 endoplasmic reticulum#GO:0005783;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000018059.4|UniProtKB=A0A5F8G7Q0 A0A5F8G7Q0 LTBR PTHR47607:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUBFAMILY MEMBER 3 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 3 protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899 regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003072.2|UniProtKB=F6PLI3 F6PLI3 NOP9 PTHR13102:SF0 NUCLEOLAR PROTEIN 9 NUCLEOLAR PROTEIN 9 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;transport#GO:0006810;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;nuclear transport#GO:0051169;rRNA processing#GO:0006364;nuclear export#GO:0051168;localization#GO:0051179;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;organelle localization#GO:0051640;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;90S preribosome#GO:0030686;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000010571.4|UniProtKB=A0A5F8G553 A0A5F8G553 SEZ6L PTHR45656:SF8 PROTEIN CBR-CLEC-78 SEIZURE 6-LIKE PROTEIN animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;brain development#GO:0007420;developmental maturation#GO:0021700;nervous system development#GO:0007399;head development#GO:0060322;cellular process#GO:0009987;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;cell junction organization#GO:0034330;central nervous system development#GO:0007417;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;postsynaptic membrane#GO:0045211;intracellular membrane-bounded organelle#GO:0043231;neuronal cell body#GO:0043025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell body#GO:0044297;postsynapse#GO:0098794;cell junction#GO:0030054;endoplasmic reticulum#GO:0005783;synaptic membrane#GO:0097060;cytoplasm#GO:0005737;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000051101.1|UniProtKB=A0A5F8GZ47 A0A5F8GZ47 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023 cell communication#GO:0007154;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of immune response#GO:0050776;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000043372.1|UniProtKB=A0A5F8GRF8 A0A5F8GRF8 monDomV1R1243 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014108.3|UniProtKB=H9H6P0 H9H6P0 PTHR47966:SF83 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED NAPSIN-A catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 lysosome#GO:0005764;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323 protease#PC00190;aspartic protease#PC00053 MONDO|Ensembl=ENSMODG00000021123.4|UniProtKB=A0A5F8HL35 A0A5F8HL35 PTHR11915:SF454 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular process#GO:0009987;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036 intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell periphery#GO:0071944;membrane#GO:0016020 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000016989.4|UniProtKB=F6U5G9 F6U5G9 RIT1 PTHR24070:SF208 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN RIT1 ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;calmodulin binding#GO:0005516;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000010936.4|UniProtKB=H9H6G5 H9H6G5 EXOC3L2 PTHR21292:SF7 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3-LIKE PROTEIN 2 binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515 vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;exocytosis#GO:0006887;secretion by cell#GO:0032940;transport#GO:0006810 cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;exocyst#GO:0000145;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000001498.3|UniProtKB=F7F4L1 F7F4L1 RCVRN PTHR23055:SF20 CALCIUM BINDING PROTEINS RECOVERIN small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 calmodulin-related#PC00061 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Recoverin#P00756 MONDO|Ensembl=ENSMODG00000001868.4|UniProtKB=F6SNF7 F6SNF7 TMEM65 PTHR21706:SF16 TRANSMEMBRANE PROTEIN 65 TRANSMEMBRANE PROTEIN 65 regulation of biological process#GO:0050789;heart development#GO:0007507;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of heart contraction#GO:0008016;regulation of system process#GO:0044057;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;system development#GO:0048731 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000010023.4|UniProtKB=A0A5F8G2I5 A0A5F8G2I5 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000045324.1|UniProtKB=A0A5F8HB18 A0A5F8HB18 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000043442.1|UniProtKB=A0A5F8H304 A0A5F8H304 LOC100617006 PTHR48018:SF109 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8U3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006139.4|UniProtKB=F7BSZ4 F7BSZ4 PTHR23052:SF1 AXONEMAL DYNEIN LIGHT CHAIN DOMAIN-CONTAINING PROTEIN 1 AXONEMAL DYNEIN LIGHT CHAIN DOMAIN-CONTAINING PROTEIN 1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000011865.4|UniProtKB=A0A5F8HJY2 A0A5F8HJY2 PTHR19282:SF169 TETRASPANIN TETRASPANIN-6 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000002724.4|UniProtKB=F6Z7I4 F6Z7I4 SHLD2 PTHR14495:SF2 SHIELDIN COMPLEX SUBUNIT 2 SHIELDIN COMPLEX SUBUNIT 2 regulation of response to stress#GO:0080134;regulation of DNA recombination#GO:0000018;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of double-strand break repair#GO:2000779;regulation of cellular response to stress#GO:0080135;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromosome#GO:0005694;site of double-strand break#GO:0035861 MONDO|Ensembl=ENSMODG00000007320.5|UniProtKB=F7CD60 F7CD60 VIRMA PTHR23185:SF0 PROTEIN VIRILIZER HOMOLOG PROTEIN VIRILIZER HOMOLOG protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000007425.3|UniProtKB=A0A5F8GCP5 A0A5F8GCP5 TMTC4 PTHR44227:SF3 FAMILY NOT NAMED PROTEIN O-MANNOSYL-TRANSFERASE TMTC4 mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;protein O-linked glycosylation via mannose#GO:0035269;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to unfolded protein#GO:0006986;cell communication#GO:0007154;protein metabolic process#GO:0019538;intracellular signal transduction#GO:0035556;glycoprotein biosynthetic process#GO:0009101;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;signal transduction#GO:0007165;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;biosynthetic process#GO:0009058;biological regulation#GO:0065007;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000015690.3|UniProtKB=F7E0T2 F7E0T2 PTX3 PTHR46943:SF1 PENTRAXIN-RELATED PROTEIN PTX3 PENTRAXIN-RELATED PROTEIN PTX3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;complement binding#GO:0001848 immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000013904.4|UniProtKB=F6VBS4 F6VBS4 SNRPC PTHR31148:SF1 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;cellular component assembly#GO:0022607;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;Sm-like protein family complex#GO:0120114;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;U1 snRNP#GO:0005685;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000019560.4|UniProtKB=A0A5F8GZD4 A0A5F8GZD4 PLK2 PTHR24345:SF44 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 G1/S transition of mitotic cell cycle#GO:0000082;regulation of synaptic plasticity#GO:0048167;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;organelle organization#GO:0006996;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;regulation of trans-synaptic signaling#GO:0099177;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;mitotic cell cycle phase transition#GO:0044772;regulation of signaling#GO:0023051;microtubule cytoskeleton organization#GO:0000226;regulation of biological quality#GO:0065008;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cell cycle phase transition#GO:0044770;mitotic spindle organization#GO:0007052;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;spindle pole#GO:0000922;chromosome#GO:0005694;kinetochore#GO:0000776;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000004473.4|UniProtKB=F6V9D4 F6V9D4 CASP3 PTHR10454:SF198 CASPASE CASPASE-3 enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;molecular function activator activity#GO:0140677;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;enzyme activator activity#GO:0008047;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;molecular function regulator activity#GO:0098772 positive regulation of neuron apoptotic process#GO:0043525;epidermis development#GO:0008544;developmental process#GO:0032502;macromolecule metabolic process#GO:0043170;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;multicellular organismal-level homeostasis#GO:0048871;positive regulation of cellular process#GO:0048522;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;multicellular organismal process#GO:0032501;tissue development#GO:0009888;biological regulation#GO:0065007;hemopoiesis#GO:0030097;keratinocyte differentiation#GO:0030216;homeostasis of number of cells#GO:0048872;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;system development#GO:0048731;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;cell death#GO:0008219;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;metabolic process#GO:0008152;neuron differentiation#GO:0030182;regulation of apoptotic process#GO:0042981;multicellular organism development#GO:0007275;positive regulation of apoptotic process#GO:0043065;animal organ development#GO:0048513;regulation of neuron apoptotic process#GO:0043523;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;skin development#GO:0043588;nervous system development#GO:0007399;proteolysis#GO:0006508;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cell differentiation#GO:0030154;positive regulation of programmed cell death#GO:0043068;myeloid cell differentiation#GO:0030099;cell development#GO:0048468 membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protease#PC00190 CCKR signaling map#P06959>Pro-caspase-3#P07231;Apoptosis signaling pathway#P00006>Caspase 3#P00305;FAS signaling pathway#P00020>Caspase3#P00599;CCKR signaling map#P06959>Caspase-3#P07108;FAS signaling pathway#P00020>Pro-Caspase3#P00608;Huntington disease#P00029>Caspase 3#P00812 MONDO|Ensembl=ENSMODG00000011522.3|UniProtKB=F6RI07 F6RI07 PCYOX1 PTHR15944:SF3 FARNESYLCYSTEINE LYASE PRENYLCYSTEINE OXIDASE 1 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 lyase#PC00144;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000015259.4|UniProtKB=F6U3T4 F6U3T4 PHF6 PTHR12420:SF15 PHD FINGER PROTEIN PHD FINGER PROTEIN 6 histone deacetylase binding#GO:0042826;protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899;histone binding#GO:0042393 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000000582.4|UniProtKB=F6WP14 F6WP14 ADGRA3 PTHR45930:SF2 G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR A3 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000038617.1|UniProtKB=A0A5F8GII7 A0A5F8GII7 PTHR31129:SF3 GLYCOPROTEIN HORMONE ALPHA-2 GLYCOPROTEIN HORMONE ALPHA-2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;G protein-coupled receptor binding#GO:0001664 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 MONDO|Ensembl=ENSMODG00000043775.1|UniProtKB=A0A5F8HGH3 A0A5F8HGH3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000025432.1|UniProtKB=F6VLZ9 F6VLZ9 LOC100014813 PTHR47507:SF7 BARRIER TO AUTOINTEGRATION FACTOR 2 BARRIER-TO-AUTOINTEGRATION FACTOR nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000004649.4|UniProtKB=F6UN04 F6UN04 ADAM33 PTHR11905:SF38 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 33 metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000002038.4|UniProtKB=F6QW39 F6QW39 RASSF5 PTHR22738:SF9 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 5 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000009754.4|UniProtKB=F6WT78 F6WT78 SNX8 PTHR46571:SF1 SORTING NEXIN-8 SORTING NEXIN-8 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cytosolic transport#GO:0016482;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;early endosome membrane#GO:0031901 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000025397.2|UniProtKB=F7GG16 F7GG16 PTHR10809:SF155 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN A protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron differentiation#GO:0030182;endoplasmic reticulum membrane organization#GO:0090158;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;anatomical structure development#GO:0048856 membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000008355.3|UniProtKB=F7EK48 F7EK48 TMEM151A PTHR31893:SF3 TRANSMEMBRANE PROTEIN 151 HOMOLOG TRANSMEMBRANE PROTEIN 151A cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000018193.4|UniProtKB=F7B751 F7B751 GUCY2C PTHR11920:SF347 GUANYLYL CYCLASE GUANYLYL CYCLASE C signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383;peptide receptor activity#GO:0001653;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;lyase activity#GO:0016829;molecular transducer activity#GO:0060089 cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;ribose phosphate biosynthetic process#GO:0046390;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;organophosphate biosynthetic process#GO:0090407;enzyme-linked receptor protein signaling pathway#GO:0007167;cGMP biosynthetic process#GO:0006182;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 lyase#PC00144;guanylate cyclase#PC00114 MONDO|Ensembl=ENSMODG00000025714.3|UniProtKB=A0A5F8GKT3 A0A5F8GKT3 LOC100021431 PTHR11005:SF45 LYSOSOMAL ACID LIPASE-RELATED LIPASE MEMBER K lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 hydrolase#PC00121;lipase#PC00143 MONDO|Ensembl=ENSMODG00000018320.3|UniProtKB=F6PTI9 F6PTI9 HSPBAP1 PTHR12461:SF43 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED HSPB1-ASSOCIATED PROTEIN 1 dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000014234.2|UniProtKB=F6T947 F6T947 SLC38A7 PTHR22950:SF192 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 7 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 amino acid transporter#PC00046;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000037411.1|UniProtKB=A0A5F8GND4 A0A5F8GND4 FAM89A PTHR46949:SF3 LEUCINE REPEAT ADAPTER PROTEIN 25 PROTEIN FAM89A scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005695.3|UniProtKB=F6UKT9 F6UKT9 NAIF1 PTHR23098:SF7 AGAP001331-PA-RELATED NUCLEAR APOPTOSIS-INDUCING FACTOR 1 MONDO|Ensembl=ENSMODG00000014654.3|UniProtKB=A0A5F8GLJ9 A0A5F8GLJ9 SUMF2 PTHR23150:SF33 SULFATASE MODIFYING FACTOR 1, 2 INACTIVE C-ALPHA-FORMYLGLYCINE-GENERATING ENZYME 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000018269.4|UniProtKB=F6Q744 F6Q744 SLC15A2 PTHR11654:SF603 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 2 oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 import across plasma membrane#GO:0098739;peptide transport#GO:0015833;nitrogen compound transport#GO:0071705;oligopeptide transmembrane transport#GO:0035672;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;import into cell#GO:0098657;dipeptide transport#GO:0042938;oligopeptide transport#GO:0006857;transport#GO:0006810 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transporter#PC00227 MONDO|Ensembl=ENSMODG00000004648.4|UniProtKB=A0A5F8GLD1 A0A5F8GLD1 TLL2 PTHR10127:SF866 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING TOLLOID-LIKE PROTEIN 2 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501;regionalization#GO:0003002;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;metabolic process#GO:0008152;dorsal/ventral pattern formation#GO:0009953;primary metabolic process#GO:0044238;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;pattern specification process#GO:0007389;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000000314.4|UniProtKB=A0A5F8H1J6 A0A5F8H1J6 RPN2 PTHR12640:SF0 RIBOPHORIN II DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 2 biosynthetic process#GO:0009058;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000042482.1|UniProtKB=A0A5F8GYP4 A0A5F8GYP4 LOC103103094 PTHR24404:SF96 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000013612.5|UniProtKB=F6VF30 F6VF30 LRWD1 PTHR24370:SF10 OPTICIN LEUCINE-RICH REPEAT AND WD REPEAT-CONTAINING PROTEIN 1 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000008681.4|UniProtKB=H9H6A5 H9H6A5 LOC100030473 PTHR24257:SF15 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER MYELOBLASTIN catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000007782.5|UniProtKB=F7AW98 F7AW98 SLC35F4 PTHR19346:SF2 SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN SOLUTE CARRIER FAMILY 35 MEMBER F4 MONDO|Ensembl=ENSMODG00000015912.4|UniProtKB=F6ZRU3 F6ZRU3 E4F1 PTHR24408:SF31 ZINC FINGER PROTEIN TRANSCRIPTION FACTOR E4F1 sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000044194.1|UniProtKB=A0A5F8H6G1 A0A5F8H6G1 PTHR10728:SF39 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 GAMMA lipase activity#GO:0016298;small molecule binding#GO:0036094;ion binding#GO:0043167;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;lipid binding#GO:0008289;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623 glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475;metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;Angiogenesis#P00005>cPLA2#P00251 MONDO|Ensembl=ENSMODG00000039738.1|UniProtKB=A0A5F8GA52 A0A5F8GA52 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000028637.2|UniProtKB=K7E434 K7E434 TROAP PTHR15289:SF3 TASTIN TASTIN MONDO|Ensembl=ENSMODG00000013725.4|UniProtKB=A0A5F8G1V0 A0A5F8G1V0 GRAMD1A PTHR23319:SF8 GRAM DOMAIN CONTAINING 1B, ISOFORM E PROTEIN ASTER-A steroid binding#GO:0005496;cholesterol transfer activity#GO:0120020;alcohol binding#GO:0043178;transporter activity#GO:0005215;sterol transfer activity#GO:0120015;cholesterol binding#GO:0015485;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;lipid carrier activity#GO:0005319;sterol binding#GO:0032934;molecular carrier activity#GO:0140104;binding#GO:0005488;small molecule binding#GO:0036094 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;intracellular sterol transport#GO:0032366;lipid transport#GO:0006869;transport#GO:0006810;intracellular transport#GO:0046907;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;cellular localization#GO:0051641;sterol transport#GO:0015918;localization#GO:0051179 organelle membrane contact site#GO:0044232;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000003147.3|UniProtKB=F6WU00 F6WU00 NOTUM PTHR21562:SF7 NOTUM-RELATED PALMITOLEOYL-PROTEIN CARBOXYLESTERASE NOTUM MONDO|Ensembl=ENSMODG00000013770.3|UniProtKB=A0A5F8H2L9 A0A5F8H2L9 PAX8 PTHR45636:SF6 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-8 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000015745.3|UniProtKB=A0A5F8GUE4 A0A5F8GUE4 PLD1 PTHR18896:SF57 PHOSPHOLIPASE D PHOSPHOLIPASE D1 lipase activity#GO:0016298;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 organophosphate catabolic process#GO:0046434;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;regulation of localization#GO:0032879;regulation of transport#GO:0051049;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708 lipase#PC00143;phospholipase#PC00186 Angiogenesis#P00005>PLD#P00204;Ras Pathway#P04393>PLD#P04574 MONDO|Ensembl=ENSMODG00000045878.1|UniProtKB=A0A5F8H772 A0A5F8H772 LOC107648884 PTHR24390:SF250 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 763 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000042282.1|UniProtKB=A0A5F8G3C7 A0A5F8G3C7 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001240.4|UniProtKB=F7FX19 F7FX19 LHCGR PTHR24372:SF1 GLYCOPROTEIN HORMONE RECEPTOR LUTROPIN-CHORIOGONADOTROPIC HORMONE RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;gonad development#GO:0008406;development of primary male sexual characteristics#GO:0046546;developmental process#GO:0032502;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;male sex differentiation#GO:0046661;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;anatomical structure development#GO:0048856;female gonad development#GO:0008585;system development#GO:0048731;reproductive system development#GO:0061458;multicellular organismal reproductive process#GO:0048609;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to chemical#GO:0042221;response to hormone#GO:0009725;signal transduction#GO:0007165;male gonad development#GO:0008584;sex differentiation#GO:0007548;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;development of primary sexual characteristics#GO:0045137;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;reproductive structure development#GO:0048608;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;hormone-mediated signaling pathway#GO:0009755;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;rhythmic process#GO:0048511 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000029372.2|UniProtKB=K7DZM6 K7DZM6 STYX PTHR46588:SF1 SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN SERINE_THREONINE_TYROSINE-INTERACTING PROTEIN regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;regulation of catabolic process#GO:0009894;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of protein metabolic process#GO:0051248;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000042807.1|UniProtKB=A0A5F8GTR6 A0A5F8GTR6 PTHR18860:SF131 14-3-3 PROTEIN 14-3-3 DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000045969.1|UniProtKB=A0A5F8GXI5 A0A5F8GXI5 WDR83OS PTHR13193:SF0 CGI-140 PAT COMPLEX SUBUNIT ASTERIX cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000013427.3|UniProtKB=F7C526 F7C526 SNX24 PTHR15813:SF10 SORTING NEXIN-22 AND 24 SORTING NEXIN-24 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000009987.3|UniProtKB=F6USU5 F6USU5 TMEM72 PTHR28474:SF1 TRANSMEMBRANE PROTEIN 72 TRANSMEMBRANE PROTEIN 72 MONDO|Ensembl=ENSMODG00000046925.1|UniProtKB=K7E396 K7E396 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024484.3|UniProtKB=A0A5F8GSI0 A0A5F8GSI0 DNAH12 PTHR10676:SF255 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 12 macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;microtubule motor activity#GO:0003777;protein binding#GO:0005515 male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;cellular developmental process#GO:0048869;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cell projection organization#GO:0030030;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003;sperm motility#GO:0097722;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;inner dynein arm assembly#GO:0036159;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;inner dynein arm#GO:0036156;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;dynein complex#GO:0030286;axonemal dynein complex#GO:0005858;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;catalytic complex#GO:1902494;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000010301.3|UniProtKB=F6SSD2 F6SSD2 PTHR24068:SF63 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 E3 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein K11-linked ubiquitination#GO:0070979;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein K63-linked ubiquitination#GO:0070534;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein K48-linked ubiquitination#GO:0070936;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000012253.4|UniProtKB=A0A5F8GDT4 A0A5F8GDT4 CLIP1 PTHR18916:SF44 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 1 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of protein polymerization#GO:0032273;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component organization or biogenesis#GO:0071840;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;cytoplasmic microtubule organization#GO:0031122;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of microtubule-based process#GO:0032886;positive regulation of cellular component organization#GO:0051130;microtubule cytoskeleton organization#GO:0000226;positive regulation of organelle organization#GO:0010638;supramolecular fiber organization#GO:0097435;regulation of microtubule polymerization#GO:0031113 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule end#GO:1990752;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;nucleus#GO:0005634;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;cytoskeleton#GO:0005856 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000004250.4|UniProtKB=F6UB15 F6UB15 LETM1 PTHR14009:SF8 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139 monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;cellular component organization#GO:0016043;metal ion transport#GO:0030001;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;organelle organization#GO:0006996;mitochondrial calcium ion transmembrane transport#GO:0006851;cellular process#GO:0009987;mitochondrion organization#GO:0007005;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000013054.4|UniProtKB=F7G0U6 F7G0U6 RBX1 PTHR11210:SF2 RING BOX E3 UBIQUITIN-PROTEIN LIGASE RBX1 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000007605.4|UniProtKB=F7F799 F7F799 ITGB4 PTHR10082:SF42 INTEGRIN BETA SUBUNIT INTEGRIN BETA-4 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515 cell adhesion mediated by integrin#GO:0033627;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell migration#GO:0016477;signal transduction#GO:0007165;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;signaling#GO:0023052;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;integrin-mediated signaling pathway#GO:0007229 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;cell junction#GO:0030054;anchoring junction#GO:0070161;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;focal adhesion#GO:0005925;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 MONDO|Ensembl=ENSMODG00000009169.3|UniProtKB=F7ADI7 F7ADI7 LOC100010460 PTHR24103:SF676 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000009625.4|UniProtKB=F6RDV4 F6RDV4 RCN1 PTHR10827:SF17 RETICULOCALBIN RETICULOCALBIN-1 ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000041358.1|UniProtKB=K7DZR0 K7DZR0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000014337.3|UniProtKB=F6ULQ3 F6ULQ3 PTHR12357:SF3 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING PROTEIN 1 protein-RNA adaptor activity#GO:0140517;molecular adaptor activity#GO:0060090;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of mRNA metabolic process#GO:1903311;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;mRNA processing#GO:0006397;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000010464.4|UniProtKB=F7F7K0 F7F7K0 PAOX PTHR10742:SF429 FLAVIN MONOAMINE OXIDASE PEROXISOMAL N(1)-ACETYL-SPERMINE_SPERMIDINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolic process#GO:0008152;polyamine catabolic process#GO:0006598;amine catabolic process#GO:0009310;catabolic process#GO:0009056;biogenic amine metabolic process#GO:0006576;amine metabolic process#GO:0009308;polyamine metabolic process#GO:0006595;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidase#PC00175 MONDO|Ensembl=ENSMODG00000008405.4|UniProtKB=F7BUN6 F7BUN6 NSMCE4A PTHR16140:SF0 NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4 NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152 nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000009914.4|UniProtKB=F6R9C5 F6R9C5 NBEA PTHR13743:SF62 BEIGE/BEACH-RELATED NEUROBEACHIN enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007136.4|UniProtKB=F6RZC7 F6RZC7 RPL7 PTHR11524:SF12 60S RIBOSOMAL PROTEIN L7 LARGE RIBOSOMAL SUBUNIT PROTEIN UL30 binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000019182.4|UniProtKB=F7AWM0 F7AWM0 CXCL8 PTHR12015:SF198 SMALL INDUCIBLE CYTOKINE A INTERLEUKIN-8 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102 cell migration#GO:0016477;response to other organism#GO:0051707;immune response#GO:0006955;cellular response to molecule of bacterial origin#GO:0071219;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;leukocyte migration#GO:0050900;cell motility#GO:0048870;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326;response to bacterium#GO:0009617;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;response to lipid#GO:0033993;taxis#GO:0042330;neutrophil migration#GO:1990266;response to chemical#GO:0042221;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;cellular response to oxygen-containing compound#GO:1901701;response to lipopolysaccharide#GO:0032496;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;neutrophil chemotaxis#GO:0030593;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;biological process involved in interspecies interaction between organisms#GO:0044419;response to molecule of bacterial origin#GO:0002237;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 CCKR signaling map#P06959>IL8#G07296;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856;CCKR signaling map#P06959>IL8#G07001;CCKR signaling map#P06959>IL8#P07136;Interleukin signaling pathway#P00036>Interleukin#P00970 MONDO|Ensembl=ENSMODG00000020081.3|UniProtKB=F7GI56 F7GI56 LRRC55 PTHR46473:SF5 GH08155P LEUCINE-RICH REPEAT-CONTAINING PROTEIN 55 monoatomic cation transmembrane transporter activity#GO:0008324;molecular function activator activity#GO:0140677;voltage-gated channel activity#GO:0022832;protein binding#GO:0005515;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;potassium channel regulator activity#GO:0015459;voltage-gated monoatomic ion channel activity#GO:0005244;binding#GO:0005488;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;channel activity#GO:0015267;channel regulator activity#GO:0016247;potassium ion transmembrane transporter activity#GO:0015079;transporter regulator activity#GO:0141108;potassium channel activity#GO:0005267;transmembrane transporter binding#GO:0044325;molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796 MONDO|Ensembl=ENSMODG00000012013.4|UniProtKB=F7AMB3 F7AMB3 PTHR16046:SF10 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR 2 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 2 intracellular protein localization#GO:0008104;regulation of response to stress#GO:0080134;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of response to stimulus#GO:0048584;positive regulation of DNA repair#GO:0045739;biological regulation#GO:0065007;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of metabolic process#GO:0009893;localization#GO:0051179;regulation of double-strand break repair#GO:2000779;regulation of cellular response to stress#GO:0080135;cellular response to stress#GO:0033554;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;positive regulation of double-strand break repair#GO:2000781;positive regulation of DNA metabolic process#GO:0051054;cellular response to stimulus#GO:0051716;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789 nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000027706.2|UniProtKB=K7E462 K7E462 C8H13orf46 PTHR39223:SF1 RIKEN CDNA 1700029H14 GENE 1700029H14RIK PROTEIN MONDO|Ensembl=ENSMODG00000023230.1|UniProtKB=F6VEC3 F6VEC3 LOC100030615 PTHR19424:SF3 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR-BINDING PROTEIN 1 response to temperature stimulus#GO:0009266;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950;cellular response to heat#GO:0034605;response to heat#GO:0009408;heat acclimation#GO:0010286;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000045674.1|UniProtKB=K7E4S8 K7E4S8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000037619.1|UniProtKB=A0A5F8G418 A0A5F8G418 LOC100619187 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005273.4|UniProtKB=F7E6Z2 F7E6Z2 ENO3 PTHR11902:SF5 ENOLASE BETA-ENOLASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;phosphopyruvate hydratase activity#GO:0004634;catalytic activity#GO:0003824 purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;lyase#PC00144 MONDO|Ensembl=ENSMODG00000000682.4|UniProtKB=F7EP78 F7EP78 HERC2 PTHR22870:SF398 REGULATOR OF CHROMOSOME CONDENSATION E3 UBIQUITIN-PROTEIN LIGASE HERC2 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000007477.6|UniProtKB=F7CRH0 F7CRH0 LLGL2 PTHR10241:SF20 LETHAL 2 GIANT LARVAE PROTEIN LLGL SCRIBBLE CELL POLARITY COMPLEX COMPONENT 2 cytoskeletal protein binding#GO:0008092;enzyme activator activity#GO:0008047;SNARE binding#GO:0000149;myosin binding#GO:0017022;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;binding#GO:0005488;syntaxin binding#GO:0019905;molecular function activator activity#GO:0140677;protein binding#GO:0005515;enzyme regulator activity#GO:0030234 post-Golgi vesicle-mediated transport#GO:0006892;secretion by cell#GO:0032940;cellular localization#GO:0051641;spindle localization#GO:0051653;regulation of signaling#GO:0023051;establishment or maintenance of cell polarity#GO:0007163;export from cell#GO:0140352;establishment of organelle localization#GO:0051656;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;exocytosis#GO:0006887;cellular component organization or biogenesis#GO:0071840;Golgi vesicle transport#GO:0048193;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;regulation of establishment or maintenance of cell polarity#GO:0032878;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;secretion#GO:0046903;cortical actin cytoskeleton organization#GO:0030866;localization#GO:0051179;regulation of Notch signaling pathway#GO:0008593;actin filament-based process#GO:0030029;localization within membrane#GO:0051668;organelle localization#GO:0051640;cortical cytoskeleton organization#GO:0030865;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;Golgi to plasma membrane transport#GO:0006893;establishment of cell polarity#GO:0030010;cell cycle#GO:0007049;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;regulation of response to stimulus#GO:0048583;transport#GO:0006810;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;establishment of spindle localization#GO:0051293 intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;membrane#GO:0016020;cortical cytoskeleton#GO:0030863;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000024156.2|UniProtKB=F6XXY1 F6XXY1 MRPL57 PTHR14520:SF4 MITOCHONDRIAL RIBOSOMAL PROTEIN 63 LARGE RIBOSOMAL SUBUNIT PROTEIN ML63 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000005498.4|UniProtKB=A0A5F8GPE9 A0A5F8GPE9 RIMS2 PTHR12157:SF15 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2 structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;regulation of exocytosis#GO:0017157;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;regulation of localization#GO:0032879;regulation of transport#GO:0051049;protein-containing complex organization#GO:0043933;regulated exocytosis#GO:0045055;exocytic process#GO:0140029;cellular component assembly#GO:0022607;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;regulation of neurotransmitter secretion#GO:0046928;signaling#GO:0023052;export from cell#GO:0140352;regulation of synaptic vesicle exocytosis#GO:2000300;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;protein-containing complex assembly#GO:0065003 synaptic membrane#GO:0097060;cell junction#GO:0030054;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell cortex#GO:0005938;presynapse#GO:0098793;cell periphery#GO:0071944;plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;presynaptic membrane#GO:0042734 membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>RIM1alpha/2alpha#P05776 MONDO|Ensembl=ENSMODG00000020601.4|UniProtKB=F6ZBY0 F6ZBY0 RPL34 PTHR46595:SF2 60S RIBOSOMAL PROTEIN L34 LARGE RIBOSOMAL SUBUNIT PROTEIN EL34 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000008951.3|UniProtKB=F7GCQ7 F7GCQ7 PTHR26453:SF173 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T11 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008378.4|UniProtKB=F7CDT9 F7CDT9 STK24 PTHR48012:SF22 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE 24 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013;regulation of locomotion#GO:0040012;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of cell motility#GO:2000145;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000021343.4|UniProtKB=F7FSN0 F7FSN0 LOC100028638 PTHR12612:SF9 NUCLEAR TRANSPORT FACTOR 2 NTF2-RELATED EXPORT PROTEIN 2-RELATED gene expression#GO:0010467;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;transport#GO:0006810;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913 membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nucleus#GO:0005634;organelle envelope#GO:0031967 MONDO|Ensembl=ENSMODG00000012310.2|UniProtKB=F7EIT9 F7EIT9 HOXB13 PTHR45804:SF6 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-B13 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000013129.4|UniProtKB=F7B076 F7B076 KIF6 PTHR24115:SF194 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF6 protein binding#GO:0005515;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000001179.4|UniProtKB=F6YK45 F6YK45 TTC39A PTHR31859:SF3 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39A MONDO|Ensembl=ENSMODG00000002329.5|UniProtKB=F7GLZ3 F7GLZ3 ZNF777 PTHR24399:SF77 ZINC FINGER AND BTB DOMAIN-CONTAINING ZFP14 ZINC FINGER PROTEIN transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000012281.4|UniProtKB=F6YFX3 F6YFX3 COQ10B PTHR12901:SF9 SPERM PROTEIN HOMOLOG COENZYME Q-BINDING PROTEIN COQ10 HOMOLOG B, MITOCHONDRIAL intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000036502.1|UniProtKB=A0A5F8HDS4 A0A5F8HDS4 KPLCE PTHR23263:SF125 SMALL PROLINE-RICH PROTEIN SMALL PROLINE-RICH PROTEIN 3 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000012045.3|UniProtKB=F7ALH7 F7ALH7 TBX5 PTHR11267:SF28 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX5 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 heart development#GO:0007507;cellular process#GO:0009987;animal organ development#GO:0048513;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;cell fate specification#GO:0001708;circulatory system development#GO:0072359;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;heart morphogenesis#GO:0003007;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;pattern specification process#GO:0007389 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 MONDO|Ensembl=ENSMODG00000039038.1|UniProtKB=A0A5F8GWY1 A0A5F8GWY1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008593.3|UniProtKB=F7BTZ4 F7BTZ4 PTHR46538:SF2 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE MONDO|Ensembl=ENSMODG00000011354.4|UniProtKB=F6T5F1 F6T5F1 SUSD6 PTHR46839:SF2 SUSHI DOMAIN-CONTAINING PROTEIN 6 SUSHI DOMAIN-CONTAINING PROTEIN 6 MONDO|Ensembl=ENSMODG00000010848.3|UniProtKB=A0A5F8GGC3 A0A5F8GGC3 ADGRA2 PTHR45930:SF1 G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR A2 positive regulation of signal transduction#GO:0009967;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;tube development#GO:0035295;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of canonical Wnt signaling pathway#GO:0090263;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;circulatory system development#GO:0072359;response to stimulus#GO:0050896;central nervous system development#GO:0007417;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;sprouting angiogenesis#GO:0002040;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;angiogenesis#GO:0001525;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of Wnt signaling pathway#GO:0030177;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646 membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000020673.4|UniProtKB=F7DLA5 F7DLA5 KDR PTHR24416:SF45 TYROSINE-PROTEIN KINASE RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;regulation of anatomical structure morphogenesis#GO:0022603;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;angiogenesis#GO:0001525;positive regulation of cell motility#GO:2000147;positive regulation of cell population proliferation#GO:0008284;positive regulation of angiogenesis#GO:0045766;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;response to stimulus#GO:0050896;cell differentiation#GO:0030154;circulatory system development#GO:0072359;signaling#GO:0023052;regulation of vasculature development#GO:1901342;positive regulation of developmental process#GO:0051094;regulation of cell migration#GO:0030334;endothelial cell differentiation#GO:0045446;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;cell migration#GO:0016477;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;tube development#GO:0035295;regulation of locomotion#GO:0040012;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;regulation of angiogenesis#GO:0045765;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>VEGFR-2#P00222;VEGF signaling pathway#P00056>VEGFR-2#P01403 MONDO|Ensembl=ENSMODG00000004680.3|UniProtKB=F6U6I4 F6U6I4 PTGR1 PTHR43205:SF93 PROSTAGLANDIN REDUCTASE PROSTAGLANDIN REDUCTASE 1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;prostaglandin metabolic process#GO:0006693;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;icosanoid metabolic process#GO:0006690;small molecule metabolic process#GO:0044281 reductase#PC00198 MONDO|Ensembl=ENSMODG00000020691.4|UniProtKB=A0A5F8GJL6 A0A5F8GJL6 CRACD PTHR47574:SF3 CANCER-RELATED REGULATOR OF ACTIN DYNAMICS CAPPING PROTEIN-INHIBITING REGULATOR OF ACTIN DYNAMICS tissue homeostasis#GO:0001894;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;regulation of actin filament depolymerization#GO:0030834;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;system process#GO:0003008;regulation of protein depolymerization#GO:1901879;multicellular organismal-level homeostasis#GO:0048871;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;digestion#GO:0007586;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;positive regulation of organelle organization#GO:0010638;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;anatomical structure homeostasis#GO:0060249;positive regulation of cellular component biogenesis#GO:0044089;epithelial structure maintenance#GO:0010669;regulation of actin cytoskeleton organization#GO:0032956 MONDO|Ensembl=ENSMODG00000019787.4|UniProtKB=A0A5F8GIT8 A0A5F8GIT8 MVB12B PTHR31547:SF1 MULTIVESICULAR BODY SUBUNIT 12B MULTIVESICULAR BODY SUBUNIT 12B regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;ESCRT I complex#GO:0000813;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768 MONDO|Ensembl=ENSMODG00000018387.4|UniProtKB=F6RRE7 F6RRE7 LMLN PTHR10942:SF0 LEISHMANOLYSIN-LIKE PEPTIDASE LEISHMANOLYSIN-LIKE PEPTIDASE catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metalloprotease#PC00153;protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000005605.4|UniProtKB=F7A394 F7A394 TMEM185A PTHR13568:SF6 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 185B MONDO|Ensembl=ENSMODG00000010417.3|UniProtKB=F7A6U0 F7A6U0 STEAP2 PTHR14239:SF6 DUDULIN-RELATED METALLOREDUCTASE STEAP2 ferric-chelate reductase activity#GO:0000293;catalytic activity#GO:0003824;oxidoreductase activity, acting on metal ions#GO:0016722;oxidoreductase activity#GO:0016491 transport#GO:0006810;transition metal ion transport#GO:0000041;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020 reductase#PC00198 MONDO|Ensembl=ENSMODG00000003767.3|UniProtKB=F7AAI0 F7AAI0 TSHR PTHR24372:SF0 GLYCOPROTEIN HORMONE RECEPTOR THYROTROPIN RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000003733.3|UniProtKB=F7EVP5 F7EVP5 LTC4S PTHR10250:SF4 MICROSOMAL GLUTATHIONE S-TRANSFERASE LEUKOTRIENE C4 SYNTHASE oxidoreductase activity#GO:0016491;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;carbon-sulfur lyase activity#GO:0016846;lyase activity#GO:0016829;glutathione transferase activity#GO:0004364 small molecule metabolic process#GO:0044281;icosanoid metabolic process#GO:0006690;icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 transferase#PC00220 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Lipoxygenase#P00830 MONDO|Ensembl=ENSMODG00000049288.1|UniProtKB=A0A5F8GRK1 A0A5F8GRK1 PTHR10681:SF182 THIOREDOXIN PEROXIDASE THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE, MITOCHONDRIAL oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;response to oxidative stress#GO:0006979;cellular process#GO:0009987;response to stress#GO:0006950;hydrogen peroxide metabolic process#GO:0042743;homeostatic process#GO:0042592;response to stimulus#GO:0050896;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 peroxidase#PC00180;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000004467.4|UniProtKB=F6VRQ6 F6VRQ6 IARS2 PTHR42765:SF3 SOLEUCYL-TRNA SYNTHETASE ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000008078.4|UniProtKB=F6YJ94 F6YJ94 PRTG PTHR10075:SF147 BASIGIN RELATED PROTOGENIN cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000005418.4|UniProtKB=F7FVD7 F7FVD7 TMED8 PTHR22973:SF3 LD35087P PROTEIN TMED8 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000010727.3|UniProtKB=H9H6E8 H9H6E8 DDX21 PTHR47958:SF109 ATP-DEPENDENT RNA HELICASE DBP3 NUCLEOLAR RNA HELICASE 2 ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000004647.5|UniProtKB=A0A5F8GEJ1 A0A5F8GEJ1 CFAP97 PTHR23035:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97 MONDO|Ensembl=ENSMODG00000012970.4|UniProtKB=F7DBT1 F7DBT1 PTHR12876:SF26 N4BP1-RELATED NEDD4-BINDING PROTEIN 1 nuclease activity#GO:0004518;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 negative regulation of protein ubiquitination#GO:0031397;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA stability#GO:0043487;regulation of protein catabolic process#GO:0042176;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of mRNA catabolic process#GO:0061014;negative regulation of protein metabolic process#GO:0051248;positive regulation of RNA metabolic process#GO:0051254;negative regulation of proteasomal protein catabolic process#GO:1901799;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of protein ubiquitination#GO:0031396;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of protein modification process#GO:0031399;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;nucleoplasm#GO:0005654;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nuclear body#GO:0016604;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000036612.1|UniProtKB=F6QSG0 F6QSG0 LOC100012591 PTHR48001:SF128 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007613.3|UniProtKB=F7C5K6 F7C5K6 PTHR48001:SF24 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021418.4|UniProtKB=A0A5F8GQR0 A0A5F8GQR0 CEP192 PTHR16029:SF11 CENTROSOMAL PROTEIN OF 192 KDA CENTROSOMAL PROTEIN OF 192 KDA microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein localization to microtubule organizing center#GO:1905508;nuclear division#GO:0000280;mitotic spindle organization#GO:0007052;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;nuclear chromosome segregation#GO:0098813;chromosome organization#GO:0051276;intracellular protein localization#GO:0008104;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;protein localization to microtubule cytoskeleton#GO:0072698;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;macromolecule localization#GO:0033036;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;organelle assembly#GO:0070925;protein localization to organelle#GO:0033365;mitotic cell cycle#GO:0000278;protein localization to centrosome#GO:0071539;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cytoplasm#GO:0005737;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000015910.2|UniProtKB=F6ZRV6 F6ZRV6 PLA2G2E PTHR11716:SF56 PHOSPHOLIPASE A2 FAMILY MEMBER GROUP IIE SECRETORY PHOSPHOLIPASE A2 lipid binding#GO:0008289;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;A2-type glycerophospholipase activity#GO:0004623;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;cation binding#GO:0043169;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;small molecule binding#GO:0036094;ion binding#GO:0043167;hydrolase activity, acting on ester bonds#GO:0016788;phospholipid binding#GO:0005543;catalytic activity#GO:0003824 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;glycerolipid metabolic process#GO:0046486;phosphatidylglycerol metabolic process#GO:0046471;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000045357.1|UniProtKB=A0A5F8HEN4 A0A5F8HEN4 BTBD17 PTHR24410:SF12 HL07962P-RELATED BTB_POZ DOMAIN-CONTAINING PROTEIN 17 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000008478.5|UniProtKB=F7GEJ7 F7GEJ7 IRF2BP2 PTHR10816:SF18 MYELIN TRANSCRIPTION FACTOR 1-RELATED INTERFERON REGULATORY FACTOR 2-BINDING PROTEIN 2 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000006416.3|UniProtKB=F7FD30 F7FD30 PTHR26453:SF17 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011604.4|UniProtKB=F6UHK2 F6UHK2 ANXA2 PTHR10502:SF18 ANNEXIN ANNEXIN A2-RELATED lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;phospholipid binding#GO:0005543;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167 regulation of proteolysis#GO:0030162;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of protein metabolic process#GO:0051247;cell adhesion#GO:0007155;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle#GO:0031982;nucleus#GO:0005634;cell periphery#GO:0071944 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000006336.2|UniProtKB=F7AGA4 F7AGA4 LOC100030489 PTHR28264:SF1 CYTOCHROME C OXIDASE SUBUNIT 7A CYTOCHROME C OXIDASE SUBUNIT 6C primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055 oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987 oxidase#PC00175 MONDO|Ensembl=ENSMODG00000017976.4|UniProtKB=F7BV22 F7BV22 SLC2A3 PTHR23503:SF99 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643;carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180;import across plasma membrane#GO:0098739;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000014668.3|UniProtKB=F7E823 F7E823 PTHR24055:SF584 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell surface receptor signaling pathway#GO:0007166;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Parkinson disease#P00049>ERK#P01211;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Apoptosis signaling pathway#P00006>MAPK#P00269;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;Endothelin signaling pathway#P00019>ERK#P00566;Ras Pathway#P04393>ERK#P04542;T cell activation#P00053>ERK#P01300;PDGF signaling pathway#P00047>ERK#P01143;Angiogenesis#P00005>MEK#P00225;CCKR signaling map#P06959>MAPK1/3#P07228;Integrin signalling pathway#P00034>ERK#P00907;Interleukin signaling pathway#P00036>ERK#P00965;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>MAPK#P05937;B cell activation#P00010>ERK#P00371;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;CCKR signaling map#P06959>MAPK1#P07166;VEGF signaling pathway#P00056>MEK#P01402;FGF signaling pathway#P00021>ERK1-2#P00627;EGF receptor signaling pathway#P00018>ERK1-2#P00543;Angiogenesis#P00005>Erk#P00203;Toll receptor signaling pathway#P00054>ERK2#P01356;Gonadotropin-releasing hormone receptor pathway#P06664>ERK1/2#P06786;VEGF signaling pathway#P00056>Erk#P01407 MONDO|Ensembl=ENSMODG00000029344.2|UniProtKB=K7E4I2 K7E4I2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010447.3|UniProtKB=F7DM55 F7DM55 PTHR15002:SF0 RIBOSOMAL BIOGENESIS PROTEIN LAS1L RIBOSOMAL BIOGENESIS PROTEIN LAS1L catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000010323.3|UniProtKB=F6S9L4 F6S9L4 LOC100028371 PTHR26451:SF869 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 530-RELATED binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000014523.3|UniProtKB=F7ERN2 F7ERN2 EXOSC6 PTHR11953:SF2 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT MTR3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;snRNA 3'-end processing#GO:0034472;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;snRNA metabolic process#GO:0016073;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nuclear mRNA surveillance#GO:0071028;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;snRNA processing#GO:0016180;regulation of gene expression#GO:0010468 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 exoribonuclease#PC00099;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000008363.4|UniProtKB=F7EJN2 F7EJN2 CFAP52 PTHR13720:SF14 WD-40 REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 52 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000028952.2|UniProtKB=K7DZC1 K7DZC1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000023495.1|UniProtKB=F7EH45 F7EH45 TSSK1B PTHR24343:SF76 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 spermatid development#GO:0007286;sexual reproduction#GO:0019953;spermatid differentiation#GO:0048515;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;cellular process#GO:0009987;male gamete generation#GO:0048232 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000019612.4|UniProtKB=F6Y6Y1 F6Y6Y1 IPO11 PTHR10997:SF7 IMPORTIN-7, 8, 11 IMPORTIN-11 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle envelope#GO:0031967;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 MONDO|Ensembl=ENSMODG00000037791.1|UniProtKB=K7DYR5 K7DYR5 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000004609.3|UniProtKB=F6VX44 F6VX44 PRR7 PTHR16209:SF3 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 PROLINE-RICH PROTEIN 7 synaptic signaling#GO:0099536;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 cell junction#GO:0030054;membraneless organelle#GO:0043228;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;postsynapse#GO:0098794 MONDO|Ensembl=ENSMODG00000019001.4|UniProtKB=F7CP86 F7CP86 PPP2CB PTHR45619:SF44 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT BETA ISOFORM catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cellular process#GO:0009987 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195;protein modifying enzyme#PC00260 p53 pathway feedback loops 2#P04398>PP2A-C#P04659;FGF signaling pathway#P00021>PP2A#P00629;Wnt signaling pathway#P00057>PP2A#P01438;p53 pathway by glucose deprivation#P04397>PP2A-C#P04643;p53 pathway#P00059>PP2A#P04630;EGF receptor signaling pathway#P00018>PP2A#P00547 MONDO|Ensembl=ENSMODG00000012930.4|UniProtKB=A0A5F8GU99 A0A5F8GU99 ADSL PTHR43172:SF1 ADENYLOSUCCINATE LYASE ADENYLOSUCCINATE LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;organophosphate biosynthetic process#GO:0090407 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lyase#PC00144 De novo purine biosynthesis#P02738>Adenosuccinate lyase#P02901;De novo purine biosynthesis#P02738>5-Phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole lyase#P02892 MONDO|Ensembl=ENSMODG00000014765.4|UniProtKB=A0A5F8H5R6 A0A5F8H5R6 SATB1 PTHR15116:SF14 DNA-BINDING PROTEIN SATB FAMILY MEMBER DNA-BINDING PROTEIN SATB1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000016959.4|UniProtKB=F6V5I1 F6V5I1 LAMTOR2 PTHR13323:SF4 LATE ENDOSOMAL/LYSOSOMAL MP1 INTERACTING PROTEIN RAGULATOR COMPLEX PROTEIN LAMTOR2 protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of TORC1 signaling#GO:1904263;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to acid chemical#GO:0001101;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 membrane#GO:0016020;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;membrane protein complex#GO:0098796;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000005234.4|UniProtKB=F6ZCE4 F6ZCE4 CIITA PTHR47189:SF1 MHC CLASS II TRANSACTIVATOR MHC CLASS II TRANSACTIVATOR regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 MONDO|Ensembl=ENSMODG00000002167.4|UniProtKB=F6YEF8 F6YEF8 LGMN PTHR12000:SF57 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule catabolic process#GO:0009057;biosynthetic process#GO:0009058;catabolic process#GO:0009056;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000042305.1|UniProtKB=A0A5F8HHW3 A0A5F8HHW3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000011908.4|UniProtKB=F7EGL9 F7EGL9 TMEFF2 PTHR10913:SF80 FOLLISTATIN-RELATED TOMOREGULIN-2 developmental process#GO:0032502;cellular process#GO:0009987;cell differentiation#GO:0030154;cellular developmental process#GO:0048869 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000020352.4|UniProtKB=F7FKB2 F7FKB2 SLC1A3 PTHR11958:SF24 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 1 monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:monoatomic cation symporter activity#GO:0015294;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;acidic amino acid transmembrane transporter activity#GO:0015172;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943 establishment of localization#GO:0051234;import into cell#GO:0098657;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810;carboxylic acid transport#GO:0046942;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;amino acid transport#GO:0006865;L-glutamate transmembrane transport#GO:0015813;dicarboxylic acid transport#GO:0006835;L-amino acid transport#GO:0015807;aspartate transmembrane transport#GO:0015810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;L-glutamate import#GO:0051938;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036;Ionotropic glutamate receptor pathway#P00037>EAAT#P01011 MONDO|Ensembl=ENSMODG00000028977.2|UniProtKB=K7E3B0 K7E3B0 PTHR46841:SF10 OX-2 MEMBRANE GLYCOPROTEIN CD200 MOLECULE LIKE 1-RELATED cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515 regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;cell adhesion#GO:0007155;negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;heterotypic cell-cell adhesion#GO:0034113;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 neuron projection#GO:0043005;cell body#GO:0044297;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424 MONDO|Ensembl=ENSMODG00000002830.4|UniProtKB=F7EIX3 F7EIX3 CHMP4B PTHR22761:SF4 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 4B establishment of localization in cell#GO:0051649;multivesicular body sorting pathway#GO:0071985;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;nuclear envelope organization#GO:0006998;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;nucleus organization#GO:0006997;membrane assembly#GO:0071709;cellular component organization#GO:0016043;late endosome to vacuole transport#GO:0045324;localization#GO:0051179;cellular localization#GO:0051641 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;cytoplasmic side of plasma membrane#GO:0009898;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasmic side of membrane#GO:0098562;nuclear envelope#GO:0005635;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle membrane#GO:0012506;membrane#GO:0016020 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000018020.3|UniProtKB=F7AJX0 F7AJX0 MTRES1 PTHR13633:SF3 MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000006176.3|UniProtKB=F7B5F0 F7B5F0 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000041356.1|UniProtKB=A0A5F8GZX0 A0A5F8GZX0 LOC100028321 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000043352.1|UniProtKB=A0A5F8HJR3 A0A5F8HJR3 VN2R618 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001896.4|UniProtKB=F6WGB2 F6WGB2 GABBR2 PTHR10519:SF74 GABA-B RECEPTOR GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;regulation of biological process#GO:0050789;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;signaling receptor complex#GO:0043235 G-protein coupled receptor#PC00021 GABA-B receptor II signaling#P05731>GABA-B receptor#P05756 MONDO|Ensembl=ENSMODG00000024050.1|UniProtKB=F7GH07 F7GH07 IMMP2L PTHR46041:SF2 MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2 MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2 catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein localization to mitochondrion#GO:0070585;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endopeptidase complex#GO:1905369;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;peptidase complex#GO:1905368;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 protease#PC00190 MONDO|Ensembl=ENSMODG00000046847.1|UniProtKB=F6TZN1 F6TZN1 PTHR46467:SF1 TETHER CONTAINING UBX DOMAIN FOR GLUT4 TETHER CONTAINING UBX DOMAIN FOR GLUT4 intracellular protein transport#GO:0006886;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular transport#GO:0046907;glucose homeostasis#GO:0042593;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;carbohydrate homeostasis#GO:0033500;homeostatic process#GO:0042592 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle#GO:0031982;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000027853.2|UniProtKB=K7E1F5 K7E1F5 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000006363.5|UniProtKB=A0A5F8GTY6 A0A5F8GTY6 DIAPH3 PTHR45691:SF9 PROTEIN DIAPHANOUS PROTEIN DIAPHANOUS HOMOLOG 3 protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;actin filament polymerization#GO:0030041;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;actin filament#GO:0005884 cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>mDia#P00510 MONDO|Ensembl=ENSMODG00000023794.3|UniProtKB=F6VTF1 F6VTF1 LOC100009874 PTHR11927:SF9 GALACTOSIDE 2-L-FUCOSYLTRANSFERASE L-FUCOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000003163.2|UniProtKB=F6WDJ4 F6WDJ4 PTHR26453:SF636 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2B8 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007007.4|UniProtKB=F6XTY3 F6XTY3 NPR2 PTHR11920:SF509 GUANYLYL CYCLASE ATRIAL NATRIURETIC PEPTIDE RECEPTOR 2 molecular transducer activity#GO:0060089;lyase activity#GO:0016829;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;peptide receptor activity#GO:0001653;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;ribose phosphate biosynthetic process#GO:0046390;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 lyase#PC00144;guanylate cyclase#PC00114 Gonadotropin-releasing hormone receptor pathway#P06664>Npr2#P06796 MONDO|Ensembl=ENSMODG00000004367.4|UniProtKB=F6W9V6 F6W9V6 ASB10 PTHR24178:SF52 MOLTING PROTEIN MLT-4 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN macromolecule localization#GO:0033036;localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;protein localization to cilium#GO:0061512 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 MONDO|Ensembl=ENSMODG00000025337.2|UniProtKB=F7A0G0 F7A0G0 HPDL PTHR11959:SF10 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE-LIKE PROTEIN oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000020434.4|UniProtKB=F7AR74 F7AR74 MALT1 PTHR22576:SF40 MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1 catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;positive regulation of signaling#GO:0023056;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;lymphocyte activation#GO:0046649;antigen receptor-mediated signaling pathway#GO:0050851;defense response to other organism#GO:0098542;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;immune response-activating signaling pathway#GO:0002757;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;B cell activation#GO:0042113;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of signal transduction#GO:0009967;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;cell activation#GO:0001775;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of canonical NF-kappaB signal transduction#GO:0043122;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;T cell receptor signaling pathway#GO:0050852;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000027838.2|UniProtKB=A0A5F8G5H7 A0A5F8G5H7 TMIGD2 PTHR14334:SF3 B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN CONTAINING 2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 immune system process#GO:0002376;leukocyte differentiation#GO:0002521;regulation of biological process#GO:0050789;mononuclear cell differentiation#GO:1903131;immune response-regulating signaling pathway#GO:0002764;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;cell development#GO:0048468;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;B cell activation#GO:0042113;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;B cell receptor signaling pathway#GO:0050853;cellular process#GO:0009987;lymphocyte activation#GO:0046649;antigen receptor-mediated signaling pathway#GO:0050851;regulation of immune response#GO:0050776;lymphocyte differentiation#GO:0030098;cell activation#GO:0001775;cell communication#GO:0007154;anatomical structure development#GO:0048856;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;developmental process#GO:0032502;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cellular developmental process#GO:0048869;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;hemopoiesis#GO:0030097 membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;side of membrane#GO:0098552 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000013392.4|UniProtKB=A0A5F8GKR7 A0A5F8GKR7 PRKAR2A PTHR11635:SF153 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE II-ALPHA REGULATORY SUBUNIT enzyme inhibitor activity#GO:0004857;protein kinase inhibitor activity#GO:0004860;nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;protein kinase A binding#GO:0051018;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;kinase inhibitor activity#GO:0019210;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 cytosol#GO:0005829;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Enkephalin release#P05913>PKA#P05972;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;GABA-B receptor II signaling#P05731>PKA#P05752;Endothelin signaling pathway#P00019>PKA#P00570;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Hedgehog signaling pathway#P00025>PKA#P00682;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075 MONDO|Ensembl=ENSMODG00000047356.1|UniProtKB=A0A5F8HGJ4 A0A5F8HGJ4 LOC100025735 PTHR12960:SF0 GLE-1-RELATED MRNA EXPORT FACTOR GLE1 lipid binding#GO:0008289;protein binding#GO:0005515;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;alcohol binding#GO:0043178;translation initiation factor binding#GO:0031369;phospholipid binding#GO:0005543 poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;localization#GO:0051179;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 translation factor#PC00223 MONDO|Ensembl=ENSMODG00000006154.3|UniProtKB=F7BSL0 F7BSL0 NKX2-5 PTHR24340:SF28 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000039280.1|UniProtKB=A0A5F8GF99 A0A5F8GF99 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000018031.4|UniProtKB=F6ZWJ1 F6ZWJ1 PREP PTHR42881:SF2 PROLYL ENDOPEPTIDASE PROLYL ENDOPEPTIDASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 Vasopressin synthesis#P04395>Endo Peptidase#P04596 MONDO|Ensembl=ENSMODG00000010180.4|UniProtKB=F6SUP3 F6SUP3 ACTN1 PTHR11915:SF434 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;membrane#GO:0016020;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;actomyosin#GO:0042641;cell periphery#GO:0071944;cell junction#GO:0030054;sarcomere#GO:0030017;membraneless organelle#GO:0043228;stress fiber#GO:0001725;cytoskeleton#GO:0005856;I band#GO:0031674;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;myofibril#GO:0030016;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 MONDO|Ensembl=ENSMODG00000005221.3|UniProtKB=F6ZDC9 F6ZDC9 PTHR19918:SF1 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED FIZZY-RELATED PROTEIN HOMOLOG enzyme regulator activity#GO:0030234;protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme activator activity#GO:0008047 protein metabolic process#GO:0019538;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;primary metabolic process#GO:0044238;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;positive regulation of metabolic process#GO:0009893;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000008220.4|UniProtKB=F6ZYD3 F6ZYD3 LOC100027956 PTHR10985:SF104 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;neuron differentiation#GO:0030182;negative regulation of RNA metabolic process#GO:0051253;cell surface receptor signaling pathway#GO:0007166;negative regulation of RNA biosynthetic process#GO:1902679;anterior/posterior pattern specification#GO:0009952;multicellular organism development#GO:0007275;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;pattern specification process#GO:0007389;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;cellular developmental process#GO:0048869;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000017183.3|UniProtKB=F6XYI2 F6XYI2 NRBF2 PTHR14964:SF2 NUCLEAR RECEPTOR BINDING FACTOR 2 NUCLEAR RECEPTOR-BINDING FACTOR 2 metabolic process#GO:0008152;autophagy#GO:0006914;cellular process#GO:0009987;catabolic process#GO:0009056;process utilizing autophagic mechanism#GO:0061919 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000038232.1|UniProtKB=A0A5F8HEG5 A0A5F8HEG5 PTHR10681:SF111 THIOREDOXIN PEROXIDASE PEROXIREDOXIN-1 antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 hydrogen peroxide metabolic process#GO:0042743;homeostatic process#GO:0042592;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;cellular detoxification#GO:1990748;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular oxidant detoxification#GO:0098869;response to stress#GO:0006950;cellular homeostasis#GO:0019725;response to reactive oxygen species#GO:0000302;cell redox homeostasis#GO:0045454;superoxide metabolic process#GO:0006801;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176;peroxidase#PC00180 MONDO|Ensembl=ENSMODG00000027852.2|UniProtKB=K7E5C1 K7E5C1 SBK3 PTHR24363:SF6 SERINE/THREONINE PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000005799.3|UniProtKB=H9H831 H9H831 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000007499.3|UniProtKB=F6YXA4 F6YXA4 TRIM16 PTHR25465:SF10 B-BOX DOMAIN CONTAINING TRIPARTITE MOTIF-CONTAINING PROTEIN 16 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000013354.2|UniProtKB=F7DTY4 F7DTY4 IMPDH2 PTHR11911:SF121 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 De novo purine biosynthesis#P02738>IMP dehydrogenase#P02895 MONDO|Ensembl=ENSMODG00000001545.3|UniProtKB=A0A5F8GWH3 A0A5F8GWH3 PRXL2A PTHR28630:SF35 FAMILY NOT NAMED PEROXIREDOXIN-LIKE 2A cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000006002.5|UniProtKB=F6SKX5 F6SKX5 PTHR14649:SF1 ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1C ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1C MONDO|Ensembl=ENSMODG00000040142.1|UniProtKB=A0A5F8G354 A0A5F8G354 PTHR24377:SF878 IP01015P-RELATED ZINC FINGER PROTEIN 670 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000000628.4|UniProtKB=F6TAG2 F6TAG2 SYT6 PTHR10024:SF45 SYNAPTOTAGMIN SYNAPTOTAGMIN-6 SNARE binding#GO:0000149;binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;protein binding#GO:0005515 trans-synaptic signaling#GO:0099537;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;cell communication#GO:0007154;regulation of secretion#GO:0051046;localization#GO:0051179;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;transport#GO:0006810;regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of localization#GO:0051234;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 MONDO|Ensembl=ENSMODG00000021126.4|UniProtKB=F6QXH0 F6QXH0 DMD PTHR12268:SF25 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROPHIN muscle organ development#GO:0007517;regulation of system process#GO:0044057;neuron differentiation#GO:0030182;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;cellular developmental process#GO:0048869;animal organ development#GO:0048513;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;skeletal muscle tissue development#GO:0007519;cellular process#GO:0009987;multicellular organismal process#GO:0032501;tissue development#GO:0009888;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;muscle tissue development#GO:0060537;system development#GO:0048731;muscle cell development#GO:0055001;regulation of muscle system process#GO:0090257;regulation of biological process#GO:0050789;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;cell differentiation#GO:0030154;cell development#GO:0048468 cell junction#GO:0030054;sarcolemma#GO:0042383;protein-containing complex#GO:0032991;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane protein complex#GO:0098796;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000009807.3|UniProtKB=A0A5F8GK02 A0A5F8GK02 PTHR10462:SF26 GLYCOSYLTRANSFERASE-RELATED N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000011568.4|UniProtKB=F6QBG9 F6QBG9 ICE2 PTHR14633:SF3 LITTLE ELONGATION COMPLEX SUBUNIT 2 LITTLE ELONGATION COMPLEX SUBUNIT 2 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;DNA-templated transcription#GO:0006351;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;snRNA transcription by RNA polymerase III#GO:0042796;snRNA metabolic process#GO:0016073;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;transcription by RNA polymerase II#GO:0006366;snRNA transcription#GO:0009301;transcription by RNA polymerase III#GO:0006383;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 MONDO|Ensembl=ENSMODG00000009238.4|UniProtKB=F7EDR8 F7EDR8 HMGB1 PTHR48112:SF12 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP BOX 1, PSEUDOGENE 34 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 p53 pathway#P00059>HMG1#P04619 MONDO|Ensembl=ENSMODG00000004839.4|UniProtKB=F6U5K0 F6U5K0 BLNK PTHR14098:SF3 SH2 DOMAIN CONTAINING PROTEIN B-CELL LINKER PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune system process#GO:0002376;regulation of immune response#GO:0050776;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;intracellular signal transduction#GO:0035556;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;B cell receptor signaling pathway#GO:0050853;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;antigen receptor-mediated signaling pathway#GO:0050851;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 B cell activation#P00010>BLNK#P00394 MONDO|Ensembl=ENSMODG00000005024.2|UniProtKB=A0A5F8HFK5 A0A5F8HFK5 ZNHIT1 PTHR13093:SF0 ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 1 ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;Swr1 complex#GO:0000812;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000012563.4|UniProtKB=F6PLE0 F6PLE0 ABITRAM PTHR13651:SF1 PROTEIN ABITRAM PROTEIN ABITRAM binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin monomer binding#GO:0003785;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 animal gross anatomical part developmental process#GO:0160108;regulation of actin filament length#GO:0030832;generation of neurons#GO:0048699;dendrite development#GO:0016358;neuron development#GO:0048666;regulation of biological quality#GO:0065008;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;regulation of anatomical structure size#GO:0090066;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of actin cytoskeleton organization#GO:0032956;nervous system development#GO:0007399;anatomical structure development#GO:0048856;regulation of cell projection assembly#GO:0060491;system development#GO:0048731;dendrite morphogenesis#GO:0048813;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of plasma membrane bounded cell projection organization#GO:0120035;neurogenesis#GO:0022008;regulation of filopodium assembly#GO:0051489;regulation of actin filament organization#GO:0110053;multicellular organismal process#GO:0032501;regulation of actin filament polymerization#GO:0030833;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;filopodium#GO:0030175;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;lamellipodium#GO:0030027;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;cell leading edge#GO:0031252;neuron projection#GO:0043005;nucleus#GO:0005634;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000018260.4|UniProtKB=F6TRL6 F6TRL6 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009089.4|UniProtKB=F7FQN8 F7FQN8 RAPGEF4 PTHR23113:SF175 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000003483.4|UniProtKB=F7DBK8 F7DBK8 FKBP8 PTHR46512:SF3 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP8 macromolecule metabolic process#GO:0043170;positive regulation of BMP signaling pathway#GO:0030513;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;gene expression#GO:0010467;protein maturation#GO:0051604;positive regulation of response to stimulus#GO:0048584;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of signal transduction#GO:0009966;regulation of BMP signaling pathway#GO:0030510;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;protein folding#GO:0006457;primary metabolic process#GO:0044238;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 membrane#GO:0016020;organelle envelope#GO:0031967;cytosol#GO:0005829;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000000317.4|UniProtKB=F6VUY6 F6VUY6 TPGS2 PTHR31854:SF2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 2 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000014192.4|UniProtKB=F6TRE7 F6TRE7 TMPRSS5 PTHR24253:SF70 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 5 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000037072.1|UniProtKB=A0A5F8GZ67 A0A5F8GZ67 PTHR24270:SF62 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED CD320 ANTIGEN cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219;apolipoprotein#PC00052 MONDO|Ensembl=ENSMODG00000004065.4|UniProtKB=F6VWD0 F6VWD0 DPYD PTHR43073:SF5 DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)] DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)] purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;primary metabolic process#GO:0044238;pyrimidine nucleobase catabolic process#GO:0006208;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;pyrimidine nucleobase metabolic process#GO:0006206 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 oxidoreductase#PC00176;dehydrogenase#PC00092 Pyrimidine Metabolism#P02771>Dihydrouracil Dehydrogenase#P03128 MONDO|Ensembl=ENSMODG00000025648.3|UniProtKB=F6XE79 F6XE79 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000020063.4|UniProtKB=F7F0P9 F7F0P9 OR5AR1 PTHR26452:SF315 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AR1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013084.4|UniProtKB=F7FB58 F7FB58 NFYA PTHR12632:SF122 TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT ALPHA DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 MONDO|Ensembl=ENSMODG00000013083.4|UniProtKB=F7FB63 F7FB63 L3MBTL2 PTHR12247:SF64 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000020743.4|UniProtKB=F7A018 F7A018 PTHR24253:SF52 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 11C hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000008322.4|UniProtKB=F7FGA4 F7FGA4 PGAP2 PTHR12892:SF11 FGF RECEPTOR ACTIVATING PROTEIN 1 ACYLTRANSFERASE PGAP2 biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538 membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000014806.4|UniProtKB=F7A3N9 F7A3N9 KAT2B PTHR45750:SF2 GH11602P HISTONE ACETYLTRANSFERASE KAT2B N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;protein N-acyltransferase activity#GO:0140186;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;chromatin organization#GO:0006325;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of RNA metabolic process#GO:0051254;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891 chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;SAGA-type complex#GO:0070461;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535 p53 pathway#P00059>PCAF#P04629;Gonadotropin-releasing hormone receptor pathway#P06664>Pcaf#P06715 MONDO|Ensembl=ENSMODG00000011561.4|UniProtKB=A0A5F8GV14 A0A5F8GV14 SLC25A39 PTHR45760:SF1 FI19922P1-RELATED MITOCHONDRIAL GLUTATHIONE TRANSPORTER SLC25A39 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000025255.2|UniProtKB=A0A5F8HG94 A0A5F8HG94 PTHR23220:SF118 INTEGRIN ALPHA INTEGRIN SUBUNIT ALPHA D signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell surface receptor signaling pathway#GO:0007166;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 integrin#PC00126;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000012391.4|UniProtKB=F6VB36 F6VB36 SERPINA1 PTHR11461:SF165 SERINE PROTEASE INHIBITOR, SERPIN ALPHA-1-ANTITRYPSIN enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 Blood coagulation#P00011>alpha1-antitrypsin#P00421 MONDO|Ensembl=ENSMODG00000015310.4|UniProtKB=F6XZ29 F6XZ29 SCRN1 PTHR12994:SF7 SECERNIN SECERNIN-1 MONDO|Ensembl=ENSMODG00000003772.4|UniProtKB=A0A5F8GC39 A0A5F8GC39 PRRC2C PTHR14038:SF6 BAT2 HLA-B-ASSOCIATED TRANSCRIPT 2 PROTEIN PRRC2C binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cytoplasmic stress granule assembly#GO:0034063;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000006468.4|UniProtKB=F7FGA9 F7FGA9 PTHR14102:SF12 PAR-6-RELATED CDNA SEQUENCE BC034090 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 establishment or maintenance of cell polarity#GO:0007163;cell-cell junction organization#GO:0045216;cell-cell junction maintenance#GO:0045217;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cell cycle process#GO:0022402;cellular process#GO:0009987;centrosome cycle#GO:0007098;cell junction organization#GO:0034330;cytoskeleton organization#GO:0007010 nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;apical part of cell#GO:0045177;transferase complex#GO:1990234;protein kinase complex#GO:1902911;cell cortex#GO:0005938;apical plasma membrane#GO:0016324;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000018659.4|UniProtKB=F7AFC4 F7AFC4 WDR33 PTHR22836:SF0 WD40 REPEAT PROTEIN PRE-MRNA 3' END PROCESSING PROTEIN WDR33 cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000013921.3|UniProtKB=F6SV98 F6SV98 PTHR10867:SF32 NNMT/PNMT/TEMT FAMILY MEMBER MGC107884 PROTEIN methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;N-methyltransferase activity#GO:0008170 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 MONDO|Ensembl=ENSMODG00000043525.1|UniProtKB=K7DZN7 K7DZN7 PTHR46890:SF56 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED OS06G0484800 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000021024.4|UniProtKB=F6QYZ8 F6QYZ8 WDR4 PTHR16288:SF0 WD40 REPEAT PROTEIN 4 TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT WDR4 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleus#GO:0005634;cytosol#GO:0005829 RNA processing factor#PC00147;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000046726.1|UniProtKB=A0A5F8HBZ3 A0A5F8HBZ3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000023305.3|UniProtKB=F6VAZ1 F6VAZ1 PIERCE1 PTHR20899:SF1 PIERCE HOMOLOG PIERCER OF MICROTUBULE WALL 1 PROTEIN MONDO|Ensembl=ENSMODG00000011634.4|UniProtKB=A0A5F8G1Y5 A0A5F8G1Y5 CNIH1 PTHR12290:SF10 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 1 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000019403.4|UniProtKB=F6SZF3 F6SZF3 CEMIP PTHR15535:SF15 TRANSMEMBRANE PROTEIN 2-RELATED CELL MIGRATION-INDUCING AND HYALURONAN-BINDING PROTEIN hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;glycosaminoglycan catabolic process#GO:0006027;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000044916.1|UniProtKB=F6YJI8 F6YJI8 PTHR26452:SF812 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AC2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000004424.2|UniProtKB=A0A5F8GYU2 A0A5F8GYU2 PTHR11937:SF175 ACTIN ACTIN-RELATED PROTEIN 3 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198;cytoskeletal protein binding#GO:0008092 cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cortical actin cytoskeleton organization#GO:0030866;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;organelle organization#GO:0006996;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000002181.4|UniProtKB=F7GEC6 F7GEC6 GAA PTHR22762:SF92 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;alpha-glucosidase activity#GO:0090599;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;glucosidase activity#GO:0015926;catalytic activity#GO:0003824 lytic vacuole organization#GO:0080171;generation of precursor metabolites and energy#GO:0006091;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;energy derivation by oxidation of organic compounds#GO:0015980;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;lysosome organization#GO:0007040;glycogen catabolic process#GO:0005980;organelle organization#GO:0006996;energy reserve metabolic process#GO:0006112;vacuole organization#GO:0007033;carbohydrate catabolic process#GO:0016052;polysaccharide catabolic process#GO:0000272;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;glycogen metabolic process#GO:0005977;glucan catabolic process#GO:0009251;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;catabolic process#GO:0009056 glucosidase#PC00108 MONDO|Ensembl=ENSMODG00000045061.1|UniProtKB=A0A5F8GWU3 A0A5F8GWU3 CLEC1B PTHR46490:SF2 C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 1 MEMBER B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 developmental process#GO:0032502;anatomical structure formation involved in morphogenesis#GO:0048646;cellular developmental process#GO:0048869;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;hemopoiesis#GO:0030097;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;regulation of cellular process#GO:0050794;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000015054.4|UniProtKB=F7FUN5 F7FUN5 TYRP1 PTHR11474:SF3 TYROSINASE FAMILY MEMBER 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACID OXIDASE monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 developmental process#GO:0032502;pigmentation#GO:0043473;melanosome organization#GO:0032438;vesicle organization#GO:0016050;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental pigmentation#GO:0048066;cellular process#GO:0009987;melanocyte differentiation#GO:0030318;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular pigmentation#GO:0033059;cell differentiation#GO:0030154 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;melanosome#GO:0042470;intracellular vesicle#GO:0097708;vesicle#GO:0031982 oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000023092.3|UniProtKB=F6ZPS1 F6ZPS1 TUBB3 PTHR11588:SF43 TUBULIN TUBULIN BETA-3 CHAIN ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;system development#GO:0048731;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 tubulin#PC00228;cytoskeletal protein#PC00085 Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780 MONDO|Ensembl=ENSMODG00000038086.1|UniProtKB=F7EIN0 F7EIN0 LOC100010102 PTHR11783:SF14 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1B1 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000005568.3|UniProtKB=F7F3M5 F7F3M5 VASH1 PTHR15750:SF5 VASOHIBIN-1-LIKE ISOFORM X2 TUBULINYL-TYR CARBOXYPEPTIDASE 1 regulation of vasculature development#GO:1901342;regulation of angiogenesis#GO:0045765;regulation of anatomical structure morphogenesis#GO:0022603;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of multicellular organismal process#GO:0051239 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000018096.4|UniProtKB=F7FFS3 F7FFS3 TAGLN3 PTHR47385:SF10 CALPONIN TRANSGELIN-3 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000042452.1|UniProtKB=K7E5J2 K7E5J2 PTHR19367:SF24 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 8-4 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000007313.2|UniProtKB=F7EXZ1 F7EXZ1 TMEM43 PTHR13416:SF2 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 43 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000016329.4|UniProtKB=F7FL33 F7FL33 ALS2 PTHR46089:SF3 ALSIN HOMOLOG ALSIN binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025 MONDO|Ensembl=ENSMODG00000002547.4|UniProtKB=F7ALU3 F7ALU3 CHAT PTHR22589:SF14 CARNITINE O-ACYLTRANSFERASE CHOLINE O-ACETYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cell communication#GO:0007154;neuromuscular synaptic transmission#GO:0007274;trans-synaptic signaling#GO:0099537;metabolic process#GO:0008152;anterograde trans-synaptic signaling#GO:0098916;biosynthetic process#GO:0009058;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of biological process#GO:0050789 neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 MONDO|Ensembl=ENSMODG00000017729.4|UniProtKB=F7ELE8 F7ELE8 PTHR12786:SF2 SPLICING FACTOR SF3A-RELATED SPLICING FACTOR 3A SUBUNIT 3 binding#GO:0005488;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398 small nuclear ribonucleoprotein complex#GO:0030532;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;U2 snRNP#GO:0005686;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;Sm-like protein family complex#GO:0120114;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000012408.4|UniProtKB=F6PMN5 F6PMN5 KYAT3 PTHR43807:SF6 FI04487P KYNURENINE--OXOGLUTARATE TRANSAMINASE 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220;transaminase#PC00216 MONDO|Ensembl=ENSMODG00000007886.3|UniProtKB=F6ZGH1 F6ZGH1 COQ8B PTHR43851:SF4 FAMILY NOT NAMED ATYPICAL KINASE COQ8B, MITOCHONDRIAL biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ketone metabolic process#GO:0042180;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152 MONDO|Ensembl=ENSMODG00000050682.1|UniProtKB=A0A5F8G8U2 A0A5F8G8U2 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000001988.3|UniProtKB=A0A5F8H590 A0A5F8H590 CYTH1 PTHR10663:SF340 GUANYL-NUCLEOTIDE EXCHANGE FACTOR CYTOHESIN-1 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000016213.4|UniProtKB=F7FLS0 F7FLS0 PARD3B PTHR16484:SF4 PARTITIONING DEFECTIVE 3 RELATED PARTITIONING DEFECTIVE 3 HOMOLOG B ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;binding#GO:0005488;small molecule binding#GO:0036094 microtubule cytoskeleton organization#GO:0000226;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;establishment or maintenance of bipolar cell polarity#GO:0061245;cell adhesion#GO:0007155;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment or maintenance of cell polarity#GO:0007163;establishment of cell polarity#GO:0030010;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996 cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cell cortex#GO:0005938;cell-cell junction#GO:0005911;membrane#GO:0016020;apical plasma membrane#GO:0016324;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell junction#GO:0030054;apical part of cell#GO:0045177;apical junction complex#GO:0043296 MONDO|Ensembl=ENSMODG00000017302.4|UniProtKB=F6S4L6 F6S4L6 DNA2 PTHR10887:SF433 DNA2/NAM7 HELICASE FAMILY DNA REPLICATION ATP-DEPENDENT HELICASE_NUCLEASE DNA2 nucleic acid binding#GO:0003676;binding#GO:0005488;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;RNA binding#GO:0003723;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097 cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA helicase#PC00032 DNA replication#P00017>Hel#P00532 MONDO|Ensembl=ENSMODG00000014976.4|UniProtKB=A0A5F8HKR6 A0A5F8HKR6 EVI5L PTHR22957:SF254 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN EVI5-LIKE PROTEIN enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000003112.4|UniProtKB=F6S3H0 F6S3H0 ZEB2 PTHR24391:SF11 HISTONE H4 TRANSCRIPTION FACTOR-RELATED ZINC FINGER E-BOX-BINDING HOMEOBOX 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000045022.1|UniProtKB=A0A5F8G718 A0A5F8G718 VN2R571 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009998.4|UniProtKB=F6US93 F6US93 RDH11 PTHR24320:SF306 RETINOL DEHYDROGENASE RETINOL DEHYDROGENASE 11 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;olefinic compound metabolic process#GO:0120254;retinol metabolic process#GO:0042572;small molecule metabolic process#GO:0044281;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 oxidoreductase#PC00176;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000020406.4|UniProtKB=A0A5F8H0S9 A0A5F8H0S9 LGR5 PTHR24372:SF71 GLYCOPROTEIN HORMONE RECEPTOR LEUCINE-RICH REPEAT-CONTAINING G PROTEIN-COUPLED RECEPTOR 5 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;positive regulation of signaling#GO:0023056;hormone-mediated signaling pathway#GO:0009755;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to hormone#GO:0009725;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of Wnt signaling pathway#GO:0030177;response to chemical#GO:0042221;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;positive regulation of canonical Wnt signaling pathway#GO:0090263 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000009464.4|UniProtKB=F7FZD5 F7FZD5 CHN1 PTHR46075:SF1 CHIMERIN FAMILY MEMBER N-CHIMAERIN molecular function activator activity#GO:0140677;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;axon guidance#GO:0007411;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154 MONDO|Ensembl=ENSMODG00000017750.3|UniProtKB=F7E541 F7E541 YRDC PTHR17490:SF16 SUA5 THREONYLCARBAMOYL-AMP SYNTHASE tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000024678.2|UniProtKB=F7G2B2 F7G2B2 UBE2G1 PTHR24067:SF3 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000025001.3|UniProtKB=F7DWD6 F7DWD6 DZIP1 PTHR21502:SF5 ZINC FINGER PROTEIN DZIP1 CILIUM ASSEMBLY PROTEIN DZIP1 protein-containing complex binding#GO:0044877;protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000017732.4|UniProtKB=F7EL84 F7EL84 SMPDL3A PTHR10340:SF24 SPHINGOMYELIN PHOSPHODIESTERASE CYCLIC GMP-AMP PHOSPHODIESTERASE SMPDL3A hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000014760.4|UniProtKB=F7GGY5 F7GGY5 DNAJC7 PTHR44200:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 7 DNAJ HOMOLOG SUBFAMILY C MEMBER 7 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000020109.4|UniProtKB=F7EAG8 F7EAG8 FAM81B PTHR22420:SF5 PROTEIN FAM81A PROTEIN FAM81B MONDO|Ensembl=ENSMODG00000006673.4|UniProtKB=F6RDG8 F6RDG8 CPEB3 PTHR12566:SF7 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 3 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;translation factor activity#GO:0180051;translation regulator activity#GO:0045182;mRNA 3'-UTR binding#GO:0003730 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;system process#GO:0003008;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of synapse structure or activity#GO:0050803;cognition#GO:0050890;regulation of cell junction assembly#GO:1901888;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of biological quality#GO:0065008;nervous system process#GO:0050877;regulation of synapse organization#GO:0050807;negative regulation of translation#GO:0017148;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789 cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;nucleus#GO:0005634;neuron projection#GO:0043005 mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000028024.2|UniProtKB=K7E1J5 K7E1J5 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000019022.3|UniProtKB=F7BLL5 F7BLL5 CNPY3 PTHR15382:SF2 CTG4A-RELATED PROTEIN CANOPY HOMOLOG 3 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 MONDO|Ensembl=ENSMODG00000017904.4|UniProtKB=F7FG70 F7FG70 TFAP2E PTHR10812:SF13 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-EPSILON sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of cell population proliferation#GO:0042127;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000038977.1|UniProtKB=A0A5F8GAU4 A0A5F8GAU4 PTHR34639:SF1 PROTEIN FLATTOP PROTEIN FLATTOP cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cilium#GO:0005929;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000015629.4|UniProtKB=F7FEU0 F7FEU0 MCC PTHR23347:SF4 COLORECTAL MUTANT CANCER PROTEIN MCC PROTEIN -RELATED COLORECTAL MUTANT CANCER PROTEIN regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000013844.4|UniProtKB=F6X6M3 F6X6M3 SNAP47 PTHR19305:SF1 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 47 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484;protein binding#GO:0005515 cellular localization#GO:0051641;secretion by cell#GO:0032940;signaling#GO:0023052;export from cell#GO:0140352;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;exocytosis#GO:0006887;regulated exocytosis#GO:0045055;vesicle fusion to plasma membrane#GO:0099500;exocytic process#GO:0140029;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;neurotransmitter transport#GO:0006836;endomembrane system organization#GO:0010256;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;synaptic vesicle fusion to presynaptic active zone membrane#GO:0031629;anterograde trans-synaptic signaling#GO:0098916;vesicle fusion#GO:0006906;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;neurotransmitter secretion#GO:0007269;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic vesicle membrane organization#GO:0048499;membrane fusion#GO:0061025 cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150;SNARE protein#PC00034 MONDO|Ensembl=ENSMODG00000040016.1|UniProtKB=A0A5F8GPV0 A0A5F8GPV0 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000011333.3|UniProtKB=F6WI14 F6WI14 PTHR23349:SF57 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FACTOR IN THE GERMLINE ALPHA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000049037.1|UniProtKB=A0A5F8GWR1 A0A5F8GWR1 SIX1 PTHR10390:SF13 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000015447.3|UniProtKB=F6S429 F6S429 ZNF316 PTHR24408:SF54 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 316 sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000036999.1|UniProtKB=A0A5F8GHR1 A0A5F8GHR1 F2RL2 PTHR24232:SF0 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 3 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Blood coagulation#P00011>mPAR-3#P00452 MONDO|Ensembl=ENSMODG00000007365.3|UniProtKB=F7ADB3 F7ADB3 PPARA PTHR24082:SF197 NUCLEAR HORMONE RECEPTOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to hormone stimulus#GO:0032870;cellular response to chemical stimulus#GO:0070887;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;hormone-mediated signaling pathway#GO:0009755;negative regulation of DNA-templated transcription#GO:0045892;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;response to hormone#GO:0009725;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of lipid metabolic process#GO:0019216;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513 C4 zinc finger nuclear receptor#PC00169 Gonadotropin-releasing hormone receptor pathway#P06664>PPARalpha/gamma#P06744 MONDO|Ensembl=ENSMODG00000049518.1|UniProtKB=A0A5F8H8N5 A0A5F8H8N5 PTHR10010:SF23 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B phosphate transmembrane transporter activity#GO:0005315;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081 phosphate ion transport#GO:0006817;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;cellular homeostasis#GO:0019725;inorganic anion transport#GO:0015698;intracellular chemical homeostasis#GO:0055082 apical plasma membrane#GO:0016324;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;brush border#GO:0005903;organelle#GO:0043226;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical part of cell#GO:0045177;membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000021010.3|UniProtKB=A0A5F8G2H0 A0A5F8G2H0 JAM2 PTHR44663:SF2 JUNCTIONAL ADHESION MOLECULE B JUNCTIONAL ADHESION MOLECULE B cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000013632.3|UniProtKB=F6UVV3 F6UVV3 RCN3 PTHR10827:SF47 RETICULOCALBIN RETICULOCALBIN-3 ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000011493.3|UniProtKB=F6V2K5 F6V2K5 OR52B6 PTHR26450:SF32 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52B6 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016394.3|UniProtKB=F7E910 F7E910 PTHR10666:SF424 UBIQUITIN UBIQUITIN-RIBOSOMAL PROTEIN EL40 FUSION PROTEIN structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000038378.1|UniProtKB=A0A5F8G5W0 A0A5F8G5W0 RETREG1 PTHR28659:SF3 RETICULON-LIKE PROTEIN RETICULOPHAGY REGULATOR 1 catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;process utilizing autophagic mechanism#GO:0061919;biological regulation#GO:0065007;macroautophagy#GO:0016236;negative regulation of apoptotic process#GO:0043066;autophagy#GO:0006914;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;reticulophagy#GO:0061709;negative regulation of neuron apoptotic process#GO:0043524;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000006030.3|UniProtKB=F6ZUZ1 F6ZUZ1 LOC100029992 PTHR26451:SF233 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 4E1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000010599.3|UniProtKB=F7G8G1 F7G8G1 OSCAR PTHR11738:SF198 MHC CLASS I NK CELL RECEPTOR OSTEOCLAST-ASSOCIATED IMMUNOGLOBULIN-LIKE RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 developmental process#GO:0032502;cellular developmental process#GO:0048869;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;hemopoiesis#GO:0030097;cell communication#GO:0007154;anatomical structure development#GO:0048856;osteoclast differentiation#GO:0030316;leukocyte differentiation#GO:0002521;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell development#GO:0048468 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000020603.4|UniProtKB=F6ZBJ4 F6ZBJ4 LEF1 PTHR10373:SF11 TRANSCRIPTION FACTOR 7 FAMILY MEMBER LYMPHOID ENHANCER-BINDING FACTOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;Wnt signaling pathway#GO:0016055;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;RNA polymerase II transcription regulator complex#GO:0090575;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Cadherin signaling pathway#P00012>TCF/LEF#P00465;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Wnt signaling pathway#P00057>TCF#P01437 MONDO|Ensembl=ENSMODG00000008020.4|UniProtKB=F7CKZ6 F7CKZ6 PTHR28638:SF2 CELL CYCLE PROGRESSION PROTEIN 1 CELL CYCLE PROGRESSION PROTEIN 1 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000003472.5|UniProtKB=F7DBX2 F7DBX2 PSME2 PTHR10660:SF6 PROTEASOME REGULATOR PA28 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 2 enzyme activator activity#GO:0008047;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;peptidase activator activity#GO:0016504;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of protein catabolic process#GO:0042176;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of catabolic process#GO:0009894;regulation of mitotic cell cycle#GO:0007346;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of proteasomal protein catabolic process#GO:0061136 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 Cell cycle#P00013>Proteasome#P00480 MONDO|Ensembl=ENSMODG00000024455.2|UniProtKB=F6Z7Z2 F6Z7Z2 PTHR19339:SF0 T CELL RECEPTOR ALPHA VARIABLE 39 T CELL RECEPTOR ALPHA VARIABLE 41 MONDO|Ensembl=ENSMODG00000013384.4|UniProtKB=F7D8R6 F7D8R6 SCN5A PTHR10037:SF206 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 5 SUBUNIT ALPHA monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated sodium channel activity#GO:0005248;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;passive transmembrane transporter activity#GO:0022803 cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;regulation of multicellular organismal process#GO:0051239;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;transport#GO:0006810;regulation of system process#GO:0044057;system process#GO:0003008;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;sodium ion transport#GO:0006814;action potential#GO:0001508;regulation of biological process#GO:0050789;sensory perception of pain#GO:0019233;regulation of heart contraction#GO:0008016;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;nervous system process#GO:0050877;sensory perception#GO:0007600;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812 plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;axon#GO:0030424;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;transporter complex#GO:1990351 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000014876.4|UniProtKB=F6YKS8 F6YKS8 UBE2E1 PTHR24068:SF70 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 E1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 ISG15-protein conjugation#GO:0032020;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;protein K48-linked ubiquitination#GO:0070936;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000049234.1|UniProtKB=A0A5F8H323 A0A5F8H323 ASF1A PTHR12040:SF8 ANTI-SILENCING PROTEIN 1 HISTONE CHAPERONE ASF1A protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000000671.3|UniProtKB=F6SB70 F6SB70 LOC100010059 PTHR24264:SF15 TRYPSIN-RELATED TRYPSIN serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000020179.4|UniProtKB=A0A5F8GS07 A0A5F8GS07 PTHR15298:SF4 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000017910.4|UniProtKB=F7F2R9 F7F2R9 REV3L PTHR45812:SF1 DNA POLYMERASE ZETA CATALYTIC SUBUNIT DNA POLYMERASE ZETA CATALYTIC SUBUNIT transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;DNA-directed DNA polymerase activity#GO:0003887 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA synthesis involved in DNA replication#GO:0090592;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;translesion synthesis#GO:0019985;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 DNA polymerase complex#GO:0042575;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000005177.4|UniProtKB=F7DNX5 F7DNX5 NOM1 PTHR18034:SF4 CELL CYCLE CONTROL PROTEIN CWF22-RELATED NUCLEOLAR MIF4G DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000003707.2|UniProtKB=A8E6E8 A8E6E8 LOC100021419 PTHR11691:SF37 TYPE I INTERFERON INTERFERON OMEGA-1 molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytokine activity#GO:0005125;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;lymphocyte activation involved in immune response#GO:0002285;signal transduction#GO:0007165;defense response to other organism#GO:0098542;lymphocyte activation#GO:0046649;response to chemical#GO:0042221;response to cytokine#GO:0034097;T cell activation involved in immune response#GO:0002286;humoral immune response#GO:0006959;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;leukocyte activation involved in immune response#GO:0002366;natural killer cell activation#GO:0030101;B cell activation#GO:0042113;T cell activation#GO:0042110;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;B cell activation involved in immune response#GO:0002312;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;response to peptide#GO:1901652;cell activation involved in immune response#GO:0002263;immune response#GO:0006955;multicellular organismal process#GO:0032501;response to other organism#GO:0051707;adaptive immune response#GO:0002250;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cytokine-mediated signaling pathway#GO:0019221;cell activation#GO:0001775;cell communication#GO:0007154;response to nitrogen compound#GO:1901698 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interferon superfamily#PC00127;cytokine#PC00083 MONDO|Ensembl=ENSMODG00000005845.5|UniProtKB=F6TL03 F6TL03 RIPOR1 PTHR15829:SF1 PROTEIN KINASE PKN/PRK1, EFFECTOR RHO FAMILY-INTERACTING CELL POLARIZATION REGULATOR 1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000025709.3|UniProtKB=A0A5F8GCC7 A0A5F8GCC7 PTHR19944:SF59 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ ALPHA 1 CHAIN binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277;protein-containing complex binding#GO:0044877 regulation of lymphocyte activation#GO:0051249;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;immune system process#GO:0002376;regulation of multicellular organismal process#GO:0051239;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of T cell activation#GO:0050863;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of leukocyte activation#GO:0002696;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;positive regulation of cell adhesion#GO:0045785;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of cellular process#GO:0048522;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037 vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;late endosome membrane#GO:0031902;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 MONDO|Ensembl=ENSMODG00000010765.4|UniProtKB=F7FJY5 F7FJY5 PTHR13393:SF0 SAM-DEPENDENT METHYLTRANSFERASE RNA N(6)-ADENOSINE-METHYLTRANSFERASE METTL16 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;post-transcriptional regulation of gene expression#GO:0010608 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155;transferase#PC00220 MONDO|Ensembl=ENSMODG00000012825.3|UniProtKB=F7DD70 F7DD70 LOC100618572 PTHR26453:SF585 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 976 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000022599.2|UniProtKB=F7GD77 F7GD77 TWF1 PTHR13759:SF8 TWINFILIN TWINFILIN-1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin monomer binding#GO:0003785 regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;actin filament depolymerization#GO:0030042;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament length#GO:0030832;cellular component disassembly#GO:0022411;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;protein depolymerization#GO:0051261;negative regulation of protein depolymerization#GO:1901880;regulation of cell projection organization#GO:0031344;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of plasma membrane bounded cell projection organization#GO:0120035;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;protein-containing complex disassembly#GO:0032984;regulation of actin filament depolymerization#GO:0030834;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of protein-containing complex assembly#GO:0031333;supramolecular fiber organization#GO:0097435;regulation of cell projection assembly#GO:0060491 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin filament#GO:0005884;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;contractile muscle fiber#GO:0043292;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000038275.1|UniProtKB=A0A5F8GX60 A0A5F8GX60 PTHR12960:SF0 GLE-1-RELATED MRNA EXPORT FACTOR GLE1 protein binding#GO:0005515;lipid binding#GO:0008289;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;translation initiation factor binding#GO:0031369;alcohol binding#GO:0043178;phospholipid binding#GO:0005543 poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236 nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 translation factor#PC00223 MONDO|Ensembl=ENSMODG00000012844.2|UniProtKB=F7CT37 F7CT37 LOC100023460 PTHR26453:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G7 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024994.1|UniProtKB=F6TU91 F6TU91 ELFN1 PTHR24369:SF237 ANTIGEN BSP, PUTATIVE-RELATED EXTRACELLULAR LEUCINE RICH REPEAT AND FIBRONECTIN TYPE III DOMAIN CONTAINING 1 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000012537.5|UniProtKB=A0A5F8GQY8 A0A5F8GQY8 CORO2A PTHR10856:SF2 CORONIN CORONIN-2A binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000006483.2|UniProtKB=A0A5F8GFF6 A0A5F8GFF6 FABP9 PTHR11955:SF70 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN 9 fatty acid binding#GO:0005504;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;binding#GO:0005488;organic acid binding#GO:0043177 macromolecule localization#GO:0033036;lipid transport#GO:0006869;lipid localization#GO:0010876;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;establishment of localization#GO:0051234;localization#GO:0051179;fatty acid transport#GO:0015908;monocarboxylic acid transport#GO:0015718 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000029075.2|UniProtKB=K7E5I8 K7E5I8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000046157.1|UniProtKB=A0A5F8HDW1 A0A5F8HDW1 PTHR40389:SF3 ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED IGE-BINDING PROTEIN MONDO|Ensembl=ENSMODG00000015807.4|UniProtKB=A0A5F8GCL1 A0A5F8GCL1 MYL1 PTHR23048:SF3 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 1_3, SKELETAL MUSCLE ISOFORM catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;structural molecule activity#GO:0005198;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;organelle#GO:0043226;contractile muscle fiber#GO:0043292;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000014656.2|UniProtKB=F7EQ14 F7EQ14 GAST PTHR19309:SF0 GASTRIN GASTRIN signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;peptide hormone#PC00179 CCKR signaling map#P06959>G34-Gly#P07036;CCKR signaling map#P06959>G34#P07190;CCKR signaling map#P06959>Beta-arrestin-1/2#P07187;CCKR signaling map#P06959>G17 - Gly#P07236;CCKR signaling map#P06959>G17#P07215 MONDO|Ensembl=ENSMODG00000037256.1|UniProtKB=A0A5F8GT85 A0A5F8GT85 PTHR31294:SF8 FAMILY NOT NAMED DUF4657 DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000004391.4|UniProtKB=F6SVS0 F6SVS0 PTHR14392:SF4 NIBAN FAMILY MEMBER PROTEIN NIBAN 3 MONDO|Ensembl=ENSMODG00000048771.1|UniProtKB=A0A5F8G5G6 A0A5F8G5G6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000021396.3|UniProtKB=A0A5F8GVH9 A0A5F8GVH9 SOCS6 PTHR10155:SF32 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 6 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 kinase modulator#PC00140 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879;Interferon-gamma signaling pathway#P00035>SOCS#P00956 MONDO|Ensembl=ENSMODG00000004466.2|UniProtKB=F6VRS1 F6VRS1 LPAR2 PTHR22750:SF38 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 2 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000009347.4|UniProtKB=K7E1Q2 K7E1Q2 HSPH1 PTHR45639:SF2 HSC70CB, ISOFORM G-RELATED HEAT SHOCK PROTEIN 105 KDA molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 Hsp70 family chaperone#PC00027;chaperone#PC00072 MONDO|Ensembl=ENSMODG00000046292.1|UniProtKB=F6YEQ3 F6YEQ3 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000005252.4|UniProtKB=F7GGY0 F7GGY0 SNW1 PTHR12096:SF0 NUCLEAR PROTEIN SKIP-RELATED SNW DOMAIN-CONTAINING PROTEIN 1 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000003474.2|UniProtKB=A0A5F8GAP2 A0A5F8GAP2 PTHR15301:SF10 INSULIN-INDUCED GENE 1 INSULIN-INDUCED GENE 2 PROTEIN cellular response to nitrogen compound#GO:1901699;regulation of signal transduction#GO:0009966;macromolecule localization#GO:0033036;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;intracellular protein localization#GO:0008104;regulation of response to stress#GO:0080134;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;cellular response to peptide hormone stimulus#GO:0071375;cell communication#GO:0007154;localization#GO:0051179;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;response to lipid#GO:0033993;response to chemical#GO:0042221;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;response to hormone#GO:0009725;response to stress#GO:0006950;metabolic process#GO:0008152;cellular response to endogenous stimulus#GO:0071495;small molecule metabolic process#GO:0044281;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;negative regulation of intracellular signal transduction#GO:1902532;regulation of cellular response to stress#GO:0080135;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;negative regulation of response to stimulus#GO:0048585;lipid biosynthetic process#GO:0008610;SREBP signaling pathway#GO:0032933;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;biosynthetic process#GO:0009058;secondary alcohol biosynthetic process#GO:1902653;negative regulation of cellular process#GO:0048523;cholesterol metabolic process#GO:0008203;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;cellular response to lipid#GO:0071396;cholesterol biosynthetic process#GO:0006695;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;alcohol biosynthetic process#GO:0046165;alcohol metabolic process#GO:0006066;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;secondary alcohol metabolic process#GO:1902652;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular localization#GO:0051641;negative regulation of cell communication#GO:0010648;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 MONDO|Ensembl=ENSMODG00000012195.5|UniProtKB=F7CEH3 F7CEH3 TYSND1 PTHR21004:SF0 SERINE PROTEASE-RELATED PEROXISOMAL LEADER PEPTIDE-PROCESSING PROTEASE peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biological regulation#GO:0065007;biosynthetic process#GO:0009058;proteolysis#GO:0006508;regulation of lipid metabolic process#GO:0019216;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of lipid catabolic process#GO:0050994;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794 peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000017051.3|UniProtKB=F6XZE3 F6XZE3 PRPF6 PTHR11246:SF1 PRE-MRNA SPLICING FACTOR PRE-MRNA-PROCESSING FACTOR 6 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000009039.3|UniProtKB=F6TMV7 F6TMV7 PTHR10768:SF23 60S RIBOSOMAL PROTEIN L37 RIBOSOMAL PROTEIN L37 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000040112.1|UniProtKB=A0A5F8G3M2 A0A5F8G3M2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000047963.1|UniProtKB=A0A5F8HCM3 A0A5F8HCM3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000017464.4|UniProtKB=F6Z574 F6Z574 LCK PTHR24418:SF39 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE LCK kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096;non-membrane spanning protein tyrosine kinase activity#GO:0004715;binding#GO:0005488;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515 immune system process#GO:0002376;cell development#GO:0048468;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;mononuclear cell differentiation#GO:1903131;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;T cell differentiation#GO:0030217;lymphocyte activation#GO:0046649;antigen receptor-mediated signaling pathway#GO:0050851;cellular process#GO:0009987;B cell receptor signaling pathway#GO:0050853;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cell activation#GO:0001775;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;lymphocyte differentiation#GO:0030098;regulation of immune response#GO:0050776;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of immune response#GO:0050778;biological regulation#GO:0065007;hemopoiesis#GO:0030097;immune response-regulating cell surface receptor signaling pathway#GO:0002768;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 T cell activation#P00053>Lck#P01310;Parkinson disease#P00049>Src kinase#P01230 MONDO|Ensembl=ENSMODG00000005217.4|UniProtKB=F7A1T5 F7A1T5 NDST4 PTHR10605:SF45 HEPARAN SULFATE SULFOTRANSFERASE N-HEPARAN SULFATE SULFOTRANSFERASE 4 deacylase activity#GO:0160215;transferase activity#GO:0016740;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000017384.4|UniProtKB=A0A5F8H1D0 A0A5F8H1D0 CHTOP PTHR19965:SF22 RNA AND EXPORT FACTOR BINDING PROTEIN CHROMATIN TARGET OF PRMT1-LIKE 1 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;localization#GO:0051179;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000002154.4|UniProtKB=F6YEX7 F6YEX7 SARS1 PTHR11778:SF7 SERYL-TRNA SYNTHETASE SERINE--TRNA LIGASE, CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000028855.2|UniProtKB=F6RA87 F6RA87 LOC107651401 PTHR23226:SF10 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 21 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000044571.1|UniProtKB=A0A5F8G8Y5 A0A5F8G8Y5 PTHR19303:SF27 TRANSPOSON HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009618.5|UniProtKB=A0A5F8GQ07 A0A5F8GQ07 CACNB2 PTHR11824:SF9 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2 cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;regulation of biological process#GO:0050789;cellular process#GO:0009987 voltage-gated ion channel#PC00241 Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438 MONDO|Ensembl=ENSMODG00000008161.4|UniProtKB=F6W3N1 F6W3N1 VN2R533 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000048967.1|UniProtKB=A0A5F8H6I8 A0A5F8H6I8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000040530.1|UniProtKB=A0A5F8H4A1 A0A5F8H4A1 ZBTB2 PTHR24399:SF0 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 2 sequence-specific DNA binding#GO:0043565;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000007529.4|UniProtKB=F7GJL8 F7GJL8 ATG14 PTHR13664:SF0 BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;kinase regulator activity#GO:0019207;protein-membrane adaptor activity#GO:0043495;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular response to nutrient levels#GO:0031669;autophagosome maturation#GO:0097352;autophagy of mitochondrion#GO:0000422;cellular response to starvation#GO:0009267;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;cellular response to stress#GO:0033554;organelle localization#GO:0051640;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;localization#GO:0051179;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;response to stimulus#GO:0050896 phagophore assembly site#GO:0000407;transferase complex#GO:1990234;extrinsic component of membrane#GO:0019898;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;autophagosome#GO:0005776;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex, class III#GO:0035032;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000015950.4|UniProtKB=F7FRV0 F7FRV0 RAB26 PTHR47978:SF65 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-26 hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of secretion#GO:0051046 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000006392.3|UniProtKB=F7G224 F7G224 PTHR46469:SF1 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 General transcription by RNA polymerase I#P00022>TAF-IB#P00650;General transcription by RNA polymerase I#P00022>TAF-IA#P00651;General transcription by RNA polymerase I#P00022>TAF-IC#P00649;General transcription regulation#P00023>TBP-associated factors#P00658;General transcription by RNA polymerase I#P00022>SL1 complex#P00653;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 MONDO|Ensembl=ENSMODG00000012204.3|UniProtKB=F7CE72 F7CE72 PTHR16983:SF28 UPAR/LY6 DOMAIN-CONTAINING PROTEIN LYMPHOCYTE ANTIGEN 6 FAMILY MEMBER M signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;acetylcholine receptor inhibitor activity#GO:0030550;binding#GO:0005488;acetylcholine receptor regulator activity#GO:0030548;signaling receptor inhibitor activity#GO:0030547;neurotransmitter receptor regulator activity#GO:0099602;molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515 response to nitrogen compound#GO:1901698;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;synaptic signaling#GO:0099536 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000028344.2|UniProtKB=K7E584 K7E584 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013273.5|UniProtKB=F7AAC0 F7AAC0 ETV5 PTHR11849:SF160 ETS ETS TRANSLOCATION VARIANT 5 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000001784.4|UniProtKB=F6SAP8 F6SAP8 CELF6 PTHR24012:SF716 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 6 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of RNA splicing#GO:0043484;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000051538.1|UniProtKB=A0A5F8H840 A0A5F8H840 TNFRSF6B PTHR23097:SF116 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6B transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010002.4|UniProtKB=F6URV1 F6URV1 PTHR24376:SF258 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 814 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000029679.2|UniProtKB=K7DYZ7 K7DYZ7 LOC103098191 PTHR16675:SF289 MHC CLASS I-RELATED ZINC-ALPHA-2-GLYCOPROTEIN positive regulation of response to stimulus#GO:0048584;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000018014.5|UniProtKB=A0ACM8QE23 A0ACM8QE23 SOBP PTHR23186:SF2 RETINOIC ACID-INDUCED PROTEIN 2 SINE OCULIS-BINDING PROTEIN HOMOLOG sensory organ development#GO:0007423;developmental process#GO:0032502;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;inner ear morphogenesis#GO:0042472;inner ear development#GO:0048839;multicellular organismal process#GO:0032501;embryo development#GO:0009790;animal gross anatomical part developmental process#GO:0160108;embryonic organ development#GO:0048568;anatomical structure development#GO:0048856;ear development#GO:0043583;anatomical structure morphogenesis#GO:0009653;animal organ morphogenesis#GO:0009887;sensory organ morphogenesis#GO:0090596 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000005839.3|UniProtKB=F6U1F7 F6U1F7 LOC100026609 PTHR10151:SF65 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE 7 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000024558.2|UniProtKB=F7F1K4 F7F1K4 OR10S1 PTHR26453:SF205 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10S1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000116.4|UniProtKB=A0A5F8G3Y0 A0A5F8G3Y0 MTMR2 PTHR10807:SF42 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR2 phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;dephosphorylation#GO:0016311;lipid modification#GO:0030258 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000049670.1|UniProtKB=A0A5F8GVX5 A0A5F8GVX5 ACYP2 PTHR10029:SF20 ACYLPHOSPHATASE ACYLPHOSPHATASE-2 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000046968.1|UniProtKB=A0A5F8G3R1 A0A5F8G3R1 ADORA3 PTHR24246:SF2 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A3 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell surface receptor signaling pathway#GO:0007166;G protein-coupled adenosine receptor signaling pathway#GO:0001973;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 MONDO|Ensembl=ENSMODG00000037562.1|UniProtKB=A0A5F8H2G7 A0A5F8H2G7 WNT5B PTHR12027:SF87 WNT RELATED PROTEIN WNT-5B signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125 cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;system development#GO:0048731;cell fate commitment#GO:0045165 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 MONDO|Ensembl=ENSMODG00000003781.4|UniProtKB=A0A5F8GH24 A0A5F8GH24 MTAP PTHR42679:SF2 S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 Purine metabolism#P02769>Nucleoside Phosphorylase#P03115 MONDO|Ensembl=ENSMODG00000047267.1|UniProtKB=A0A5F8GL70 A0A5F8GL70 PTHR11346:SF97 GALECTIN GALECTIN-1 extracellular matrix binding#GO:0050840;carbohydrate binding#GO:0030246;protein binding#GO:0005515;binding#GO:0005488;oligosaccharide binding#GO:0070492;laminin binding#GO:0043236 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000021268.4|UniProtKB=F6T2X0 F6T2X0 RNF13 PTHR22765:SF34 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF13 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;cellular process#GO:0009987;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000046943.1|UniProtKB=A0A5F8H1I2 A0A5F8H1I2 PTHR40389:SF3 ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED IGE-BINDING PROTEIN MONDO|Ensembl=ENSMODG00000041827.1|UniProtKB=A0A5F8H7T3 A0A5F8H7T3 PTHR23262:SF7 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 2-2-RELATED structural protein#PC00211 MONDO|Ensembl=ENSMODG00000020182.4|UniProtKB=F7GHV3 F7GHV3 DTX4 PTHR12622:SF5 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX4 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000020774.4|UniProtKB=A0A5F8GYA1 A0A5F8GYA1 HELQ PTHR47961:SF12 DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED HELICASE POLQ-LIKE macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 DNA double-strand break processing#GO:0000729;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;double-strand break repair via single-strand annealing#GO:0045002 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000006845.4|UniProtKB=A0A5F8GC80 A0A5F8GC80 NADK PTHR20275:SF44 NAD KINASE NAD KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 nucleotide kinase#PC00172 MONDO|Ensembl=ENSMODG00000015860.4|UniProtKB=F7F0A8 F7F0A8 DDR1 PTHR24416:SF333 TYROSINE-PROTEIN KINASE RECEPTOR EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein-containing complex binding#GO:0044877;collagen binding#GO:0005518;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of intracellular signal transduction#GO:1902531;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006785.4|UniProtKB=F6PH65 F6PH65 WDR83 PTHR22842:SF3 WD40 REPEAT PROTEIN WD REPEAT DOMAIN-CONTAINING PROTEIN 83 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000004292.4|UniProtKB=F6SXZ4 F6SXZ4 TRAPPC11 PTHR14374:SF0 FOIE GRAS TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 11 MONDO|Ensembl=ENSMODG00000000868.4|UniProtKB=A0A5F8G7J9 A0A5F8G7J9 PTHR24347:SF376 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE DCLK2 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000027493.2|UniProtKB=K7E365 K7E365 PTHR10206:SF2 CATHELICIDIN CATHELICIDIN ANTIMICROBIAL PEPTIDE lipopolysaccharide binding#GO:0001530;carbohydrate derivative binding#GO:0097367;binding#GO:0005488;lipid binding#GO:0008289 defense response to Gram-positive bacterium#GO:0050830;defense response to Gram-negative bacterium#GO:0050829;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051 MONDO|Ensembl=ENSMODG00000004526.4|UniProtKB=F6UQC2 F6UQC2 PRIMPOL PTHR31399:SF0 DNA-DIRECTED PRIMASE / POLYMERASE PROTEIN DNA-DIRECTED PRIMASE_POLYMERASE PROTEIN DNA-directed DNA polymerase activity#GO:0003887;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity, acting on RNA#GO:0140098;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to abiotic stimulus#GO:0009628;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA-templated DNA replication#GO:0006261;mitochondrial DNA metabolic process#GO:0032042;DNA synthesis involved in DNA replication#GO:0090592;response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;response to radiation#GO:0009314;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translesion synthesis#GO:0019985;replication fork processing#GO:0031297;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;response to UV#GO:0009411;DNA damage tolerance#GO:0006301;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;mitochondrion#GO:0005739 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000012073.3|UniProtKB=A0A5F8HD08 A0A5F8HD08 LRRC8D PTHR45752:SF11 LEUCINE-RICH REPEAT-CONTAINING VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8D channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 import across plasma membrane#GO:0098739;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;signal transduction#GO:0007165;import into cell#GO:0098657;amino acid transport#GO:0006865;organic acid transport#GO:0015849;acidic amino acid transport#GO:0015800;carboxylic acid transport#GO:0046942;regulation of cellular process#GO:0050794;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;carboxylic acid transmembrane transport#GO:1905039;monoatomic anion transport#GO:0006820;carbohydrate derivative transport#GO:1901264;cellular response to stimulus#GO:0051716;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;monoatomic ion transmembrane transport#GO:0034220;dicarboxylic acid transport#GO:0006835;biological regulation#GO:0065007;nitrogen compound transport#GO:0071705;aspartate transmembrane transport#GO:0015810;establishment of localization#GO:0051234;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810 intracellular anatomical structure#GO:0005622;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000038704.1|UniProtKB=A0A5F8GKR1 A0A5F8GKR1 PTHR11434:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT ND4L NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4L respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000002762.3|UniProtKB=F6YH41 F6YH41 ASIP PTHR16551:SF1 AGOUTI RELATED AGOUTI-SIGNALING PROTEIN hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;neuropeptide hormone activity#GO:0005184;G protein-coupled receptor binding#GO:0001664;neuropeptide receptor binding#GO:0071855;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000009461.4|UniProtKB=F7B7D3 F7B7D3 BDNF PTHR11589:SF3 NERVE GROWTH FACTOR NGF -RELATED NEUROTROPHIC FACTOR BDNF PRECURSOR FORM receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;negative regulation of apoptotic process#GO:0043066;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cell projection organization#GO:0030030;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular response to growth factor stimulus#GO:0071363;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;regulation of trans-synaptic signaling#GO:0099177;nervous system development#GO:0007399;regulation of neuron apoptotic process#GO:0043523;neuron projection development#GO:0031175;negative regulation of neuron apoptotic process#GO:0043524;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular response to nerve growth factor stimulus#GO:1990090;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039 cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;presynapse#GO:0098793;secretory vesicle#GO:0099503;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;extracellular region#GO:0005576;exocytic vesicle#GO:0070382 growth factor#PC00112;neurotrophic factor#PC00163 Metabotropic glutamate receptor group II pathway#P00040>BDNF#G01540;Huntington disease#P00029>BDNF#G01531;Huntington disease#P00029>BDNF#P00795 MONDO|Ensembl=ENSMODG00000006084.4|UniProtKB=A0A5F8HAX0 A0A5F8HAX0 PLEKHG5 PTHR13217:SF11 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 5 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cellular process#GO:0009987;endothelial cell migration#GO:0043542;cell motility#GO:0048870;cell migration#GO:0016477 cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000001950.3|UniProtKB=F6VJQ0 F6VJQ0 BCL2L10 PTHR11256:SF47 BCL-2 RELATED BCL-2-LIKE PROTEIN 10 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;release of cytochrome c from mitochondria#GO:0001836;positive regulation of programmed cell death#GO:0043068;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway#GO:0097193;positive regulation of cellular process#GO:0048522;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;apoptotic signaling pathway#GO:0097190;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 Apoptosis signaling pathway#P00006>Diva#P00285 MONDO|Ensembl=ENSMODG00000008489.4|UniProtKB=F7DV81 F7DV81 LSS PTHR11764:SF94 TERPENE CYCLASE/MUTASE FAMILY MEMBER LANOSTEROL SYNTHASE isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;secondary alcohol biosynthetic process#GO:1902653;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125 lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 lyase#PC00144;cyclase#PC00079 Cholesterol biosynthesis#P00014>Anosterol synthase#P00497 MONDO|Ensembl=ENSMODG00000009567.3|UniProtKB=F7BJ34 F7BJ34 PTHR45255:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 24 DNAJ HOMOLOG SUBFAMILY C MEMBER 24 molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671;iron ion binding#GO:0005506;ferrous iron binding#GO:0008198;cation binding#GO:0043169;molecular function activator activity#GO:0140677;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000006241.4|UniProtKB=A0A5F8GFF9 A0A5F8GFF9 RPS6KA2 PTHR24351:SF213 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;TOR signaling#GO:0031929;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;TORC1 signaling#GO:0038202 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142;Interleukin signaling pathway#P00036>p90RSK#P00964;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;Ras Pathway#P04393>p90RSK#P04541 MONDO|Ensembl=ENSMODG00000015382.4|UniProtKB=A0A5F8G8Q8 A0A5F8G8Q8 VIT PTHR24020:SF23 COLLAGEN ALPHA VITRIN regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cell-substrate adhesion#GO:0010811;cellular process#GO:0009987;positive regulation of cell adhesion#GO:0045785;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;extracellular structure organization#GO:0043062 interstitial matrix#GO:0005614;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000046723.1|UniProtKB=F7G0L1 F7G0L1 LOC103101350 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019515.4|UniProtKB=F6VD74 F6VD74 PTHR23036:SF96 CYTOKINE RECEPTOR INTERLEUKIN-31 RECEPTOR SUBUNIT ALPHA molecular transducer activity#GO:0060089;protein binding#GO:0005515;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896 cell surface receptor signaling pathway#GO:0007166;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008324.5|UniProtKB=A0A5F8GTW4 A0A5F8GTW4 DIP2A PTHR22754:SF34 DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED DISCO-INTERACTING PROTEIN 2 HOMOLOG A ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 positive regulation of metabolic process#GO:0009893;organophosphate biosynthetic process#GO:0090407;positive regulation of protein metabolic process#GO:0051247;acetyl-CoA metabolic process#GO:0006084;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;regulation of protein modification process#GO:0031399;nucleoside phosphate biosynthetic process#GO:1901293;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;organophosphate metabolic process#GO:0019637;regulation of protein metabolic process#GO:0051246;sulfur compound metabolic process#GO:0006790;regulation of metabolic process#GO:0019222 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000004160.2|UniProtKB=F6R9W7 F6R9W7 RNF166 PTHR46016:SF4 ZINC FINGER, RING/FYVE/PHD-TYPE E3 UBIQUITIN-PROTEIN LIGASE RNF166 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 MONDO|Ensembl=ENSMODG00000005028.4|UniProtKB=F7ER08 F7ER08 SHH PTHR11889:SF36 HEDGEHOG SONIC HEDGEHOG PROTEIN cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;signaling receptor binding#GO:0005102;binding#GO:0005488 signaling#GO:0023052;central nervous system development#GO:0007417;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;gliogenesis#GO:0042063;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;cell fate specification#GO:0001708;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;smoothened signaling pathway#GO:0007224;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;biological regulation#GO:0065007;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;oligodendrocyte differentiation#GO:0048709;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Hedgehog signaling pathway#P00025>Hedgehog#P00688 MONDO|Ensembl=ENSMODG00000014292.3|UniProtKB=F6WKA5 F6WKA5 SNTG2 PTHR10554:SF3 SYNTROPHIN GAMMA-2-SYNTROPHIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017417.3|UniProtKB=F7AJC4 F7AJC4 TNFAIP3 PTHR13367:SF3 UBIQUITIN THIOESTERASE TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 3 acyltransferase activity#GO:0016746;deubiquitinase activity#GO:0101005;ubiquitin-like protein transferase activity#GO:0019787;hydrolase activity#GO:0016787;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;transferase activity#GO:0016740;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;aminoacyltransferase activity#GO:0016755;ubiquitin-like protein peptidase activity#GO:0019783 regulation of response to external stimulus#GO:0032101;positive regulation of Wnt signaling pathway#GO:0030177;negative regulation of innate immune response#GO:0045824;negative regulation of signal transduction#GO:0009968;negative regulation of response to external stimulus#GO:0032102;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of Wnt signaling pathway#GO:0030111;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;protein modification by small protein conjugation or removal#GO:0070647;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;post-translational protein modification#GO:0043687;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of innate immune response#GO:0045088;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;negative regulation of defense response#GO:0031348;regulation of cellular process#GO:0050794;negative regulation of inflammatory response#GO:0050728;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;catabolic process#GO:0009056;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;protein modification process#GO:0036211;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;negative regulation of immune response#GO:0050777;regulation of immune response#GO:0050776 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease#PC00190;cysteine protease#PC00081 Toll receptor signaling pathway#P00054>A20#P01348 MONDO|Ensembl=ENSMODG00000028064.2|UniProtKB=K7E087 K7E087 PTHR12015:SF111 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 17 cytokine#PC00083 MONDO|Ensembl=ENSMODG00000046977.1|UniProtKB=A0A5F8H172 A0A5F8H172 PTHR48018:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015429.5|UniProtKB=A0A5F8HJI5 A0A5F8HJI5 FAM98A PTHR31353:SF9 FAM98 PROTEIN FAM98A protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000004557.3|UniProtKB=A0A5F8GDG0 A0A5F8GDG0 PTHR35540:SF1 IZUMO SPERM-EGG FUSION PROTEIN 1 IZUMO SPERM-EGG FUSION PROTEIN 1 binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cell-cell adhesion mediator activity#GO:0098632 multicellular organismal reproductive process#GO:0048609;cell-cell recognition#GO:0009988;binding of sperm to zona pellucida#GO:0007339;cell recognition#GO:0008037;sexual reproduction#GO:0019953;sperm-egg recognition#GO:0035036;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;fertilization#GO:0009566;cellular process#GO:0009987;fusion of sperm to egg plasma membrane involved in single fertilization#GO:0007342;single fertilization#GO:0007338 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;acrosomal membrane#GO:0002080;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000002461.2|UniProtKB=F7DEE3 F7DEE3 FAM131A PTHR15736:SF4 PROTEIN FAM131B-RELATED PROTEIN FAM131A MONDO|Ensembl=ENSMODG00000015822.4|UniProtKB=F7FDY1 F7FDY1 MET PTHR24416:SF483 TYROSINE-PROTEIN KINASE RECEPTOR HEPATOCYTE GROWTH FACTOR RECEPTOR protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;endocytosis#GO:0006897;liver development#GO:0001889;signaling#GO:0023052;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;import into cell#GO:0098657;animal organ development#GO:0048513;signal transduction#GO:0007165;cellular process#GO:0009987;nervous system development#GO:0007399;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;localization#GO:0051179;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;cellular response to stimulus#GO:0051716;pancreas development#GO:0031016;cell motility#GO:0048870;regulation of cellular process#GO:0050794;phagocytosis#GO:0006909;developmental process#GO:0032502;transport#GO:0006810;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;neurogenesis#GO:0022008;cell migration#GO:0016477;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 signaling receptor complex#GO:0043235;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000039402.1|UniProtKB=A0A5F8GDT1 A0A5F8GDT1 PTHR35154:SF3 GBP PROTEIN GBP PROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000019697.4|UniProtKB=F6TCJ0 F6TCJ0 PTHR45755:SF1 FAMILY NOT NAMED PROTON-COUPLED ZINC ANTIPORTER SLC30A5 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;zinc ion transmembrane transport#GO:0071577;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;Golgi cis cisterna#GO:0000137;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;vesicle#GO:0031982;Golgi stack#GO:0005795;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 MONDO|Ensembl=ENSMODG00000047156.1|UniProtKB=A0A5F8G5U6 A0A5F8G5U6 MYH3 PTHR45615:SF6 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-3 actin filament binding#GO:0051015;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 system process#GO:0003008;multicellular organismal process#GO:0032501;muscle contraction#GO:0006936;muscle system process#GO:0003012 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522 MONDO|Ensembl=ENSMODG00000008471.4|UniProtKB=A0A5F8GNH8 A0A5F8GNH8 STX8 PTHR19957:SF285 SYNTAXIN SYNTAXIN-8 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;membrane fusion#GO:0061025;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031 cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 MONDO|Ensembl=ENSMODG00000019516.4|UniProtKB=F6VD67 F6VD67 IDH2 PTHR11822:SF46 NADP-SPECIFIC ISOCITRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;NADP+ metabolic process#GO:0006739;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nicotinamide nucleotide metabolic process#GO:0046496;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;pyridine-containing compound metabolic process#GO:0072524 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000011514.4|UniProtKB=F6UIS9 F6UIS9 PTHR21694:SF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 MONDO|Ensembl=ENSMODG00000015450.3|UniProtKB=F6S411 F6S411 ADRA1D PTHR24248:SF14 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-1D ADRENERGIC RECEPTOR G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;regulation of system process#GO:0044057;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of anatomical structure size#GO:0090066;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;system process#GO:0003008;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;regulation of biological quality#GO:0065008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 MONDO|Ensembl=ENSMODG00000012758.4|UniProtKB=F6SJI7 F6SJI7 GUCA1A PTHR23055:SF13 CALCIUM BINDING PROTEINS GUANYLYL CYCLASE-ACTIVATING PROTEIN 1 metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;cyclase regulator activity#GO:0010851 visual perception#GO:0007601;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of light stimulus#GO:0050953;sensory perception#GO:0007600;nervous system process#GO:0050877 photoreceptor inner segment#GO:0001917;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;9+0 non-motile cilium#GO:0097731;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000014904.4|UniProtKB=F7G6F7 F7G6F7 FAM32A PTHR13282:SF6 PROTEIN FAM32A PROTEIN FAM32A membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681 MONDO|Ensembl=ENSMODG00000041560.1|UniProtKB=A0A5F8GP97 A0A5F8GP97 CACNG4 PTHR12107:SF7 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-4 SUBUNIT calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832 system process#GO:0003008;transmission of nerve impulse#GO:0019226;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of biological quality#GO:0065008;regulation of synaptic transmission, glutamatergic#GO:0051966;localization#GO:0051179;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;cellular localization#GO:0051641;localization within membrane#GO:0051668;nervous system process#GO:0050877;regulation of signaling#GO:0023051;positive regulation of synaptic transmission#GO:0050806;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;transporter complex#GO:1990351;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235 voltage-gated ion channel#PC00241;transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000005740.4|UniProtKB=F6QE91 F6QE91 TTLL5 PTHR12241:SF164 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL5 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;tubulin binding#GO:0015631;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;sperm motility#GO:0097722;cell projection organization#GO:0030030;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414 microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000011812.4|UniProtKB=A0A5F8G3W2 A0A5F8G3W2 RPAP2 PTHR14732:SF0 RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;snRNA transcription#GO:0009301 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000046178.1|UniProtKB=A0A5F8G6U5 A0A5F8G6U5 BLOC1S5 PTHR31784:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 5 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 5 cellular response to stimulus#GO:0051716;microtubule-based movement#GO:0007018;pigmentation#GO:0043473;axonal transport#GO:0098930;organelle localization#GO:0051640;anterograde axonal transport#GO:0008089;localization#GO:0051179;vesicle localization#GO:0051648;axo-dendritic transport#GO:0008088;developmental maturation#GO:0021700;cytoskeleton-dependent intracellular transport#GO:0030705;developmental process#GO:0032502;transport#GO:0006810;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;vesicle cytoskeletal trafficking#GO:0099518;response to external stimulus#GO:0009605;anterograde synaptic vesicle transport#GO:0048490;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;response to stimulus#GO:0050896;cell differentiation#GO:0030154;establishment of organelle localization#GO:0051656;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;developmental pigmentation#GO:0048066;synaptic vesicle transport#GO:0048489;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;cellular pigmentation#GO:0033059;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;microtubule-based process#GO:0007017 intracellular protein-containing complex#GO:0140535;BLOC-1 complex#GO:0031083;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000003737.4|UniProtKB=F7ED92 F7ED92 TFDP1 PTHR12548:SF4 TRANSCRIPTION FACTOR DP TRANSCRIPTION FACTOR DP-1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000046600.1|UniProtKB=A0A5F8GKB8 A0A5F8GKB8 monDomV1R1269 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008253.3|UniProtKB=F6ZX76 F6ZX76 RAB18 PTHR24073:SF1242 DRAB5-RELATED RAS-RELATED PROTEIN RAB-18 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;lipid droplet organization#GO:0034389 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000023329.2|UniProtKB=F6V8P7 F6V8P7 PLN PTHR21194:SF1 CARDIAC PHOSPHOLAMBAN PHOSPHOLAMBAN molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;negative regulation of transport#GO:0051051;regulation of heart contraction#GO:0008016;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523;regulation of system process#GO:0044057;regulation of monoatomic ion transport#GO:0043269;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;sarcoplasmic reticulum#GO:0016529;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;sarcoplasm#GO:0016528 MONDO|Ensembl=ENSMODG00000029694.2|UniProtKB=A0A5F8H9E4 A0A5F8H9E4 ERICH2 PTHR21520:SF2 GLUTAMATE-RICH PROTEIN 2 GLUTAMATE-RICH PROTEIN 2 MONDO|Ensembl=ENSMODG00000002705.4|UniProtKB=F7CXW9 F7CXW9 DMAP1 PTHR12855:SF10 DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 FAMILY MEMBER DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 acetyltransferase complex#GO:1902493;ATPase complex#GO:1904949;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;chromatin#GO:0000785;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;intracellular membrane-bounded organelle#GO:0043231;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;nuclear chromosome#GO:0000228;H4 histone acetyltransferase complex#GO:1902562;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000009035.2|UniProtKB=F7B2I0 F7B2I0 PTHR11947:SF14 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 1, MITOCHONDRIAL phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of biosynthetic process#GO:0009889;regulation of carbohydrate metabolic process#GO:0006109;regulation of lipid metabolic process#GO:0019216;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000007533.3|UniProtKB=F7GB79 F7GB79 GPR26 PTHR24245:SF6 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 26 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cell communication#GO:0007154 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002293.4|UniProtKB=F7CBZ9 F7CBZ9 IL1R2 PTHR11890:SF3 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR TYPE 2 transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037414.1|UniProtKB=F6RDD7 F6RDD7 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000038338.1|UniProtKB=A0A5F8G9E5 A0A5F8G9E5 PTHR37866:SF2 PRE T-CELL ANTIGEN RECEPTOR ALPHA PROTEIN CANOPY HOMOLOG 3 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000001995.3|UniProtKB=F6RHW2 F6RHW2 C7H9orf40 PTHR16003:SF3 C9ORF40 ISOFORM 1 CHROMOSOME 1 C9ORF40 HOMOLOG MONDO|Ensembl=ENSMODG00000039761.1|UniProtKB=A0A5F8G6B9 A0A5F8G6B9 PTHR31792:SF3 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000019675.4|UniProtKB=F6TTU8 F6TTU8 CD180 PTHR24373:SF356 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN CD180 ANTIGEN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018184.5|UniProtKB=F7BTK7 F7BTK7 GAP43 PTHR10699:SF15 NEUROMODULIN NEUROMODULIN binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;protein binding#GO:0005515;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;phospholipid binding#GO:0005543;calmodulin binding#GO:0005516;carbohydrate derivative binding#GO:0097367;phosphatidylinositol phosphate binding#GO:1901981 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;tissue regeneration#GO:0042246;neuron development#GO:0048666;axonogenesis#GO:0007409;neuron projection development#GO:0031175;cellular process#GO:0009987;nervous system development#GO:0007399;regeneration#GO:0031099;cell morphogenesis involved in neuron differentiation#GO:0048667;growth#GO:0040007;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;cell recognition#GO:0008037;anatomical structure development#GO:0048856;system development#GO:0048731;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;developmental growth#GO:0048589;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485 postsynaptic density#GO:0014069;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944;organelle#GO:0043226;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;plasma membrane#GO:0005886;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000012958.4|UniProtKB=A0A5F8HEW5 A0A5F8HEW5 HSPA8 PTHR19375:SF564 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787 localization#GO:0051179;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;protein refolding#GO:0042026;endocytosis#GO:0006897;protein-containing complex disassembly#GO:0032984;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;clathrin-dependent endocytosis#GO:0072583;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;transport#GO:0006810;protein maturation#GO:0051604;gene expression#GO:0010467;vesicle-mediated transport#GO:0016192;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 Hsp70 family chaperone#PC00027;chaperone#PC00072 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 MONDO|Ensembl=ENSMODG00000018801.4|UniProtKB=F6ZMX1 F6ZMX1 MCL1 PTHR11256:SF46 BCL-2 RELATED INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN MCL-1 channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;organelle fusion#GO:0048284;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;response to stress#GO:0006950;regulation of neuron apoptotic process#GO:0043523;organelle organization#GO:0006996;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;signaling#GO:0023052;release of cytochrome c from mitochondria#GO:0001836;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;positive regulation of neuron apoptotic process#GO:0043525;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;mitochondrial fusion#GO:0008053 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967 CCKR signaling map#P06959>MCL1#G07275;CCKR signaling map#P06959>MCL1#G06982;Apoptosis signaling pathway#P00006>Mcl1#P00308 MONDO|Ensembl=ENSMODG00000021303.3|UniProtKB=F7G3J2 F7G3J2 GNB4 PTHR19850:SF28 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-4 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;signaling adaptor activity#GO:0035591 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897 protein-binding activity modulator#PC00095;G-protein#PC00020;heterotrimeric G-protein#PC00117 Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753;Enkephalin release#P05913>G-Protein (i)#P05974;Enkephalin release#P05913>G-Protein (s)#P05977;GABA-B receptor II signaling#P05731>Gbeta#P05755;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Wnt signaling pathway#P00057>GBeta#P01457;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;PI3 kinase pathway#P00048>Gbetagamma#P01188;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Endogenous cannabinoid signaling#P05730>Gbeta#P05745 MONDO|Ensembl=ENSMODG00000042372.1|UniProtKB=A0A5F8GVE5 A0A5F8GVE5 PRRG1 PTHR24278:SF37 COAGULATION FACTOR TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 1 catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000004489.4|UniProtKB=A0A5F8GXI0 A0A5F8GXI0 CSMD3 PTHR45656:SF9 PROTEIN CBR-CLEC-78 CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 3 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000015575.4|UniProtKB=F7AIN7 F7AIN7 FOSL2 PTHR23351:SF25 FOS TRANSCRIPTION FACTOR-RELATED FOS-RELATED ANTIGEN 2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 MONDO|Ensembl=ENSMODG00000041352.1|UniProtKB=K7DZ65 K7DZ65 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000005511.4|UniProtKB=A0A5F8HGW9 A0A5F8HGW9 TMEM63C PTHR13018:SF21 PROBABLE MEMBRANE PROTEIN DUF221-RELATED OSMOSENSITIVE CATION CHANNEL TMEM63C channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion-gated channel activity#GO:0022839;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000001647.3|UniProtKB=F6T7N4 F6T7N4 EMC7 PTHR13605:SF4 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7 ENDOPLASMIC RETICULUM MEMBRANE PROTEIN COMPLEX SUBUNIT 7 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000007218.2|UniProtKB=F6WSL8 F6WSL8 MALL PTHR22776:SF24 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MAL-LIKE PROTEIN regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;membrane microdomain#GO:0098857;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;membrane raft#GO:0045121 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000050817.1|UniProtKB=A0A5F8GQI2 A0A5F8GQI2 PTHR11267:SF125 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX21 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cell migration#GO:0016477;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;lymphocyte migration#GO:0072676;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;leukocyte migration#GO:0050900;cell fate specification#GO:0001708;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;mononuclear cell migration#GO:0071674;immune system process#GO:0002376 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 MONDO|Ensembl=ENSMODG00000002781.4|UniProtKB=F7AP44 F7AP44 FANCC PTHR16798:SF0 FANCONI ANEMIA GROUP C PROTEIN FANCC FANCONI ANEMIA GROUP C PROTEIN cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular process#GO:0009987;response to stress#GO:0006950;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Fanconi anaemia nuclear complex#GO:0043240;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000017053.4|UniProtKB=F6XZC6 F6XZC6 PKLR PTHR11817:SF31 PYRUVATE KINASE PYRUVATE KINASE PKLR phosphotransferase activity, alcohol group as acceptor#GO:0016773;pyruvate kinase activity#GO:0004743;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate catabolic process#GO:1901292;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;response to peptide hormone#GO:0043434;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;cellular response to insulin stimulus#GO:0032869;ADP metabolic process#GO:0046031;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;cellular response to chemical stimulus#GO:0070887;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ADP catabolic process#GO:0046032;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;cellular response to peptide hormone stimulus#GO:0071375;catabolic process#GO:0009056;purine nucleotide catabolic process#GO:0006195;response to nitrogen compound#GO:1901698;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;cellular response to nitrogen compound#GO:1901699;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ribonucleoside diphosphate metabolic process#GO:0009185;response to endogenous stimulus#GO:0009719;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;response to hormone#GO:0009725;response to chemical#GO:0042221;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;purine-containing compound catabolic process#GO:0072523 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 kinase#PC00137 Pyruvate metabolism#P02772>Pyruvate Kinase#P03132;Glycolysis#P00024>Pyruvate kinase#P00675 MONDO|Ensembl=ENSMODG00000010037.2|UniProtKB=F6TUF2 F6TUF2 PIM2 PTHR22984:SF10 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE PIM-2 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;positive regulation of signal transduction#GO:0009967;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of mitotic cell cycle#GO:0007346;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;positive regulation of canonical NF-kappaB signal transduction#GO:0043123 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000046586.1|UniProtKB=A0A5F8GQS1 A0A5F8GQS1 PTHR23209:SF4 A-KINASE ANCHOR PROTEIN 12 A-KINASE ANCHOR PROTEIN 12 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019510.3|UniProtKB=F6VDC0 F6VDC0 CIB1 PTHR45791:SF3 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN-BINDING PROTEIN 1 metal ion binding#GO:0046872;cation binding#GO:0043169;magnesium ion binding#GO:0000287;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 MONDO|Ensembl=ENSMODG00000020626.4|UniProtKB=F6ZAN7 F6ZAN7 GSTCD PTHR13369:SF4 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN inflammatory response#GO:0006954;response to stress#GO:0006950;defense response#GO:0006952;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000009542.4|UniProtKB=F7C424 F7C424 TLE4 PTHR10814:SF31 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 4 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 MONDO|Ensembl=ENSMODG00000048696.1|UniProtKB=A0A5F8GZM2 A0A5F8GZM2 LOC100031204 PTHR24249:SF78 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 7A-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000020908.4|UniProtKB=H9H7S0 H9H7S0 SPATA20 PTHR42899:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 20 SPERMATOGENESIS-ASSOCIATED PROTEIN 20 MONDO|Ensembl=ENSMODG00000048981.1|UniProtKB=A0A5F8GHX7 A0A5F8GHX7 PRDM8 PTHR16516:SF7 AGAP007109-PA PR DOMAIN ZINC FINGER PROTEIN 8 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000039471.1|UniProtKB=A0A5F8G2A4 A0A5F8G2A4 PTHR26453:SF255 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000043169.1|UniProtKB=A0A5F8H0G7 A0A5F8H0G7 PTHR11596:SF74 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 developmental process#GO:0032502;biomineral tissue development#GO:0031214;animal gross anatomical part developmental process#GO:0160108;bone mineralization#GO:0030282;anatomical structure development#GO:0048856;animal organ development#GO:0048513;ossification#GO:0001503;multicellular organismal process#GO:0032501;tissue development#GO:0009888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000045743.1|UniProtKB=A0A5F8HBW8 A0A5F8HBW8 PTHR11593:SF10 60S RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN UL22 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000018920.3|UniProtKB=A0A5F8GTE7 A0A5F8GTE7 S100A11 PTHR11639:SF60 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A11 calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;extracellular region#GO:0005576 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000039911.1|UniProtKB=K7E0D9 K7E0D9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000008917.5|UniProtKB=F7GL79 F7GL79 NEFH PTHR23214:SF1 NEUROFILAMENT TRIPLET H PROTEIN NEUROFILAMENT HEAVY POLYPEPTIDE structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 intermediate filament bundle assembly#GO:0045110;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;axon development#GO:0061564;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;system development#GO:0048731;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cell projection organization#GO:0030030;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cell development#GO:0048468 cytoskeleton#GO:0005856;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;neuron projection#GO:0043005;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;axon#GO:0030424;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000020656.4|UniProtKB=F7FXR0 F7FXR0 PTHR47968:SF83 CENTROMERE PROTEIN E CENTROMERE-ASSOCIATED PROTEIN E binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cell cycle#GO:0007049;cellular process#GO:0009987;microtubule-based movement#GO:0007018;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000019869.5|UniProtKB=K7E3N8 K7E3N8 ALX4 PTHR24329:SF322 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN ARISTALESS-LIKE 4 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000005047.3|UniProtKB=F7BEP2 F7BEP2 LOC100011378 PTHR19919:SF0 WD REPEAT CONTAINING PROTEIN DDB1- AND CUL4-ASSOCIATED FACTOR 7 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000011617.4|UniProtKB=F6Q2D7 F6Q2D7 PTHR24103:SF676 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 response to stimulus#GO:0050896;defense response to other organism#GO:0098542;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000004273.4|UniProtKB=F6TES4 F6TES4 LOC100020945 PTHR10476:SF19 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 1B2 endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;late endosome to vacuole transport#GO:0045324;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;late endosome#GO:0005770;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000018324.4|UniProtKB=F6PTG4 F6PTG4 PARP11 PTHR45740:SF4 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP11 pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000019082.3|UniProtKB=F7FNE6 F7FNE6 PTHR23245:SF31 TRNA METHYLTRANSFERASE TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3 HOMOLOG tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168 macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000025629.3|UniProtKB=F6XWH1 F6XWH1 YIPF2 PTHR12822:SF3 PROTEIN YIPF PROTEIN YIPF2 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000040439.1|UniProtKB=A0A5F8GGI5 A0A5F8GGI5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012388.3|UniProtKB=F7BZ82 F7BZ82 PTHR23339:SF74 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE CDC14B hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;organelle assembly#GO:0070925;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of cell cycle phase transition#GO:1901987;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;positive regulation of cell cycle#GO:0045787;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;cellular component assembly#GO:0022607;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cell projection assembly#GO:0030031;positive regulation of cellular process#GO:0048522;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 membraneless organelle#GO:0043228;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 protein phosphatase#PC00195;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000020398.4|UniProtKB=F7BZS2 F7BZS2 AMACR PTHR48228:SF8 SUCCINYL-COA--D-CITRAMALATE COA-TRANSFERASE ALPHA-METHYLACYL-COA RACEMASE isomerase activity#GO:0016853;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824 steroid metabolic process#GO:0008202;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 transferase#PC00220;metabolite interconversion enzyme#PC00262 Carnitine metabolism#P02733>Carnitine dehydratase#P02866;Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864 MONDO|Ensembl=ENSMODG00000019459.4|UniProtKB=F6RWP4 F6RWP4 MOCS2 PTHR23404:SF2 MOLYBDOPTERIN SYNTHASE RELATED MOLYBDOPTERIN SYNTHASE CATALYTIC SUBUNIT cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000044919.1|UniProtKB=F6WEJ6 F6WEJ6 GATC PTHR15004:SF0 GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;translation#GO:0006412;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000019074.4|UniProtKB=H9H7A1 H9H7A1 GCAT PTHR13693:SF105 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 transaminase#PC00216 MONDO|Ensembl=ENSMODG00000007944.4|UniProtKB=A0A5F8G263 A0A5F8G263 CDK17 PTHR24056:SF128 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 17 cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000024414.2|UniProtKB=F7GFT2 F7GFT2 JRKL PTHR19303:SF16 TRANSPOSON JERKY PROTEIN HOMOLOG-LIKE binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000002885.2|UniProtKB=A0A5F8G2B1 A0A5F8G2B1 LZIC PTHR47142:SF1 BETA-CATENIN-INTERACTING PROTEIN 1 BETA-CATENIN-INTERACTING PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515;beta-catenin binding#GO:0008013 negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000001239.4|UniProtKB=F7FX25 F7FX25 FGB PTHR19143:SF332 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN BETA CHAIN blood coagulation, fibrin clot formation#GO:0072378;cell activation#GO:0001775;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;protein metabolic process#GO:0019538;protein activation cascade#GO:0072376;cell-substrate adhesion#GO:0031589;regulation of biological quality#GO:0065008;wound healing#GO:0042060;primary metabolic process#GO:0044238;hemostasis#GO:0007599;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;metabolic process#GO:0008152;platelet aggregation#GO:0070527;macromolecule metabolic process#GO:0043170;platelet activation#GO:0030168;blood coagulation#GO:0007596;response to wounding#GO:0009611;response to stress#GO:0006950;cell-cell adhesion#GO:0098609;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;coagulation#GO:0050817;gene expression#GO:0010467;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;homotypic cell-cell adhesion#GO:0034109;biosynthetic process#GO:0009058;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Plasminogen activating cascade#P00050>Fibrin#P01253;Blood coagulation#P00011>Fibrin polymer cross-linked#P00443;Blood coagulation#P00011>Fibrinogen#P00406;Blood coagulation#P00011>Fibrin monomer#P00418 MONDO|Ensembl=ENSMODG00000013037.4|UniProtKB=F7GBM0 F7GBM0 TECTA PTHR46160:SF3 ALPHA-TECTORIN-RELATED ALPHA-TECTORIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000043455.1|UniProtKB=A0A5F8H444 A0A5F8H444 ALDH5A1 PTHR43353:SF14 SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 Gamma-aminobutyric acid synthesis#P04384>Succinic semialdehyde dehydrogenase#P04481;Aminobutyrate degradation#P02726>Succinate semi-aldehyde dehydrogenase#P02824 MONDO|Ensembl=ENSMODG00000017403.4|UniProtKB=F6SK92 F6SK92 S100A8 PTHR11639:SF149 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A8 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169 cellular process#GO:0009987;endothelial cell migration#GO:0043542;cell motility#GO:0048870;cell migration#GO:0016477 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000050003.1|UniProtKB=A0A5F8GA26 A0A5F8GA26 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000007059.4|UniProtKB=A0A5F8G601 A0A5F8G601 REXO5 PTHR12801:SF82 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 5 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;catalytic activity#GO:0003824;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 exoribonuclease#PC00099;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000015752.3|UniProtKB=F7AH19 F7AH19 TBC1D22A PTHR22957:SF255 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 22A GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000036723.1|UniProtKB=A0A5F8H263 A0A5F8H263 C15orf61 PTHR34651:SF1 SIMILAR TO ENSANGP00000021391 SIMILAR TO HUMAN CHROMOSOME 15 OPEN READING FRAME 61 MONDO|Ensembl=ENSMODG00000029550.2|UniProtKB=K7DZU9 K7DZU9 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000001583.4|UniProtKB=F7BBM1 F7BBM1 PIK3C2B PTHR10048:SF30 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT BETA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 lipid biosynthetic process#GO:0008610;cell migration#GO:0016477;glycerophospholipid metabolic process#GO:0006650;intracellular signaling cassette#GO:0141124;biosynthetic process#GO:0009058;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;phosphatidylinositol phosphate biosynthetic process#GO:0046854 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137 Angiogenesis#P00005>PI3K#P00236;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;EGF receptor signaling pathway#P00018>PI3K#P00557;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;p53 pathway feedback loops 2#P04398>PI3K#P04661;FGF signaling pathway#P00021>PI3K#P00640;Integrin signalling pathway#P00034>PI3K#P00936;VEGF signaling pathway#P00056>PI3K#P01413;Axon guidance mediated by netrin#P00009>PI3K#P00363 MONDO|Ensembl=ENSMODG00000010496.4|UniProtKB=A0A5F8G915 A0A5F8G915 OAZ2 PTHR10279:SF6 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME 2 enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000051096.1|UniProtKB=A0A5F8HFT0 A0A5F8HFT0 LOC100010459 PTHR26453:SF156 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010414.4|UniProtKB=F7A6W7 F7A6W7 EDRF1 PTHR15000:SF1 ERYTHROID DIFFERENTIATION-RELATED FACTOR 1 ERYTHROID DIFFERENTIATION-RELATED FACTOR 1 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 MONDO|Ensembl=ENSMODG00000015204.5|UniProtKB=F7B9X7 F7B9X7 VARS1 PTHR11946:SF118 VALYL-TRNA SYNTHETASES VALINE--TRNA LIGASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000023063.2|UniProtKB=F7GKY8 F7GKY8 PTHR46751:SF6 EPPIN BPTI_KUNITZ INHIBITOR DOMAIN-CONTAINING PROTEIN regulation of microtubule-based process#GO:0032886;negative regulation of cellular process#GO:0048523;regulation of cell motility#GO:2000145;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of microtubule-based movement#GO:0060632;regulation of reproductive process#GO:2000241;regulation of cellular process#GO:0050794;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013;biological regulation#GO:0065007;regulation of locomotion#GO:0040012 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000018344.3|UniProtKB=F6PR73 F6PR73 RHNO1 PTHR35541:SF1 RAD9, HUS1, RAD1-INTERACTING NUCLEAR ORPHAN PROTEIN 1 RAD9, HUS1, RAD1-INTERACTING NUCLEAR ORPHAN PROTEIN 1 DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;DNA integrity checkpoint signaling#GO:0031570;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;negative regulation of cell cycle#GO:0045786;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;cellular response to stress#GO:0033554;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000009617.3|UniProtKB=A0A5F8GKB7 A0A5F8GKB7 MTX2 PTHR12289:SF38 METAXIN RELATED METAXIN-2 mitochondrion organization#GO:0007005;membrane organization#GO:0061024;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;protein-containing complex assembly#GO:0065003;protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein insertion into mitochondrial outer membrane#GO:0045040 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000046422.1|UniProtKB=A0A5F8G2U7 A0A5F8G2U7 GNAI2 PTHR10218:SF73 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-2 molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled adenosine receptor signaling pathway#GO:0001973;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell surface receptor signaling pathway#GO:0007166;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622 G-protein#PC00020;heterotrimeric G-protein#PC00117 Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;PI3 kinase pathway#P00048>Galpha#P01199;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Gonadotropin-releasing hormone receptor pathway#P06664>gnai#P06807;Enkephalin release#P05913>G-Protein (i)#P05974;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Opioid proenkephalin pathway#P05915>G-protein#P05994 MONDO|Ensembl=ENSMODG00000013955.4|UniProtKB=F6RT42 F6RT42 RSRP1 PTHR47622:SF1 ARGININE/SERINE-RICH PROTEIN 1 ARGININE_SERINE-RICH PROTEIN 1 MONDO|Ensembl=ENSMODG00000014584.3|UniProtKB=F7AS71 F7AS71 TENT5D PTHR12974:SF30 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5D adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;positive regulation of biosynthetic process#GO:0009891;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 MONDO|Ensembl=ENSMODG00000010225.4|UniProtKB=F6WLY7 F6WLY7 PLAT PTHR24264:SF42 TRYPSIN-RELATED TISSUE-TYPE PLASMINOGEN ACTIVATOR hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 protein maturation#GO:0051604;cell migration#GO:0016477;gene expression#GO:0010467;biosynthetic process#GO:0009058;biological regulation#GO:0065007;plasminogen activation#GO:0031639;signal transduction#GO:0007165;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;signaling#GO:0023052;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;zymogen activation#GO:0031638;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;protein metabolic process#GO:0019538;enzyme-linked receptor protein signaling pathway#GO:0007167;proteolysis#GO:0006508;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203 Blood coagulation#P00011>tPA#P00431;Plasminogen activating cascade#P00050>pro-tPA#P01249;Plasminogen activating cascade#P00050>tPA#P01257 MONDO|Ensembl=ENSMODG00000024238.2|UniProtKB=F6V0K6 F6V0K6 PTHR48018:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023459.3|UniProtKB=A0A5F8HA01 A0A5F8HA01 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005921.4|UniProtKB=A0A5F8GLC4 A0A5F8GLC4 CA13 PTHR18952:SF81 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 13-RELATED hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000002297.4|UniProtKB=H9H604 H9H604 HECW1 PTHR11254:SF79 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HECW1 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of dendrite development#GO:0050773;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128;regulation of developmental process#GO:0050793;primary metabolic process#GO:0044238;regulation of dendrite morphogenesis#GO:0048814;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000017800.3|UniProtKB=F7CFK5 F7CFK5 LOC100030101 PTHR45712:SF1 AGAP008170-PA NEPHROCAN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000010319.4|UniProtKB=F6S9Z9 F6S9Z9 NR3C1 PTHR48092:SF5 KNIRPS-RELATED PROTEIN-RELATED GLUCOCORTICOID RECEPTOR sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;cellular response to steroid hormone stimulus#GO:0071383;cellular response to stimulus#GO:0051716;steroid hormone receptor signaling pathway#GO:0043401;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;intracellular receptor signaling pathway#GO:0030522;response to steroid hormone#GO:0048545;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 Gonadotropin-releasing hormone receptor pathway#P06664>GR#P06810 MONDO|Ensembl=ENSMODG00000018941.4|UniProtKB=A0A5F8GHN8 A0A5F8GHN8 TMEM63B PTHR13018:SF38 PROBABLE MEMBRANE PROTEIN DUF221-RELATED MECHANOSENSITIVE CATION CHANNEL TMEM63B channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion-gated channel activity#GO:0022839 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000047885.1|UniProtKB=A0A5F8GKG6 A0A5F8GKG6 TXNDC15 PTHR14684:SF2 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 15 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 15 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929 MONDO|Gene=LHB|UniProtKB=Q95J85 Q95J85 LHB PTHR11515:SF11 GLYCOPROTEIN HORMONE BETA CHAIN LUTROPIN SUBUNIT BETA signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 anatomical structure development#GO:0048856;cell communication#GO:0007154;reproductive system development#GO:0061458;system development#GO:0048731;female gonad development#GO:0008585;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;reproductive process#GO:0022414;reproductive structure development#GO:0048608;signaling#GO:0023052;developmental process involved in reproduction#GO:0003006;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;multicellular organismal process#GO:0032501;gonad development#GO:0008406;biological regulation#GO:0065007;sex differentiation#GO:0007548;cellular process#GO:0009987;signal transduction#GO:0007165 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>LHbeta#G06688;Gonadotropin-releasing hormone receptor pathway#P06664>3' LHbeta#G06903;Gonadotropin-releasing hormone receptor pathway#P06664>5' LHbeta#G06889;Gonadotropin-releasing hormone receptor pathway#P06664>LHbeta#P06751 MONDO|Ensembl=ENSMODG00000010628.4|UniProtKB=F7DP31 F7DP31 PTHR24377:SF975 IP01015P-RELATED ZINC FINGER PROTEIN 883-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025136.2|UniProtKB=F7D5Y7 F7D5Y7 PTHR16083:SF8 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 10 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 striated muscle cell differentiation#GO:0051146;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;cardiac muscle cell differentiation#GO:0055007;heart development#GO:0007507;tissue development#GO:0009888;multicellular organismal process#GO:0032501;cellular process#GO:0009987;muscle tissue development#GO:0060537;system development#GO:0048731;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;circulatory system development#GO:0072359;cell differentiation#GO:0030154;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;contractile muscle fiber#GO:0043292;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013609.4|UniProtKB=K7E5Z1 K7E5Z1 TDRD9 PTHR18934:SF113 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE TDRD9 binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000005162.4|UniProtKB=F7E8E1 F7E8E1 LOC103099394 PTHR11537:SF235 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 1-LIKE metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267 regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;metal ion transport#GO:0030001;action potential#GO:0001508 monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;axon terminus#GO:0043679;neuron projection membrane#GO:0032589;voltage-gated potassium channel complex#GO:0008076;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;neuronal cell body#GO:0043025;neuron projection terminus#GO:0044306;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;protein-containing complex#GO:0032991;cell leading edge#GO:0031252;presynapse#GO:0098793;neuron projection#GO:0043005;transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;postsynapse#GO:0098794;cell body#GO:0044297;cell projection membrane#GO:0031253;postsynaptic membrane#GO:0045211;leading edge membrane#GO:0031256 voltage-gated ion channel#PC00241;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000005976.4|UniProtKB=F6VZ48 F6VZ48 UBR5 PTHR46276:SF1 E3 UBIQUITIN-PROTEIN LIGASE UBR5 E3 UBIQUITIN-PROTEIN LIGASE UBR5 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;protein modification by small protein conjugation or removal#GO:0070647;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 Hedgehog signaling pathway#P00025>Ubiquitin ligase#P00693 MONDO|Ensembl=ENSMODG00000037893.1|UniProtKB=A0A5F8H8K9 A0A5F8H8K9 LOC100031110 PTHR24249:SF79 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 9 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000005405.2|UniProtKB=F7G613 F7G613 LCAT PTHR11440:SF18 LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED PHOSPHATIDYLCHOLINE-STEROL ACYLTRANSFERASE acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 acyltransferase#PC00042;transferase#PC00220 MONDO|Ensembl=ENSMODG00000009956.4|UniProtKB=F6Y8K9 F6Y8K9 CAT PTHR11465:SF9 CATALASE CATALASE oxidoreductase activity#GO:0016491;heme binding#GO:0020037;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;tetrapyrrole binding#GO:0046906;binding#GO:0005488 metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;response to oxygen-containing compound#GO:1901700;response to oxidative stress#GO:0006979;response to reactive oxygen species#GO:0000302;response to stress#GO:0006950;cellular process#GO:0009987;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to chemical#GO:0042221;hydrogen peroxide metabolic process#GO:0042743 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;microbody#GO:0042579;peroxisome#GO:0005777;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 peroxidase#PC00180 MONDO|Ensembl=ENSMODG00000050260.1|UniProtKB=A0A5F8GT55 A0A5F8GT55 GPR33 PTHR24225:SF5 CHEMOTACTIC RECEPTOR G PROTEIN-COUPLED RECEPTOR 33-RELATED signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005989.4|UniProtKB=F6SL97 F6SL97 NEK9 PTHR44535:SF1 PROTEIN CBG16200 SERINE_THREONINE-PROTEIN KINASE NEK9 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000040904.1|UniProtKB=A0A5F8H3S5 A0A5F8H3S5 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000023604.2|UniProtKB=F7EXF5 F7EXF5 PTHR11627:SF1 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE A lyase activity#GO:0016829;fructose-bisphosphate aldolase activity#GO:0004332;aldehyde-lyase activity#GO:0016832;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside diphosphate metabolic process#GO:0009132;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 aldolase#PC00044;lyase#PC00144 Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959;Glycolysis#P00024>Aldolase#P00679 MONDO|Ensembl=ENSMODG00000025202.2|UniProtKB=F7BG29 F7BG29 SLC25A51 PTHR46131:SF2 SD08549P MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER SLC25A51-RELATED organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;purine nucleotide transmembrane transporter activity#GO:0015216;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;cellular process#GO:0009987;nitrogen compound transport#GO:0071705 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000016841.4|UniProtKB=F6R1Z3 F6R1Z3 OPTN PTHR31553:SF2 NF-KAPPA-B ESSENTIAL MODULATOR OPTINEURIN K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;modification-dependent protein binding#GO:0140030;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;protein binding#GO:0005515 regulation of response to stimulus#GO:0048583;protein localization to Golgi apparatus#GO:0034067;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;localization#GO:0051179;regulation of biological process#GO:0050789;Golgi organization#GO:0007030;cellular component organization#GO:0016043;regulation of cell communication#GO:0010646;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Huntington disease#P00029>FIP-2#P00772 MONDO|Ensembl=ENSMODG00000046829.1|UniProtKB=F6V1E4 F6V1E4 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000046751.1|UniProtKB=F7B023 F7B023 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009409.4|UniProtKB=F7AKQ5 F7AKQ5 SLC5A12 PTHR42985:SF15 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 2 symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monocarboxylic acid transmembrane transporter activity#GO:0008028 sodium ion transport#GO:0006814;transport#GO:0006810;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000005029.6|UniProtKB=F7FYD1 F7FYD1 PTHR24345:SF43 SERINE/THREONINE-PROTEIN KINASE PLK INACTIVE SERINE_THREONINE-PROTEIN KINASE PLK5 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 organelle disassembly#GO:1903008;regulation of mitotic cell cycle phase transition#GO:1901990;cellular component disassembly#GO:0022411;negative regulation of mitotic cell cycle#GO:0045930;regulation of G1/S transition of mitotic cell cycle#GO:2000045;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;mitotic spindle organization#GO:0007052;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;microtubule-based process#GO:0007017;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;endomembrane system organization#GO:0010256;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;intracellular signal transduction#GO:0035556;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;regulation of cell cycle G1/S phase transition#GO:1902806;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;Golgi organization#GO:0007030;cellular response to stimulus#GO:0051716;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346 spindle pole#GO:0000922;chromosome#GO:0005694;kinetochore#GO:0000776;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;membraneless organelle#GO:0043228 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000012654.4|UniProtKB=F6WDM2 F6WDM2 SYNE3 PTHR47535:SF2 MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G NESPRIN-3 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 establishment of organelle localization#GO:0051656;nuclear migration#GO:0007097;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;organelle localization#GO:0051640;intracellular transport#GO:0046907;transport#GO:0006810 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;nuclear protein-containing complex#GO:0140513;nuclear membrane#GO:0031965;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;membrane#GO:0016020;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000010894.4|UniProtKB=F7FJ52 F7FJ52 ZNF703 PTHR12522:SF2 ZINC-FINGER PROTEIN NOLZ1-RELATED ZINC FINGER PROTEIN 703 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000019564.4|UniProtKB=F6R8C1 F6R8C1 POLG PTHR10267:SF0 DNA POLYMERASE SUBUNIT GAMMA-1 DNA POLYMERASE SUBUNIT GAMMA-1 DNA-directed DNA polymerase activity#GO:0003887;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;DNA exonuclease activity#GO:0004529;transferase activity#GO:0016740 DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;mitochondrial DNA metabolic process#GO:0032042;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular process#GO:0009987 DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA-directed DNA polymerase#PC00018 MONDO|Ensembl=ENSMODG00000043641.1|UniProtKB=A0A5F8G2A9 A0A5F8G2A9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000037576.1|UniProtKB=A0A5F8GLU6 A0A5F8GLU6 LOC103094101 PTHR23226:SF425 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 24 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018439.4|UniProtKB=F6XBN5 F6XBN5 HDHD5 PTHR14269:SF17 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING 5 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000010950.4|UniProtKB=F7BCN6 F7BCN6 CAB39L PTHR10182:SF9 CALCIUM-BINDING PROTEIN 39-RELATED CALCIUM-BINDING PROTEIN 39-LIKE kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 MONDO|Ensembl=ENSMODG00000027668.2|UniProtKB=K7E4G4 K7E4G4 NSMCE2 PTHR21330:SF1 E3 SUMO-PROTEIN LIGASE NSE2 E3 SUMO-PROTEIN LIGASE NSE2 SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;protein sumoylation#GO:0016925;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;recombinational repair#GO:0000725;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein modification process#GO:0036211;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;condensed chromosome#GO:0000793;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000016898.3|UniProtKB=F6Y1F0 F6Y1F0 PTHR22803:SF116 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED REGENERATING ISLET-DERIVED PROTEIN 3-GAMMA receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function activator activity#GO:0140677 response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;response to nitrogen compound#GO:1901698;regulation of cell population proliferation#GO:0042127;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to oxygen-containing compound#GO:1901700;immune system process#GO:0002376;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;response to other organism#GO:0051707;response to chemical#GO:0042221;defense response to other organism#GO:0098542;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to hormone#GO:0009725;response to external stimulus#GO:0009605;defense response#GO:0006952;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000015750.3|UniProtKB=F7AH62 F7AH62 TMEM214 PTHR13448:SF0 TRANSMEMBRANE PROTEIN 214 TRANSMEMBRANE PROTEIN 214 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000005792.4|UniProtKB=F6XFW3 F6XFW3 METTL22 PTHR23108:SF0 METHYLTRANSFERASE-RELATED METHYLTRANSFERASE-LIKE PROTEIN 22 methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000004326.4|UniProtKB=F6X6V5 F6X6V5 CNN3 PTHR47385:SF17 CALPONIN CALPONIN-3 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 MONDO|Ensembl=ENSMODG00000037815.1|UniProtKB=A0A5F8HK73 A0A5F8HK73 LOC100016579 PTHR24024:SF13 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A PULMONARY SURFACTANT-ASSOCIATED PROTEIN A1 signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089 regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;positive regulation of endocytosis#GO:0045807;biological regulation#GO:0065007;response to other organism#GO:0051707;complement activation#GO:0006956;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;immune system process#GO:0002376;positive regulation of cellular component organization#GO:0051130;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of transport#GO:0051049;humoral immune response#GO:0006959;regulation of endocytosis#GO:0030100;immune effector process#GO:0002252;defense response to other organism#GO:0098542;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of transport#GO:0051050 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211;surfactant#PC00212 MONDO|Ensembl=ENSMODG00000050187.1|UniProtKB=A0A5F8G5D3 A0A5F8G5D3 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000012173.3|UniProtKB=F7CY79 F7CY79 PTHR17408:SF11 HISTONE RNA HAIRPIN-BINDING PROTEIN HISTONE RNA HAIRPIN-BINDING PROTEIN mRNA binding#GO:0003729;binding#GO:0005488;pre-mRNA binding#GO:0036002;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 localization#GO:0051179;RNA metabolic process#GO:0016070;nucleic acid transport#GO:0050657;nucleic acid biosynthetic process#GO:0141187;establishment of RNA localization#GO:0051236;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule localization#GO:0033036;mRNA processing#GO:0006397;nitrogen compound transport#GO:0071705 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000008954.2|UniProtKB=F7GCP3 F7GCP3 PTHR47507:SF7 BARRIER TO AUTOINTEGRATION FACTOR 2 BARRIER-TO-AUTOINTEGRATION FACTOR binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000023951.2|UniProtKB=A0A5F8HI83 A0A5F8HI83 TRIL PTHR45617:SF20 LEUCINE RICH REPEAT FAMILY PROTEIN TLR4 INTERACTOR WITH LEUCINE RICH REPEATS scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000024937.2|UniProtKB=F6VUA1 F6VUA1 PTHR10969:SF16 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN-LIKE 3 phospholipid binding#GO:0005543;ubiquitin-like protein ligase binding#GO:0044389;GABA receptor binding#GO:0050811;ubiquitin protein ligase binding#GO:0031625;enzyme binding#GO:0019899;signaling receptor binding#GO:0005102;binding#GO:0005488;lipid binding#GO:0008289;protein binding#GO:0005515 cellular component assembly#GO:0022607;macroautophagy#GO:0016236;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;organelle organization#GO:0006996;response to stress#GO:0006950;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;cellular response to starvation#GO:0009267;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;cellular response to nutrient levels#GO:0031669;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein-containing complex disassembly#GO:0032984;response to starvation#GO:0042594;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;cellular component disassembly#GO:0022411;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;organelle assembly#GO:0070925;cellular response to stress#GO:0033554 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;autophagosome membrane#GO:0000421;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774;intracellular organelle#GO:0043229;autophagosome#GO:0005776 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000002543.3|UniProtKB=F7ALX5 F7ALX5 KLHDC7A PTHR45972:SF1 BTB_2 DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 7A MONDO|Ensembl=ENSMODG00000008748.2|UniProtKB=F6PSI3 F6PSI3 GPR146 PTHR24226:SF3 G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1 G PROTEIN-COUPLED RECEPTOR 146 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000008238.4|UniProtKB=F6ZXR1 F6ZXR1 PRXL2B PTHR28630:SF29 FAMILY NOT NAMED PROSTAMIDE_PROSTAGLANDIN F SYNTHASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 prostaglandin metabolic process#GO:0006693;oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;unsaturated fatty acid biosynthetic process#GO:0006636;icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;icosanoid metabolic process#GO:0006690 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000028671.2|UniProtKB=A0A5F8G3H6 A0A5F8G3H6 PTHR11738:SF199 MHC CLASS I NK CELL RECEPTOR IG-LIKE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000019714.2|UniProtKB=F6XMG7 F6XMG7 LOC100619039 PTHR48001:SF106 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1L6 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009395.4|UniProtKB=F7CPD5 F7CPD5 DCT PTHR11474:SF4 TYROSINASE FAMILY MEMBER L-DOPACHROME TAUTOMERASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;oxidoreductase activity#GO:0016491 regulation of biological process#GO:0050789;phenol-containing compound metabolic process#GO:0018958;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;positive regulation of cell population proliferation#GO:0008284;cell differentiation#GO:0030154;central nervous system development#GO:0007417;positive regulation of nervous system development#GO:0051962;forebrain development#GO:0030900;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;melanin biosynthetic process#GO:0042438;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;developmental pigmentation#GO:0048066;phenol-containing compound biosynthetic process#GO:0046189;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;head development#GO:0060322;positive regulation of cell differentiation#GO:0045597;metabolic process#GO:0008152;secondary metabolite biosynthetic process#GO:0044550;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cell division#GO:0051301;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;cell population proliferation#GO:0008283;pigmentation#GO:0043473;system development#GO:0048731;regulation of cell population proliferation#GO:0042127;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;pigment metabolic process#GO:0042440;biosynthetic process#GO:0009058;biological regulation#GO:0065007;brain development#GO:0007420;multicellular organismal process#GO:0032501;pigment biosynthetic process#GO:0046148;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;secondary metabolic process#GO:0019748;neurogenesis#GO:0022008;cellular developmental process#GO:0048869 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;melanosome#GO:0042470;intracellular membrane-bounded organelle#GO:0043231 oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000020822.4|UniProtKB=F6RM47 F6RM47 PTHR44427:SF5 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10-LIKE cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000017247.3|UniProtKB=F6TKX0 F6TKX0 DNAJC12 PTHR44500:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 12 DNAJ HOMOLOG SUBFAMILY C MEMBER 12 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000002595.4|UniProtKB=F7G4X0 F7G4X0 RECK PTHR13487:SF3 SERINE PROTEASE INHIBITOR REVERSION-INDUCING CYSTEINE-RICH PROTEIN WITH KAZAL MOTIFS molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;multicellular organismal process#GO:0032501;developmental maturation#GO:0021700;tube development#GO:0035295;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure maturation#GO:0071695;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;angiogenesis#GO:0001525;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;sprouting angiogenesis#GO:0002040;regulation of signaling#GO:0023051;circulatory system development#GO:0072359;regulation of Wnt signaling pathway#GO:0030111;cellular component organization#GO:0016043;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000012015.3|UniProtKB=F7AM90 F7AM90 PTHR15138:SF18 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Huntington disease#P00029>TAFII130#P00806;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 MONDO|Ensembl=ENSMODG00000023391.2|UniProtKB=F6TPW7 F6TPW7 RPL13A PTHR11545:SF3 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 negative regulation of translation#GO:0017148;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000009733.3|UniProtKB=H9H6B8 H9H6B8 ENDOU PTHR12439:SF40 PLACENTAL PROTEIN 11-RELATED URIDYLATE-SPECIFIC ENDORIBONUCLEASE catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional gene silencing#GO:0016441;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000012841.2|UniProtKB=F7CTK4 F7CTK4 LOC100030271 PTHR26453:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G7 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001902.4|UniProtKB=A0A5F8H4H3 A0A5F8H4H3 LOC100015759 PTHR24271:SF97 KALLIKREIN-RELATED MAST CELL PROTEASE 2 ISOFORM X1 serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000017489.3|UniProtKB=F7FEV7 F7FEV7 PTHR46047:SF1 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 2 binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;protein binding#GO:0005515;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein phosphatase#PC00195;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000037216.1|UniProtKB=K7E0M8 K7E0M8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000023488.2|UniProtKB=F7EZS4 F7EZS4 PLEKHF1 PTHR46280:SF2 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 1 phosphatidylinositol binding#GO:0035091;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 regulation of cellular process#GO:0050794;regulation of autophagy#GO:0010506;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;localization#GO:0051179;cellular localization#GO:0051641;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;positive regulation of autophagy#GO:0010508;organelle organization#GO:0006996;regulation of metabolic process#GO:0019222;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;positive regulation of catabolic process#GO:0009896;establishment of localization#GO:0051234;vesicle organization#GO:0016050;endosome organization#GO:0007032;regulation of catabolic process#GO:0009894;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737;lytic vacuole#GO:0000323 MONDO|Ensembl=ENSMODG00000015579.3|UniProtKB=F6ZV84 F6ZV84 EIF3C PTHR13937:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3, SUBUNIT 8 EIF3S8 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C-RELATED translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 MONDO|Ensembl=ENSMODG00000025196.1|UniProtKB=F7C0D1 F7C0D1 ALDH1B1 PTHR11699:SF207 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER B1, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;catabolic process#GO:0009056;aldehyde catabolic process#GO:0046185 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 MONDO|Ensembl=ENSMODG00000019892.3|UniProtKB=F6W684 F6W684 HARBI1 PTHR22930:SF253 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED MONDO|Ensembl=ENSMODG00000013890.4|UniProtKB=A0A5F8GRT2 A0A5F8GRT2 DGKI PTHR11255:SF92 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE IOTA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 neutral lipid metabolic process#GO:0006638;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biological regulation#GO:0065007;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054 kinase#PC00137;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000017553.4|UniProtKB=F7E0X4 F7E0X4 MOXD1 PTHR10157:SF28 DOPAMINE BETA HYDROXYLASE RELATED DBH-LIKE MONOOXYGENASE PROTEIN 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 hydroxylase#PC00122 MONDO|Ensembl=ENSMODG00000008068.5|UniProtKB=A0A5F8GGZ0 A0A5F8GGZ0 ARID1B PTHR12656:SF11 BRG-1 ASSOCIATED FACTOR 250 BAF250 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 1B protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;binding#GO:0005488;chromatin binding#GO:0003682 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000011185.3|UniProtKB=F7E876 F7E876 HEXIM1 PTHR13469:SF7 HEXAMETHYLENE BISACETAMIDE INDUCIBLE 1 PROTEIN HEXIM1 enzyme inhibitor activity#GO:0004857;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase inhibitor activity#GO:0019210;binding#GO:0005488;nucleic acid binding#GO:0003676;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;snRNA binding#GO:0017069;RNA binding#GO:0003723 negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000050460.1|UniProtKB=A0A5F8HJT5 A0A5F8HJT5 LOC100019439 PTHR26450:SF156 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52R1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040170.1|UniProtKB=A0A5F8GSI6 A0A5F8GSI6 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000016071.3|UniProtKB=F7G9V3 F7G9V3 PURB PTHR12611:SF4 PUR-TRANSCRIPTIONAL ACTIVATOR TRANSCRIPTIONAL REGULATOR PROTEIN PUR-BETA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000041409.1|UniProtKB=A0A5F8G1Y7 A0A5F8G1Y7 PTHR46771:SF3 DETERIN BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5 mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;mitotic cytokinesis#GO:0000281;negative regulation of biological process#GO:0048519;cell cycle#GO:0007049;regulation of programmed cell death#GO:0043067;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell division#GO:0051301;cell cycle process#GO:0022402;cytoskeleton-dependent cytokinesis#GO:0061640;microtubule cytoskeleton organization#GO:0000226;cytokinesis#GO:0000910;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;negative regulation of cellular process#GO:0048523;chromosome segregation#GO:0007059;regulation of apoptotic process#GO:0042981 membraneless organelle#GO:0043228;spindle#GO:0005819;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;kinetochore#GO:0000776 Angiogenesis#P00005>Survivin#P00198 MONDO|Ensembl=ENSMODG00000028966.2|UniProtKB=K7E0U3 K7E0U3 RBP4 PTHR11873:SF2 RETINOL-BINDING PROTEIN 4 RETINOL-BINDING PROTEIN 4 small molecule binding#GO:0036094;binding#GO:0005488;alcohol binding#GO:0043178;lipid binding#GO:0008289 localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850;macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000019568.4|UniProtKB=F6R898 F6R898 FANCI PTHR21818:SF0 BC025462 PROTEIN FANCONI ANEMIA GROUP I PROTEIN positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;positive regulation of protein metabolic process#GO:0051247;cellular response to stress#GO:0033554;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of protein modification by small protein conjugation or removal#GO:1903320;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of protein modification process#GO:0031399;regulation of protein ubiquitination#GO:0031396;DNA damage response#GO:0006974;positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 nucleus#GO:0005634;DNA repair complex#GO:1990391;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000043575.1|UniProtKB=F7A7V1 F7A7V1 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000507.3|UniProtKB=F6Y630 F6Y630 HOXA1 PTHR45946:SF3 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN HOX-A1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000007067.4|UniProtKB=A0A5F8G7P8 A0A5F8G7P8 SENP3 PTHR12606:SF16 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 3 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190 MONDO|Ensembl=ENSMODG00000005026.4|UniProtKB=F7EQZ1 F7EQZ1 LRCH2 PTHR16083:SF11 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT AND CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN 2 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018308.4|UniProtKB=A0A5F8HH25 A0A5F8HH25 PTHR14453:SF89 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP14 NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763;transcription regulator activity#GO:0140110;glycosyltransferase activity#GO:0016757;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;transcription corepressor activity#GO:0003714;transferase activity#GO:0016740 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;negative regulation of immune response#GO:0050777;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;negative regulation of response to cytokine stimulus#GO:0060761;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of defense response#GO:0031348;regulation of macromolecule metabolic process#GO:0060255;regulation of cytokine-mediated signaling pathway#GO:0001959;negative regulation of cytokine-mediated signaling pathway#GO:0001960;negative regulation of innate immune response#GO:0045824;negative regulation of signal transduction#GO:0009968;negative regulation of response to external stimulus#GO:0032102;regulation of response to external stimulus#GO:0032101;regulation of response to cytokine stimulus#GO:0060759;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000037934.1|UniProtKB=A0A5F8HJV8 A0A5F8HJV8 PTHR12928:SF0 FRG1 PROTEIN PROTEIN FRG1 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;catalytic step 2 spliceosome#GO:0071013 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000010538.4|UniProtKB=F6ZF10 F6ZF10 ADAM12 PTHR11905:SF112 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 12 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000019181.4|UniProtKB=F7AX71 F7AX71 RASSF6 PTHR22738:SF3 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 6 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000925.4|UniProtKB=F7F837 F7F837 DYNC2H1 PTHR10676:SF352 DYNEIN HEAVY CHAIN FAMILY PROTEIN CYTOPLASMIC DYNEIN 2 HEAVY CHAIN 1 catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;microtubule motor activity#GO:0003777 cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;cilium-dependent cell motility#GO:0060285;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;intraciliary transport#GO:0042073;cell motility#GO:0048870;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;dynein complex#GO:0030286;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000012339.3|UniProtKB=F7E2D2 F7E2D2 TMEM51 PTHR16015:SF0 TRANSMEMBRANE PROTEIN 51 TRANSMEMBRANE PROTEIN 51 MONDO|Ensembl=ENSMODG00000008154.2|UniProtKB=F7ELC7 F7ELC7 HS2ST1 PTHR12129:SF17 HEPARAN SULFATE 2-O-SULFOTRANSFERASE HEPARAN SULFATE 2-O-SULFOTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000023227.2|UniProtKB=A0A5F8G7F2 A0A5F8G7F2 TENT5C PTHR12974:SF34 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5C adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA stabilization#GO:0043489;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 MONDO|Ensembl=ENSMODG00000016297.4|UniProtKB=F7ATH3 F7ATH3 PPM1L PTHR13832:SF827 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1L phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000008252.4|UniProtKB=F6ZX82 F6ZX82 NDUFAF7 PTHR12049:SF7 PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000017227.4|UniProtKB=A0A5F8GFH0 A0A5F8GFH0 UBAP2L PTHR16308:SF18 UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER UBIQUITIN-ASSOCIATED PROTEIN 2-LIKE cellular process#GO:0009987;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;homeostatic process#GO:0042592;multicellular organismal process#GO:0032501;cytoplasmic stress granule assembly#GO:0034063;cellular component assembly#GO:0022607;homeostasis of number of cells#GO:0048872;organelle assembly#GO:0070925;multicellular organismal-level homeostasis#GO:0048871;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;PcG protein complex#GO:0031519;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000004426.4|UniProtKB=A0A5F8GKX9 A0A5F8GKX9 PTHR10634:SF27 AN1-TYPE ZINC FINGER PROTEIN ZINC FINGER AN1-TYPE CONTAINING 5 MONDO|Ensembl=ENSMODG00000001972.4|UniProtKB=F6RIR8 F6RIR8 FBXO32 PTHR13123:SF6 LD30288P F-BOX ONLY PROTEIN 32 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238 ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000013685.3|UniProtKB=F6QQ47 F6QQ47 SPATA25 PTHR36857:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 25 SPERMATOGENESIS-ASSOCIATED PROTEIN 25 reproductive process#GO:0022414;male gamete generation#GO:0048232;gamete generation#GO:0007276;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;developmental process#GO:0032502;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283 MONDO|Ensembl=ENSMODG00000013756.4|UniProtKB=F6WS18 F6WS18 FZD9 PTHR11309:SF79 FRIZZLED FRIZZLED-9 Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;biological regulation#GO:0065007;signaling#GO:0023052;non-canonical Wnt signaling pathway#GO:0035567;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475 MONDO|Ensembl=ENSMODG00000017362.3|UniProtKB=F6VZR7 F6VZR7 PTHR44755:SF5 NATRIURETIC PEPTIDE RECEPTOR 3-RELATED GUANYLATE CYCLASE molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;peptide hormone binding#GO:0017046;signaling receptor activity#GO:0038023;hormone binding#GO:0042562;binding#GO:0005488 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000036829.1|UniProtKB=A0A5F8GPH5 A0A5F8GPH5 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000047925.1|UniProtKB=A0A5F8HE21 A0A5F8HE21 PTHR41694:SF8 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 11 POL PROTEIN-LIKE binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000681.2|UniProtKB=F6WME4 F6WME4 LOC100010000 PTHR24264:SF15 TRYPSIN-RELATED TRYPSIN peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000000713.4|UniProtKB=A0A5F8GYT6 A0A5F8GYT6 ADGRL2 PTHR12011:SF61 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR L2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009558.4|UniProtKB=F7BJK8 F7BJK8 PDGFB PTHR11633:SF2 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR SUBUNIT B binding#GO:0005488;signaling receptor binding#GO:0005102;growth factor receptor binding#GO:0070851;protein binding#GO:0005515 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;positive regulation of locomotion#GO:0040017;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of cell motility#GO:2000147;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;signaling#GO:0023052;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of ERK1 and ERK2 cascade#GO:0070372 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Angiogenesis#P00005>PDGF#P00224;PDGF signaling pathway#P00047>PDGF#P01170 MONDO|Ensembl=ENSMODG00000045245.1|UniProtKB=F7EG56 F7EG56 PPP1R7 PTHR45973:SF23 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 7 protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 cell cycle process#GO:0022402;cellular process#GO:0009987;chromosome segregation#GO:0007059;cell cycle#GO:0007049 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000011052.4|UniProtKB=K7E429 K7E429 SRSF4 PTHR23003:SF45 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE_ARGININE-RICH SPLICING FACTOR 4 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000005661.3|UniProtKB=F6VL22 F6VL22 PTHR19367:SF51 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 16 immune response#GO:0006955;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000007659.2|UniProtKB=A0A5F8HDL0 A0A5F8HDL0 PTHR31606:SF4 WW DOMAIN BINDING PROTEIN 2, ISOFORM E WW DOMAIN-BINDING PROTEIN 2 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;chromatin DNA binding#GO:0031490;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682 regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000016032.4|UniProtKB=A0A5F8GXZ1 A0A5F8GXZ1 PTHR11673:SF13 TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 5A-2 translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000048264.1|UniProtKB=A0A5F8HIR0 A0A5F8HIR0 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000036635.1|UniProtKB=A0A5F8HD58 A0A5F8HD58 LOC130455182 PTHR26452:SF310 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000005901.4|UniProtKB=F6XD73 F6XD73 ODF1 PTHR17125:SF2 OUTER DENSE FIBER PROTEIN 1 OUTER DENSE FIBER PROTEIN 1 cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000010009.4|UniProtKB=A0A5F8HEI5 A0A5F8HEI5 SLAMF9 PTHR12080:SF18 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE SLAM FAMILY MEMBER 9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;immune response#GO:0006955;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;leukocyte activation#GO:0045321;T cell activation#GO:0042110;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;immune system process#GO:0002376;cell activation#GO:0001775 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000010227.4|UniProtKB=A0A5F8GF46 A0A5F8GF46 LOC100027271 PTHR24221:SF251 ATP-BINDING CASSETTE SUB-FAMILY B ABC-TYPE XENOBIOTIC TRANSPORTER primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000037146.1|UniProtKB=A0A5F8GD60 A0A5F8GD60 PTHR23158:SF54 MELANOMA INHIBITORY ACTIVITY-RELATED TRANSPORT AND GOLGI ORGANIZATION PROTEIN 1 HOMOLOG protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;secretion by cell#GO:0032940;cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000048937.1|UniProtKB=A0A5F8GBW3 A0A5F8GBW3 PTHR19343:SF0 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 23_DELTA VARIABLE 6 antigen binding#GO:0003823;peptide binding#GO:0042277;binding#GO:0005488 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000014344.4|UniProtKB=A0A5F8HEJ0 A0A5F8HEJ0 C5orf24 PTHR31894:SF0 UPF0461 PROTEIN C5ORF24 UPF0461 PROTEIN C5ORF24 MONDO|Ensembl=ENSMODG00000017480.3|UniProtKB=F7C1D5 F7C1D5 LOC100022919 PTHR10880:SF48 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;chromatin#GO:0000785;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000006995.4|UniProtKB=F6XVA7 F6XVA7 ABCC8 PTHR24223:SF187 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000003171.3|UniProtKB=F6WDE3 F6WDE3 LOC100619259 PTHR26453:SF636 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2B8 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010499.3|UniProtKB=A0A5F8HKI7 A0A5F8HKI7 ZMAT4 PTHR46144:SF3 ZINC FINGER PROTEIN 385B-LIKE ZINC FINGER MATRIN-TYPE PROTEIN 4 MONDO|Ensembl=ENSMODG00000019070.4|UniProtKB=F7FZ90 F7FZ90 DLC1 PTHR12659:SF2 RHO-TYPE GTPASE ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 7 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 cellular component organization or biogenesis#GO:0071840;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;regulation of cell communication#GO:0010646;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 membrane microdomain#GO:0098857;cell junction#GO:0030054;anchoring junction#GO:0070161;membrane#GO:0016020;membrane raft#GO:0045121;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055 GTPase-activating protein#PC00257;G-protein modulator#PC00022 PDGF signaling pathway#P00047>Rho#P01174 MONDO|Ensembl=ENSMODG00000025518.3|UniProtKB=F6VJ55 F6VJ55 PTHR16108:SF2 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 40 MONDO|Ensembl=ENSMODG00000013897.3|UniProtKB=A0A5F8H9J8 A0A5F8H9J8 UBE2D1 PTHR24068:SF36 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 D1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000003458.4|UniProtKB=A0A5F8GI90 A0A5F8GI90 PINLYP PTHR20914:SF50 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 PHOSPHOLIPASE A2 INHIBITOR AND LY6_PLAUR DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000049902.1|UniProtKB=A0A5F8GT11 A0A5F8GT11 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000007018.4|UniProtKB=F6UX97 F6UX97 MRPS25 PTHR13274:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S25 SMALL RIBOSOMAL SUBUNIT PROTEIN MS25 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000048400.1|UniProtKB=F7GCD4 F7GCD4 LOC100027731 PTHR11766:SF0 TYROSYL-TRNA SYNTHETASE TYROSINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;translation#GO:0006412;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000012107.4|UniProtKB=F7FUE0 F7FUE0 PEAK1 PTHR22972:SF5 SERINE/THREONINE PROTEIN KINASE INACTIVE TYROSINE-PROTEIN KINASE PEAK1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of biological process#GO:0050789;regulation of cell motility#GO:2000145;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of locomotion#GO:0040012 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cell junction#GO:0030054;membraneless organelle#GO:0043228;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000012026.4|UniProtKB=F7AM02 F7AM02 PDK2 PTHR11947:SF15 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 2, MITOCHONDRIAL protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biosynthetic process#GO:0009889;regulation of lipid metabolic process#GO:0019216;regulation of carbohydrate metabolic process#GO:0006109 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 TCA cycle#P00051>Pyruvate Dehydrogenase#P01266 MONDO|Ensembl=ENSMODG00000001093.4|UniProtKB=F7GHM2 F7GHM2 KPNA7 PTHR23316:SF11 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-8 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000012063.4|UniProtKB=A0A5F8GKH5 A0A5F8GKH5 PTHR10166:SF6 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-1 channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;calcium channel complex#GO:0034704;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transporter complex#GO:1990351;sarcolemma#GO:0042383;transmembrane transporter complex#GO:1902495 voltage-gated ion channel#PC00241;transporter#PC00227 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>Ca2+ channel#P01081 MONDO|Ensembl=ENSMODG00000025480.3|UniProtKB=F6QZ81 F6QZ81 RFX8 PTHR12619:SF24 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX8 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000015193.4|UniProtKB=A0A5F8H5X7 A0A5F8H5X7 DNPEP PTHR28570:SF18 ASPARTYL AMINOPEPTIDASE ASPARTYL AMINOPEPTIDASE metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000022877.2|UniProtKB=F6Q2I7 F6Q2I7 PTHR26450:SF23 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E5 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000041246.1|UniProtKB=A0A5F8H2H4 A0A5F8H2H4 PTHR48520:SF1 SECRETED PROTEIN SECRETED PROTEIN MONDO|Ensembl=ENSMODG00000013539.4|UniProtKB=F7CM23 F7CM23 SRSF3 PTHR23147:SF121 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 3 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000013886.4|UniProtKB=F6VT24 F6VT24 SLC20A1 PTHR11101:SF46 PHOSPHATE TRANSPORTER SODIUM-DEPENDENT PHOSPHATE TRANSPORTER 1 metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;phosphate transmembrane transporter activity#GO:0005315 phosphate ion transport#GO:0006817;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000020724.4|UniProtKB=A0A5F8GPB8 A0A5F8GPB8 ADGRL3 PTHR12011:SF60 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR L3 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008302.4|UniProtKB=F7FTV6 F7FTV6 MN1 PTHR15821:SF0 PROTEIN MN1 TRANSCRIPTIONAL ACTIVATOR MN1 MONDO|Ensembl=ENSMODG00000004463.4|UniProtKB=F7CLP5 F7CLP5 ACO1 PTHR11670:SF32 ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER CYTOPLASMIC ACONITATE HYDRATASE hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824;iron-sulfur cluster binding#GO:0051536;RNA binding#GO:0003723;lyase activity#GO:0016829;binding#GO:0005488;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;carboxylic acid metabolic process#GO:0019752;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 Methylcitrate cycle#P02754>Aconitase#P03028 MONDO|Ensembl=ENSMODG00000046229.1|UniProtKB=A0A5F8HIP6 A0A5F8HIP6 LOC100619397 PTHR24393:SF100 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 345-RELATED transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000012144.5|UniProtKB=F7DHY8 F7DHY8 KDM3B PTHR12549:SF8 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN LYSINE-SPECIFIC DEMETHYLASE 3B histone demethylase activity#GO:0032452;chromatin DNA binding#GO:0031490;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;protein demethylase activity#GO:0140457;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;histone modifying activity#GO:0140993;DNA binding#GO:0003677 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000006375.3|UniProtKB=F7GCQ3 F7GCQ3 ENTPD6 PTHR11782:SF99 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 6 ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 metabolic process#GO:0008152;nucleoside diphosphate metabolic process#GO:0009132;organophosphate catabolic process#GO:0046434;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139 membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 nucleotide phosphatase#PC00173;hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000048738.1|UniProtKB=K7E5W1 K7E5W1 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000002636.4|UniProtKB=A0A5F8GDH3 A0A5F8GDH3 KCNH1 PTHR10217:SF530 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED DELAYED RECTIFIER POTASSIUM CHANNEL KCNH1 channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215 cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;metal ion transport#GO:0030001;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular monoatomic ion homeostasis#GO:0006873 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000012562.3|UniProtKB=F6PLE8 F6PLE8 CTNNAL1 PTHR46342:SF1 ALPHA-CATULIN ALPHA-CATULIN intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 Wnt signaling pathway#P00057>alpha-catenin#P01471 MONDO|Ensembl=ENSMODG00000013466.4|UniProtKB=F7FYK7 F7FYK7 PI16 PTHR10334:SF613 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR 16 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000000390.4|UniProtKB=F6R8D1 F6R8D1 MCOLN2 PTHR12127:SF4 MUCOLIPIN MUCOLIPIN-2 channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated calcium channel activity#GO:0099604;calcium ion transmembrane transporter activity#GO:0015085;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000013459.4|UniProtKB=F7FYZ5 F7FYZ5 DUSP28 PTHR45961:SF7 IP21249P DUAL SPECIFICITY PHOSPHATASE 28 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000029425.2|UniProtKB=F6Z2J3 F6Z2J3 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000001177.5|UniProtKB=F7GHE4 F7GHE4 BMS1 PTHR12858:SF2 RIBOSOME BIOGENESIS PROTEIN RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleic acid binding#GO:0003676;GTPase activity#GO:0003924;RNA binding#GO:0003723;hydrolase activity#GO:0016787 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;preribosome#GO:0030684;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;90S preribosome#GO:0030686;small-subunit processome#GO:0032040;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000003098.4|UniProtKB=F6PIV2 F6PIV2 SH3TC1 PTHR22647:SF3 SH3 DOMAIN AND TETRATRICOPEPTIDE REPEATS CONTAINING PROTEIN SH3 DOMAIN AND TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000008117.4|UniProtKB=F7G5H0 F7G5H0 RER1 PTHR10743:SF0 PROTEIN RER1 PROTEIN RER1 cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;protein localization to organelle#GO:0033365;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000023795.2|UniProtKB=F6VBZ3 F6VBZ3 LOC100009728 PTHR13042:SF0 UBIQUITIN-LIKE PROTEIN 5 UBIQUITIN-LIKE PROTEIN 5 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000013588.3|UniProtKB=F7AVT6 F7AVT6 PTHR23239:SF106 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 39 structural molecule activity#GO:0005198 cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;organelle organization#GO:0006996;morphogenesis of an epithelium#GO:0002009;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000006034.5|UniProtKB=A0A5F8H4B4 A0A5F8H4B4 CHKB PTHR22603:SF35 CHOLINE/ETHANOALAMINE KINASE CHOLINE_ETHANOLAMINE KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 MONDO|Ensembl=ENSMODG00000021030.3|UniProtKB=F6QYV3 F6QYV3 CRYAA PTHR45640:SF14 HEAT SHOCK PROTEIN HSP-12.2-RELATED ALPHA-CRYSTALLIN A CHAIN negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;response to heat#GO:0009408;sensory system development#GO:0048880;response to stress#GO:0006950;response to temperature stimulus#GO:0009266;gene expression#GO:0010467;protein maturation#GO:0051604;lens development in camera-type eye#GO:0002088;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;response to abiotic stimulus#GO:0009628;protein folding#GO:0006457;response to stimulus#GO:0050896;animal gross anatomical part developmental process#GO:0160108;eye development#GO:0001654;protein refolding#GO:0042026;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;multicellular organismal process#GO:0032501;developmental process#GO:0032502;sensory organ development#GO:0007423;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;visual system development#GO:0150063;regulation of cellular process#GO:0050794;camera-type eye development#GO:0043010;system development#GO:0048731;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 MONDO|Ensembl=ENSMODG00000019062.4|UniProtKB=H9H793 H9H793 SOX10 PTHR45803:SF6 SOX100B TRANSCRIPTION FACTOR SOX-10 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;stem cell differentiation#GO:0048863;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;neural crest cell development#GO:0014032;cell migration#GO:0016477;tissue development#GO:0009888;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;mesenchyme development#GO:0060485;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell motility#GO:0048870;stem cell development#GO:0048864;tissue morphogenesis#GO:0048729;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;neural crest cell migration#GO:0001755;cellular process#GO:0009987;nervous system development#GO:0007399;neural crest cell differentiation#GO:0014033;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;mesenchymal cell differentiation#GO:0048762;multicellular organism development#GO:0007275;animal organ development#GO:0048513;morphogenesis of an epithelium#GO:0002009;negative regulation of biological process#GO:0048519;peripheral nervous system development#GO:0007422;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000040159.1|UniProtKB=A0A5F8GBM6 A0A5F8GBM6 PTHR23411:SF39 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 1-RELATED protein binding#GO:0005515;antigen binding#GO:0003823;binding#GO:0005488;signaling receptor binding#GO:0005102 response to bacterium#GO:0009617;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955;complement activation#GO:0006956;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;antibacterial humoral response#GO:0019731;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;immune effector process#GO:0002252;defense response to other organism#GO:0098542;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000009211.4|UniProtKB=F6YZ69 F6YZ69 PTGIR PTHR11866:SF7 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTACYCLIN RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;negative regulation of cellular process#GO:0048523;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;biological regulation#GO:0065007;negative regulation of cell population proliferation#GO:0008285;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of biological quality#GO:0065008;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 MONDO|Ensembl=ENSMODG00000009940.3|UniProtKB=F6R7Z7 F6R7Z7 CCDC47 PTHR12883:SF0 ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED PAT COMPLEX SUBUNIT CCDC47 cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;protein folding chaperone complex#GO:0101031;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000003331.4|UniProtKB=A0A5F8H1A5 A0A5F8H1A5 GPS1 PTHR14145:SF2 26S PROTESOME SUBUNIT 6 COP9 SIGNALOSOME COMPLEX SUBUNIT 1 primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;regulation of protein stability#GO:0031647;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000000013.4|UniProtKB=A0A5F8GF82 A0A5F8GF82 CLEC5A PTHR47536:SF1 C-TYPE LECTIN DOMAIN FAMILY 5 MEMBER A C-TYPE LECTIN DOMAIN FAMILY 5 MEMBER A virus receptor activity#GO:0001618;protein binding#GO:0005515;binding#GO:0005488 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 MONDO|Ensembl=ENSMODG00000013906.5|UniProtKB=A0A5F8GM57 A0A5F8GM57 DBNL PTHR10829:SF12 CORTACTIN AND DREBRIN DREBRIN-LIKE PROTEIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254 supramolecular fiber#GO:0099512;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin filament#GO:0005884;cytoskeleton#GO:0005856;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;supramolecular complex#GO:0099080;lamellipodium#GO:0030027;supramolecular polymer#GO:0099081;glutamatergic synapse#GO:0098978;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000010946.4|UniProtKB=F7EP16 F7EP16 PTHR43570:SF15 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE, DIMERIC NADP-PREFERRING catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 MONDO|Ensembl=ENSMODG00000015212.4|UniProtKB=F6V4H7 F6V4H7 MPP3 PTHR23122:SF33 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 3 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000041760.1|UniProtKB=A0A5F8GTM3 A0A5F8GTM3 RAPSN PTHR46574:SF1 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;positive regulation of synaptic transmission#GO:0050806;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;synaptic signaling#GO:0099536 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuromuscular junction#GO:0031594;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000012521.4|UniProtKB=A0A5F8G694 A0A5F8G694 VRK3 PTHR11909:SF99 CASEIN KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE VRK3 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;response to stress#GO:0006950;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000012543.4|UniProtKB=F6PYW9 F6PYW9 TRIM14 PTHR25465:SF11 B-BOX DOMAIN CONTAINING TRIPARTITE MOTIF CONTAINING 14 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000011644.4|UniProtKB=F6TIP4 F6TIP4 MID2 PTHR24099:SF12 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE MID2-RELATED tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 intracellular protein localization#GO:0008104;protein localization to microtubule cytoskeleton#GO:0072698;localization#GO:0051179;protein localization to organelle#GO:0033365;macromolecule localization#GO:0033036;protein localization to cytoskeleton#GO:0044380 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000040593.1|UniProtKB=A0A5F8HJE0 A0A5F8HJE0 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000038171.1|UniProtKB=A0A5F8GMG5 A0A5F8GMG5 CNIH3 PTHR12290:SF12 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 3 chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234 endomembrane system#GO:0012505;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;membrane#GO:0016020;neuron projection#GO:0043005;cell junction#GO:0030054;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;dendrite#GO:0030425;endoplasmic reticulum subcompartment#GO:0098827;dendritic tree#GO:0097447;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000011111.5|UniProtKB=A0A5F8HIC1 A0A5F8HIC1 TRAK1 PTHR15751:SF11 TRAFFICKING KINESIN-BINDING PROTEIN TRAFFICKING KINESIN-BINDING PROTEIN 1 cytoskeletal protein binding#GO:0008092;GABA receptor binding#GO:0050811;binding#GO:0005488;myosin binding#GO:0017022;signaling receptor binding#GO:0005102;protein binding#GO:0005515 microtubule-based movement#GO:0007018;endosome to lysosome transport#GO:0008333;organelle localization#GO:0051640;system development#GO:0048731;localization#GO:0051179;anatomical structure development#GO:0048856;vesicle localization#GO:0051648;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;developmental process#GO:0032502;vacuolar transport#GO:0007034;transport#GO:0006810;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;vesicle cytoskeletal trafficking#GO:0099518;mitochondrion localization#GO:0051646;neurogenesis#GO:0022008;transport along microtubule#GO:0010970;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;cell differentiation#GO:0030154;establishment of organelle localization#GO:0051656;protein targeting#GO:0006605;microtubule-based transport#GO:0099111;lysosomal transport#GO:0007041;animal gross anatomical part developmental process#GO:0160108;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;nervous system development#GO:0007399;vesicle-mediated transport#GO:0016192;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275 neuron projection#GO:0043005;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;mitochondrion#GO:0005739;vesicle#GO:0031982;intracellular vesicle#GO:0097708;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000003888.4|UniProtKB=F7D7S3 F7D7S3 MROH7 PTHR23120:SF17 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 7 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000007344.3|UniProtKB=F7B0N6 F7B0N6 LOC100017147 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000051324.1|UniProtKB=A0A5F8GBV9 A0A5F8GBV9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010763.4|UniProtKB=F7FK66 F7FK66 VN2R598 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005003.4|UniProtKB=F7F719 F7F719 CAPN8 PTHR10183:SF374 CALPAIN CALPAIN-8 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 MONDO|Ensembl=ENSMODG00000027430.2|UniProtKB=K7E5V3 K7E5V3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000011690.2|UniProtKB=A0A5F8HHK4 A0A5F8HHK4 ARHGAP25 PTHR15228:SF20 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 25 enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 membrane organization#GO:0061024;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;transport#GO:0006810;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;phagocytosis#GO:0006909;actin filament organization#GO:0007015;establishment of localization#GO:0051234;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cellular process#GO:0009987;organelle organization#GO:0006996;negative regulation of signal transduction#GO:0009968;cytoskeleton organization#GO:0007010;membrane invagination#GO:0010324;regulation of small GTPase mediated signal transduction#GO:0051056;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;endocytosis#GO:0006897;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000007979.4|UniProtKB=F7D697 F7D697 PTHR10579:SF52 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000006367.4|UniProtKB=F7GCV3 F7GCV3 C2H6orf118 PTHR34916:SF1 GI:13385330 RIKEN CDNA 1700010I14 GENE MONDO|Ensembl=ENSMODG00000003014.3|UniProtKB=A0A5F8HE32 A0A5F8HE32 ARHGDIA PTHR10980:SF9 RHO GDP-DISSOCIATION INHIBITOR RHO GDP-DISSOCIATION INHIBITOR 1 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 intracellular signal transduction#GO:0035556;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000045113.1|UniProtKB=A0A5F8G537 A0A5F8G537 GORAB PTHR21470:SF29 RAB6-INTERACTING PROTEIN GORAB RAB6-INTERACTING GOLGIN non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000015907.4|UniProtKB=F6VED2 F6VED2 NCOA1 PTHR10684:SF1 NUCLEAR RECEPTOR COACTIVATOR NUCLEAR RECEPTOR COACTIVATOR 1 transcription coactivator activity#GO:0003713;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712;DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription regulator activity#GO:0140110;binding#GO:0005488 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of transcription by RNA polymerase II#GO:0045944 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000025309.2|UniProtKB=F7ENX1 F7ENX1 PTHR35827:SF2 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 3 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000006427.4|UniProtKB=F7EZ93 F7EZ93 DLG4 PTHR23119:SF33 DISCS LARGE DISKS LARGE HOMOLOG 4 protein binding#GO:0005515;structural constituent of synapse#GO:0098918;kinase binding#GO:0019900;binding#GO:0005488;signaling receptor binding#GO:0005102;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;structural molecule activity#GO:0005198 signaling#GO:0023052;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;receptor clustering#GO:0043113;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;nervous system development#GO:0007399;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell adhesion#GO:0098609;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;protein localization to synapse#GO:0035418;postsynapse organization#GO:0099173;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;system development#GO:0048731;anatomical structure development#GO:0048856;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;cell communication#GO:0007154;localization#GO:0051179;establishment or maintenance of bipolar cell polarity#GO:0061245;synapse organization#GO:0050808;localization within membrane#GO:0051668;trans-synaptic signaling#GO:0099537;establishment or maintenance of apical/basal cell polarity#GO:0035088;protein localization to cell junction#GO:1902414;biological regulation#GO:0065007;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;developmental process#GO:0032502;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072 postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;neuromuscular junction#GO:0031594;cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 scaffold/adaptor protein#PC00226 Huntington disease#P00029>PSD-95#P00789 MONDO|Ensembl=ENSMODG00000044237.1|UniProtKB=A0A5F8H4T5 A0A5F8H4T5 PTHR23087:SF12 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-14 binding#GO:0005488;chromatin binding#GO:0003682 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000024233.2|UniProtKB=F6VH92 F6VH92 ZNF770 PTHR24376:SF257 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 770 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000037418.1|UniProtKB=A0A5F8G2Z3 A0A5F8G2Z3 monDomV1R1273 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020303.4|UniProtKB=F7BFG2 F7BFG2 PRKAA1 PTHR24343:SF306 SERINE/THREONINE KINASE 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;intracellular protein localization#GO:0008104;positive regulation of catabolic process#GO:0009896;cellular response to glucose starvation#GO:0042149;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;response to nutrient levels#GO:0031667;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;localization#GO:0051179;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;negative regulation of TOR signaling#GO:0032007;negative regulation of TORC1 signaling#GO:1904262;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;negative regulation of signal transduction#GO:0009968;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;response to stimulus#GO:0050896 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 MONDO|Ensembl=ENSMODG00000015661.2|UniProtKB=F7EIH8 F7EIH8 SNX17 PTHR12431:SF16 SORTING NEXIN 17 AND 27 SORTING NEXIN-17 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;metabolic process#GO:0008152;intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810;macromolecule metabolic process#GO:0043170;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004930.3|UniProtKB=F7BGA2 F7BGA2 BFAR PTHR15898:SF21 BIFUNCTIONAL APOPTOSIS REGULATOR BIFUNCTIONAL APOPTOSIS REGULATOR aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 MONDO|Ensembl=ENSMODG00000010670.4|UniProtKB=F7CJW0 F7CJW0 KRIT1 PTHR13283:SF11 KREV INTERACTION TRAPPED 1-RELATED KREV INTERACTION TRAPPED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 anatomical structure development#GO:0048856;regulation of angiogenesis#GO:0045765;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;regulation of developmental process#GO:0050793;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of angiogenesis#GO:0016525;anterior/posterior axis specification#GO:0009948;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;regulation of vasculature development#GO:1901342;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;regulation of establishment or maintenance of cell polarity#GO:0032878;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000002849.3|UniProtKB=F7EIQ0 F7EIQ0 PTHR11905:SF120 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 1A-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;animal organ development#GO:0048513;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;male sex differentiation#GO:0046661;metabolic process#GO:0008152;development of primary male sexual characteristics#GO:0046546;gonad development#GO:0008406;multicellular organismal process#GO:0032501;male gonad development#GO:0008584;cellular process#GO:0009987;sex differentiation#GO:0007548;system development#GO:0048731;reproductive system development#GO:0061458;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;proteolysis#GO:0006508;animal gross anatomical part developmental process#GO:0160108;reproductive process#GO:0022414;reproductive structure development#GO:0048608;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006 plasma membrane region#GO:0098590;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000004228.5|UniProtKB=F6UBR2 F6UBR2 ZBTB37 PTHR24399:SF32 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 37 DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565 negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000013194.4|UniProtKB=F7FA71 F7FA71 KRT222 PTHR47082:SF1 KERATIN-LIKE PROTEIN KRT222 KERATIN-LIKE PROTEIN KRT222 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000006941.3|UniProtKB=F6RGE8 F6RGE8 PTPRE PTHR19134:SF499 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE EPSILON phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000015309.4|UniProtKB=F6XZ37 F6XZ37 SUDS3 PTHR21964:SF34 BREAST CANCER METASTASIS-SUPPRESSOR 1 SIN3 HISTONE DEACETYLASE COREPRESSOR COMPLEX COMPONENT SDS3 protein binding#GO:0005515;histone deacetylase binding#GO:0042826;enzyme binding#GO:0019899;binding#GO:0005488 negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000014945.4|UniProtKB=F7FI91 F7FI91 SLC25A30 PTHR45618:SF11 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED KIDNEY MITOCHONDRIAL CARRIER PROTEIN 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000012054.4|UniProtKB=F7GF84 F7GF84 ZNF644 PTHR24396:SF25 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 644 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000024927.2|UniProtKB=F6RWE3 F6RWE3 PTHR10270:SF216 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-17 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110 regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;formation of primary germ layer#GO:0001704;animal gross anatomical part developmental process#GO:0160108;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;angiogenesis#GO:0001525;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of canonical Wnt signaling pathway#GO:0060828;endoderm formation#GO:0001706;embryo development#GO:0009790;negative regulation of signal transduction#GO:0009968;vasculogenesis#GO:0001570;positive regulation of macromolecule metabolic process#GO:0010604;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of macromolecule biosynthetic process#GO:0010556;tube development#GO:0035295;positive regulation of RNA biosynthetic process#GO:1902680;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;tissue development#GO:0009888;negative regulation of Wnt signaling pathway#GO:0030178;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;blood vessel morphogenesis#GO:0048514;gastrulation#GO:0007369;circulatory system development#GO:0072359;cell differentiation#GO:0030154;negative regulation of canonical Wnt signaling pathway#GO:0090090;positive regulation of metabolic process#GO:0009893;heart development#GO:0007507;positive regulation of transcription by RNA polymerase II#GO:0045944;endoderm development#GO:0007492;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000010450.4|UniProtKB=F7F7T9 F7F7T9 PTHR45782:SF4 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;mitochondrial large ribosomal subunit assembly#GO:1902775;ribonucleoprotein complex biogenesis#GO:0022613;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;protein-RNA complex assembly#GO:0022618;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;mitochondrial ribosome assembly#GO:0061668;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000023772.2|UniProtKB=F6SDI4 F6SDI4 FFAR3 PTHR45822:SF6 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 3-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to fatty acid#GO:0070542;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to fatty acid#GO:0071398;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;biological regulation#GO:0065007;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000002810.4|UniProtKB=A0A5F8H447 A0A5F8H447 JAKMIP1 PTHR18935:SF6 GOLGIN SUBFAMILY A MEMBER 4-LIKE ISOFORM X1 JANUS KINASE AND MICROTUBULE-INTERACTING PROTEIN 1 protein binding#GO:0005515;GABA receptor binding#GO:0050811;binding#GO:0005488;signaling receptor binding#GO:0005102 MONDO|Ensembl=ENSMODG00000003633.4|UniProtKB=F7BMD1 F7BMD1 GAS6 PTHR24040:SF14 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN GROWTH ARREST-SPECIFIC PROTEIN 6 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 negative regulation of cellular process#GO:0048523;positive regulation of intracellular signal transduction#GO:1902533;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;signaling#GO:0023052;regulation of cell communication#GO:0010646 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000024759.1|UniProtKB=F7DVS2 F7DVS2 PTHR15258:SF2 FGF BINDING PROTEIN-RELATED FIBROBLAST GROWTH FACTOR-BINDING PROTEIN 1 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000016104.4|UniProtKB=F7EAY7 F7EAY7 FAM13C PTHR15904:SF19 FAM13 PROTEIN FAM13C MONDO|Ensembl=ENSMODG00000025306.1|UniProtKB=A2BDG4 A2BDG4 SPRN PTHR28552:SF1 SHADOW OF PRION PROTEIN SHADOW OF PRION PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000013512.3|UniProtKB=F7D750 F7D750 PTHR23239:SF137 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 10 structural molecule activity#GO:0005198 epithelium development#GO:0060429;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;skin development#GO:0043588;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;animal organ development#GO:0048513;morphogenesis of an epithelium#GO:0002009;epidermis development#GO:0008544;developmental process#GO:0032502;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;intermediate filament organization#GO:0045109 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000024027.2|UniProtKB=F7DNW8 F7DNW8 LOC100012380 PTHR48001:SF128 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008618.4|UniProtKB=F6PH35 F6PH35 RHBDD3 PTHR43066:SF16 RHOMBOID-RELATED PROTEIN RHOMBOID DOMAIN-CONTAINING PROTEIN 3 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000023818.3|UniProtKB=F6QKS9 F6QKS9 CCDC85C PTHR13546:SF14 RE60986P COILED-COIL DOMAIN-CONTAINING PROTEIN 85C anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;apical junction complex#GO:0043296;cell-cell junction#GO:0005911 MONDO|Ensembl=ENSMODG00000009911.3|UniProtKB=F6RU41 F6RU41 EIF2S1 PTHR10602:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 binding#GO:0005488;translation factor activity#GO:0180051;ribonucleoprotein complex binding#GO:0043021;translation initiation factor activity#GO:0003743;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation factor#PC00223;translation initiation factor#PC00224 Apoptosis signaling pathway#P00006>ELF2alpha#P00307 MONDO|Ensembl=ENSMODG00000023326.2|UniProtKB=F6V9P7 F6V9P7 RSPO1 PTHR46987:SF5 NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN R-SPONDIN-1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of canonical Wnt signaling pathway#GO:0060828 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000001619.4|UniProtKB=F7ANI3 F7ANI3 PHKG2 PTHR24347:SF390 SERINE/THREONINE-PROTEIN KINASE PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, LIVER_TESTIS ISOFORM catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein serine/threonine kinase activity#GO:0004674 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;signaling#GO:0023052;carbohydrate metabolic process#GO:0005975;regulation of cellular process#GO:0050794;polysaccharide metabolic process#GO:0005976;response to stimulus#GO:0050896;energy reserve metabolic process#GO:0006112;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 MONDO|Ensembl=ENSMODG00000008897.4|UniProtKB=A0A5F8GFX4 A0A5F8GFX4 PTHR22420:SF2 PROTEIN FAM81A PROTEIN FAM81A MONDO|Ensembl=ENSMODG00000001520.3|UniProtKB=A0A5F8GVL7 A0A5F8GVL7 CEPT1 PTHR10414:SF27 ETHANOLAMINEPHOSPHOTRANSFERASE CHOLINE_ETHANOLAMINEPHOSPHOTRANSFERASE 1 transferase#PC00220 MONDO|Ensembl=ENSMODG00000038629.1|UniProtKB=A0A5F8HL49 A0A5F8HL49 LOC100619741 PTHR48018:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 974 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025593.3|UniProtKB=F6U226 F6U226 PTHR24381:SF472 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020203.3|UniProtKB=A0A5F8H8R8 A0A5F8H8R8 PTHR26452:SF219 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008091.3|UniProtKB=F7GFW3 F7GFW3 SNRPF PTHR11021:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F SMALL NUCLEAR RIBONUCLEOPROTEIN F RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000048605.1|UniProtKB=A0A5F8G5C5 A0A5F8G5C5 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000021318.3|UniProtKB=F7G383 F7G383 SPATA16 PTHR47228:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 16 SPERMATOGENESIS-ASSOCIATED PROTEIN 16 gamete generation#GO:0007276;male gamete generation#GO:0048232;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;spermatogenesis#GO:0007283;developmental process#GO:0032502;sexual reproduction#GO:0019953 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000011403.3|UniProtKB=F6S6I3 F6S6I3 PTHR16675:SF67 MHC CLASS I-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000003710.4|UniProtKB=F7FA38 F7FA38 GRK1 PTHR24355:SF11 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE RHODOPSIN KINASE GRK1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin kinase#P00750 MONDO|Ensembl=ENSMODG00000008416.4|UniProtKB=F7B887 F7B887 CYP2S1 PTHR24300:SF23 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2S1 monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;binding#GO:0005488;tetrapyrrole binding#GO:0046906 cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;response to xenobiotic stimulus#GO:0009410;olefinic compound metabolic process#GO:0120254;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;xenobiotic metabolic process#GO:0006805;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;arachidonate metabolic process#GO:0019369;cellular response to stimulus#GO:0051716;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;response to chemical#GO:0042221;icosanoid metabolic process#GO:0006690;cellular response to xenobiotic stimulus#GO:0071466;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000046744.1|UniProtKB=A0A5F8GD03 A0A5F8GD03 PTHR24302:SF38 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A5 oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395 steroid metabolic process#GO:0008202;metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000013764.4|UniProtKB=A0A5F8GI76 A0A5F8GI76 OBSCN PTHR35971:SF4 SI:DKEY-31G6.6 OBSCURIN kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096 sarcomere#GO:0030017;sarcolemma#GO:0042383;membraneless organelle#GO:0043228;I band#GO:0031674;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;cell periphery#GO:0071944;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;M band#GO:0031430;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;A band#GO:0031672 MONDO|Ensembl=ENSMODG00000012175.3|UniProtKB=F7CY73 F7CY73 IFRD2 PTHR12354:SF8 INTERFERON-RELATED DEVELOPMENTAL REGULATOR INTERFERON-RELATED DEVELOPMENTAL REGULATOR 2 MONDO|Ensembl=ENSMODG00000015720.4|UniProtKB=H9H6S4 H9H6S4 PRKAG1 PTHR13780:SF38 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1 molecular function regulator activity#GO:0098772;nucleotide binding#GO:0000166;cation binding#GO:0043169;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265 positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;cellular response to stress#GO:0033554;regulation of carbohydrate biosynthetic process#GO:0043255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;regulation of carbohydrate metabolic process#GO:0006109;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular response to glucose starvation#GO:0042149;cellular process#GO:0009987;response to nutrient levels#GO:0031667;regulation of primary metabolic process#GO:0080090;response to stress#GO:0006950;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 MONDO|Ensembl=ENSMODG00000013742.5|UniProtKB=K7E4Z4 K7E4Z4 GYS1 PTHR10176:SF2 GLYCOGEN SYNTHASE GLYCOGEN [STARCH] SYNTHASE, MUSCLE catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527 polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;glucan biosynthetic process#GO:0009250;energy reserve metabolic process#GO:0006112;polysaccharide biosynthetic process#GO:0000271;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycogen biosynthetic process#GO:0005978;generation of precursor metabolites and energy#GO:0006091 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Glycogen synthase D#P00709 MONDO|Ensembl=ENSMODG00000025360.2|UniProtKB=F7DKK7 F7DKK7 PTHR11758:SF16 40S RIBOSOMAL PROTEIN S15A SMALL RIBOSOMAL SUBUNIT PROTEIN US8 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000003894.3|UniProtKB=F7D889 F7D889 LAMP1 PTHR11506:SF27 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184 intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000027484.2|UniProtKB=K7E241 K7E241 PTHR10649:SF18 ARYL HYDROCARBON RECEPTOR ARYL HYDROCARBON RECEPTOR 1 BETA transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000007078.3|UniProtKB=F6UEP7 F6UEP7 RPS13 PTHR11885:SF6 RIBOSOMAL PROTEIN S15P/S13E SMALL RIBOSOMAL SUBUNIT PROTEIN US15 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;cytosolic small ribosomal subunit#GO:0022627;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;small-subunit processome#GO:0032040;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000004064.3|UniProtKB=F6VWG6 F6VWG6 TNFRSF11B PTHR23097:SF90 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11B transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010421.4|UniProtKB=F6ZH09 F6ZH09 ITPRID2 PTHR17469:SF11 SPERM SPECIFIC ANTIGEN 2-RELATED PROTEIN ITPRID2 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000004194.4|UniProtKB=F7C573 F7C573 ABCC1 PTHR24223:SF241 ATP-BINDING CASSETTE SUB-FAMILY C MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;oligopeptide transmembrane transporter activity#GO:0035673;tripeptide transmembrane transporter activity#GO:0042937;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;xenobiotic transmembrane transporter activity#GO:0042910;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;carboxylic acid transmembrane transporter activity#GO:0046943 oligopeptide transmembrane transport#GO:0035672;cellular process#GO:0009987;peptide transport#GO:0015833;nitrogen compound transport#GO:0071705;transport#GO:0006810;xenobiotic transport#GO:0042908;oligopeptide transport#GO:0006857;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000038731.1|UniProtKB=A0A5F8G833 A0A5F8G833 PTHR11434:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT ND4L NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4L protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000001077.2|UniProtKB=F7GI03 F7GI03 EPCAM PTHR14168:SF2 TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER EPITHELIAL CELL ADHESION MOLECULE cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;extracellular region#GO:0005576;apical junction complex#GO:0043296 MONDO|Ensembl=ENSMODG00000018101.4|UniProtKB=A0A5F8GHQ0 A0A5F8GHQ0 PTHR21362:SF1 ACROSIN-BINDING PROTEIN ACROSIN-BINDING PROTEIN cellular anatomical entity morphogenesis#GO:0032989;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;male gamete generation#GO:0048232;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;spermatid differentiation#GO:0048515;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;spermatid development#GO:0007286;acrosome assembly#GO:0001675;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;cellular component organization#GO:0016043;germ cell development#GO:0007281;anatomical structure morphogenesis#GO:0009653;gamete generation#GO:0007276;cell differentiation#GO:0030154;reproductive process#GO:0022414;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412 membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503 MONDO|Ensembl=ENSMODG00000019101.3|UniProtKB=F7F9N6 F7F9N6 PTHR11639:SF26 S100 CALCIUM-BINDING PROTEIN CORNULIN metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 endothelial cell migration#GO:0043542;cell motility#GO:0048870;cell migration#GO:0016477;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000001532.4|UniProtKB=F7EMW4 F7EMW4 DYDC1 PTHR23356:SF16 DPY30-RELATED DPY30 DOMAIN-CONTAINING PROTEIN 1 plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;organelle#GO:0043226;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000043912.1|UniProtKB=A0A5F8GYM0 A0A5F8GYM0 DEDD PTHR15205:SF2 DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN cell surface receptor signaling pathway#GO:0007166;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;apoptotic signaling pathway#GO:0097190;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000012367.4|UniProtKB=F7DHM4 F7DHM4 ZNF507 PTHR24388:SF118 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 507 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000021092.4|UniProtKB=F6UIH3 F6UIH3 MAOB PTHR43563:SF24 AMINE OXIDASE AMINE OXIDASE [FLAVIN-CONTAINING] B catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 phenol-containing compound metabolic process#GO:0018958;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;catabolic process#GO:0009056;amine catabolic process#GO:0009310;metabolic process#GO:0008152;serotonin metabolic process#GO:0042428 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;oxidase#PC00175 5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401;Adrenaline and noradrenaline biosynthesis#P00001>MAO#P00067;Dopamine receptor mediated signaling pathway#P05912>MAO#P05963 MONDO|Ensembl=ENSMODG00000015018.4|UniProtKB=F7BXI2 F7BXI2 WHR1 PTHR15243:SF0 SERINE/THREONINE-PROTEIN KINASE 19 WINGED HELIX REPAIR FACTOR 1 DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of cellular response to stress#GO:0080135;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000037872.1|UniProtKB=A0A5F8H7P5 A0A5F8H7P5 PTHR12479:SF5 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 4A regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of membrane permeability#GO:0090559 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;lysosomal membrane#GO:0005765;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000010667.4|UniProtKB=F7CKE3 F7CKE3 DTNA PTHR12268:SF19 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROBREVIN ALPHA membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000016956.4|UniProtKB=F6V5K9 F6V5K9 ELAPOR2 PTHR22727:SF3 PROTEIN CBG13728 ENDOSOME_LYSOSOME-ASSOCIATED APOPTOSIS AND AUTOPHAGY REGULATOR FAMILY MEMBER 2 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of BMP signaling pathway#GO:0030513;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of BMP signaling pathway#GO:0030510;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000016063.4|UniProtKB=F6PL08 F6PL08 ZNF598 PTHR22938:SF0 ZINC FINGER PROTEIN 598 E3 UBIQUITIN-PROTEIN LIGASE ZNF598 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ribonucleoprotein complex binding#GO:0043021;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;protein ubiquitination#GO:0016567;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;gene expression#GO:0010467;translational elongation#GO:0006414;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein modification by small protein conjugation#GO:0032446;rescue of stalled cytosolic ribosome#GO:0072344;cellular component organization#GO:0016043;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein modification by small protein conjugation or removal#GO:0070647;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000016391.4|UniProtKB=F6XR10 F6XR10 TSHZ2 PTHR12487:SF3 TEASHIRT-RELATED TEASHIRT HOMOLOG 2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000000655.4|UniProtKB=F6STR1 F6STR1 CNTNAP4 PTHR15036:SF40 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN-LIKE 4 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental process#GO:0032502;multicellular organism development#GO:0007275 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000038066.1|UniProtKB=A0A5F8GHZ1 A0A5F8GHZ1 VAT1 PTHR44054:SF1 SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE NADPH-DEPENDENT QUINONE OXIDOREDUCTASE VAT1 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;regulation of anatomical structure morphogenesis#GO:0022603;negative regulation of cellular process#GO:0048523 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741 Huntington disease#P00029>PIG3#G01535 MONDO|Ensembl=ENSMODG00000018374.4|UniProtKB=A0A5F8GZG2 A0A5F8GZG2 ZNF148 PTHR24404:SF53 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 148 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000007407.3|UniProtKB=F6YYL0 F6YYL0 CHST15 PTHR15723:SF0 CARBOHYDRATE SULFOTRANSFERASE 15 CARBOHYDRATE SULFOTRANSFERASE 15 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 small molecule biosynthetic process#GO:0044283;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;cellular process#GO:0009987;hexose biosynthetic process#GO:0019319;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate biosynthetic process#GO:0016051;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000019652.4|UniProtKB=A0A5F8HGF5 A0A5F8HGF5 GSN PTHR11977:SF29 VILLIN GELSOLIN small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;actin binding#GO:0003779;actin filament binding#GO:0051015;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092;phosphatidylinositol phosphate binding#GO:1901981 biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament polymerization#GO:0030833;multicellular organismal process#GO:0032501;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin filament depolymerization#GO:0030834;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;system development#GO:0048731;negative regulation of protein-containing complex assembly#GO:0031333;supramolecular fiber organization#GO:0097435;negative regulation of cytoskeleton organization#GO:0051494;anatomical structure development#GO:0048856;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;regulation of actin cytoskeleton organization#GO:0032956;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of anatomical structure size#GO:0090066;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;central nervous system development#GO:0007417;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of actin filament length#GO:0030832;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 FAS signaling pathway#P00020>Gelsolin#P00611 MONDO|Ensembl=ENSMODG00000017196.5|UniProtKB=A0A5F8H5T4 A0A5F8H5T4 JMJD1C PTHR12549:SF6 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN JUMONJI DOMAIN-CONTAINING PROTEIN 1C histone demethylase activity#GO:0032452;chromatin DNA binding#GO:0031490;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;protein demethylase activity#GO:0140457;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;histone modifying activity#GO:0140993;DNA binding#GO:0003677 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000017696.3|UniProtKB=A0A5F8GEB9 A0A5F8GEB9 EIF3J PTHR21681:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 regulation of translational initiation#GO:0006446;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000041721.1|UniProtKB=A0A5F8HI39 A0A5F8HI39 PTHR23304:SF189 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000039241.1|UniProtKB=A0A5F8H8A0 A0A5F8H8A0 monDomV1R1228 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000043564.1|UniProtKB=F6VJW2 F6VJW2 VN2R610 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000167.4|UniProtKB=F6XA66 F6XA66 DNAJC9 PTHR44144:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 9 DNAJ HOMOLOG SUBFAMILY C MEMBER 9 binding#GO:0005488;heat shock protein binding#GO:0031072;protein binding#GO:0005515 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000028154.2|UniProtKB=K7E210 K7E210 PTHR10223:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4 protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;modification-dependent protein binding#GO:0140030 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;proteasome complex#GO:0000502;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 protein modifying enzyme#PC00260;protease#PC00190 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000021334.3|UniProtKB=H9H7X8 H9H7X8 PTHR11267:SF102 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX10 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 MONDO|Ensembl=ENSMODG00000019224.3|UniProtKB=A0A5F8HL64 A0A5F8HL64 KSR1 PTHR23257:SF716 SERINE-THREONINE PROTEIN KINASE KINASE SUPPRESSOR OF RAS 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>KSR-1#P06842 MONDO|Ensembl=ENSMODG00000016674.4|UniProtKB=F7E6L0 F7E6L0 DECR2 PTHR43296:SF12 PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING] oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 reductase#PC00198 MONDO|Ensembl=ENSMODG00000010429.2|UniProtKB=F6ZGV6 F6ZGV6 ABT1 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organelle assembly#GO:0070925;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-RNA complex organization#GO:0071826;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;maturation of 5.8S rRNA#GO:0000460;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000045508.1|UniProtKB=A0A5F8GXU1 A0A5F8GXU1 P2RY13 PTHR24233:SF10 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 13 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000005015.2|UniProtKB=F7ERK0 F7ERK0 SPTLC3 PTHR13693:SF56 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 3 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 ceramide metabolic process#GO:0006672;sphingoid biosynthetic process#GO:0046520;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;ceramide biosynthetic process#GO:0046513;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991 transaminase#PC00216 MONDO|Ensembl=ENSMODG00000008745.4|UniProtKB=F6PSP0 F6PSP0 SIPA1L2 PTHR15711:SF7 RAP GTPASE-ACTIVATING PROTEIN SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE PROTEIN 2 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 G-protein modulator#PC00022;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000014396.5|UniProtKB=F6SRI1 F6SRI1 KRT32 PTHR23239:SF155 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA2 structural molecule activity#GO:0005198 developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;morphogenesis of an epithelium#GO:0002009;organelle organization#GO:0006996;cellular process#GO:0009987;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;cytoskeleton organization#GO:0007010;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000023861.3|UniProtKB=A0A5F8GHE6 A0A5F8GHE6 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000001823.3|UniProtKB=F6T5G5 F6T5G5 ARPP19 PTHR10358:SF4 ENDOSULFINE CAMP-REGULATED PHOSPHOPROTEIN 19 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000014808.4|UniProtKB=F7EKK6 F7EKK6 SCPEP1 PTHR11802:SF3 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE RETINOID-INDUCIBLE SERINE CARBOXYPEPTIDASE carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000015138.4|UniProtKB=F7CZL2 F7CZL2 SLC44A4 PTHR12385:SF37 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 4 organophosphate ester transmembrane transporter activity#GO:0015605;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;quaternary ammonium group transmembrane transporter activity#GO:0015651 vitamin transport#GO:0051180;organophosphate ester transport#GO:0015748;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000003817.3|UniProtKB=F6YW40 F6YW40 LOC100019894 PTHR26453:SF29 OLFACTORY RECEPTOR OLFACTORY RECEPTOR MOR277-1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002702.2|UniProtKB=F7CY30 F7CY30 DYNLRB1 PTHR10779:SF17 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 1 protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;dynein complex#GO:0030286;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000044275.1|UniProtKB=A0A5F8G3T9 A0A5F8G3T9 LOC100031177 PTHR26454:SF77 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007397.4|UniProtKB=F6YZ60 F6YZ60 P4HA3 PTHR10869:SF223 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-3 dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000049107.1|UniProtKB=A0A5F8HKG3 A0A5F8HKG3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000028822.2|UniProtKB=F6X704 F6X704 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000014557.3|UniProtKB=A0A5F8H247 A0A5F8H247 COLQ PTHR24023:SF861 COLLAGEN ALPHA ACETYLCHOLINESTERASE COLLAGENIC TAIL PEPTIDE structural molecule activity#GO:0005198;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;heparin binding#GO:0008201;extracellular matrix structural constituent#GO:0005201 cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000014746.4|UniProtKB=A0A5F8G6Y9 A0A5F8G6Y9 GRIA4 PTHR18966:SF100 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 4 gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;molecular transducer activity#GO:0060089;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310 chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267 membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;neuron projection#GO:0043005;protein-containing complex#GO:0032991;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351;postsynapse#GO:0098794;dendritic spine#GO:0043197;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;neuron spine#GO:0044309;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu4#P01015;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019 MONDO|Ensembl=ENSMODG00000019519.4|UniProtKB=F7AF12 F7AF12 ARPIN PTHR31199:SF1 ARPIN ARPIN negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;negative regulation of cytoskeleton organization#GO:0051494;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament organization#GO:0110053;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523 MONDO|Ensembl=ENSMODG00000000050.3|UniProtKB=F6REI1 F6REI1 BPIFB3 PTHR46019:SF5 BPI FOLD-CONTAINING FAMILY B MEMBER 4-RELATED BPI FOLD-CONTAINING FAMILY B MEMBER 3 MONDO|Ensembl=ENSMODG00000008712.4|UniProtKB=F6PVX8 F6PVX8 TOX PTHR45781:SF4 AGAP000281-PA THYMOCYTE SELECTION-ASSOCIATED HIGH MOBILITY GROUP BOX PROTEIN TOX nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;DNA binding#GO:0003677 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell development#GO:0048468;leukocyte differentiation#GO:0002521;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;hemopoiesis#GO:0030097;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000019284.4|UniProtKB=F6SHA5 F6SHA5 PAM PTHR10680:SF14 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 MONDO|Ensembl=ENSMODG00000010243.4|UniProtKB=F6W6P3 F6W6P3 RAMP3 PTHR14076:SF2 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RECEPTOR ACTIVITY-MODIFYING PROTEIN 3 coreceptor activity#GO:0015026;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 protein transport#GO:0015031;monoatomic ion transport#GO:0006811;cellular localization#GO:0051641;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;endocytosis#GO:0006897;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657;response to endogenous stimulus#GO:0009719;calcium ion transport#GO:0006816;import into cell#GO:0098657;protein localization to cell periphery#GO:1990778;vesicle-mediated transport#GO:0016192;response to chemical#GO:0042221;cellular process#GO:0009987;establishment of protein localization#GO:0045184;signal transduction#GO:0007165;response to hormone#GO:0009725;receptor internalization#GO:0031623;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;localization within membrane#GO:0051668;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;protein localization to plasma membrane#GO:0072659;intracellular protein localization#GO:0008104;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;macromolecule localization#GO:0033036 signaling receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000046721.1|UniProtKB=A0A5F8GWJ8 A0A5F8GWJ8 LOC100009776 PTHR10579:SF52 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000016463.4|UniProtKB=H9H6V2 H9H6V2 PTHR22978:SF40 B-CELL TRANSLOCATION GENE ANTI-PROLIFERATIVE PROTEIN DOMAIN-CONTAINING PROTEIN biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;negative regulation of cell population proliferation#GO:0008285;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000037321.1|UniProtKB=A0A5F8G8U0 A0A5F8G8U0 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000038613.1|UniProtKB=A0A5F8GHW2 A0A5F8GHW2 PTHR40376:SF1 ODONTOGENESIS ASSOCIATED PHOSPHOPROTEIN ODONTOGENESIS ASSOCIATED PHOSPHOPROTEIN biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of developmental process#GO:0051094;regulation of multicellular organismal development#GO:2000026 MONDO|Ensembl=ENSMODG00000014270.4|UniProtKB=F6WJJ0 F6WJJ0 HYDIN PTHR23053:SF0 DLEC1 DELETED IN LUNG AND ESOPHAGEAL CANCER 1 AXONEMAL CENTRAL PAIR APPARATUS PROTEIN HYDIN microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;cilium movement#GO:0003341;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;axoneme#GO:0005930;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000019213.3|UniProtKB=H9H7A8 H9H7A8 LOC100028412 PTHR19918:SF1 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED FIZZY-RELATED PROTEIN HOMOLOG enzyme regulator activity#GO:0030234;protein-containing complex binding#GO:0044877;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;binding#GO:0005488;enzyme activator activity#GO:0008047 positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;modification-dependent protein catabolic process#GO:0019941;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;primary metabolic process#GO:0044238;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;proteasomal protein catabolic process#GO:0010498;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893 intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000046790.1|UniProtKB=A0A5F8HB48 A0A5F8HB48 LOC100031181 PTHR24249:SF271 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 6 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000024043.1|UniProtKB=F6ZCD8 F6ZCD8 LOC100022596 PTHR13007:SF19 PRE-MRNA SPLICING FACTOR-RELATED PRE-MRNA-SPLICING FACTOR 18 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000020458.3|UniProtKB=F7FJJ6 F7FJJ6 BBS10 PTHR14667:SF2 BARDET-BIEDL SYNDROME 10 PROTEIN BBSOME COMPLEX ASSEMBLY PROTEIN BBS10 chaperone-mediated protein complex assembly#GO:0051131;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607 MONDO|Ensembl=ENSMODG00000028964.2|UniProtKB=K7E3P9 K7E3P9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012623.4|UniProtKB=F6S2A0 F6S2A0 PIP4K2B PTHR23086:SF22 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 kinase#PC00137;transferase#PC00220 MONDO|Ensembl=ENSMODG00000002339.4|UniProtKB=A0A5F8HBR5 A0A5F8HBR5 ZNF746 PTHR23232:SF175 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER FAMILY MEMBER 767-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000037906.1|UniProtKB=A0A5F8G805 A0A5F8G805 PTHR48002:SF99 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002568.4|UniProtKB=F7F6C6 F7F6C6 PYCARD PTHR46985:SF2 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;molecular function activator activity#GO:0140677;pattern recognition receptor activity#GO:0038187;enzyme regulator activity#GO:0030234;molecular transducer activity#GO:0060089;peptidase activator activity#GO:0016504;enzyme activator activity#GO:0008047;signaling receptor activity#GO:0038023;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;inflammatory response#GO:0006954;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;apoptotic signaling pathway#GO:0097190;regulation of innate immune response#GO:0045088;defense response#GO:0006952;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;intrinsic apoptotic signaling pathway#GO:0097193;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518 intracellular organelle#GO:0043229;canonical inflammasome complex#GO:0061702;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000025071.2|UniProtKB=F6RR47 F6RR47 PTHR43128:SF10 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A CHAIN catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 monocarboxylic acid catabolic process#GO:0072329;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;generation of precursor metabolites and energy#GO:0006091 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000017888.4|UniProtKB=A0A5F8G2Y3 A0A5F8G2Y3 AGO4 PTHR22891:SF26 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-4 RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;single-stranded RNA binding#GO:0003727;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;RNA biosynthetic process#GO:0032774;post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;RNA metabolic process#GO:0016070;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000012897.3|UniProtKB=A0A5F8H5K4 A0A5F8H5K4 PTHR10030:SF45 ALPHA-L-FUCOSIDASE PLASMA ALPHA-L-FUCOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 glycosidase#PC00110;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000011066.3|UniProtKB=F7EMA5 F7EMA5 MECR PTHR43981:SF9 ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL small molecule metabolic process#GO:0044281;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 reductase#PC00198;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000001785.5|UniProtKB=A0A5F8GBI2 A0A5F8GBI2 TNRC6C PTHR13020:SF9 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6C PROTEIN positive regulation of metabolic process#GO:0009893;negative regulation of metabolic process#GO:0009892;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;miRNA-mediated post-transcriptional gene silencing#GO:0035195;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;regulation of RNA metabolic process#GO:0051252;post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of mRNA catabolic process#GO:0061014;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000007138.4|UniProtKB=A0A5F8HFD2 A0A5F8HFD2 PLEKHA7 PTHR12752:SF4 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 7 cell adhesion#GO:0007155;cell-cell junction organization#GO:0045216;protein-containing complex organization#GO:0043933;cell-cell junction maintenance#GO:0045217;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;adherens junction organization#GO:0034332;cellular component biogenesis#GO:0044085;cell junction organization#GO:0034330;cellular component assembly#GO:0022607 apical junction complex#GO:0043296;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell junction#GO:0030054;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000012300.4|UniProtKB=A0A5F8H019 A0A5F8H019 LARP1B PTHR22792:SF50 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 1B RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000011289.4|UniProtKB=F6WZE5 F6WZE5 SZT2 PTHR14918:SF3 KICSTOR COMPLEX PROTEIN SZT2 KICSTOR COMPLEX PROTEIN SZT2 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;nervous system development#GO:0007399;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;regulation of TOR signaling#GO:0032006;response to nutrient levels#GO:0031667;regulation of TORC1 signaling#GO:1903432;multicellular organism development#GO:0007275;developmental process#GO:0032502;negative regulation of TORC1 signaling#GO:1904262;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;central nervous system development#GO:0007417;negative regulation of TOR signaling#GO:0032007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;system development#GO:0048731;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;anatomical structure development#GO:0048856;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;peroxisome#GO:0005777;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;microbody#GO:0042579;lysosomal membrane#GO:0005765;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000044249.1|UniProtKB=A0A5F8H0K6 A0A5F8H0K6 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000018400.4|UniProtKB=F6QAA0 F6QAA0 IBTK PTHR22872:SF15 BTK-BINDING PROTEIN-RELATED INHIBITOR OF BRUTON TYROSINE KINASE kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;calcium ion transmembrane transport#GO:0070588;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000044362.1|UniProtKB=A0A5F8G6T8 A0A5F8G6T8 MAL PTHR22776:SF12 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MYELIN AND LYMPHOCYTE PROTEIN structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;protein insertion into membrane#GO:0051205;nervous system development#GO:0007399;membrane organization#GO:0061024;biological regulation#GO:0065007;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;myelination#GO:0042552;intracellular protein localization#GO:0008104;developmental process#GO:0032502;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular localization#GO:0051641;anatomical structure development#GO:0048856;localization#GO:0051179;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;localization within membrane#GO:0051668 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;membrane raft#GO:0045121;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;membrane microdomain#GO:0098857;apical part of cell#GO:0045177 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017061.2|UniProtKB=F6XHT7 F6XHT7 PTHR26452:SF247 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5K3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004931.4|UniProtKB=F7BG77 F7BG77 SLC22A15 PTHR24064:SF170 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 15 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000016916.4|UniProtKB=F6VN95 F6VN95 FRMD4A PTHR46079:SF3 FERM DOMAIN-CONTAINING PROTEIN 4 FERM DOMAIN-CONTAINING PROTEIN 4A apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;adherens junction#GO:0005912;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000024949.2|UniProtKB=F6U304 F6U304 PTHR12962:SF3 CALCIUM-REGULATED HEAT STABLE PROTEIN CRHSP-24-RELATED CALCIUM-REGULATED HEAT-STABLE PROTEIN 1 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of mRNA stability#GO:0043488;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000029765.2|UniProtKB=K7E674 K7E674 PTHR14789:SF4 CHONDROLECTIN VARIANT CHODLFDELTAE. ENDOSIALIN binding#GO:0005488;protein binding#GO:0005515;extracellular matrix binding#GO:0050840 cellular process#GO:0009987;cell migration#GO:0016477;cell motility#GO:0048870 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000010182.5|UniProtKB=A0A5F8H7D9 A0A5F8H7D9 RBM27 PTHR14398:SF1 RNA RECOGNITION RRM/RNP DOMAIN RNA-BINDING PROTEIN 27 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000009655.4|UniProtKB=F6QSA2 F6QSA2 DMC1 PTHR22942:SF30 RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER MEIOTIC RECOMBINATION PROTEIN DMC1 HOMOLOG ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097 cellular component organization#GO:0016043;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;protein-containing complex assembly#GO:0065003;response to stimulus#GO:0050896;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;double-strand break repair#GO:0006302;protein-containing complex organization#GO:0043933;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;reproductive process#GO:0022414;homologous recombination#GO:0035825;mitotic recombination#GO:0006312;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;DNA damage response#GO:0006974;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000050337.1|UniProtKB=A0A5F8H450 A0A5F8H450 PTHR47614:SF4 GLYCOPHORIN-C NEUREXIN_SYNDECAN_GLYCOPHORIN C DOMAIN-CONTAINING PROTEIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane#GO:0016020;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000020323.4|UniProtKB=A0A5F8G948 A0A5F8G948 MS4A5 PTHR23320:SF54 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 5 transporter#PC00227 MONDO|Ensembl=ENSMODG00000016421.4|UniProtKB=F7ASV4 F7ASV4 DKK1 PTHR12113:SF11 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 1 protein binding#GO:0005515;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;signaling receptor inhibitor activity#GO:0030547;signaling receptor regulator activity#GO:0030545;binding#GO:0005488 regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000009254.4|UniProtKB=F7DVV1 F7DVV1 GPR157 PTHR23112:SF47 G PROTEIN-COUPLED RECEPTOR 157-RELATED G PROTEIN-COUPLED RECEPTOR 157 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000019234.1|UniProtKB=F6RDY8 F6RDY8 LOC100024823 PTHR33505:SF4 ZGC:162634 PROTEIN PREY, MITOCHONDRIAL MONDO|Ensembl=ENSMODG00000021467.4|UniProtKB=F7GDJ5 F7GDJ5 EMILIN2 PTHR15427:SF5 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMILIN-2 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of biological process#GO:0048518;regulation of response to wounding#GO:1903034;positive regulation of cell-cell adhesion#GO:0022409;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;regulation of platelet aggregation#GO:0090330;positive regulation of coagulation#GO:0050820;regulation of biological quality#GO:0065008;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;positive regulation of angiogenesis#GO:0045766;regulation of wound healing#GO:0061041;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;regulation of response to stimulus#GO:0048583;positive regulation of developmental process#GO:0051094;regulation of vasculature development#GO:1901342;regulation of response to stress#GO:0080134;regulation of hemostasis#GO:1900046;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;regulation of coagulation#GO:0050818;positive regulation of response to stimulus#GO:0048584;regulation of platelet activation#GO:0010543;regulation of angiogenesis#GO:0045765;positive regulation of cell adhesion#GO:0045785;regulation of developmental process#GO:0050793;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794 supramolecular fiber#GO:0099512;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;interstitial matrix#GO:0005614;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;protein complex involved in cell adhesion#GO:0098636 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007341.3|UniProtKB=F7B0G5 F7B0G5 LOC100029307 PTHR24242:SF197 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000007914.4|UniProtKB=A0A5F8G9A3 A0A5F8G9A3 RAC1 PTHR24072:SF395 RHO FAMILY GTPASE RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein kinase binding#GO:0019901;protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;intracellular signaling cassette#GO:0141124;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;cell projection assembly#GO:0030031;neuron development#GO:0048666;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;cell morphogenesis#GO:0000902;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell development#GO:0048468;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;neurogenesis#GO:0022008;actin filament organization#GO:0007015;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;axon guidance#GO:0007411;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;Rac protein signal transduction#GO:0016601;establishment or maintenance of cell polarity#GO:0007163;generation of neurons#GO:0048699;cell projection organization#GO:0030030;cell differentiation#GO:0030154;signaling#GO:0023052;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;cellular developmental process#GO:0048869;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;regulation of cell motility#GO:2000145;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;supramolecular fiber organization#GO:0097435;system development#GO:0048731;cortical cytoskeleton organization#GO:0030865;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;regulation of developmental process#GO:0050793 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886 G-protein#PC00020;small GTPase#PC00208 CCKR signaling map#P06959>RAC1-GTP#P07214;Huntington disease#P00029>Rac#P00775;EGF receptor signaling pathway#P00018>Rac#P00564;Ras Pathway#P04393>Rac#P04559;Axon guidance mediated by semaphorins#P00007>Rac#P00340;VEGF signaling pathway#P00056>Rac#P01421;CCKR signaling map#P06959>RAC1-GDP#P07225;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Integrin signalling pathway#P00034>Rac#P00927;T cell activation#P00053>rac#P01324;Gonadotropin-releasing hormone receptor pathway#P06664>Rac1#P06860;FGF signaling pathway#P00021>Rac#P00645;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rac#P00872;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;Axon guidance mediated by netrin#P00009>Rac#P00366;p38 MAPK pathway#P05918>Rac#P06021;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;B cell activation#P00010>Rac#P00385 MONDO|Ensembl=ENSMODG00000000109.4|UniProtKB=F6YC42 F6YC42 TBC1D19 PTHR16110:SF1 TBC1 DOMAIN FAMILY MEMBER 19 TBC1 DOMAIN FAMILY MEMBER 19 MONDO|Ensembl=ENSMODG00000009443.2|UniProtKB=A0A5F8GAM9 A0A5F8GAM9 SLC39A14 PTHR12191:SF5 SOLUTE CARRIER FAMILY 39 METAL CATION SYMPORTER ZIP14 secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;bicarbonate transmembrane transporter activity#GO:0015106;zinc ion transmembrane transporter activity#GO:0005385;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;import across plasma membrane#GO:0098739;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;import into cell#GO:0098657;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000014183.3|UniProtKB=F6U6S6 F6U6S6 CLDN25 PTHR12002:SF87 CLAUDIN CLAUDIN-25 cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216 apical junction complex#GO:0043296;anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000016662.4|UniProtKB=F7G717 F7G717 PDIA2 PTHR18929:SF93 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A2 protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;intramolecular oxidoreductase activity#GO:0016860 protein maturation#GO:0051604;gene expression#GO:0010467;response to stimulus#GO:0050896;protein folding#GO:0006457;biosynthetic process#GO:0009058;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;cellular response to stress#GO:0033554 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000011456.4|UniProtKB=F6W0X5 F6W0X5 KLHDC1 PTHR46228:SF1 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000023510.3|UniProtKB=A0A5F8GYC9 A0A5F8GYC9 TTLL9 PTHR12241:SF39 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL9-RELATED binding#GO:0005488;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000008986.4|UniProtKB=F7BQD7 F7BQD7 ZDHHC13 PTHR24161:SF16 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PALMITOYLTRANSFERASE ZDHHC13 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000000684.4|UniProtKB=F6WM83 F6WM83 SYT2 PTHR10024:SF223 SYNAPTOTAGMIN SYNAPTOTAGMIN-2 protein binding#GO:0005515;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;molecular sensor activity#GO:0140299;SNARE binding#GO:0000149;binding#GO:0005488;phospholipid binding#GO:0005543 regulation of exocytosis#GO:0017157;secretion#GO:0046903;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;regulation of neurotransmitter transport#GO:0051588;regulation of synaptic vesicle exocytosis#GO:2000300;export from cell#GO:0140352;signaling#GO:0023052;regulation of neurotransmitter secretion#GO:0046928;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;exocytosis#GO:0006887;regulation of localization#GO:0032879;regulation of transport#GO:0051049;positive regulation of vesicle fusion#GO:0031340;vesicle-mediated transport in synapse#GO:0099003;regulated exocytosis#GO:0045055;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic vesicle exocytosis#GO:0016079;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536 organelle membrane#GO:0031090;plasma membrane#GO:0005886;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;axon#GO:0030424;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;neuron projection#GO:0043005;presynapse#GO:0098793;secretory vesicle#GO:0099503;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular vesicle#GO:0097708 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 MONDO|Ensembl=ENSMODG00000007566.4|UniProtKB=A0A5F8G4C4 A0A5F8G4C4 STK39 PTHR48012:SF14 STERILE20-LIKE KINASE, ISOFORM B-RELATED STE20_SPS1-RELATED PROLINE-ALANINE-RICH PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;response to osmotic stress#GO:0006970;regulation of cell migration#GO:0030334;positive regulation of locomotion#GO:0040017;cellular response to stimulus#GO:0051716;hyperosmotic response#GO:0006972;cellular response to environmental stimulus#GO:0104004;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of leukocyte migration#GO:0002685;cellular response to osmotic stress#GO:0071470;regulation of lymphocyte migration#GO:2000401;intracellular signal transduction#GO:0035556;positive regulation of chemotaxis#GO:0050921;regulation of cell motility#GO:2000145;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;regulation of response to external stimulus#GO:0032101;response to chemical#GO:0042221;cellular response to abiotic stimulus#GO:0071214;positive regulation of response to external stimulus#GO:0032103;cellular response to chemical stress#GO:0062197;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;positive regulation of cell motility#GO:2000147;regulation of chemotaxis#GO:0050920;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000036580.1|UniProtKB=A0A5F8GIB0 A0A5F8GIB0 IKZF4 PTHR24404:SF28 ZINC FINGER PROTEIN ZINC FINGER PROTEIN EOS sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000025740.2|UniProtKB=F6T1Y6 F6T1Y6 ATP5MJ PTHR15233:SF1 MITOCHONDRIAL PROTEOLIPID ATP SYNTHASE F(0) COMPLEX SUBUNIT J, MITOCHONDRIAL proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;proton-transporting ATP synthase complex#GO:0045259 MONDO|Ensembl=ENSMODG00000047456.1|UniProtKB=A0A5F8GD39 A0A5F8GD39 CLDN1 PTHR12002:SF92 CLAUDIN CLAUDIN-1 protein binding#GO:0005515;virus receptor activity#GO:0001618;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell adhesion#GO:0007155;cell-cell junction organization#GO:0045216;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000010423.4|UniProtKB=A0A5F8HCY0 A0A5F8HCY0 ATG16L1 PTHR19878:SF6 AUTOPHAGY PROTEIN 16-LIKE AUTOPHAGY-RELATED PROTEIN 16-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component assembly#GO:0022607;catabolic process#GO:0009056;macroautophagy#GO:0016236;metabolic process#GO:0008152;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;autophagosome assembly#GO:0000045 vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;autophagosome#GO:0005776;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000007330.4|UniProtKB=F7EF83 F7EF83 FSBP PTHR15386:SF0 FIBRINOGEN SILENCER-BINDING PROTEIN FIBRINOGEN SILENCER-BINDING PROTEIN membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000006905.3|UniProtKB=F6PTZ2 F6PTZ2 TK2 PTHR10513:SF24 DEOXYNUCLEOSIDE KINASE THYMIDINE KINASE 2, MITOCHONDRIAL deoxynucleoside kinase activity#GO:0019136;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000018911.5|UniProtKB=A0A5F8G5E3 A0A5F8G5E3 RORC PTHR45805:SF1 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR ROR-GAMMA RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;steroid binding#GO:0005496;sterol binding#GO:0032934;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;lipid binding#GO:0008289;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169 Hypoxia response via HIF activation#P00030>TOR#P00817 MONDO|Ensembl=ENSMODG00000020402.4|UniProtKB=F7BKH5 F7BKH5 RXFP3 PTHR24230:SF168 G-PROTEIN COUPLED RECEPTOR RELAXIN-3 RECEPTOR 1 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000008334.4|UniProtKB=F7F2P2 F7F2P2 SLC28A3 PTHR10590:SF26 SODIUM/NUCLEOSIDE COTRANSPORTER SOLUTE CARRIER FAMILY 28 MEMBER 3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;nucleobase transmembrane transporter activity#GO:0015205;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;nucleoside transmembrane transporter activity#GO:0005337;solute:monoatomic cation symporter activity#GO:0015294;symporter activity#GO:0015293;carbohydrate derivative transmembrane transporter activity#GO:1901505;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;nucleobase-containing compound transmembrane transporter activity#GO:0015932 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000002917.3|UniProtKB=A0A5F8GN90 A0A5F8GN90 NAA25 PTHR22767:SF3 N-TERMINAL ACETYLTRANSFERASE-RELATED N-ALPHA-ACETYLTRANSFERASE 25, NATB AUXILIARY SUBUNIT molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000007805.2|UniProtKB=F6ZIN8 F6ZIN8 LOC100619212 PTHR48002:SF115 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K14 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011100.4|UniProtKB=F7DL38 F7DL38 LRRC24 PTHR24373:SF269 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 24 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002522.3|UniProtKB=F7B8X8 F7B8X8 SLC18A3 PTHR23506:SF13 GH10249P VESICULAR ACETYLCHOLINE TRANSPORTER monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoamine transmembrane transporter activity#GO:0008504;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297 synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular process#GO:0009987;anterograde trans-synaptic signaling#GO:0098916;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 distal axon#GO:0150034;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;neuron projection terminus#GO:0044306;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;membrane coat#GO:0030117;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;trans-Golgi network transport vesicle#GO:0030140;axon#GO:0030424;AP-1 adaptor complex#GO:0030121;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;axon terminus#GO:0043679;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;cell projection#GO:0042995;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;coated membrane#GO:0048475;coated vesicle#GO:0030135;endocytic vesicle#GO:0030139;intracellular organelle#GO:0043229;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vesicle coat#GO:0030120;presynapse#GO:0098793;neuron projection#GO:0043005;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle membrane#GO:0030665;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin vesicle coat#GO:0030125 secondary carrier transporter#PC00258;transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>VAChT#P01065;Nicotinic acetylcholine receptor signaling pathway#P00044>VAChT#P01089;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>VAChT#P01078 MONDO|Ensembl=ENSMODG00000049635.1|UniProtKB=A0A5F8GTC1 A0A5F8GTC1 MFAP3 PTHR14340:SF4 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 MONDO|Ensembl=ENSMODG00000002687.3|UniProtKB=F7CYM7 F7CYM7 DUT PTHR11241:SF0 DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside triphosphate diphosphatase activity#GO:0047429;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;cation binding#GO:0043169;magnesium ion binding#GO:0000287 nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;organophosphate biosynthetic process#GO:0090407;nucleoside monophosphate biosynthetic process#GO:0009124;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;nucleobase-containing compound biosynthetic process#GO:0034654 phosphatase#PC00181;hydrolase#PC00121 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUTP pyrophosphatase#P02918 MONDO|Ensembl=ENSMODG00000020559.3|UniProtKB=A0A5F8HLU7 A0A5F8HLU7 N4BP2 PTHR46535:SF1 NEDD4-BINDING PROTEIN 2 NEDD4-BINDING PROTEIN 2 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;endonuclease activity#GO:0004519 MONDO|Ensembl=ENSMODG00000024329.2|UniProtKB=Q2AB87 Q2AB87 TAS2R40 PTHR11394:SF47 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 40 transmembrane signaling receptor activity#GO:0004888;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023 system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002003.4|UniProtKB=F6RHG5 F6RHG5 ATXN7L2 PTHR15117:SF5 ATAXIN 7 RELATED ATAXIN-7-LIKE PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 MONDO|Ensembl=ENSMODG00000012628.3|UniProtKB=F6WUF2 F6WUF2 CEL PTHR43903:SF1 NEUROLIGIN BILE SALT-ACTIVATED LIPASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;signaling receptor activity#GO:0038023;signaling receptor binding#GO:0005102;lipase activity#GO:0016298;binding#GO:0005488;triacylglycerol lipase activity#GO:0004806;carboxylic ester hydrolase activity#GO:0052689;molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;lipid catabolic process#GO:0016042;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;cellular component assembly#GO:0022607;nervous system development#GO:0007399;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789;membrane assembly#GO:0071709;synapse assembly#GO:0007416;endocytosis#GO:0006897;regulation of body fluid levels#GO:0050878;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;cell adhesion#GO:0007155;cellular localization#GO:0051641;ceramide metabolic process#GO:0006672;regulation of biological quality#GO:0065008;synaptic vesicle recycling#GO:0036465;multicellular organismal process#GO:0032501;digestion#GO:0007586;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;biological regulation#GO:0065007;lipid metabolic process#GO:0006629;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;system process#GO:0003008;chemical synaptic transmission#GO:0007268;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;synaptic vesicle endocytosis#GO:0048488;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;postsynapse organization#GO:0099173;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;anatomical structure development#GO:0048856;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;system development#GO:0048731 cell surface#GO:0009986;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000004878.5|UniProtKB=F7CKN7 F7CKN7 SLC39A3 PTHR11040:SF221 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP3 monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000003046.4|UniProtKB=F6PP60 F6PP60 MFAP3L PTHR14340:SF2 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 MICROFIBRILLAR-ASSOCIATED PROTEIN 3-LIKE MONDO|Ensembl=ENSMODG00000000820.4|UniProtKB=F6S9C3 F6S9C3 MFSD14B PTHR23504:SF32 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 SOLUTE CARRIER FAMILY 71 MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000017089.4|UniProtKB=F6V427 F6V427 MTX1 PTHR12289:SF34 METAXIN RELATED METAXIN-1 cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;protein insertion into mitochondrial outer membrane#GO:0045040;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;cellular component biogenesis#GO:0044085;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;protein insertion into membrane#GO:0051205;cellular component assembly#GO:0022607;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933 mitochondrial outer membrane translocase complex#GO:0005742;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 MONDO|Ensembl=ENSMODG00000014191.3|UniProtKB=F6TRF6 F6TRF6 PFDN6 PTHR21431:SF0 PREFOLDIN SUBUNIT 6 PREFOLDIN SUBUNIT 6 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000003413.5|UniProtKB=F7GKV2 F7GKV2 DDX54 PTHR24031:SF292 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX54 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000004605.4|UniProtKB=F6Y4H2 F6Y4H2 GRM7 PTHR24060:SF98 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 7 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;glutamate receptor activity#GO:0008066;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;glutamate receptor signaling pathway#GO:0007215;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 MONDO|Ensembl=ENSMODG00000012109.5|UniProtKB=F6WRU4 F6WRU4 MED13L PTHR48249:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13-LIKE transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000025378.3|UniProtKB=F6ZAC3 F6ZAC3 TRABD2B PTHR31120:SF8 METALLOPROTEASE TIKI METALLOPROTEASE TIKI2 Wnt-protein binding#GO:0017147;protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;negative regulation of Wnt signaling pathway#GO:0030178;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle membrane#GO:0031090;plasma membrane#GO:0005886;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000027579.2|UniProtKB=K7DYX0 K7DYX0 UPRT PTHR10285:SF171 URIDINE KINASE URACIL PHOSPHORIBOSYLTRANSFERASE HOMOLOG intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172;kinase#PC00137 Salvage pyrimidine ribonucleotides#P02775>Uracil phosphoribosyl transferase#P03151 MONDO|Ensembl=ENSMODG00000044751.1|UniProtKB=A0A5F8HFL9 A0A5F8HFL9 PTHR14947:SF26 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 781 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000019241.4|UniProtKB=F6QTI3 F6QTI3 PPM1K PTHR47992:SF274 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE MN(2+)-DEPENDENT 1K phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000003969.4|UniProtKB=F7FMF5 F7FMF5 GFPT2 PTHR10937:SF10 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING GLUTAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 UDP-N-acetylglucosamine metabolic process#GO:0006047;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine biosynthetic process#GO:0006048;nucleoside phosphate metabolic process#GO:0006753;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleotide-sugar metabolic process#GO:0009225;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637 transaminase#PC00216 N-acetylglucosamine metabolism#P02756>Fructose-6-phosphate aminotransferase#P03042;O-antigen biosynthesis#P02757>Fructose-6-phosphate aminotransferase#P03051 MONDO|Ensembl=ENSMODG00000040274.1|UniProtKB=A0A5F8G880 A0A5F8G880 GOLT1B PTHR21493:SF79 CGI-141-RELATED/LIPASE CONTAINING PROTEIN VESICLE TRANSPORT PROTEIN GOT1B membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000040998.1|UniProtKB=F6WNY8 F6WNY8 LOC100017550 PTHR21297:SF0 DNA-DIRECTED RNA POLYMERASE II DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 protein binding#GO:0005515;translation initiation factor binding#GO:0031369;binding#GO:0005488 RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 MONDO|Ensembl=ENSMODG00000041811.1|UniProtKB=K7E4Y5 K7E4Y5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000040637.1|UniProtKB=A0A5F8GP18 A0A5F8GP18 PTHR15439:SF0 RETINOBLASTOMA-BINDING PROTEIN 6 E3 UBIQUITIN-PROTEIN LIGASE RBBP6 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000004340.4|UniProtKB=F6X5W9 F6X5W9 RACGAP1 PTHR46199:SF3 RAC GTPASE-ACTIVATING PROTEIN 1 RAC GTPASE-ACTIVATING PROTEIN 1 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 nuclear division#GO:0000280;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;Rho protein signal transduction#GO:0007266;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;signaling#GO:0023052;response to stimulus#GO:0050896;mitotic spindle organization#GO:0007052;chromosome segregation#GO:0007059;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;intracellular signaling cassette#GO:0141124;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;cell division#GO:0051301;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;regulation of cellular process#GO:0050794;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;spindle organization#GO:0007051;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264 membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;nucleus#GO:0005634;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;spindle#GO:0005819;membraneless organelle#GO:0043228;cleavage furrow#GO:0032154;intracellular protein-containing complex#GO:0140535;midbody#GO:0030496;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;membrane-bounded organelle#GO:0043227 G-protein modulator#PC00022;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000042556.1|UniProtKB=A0A5F8H0W3 A0A5F8H0W3 ORMDL1 PTHR12665:SF12 ORMDL PROTEINS ORM1-LIKE PROTEIN 1 cellular process#GO:0009987;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;ceramide metabolic process#GO:0006672 protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000009563.4|UniProtKB=F7BJG3 F7BJG3 RERE PTHR13859:SF12 ATROPHIN-RELATED ARGININE-GLUTAMIC ACID DIPEPTIDE REPEATS PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000029317.2|UniProtKB=A0A5F8GMP2 A0A5F8GMP2 FSIP1 PTHR22012:SF2 FIBROUS SHEATH INTERACTING PROTEIN 1 FIBROUS SHEATH-INTERACTING PROTEIN 1 MONDO|Ensembl=ENSMODG00000010484.3|UniProtKB=F7ESJ0 F7ESJ0 SFRP1 PTHR11309:SF87 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 1 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;signaling receptor activity#GO:0038023 cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;non-canonical Wnt signaling pathway#GO:0035567;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>sFRP#P01434;Angiogenesis#P00005>FRP#P00237 MONDO|Ensembl=ENSMODG00000016875.4|UniProtKB=F6Y1G6 F6Y1G6 BEND7 PTHR35068:SF1 BEN DOMAIN-CONTAINING PROTEIN 7 BEN DOMAIN-CONTAINING PROTEIN 7 platelet activation#GO:0030168;blood coagulation#GO:0007596;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;response to stress#GO:0006950;response to wounding#GO:0009611;immune response#GO:0006955;coagulation#GO:0050817;cellular process#GO:0009987;cell communication#GO:0007154;regulation of biological quality#GO:0065008;wound healing#GO:0042060;immune system process#GO:0002376;cell activation#GO:0001775;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;signaling#GO:0023052;hemostasis#GO:0007599;regulation of biological process#GO:0050789 MONDO|Ensembl=ENSMODG00000016237.6|UniProtKB=F7AYG9 F7AYG9 PTHR11243:SF15 GROWTH FACTOR RECEPTOR-BOUND PROTEIN RAS-ASSOCIATED AND PLECKSTRIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;signaling#GO:0023052;cell morphogenesis#GO:0000902;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;intracellular signal transduction#GO:0035556;anatomical structure development#GO:0048856;cell communication#GO:0007154 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000036637.1|UniProtKB=A0A5F8HBC0 A0A5F8HBC0 PTHR23505:SF4 SPINSTER SPHINGOSINE-1-PHOSPHATE TRANSPORTER SPNS2 intramembrane lipid carrier activity#GO:0140303;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 G protein-coupled receptor signaling pathway#GO:0007186;lipid localization#GO:0010876;cell communication#GO:0007154;localization#GO:0051179;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;transport#GO:0006810;establishment of localization#GO:0051234;cellular process#GO:0009987;signal transduction#GO:0007165;macromolecule localization#GO:0033036;biological regulation#GO:0065007;lipid transport#GO:0006869 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000014243.4|UniProtKB=A0A5F8GXJ2 A0A5F8GXJ2 SEC24A PTHR13803:SF1 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24A SNARE binding#GO:0000149;zinc ion binding#GO:0008270;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169 vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;COPII-coated vesicle budding#GO:0090114 organelle#GO:0043226;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;coated membrane#GO:0048475;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000008525.4|UniProtKB=F7DHF8 F7DHF8 FGFR2 PTHR24416:SF130 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 2 fibroblast growth factor binding#GO:0017134;signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740;protein kinase activity#GO:0004672;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;response to fibroblast growth factor#GO:0071774;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;tube development#GO:0035295;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;angiogenesis#GO:0001525;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636 MONDO|Ensembl=ENSMODG00000017036.4|UniProtKB=A0A5F8GEJ6 A0A5F8GEJ6 UCKL1 PTHR10285:SF68 URIDINE KINASE URIDINE-CYTIDINE KINASE-LIKE 1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172;kinase#PC00137 Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149;Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150 MONDO|Ensembl=ENSMODG00000015048.4|UniProtKB=F7FUN0 F7FUN0 FLNC PTHR38537:SF12 JITTERBUG, ISOFORM N FILAMIN-C MONDO|Ensembl=ENSMODG00000001273.4|UniProtKB=F7CIF4 F7CIF4 MYH16 PTHR45615:SF50 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-16 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824 membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000047999.1|UniProtKB=A0A5F8H6I7 A0A5F8H6I7 PTHR10037:SF221 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 9 SUBUNIT ALPHA transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium channel activity#GO:0005272;passive transmembrane transporter activity#GO:0022803;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;voltage-gated sodium channel activity#GO:0005248;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;sensory perception#GO:0007600;nervous system process#GO:0050877;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;action potential#GO:0001508;sodium ion transport#GO:0006814;sensory perception of pain#GO:0019233;system process#GO:0003008;transmission of nerve impulse#GO:0019226;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axon#GO:0030424;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transporter complex#GO:1990351 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000021315.4|UniProtKB=A0ACM8QK06 A0ACM8QK06 NLGN1 PTHR43903:SF2 NEUROLIGIN NEUROLIGIN-1 synaptic membrane#GO:0097060;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;organelle#GO:0043226 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000028100.2|UniProtKB=K7E070 K7E070 PTHR16083:SF3 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 27 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004484.4|UniProtKB=F6VRG3 F6VRG3 FAM222A PTHR16070:SF2 PROTEIN FAM222A-RELATED PROTEIN FAM222A MONDO|Ensembl=ENSMODG00000020670.3|UniProtKB=F7E5I9 F7E5I9 PDGFRA PTHR24416:SF52 TYROSINE-PROTEIN KINASE RECEPTOR PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838 positive regulation of cellular process#GO:0048522;skeletal system morphogenesis#GO:0048705;biological regulation#GO:0065007;cell migration#GO:0016477;multicellular organismal process#GO:0032501;developmental process#GO:0032502;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell motility#GO:0048870;animal organ morphogenesis#GO:0009887;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;embryo development#GO:0009790;cell surface receptor signaling pathway#GO:0007166;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;skeletal system development#GO:0001501 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Angiogenesis#P00005>PDGFR#P00230;PDGF signaling pathway#P00047>PDGF receptor A#P01158 MONDO|Ensembl=ENSMODG00000021166.3|UniProtKB=F6XX93 F6XX93 HERPUD2 PTHR12943:SF5 HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UBIQUITIN-LIKE DOMAIN MEMBER 2 PROTEIN biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 MONDO|Ensembl=ENSMODG00000004311.4|UniProtKB=F6X734 F6X734 CCDC83 PTHR21468:SF1 HSD9 COILED-COIL DOMAIN-CONTAINING PROTEIN 83 MONDO|Ensembl=ENSMODG00000042096.1|UniProtKB=A0A5F8GQT4 A0A5F8GQT4 LOC100023127 PTHR26453:SF33 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002875.4|UniProtKB=F7E201 F7E201 E2F1 PTHR12081:SF43 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F1 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000010757.3|UniProtKB=F7FWH7 F7FWH7 XKR8 PTHR16024:SF8 XK-RELATED PROTEIN XK-RELATED PROTEIN 8 lipid localization#GO:0010876;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;endocytosis#GO:0006897;membrane invagination#GO:0010324;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277;import into cell#GO:0098657;cellular process#GO:0009987;endomembrane system organization#GO:0010256;localization#GO:0051179;anatomical structure development#GO:0048856;programmed cell death#GO:0012501;cell death#GO:0008219;organophosphate ester transport#GO:0015748;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;phagocytosis#GO:0006909;developmental process#GO:0032502;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;lipid transport#GO:0006869;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000010525.3|UniProtKB=F7DQJ0 F7DQJ0 CEBPD PTHR23334:SF3 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN DELTA transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000012118.3|UniProtKB=A0A5F8HGN0 A0A5F8HGN0 EGR1 PTHR23235:SF42 KRUEPPEL-LIKE TRANSCRIPTION FACTOR EARLY GROWTH RESPONSE PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 nervous system process#GO:0050877;cognition#GO:0050890;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system process#GO:0003008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501 C2H2 zinc finger transcription factor#PC00248 Gonadotropin-releasing hormone receptor pathway#P06664>EGR1#G06672;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>EGR#P05931;Gonadotropin-releasing hormone receptor pathway#P06664>EGR1#G06887;CCKR signaling map#P06959>EGR1#P07192;Gonadotropin-releasing hormone receptor pathway#P06664>EGR1#P06837 MONDO|Ensembl=ENSMODG00000018756.4|UniProtKB=F7EEQ2 F7EEQ2 HJV PTHR31428:SF3 RGM DOMAIN FAMILY MEMBER DRAG-1 HEMOJUVELIN coreceptor activity#GO:0015026;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235 MONDO|Ensembl=ENSMODG00000029719.2|UniProtKB=K7E5M4 K7E5M4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009610.4|UniProtKB=F6S0S8 F6S0S8 PTHR12253:SF19 RH14732P GROUP 3 SECRETORY PHOSPHOLIPASE A2 MONDO|Ensembl=ENSMODG00000006811.4|UniProtKB=A0A5F8GJK8 A0A5F8GJK8 NDRG2 PTHR11034:SF17 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG2 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000022703.3|UniProtKB=H9H6S9 H9H6S9 LOC100619597 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018912.4|UniProtKB=A0A5F8HEI7 A0A5F8HEI7 RUNX2 PTHR11950:SF7 RUNT RELATED RUNT-RELATED TRANSCRIPTION FACTOR 2 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cellular process#GO:0009987;skeletal system development#GO:0001501;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell development#GO:0048468;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;connective tissue development#GO:0061448;neurogenesis#GO:0022008;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of nucleobase-containing compound metabolic process#GO:0019219;chondrocyte differentiation#GO:0002062;tissue development#GO:0009888;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;cartilage development#GO:0051216;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;ossification#GO:0001503;regulation of developmental process#GO:0050793 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;Runt transcription factor#PC00254 MONDO|Ensembl=ENSMODG00000020579.4|UniProtKB=F7A1N7 F7A1N7 BEND4 PTHR35082:SF1 BEN DOMAIN-CONTAINING PROTEIN 4 BEN DOMAIN-CONTAINING PROTEIN 4 MONDO|Ensembl=ENSMODG00000011077.4|UniProtKB=A0A5F8HCG8 A0A5F8HCG8 PDCD11 PTHR23270:SF10 PROGRAMMED CELL DEATH PROTEIN 11 PRE-RRNA PROCESSING PROTEIN RRP5 PROTEIN RRP5 HOMOLOG snoRNA binding#GO:0030515;binding#GO:0005488;nucleic acid binding#GO:0003676;U3 snoRNA binding#GO:0034511;RNA binding#GO:0003723 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000022616.3|UniProtKB=H9H888 H9H888 KLF15 PTHR23235:SF44 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 15 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016521.4|UniProtKB=F7EQ37 F7EQ37 PMEPA1 PTHR16514:SF5 LOW DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING 4A PROTEIN TMEPAI protein binding#GO:0005515;binding#GO:0005488 negative regulation of response to stimulus#GO:0048585;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 early endosome membrane#GO:0031901;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000000281.4|UniProtKB=H9H5V9 H9H5V9 TLE2 PTHR10814:SF4 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 2 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 MONDO|Ensembl=ENSMODG00000007912.2|UniProtKB=F7GII6 F7GII6 SNRPA PTHR10501:SF63 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;snRNA binding#GO:0017069 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;U1 snRNP#GO:0005685;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 mRNA splicing#P00058>U1#P01479 MONDO|Ensembl=ENSMODG00000009839.4|UniProtKB=A0A5F8H7N4 A0A5F8H7N4 FARS2 PTHR11538:SF41 PHENYLALANYL-TRNA SYNTHETASE PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000004956.4|UniProtKB=F7FX72 F7FX72 PIGN PTHR12250:SF0 PHOSPHATIDYLINOSITOL GLYCAN, CLASS N GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780 lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 extracellular matrix glycoprotein#PC00100 MONDO|Ensembl=ENSMODG00000010089.4|UniProtKB=F6XM86 F6XM86 HABP2 PTHR24278:SF29 COAGULATION FACTOR FACTOR VII-ACTIVATING PROTEASE serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000002527.4|UniProtKB=F7B8S0 F7B8S0 PMCH PTHR12091:SF0 MELANIN-CONCENTRATING HORMONE PRO-MCH G protein-coupled receptor binding#GO:0001664;neuropeptide receptor binding#GO:0071855;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 peptide hormone#PC00179;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000044023.1|UniProtKB=A0A5F8GH98 A0A5F8GH98 TMED2 PTHR22811:SF50 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 2 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;cellular component organization#GO:0016043;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179 endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000037938.1|UniProtKB=A0A5F8HI80 A0A5F8HI80 PTHR26451:SF344 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10J1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000980.4|UniProtKB=F7ESD5 F7ESD5 ATF6 PTHR46164:SF1 ATF6, ISOFORM C CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-6 ALPHA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;response to unfolded protein#GO:0006986;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Apoptosis signaling pathway#P00006>ATF#P00302 MONDO|Ensembl=ENSMODG00000019210.4|UniProtKB=F6ZI83 F6ZI83 PPEF2 PTHR45668:SF2 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE WITH EF-HANDS 2 Hsp90 protein binding#GO:0051879;heat shock protein binding#GO:0031072;binding#GO:0005488;protein binding#GO:0005515 negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000011813.4|UniProtKB=F7CB96 F7CB96 DNAJC18 PTHR43908:SF2 AT29763P-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 18 heat shock protein binding#GO:0031072;binding#GO:0005488;protein-folding chaperone binding#GO:0051087;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 cellular response to misfolded protein#GO:0071218;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;response to misfolded protein#GO:0051788;primary metabolic process#GO:0044238;response to topologically incorrect protein#GO:0035966;protein folding#GO:0006457;response to stimulus#GO:0050896 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000015993.4|UniProtKB=F6Y6M0 F6Y6M0 TRIM26 PTHR24103:SF369 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 26 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 immune system process#GO:0002376;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000005033.4|UniProtKB=A0A5F8GZM3 A0A5F8GZM3 AQP11 PTHR21191:SF7 AQUAPORIN AQUAPORIN-11 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 biological regulation#GO:0065007;homeostatic process#GO:0042592;cellular process#GO:0009987;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;regulation of cell size#GO:0008361;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;intracellular chemical homeostasis#GO:0055082;cellular component organization or biogenesis#GO:0071840;chemical homeostasis#GO:0048878;regulation of anatomical structure size#GO:0090066 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000012952.4|UniProtKB=A0A5F8GIF4 A0A5F8GIF4 PTHR24110:SF3 CENTROSOMAL PROTEIN OF 78 KDA CENTROSOMAL PROTEIN OF 78 KDA cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cilium#GO:0005929;centrosome#GO:0005813;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000009315.4|UniProtKB=F7GJY4 F7GJY4 ABCC4 PTHR24223:SF357 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 4 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000001757.5|UniProtKB=F6WZC2 F6WZC2 TMCC2 PTHR17613:SF9 CEREBRAL PROTEIN-11-RELATED TRANSMEMBRANE AND COILED-COIL DOMAINS PROTEIN 2 cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000011205.4|UniProtKB=F6SQD6 F6SQD6 PTHR24289:SF13 STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE STEROID 17-ALPHA-HYDROXYLASE_17,20 LYASE catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 ketone metabolic process#GO:0042180;primary metabolic process#GO:0044238;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;biosynthetic process#GO:0009058;hormone biosynthetic process#GO:0042446;steroid metabolic process#GO:0008202;olefinic compound metabolic process#GO:0120254;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;regulation of biological quality#GO:0065008 MONDO|Ensembl=ENSMODG00000045717.1|UniProtKB=A0A5F8G610 A0A5F8G610 PTHR38499:SF1 ADIPOGENIN ADIPOGENIN MONDO|Ensembl=ENSMODG00000010533.4|UniProtKB=F6ZF42 F6ZF42 ARAP3 PTHR45899:SF4 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;lipid binding#GO:0008289;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;phospholipid binding#GO:0005543;enzyme activator activity#GO:0008047 biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of actin filament-based process#GO:0032970 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000005228.4|UniProtKB=F6ZCK3 F6ZCK3 ADCK1 PTHR43173:SF19 ABC1 FAMILY PROTEIN AARF DOMAIN-CONTAINING PROTEIN KINASE 1 cellular component organization or biogenesis#GO:0071840;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592;mitochondrion organization#GO:0007005;cellular process#GO:0009987;lipid homeostasis#GO:0055088;cellular component organization#GO:0016043;organelle organization#GO:0006996 organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000000700.4|UniProtKB=F6WLQ8 F6WLQ8 OCA2 PTHR43568:SF2 P PROTEIN P PROTEIN cellular process#GO:0009987;melanocyte differentiation#GO:0030318;developmental pigmentation#GO:0048066;pigment metabolic process#GO:0042440;phenol-containing compound biosynthetic process#GO:0046189;biosynthetic process#GO:0009058;pigment biosynthetic process#GO:0046148;developmental process#GO:0032502;secondary metabolite biosynthetic process#GO:0044550;metabolic process#GO:0008152;secondary metabolic process#GO:0019748;cellular developmental process#GO:0048869;phenol-containing compound metabolic process#GO:0018958;cell differentiation#GO:0030154;pigmentation#GO:0043473;melanin biosynthetic process#GO:0042438 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasmic vesicle membrane#GO:0030659;melanosome#GO:0042470;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000019925.4|UniProtKB=F7GFS5 F7GFS5 PTHR19134:SF554 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ETA hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856 protein phosphatase#PC00195;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000017103.4|UniProtKB=F6UKH1 F6UKH1 KRTCAP2 PTHR32001:SF1 KERATINOCYTE-ASSOCIATED PROTEIN 2 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT KCP2 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 MONDO|Ensembl=ENSMODG00000019090.3|UniProtKB=F7FNB3 F7FNB3 MOB1B PTHR22599:SF63 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 1B enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;hippo signaling#GO:0035329;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000009728.3|UniProtKB=F6XSJ5 F6XSJ5 TCP11L1 PTHR12832:SF15 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 T-COMPLEX PROTEIN 11-LIKE PROTEIN 1 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000007568.4|UniProtKB=F7FPI6 F7FPI6 IVNS1ABP PTHR24412:SF396 KELCH PROTEIN INFLUENZA VIRUS NS1A-BINDING PROTEIN enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000008572.4|UniProtKB=F7CWN5 F7CWN5 PRKAR1B PTHR11635:SF126 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE I-BETA REGULATORY SUBUNIT protein kinase binding#GO:0019901;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;binding#GO:0005488;molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;protein kinase A binding#GO:0051018;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;kinase inhibitor activity#GO:0019210;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;nucleotide binding#GO:0000166 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Hedgehog signaling pathway#P00025>PKA#P00682;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Gonadotropin-releasing hormone receptor pathway#P06664>PKA#P06782;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Endothelin signaling pathway#P00019>PKA#P00570;GABA-B receptor II signaling#P05731>PKA#P05752;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050 MONDO|Ensembl=ENSMODG00000017644.4|UniProtKB=F6Z964 F6Z964 SLC28A2 PTHR10590:SF11 SODIUM/NUCLEOSIDE COTRANSPORTER SODIUM_NUCLEOSIDE COTRANSPORTER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;nucleoside transmembrane transporter activity#GO:0005337;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;symporter activity#GO:0015293;carbohydrate derivative transmembrane transporter activity#GO:1901505;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;nucleobase-containing compound transmembrane transporter activity#GO:0015932 nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;nucleobase-containing compound transport#GO:0015931;homeostatic process#GO:0042592;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;retina homeostasis#GO:0001895;localization#GO:0051179;multicellular organismal-level homeostasis#GO:0048871;tissue homeostasis#GO:0001894 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000003310.4|UniProtKB=F7DYZ9 F7DYZ9 SLC1A4 PTHR11958:SF20 SODIUM/DICARBOXYLATE SYMPORTER-RELATED NEUTRAL AMINO ACID TRANSPORTER A amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556;active transmembrane transporter activity#GO:0022804;acidic amino acid transmembrane transporter activity#GO:0015172;sodium ion transmembrane transporter activity#GO:0015081;L-amino acid transmembrane transporter activity#GO:0015179;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic cation transmembrane transporter activity#GO:0008324;sodium:dicarboxylate symporter activity#GO:0017153;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171 L-glutamate import#GO:0051938;localization#GO:0051179;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;carboxylic acid transport#GO:0046942;acidic amino acid transport#GO:0015800;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;establishment of localization#GO:0051234;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;L-glutamate transmembrane transport#GO:0015813;dicarboxylic acid transport#GO:0006835 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000010358.5|UniProtKB=F6RNS9 F6RNS9 PDCD7 PTHR48190:SF2 PROGRAMMED CELL DEATH PROTEIN 7 PROGRAMMED CELL DEATH PROTEIN 7 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 MONDO|Ensembl=ENSMODG00000016326.4|UniProtKB=A0A5F8GLP9 A0A5F8GLP9 CDK15 PTHR24056:SF159 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 15 protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;cyclin-dependent protein kinase activity#GO:0097472;catalytic activity, acting on a protein#GO:0140096;cyclin binding#GO:0030332;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;protein kinase complex#GO:1902911;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000005497.4|UniProtKB=F7BXL6 F7BXL6 TRABD PTHR21530:SF7 PHEROMONE SHUTDOWN PROTEIN TRAB DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000012750.4|UniProtKB=F6T0C6 F6T0C6 BRMS1L PTHR21964:SF16 BREAST CANCER METASTASIS-SUPPRESSOR 1 BREAST CANCER METASTASIS-SUPPRESSOR 1-LIKE PROTEIN enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515;histone deacetylase binding#GO:0042826 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000024310.2|UniProtKB=F7EHW8 F7EHW8 SMCO4 PTHR34644:SF2 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 MONDO|Ensembl=ENSMODG00000015516.4|UniProtKB=F6VYP1 F6VYP1 XPO6 PTHR21452:SF4 EXPORTIN-6 EXPORTIN-6 establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein export from nucleus#GO:0006611;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913 MONDO|Ensembl=ENSMODG00000016796.4|UniProtKB=F7FVV1 F7FVV1 METTL25B PTHR12496:SF2 CGI-41 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 25B RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000000160.4|UniProtKB=F6XSA8 F6XSA8 CLGN PTHR11073:SF7 CALRETICULIN AND CALNEXIN CALMEGIN calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000013757.4|UniProtKB=F6WS11 F6WS11 FKBP5 PTHR10516:SF26 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5 catalytic activity#GO:0003824;cis-trans isomerase activity#GO:0016859;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000002931.5|UniProtKB=A0A5F8GEJ7 A0A5F8GEJ7 SLC6A9 PTHR11616:SF263 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 1 monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;import into cell#GO:0098657;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;amino acid transport#GO:0006865;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;glycine transport#GO:0015816 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000021466.6|UniProtKB=F7DXH2 F7DXH2 LPIN2 PTHR12181:SF11 LIPIN PHOSPHATIDATE PHOSPHATASE LPIN2 catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;hydrolase activity#GO:0016787 regulation of gene expression#GO:0010468;neutral lipid metabolic process#GO:0006638;regulation of biosynthetic process#GO:0009889;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;cellular response to insulin stimulus#GO:0032869;acylglycerol metabolic process#GO:0006639;fatty acid metabolic process#GO:0006631;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;biosynthetic process#GO:0009058;response to peptide hormone#GO:0043434;regulation of nucleobase-containing compound metabolic process#GO:0019219;triglyceride biosynthetic process#GO:0019432;cellular response to nitrogen compound#GO:1901699;monocarboxylic acid catabolic process#GO:0072329;positive regulation of DNA-templated transcription#GO:0045893;lipid biosynthetic process#GO:0008610;carboxylic acid catabolic process#GO:0046395;positive regulation of cellular process#GO:0048522;glycerolipid biosynthetic process#GO:0045017;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;cellular response to peptide hormone stimulus#GO:0071375;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;primary metabolic process#GO:0044238;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;lipid catabolic process#GO:0016042;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to hormone#GO:0009725;fatty acid catabolic process#GO:0009062;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;glycerolipid metabolic process#GO:0046486;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;monocarboxylic acid metabolic process#GO:0032787;response to endogenous stimulus#GO:0009719;carboxylic acid metabolic process#GO:0019752 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;nucleus#GO:0005634;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000017901.3|UniProtKB=F7FGF9 F7FGF9 PTHR11654:SF91 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 5 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000013635.4|UniProtKB=F6UVT2 F6UVT2 UPK3B PTHR15446:SF15 UROPLAKIN III UROPLAKIN-3B membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000044326.1|UniProtKB=A0A5F8GHX0 A0A5F8GHX0 LOC100021916 PTHR26450:SF67 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51V1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016712.4|UniProtKB=A0A5F8G9U3 A0A5F8G9U3 INSRR PTHR24416:SF338 TYROSINE-PROTEIN KINASE RECEPTOR INSULIN RECEPTOR-RELATED PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;protein kinase activity#GO:0004672 positive regulation of cellular process#GO:0048522;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular response to nitrogen compound#GO:1901699;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;cellular response to insulin stimulus#GO:0032869;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;cellular response to peptide hormone stimulus#GO:0071375;homeostatic process#GO:0042592;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;chemical homeostasis#GO:0048878;regulation of MAPK cascade#GO:0043408;glucose homeostasis#GO:0042593;regulation of JNK cascade#GO:0046328;carbohydrate homeostasis#GO:0033500;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;insulin-like growth factor receptor signaling pathway#GO:0048009;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;cellular response to endogenous stimulus#GO:0071495;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;positive regulation of signaling#GO:0023056 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transferase complex, transferring phosphorus-containing groups#GO:0061695;axon#GO:0030424;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;protein kinase complex#GO:1902911;signaling receptor complex#GO:0043235;transferase complex#GO:1990234 transmembrane signal receptor#PC00197 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885 MONDO|Ensembl=ENSMODG00000024346.1|UniProtKB=F7B5G2 F7B5G2 LOC100011206 PTHR11904:SF12 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763 nucleoside phosphate biosynthetic process#GO:1901293;NAD+ metabolic process#GO:0019674;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;pyridine-containing compound metabolic process#GO:0072524;purine nucleoside metabolic process#GO:0042278;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine-containing compound catabolic process#GO:0072523;purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule metabolic process#GO:0055086;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;nucleoside catabolic process#GO:0009164;nucleobase-containing small molecule catabolic process#GO:0034656;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172;kinase#PC00137 Xanthine and guanine salvage pathway#P02788>Guanosine phosphorylase#P03250;Adenine and hypoxanthine salvage pathway#P02723>Deoxyinosine phosphorylase#P02812;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphorylase#P02805;Purine metabolism#P02769>Nucleoside Phosphorylase#P03115;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine phosphorylase#P02808;Adenine and hypoxanthine salvage pathway#P02723>Inosine phosphorylase#P02813;Xanthine and guanine salvage pathway#P02788>Deoxyguanosine phosphorylase#P03248 MONDO|Ensembl=ENSMODG00000001065.4|UniProtKB=F6YQY7 F6YQY7 CHI3L1 PTHR11177:SF202 CHITINASE CHITINASE-3-LIKE PROTEIN 1 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;amino sugar catabolic process#GO:0046348;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000005192.5|UniProtKB=F7DMX5 F7DMX5 ADAMTS4 PTHR13723:SF38 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 4 metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000001030.4|UniProtKB=F6ZF75 F6ZF75 MALSU1 PTHR21043:SF0 IOJAP SUPERFAMILY ORTHOLOG MITOCHONDRIAL ASSEMBLY OF RIBOSOMAL LARGE SUBUNIT PROTEIN 1 ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;ribosomal large subunit binding#GO:0043023;binding#GO:0005488 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;cellular component assembly#GO:0022607;mitochondrial ribosome assembly#GO:0061668;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex assembly#GO:0065003;mitochondrial large ribosomal subunit assembly#GO:1902775;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;ribosome biogenesis#GO:0042254;protein-RNA complex assembly#GO:0022618 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000004213.4|UniProtKB=F6XQF9 F6XQF9 EXOSC1 PTHR12686:SF8 3'-5' EXORIBONUCLEASE CSL4-RELATED EXOSOME COMPLEX COMPONENT CSL4 rRNA processing#GO:0006364;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;ribonucleoprotein complex biogenesis#GO:0022613;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;negative regulation of gene expression#GO:0010629;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 exoribonuclease#PC00099;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000001917.5|UniProtKB=F6W137 F6W137 PTHR45161:SF1 CYTOSKELETON-ASSOCIATED PROTEIN 4 CYTOSKELETON-ASSOCIATED PROTEIN 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum#GO:0005791;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 MONDO|Ensembl=ENSMODG00000003983.4|UniProtKB=A0A5F8H4Q7 A0A5F8H4Q7 MUSK PTHR24416:SF317 TYROSINE-PROTEIN KINASE RECEPTOR MUSCLE, SKELETAL RECEPTOR TYROSINE-PROTEIN KINASE transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;Wnt-protein binding#GO:0017147;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001794.4|UniProtKB=F6WIC9 F6WIC9 STX4 PTHR19957:SF97 SYNTAXIN SYNTAXIN-4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 secretion by cell#GO:0032940;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;secretion#GO:0046903;export from cell#GO:0140352;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;exocytosis#GO:0006887;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025;macromolecule localization#GO:0033036 intracellular anatomical structure#GO:0005622;SNARE complex#GO:0031201;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 MONDO|Ensembl=ENSMODG00000020332.3|UniProtKB=F7FWY0 F7FWY0 GDNF PTHR12173:SF1 GDNF SUBFAMILY OF TGF-BETA FAMILY GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;generation of neurons#GO:0048699;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;neuron development#GO:0048666;system development#GO:0048731 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 neurotrophic factor#PC00163;intercellular signal molecule#PC00207;growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000009400.4|UniProtKB=F7C6A4 F7C6A4 WDCP PTHR14897:SF5 WD REPEAT AND COILED-COIL-CONTAINING PROTEIN WD REPEAT AND COILED-COIL-CONTAINING PROTEIN protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899 MONDO|Ensembl=ENSMODG00000009011.4|UniProtKB=F7BPV8 F7BPV8 CSRP3 PTHR24215:SF1 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 3 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;tissue development#GO:0009888;blood circulation#GO:0008015;cellular developmental process#GO:0048869;heart contraction#GO:0060047;system process#GO:0003008;muscle contraction#GO:0006936;developmental process#GO:0032502;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;striated muscle contraction#GO:0006941;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;supramolecular fiber organization#GO:0097435;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system process#GO:0003013;organelle assembly#GO:0070925;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;cardiac muscle contraction#GO:0060048;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;heart process#GO:0003015;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108 membraneless organelle#GO:0043228;sarcomere#GO:0030017;I band#GO:0031674;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;nucleus#GO:0005634;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000050183.1|UniProtKB=A0A5F8GPX4 A0A5F8GPX4 PTHR12485:SF1 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 7 electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060 membrane#GO:0016020;oxidoreductase complex#GO:1990204;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;respiratory chain complex I#GO:0045271;transporter complex#GO:1990351;organelle membrane#GO:0031090;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000015904.4|UniProtKB=F7AFT9 F7AFT9 PTHR12419:SF117 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 3 cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of biological quality#GO:0065008;protein stabilization#GO:0050821;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000021312.3|UniProtKB=F7G392 F7G392 TBL1XR1 PTHR22846:SF40 WD40 REPEAT PROTEIN F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN TBL1XR1 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892 membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;protein-containing complex#GO:0032991;transcription repressor complex#GO:0017053;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Wnt signaling pathway#P00057>Ebi#P01453 MONDO|Ensembl=ENSMODG00000043910.1|UniProtKB=A0A5F8GTR1 A0A5F8GTR1 LOC100021208 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020898.4|UniProtKB=A0A5F8GQW8 A0A5F8GQW8 XYLT2 PTHR46025:SF1 XYLOSYLTRANSFERASE OXT XYLOSYLTRANSFERASE 2 pentosyltransferase activity#GO:0016763;xylosyltransferase activity#GO:0042285;catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-xylosyltransferase activity#GO:0035252;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238 transferase#PC00220 MONDO|Ensembl=ENSMODG00000006963.5|UniProtKB=A0A5F8GNC9 A0A5F8GNC9 PLXND1 PTHR22625:SF7 PLEXIN PLEXIN-D1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 positive regulation of cell differentiation#GO:0045597;cell surface receptor signaling pathway#GO:0007166;regulation of axonogenesis#GO:0050770;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;positive regulation of cell development#GO:0010720;cellular component assembly#GO:0022607;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;positive regulation of axonogenesis#GO:0050772;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;negative regulation of biological process#GO:0048519;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;synapse assembly#GO:0007416;positive regulation of developmental process#GO:0051094;regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;negative regulation of cell adhesion#GO:0007162;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;synapse organization#GO:0050808;positive regulation of cell projection organization#GO:0031346;system development#GO:0048731;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017730.4|UniProtKB=F7ELF5 F7ELF5 FABP7 PTHR11955:SF57 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, BRAIN lipid binding#GO:0008289;fatty acid binding#GO:0005504;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094 macromolecule localization#GO:0033036;lipid transport#GO:0006869;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;lipid localization#GO:0010876;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;localization#GO:0051179;fatty acid transport#GO:0015908 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000038715.1|UniProtKB=A0A5F8HEF0 A0A5F8HEF0 MED9 PTHR20844:SF0 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 9 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000018297.4|UniProtKB=F6PW24 F6PW24 AKIRIN2 PTHR13293:SF8 AKIRIN-RELATED AKIRIN-2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of gene expression#GO:0010468;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of response to biotic stimulus#GO:0002831;positive regulation of RNA metabolic process#GO:0051254;positive regulation of response to external stimulus#GO:0032103;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000016740.4|UniProtKB=F7BYP0 F7BYP0 NEFM PTHR45652:SF3 GLIAL FIBRILLARY ACIDIC PROTEIN NEUROFILAMENT MEDIUM POLYPEPTIDE structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 intermediate filament cytoskeleton organization#GO:0045104;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;intermediate filament bundle assembly#GO:0045110;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109 neuron projection#GO:0043005;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882;postsynapse#GO:0098794;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000044564.1|UniProtKB=A0A5F8GDT7 A0A5F8GDT7 PTHR21223:SF4 CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN 1 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;ciliary transition zone#GO:0035869;microtubule organizing center#GO:0005815;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000013243.3|UniProtKB=F7DIR0 F7DIR0 NHERF4 PTHR14191:SF20 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR NHE-RF4 protein binding#GO:0005515;protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular process#GO:0009987;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;localization#GO:0051179;cellular localization#GO:0051641 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014766.4|UniProtKB=F7GGS1 F7GGS1 NKIRAS2 PTHR46152:SF2 NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000017217.4|UniProtKB=F6WYJ7 F6WYJ7 CIMIP2A PTHR47299:SF1 PROTEIN FAM166A CILIARY MICROTUBULE INNER PROTEIN 2A MONDO|Ensembl=ENSMODG00000021512.5|UniProtKB=F7FSG5 F7FSG5 TAF4B PTHR15138:SF17 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4B binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000015911.4|UniProtKB=F6ZRY0 F6ZRY0 STMN4 PTHR10104:SF6 STATHMIN STATHMIN-4 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488 protein-containing complex disassembly#GO:0032984;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of microtubule-based process#GO:0032886;supramolecular fiber organization#GO:0097435;system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;microtubule polymerization or depolymerization#GO:0031109;biological regulation#GO:0065007;protein depolymerization#GO:0051261;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of microtubule polymerization or depolymerization#GO:0031110;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;cellular component disassembly#GO:0022411;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;regulation of microtubule cytoskeleton organization#GO:0070507;microtubule depolymerization#GO:0007019;neuron differentiation#GO:0030182;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 Cytoskeletal regulation by Rho GTPase#P00016>Op18/stathmin#P00513 MONDO|Ensembl=ENSMODG00000007882.5|UniProtKB=F6ZH64 F6ZH64 PHOX2A PTHR24329:SF303 HOMEOBOX PROTEIN ARISTALESS PAIRED MESODERM HOMEOBOX PROTEIN 2A DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000041881.1|UniProtKB=K7E022 K7E022 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000010478.2|UniProtKB=F7ESM2 F7ESM2 DHX32 PTHR18934:SF88 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX32-RELATED macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000018833.3|UniProtKB=F7GKB5 F7GKB5 CDC42SE1 PTHR13502:SF3 CDC42 SMALL EFFECTOR PROTEIN HOMOLOG CDC42 SMALL EFFECTOR PROTEIN 1 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000051218.1|UniProtKB=A0A5F8H0Y1 A0A5F8H0Y1 RPL22 PTHR10064:SF2 60S RIBOSOMAL PROTEIN L22 LARGE RIBOSOMAL SUBUNIT PROTEIN EL22 nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000029320.2|UniProtKB=K7E3W3 K7E3W3 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000051582.1|UniProtKB=A0A5F8H2E5 A0A5F8H2E5 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005031.4|UniProtKB=F7EQW5 F7EQW5 SDHC PTHR10978:SF5 SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987 catalytic complex#GO:1902494;respiratory chain complex II (succinate dehydrogenase)#GO:0045273;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796 dehydrogenase#PC00092 TCA cycle#P00051>Succinate Dehydrogenase#P01273 MONDO|Ensembl=ENSMODG00000015970.4|UniProtKB=A0A5F8HIA8 A0A5F8HIA8 CREB1 PTHR45879:SF1 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;intracellular signaling cassette#GO:0141124;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Apoptosis signaling pathway#P00006>ATF#P00302;p38 MAPK pathway#P05918>CREB#P06027;Enkephalin release#P05913>CREB#P05971;Gonadotropin-releasing hormone receptor pathway#P06664>CREB#P06749;CCKR signaling map#P06959>CREB1#P07232;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 MONDO|Ensembl=ENSMODG00000023231.2|UniProtKB=F6UE98 F6UE98 SEMA4C PTHR11036:SF16 SEMAPHORIN SEMAPHORIN-4C molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 system development#GO:0048731;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;chemotaxis#GO:0006935;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon guidance#GO:0007411;axon development#GO:0061564;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;taxis#GO:0042330;response to chemical#GO:0042221;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175 cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000001824.4|UniProtKB=F6T5F9 F6T5F9 SLC45A3 PTHR19432:SF37 SUGAR TRANSPORTER SOLUTE CARRIER FAMILY 45 MEMBER 3 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000007642.3|UniProtKB=A0A5F8GLU3 A0A5F8GLU3 EZR PTHR23281:SF13 MERLIN/MOESIN/EZRIN/RADIXIN EZRIN binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 regulation of anatomical structure morphogenesis#GO:0022603;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of cellular process#GO:0048522;regulation of organelle assembly#GO:1902115;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087 intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;membraneless organelle#GO:0043228;cell junction#GO:0030054;adherens junction#GO:0005912;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;microvillus#GO:0005902;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;filopodium#GO:0030175;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000010656.4|UniProtKB=F6QUG9 F6QUG9 RANBP9 PTHR12864:SF56 RAN BINDING PROTEIN 9-RELATED RAN-BINDING PROTEIN 9 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cytoskeleton organization#GO:0007010;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;organelle organization#GO:0006996;ubiquitin-dependent protein catabolic process#GO:0006511;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007965.4|UniProtKB=F7DRH1 F7DRH1 EGLN2 PTHR12907:SF6 EGL NINE HOMOLOG-RELATED PROLYL HYDROXYLASE EGLN2 catalytic activity#GO:0003824;ferrous iron binding#GO:0008198;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;iron ion binding#GO:0005506;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;dioxygenase activity#GO:0051213;cation binding#GO:0043169 response to hypoxia#GO:0001666;regulation of apoptotic process#GO:0042981;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to decreased oxygen levels#GO:0036293;regulation of programmed cell death#GO:0043067;response to oxygen levels#GO:0070482;response to abiotic stimulus#GO:0009628;cellular response to hypoxia#GO:0071456;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Hypoxia response via HIF activation#P00030>Prolyl Hydroxylase#P00821 MONDO|Ensembl=ENSMODG00000017512.3|UniProtKB=F7F0U7 F7F0U7 SLC2A12 PTHR48023:SF2 D-XYLOSE-PROTON SYMPORTER-LIKE 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 12 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144 circulatory system development#GO:0072359;multicellular organismal process#GO:0032501;carbohydrate transmembrane transport#GO:0034219;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;multicellular organism development#GO:0007275;localization#GO:0051179;establishment of localization#GO:0051234;anatomical structure development#GO:0048856;transmembrane transport#GO:0055085;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;carbohydrate transport#GO:0008643;developmental process#GO:0032502;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000012957.4|UniProtKB=F7DC85 F7DC85 LONP2 PTHR10046:SF24 ATP DEPENDENT LON PROTEASE FAMILY MEMBER LON PROTEASE HOMOLOG 2, PEROXISOMAL catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824 localization#GO:0051179;protein metabolic process#GO:0019538;proteolysis#GO:0006508;protein targeting#GO:0006605;primary metabolic process#GO:0044238;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;establishment of protein localization#GO:0045184;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000027970.2|UniProtKB=F7BJM5 F7BJM5 PTHR44427:SF13 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 4-RELATED cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000050401.1|UniProtKB=A0A5F8G6E8 A0A5F8G6E8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000006943.4|UniProtKB=F6RGC2 F6RGC2 OPN3 PTHR24240:SF197 OPSIN OPSIN-3 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;cellular response to radiation#GO:0071478;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;detection of stimulus#GO:0051606;signal transduction#GO:0007165;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;cellular process#GO:0009987;biological regulation#GO:0065007;cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605 neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000678.4|UniProtKB=F6WMG0 F6WMG0 PPM1B PTHR47992:SF105 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1B hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000019801.4|UniProtKB=H9H7G7 H9H7G7 GPR119 PTHR22750:SF7 G-PROTEIN COUPLED RECEPTOR GLUCOSE-DEPENDENT INSULINOTROPIC RECEPTOR G protein-coupled receptor activity#GO:0004930;phosphatidylcholine binding#GO:0031210;signaling receptor activity#GO:0038023;phospholipid binding#GO:0005543;molecular transducer activity#GO:0060089;cation binding#GO:0043169;lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000038355.1|UniProtKB=A0A5F8H7M8 A0A5F8H7M8 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000003555.4|UniProtKB=F7DNI6 F7DNI6 PTHR11783:SF212 SULFOTRANSFERASE SULT SULFOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000051563.1|UniProtKB=A0A5F8G3H2 A0A5F8G3H2 NCEH1 PTHR23024:SF108 ARYLACETAMIDE DEACETYLASE NEUTRAL CHOLESTEROL ESTER HYDROLASE 1 catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;membrane#GO:0016020 deacetylase#PC00087 MONDO|Ensembl=ENSMODG00000025070.2|UniProtKB=F7G4F3 F7G4F3 VAMP3 PTHR45701:SF6 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 3 SNAP receptor activity#GO:0005484;syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090 localization#GO:0051179;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;vesicle fusion#GO:0006906;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;membrane fusion#GO:0061025;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174 intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944 membrane traffic protein#PC00150 Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423 MONDO|Ensembl=ENSMODG00000001408.4|UniProtKB=A0A5F8GFZ8 A0A5F8GFZ8 TMEM11 PTHR15099:SF2 PROTEIN PM1 TRANSMEMBRANE PROTEIN 11, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;mitochondrial membrane organization#GO:0007006;membrane organization#GO:0061024;mitochondrion organization#GO:0007005 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000010779.4|UniProtKB=F7CIK7 F7CIK7 SFMBT1 PTHR12247:SF77 POLYCOMB GROUP PROTEIN SCM-LIKE WITH FOUR MBT DOMAINS PROTEIN 1 protein binding#GO:0005515;histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000021052.3|UniProtKB=F6VJL1 F6VJL1 PTHR45476:SF1 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6 channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254 monoatomic anion transport#GO:0006820;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ion channel#PC00133 Nicotine pharmacodynamics pathway#P06587>CLIC6#P06611;Dopamine receptor mediated signaling pathway#P05912>CLIC6#P05968 MONDO|Ensembl=ENSMODG00000041507.1|UniProtKB=A0A5F8G871 A0A5F8G871 KCNK17 PTHR11003:SF340 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 17 voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000004164.4|UniProtKB=F6X2A9 F6X2A9 RGS3 PTHR46848:SF1 REGULATOR OF G-PROTEIN SIGNALING 3 REGULATOR OF G PROTEIN SIGNALING 3 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 MONDO|Ensembl=ENSMODG00000012275.4|UniProtKB=A0A5F8GK24 A0A5F8GK24 SF3B1 PTHR12097:SF0 SPLICING FACTOR 3B, SUBUNIT 1-RELATED SPLICING FACTOR 3B SUBUNIT 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618 U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;U2-type prespliceosome#GO:0071004;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;U2 snRNP#GO:0005686 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000007054.2|UniProtKB=F6UF84 F6UF84 OTOP2 PTHR21522:SF35 PROTON CHANNEL OTOP PROTON CHANNEL OTOP2 monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000023756.2|UniProtKB=F6TED5 F6TED5 SPRY4 PTHR12365:SF6 SPROUTY PROTEIN SPROUTY HOMOLOG 4 molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;kinase inhibitor activity#GO:0019210 negative regulation of cell communication#GO:0010648;regulation of Ras protein signal transduction#GO:0046578;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of response to stimulus#GO:0048585 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>SPRY#G01511;EGF receptor signaling pathway#P00018>Spry#P00541;FGF signaling pathway#P00021>Spry#P00626 MONDO|Ensembl=ENSMODG00000019897.4|UniProtKB=F6W5T2 F6W5T2 CKAP5 PTHR12609:SF0 MICROTUBULE ASSOCIATED PROTEIN XMAP215 CYTOSKELETON-ASSOCIATED PROTEIN 5 catalytic activity#GO:0003824;transferase activity#GO:0016740;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;establishment or maintenance of cell polarity#GO:0007163;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;mitotic cell cycle process#GO:1903047;microtubule organizing center organization#GO:0031023;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;cellular process#GO:0009987 intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;microtubule end#GO:1990752;kinetochore#GO:0000776;chromosome#GO:0005694;spindle pole#GO:0000922;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000003226.2|UniProtKB=F6TYS8 F6TYS8 LGALSL PTHR11346:SF98 GALECTIN GALECTIN-RELATED PROTEIN carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000014971.4|UniProtKB=A0A5F8GWI0 A0A5F8GWI0 TUBG1 PTHR11588:SF540 TUBULIN TUBULIN GAMMA CHAIN heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;microtubule polymerization#GO:0046785;spindle organization#GO:0007051;mitotic sister chromatid segregation#GO:0000070;microtubule polymerization or depolymerization#GO:0031109;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;sexual reproduction#GO:0019953;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;nuclear division#GO:0000280;mitotic spindle organization#GO:0007052;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815 tubulin#PC00228;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000038504.1|UniProtKB=A0A5F8HC70 A0A5F8HC70 APOE PTHR18976:SF2 APOLIPOPROTEIN APOLIPOPROTEIN E cholesterol transfer activity#GO:0120020;molecular function regulator activity#GO:0098772;sterol transfer activity#GO:0120015;transporter activity#GO:0005215;phospholipid binding#GO:0005543;enzyme activator activity#GO:0008047;lipid transfer activity#GO:0120013;molecular function activator activity#GO:0140677;lipid binding#GO:0008289;enzyme regulator activity#GO:0030234;binding#GO:0005488;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 cholesterol efflux#GO:0033344;cellular process#GO:0009987;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;steroid metabolic process#GO:0008202;lipid transport#GO:0006869;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;transport#GO:0006810;cholesterol metabolic process#GO:0008203;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;establishment of localization#GO:0051234;sterol transport#GO:0015918;sterol metabolic process#GO:0016125;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;homeostatic process#GO:0042592;organophosphate ester transport#GO:0015748;small molecule metabolic process#GO:0044281;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;localization#GO:0051179 vesicle#GO:0031982;very-low-density lipoprotein particle#GO:0034361;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-lipid complex#GO:0032994;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;lipoprotein particle#GO:1990777;membrane-bounded organelle#GO:0043227;plasma lipoprotein particle#GO:0034358;high-density lipoprotein particle#GO:0034364 apolipoprotein#PC00052;transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000013128.5|UniProtKB=A0A5F8HGT0 A0A5F8HGT0 NIN PTHR18905:SF11 NINEIN NINEIN supramolecular fiber organization#GO:0097435;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;centrosome localization#GO:0051642;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;microtubule anchoring at microtubule organizing center#GO:0072393;cellular component organization or biogenesis#GO:0071840;microtubule anchoring#GO:0034453;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;protein-containing complex#GO:0032991;ciliary transition fiber#GO:0097539;mitotic spindle pole#GO:0097431;microtubule cytoskeleton#GO:0015630;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;plasma membrane bounded cell projection#GO:0120025;mitotic spindle#GO:0072686;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spindle pole#GO:0000922;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229 PDGF signaling pathway#P00047>GSK3#P01153 MONDO|Ensembl=ENSMODG00000042195.1|UniProtKB=A0A5F8G4S2 A0A5F8G4S2 LOC100031194 PTHR26454:SF77 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014633.2|UniProtKB=F6YPC9 F6YPC9 CRIP1 PTHR46074:SF3 CYSTEINE-RICH PROTEIN CRIP FAMILY MEMBER CYSTEINE-RICH PROTEIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;zinc ion binding#GO:0008270 DNA damage response#GO:0006974;apoptotic signaling pathway#GO:0097190;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;cellular response to stress#GO:0033554;cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;intracellular signal transduction#GO:0035556;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;signaling#GO:0023052 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000042149.1|UniProtKB=F7CT20 F7CT20 LOC100030294 PTHR26453:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G7 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001980.4|UniProtKB=A0A5F8GP87 A0A5F8GP87 ERBB3 PTHR24416:SF88 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3 growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772 cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of biological process#GO:0048519;positive regulation of cell population proliferation#GO:0008284;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;nervous system development#GO:0007399;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;neuron differentiation#GO:0030182;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of epithelial cell proliferation#GO:0050679;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;epidermal growth factor receptor signaling pathway#GO:0007173;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;ERBB signaling pathway#GO:0038127;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGFR#P00542;Cadherin signaling pathway#P00012>EGFR#P00466 MONDO|Ensembl=ENSMODG00000025075.1|UniProtKB=F6RQ67 F6RQ67 LOC100016236 PTHR12002:SF84 CLAUDIN CLAUDIN-24 cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216 anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;apical junction complex#GO:0043296;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 cell junction protein#PC00070;tight junction#PC00214 MONDO|Ensembl=ENSMODG00000006652.2|UniProtKB=F7G3Z4 F7G3Z4 EIF5A PTHR11673:SF34 TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 5A-1 translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 MONDO|Ensembl=ENSMODG00000006644.2|UniProtKB=F7G494 F7G494 SBDS PTHR10927:SF1 RIBOSOME MATURATION PROTEIN SBDS RIBOSOME MATURATION PROTEIN SBDS RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000015916.4|UniProtKB=F6ZRD1 F6ZRD1 IFRD1 PTHR12354:SF6 INTERFERON-RELATED DEVELOPMENTAL REGULATOR INTERFERON-RELATED DEVELOPMENTAL REGULATOR 1 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000041727.1|UniProtKB=F6WFQ2 F6WFQ2 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000039660.1|UniProtKB=A0A5F8H9U2 A0A5F8H9U2 PTHR28654:SF1 AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN pattern specification process#GO:0007389;anatomical structure development#GO:0048856;negative regulation of MAPK cascade#GO:0043409;dorsal/ventral pattern formation#GO:0009953;negative regulation of protein metabolic process#GO:0051248;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;specification of symmetry#GO:0009799;regulation of protein modification process#GO:0031399;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regionalization#GO:0003002;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275;regulation of JNK cascade#GO:0046328;regulation of protein metabolic process#GO:0051246;determination of bilateral symmetry#GO:0009855;negative regulation of signal transduction#GO:0009968 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000028235.2|UniProtKB=A0A5F8GBD9 A0A5F8GBD9 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000049352.1|UniProtKB=A0A5F8GW89 A0A5F8GW89 RNF8 PTHR15067:SF9 E3 UBIQUITIN-PROTEIN LIGASE RNF8 E3 UBIQUITIN-PROTEIN LIGASE RNF8 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;histone binding#GO:0042393;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746 DNA damage response#GO:0006974;protein K48-linked ubiquitination#GO:0070936;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;ubiquitin-dependent protein catabolic process#GO:0006511;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;response to stimulus#GO:0050896;catabolic process#GO:0009056 site of double-strand break#GO:0035861;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000023886.3|UniProtKB=F7EAN8 F7EAN8 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 immune system process#GO:0002376;immune effector process#GO:0002252;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000004441.4|UniProtKB=A0A5F8HD85 A0A5F8HD85 PTHR47109:SF1 NUCLEOREDOXIN-LIKE PROTEIN 1 NUCLEOREDOXIN-LIKE PROTEIN 1 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000015674.3|UniProtKB=F7EHS7 F7EHS7 GDPD3 PTHR42758:SF3 PHOSPHATIDYLGLYCEROL PHOSPHOLIPASE C LYSOPHOSPHOLIPASE D GDPD3 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644;glycerolipid catabolic process#GO:0046503;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 hydrolase#PC00121;phospholipase#PC00186;lipase#PC00143 MONDO|Ensembl=ENSMODG00000044035.1|UniProtKB=A0A5F8HHB3 A0A5F8HHB3 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000015106.4|UniProtKB=F6RWK2 F6RWK2 PTHR10454:SF240 CASPASE CASPASE-10 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of programmed cell death#GO:0043067;regulation of neuron apoptotic process#GO:0043523;programmed cell death#GO:0012501;biological regulation#GO:0065007;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;positive regulation of neuron apoptotic process#GO:0043525;positive regulation of apoptotic process#GO:0043065 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Huntington disease#P00029>Caspase 8#P00808;FAS signaling pathway#P00020>Pro-Caspase10#P00598;Apoptosis signaling pathway#P00006>Caspase 10#P00295;Huntington disease#P00029>Pro-caspase 8#P00767;FAS signaling pathway#P00020>Caspase8#P00594;FAS signaling pathway#P00020>Pro-Caspase8#P00604;FAS signaling pathway#P00020>Caspase10#P00606;Apoptosis signaling pathway#P00006>Caspase 8#P00299 MONDO|Ensembl=ENSMODG00000038901.1|UniProtKB=A0A5F8GTI4 A0A5F8GTI4 PTHR45935:SF2 PROTEIN ZBED8-RELATED KRAB DOMAIN-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000000566.4|UniProtKB=F6X4G9 F6X4G9 LRRC2 PTHR45752:SF37 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 2 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014128.4|UniProtKB=A0A5F8H1F3 A0A5F8H1F3 PTHR21646:SF76 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 32 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of biological quality#GO:0065008;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;regulation of protein stability#GO:0031647;positive regulation of cellular process#GO:0048522;positive regulation of TORC1 signaling#GO:1904263;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000016864.4|UniProtKB=A0A5F8GWI6 A0A5F8GWI6 SEPHS1 PTHR10256:SF2 SELENIDE, WATER DIKINASE ZINCORE COMPONENT SEPHS1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000010813.4|UniProtKB=F7BZP3 F7BZP3 PTHR15746:SF22 RAB11-RELATED RAB11 FAMILY-INTERACTING PROTEIN 1 vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;exocytosis#GO:0006887;secretion by cell#GO:0032940;regulated exocytosis#GO:0045055;transport#GO:0006810 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000015735.2|UniProtKB=A0A5F8GDL1 A0A5F8GDL1 PTHR10093:SF26 IRON-SULFUR CLUSTER ASSEMBLY ENZYME NIFU HOMOLOG IRON-SULFUR CLUSTER ASSEMBLY ENZYME ISCU small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;iron-sulfur cluster binding#GO:0051536;cation binding#GO:0043169;ferrous iron binding#GO:0008198;iron ion binding#GO:0005506 intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000017475.4|UniProtKB=F7FF48 F7FF48 ANOS1 PTHR14131:SF5 ANOSMIN ANOSMIN-1 system development#GO:0048731;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000016868.4|UniProtKB=F6Y2B0 F6Y2B0 EEF1A2 PTHR23115:SF228 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA 2 translation factor activity#GO:0180051;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414 translation factor#PC00223 MONDO|Ensembl=ENSMODG00000014767.4|UniProtKB=F7GGR9 F7GGR9 PTHR24100:SF105 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 2 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 immune system process#GO:0002376;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000043532.1|UniProtKB=A0A5F8GHY5 A0A5F8GHY5 LOC100017609 PTHR10334:SF236 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLIPR1-LIKE PROTEIN 2 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000048733.1|UniProtKB=A0A5F8GDP0 A0A5F8GDP0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000048010.1|UniProtKB=A0A5F8GEA0 A0A5F8GEA0 LOC100020471 PTHR26450:SF77 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015168.4|UniProtKB=F7CES1 F7CES1 SAGE1 PTHR12957:SF22 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED INTEGRATOR COMPLEX SUBUNIT 6-LIKE protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;snRNA processing#GO:0016180;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;integrator complex#GO:0032039;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000001716.4|UniProtKB=A0A5F8GNK7 A0A5F8GNK7 EVC2 PTHR16795:SF14 LIMBIN/ELLIS-VAN CREVELD PROTEIN LIMBIN regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224;cell surface receptor signaling pathway#GO:0007166 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell projection membrane#GO:0031253;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;membrane#GO:0016020;cell periphery#GO:0071944;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 MONDO|Ensembl=ENSMODG00000001421.4|UniProtKB=A0A5F8H473 A0A5F8H473 DHRS7B PTHR44196:SF1 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B PEROXISOMAL REDUCTASE ACTIVATING PPAR-GAMMA cellular anatomical structure#GO:0110165;membrane#GO:0016020 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000021324.4|UniProtKB=H9H7X0 H9H7X0 PPP6R3 PTHR12634:SF12 SIT4 YEAST -ASSOCIATING PROTEIN-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY SUBUNIT 3 protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000025051.2|UniProtKB=F6VRV7 F6VRV7 LOC103102040 PTHR34446:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 10 SMALL INTEGRAL MEMBRANE PROTEIN 10-LIKE PROTEIN 3 MONDO|Ensembl=ENSMODG00000004691.4|UniProtKB=A0A5F8HIY0 A0A5F8HIY0 MPRIP PTHR17271:SF9 PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN MYOSIN PHOSPHATASE RHO-INTERACTING PROTEIN actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000001119.4|UniProtKB=F7A2H1 F7A2H1 PTHR10751:SF1 GUANYLATE BINDING PROTEIN RING FINGER PROTEIN 112 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 heterotrimeric G-protein#PC00117;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000011491.4|UniProtKB=F6V2L6 F6V2L6 KLF1 PTHR23235:SF133 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 1 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000042917.1|UniProtKB=A0A5F8HC16 A0A5F8HC16 ATP5PD PTHR12700:SF12 ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL ATP SYNTHASE PERIPHERAL STALK SUBUNIT D, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;proton channel activity#GO:0015252;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;ligase activity#GO:0016874;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;ribose phosphate biosynthetic process#GO:0046390;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163 membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cytoplasm#GO:0005737;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;transporter complex#GO:1990351;organelle membrane#GO:0031090;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;proton-transporting ATP synthase complex#GO:0045259;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002;transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000001922.5|UniProtKB=F6W0Z6 F6W0Z6 AMPD2 PTHR11359:SF3 AMP DEAMINASE AMP DEAMINASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824 purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;IMP metabolic process#GO:0046040;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;nucleoside phosphate biosynthetic process#GO:1901293;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 deaminase#PC00088 MONDO|Ensembl=ENSMODG00000045409.1|UniProtKB=A0A5F8GM67 A0A5F8GM67 PTHR14693:SF0 RIKEN CDNA 1700018B08 RIKEN CDNA 1700018B08 GENE MONDO|Ensembl=ENSMODG00000010413.3|UniProtKB=A0A5F8H2T5 A0A5F8H2T5 PTHR26453:SF174 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6Q1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002516.6|UniProtKB=F7B970 F7B970 SECISBP2L PTHR13284:SF10 GH01354P SELENOCYSTEINE INSERTION SEQUENCE-BINDING PROTEIN 2-LIKE mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021;mRNA 3'-UTR binding#GO:0003730;protein-containing complex binding#GO:0044877 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000018838.4|UniProtKB=A0A5F8HEN3 A0A5F8HEN3 PTHR10334:SF213 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN 1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000037900.1|UniProtKB=A0A5F8H3A2 A0A5F8H3A2 C1QTNF3 PTHR22923:SF115 CEREBELLIN-RELATED COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 3 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017347.5|UniProtKB=F6WEY3 F6WEY3 KMT2E PTHR46462:SF2 UPSET, ISOFORM A HISTONE READER KMT2E regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Rpd3L-Expanded complex#GO:0070210;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000047090.1|UniProtKB=A0A5F8GMB3 A0A5F8GMB3 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000048661.1|UniProtKB=A0A5F8GJN3 A0A5F8GJN3 PTHR17614:SF13 ZINC FINGER-CONTAINING ZINC FINGER PROTEIN 804A membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000004323.4|UniProtKB=F6X6D9 F6X6D9 CNTN4 PTHR10075:SF63 BASIGIN RELATED CONTACTIN-4 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000045545.1|UniProtKB=K7E1A7 K7E1A7 PTHR46890:SF56 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED OS06G0484800 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000046473.1|UniProtKB=F6WNG8 F6WNG8 PTHR21297:SF0 DNA-DIRECTED RNA POLYMERASE II DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 translation initiation factor binding#GO:0031369;protein binding#GO:0005515;binding#GO:0005488 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 MONDO|Ensembl=ENSMODG00000006145.3|UniProtKB=A0A5F8H2D1 A0A5F8H2D1 VGLL4 PTHR17604:SF1 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 4 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 4 protein binding#GO:0005515;binding#GO:0005488;transcription factor binding#GO:0008134 negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000006001.4|UniProtKB=H9H666 H9H666 INHBC PTHR11848:SF130 TGF-BETA FAMILY INHIBIN BETA C CHAIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000006881.3|UniProtKB=F6PVT7 F6PVT7 GNB1 PTHR19850:SF29 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(T) SUBUNIT BETA-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling receptor complex adaptor activity#GO:0030159;signaling adaptor activity#GO:0035591 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737 G-protein#PC00020;heterotrimeric G-protein#PC00117;protein-binding activity modulator#PC00095 Nicotine pharmacodynamics pathway#P06587>GNB#P06591;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Endogenous cannabinoid signaling#P05730>Gbeta#P05745;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;GABA-B receptor II signaling#P05731>Gbeta#P05755;Enkephalin release#P05913>G-Protein (s)#P05977;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;PI3 kinase pathway#P00048>Gbetagamma#P01188;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Wnt signaling pathway#P00057>GBeta#P01457;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;CCKR signaling map#P06959>Gbeta/gamma#P07197;Enkephalin release#P05913>G-Protein (i)#P05974;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710 MONDO|Ensembl=ENSMODG00000000637.4|UniProtKB=A0A5F8HCK1 A0A5F8HCK1 MATK PTHR24418:SF399 TYROSINE-PROTEIN KINASE MEGAKARYOCYTE-ASSOCIATED TYROSINE-PROTEIN KINASE protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 MONDO|Ensembl=ENSMODG00000000581.4|UniProtKB=F6X3I2 F6X3I2 NIPA1 PTHR12570:SF17 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED MAGNESIUM TRANSPORTER NIPA1 transport#GO:0006810;magnesium ion transport#GO:0015693;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000006371.4|UniProtKB=F7GCT5 F7GCT5 LHX4 PTHR24208:SF116 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX4 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000004381.5|UniProtKB=A0ACM8QK05 A0ACM8QK05 NLGN3 PTHR43903:SF4 NEUROLIGIN NEUROLIGIN-3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 chemical synaptic transmission#GO:0007268;synaptic vesicle endocytosis#GO:0048488;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;postsynapse organization#GO:0099173;modulation of chemical synaptic transmission#GO:0050804;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;anatomical structure development#GO:0048856;cell communication#GO:0007154;localization#GO:0051179;system development#GO:0048731;synaptic vesicle recycling#GO:0036465;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;developmental process#GO:0032502;establishment of localization#GO:0051234;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789;membrane assembly#GO:0071709;endocytosis#GO:0006897;synapse assembly#GO:0007416;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;cell adhesion#GO:0007155;cellular localization#GO:0051641;synaptic signaling#GO:0099536;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;nervous system development#GO:0007399;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000007061.4|UniProtKB=F7DDY5 F7DDY5 PTHR24404:SF96 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025212.2|UniProtKB=F7BF36 F7BF36 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000019148.3|UniProtKB=F7EC75 F7EC75 COX18 PTHR12428:SF70 OXA1 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104 protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;respiratory chain complex IV assembly#GO:0008535;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;establishment of protein localization#GO:0045184;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;protein-containing complex organization#GO:0043933;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 MONDO|Ensembl=ENSMODG00000015245.4|UniProtKB=F6UJG9 F6UJG9 ANO10 PTHR12308:SF40 ANOCTAMIN ANOCTAMIN-10 transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;molecular carrier activity#GO:0140104;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion-gated channel activity#GO:0022839;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;lipid carrier activity#GO:0005319;phospholipid scramblase activity#GO:0017128;ligand-gated monoatomic ion channel activity#GO:0015276;intramembrane lipid carrier activity#GO:0140303;calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267 inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;lipid localization#GO:0010876;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;monoatomic anion transport#GO:0006820;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;lipid transport#GO:0006869;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;macromolecule localization#GO:0033036 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000044624.1|UniProtKB=A0A5F8GB21 A0A5F8GB21 THAP3 PTHR47120:SF1 THAP DOMAIN-CONTAINING PROTEIN 3 THAP DOMAIN-CONTAINING PROTEIN 3 MONDO|Ensembl=ENSMODG00000050155.1|UniProtKB=A0A5F8GA71 A0A5F8GA71 PTHR22574:SF12 FAMILY NOT NAMED GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 5B MONDO|Ensembl=ENSMODG00000002250.5|UniProtKB=A0A5F8GT44 A0A5F8GT44 MAP4K4 PTHR48015:SF2 SERINE/THREONINE-PROTEIN KINASE TAO MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 4 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;intracellular signaling cassette#GO:0141124 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861;Apoptosis signaling pathway#P00006>GCKR#P00311 MONDO|Ensembl=ENSMODG00000001183.4|UniProtKB=F7GHD3 F7GHD3 SFRP2 PTHR11309:SF45 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 2 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089;Wnt-protein binding#GO:0017147;signaling receptor activity#GO:0038023 canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;non-canonical Wnt signaling pathway#GO:0035567 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>sFRP#P01434 MONDO|Ensembl=ENSMODG00000044373.1|UniProtKB=H9H8A1 H9H8A1 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED RETROVIRAL ENVELOPE PROTEIN GP41-LIKE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000937.4|UniProtKB=F7F7X2 F7F7X2 SLC5A10 PTHR11819:SF128 SOLUTE CARRIER FAMILY 5 SODIUM_MANNOSE COTRANSPORTER SLC5A10 symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;sugar transmembrane transporter activity#GO:0051119;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000020760.4|UniProtKB=A0A5F8GYT3 A0A5F8GYT3 SCLT1 PTHR35970:SF1 SODIUM CHANNEL AND CLATHRIN LINKER 1 SODIUM CHANNEL AND CLATHRIN LINKER 1 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000029270.2|UniProtKB=K7E080 K7E080 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000014301.4|UniProtKB=F6W4Q5 F6W4Q5 RNFT1 PTHR15860:SF1 UNCHARACTERIZED RING FINGER-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNFT1 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of ERAD pathway#GO:1904292;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein metabolic process#GO:0051247;regulation of protein catabolic process#GO:0042176;regulation of cellular response to stress#GO:0080135;positive regulation of protein catabolic process#GO:0045732;positive regulation of metabolic process#GO:0009893 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000002048.4|UniProtKB=F6QC13 F6QC13 DENND1C PTHR13196:SF25 DENN DOMAIN-CONTAINING DENN DOMAIN-CONTAINING PROTEIN 1C lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;binding#GO:0005488 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytic recycling#GO:0032456;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000024302.2|UniProtKB=F7EI98 F7EI98 LOC100617479 PTHR48018:SF75 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012024.3|UniProtKB=A0A5F8H847 A0A5F8H847 PTHR13464:SF0 TRANSCRIPTIONAL REGULATOR PROTEIN HCNGP SAP30-BINDING PROTEIN cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000027770.1|UniProtKB=K7DZM0 K7DZM0 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000023179.2|UniProtKB=F7CN57 F7CN57 NUPR2 PTHR17149:SF3 NUCLEAR PROTEIN 1 AND 2 NUCLEAR PROTEIN 2 regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle#GO:0045786;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;negative regulation of cell population proliferation#GO:0008285;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000007621.4|UniProtKB=F7C549 F7C549 GUCY2D PTHR11920:SF228 GUANYLYL CYCLASE RETINAL GUANYLYL CYCLASE 1 molecular transducer activity#GO:0060089;lyase activity#GO:0016829;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824;signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383;peptide receptor activity#GO:0001653 purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;cell communication#GO:0007154;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068 9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;cell projection membrane#GO:0031253;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730 lyase#PC00144;guanylate cyclase#PC00114 CCKR signaling map#P06959>Guanylate cyclase#P07116 MONDO|Ensembl=ENSMODG00000018579.4|UniProtKB=F7FRA3 F7FRA3 COL9A1 PTHR24023:SF918 COLLAGEN ALPHA COLLAGEN ALPHA-1(IX) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;interstitial matrix#GO:0005614;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000000016.3|UniProtKB=F6SIG3 F6SIG3 LOC100027943 PTHR45619:SF44 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT BETA ISOFORM catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein modifying enzyme#PC00260;protein phosphatase#PC00195 p53 pathway feedback loops 2#P04398>PP2A-C#P04659;FGF signaling pathway#P00021>PP2A#P00629;Wnt signaling pathway#P00057>PP2A#P01438;p53 pathway by glucose deprivation#P04397>PP2A-C#P04643;p53 pathway#P00059>PP2A#P04630;EGF receptor signaling pathway#P00018>PP2A#P00547 MONDO|Ensembl=ENSMODG00000020633.4|UniProtKB=F7EN54 F7EN54 SLC10A4 PTHR10361:SF41 SODIUM-BILE ACID COTRANSPORTER SODIUM_BILE ACID COTRANSPORTER 4-RELATED secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic cation transmembrane transporter activity#GO:0008324;bile acid transmembrane transporter activity#GO:0015125;solute:sodium symporter activity#GO:0015370 localization#GO:0051179;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;lipid transport#GO:0006869;macromolecule localization#GO:0033036 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000019562.4|UniProtKB=K7E052 K7E052 PTHR19971:SF24 SIGNAL-REGULATORY PROTEIN BETA IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008375.4|UniProtKB=A0A5F8G5G2 A0A5F8G5G2 BAIAP2L1 PTHR14206:SF4 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 BAR_IMD DOMAIN-CONTAINING ADAPTER PROTEIN 2-LIKE 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of organelle organization#GO:0033043;actin filament bundle organization#GO:0061572;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;regulation of supramolecular fiber organization#GO:1902903;actin filament bundle assembly#GO:0051017;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007668.4|UniProtKB=F7FNP7 F7FNP7 TXNRD3 PTHR48105:SF30 THIOREDOXIN REDUCTASE 1-RELATED-RELATED THIOREDOXIN REDUCTASE 3 antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829 reductase#PC00198;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000005579.4|UniProtKB=F7E513 F7E513 COP1 PTHR44080:SF1 E3 UBIQUITIN-PROTEIN LIGASE COP1 E3 UBIQUITIN-PROTEIN LIGASE COP1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 P53 pathway feedback loops 1#P04392>Cop-1#P04540;P53 pathway feedback loops 1#P04392>Cop-1#G04683 MONDO|Ensembl=ENSMODG00000020388.3|UniProtKB=F7C066 F7C066 KCNMB4 PTHR10258:SF3 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-4 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106 detection of stimulus#GO:0051606;cellular process#GO:0009987;response to chemical#GO:0042221;potassium ion transport#GO:0006813;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;response to metal ion#GO:0010038;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transmission of nerve impulse#GO:0019226;system process#GO:0003008;action potential#GO:0001508;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;metal ion transport#GO:0030001;nervous system process#GO:0050877;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;response to calcium ion#GO:0051592;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000020556.3|UniProtKB=F7AQ16 F7AQ16 UBE2K PTHR24068:SF147 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 K acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Ubiquitin proteasome pathway#P00060>E3#P01490 MONDO|Ensembl=ENSMODG00000019755.3|UniProtKB=F6WN64 F6WN64 ARPC5L PTHR12644:SF2 ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 5-LIKE PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;cell migration#GO:0016477;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 cell cortex#GO:0005938;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Huntington disease#P00029>Arp2/3 complex#P00811 MONDO|Ensembl=ENSMODG00000009434.4|UniProtKB=F7BKP6 F7BKP6 PTHR24299:SF8 CYTOCHROME P450 FAMILY 1 CYTOCHROME P450 1A1 oxidoreductase activity#GO:0016491;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;secondary metabolic process#GO:0019748;lipid catabolic process#GO:0016042;cellular process#GO:0009987;response to chemical#GO:0042221;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;steroid metabolic process#GO:0008202;cellular response to xenobiotic stimulus#GO:0071466;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;estrogen metabolic process#GO:0008210;regulation of biological quality#GO:0065008;steroid catabolic process#GO:0006706;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of hormone levels#GO:0010817;catabolic process#GO:0009056;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000011204.3|UniProtKB=F6SQV8 F6SQV8 LOC100021510 PTHR26450:SF17 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014499.4|UniProtKB=A0A5F8G5D4 A0A5F8G5D4 COPG2 PTHR10261:SF4 COATOMER SUBUNIT GAMMA COATOMER SUBUNIT GAMMA-2 vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport#GO:0006810;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890 endoplasmic reticulum#GO:0005783;Golgi membrane#GO:0000139;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;COPI-coated vesicle#GO:0030137;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;vesicle#GO:0031982;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;organelle#GO:0043226 vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000004661.2|UniProtKB=F6U7K2 F6U7K2 PTHR22802:SF14 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER K binding#GO:0005488;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000028546.2|UniProtKB=K7E638 K7E638 MORC1 PTHR23337:SF6 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 1 MORC FAMILY CW-TYPE ZINC FINGER PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000005110.3|UniProtKB=A0A5F8H4C1 A0A5F8H4C1 PRMT7 PTHR11006:SF4 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 7 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000010837.4|UniProtKB=F6TPD8 F6TPD8 PTHR10338:SF119 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H4 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000025060.2|UniProtKB=F6SB62 F6SB62 PTHR13248:SF4 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2 ELONGIN-B transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of gene silencing by regulatory ncRNA#GO:0060966;negative regulation of metabolic process#GO:0009892;post-transcriptional regulation of gene expression#GO:0010608;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of gene expression#GO:0010628;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;post-transcriptional gene silencing#GO:0016441;protein metabolic process#GO:0019538;positive regulation of biosynthetic process#GO:0009891;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255 intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;cullin-RING ubiquitin ligase complex#GO:0031461;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Cul5-RING ubiquitin ligase complex#GO:0031466;ubiquitin ligase complex#GO:0000151;Cul2-RING ubiquitin ligase complex#GO:0031462;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000004119.4|UniProtKB=F6UWM0 F6UWM0 CLK4 PTHR45646:SF1 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED DUAL SPECIFICITY PROTEIN KINASE CLK4 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000024047.3|UniProtKB=F6YMU4 F6YMU4 GPR65 PTHR24232:SF49 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 65 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000005620.3|UniProtKB=A0A5F8GAJ5 A0A5F8GAJ5 LOC100025458 PTHR31666:SF0 PROTEIN CXORF40A-RELATED PROTEIN EOLA1-RELATED MONDO|Ensembl=ENSMODG00000027466.2|UniProtKB=K7E0V5 K7E0V5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000042083.1|UniProtKB=A0A5F8HDR7 A0A5F8HDR7 HOXB4 PTHR45771:SF3 HOMEOTIC PROTEIN DEFORMED HOMEOBOX PROTEIN HOX-B4 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;skeletal system morphogenesis#GO:0048705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;embryo development#GO:0009790;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;anterior/posterior pattern specification#GO:0009952;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;skeletal system development#GO:0001501;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000042937.1|UniProtKB=A0A5F8GYT2 A0A5F8GYT2 PTHR41694:SF3 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 10 POL PROTEIN-RELATED RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000041862.1|UniProtKB=A0A5F8GD87 A0A5F8GD87 PTHR14759:SF34 STOP PROTEIN MUCIN-LIKE DOMAIN-CONTAINING PROTEIN microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of microtubule-based process#GO:0032886;localization#GO:0051179;cellular localization#GO:0051641 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cis-Golgi network#GO:0005801;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 MONDO|Ensembl=ENSMODG00000000874.4|UniProtKB=A0A5F8GU08 A0A5F8GU08 MAGI3 PTHR10316:SF10 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of protein localization to membrane#GO:1905475 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;adherens junction#GO:0005912;cell junction#GO:0030054;cell-cell junction#GO:0005911;cytoplasm#GO:0005737;synapse#GO:0045202;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000014954.5|UniProtKB=A0A5F8GS40 A0A5F8GS40 TOP2B PTHR10169:SF36 DNA TOPOISOMERASE/GYRASE DNA TOPOISOMERASE 2-BETA ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543 cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;meiosis I#GO:0007127;sister chromatid segregation#GO:0000819;reciprocal homologous recombination#GO:0140527;cell cycle process#GO:0022402;reproductive process#GO:0022414;homologous recombination#GO:0035825;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;sexual reproduction#GO:0019953;reciprocal meiotic recombination#GO:0007131;organelle fission#GO:0048285;organelle organization#GO:0006996;resolution of meiotic recombination intermediates#GO:0000712;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;chromosome organization#GO:0051276 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 DNA replication#P00017>Top#P00530;DNA replication#P00017>DNA Topisomerase#P00536 MONDO|Ensembl=ENSMODG00000009058.4|UniProtKB=F7AF55 F7AF55 SPAG6 PTHR23314:SF3 SPERM-ASSOCIATED ANTIGEN 6 ARMADILLO REPEAT-CONTAINING SPERM-ASSOCIATED ANTIGEN 6 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987;cilium movement#GO:0003341 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;sperm flagellum#GO:0036126;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;sperm principal piece#GO:0097228;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000024383.2|UniProtKB=F6Z4T1 F6Z4T1 PTHR48002:SF134 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000107.4|UniProtKB=F7DMP8 F7DMP8 NAA15 PTHR22767:SF6 N-TERMINAL ACETYLTRANSFERASE-RELATED N-ALPHA-ACETYLTRANSFERASE 15, NATA AUXILIARY SUBUNIT enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000014726.4|UniProtKB=F6ZCV6 F6ZCV6 ADAM17 PTHR45702:SF6 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 17 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 membrane protein proteolysis#GO:0033619;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;membrane protein ectodomain proteolysis#GO:0006509;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;proteolysis#GO:0006508;cell communication#GO:0007154;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;protease#PC00190 Alzheimer disease-presenilin pathway#P00004>TACE#P00147;Notch signaling pathway#P00045>TACE#P01105;Alzheimer disease-amyloid secretase pathway#P00003>TACE#P00092 MONDO|Ensembl=ENSMODG00000018991.4|UniProtKB=A0A5F8HJ02 A0A5F8HJ02 NRG1 PTHR11100:SF7 HEREGULIN-NEUREGULIN FAMILY MEMBER PRO-NEUREGULIN-1, MEMBRANE-BOUND ISOFORM kinase activator activity#GO:0019209;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887 regulation of cellular process#GO:0050794;central nervous system development#GO:0007417;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;peripheral nervous system development#GO:0007422;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;multicellular organismal process#GO:0032501;brain development#GO:0007420;head development#GO:0060322;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;signal transduction#GO:0007165;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 MONDO|Ensembl=ENSMODG00000041022.1|UniProtKB=A0A5F8GQU9 A0A5F8GQU9 PTHR23102:SF19 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-LIKE PROTEIN-RELATED nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000024430.2|UniProtKB=F7F3K5 F7F3K5 PTHR47621:SF1 ZINC FINGER CCCH-TYPE ANTIVIRAL PROTEIN 1-LIKE ZINC FINGER CCCH-TYPE ANTIVIRAL PROTEIN 1-LIKE MONDO|Ensembl=ENSMODG00000015820.4|UniProtKB=A0A5F8HEV5 A0A5F8HEV5 DHX36 PTHR18934:SF274 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT DNA_RNA HELICASE DHX36 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;DNA binding#GO:0003677;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;isomerase activity#GO:0016853;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;DNA helicase activity#GO:0003678;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on DNA#GO:0140097 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000016739.4|UniProtKB=F7BYQ3 F7BYQ3 STUB1-DT PTHR21521:SF0 AMUN, ISOFORM A AMUN, ISOFORM A MONDO|Ensembl=ENSMODG00000017446.3|UniProtKB=F6ZTX8 F6ZTX8 PTHR12002:SF76 CLAUDIN SPERMATOGENESIS ASSOCIATED MULTIPASS TRANSMEMBRANE PROTEIN 2B-RELATED cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216 anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;apical junction complex#GO:0043296;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000011508.4|UniProtKB=F6V0X1 F6V0X1 GCDH PTHR42807:SF1 GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000005300.4|UniProtKB=F7DMM0 F7DMM0 MIDN PTHR23010:SF1 MIDNOLIN MIDNOLIN intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000042978.1|UniProtKB=A0A5F8GGP4 A0A5F8GGP4 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000039164.1|UniProtKB=F6SJ62 F6SJ62 PTHR26453:SF303 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2Y1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016142.3|UniProtKB=F7D7G3 F7D7G3 PTHR26453:SF153 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019877.4|UniProtKB=A0A5F8GRW8 A0A5F8GRW8 MAPK8IP1 PTHR47437:SF3 JNK-INTERACTING PROTEIN 1-LIKE PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 1 molecular adaptor activity#GO:0060090;protein complex scaffold activity#GO:0140378;MAP kinase scaffold activity#GO:0005078;structural molecule activity#GO:0005198;kinase binding#GO:0019900;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;signaling adaptor activity#GO:0035591;protein binding#GO:0005515 MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;JNK cascade#GO:0007254;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000018582.4|UniProtKB=F7FDA8 F7FDA8 TRIM3 PTHR24104:SF21 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 3 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Alzheimer disease-presenilin pathway#P00004>HAC1#P00131 MONDO|Ensembl=ENSMODG00000006819.3|UniProtKB=F6PGF0 F6PGF0 SCNN1B PTHR11690:SF18 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED EPITHELIAL SODIUM CHANNEL SUBUNIT BETA transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transport#GO:0006810 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000050855.1|UniProtKB=A0A5F8G8R6 A0A5F8G8R6 PTHR43963:SF4 CARBONYL REDUCTASE 1-RELATED CARBONYL REDUCTASE (NADPH) oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000021264.4|UniProtKB=F6T305 F6T305 LOC100017577 PTHR14198:SF18 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000018859.3|UniProtKB=A0A5F8H1F1 A0A5F8H1F1 OPN5 PTHR24240:SF0 OPSIN OPSIN-5 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;cellular response to radiation#GO:0071478;signaling#GO:0023052;cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;detection of stimulus#GO:0051606;signal transduction#GO:0007165;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;cellular process#GO:0009987;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000005206.5|UniProtKB=F7A243 F7A243 ZC3H12B PTHR12876:SF27 N4BP1-RELATED RIBONUCLEASE ZC3H12B-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;nuclease activity#GO:0004518;RNA binding#GO:0003723 regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;positive regulation of mRNA catabolic process#GO:0061014;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;positive regulation of macromolecule metabolic process#GO:0010604;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000020906.4|UniProtKB=A0A5F8GVC4 A0A5F8GVC4 MYCBPAP PTHR48421:SF1 MYCBP-ASSOCIATED PROTEIN MYCBP-ASSOCIATED PROTEIN MONDO|Ensembl=ENSMODG00000024210.2|UniProtKB=F6WVX5 F6WVX5 CHCHD5 PTHR47106:SF1 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 5 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 5 cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000018597.3|UniProtKB=F7FCR3 F7FCR3 FOXL2 PTHR11829:SF411 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000009164.4|UniProtKB=F7ADW8 F7ADW8 PPCDC PTHR14359:SF6 HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;lyase activity#GO:0016829;carbohydrate derivative binding#GO:0097367;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166 nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521 catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 Coenzyme A biosynthesis#P02736>Pantothenoylcysteine decarboxylase#P02883;Coenzyme A biosynthesis#P02736>Pantothenate cysteine ligase#P02882 MONDO|Ensembl=ENSMODG00000010777.3|UniProtKB=A0A5F8GXJ0 A0A5F8GXJ0 PTHR11849:SF178 ETS ETS DOMAIN-CONTAINING PROTEIN ELK-1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ELK#P00890;CCKR signaling map#P06959>ELK1#P07146;Toll receptor signaling pathway#P00054>Elk1#P01341;p38 MAPK pathway#P05918>ELK#P06013;Interleukin signaling pathway#P00036>ELK#P00962;PDGF signaling pathway#P00047>ELK#P01140;Ras Pathway#P04393>Elk-1#P04573;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>ELK1#P05934;Gonadotropin-releasing hormone receptor pathway#P06664>ELK1#P06785;Oxidative stress response#P00046>Elk-1#P01136;Parkinson disease#P00049>Elk-1#P01233 MONDO|Ensembl=ENSMODG00000011518.4|UniProtKB=A0A5F8GH53 A0A5F8GH53 DCDC2 PTHR23004:SF5 DOUBLECORTIN DOMAIN CONTAINING 2 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 2 cell motility#GO:0048870;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;system development#GO:0048731;regulation of cell projection assembly#GO:0060491;anatomical structure development#GO:0048856;regulation of organelle assembly#GO:1902115;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cell migration#GO:0016477;multicellular organismal process#GO:0032501;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;regulation of cell projection organization#GO:0031344;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;neuron migration#GO:0001764;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cilium assembly#GO:0060271;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;regulation of plasma membrane bounded cell projection assembly#GO:0120032;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cilium organization#GO:0044782;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;nervous system development#GO:0007399;cellular component assembly#GO:0022607;regulation of cilium assembly#GO:1902017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862;supramolecular fiber#GO:0099512;axoneme#GO:0005930;microtubule#GO:0005874;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815 MONDO|Ensembl=ENSMODG00000024333.2|UniProtKB=F7DG91 F7DG91 LOC100022942 PTHR26452:SF334 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048080.1|UniProtKB=A0A5F8G2N9 A0A5F8G2N9 PTHR24103:SF646 E3 UBIQUITIN-PROTEIN LIGASE TRIM RING FINGER PROTEIN 39 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune system process#GO:0002376;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000049565.1|UniProtKB=A0A5F8H7P8 A0A5F8H7P8 LOC100027380 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014112.4|UniProtKB=F6Y4V2 F6Y4V2 FNIP1 PTHR21634:SF12 RE13835P FOLLICULIN-INTERACTING PROTEIN 1 molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000014419.4|UniProtKB=F7BH65 F7BH65 PTHLH PTHR17223:SF0 PARATHYROID HORMONE-RELATED PARATHYROID HORMONE-RELATED PROTEIN protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;binding#GO:0005488;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;ossification#GO:0001503;regulation of developmental process#GO:0050793;signaling#GO:0023052;cell development#GO:0048468;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of multicellular organismal development#GO:2000026;cell communication#GO:0007154;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;system development#GO:0048731;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;osteoblast differentiation#GO:0001649;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;developmental process#GO:0032502;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell differentiation#GO:0045595 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000039841.1|UniProtKB=A0A5F8GVT4 A0A5F8GVT4 PTHR33166:SF1 GAG_P30 DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000020294.4|UniProtKB=F7BFT6 F7BFT6 MROH2B PTHR23120:SF22 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 2B vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000024292.1|UniProtKB=F7F1D0 F7F1D0 LOC100024791 PTHR48018:SF219 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004269.4|UniProtKB=F6TEV1 F6TEV1 TEK PTHR24416:SF125 TYROSINE-PROTEIN KINASE RECEPTOR ANGIOPOIETIN-1 RECEPTOR phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514;positive regulation of angiogenesis#GO:0045766;positive regulation of cell motility#GO:2000147;signaling#GO:0023052;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;circulatory system development#GO:0072359;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;angiogenesis#GO:0001525;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;epithelial cell proliferation#GO:0050673;endothelial cell proliferation#GO:0001935;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell population proliferation#GO:0008283;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of angiogenesis#GO:0045765;system development#GO:0048731;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;tube development#GO:0035295;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of vasculature development#GO:1901342;positive regulation of locomotion#GO:0040017;positive regulation of MAPK cascade#GO:0043410 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 Angiogenesis#P00005>Tie2#P00247 MONDO|Ensembl=ENSMODG00000051310.1|UniProtKB=A0A5F8H4Y2 A0A5F8H4Y2 FGF9 PTHR11486:SF28 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 9 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;fibroblast growth factor receptor binding#GO:0005104;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 system development#GO:0048731;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of cellular process#GO:0048522;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000003739.4|UniProtKB=F7ECU7 F7ECU7 LOC100020223 PTHR23023:SF74 DIMETHYLANILINE MONOOXYGENASE DIMETHYLANILINE MONOOXYGENASE [N-OXIDE-FORMING] 4 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000011444.4|UniProtKB=F6W1J7 F6W1J7 PTHR46556:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular component organization#GO:0016043;organelle organization#GO:0006996;lysosome localization#GO:0032418;cellular process#GO:0009987;Golgi organization#GO:0007030;regulation of biological process#GO:0050789;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;organelle localization#GO:0051640;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 MONDO|Ensembl=ENSMODG00000003255.2|UniProtKB=A0A5F8H5X9 A0A5F8H5X9 DCXR PTHR44252:SF2 D-ERYTHRULOSE REDUCTASE L-XYLULOSE REDUCTASE alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;glucose metabolic process#GO:0006006;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000050705.1|UniProtKB=A0A5F8GDF9 A0A5F8GDF9 LOC100619224 PTHR26452:SF125 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13A1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000010003.3|UniProtKB=F6URX6 F6URX6 FNTA PTHR11129:SF1 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 acyltransferase#PC00042;transferase#PC00220 MONDO|Ensembl=ENSMODG00000004200.4|UniProtKB=F6XRF2 F6XRF2 ING2 PTHR10333:SF37 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 2 histone reader activity#GO:0140566;histone H3 reader activity#GO:0140006;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;chromatin#GO:0000785;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000004601.4|UniProtKB=F6Y4P9 F6Y4P9 PTHR22662:SF0 TIRAP TOLL_INTERLEUKIN-1 RECEPTOR DOMAIN-CONTAINING ADAPTER PROTEIN Toll receptor signaling pathway#P00054>TIRAP#P01350 MONDO|Ensembl=ENSMODG00000019128.4|UniProtKB=F7EUM5 F7EUM5 AP2B1 PTHR11134:SF9 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-2 COMPLEX SUBUNIT BETA protein binding#GO:0005515;binding#GO:0005488;molecular adaptor activity#GO:0060090;clathrin binding#GO:0030276;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179 vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;AP-1 adaptor complex#GO:0030121;trans-Golgi network transport vesicle#GO:0030140;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane coat#GO:0030117;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endocytic vesicle#GO:0030139;coated vesicle#GO:0030135;coated membrane#GO:0048475;vesicle coat#GO:0030120;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;clathrin vesicle coat#GO:0030125;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated endocytic vesicle#GO:0045334 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000037549.1|UniProtKB=A0A5F8HFF7 A0A5F8HFF7 PTHR48001:SF9 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1J2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015890.5|UniProtKB=F7B358 F7B358 DHX16 PTHR18934:SF83 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16 isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000036589.1|UniProtKB=K7DZH2 K7DZH2 PTHR46890:SF56 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED OS06G0484800 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000037217.1|UniProtKB=A0A5F8GDP3 A0A5F8GDP3 ZNF641 PTHR23226:SF451 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 641 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002968.2|UniProtKB=A0A5F8H873 A0A5F8H873 PTHR15315:SF122 RING FINGER PROTEIN 41, 151 E3 UBIQUITIN-PROTEIN LIGASE NRDP1 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 endoplasmic reticulum tubular network#GO:0071782;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000045634.1|UniProtKB=A0A5F8H149 A0A5F8H149 PINK1 PTHR22972:SF7 SERINE/THREONINE PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE PINK1, MITOCHONDRIAL kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;process utilizing autophagic mechanism#GO:0061919;regulation of programmed cell death#GO:0043067;regulation of organelle organization#GO:0033043;regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;catabolic process#GO:0009056;regulation of mitochondrial fission#GO:0090140;positive regulation of mitochondrial fission#GO:0090141;regulation of developmental process#GO:0050793;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;positive regulation of developmental process#GO:0051094;regulation of anatomical structure morphogenesis#GO:0022603;cellular process#GO:0009987;autophagy#GO:0006914;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000010292.3|UniProtKB=A0A5F8GAY2 A0A5F8GAY2 PTHR22950:SF74 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 5 L-amino acid transmembrane transporter activity#GO:0015179;glycine transmembrane transporter activity#GO:0015187;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 carboxylic acid transmembrane transport#GO:1905039;cellular process#GO:0009987;L-alpha-amino acid transmembrane transport#GO:1902475;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;localization#GO:0051179;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;transport#GO:0006810;glycine transport#GO:0015816 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 amino acid transporter#PC00046;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000002659.3|UniProtKB=F7DI48 F7DI48 C3orf70 PTHR31785:SF2 UPF0524 PROTEIN C3ORF70 UPF0524 PROTEIN C3ORF70 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;rhythmic process#GO:0048511;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;circadian rhythm#GO:0007623;system development#GO:0048731;multicellular organismal process#GO:0032501;nervous system development#GO:0007399 MONDO|Ensembl=ENSMODG00000042214.1|UniProtKB=A0A5F8GSV8 A0A5F8GSV8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000043571.1|UniProtKB=A0A5F8H981 A0A5F8H981 SLCO1C1 PTHR11388:SF99 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1C1 active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 transporter#PC00227 MONDO|Ensembl=ENSMODG00000029118.2|UniProtKB=K7E202 K7E202 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001557.3|UniProtKB=F7BX84 F7BX84 RBM39 PTHR48036:SF10 SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED RNA-BINDING PROTEIN 39 protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000000474.3|UniProtKB=F6UAR4 F6UAR4 PTHR10003:SF77 SUPEROXIDE DISMUTASE CU-ZN -RELATED EXTRACELLULAR SUPEROXIDE DISMUTASE [CU-ZN] catalytic activity#GO:0003824;copper ion binding#GO:0005507;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 cellular response to oxygen-containing compound#GO:1901701;cellular oxidant detoxification#GO:0098869;cellular process#GO:0009987;response to stress#GO:0006950;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;superoxide metabolic process#GO:0006801;cellular response to chemical stress#GO:0062197;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000015278.3|UniProtKB=F6TLW8 F6TLW8 SULT6B1 PTHR11783:SF55 SULFOTRANSFERASE SULT SULFOTRANSFERASE 6B1 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000006240.3|UniProtKB=F7FS02 F7FS02 PTHR18843:SF2 TORSIN-1A-INTERACTING PROTEIN TORSIN-1A-INTERACTING PROTEIN 2 endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000004711.2|UniProtKB=A0A0B4J1D8 A0A0B4J1D8 LAMP5 PTHR11506:SF45 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 5 establishment of localization#GO:0051234;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;establishment of protein localization#GO:0045184 cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;late endosome membrane#GO:0031902;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000017134.4|UniProtKB=A0A5F8GS73 A0A5F8GS73 PPEF1 PTHR45668:SF1 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE WITH EF-HANDS 1 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000009004.4|UniProtKB=F7BQ56 F7BQ56 ENTHD1 PTHR12276:SF57 EPSIN/ENT-RELATED ENTH DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987 clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle coat#GO:0030120;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;clathrin-coated vesicle membrane#GO:0030665;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle#GO:0030136;clathrin vesicle coat#GO:0030125 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000000652.4|UniProtKB=F6SUA7 F6SUA7 UBE2T PTHR24068:SF159 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 T aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 response to stress#GO:0006950;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;response to stimulus#GO:0050896;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000045920.1|UniProtKB=A0A5F8GMX9 A0A5F8GMX9 DTD2 PTHR10472:SF1 D-TYROSYL-TRNA TYR DEACYLASE D-AMINOACYL-TRNA DEACYLASE 2 catalytic activity, acting on RNA#GO:0140098;deacylase activity#GO:0160215;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;carboxylic ester hydrolase activity#GO:0052689 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 MONDO|Ensembl=ENSMODG00000005575.3|UniProtKB=F7E536 F7E536 TSNAXIP1 PTHR16306:SF0 TRANSLIN-ASSOCIATED FACTOR X-INTERACTING PROTEIN 1 TRANSLIN-ASSOCIATED FACTOR X-INTERACTING PROTEIN 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000005001.3|UniProtKB=F7GGU6 F7GGU6 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED RETROVIRAL ENVELOPE PROTEIN GP41-LIKE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000028848.2|UniProtKB=K7DZE0 K7DZE0 LOC100011551 PTHR10907:SF64 REGUCALCIN REGUCALCIN hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 esterase#PC00097;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000050100.1|UniProtKB=A0A5F8H446 A0A5F8H446 PTHR23226:SF454 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 665-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009604.5|UniProtKB=F7A8K3 F7A8K3 HOXD1 PTHR45946:SF1 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN HOX-D1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000016848.4|UniProtKB=F6WQW1 F6WQW1 ARFGAP1 PTHR46395:SF1 ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of transport#GO:0051049;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of endocytosis#GO:0030100;regulation of intracellular signal transduction#GO:1902531 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 GTPase-activating protein#PC00257;G-protein modulator#PC00022 Integrin signalling pathway#P00034>ASAP1#P00909 MONDO|Ensembl=ENSMODG00000004192.5|UniProtKB=F6Y989 F6Y989 CDKN2AIP PTHR16148:SF11 NF-KAPPA-B-REPRESSING FACTOR-RELATED CDKN2A-INTERACTING PROTEIN regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;response to stress#GO:0006950;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000020615.3|UniProtKB=F6ZB23 F6ZB23 TBCK PTHR22957:SF168 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000045235.1|UniProtKB=A0A5F8GAG6 A0A5F8GAG6 PTHR20951:SF2 C13ORF1 PROTEIN-RELATED SPRY DOMAIN-CONTAINING PROTEIN 7 MONDO|Ensembl=ENSMODG00000002238.3|UniProtKB=F7DFS1 F7DFS1 PTHR42918:SF16 LYSYL-TRNA SYNTHETASE LYSINE--TRNA LIGASE nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity#GO:0016874;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098;binding#GO:0005488;nucleic acid binding#GO:0003676;adenylyltransferase activity#GO:0070566;RNA binding#GO:0003723;tRNA binding#GO:0000049;catalytic activity, acting on a tRNA#GO:0140101 nucleobase-containing small molecule metabolic process#GO:0055086;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;immune effector process#GO:0002252;leukocyte activation involved in immune response#GO:0002366;positive regulation of leukocyte activation#GO:0002696;gene expression#GO:0010467;myeloid leukocyte activation#GO:0002274;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;tRNA aminoacylation for protein translation#GO:0006418;regulation of macrophage activation#GO:0043030;RNA metabolic process#GO:0016070;nucleotide metabolic process#GO:0009117;cell activation involved in immune response#GO:0002263;nucleotide biosynthetic process#GO:0009165;immune system process#GO:0002376;protein biosynthetic process#GO:0160307;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;phosphorus metabolic process#GO:0006793;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;nucleoside phosphate biosynthetic process#GO:1901293;multicellular organismal process#GO:0032501;amino acid metabolic process#GO:0006520;positive regulation of cell activation#GO:0050867;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;tRNA aminoacylation#GO:0043039;organophosphate metabolic process#GO:0019637;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;translation#GO:0006412;cell activation#GO:0001775;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;nucleoside phosphate metabolic process#GO:0006753;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;leukocyte activation#GO:0045321 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000048390.1|UniProtKB=A0A5F8H8X0 A0A5F8H8X0 PDCL PTHR46052:SF4 PHOSDUCIN-LIKE PROTEIN PHOSDUCIN-LIKE PROTEIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000011094.4|UniProtKB=F7FVN5 F7FVN5 LOC100019741 PTHR14224:SF9 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 14 MONDO|Ensembl=ENSMODG00000024264.1|UniProtKB=F6Z632 F6Z632 LOC100017346 PTHR48018:SF55 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017574.3|UniProtKB=F7BS51 F7BS51 INPP5E PTHR46625:SF1 72 KDA INOSITOL POLYPHOSPHATE 5-PHOSPHATASE PHOSPHATIDYLINOSITOL POLYPHOSPHATE 5-PHOSPHATASE TYPE IV hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629 nucleus#GO:0005634;endomembrane system#GO:0012505;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;Golgi apparatus#GO:0005794;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000016871.2|UniProtKB=F6Y282 F6Y282 PTHR14572:SF0 PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR MONDO|Ensembl=ENSMODG00000039571.1|UniProtKB=A0A5F8GSN5 A0A5F8GSN5 PTHR13723:SF20 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 13 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000019037.4|UniProtKB=F7BKV5 F7BKV5 UBR2 PTHR21497:SF28 UBIQUITIN LIGASE E3 ALPHA-RELATED E3 UBIQUITIN-PROTEIN LIGASE UBR2 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000047622.1|UniProtKB=A0A5F8HFT8 A0A5F8HFT8 LOC100023494 PTHR26450:SF24 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR FAMILY 52 SUBFAMILY AC MEMBER 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004672.4|UniProtKB=F6U725 F6U725 DUSP10 PTHR10159:SF299 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 10 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;regulation of JNK cascade#GO:0046328;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 p38 MAPK pathway#P05918>MKP5#P05921;Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000014127.3|UniProtKB=F6XLJ9 F6XLJ9 BPGM PTHR11931:SF11 PHOSPHOGLYCERATE MUTASE BISPHOSPHOGLYCERATE MUTASE intramolecular phosphotransferase activity#GO:0016868;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853;phosphoglycerate mutase activity#GO:0004619 monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 isomerase#PC00135;mutase#PC00160 Glycolysis#P00024>Phosphoglyceromutase#P00680 MONDO|Ensembl=ENSMODG00000040033.1|UniProtKB=A0A5F8GZU3 A0A5F8GZU3 PTHR13160:SF4 OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000006385.4|UniProtKB=A0A5F8GSE4 A0A5F8GSE4 CES3 PTHR11559:SF416 CARBOXYLESTERASE CARBOXYLESTERASE 3 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 esterase#PC00097 MONDO|Ensembl=ENSMODG00000007968.4|UniProtKB=A0A5F8GFE0 A0A5F8GFE0 SLU7 PTHR12942:SF2 STEP II SPLICING FACTOR SLU7 PRE-MRNA-SPLICING FACTOR SLU7 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;pre-mRNA binding#GO:0036002 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000020079.4|UniProtKB=F7GI61 F7GI61 PCSK1 PTHR42884:SF39 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED NEUROENDOCRINE CONVERTASE 1 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;proteolysis#GO:0006508;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;biological regulation#GO:0065007;gene expression#GO:0010467;protein maturation#GO:0051604;hormone metabolic process#GO:0042445;protein processing#GO:0016485;peptide hormone processing#GO:0016486;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 neuron projection#GO:0043005;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 serine protease#PC00203 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Endothelin signaling pathway#P00019>furin#P00575;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 MONDO|Ensembl=ENSMODG00000014725.3|UniProtKB=F6ZD39 F6ZD39 KLHL11 PTHR24412:SF420 KELCH PROTEIN KELCH-LIKE PROTEIN 11 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000002325.4|UniProtKB=F6YCQ1 F6YCQ1 VSTM4 PTHR12207:SF8 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 4 cellular anatomical structure#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000020267.4|UniProtKB=F7C1B1 F7C1B1 PTHR45689:SF3 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 1 transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079 monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987 dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;transmembrane transporter complex#GO:1902495;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000017411.3|UniProtKB=F7AJI1 F7AJI1 SYNC PTHR47147:SF1 SYNCOILIN SYNCOILIN cellular process#GO:0009987;intermediate filament-based process#GO:0045103 synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane#GO:0016020;cytosol#GO:0005829;Z disc#GO:0030018;cell periphery#GO:0071944;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;I band#GO:0031674;membraneless organelle#GO:0043228;neuromuscular junction#GO:0031594;sarcolemma#GO:0042383;sarcomere#GO:0030017;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000017106.3|UniProtKB=A0A5F8GJQ5 A0A5F8GJQ5 PTHR10791:SF30 RAG1-ACTIVATING PROTEIN 1 SUGAR TRANSPORTER SWEET1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 carbohydrate transport#GO:0008643;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000006354.4|UniProtKB=F6ZRK4 F6ZRK4 IGSF22 PTHR13817:SF153 TITIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 22 structural molecule activity#GO:0005198 striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;actomyosin structure organization#GO:0031032;cell development#GO:0048468;muscle cell development#GO:0055001;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 M band#GO:0031430;intracellular organelle#GO:0043229;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;A band#GO:0031672;contractile muscle fiber#GO:0043292;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000014685.4|UniProtKB=A0A5F8HFZ3 A0A5F8HFZ3 ASAP2 PTHR45854:SF4 ASAP FAMILY MEMBER ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000012523.3|UniProtKB=F6PZX9 F6PZX9 CHDH PTHR11552:SF231 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE CHOLINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000039278.1|UniProtKB=F6SJU3 F6SJU3 LOC103097644 PTHR24379:SF131 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 712 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000001223.4|UniProtKB=F7G7K3 F7G7K3 RAB28 PTHR24073:SF572 DRAB5-RELATED RAS-RELATED PROTEIN RAB-28 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000011078.3|UniProtKB=A0A5F8H3L6 A0A5F8H3L6 PTHR11851:SF226 METALLOPROTEASE CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle lumen#GO:0043233;respiratory chain complex III#GO:0045275;transporter complex#GO:1990351;endopeptidase complex#GO:1905369;peptidase complex#GO:1905368;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000002000.4|UniProtKB=F6RHI7 F6RHI7 CPEB1 PTHR12566:SF9 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 1 translation factor activity#GO:0180051;mRNA 3'-UTR binding#GO:0003730;translation regulator activity#GO:0045182;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021 negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of translation#GO:0017148;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;neuron projection#GO:0043005;nucleus#GO:0005634;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000042224.1|UniProtKB=A0A5F8HLZ1 A0A5F8HLZ1 VN2R553 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045471.1|UniProtKB=A0A5F8GA92 A0A5F8GA92 LOC100028622 PTHR48002:SF153 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011792.3|UniProtKB=F7CBV5 F7CBV5 STING1 PTHR34339:SF1 STIMULATOR OF INTERFERON GENES PROTEIN STIMULATOR OF INTERFERON GENES PROTEIN ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;guanyl ribonucleotide binding#GO:0032561 cellular process#GO:0009987;autophagosome organization#GO:1905037;defense response to symbiont#GO:0140546;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;response to stimulus#GO:0050896;immune system process#GO:0002376;process utilizing autophagic mechanism#GO:0061919;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;defense response#GO:0006952;regulation of catabolic process#GO:0009894;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of catabolic process#GO:0009896;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;positive regulation of type I interferon production#GO:0032481;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;response to virus#GO:0009615;autophagy#GO:0006914;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;metabolic process#GO:0008152;regulation of macroautophagy#GO:0016241;positive regulation of response to external stimulus#GO:0032103;cellular component organization#GO:0016043;defense response to virus#GO:0051607;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of macroautophagy#GO:0016239;positive regulation of metabolic process#GO:0009893;positive regulation of innate immune response#GO:0045089;reticulophagy#GO:0061709;regulation of macromolecule biosynthetic process#GO:0010556;activation of innate immune response#GO:0002218;macroautophagy#GO:0016236;response to other organism#GO:0051707;regulation of response to stress#GO:0080134;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;response to external stimulus#GO:0009605;regulation of response to biotic stimulus#GO:0002831;response to external biotic stimulus#GO:0043207;positive regulation of cytokine production#GO:0001819;catabolic process#GO:0009056;organelle assembly#GO:0070925;vacuole organization#GO:0007033;positive regulation of biosynthetic process#GO:0009891 organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;autophagosome#GO:0005776;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000018560.4|UniProtKB=F7G273 F7G273 OGFRL1 PTHR14015:SF0 OPIOID GROWTH FACTOR RECEPTOR OGFR ZETA-TYPE OPIOID RECEPTOR OPIOID GROWTH FACTOR RECEPTOR-LIKE PROTEIN 1 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010600.4|UniProtKB=F7DT27 F7DT27 HIC1 PTHR24394:SF16 ZINC FINGER PROTEIN HYPERMETHYLATED IN CANCER 1 PROTEIN DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016230.4|UniProtKB=A0A5F8G868 A0A5F8G868 CTLA4 PTHR11494:SF8 CYTOTOXIC T-LYMPHOCYTE PROTEIN CYTOTOXIC T-LYMPHOCYTE PROTEIN 4 negative regulation of T cell activation#GO:0050868;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of hemopoiesis#GO:1903706;cellular response to stimulus#GO:0051716;negative regulation of multicellular organismal process#GO:0051241;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of developmental process#GO:0050793;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;T cell receptor signaling pathway#GO:0050852;negative regulation of cell activation#GO:0050866;regulation of cell development#GO:0060284;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;negative regulation of cell adhesion#GO:0007162;immune system process#GO:0002376;regulation of multicellular organismal development#GO:2000026;immune response-regulating signaling pathway#GO:0002764;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;B cell receptor signaling pathway#GO:0050853;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;regulation of T cell activation#GO:0050863;antigen receptor-mediated signaling pathway#GO:0050851;negative regulation of cell-cell adhesion#GO:0022408 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000015547.4|UniProtKB=F6SKK6 F6SKK6 LIX1 PTHR31139:SF5 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG PROTEIN LIMB EXPRESSION 1 HOMOLOG cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000004032.3|UniProtKB=F7CMG3 F7CMG3 PTHR43503:SF4 MCG48959-RELATED PEROXIREDOXIN-6 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601 cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 peroxidase#PC00180;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000019649.4|UniProtKB=F7DD10 F7DD10 RAB14 PTHR24073:SF185 DRAB5-RELATED RAS-RELATED PROTEIN RAB-14 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;lytic vacuole organization#GO:0080171;intracellular protein transport#GO:0006886;transport#GO:0006810;phagolysosome assembly#GO:0001845;intracellular transport#GO:0046907;phagocytosis#GO:0006909;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;lysosome organization#GO:0007040;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;post-Golgi vesicle-mediated transport#GO:0006892;vacuole organization#GO:0007033;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;organelle assembly#GO:0070925;cytosolic transport#GO:0016482;endocytosis#GO:0006897;Golgi to endosome transport#GO:0006895;cellular component organization#GO:0016043 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000017821.4|UniProtKB=F6ZXK1 F6ZXK1 SLCO1A2 PTHR11388:SF16 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1A2 active transmembrane transporter activity#GO:0022804;bile acid transmembrane transporter activity#GO:0015125;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 bile acid and bile salt transport#GO:0015721;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;macromolecule localization#GO:0033036;lipid transport#GO:0006869 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178 transporter#PC00227 MONDO|Ensembl=ENSMODG00000028030.2|UniProtKB=K7DYW9 K7DYW9 DYDC2 PTHR23356:SF16 DPY30-RELATED DPY30 DOMAIN-CONTAINING PROTEIN 1 organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;membraneless organelle#GO:0043228;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000013600.4|UniProtKB=F6VVM2 F6VVM2 ORAI2 PTHR31501:SF5 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 PROTEIN ORAI-2 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000003871.4|UniProtKB=A0A5F8GLL9 A0A5F8GLL9 ZDHHC15 PTHR22883:SF270 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC15 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;developmental maturation#GO:0021700;developmental process#GO:0032502;protein targeting to membrane#GO:0006612;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188;establishment of localization#GO:0051234;cellular component organization#GO:0016043;protein targeting#GO:0006605;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000024262.1|UniProtKB=F6ZU19 F6ZU19 LOC100013624 PTHR13396:SF4 NEDD4 FAMILY INTERACTING PROTEIN 1/2 NEDD4 FAMILY-INTERACTING PROTEIN 2 regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;primary metabolic process#GO:0044238;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of protein modification process#GO:0031399;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of protein ubiquitination#GO:0031396;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000018134.4|UniProtKB=F7DGP2 F7DGP2 FHL5 PTHR24205:SF7 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS PROTEIN 5 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000005449.3|UniProtKB=A0A5F8G949 A0A5F8G949 PSKH1 PTHR24347:SF254 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE H1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000039904.1|UniProtKB=A0A5F8GEU1 A0A5F8GEU1 PTHR12840:SF1 NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000045731.1|UniProtKB=A0A5F8HEC6 A0A5F8HEC6 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000041095.1|UniProtKB=F6Q969 F6Q969 PTHR26450:SF11 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013731.4|UniProtKB=F6XQJ4 F6XQJ4 ALKBH5 PTHR32074:SF2 RNA DEMETHYLASE ALKBH5 RNA DEMETHYLASE ALKBH5 dioxygenase activity#GO:0051213;demethylase activity#GO:0032451;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000016164.4|UniProtKB=F7G8S3 F7G8S3 TELO2 PTHR15830:SF10 TELOMERE LENGTH REGULATION PROTEIN TEL2 FAMILY MEMBER TELOMERE LENGTH REGULATION PROTEIN TEL2 HOMOLOG DNA binding#GO:0003677;protein binding#GO:0005515;Hsp90 protein binding#GO:0051879;binding#GO:0005488;nucleic acid binding#GO:0003676;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;heat shock protein binding#GO:0031072 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000010200.4|UniProtKB=F6SBP2 F6SBP2 ARL2 PTHR45697:SF2 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2 small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000028318.2|UniProtKB=K7E3K0 K7E3K0 S1PR2 PTHR22750:SF17 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 2 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;bioactive lipid receptor activity#GO:0045125 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000015038.4|UniProtKB=F7G5E4 F7G5E4 PTHR14076:SF9 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RECEPTOR ACTIVITY-MODIFYING PROTEIN 2 coreceptor activity#GO:0015026;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 angiogenesis#GO:0001525;cellular localization#GO:0051641;monoatomic ion transport#GO:0006811;protein transport#GO:0015031;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;endocytosis#GO:0006897;cellular response to hormone stimulus#GO:0032870;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;blood vessel morphogenesis#GO:0048514;protein localization to membrane#GO:0072657;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;import into cell#GO:0098657;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;calcium ion transport#GO:0006816;vasculature development#GO:0001944;protein localization to cell periphery#GO:1990778;vesicle-mediated transport#GO:0016192;response to chemical#GO:0042221;response to hormone#GO:0009725;receptor internalization#GO:0031623;cellular process#GO:0009987;establishment of protein localization#GO:0045184;signal transduction#GO:0007165;anatomical structure development#GO:0048856;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;system development#GO:0048731;localization within membrane#GO:0051668;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;protein localization to plasma membrane#GO:0072659;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;developmental process#GO:0032502;multicellular organismal process#GO:0032501;tube development#GO:0035295;biological regulation#GO:0065007;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000042579.1|UniProtKB=A0A5F8GM18 A0A5F8GM18 PTHR19433:SF114 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 20-RELATED response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000039118.1|UniProtKB=A0A5F8HF18 A0A5F8HF18 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000044247.1|UniProtKB=A0A5F8HIN3 A0A5F8HIN3 EFNB3 PTHR11304:SF34 EPHRIN EPHRIN-B3 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon development#GO:0061564;axon guidance#GO:0007411;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902 synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000041722.1|UniProtKB=A0A5F8GL31 A0A5F8GL31 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000025386.1|UniProtKB=F6YJK4 F6YJK4 SMCR8 PTHR31334:SF1 SMITH-MAGENIS SYNDROME REGION GENE 8 PROTEIN GUANINE NUCLEOTIDE EXCHANGE PROTEIN SMCR8 intracellular protein-containing complex#GO:0140535;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000004662.4|UniProtKB=F6U7G0 F6U7G0 DOT1L PTHR21451:SF0 HISTONE H3 METHYLTRANSFERASE HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;heterochromatin organization#GO:0070828;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;cellular component assembly#GO:0022607;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;constitutive heterochromatin formation#GO:0140719;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;DNA integrity checkpoint signaling#GO:0031570;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;DNA damage checkpoint signaling#GO:0000077;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;heterochromatin formation#GO:0031507;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000004279.3|UniProtKB=F6TEJ3 F6TEJ3 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000051332.1|UniProtKB=A0A5F8HK99 A0A5F8HK99 PTHR26453:SF0 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13D1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045961.1|UniProtKB=A0A5F8G7N3 A0A5F8G7N3 PTHR48520:SF1 SECRETED PROTEIN SECRETED PROTEIN MONDO|Ensembl=ENSMODG00000021399.4|UniProtKB=F7CVI6 F7CVI6 CD226 PTHR47011:SF1 CD226 ANTIGEN CD226 ANTIGEN protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;positive regulation of adaptive immune response#GO:0002821;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune effector process#GO:0002697;positive regulation of signaling#GO:0023056;positive regulation of lymphocyte mediated immunity#GO:0002708;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;positive regulation of immune effector process#GO:0002699;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of leukocyte mediated immunity#GO:0002705 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 MONDO|Ensembl=ENSMODG00000012129.4|UniProtKB=A0A5F8GME2 A0A5F8GME2 UCHL5 PTHR10589:SF51 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of chromosome organization#GO:0033044 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000012257.4|UniProtKB=F6YGK6 F6YGK6 HSPA4L PTHR45639:SF5 HSC70CB, ISOFORM G-RELATED HEAT SHOCK 70 KDA PROTEIN 4L enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072;Hsp70 family chaperone#PC00027 MONDO|Ensembl=ENSMODG00000018719.4|UniProtKB=A0A5F8G4N7 A0A5F8G4N7 BIN1 PTHR46514:SF4 AMPHIPHYSIN MYC BOX-DEPENDENT-INTERACTING PROTEIN 1 protein binding#GO:0005515;lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092 synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;presynapse#GO:0098793;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000023868.3|UniProtKB=F6YUA3 F6YUA3 TMEM220 PTHR34262:SF1 TRANSMEMBRANE PROTEIN 220 TRANSMEMBRANE PROTEIN 220 MONDO|Ensembl=ENSMODG00000004033.4|UniProtKB=F7CMF7 F7CMF7 MXD4 PTHR11969:SF4 MAX DIMERIZATION, MAD MAX DIMERIZATION PROTEIN 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000020417.5|UniProtKB=A0A5F8H208 A0A5F8H208 TBC1D15 PTHR11473:SF16 AROMATIC AMINO ACID HYDROXYLASE TRYPTOPHAN 5-HYDROXYLASE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 metabolic process#GO:0008152;serotonin metabolic process#GO:0042428;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958;phenol-containing compound biosynthetic process#GO:0046189;biosynthetic process#GO:0009058;serotonin biosynthetic process#GO:0042427 neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 5-Hydroxytryptamine biosynthesis#P04371>Tryptophan hydroxylase#P04399 MONDO|Ensembl=ENSMODG00000006205.4|UniProtKB=F6ZTF4 F6ZTF4 SAMM50 PTHR12815:SF18 SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER SORTING AND ASSEMBLY MACHINERY COMPONENT 50 HOMOLOG cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;mitochondrial membrane organization#GO:0007006;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;protein insertion into mitochondrial outer membrane#GO:0045040;cellular localization#GO:0051641;localization#GO:0051179 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane translocase complex#GO:0005742;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740 MONDO|Ensembl=ENSMODG00000009055.4|UniProtKB=F7AF77 F7AF77 PDHA1 PTHR11516:SF60 PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;acetyl-CoA metabolic process#GO:0006084;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;pyruvate metabolic process#GO:0006090;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521 membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;transferase complex#GO:1990234;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;oxidoreductase complex#GO:1990204 oxidoreductase#PC00176;dehydrogenase#PC00092 Pyruvate metabolism#P02772>Pyruvate Dehydrogenase#P03133 MONDO|Ensembl=ENSMODG00000051602.1|UniProtKB=A0A5F8GHY9 A0A5F8GHY9 NMNAT2 PTHR12039:SF18 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE_NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 2 adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;pyridine-containing compound metabolic process#GO:0072524;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 nucleotidyltransferase#PC00174;transferase#PC00220 MONDO|Ensembl=ENSMODG00000024848.2|UniProtKB=F7EBU9 F7EBU9 PTHR14339:SF11 VASCULIN VASCULIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000006447.3|UniProtKB=F7FTV2 F7FTV2 XPR1 PTHR10783:SF141 XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED SOLUTE CARRIER FAMILY 53 MEMBER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;phosphate transmembrane transporter activity#GO:0005315;efflux transmembrane transporter activity#GO:0015562;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;export from cell#GO:0140352;homeostatic process#GO:0042592;phosphate ion transport#GO:0006817;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;inorganic anion transport#GO:0015698;cellular homeostasis#GO:0019725 Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000024719.2|UniProtKB=F7EYP6 F7EYP6 PID1 PTHR16265:SF1 PTB-CONTAINING, CUBILIN AND LRP1-INTERACTING PROTEIN PTB-CONTAINING, CUBILIN AND LRP1-INTERACTING PROTEIN regulation of metabolic process#GO:0019222;regulation of transmembrane transport#GO:0034762;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of reactive oxygen species metabolic process#GO:2000377;regulation of transport#GO:0051049;regulation of localization#GO:0032879 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000015965.4|UniProtKB=A0A5F8HC66 A0A5F8HC66 SCARA3 PTHR24024:SF45 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A SCAVENGER RECEPTOR CLASS A MEMBER 3 pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of endocytosis#GO:0030100;immune effector process#GO:0002252;chemical homeostasis#GO:0048878;humoral immune response#GO:0006959;regulation of transport#GO:0051049;regulation of localization#GO:0032879;activation of immune response#GO:0002253;positive regulation of transport#GO:0051050;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;defense response to other organism#GO:0098542;positive regulation of cellular component organization#GO:0051130;immune system process#GO:0002376;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;multicellular organismal-level homeostasis#GO:0048871;defense response#GO:0006952;innate immune response#GO:0045087;complement activation#GO:0006956;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;positive regulation of endocytosis#GO:0045807;multicellular organismal process#GO:0032501;regulation of immune response#GO:0050776;homeostatic process#GO:0042592;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 surfactant#PC00212;structural protein#PC00211 MONDO|Ensembl=ENSMODG00000009486.4|UniProtKB=F7FN99 F7FN99 ENO4 PTHR11902:SF30 ENOLASE ENOLASE 4 catalytic activity#GO:0003824;phosphopyruvate hydratase activity#GO:0004634;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496 cytosol#GO:0005829;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 lyase#PC00144;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000015813.3|UniProtKB=F7FE49 F7FE49 TCF19 PTHR15464:SF1 TRANSCRIPTION FACTOR 19 TRANSCRIPTION FACTOR 19 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000019436.4|UniProtKB=A0A5F8HCA6 A0A5F8HCA6 PARP8 PTHR21328:SF3 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP8 protein kinase activator activity#GO:0030295;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;kinase activator activity#GO:0019209;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;transferase activity#GO:0016740;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme binding#GO:0019899;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;kinase binding#GO:0019900;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;enzyme regulator activity#GO:0030234 response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;cellular process#GO:0009987;signal transduction#GO:0007165 nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum tubular network#GO:0071782;nucleus#GO:0005634;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 MONDO|Ensembl=ENSMODG00000020675.4|UniProtKB=F7DL98 F7DL98 BANK1 PTHR16267:SF13 BANK1/PIK3AP1 FAMILY MEMBER B-CELL SCAFFOLD PROTEIN WITH ANKYRIN REPEATS protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102 negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;immune system process#GO:0002376;regulation of signaling#GO:0023051;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;B cell activation#GO:0042113;lymphocyte activation#GO:0046649;negative regulation of leukocyte activation#GO:0002695;regulation of multicellular organismal process#GO:0051239;negative regulation of signal transduction#GO:0009968;negative regulation of lymphocyte activation#GO:0051250;regulation of B cell activation#GO:0050864;cellular process#GO:0009987;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;cell activation#GO:0001775;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646;leukocyte activation#GO:0045321;negative regulation of multicellular organismal process#GO:0051241;negative regulation of cell activation#GO:0050866;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 MONDO|Ensembl=ENSMODG00000015039.4|UniProtKB=F7G5D4 F7G5D4 USE1 PTHR13050:SF7 USE1-LIKE PROTEIN VESICLE TRANSPORT PROTEIN USE1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport#GO:0006810;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000043268.1|UniProtKB=A0A5F8H8Q5 A0A5F8H8Q5 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017776.3|UniProtKB=F7DJD6 F7DJD6 CKMT1A PTHR11547:SF24 ARGININE OR CREATINE KINASE CREATINE KINASE U-TYPE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775 organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;modified amino acid metabolic process#GO:0006575;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 amino acid kinase#PC00045;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000027377.2|UniProtKB=K7DZH3 K7DZH3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013489.4|UniProtKB=F7F8R2 F7F8R2 MARK3 PTHR24346:SF1 MAP/MICROTUBULE AFFINITY-REGULATING KINASE MAP_MICROTUBULE AFFINITY-REGULATING KINASE 3 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000027719.2|UniProtKB=K7E1G7 K7E1G7 BTBD18 PTHR47639:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 18 BTB_POZ DOMAIN-CONTAINING PROTEIN 18 male gamete generation#GO:0048232;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;spermatogenesis#GO:0007283;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;DNA-templated transcription#GO:0006351;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;gene expression#GO:0010467;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000015226.3|UniProtKB=F6V3R4 F6V3R4 RAB35 PTHR47977:SF76 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-35 guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;transport#GO:0006810;localization within membrane#GO:0051668;intracellular transport#GO:0046907;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000007546.5|UniProtKB=A0A5F8GTW9 A0A5F8GTW9 XIRP2 PTHR22591:SF1 XIN XIN ACTIN-BINDING REPEAT-CONTAINING PROTEIN 2 cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 actin cytoskeleton#GO:0015629;actomyosin#GO:0042641;organelle#GO:0043226;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;intracellular membraneless organelle#GO:0043232;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856;stress fiber#GO:0001725;intracellular organelle#GO:0043229;cell junction#GO:0030054;actin filament bundle#GO:0032432;membraneless organelle#GO:0043228;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000012003.4|UniProtKB=F7AML6 F7AML6 P2RX4 PTHR10125:SF18 P2X PURINOCEPTOR P2X PURINOCEPTOR 4 ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 transport#GO:0006810;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;calcium ion transmembrane transport#GO:0070588;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000001808.4|UniProtKB=F6RD58 F6RD58 ZNF646 PTHR24388:SF50 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 646 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000012855.4|UniProtKB=F7C9M4 F7C9M4 MCTP2 PTHR45911:SF2 C2 DOMAIN-CONTAINING PROTEIN MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 regulation of secretion#GO:0051046;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of secretion by cell#GO:1903530;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;regulation of neurotransmitter secretion#GO:0046928;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789 intracellular vesicle#GO:0097708;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;presynapse#GO:0098793;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasm#GO:0005737;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000048166.1|UniProtKB=A0A5F8GUV0 A0A5F8GUV0 PTHR45716:SF5 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;secretion by cell#GO:0032940;exocytosis#GO:0006887;transport#GO:0006810;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000005233.4|UniProtKB=F6ZCI9 F6ZCI9 LRP10 PTHR24270:SF17 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 10 low-density lipoprotein particle receptor activity#GO:0005041;cargo receptor activity#GO:0038024 transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876;establishment of localization#GO:0051234;lipid transport#GO:0006869;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transfer/carrier protein#PC00219;apolipoprotein#PC00052 MONDO|Ensembl=ENSMODG00000001377.4|UniProtKB=F7FJC1 F7FJC1 LOC100012029 PTHR11767:SF14 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 12-RELATED transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079 monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;cellular process#GO:0009987;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;transport#GO:0006810;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000016042.4|UniProtKB=F6YUM6 F6YUM6 HS3ST6 PTHR10605:SF62 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 6 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000002753.2|UniProtKB=F6Z693 F6Z693 AHCY PTHR23420:SF0 ADENOSYLHOMOCYSTEINASE ADENOSYLHOMOCYSTEINASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787 amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000006434.4|UniProtKB=A0A5F8H5C0 A0A5F8H5C0 QKI PTHR11208:SF42 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING RNA-BINDING PROTEIN QKI mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000018755.4|UniProtKB=K7E0W4 K7E0W4 TXNIP PTHR11188:SF14 ARRESTIN DOMAIN CONTAINING PROTEIN THIOREDOXIN-INTERACTING PROTEIN enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 response to stimulus#GO:0050896;response to oxidative stress#GO:0006979;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000018442.4|UniProtKB=F6XBK7 F6XBK7 RNF168 PTHR23328:SF1 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF168 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein-containing complex binding#GO:0044877;ubiquitin-protein transferase activity#GO:0004842;nucleosome binding#GO:0031491;chromatin binding#GO:0003682;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746 macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000040379.1|UniProtKB=A0A5F8H3C0 A0A5F8H3C0 RAB3B PTHR47980:SF22 LD44762P RAS-RELATED PROTEIN RAB-3B myosin binding#GO:0017022;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;exocytosis#GO:0006887;secretion by cell#GO:0032940;transport#GO:0006810;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987 endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;presynapse#GO:0098793;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000012575.4|UniProtKB=F6PJ15 F6PJ15 LOC100024568 PTHR11461:SF145 SERINE PROTEASE INHIBITOR, SERPIN SERPIN A3-5 peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000029095.2|UniProtKB=K7E0W7 K7E0W7 PTHR47048:SF1 PROTEIN SCAF11 PROTEIN SCAF11 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA splicing, via transesterification reactions#GO:0000375;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 MONDO|Ensembl=ENSMODG00000013507.4|UniProtKB=F7F8B1 F7F8B1 TRMT61A PTHR12133:SF2 TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE CATALYTIC SUBUNIT TRMT61A tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;methyltransferase complex#GO:0034708;transferase complex#GO:1990234;catalytic complex#GO:1902494 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000005375.4|UniProtKB=F6YKQ0 F6YKQ0 PTHR24115:SF400 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF16B microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774 transport#GO:0006810;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;microtubule-based process#GO:0007017;vesicle cytoskeletal trafficking#GO:0099518;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000044396.1|UniProtKB=F7A6X2 F7A6X2 LOC103095166 PTHR48018:SF28 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8K3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015850.4|UniProtKB=F7F0E6 F7F0E6 DNMT3A PTHR23068:SF10 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED DNA (CYTOSINE-5)-METHYLTRANSFERASE 3A catalytic activity, acting on DNA#GO:0140097;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a nucleic acid#GO:0140640 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DNA methyltransferase#PC00013 MONDO|Ensembl=ENSMODG00000013930.3|UniProtKB=F6SD95 F6SD95 KIF3A PTHR24115:SF472 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3A binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853 cellular component organization#GO:0016043;cilium assembly#GO:0060271;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;axonal transport#GO:0098930;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;anterograde axonal transport#GO:0008089;axo-dendritic transport#GO:0008088;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000013154.4|UniProtKB=F7ABY8 F7ABY8 BEGAIN PTHR28664:SF2 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 BRAIN-ENRICHED GUANYLATE KINASE-ASSOCIATED PROTEIN nervous system process#GO:0050877;trans-synaptic signaling#GO:0099537;regulation of biological quality#GO:0065008;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of postsynaptic membrane potential#GO:0060078;chemical synaptic transmission#GO:0007268;chemical synaptic transmission, postsynaptic#GO:0099565;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;system process#GO:0003008;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;signal transduction#GO:0007165;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000006507.4|UniProtKB=F7EJZ4 F7EJZ4 GUSB PTHR10066:SF68 BETA-GLUCURONIDASE BETA-GLUCURONIDASE catalytic activity#GO:0003824;binding#GO:0005488;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;carbohydrate binding#GO:0030246 protein metabolic process#GO:0019538;glycosaminoglycan catabolic process#GO:0006027;protein catabolic process#GO:0030163;aminoglycan metabolic process#GO:0006022;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;glycosaminoglycan metabolic process#GO:0030203;primary metabolic process#GO:0044238;proteoglycan metabolic process#GO:0006029;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;chondroitin sulfate proteoglycan metabolic process#GO:0050654;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000010248.2|UniProtKB=F6W675 F6W675 EBP PTHR14207:SF8 STEROL ISOMERASE 3-BETA-HYDROXYSTEROID-DELTA(8),DELTA(7)-ISOMERASE isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity#GO:0003824 secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;secondary alcohol biosynthetic process#GO:1902653;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 isomerase#PC00135 MONDO|Ensembl=ENSMODG00000004585.4|UniProtKB=F6QJJ0 F6QJJ0 NDUFB6 PTHR15083:SF0 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6 oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000024931.3|UniProtKB=F6RAU7 F6RAU7 PTHR14096:SF27 APOLIPOPROTEIN L APOLIPOPROTEIN L2 binding#GO:0005488;lipid binding#GO:0008289 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transfer/carrier protein#PC00219;apolipoprotein#PC00052 MONDO|Ensembl=ENSMODG00000009463.4|UniProtKB=F7FZE2 F7FZE2 CLK3 PTHR45646:SF10 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED DUAL SPECIFICITY PROTEIN KINASE CLK3 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000006792.3|UniProtKB=F6PH04 F6PH04 PSEN1 PTHR10202:SF18 PRESENILIN PRESENILIN-1 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 cell surface receptor signaling pathway#GO:0007166;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;Notch signaling pathway#GO:0007219;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;membrane protein ectodomain proteolysis#GO:0006509;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;proteolysis#GO:0006508;protein metabolic process#GO:0019538;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;homeostatic process#GO:0042592;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 catalytic complex#GO:1902494;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020 aspartic protease#PC00053;protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>Presenilin#P00098;Alzheimer disease-presenilin pathway#P00004>Presenilin N-terminal fragment#P00140;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin C-terminal fragment#P00102;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin N-terminal fragment#P00088;Alzheimer disease-presenilin pathway#P00004>Presenilin C-terminal fragment#P00155;Notch signaling pathway#P00045>Presenilin#P01110;Alzheimer disease-presenilin pathway#P00004>Presenilin#P00129 MONDO|Ensembl=ENSMODG00000042591.1|UniProtKB=A0A5F8GDS5 A0A5F8GDS5 PTHR24353:SF82 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;system process#GO:0003008;renal absorption#GO:0070293;signal transduction#GO:0007165;renal system process#GO:0003014;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;cytosol#GO:0005829;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Nicotine pharmacodynamics pathway#P06587>PRKACA#P06588;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;GABA-B receptor II signaling#P05731>PKA#P05752;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Endothelin signaling pathway#P00019>PKA#P00570;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-c#P00707;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Enkephalin release#P05913>PKA#P05972;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050 MONDO|Ensembl=ENSMODG00000005633.3|UniProtKB=F7BWR5 F7BWR5 PTHR11461:SF204 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B6 peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;extracellular region#GO:0005576 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000008402.4|UniProtKB=A0A5F8GCK3 A0A5F8GCK3 HNRNPK PTHR10288:SF356 KH DOMAIN CONTAINING RNA BINDING PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA splicing#GO:0043484;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000002383.3|UniProtKB=F7F029 F7F029 CAMK2N2 PTHR31007:SF1 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE II INHIBITOR 2 CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE II INHIBITOR 2 enzyme inhibitor activity#GO:0004857;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;kinase inhibitor activity#GO:0019210;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 kinase inhibitor#PC00139 MONDO|Ensembl=ENSMODG00000017359.4|UniProtKB=F6W8S3 F6W8S3 LOC100022070 PTHR19143:SF467 FIBRINOGEN/TENASCIN/ANGIOPOEITIN MGC64358 PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000002113.4|UniProtKB=F6UGN7 F6UGN7 TSPAN1 PTHR19282:SF216 TETRASPANIN TETRASPANIN-1 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000027581.2|UniProtKB=M9MMH0 M9MMH0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000046561.1|UniProtKB=H9H961 H9H961 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000003820.3|UniProtKB=O77617 O77617 CDKN2A PTHR24201:SF8 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CYCLIN-DEPENDENT KINASE 4 INHIBITOR B kinase inhibitor activity#GO:0019210;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;negative regulation of cell population proliferation#GO:0008285;regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564;regulation of cell cycle G1/S phase transition#GO:1902806;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell population proliferation#GO:0042127 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 p53 pathway#P00059>ARF#G01574 MONDO|Ensembl=ENSMODG00000017566.4|UniProtKB=A0A5F8H3T3 A0A5F8H3T3 SNAPC4 PTHR46621:SF1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;snRNA transcription by RNA polymerase III#GO:0042796;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA transcription by RNA polymerase II#GO:0042795;transcription by RNA polymerase III#GO:0006383;snRNA transcription#GO:0009301;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000011870.3|UniProtKB=F7G2V1 F7G2V1 MRI1 PTHR43475:SF1 METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853 purine-containing compound metabolic process#GO:0072521;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;proteinogenic amino acid metabolic process#GO:0170039;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 isomerase#PC00135 MONDO|Ensembl=ENSMODG00000001937.4|UniProtKB=F6VKB5 F6VKB5 TC2N PTHR46887:SF1 TANDEM C2 DOMAINS NUCLEAR PROTEIN TANDEM C2 DOMAINS NUCLEAR PROTEIN MONDO|Ensembl=ENSMODG00000017239.5|UniProtKB=F6U1M7 F6U1M7 DPP7 PTHR11010:SF107 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED DIPEPTIDYL PEPTIDASE 2 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000025533.3|UniProtKB=F6V1I2 F6V1I2 PTHR14098:SF2 SH2 DOMAIN CONTAINING PROTEIN CYTOKINE-DEPENDENT HEMATOPOIETIC CELL LINKER protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;leukocyte activation#GO:0045321;intracellular signal transduction#GO:0035556;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell activation#GO:0001775;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;immune system process#GO:0002376;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;myeloid leukocyte activation#GO:0002274;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000043154.1|UniProtKB=A0A5F8GHL5 A0A5F8GHL5 HOPX PTHR21408:SF1 HOMEODOMAIN-ONLY PROTEIN HOMEODOMAIN-ONLY PROTEIN molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;heart development#GO:0007507;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000017836.5|UniProtKB=F6Z8X8 F6Z8X8 RSPH4A PTHR13159:SF0 RADIAL SPOKEHEAD-RELATED RADIAL SPOKE HEAD COMPONENT 4A cilium movement#GO:0003341;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607 membraneless organelle#GO:0043228;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000020089.4|UniProtKB=F7ESS0 F7ESS0 RHOBTB3 PTHR24413:SF239 SPECKLE-TYPE POZ PROTEIN RHO-RELATED BTB DOMAIN-CONTAINING PROTEIN 3 ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488 regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000028814.2|UniProtKB=K7E161 K7E161 PTHR10642:SF35 RIBONUCLEASE H1 RIBONUCLEASE H1 hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519 cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;DNA-templated DNA replication#GO:0006261;mitochondrial DNA metabolic process#GO:0032042 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 endoribonuclease#PC00094;RNA metabolism protein#PC00031 DNA replication#P00017>RNase H#P00538 MONDO|Ensembl=ENSMODG00000044497.1|UniProtKB=A0A5F8GMY3 A0A5F8GMY3 MSANTD3 PTHR21632:SF2 REGULATORY PROTEIN ZESTE MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 3 MONDO|Ensembl=ENSMODG00000015266.3|UniProtKB=F6U326 F6U326 ATMIN PTHR46664:SF1 ATM INTERACTOR ATM INTERACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000009901.5|UniProtKB=F6UUX8 F6UUX8 FTSJ3 PTHR10920:SF13 RIBOSOMAL RNA METHYLTRANSFERASE PRE-RRNA 2'-O-RIBOSE RNA METHYLTRANSFERASE FTSJ3 catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;O-methyltransferase activity#GO:0008171;rRNA methyltransferase activity#GO:0008649;rRNA (guanine) methyltransferase activity#GO:0016435;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740 rRNA processing#GO:0006364;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;macromolecule biosynthetic process#GO:0009059;methylation#GO:0032259;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome, large subunit precursor#GO:0030687 RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000003183.3|UniProtKB=A0A5F8GIR0 A0A5F8GIR0 UTP4 PTHR44163:SF1 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774 small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;t-UTP complex#GO:0034455;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000042333.1|UniProtKB=F7F2A8 F7F2A8 GTF3C6 PTHR21860:SF2 TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 6-RELATED GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 6 RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991;transcription factor TFIIIC complex#GO:0000127 MONDO|Ensembl=ENSMODG00000024670.2|UniProtKB=F7AFV7 F7AFV7 TMEM239 PTHR37356:SF1 TRANSMEMBRANE PROTEIN 239 TRANSMEMBRANE PROTEIN 239 MONDO|Ensembl=ENSMODG00000007532.4|UniProtKB=F7GB60 F7GB60 RECQL5 PTHR13710:SF152 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q5 3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;response to stimulus#GO:0050896;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stress#GO:0033554;recombinational repair#GO:0000725 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 DNA helicase#PC00011;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000012120.4|UniProtKB=A0A5F8H3N6 A0A5F8H3N6 INTU PTHR21082:SF4 PROTEIN INTURNED PROTEIN INTURNED anatomical structure development#GO:0048856;system development#GO:0048731;cilium organization#GO:0044782;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000013032.5|UniProtKB=F7BNH8 F7BNH8 NR1D1 PTHR24082:SF113 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1 GROUP D MEMBER 1 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837 response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of transcription by RNA polymerase II#GO:0045944;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;cellular response to hormone stimulus#GO:0032870;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;hormone-mediated signaling pathway#GO:0009755;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular response to chemical stimulus#GO:0070887;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000036691.1|UniProtKB=A0A5F8G8X6 A0A5F8G8X6 PTHR19944:SF64 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DP ALPHA 1 CHAIN protein-containing complex binding#GO:0044877;binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of cell-cell adhesion#GO:0022409;cellular component biogenesis#GO:0044085;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;positive regulation of leukocyte activation#GO:0002696;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;regulation of lymphocyte activation#GO:0051249;immune system process#GO:0002376;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of cell adhesion#GO:0045785;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882 plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;protein-containing complex#GO:0032991;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 MONDO|Ensembl=ENSMODG00000037538.1|UniProtKB=A0A5F8H8E5 A0A5F8H8E5 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004169.4|UniProtKB=F6QPV8 F6QPV8 APOH PTHR19325:SF549 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING BETA-2-GLYCOPROTEIN 1 defense/immunity protein#PC00090;complement component#PC00078 MONDO|Ensembl=ENSMODG00000004459.4|UniProtKB=A0A5F8HE59 A0A5F8HE59 PBX4 PTHR11850:SF98 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 4 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677 neuron development#GO:0048666;eye development#GO:0001654;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;embryo development#GO:0009790;head development#GO:0060322;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;sensory system development#GO:0048880;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;embryonic organ development#GO:0048568;visual system development#GO:0150063;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000046459.1|UniProtKB=A0A5F8GQX0 A0A5F8GQX0 PTHR45701:SF23 SYNAPTOBREVIN FAMILY MEMBER V-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;SNAP receptor activity#GO:0005484;syntaxin binding#GO:0019905;protein binding#GO:0005515 transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;membrane fusion#GO:0061025;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;localization#GO:0051179;secretion#GO:0046903;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of body fluid levels#GO:0050878;vesicle fusion#GO:0006906 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000048978.1|UniProtKB=A0A5F8G3Y2 A0A5F8G3Y2 LOC100617107 PTHR26453:SF156 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023285.2|UniProtKB=F6RVS1 F6RVS1 SLC2A7 PTHR23503:SF30 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 7 sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180;carbohydrate transport#GO:0008643;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;import into cell#GO:0098657 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000011457.3|UniProtKB=F7E7W7 F7E7W7 CCR3 PTHR10489:SF649 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 3 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375 intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;response to stress#GO:0006950;calcium-mediated signaling#GO:0019722;defense response#GO:0006952;response to external stimulus#GO:0009605;locomotion#GO:0040011;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cell communication#GO:0007154;chemotaxis#GO:0006935;inflammatory response#GO:0006954;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376 external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000007179.4|UniProtKB=F6XS15 F6XS15 FXR2 PTHR10603:SF3 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN RNA-BINDING PROTEIN FXR2 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;positive regulation of nervous system development#GO:0051962;positive regulation of cell differentiation#GO:0045597;animal organ development#GO:0048513;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;regulation of trans-synaptic signaling#GO:0099177;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of translation#GO:0045727;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;nucleic acid transport#GO:0050657;positive regulation of biosynthetic process#GO:0009891;localization#GO:0051179;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;establishment of RNA localization#GO:0051236;modulation of chemical synaptic transmission#GO:0050804;mRNA transport#GO:0051028;RNA transport#GO:0050658;RNA localization#GO:0006403;regulation of cellular process#GO:0050794;nucleobase-containing compound transport#GO:0015931;regulation of macromolecule metabolic process#GO:0060255;regulation of cell differentiation#GO:0045595;transport#GO:0006810;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;post-transcriptional regulation of gene expression#GO:0010608;regulation of synaptic plasticity#GO:0048167;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;regulation of neuronal synaptic plasticity#GO:0048168;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;nitrogen compound transport#GO:0071705;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;neuron projection#GO:0043005;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translation factor#PC00223;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000025669.2|UniProtKB=F6XDA3 F6XDA3 PTHR23239:SF207 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 24 structural molecule activity#GO:0005198 organelle organization#GO:0006996;cellular process#GO:0009987;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;morphogenesis of an epithelium#GO:0002009;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000012813.4|UniProtKB=F7DYP4 F7DYP4 MYLK3 PTHR24347:SF394 SERINE/THREONINE-PROTEIN KINASE MYOSIN LIGHT CHAIN KINASE 3 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 striated muscle tissue development#GO:0014706;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cardiac muscle cell differentiation#GO:0055007;cytoskeleton organization#GO:0007010;heart development#GO:0007507;cellular component assembly#GO:0022607;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell development#GO:0048468;actomyosin structure organization#GO:0031032;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cell differentiation#GO:0030154;developmental process#GO:0032502;cellular developmental process#GO:0048869;cardiac muscle tissue development#GO:0048738;biological regulation#GO:0065007;tissue development#GO:0009888;multicellular organismal process#GO:0032501;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;muscle tissue development#GO:0060537;supramolecular fiber organization#GO:0097435;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877 MONDO|Ensembl=ENSMODG00000024367.2|UniProtKB=A0A5F8HHB1 A0A5F8HHB1 JRK PTHR19303:SF11 TRANSPOSON JERKY PROTEIN HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012032.4|UniProtKB=F7ALS4 F7ALS4 SELENOS PTHR28621:SF1 SELENOPROTEIN S SELENOPROTEIN S biological regulation#GO:0065007;macromolecule localization#GO:0033036;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;transport#GO:0006810;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;localization#GO:0051179;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;establishment of protein localization#GO:0045184;signal transduction#GO:0007165;cellular process#GO:0009987;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of biological process#GO:0050789;response to unfolded protein#GO:0006986;protein transport#GO:0015031;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 MONDO|Ensembl=ENSMODG00000010511.4|UniProtKB=A0A5F8HFH0 A0A5F8HFH0 DGUOK PTHR10513:SF8 DEOXYNUCLEOSIDE KINASE DEOXYGUANOSINE KINASE, MITOCHONDRIAL deoxynucleoside kinase activity#GO:0019136;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 MONDO|Ensembl=ENSMODG00000005890.4|UniProtKB=A0A5F8GQC2 A0A5F8GQC2 SLC24A3 PTHR10846:SF42 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 3 potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000013086.4|UniProtKB=A0A5F8H0Q0 A0A5F8H0Q0 NIPAL3 PTHR12570:SF14 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED NIPA-LIKE PROTEIN 3 magnesium ion transport#GO:0015693;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000008249.4|UniProtKB=A0A5F8GKF7 A0A5F8GKF7 PTHR11653:SF3 PARVALBUMIN ALPHA PARVALBUMIN, THYMIC ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000027761.2|UniProtKB=K7E347 K7E347 RGS21 PTHR10845:SF160 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 21 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 regulation of biological process#GO:0050789;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944 GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000005437.3|UniProtKB=F7D0N0 F7D0N0 PTHR11905:SF148 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 30 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;development of primary male sexual characteristics#GO:0046546;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;male sex differentiation#GO:0046661;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;animal organ development#GO:0048513;male gonad development#GO:0008584;cellular process#GO:0009987;sex differentiation#GO:0007548;multicellular organismal process#GO:0032501;gonad development#GO:0008406;proteolysis#GO:0006508;animal gross anatomical part developmental process#GO:0160108;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;system development#GO:0048731;reproductive system development#GO:0061458;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;reproductive structure development#GO:0048608;reproductive process#GO:0022414 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000050126.1|UniProtKB=K7E0J4 K7E0J4 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000011141.4|UniProtKB=F7DC02 F7DC02 ZNF79 PTHR24377:SF975 IP01015P-RELATED ZINC FINGER PROTEIN 883-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000013562.3|UniProtKB=F7C2V3 F7C2V3 KRT20 PTHR23239:SF167 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 20 structural molecule activity#GO:0005198 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular process#GO:0009987;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;morphogenesis of an epithelium#GO:0002009 intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000002419.4|UniProtKB=A0A5F8GIN6 A0A5F8GIN6 CFAP20DC PTHR12458:SF7 ORF PROTEIN PROTEIN CFAP20DC MONDO|Ensembl=ENSMODG00000023107.1|UniProtKB=F7ACL6 F7ACL6 GPR75 PTHR24228:SF55 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G PROTEIN-COUPLED RECEPTOR 75-RELATED cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011127.4|UniProtKB=F7BB60 F7BB60 PLEKHM1 PTHR12326:SF5 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 1 MONDO|Ensembl=ENSMODG00000004533.4|UniProtKB=A0A5F8GYG9 A0A5F8GYG9 LOC100025736 PTHR12560:SF6 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;ceramide metabolic process#GO:0006672 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000013791.2|UniProtKB=F6TE57 F6TE57 IL1F10 PTHR10078:SF29 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-1 FAMILY MEMBER 10 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to oxygen-containing compound#GO:1901700;response to peptide#GO:1901652;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;response to cytokine#GO:0034097;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cytokine-mediated signaling pathway#GO:0019221;response to bacterium#GO:0009617;inflammatory response#GO:0006954;cell communication#GO:0007154;immune response#GO:0006955;response to other organism#GO:0051707;biological regulation#GO:0065007;cellular response to molecule of bacterial origin#GO:0071219;defense response#GO:0006952;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083;interleukin superfamily#PC00128;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000012212.4|UniProtKB=F7CE32 F7CE32 PTHR46679:SF1 FAMILY NOT NAMED GLUTAREDOXIN-2, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 MONDO|Ensembl=ENSMODG00000020842.4|UniProtKB=F6R1G7 F6R1G7 PTHR24416:SF552 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR PROTEIN-TYROSINE KINASE transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cell migration#GO:0016477;biological regulation#GO:0065007 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>VEGFR-2#P00222;VEGF signaling pathway#P00056>VEGFR-2#P01403 MONDO|Ensembl=ENSMODG00000037798.1|UniProtKB=A0A5F8GLA0 A0A5F8GLA0 PTHR40141:SF2 3',5'-CYCLIC-AMP PHOSPHODIESTERASE-RELATED 3',5'-CYCLIC-AMP PHOSPHODIESTERASE MONDO|Ensembl=ENSMODG00000024617.2|UniProtKB=F6XVZ4 F6XVZ4 PTHR24381:SF27 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 180 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014991.3|UniProtKB=F7CG49 F7CG49 CER1 PTHR15273:SF4 DAN DOMAIN FAMILY MEMBER 5 CERBERUS molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 negative regulation of cell communication#GO:0010648;animal gross anatomical part developmental process#GO:0160108;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;circulatory system development#GO:0072359;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;animal organ development#GO:0048513;anterior/posterior axis specification#GO:0009948;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;left/right pattern formation#GO:0060972;heart development#GO:0007507;determination of bilateral symmetry#GO:0009855;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;cellular response to stimulus#GO:0051716;determination of left/right symmetry#GO:0007368;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;specification of symmetry#GO:0009799;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;regionalization#GO:0003002;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Wnt signaling pathway#P00057>Cerebus#P01445 MONDO|Ensembl=ENSMODG00000017179.3|UniProtKB=F6XYM3 F6XYM3 FAM185A PTHR34094:SF1 FAMILY NOT NAMED PROTEIN FAM185A MONDO|Ensembl=ENSMODG00000002718.4|UniProtKB=A0A5F8GVD0 A0A5F8GVD0 ERCC6L2 PTHR45629:SF14 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE 2 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 damaged DNA-binding protein#PC00086 MONDO|Ensembl=ENSMODG00000036914.1|UniProtKB=F6XU56 F6XU56 PTHR26452:SF310 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000013621.1|UniProtKB=F6VE50 F6VE50 LOC100024874 PTHR13362:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S33 SMALL RIBOSOMAL SUBUNIT PROTEIN MS33 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000046485.1|UniProtKB=A0A5F8GNV0 A0A5F8GNV0 LOC100029733 PTHR10516:SF301 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1A-RELATED catalytic activity#GO:0003824;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;cis-trans isomerase activity#GO:0016859;catalytic activity, acting on a protein#GO:0140096 calcium-mediated signaling#GO:0019722;macromolecule metabolic process#GO:0043170;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of system process#GO:0044057;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of monoatomic ion transport#GO:0043269;macromolecule biosynthetic process#GO:0009059;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;protein metabolic process#GO:0019538;regulation of heart contraction#GO:0008016;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;regulation of transmembrane transport#GO:0034762;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of release of sequestered calcium ion into cytosol#GO:0051279;metabolic process#GO:0008152;regulation of multicellular organismal process#GO:0051239;intracellular signaling cassette#GO:0141124;protein maturation#GO:0051604;gene expression#GO:0010467;signal transduction#GO:0007165;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;regulation of muscle contraction#GO:0006937;signaling#GO:0023052;protein folding#GO:0006457;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of muscle system process#GO:0090257 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;sarcoplasm#GO:0016528;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;sarcoplasmic reticulum membrane#GO:0033017;cytoplasm#GO:0005737;membrane#GO:0016020;sarcoplasmic reticulum#GO:0016529 chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 MONDO|Ensembl=ENSMODG00000005548.4|UniProtKB=A0A5F8GAC1 A0A5F8GAC1 ANGEL1 PTHR12121:SF28 CARBON CATABOLITE REPRESSOR PROTEIN 4 RNA 2',3'-CYCLIC PHOSPHATASE ANGEL1 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;mRNA 3'-UTR binding#GO:0003730;nuclease activity#GO:0004518;binding#GO:0005488;mRNA binding#GO:0003729;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;RNA binding#GO:0003723;hydrolase activity#GO:0016787;nucleic acid binding#GO:0003676 nucleobase-containing compound metabolic process#GO:0006139;mitochondrial RNA processing#GO:0000963;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;catabolic process#GO:0009056;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;negative regulation of macromolecule biosynthetic process#GO:0010558;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;positive regulation of mRNA metabolic process#GO:1903313;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;RNA processing#GO:0006396;mitochondrial RNA 3'-end processing#GO:0000965;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;mRNA processing#GO:0006397;RNA destabilization#GO:0050779;RNA 3'-end processing#GO:0031123;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739 mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000012206.4|UniProtKB=F7CE61 F7CE61 BRAP PTHR24007:SF7 BRCA1-ASSOCIATED PROTEIN BRCA1-ASSOCIATED PROTEIN ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;protein modification by small protein conjugation or removal#GO:0070647;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;post-translational protein modification#GO:0043687;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000001943.4|UniProtKB=K7DZ82 K7DZ82 PCNP PTHR16523:SF6 PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000046464.1|UniProtKB=A0A5F8GJU7 A0A5F8GJU7 PTHR19944:SF59 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ ALPHA 1 CHAIN protein-containing complex binding#GO:0044877;peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488 positive regulation of cell adhesion#GO:0045785;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte activation#GO:0051251;positive regulation of cellular process#GO:0048522;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of lymphocyte activation#GO:0051249;immune system process#GO:0002376;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of T cell activation#GO:0050863;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;positive regulation of leukocyte activation#GO:0002696;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 MONDO|Ensembl=ENSMODG00000011374.4|UniProtKB=F6SPK9 F6SPK9 TIE1 PTHR24416:SF341 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR TIE-1 transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096 regulation of anatomical structure morphogenesis#GO:0022603;cell surface receptor signaling pathway#GO:0007166;positive regulation of developmental process#GO:0051094;regulation of vasculature development#GO:1901342;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of angiogenesis#GO:0045765;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of angiogenesis#GO:0045766 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028124.2|UniProtKB=K7E375 K7E375 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000013607.3|UniProtKB=A0A5F8GN37 A0A5F8GN37 ACKR2 PTHR10489:SF942 CELL ADHESION MOLECULE ATYPICAL CHEMOKINE RECEPTOR 2 cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;chemotaxis#GO:0006935;cell communication#GO:0007154;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 cell adhesion molecule#PC00069 MONDO|Gene=ADI1|UniProtKB=F7FKV1 F7FKV1 ADI1 PTHR23418:SF0 ACIREDUCTONE DIOXYGENASE ACIREDUCTONE DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000045753.1|UniProtKB=A0A5F8GYL2 A0A5F8GYL2 PROB1 PTHR33775:SF1 CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN-RELATED PROLINE-RICH BASIC PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000027533.2|UniProtKB=K7E664 K7E664 LOC103102061 PTHR16983:SF27 UPAR/LY6 DOMAIN-CONTAINING PROTEIN LY-6_NEUROTOXIN-LIKE PROTEIN 1 acetylcholine receptor regulator activity#GO:0030548;acetylcholine receptor inhibitor activity#GO:0030550;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;neurotransmitter receptor regulator activity#GO:0099602;molecular function inhibitor activity#GO:0140678;signaling receptor inhibitor activity#GO:0030547;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772 signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000048346.1|UniProtKB=A0A5F8GBR8 A0A5F8GBR8 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000019856.3|UniProtKB=H9H7J0 H9H7J0 PTHR21713:SF3 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;protein targeting#GO:0006605;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000012681.4|UniProtKB=F6VG93 F6VG93 PAX9 PTHR45636:SF13 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-9 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000010136.4|UniProtKB=A0A5F8HB62 A0A5F8HB62 PTHR22705:SF0 ZINC FINGER, ZZ DOMAIN CONTAINING 3 ZZ-TYPE ZINC FINGER-CONTAINING PROTEIN 3 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000007086.4|UniProtKB=F6UEJ0 F6UEJ0 SPDL1 PTHR32123:SF9 BICD FAMILY-LIKE CARGO ADAPTER PROTEIN SPINDLY binding#GO:0005488 mitotic sister chromatid segregation#GO:0000070;macromolecule localization#GO:0033036;protein localization to kinetochore#GO:0034501;establishment of spindle localization#GO:0051293;establishment of mitotic spindle orientation#GO:0000132;establishment of localization#GO:0051234;mitotic cell cycle process#GO:1903047;intracellular protein localization#GO:0008104;chromosome organization#GO:0051276;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;establishment of cell polarity#GO:0030010;mitotic metaphase chromosome alignment#GO:0007080;mitotic cell cycle#GO:0000278;protein localization to organelle#GO:0033365;organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;establishment of organelle localization#GO:0051656;establishment or maintenance of cell polarity#GO:0007163;nuclear division#GO:0000280;cellular localization#GO:0051641;spindle localization#GO:0051653 outer kinetochore#GO:0000940;membraneless organelle#GO:0043228;spindle#GO:0005819;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;spindle pole#GO:0000922;chromosome#GO:0005694 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000023803.3|UniProtKB=F6RN11 F6RN11 PTHR12035:SF125 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 5 organic acid binding#GO:0043177;carbohydrate derivative binding#GO:0097367;ion binding#GO:0043167;binding#GO:0005488;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;small molecule binding#GO:0036094 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000017627.4|UniProtKB=F6ZSH1 F6ZSH1 SQOR PTHR10632:SF2 SULFIDE:QUINONE OXIDOREDUCTASE SULFIDE:QUINONE OXIDOREDUCTASE, MITOCHONDRIAL ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;binding#GO:0005488;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000013062.2|UniProtKB=F7FQ25 F7FQ25 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000002694.1|UniProtKB=F7CYB7 F7CYB7 MAP1LC3A PTHR10969:SF14 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED MICROTUBULE-ASSOCIATED PROTEIN 1 LIGHT CHAIN 3 ALPHA lipid binding#GO:0008289;protein binding#GO:0005515;enzyme binding#GO:0019899;microtubule binding#GO:0008017;binding#GO:0005488;ubiquitin protein ligase binding#GO:0031625;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;ubiquitin-like protein ligase binding#GO:0044389;phospholipid binding#GO:0005543 mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;cellular response to starvation#GO:0009267;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;cellular response to nutrient levels#GO:0031669;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;organelle organization#GO:0006996;response to stress#GO:0006950;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component disassembly#GO:0022411;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;organelle assembly#GO:0070925;cellular response to stress#GO:0033554;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein-containing complex disassembly#GO:0032984;response to starvation#GO:0042594;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;autophagosome#GO:0005776;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000001952.5|UniProtKB=F6VJN4 F6VJN4 KHSRP PTHR10288:SF101 KH DOMAIN CONTAINING RNA BINDING PROTEIN FAR UPSTREAM ELEMENT-BINDING PROTEIN 2 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;regulation of biological quality#GO:0065008;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000037564.1|UniProtKB=A0A5F8HC69 A0A5F8HC69 APOBEC4 PTHR35672:SF1 C-U-EDITING ENZYME APOBEC-4-RELATED DEAMINASE APOBEC-4-RELATED MONDO|Ensembl=ENSMODG00000001001.4|UniProtKB=F7E9M6 F7E9M6 ALDH7A1 PTHR43521:SF9 ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cytosol#GO:0005829;nucleus#GO:0005634;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 MONDO|Ensembl=ENSMODG00000024070.3|UniProtKB=F7D2J3 F7D2J3 SAMD14 PTHR16154:SF28 NEURABIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 14 molecular adaptor activity#GO:0060090;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;protein-membrane adaptor activity#GO:0043495 supramolecular fiber organization#GO:0097435;system development#GO:0048731;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cellular response to stimulus#GO:0051716;actin filament organization#GO:0007015;calcium-mediated signaling#GO:0019722;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175 actin-based cell projection#GO:0098858;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;postsynapse#GO:0098794;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;filopodium#GO:0030175;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;neuron projection#GO:0043005;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000024641.3|UniProtKB=F6XCD8 F6XCD8 FAM8A1 PTHR13659:SF5 AUTOSOMAL HIGHLY CONSERVED PROTEIN PROTEIN FAM8A1 MONDO|Ensembl=ENSMODG00000000175.4|UniProtKB=F6TGF1 F6TGF1 CDK5RAP1 PTHR43020:SF2 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 1 MITOCHONDRIAL TRNA METHYLTHIOTRANSFERASE CDK5RAP1 catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;transferase activity, transferring sulphur-containing groups#GO:0016782;iron-sulfur cluster binding#GO:0051536;binding#GO:0005488;small molecule binding#GO:0036094 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;mitochondrial gene expression#GO:0140053;mitochondrial RNA modification#GO:1900864;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000002866.3|UniProtKB=A0A5F8H9I6 A0A5F8H9I6 PPP2R2C PTHR11871:SF5 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B GAMMA ISOFORM protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629 MONDO|Ensembl=ENSMODG00000041272.1|UniProtKB=A0A5F8H922 A0A5F8H922 PTHR48160:SF1 LARGE RIBOSOMAL SUBUNIT PROTEIN EL43 LARGE RIBOSOMAL SUBUNIT PROTEIN EL43 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000002027.4|UniProtKB=F6QWK7 F6QWK7 ATAD2 PTHR23069:SF4 AAA DOMAIN-CONTAINING ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;histone binding#GO:0042393;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;biological regulation#GO:0065007;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;transcription by RNA polymerase II#GO:0006366;nucleosome organization#GO:0034728;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;protein-containing complex disassembly#GO:0032984;DNA-templated transcription#GO:0006351;positive regulation of biosynthetic process#GO:0009891;transcription initiation at RNA polymerase II promoter#GO:0006367;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;transcription initiation-coupled chromatin remodeling#GO:0045815;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;DNA-templated transcription initiation#GO:0006352;chromatin remodeling#GO:0006338;nucleic acid biosynthetic process#GO:0141187;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular component disassembly#GO:0022411;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000004847.4|UniProtKB=F6U5A9 F6U5A9 INIP PTHR31526:SF3 SOSS COMPLEX SUBUNIT C SOSS COMPLEX SUBUNIT C DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000018407.4|UniProtKB=F7GK59 F7GK59 ERC1 PTHR18861:SF1 ELKS/RAB6-INTERACTING/CAST PROTEIN ELKS_RAB6-INTERACTING_CAST FAMILY MEMBER 1 structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 presynaptic active zone#GO:0048786;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;presynapse#GO:0098793;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cytoplasm#GO:0005737 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000007237.3|UniProtKB=F6WBV4 F6WBV4 PTHR23343:SF4 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 enzyme binding#GO:0019899;extracellular matrix structural constituent#GO:0005201;binding#GO:0005488;structural molecule activity#GO:0005198;protein binding#GO:0005515 multicellular organismal process#GO:0032501;regulation of reproductive process#GO:2000241;fertilization#GO:0009566;reproductive process#GO:0022414;biological regulation#GO:0065007;single fertilization#GO:0007338;negative regulation of biological process#GO:0048519;cellular process#GO:0009987;regulation of biological process#GO:0050789;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988;sperm-egg recognition#GO:0035036;cell recognition#GO:0008037;cell activation#GO:0001775;sexual reproduction#GO:0019953 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000019425.3|UniProtKB=F6SG91 F6SG91 ZFYVE16 PTHR46319:SF1 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 16 vesicle-mediated transport#GO:0016192;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;vacuolar transport#GO:0007034;protein targeting#GO:0006605;protein localization to organelle#GO:0033365;establishment of protein localization to vacuole#GO:0072666;protein localization to lysosome#GO:0061462;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein localization to vacuole#GO:0072665;lysosomal transport#GO:0007041 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;vesicle membrane#GO:0012506 TGF-beta signaling pathway#P00052>SARA#P01281 MONDO|Ensembl=ENSMODG00000042810.1|UniProtKB=A0A5F8HBR2 A0A5F8HBR2 WNT8B PTHR12027:SF94 WNT RELATED PROTEIN WNT-8B signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125 neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;cell fate commitment#GO:0045165;system development#GO:0048731;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 MONDO|Ensembl=ENSMODG00000009773.4|UniProtKB=F6TF95 F6TF95 FAM217A PTHR22145:SF4 SI:CH211-266K22.6 PROTEIN FAM217A MONDO|Ensembl=ENSMODG00000051269.1|UniProtKB=A0A5F8HHU8 A0A5F8HHU8 C1orf198 PTHR34394:SF1 SIMILAR TO RIKEN CDNA 2310022B05 SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 198 MONDO|Ensembl=ENSMODG00000003627.4|UniProtKB=A0A5F8GL40 A0A5F8GL40 LOC130453543 PTHR10903:SF199 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000007502.4|UniProtKB=F6YX02 F6YX02 CPXM2 PTHR11532:SF45 PROTEASE M14 CARBOXYPEPTIDASE INACTIVE CARBOXYPEPTIDASE-LIKE PROTEIN X2 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 MONDO|Ensembl=ENSMODG00000001338.4|UniProtKB=F7FWC0 F7FWC0 PTHR11177:SF248 CHITINASE OVIDUCT-SPECIFIC GLYCOPROTEIN hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568 chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000048054.1|UniProtKB=A0A5F8HCZ3 A0A5F8HCZ3 PTHR21660:SF1 THIOESTERASE SUPERFAMILY MEMBER-RELATED ACYL-COENZYME A THIOESTERASE 13 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;fatty acyl-CoA hydrolase activity#GO:0047617;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788 hydrolase#PC00121;esterase#PC00097;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000029047.2|UniProtKB=A0A5F8GNJ6 A0A5F8GNJ6 PTHR37339:SF1 TESTIS-EXPRESSED PROTEIN 29 TESTIS-EXPRESSED PROTEIN 29 MONDO|Ensembl=ENSMODG00000015404.5|UniProtKB=A0A5F8G2H1 A0A5F8G2H1 PTHR24392:SF60 ZINC FINGER PROTEIN ZINC FINGER Y-CHROMOSOMAL PROTEIN 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000041502.1|UniProtKB=A0A5F8GWL4 A0A5F8GWL4 PTHR45904:SF1 TRNA (URACIL-5-)-METHYLTRANSFERASE TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG B RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000015834.2|UniProtKB=F7FDR0 F7FDR0 PSORS1C2 PTHR31853:SF1 PSORIASIS SUSCEPTIBILITY 1 CANDIDATE GENE 2 PROTEIN PSORIASIS SUSCEPTIBILITY 1 CANDIDATE GENE 2 PROTEIN MONDO|Ensembl=ENSMODG00000041844.1|UniProtKB=F7CMW2 F7CMW2 LOC100031901 PTHR26453:SF20 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6B9 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007063.2|UniProtKB=F6UF37 F6UF37 PTHR48001:SF128 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023478.2|UniProtKB=F6YDG2 F6YDG2 PTHR11991:SF23 TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 negative regulation of cell communication#GO:0010648;negative regulation of catabolic process#GO:0009895;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;negative regulation of programmed cell death#GO:0043069;regulation of metabolic process#GO:0019222 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000016470.4|UniProtKB=A0A5F8HH11 A0A5F8HH11 BICDL2 PTHR32123:SF11 BICD FAMILY-LIKE CARGO ADAPTER BICD FAMILY-LIKE CARGO ADAPTER 2 organelle localization#GO:0051640;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;vesicle cytoskeletal trafficking#GO:0099518;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000013645.3|UniProtKB=F6UE04 F6UE04 ADCK2 PTHR45890:SF26 AARF DOMAIN CONTAINING KINASE 2 (PREDICTED) NADH:UBIQUINONE OXIDOREDUCTASE SUBUNIT B2 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000006110.4|UniProtKB=F7EIG4 F7EIG4 SHISAL1 PTHR31395:SF11 SHISA PROTEIN SHISA-LIKE-1 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000002867.3|UniProtKB=F7E2A9 F7E2A9 SH3BP4 PTHR15603:SF3 SH3 DOMAIN-CONTAINING PROTEIN SH3 DOMAIN-BINDING PROTEIN 4 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;response to chemical#GO:0042221;negative regulation of response to stimulus#GO:0048585;response to acid chemical#GO:0001101;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000003244.3|UniProtKB=F6THF0 F6THF0 RAC3 PTHR24072:SF325 RHO FAMILY GTPASE RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 3 hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553 cell differentiation#GO:0030154;cell projection organization#GO:0030030;signaling#GO:0023052;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;Rac protein signal transduction#GO:0016601;establishment or maintenance of cell polarity#GO:0007163;generation of neurons#GO:0048699;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;regulation of developmental process#GO:0050793;regulation of cell motility#GO:2000145;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;system development#GO:0048731;supramolecular fiber organization#GO:0097435;cortical cytoskeleton organization#GO:0030865;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;cellular developmental process#GO:0048869;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;cell morphogenesis#GO:0000902;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell development#GO:0048468;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;neuron development#GO:0048666;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;intracellular signaling cassette#GO:0141124;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;cell projection assembly#GO:0030031;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;axon guidance#GO:0007411;neurogenesis#GO:0022008;actin filament organization#GO:0007015;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 small GTPase#PC00208;G-protein#PC00020 EGF receptor signaling pathway#P00018>Rac#P00564;T cell activation#P00053>rac#P01324;Ras Pathway#P04393>Rac#P04559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Integrin signalling pathway#P00034>Rac#P00927;Huntington disease#P00029>Rac#P00775;FGF signaling pathway#P00021>Rac#P00645;Axon guidance mediated by netrin#P00009>Rac#P00366;Axon guidance mediated by semaphorins#P00007>Rac#P00340;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;VEGF signaling pathway#P00056>Rac#P01421;B cell activation#P00010>Rac#P00385;p38 MAPK pathway#P05918>Rac#P06021;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354 MONDO|Ensembl=ENSMODG00000006222.4|UniProtKB=F7FS75 F7FS75 PTHR24012:SF409 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 1 mRNA binding#GO:0003729;binding#GO:0005488;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730 post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000042022.1|UniProtKB=A0A5F8GRB6 A0A5F8GRB6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000041321.1|UniProtKB=A0A5F8HHV1 A0A5F8HHV1 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000007990.5|UniProtKB=F7D5M4 F7D5M4 PTHR12214:SF4 GC-RICH SEQUENCE DNA-BINDING FACTOR INTRON LARGE COMPLEX COMPONENT GCFC2 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000037821.1|UniProtKB=A0A5F8H5U1 A0A5F8H5U1 PTHR12207:SF27 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2B cellular anatomical structure#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000043252.1|UniProtKB=A0A5F8G7G7 A0A5F8G7G7 PTHR16675:SF67 MHC CLASS I-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000003106.4|UniProtKB=F6PIG6 F6PIG6 NECAP2 PTHR12847:SF16 ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED ADAPTIN EAR-BINDING COAT-ASSOCIATED PROTEIN 2 membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle#GO:0030136;clathrin-coated vesicle membrane#GO:0030665;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000010770.4|UniProtKB=F7FJV9 F7FJV9 ALOX5 PTHR11771:SF5 LIPOXYGENASE POLYUNSATURATED FATTY ACID 5-LIPOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;icosanoid metabolic process#GO:0006690;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;arachidonate metabolic process#GO:0019369;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000048463.1|UniProtKB=A0A5F8HGN2 A0A5F8HGN2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000014018.3|UniProtKB=F6V9J6 F6V9J6 HSPB6 PTHR45640:SF36 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN BETA-6 regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;negative regulation of programmed cell death#GO:0043069;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to heat#GO:0009408;response to stress#GO:0006950;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;gene expression#GO:0010467;protein maturation#GO:0051604;protein refolding#GO:0042026;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;protein folding#GO:0006457;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000001420.4|UniProtKB=F7BCV0 F7BCV0 LPCAT1 PTHR23063:SF57 PHOSPHOLIPID ACYLTRANSFERASE LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000023642.3|UniProtKB=F7DUY2 F7DUY2 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018444.3|UniProtKB=F6XBJ9 F6XBJ9 IRAK1BP1 PTHR18842:SF2 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1-BINDING PROTEIN 1 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1-BINDING PROTEIN 1 MONDO|Ensembl=ENSMODG00000007651.4|UniProtKB=A0A5F8G212 A0A5F8G212 CCNG1 PTHR10177:SF59 CYCLINS CYCLIN-G1 enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>CYCLIN G#G04715;p53 pathway#P00059>Cyclin G#G04689;p53 pathway feedback loops 2#P04398>cyclin G#P04662 MONDO|Ensembl=ENSMODG00000000787.4|UniProtKB=F6SSF5 F6SSF5 FAM221A PTHR31214:SF2 PROTEIN FAM221A-RELATED PROTEIN FAM221A MONDO|Ensembl=ENSMODG00000012124.4|UniProtKB=F7FU67 F7FU67 REEP2 PTHR12300:SF29 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 2 cytoskeletal protein binding#GO:0008092;G protein-coupled receptor binding#GO:0001664;tubulin binding#GO:0015631;microtubule binding#GO:0008017;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum tubular network organization#GO:0071786;endomembrane system organization#GO:0010256 cytoplasmic microtubule#GO:0005881;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;endoplasmic reticulum tubular network#GO:0071782;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoskeleton#GO:0005856;organelle membrane#GO:0031090;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000016232.4|UniProtKB=F7FLK8 F7FLK8 SLC2A10 PTHR48023:SF7 D-XYLOSE-PROTON SYMPORTER-LIKE 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 10 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144 transport#GO:0006810;carbohydrate transport#GO:0008643;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;localization#GO:0051179;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659;carbohydrate transmembrane transport#GO:0034219;multicellular organismal process#GO:0032501;circulatory system development#GO:0072359 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000025050.1|UniProtKB=F6W6S9 F6W6S9 PTHR15333:SF2 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 5 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 5 MONDO|Ensembl=ENSMODG00000002041.4|UniProtKB=A0A5F8HD03 A0A5F8HD03 CCDC85A PTHR13546:SF13 RE60986P COILED-COIL DOMAIN-CONTAINING PROTEIN 85A MONDO|Ensembl=ENSMODG00000018185.4|UniProtKB=A0A5F8GNN0 A0A5F8GNN0 LSAMP PTHR42757:SF22 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED LIMBIC SYSTEM-ASSOCIATED MEMBRANE PROTEIN cell-cell adhesion#GO:0098609;regulation of biological process#GO:0050789;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;regulation of synapse assembly#GO:0051963;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;cell adhesion#GO:0007155;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000010061.2|UniProtKB=F6Y592 F6Y592 TSSK2 PTHR24343:SF120 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular process#GO:0009987;male gamete generation#GO:0048232;spermatid differentiation#GO:0048515;sexual reproduction#GO:0019953;spermatid development#GO:0007286;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell differentiation#GO:0030154;gamete generation#GO:0007276;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000028279.2|UniProtKB=K7DYW7 K7DYW7 C1H15orf48 PTHR14256:SF3 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT CYTOCHROME C OXIDASE ASSOCIATED SUBUNIT FA4L3 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000023655.3|UniProtKB=F7GJ32 F7GJ32 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000048484.1|UniProtKB=A0A5F8GZW2 A0A5F8GZW2 PTHR24390:SF250 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 763 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000012338.2|UniProtKB=F7E2D8 F7E2D8 HOXB5 PTHR45659:SF2 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-B5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000022841.3|UniProtKB=H9H9N1 H9H9N1 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008222.3|UniProtKB=F6ZYC6 F6ZYC6 ZACN PTHR18945:SF912 NEUROTRANSMITTER GATED ION CHANNEL LIGAND-GATED CATION CHANNEL ZACN signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276 chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic transmission, cholinergic#GO:0007271;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000042620.1|UniProtKB=A0A5F8G7A1 A0A5F8G7A1 LMO3 PTHR45787:SF7 LD11652P LIM DOMAIN ONLY PROTEIN 3 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000046883.1|UniProtKB=F7E8V4 F7E8V4 LOC100618376 PTHR26450:SF195 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002889.4|UniProtKB=F7B602 F7B602 MAN2B2 PTHR11607:SF28 ALPHA-MANNOSIDASE EPIDIDYMIS-SPECIFIC ALPHA-MANNOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;lysosome#GO:0005764;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 hydrolase#PC00121;glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000009270.4|UniProtKB=F7DA32 F7DA32 SF3A1 PTHR15316:SF1 SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED SPLICING FACTOR 3A SUBUNIT 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;U2-type prespliceosome#GO:0071004;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000015634.4|UniProtKB=A0A5F8H451 A0A5F8H451 GLT1D1 PTHR46660:SF2 FAMILY NOT NAMED GLYCOSYLTRANSFERASE 1 DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000024428.2|UniProtKB=F7FHN1 F7FHN1 PTHR34034:SF1 PROTEIN FAM180A-RELATED PROTEIN FAM180B MONDO|Ensembl=ENSMODG00000003536.4|UniProtKB=F7GBR9 F7GBR9 SAP30 PTHR13286:SF7 SAP30 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP30 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000006875.5|UniProtKB=F6PWI0 F6PWI0 USP31 PTHR21646:SF44 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 31 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000004701.3|UniProtKB=F6TQ76 F6TQ76 IGBP1 PTHR10933:SF9 IMMUNOGLOBULIN-BINDING PROTEIN 1 IMMUNOGLOBULIN BINDING PROTEIN 1 enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 biological regulation#GO:0065007;signaling#GO:0023052;TOR signaling#GO:0031929;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000009446.4|UniProtKB=A0A5F8HJ54 A0A5F8HJ54 LGR4 PTHR24372:SF67 GLYCOPROTEIN HORMONE RECEPTOR LEUCINE-RICH REPEAT-CONTAINING G PROTEIN-COUPLED RECEPTOR 4 molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;positive regulation of canonical Wnt signaling pathway#GO:0090263;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;hormone-mediated signaling pathway#GO:0009755;response to hormone#GO:0009725;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;positive regulation of Wnt signaling pathway#GO:0030177;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000007952.4|UniProtKB=F7G8T8 F7G8T8 ZBTB3 PTHR24394:SF19 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 3 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006466.3|UniProtKB=F6XK92 F6XK92 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000046927.1|UniProtKB=A0A5F8HDZ4 A0A5F8HDZ4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000005082.3|UniProtKB=F7A4G6 F7A4G6 NDUFAF5 PTHR13090:SF1 ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000009715.4|UniProtKB=F6XT65 F6XT65 MAP2K1 PTHR48013:SF38 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1 protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>MKK1#P01369;T cell activation#P00053>MEK#P01312;Integrin signalling pathway#P00034>ERK#P00907;EGF receptor signaling pathway#P00018>MEK1-2#P00559;FGF signaling pathway#P00021>MEK1-2#P00642;VEGF signaling pathway#P00056>MEK#P01402;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891;B cell activation#P00010>MEK#P00383;Integrin signalling pathway#P00034>MEK#P00925;Endothelin signaling pathway#P00019>MEK#P00572;PDGF signaling pathway#P00047>MEK#P01162;Ras Pathway#P04393>MEK#P04557;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>MEK#P05926 MONDO|Ensembl=ENSMODG00000002061.4|UniProtKB=F6W852 F6W852 ANTXRL PTHR16059:SF16 ANTHRAX TOXIN RECEPTOR ANTHRAX TOXIN RECEPTOR-LIKE molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000007023.4|UniProtKB=F6UX55 F6UX55 RGP1 PTHR12507:SF3 REDUCED GROWTH PHENOTYPE 1 RGP1, YEAST -RELATED RAB6A-GEF COMPLEX PARTNER PROTEIN 2 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147 membrane#GO:0016020;cytoplasm#GO:0005737;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000036540.1|UniProtKB=A0A5F8GZ55 A0A5F8GZ55 FOXI3 PTHR11829:SF310 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN I3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000013406.4|UniProtKB=F7CP25 F7CP25 ADIPOQ PTHR15427:SF20 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER ADIPONECTIN receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;hormone activity#GO:0005179 biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 Gonadotropin-releasing hormone receptor pathway#P06664>Adiponectin#P06761 MONDO|Ensembl=ENSMODG00000006256.4|UniProtKB=A0A5F8GB34 A0A5F8GB34 SCUBE1 PTHR24046:SF4 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 1 cellular developmental process#GO:0048869;developmental process#GO:0032502;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;smoothened signaling pathway#GO:0007224;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell development#GO:0048468;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;response to growth factor#GO:0070848;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;muscle cell differentiation#GO:0042692;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;muscle cell development#GO:0055001;response to endogenous stimulus#GO:0009719 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 extracellular matrix glycoprotein#PC00100 MONDO|Ensembl=ENSMODG00000042032.1|UniProtKB=K7E0Y1 K7E0Y1 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000028925.2|UniProtKB=K7E575 K7E575 PTHR43884:SF11 ACYL-COA DEHYDROGENASE VERY LONG-CHAIN ACYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824 cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000006207.4|UniProtKB=F6ZSR7 F6ZSR7 TMC7 PTHR23302:SF42 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 7 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;gated channel activity#GO:0022836;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000008445.4|UniProtKB=F7GF19 F7GF19 RTN1 PTHR45799:SF5 RETICULON-LIKE PROTEIN RETICULON-1 endoplasmic reticulum tubular network organization#GO:0071786;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum membrane organization#GO:0090158 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000007539.4|UniProtKB=F7GAY3 F7GAY3 PTHR14352:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 7 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 7 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 cell cycle process#GO:0022402;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;organelle#GO:0043226;HAUS complex#GO:0070652;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000024706.2|UniProtKB=F7AEU9 F7AEU9 PTHR24356:SF221 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 38 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;establishment or maintenance of cell polarity#GO:0007163 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000025600.3|UniProtKB=F6QC96 F6QC96 SREK1IP1 PTHR31437:SF1 SREK1IP1 FAMILY MEMBER PROTEIN SREK1IP1 MONDO|Ensembl=ENSMODG00000024492.2|UniProtKB=F7E3H1 F7E3H1 EDDM3B PTHR16788:SF0 EPIDIDYMAL SECRETORY PROTEIN E3 ALPHA EPIDIDYMAL SECRETORY PROTEIN E3-BETA MONDO|Ensembl=ENSMODG00000015753.3|UniProtKB=A0A5F8GKD5 A0A5F8GKD5 MAPRE3 PTHR10623:SF10 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER MICROTUBULE-ASSOCIATED PROTEIN RP_EB FAMILY MEMBER 3 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;regulation of microtubule-based process#GO:0032886;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;protein localization to microtubule cytoskeleton#GO:0072698;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;spindle assembly#GO:0051225;intracellular protein localization#GO:0008104;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059 intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;supramolecular fiber#GO:0099512;cytoplasmic microtubule#GO:0005881;microtubule end#GO:1990752;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000037455.1|UniProtKB=A0A5F8GA29 A0A5F8GA29 PTHR10257:SF123 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;protein phosphatase regulator activity#GO:0019888;phosphatase activator activity#GO:0019211;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;chromosome organization#GO:0051276;meiotic sister chromatid cohesion#GO:0051177;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 MONDO|Ensembl=ENSMODG00000009425.2|UniProtKB=F7BLE2 F7BLE2 CLN6 PTHR16244:SF2 CEROID-LIPOFUSCINOSIS NEURONAL PROTEIN 6 CEROID-LIPOFUSCINOSIS NEURONAL PROTEIN 6 endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;membrane microdomain#GO:0098857;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle lumen#GO:0043233;membrane raft#GO:0045121;vesicle#GO:0031982;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endosome#GO:0005768 MONDO|Ensembl=ENSMODG00000024031.2|UniProtKB=F7D3V8 F7D3V8 FAM187A PTHR32178:SF7 FAM187 IG-LIKE V-TYPE DOMAIN-CONTAINING PROTEIN FAM187A immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000010535.3|UniProtKB=F6ZIY5 F6ZIY5 PTHR21053:SF2 TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL transcription regulator activity#GO:0140110;transcription elongation factor activity#GO:0003711 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoid#GO:0009295;mitochondrial nucleoid#GO:0042645;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000005458.4|UniProtKB=A0A5F8HDL8 A0A5F8HDL8 DYNC2I1 PTHR16022:SF0 WD REPEAT DOMAIN 60 CYTOPLASMIC DYNEIN 2 INTERMEDIATE CHAIN 1 binding#GO:0005488;protein binding#GO:0005515 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 catalytic complex#GO:1902494;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;spindle pole#GO:0000922;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;membraneless organelle#GO:0043228;cytoplasmic dynein complex#GO:0005868;ciliary base#GO:0097546;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000018804.4|UniProtKB=F6ZMD5 F6ZMD5 ENSA PTHR10358:SF21 ENDOSULFINE ALPHA-ENDOSULFINE phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000015166.4|UniProtKB=A0A5F8GDR1 A0A5F8GDR1 OSBPL10 PTHR10972:SF47 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 10 alcohol binding#GO:0043178;cholesterol binding#GO:0015485;lipid binding#GO:0008289;steroid binding#GO:0005496;binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934 membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000005025.3|UniProtKB=F7ER19 F7ER19 PTHR21399:SF0 CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN METHYLOSOME SUBUNIT PICLN cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;spliceosomal snRNP assembly#GO:0000387;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 MONDO|Ensembl=ENSMODG00000001926.5|UniProtKB=A0A5F8GVF6 A0A5F8GVF6 NUAK1 PTHR24343:SF350 SERINE/THREONINE KINASE NUAK FAMILY SNF1-LIKE KINASE 1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000001638.4|UniProtKB=A0A5F8H4P3 A0A5F8H4P3 SEC14L1 PTHR23324:SF51 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of innate immune response#GO:0045088;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;regulation of signaling#GO:0023051;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000015856.4|UniProtKB=F7F0D0 F7F0D0 MDFIC PTHR15304:SF0 MYOD FAMILY INHIBITOR MYOD FAMILY INHIBITOR DOMAIN-CONTAINING PROTEIN regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of JNK cascade#GO:0046328;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000001324.3|UniProtKB=F7FWF2 F7FWF2 PDAP1 PTHR22055:SF0 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000048515.1|UniProtKB=A0A5F8H8P2 A0A5F8H8P2 SPATA2 PTHR15326:SF8 SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC SPERMATOGENESIS-ASSOCIATED PROTEIN 2 signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling receptor complex adaptor activity#GO:0030159 regulation of programmed cell death#GO:0043067;regulation of response to cytokine stimulus#GO:0060759;regulation of biological process#GO:0050789;regulation of response to external stimulus#GO:0032101;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;regulation of signaling#GO:0023051;regulation of cytokine-mediated signaling pathway#GO:0001959 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000022943.1|UniProtKB=F6PYR9 F6PYR9 LOC100020235 PTHR26450:SF411 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51A7 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015317.4|UniProtKB=F6VB03 F6VB03 BAG6 PTHR15204:SF0 LARGE PROLINE-RICH PROTEIN BAG6 LARGE PROLINE-RICH PROTEIN BAG6 modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;protein binding#GO:0005515 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000008902.4|UniProtKB=A0A5F8GRM2 A0A5F8GRM2 PTHR43377:SF13 BILIVERDIN REDUCTASE A BILIVERDIN REDUCTASE A oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000021414.2|UniProtKB=F7CBR3 F7CBR3 MC5R PTHR22750:SF5 G-PROTEIN COUPLED RECEPTOR MELANOCORTIN RECEPTOR 5 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000013744.4|UniProtKB=F6X7N5 F6X7N5 TAGLN PTHR47385:SF16 CALPONIN TRANSGELIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000017667.5|UniProtKB=F6YJB8 F6YJB8 YDJC PTHR31609:SF1 YDJC DEACETYLASE FAMILY MEMBER CARBOHYDRATE DEACETYLASE deacetylase activity#GO:0019213;catalytic activity#GO:0003824;deacylase activity#GO:0160215 MONDO|Ensembl=ENSMODG00000005791.4|UniProtKB=F6XFY4 F6XFY4 FRA10AC1 PTHR11567:SF25 ACID PHOSPHATASE-RELATED PROTEIN FRA10AC1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000008602.3|UniProtKB=F6PHE4 F6PHE4 PTHR12429:SF9 NEURALIZED E3 UBIQUITIN-PROTEIN LIGASE NEURL3 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;import into cell#GO:0098657;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;transport#GO:0006810;regulation of response to stimulus#GO:0048583;protein localization to organelle#GO:0033365;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;localization#GO:0051179;protein transport#GO:0015031;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000009865.4|UniProtKB=F6VV84 F6VV84 NPTN PTHR10075:SF108 BASIGIN RELATED NEUROPLASTIN cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000002899.4|UniProtKB=F7EEI2 F7EEI2 PTHR24376:SF210 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 721-RELATED gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000001007.4|UniProtKB=A0A5F8H8N2 A0A5F8H8N2 CD38 PTHR10912:SF5 ADP-RIBOSYL CYCLASE ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE 1 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 positive regulation of lymphocyte proliferation#GO:0050671;regulation of cell population proliferation#GO:0042127;positive regulation of lymphocyte activation#GO:0051251;regulation of leukocyte activation#GO:0002694;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of B cell proliferation#GO:0030890;regulation of lymphocyte activation#GO:0051249;positive regulation of leukocyte proliferation#GO:0070665;regulation of B cell proliferation#GO:0030888;positive regulation of leukocyte activation#GO:0002696;regulation of leukocyte proliferation#GO:0070663;positive regulation of mononuclear cell proliferation#GO:0032946;regulation of B cell activation#GO:0050864;positive regulation of immune system process#GO:0002684;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of lymphocyte proliferation#GO:0050670;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;regulation of multicellular organismal process#GO:0051239 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metabolite interconversion enzyme#PC00262;cyclase#PC00079 CCKR signaling map#P06959>CD38#P07204 MONDO|Ensembl=ENSMODG00000042488.1|UniProtKB=A0A5F8GB79 A0A5F8GB79 PTHR23232:SF179 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 8-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000000848.4|UniProtKB=A0A5F8GQJ0 A0A5F8GQJ0 ZRANB3 PTHR45766:SF3 DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697 replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000045568.1|UniProtKB=F6QZW6 F6QZW6 PTHR45635:SF13 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE 3 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000004075.4|UniProtKB=F6VW60 F6VW60 EI24 PTHR21389:SF0 P53 INDUCED PROTEIN ETOPOSIDE-INDUCED PROTEIN 2.4 HOMOLOG metabolic process#GO:0008152;autophagy#GO:0006914;cellular process#GO:0009987;catabolic process#GO:0009056;macroautophagy#GO:0016236;process utilizing autophagic mechanism#GO:0061919 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000014363.4|UniProtKB=F7GC63 F7GC63 SF3B3 PTHR10644:SF1 DNA REPAIR/RNA PROCESSING CPSF FAMILY SPLICING FACTOR 3B SUBUNIT 3 binding#GO:0005488;nucleic acid binding#GO:0003676;snRNA binding#GO:0017069;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA processing factor#PC00147;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000014405.3|UniProtKB=F6YM00 F6YM00 PTHR23138:SF94 RAN BINDING PROTEIN RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN nucleocytoplasmic transport#GO:0006913;transport#GO:0006810;intracellular transport#GO:0046907;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle envelope#GO:0031967 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017373.4|UniProtKB=F6VID8 F6VID8 RNF19B PTHR11685:SF109 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF19B protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 lysosome#GO:0005764;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000051204.1|UniProtKB=K7E135 K7E135 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000004404.4|UniProtKB=F6SVG1 F6SVG1 ARSG PTHR42693:SF42 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE G hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000010029.4|UniProtKB=F6TUK5 F6TUK5 MRM3 PTHR43191:SF2 RRNA METHYLTRANSFERASE 3, RRNA METHYLTRANSFERASE 3, MITOCHONDRIAL RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000015826.4|UniProtKB=F7FDW7 F7FDW7 CAV1 PTHR10844:SF18 CAVEOLIN CAVEOLIN-1 protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;transmembrane transporter binding#GO:0044325;protein kinase binding#GO:0019901 membrane organization#GO:0061024;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;negative regulation of cell population proliferation#GO:0008285;cellular component biogenesis#GO:0044085;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of cytosolic calcium ion concentration#GO:0051480;regulation of biological process#GO:0050789;membrane assembly#GO:0071709;cellular component organization#GO:0016043;intracellular monoatomic ion homeostasis#GO:0006873;negative regulation of biological process#GO:0048519;plasma membrane organization#GO:0007009;regulation of cell population proliferation#GO:0042127;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074 plasma membrane region#GO:0098590;endomembrane system#GO:0012505;perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;cytoplasm#GO:0005737;caveola#GO:0005901;membrane#GO:0016020;cell periphery#GO:0071944;sarcolemma#GO:0042383;cell junction#GO:0030054;Golgi apparatus#GO:0005794;membrane microdomain#GO:0098857;organelle#GO:0043226;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane raft#GO:0045121;vesicle#GO:0031982;plasma membrane raft#GO:0044853;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 Gonadotropin-releasing hormone receptor pathway#P06664>Caveolin-1#P06763;Integrin signalling pathway#P00034>Caveolin#P00918 MONDO|Ensembl=ENSMODG00000010767.3|UniProtKB=A0A5F8GIP0 A0A5F8GIP0 CDK16 PTHR24056:SF174 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 16 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 transport#GO:0006810;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;exocytosis#GO:0006887;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;secretion by cell#GO:0032940;secretion#GO:0046903;anatomical structure development#GO:0048856;localization#GO:0051179;cellular component organization#GO:0016043;cell development#GO:0048468;export from cell#GO:0140352;cell differentiation#GO:0030154;cell projection organization#GO:0030030 cell junction#GO:0030054;protein kinase complex#GO:1902911;transferase complex#GO:1990234;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;secretory vesicle#GO:0099503;nucleus#GO:0005634;presynapse#GO:0098793;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;exocytic vesicle#GO:0070382;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000007503.3|UniProtKB=Q2AB96 Q2AB96 T2R23 PTHR11394:SF58 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 7 taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037598.1|UniProtKB=K7E528 K7E528 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000005250.4|UniProtKB=A0A5F8GJ19 A0A5F8GJ19 RBMS1 PTHR48025:SF30 OS02G0815200 PROTEIN RIBONUCLEOPROTEIN, PTB BINDING 1 MONDO|Ensembl=ENSMODG00000014080.4|UniProtKB=A0A5F8G710 A0A5F8G710 CSNK2A2 PTHR24054:SF34 CASEIN KINASE II SUBUNIT ALPHA CASEIN KINASE II SUBUNIT ALPHA' kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 response to stress#GO:0006950;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of chromosome separation#GO:1905818;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;regulation of chromosome segregation#GO:0051983 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459 MONDO|Ensembl=ENSMODG00000013411.4|UniProtKB=A0A5F8HFB6 A0A5F8HFB6 CEP120 PTHR21574:SF0 CENTROSOMAL PROTEIN OF 120 KDA CENTROSOMAL PROTEIN OF 120 KDA cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;cellular process#GO:0009987;cell cycle process#GO:0022402 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000020370.4|UniProtKB=F7AB98 F7AB98 SPEF2 PTHR14919:SF1 KPL2-RELATED SPERM FLAGELLA AND CILIA-ASSOCIATED PROTEIN 2 male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cilium assembly#GO:0060271;cellular component organization#GO:0016043;sperm motility#GO:0097722;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;spermatid differentiation#GO:0048515;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000040367.1|UniProtKB=A0A5F8GHM2 A0A5F8GHM2 UQCRB PTHR12022:SF0 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 7 electron transport chain#GO:0022900;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex III#GO:0045275;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069 reductase#PC00198;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000006716.4|UniProtKB=F7CXT2 F7CXT2 BCL2L11 PTHR12044:SF9 BCL2 INTERACTING MEDIATOR OF CELL DEATH BCL-2-LIKE PROTEIN 11 biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;meiotic nuclear division#GO:0140013;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;cell death#GO:0008219;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;programmed cell death#GO:0012501;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;response to endoplasmic reticulum stress#GO:0034976;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;response to stress#GO:0006950;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;meiotic cell cycle#GO:0051321;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;apoptotic process#GO:0006915;regulation of programmed cell death#GO:0043067;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;nuclear division#GO:0000280 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 Apoptosis signaling pathway#P00006>Bim#P00325 MONDO|Ensembl=ENSMODG00000013582.4|UniProtKB=A0A5F8GD35 A0A5F8GD35 ZBTB47 PTHR24394:SF24 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 47 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000017300.3|UniProtKB=F6S4N8 F6S4N8 PAXX PTHR28586:SF1 PROTEIN PAXX PROTEIN PAXX primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 DNA repair complex#GO:1990391;nucleus#GO:0005634;site of double-strand break#GO:0035861;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromosome#GO:0005694;nonhomologous end joining complex#GO:0070419;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000003138.3|UniProtKB=A0A5F8GE82 A0A5F8GE82 PTHR24075:SF0 SEC63 DOMAIN-CONTAINING TRANSLOCATION PROTEIN SEC63 HOMOLOG RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting#GO:0006605;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;protein targeting to ER#GO:0045047;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;SRP-dependent cotranslational protein targeting to membrane#GO:0006614 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum membrane#GO:0030867;rough endoplasmic reticulum#GO:0005791;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010059.4|UniProtKB=H9H6D2 H9H6D2 DMRTC2 PTHR12322:SF130 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DM DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;sex differentiation#GO:0007548;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000048299.1|UniProtKB=A0A5F8HI59 A0A5F8HI59 PTHR40389:SF3 ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED IGE-BINDING PROTEIN MONDO|Ensembl=ENSMODG00000015006.4|UniProtKB=A0A5F8GI14 A0A5F8GI14 CPAMD8 PTHR11412:SF139 MACROGLOBULIN / COMPLEMENT C3 AND PZP-LIKE ALPHA-2-MACROGLOBULIN DOMAIN-CONTAINING PROTEIN 8 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;eye development#GO:0001654;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;sensory organ development#GO:0007423;developmental process#GO:0032502;multicellular organismal process#GO:0032501;visual system development#GO:0150063;sensory system development#GO:0048880 extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;extracellular region#GO:0005576;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000009206.2|UniProtKB=F6YZA3 F6YZA3 GNG8 PTHR13809:SF19 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-8 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 extrinsic component of membrane#GO:0019898;side of membrane#GO:0098552;extrinsic component of plasma membrane#GO:0019897;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 heterotrimeric G-protein#PC00117 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Enkephalin release#P05913>G-Protein (s)#P05977;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (i)#P05974;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;GABA-B receptor II signaling#P05731>Ggamma#P05754;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Dopamine receptor mediated signaling pathway#P05912>Ggamma#P05967;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436 MONDO|Ensembl=ENSMODG00000049673.1|UniProtKB=A0A5F8G9I6 A0A5F8G9I6 PTHR24031:SF221 RNA HELICASE EUKARYOTIC INITIATION FACTOR 4A-I translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181 protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;cytoplasmic stress granule#GO:0010494;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000007773.4|UniProtKB=A0A5F8H5V0 A0A5F8H5V0 SPTBN4 PTHR11915:SF232 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 4 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 axon development#GO:0061564;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;neuron projection morphogenesis#GO:0048812;central nervous system neuron differentiation#GO:0021953;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;system development#GO:0048731;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular process#GO:0009987;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;central nervous system development#GO:0007417;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409 cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000000690.4|UniProtKB=A0A5F8GJJ9 A0A5F8GJJ9 MGAT5 PTHR15075:SF5 ALPHA-MANNOSIDE BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE A transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000029330.2|UniProtKB=K7E4T0 K7E4T0 PTHR22748:SF23 AP ENDONUCLEASE EXODEOXYRIBONUCLEASE III endonuclease activity#GO:0004519;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;3'-5' exonuclease activity#GO:0008408;phosphoric diester hydrolase activity#GO:0008081;catalytic activity, acting on DNA#GO:0140097;phosphoric ester hydrolase activity#GO:0042578;DNA exonuclease activity#GO:0004529;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;DNA endonuclease activity#GO:0004520;exonuclease activity#GO:0004527 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000000609.3|UniProtKB=F6V743 F6V743 LOC100011343 PTHR21245:SF11 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Q RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of RNA catabolic process#GO:1902369;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;positive regulation of biological process#GO:0048518 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000008171.4|UniProtKB=F7E5A8 F7E5A8 AMPD3 PTHR11359:SF2 AMP DEAMINASE AMP DEAMINASE 3 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;IMP metabolic process#GO:0046040;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside phosphate biosynthetic process#GO:1901293;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126 deaminase#PC00088 Purine metabolism#P02769>5'-AMP Deaminase#P03117 MONDO|Ensembl=ENSMODG00000003944.4|UniProtKB=F7G9H4 F7G9H4 MAGT1 PTHR12692:SF2 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT MAGT1 magnesium ion transport#GO:0015693;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;transport#GO:0006810;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;establishment of localization#GO:0051234;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;monoatomic cation transmembrane transport#GO:0098655;biosynthetic process#GO:0009058;monoatomic ion transmembrane transport#GO:0034220;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;protein metabolic process#GO:0019538;monoatomic ion transport#GO:0006811;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000011410.4|UniProtKB=F6Q0T4 F6Q0T4 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014141.4|UniProtKB=F6XK41 F6XK41 CLIP3 PTHR18916:SF77 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 3 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cytoplasmic microtubule organization#GO:0031122;microtubule-based process#GO:0007017;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 cell cortex#GO:0005938;microtubule end#GO:1990752;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;cell periphery#GO:0071944;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000024882.3|UniProtKB=F6SIA6 F6SIA6 PTHR10271:SF28 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 5 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 response to other organism#GO:0051707;response to cytokine#GO:0034097;response to chemical#GO:0042221;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;antiviral innate immune response#GO:0140374;defense response to virus#GO:0051607;response to peptide#GO:1901652;response to virus#GO:0009615;immune system process#GO:0002376 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000006544.4|UniProtKB=F7BV76 F7BV76 FABP5 PTHR11955:SF58 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN 5 ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;organic acid binding#GO:0043177;fatty acid binding#GO:0005504;lipid binding#GO:0008289 monocarboxylic acid transport#GO:0015718;localization#GO:0051179;fatty acid transport#GO:0015908;establishment of localization#GO:0051234;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869;macromolecule localization#GO:0033036 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000042127.1|UniProtKB=F7GEF3 F7GEF3 OR52E4 PTHR26450:SF13 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E4 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012963.4|UniProtKB=F7DC68 F7DC68 SIAH1 PTHR45877:SF7 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 E3 UBIQUITIN-PROTEIN LIGASE SIAH1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;binding#GO:0005488;acyltransferase activity#GO:0016746;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 Wnt signaling pathway#P00057>SIAH-1#P01433;p53 pathway#P00059>Siah#G04696;p53 pathway feedback loops 2#P04398>SIAH-1#P04660;p53 pathway feedback loops 2#P04398>SIAH-1#G04711 MONDO|Ensembl=ENSMODG00000001268.2|UniProtKB=F7CIY7 F7CIY7 PTHR31816:SF3 MICOS COMPLEX SUBUNIT MIC13 MICOS COMPLEX SUBUNIT MIC13 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;mitochondrial membrane organization#GO:0007006 organelle envelope#GO:0031967;membrane protein complex#GO:0098796;organelle membrane contact site#GO:0044232;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000041888.1|UniProtKB=A0A5F8H6I5 A0A5F8H6I5 DCXR PTHR44252:SF1 D-ERYTHRULOSE REDUCTASE CARBONYL REDUCTASE [NADPH] 2 oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455 glucose metabolic process#GO:0006006;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;cellular process#GO:0009987 reductase#PC00198;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000045136.1|UniProtKB=A0A5F8GWN6 A0A5F8GWN6 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000037468.1|UniProtKB=A0A5F8H1J4 A0A5F8H1J4 PTHR22802:SF14 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER K binding#GO:0005488;molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000001734.4|UniProtKB=A0A5F8HJC4 A0A5F8HJC4 PIK3R2 PTHR10155:SF1 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cell surface receptor signaling pathway#GO:0007166;cellular response to insulin stimulus#GO:0032869;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;insulin receptor signaling pathway#GO:0008286;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to oxygen-containing compound#GO:1901700 catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898;membrane protein complex#GO:0098796;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 kinase modulator#PC00140 Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;PDGF signaling pathway#P00047>PI3K#P01168;Angiogenesis#P00005>PI3K#P00236;PI3 kinase pathway#P00048>p85#P01202;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;Integrin signalling pathway#P00034>PI3K#P00936;Axon guidance mediated by netrin#P00009>PI3K#P00363;VEGF signaling pathway#P00056>PI3K#P01413;T cell activation#P00053>PI3K#P01322;p53 pathway feedback loops 2#P04398>PI3K#P04661 MONDO|Ensembl=ENSMODG00000011490.5|UniProtKB=F6V2M7 F6V2M7 APBB3 PTHR14058:SF10 AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 3 binding#GO:0005488;peptide binding#GO:0042277 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Alzheimer disease-presenilin pathway#P00004>Fe65#P00126 MONDO|Ensembl=ENSMODG00000015798.3|UniProtKB=A0A5F8G5B6 A0A5F8G5B6 ULBP-like PTHR16675:SF64 MHC CLASS I-RELATED RETINOIC ACID EARLY TRANSCRIPT 1E signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;regulation of leukocyte mediated immunity#GO:0002703;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;cell killing#GO:0001906;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;regulation of cell killing#GO:0031341;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;biological process involved in interspecies interaction between organisms#GO:0044419;leukocyte mediated cytotoxicity#GO:0001909;natural killer cell mediated immunity#GO:0002228;regulation of biological process#GO:0050789;natural killer cell mediated cytotoxicity#GO:0042267;immune effector process#GO:0002252;defense response to other organism#GO:0098542;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000048121.1|UniProtKB=F6QSK0 F6QSK0 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000000788.3|UniProtKB=F6SSE6 F6SSE6 GADD45A PTHR10411:SF3 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 ALPHA molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311 positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of JNK cascade#GO:0046328;positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 p53 pathway#P00059>GADD45#G01575;PI3 kinase pathway#P00048>GADD45#G01544;p38 MAPK pathway#P05918>GADD45#P06044;p53 pathway#P00059>GADD45#P04626 MONDO|Ensembl=ENSMODG00000028176.2|UniProtKB=K7E3E6 K7E3E6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000036919.1|UniProtKB=A0A5F8H779 A0A5F8H779 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000049583.1|UniProtKB=K7E0G8 K7E0G8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000011441.3|UniProtKB=A0A5F8GFQ3 A0A5F8GFQ3 SIGLEC1 PTHR47243:SF1 SIALOADHESIN SIALOADHESIN protein binding#GO:0005515;binding#GO:0005488 transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898;biological process involved in symbiotic interaction#GO:0044403;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;biological process involved in interspecies interaction between organisms#GO:0044419;biological process involved in interaction with host#GO:0051701 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;late endosome#GO:0005770;plasma membrane#GO:0005886;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000009717.5|UniProtKB=A0A5F8H243 A0A5F8H243 LTBP3 PTHR24034:SF46 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 3 regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;response to transforming growth factor beta#GO:0071559;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000021305.5|UniProtKB=F7G3I5 F7G3I5 PIK3CA PTHR10048:SF107 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of cellular process#GO:0050794;cell motility#GO:0048870;phospholipid biosynthetic process#GO:0008654;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;phosphatidylinositol phosphate biosynthetic process#GO:0046854;lipid biosynthetic process#GO:0008610;cell migration#GO:0016477;glycerophospholipid metabolic process#GO:0006650;intracellular signaling cassette#GO:0141124;biosynthetic process#GO:0009058;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;signal transduction#GO:0007165;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474 transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 kinase#PC00137 Axon guidance mediated by netrin#P00009>PI3K#P00363;Integrin signalling pathway#P00034>PI3K#P00936;p53 pathway feedback loops 2#P04398>P110alpha#P04657;p53 pathway feedback loops 2#P04398>P110ALPHA#G04707;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>P110alpha#P04633;PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;Ras Pathway#P04393>PI3K#P04567;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Hypoxia response via HIF activation#P00030>PI3K#P00823;Interleukin signaling pathway#P00036>PI3K#P00990;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>p110alpha#G04694;PI3 kinase pathway#P00048>P110ACT#P01177;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>p110alpha#G04676;VEGF signaling pathway#P00056>PI3K#P01413;PI3 kinase pathway#P00048>p110#P01192;FGF signaling pathway#P00021>PI3K#P00640;B cell activation#P00010>PI3K#P00391;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;T cell activation#P00053>PI3K#P01322;EGF receptor signaling pathway#P00018>PI3K#P00557;Angiogenesis#P00005>PI3K#P00236;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>P110alpha#P04498 MONDO|Ensembl=ENSMODG00000024983.2|UniProtKB=F6XNT3 F6XNT3 SOX14 PTHR10270:SF107 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-14 sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;head development#GO:0060322;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;animal organ development#GO:0048513 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000013290.4|UniProtKB=F6ZK75 F6ZK75 DYNC1H1 PTHR10676:SF404 DYNEIN HEAVY CHAIN FAMILY PROTEIN CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1 catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;microtubule motor activity#GO:0003777 cytoskeleton-dependent intracellular transport#GO:0030705;axo-dendritic transport#GO:0008088;mitotic cell cycle process#GO:1903047;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;spindle organization#GO:0007051;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based movement#GO:0007018;cell motility#GO:0048870;mitotic cell cycle#GO:0000278;nuclear migration#GO:0007097;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;organelle localization#GO:0051640;axonal transport#GO:0098930;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;mitotic spindle organization#GO:0007052;cytoplasmic microtubule organization#GO:0031122;establishment of organelle localization#GO:0051656;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular localization#GO:0051641;cilium-dependent cell motility#GO:0060285;retrograde axonal transport#GO:0008090;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;microtubule-based transport#GO:0099111 protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoplasmic microtubule#GO:0005881;dynein complex#GO:0030286;cell cortex#GO:0005938;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cilium#GO:0005929;9+2 motile cilium#GO:0097729 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000042400.1|UniProtKB=A0A5F8HHD4 A0A5F8HHD4 ZSWIM3 PTHR31569:SF3 SWIM-TYPE DOMAIN-CONTAINING PROTEIN ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 3 MONDO|Ensembl=ENSMODG00000002632.4|UniProtKB=F7FUA5 F7FUA5 GNE PTHR18964:SF176 ROK (REPRESSOR, ORF, KINASE) FAMILY BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;isomerase activity#GO:0016853;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000017102.3|UniProtKB=F6V2Y7 F6V2Y7 ARID5B PTHR13964:SF37 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 5B binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000018065.4|UniProtKB=F7G485 F7G485 GRIK2 PTHR18966:SF38 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;sodium ion transmembrane transporter activity#GO:0015081;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;potassium ion transmembrane transporter activity#GO:0015079;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;signaling receptor activity#GO:0038023;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836 synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic signaling#GO:0099536;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537 sodium channel complex#GO:0034706;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cell junction#GO:0030054;transporter complex#GO:1990351;cation channel complex#GO:0034703;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;neuron to neuron synapse#GO:0098984;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA2#P01003;Ionotropic glutamate receptor pathway#P00037>KA#P01026;Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 MONDO|Ensembl=ENSMODG00000040286.1|UniProtKB=A0A5F8H3M0 A0A5F8H3M0 PTHR46890:SF56 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED OS06G0484800 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000057.4|UniProtKB=F6REF1 F6REF1 BPIFB4 PTHR46019:SF4 BPI FOLD-CONTAINING FAMILY B MEMBER 4-RELATED BPI FOLD-CONTAINING FAMILY B MEMBER 4 MONDO|Ensembl=ENSMODG00000010435.4|UniProtKB=F6YTK6 F6YTK6 EXOSC4 PTHR11953:SF0 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT RRP41 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;macromolecule catabolic process#GO:0009057;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;exoribonuclease#PC00099 MONDO|Ensembl=ENSMODG00000015416.4|UniProtKB=A0A5F8HHW9 A0A5F8HHW9 ENOX2 PTHR16001:SF7 ANGEL WING family ECTO-NOX DISULFIDE-THIOL EXCHANGER 2 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000007977.4|UniProtKB=F7D6B6 F7D6B6 CNTFR PTHR23036:SF21 CYTOKINE RECEPTOR CILIARY NEUROTROPHIC FACTOR RECEPTOR SUBUNIT ALPHA cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089 cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;cell surface receptor signaling pathway#GO:0007166 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001138.4|UniProtKB=F7A2S4 F7A2S4 RUSF1 PTHR12770:SF31 RUS1 FAMILY PROTEIN C16ORF58 RUS FAMILY MEMBER 1 MONDO|Ensembl=ENSMODG00000012470.4|UniProtKB=F6Q4J8 F6Q4J8 SBNO1 PTHR12706:SF8 STRAWBERRY NOTCH-RELATED PROTEIN STRAWBERRY NOTCH HOMOLOG 1 protein binding#GO:0005515;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;histone binding#GO:0042393;chromatin binding#GO:0003682 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000048820.1|UniProtKB=F7GG75 F7GG75 DNMT1 PTHR10629:SF61 CYTOSINE-SPECIFIC METHYLTRANSFERASE DNA (CYTOSINE-5)-METHYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;binding#GO:0005488;nucleic acid binding#GO:0003676;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;DNA binding#GO:0003677 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA methyltransferase#PC00013;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000004158.4|UniProtKB=A0A5F8GP42 A0A5F8GP42 ME3 PTHR23406:SF20 MALIC ENZYME-RELATED NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000004116.4|UniProtKB=F6VDX9 F6VDX9 MEX3D PTHR23285:SF3 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING PROTEIN MEX3D RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000006927.3|UniProtKB=F6PRF3 F6PRF3 DOHH PTHR12697:SF42 PBS LYASE HEAT-LIKE PROTEIN DEOXYHYPUSINE HYDROXYLASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 lyase#PC00144 MONDO|Ensembl=ENSMODG00000008055.4|UniProtKB=F6Z9K0 F6Z9K0 USP42 PTHR24006:SF727 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 42 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;regulation of biological process#GO:0050789;regulation of protein stability#GO:0031647;regulation of programmed cell death#GO:0043067 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000023148.3|UniProtKB=F6YGM5 F6YGM5 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020497.3|UniProtKB=A0A5F8HD06 A0A5F8HD06 NTS PTHR15356:SF0 NEUROTENSIN/NEUROMEDIN N NEUROTENSIN_NEUROMEDIN N signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 neuron projection#GO:0043005;presynapse#GO:0098793;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron projection terminus#GO:0044306;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;axon#GO:0030424;cell junction#GO:0030054;axon terminus#GO:0043679 MONDO|Ensembl=ENSMODG00000044092.1|UniProtKB=K7E180 K7E180 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000037732.1|UniProtKB=A0A5F8H934 A0A5F8H934 GSKIP PTHR12490:SF4 GSK3B-INTERACTING PROTEIN GSK3B-INTERACTING PROTEIN binding#GO:0005488;protein kinase A binding#GO:0051018;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000021266.4|UniProtKB=F6T2Y8 F6T2Y8 WWTR1 PTHR17616:SF6 YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER WW DOMAIN-CONTAINING TRANSCRIPTION REGULATOR PROTEIN 1 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 positive regulation of transcription by RNA polymerase II#GO:0045944;hippo signaling#GO:0035329;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of signaling#GO:0023051;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000018133.4|UniProtKB=F7DGR0 F7DGR0 NEPRO PTHR34761:SF1 NUCLEOLUS AND NEURAL PROGENITOR PROTEIN RIBONUCLEASE MRP SUBUNIT P64 regulation of Notch signaling pathway#GO:0008593;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of Notch signaling pathway#GO:0045747;positive regulation of response to stimulus#GO:0048584;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000009431.4|UniProtKB=A0A5F8HGQ2 A0A5F8HGQ2 ATP6V1H PTHR10698:SF7 V-TYPE PROTON ATPASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT H cellular localization#GO:0051641;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;intracellular monoatomic ion homeostasis#GO:0006873;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188;vesicle-mediated transport in synapse#GO:0099003;vesicle organization#GO:0016050;chemical homeostasis#GO:0048878;vesicle-mediated transport#GO:0016192;monoatomic cation transmembrane transport#GO:0098655;organelle organization#GO:0006996;monoatomic ion homeostasis#GO:0050801;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;homeostatic process#GO:0042592;proton transmembrane transport#GO:1902600;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;developmental process#GO:0032502;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;developmental maturation#GO:0021700;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cellular anatomical structure#GO:0110165;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000048816.1|UniProtKB=A0A5F8G5H2 A0A5F8G5H2 GEMIN2 PTHR12794:SF0 GEMIN2 GEM-ASSOCIATED PROTEIN 2 protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal snRNP assembly#GO:0000387;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;SMN complex#GO:0032797;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000017323.4|UniProtKB=F6WWJ4 F6WWJ4 EGFL6 PTHR24050:SF24 PA14 DOMAIN-CONTAINING PROTEIN EPIDERMAL GROWTH FACTOR-LIKE PROTEIN 6 MONDO|Ensembl=ENSMODG00000050535.1|UniProtKB=A0A5F8GH44 A0A5F8GH44 PTHR12021:SF27 THYMOSIN BETA THYMOSIN BETA-4-LIKE binding#GO:0005488;molecular sequestering activity#GO:0140313;actin monomer binding#GO:0003785;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein sequestering activity#GO:0140311;protein binding#GO:0005515 regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of locomotion#GO:0040012 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000006540.3|UniProtKB=F7BVJ4 F7BVJ4 GTF2H1 PTHR12856:SF0 TRANSCRIPTION INITIATION FACTOR IIH-RELATED GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 1 response to stimulus#GO:0050896;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;RNA metabolic process#GO:0016070;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleotide-excision repair#GO:0006289;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription factor TFIIH holo complex#GO:0005675;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;transcription factor TFIIH core complex#GO:0000439 general transcription factor#PC00259;RNA metabolism protein#PC00031 Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392;General transcription regulation#P00023>TFIIH complex#P00664 MONDO|Ensembl=ENSMODG00000021483.3|UniProtKB=F7G2Y7 F7G2Y7 USP14 PTHR43982:SF1 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14 cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;binding#GO:0005488;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;protein-containing complex binding#GO:0044877 negative regulation of biological process#GO:0048519;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of ERAD pathway#GO:1904292;negative regulation of proteasomal protein catabolic process#GO:1901799;regulation of protein catabolic process#GO:0042176;regulation of cellular response to stress#GO:0080135;negative regulation of catabolic process#GO:0009895;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of response to stimulus#GO:0048585;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of catabolic process#GO:0009894 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000011418.4|UniProtKB=F6RL13 F6RL13 MEIOC PTHR33861:SF3 PROTEIN CBG18333 MEIOSIS-SPECIFIC COILED-COIL DOMAIN-CONTAINING PROTEIN MEIOC nuclear division#GO:0000280;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;meiotic cell cycle#GO:0051321;negative regulation of RNA metabolic process#GO:0051253;cellular component organization or biogenesis#GO:0071840;regulation of mRNA metabolic process#GO:1903311;organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;male meiotic nuclear division#GO:0007140;mRNA stabilization#GO:0048255;meiosis I cell cycle process#GO:0061982;regulation of RNA stability#GO:0043487;sexual reproduction#GO:0019953;positive regulation of biosynthetic process#GO:0009891;organelle fission#GO:0048285;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;multicellular organismal reproductive process#GO:0048609;cell cycle#GO:0007049;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;meiotic nuclear division#GO:0140013;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;male gamete generation#GO:0048232;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000025535.2|UniProtKB=F6V1G4 F6V1G4 OVCH2 PTHR24251:SF16 OVOCHYMASE-RELATED OVOCHYMASE-2 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000005504.3|UniProtKB=F7GFR3 F7GFR3 OVOL2 PTHR10032:SF193 ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS TRANSCRIPTION FACTOR OVO-LIKE 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;epidermis development#GO:0008544;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000009838.4|UniProtKB=F6WAR3 F6WAR3 DENND4A PTHR12296:SF16 DENN DOMAIN-CONTAINING PROTEIN 4 C-MYC PROMOTER-BINDING PROTEIN enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000007700.4|UniProtKB=A0A5F8HK78 A0A5F8HK78 IKBIP PTHR21734:SF11 INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE-INTERACTING PROTEIN INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE-INTERACTING PROTEIN MONDO|Ensembl=ENSMODG00000018390.5|UniProtKB=A0A5F8HAH0 A0A5F8HAH0 KDM5A PTHR10694:SF17 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 5A dioxygenase activity#GO:0051213;histone modifying activity#GO:0140993;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein demethylase activity#GO:0140457;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000016016.4|UniProtKB=F6UW32 F6UW32 PTHR12546:SF34 FER-1-LIKE FER-1-LIKE PROTEIN 5 cellular process#GO:0009987;membrane fusion#GO:0061025;response to stress#GO:0006950;response to wounding#GO:0009611;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;muscle structure development#GO:0061061;animal gross anatomical part developmental process#GO:0160108;wound healing#GO:0042060;plasma membrane organization#GO:0007009;anatomical structure development#GO:0048856 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000047727.1|UniProtKB=A0A5F8HBT0 A0A5F8HBT0 PTHR24384:SF261 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 719 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000015185.4|UniProtKB=F7BW30 F7BW30 PABIR3 PTHR22227:SF3 FAMILY WITH SEQUENCE SIMILARITY 122B ISOFORM X1 PABIR FAMILY MEMBER 1 enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208;protein serine/threonine phosphatase inhibitor activity#GO:0004865;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of biological process#GO:0050789;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of protein metabolic process#GO:0051247;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of metabolic process#GO:0009893 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000011367.4|UniProtKB=F6SPY8 F6SPY8 SLC10A1 PTHR10361:SF40 SODIUM-BILE ACID COTRANSPORTER HEPATIC SODIUM_BILE ACID COTRANSPORTER monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;solute:sodium symporter activity#GO:0015370;bile acid transmembrane transporter activity#GO:0015125;monoatomic cation transmembrane transporter activity#GO:0008324;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293 macromolecule localization#GO:0033036;lipid transport#GO:0006869;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;bile acid and bile salt transport#GO:0015721;lipid localization#GO:0010876;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000004747.3|UniProtKB=F6XJ52 F6XJ52 SNX29 PTHR47194:SF4 SORTING NEXIN-29-RELATED SORTING NEXIN-29 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000016494.4|UniProtKB=F6WHV8 F6WHV8 PAPSS2 PTHR11055:SF16 BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribose phosphate biosynthetic process#GO:0046390;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163 Sulfate assimilation#P02778>Sulfate adenylyltransferase#P03167 MONDO|Ensembl=ENSMODG00000012106.4|UniProtKB=F7FUE2 F7FUE2 ZMYND10 PTHR13244:SF7 ZINC FINGER MYND DOMAIN CONTAINING PROTEIN 10 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 10 protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;inner dynein arm assembly#GO:0036159;organelle assembly#GO:0070925;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;outer dynein arm assembly#GO:0036158;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;centriolar satellite#GO:0034451;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000008403.4|UniProtKB=F7BV02 F7BV02 RAB43 PTHR24073:SF653 DRAB5-RELATED RAS-RELATED PROTEIN RAB-43 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000006838.5|UniProtKB=F7C8D9 F7C8D9 NAE1 PTHR10953:SF29 UBIQUITIN-ACTIVATING ENZYME E1 NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782 post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000002785.1|UniProtKB=F6YGB7 F6YGB7 PDF PTHR10458:SF2 PEPTIDE DEFORMYLASE PEPTIDE DEFORMYLASE, MITOCHONDRIAL membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000041078.1|UniProtKB=F6YEH3 F6YEH3 LOC100010487 PTHR45635:SF13 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE 3 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000013490.1|UniProtKB=F7F8U1 F7F8U1 MED29 PTHR28314:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000023202.1|UniProtKB=F7EU36 F7EU36 LOC100016601 PTHR11937:SF590 ACTIN ACTIN, BETA structural molecule activity#GO:0005198;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;structural constituent of cytoskeleton#GO:0005200;kinase binding#GO:0019900;binding#GO:0005488;structural constituent of synapse#GO:0098918;protein binding#GO:0005515 axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731 actin cytoskeleton#GO:0015629;cell projection#GO:0042995;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;supramolecular fiber#GO:0099512;acetyltransferase complex#GO:1902493;neuron projection#GO:0043005;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;NuA4 histone acetyltransferase complex#GO:0035267;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;actin filament#GO:0005884;histone acetyltransferase complex#GO:0000123;cell junction#GO:0030054;chromosome#GO:0005694;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;H4 histone acetyltransferase complex#GO:1902562;transferase complex#GO:1990234;cytoskeleton#GO:0005856;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 actin and actin related protein#PC00039 Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Cadherin signaling pathway#P00012>F-actin#P00470 MONDO|Ensembl=ENSMODG00000014148.4|UniProtKB=K7E1G6 K7E1G6 AKR1B1 PTHR11732:SF294 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER B1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 reductase#PC00198;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000000906.5|UniProtKB=F7A701 F7A701 COMTD1 PTHR10509:SF14 O-METHYLTRANSFERASE-RELATED CATECHOL O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000028157.2|UniProtKB=K7E009 K7E009 PTHR24377:SF710 IP01015P-RELATED ZINC FINGER PROTEIN 181-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008248.3|UniProtKB=F6ZXE4 F6ZXE4 IRAG1 PTHR15352:SF2 LYMPHOID-RESTRICTED MEMBRANE PROTEIN, JAW1 INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR ASSOCIATED 1 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000011445.5|UniProtKB=F6Q0U8 F6Q0U8 UBQLN3 PTHR10677:SF4 UBIQUILIN UBIQUILIN-3 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000028050.2|UniProtKB=K7E2S5 K7E2S5 RD3L PTHR28489:SF3 RENTINAL DEGENERATION 3-LIKE PROTEIN RD3-LIKE MONDO|Ensembl=ENSMODG00000006795.4|UniProtKB=F6PGZ4 F6PGZ4 SLC35E2B PTHR11132:SF521 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E2A-RELATED active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000037296.1|UniProtKB=A0A5F8G8J0 A0A5F8G8J0 LOC100020266 PTHR48002:SF21 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010689.4|UniProtKB=F7C0Q3 F7C0Q3 LOC100018308 PTHR20913:SF11 TBC1 DOMAIN FAMILY MEMBER 20/GTPASE TBC1 DOMAIN FAMILY MEMBER 20 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Golgi organization#GO:0007030;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular localization#GO:0051641;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000028510.2|UniProtKB=K7E3C6 K7E3C6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001425.3|UniProtKB=F7BCQ9 F7BCQ9 PTHR13156:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904 respiratory chain complex I#GO:0045271;organelle membrane#GO:0031090;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000011434.5|UniProtKB=A0A5F8HF84 A0A5F8HF84 NOLC1 PTHR23216:SF2 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000014336.3|UniProtKB=A0A5F8GM49 A0A5F8GM49 MODO-UK PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of leukocyte mediated cytotoxicity#GO:0001910;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000014416.4|UniProtKB=A0A5F8HK13 A0A5F8HK13 CHCHD3 PTHR21588:SF18 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 6 MICOS COMPLEX SUBUNIT MIC19 cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;mitochondrial membrane organization#GO:0007006;cellular component organization#GO:0016043;organelle organization#GO:0006996;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743 MONDO|Ensembl=ENSMODG00000025116.2|UniProtKB=F6R2W6 F6R2W6 PTHR24103:SF676 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000003701.3|UniProtKB=F7FAA1 F7FAA1 POLG2 PTHR10745:SF8 GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2 DNA POLYMERASE SUBUNIT GAMMA-2 ligase activity#GO:0016874;enzyme activator activity#GO:0008047;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;catalytic activity, acting on RNA#GO:0140098;molecular function activator activity#GO:0140677;catalytic activity, acting on a tRNA#GO:0140101;enzyme regulator activity#GO:0030234 tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA metabolic process#GO:0006399;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;DNA-templated DNA replication#GO:0006261;mitochondrial DNA metabolic process#GO:0032042 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000020970.4|UniProtKB=F6S6N9 F6S6N9 LCA5L PTHR16650:SF9 C21ORF13-RELATED LEBERCILIN-LIKE PROTEIN microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000015987.3|UniProtKB=F7EZD6 F7EZD6 CPO PTHR11705:SF19 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE O hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000024689.2|UniProtKB=F7FDD3 F7FDD3 KLHL25 PTHR24410:SF10 HL07962P-RELATED KELCH-LIKE PROTEIN 25 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 regulation of cellular process#GO:0050794;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;positive regulation of metabolic process#GO:0009893;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of lipid metabolic process#GO:0019216;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul3-RING ubiquitin ligase complex#GO:0031463;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000018104.4|UniProtKB=A0A5F8GQV9 A0A5F8GQV9 SLC9C1 PTHR10110:SF87 SODIUM/HYDROGEN EXCHANGER SOLUTE CARRIER FAMILY 9 MEMBER C1 potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000039320.1|UniProtKB=A0A5F8GNQ2 A0A5F8GNQ2 PTHR45913:SF21 EPM2A-INTERACTING PROTEIN 1 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 2-LIKE MONDO|Ensembl=ENSMODG00000008461.2|UniProtKB=F7GEW2 F7GEW2 OTOS PTHR35073:SF1 OTOSPIRALIN OTOSPIRALIN nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605 MONDO|Ensembl=ENSMODG00000043387.1|UniProtKB=A0A5F8GUU7 A0A5F8GUU7 C11orf58 PTHR22175:SF0 SMALL ACIDIC PROTEIN-RELATED SMALL ACIDIC PROTEIN nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000020784.3|UniProtKB=F6YKG9 F6YKG9 BMP3 PTHR11848:SF144 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 3 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000015983.4|UniProtKB=F7EZK8 F7EZK8 PTHR23159:SF16 CENTROSOMAL PROTEIN 2 CILIARY ROOTLET COILED-COIL PROTEIN 2 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000008150.2|UniProtKB=F7ELI3 F7ELI3 DYNLRB2 PTHR10779:SF31 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 2 binding#GO:0005488;protein binding#GO:0005515 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;dynein complex#GO:0030286;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000023781.1|UniProtKB=F6X5P3 F6X5P3 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000565.4|UniProtKB=F6X4W6 F6X4W6 NIPA2 PTHR12570:SF1 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED MAGNESIUM TRANSPORTER NIPA2 magnesium ion transport#GO:0015693;transport#GO:0006810;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000003490.4|UniProtKB=F7CSL4 F7CSL4 PLBD2 PTHR12370:SF3 N-TERMINAL NUCLEOPHILE (NTN) HYDROLASE AMINOPEPTIDASE PLBD2-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000017174.3|UniProtKB=F6QD11 F6QD11 CLDN19 PTHR12002:SF27 CLAUDIN CLAUDIN-19 protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632;binding#GO:0005488;cell adhesion mediator activity#GO:0098631;paracellular tight junction channel activity#GO:0160187;cell adhesion molecule binding#GO:0050839;transporter activity#GO:0005215 epithelium development#GO:0060429;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;tissue development#GO:0009888;retina development in camera-type eye#GO:0060041;cellular component biogenesis#GO:0044085;sensory system development#GO:0048880;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;paracellular transport#GO:0160184;establishment of localization#GO:0051234;animal organ development#GO:0048513;sensory organ development#GO:0007423;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;transport#GO:0006810;cell junction organization#GO:0034330;visual system development#GO:0150063;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108 bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;apical junction complex#GO:0043296 cell junction protein#PC00070;tight junction#PC00214 MONDO|Ensembl=ENSMODG00000051319.1|UniProtKB=A0A5F8H066 A0A5F8H066 PTHR35252:SF1 RETINITIS PIGMENTOSA 9 PROTEIN RETINITIS PIGMENTOSA 9 PROTEIN MONDO|Ensembl=ENSMODG00000009910.4|UniProtKB=F6RU58 F6RU58 CCDC120 PTHR16093:SF5 COILED-COIL DOMAIN-CONTAINING PROTEIN 120 FAMILY MEMBER COILED-COIL DOMAIN-CONTAINING PROTEIN 120 MONDO|Ensembl=ENSMODG00000013748.4|UniProtKB=A0A5F8GQJ6 A0A5F8GQJ6 LUC7L2 PTHR12375:SF28 RNA-BINDING PROTEIN LUC7-RELATED RNA-BINDING PROTEIN LUC7-LIKE 2-RELATED mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA splice site recognition#GO:0006376;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398 nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681 MONDO|Ensembl=ENSMODG00000001700.4|UniProtKB=A0A5F8GXL4 A0A5F8GXL4 AGMO PTHR21624:SF1 STEROL DESATURASE-RELATED PROTEIN ALKYLGLYCEROL MONOOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000020573.4|UniProtKB=F7A1R1 F7A1R1 PHOX2B PTHR24329:SF301 HOMEOBOX PROTEIN ARISTALESS PAIRED MESODERM HOMEOBOX PROTEIN 2B DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;cell development#GO:0048468;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000009578.3|UniProtKB=A0A5F8GEW8 A0A5F8GEW8 SMYD1 PTHR12197:SF184 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD HISTONE-LYSINE N-METHYLTRANSFERASE SMYD1 lysine N-methyltransferase activity#GO:0016278;histone H3K4 methyltransferase activity#GO:0042800;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276 developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;animal organ development#GO:0048513;negative regulation of macromolecule biosynthetic process#GO:0010558;heart development#GO:0007507;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;circulatory system development#GO:0072359 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000019716.4|UniProtKB=F7AP18 F7AP18 TENT2 PTHR12271:SF140 POLY A POLYMERASE CID PAP -RELATED POLY(A) RNA POLYMERASE GLD2 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779 post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA destabilization#GO:0061157;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;RNA 3'-end processing#GO:0031123;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA processing#GO:0006397;mRNA catabolic process#GO:0006402;RNA processing#GO:0006396;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;modification-dependent macromolecule catabolic process#GO:0043632;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892 nucleotidyltransferase#PC00174 MONDO|Ensembl=ENSMODG00000006929.4|UniProtKB=F6PR04 F6PR04 WDR64 PTHR44324:SF2 WD40 REPEAT DOMAIN 95 WD REPEAT-CONTAINING PROTEIN 64 MONDO|Ensembl=ENSMODG00000005103.3|UniProtKB=A0A5F8H2U6 A0A5F8H2U6 CD101 PTHR12207:SF25 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 2 membrane#GO:0016020;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000006277.4|UniProtKB=F7FDH1 F7FDH1 NAPB PTHR13768:SF12 SOLUBLE NSF ATTACHMENT PROTEIN SNAP BETA-SOLUBLE NSF ATTACHMENT PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;protein-containing complex disassembly#GO:0032984;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;localization#GO:0051179;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component disassembly#GO:0022411;cellular localization#GO:0051641;protein transport#GO:0015031;vesicle-mediated transport#GO:0016192;synaptic transmission, glutamatergic#GO:0035249;synaptic signaling#GO:0099536;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;intracellular protein transport#GO:0006886 membrane#GO:0016020;neuron projection#GO:0043005;presynapse#GO:0098793;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cell junction#GO:0030054;axon terminus#GO:0043679;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;synapse#GO:0045202;plasma membrane bounded cell projection#GO:0120025;terminal bouton#GO:0043195;distal axon#GO:0150034;neuron projection terminus#GO:0044306;cell projection#GO:0042995;axon#GO:0030424;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000019186.4|UniProtKB=A0A5F8GL69 A0A5F8GL69 EXOC6B PTHR12702:SF3 SEC15 EXOCYST COMPLEX COMPONENT 6B transport#GO:0006810;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;exocytosis#GO:0006887;secretion by cell#GO:0032940;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000007829.4|UniProtKB=A0A5F8GYH8 A0A5F8GYH8 AURKB PTHR24350:SF4 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE B protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017 intracellular organelle#GO:0043229;microtubule#GO:0005874;spindle microtubule#GO:0005876;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;spindle pole#GO:0000922;chromosome#GO:0005694;midbody#GO:0030496;kinetochore#GO:0000776;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000010637.4|UniProtKB=F7D4X6 F7D4X6 CAB39 PTHR10182:SF11 CALCIUM-BINDING PROTEIN 39-RELATED CALCIUM-BINDING PROTEIN 39 kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 MONDO|Ensembl=ENSMODG00000043555.1|UniProtKB=A0A5F8H6X1 A0A5F8H6X1 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008348.4|UniProtKB=F7EKN3 F7EKN3 USP43 PTHR21646:SF20 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 43 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000020982.4|UniProtKB=A0A5F8G6H1 A0A5F8G6H1 DYRK1A PTHR24058:SF121 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1A transcription coactivator activity#GO:0003713;catalytic activity, acting on a protein#GO:0140096;transcription coregulator activity#GO:0003712;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000002345.4|UniProtKB=F7GLS3 F7GLS3 TBC1D8B PTHR22957:SF320 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 8B enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 system process#GO:0003008;multicellular organismal process#GO:0032501;renal system process#GO:0003014 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000028514.2|UniProtKB=F7CGX6 F7CGX6 VHL PTHR15160:SF17 VON HIPPEL-LINDAU PROTEIN VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR enzyme-substrate adaptor activity#GO:0140767;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;regulation of nucleobase-containing compound metabolic process#GO:0019219;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Hypoxia response via HIF activation#P00030>VHL#P00816 MONDO|Ensembl=ENSMODG00000002895.3|UniProtKB=F6PQE0 F6PQE0 TMEM17 PTHR13531:SF14 GEO07735P1-RELATED-RELATED TRANSMEMBRANE PROTEIN 17 non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;ciliary transition zone#GO:0035869 MONDO|Ensembl=ENSMODG00000012404.3|UniProtKB=F6PMQ0 F6PMQ0 PLPP7 PTHR14969:SF17 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE INACTIVE PHOSPHOLIPID PHOSPHATASE 7 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;dephosphorylation#GO:0016311;lipid modification#GO:0030258 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane#GO:0016020;organelle envelope#GO:0031967;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000003043.3|UniProtKB=F6Q0D9 F6Q0D9 LTB4R PTHR24230:SF51 G-PROTEIN COUPLED RECEPTOR LEUKOTRIENE B4 RECEPTOR 1 molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000020353.3|UniProtKB=F7FKA3 F7FKA3 DDB1 PTHR10644:SF27 DNA REPAIR/RNA PROCESSING CPSF FAMILY DNA DAMAGE-BINDING PROTEIN 1 response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;proteasomal protein catabolic process#GO:0010498;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152 chromosome#GO:0005694;site of double-strand break#GO:0035861;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000046643.1|UniProtKB=A0A5F8HGR4 A0A5F8HGR4 SMCO1 PTHR35979:SF1 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000006045.4|UniProtKB=K7E1P7 K7E1P7 PTHR13968:SF21 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING RALY-LIKE PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000000878.4|UniProtKB=A0A5F8G8R7 A0A5F8G8R7 SLC12A7 PTHR11827:SF47 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 7 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;chloride transmembrane transporter activity#GO:0015108;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transport#GO:0006813;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000013790.4|UniProtKB=A0A5F8H4W0 A0A5F8H4W0 GUK1 PTHR23117:SF13 GUANYLATE KINASE-RELATED GUANYLATE KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;nucleoside diphosphate metabolic process#GO:0009132;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;purine ribonucleoside diphosphate metabolic process#GO:0009179 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137;transferase#PC00220 De novo purine biosynthesis#P02738>Guanylate kinase#P02904 MONDO|Ensembl=ENSMODG00000046816.1|UniProtKB=A0A5F8GKY9 A0A5F8GKY9 HOXB1 PTHR45946:SF5 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN HOX-B1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000016047.4|UniProtKB=F6YU18 F6YU18 ANKRD23 PTHR24193:SF121 ANKYRIN REPEAT PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 23 MONDO|Ensembl=ENSMODG00000017391.3|UniProtKB=F6SL37 F6SL37 S100A16 PTHR11639:SF76 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A16 binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169 extracellular region#GO:0005576;perinuclear region of cytoplasm#GO:0048471;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000020404.4|UniProtKB=F7BZG2 F7BZG2 PTHR13723:SF189 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 12 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;external encapsulating structure organization#GO:0045229 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000019072.3|UniProtKB=F7FNP2 F7FNP2 PTHR24070:SF455 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY SMALL MONOMERIC GTPASE hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;EGF receptor signaling pathway#P00018>Ras#P00552;PDGF signaling pathway#P00047>Ras#P01154;Ras Pathway#P04393>Ras#P04547;Integrin signalling pathway#P00034>Ras#P00916;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;VEGF signaling pathway#P00056>Ras#P01411;Angiogenesis#P00005>Ras#P00238;p53 pathway feedback loops 2#P04398>Ras#P04651;FGF signaling pathway#P00021>Ras#P00633 MONDO|Ensembl=ENSMODG00000025786.3|UniProtKB=F7FSQ3 F7FSQ3 PTHR10462:SF26 GLYCOSYLTRANSFERASE-RELATED N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000014169.6|UniProtKB=A0A5F8HCW8 A0A5F8HCW8 RING1 PTHR46076:SF2 E3 UBIQUITIN-PROTEIN LIGASE RING1 / RING 2 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RING1 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;chromatin binding#GO:0003682;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;PcG protein complex#GO:0031519;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000006276.4|UniProtKB=F7FDN0 F7FDN0 DYNC2I2 PTHR12442:SF26 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 2 INTERMEDIATE CHAIN 2 binding#GO:0005488;protein binding#GO:0005515 organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782 cilium#GO:0005929;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;dynein complex#GO:0030286;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000037087.1|UniProtKB=A0A5F8H3W5 A0A5F8H3W5 LOC100030375 PTHR26454:SF165 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6T1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006668.4|UniProtKB=F7FTC5 F7FTC5 GPS2 PTHR22654:SF2 G PROTEIN PATHWAY SUPPRESSOR 2 G PROTEIN PATHWAY SUPPRESSOR 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000037857.1|UniProtKB=A0A5F8HD47 A0A5F8HD47 PTHR23232:SF179 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 8-LIKE transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000013484.4|UniProtKB=F7F939 F7F939 LOX PTHR45817:SF6 LYSYL OXIDASE-LIKE-RELATED PROTEIN-LYSINE 6-OXIDASE catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;extracellular structure organization#GO:0043062;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;extracellular matrix organization#GO:0030198;enzyme-linked receptor protein signaling pathway#GO:0007167;collagen fibril organization#GO:0030199;cell communication#GO:0007154;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 oxidoreductase#PC00176;oxidase#PC00175 MONDO|Ensembl=ENSMODG00000000429.3|UniProtKB=F6UTC5 F6UTC5 SLC32A1 PTHR48017:SF206 OS05G0424000 PROTEIN-RELATED VESICULAR INHIBITORY AMINO ACID TRANSPORTER glycine transmembrane transporter activity#GO:0015187;amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;neutral L-amino acid transmembrane transporter activity#GO:0015175 amino acid transport#GO:0006865;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;synaptic vesicle cycle#GO:0099504;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;glycine transport#GO:0015816;neutral amino acid transport#GO:0015804;cellular localization#GO:0051641;localization#GO:0051179 exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;neuron projection#GO:0043005;presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;neuron projection terminus#GO:0044306;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;organelle membrane#GO:0031090;somatodendritic compartment#GO:0036477;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506 MONDO|Ensembl=ENSMODG00000049524.1|UniProtKB=A0A5F8HAH2 A0A5F8HAH2 MYL12A PTHR23049:SF74 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 12A myosin binding#GO:0017022;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000020255.4|UniProtKB=F7CK00 F7CK00 RPS23 PTHR11652:SF14 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US12 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000024016.3|UniProtKB=F6YP19 F6YP19 PTHR14768:SF4 UPF0338 PROTEIN SYNAPSE DIFFERENTIATION-INDUCING GENE PROTEIN 1-LIKE organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000027479.2|UniProtKB=K7E539 K7E539 PTHR31635:SF196 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED MONDO|Ensembl=ENSMODG00000036715.1|UniProtKB=A0A5F8G652 A0A5F8G652 OXSM PTHR11712:SF362 POLYKETIDE SYNTHASE-RELATED 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283 MONDO|Ensembl=ENSMODG00000025546.2|UniProtKB=F6UJ69 F6UJ69 ELOVL6 PTHR11157:SF125 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 6 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000036655.1|UniProtKB=A0A5F8HH12 A0A5F8HH12 LOC103094545 PTHR24103:SF624 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF CONTAINING 54 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000016457.3|UniProtKB=F7A3G7 F7A3G7 LOC100017183 PTHR11984:SF56 CONNEXIN GAP JUNCTION GAMMA-3 PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 cell communication#GO:0007154;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell junction#GO:0030054;anchoring junction#GO:0070161 cell junction protein#PC00070;gap junction#PC00105 MONDO|Ensembl=ENSMODG00000014340.4|UniProtKB=A0A5F8GKA4 A0A5F8GKA4 SLC7A4 PTHR43243:SF108 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;amino acid transporter#PC00046 MONDO|Ensembl=ENSMODG00000012141.4|UniProtKB=F7DI08 F7DI08 ALDH1A3 PTHR11699:SF209 ALDEHYDE DEHYDROGENASE-RELATED RETINALDEHYDE DEHYDROGENASE 3 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;biosynthetic process#GO:0009058;biological regulation#GO:0065007;aldehyde catabolic process#GO:0046185;hormone metabolic process#GO:0042445;lipid biosynthetic process#GO:0008610;terpenoid biosynthetic process#GO:0016114;diterpenoid biosynthetic process#GO:0016102;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;monocarboxylic acid biosynthetic process#GO:0072330;regulation of hormone levels#GO:0010817;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;terpenoid metabolic process#GO:0006721;isoprenoid biosynthetic process#GO:0008299;oxoacid metabolic process#GO:0043436;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 MONDO|Ensembl=ENSMODG00000004509.3|UniProtKB=A0A5F8G954 A0A5F8G954 FBXO31 PTHR10706:SF161 F-BOX FAMILY PROTEIN F-BOX ONLY PROTEIN 31 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000005824.4|UniProtKB=F6U1X3 F6U1X3 METTL21EP PTHR14614:SF1 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN METHYLTRANSFERASE-LIKE PROTEIN 21E lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000005834.3|UniProtKB=F6U1R5 F6U1R5 LOC100619702 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013610.4|UniProtKB=F6VF55 F6VF55 DENND11 PTHR31017:SF2 LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED DENN DOMAIN-CONTAINING PROTEIN 11 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000039518.1|UniProtKB=A0A5F8H4K4 A0A5F8H4K4 PTHR46118:SF4 PROTEIN ABHD11 SN-1-SPECIFIC DIACYLGLYCEROL LIPASE ABHD11 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000003664.4|UniProtKB=F7ACC0 F7ACC0 HPS1 PTHR12761:SF1 HERMANSKY-PUDLAK SYNDROME PROTEIN 1 BLOC-3 COMPLEX MEMBER HPS1 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cellular pigmentation#GO:0033059;organelle assembly#GO:0070925;melanosome organization#GO:0032438;pigmentation#GO:0043473;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 MONDO|Ensembl=ENSMODG00000016045.3|UniProtKB=F6YUI8 F6YUI8 UBD PTHR47731:SF1 UBIQUITIN D UBIQUITIN D binding#GO:0005488;protein-containing complex binding#GO:0044877 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent protein catabolic process#GO:0019941;positive regulation of signal transduction#GO:0009967;protein modification process#GO:0036211;primary metabolic process#GO:0044238;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;defense response#GO:0006952;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;innate immune response#GO:0045087;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;response to tumor necrosis factor#GO:0034612;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to other organism#GO:0051707;post-translational protein modification#GO:0043687;positive regulation of response to stimulus#GO:0048584;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein modification by small protein conjugation or removal#GO:0070647;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of programmed cell death#GO:0043067;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of apoptotic process#GO:0043065;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;response to type II interferon#GO:0034341;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;protein ubiquitination#GO:0016567;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000017693.4|UniProtKB=F7G5B1 F7G5B1 SPG11 PTHR13650:SF2 SPATACSIN SPATACSIN plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;vesicle localization#GO:0051648;axon development#GO:0061564;axo-dendritic transport#GO:0008088;neurogenesis#GO:0022008;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;transport#GO:0006810;developmental process#GO:0032502;intracellular transport#GO:0046907;microtubule-based movement#GO:0007018;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;organelle localization#GO:0051640;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;synaptic vesicle transport#GO:0048489;neuron projection development#GO:0031175;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell development#GO:0048468;signaling#GO:0023052;establishment of organelle localization#GO:0051656;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;neuron projection#GO:0043005 MONDO|Ensembl=ENSMODG00000047301.1|UniProtKB=A0A5F8G4V3 A0A5F8G4V3 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000012050.4|UniProtKB=F7ALE8 F7ALE8 CTNNA1 PTHR18914:SF24 ALPHA CATENIN CATENIN ALPHA-1 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;beta-catenin binding#GO:0008013;protein-containing complex binding#GO:0044877 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cell migration#GO:0016477;cell motility#GO:0048870 extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;anchoring junction#GO:0070161;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 Wnt signaling pathway#P00057>alpha-catenin#P01471;Alzheimer disease-presenilin pathway#P00004>alpha-catenin#P00133;Cadherin signaling pathway#P00012>alpha-catenin#P00467 MONDO|Ensembl=ENSMODG00000040275.1|UniProtKB=A0A5F8GWT9 A0A5F8GWT9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000015756.3|UniProtKB=F7AH04 F7AH04 MVP PTHR14165:SF3 MAJOR VAULT PROTEIN MAJOR VAULT PROTEIN cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000023993.2|UniProtKB=F7DPU3 F7DPU3 PTHR26450:SF177 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52I1-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023976.2|UniProtKB=F7E946 F7E946 OR51S1 PTHR26450:SF73 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51S1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000034256.2|UniProtKB=A0A5F8H550 A0A5F8H550 PTHR22639:SF12 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3-LIKE viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016735.4|UniProtKB=F7BYS6 F7BYS6 GATA3 PTHR10071:SF106 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANS-ACTING T-CELL-SPECIFIC TRANSCRIPTION FACTOR GATA-3 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;immune system development#GO:0002520;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;positive regulation of macromolecule metabolic process#GO:0010604;embryo development#GO:0009790;regulation of multicellular organismal process#GO:0051239;regulation of epithelial cell differentiation#GO:0030856;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;embryonic organ development#GO:0048568;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000047160.1|UniProtKB=A0A5F8GSR7 A0A5F8GSR7 PTHR24390:SF290 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 184 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000020761.4|UniProtKB=F6ZYV0 F6ZYV0 C4orf33 PTHR31475:SF3 UPF0462 PROTEIN UPF0462 PROTEIN C4ORF33 MONDO|Ensembl=ENSMODG00000011110.4|UniProtKB=F7EPS5 F7EPS5 PTHR23045:SF9 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A-RELATED transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009554.3|UniProtKB=F7BJX9 F7BJX9 MYOZ3 PTHR15941:SF15 MYOZENIN MYOZENIN-3 molecular condensate scaffold activity#GO:0140693;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;cellular response to stimulus#GO:0051716;muscle cell development#GO:0055001;system process#GO:0003008;cellular developmental process#GO:0048869;developmental process#GO:0032502;tissue development#GO:0009888;multicellular organismal process#GO:0032501;skeletal muscle tissue development#GO:0007519;striated muscle cell development#GO:0055002;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;striated muscle tissue development#GO:0014706;cellular anatomical entity morphogenesis#GO:0032989;muscle organ development#GO:0007517;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 I band#GO:0031674;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;sarcomere#GO:0030017;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000010531.4|UniProtKB=F7D633 F7D633 PTHR24343:SF301 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 5 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000014818.3|UniProtKB=F7D2B4 F7D2B4 DGKE PTHR11255:SF54 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE EPSILON phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;membrane#GO:0016020 kinase#PC00137;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000023331.3|UniProtKB=F7CCV4 F7CCV4 PTHR46542:SF1 X-BOX BINDING PROTEIN 1 X-BOX-BINDING PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000006324.3|UniProtKB=F7AGW7 F7AGW7 PHAF1 PTHR13465:SF5 UPF0183 PROTEIN PHAGOSOME ASSEMBLY FACTOR 1 protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;Golgi to plasma membrane protein transport#GO:0043001;Golgi to plasma membrane transport#GO:0006893;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;protein localization to cell periphery#GO:1990778;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036 intracellular vesicle#GO:0097708;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;organelle subcompartment#GO:0031984;presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;dendritic tree#GO:0097447;dendrite#GO:0030425;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;somatodendritic compartment#GO:0036477;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000013248.5|UniProtKB=F7DUM8 F7DUM8 TRA2B PTHR48034:SF1 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED TRANSFORMER-2 PROTEIN HOMOLOG BETA mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000019723.5|UniProtKB=F6XLS8 F6XLS8 JMY PTHR23330:SF8 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED JUNCTION-MEDIATING AND -REGULATORY PROTEIN transcription coregulator activity#GO:0003712;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713;protein-containing complex binding#GO:0044877 cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;regulation of apoptotic process#GO:0042981;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;intrinsic apoptotic signaling pathway#GO:0097193;signal transduction by p53 class mediator#GO:0072331;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;Arp2/3 complex-mediated actin nucleation#GO:0034314;apoptotic signaling pathway#GO:0097190;actin filament organization#GO:0007015;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;intracellular signal transduction#GO:0035556;actin filament-based process#GO:0030029 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000007171.4|UniProtKB=F6RCB4 F6RCB4 PARP2 PTHR10459:SF118 DNA LIGASE POLY [ADP-RIBOSE] POLYMERASE 2 pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 MONDO|Ensembl=ENSMODG00000024654.2|UniProtKB=F6XB70 F6XB70 ACTL7A PTHR11937:SF167 ACTIN ACTIN-LIKE PROTEIN 7A structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000025264.3|UniProtKB=F7ARR8 F7ARR8 HFM1 PTHR47835:SF3 HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG ATP-DEPENDENT DNA HELICASE HFM1-RELATED MONDO|Ensembl=ENSMODG00000041106.1|UniProtKB=A0A5F8H3F3 A0A5F8H3F3 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014491.2|UniProtKB=F7FKT3 F7FKT3 RNASEH1 PTHR10642:SF35 RIBONUCLEASE H1 RIBONUCLEASE H1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;catabolic process#GO:0009056;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;DNA-templated DNA replication#GO:0006261;mitochondrial DNA metabolic process#GO:0032042;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;endoribonuclease#PC00094 DNA replication#P00017>RNase H#P00538 MONDO|Ensembl=ENSMODG00000021000.4|UniProtKB=F6RJW6 F6RJW6 ADAMTS1 PTHR13723:SF40 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000013699.4|UniProtKB=A0A5F8H274 A0A5F8H274 PTHR16517:SF24 TUBBY-RELATED TUBBY-RELATED PROTEIN 2 protein localization to cilium#GO:0061512;intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365;macromolecule localization#GO:0033036 plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000021249.4|UniProtKB=F6TIV9 F6TIV9 PLSCR5 PTHR23248:SF25 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE FAMILY MEMBER 5 intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128 lipid localization#GO:0010876;localization#GO:0051179;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;endomembrane system organization#GO:0010256;phospholipid translocation#GO:0045332 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000014518.3|UniProtKB=F7ERQ8 F7ERQ8 AARS PTHR11777:SF36 ALANYL-TRNA SYNTHETASE ALANINE--TRNA LIGASE, CYTOPLASMIC hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;carboxylic ester hydrolase activity#GO:0052689;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;deacylase activity#GO:0160215;catalytic activity#GO:0003824;ligase activity#GO:0016874;hydrolase activity, acting on ester bonds#GO:0016788 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000016901.3|UniProtKB=F6X1A4 F6X1A4 SMG5 PTHR15696:SF7 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 NONSENSE-MEDIATED MRNA DECAY FACTOR telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000010141.4|UniProtKB=F6W884 F6W884 FAM199X PTHR32003:SF1 PROTEIN FAM199X PROTEIN FAM199X MONDO|Ensembl=ENSMODG00000001635.4|UniProtKB=F6TN87 F6TN87 PTHR12845:SF2 GUANINE NUCLEOTIDE EXCHANGE FACTOR DH DOMAIN-CONTAINING PROTEIN-RELATED guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament-based process#GO:0032970 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000028880.2|UniProtKB=F7AIC9 F7AIC9 SPMIP10 PTHR35247:SF1 TESTIS-EXPRESSED PROTEIN 43 TESTIS EXPRESSED 43 MONDO|Ensembl=ENSMODG00000003539.2|UniProtKB=F7GBQ2 F7GBQ2 FITM1 PTHR23129:SF3 ACYL-COENZYME A DIPHOSPHATASE FITM2 FAT STORAGE-INDUCING TRANSMEMBRANE PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 organelle assembly#GO:0070925;lipid droplet organization#GO:0034389;homeostatic process#GO:0042592;cell differentiation#GO:0030154;fat cell differentiation#GO:0045444;membraneless organelle assembly#GO:0140694;lipid homeostasis#GO:0055088;cellular component organization#GO:0016043;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;chemical homeostasis#GO:0048878;developmental process#GO:0032502;cellular component assembly#GO:0022607;cellular process#GO:0009987;lipid storage#GO:0019915;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000000018.4|UniProtKB=F6SIE6 F6SIE6 SUN5 PTHR12911:SF44 SAD1/UNC-84-LIKE PROTEIN-RELATED SUN DOMAIN-CONTAINING PROTEIN 5 protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 membrane#GO:0016020;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000018706.4|UniProtKB=F7FCL0 F7FCL0 PTHR43407:SF1 GLUTAMINE SYNTHETASE LENGSIN catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;homeostatic process#GO:0042592;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;response to nutrient levels#GO:0031667;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039 membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ligase#PC00142 Glutamine glutamate conversion#P02745>Glutamine synthase#P04483 MONDO|Ensembl=ENSMODG00000004632.5|UniProtKB=A0A5F8H6Q2 A0A5F8H6Q2 COL4A2 PTHR24023:SF588 COLLAGEN ALPHA COLLAGEN ALPHA-2(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;extracellular structure organization#GO:0043062;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;extracellular matrix organization#GO:0030198;cell communication#GO:0007154;external encapsulating structure organization#GO:0045229;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840 extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000010369.4|UniProtKB=F6R3Z0 F6R3Z0 ITGA4 PTHR23220:SF78 INTEGRIN ALPHA INTEGRIN ALPHA-4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell surface receptor signaling pathway#GO:0007166;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155 integrin complex#GO:0008305;signaling receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 cell adhesion molecule#PC00069;integrin#PC00126 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853;Integrin signalling pathway#P00034>Integrin alpha#P00941 MONDO|Ensembl=ENSMODG00000015635.3|UniProtKB=F7FEK6 F7FEK6 PTHR10658:SF85 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PHOSPHATIDYLINOSITOL TRANSFER PROTEIN N-TERMINAL DOMAIN-CONTAINING PROTEIN anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylcholine intramembrane carrier activity#GO:0008525;lipid carrier activity#GO:0005319;intramembrane lipid carrier activity#GO:0140303;cation binding#GO:0043169;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylcholine binding#GO:0031210;phosphatidylinositol transfer activity#GO:0008526;binding#GO:0005488;molecular carrier activity#GO:0140104;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;transporter activity#GO:0005215 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000045617.1|UniProtKB=A0A5F8H4R1 A0A5F8H4R1 GPX8 PTHR11592:SF7 GLUTATHIONE PEROXIDASE PROTEIN PEROXIDASE GPX8 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824 response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979 peroxidase#PC00180;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000002961.3|UniProtKB=F6Q5D8 F6Q5D8 GCGR PTHR45620:SF29 PDF RECEPTOR-LIKE PROTEIN-RELATED GLUCAGON RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045190.1|UniProtKB=F7C468 F7C468 LOC103093916 PTHR26453:SF76 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13H1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012591.4|UniProtKB=F6PIJ7 F6PIJ7 DNAH10 PTHR10676:SF343 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 10 catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;microtubule motor activity#GO:0003777 cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;microtubule-based process#GO:0007017;cilium-dependent cell motility#GO:0060285;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;cell motility#GO:0048870;microtubule-based movement#GO:0007018 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;dynein complex#GO:0030286;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cilium#GO:0005929;catalytic complex#GO:1902494;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000004782.4|UniProtKB=A0A5F8GPP8 A0A5F8GPP8 TMPRSS9 PTHR24253:SF81 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 9 serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;zymogen activation#GO:0031638;primary metabolic process#GO:0044238;plasminogen activation#GO:0031639;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000018976.4|UniProtKB=F7FP84 F7FP84 PRSS12 PTHR48071:SF5 SRCR DOMAIN-CONTAINING PROTEIN NEUROTRYPSIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;zymogen activation#GO:0031638;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 cell junction#GO:0030054;axon terminus#GO:0043679;membrane#GO:0016020;presynapse#GO:0098793;neuron projection#GO:0043005;cell periphery#GO:0071944;glutamatergic synapse#GO:0098978;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;extracellular region#GO:0005576;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron projection terminus#GO:0044306;cell projection#GO:0042995;terminal bouton#GO:0043195;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025 MONDO|Ensembl=ENSMODG00000024283.2|UniProtKB=F6Z4W5 F6Z4W5 LOC100012481 PTHR26453:SF284 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6B1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048987.1|UniProtKB=A0A5F8HAV8 A0A5F8HAV8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000013322.4|UniProtKB=A0A5F8H8R3 A0A5F8H8R3 ZFAND3 PTHR10634:SF67 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE ZINC FINGER PROTEIN 3 MONDO|Ensembl=ENSMODG00000051021.1|UniProtKB=A0A5F8GV08 A0A5F8GV08 FEM1B PTHR24173:SF78 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG B molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000044469.1|UniProtKB=F7BLY8 F7BLY8 LOC100618782 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000016370.3|UniProtKB=F7ERR3 F7ERR3 PTHR46879:SF1 SUSHI DOMAIN-CONTAINING PROTEIN 3 SUSHI DOMAIN-CONTAINING PROTEIN 3 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000048958.1|UniProtKB=A0A5F8GGS9 A0A5F8GGS9 RASD2 PTHR46149:SF1 MIP08469P GTP-BINDING PROTEIN RHES binding#GO:0005488;protein binding#GO:0005515 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 MONDO|Ensembl=ENSMODG00000024919.3|UniProtKB=A0A5F8GV13 A0A5F8GV13 NCKAP5 PTHR21740:SF0 NCK-ASSOCIATED PROTEIN 5 NCK-ASSOCIATED PROTEIN 5 cytoskeleton organization#GO:0007010;protein-containing complex disassembly#GO:0032984;protein depolymerization#GO:0051261;microtubule depolymerization#GO:0007019;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular component disassembly#GO:0022411;microtubule bundle formation#GO:0001578 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;microtubule plus-end#GO:0035371;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule cytoskeleton#GO:0015630;microtubule end#GO:1990752;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000041443.1|UniProtKB=F6Q111 F6Q111 LOC100023310 PTHR26450:SF89 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52B4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024242.2|UniProtKB=A0A5F8G4F2 A0A5F8G4F2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000045088.1|UniProtKB=F7BJB4 F7BJB4 LOC100028963 PTHR48002:SF17 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4N5 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038556.1|UniProtKB=A0A5F8HE78 A0A5F8HE78 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000021259.4|UniProtKB=F6T3C1 F6T3C1 HPS3 PTHR28633:SF1 HERMANSKY-PUDLAK SYNDROME 3 PROTEIN BLOC-2 COMPLEX MEMBER HPS3 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000011146.4|UniProtKB=A0A5F8H8D4 A0A5F8H8D4 LDB3 PTHR24214:SF9 PDZ AND LIM DOMAIN PROTEIN ZASP LIM DOMAIN-BINDING PROTEIN 3 protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular component organization#GO:0016043;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;system development#GO:0048731;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;heart development#GO:0007507;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 cytoskeleton#GO:0005856;stress fiber#GO:0001725;actin filament#GO:0005884;I band#GO:0031674;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054;sarcomere#GO:0030017;adherens junction#GO:0005912;cell-cell junction#GO:0005911;actomyosin#GO:0042641;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;myofibril#GO:0030016;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000040034.1|UniProtKB=A0A5F8HGL7 A0A5F8HGL7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000011125.4|UniProtKB=F7BB74 F7BB74 INA PTHR45652:SF18 GLIAL FIBRILLARY ACIDIC PROTEIN ALPHA-INTERNEXIN structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;cytoskeleton organization#GO:0007010 postsynapse#GO:0098794;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882 cytoskeletal protein#PC00085;intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000002831.3|UniProtKB=F7EIW1 F7EIW1 XPO1 PTHR11223:SF2 EXPORTIN 1/5 EXPORTIN-1 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;ribosomal large subunit export from nucleus#GO:0000055;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;ribosome localization#GO:0033750;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;organelle localization#GO:0051640;ribosome biogenesis#GO:0042254;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 MONDO|Ensembl=ENSMODG00000045381.1|UniProtKB=A0A5F8GXM8 A0A5F8GXM8 PTHR43340:SF6 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;metal ion binding#GO:0046872;magnesium ion binding#GO:0000287;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;pentosyltransferase activity#GO:0016763 nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;IMP metabolic process#GO:0046040;primary metabolic process#GO:0044238;nucleobase metabolic process#GO:0009112;nucleoside phosphate biosynthetic process#GO:1901293;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247;Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804;Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245 MONDO|Ensembl=ENSMODG00000039939.1|UniProtKB=K7E4W6 K7E4W6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000038657.1|UniProtKB=A0A5F8GXZ0 A0A5F8GXZ0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000017361.4|UniProtKB=A0A5F8GUS4 A0A5F8GUS4 PUS7 PTHR13326:SF31 TRNA PSEUDOURIDINE SYNTHASE D PSEUDOURIDYLATE SYNTHASE 7 HOMOLOG isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866 nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;pseudouridine synthesis#GO:0001522;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;metabolic process#GO:0008152;RNA modification#GO:0009451 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000029337.2|UniProtKB=A0A5F8H9I3 A0A5F8H9I3 PTHR37869:SF1 TRANSMEMBRANE PROTEIN 89 TRANSMEMBRANE PROTEIN 89 MONDO|Ensembl=ENSMODG00000008299.4|UniProtKB=F7FTW9 F7FTW9 NPAS4 PTHR23043:SF24 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA NEURONAL PAS DOMAIN-CONTAINING PROTEIN 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000016626.4|UniProtKB=A0A5F8H979 A0A5F8H979 CCT7 PTHR11353:SF22 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ETA metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031 chaperonin#PC00073 MONDO|Ensembl=ENSMODG00000004393.4|UniProtKB=F6SVQ4 F6SVQ4 IRF2 PTHR11949:SF22 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000010456.4|UniProtKB=F7F7R5 F7F7R5 DELE1 PTHR45011:SF1 DAP3-BINDING CELL DEATH ENHANCER 1 DAP3-BINDING CELL DEATH ENHANCER 1 protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;response to stress#GO:0006950;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000014981.5|UniProtKB=F7CGD3 F7CGD3 PLEKHH3 PTHR46049:SF5 AGAP003327-PA PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 3 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000018289.4|UniProtKB=A0A5F8HKX8 A0A5F8HKX8 RNGTT PTHR10367:SF17 MRNA-CAPPING ENZYME MRNA-CAPPING ENZYME catalytic activity, acting on RNA#GO:0140098;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 RNA processing factor#PC00147;mRNA capping factor#PC00145 MONDO|Ensembl=ENSMODG00000038382.1|UniProtKB=A0A5F8GG07 A0A5F8GG07 F3 PTHR20859:SF22 INTERFERON/INTERLEUKIN RECEPTOR TISSUE FACTOR immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Blood coagulation#P00011>Tissue Factor#P00450;Angiogenesis#P00005>TF#P00191 MONDO|Ensembl=ENSMODG00000017520.3|UniProtKB=F7EIJ4 F7EIJ4 RPS12 PTHR11843:SF0 40S RIBOSOMAL PROTEIN S12 SMALL RIBOSOMAL SUBUNIT PROTEIN ES12 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;translation#GO:0006412;ribosomal small subunit biogenesis#GO:0042274;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component biogenesis#GO:0044085 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000024127.3|UniProtKB=A0A5F8H4F2 A0A5F8H4F2 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019244.4|UniProtKB=F6QTH2 F6QTH2 VTN PTHR22917:SF3 HEMOPEXIN DOMAIN-CONTAINING PROTEIN VITRONECTIN integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;extracellular matrix binding#GO:0050840;cell adhesion molecule binding#GO:0050839;signaling receptor binding#GO:0005102;binding#GO:0005488 cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;cell adhesion mediated by integrin#GO:0033627;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000008041.4|UniProtKB=A0A5F8HA99 A0A5F8HA99 PTHR10579:SF42 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CHLORIDE CHANNEL ACCESSORY 3B monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;chloride channel activity#GO:0005254;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000046264.1|UniProtKB=A0A5F8GQS4 A0A5F8GQS4 CMKLR2 PTHR24229:SF4 NEUROPEPTIDES RECEPTOR CHEMERIN-LIKE RECEPTOR 2 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;neuropeptide binding#GO:0042923;peptide binding#GO:0042277 neuropeptide signaling pathway#GO:0007218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000022587.3|UniProtKB=H9H860 H9H860 CCT8L2 PTHR11353:SF100 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT THETA-LIKE 1-RELATED gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 chaperonin#PC00073 MONDO|Ensembl=ENSMODG00000002434.4|UniProtKB=F7DZW2 F7DZW2 SLC9A2 PTHR10110:SF89 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 2 antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;import into cell#GO:0098657;establishment of localization#GO:0051234;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000024555.1|UniProtKB=F7F1U2 F7F1U2 GPR85 PTHR19268:SF7 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 85-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018518.4|UniProtKB=F7AG95 F7AG95 EPHB1 PTHR24416:SF603 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-B RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 Angiogenesis#P00005>EphR#P00212 MONDO|Ensembl=ENSMODG00000051440.1|UniProtKB=K7E362 K7E362 LOC107652043 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED RETROVIRAL ENVELOPE PROTEIN GP41-LIKE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000040098.1|UniProtKB=A0A5F8GGA9 A0A5F8GGA9 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009337.4|UniProtKB=F7GAY1 F7GAY1 SCRN3 PTHR12994:SF18 SECERNIN SECERNIN-3 MONDO|Ensembl=ENSMODG00000021218.4|UniProtKB=F6UG25 F6UG25 DAW1 PTHR44156:SF33 SUPERNUMERARY LIMBS, ISOFORM B-RELATED DYNEIN ASSEMBLY FACTOR WITH WD REPEAT DOMAINS 1 pattern specification process#GO:0007389;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;cilium organization#GO:0044782;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;determination of left/right symmetry#GO:0007368;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;left/right pattern formation#GO:0060972;developmental process#GO:0032502;specification of symmetry#GO:0009799;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;determination of bilateral symmetry#GO:0009855;cellular component assembly#GO:0022607;regionalization#GO:0003002;multicellular organismal process#GO:0032501 MONDO|Ensembl=ENSMODG00000011873.4|UniProtKB=F7G715 F7G715 MRPL3 PTHR11229:SF8 50S RIBOSOMAL PROTEIN L3 LARGE RIBOSOMAL SUBUNIT PROTEIN UL3M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000016006.4|UniProtKB=F7EGD2 F7EGD2 PTHR11596:SF74 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 ossification#GO:0001503;tissue development#GO:0009888;multicellular organismal process#GO:0032501;animal organ development#GO:0048513;anatomical structure development#GO:0048856;bone mineralization#GO:0030282;animal gross anatomical part developmental process#GO:0160108;biomineral tissue development#GO:0031214;developmental process#GO:0032502 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000019538.4|UniProtKB=F6UUJ2 F6UUJ2 PTHR20937:SF6 IP14615P MESODERM POSTERIOR PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 mesoderm morphogenesis#GO:0048332;heart morphogenesis#GO:0003007;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;embryo development ending in birth or egg hatching#GO:0009792;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;mesoderm formation#GO:0001707;epithelium development#GO:0060429;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;gastrulation#GO:0007369;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;formation of primary germ layer#GO:0001704;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;embryonic pattern specification#GO:0009880;embryo development#GO:0009790;heart development#GO:0007507;anterior/posterior pattern specification#GO:0009952;anatomical structure formation involved in morphogenesis#GO:0048646;animal organ development#GO:0048513;anterior/posterior axis specification#GO:0009948;mesoderm development#GO:0007498;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000002796.4|UniProtKB=F7EJL2 F7EJL2 VAV3 PTHR45818:SF1 PROTEIN VAV GUANINE NUCLEOTIDE EXCHANGE FACTOR VAV3 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 intracellular signal transduction#GO:0035556;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of cell communication#GO:0010646;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;cell migration#GO:0016477;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;cell surface receptor signaling pathway#GO:0007166;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 T cell activation#P00053>vav#P01295;PDGF signaling pathway#P00047>Vav#P01169;B cell activation#P00010>vav#P00368 MONDO|Ensembl=ENSMODG00000016663.4|UniProtKB=F7G6Y7 F7G6Y7 PRKCQ PTHR24356:SF181 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C THETA TYPE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Apoptosis signaling pathway#P00006>PKCs#P00318;FGF signaling pathway#P00021>PKC#P00648;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Wnt signaling pathway#P00057>Protein Kinase C#P01458;CCKR signaling map#P06959>PKCtheta#P07140;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;T cell activation#P00053>PKC-theta#P01318;Endothelin signaling pathway#P00019>PKC#P00568;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565;Gonadotropin-releasing hormone receptor pathway#P06664>PKCe/theta#P06798;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219 MONDO|Ensembl=ENSMODG00000019067.4|UniProtKB=F7FZ94 F7FZ94 SGCZ PTHR12939:SF5 SARCOGLYCAN ZETA-SARCOGLYCAN circulatory system development#GO:0072359;heart process#GO:0003015;anatomical structure development#GO:0048856;system development#GO:0048731;muscle tissue development#GO:0060537;circulatory system process#GO:0003013;animal gross anatomical part developmental process#GO:0160108;blood circulation#GO:0008015;heart development#GO:0007507;tissue development#GO:0009888;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;animal organ development#GO:0048513;system process#GO:0003008;heart contraction#GO:0060047;developmental process#GO:0032502;striated muscle tissue development#GO:0014706 sarcolemma#GO:0042383;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000003157.1|UniProtKB=F6WE13 F6WE13 TRIAP1 PTHR46403:SF3 TP53-REGULATED INHIBITOR OF APOPTOSIS 1 TP53-REGULATED INHIBITOR OF APOPTOSIS 1 lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 localization#GO:0051179;lipid localization#GO:0010876;regulation of cellular process#GO:0050794;organophosphate ester transport#GO:0015748;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of apoptotic process#GO:0042981;transport#GO:0006810;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;phospholipid transport#GO:0015914;intermembrane phospholipid transfer#GO:0120010;membrane organization#GO:0061024;lipid transport#GO:0006869;negative regulation of apoptotic process#GO:0043066;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;macromolecule localization#GO:0033036 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000019214.4|UniProtKB=F6ZHY7 F6ZHY7 NAAA PTHR28583:SF4 ACID AMIDASE N-ACYLETHANOLAMINE-HYDROLYZING ACID AMIDASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000007955.4|UniProtKB=F7EA03 F7EA03 KBTBD12 PTHR24412:SF510 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 12 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010762.4|UniProtKB=F7FK78 F7FK78 DTNBP1 PTHR16294:SF5 DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN DYSBINDIN neuron development#GO:0048666;cellular localization#GO:0051641;regulation of signaling#GO:0023051;microtubule-based transport#GO:0099111;animal gross anatomical part developmental process#GO:0160108;regulation of neurotransmitter transport#GO:0051588;regulation of synaptic vesicle exocytosis#GO:2000300;cell development#GO:0048468;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;organelle transport along microtubule#GO:0072384;nervous system development#GO:0007399;endomembrane system organization#GO:0010256;regulation of trans-synaptic signaling#GO:0099177;synaptic vesicle localization#GO:0097479;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle transport#GO:0048489;organelle organization#GO:0006996;neuron projection development#GO:0031175;regulation of exocytosis#GO:0017157;anatomical structure development#GO:0048856;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;neurogenesis#GO:0022008;vesicle cytoskeletal trafficking#GO:0099518;transport#GO:0006810;regulation of response to stimulus#GO:0048583;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;regulation of secretion by cell#GO:1903530;generation of neurons#GO:0048699;regulation of neurotransmitter secretion#GO:0046928;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cellular component organization#GO:0016043;vesicle organization#GO:0016050;microtubule-based process#GO:0007017;regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of vesicle localization#GO:0051650;anterograde axonal transport#GO:0008089;system development#GO:0048731;localization#GO:0051179;regulation of secretion#GO:0051046;organelle localization#GO:0051640;axonal transport#GO:0098930;anterograde synaptic vesicle transport#GO:0048490;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;regulation of signal transduction#GO:0009966;vesicle localization#GO:0051648;axo-dendritic transport#GO:0008088 bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular vesicle#GO:0097708;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;BLOC-1 complex#GO:0031083;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000014517.4|UniProtKB=F7ERS0 F7ERS0 SNX6 PTHR45850:SF4 SORTING NEXIN FAMILY MEMBER SORTING NEXIN-6 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014252.3|UniProtKB=F6Y1F9 F6Y1F9 FAM110C PTHR14758:SF5 AGAP005440-PA PROTEIN FAM110C cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;protein binding#GO:0005515 positive regulation of cell motility#GO:2000147;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of cell migration#GO:0030335;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cellular component biogenesis#GO:0044087;regulation of cell projection organization#GO:0031344;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017;regulation of cell projection assembly#GO:0060491 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938 MONDO|Ensembl=ENSMODG00000028335.2|UniProtKB=A0A5F8GK75 A0A5F8GK75 PTHR47901:SF6 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18 CASPASE 4 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;protein metabolic process#GO:0019538;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;proteolysis#GO:0006508;biosynthetic process#GO:0009058;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of response to external stimulus#GO:0032101;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;macromolecule metabolic process#GO:0043170;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;metabolic process#GO:0008152 canonical inflammasome complex#GO:0061702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000049924.1|UniProtKB=A0A5F8HLH1 A0A5F8HLH1 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000036638.1|UniProtKB=A0A5F8H3Y5 A0A5F8H3Y5 PTHR24203:SF84 ANKYRIN REPEAT FAMILY PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 6 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;establishment or maintenance of cell polarity#GO:0007163;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987 Wnt signaling pathway#P00057>Diversin#P01466 MONDO|Ensembl=ENSMODG00000029379.2|UniProtKB=K7E3L0 K7E3L0 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000010066.3|UniProtKB=F6Y536 F6Y536 ESS2 PTHR12940:SF0 ES-2 PROTEIN - RELATED SPLICING FACTOR ESS-2 HOMOLOG protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000004449.4|UniProtKB=F6RS33 F6RS33 UPP2 PTHR43691:SF8 URIDINE PHOSPHORYLASE URIDINE PHOSPHORYLASE 2 glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;nucleoside catabolic process#GO:0009164;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;nucleobase-containing small molecule catabolic process#GO:0034656;primary metabolic process#GO:0044238 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine phosphorylase#P03152 MONDO|Ensembl=ENSMODG00000044059.1|UniProtKB=A0A5F8GMM8 A0A5F8GMM8 PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987 reductase#PC00198 MONDO|Ensembl=ENSMODG00000038878.1|UniProtKB=A0A5F8GH56 A0A5F8GH56 PTHR14735:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 134 COILED-COIL DOMAIN-CONTAINING PROTEIN 134 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000021018.4|UniProtKB=F6QZC5 F6QZC5 TFF2 PTHR13826:SF17 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 2 system process#GO:0003008;tissue homeostasis#GO:0001894;multicellular organismal-level homeostasis#GO:0048871;digestion#GO:0007586;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;homeostatic process#GO:0042592;epithelial structure maintenance#GO:0010669 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CCKR signaling map#P06959>TFF2#G07264;CCKR signaling map#P06959>TFF2#G06971 MONDO|Ensembl=ENSMODG00000005183.5|UniProtKB=F7DNJ6 F7DNJ6 ESRP2 PTHR13976:SF30 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED EPITHELIAL SPLICING REGULATORY PROTEIN 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000023924.4|UniProtKB=F7BD28 F7BD28 TWIST1 PTHR23349:SF64 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TWIST-RELATED PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000050971.1|UniProtKB=O62739 O62739 RPS4Y1 PTHR11581:SF0 30S/40S RIBOSOMAL PROTEIN S4 RIBOSOMAL PROTEIN S4 Y1-RELATED structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000048836.1|UniProtKB=A0A5F8HGU3 A0A5F8HGU3 PTHR13156:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;respiratory chain complex I#GO:0045271;organelle membrane#GO:0031090;transporter complex#GO:1990351 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000024655.3|UniProtKB=F6XB36 F6XB36 TPMT PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity#GO:0003824;transferase activity#GO:0016740 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000009729.4|UniProtKB=F6XAK8 F6XAK8 ST8SIA6 PTHR11987:SF29 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-2,8-SIALYLTRANSFERASE 8F sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;oligosaccharide metabolic process#GO:0009311;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000041415.1|UniProtKB=A0A5F8HDS5 A0A5F8HDS5 LBH PTHR14987:SF2 PROTEIN LBH-RELATED PROTEIN LBH positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000006873.4|UniProtKB=F6PWI8 F6PWI8 DYNC1LI2 PTHR12688:SF1 DYNEIN LIGHT INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 LIGHT INTERMEDIATE CHAIN 2 protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoplasmic dynein complex#GO:0005868;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;dynein complex#GO:0030286;kinetochore#GO:0000776;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000038120.1|UniProtKB=A0A5F8G6J7 A0A5F8G6J7 INKA2 PTHR28615:SF2 PAK4-INHIBITOR INKA1-RELATED PAK4-INHIBITOR INKA2 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme inhibitor activity#GO:0004857;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;kinase inhibitor activity#GO:0019210 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000005999.3|UniProtKB=F6SKY7 F6SKY7 CERCAM PTHR10730:SF9 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER INACTIVE GLYCOSYLTRANSFERASE 25 FAMILY MEMBER 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000009316.4|UniProtKB=A0A5F8HG80 A0A5F8HG80 EIF3A PTHR14005:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3, THETA SUBUNIT EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467 cytosol#GO:0005829;eukaryotic translation initiation factor 3 complex#GO:0005852;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000004233.4|UniProtKB=F6UBN5 F6UBN5 PTHR10962:SF7 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2A peptide binding#GO:0042277;binding#GO:0005488 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000011738.3|UniProtKB=A0A5F8GXH1 A0A5F8GXH1 GKN2 PTHR16483:SF3 GASTROKINE 1 GASTROKINE-2 biological regulation#GO:0065007;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000010974.2|UniProtKB=F7AQB9 F7AQB9 GPT PTHR11751:SF308 ALANINE AMINOTRANSFERASE ALANINE AMINOTRANSFERASE 1 transferase#PC00220;transaminase#PC00216 MONDO|Ensembl=ENSMODG00000015348.4|UniProtKB=A0A5F8G2F4 A0A5F8G2F4 PTHR46127:SF2 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 65 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 65 plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;developmental process#GO:0032502;spermatogenesis#GO:0007283;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;organelle assembly#GO:0070925;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;microtubule-based process#GO:0007017;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;9+2 motile cilium#GO:0097729;cilium#GO:0005929;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000016982.4|UniProtKB=F6UL60 F6UL60 PROS1 PTHR24040:SF0 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN VITAMIN K-DEPENDENT PROTEIN S negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of coagulation#GO:0050819;regulation of coagulation#GO:0050818;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 Blood coagulation#P00011>PS#P00412 MONDO|Ensembl=ENSMODG00000017143.4|UniProtKB=A0A5F8GEF7 A0A5F8GEF7 MAGI2 PTHR10316:SF27 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 2 signaling adaptor activity#GO:0035591;signaling receptor complex adaptor activity#GO:0030159;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;protein localization to membrane#GO:0072657;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular localization#GO:0051641;localization#GO:0051179;cell communication#GO:0007154;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;receptor clustering#GO:0043113;localization within membrane#GO:0051668;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cellular process#GO:0009987;regulation of protein localization to membrane#GO:1905475;signal transduction#GO:0007165;regulation of localization#GO:0032879;intracellular protein localization#GO:0008104 cell junction#GO:0030054;adherens junction#GO:0005912;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;dendrite#GO:0030425;dendritic tree#GO:0097447;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell-cell junction#GO:0005911;neuron projection#GO:0043005 MONDO|Ensembl=ENSMODG00000010488.3|UniProtKB=F7ES92 F7ES92 TLCD2 PTHR13439:SF2 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 2 plasma membrane organization#GO:0007009;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;regulation of biological quality#GO:0065008;chemical homeostasis#GO:0048878;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;homeostatic process#GO:0042592;biological regulation#GO:0065007;membrane organization#GO:0061024;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;lipid homeostasis#GO:0055088;membrane assembly#GO:0071709;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000016243.5|UniProtKB=F7C2H5 F7C2H5 NCOA3 PTHR10684:SF3 NUCLEAR RECEPTOR COACTIVATOR NUCLEAR RECEPTOR COACTIVATOR 3 binding#GO:0005488;transcription regulator activity#GO:0140110;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to hormone stimulus#GO:0032870;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 Gonadotropin-releasing hormone receptor pathway#P06664>Ncoa3#P06719 MONDO|Ensembl=ENSMODG00000023915.1|UniProtKB=F7FY67 F7FY67 DIRAS1 PTHR24070:SF213 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN DI-RAS1 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000002930.4|UniProtKB=F6PMA2 F6PMA2 FRMPD1 PTHR46221:SF2 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 1 cell periphery#GO:0071944;cell cortex#GO:0005938;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000041529.1|UniProtKB=A0A5F8HKA5 A0A5F8HKA5 monDomV1R1253 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019091.3|UniProtKB=F7FNA8 F7FNA8 RABGGTB PTHR11774:SF11 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA transferase activity#GO:0016740;catalytic activity#GO:0003824;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a protein#GO:0140096 cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting#GO:0006605;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 acyltransferase#PC00042;transferase#PC00220 MONDO|Ensembl=ENSMODG00000006884.4|UniProtKB=F6PVS9 F6PVS9 HMG20B PTHR46040:SF2 HIGH MOBILITY GROUP PROTEIN 2 SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1-RELATED biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000029406.2|UniProtKB=A0A5F8GH62 A0A5F8GH62 POP4 PTHR13348:SF0 RIBONUCLEASE P SUBUNIT P29 RIBONUCLEASE P PROTEIN SUBUNIT P29 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 ribonuclease MRP complex#GO:0000172;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;catalytic complex#GO:1902494;ribonuclease P complex#GO:0030677;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;ribonucleoprotein complex#GO:1990904 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000049273.1|UniProtKB=A0A5F8HKM7 A0A5F8HKM7 LOC100011344 PTHR23430:SF381 HISTONE H2A HISTONE H2A structural molecule activity#GO:0005198 negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000005201.4|UniProtKB=F7A236 F7A236 PTHR45870:SF1 TUBULIN MONOGLYCYLASE TTLL3 TUBULIN MONOGLYCYLASE TTLL3 catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096;ligase activity, forming carbon-nitrogen bonds#GO:0016879 cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;gamete generation#GO:0007276;cell projection organization#GO:0030030;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;developmental process#GO:0032502;spermatogenesis#GO:0007283;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;sperm flagellum#GO:0036126;ciliary plasm#GO:0097014;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000018893.4|UniProtKB=A0A5F8G6X2 A0A5F8G6X2 SNX27 PTHR12431:SF19 SORTING NEXIN 17 AND 27 SORTING NEXIN-27 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 transport#GO:0006810;localization within membrane#GO:0051668;intracellular transport#GO:0046907;metabolic process#GO:0008152;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000127.4|UniProtKB=F6YBL9 F6YBL9 SHOX PTHR46255:SF2 SHORT STATURE HOMEOBOX SHORT STATURE HOMEOBOX PROTEIN double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000009888.3|UniProtKB=F6VCX0 F6VCX0 LPL PTHR11610:SF3 LIPASE LIPOPROTEIN LIPASE hydrolase activity#GO:0016787;protein binding#GO:0005515;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;binding#GO:0005488 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biological regulation#GO:0065007;catabolic process#GO:0009056;multicellular organismal process#GO:0032501;lipid catabolic process#GO:0016042;regulation of biological process#GO:0050789;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 2-arachidonoylglycerol biosynthesis#P05726>DGL#P05736 MONDO|Ensembl=ENSMODG00000023944.2|UniProtKB=F7FJZ3 F7FJZ3 PTHR13531:SF5 GEO07735P1-RELATED-RELATED TRANSMEMBRANE PROTEIN 216 cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840 cilium#GO:0005929;ciliary transition zone#GO:0035869;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000000619.4|UniProtKB=F6TAS0 F6TAS0 EIF2AK4 PTHR11042:SF202 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EIF-2-ALPHA KINASE GCN2 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554;negative regulation of translation#GO:0017148;regulation of translational initiation#GO:0006446;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;cellular response to nutrient levels#GO:0031669;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to nutrient levels#GO:0031667;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;negative regulation of protein metabolic process#GO:0051248;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000010655.4|UniProtKB=F7D442 F7D442 AHDC1 PTHR15617:SF1 TRANSCRIPTION FACTOR GIBBIN TRANSCRIPTION FACTOR GIBBIN MONDO|Ensembl=ENSMODG00000015383.4|UniProtKB=A0A5F8GAA1 A0A5F8GAA1 ASB15 PTHR24178:SF21 MOLTING PROTEIN MLT-4 ANKYRIN REPEAT AND SOCS BOX PROTEIN 3 protein localization to cilium#GO:0061512;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179;macromolecule localization#GO:0033036 cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995 MONDO|Ensembl=ENSMODG00000000187.4|UniProtKB=F6TFY1 F6TFY1 SYT4 PTHR10024:SF114 SYNAPTOTAGMIN SYNAPTOTAGMIN-4 phospholipid binding#GO:0005543;binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515;molecular sensor activity#GO:0140299;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772 secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;positive regulation of cellular component organization#GO:0051130;signaling#GO:0023052;export from cell#GO:0140352;regulation of cellular component organization#GO:0051128;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;exocytosis#GO:0006887;regulation of localization#GO:0032879;positive regulation of vesicle fusion#GO:0031340;regulation of transport#GO:0051049;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;regulated exocytosis#GO:0045055;neurotransmitter transport#GO:0006836;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;synaptic vesicle exocytosis#GO:0016079;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;synaptic signaling#GO:0099536;regulation of exocytosis#GO:0017157;localization#GO:0051179;cell communication#GO:0007154;regulation of secretion#GO:0051046;secretion#GO:0046903;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;vesicle fusion#GO:0006906;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;membrane organization#GO:0061024;neurotransmitter secretion#GO:0007269;positive regulation of cellular process#GO:0048522;membrane fusion#GO:0061025 cell junction#GO:0030054;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;axon#GO:0030424;exocytic vesicle#GO:0070382;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane trafficking regulatory protein#PC00151 Gonadotropin-releasing hormone receptor pathway#P06664>Syt IV#P06746 MONDO|Ensembl=ENSMODG00000001500.6|UniProtKB=F7F4L6 F7F4L6 LYAR PTHR13100:SF10 CELL GROWTH-REGULATING NUCLEOLAR PROTEIN LYAR CELL GROWTH-REGULATING NUCLEOLAR PROTEIN DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;rRNA processing#GO:0006364;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of metabolic process#GO:0009892 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000018187.3|UniProtKB=A0A5F8HGT1 A0A5F8HGT1 PEX5 PTHR10130:SF2 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR signal sequence receptor activity#GO:0005048;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;organelle organization#GO:0006996;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;protein import into peroxisome matrix#GO:0016558;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031;peroxisomal transport#GO:0043574;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179 membrane#GO:0016020;peroxisome#GO:0005777;cytosol#GO:0005829;microbody#GO:0042579;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000001503.2|UniProtKB=A0A5F8GPN7 A0A5F8GPN7 PTHR10741:SF2 TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X TRANSLIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000005282.1|UniProtKB=F7E6W2 F7E6W2 UFC1 PTHR12921:SF0 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;cellular response to stress#GO:0033554;process utilizing autophagic mechanism#GO:0061919;response to stress#GO:0006950;reticulophagy#GO:0061709;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;autophagy#GO:0006914;catabolic process#GO:0009056;response to stimulus#GO:0050896;macroautophagy#GO:0016236 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000007159.4|UniProtKB=F6RD84 F6RD84 TTC9 PTHR11242:SF15 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 9A metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 cellular anatomical structure#GO:0110165;membrane#GO:0016020 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000005525.4|UniProtKB=F7FV45 F7FV45 SUSD1 PTHR24051:SF5 SUSHI DOMAIN-CONTAINING PROTEIN 1 SUSHI DOMAIN-CONTAINING PROTEIN 1 extracellular matrix glycoprotein#PC00100 MONDO|Ensembl=ENSMODG00000015544.4|UniProtKB=F6SKP2 F6SKP2 SMARCAL1 PTHR45766:SF6 DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER SNF2 RELATED CHROMATIN REMODELING ANNEALING HELICASE 1 ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974 intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228 DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000047787.1|UniProtKB=A0A5F8H5S5 A0A5F8H5S5 CCDC51 PTHR28624:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 51 MITOCHONDRIAL POTASSIUM CHANNEL MONDO|Ensembl=ENSMODG00000014799.4|UniProtKB=F7DMQ5 F7DMQ5 NAA16 PTHR22767:SF5 N-TERMINAL ACETYLTRANSFERASE-RELATED N-ALPHA-ACETYLTRANSFERASE 16, NATA AUXILIARY SUBUNIT enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000013180.4|UniProtKB=A0A5F8H3D1 A0A5F8H3D1 RPGRIP1L PTHR14240:SF4 RETINITIS PIGMENTOSA GTPASE REGULATOR-INTERACTING PROTEIN PROTEIN FANTOM protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cilium#GO:0005929;ciliary transition zone#GO:0035869;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010978.4|UniProtKB=F7APY3 F7APY3 SLC47A2 PTHR11206:SF81 MULTIDRUG RESISTANCE PROTEIN MULTIDRUG AND TOXIN EXTRUSION PROTEIN 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000014752.4|UniProtKB=A0A5F8H1W0 A0A5F8H1W0 LOC100032596 PTHR47901:SF3 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18 CASPASE-1 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175 biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;positive regulation of apoptotic process#GO:0043065;macromolecule metabolic process#GO:0043170;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;regulation of response to stress#GO:0080134;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;proteolysis#GO:0006508 canonical inflammasome complex#GO:0061702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000017714.4|UniProtKB=F7FHT6 F7FHT6 TPD52L1 PTHR19307:SF8 TUMOR PROTEIN D52 TUMOR PROTEIN D53 positive regulation of programmed cell death#GO:0043068;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;positive regulation of signaling#GO:0023056;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of biological process#GO:0048518;cell cycle G2/M phase transition#GO:0044839;cellular process#GO:0009987;regulation of JNK cascade#GO:0046328;positive regulation of apoptotic process#GO:0043065;regulation of MAPK cascade#GO:0043408;regulation of apoptotic process#GO:0042981;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G2/M transition of mitotic cell cycle#GO:0000086;cell cycle phase transition#GO:0044770;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;cell cycle#GO:0007049;positive regulation of signal transduction#GO:0009967;mitotic cell cycle phase transition#GO:0044772;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;mitotic cell cycle process#GO:1903047;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000005684.4|UniProtKB=F6V3I2 F6V3I2 TYK2 PTHR45807:SF6 TYROSINE-PROTEIN KINASE HOPSCOTCH NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672 response to stress#GO:0006950;response to hormone#GO:0009725;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;response to type II interferon#GO:0034341;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway via STAT#GO:0097696;cell surface receptor signaling pathway#GO:0007166;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to hormone stimulus#GO:0032870;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to peptide#GO:1901652;immune response#GO:0006955;cellular response to nitrogen compound#GO:1901699;response to other organism#GO:0051707;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;developmental process#GO:0032502;cellular developmental process#GO:0048869;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;response to external biotic stimulus#GO:0043207;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor tyrosine protein kinase#PC00168 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>JAK#P00846 MONDO|Ensembl=ENSMODG00000002140.3|UniProtKB=H9H5Z6 H9H5Z6 FKBP1B PTHR10516:SF429 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1B catalytic activity, acting on a protein#GO:0140096;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;catalytic activity#GO:0003824 regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of transport#GO:0051049;regulation of localization#GO:0032879;metabolic process#GO:0008152;regulation of multicellular organismal process#GO:0051239;intracellular signaling cassette#GO:0141124;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;signal transduction#GO:0007165;regulation of muscle contraction#GO:0006937;protein folding#GO:0006457;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of muscle system process#GO:0090257;calcium-mediated signaling#GO:0019722;macromolecule metabolic process#GO:0043170;regulation of system process#GO:0044057;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of calcium ion transport#GO:0051924;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;macromolecule biosynthetic process#GO:0009059;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;cell communication#GO:0007154;regulation of heart contraction#GO:0008016;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;cellular response to stimulus#GO:0051716;regulation of transmembrane transport#GO:0034762;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;sarcoplasm#GO:0016528;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;sarcoplasmic reticulum#GO:0016529;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;sarcoplasmic reticulum membrane#GO:0033017;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 MONDO|Ensembl=ENSMODG00000029019.2|UniProtKB=F6T450 F6T450 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000005311.3|UniProtKB=F7DM38 F7DM38 PTHR22902:SF17 SESQUIPEDALIAN SESQUIPEDALIAN-1 localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;cytosolic transport#GO:0016482;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;endosomal transport#GO:0016197;endosome organization#GO:0007032;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192 Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791;organelle subcompartment#GO:0031984;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000005965.3|UniProtKB=F6W064 F6W064 PTHR26452:SF806 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A16 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000029040.2|UniProtKB=K7E4M5 K7E4M5 RTBDN PTHR10517:SF19 FOLATE RECEPTOR RETBINDIN small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;molecular transducer activity#GO:0060089;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;heterocyclic compound binding#GO:1901363;signaling receptor activity#GO:0038023 establishment of localization#GO:0051234;vitamin transport#GO:0051180;localization#GO:0051179;nitrogen compound transport#GO:0071705;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000043369.1|UniProtKB=A0A5F8HA08 A0A5F8HA08 PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN antigen binding#GO:0003823;peptide binding#GO:0042277;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000010748.2|UniProtKB=F7FWU0 F7FWU0 STAR PTHR46489:SF1 STEROIDOGENIC ACUTE REGULATORY PROTEIN, MITOCHONDRIAL STEROIDOGENIC ACUTE REGULATORY PROTEIN, MITOCHONDRIAL MONDO|Ensembl=ENSMODG00000019555.4|UniProtKB=F6UTD5 F6UTD5 RHCG PTHR11730:SF30 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER RH TYPE C passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;transport#GO:0006810;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592;cellular process#GO:0009987;nitrogen compound transport#GO:0071705 apical part of cell#GO:0045177;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;apical plasma membrane#GO:0016324;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000003828.3|UniProtKB=A0A5F8GA32 A0A5F8GA32 THTPA PTHR14586:SF1 THIAMINE-TRIPHOSPHATASE THIAMINE-TRIPHOSPHATASE magnesium ion binding#GO:0000287;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ion binding#GO:0043167;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 Thiamin metabolism#P02780>Thiamine triphosphatase#P03184 MONDO|Ensembl=ENSMODG00000002571.2|UniProtKB=F7GF92 F7GF92 BEST4 PTHR10736:SF55 BESTROPHIN BESTROPHIN-4 monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000014262.4|UniProtKB=F7GCI5 F7GCI5 CALB2 PTHR19972:SF4 CALBINDIN CALRETININ calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;neuron projection terminus#GO:0044306;cell projection#GO:0042995;cell junction#GO:0030054;axon terminus#GO:0043679;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;cytosol#GO:0005829;nucleus#GO:0005634;presynapse#GO:0098793;neuron projection#GO:0043005 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000024082.2|UniProtKB=F7GGF2 F7GGF2 MPLKIP PTHR22446:SF3 M-PHASE-SPECIFIC PLK1-INTERACTING PROTEIN M-PHASE-SPECIFIC PLK1-INTERACTING PROTEIN nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;midbody#GO:0030496;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000016615.4|UniProtKB=A0A5F8HIX9 A0A5F8HIX9 PHACTR3 PTHR12751:SF7 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 3 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840 phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000041673.1|UniProtKB=A0A5F8H0J6 A0A5F8H0J6 PRSS23 PTHR15462:SF10 SERINE PROTEASE SERINE PROTEASE 23 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000017881.4|UniProtKB=F6YHF2 F6YHF2 LAMA4 PTHR15036:SF47 PIKACHURIN-LIKE PROTEIN LAMININ SUBUNIT ALPHA-4 animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;developmental process#GO:0032502;multicellular organism development#GO:0007275;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501 cell junction#GO:0030054;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;membrane#GO:0016020;basement membrane#GO:0005604;cell periphery#GO:0071944 cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Laminin#P00947 MONDO|Ensembl=ENSMODG00000050582.1|UniProtKB=A0A5F8HAC5 A0A5F8HAC5 PTHR11224:SF39 MAKORIN-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000018250.2|UniProtKB=F6PFV7 F6PFV7 HMGB4 PTHR48112:SF7 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B4 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 MONDO|Ensembl=ENSMODG00000023609.2|UniProtKB=F7EWW2 F7EWW2 BLCAP PTHR13259:SF1 BLADDER CANCER 10 KD PROTEIN HOMOLOG APOPTOSIS INDUCING FACTOR BLCAP MONDO|Ensembl=ENSMODG00000012291.4|UniProtKB=A0A5F8G4D2 A0A5F8G4D2 MBP PTHR11429:SF0 MYELIN BASIC PROTEIN MYELIN BASIC PROTEIN multicellular organismal process#GO:0032501;membrane organization#GO:0061024;nervous system development#GO:0007399;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;system development#GO:0048731;myelination#GO:0042552;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 neuron projection#GO:0043005;main axon#GO:0044304;cell body#GO:0044297;neuronal cell body#GO:0043025;cell projection#GO:0042995;myelin sheath#GO:0043209;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;axon#GO:0030424 structural protein#PC00211;myelin protein#PC00161 MONDO|Ensembl=ENSMODG00000007685.4|UniProtKB=A0A5F8GM69 A0A5F8GM69 PTHR10480:SF8 PROTEIN UNC-13 HOMOLOG PROTEIN UNC-13 HOMOLOG B protein binding#GO:0005515;syntaxin binding#GO:0019905;calmodulin binding#GO:0005516;SNARE binding#GO:0000149;binding#GO:0005488 trans-synaptic signaling#GO:0099537;organelle localization#GO:0051640;signal release#GO:0023061;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;anterograde trans-synaptic signaling#GO:0098916;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;calcium-ion regulated exocytosis#GO:0017156;establishment of localization#GO:0051234;vesicle localization#GO:0051648;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;export from cell#GO:0140352;signaling#GO:0023052;establishment of organelle localization#GO:0051656;exocytic process#GO:0140029;regulated exocytosis#GO:0045055;protein-containing complex organization#GO:0043933;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;neurotransmitter transport#GO:0006836;establishment of vesicle localization#GO:0051650;synaptic transmission, glutamatergic#GO:0035249;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;intracellular vesicle#GO:0097708;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;synaptic membrane#GO:0097060;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;neuron projection#GO:0043005;presynapse#GO:0098793;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;axon#GO:0030424;neuron projection terminus#GO:0044306;intracellular membrane-bounded organelle#GO:0043231;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;terminal bouton#GO:0043195;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;neuromuscular junction#GO:0031594;organelle membrane#GO:0031090;axon terminus#GO:0043679;plasma membrane region#GO:0098590;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944 Synaptic vesicle trafficking#P05734>Munc13#P05773 MONDO|Ensembl=ENSMODG00000011016.5|UniProtKB=A0A5F8HGP2 A0A5F8HGP2 SH3PXD2A PTHR15706:SF30 SH3 MULTIPLE DOMAIN SH3 AND PX DOMAIN-CONTAINING PROTEIN 2A enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;superoxide metabolic process#GO:0006801 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000012225.3|UniProtKB=A0A5F8GKP4 A0A5F8GKP4 PTHR33690:SF2 DUF4605 DOMAIN-CONTAINING PROTEIN PROTEIN FAM241B membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000003212.3|UniProtKB=F6TZ95 F6TZ95 PELI1 PTHR12098:SF4 E3 UBIQUITIN-PROTEIN LIGASE PELLINO-RELATED E3 UBIQUITIN-PROTEIN LIGASE PELLINO HOMOLOG 1 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000025201.3|UniProtKB=F7C0M3 F7C0M3 PTHR24376:SF38 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 544-RELATED gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000000984.4|UniProtKB=K7E5P2 K7E5P2 B9D1 PTHR12968:SF1 B9 DOMAIN-CONTAINING B9 DOMAIN-CONTAINING PROTEIN 1 cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000038121.1|UniProtKB=A0A5F8GK70 A0A5F8GK70 PTHR21633:SF10 IQ MOTIF CONTAINING F IQ MOTIF CONTAINING F4 MONDO|Ensembl=ENSMODG00000039546.1|UniProtKB=K7DZP0 K7DZP0 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000005286.4|UniProtKB=F7E6T7 F7E6T7 ATF7IP2 PTHR23210:SF23 ACTIVATING TRANSCRIPTION FACTOR 7 INTERACTING PROTEIN ACTIVATING TRANSCRIPTION FACTOR 7-INTERACTING PROTEIN 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000006708.4|UniProtKB=F7DGW4 F7DGW4 TTYH2 PTHR12424:SF6 TWEETY-RELATED PROTEIN TWEETY HOMOLOG 2 monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000045736.1|UniProtKB=A0A5F8H5C7 A0A5F8H5C7 PTHR24232:SF83 G-PROTEIN COUPLED RECEPTOR GENE 5127-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000042933.1|UniProtKB=A0A5F8GPC9 A0A5F8GPC9 LY6G6C PTHR32149:SF2 LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G6C LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G6C MONDO|Ensembl=ENSMODG00000036432.1|UniProtKB=A0A5F8GC63 A0A5F8GC63 PTHR26452:SF52 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013418.5|UniProtKB=A0A5F8HKK8 A0A5F8HKK8 HNRNPL PTHR15592:SF20 MATRIN 3/NUCLEAR PROTEIN 220-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000011763.3|UniProtKB=F7CWB7 F7CWB7 TMUB2 PTHR14557:SF4 PROTEIN C7ORF21 TRANSMEMBRANE AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN 2 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 MONDO|Ensembl=ENSMODG00000009996.4|UniProtKB=F6USA8 F6USA8 SNRNP48 PTHR21402:SF15 GAMETOCYTE SPECIFIC FACTOR 1-RELATED U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000002206.4|UniProtKB=F7G3M8 F7G3M8 TDG PTHR12159:SF9 G/T AND G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE G_T MISMATCH-SPECIFIC THYMINE DNA GLYCOSYLASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA N-glycosylase activity#GO:0019104 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;DNA glycosylase#PC00010 MONDO|Ensembl=ENSMODG00000049802.1|UniProtKB=A0A5F8GZB1 A0A5F8GZB1 PTHR48018:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 974 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000047636.1|UniProtKB=A0A5F8GDL9 A0A5F8GDL9 PTHR19446:SF479 REVERSE TRANSCRIPTASES RNA-DIRECTED DNA POLYMERASE viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000015906.3|UniProtKB=F7AFR9 F7AFR9 UBXN10 PTHR23322:SF28 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 10 ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006948.4|UniProtKB=F6RFY4 F6RFY4 PTHR11437:SF24 RIBONUCLEASE RIBONUCLEASE PANCREATIC catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518 response to external stimulus#GO:0009605;defense response#GO:0006952;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to Gram-positive bacterium#GO:0050830;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 endoribonuclease#PC00094;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000004553.3|UniProtKB=A0A5F8HGK7 A0A5F8HGK7 UBE3B PTHR45700:SF3 UBIQUITIN-PROTEIN LIGASE E3C UBIQUITIN-PROTEIN LIGASE E3B catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490 MONDO|Ensembl=ENSMODG00000004959.4|UniProtKB=A0A5F8GP09 A0A5F8GP09 SUSD4 PTHR47007:SF1 SUSHI DOMAIN-CONTAINING PROTEIN 4 SUSHI DOMAIN-CONTAINING PROTEIN 4 MONDO|Ensembl=ENSMODG00000005314.2|UniProtKB=F7DLL5 F7DLL5 ATP5F1D PTHR13822:SF7 ATP SYNTHASE DELTA/EPSILON CHAIN ATP SYNTHASE F(1) COMPLEX SUBUNIT DELTA, MITOCHONDRIAL proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;ligase activity#GO:0016874;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate biosynthetic process#GO:1901293;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;organophosphate biosynthetic process#GO:0090407;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate biosynthetic process#GO:0046390;ATP biosynthetic process#GO:0006754;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152 proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex#GO:0098803;membrane#GO:0016020;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;proton-transporting ATP synthase complex#GO:0045259 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000018611.4|UniProtKB=H9H752 H9H752 RFC2 PTHR11669:SF5 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 2 ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094 macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;DNA replication#GO:0006260;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950 replication fork#GO:0005657;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 MONDO|Ensembl=ENSMODG00000048388.1|UniProtKB=A0A5F8GJK6 A0A5F8GJK6 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000017620.5|UniProtKB=A0A5F8HEA1 A0A5F8HEA1 NPAS3 PTHR23043:SF30 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA NEURONAL PAS DOMAIN-CONTAINING PROTEIN 3 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000003277.2|UniProtKB=F7EGJ8 F7EGJ8 MGAT1 PTHR10468:SF12 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1/ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000003146.3|UniProtKB=F6WU16 F6WU16 SRSF9 PTHR23147:SF59 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 9 nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;membraneless organelle#GO:0043228 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000012332.4|UniProtKB=F7E2N5 F7E2N5 ZNF407 PTHR24403:SF60 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 407 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000044972.1|UniProtKB=A0A5F8H0A2 A0A5F8H0A2 PTHR24302:SF38 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A5 catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 steroid metabolic process#GO:0008202;lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000025736.3|UniProtKB=F6T224 F6T224 PTHR16431:SF3 NEUROGENIC PROTEIN MASTERMIND PROTEIN MIS18-BETA chromatin organization#GO:0006325;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;kinetochore organization#GO:0051383;cellular component organization or biogenesis#GO:0071840;kinetochore assembly#GO:0051382;organelle assembly#GO:0070925 intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000010060.3|UniProtKB=F6Y5A2 F6Y5A2 PTHR26451:SF404 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000001198.4|UniProtKB=F7GH48 F7GH48 PTPRT PTHR19134:SF208 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE T protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008 protein phosphatase#PC00195;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000018863.4|UniProtKB=F7DVG9 F7DVG9 LOC100014936 PTHR45813:SF6 IG-LIKE DOMAIN-CONTAINING PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR F2P-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000013386.3|UniProtKB=F7DSV4 F7DSV4 NXNL2 PTHR46762:SF1 NUCLEOREDOXIN-LIKE PROTEIN 2 NUCLEOREDOXIN-LIKE PROTEIN 2 sensory perception of light stimulus#GO:0050953;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;visual perception#GO:0007601;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000039100.1|UniProtKB=A0A5F8HHY2 A0A5F8HHY2 RNF228 PTHR22791:SF17 RING-TYPE DOMAIN-CONTAINING PROTEIN RING FINGER PROTEIN 228 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000000443.4|UniProtKB=A0A5F8H4E1 A0A5F8H4E1 TRIM33 PTHR45915:SF3 TRANSCRIPTION INTERMEDIARY FACTOR E3 UBIQUITIN-PROTEIN LIGASE TRIM33 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;transcription regulator activity#GO:0140110;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000050180.1|UniProtKB=F6TIL2 F6TIL2 LOC100618316 PTHR26450:SF351 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028915.1|UniProtKB=K7E0R8 K7E0R8 PTHR47326:SF2 TRANSPOSABLE ELEMENT TC3 TRANSPOSASE-LIKE PROTEIN DUF4817 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000666.5|UniProtKB=F6QFY9 F6QFY9 ORC1 PTHR10763:SF23 CELL DIVISION CONTROL PROTEIN 6-RELATED ORIGIN RECOGNITION COMPLEX SUBUNIT 1 DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA replication origin binding#GO:0003688;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;chromosome#GO:0005694;nuclear protein-containing complex#GO:0140513;origin recognition complex#GO:0000808;membraneless organelle#GO:0043228;nuclear origin of replication recognition complex#GO:0005664;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 replication origin binding protein#PC00199 MONDO|Ensembl=ENSMODG00000015165.5|UniProtKB=F7CEU5 F7CEU5 SPEG PTHR47633:SF3 IMMUNOGLOBULIN STRIATED MUSCLE PREFERENTIALLY EXPRESSED PROTEIN KINASE muscle structure development#GO:0061061;cell differentiation#GO:0030154;cellular process#GO:0009987;muscle cell differentiation#GO:0042692;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 MONDO|Ensembl=ENSMODG00000009770.4|UniProtKB=A0A5F8GD95 A0A5F8GD95 PISD PTHR10067:SF6 PHOSPHATIDYLSERINE DECARBOXYLASE PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;lyase#PC00144;decarboxylase#PC00089 MONDO|Ensembl=ENSMODG00000014812.4|UniProtKB=A0A5F8GU37 A0A5F8GU37 PTHR21577:SF4 SHUGOSHIN SHUGOSHIN 1 chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;meiotic sister chromatid cohesion#GO:0051177;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;meiotic nuclear division#GO:0140013;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;mitotic sister chromatid cohesion#GO:0007064;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;sister chromatid cohesion#GO:0007062;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;meiosis I#GO:0007127;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;reproductive process#GO:0022414 intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775 centromere DNA-binding protein#PC00071 MONDO|Ensembl=ENSMODG00000004329.2|UniProtKB=F6X6S7 F6X6S7 SLC30A10 PTHR45820:SF3 FI23527P1 CALCIUM_MANGANESE ANTIPORTER SLC30A10 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075 intracellular monoatomic ion homeostasis#GO:0006873;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;metal ion transport#GO:0030001;homeostatic process#GO:0042592;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;response to stress#GO:0006950;monoatomic ion homeostasis#GO:0050801;detoxification of inorganic compound#GO:0061687;cellular process#GO:0009987;response to chemical#GO:0042221;detoxification#GO:0098754;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;response to metal ion#GO:0010038;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000018934.4|UniProtKB=F7GJQ1 F7GJQ1 EXOSC9 PTHR11097:SF14 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP45 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;snRNA 3'-end processing#GO:0034472;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of metabolic process#GO:0009892;maturation of 5.8S rRNA#GO:0000460;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;mRNA catabolic process#GO:0006402;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;snRNA metabolic process#GO:0016073;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;snRNA processing#GO:0016180;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;nuclear mRNA surveillance#GO:0071028;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;exoribonuclease#PC00099 MONDO|Ensembl=ENSMODG00000000521.4|UniProtKB=A0A5F8GFT9 A0A5F8GFT9 SKAP2 PTHR15129:SF2 SRC-ASSOCIATED ADAPTOR PROTEIN SRC KINASE-ASSOCIATED PHOSPHOPROTEIN 2 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000008031.4|UniProtKB=F7G1E0 F7G1E0 PTHR24377:SF980 IP01015P-RELATED ZINC FINGER PROTEIN 420 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000012666.4|UniProtKB=F6VXM6 F6VXM6 GBGT1 PTHR10462:SF49 GLYCOSYLTRANSFERASE-RELATED GLOBOSIDE ALPHA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000005916.3|UniProtKB=F6XCT8 F6XCT8 RIN2 PTHR23101:SF51 RAB GDP/GTP EXCHANGE FACTOR RAS AND RAB INTERACTOR 2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;cytosol#GO:0005829;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000023534.2|UniProtKB=F7GLB6 F7GLB6 PTHR21454:SF31 DPH3 HOMOLOG-RELATED DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3 iron ion binding#GO:0005506;metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914 cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000003467.4|UniProtKB=F7DBI9 F7DBI9 LOC100019732 PTHR16095:SF10 TRANSMEMBRANE PROTEIN 143 FAMILY MEMBER TRANSMEMBRANE PROTEIN 143 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000023319.2|UniProtKB=F6RSE5 F6RSE5 LOC100031146 PTHR24249:SF79 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 9 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000040837.1|UniProtKB=A0A5F8GYE0 A0A5F8GYE0 PTHR48018:SF28 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8K3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007631.4|UniProtKB=F7BKM4 F7BKM4 HMMR PTHR18956:SF6 HYALURONAN MEDIATED MOTILITY RECEPTOR HYALURONAN MEDIATED MOTILITY RECEPTOR MONDO|Ensembl=ENSMODG00000008045.4|UniProtKB=A0A5F8GZ01 A0A5F8GZ01 FAM219A PTHR31281:SF0 PROTEIN FAM219A PROTEIN FAM219A MONDO|Ensembl=ENSMODG00000011331.4|UniProtKB=F6WI20 F6WI20 E2F3 PTHR12081:SF44 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F3 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 p53 pathway feedback loops 2#P04398>E2F-1#P04652;p53 pathway#P00059>E2F-1#P04627;Cell cycle#P00013>E2F#P00488 MONDO|Ensembl=ENSMODG00000014882.4|UniProtKB=F7GGJ7 F7GGJ7 TPM4 PTHR19269:SF70 TROPOMYOSIN TROPOMYOSIN ALPHA-4 CHAIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 muscle contraction#GO:0006936;actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;system process#GO:0003008;cellular component organization or biogenesis#GO:0071840;muscle system process#GO:0003012;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232 actin binding motor protein#PC00040 MONDO|Ensembl=ENSMODG00000040168.1|UniProtKB=A0A5F8GSB4 A0A5F8GSB4 PTHR24068:SF70 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 E1 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein K48-linked ubiquitination#GO:0070936;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;ISG15-protein conjugation#GO:0032020 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000009148.3|UniProtKB=A0A5F8H7W3 A0A5F8H7W3 PTHR10885:SF24 ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;metabolic process#GO:0008152;isoprenoid biosynthetic process#GO:0008299;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407;isoprenoid metabolic process#GO:0006720 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579 isomerase#PC00135 MONDO|Ensembl=ENSMODG00000038490.1|UniProtKB=F6Q1P0 F6Q1P0 LOC100023588 PTHR26450:SF194 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52N4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009449.3|UniProtKB=F7FZL7 F7FZL7 ARL5B PTHR11711:SF146 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 5B guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553 macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein localization to membrane#GO:0072657;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802 G-protein#PC00020 MONDO|Ensembl=ENSMODG00000003846.4|UniProtKB=F7EBM0 F7EBM0 LOC100016373 PTHR16222:SF23 ADP-RIBOSYLGLYCOHYDROLASE INACTIVE ADP-RIBOSYLTRANSFERASE ARH2 catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000023352.1|UniProtKB=F6TRX0 F6TRX0 GPR6 PTHR22750:SF19 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 6 bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000051277.1|UniProtKB=A0A5F8GH96 A0A5F8GH96 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000014555.4|UniProtKB=A0A5F8GYA3 A0A5F8GYA3 ZC3H12C PTHR12876:SF36 N4BP1-RELATED RIBONUCLEASE ZC3H12C-RELATED RNA binding#GO:0003723;nuclease activity#GO:0004518;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;nucleus#GO:0005634 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000019086.4|UniProtKB=F6VLD3 F6VLD3 PTHR12385:SF42 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 5 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000025019.2|UniProtKB=F6SW05 F6SW05 LOC100016133 PTHR11717:SF35 LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000006290.4|UniProtKB=F7CAF0 F7CAF0 INTS11 PTHR11203:SF37 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER INTEGRATOR COMPLEX SUBUNIT 11 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000036450.1|UniProtKB=A0A5F8H5D7 A0A5F8H5D7 PTHR45880:SF1 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;U2 snRNP#GO:0005686;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681 MONDO|Ensembl=ENSMODG00000012086.3|UniProtKB=F7G4Q4 F7G4Q4 ANGPT2 PTHR19143:SF199 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-2 receptor tyrosine kinase binding#GO:0030971;protein binding#GO:0005515;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;multicellular organismal process#GO:0032501;tube development#GO:0035295;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;cell communication#GO:0007154;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;response to stimulus#GO:0050896;signaling#GO:0023052;blood vessel morphogenesis#GO:0048514;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Angiogenesis#P00005>Ang-2#P00246 MONDO|Ensembl=ENSMODG00000023239.1|UniProtKB=F6UCV5 F6UCV5 KCNA2 PTHR11537:SF23 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 2 potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;metal ion transport#GO:0030001;action potential#GO:0001508;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;presynapse#GO:0098793;main axon#GO:0044304;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;cell junction#GO:0030054;axon terminus#GO:0043679;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;synapse#GO:0045202;cellular anatomical structure#GO:0110165;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;neuron projection terminus#GO:0044306;cell projection#GO:0042995;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;transmembrane transporter complex#GO:1902495 voltage-gated ion channel#PC00241;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000005296.4|UniProtKB=F7DMP5 F7DMP5 SERPINB5 PTHR11461:SF55 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B5 peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 p53 pathway#P00059>Maspin#G01569 MONDO|Ensembl=ENSMODG00000020270.2|UniProtKB=F7C199 F7C199 LOC100031249 PTHR12612:SF48 NUCLEAR TRANSPORT FACTOR 2 NUCLEAR TRANSPORT FACTOR 2 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein localization to organelle#GO:0033365;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nucleocytoplasmic transport#GO:0006913 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000020744.4|UniProtKB=F7A010 F7A010 TMPRSS11D PTHR24253:SF45 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 11D serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000014611.4|UniProtKB=F7FH88 F7FH88 PTHR21469:SF4 EXOPHILIN-5 EXOPHILIN-5 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 cell communication#GO:0007154;regulation of secretion#GO:0051046;localization#GO:0051179;regulation of secretion by cell#GO:1903530;intracellular signal transduction#GO:0035556;regulation of exocytosis#GO:0017157;positive regulation of secretion#GO:0051047;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;establishment of localization#GO:0051234;regulation of transport#GO:0051049;regulation of localization#GO:0032879;transport#GO:0006810;vesicle-mediated transport#GO:0016192;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;positive regulation of cellular process#GO:0048522;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;signal transduction#GO:0007165;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000013467.4|UniProtKB=F7FMY3 F7FMY3 ANKMY1 PTHR15897:SF2 ANKYRIN REPEAT AND MYND DOMAIN PROTEIN 1 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000001181.3|UniProtKB=F7GHD0 F7GHD0 LOC100011591 PTHR26454:SF167 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000044657.1|UniProtKB=A0A5F8H4M7 A0A5F8H4M7 ATP6V0E1 PTHR12263:SF5 VACUOLAR ATP SYNTHASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT E 1 monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 monoatomic ion transport#GO:0006811;localization#GO:0051179;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane#GO:0016020;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469 primary active transporter#PC00068;ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000040155.1|UniProtKB=F6TF89 F6TF89 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000019196.4|UniProtKB=F7A8T9 F7A8T9 ADAP2 PTHR46021:SF6 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 2 phosphatidylinositol phosphate binding#GO:1901981;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;phospholipid binding#GO:0005543;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;lipid binding#GO:0008289;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;heart development#GO:0007507;circulatory system development#GO:0072359 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000009687.4|UniProtKB=F6YBJ3 F6YBJ3 PTHR10585:SF33 ER LUMEN PROTEIN RETAINING RECEPTOR ER LUMEN PROTEIN-RETAINING RECEPTOR 3 signal sequence receptor activity#GO:0005048 localization#GO:0051179;protein localization to organelle#GO:0033365;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987 cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000019578.4|UniProtKB=F6QN15 F6QN15 TMEM268 PTHR31193:SF1 TRANSMEMBRANE PROTEIN C9ORF91 TRANSMEMBRANE PROTEIN 268 MONDO|Ensembl=ENSMODG00000024730.2|UniProtKB=F7EF75 F7EF75 PTHR19424:SF3 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR-BINDING PROTEIN 1 cellular response to heat#GO:0034605;response to heat#GO:0009408;heat acclimation#GO:0010286;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to temperature stimulus#GO:0009266;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000004546.4|UniProtKB=F6R5L7 F6R5L7 FAM181B PTHR33766:SF2 PROTEIN FAM181B PROTEIN FAM181B MONDO|Ensembl=ENSMODG00000020051.3|UniProtKB=F6ZGB3 F6ZGB3 LOC100617117 PTHR48018:SF109 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8U3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000047397.1|UniProtKB=A0A5F8HKG5 A0A5F8HKG5 LOC100618787 PTHR26453:SF116 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2F1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007847.4|UniProtKB=F6Y0B4 F6Y0B4 ZEB1 PTHR24391:SF17 HISTONE H4 TRANSCRIPTION FACTOR-RELATED ZINC FINGER E-BOX-BINDING HOMEOBOX 1 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 Gonadotropin-releasing hormone receptor pathway#P06664>Zeb1#G06670;Gonadotropin-releasing hormone receptor pathway#P06664>Zeb1#G06884;Gonadotropin-releasing hormone receptor pathway#P06664>Zeb1#P06783 MONDO|Ensembl=ENSMODG00000019862.4|UniProtKB=F6RR92 F6RR92 HSD17B12 PTHR43899:SF14 RH59310P VERY-LONG-CHAIN 3-OXOACYL-COA REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000006272.4|UniProtKB=A0A5F8GYJ1 A0A5F8GYJ1 TPP2 PTHR43806:SF14 PEPTIDASE S8 TRIPEPTIDYL-PEPTIDASE 2 catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000012460.5|UniProtKB=F6PHT3 F6PHT3 UCK1 PTHR10285:SF66 URIDINE KINASE URIDINE-CYTIDINE KINASE 1 nucleoside kinase activity#GO:0019206;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137;nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156 MONDO|Ensembl=ENSMODG00000036833.1|UniProtKB=F7AN03 F7AN03 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000014619.4|UniProtKB=F6ZDE6 F6ZDE6 PTHR32017:SF3 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 2 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 2 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cell cycle#GO:0007049;chromosome segregation#GO:0007059;cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic cell cycle#GO:0000278 cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;outer kinetochore#GO:0000940;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;supramolecular fiber#GO:0099512;chromosome#GO:0005694;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000015751.2|UniProtKB=F7AH47 F7AH47 CDIPT PTHR15362:SF4 PHOSPHATIDYLINOSITOL SYNTHASE CDP-DIACYLGLYCEROL--INOSITOL 3-PHOSPHATIDYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220 MONDO|Ensembl=ENSMODG00000003023.4|UniProtKB=F6Q219 F6Q219 CBFA2T2 PTHR10379:SF13 MTG8 ETO EIGHT TWENTY ONE PROTEIN PROTEIN CBFA2T2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000015359.3|UniProtKB=A0A5F8H8P4 A0A5F8H8P4 CDK5R2 PTHR23401:SF3 CYCLIN DEPENDANT KINASE-5 ACTIVATOR CYCLIN-DEPENDENT KINASE 5 ACTIVATOR 2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;protein kinase activator activity#GO:0030295;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase activator activity#GO:0019209 neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;axon development#GO:0061564;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;brain development#GO:0007420;system development#GO:0048731;anatomical structure development#GO:0048856;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;head development#GO:0060322;nervous system development#GO:0007399;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;central nervous system development#GO:0007417 neuron projection#GO:0043005;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;growth cone#GO:0030426;axon#GO:0030424;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427 kinase activator#PC00138;kinase modulator#PC00140 MONDO|Ensembl=ENSMODG00000004481.4|UniProtKB=F6VRF8 F6VRF8 ARHGEF7 PTHR46026:SF3 RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 7 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cellular process#GO:0009987;cell projection assembly#GO:0030031;lamellipodium assembly#GO:0030032;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840 cell leading edge#GO:0031252;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000000804.4|UniProtKB=F6S9V4 F6S9V4 FAM184B PTHR18870:SF8 PROTEIN TAG-278-RELATED PROTEIN FAM184B MONDO|Ensembl=ENSMODG00000014778.5|UniProtKB=F7EKF0 F7EKF0 VEZF1 PTHR24379:SF75 KRAB AND ZINC FINGER DOMAIN-CONTAINING VASCULAR ENDOTHELIAL ZINC FINGER 1 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000047591.1|UniProtKB=A0A5F8HAX4 A0A5F8HAX4 PTHR48595:SF1 FAMILY NOT NAMED RIKEN CDNA 2010106E10 GENE MONDO|Ensembl=ENSMODG00000007531.4|UniProtKB=F7GJL0 F7GJL0 GBX2 PTHR24334:SF3 HOMEOBOX PROTEIN GBX HOMEOBOX PROTEIN GBX-2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000029779.2|UniProtKB=K7E0L5 K7E0L5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000011407.3|UniProtKB=F6S5R1 F6S5R1 SNRNP27 PTHR31077:SF1 U4/U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN U4_U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000011828.3|UniProtKB=F7GLZ9 F7GLZ9 C1orf146 PTHR31408:SF2 HYPOTHETICAL PROTEIN LOC689986 PROTEIN SPO16 HOMOLOG meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;synaptonemal complex assembly#GO:0007130;cellular component assembly#GO:0022607;homologous chromosome pairing at meiosis#GO:0007129;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;reciprocal homologous recombination#GO:0140527;reproductive process#GO:0022414;homologous recombination#GO:0035825;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;nucleobase-containing compound metabolic process#GO:0006139;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132 intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000013294.4|UniProtKB=F6ZK61 F6ZK61 PTHR38495:SF1 MCG11474 RIKEN CDNA 1700001K19 GENE MONDO|Ensembl=ENSMODG00000020420.4|UniProtKB=F7BDI7 F7BDI7 PDZD2 PTHR11324:SF16 IL16-RELATED PDZ DOMAIN-CONTAINING PROTEIN 2 cytokine#PC00083;interleukin superfamily#PC00128 MONDO|Ensembl=ENSMODG00000019189.4|UniProtKB=F7FMB3 F7FMB3 RHOT1 PTHR24072:SF124 RHO FAMILY GTPASE MITOCHONDRIAL RHO GTPASE 1 purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787 actin filament-based process#GO:0030029;organelle localization#GO:0051640;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;localization#GO:0051179;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;actin cytoskeleton organization#GO:0030036;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;transport#GO:0006810;intracellular transport#GO:0046907;actin filament organization#GO:0007015;mitochondrion localization#GO:0051646;apoptotic signaling pathway#GO:0097190;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;biological regulation#GO:0065007;regulation of mitochondrial membrane permeability#GO:0046902;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based transport#GO:0099111;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cellular component organization#GO:0016043;signaling#GO:0023052;response to stimulus#GO:0050896;establishment of organelle localization#GO:0051656;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;organelle transport along microtubule#GO:0072384;regulation of membrane permeability#GO:0090559 outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cell periphery#GO:0071944;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000027595.1|UniProtKB=K7E173 K7E173 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013353.4|UniProtKB=F7GA57 F7GA57 MLH1 PTHR10073:SF57 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL DNA MISMATCH REPAIR PROTEIN MLH1 endonuclease activity#GO:0004519;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 somatic diversification of immune receptors#GO:0002200;mismatch repair#GO:0006298;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;production of molecular mediator of immune response#GO:0002440;cellular response to stress#GO:0033554;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;immune system development#GO:0002520;anatomical structure development#GO:0048856;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;multicellular organismal process#GO:0032501;DNA damage response#GO:0006974;developmental process#GO:0032502;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000006302.4|UniProtKB=F7BRN9 F7BRN9 PTBP1 PTHR15592:SF19 MATRIN 3/NUCLEAR PROTEIN 220-RELATED POLYPYRIMIDINE TRACT-BINDING PROTEIN 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cell differentiation#GO:0045595;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of RNA splicing#GO:0043484;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000016221.4|UniProtKB=F7FM02 F7FM02 GDAP1L1 PTHR44188:SF2 GDAP1, ISOFORM A GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 1-LIKE 1 cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;cellular process#GO:0009987;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;organelle fusion#GO:0048284;mitochondrial fission#GO:0000266 mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000021139.3|UniProtKB=H9H7V0 H9H7V0 LOC103103209 PTHR22750:SF56 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000025415.1|UniProtKB=F6QFE4 F6QFE4 PTHR22847:SF751 WD40 REPEAT PROTEIN WD REPEAT DOMAIN 5B chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of transcription by RNA polymerase II#GO:0006357;DNA-templated transcription initiation#GO:0006352;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;transcription initiation at RNA polymerase II promoter#GO:0006367;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;transcription initiation-coupled chromatin remodeling#GO:0045815;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;transcription by RNA polymerase II#GO:0006366 transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Set1C/COMPASS complex#GO:0048188;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;NSL complex#GO:0044545;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000023990.2|UniProtKB=F7DQ99 F7DQ99 LRRC3B PTHR24373:SF276 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 3B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004971.4|UniProtKB=F7FL55 F7FL55 MTF2 PTHR12628:SF12 POLYCOMB-LIKE TRANSCRIPTION FACTOR METAL-RESPONSE ELEMENT-BINDING TRANSCRIPTION FACTOR 2 nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;DNA binding#GO:0003677 negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000045899.1|UniProtKB=A0A5F8GXD0 A0A5F8GXD0 DNAJB1 PTHR24078:SF568 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 1 Hsp70 protein binding#GO:0030544;heat shock protein binding#GO:0031072;transcription coregulator activity#GO:0003712;protein-folding chaperone binding#GO:0051087;transcription corepressor activity#GO:0003714;protein binding#GO:0005515;transcription regulator activity#GO:0140110;binding#GO:0005488 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;protein folding#GO:0006457;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000005975.4|UniProtKB=F6VZD1 F6VZD1 PTHR24376:SF264 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 11 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000002105.3|UniProtKB=F6UGU9 F6UGU9 FANCL PTHR13206:SF0 UBIQUITIN LIGASE PROTEIN PHF9 FANCONI ANEMIA GROUP L PROTEIN E3 UBIQUITIN-PROTEIN LIGASE FANCL transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 response to stimulus#GO:0050896;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000014524.4|UniProtKB=F7ERL1 F7ERL1 CAPN7 PTHR46143:SF1 CALPAIN-7 CALPAIN-7 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 Huntington disease#P00029>Calpain#P00788 MONDO|Ensembl=ENSMODG00000038429.1|UniProtKB=A0A5F8GX09 A0A5F8GX09 FAM219B PTHR31281:SF2 PROTEIN FAM219A PROTEIN FAM219B MONDO|Ensembl=ENSMODG00000017050.4|UniProtKB=F6XZF3 F6XZF3 MATN1 PTHR24020:SF16 COLLAGEN ALPHA MATRILIN-1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000002861.4|UniProtKB=F7E2J7 F7E2J7 RBP7 PTHR11955:SF97 FATTY ACID BINDING PROTEIN RETINOID-BINDING PROTEIN 7 ion binding#GO:0043167;binding#GO:0005488;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;anion binding#GO:0043168;organic acid binding#GO:0043177;fatty acid binding#GO:0005504;lipid binding#GO:0008289 localization#GO:0051179;fatty acid transport#GO:0015908;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;lipid transport#GO:0006869;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000036741.1|UniProtKB=A0A5F8H6M9 A0A5F8H6M9 MAML2 PTHR15692:SF9 MASTERMIND-LIKE MASTERMIND-LIKE PROTEIN 2 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;positive regulation of transcription by RNA polymerase II#GO:0045944;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000011796.4|UniProtKB=F7CBS8 F7CBS8 GFPT1 PTHR10937:SF12 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING GLUTAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transaminase activity#GO:0008483 UDP-N-acetylglucosamine biosynthetic process#GO:0006048;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine metabolic process#GO:0006047;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 transaminase#PC00216 O-antigen biosynthesis#P02757>Fructose-6-phosphate aminotransferase#P03051;N-acetylglucosamine metabolism#P02756>Fructose-6-phosphate aminotransferase#P03042 MONDO|Ensembl=ENSMODG00000013826.4|UniProtKB=F6SEC3 F6SEC3 TRIM24 PTHR45915:SF4 TRANSCRIPTION INTERMEDIARY FACTOR TRANSCRIPTION INTERMEDIARY FACTOR 1-ALPHA aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transcription coactivator activity#GO:0003713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transcription coregulator activity#GO:0003712;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;transcription regulator activity#GO:0140110;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein stability#GO:0031647;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of biological quality#GO:0065008;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000013169.4|UniProtKB=F6ZLP4 F6ZLP4 DLK1 PTHR24052:SF11 DELTA-RELATED PROTEIN DELTA HOMOLOG 1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Delta#P01116;Angiogenesis#P00005>Delta/Serrate#P00226 MONDO|Ensembl=ENSMODG00000003740.5|UniProtKB=A0A5F8GYI5 A0A5F8GYI5 ANKRD11 PTHR24145:SF3 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 11 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 11 anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502 MONDO|Ensembl=ENSMODG00000007677.4|UniProtKB=F7FNG1 F7FNG1 PTHR12162:SF0 NIBRIN-RELATED NIBRIN damaged DNA binding#GO:0003684;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 double-strand break repair#GO:0006302;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;regulation of cell cycle process#GO:0010564;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;regulation of mitotic cell cycle phase transition#GO:1901990;cellular response to stress#GO:0033554;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;mitotic G2/M transition checkpoint#GO:0044818;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;recombinational repair#GO:0000725;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 MONDO|Ensembl=ENSMODG00000024246.2|UniProtKB=F7AJJ6 F7AJJ6 PTHR26452:SF253 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10Q1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000099.3|UniProtKB=A0A5F8GDY7 A0A5F8GDY7 CNTNAP5 PTHR15036:SF46 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN-LIKE 5 multicellular organism development#GO:0007275;developmental process#GO:0032502;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000051073.1|UniProtKB=A0A5F8GA34 A0A5F8GA34 JDP2 PTHR23351:SF10 FOS TRANSCRIPTION FACTOR-RELATED JUN DIMERIZATION PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302 MONDO|Ensembl=ENSMODG00000017067.4|UniProtKB=F6XHB9 F6XHB9 PUM1 PTHR12537:SF1 RNA BINDING PROTEIN PUMILIO-RELATED PUMILIO HOMOLOG 1 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of mRNA metabolic process#GO:1903311;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000015892.3|UniProtKB=F7AGN8 F7AGN8 ECI1 PTHR11941:SF178 ENOYL-COA HYDRATASE-RELATED ENOYL-COA DELTA ISOMERASE 1, MITOCHONDRIAL catalytic activity#GO:0003824;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 lyase#PC00144;hydratase#PC00120;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000044701.1|UniProtKB=A0A5F8GXU7 A0A5F8GXU7 PTHR23227:SF86 BUCENTAUR RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000006768.4|UniProtKB=A0A5F8GRJ8 A0A5F8GRJ8 PAPLN PTHR13723:SF281 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE PAPILIN catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 external encapsulating structure organization#GO:0045229;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000025420.2|UniProtKB=F6WI92 F6WI92 PTHR12297:SF5 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1A, MITOCHONDRIAL cellular component assembly#GO:0022607;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000012570.5|UniProtKB=A0A5F8GDN6 A0A5F8GDN6 ARHGAP23 PTHR23175:SF5 PDZ DOMAIN-CONTAINING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 23 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 MONDO|Ensembl=ENSMODG00000018739.2|UniProtKB=F7EFL2 F7EFL2 GJA5 PTHR11984:SF13 CONNEXIN GAP JUNCTION ALPHA-5 PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;circulatory system development#GO:0072359;regulation of heart contraction#GO:0008016;signaling#GO:0023052;regulation of biological process#GO:0050789;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of system process#GO:0044057;developmental process#GO:0032502;multicellular organismal process#GO:0032501;heart development#GO:0007507;regulation of multicellular organismal process#GO:0051239;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular process#GO:0009987 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell junction#GO:0030054 gap junction#PC00105;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000015436.4|UniProtKB=A0A5F8GEM1 A0A5F8GEM1 TBC1D24 PTHR23353:SF34 RAB-GAP/TBC-RELATED TBC1 DOMAIN FAMILY MEMBER 24 GTPase-activating protein#PC00257 N-acetylglucosamine metabolism#P02756>N-acetylglucosamine-6-phosphate deacetylase#P03036 MONDO|Ensembl=ENSMODG00000027869.2|UniProtKB=K7E4I7 K7E4I7 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020310.4|UniProtKB=F7G7P1 F7G7P1 C9 PTHR45742:SF3 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C9 humoral immune response#GO:0006959;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;positive regulation of immune system process#GO:0002684;complement activation#GO:0006956;activation of immune response#GO:0002253;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576 complement component#PC00078 MONDO|Ensembl=ENSMODG00000022637.3|UniProtKB=H9H897 H9H897 LOC100019002 PTHR11556:SF11 FRUCTOSE-1,6-BISPHOSPHATASE-RELATED FRUCTOSE-1,6-BISPHOSPHATASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;sugar-phosphatase activity#GO:0050308;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987;gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319;small molecule metabolic process#GO:0044281;carbohydrate biosynthetic process#GO:0016051;carbohydrate metabolic process#GO:0005975;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;glucose metabolic process#GO:0006006 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 hydrolase#PC00121;carbohydrate phosphatase#PC00066;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000006193.4|UniProtKB=A0A5F8GPR6 A0A5F8GPR6 RNASET2 PTHR11240:SF94 RIBONUCLEASE T2 RIBONUCLEASE T2 catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 RNA catabolic process#GO:0006401;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000039810.1|UniProtKB=A0A5F8G7N1 A0A5F8G7N1 LOC103096099 PTHR21859:SF12 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31D1 MONDO|Ensembl=ENSMODG00000038123.1|UniProtKB=A0A5F8GA49 A0A5F8GA49 BAD PTHR28540:SF1 BCL2-ASSOCIATED AGONIST OF CELL DEATH BCL2-ASSOCIATED AGONIST OF CELL DEATH peptidase activator activity#GO:0016504;peptidase regulator activity#GO:0061134;enzyme activator activity#GO:0008047;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;cell death#GO:0008219;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell communication#GO:0007154;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of apoptotic process#GO:0043065;apoptotic signaling pathway#GO:0097190 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 CCKR signaling map#P06959>BAD#P07210 MONDO|Ensembl=ENSMODG00000040797.1|UniProtKB=A0A5F8HAE9 A0A5F8HAE9 PTHR43599:SF8 MULTIFUNCTIONAL PROTEIN ADE2 SI:DKEY-261J15.2 ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;primary metabolic process#GO:0044238;IMP metabolic process#GO:0046040;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;nucleoside phosphate biosynthetic process#GO:1901293;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000007413.4|UniProtKB=A0A5F8GMC1 A0A5F8GMC1 UROC1 PTHR12216:SF3 UROCANATE HYDRATASE UROCANATE HYDRATASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 hydratase#PC00120 MONDO|Ensembl=ENSMODG00000023359.2|UniProtKB=F6Y2Z3 F6Y2Z3 PTHR18843:SF2 TORSIN-1A-INTERACTING PROTEIN TORSIN-1A-INTERACTING PROTEIN 2 endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000039857.1|UniProtKB=F7GGK2 F7GGK2 TPM1 PTHR19269:SF41 TROPOMYOSIN TROPOMYOSIN ALPHA-1 CHAIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;muscle contraction#GO:0006936;actin filament organization#GO:0007015;heart contraction#GO:0060047;system process#GO:0003008;cellular component organization or biogenesis#GO:0071840;muscle system process#GO:0003012;heart process#GO:0003015;cellular component organization#GO:0016043;striated muscle contraction#GO:0006941;actin cytoskeleton organization#GO:0030036;cardiac muscle contraction#GO:0060048;actin filament-based process#GO:0030029;circulatory system process#GO:0003013;supramolecular fiber organization#GO:0097435 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;actin filament#GO:0005884;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 actin binding motor protein#PC00040 MONDO|Ensembl=ENSMODG00000001446.4|UniProtKB=F6R2X3 F6R2X3 IRX2 PTHR11211:SF15 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;cell development#GO:0048468;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000010005.4|UniProtKB=F6ZE77 F6ZE77 KCNH6 PTHR10217:SF468 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED INWARDLY RECTIFYING POTASSIUM CHANNEL KCNH6 voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000008782.4|UniProtKB=F6RGL7 F6RGL7 SLC22A23 PTHR24064:SF192 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 23 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000011248.4|UniProtKB=F6RLV5 F6RLV5 ZDHHC3 PTHR22883:SF246 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC3 catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;protein targeting to membrane#GO:0006612;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;localization#GO:0051179;regulation of signaling#GO:0023051;localization within membrane#GO:0051668;regulation of cellular process#GO:0050794;protein targeting#GO:0006605;regulation of cell communication#GO:0010646;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000008806.3|UniProtKB=F6QB22 F6QB22 CDKL4 PTHR24056:SF120 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 4 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000005597.3|UniProtKB=F7DJA1 F7DJA1 IDS PTHR45953:SF1 IDURONATE 2-SULFATASE IDURONATE 2-SULFATASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000047217.1|UniProtKB=A0A5F8G9L3 A0A5F8G9L3 PTHR34769:SF1 RCG42593, ISOFORM CRA_A DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 MONDO|Ensembl=ENSMODG00000017432.3|UniProtKB=F6ZV76 F6ZV76 TSSK3 PTHR24343:SF74 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 3 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell differentiation#GO:0030154;gamete generation#GO:0007276;sexual reproduction#GO:0019953;spermatid development#GO:0007286;spermatid differentiation#GO:0048515;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;cellular process#GO:0009987;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000012485.4|UniProtKB=F6Q3K3 F6Q3K3 AOX1 PTHR11908:SF86 XANTHINE DEHYDROGENASE ALDEHYDE OXIDASE oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000005941.3|UniProtKB=F6WW41 F6WW41 PTHR10366:SF860 NAD DEPENDENT EPIMERASE/DEHYDRATASE STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;steroid metabolic process#GO:0008202;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;sterol metabolic process#GO:0016125 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;lyase#PC00144;dehydratase#PC00091 MONDO|Ensembl=ENSMODG00000009260.3|UniProtKB=F7DB63 F7DB63 AANAT PTHR10908:SF7 SEROTONIN N-ACETYLTRANSFERASE SEROTONIN N-ACETYLTRANSFERASE N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 response to abiotic stimulus#GO:0009628;rhythmic process#GO:0048511;photoperiodism#GO:0009648;response to radiation#GO:0009314;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;circadian rhythm#GO:0007623 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 acetyltransferase#PC00038;transferase#PC00220 MONDO|Ensembl=ENSMODG00000025357.2|UniProtKB=A0A5F8HI70 A0A5F8HI70 TMEM187 PTHR15066:SF0 TRANSMEMBRANE PROTEIN 187 TRANSMEMBRANE PROTEIN 187 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;transport vesicle#GO:0030133;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 MONDO|Ensembl=ENSMODG00000004742.3|UniProtKB=A0A5F8G7V5 A0A5F8G7V5 COPS3 PTHR10758:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3 COP9 SIGNALOSOME COMPLEX SUBUNIT 3 catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513 protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000037048.1|UniProtKB=A0A5F8HDZ8 A0A5F8HDZ8 PTHR13025:SF5 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN-CONTAINING PROTEIN D1 molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000009869.4|UniProtKB=F6VUR3 F6VUR3 REC114 PTHR34921:SF1 MEIOTIC RECOMBINATION PROTEIN REC114 MEIOTIC RECOMBINATION PROTEIN REC114 MONDO|Ensembl=ENSMODG00000000089.4|UniProtKB=F6Q8U6 F6Q8U6 ELF2 PTHR11849:SF10 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-2 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 MONDO|Ensembl=ENSMODG00000025591.3|UniProtKB=F6U275 F6U275 PTHR16213:SF78 SELENOPROTEIN N SELENOPROTEIN N skeletal muscle tissue development#GO:0007519;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;tissue development#GO:0009888;developmental process#GO:0032502;monoatomic cation homeostasis#GO:0055080;regulation of monoatomic cation transmembrane transport#GO:1904062;cellular developmental process#GO:0048869;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;regulation of transmembrane transport#GO:0034762;homeostatic process#GO:0042592;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;monoatomic ion homeostasis#GO:0050801;striated muscle tissue development#GO:0014706;chemical homeostasis#GO:0048878;muscle organ development#GO:0007517;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of release of sequestered calcium ion into cytosol#GO:0051279;striated muscle cell differentiation#GO:0051146;animal organ development#GO:0048513;regulation of biological process#GO:0050789;cell development#GO:0048468;cell differentiation#GO:0030154;inorganic ion homeostasis#GO:0098771;skeletal muscle organ development#GO:0060538;calcium ion homeostasis#GO:0055074;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000020596.4|UniProtKB=F7A086 F7A086 GABRG1 PTHR18945:SF93 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-1 ligand-gated channel activity#GO:0022834;neurotransmitter receptor activity#GO:0030594;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;channel activity#GO:0015267 nervous system development#GO:0007399;monoatomic anion transmembrane transport#GO:0098656;cellular component assembly#GO:0022607;cellular process#GO:0009987;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;chloride transport#GO:0006821;signaling#GO:0023052;synapse assembly#GO:0007416;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;animal gross anatomical part developmental process#GO:0160108;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;localization#GO:0051179;chloride transmembrane transport#GO:1902476;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537 cell projection membrane#GO:0031253;dendritic tree#GO:0097447;leading edge membrane#GO:0031256;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;cell junction#GO:0030054;signaling receptor complex#GO:0043235;neuron projection membrane#GO:0032589;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000017778.4|UniProtKB=F7DJC5 F7DJC5 SNIP1 PTHR23308:SF36 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 SMAD NUCLEAR-INTERACTING PROTEIN 1 molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 MONDO|Gene=PLB1|UniProtKB=Q06HQ7 Q06HQ7 PLB1 PTHR21325:SF52 PHOSPHOLIPASE B, PLB1 PHOSPHOLIPASE B1, MEMBRANE-ASSOCIATED A2-type glycerophospholipase activity#GO:0004623;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622 cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644 cell projection membrane#GO:0031253;cluster of actin-based cell projections#GO:0098862;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;brush border membrane#GO:0031526;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;apical plasma membrane#GO:0016324;brush border#GO:0005903;cell periphery#GO:0071944 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000009860.5|UniProtKB=F6VVA8 F6VVA8 CCDC22 PTHR15668:SF5 JM1 PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 22 protein binding#GO:0005515;binding#GO:0005488 endocytic recycling#GO:0032456;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;cellular localization#GO:0051641;regulation of intracellular signal transduction#GO:1902531;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;positive regulation of macromolecule metabolic process#GO:0010604;vesicle-mediated transport#GO:0016192;regulation of protein metabolic process#GO:0051246;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;endosomal transport#GO:0016197;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;localization#GO:0051179;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;localization within membrane#GO:0051668;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;establishment of localization#GO:0051234;positive regulation of catabolic process#GO:0009896;vesicle-mediated transport to the plasma membrane#GO:0098876;regulation of catabolic process#GO:0009894;intracellular transport#GO:0046907;transport#GO:0006810;regulation of response to stimulus#GO:0048583 MONDO|Ensembl=ENSMODG00000006946.4|UniProtKB=F6YWN3 F6YWN3 BUB1 PTHR14030:SF4 MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 MITOTIC CHECKPOINT SERINE_THREONINE-PROTEIN KINASE BUB1 catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 negative regulation of cell cycle phase transition#GO:1901988;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of chromosome separation#GO:1905818;regulation of cell cycle process#GO:0010564;negative regulation of chromosome segregation#GO:0051985;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;regulation of chromosome segregation#GO:0051983;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;meiotic sister chromatid cohesion#GO:0051177;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;negative regulation of chromosome organization#GO:2001251;sister chromatid cohesion#GO:0007062;cell communication#GO:0007154;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;biological regulation#GO:0065007;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;regulation of mitotic sister chromatid separation#GO:0010965;chromosome organization#GO:0051276;regulation of mitotic nuclear division#GO:0007088;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819 condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000001026.4|UniProtKB=F6ZF96 F6ZF96 TNFAIP8L1 PTHR12757:SF2 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8-LIKE PROTEIN 1 regulation of TOR signaling#GO:0032006;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000029662.2|UniProtKB=K7E2B3 K7E2B3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000020299.4|UniProtKB=F7BFI5 F7BFI5 C7 PTHR45742:SF2 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C7 humoral immune response#GO:0006959;positive regulation of immune response#GO:0050778;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;complement activation#GO:0006956;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;immune response#GO:0006955;immune system process#GO:0002376;regulation of immune response#GO:0050776;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;extracellular region#GO:0005576 complement component#PC00078 MONDO|Ensembl=ENSMODG00000015877.4|UniProtKB=F7B438 F7B438 PTHR13814:SF3 FETUIN HISTIDINE-RICH GLYCOPROTEIN heparin binding#GO:0008201;enzyme inhibitor activity#GO:0004857;zinc ion binding#GO:0008270;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;transition metal ion binding#GO:0046914;peptidase regulator activity#GO:0061134;small molecule binding#GO:0036094;ion binding#GO:0043167;endopeptidase regulator activity#GO:0061135;glycosaminoglycan binding#GO:0005539;cation binding#GO:0043169;carbohydrate derivative binding#GO:0097367;binding#GO:0005488;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872 response to biotic stimulus#GO:0009607;regulation of response to wounding#GO:1903034;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;regulation of multicellular organismal process#GO:0051239;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;positive regulation of response to external stimulus#GO:0032103;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;response to stimulus#GO:0050896;regulation of blood coagulation#GO:0030193;regulation of body fluid levels#GO:0050878;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of wound healing#GO:0061041;immune system process#GO:0002376;positive regulation of coagulation#GO:0050820;regulation of biological quality#GO:0065008;immune response#GO:0006955;regulation of hemostasis#GO:1900046;positive regulation of response to stimulus#GO:0048584;regulation of coagulation#GO:0050818;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;defense response#GO:0006952;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;regulation of platelet activation#GO:0010543;regulation of immune response#GO:0050776;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000037775.1|UniProtKB=A0A5F8GRJ3 A0A5F8GRJ3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000029671.2|UniProtKB=K7E5Y7 K7E5Y7 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009598.4|UniProtKB=F7A8R4 F7A8R4 HOXD4 PTHR45771:SF5 HOMEOTIC PROTEIN DEFORMED HOMEOBOX PROTEIN HOX-D4 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;positive regulation of RNA metabolic process#GO:0051254;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;skeletal system morphogenesis#GO:0048705;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of metabolic process#GO:0009893;skeletal system development#GO:0001501;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;anterior/posterior pattern specification#GO:0009952;positive regulation of macromolecule metabolic process#GO:0010604;embryo development#GO:0009790;positive regulation of biological process#GO:0048518 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000014909.3|UniProtKB=F7G656 F7G656 HSD17B1 PTHR43391:SF15 RETINOL DEHYDROGENASE-RELATED 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 estrogen metabolic process#GO:0008210;steroid biosynthetic process#GO:0006694;regulation of biological quality#GO:0065008;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;hormone metabolic process#GO:0042445;lipid biosynthetic process#GO:0008610;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;biological regulation#GO:0065007;hormone biosynthetic process#GO:0042446;primary metabolic process#GO:0044238;cellular process#GO:0009987;regulation of hormone levels#GO:0010817 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 MONDO|Ensembl=ENSMODG00000012979.4|UniProtKB=F6WJL6 F6WJL6 GSDMA PTHR16399:SF18 GASDERMIN GASDERMIN-A transporter#PC00227 MONDO|Ensembl=ENSMODG00000028495.2|UniProtKB=K7E0N1 K7E0N1 PTHR15657:SF1 THYROID TRANSCRIPTION FACTOR 1-ASSOCIATED PROTEIN 26 THYROID TRANSCRIPTION FACTOR 1-ASSOCIATED PROTEIN 26 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000050076.1|UniProtKB=A0A5F8H9U0 A0A5F8H9U0 PTHR13372:SF2 GEMININ GEMININ COILED-COIL DOMAIN-CONTAINING PROTEIN 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA replication#GO:0006275;biological regulation#GO:0065007;regulation of DNA-templated DNA replication initiation#GO:0030174;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000037961.1|UniProtKB=A0A5F8GPG9 A0A5F8GPG9 EFCAB3 PTHR47500:SF2 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 3 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000029187.2|UniProtKB=K7E1A6 K7E1A6 PTHR46077:SF3 E3 UBIQUITIN-PROTEIN LIGASE TOPORS RING-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000019344.3|UniProtKB=H9H7B5 H9H7B5 LOC100028941 PTHR48002:SF127 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4Q2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048892.1|UniProtKB=A0A5F8GB32 A0A5F8GB32 PTHR31253:SF0 BRI3-BINDING PROTEIN BRI3-BINDING PROTEIN membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000009182.3|UniProtKB=F7ACZ5 F7ACZ5 PTHR24103:SF700 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM7 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000040647.1|UniProtKB=A0A5F8GXC6 A0A5F8GXC6 PTHR10127:SF855 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING ASTACIN-LIKE METALLOENDOPEPTIDASE endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cell activation#GO:0001775;sexual reproduction#GO:0019953;single fertilization#GO:0007338;negative regulation of biological process#GO:0048519;cellular process#GO:0009987;regulation of biological process#GO:0050789;multicellular organismal process#GO:0032501;regulation of reproductive process#GO:2000241;fertilization#GO:0009566;reproductive process#GO:0022414;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000002309.5|UniProtKB=F6YDQ7 F6YDQ7 ARPP21 PTHR15672:SF14 CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN CAMP-REGULATED PHOSPHOPROTEIN 21 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000014793.3|UniProtKB=F7E6H4 F7E6H4 RAB5A PTHR47978:SF69 FAMILY NOT NAMED SMALL MONOMERIC GTPASE hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000019205.5|UniProtKB=F6ZIS3 F6ZIS3 G3BP2 PTHR10693:SF10 RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;molecular condensate scaffold activity#GO:0140693 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular component assembly#GO:0022607;cytoplasmic stress granule assembly#GO:0034063 cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000047379.1|UniProtKB=A0A5F8H0G4 A0A5F8H0G4 TOMM22 PTHR12504:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 HOMOLOG establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585 mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial outer membrane translocase complex#GO:0005742;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000001390.4|UniProtKB=A0A5F8G8M2 A0A5F8G8M2 FER PTHR24418:SF227 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FER transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;binding#GO:0005488;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular process#GO:0009987;taxis#GO:0042330;response to chemical#GO:0042221;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;signaling#GO:0023052;locomotion#GO:0040011;chemotaxis#GO:0006935;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of immune response#GO:0050776;cell adhesion#GO:0007155;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 Cadherin signaling pathway#P00012>Fer#P00469 MONDO|Ensembl=ENSMODG00000017816.3|UniProtKB=F6ZXQ3 F6ZXQ3 TUBGCP4 PTHR19302:SF27 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 4 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spindle assembly#GO:0051225;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000040958.1|UniProtKB=K7E411 K7E411 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000013170.3|UniProtKB=F6ZLP9 F6ZLP9 PTHR13527:SF0 SAYSVFN DOMAIN-CONTAINING PROTEIN 1 SAYSVFN DOMAIN-CONTAINING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 rescue of stalled cytosolic ribosome#GO:0072344;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cytoplasmic translation#GO:0002181;catabolic process#GO:0009056;protein biosynthetic process#GO:0160307;protein catabolic process#GO:0030163;translation#GO:0006412;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;translational elongation#GO:0006414;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000020654.5|UniProtKB=F7E5Y1 F7E5Y1 FIP1L1 PTHR13484:SF9 FIP1-LIKE 1 PROTEIN PRE-MRNA 3'-END-PROCESSING FACTOR FIP1 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152 mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000016247.4|UniProtKB=F7C2B7 F7C2B7 SULF2 PTHR43108:SF4 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER EXTRACELLULAR SULFATASE SULF-2 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;carbohydrate derivative catabolic process#GO:1901136;protein metabolic process#GO:0019538;positive regulation of biosynthetic process#GO:0009891;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;carbohydrate derivative metabolic process#GO:1901135;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;negative regulation of biological process#GO:0048519;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;positive regulation of signaling#GO:0023056;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968;regulation of multicellular organismal process#GO:0051239;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;proteoglycan metabolic process#GO:0006029 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000023218.4|UniProtKB=F7BI06 F7BI06 GJA8 PTHR11984:SF19 CONNEXIN GAP JUNCTION ALPHA-8 PROTEIN passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267 establishment of localization#GO:0051234;cell communication#GO:0007154;localization#GO:0051179;transport#GO:0006810;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cellular process#GO:0009987;regulation of biological process#GO:0050789 cell junction#GO:0030054;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 gap junction#PC00105;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000001079.4|UniProtKB=F7GHZ3 F7GHZ3 SMURF1 PTHR11254:SF293 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE SMURF1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;regulation of BMP signaling pathway#GO:0030510;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;negative regulation of BMP signaling pathway#GO:0030514;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490;TGF-beta signaling pathway#P00052>Smurfs#P01279 MONDO|Ensembl=ENSMODG00000001662.4|UniProtKB=A0A5F8HEG8 A0A5F8HEG8 NFASC PTHR10075:SF113 BASIGIN RELATED NEUROFASCIN cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000001216.2|UniProtKB=A0A5F8G343 A0A5F8G343 PTHR28342:SF1 MONOOXYGENASE P33MONOX-RELATED MONOOXYGENASE P33MONOX-RELATED intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000004045.4|UniProtKB=F7CLS6 F7CLS6 CACNG1 PTHR15025:SF1 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246;transporter regulator activity#GO:0141108 regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of transmembrane transport#GO:0034762;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924 calcium channel complex#GO:0034704;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;sarcolemma#GO:0042383;transporter complex#GO:1990351 transporter#PC00227;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000024659.3|UniProtKB=F7CA76 F7CA76 PTHR11918:SF45 RADICAL SAM PROTEINS THREONYLCARBAMOYLADENOSINE TRNA METHYLTHIOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on RNA#GO:0140098 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000045468.1|UniProtKB=A0A5F8HF26 A0A5F8HF26 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008431.2|UniProtKB=F7AL10 F7AL10 MED7 PTHR15498:SF72 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN CONTAINING TIM MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000018909.5|UniProtKB=F7C782 F7C782 ENPP4 PTHR10151:SF79 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE BIS(5'-ADENOSYL)-TRIPHOSPHATASE ENPP4 hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000025523.3|UniProtKB=F6V2F4 F6V2F4 PTHR15907:SF4 DUF614 FAMILY PROTEIN-RELATED PLACENTA ASSOCIATED 8, TANDEM DUPLICATE 2-RELATED positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355 MONDO|Ensembl=ENSMODG00000047383.1|UniProtKB=A0A5F8H9F6 A0A5F8H9F6 FUNDC1 PTHR21346:SF2 FUN14 DOMAIN CONTAINING FUN14 DOMAIN-CONTAINING PROTEIN 1 process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056;autophagy#GO:0006914;cellular process#GO:0009987;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 MONDO|Ensembl=ENSMODG00000036761.1|UniProtKB=F7E0N4 F7E0N4 LOC100020485 PTHR48018:SF28 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8K3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005259.3|UniProtKB=F7GGX0 F7GGX0 TEKT5 PTHR19960:SF23 TEKTIN TEKTIN-5 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030 microtubule cytoskeleton#GO:0015630;motile cilium#GO:0031514;organelle#GO:0043226;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoskeleton#GO:0005856;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000012240.3|UniProtKB=F6Z6B8 F6Z6B8 RHPN2 PTHR23031:SF5 RHOPHILIN RHOPHILIN-2-RELATED regulation of actin filament organization#GO:0110053;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of actin filament bundle assembly#GO:0032231;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;negative regulation of cytoskeleton organization#GO:0051494 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017847.4|UniProtKB=F6Z8B1 F6Z8B1 EPB42 PTHR11590:SF44 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN 4.2 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 transferase#PC00220 MONDO|Ensembl=ENSMODG00000002373.3|UniProtKB=F7G381 F7G381 CPE PTHR11532:SF92 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE E catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190 Vasopressin synthesis#P04395>Exopeptidase#P04592;CCKR signaling map#P06959>Carboxypeptidase E#P07026 MONDO|Ensembl=ENSMODG00000010473.2|UniProtKB=F7ET20 F7ET20 MOB1A PTHR22599:SF30 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 1A enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;hippo signaling#GO:0035329;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase activator#PC00138 CCKR signaling map#P06959>MOB1#G07283;CCKR signaling map#P06959>MOB1#G06990 MONDO|Ensembl=ENSMODG00000027963.2|UniProtKB=F6ZXF2 F6ZXF2 PTHR24376:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 850 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000007497.4|UniProtKB=A0A5F8G362 A0A5F8G362 ACTN2 PTHR11915:SF429 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-2 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;muscle cell differentiation#GO:0042692;cellular component organization#GO:0016043;muscle cell development#GO:0055001;cell development#GO:0048468;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;membrane#GO:0016020;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;cell periphery#GO:0071944;cell junction#GO:0030054;sarcomere#GO:0030017;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;I band#GO:0031674;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 MONDO|Ensembl=ENSMODG00000017353.4|UniProtKB=F6WEV0 F6WEV0 PTHR47115:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 183 COILED-COIL DOMAIN-CONTAINING PROTEIN 183 MONDO|Ensembl=ENSMODG00000028984.2|UniProtKB=K7E3T0 K7E3T0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007894.4|UniProtKB=F6YT84 F6YT84 PARP4 PTHR46530:SF1 PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP4 PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP4 catalytic activity#GO:0003824;transferase activity#GO:0016740;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 FAS signaling pathway#P00020>PARP#P00600 MONDO|Ensembl=ENSMODG00000018491.2|UniProtKB=F7BRP5 F7BRP5 NDUFB11 PTHR13327:SF0 NADH-UBIQUINONE OXIDOREDUCTASE ESSS SUBUNIT, MITOCHONDRIAL PRECURSOR NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 11, MITOCHONDRIAL transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000004135.4|UniProtKB=F6UDX2 F6UDX2 CHEK1 PTHR24343:SF540 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE CHK1 catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;histone modifying activity#GO:0140993;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;cellular response to stress#GO:0033554;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000013825.5|UniProtKB=A0A5F8GCJ7 A0A5F8GCJ7 BUD13 PTHR31809:SF0 BUD13 HOMOLOG BUD13 HOMOLOG primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000008595.4|UniProtKB=F6PHC4 F6PHC4 BTN2A2 PTHR24100:SF156 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 2 MEMBER A2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;immune system process#GO:0002376;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000047785.1|UniProtKB=A0A5F8HKT7 A0A5F8HKT7 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000011480.4|UniProtKB=F6VJG1 F6VJG1 AMMECR1 PTHR13016:SF2 AMMECR1 HOMOLOG NUCLEAR PROTEIN AMMECR1 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000002981.4|UniProtKB=F6Q4V3 F6Q4V3 NEK1 PTHR44899:SF4 CAMK FAMILY PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE NEK1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000003598.3|UniProtKB=F7FBF4 F7FBF4 DNAAF10 PTHR10971:SF2 MRNA EXPORT FACTOR AND BUB3 DYNEIN AXONEMAL ASSEMBLY FACTOR 10 binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000004143.4|UniProtKB=F6RAA4 F6RAA4 TCF3 PTHR11793:SF7 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR E2-ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000041045.1|UniProtKB=F7E8I0 F7E8I0 LOC100019112 PTHR26450:SF7 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012223.4|UniProtKB=F6Z6T6 F6Z6T6 BRD8 PTHR15398:SF4 BROMODOMAIN-CONTAINING PROTEIN 8 BROMODOMAIN-CONTAINING PROTEIN 8 MONDO|Ensembl=ENSMODG00000024915.1|UniProtKB=F6SGB2 F6SGB2 HDAC8 PTHR10625:SF14 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 8 catalytic activity#GO:0003824;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;protein-containing complex#GO:0032991 Wnt signaling pathway#P00057>Histone deacetylase#P01472 MONDO|Ensembl=ENSMODG00000005780.4|UniProtKB=F6XY15 F6XY15 THBS2 PTHR10199:SF10 THROMBOSPONDIN THROMBOSPONDIN-2 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 regulation of angiogenesis#GO:0045765;negative regulation of angiogenesis#GO:0016525;regulation of anatomical structure morphogenesis#GO:0022603;regulation of vasculature development#GO:1901342;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of multicellular organismal process#GO:0051239;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000004570.5|UniProtKB=A0A5F8HKF9 A0A5F8HKF9 PTHR13900:SF0 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1 binding#GO:0005488;transcription factor binding#GO:0008134;protein binding#GO:0005515 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123 RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000018776.4|UniProtKB=F7ADM5 F7ADM5 CA14 PTHR18952:SF84 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 14 hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000005778.3|UniProtKB=F6XY67 F6XY67 PTHR19367:SF52 T-CELL RECEPTOR ALPHA CHAIN V REGION IG-LIKE DOMAIN-CONTAINING PROTEIN adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000005819.4|UniProtKB=F7AR07 F7AR07 CNGA2 PTHR45638:SF3 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL ALPHA-2 purine ribonucleotide binding#GO:0032555;monoatomic ion channel activity#GO:0005216;heterocyclic compound binding#GO:1901363;monoatomic ion transmembrane transporter activity#GO:0015075;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;monoatomic cation transmembrane transporter activity#GO:0008324;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;gated channel activity#GO:0022836;guanyl nucleotide binding#GO:0019001;monoatomic cation channel activity#GO:0005261;nucleotide binding#GO:0000166;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;channel activity#GO:0015267;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;ligand-gated monoatomic ion channel activity#GO:0015276 monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;system process#GO:0003008;monoatomic ion transport#GO:0006811;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;transport#GO:0006810;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 ion channel#PC00133;ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000025190.2|UniProtKB=F7D1M3 F7D1M3 PTHR23187:SF3 FLJ44216 PROTEIN-RELATED SUMO-INTERACTING MOTIF-CONTAINING PROTEIN 1 peptidase inhibitor activity#GO:0030414;enzyme inhibitor activity#GO:0004857;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605 MONDO|Ensembl=ENSMODG00000029692.2|UniProtKB=K7E3B5 K7E3B5 LOC103105715 PTHR11849:SF170 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-4 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 MONDO|Ensembl=ENSMODG00000006653.4|UniProtKB=F7G3Z0 F7G3Z0 ELAVL3 PTHR10352:SF15 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 3 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000021515.4|UniProtKB=F7FSF7 F7FSF7 CHST9 PTHR12137:SF6 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 9 transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 transferase#PC00220 MONDO|Ensembl=ENSMODG00000037189.1|UniProtKB=A0A5F8GII9 A0A5F8GII9 PTHR10666:SF424 UBIQUITIN UBIQUITIN-RIBOSOMAL PROTEIN EL40 FUSION PROTEIN structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;nucleus#GO:0005634;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000018738.3|UniProtKB=F7EFL7 F7EFL7 ACP6 PTHR11567:SF202 ACID PHOSPHATASE-RELATED LYSOPHOSPHATIDIC ACID PHOSPHATASE TYPE 6 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000006260.4|UniProtKB=F7FE16 F7FE16 ASGR1 PTHR22802:SF470 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR 1 binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000008635.3|UniProtKB=F6PGL5 F6PGL5 B9D2 PTHR12968:SF2 B9 DOMAIN-CONTAINING B9 DOMAIN-CONTAINING PROTEIN 2 cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 ciliary transition zone#GO:0035869;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000012566.4|UniProtKB=F6PLA6 F6PLA6 SOCS7 PTHR10155:SF5 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 7 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;response to hormone#GO:0009725;cell surface receptor signaling pathway#GO:0007166;cellular response to insulin stimulus#GO:0032869;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to chemical stimulus#GO:0070887 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 MONDO|Ensembl=ENSMODG00000011556.4|UniProtKB=F6QCH4 F6QCH4 TBC1D2B PTHR22957:SF621 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 2B enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000017978.4|UniProtKB=F7BUT0 F7BUT0 CD164 PTHR11337:SF12 MUCIN/PORIMIN SIALOMUCIN CORE PROTEIN 24 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 MONDO|Ensembl=ENSMODG00000006970.3|UniProtKB=K7E0T9 K7E0T9 ELOC PTHR20648:SF13 ELONGIN-C ELONGIN-C protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000044768.1|UniProtKB=A0A5F8H113 A0A5F8H113 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000045377.1|UniProtKB=K7E0P2 K7E0P2 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000023955.1|UniProtKB=F6ZFY5 F6ZFY5 LOC100617313 PTHR22847:SF751 WD40 REPEAT PROTEIN WD REPEAT DOMAIN 5B chromatin-protein adaptor activity#GO:0140463;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566 gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;transcription initiation at RNA polymerase II promoter#GO:0006367;transcription initiation-coupled chromatin remodeling#GO:0045815;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;chromatin remodeling#GO:0006338;DNA-templated transcription initiation#GO:0006352;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;nucleic acid biosynthetic process#GO:0141187;chromatin organization#GO:0006325;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891 intracellular organelle lumen#GO:0070013;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;NSL complex#GO:0044545;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;chromosome#GO:0005694;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;membraneless organelle#GO:0043228;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000015360.4|UniProtKB=F6WXH7 F6WXH7 RFC5 PTHR11669:SF9 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 5 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;replication fork#GO:0005657;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 MONDO|Ensembl=ENSMODG00000000712.4|UniProtKB=F6WL75 F6WL75 MMP1 PTHR10201:SF151 MATRIX METALLOPROTEINASE INTERSTITIAL COLLAGENASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;cellular component organization#GO:0016043 metalloprotease#PC00153 Plasminogen activating cascade#P00050>MMP-1#P01252;Plasminogen activating cascade#P00050>pro-MMP-1#P01263;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 MONDO|Ensembl=ENSMODG00000037285.1|UniProtKB=F7C289 F7C289 LOC100616680 PTHR26453:SF26 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024520.2|UniProtKB=F7AK03 F7AK03 LOC100028403 PTHR48002:SF99 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005926.4|UniProtKB=F6WWS7 F6WWS7 TYMP PTHR10515:SF0 THYMIDINE PHOSPHORYLASE THYMIDINE PHOSPHORYLASE pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 glycosyltransferase#PC00111 Salvage pyrimidine deoxyribonucleotides#P02774>Uracil phosphorylase#P03145;Pyrimidine Metabolism#P02771>Nucleoside Phosphorylase#P03126;Salvage pyrimidine deoxyribonucleotides#P02774>Thymidine phosphorylase#P03148 MONDO|Ensembl=ENSMODG00000007428.4|UniProtKB=F7EDX2 F7EDX2 MRPL18 PTHR12899:SF23 39S RIBOSOMAL PROTEIN L18, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL18M RNA binding#GO:0003723;rRNA binding#GO:0019843;binding#GO:0005488;nucleic acid binding#GO:0003676 establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;nucleic acid transport#GO:0050657;localization#GO:0051179;transport#GO:0006810 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000028850.2|UniProtKB=K7DZL5 K7DZL5 PTHR22382:SF7 RIKEN CDNA 4921504E06 GENE RIKEN CDNA 4921504E06 GENE MONDO|Ensembl=ENSMODG00000027457.2|UniProtKB=K7E188 K7E188 PTHR37360:SF1 FRAGILE X MENTAL RETARDATION 1 NEIGHBOR PROTEIN FMR1 NEIGHBOR PROTEIN MONDO|Ensembl=ENSMODG00000042805.1|UniProtKB=A0A5F8HI85 A0A5F8HI85 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000008815.3|UniProtKB=F6QA79 F6QA79 CIMAP1C PTHR21580:SF3 SHIPPO-1-RELATED CILIARY MICROTUBULE ASSOCIATED PROTEIN 1C developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell development#GO:0048468;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;spermatid differentiation#GO:0048515;sexual reproduction#GO:0019953;spermatid development#GO:0007286;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;cellular process#GO:0009987;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869 cytoplasmic microtubule#GO:0005881;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000010922.2|UniProtKB=F7F505 F7F505 ZFTRAF1 PTHR23059:SF4 CYSTEINE AND HISTIDINE-RICH PROTEIN 1 ZINC FINGER TRAF-TYPE-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000000151.4|UniProtKB=A0A5F8GYB0 A0A5F8GYB0 PTHR15874:SF1 NUCLEOLAR AND SPINDLE-ASSOCIATED PROTEIN 1 NUCLEOLAR AND SPINDLE-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 cytokinesis#GO:0000910;nuclear division#GO:0000280;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;spindle localization#GO:0051653;cellular localization#GO:0051641;cytoskeleton-dependent cytokinesis#GO:0061640;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;establishment of organelle localization#GO:0051656;chromosome segregation#GO:0007059;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;organelle localization#GO:0051640;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;localization#GO:0051179;cell division#GO:0051301;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;establishment of localization#GO:0051234;establishment of spindle localization#GO:0051293;mitotic sister chromatid segregation#GO:0000070 mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;spindle#GO:0005819;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000048256.1|UniProtKB=A0A5F8HBX3 A0A5F8HBX3 PTHR10105:SF3 SELENOPROTEIN P SELENOPROTEIN P cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000038882.1|UniProtKB=A0A5F8GTT4 A0A5F8GTT4 RPL22L1 PTHR10064:SF1 60S RIBOSOMAL PROTEIN L22 RIBOSOMAL PROTEIN EL22-LIKE nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;RNA binding#GO:0003723;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000014241.4|UniProtKB=A0A5F8HM29 A0A5F8HM29 LOC100013930 PTHR23239:SF97 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA1 structural molecule activity#GO:0005198 organelle organization#GO:0006996;cellular process#GO:0009987;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435 supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000008880.3|UniProtKB=F7CAA2 F7CAA2 PRICKLE1 PTHR24211:SF15 LIM DOMAIN-CONTAINING PROTEIN PRICKLE-LIKE PROTEIN 1 protein localization to organelle#GO:0033365;cell motility#GO:0048870;tube morphogenesis#GO:0035239;establishment of cell polarity#GO:0030010;nuclear transport#GO:0051169;system development#GO:0048731;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;localization#GO:0051179;embryo development ending in birth or egg hatching#GO:0009792;nucleocytoplasmic transport#GO:0006913;plasma membrane bounded cell projection organization#GO:0120036;tube development#GO:0035295;multicellular organismal process#GO:0032501;cell migration#GO:0016477;tissue development#GO:0009888;epithelium development#GO:0060429;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;neurogenesis#GO:0022008;intracellular protein localization#GO:0008104;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;developmental process#GO:0032502;intracellular transport#GO:0046907;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neuron development#GO:0048666;protein import into nucleus#GO:0006606;protein transport#GO:0015031;cellular localization#GO:0051641;generation of neurons#GO:0048699;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;nervous system development#GO:0007399;embryo development#GO:0009790;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;neuron projection development#GO:0031175;anatomical structure formation involved in morphogenesis#GO:0048646;morphogenesis of an epithelium#GO:0002009;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;neuron differentiation#GO:0030182 postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;cell junction#GO:0030054;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;postsynapse#GO:0098794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017213.4|UniProtKB=A0A5F8HDJ0 A0A5F8HDJ0 TUBB4B PTHR11588:SF247 TUBULIN TUBULIN BETA-4B CHAIN heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874 tubulin#PC00228;cytoskeletal protein#PC00085 Huntington disease#P00029>Microtubule#P00780;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>beta-Tubulin#P00790 MONDO|Ensembl=ENSMODG00000000449.4|UniProtKB=F6USK5 F6USK5 HOXA13 PTHR45804:SF3 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-A13 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000018633.4|UniProtKB=F7B2L4 F7B2L4 FAM168B PTHR31844:SF2 MYELIN-ASSOCIATED NEURITE-OUTGROWTH INHIBITOR-RELATED MYELIN-ASSOCIATED NEURITE-OUTGROWTH INHIBITOR myelin protein#PC00161;structural protein#PC00211 MONDO|Ensembl=ENSMODG00000043634.1|UniProtKB=A0A5F8H098 A0A5F8H098 GIMAP6 PTHR10903:SF144 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 6 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000002587.4|UniProtKB=A0A5F8GVY1 A0A5F8GVY1 DGLUCY PTHR32022:SF10 D-GLUTAMATE CYCLASE, MITOCHONDRIAL D-GLUTAMATE CYCLASE, MITOCHONDRIAL catalytic activity#GO:0003824;cyclase activity#GO:0009975;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 cyclase#PC00079;lyase#PC00144 MONDO|Ensembl=ENSMODG00000028349.2|UniProtKB=K7E2P3 K7E2P3 PTHR22748:SF23 AP ENDONUCLEASE EXODEOXYRIBONUCLEASE III catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;DNA exonuclease activity#GO:0004529;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;DNA endonuclease activity#GO:0004520;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;response to stress#GO:0006950;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000008182.4|UniProtKB=F7E4W2 F7E4W2 HMCES PTHR13604:SF1 DC12-RELATED ABASIC SITE PROCESSING PROTEIN HMCES lyase activity#GO:0016829;DNA binding#GO:0003677;damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824 production of molecular mediator of immune response#GO:0002440;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;somatic diversification of immune receptors#GO:0002200;cellular response to stimulus#GO:0051716;immune system development#GO:0002520;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;cellular response to stress#GO:0033554;gene expression#GO:0010467;multicellular organismal process#GO:0032501;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;interstrand cross-link repair#GO:0036297;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;double-strand break repair via nonhomologous end joining#GO:0006303;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;developmental process#GO:0032502 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;replication fork#GO:0005657;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000000206.4|UniProtKB=F7E9N1 F7E9N1 RIT2 PTHR24070:SF203 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN RIT2 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;protein binding#GO:0005515 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;positive regulation of neuron projection development#GO:0010976;Ras protein signal transduction#GO:0007265;positive regulation of cell projection organization#GO:0031346;positive regulation of cellular component organization#GO:0051130;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000013901.2|UniProtKB=A0A5F8H8H9 A0A5F8H8H9 PTHR13768:SF2 SOLUBLE NSF ATTACHMENT PROTEIN SNAP GAMMA-SOLUBLE NSF ATTACHMENT PROTEIN membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000006832.3|UniProtKB=F6PG42 F6PG42 PTHR13486:SF2 TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER SPLICING FACTOR C9ORF78 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000028759.2|UniProtKB=K7DZT6 K7DZT6 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000008200.4|UniProtKB=F7DJ69 F7DJ69 PTHR46613:SF1 RADIAL SPOKE HEAD 10 HOMOLOG B-RELATED RADIAL SPOKE HEAD 10 HOMOLOG B-RELATED MONDO|Ensembl=ENSMODG00000018720.4|UniProtKB=F7FC02 F7FC02 RAB23 PTHR24073:SF209 DRAB5-RELATED RAS-RELATED PROTEIN RAB-23 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 macroautophagy#GO:0016236;cellular component assembly#GO:0022607;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;catabolic process#GO:0009056;cellular component organization#GO:0016043;vacuole organization#GO:0007033;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;cellular localization#GO:0051641;organelle assembly#GO:0070925 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000007811.4|UniProtKB=F7ETW2 F7ETW2 PTCHD1 PTHR10796:SF36 PATCHED-RELATED PATCHED DOMAIN-CONTAINING PROTEIN 1 nervous system process#GO:0050877;cognition#GO:0050890;system process#GO:0003008;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000018318.4|UniProtKB=F6PTL6 F6PTL6 PTHR14453:SF89 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP14 transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;transferase activity#GO:0016740;transcription coregulator activity#GO:0003712;glycosyltransferase activity#GO:0016757;transcription regulator activity#GO:0140110;pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950 negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of cytokine-mediated signaling pathway#GO:0001959;negative regulation of cytokine-mediated signaling pathway#GO:0001960;negative regulation of signal transduction#GO:0009968;negative regulation of innate immune response#GO:0045824;negative regulation of response to external stimulus#GO:0032102;regulation of response to external stimulus#GO:0032101;regulation of response to cytokine stimulus#GO:0060759;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;negative regulation of immune response#GO:0050777;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;negative regulation of response to cytokine stimulus#GO:0060761;negative regulation of defense response#GO:0031348;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;negative regulation of response to stimulus#GO:0048585;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000006696.4|UniProtKB=F7DH53 F7DH53 GP2 PTHR14002:SF16 ENDOGLIN/TGF-BETA RECEPTOR TYPE III PANCREATIC SECRETORY GRANULE MEMBRANE MAJOR GLYCOPROTEIN GP2 myeloid leukocyte migration#GO:0097529;leukocyte migration#GO:0050900;immune system process#GO:0002376;neutrophil migration#GO:1990266;cell migration#GO:0016477;granulocyte migration#GO:0097530;cell motility#GO:0048870;cellular process#GO:0009987 apical part of cell#GO:0045177;extracellular region#GO:0005576;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025764.2|UniProtKB=F7G3D7 F7G3D7 ACP1 PTHR11717:SF34 LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000009938.4|UniProtKB=F7D7Y9 F7D7Y9 CPD PTHR11532:SF73 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 MONDO|Ensembl=ENSMODG00000003337.4|UniProtKB=F7DCI6 F7DCI6 IPO4 PTHR10527:SF6 IMPORTIN BETA IMPORTIN-4 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;localization#GO:0051179;cellular localization#GO:0051641;protein localization to organelle#GO:0033365;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 MONDO|Ensembl=ENSMODG00000019865.4|UniProtKB=F6RR64 F6RR64 PTHR43795:SF17 BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE-LIKE PROTEIN 1 catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-sulfur lyase activity#GO:0016846 metabolite interconversion enzyme#PC00262;transferase#PC00220;transaminase#PC00216 MONDO|Ensembl=ENSMODG00000028644.2|UniProtKB=K7E3D8 K7E3D8 PTHR31635:SF196 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED MONDO|Ensembl=ENSMODG00000041890.1|UniProtKB=A0A5F8H0Y8 A0A5F8H0Y8 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000023917.2|UniProtKB=A0A5F8HIH4 A0A5F8HIH4 SOCS4 PTHR10155:SF21 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 4 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 MONDO|Ensembl=ENSMODG00000007710.5|UniProtKB=F7EVE8 F7EVE8 TUT1 PTHR12271:SF127 POLY A POLYMERASE CID PAP -RELATED SPECKLE TARGETED PIP5K1A-REGULATED POLY(A) POLYMERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098 regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;modification-dependent macromolecule catabolic process#GO:0043632;RNA catabolic process#GO:0006401;positive regulation of macromolecule metabolic process#GO:0010604;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;metabolic process#GO:0008152 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;membraneless organelle#GO:0043228;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 nucleotidyltransferase#PC00174 MONDO|Ensembl=ENSMODG00000047111.1|UniProtKB=K7E1V0 K7E1V0 PTHR25952:SF256 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000021142.4|UniProtKB=A0A5F8GTV0 A0A5F8GTV0 PTHR31915:SF8 SKICH DOMAIN-CONTAINING PROTEIN TAX1-BINDING PROTEIN 1 regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519 MONDO|Ensembl=ENSMODG00000001516.5|UniProtKB=F7F481 F7F481 ZBTB49 PTHR24399:SF72 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 49 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000051601.1|UniProtKB=F6WE63 F6WE63 LOC100030159 PTHR26453:SF119 OLFACTORY RECEPTOR ODORANT RECEPTOR M34 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011534.3|UniProtKB=F6QXU7 F6QXU7 NUDT16 PTHR31699:SF5 NUDIX T16 FAMILY MEMBER U8 SNORNA-DECAPPING ENZYME nucleic acid binding#GO:0003676;binding#GO:0005488;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nuclease activity#GO:0004518;snoRNA binding#GO:0030515;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519 RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000002097.2|UniProtKB=F6UHB0 F6UHB0 IL10 PTHR48482:SF5 INTERLEUKIN-19-RELATED INTERLEUKIN-10 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;negative regulation of defense response#GO:0031348;positive regulation of cell communication#GO:0010647;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;negative regulation of biological process#GO:0048519;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;immune system process#GO:0002376;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;negative regulation of response to external stimulus#GO:0032102;regulation of response to external stimulus#GO:0032101;response to chemical#GO:0042221;response to cytokine#GO:0034097;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Interleukin signaling pathway#P00036>Interleukin#P00970 MONDO|Ensembl=ENSMODG00000019379.3|UniProtKB=F6WSH8 F6WSH8 HDGFL3 PTHR12550:SF84 HEPATOMA-DERIVED GROWTH FACTOR-RELATED HEPATOMA-DERIVED GROWTH FACTOR-RELATED PROTEIN 3 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000004671.3|UniProtKB=F6U739 F6U739 PLEKHJ1 PTHR22902:SF9 SESQUIPEDALIAN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY J MEMBER 1 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000004803.4|UniProtKB=A0A5F8GS53 A0A5F8GS53 BROX PTHR23032:SF13 BRO1 DOMAIN-CONTAINING PROTEIN BROX BRO1 DOMAIN-CONTAINING PROTEIN BROX MONDO|Ensembl=ENSMODG00000019604.4|UniProtKB=F6Y7H9 F6Y7H9 ASTN2 PTHR16592:SF2 ASTROTACTIN-1-LIKE ASTROTACTIN-2 ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;alcohol binding#GO:0043178 cell differentiation#GO:0030154;cell motility#GO:0048870;cell adhesion#GO:0007155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell migration#GO:0016477;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000000728.4|UniProtKB=F6W5Y9 F6W5Y9 GSDME PTHR15207:SF1 NONSYNDROMIC HEARING IMPAIRMENT PROTEIN GASDERMIN-E transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 programmed cell death#GO:0012501;response to stress#GO:0006950;cell death#GO:0008219;cellular process#GO:0009987;inflammatory response#GO:0006954;response to stimulus#GO:0050896;defense response#GO:0006952 membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000012990.4|UniProtKB=F7CS46 F7CS46 CRTAM PTHR47118:SF1 CYTOTOXIC AND REGULATORY T-CELL MOLECULE CYTOTOXIC AND REGULATORY T-CELL MOLECULE protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of immune response#GO:0050776;cell recognition#GO:0008037;regulation of defense response#GO:0031347;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;regulation of leukocyte mediated immunity#GO:0002703;regulation of natural killer cell mediated immunity#GO:0002715;regulation of response to biotic stimulus#GO:0002831;positive regulation of natural killer cell mediated immunity#GO:0002717;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stress#GO:0080134;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;detection of stimulus#GO:0051606;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;regulation of natural killer cell mediated cytotoxicity#GO:0042269;positive regulation of response to stimulus#GO:0048584;regulation of cell killing#GO:0031341;regulation of lymphocyte mediated immunity#GO:0002706;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of response to external stimulus#GO:0032103;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;regulation of response to external stimulus#GO:0032101 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000038328.1|UniProtKB=A0A5F8HC48 A0A5F8HC48 COLEC11 PTHR24024:SF14 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A COLLECTIN-11 pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;humoral immune response#GO:0006959;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;defense response to other organism#GO:0098542;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;immune response#GO:0006955;complement activation#GO:0006956;immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211;surfactant#PC00212 MONDO|Ensembl=ENSMODG00000006027.4|UniProtKB=F7AII6 F7AII6 PTHR12755:SF3 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9 phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740 cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146;RNA processing factor#PC00147;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000010840.3|UniProtKB=F7BDC7 F7BDC7 PTHR10489:SF627 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 8 cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;chemotaxis#GO:0006935;cell communication#GO:0007154;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000016874.5|UniProtKB=F6RUJ9 F6RUJ9 ADGB PTHR46298:SF1 ANDROGLOBIN ANDROGLOBIN membrane-bounded organelle#GO:0043227;cilium#GO:0005929;9+2 motile cilium#GO:0097729;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000024749.2|UniProtKB=F6YYI5 F6YYI5 HYI PTHR43489:SF6 ISOMERASE HYDROXYPYRUVATE ISOMERASE-RELATED intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;glyoxylate metabolic process#GO:0046487;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 isomerase#PC00135;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000009856.4|UniProtKB=F6WA79 F6WA79 YWHAH PTHR18860:SF16 14-3-3 PROTEIN 14-3-3 PROTEIN ETA scaffold/adaptor protein#PC00226 FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539;Parkinson disease#P00049>14-3-3#P01238 MONDO|Ensembl=ENSMODG00000017263.4|UniProtKB=F6T4D9 F6T4D9 ADAT2 PTHR11079:SF208 CYTOSINE DEAMINASE FAMILY MEMBER TRNA-SPECIFIC ADENOSINE-34 DEAMINASE CATALYTIC SUBUNIT ADAT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;adenosine deaminase activity#GO:0004000;tRNA-specific adenosine deaminase activity#GO:0008251 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;adenosine to inosine editing#GO:0006382;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;base conversion or substitution editing#GO:0016553 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;deaminase#PC00088 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCTP deaminase#P02920;Salvage pyrimidine ribonucleotides#P02775>Cytosine deaminase#P03155;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144;Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154 MONDO|Ensembl=ENSMODG00000050946.1|UniProtKB=A0A5F8GE32 A0A5F8GE32 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000020455.4|UniProtKB=A0A5F8GKD6 A0A5F8GKD6 TCF4 PTHR11793:SF10 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR 4 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785 basic helix-loop-helix transcription factor#PC00055 CCKR signaling map#P06959>TCF7L2#P07126 MONDO|Ensembl=ENSMODG00000018286.4|UniProtKB=F6PWT5 F6PWT5 FBXO40 PTHR15933:SF1 PROTEIN CBG16327 F-BOX ONLY PROTEIN 40 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000007215.4|UniProtKB=F6WSN6 F6WSN6 TRPA1 PTHR24123:SF124 ANKYRIN REPEAT-CONTAINING TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY A MEMBER 1 monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;sensory perception of pain#GO:0019233;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;metal ion transport#GO:0030001;sensory perception of chemical stimulus#GO:0007606;transport#GO:0006810;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;system process#GO:0003008;calcium ion transport#GO:0006816;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;cellular process#GO:0009987;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000002836.3|UniProtKB=F6YVE6 F6YVE6 PTHR34441:SF2 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000016919.4|UniProtKB=A0A5F8G7E9 A0A5F8G7E9 FAM107B PTHR16768:SF1 DOWN REGULATED IN RENAL CARCINOMA 1/TU3A PROTEIN FAM107B MONDO|Ensembl=ENSMODG00000042749.1|UniProtKB=A0A5F8H2Q4 A0A5F8H2Q4 PTHR16675:SF67 MHC CLASS I-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000007443.4|UniProtKB=F7DW67 F7DW67 ZXDC PTHR46179:SF5 ZINC FINGER PROTEIN ZINC FINGER PROTEIN ZXDC transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000000382.4|UniProtKB=F6R8S5 F6R8S5 PTHR31767:SF0 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-LIKE SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-LIKE SUBUNIT voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000016533.5|UniProtKB=F7E855 F7E855 SRRM2 PTHR34755:SF3 SERINE/ARGININE REPETITIVE MATRIX PROTEIN 3-RELATED SERINE_ARGININE REPETITIVE MATRIX PROTEIN 2 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 MONDO|Ensembl=ENSMODG00000029720.2|UniProtKB=A0A5F8H6D2 A0A5F8H6D2 PTHR15299:SF3 HERV-H LTR-ASSOCIATING PROTEIN 1 HERV-H LTR-ASSOCIATING PROTEIN 1 MONDO|Ensembl=ENSMODG00000019114.4|UniProtKB=F6TJI5 F6TJI5 LOC100017328 PTHR12015:SF103 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 4-LIKE signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488 signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;response to peptide#GO:1901652;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;taxis#GO:0042330;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;response to stress#GO:0006950;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;cell surface receptor signaling pathway#GO:0007166;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell chemotaxis#GO:0060326;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;regulation of cell motility#GO:2000145;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cytokine-mediated signaling pathway#GO:0019221;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;cell migration#GO:0016477;positive regulation of cell migration#GO:0030335;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;positive regulation of locomotion#GO:0040017;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;regulation of cell migration#GO:0030334;leukocyte migration#GO:0050900 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000044713.1|UniProtKB=A0A5F8HC33 A0A5F8HC33 LOC100011747 PTHR19306:SF6 STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;damaged DNA binding#GO:0003684 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;site of double-strand break#GO:0035861;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000010539.3|UniProtKB=F6ZF01 F6ZF01 PTHR10989:SF17 ANDROGEN-INDUCED PROTEIN 1-RELATED ANDROGEN-DEPENDENT TFPI-REGULATING PROTEIN hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;long-chain fatty acid metabolic process#GO:0001676;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane raft#GO:0045121;membrane#GO:0016020;caveola#GO:0005901;cell periphery#GO:0071944;plasma membrane raft#GO:0044853;membrane microdomain#GO:0098857 MONDO|Ensembl=ENSMODG00000019420.3|UniProtKB=F6SYG0 F6SYG0 RAD17 PTHR12172:SF5 CELL CYCLE CHECKPOINT PROTEIN RAD17 CELL CYCLE CHECKPOINT PROTEIN RAD17 chromatin-protein adaptor activity#GO:0140463;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;negative regulation of cell cycle#GO:0045786;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle G2/M phase transition#GO:1902750;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cell cycle process#GO:0010564;cellular response to stress#GO:0033554;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;mitotic DNA replication checkpoint signaling#GO:0033314;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;mitotic G2/M transition checkpoint#GO:0044818;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;DNA damage checkpoint signaling#GO:0000077;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;intracellular signal transduction#GO:0035556;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794 site of double-strand break#GO:0035861;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromosome, telomeric region#GO:0000781;membraneless organelle#GO:0043228;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;site of DNA damage#GO:0090734;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000005902.3|UniProtKB=F6XD64 F6XD64 PTHR11599:SF40 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-7 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;nucleus#GO:0005634 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 MONDO|Ensembl=ENSMODG00000003469.5|UniProtKB=A0A5F8GUL4 A0A5F8GUL4 DOK7 PTHR21636:SF2 PROTEIN DOK-7 PROTEIN DOK-7 protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization#GO:0016043;neuromuscular junction development#GO:0007528;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 MONDO|Ensembl=ENSMODG00000011928.3|UniProtKB=F7DZB0 F7DZB0 FBXO22 PTHR14939:SF10 F-BOX ONLY PROTEIN 22 F-BOX ONLY PROTEIN 22 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;regulation of cell differentiation#GO:0045595;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;regulation of cell development#GO:0060284;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000014586.3|UniProtKB=F7A4Y3 F7A4Y3 RNF144A PTHR11685:SF99 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF144A catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056 intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;Golgi apparatus#GO:0005794;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000011922.4|UniProtKB=F7DZH8 F7DZH8 SFXN3 PTHR11153:SF20 SIDEROFLEXIN SIDEROFLEXIN-3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;intracellular transport#GO:0046907;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;amino acid transmembrane transport#GO:0003333;cellular localization#GO:0051641;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000014121.5|UniProtKB=F6Y3U0 F6Y3U0 PHF1 PTHR12628:SF11 POLYCOMB-LIKE TRANSCRIPTION FACTOR PHD FINGER PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;DNA binding#GO:0003677 negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000049877.1|UniProtKB=A0A5F8GTW2 A0A5F8GTW2 FAM98C PTHR31353:SF10 FAM98 PROTEIN FAM98C catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000014366.4|UniProtKB=F6TP80 F6TP80 PSMB8 PTHR11599:SF53 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-8 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;proteasome complex#GO:0000502 protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000018798.4|UniProtKB=F6ZN00 F6ZN00 KLHL31 PTHR45632:SF17 LD33804P KELCH-LIKE PROTEIN 31 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 negative regulation of intracellular signal transduction#GO:1902532;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of JNK cascade#GO:0046328;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of response to stimulus#GO:0048585;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000025679.2|UniProtKB=F6U0P9 F6U0P9 PTHR23419:SF1 DIVALENT CATION TOLERANCE CUTA-RELATED PROTEIN CUTA metal ion binding#GO:0046872;cation binding#GO:0043169;copper ion binding#GO:0005507;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000000085.4|UniProtKB=F6Q953 F6Q953 TBX20 PTHR11267:SF210 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX20 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 morphogenesis of an epithelium#GO:0002009;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;animal organ development#GO:0048513;left/right pattern formation#GO:0060972;cell fate specification#GO:0001708;determination of bilateral symmetry#GO:0009855;embryo development#GO:0009790;heart development#GO:0007507;cellular process#GO:0009987;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;specification of symmetry#GO:0009799;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;tube development#GO:0035295;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;tissue development#GO:0009888;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;tissue morphogenesis#GO:0048729;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;embryonic organ development#GO:0048568;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;heart morphogenesis#GO:0003007;determination of left/right symmetry#GO:0007368;tube morphogenesis#GO:0035239 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 MONDO|Ensembl=ENSMODG00000016092.5|UniProtKB=F7A531 F7A531 ZBTB40 PTHR24394:SF0 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 40 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000008788.4|UniProtKB=F6RFE9 F6RFE9 HMBOX1 PTHR14618:SF0 HOMEODOX-CONTAINING PROTEIN 1 HMBOX1 HOMEOBOX-CONTAINING PROTEIN 1 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000040563.1|UniProtKB=F7FSK6 F7FSK6 PTHR26453:SF69 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000011.4|UniProtKB=F6SJ04 F6SJ04 PCDH9 PTHR24028:SF248 CADHERIN-87A PROTOCADHERIN-9 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000011446.2|UniProtKB=F6W1H4 F6W1H4 NDUFA2 PTHR12878:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B8 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 2 respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000010206.3|UniProtKB=F6SAV3 F6SAV3 OR6N1 PTHR26453:SF697 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6N1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019195.4|UniProtKB=A0A5F8GJW7 A0A5F8GJW7 PARM1 PTHR35453:SF1 PROSTATE ANDROGEN-REGULATED MUCIN-LIKE PROTEIN 1 PROSTATE ANDROGEN-REGULATED MUCIN-LIKE PROTEIN 1 membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;Golgi apparatus#GO:0005794;late endosome#GO:0005770;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000014237.3|UniProtKB=F6T934 F6T934 SLC16A7 PTHR11360:SF25 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 2 monocarboxylic acid transmembrane transporter activity#GO:0008028;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 carboxylic acid transmembrane transport#GO:1905039;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810 membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000001045.4|UniProtKB=F7DPN1 F7DPN1 ZNF608 PTHR21564:SF4 BRAKELESS PROTEIN ZINC FINGER PROTEIN 608 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000005040.4|UniProtKB=A0A5F8GAT0 A0A5F8GAT0 APLP2 PTHR23103:SF14 ALZHEIMER'S DISEASE BETA-AMYLOID RELATED AMYLOID BETA PRECURSOR LIKE PROTEIN 2 axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;central nervous system development#GO:0007417;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000009974.4|UniProtKB=F6Y7T9 F6Y7T9 CCDC169 PTHR28671:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 169 COILED-COIL DOMAIN-CONTAINING PROTEIN 169 MONDO|Ensembl=ENSMODG00000000482.4|UniProtKB=A0A5F8GTM6 A0A5F8GTM6 NEGR1 PTHR42757:SF6 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED NEURONAL GROWTH REGULATOR 1 regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803;cell adhesion#GO:0007155;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;regulation of synapse assembly#GO:0051963;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell-cell adhesion#GO:0098609 postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;plasma membrane#GO:0005886;postsynaptic density#GO:0014069;cell junction#GO:0030054 immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000025209.2|UniProtKB=F7BFL6 F7BFL6 PTHR11387:SF12 CYTOCHROME C OXIDASE SUBUNIT 6B CYTOCHROME C OXIDASE SUBUNIT 6B2 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidase#PC00175;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000018882.5|UniProtKB=A0A5F8G938 A0A5F8G938 ADGRF5 PTHR45813:SF13 IG-LIKE DOMAIN-CONTAINING PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR F5 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;carbohydrate homeostasis#GO:0033500;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;homeostatic process#GO:0042592;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;energy reserve metabolic process#GO:0006112;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;chemical homeostasis#GO:0048878;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;multicellular organismal-level homeostasis#GO:0048871;glucose homeostasis#GO:0042593 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000002222.3|UniProtKB=F7DFZ7 F7DFZ7 SGSH PTHR43108:SF6 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER N-SULPHOGLUCOSAMINE SULPHOHYDROLASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;proteoglycan metabolic process#GO:0006029;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;aminoglycan metabolic process#GO:0006022;glycosaminoglycan catabolic process#GO:0006027;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;glycosaminoglycan metabolic process#GO:0030203;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000037933.1|UniProtKB=A0A5F8G604 A0A5F8G604 LOC103103531 PTHR46507:SF5 AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN-LIKE localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;intraciliary transport involved in cilium assembly#GO:0035735;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;centriolar satellite#GO:0034451;cell projection#GO:0042995;membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000037649.1|UniProtKB=A0A5F8H3T2 A0A5F8H3T2 PTHR24379:SF134 KRAB AND ZINC FINGER DOMAIN-CONTAINING RIKEN CDNA 2610008E11 GENE LIKE-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000017388.4|UniProtKB=F6SL62 F6SL62 HPCA PTHR23055:SF57 CALCIUM BINDING PROTEINS NEURON-SPECIFIC CALCIUM-BINDING PROTEIN HIPPOCALCIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000050973.1|UniProtKB=F6PP39 F6PP39 VN2R514 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000008644.4|UniProtKB=F6PGG4 F6PGG4 PLPP4 PTHR10165:SF90 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 4 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;dephosphorylation#GO:0016311;lipid modification#GO:0030258;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000006442.4|UniProtKB=F7EGK4 F7EGK4 PTHR21463:SF0 ANGIOPOIETIN-LIKE PROTEIN 8 ANGIOPOIETIN-LIKE PROTEIN 8 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179 triglyceride homeostasis#GO:0070328;regulation of lipid metabolic process#GO:0019216;chemical homeostasis#GO:0048878;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;lipid homeostasis#GO:0055088;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000002932.4|UniProtKB=A0A5F8H334 A0A5F8H334 TBC1D14 PTHR22957:SF367 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 14 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 regulation of autophagosome assembly#GO:2000785;regulation of organelle organization#GO:0033043;regulation of organelle assembly#GO:1902115;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128 intracellular organelle#GO:0043229;endosome#GO:0005768;recycling endosome#GO:0055037;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000013808.3|UniProtKB=F6SY64 F6SY64 PTHR10078:SF27 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-1 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;inflammatory response#GO:0006954;cytokine-mediated signaling pathway#GO:0019221;response to bacterium#GO:0009617;cell communication#GO:0007154;immune response#GO:0006955;response to other organism#GO:0051707;biological regulation#GO:0065007;defense response#GO:0006952;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;cellular response to cytokine stimulus#GO:0071345;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to peptide#GO:1901652;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;cytokine#PC00083;interleukin superfamily#PC00128 MONDO|Ensembl=ENSMODG00000013171.3|UniProtKB=F6ZLN6 F6ZLN6 TRIM29 PTHR25465:SF7 B-BOX DOMAIN CONTAINING TRIPARTITE MOTIF-CONTAINING PROTEIN 29 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000008459.4|UniProtKB=F7GET9 F7GET9 PTHR23171:SF19 GDOWN1 DNA-DIRECTED RNA POLYMERASE II SUBUNIT GRINL1A transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle#GO:0043226;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000010034.4|UniProtKB=F6TUG9 F6TUG9 MINDY3 PTHR12473:SF17 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-3 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;catalytic activity#GO:0003824 MONDO|Ensembl=ENSMODG00000045075.1|UniProtKB=A0A5F8GQA7 A0A5F8GQA7 PTHR24411:SF8 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 MONDO|Ensembl=ENSMODG00000013027.3|UniProtKB=F7BNL9 F7BNL9 LOC103093609 PTHR36960:SF1 SI:DKEY-32E6.3 HMG BOX DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000001098.3|UniProtKB=F7DPM7 F7DPM7 MSH2 PTHR11361:SF156 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH2 catalytic activity, acting on DNA#GO:0140097;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657 immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;immune system development#GO:0002520;lymphocyte mediated immunity#GO:0002449;cellular response to stress#GO:0033554;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;response to stimulus#GO:0050896;production of molecular mediator of immune response#GO:0002440;mismatch repair#GO:0006298;multicellular organism development#GO:0007275;DNA recombination#GO:0006310;immune effector process#GO:0002252;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;gene expression#GO:0010467;somatic recombination of immunoglobulin gene segments#GO:0016447;cellular process#GO:0009987;response to stress#GO:0006950;system development#GO:0048731;anatomical structure development#GO:0048856;mitotic recombination#GO:0006312;cellular response to stimulus#GO:0051716;somatic diversification of immune receptors#GO:0002200;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;developmental process#GO:0032502;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;somatic cell DNA recombination#GO:0016444;adaptive immune response#GO:0002250;multicellular organismal process#GO:0032501;immune response#GO:0006955;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000008918.6|UniProtKB=F7FJ26 F7FJ26 ACTA1 PTHR11937:SF193 ACTIN ACTIN, ALPHA SKELETAL MUSCLE structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;actin filament organization#GO:0007015;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cell differentiation#GO:0030154;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle cell development#GO:0055001;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;actomyosin#GO:0042641;sarcomere#GO:0030017;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;stress fiber#GO:0001725;cytoskeleton#GO:0005856;actin filament#GO:0005884;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;myofibril#GO:0030016;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858 MONDO|Ensembl=ENSMODG00000045206.1|UniProtKB=A0A5F8GPY5 A0A5F8GPY5 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000007196.3|UniProtKB=F6X936 F6X936 POLD3 PTHR17598:SF13 DNA POLYMERASE DELTA SUBUNIT 3 DNA POLYMERASE DELTA SUBUNIT 3 DNA-directed DNA polymerase activity#GO:0003887;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097 response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;response to radiation#GO:0009314;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular response to light stimulus#GO:0071482;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;biosynthetic process#GO:0009058;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;response to UV#GO:0009411;macromolecule metabolic process#GO:0043170;cellular response to abiotic stimulus#GO:0071214;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to environmental stimulus#GO:0104004;cellular response to radiation#GO:0071478;DNA strand elongation involved in DNA replication#GO:0006271;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA-templated DNA replication#GO:0006261 protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;replisome#GO:0030894;replication fork#GO:0005657;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000029681.2|UniProtKB=A0A5F8GNG4 A0A5F8GNG4 PTHR12560:SF6 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 ceramide metabolic process#GO:0006672;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000018276.4|UniProtKB=F6PW70 F6PW70 RAD51AP1 PTHR15361:SF4 RAD51/NUKS-INTERACTING PROTEIN RAD51-ASSOCIATED PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 MONDO|Ensembl=ENSMODG00000039866.1|UniProtKB=A0A5F8HH19 A0A5F8HH19 VN2R607 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012888.4|UniProtKB=F6Z1C3 F6Z1C3 PTHR23267:SF176 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 8-61 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000037126.1|UniProtKB=A0A5F8HH70 A0A5F8HH70 LOC100028464 PTHR26452:SF977 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000045362.1|UniProtKB=A0A5F8GMW3 A0A5F8GMW3 LOC130459037 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000408.4|UniProtKB=F6QMH1 F6QMH1 STEAP3 PTHR14239:SF8 DUDULIN-RELATED METALLOREDUCTASE STEAP3 oxidoreductase activity, acting on metal ions#GO:0016722;oxidoreductase activity#GO:0016491;ferric-chelate reductase activity#GO:0000293;catalytic activity#GO:0003824 transition metal ion transport#GO:0000041;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811 vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 reductase#PC00198 MONDO|Ensembl=ENSMODG00000014994.4|UniProtKB=A0A5F8G408 A0A5F8G408 F2RL3 PTHR24232:SF22 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 4 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Blood coagulation#P00011>PAR-4#P00461 MONDO|Ensembl=ENSMODG00000016594.3|UniProtKB=H9H5Y7 H9H5Y7 PTHR24247:SF205 5-HYDROXYTRYPTAMINE RECEPTOR D(4) DOPAMINE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594 anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537 plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Dopamine receptor mediated signaling pathway#P05912>D2/D3/D4#P05965;Nicotine pharmacodynamics pathway#P06587>DRD2/ DRD3/ DRD4#P06603;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 MONDO|Ensembl=ENSMODG00000019380.4|UniProtKB=A0A5F8GRI0 A0A5F8GRI0 BNC1 PTHR15021:SF1 DISCONNECTED-RELATED ZINC FINGER PROTEIN BASONUCLIN-1 regulation of transcription by RNA polymerase I#GO:0006356;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000012989.4|UniProtKB=F7CS51 F7CS51 PSMD3 PTHR10758:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056 endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;proteasome complex#GO:0000502;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000019488.4|UniProtKB=F6WA06 F6WA06 UNC45A PTHR45994:SF3 FI21225P1 PROTEIN UNC-45 HOMOLOG A Hsp90 protein binding#GO:0051879;heat shock protein binding#GO:0031072;binding#GO:0005488;protein binding#GO:0005515 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000045947.1|UniProtKB=A0A5F8GJ95 A0A5F8GJ95 LOC100022653 PTHR11426:SF228 HISTONE H3 HISTONE H3.3 chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;kinetochore assembly#GO:0051382;organelle localization#GO:0051640;nuclear division#GO:0000280;organelle assembly#GO:0070925;organelle fission#GO:0048285;localization#GO:0051179;kinetochore organization#GO:0051383;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 MONDO|Ensembl=ENSMODG00000014810.4|UniProtKB=F7DLQ8 F7DLQ8 COIL PTHR15197:SF0 COILIN P80 COILIN RNA binding#GO:0003723;snRNA binding#GO:0017069;nucleic acid binding#GO:0003676;binding#GO:0005488 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;spliceosomal snRNP assembly#GO:0000387;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000006830.4|UniProtKB=F6PG53 F6PG53 SLC39A2 PTHR11040:SF120 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP2 monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000008896.3|UniProtKB=F7BRF9 F7BRF9 SOX7 PTHR10270:SF210 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-7 sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067 cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000002355.3|UniProtKB=F7GDV9 F7GDV9 AKR1A1 PTHR11732:SF385 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER A1 alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000008271.5|UniProtKB=F6Z838 F6Z838 SLC6A8 PTHR11616:SF96 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT CREATINE TRANSPORTER 1 amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283 amino acid transport#GO:0006865;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 MONDO|Ensembl=ENSMODG00000003060.4|UniProtKB=A0A5F8GUU0 A0A5F8GUU0 TTC8 PTHR44177:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 8 TETRATRICOPEPTIDE REPEAT PROTEIN 8 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229;BBSome#GO:0034464;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815 MONDO|Ensembl=ENSMODG00000015225.4|UniProtKB=F6V2Z8 F6V2Z8 GLDC PTHR11773:SF1 GLYCINE DEHYDROGENASE, DECARBOXYLATING GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000016765.4|UniProtKB=F7GGC9 F7GGC9 MTHFD1L PTHR48099:SF12 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED MONOFUNCTIONAL C1-TETRAHYDROFOLATE SYNTHASE, MITOCHONDRIAL hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 tetrahydrofolate metabolic process#GO:0046653;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;tetrahydrofolate biosynthetic process#GO:0046654;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;biosynthetic process#GO:0009058;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 MONDO|Ensembl=ENSMODG00000018516.4|UniProtKB=F7AGR4 F7AGR4 FBH1 PTHR11070:SF30 UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER F-BOX DNA HELICASE 1 catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;DNA helicase activity#GO:0003678;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;cellular process#GO:0009987;response to stress#GO:0006950;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000050453.1|UniProtKB=A0A5F8GBA7 A0A5F8GBA7 STIMATE PTHR31735:SF2 VACUOLAR MEMBRANE PROTEIN YPL162C STORE-OPERATED CALCIUM ENTRY REGULATOR STIMATE transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 endoplasmic reticulum#GO:0005783;endoplasmic reticulum tubular network#GO:0071782;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;cortical endoplasmic reticulum#GO:0032541;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000043601.1|UniProtKB=A0A5F8GZ88 A0A5F8GZ88 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000008907.3|UniProtKB=F7B486 F7B486 FAM110B PTHR14758:SF2 AGAP005440-PA PROTEIN FAM110B MONDO|Ensembl=ENSMODG00000004958.4|UniProtKB=F7FX68 F7FX68 NFRKB PTHR13052:SF3 NFRKB-RELATED NUCLEAR FACTOR RELATED TO KAPPA-B-BINDING PROTEIN enzyme binding#GO:0019899;protease binding#GO:0002020;binding#GO:0005488;protein binding#GO:0005515 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000003499.3|UniProtKB=F7CRY4 F7CRY4 UBA52 PTHR10666:SF437 UBIQUITIN POLYUBIQUITIN-B structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000018889.4|UniProtKB=F7CR83 F7CR83 TDRD6 PTHR22948:SF15 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 6 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000015775.4|UniProtKB=F6Z4G4 F6Z4G4 SLC33A1 PTHR12778:SF9 SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED ACETYL-COENZYME A TRANSPORTER 1 organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000010665.4|UniProtKB=F7CKF6 F7CKF6 FAM171B PTHR31626:SF2 SUSHI DOMAIN-CONTAINING PROTEIN PROTEIN FAM171B MONDO|Ensembl=ENSMODG00000020887.4|UniProtKB=H9H7P9 H9H7P9 ALDH4A1 PTHR14516:SF3 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FAMILY MEMBER DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 MONDO|Ensembl=ENSMODG00000021477.4|UniProtKB=F7G374 F7G374 LOC100020341 PTHR24418:SF90 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE YES non-membrane spanning protein tyrosine kinase activity#GO:0004715;binding#GO:0005488;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular developmental process#GO:0048869;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 Cadherin signaling pathway#P00012>Yes#P00476;Parkinson disease#P00049>Src kinase#P01230;CCKR signaling map#P06959>YES1#P07142 MONDO|Ensembl=ENSMODG00000011832.3|UniProtKB=K7E131 K7E131 NAGS PTHR23342:SF22 N-ACETYLGLUTAMATE SYNTHASE N-ACETYLGLUTAMATE SYNTHASE, MITOCHONDRIAL acyltransferase activity#GO:0016746;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;L-arginine biosynthetic process#GO:0006526;proteinogenic amino acid biosynthetic process#GO:0170038 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Arginine biosynthesis#P02728>N-acetylglutamate synthase#P02848 MONDO|Ensembl=ENSMODG00000016589.4|UniProtKB=H9H703 H9H703 XRCC6 PTHR12604:SF2 KU AUTOANTIGEN DNA HELICASE DNA REPAIR PROTEIN KU70 DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;telomeric repeat DNA binding#GO:0042162;nucleic acid binding#GO:0003676;binding#GO:0005488 DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;double-strand break repair#GO:0006302;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;telomere organization#GO:0032200;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA helicase#PC00011 MONDO|Ensembl=ENSMODG00000015221.5|UniProtKB=F6V3U1 F6V3U1 GCN1 PTHR23346:SF7 TRANSLATIONAL ACTIVATOR GCN1-RELATED STALLED RIBOSOME SENSOR GCN1 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 cellular response to starvation#GO:0009267;post-transcriptional regulation of gene expression#GO:0010608;cellular response to nutrient levels#GO:0031669;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of translation#GO:0006417;response to nutrient levels#GO:0031667;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;cellular response to amino acid starvation#GO:0034198;biological regulation#GO:0065007;cellular response to stress#GO:0033554;response to starvation#GO:0042594;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000023472.3|UniProtKB=F6SR48 F6SR48 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000003779.4|UniProtKB=F7AAC6 F7AAC6 PTHR22545:SF0 CENTROSOMAL PROTEIN OF 95 KDA CENTROSOMAL PROTEIN OF 95 KDA intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819 MONDO|Ensembl=ENSMODG00000007483.4|UniProtKB=A0A5F8G866 A0A5F8G866 C8orf34 PTHR32000:SF3 SIMILAR TO HYPOTHETICAL PROTEIN SIMILAR TO HUMAN CHROMOSOME 8 OPEN READING FRAME 34 MONDO|Ensembl=ENSMODG00000018389.4|UniProtKB=F6QUC0 F6QUC0 IQCG PTHR14871:SF1 DYNEIN REGULATORY COMPLEX PROTEIN 9 DYNEIN REGULATORY COMPLEX PROTEIN 9 sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;9+2 motile cilium#GO:0097729;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000000861.3|UniProtKB=F7BHR0 F7BHR0 LAP3 PTHR11963:SF23 LEUCINE AMINOPEPTIDASE-RELATED CYTOSOL AMINOPEPTIDASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000003220.4|UniProtKB=F6TYV3 F6TYV3 LRRC45 PTHR23170:SF3 NY-REN-58 ANTIGEN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 45 MONDO|Ensembl=ENSMODG00000046141.1|UniProtKB=A0A5F8GLG0 A0A5F8GLG0 LOC100028534 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000023717.2|UniProtKB=F6VEI2 F6VEI2 FNDC9 PTHR37361:SF2 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 9 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 9 MONDO|Ensembl=ENSMODG00000009799.2|UniProtKB=F6SYX1 F6SYX1 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000000318.4|UniProtKB=H9H9M3 H9H9M3 PTHR24027:SF425 CADHERIN-23 CADHERIN-23 beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell migration#GO:0016477 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000016688.4|UniProtKB=F7DMC4 F7DMC4 PIGQ PTHR21329:SF3 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q-RELATED PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;organophosphate metabolic process#GO:0019637;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;phospholipid metabolic process#GO:0006644 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000023383.3|UniProtKB=A0A5F8GU15 A0A5F8GU15 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000043092.1|UniProtKB=A0A5F8H5P2 A0A5F8H5P2 STMN2 PTHR10104:SF18 STATHMIN STATHMIN-2 protein binding#GO:0005515;binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 regulation of microtubule-based process#GO:0032886;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;system development#GO:0048731;supramolecular fiber organization#GO:0097435;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;protein-containing complex disassembly#GO:0032984;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule polymerization or depolymerization#GO:0031109;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;protein depolymerization#GO:0051261;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cellular component disassembly#GO:0022411;neuron development#GO:0048666;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell development#GO:0048468;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule depolymerization#GO:0007019;regulation of microtubule cytoskeleton organization#GO:0070507;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010 growth cone#GO:0030426;axon#GO:0030424;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;distal axon#GO:0150034;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000048345.1|UniProtKB=A0A5F8GRX2 A0A5F8GRX2 C4orf54 PTHR33775:SF4 CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN-RELATED SIMILAR TO HUMAN CHROMOSOME 4 OPEN READING FRAME 54 MONDO|Ensembl=ENSMODG00000010705.3|UniProtKB=F7GH71 F7GH71 PLPP5 PTHR10165:SF87 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 5 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644 membrane#GO:0016020;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000019063.3|UniProtKB=H9H794 H9H794 POLR2F PTHR47227:SF5 DNA-DIRECTED RNA POLYMERASE SUBUNIT K DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2 catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription by RNA polymerase I#GO:0006360 RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880 DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 MONDO|Ensembl=ENSMODG00000047698.1|UniProtKB=F7DG50 F7DG50 LOC100022551 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048013.1|UniProtKB=F7ANK6 F7ANK6 PTHR26450:SF42 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048219.1|UniProtKB=A0A5F8H3S3 A0A5F8H3S3 MOB3C PTHR22599:SF12 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 3C kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000012362.5|UniProtKB=F7B3D3 F7B3D3 PRDM2 PTHR16515:SF37 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 2-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000039089.1|UniProtKB=A0A5F8G1T1 A0A5F8G1T1 PTHR13250:SF1 TF-1 CELL APOPTOSIS RELATED PROTEIN-15 PROGRAMMED CELL DEATH PROTEIN 10 protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;protein binding#GO:0005515 cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000005439.4|UniProtKB=F7D0J8 F7D0J8 LOC100023204 PTHR24300:SF400 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C9 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;tetrapyrrole binding#GO:0046906;binding#GO:0005488 cellular response to xenobiotic stimulus#GO:0071466;icosanoid metabolic process#GO:0006690;response to chemical#GO:0042221;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;olefinic compound metabolic process#GO:0120254;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000013926.3|UniProtKB=F6SUZ7 F6SUZ7 LOC100022567 PTHR10701:SF24 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN N binding#GO:0005488;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;cytoplasm#GO:0005737;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;U2 snRNP#GO:0005686;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;spliceosomal complex#GO:0005681;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;U2-type prespliceosome#GO:0071004;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525 RNA splicing factor#PC00148 Gonadotropin-releasing hormone receptor pathway#P06664>SNURF#P06808 MONDO|Ensembl=ENSMODG00000017546.4|UniProtKB=F7E104 F7E104 NACC2 PTHR46105:SF2 AGAP004733-PA NUCLEUS ACCUMBENS-ASSOCIATED PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000050077.1|UniProtKB=A0A5F8H155 A0A5F8H155 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000038768.1|UniProtKB=A0A5F8H104 A0A5F8H104 NEK3 PTHR44984:SF1 SERINE/THREONINE-PROTEIN KINASE NEK3 SERINE_THREONINE-PROTEIN KINASE NEK3 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000012510.3|UniProtKB=F6Q0P1 F6Q0P1 PTHR26453:SF627 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037265.1|UniProtKB=M9MMJ3 M9MMJ3 PTHR44427:SF13 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 4-RELATED cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000004474.4|UniProtKB=A0A5F8G3X6 A0A5F8G3X6 PTHR44324:SF3 WD40 REPEAT DOMAIN 95 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 337 MONDO|Ensembl=ENSMODG00000002131.4|UniProtKB=F7FX36 F7FX36 POLK PTHR11076:SF33 DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER DNA POLYMERASE KAPPA catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;DNA-directed DNA polymerase activity#GO:0003887 nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA synthesis involved in DNA replication#GO:0090592;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;DNA biosynthetic process#GO:0071897;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translesion synthesis#GO:0019985 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000024593.2|UniProtKB=F6Q640 F6Q640 PTHR14256:SF3 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT CYTOCHROME C OXIDASE ASSOCIATED SUBUNIT FA4L3 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000009643.3|UniProtKB=F6QTD0 F6QTD0 EIF2AK3 PTHR11042:SF166 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 3 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of translation#GO:0017148;regulation of translational initiation#GO:0006446 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>EIF2AK3#P06813 MONDO|Ensembl=ENSMODG00000015224.4|UniProtKB=F7B7H7 F7B7H7 FSCN3 PTHR10551:SF1 FASCIN FASCIN-3 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;supramolecular fiber organization#GO:0097435;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cell migration#GO:0016477;cellular component assembly#GO:0022607;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 cell projection membrane#GO:0031253;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;filopodium#GO:0030175;growth cone#GO:0030426;axon#GO:0030424;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;membraneless organelle#GO:0043228;ruffle#GO:0001726;cytoskeleton#GO:0005856;lamellipodium#GO:0030027;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000025361.2|UniProtKB=A0A5F8HLS0 A0A5F8HLS0 TCEANC PTHR11477:SF7 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A N-TERMINAL AND CENTRAL DOMAIN-CONTAINING PROTEIN transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000025749.2|UniProtKB=A0A5F8GMG1 A0A5F8GMG1 PTHR19971:SF24 SIGNAL-REGULATORY PROTEIN BETA IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003891.2|UniProtKB=F7D8L0 F7D8L0 HEPACAM PTHR12080:SF59 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE HEPATIC AND GLIAL CELL ADHESION MOLECULE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;macromolecule localization#GO:0033036;regulation of biological process#GO:0050789;signal transduction#GO:0007165;immune response#GO:0006955;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;localization#GO:0051179;cell communication#GO:0007154;intracellular protein localization#GO:0008104;immune system process#GO:0002376;protein localization to cell junction#GO:1902414 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000050119.1|UniProtKB=A0A5F8HGE8 A0A5F8HGE8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007766.4|UniProtKB=F7AXG6 F7AXG6 LOC100026848 PTHR28658:SF1 TRANSMEMBRANE PROTEIN 180 MAJOR FACILITATOR SUPERFAMILY DOMAIN CONTAINING 13B MONDO|Ensembl=ENSMODG00000008028.3|UniProtKB=F7CKR3 F7CKR3 FAHD2A PTHR42796:SF4 FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A-RELATED OXALOACETATE TAUTOMERASE FAHD2A, MITOCHONDRIAL hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000001626.4|UniProtKB=A0A5F8G2J8 A0A5F8G2J8 RYR3 PTHR46399:SF9 B30.2/SPRY DOMAIN-CONTAINING PROTEIN RYANODINE RECEPTOR 3 channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated calcium channel activity#GO:0099604;calcium ion transmembrane transporter activity#GO:0015085;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;muscle system process#GO:0003012;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;transport#GO:0006810;muscle contraction#GO:0006936;calcium ion transport#GO:0006816;system process#GO:0003008;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;monoatomic ion transmembrane transport#GO:0034220;release of sequestered calcium ion into cytosol by sarcoplasmic reticulum#GO:0014808;monoatomic cation transmembrane transport#GO:0098655;multicellular organismal process#GO:0032501 endoplasmic reticulum membrane#GO:0005789;I band#GO:0031674;sarcolemma#GO:0042383;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;membrane#GO:0016020;cell periphery#GO:0071944;Z disc#GO:0030018;endomembrane system#GO:0012505;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;sarcoplasm#GO:0016528;endoplasmic reticulum subcompartment#GO:0098827;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cation channel complex#GO:0034703;endoplasmic reticulum#GO:0005783;sarcomere#GO:0030017;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;sarcoplasmic reticulum#GO:0016529;contractile muscle fiber#GO:0043292;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;sarcoplasmic reticulum membrane#GO:0033017;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;myofibril#GO:0030016;organelle subcompartment#GO:0031984;supramolecular fiber#GO:0099512;calcium channel complex#GO:0034704;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165 CCKR signaling map#P06959>RYR1/2/3#P07088;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441;Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434 MONDO|Ensembl=ENSMODG00000006654.4|UniProtKB=F6ZMG9 F6ZMG9 PALB2 PTHR14662:SF2 PARTNER AND LOCALIZER OF BRCA2 PARTNER AND LOCALIZER OF BRCA2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 MONDO|Ensembl=ENSMODG00000038491.1|UniProtKB=A0A5F8H931 A0A5F8H931 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000042219.1|UniProtKB=A0A5F8GIX5 A0A5F8GIX5 LOC100019309 PTHR45710:SF35 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 EARLY ACTIVATION ANTIGEN CD69 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;lymphocyte activation#GO:0046649;positive regulation of response to stimulus#GO:0048584;antigen receptor-mediated signaling pathway#GO:0050851;multicellular organismal process#GO:0032501;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;immune system process#GO:0002376;regulation of immune response#GO:0050776;cell activation#GO:0001775;cell communication#GO:0007154;leukocyte activation#GO:0045321;T cell activation#GO:0042110;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000013382.3|UniProtKB=F7DSW5 F7DSW5 S1PR3 PTHR22750:SF24 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 3 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000004407.4|UniProtKB=A0A5F8GGD9 A0A5F8GGD9 SLC7A5 PTHR11785:SF315 AMINO ACID TRANSPORTER LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 1 amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;neutral L-amino acid transmembrane transporter activity#GO:0015175;L-amino acid transmembrane transporter activity#GO:0015179 cellular process#GO:0009987;transport#GO:0006810;amino acid transport#GO:0006865;localization#GO:0051179;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000039464.1|UniProtKB=A0A5F8HBG0 A0A5F8HBG0 LOC100023471 PTHR26450:SF24 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR FAMILY 52 SUBFAMILY AC MEMBER 1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001893.4|UniProtKB=F7EAP9 F7EAP9 PGS1 PTHR12586:SF1 CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE, MITOCHONDRIAL transferase#PC00220 MONDO|Ensembl=ENSMODG00000046871.1|UniProtKB=A0A5F8G4E5 A0A5F8G4E5 PTHR10614:SF8 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 3 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159 response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;signal transduction#GO:0007165;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cellular response to insulin stimulus#GO:0032869;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;insulin-like growth factor receptor signaling pathway#GO:0048009;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899 MONDO|Ensembl=ENSMODG00000025606.3|UniProtKB=F6QBY5 F6QBY5 PTHR45845:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 4B guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000002767.4|UniProtKB=F6YGY9 F6YGY9 SVOP PTHR24064:SF673 SOLUTE CARRIER FAMILY 22 MEMBER SYNAPTIC VESICLE 2-RELATED PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000041245.1|UniProtKB=A0A5F8HAH4 A0A5F8HAH4 SMIM13 PTHR36877:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 13 SMALL INTEGRAL MEMBRANE PROTEIN 13 MONDO|Ensembl=ENSMODG00000024669.3|UniProtKB=A0A5F8H5J0 A0A5F8H5J0 COX20 PTHR31586:SF1 CYTOCHROME C OXIDASE PROTEIN 20 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 oxidoreductase#PC00176;oxidase#PC00175 MONDO|Ensembl=ENSMODG00000039346.1|UniProtKB=A0A5F8H998 A0A5F8H998 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000016906.3|UniProtKB=F6X1F5 F6X1F5 SSTR5 PTHR24229:SF20 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 5 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;binding#GO:0005488;neuropeptide receptor activity#GO:0008188;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;regulation of establishment of protein localization#GO:0070201;cell communication#GO:0007154;regulation of secretion#GO:0051046;response to steroid hormone#GO:0048545;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of protein secretion#GO:0050708;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular response to steroid hormone stimulus#GO:0071383;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;regulation of insulin secretion#GO:0050796;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of hormone secretion#GO:0046883;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of protein transport#GO:0051223;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 MONDO|Ensembl=ENSMODG00000024887.2|UniProtKB=A0A5F8GXP5 A0A5F8GXP5 PTHR11749:SF3 RIBULOSE-5-PHOSPHATE-3-EPIMERASE RIBULOSE-PHOSPHATE 3-EPIMERASE isomerase activity#GO:0016853;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;D-ribulose-phosphate 3-epimerase activity#GO:0004750 metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;pentose-phosphate shunt#GO:0006098;glyceraldehyde-3-phosphate metabolic process#GO:0019682;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;pentose-phosphate shunt, non-oxidative branch#GO:0009052;nucleoside phosphate metabolic process#GO:0006753 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 Ascorbate degradation#P02729>L-xylulose-5-phosphate-3-epimerase#P02852 MONDO|Ensembl=ENSMODG00000004997.3|UniProtKB=F7F7C9 F7F7C9 PTHR34438:SF1 SI:DKEY-97L20.6 CHROMOSOME 2 OPEN READING FRAME 81 MONDO|Ensembl=ENSMODG00000040515.1|UniProtKB=A0A5F8G4E8 A0A5F8G4E8 ZNF697 PTHR23226:SF207 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 697 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000040062.1|UniProtKB=K7DZH1 K7DZH1 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000000539.3|UniProtKB=F6XMR1 F6XMR1 PRKACB PTHR24353:SF116 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT BETA catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 GABA-B receptor II signaling#P05731>PKA#P05752;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Endothelin signaling pathway#P00019>PKA#P00570;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Enkephalin release#P05913>PKA#P05972;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-c#P00707;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;CCKR signaling map#P06959>PKA-Calpha/beta/gamma#P07099 MONDO|Ensembl=ENSMODG00000005939.4|UniProtKB=F6WW73 F6WW73 CIMAP1B PTHR21580:SF19 SHIPPO-1-RELATED CILIARY MICROTUBULE ASSOCIATED PROTEIN 1B microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;sperm motility#GO:0097722;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;flagellated sperm motility#GO:0030317;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000005434.4|UniProtKB=F7D0P7 F7D0P7 DPYS PTHR11647:SF50 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;dihydropyrimidinase activity#GO:0004157;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;pyrimidine nucleobase metabolic process#GO:0006206;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleobase catabolic process#GO:0046113;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;primary metabolic process#GO:0044238;pyrimidine nucleobase catabolic process#GO:0006208 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 MONDO|Ensembl=ENSMODG00000014798.2|UniProtKB=F7DMR2 F7DMR2 HCRT PTHR15173:SF2 OREXIN HYPOCRETIN NEUROPEPTIDE PRECURSOR MONDO|Ensembl=ENSMODG00000002417.4|UniProtKB=F7EGW0 F7EGW0 GK PTHR10196:SF69 SUGAR KINASE GLYCEROL KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 neutral lipid metabolic process#GO:0006638;carbohydrate derivative biosynthetic process#GO:1901137;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;acylglycerol metabolic process#GO:0006639;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 carbohydrate kinase#PC00065;kinase#PC00137 MONDO|Ensembl=ENSMODG00000015208.3|UniProtKB=F6VKG8 F6VKG8 CMIP PTHR25480:SF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 73 C-MAF-INDUCING PROTEIN intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000017296.3|UniProtKB=A0A5F8GXQ8 A0A5F8GXQ8 JTB PTHR13041:SF3 JTB PROTEIN-RELATED PROTEIN JTB cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cell cycle process#GO:0022402;cell division#GO:0051301;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;midbody#GO:0030496 MONDO|Ensembl=ENSMODG00000021047.4|UniProtKB=A0A5F8GCD6 A0A5F8GCD6 LOC100015316 PTHR43963:SF4 CARBONYL REDUCTASE 1-RELATED CARBONYL REDUCTASE (NADPH) alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000049348.1|UniProtKB=A0A5F8G6L1 A0A5F8G6L1 PTHR22306:SF2 CHROMOSOME 7 OPEN READING FRAME 50 PROTEIN CHOLESIN MONDO|Ensembl=ENSMODG00000051132.1|UniProtKB=A0A5F8GDR8 A0A5F8GDR8 PTHR48001:SF27 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038483.1|UniProtKB=A0A5F8G3S9 A0A5F8G3S9 MODO-UC PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN protein binding#GO:0005515;antigen binding#GO:0003823;peptide binding#GO:0042277;signaling receptor binding#GO:0005102;binding#GO:0005488 positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of immune system process#GO:0002684;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of lymphocyte mediated immunity#GO:0002708;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000038673.1|UniProtKB=A0A5F8GZE0 A0A5F8GZE0 PTHR31792:SF3 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000013187.4|UniProtKB=A0A5F8GHT8 A0A5F8GHT8 PTHR10799:SF819 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 1 catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;positive regulation of transcription by RNA polymerase II#GO:0045944;heterochromatin organization#GO:0070828;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009;DNA helicase#PC00011 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000013675.5|UniProtKB=F6ST07 F6ST07 SNX21 PTHR20939:SF10 SORTING NEXIN 20, 21 SORTING NEXIN-21 phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000015162.4|UniProtKB=F7D796 F7D796 TGFBI PTHR10900:SF82 PERIOSTIN-RELATED TRANSFORMING GROWTH FACTOR-BETA-INDUCED PROTEIN IG-H3 protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cell adhesion#GO:0007155;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000025607.2|UniProtKB=F6QBX0 F6QBX0 PTHR13177:SF3 DEATH-ASSOCIATED PROTEIN 1 DEATH-ASSOCIATED PROTEIN 1 binding#GO:0005488;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021 negative regulation of translation#GO:0017148;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;negative regulation of catabolic process#GO:0009895;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of autophagy#GO:0010507;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;apoptotic signaling pathway#GO:0097190;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 MONDO|Ensembl=ENSMODG00000014508.4|UniProtKB=F7F6S9 F7F6S9 SYDE1 PTHR46150:SF2 RHO GTPASE-ACTIVATING PROTEIN 100F RHO GTPASE-ACTIVATING PROTEIN SYDE1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 regulation of cellular process#GO:0050794;cell migration#GO:0016477;cell motility#GO:0048870;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of Ras protein signal transduction#GO:0046578;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000042931.1|UniProtKB=A0A5F8HBA7 A0A5F8HBA7 LOC100020103 PTHR26450:SF411 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51A7 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012428.4|UniProtKB=F6PKE2 F6PKE2 PRRC2B PTHR14038:SF4 BAT2 HLA-B-ASSOCIATED TRANSCRIPT 2 PROTEIN PRRC2B binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000050911.1|UniProtKB=A0A5F8GH45 A0A5F8GH45 PTHR47462:SF1 VESICLE-ASSOCIATED MEMBRANE PROTEIN 5 VESICLE-ASSOCIATED MEMBRANE PROTEIN 5 Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;localization#GO:0051179;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;vesicle-mediated transport#GO:0016192;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;transport#GO:0006810;Golgi vesicle transport#GO:0048193 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000046213.1|UniProtKB=K7DZF1 K7DZF1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010911.4|UniProtKB=H9H8N2 H9H8N2 PTHR19282:SF487 TETRASPANIN CD151 ANTIGEN cell motility#GO:0048870;cell migration#GO:0016477;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000049888.1|UniProtKB=F7BM55 F7BM55 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000019064.4|UniProtKB=H9H795 H9H795 C5H22orf23 PTHR28348:SF1 UPF0193 PROTEIN EVG1 UPF0193 PROTEIN EVG1 MONDO|Ensembl=ENSMODG00000002865.4|UniProtKB=A0A5F8GRJ2 A0A5F8GRJ2 LIMS1 PTHR24210:SF13 LIM DOMAIN-CONTAINING PROTEIN LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 1 positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell-cell adhesion#GO:0098609;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;regulation of response to stimulus#GO:0048583;positive regulation of cell communication#GO:0010647;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cell adhesion#GO:0007155;regulation of signaling#GO:0023051 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;cytoplasm#GO:0005737;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;cell-cell junction#GO:0005911 cell junction protein#PC00070 Integrin signalling pathway#P00034>PINCH#P00921 MONDO|Ensembl=ENSMODG00000012812.5|UniProtKB=F7DYN8 F7DYN8 ATG2B PTHR13190:SF20 AUTOPHAGY-RELATED 2, ISOFORM A AUTOPHAGY-RELATED PROTEIN 2 HOMOLOG B lipid binding#GO:0008289;protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543 glycogen catabolic process#GO:0005980;reticulophagy#GO:0061709;macroautophagy#GO:0016236;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;pexophagy#GO:0000425;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;vacuole organization#GO:0007033;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component assembly#GO:0022607;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;polysaccharide catabolic process#GO:0000272;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;phagophore assembly site#GO:0000407 MONDO|Ensembl=ENSMODG00000046101.1|UniProtKB=A0A5F8GR70 A0A5F8GR70 C21orf91 PTHR15961:SF3 PROTEIN EURL HOMOLOG PROTEIN EURL HOMOLOG head development#GO:0060322;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;brain development#GO:0007420;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;animal organ development#GO:0048513;multicellular organism development#GO:0007275;central nervous system neuron differentiation#GO:0021953;neuron differentiation#GO:0030182;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of developmental process#GO:0050793;forebrain development#GO:0030900;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 MONDO|Ensembl=ENSMODG00000024270.2|UniProtKB=F6Z5U2 F6Z5U2 PTHR48018:SF168 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010244.4|UniProtKB=F6W6M8 F6W6M8 IGDCC4 PTHR10075:SF132 BASIGIN RELATED IMMUNOGLOBULIN SUPERFAMILY DCC SUBCLASS MEMBER 4 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000001431.4|UniProtKB=F7BCH7 F7BCH7 PTHR24096:SF260 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE ACSBG2 ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874 small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ligase#PC00142 MONDO|Ensembl=ENSMODG00000038085.1|UniProtKB=A0A5F8H6W8 A0A5F8H6W8 PTHR23211:SF0 TRANS-GOLGI NETWORK INTEGRAL MEMBRANE PROTEIN TGN38 TRANS-GOLGI NETWORK INTEGRAL MEMBRANE PROTEIN 2 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000015049.4|UniProtKB=F7FUW7 F7FUW7 NR2F6 PTHR24083:SF44 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP F MEMBER 6 sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;nervous system development#GO:0007399;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000006319.4|UniProtKB=F7B3S4 F7B3S4 SPC24 PTHR22142:SF2 KINETOCHORE PROTEIN SPC24 KINETOCHORE PROTEIN SPC24 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cellular process#GO:0009987;cell cycle process#GO:0022402;chromosome segregation#GO:0007059;cell cycle#GO:0007049 chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;outer kinetochore#GO:0000940;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687 MONDO|Ensembl=ENSMODG00000016174.3|UniProtKB=F7G8Q4 F7G8Q4 PTHR24256:SF219 TRYPTASE-RELATED SERINE PROTEASE 33 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000045993.1|UniProtKB=A0A5F8GDG3 A0A5F8GDG3 PTHR12264:SF21 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 MONDO|Ensembl=ENSMODG00000025468.3|UniProtKB=A0A5F8GTE9 A0A5F8GTE9 TPK1 PTHR13622:SF14 THIAMIN PYROPHOSPHOKINASE THIAMINE PYROPHOSPHOKINASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220;kinase#PC00137 Thiamin metabolism#P02780>Thiamine kinase#P03176 MONDO|Ensembl=ENSMODG00000018120.4|UniProtKB=F7F1Q7 F7F1Q7 CD200R1 PTHR21462:SF2 CELL SURFACE GLYCOPROTEIN OX2 RECEPTOR PRECURSOR CD200 RECEPTOR 1A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009883.5|UniProtKB=F6VD23 F6VD23 HCN4 PTHR45689:SF4 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 4 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249 regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391 transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000016414.3|UniProtKB=F7AT33 F7AT33 NLRC3 PTHR24106:SF284 NACHT, LRR AND CARD DOMAINS-CONTAINING NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 3 molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000038301.1|UniProtKB=A0A5F8HF00 A0A5F8HF00 BTF3 PTHR10351:SF28 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000008398.3|UniProtKB=F7BV07 F7BV07 monDomV1R1233 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000086.3|UniProtKB=F6QS84 F6QS84 P2RY8 PTHR24232:SF25 G-PROTEIN COUPLED RECEPTOR S-GERANYLGERANYL-GLUTATHIONE RECEPTOR P2RY8 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020581.4|UniProtKB=H9H7M3 H9H7M3 ANKFY1 PTHR24118:SF82 POTE ANKYRIN DOMAIN ANKYRIN REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;vesicle-mediated transport#GO:0016192;vacuolar transport#GO:0007034;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cytosolic transport#GO:0016482;lysosomal transport#GO:0007041;post-Golgi vesicle-mediated transport#GO:0006892;localization#GO:0051179;Golgi to vacuole transport#GO:0006896;cellular localization#GO:0051641 intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;retromer complex#GO:0030904;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000017483.4|UniProtKB=F7FEY3 F7FEY3 TMEM234 PTHR28668:SF1 TRANSMEMBRANE PROTEIN 234 TRANSMEMBRANE PROTEIN 234 MONDO|Ensembl=ENSMODG00000016067.4|UniProtKB=F7GIQ3 F7GIQ3 ACTR1B PTHR11937:SF195 ACTIN BETA-CENTRACTIN structural constituent of cytoskeleton#GO:0005200;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cytoskeletal adaptor activity#GO:0008093;protein-membrane adaptor activity#GO:0043495;structural molecule activity#GO:0005198 establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;nuclear migration#GO:0007097 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;actin cytoskeleton#GO:0015629;organelle#GO:0043226;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090 MONDO|Ensembl=ENSMODG00000017379.4|UniProtKB=F6VHU3 F6VHU3 ATXN7L1 PTHR15117:SF9 ATAXIN 7 RELATED ATAXIN-7-LIKE PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 MONDO|Ensembl=ENSMODG00000001249.3|UniProtKB=F7FWM8 F7FWM8 PTHR24329:SF362 HOMEOBOX PROTEIN ARISTALESS INTESTINE-SPECIFIC HOMEOBOX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000007666.4|UniProtKB=A0A5F8GXH5 A0A5F8GXH5 LOC100022970 PTHR43294:SF1 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 2 ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873 sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;export from cell#GO:0140352;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;potassium ion homeostasis#GO:0055075;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000020625.4|UniProtKB=F6ZAP5 F6ZAP5 TXK PTHR24418:SF247 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE TXK protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;non-membrane spanning protein tyrosine kinase activity#GO:0004715;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 MONDO|Ensembl=ENSMODG00000010082.3|UniProtKB=F6XMR9 F6XMR9 CHRNB3 PTHR18945:SF75 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-3 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;acetylcholine receptor activity#GO:0015464;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276 trans-synaptic signaling#GO:0099537;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;response to nitrogen compound#GO:1901698;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;neuromuscular synaptic transmission#GO:0007274;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221 transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotine pharmacodynamics pathway#P06587>CHRNB3#P06612 MONDO|Ensembl=ENSMODG00000018443.3|UniProtKB=F7CUH1 F7CUH1 ADA2 PTHR11409:SF39 ADENOSINE DEAMINASE ADENOSINE DEAMINASE 2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;adenosine deaminase activity#GO:0004000;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 purine-containing compound biosynthetic process#GO:0072522;purine nucleoside metabolic process#GO:0042278;nucleoside catabolic process#GO:0009164;nucleobase-containing small molecule catabolic process#GO:0034656;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule biosynthetic process#GO:0044283;purine nucleobase metabolic process#GO:0006144;purine-containing compound catabolic process#GO:0072523;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;nucleobase metabolic process#GO:0009112;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;adenosine metabolic process#GO:0046085;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;extracellular region#GO:0005576 deaminase#PC00088 MONDO|Ensembl=ENSMODG00000037751.1|UniProtKB=A0A5F8GCA2 A0A5F8GCA2 LOC100020741 PTHR48018:SF170 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5D3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004355.2|UniProtKB=F6WPU8 F6WPU8 TRAPPC14 PTHR16096:SF8 MICROTUBULE-ASSOCIATED PROTEIN 11 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 14 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 TRAPP complex#GO:0030008;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;TRAPPII protein complex#GO:1990071;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000045063.1|UniProtKB=A0A5F8GQN9 A0A5F8GQN9 PTHR48001:SF24 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016294.4|UniProtKB=F7ATY9 F7ATY9 NOP58 PTHR10894:SF1 NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58 NUCLEOLAR PROTEIN 58 snoRNA binding#GO:0030515;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000012292.4|UniProtKB=F7GF31 F7GF31 KNTC1 PTHR15688:SF1 KINETOCHORE-ASSOCIATED PROTEIN 1 KINETOCHORE-ASSOCIATED PROTEIN 1 binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;protein binding#GO:0005515 mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of cellular component organization#GO:0051129;localization#GO:0051179;cell communication#GO:0007154;organelle fission#GO:0048285;intracellular signal transduction#GO:0035556;negative regulation of chromosome organization#GO:2001251;organelle assembly#GO:0070925;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;macromolecule localization#GO:0033036;mitotic sister chromatid segregation#GO:0000070;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;intracellular protein localization#GO:0008104;regulation of chromosome organization#GO:0033044;negative regulation of cell cycle process#GO:0010948;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;kinetochore assembly#GO:0051382;cell cycle checkpoint signaling#GO:0000075;cellular component assembly#GO:0022607;regulation of cell cycle process#GO:0010564;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of cell cycle#GO:0045786;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;negative regulation of organelle organization#GO:0010639;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;kinetochore organization#GO:0051383;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;protein localization to kinetochore#GO:0034501;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;chromosome organization#GO:0051276;negative regulation of cellular process#GO:0048523;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;sister chromatid segregation#GO:0000819;negative regulation of cell cycle phase transition#GO:1901988;nuclear chromosome segregation#GO:0098813;negative regulation of mitotic nuclear division#GO:0045839;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;regulation of organelle organization#GO:0033043;nuclear division#GO:0000280;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of sister chromatid segregation#GO:0033046;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;negative regulation of chromosome segregation#GO:0051985;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;spindle#GO:0005819;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;microtubule#GO:0005874;spindle microtubule#GO:0005876;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000014479.4|UniProtKB=F6ZG40 F6ZG40 MAP3K6 PTHR11584:SF391 SERINE/THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 6 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;MAP kinase kinase kinase activity#GO:0004709;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;JNK cascade#GO:0007254;response to stimulus#GO:0050896;p38MAPK cascade#GO:0038066;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 FGF signaling pathway#P00021>MEKK1-5#P00634 MONDO|Ensembl=ENSMODG00000008967.3|UniProtKB=F7G221 F7G221 CSAD PTHR45677:SF16 GLUTAMATE DECARBOXYLASE-RELATED CYSTEINE SULFINIC ACID DECARBOXYLASE lyase activity#GO:0016829;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830 biosynthetic process#GO:0009058;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 MONDO|Ensembl=ENSMODG00000050452.1|UniProtKB=A0A5F8GTX3 A0A5F8GTX3 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000002837.5|UniProtKB=A0A5F8GHJ3 A0A5F8GHJ3 PALLD PTHR45080:SF41 CONTACTIN 5 PALLADIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 axon#GO:0030424;cell body#GO:0044297;neuron projection#GO:0043005;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000038453.1|UniProtKB=A0A5F8GNE1 A0A5F8GNE1 NCBP2AS2 PTHR41161:SF1 PROTEIN NCBP2AS2 PROTEIN NCBP2AS2 MONDO|Ensembl=ENSMODG00000008321.4|UniProtKB=F7G0P1 F7G0P1 ZSCAN23 PTHR23226:SF76 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 23 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009101.4|UniProtKB=A0A5F8GLM8 A0A5F8GLM8 HTATIP2 PTHR14097:SF7 OXIDOREDUCTASE HTATIP2 PROTEIN HTATIP2 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000008495.4|UniProtKB=F7FTR6 F7FTR6 ITK PTHR24418:SF61 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ITK_TSK non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cellular developmental process#GO:0048869;developmental process#GO:0032502;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;T cell differentiation#GO:0030217;cellular process#GO:0009987;anatomical structure development#GO:0048856;immune system process#GO:0002376;lymphocyte differentiation#GO:0030098;cell activation#GO:0001775;cell differentiation#GO:0030154;cell development#GO:0048468;leukocyte activation#GO:0045321;leukocyte differentiation#GO:0002521;T cell activation#GO:0042110;mononuclear cell differentiation#GO:1903131 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 MONDO|Ensembl=ENSMODG00000049120.1|UniProtKB=F7FK54 F7FK54 LOC100017000 PTHR26454:SF43 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007005.4|UniProtKB=F6XUE1 F6XUE1 LAMC1 PTHR10574:SF270 NETRIN/LAMININ-RELATED LAMININ SUBUNIT GAMMA-1 cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;tissue development#GO:0009888;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;neuron projection development#GO:0031175;axon guidance#GO:0007411;axon development#GO:0061564;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039 basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 MONDO|Ensembl=ENSMODG00000024417.2|UniProtKB=F7G5T5 F7G5T5 PTHR10454:SF13 CASPASE CASPASE-4 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197 positive regulation of neuron apoptotic process#GO:0043525;positive regulation of inflammatory response#GO:0050729;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;positive regulation of apoptotic process#GO:0043065;positive regulation of response to external stimulus#GO:0032103;defense response#GO:0006952;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;inflammatory response#GO:0006954;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cell death#GO:0008219;apoptotic process#GO:0006915;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;canonical inflammasome complex#GO:0061702 protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000008590.4|UniProtKB=F7CC88 F7CC88 PCNX2 PTHR12372:SF5 PECANEX PECANEX-LIKE PROTEIN 2 MONDO|Ensembl=ENSMODG00000017264.4|UniProtKB=A0A5F8H8N4 A0A5F8H8N4 PIGA PTHR45871:SF1 N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375 carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247;phospholipid metabolic process#GO:0006644;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796 MONDO|Ensembl=ENSMODG00000038074.1|UniProtKB=A0A5F8G4W4 A0A5F8G4W4 PTHR13338:SF4 UPF0240 PROTEIN NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 4 cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000007385.4|UniProtKB=A0A5F8H2L3 A0A5F8H2L3 LMO1 PTHR45787:SF2 LD11652P RHOMBOTIN-1 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000039531.1|UniProtKB=A0A5F8H9G6 A0A5F8H9G6 LOC100028551 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007831.4|UniProtKB=F7ETH0 F7ETH0 PC PTHR43778:SF4 PYRUVATE CARBOXYLASE PYRUVATE CARBOXYLASE, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity#GO:0016874 carbohydrate biosynthetic process#GO:0016051;carbohydrate metabolic process#GO:0005975;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;hexose biosynthetic process#GO:0019319;gluconeogenesis#GO:0006094;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;glucose metabolic process#GO:0006006;small molecule biosynthetic process#GO:0044283;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;ligase#PC00142 Pyruvate metabolism#P02772>Pyruvate Carboxylase#P03140 MONDO|Ensembl=ENSMODG00000016763.4|UniProtKB=A0A5F8H129 A0A5F8H129 CELF2 PTHR24012:SF699 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 2 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;cellular component assembly#GO:0022607;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of mRNA splicing, via spliceosome#GO:0048024;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions#GO:0000375;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000012772.4|UniProtKB=A0A5F8GYU8 A0A5F8GYU8 CDK12 PTHR24056:SF126 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 12 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944 transferase complex#GO:1990234;protein kinase complex#GO:1902911;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000005615.4|UniProtKB=F7CZC7 F7CZC7 RANBP10 PTHR12864:SF19 RAN BINDING PROTEIN 9-RELATED RAN-BINDING PROTEIN 10 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 organelle organization#GO:0006996;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;cytoskeleton organization#GO:0007010;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000023328.1|UniProtKB=F6V8Y0 F6V8Y0 LSM10 PTHR21196:SF1 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10 RNA binding#GO:0003723;snRNA binding#GO:0017069;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;cytoplasmic ribonucleoprotein granule#GO:0036464;nucleoplasm#GO:0005654;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000009221.4|UniProtKB=A0A5F8GIY7 A0A5F8GIY7 PTHR48225:SF6 HORMA DOMAIN-CONTAINING PROTEIN 1 HORMA DOMAIN-CONTAINING PROTEIN 2 regulation of reproductive process#GO:2000241;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;meiotic nuclear division#GO:0140013;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;synaptonemal complex assembly#GO:0007130;cellular component assembly#GO:0022607;cell cycle checkpoint signaling#GO:0000075;homologous chromosome pairing at meiosis#GO:0007129;regulation of cell cycle process#GO:0010564;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;homologous chromosome segregation#GO:0045143;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;nuclear division#GO:0000280 synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;synaptonemal structure#GO:0099086;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000000916.4|UniProtKB=A0A5F8G509 A0A5F8G509 LRBA PTHR13743:SF64 BEIGE/BEACH-RELATED LIPOPOLYSACCHARIDE-RESPONSIVE AND BEIGE-LIKE ANCHOR PROTEIN protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 macroautophagy#GO:0016236;cellular component assembly#GO:0022607;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;catabolic process#GO:0009056;cell junction organization#GO:0034330;cellular component organization#GO:0016043;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;synapse organization#GO:0050808;organelle assembly#GO:0070925 cytosol#GO:0005829;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000049129.1|UniProtKB=A0A5F8GDE2 A0A5F8GDE2 MYH2 PTHR45615:SF39 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-2 microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;actin filament binding#GO:0051015;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 muscle system process#GO:0003012;muscle contraction#GO:0006936;system process#GO:0003008;multicellular organismal process#GO:0032501 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867 MONDO|Ensembl=ENSMODG00000046899.1|UniProtKB=A0A5F8HH64 A0A5F8HH64 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000021020.3|UniProtKB=F6QZA7 F6QZA7 TMPRSS3 PTHR24253:SF86 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 3 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;nervous system process#GO:0050877;proteolysis#GO:0006508;sensory perception of sound#GO:0007605;primary metabolic process#GO:0044238;system process#GO:0003008;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000047381.1|UniProtKB=A0A5F8HJG2 A0A5F8HJG2 CCDC184 PTHR31554:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 184 COILED-COIL DOMAIN-CONTAINING PROTEIN 184 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000002648.2|UniProtKB=F7DIB1 F7DIB1 PTHR12265:SF30 TRANSMEMBRANE PROTEIN 53 TRANSMEMBRANE PROTEIN 53 MONDO|Ensembl=ENSMODG00000013697.4|UniProtKB=F6YAH2 F6YAH2 CTSA PTHR11802:SF502 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE LYSOSOMAL PROTECTIVE PROTEIN serine-type peptidase activity#GO:0008236;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000025741.3|UniProtKB=F6T1X8 F6T1X8 LOC100029463 PTHR22950:SF188 AMINO ACID TRANSPORTER PROTON-COUPLED AMINO ACID TRANSPORTER 1 solute:proton symporter activity#GO:0015295;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid transmembrane transporter activity#GO:0015171;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;neutral L-amino acid transmembrane transporter activity#GO:0015175;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;glycine transmembrane transporter activity#GO:0015187;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179 alanine transport#GO:0032328;amino acid transport#GO:0006865;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;glycine transport#GO:0015816;monoatomic cation transport#GO:0006812;localization#GO:0051179;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;monoatomic ion transport#GO:0006811;carboxylic acid transmembrane transport#GO:1905039 vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000004309.2|UniProtKB=A8E6F2 A8E6F2 PTHR11691:SF6 TYPE I INTERFERON INTERFERON KAPPA cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;protein binding#GO:0005515;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune response#GO:0006955;multicellular organismal process#GO:0032501;adaptive immune response#GO:0002250;response to other organism#GO:0051707;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;cell activation#GO:0001775;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;humoral immune response#GO:0006959;cell surface receptor signaling pathway#GO:0007166;leukocyte activation involved in immune response#GO:0002366;immune effector process#GO:0002252;natural killer cell activation#GO:0030101;B cell activation#GO:0042113;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;lymphocyte activation involved in immune response#GO:0002285;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;lymphocyte activation#GO:0046649;response to chemical#GO:0042221;T cell activation involved in immune response#GO:0002286;type I interferon-mediated signaling pathway#GO:0060337;B cell activation involved in immune response#GO:0002312;immune system process#GO:0002376;cell activation involved in immune response#GO:0002263;response to peptide#GO:1901652;T cell activation#GO:0042110;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083;interferon superfamily#PC00127 MONDO|Ensembl=ENSMODG00000016178.4|UniProtKB=F7G8P0 F7G8P0 PIGT PTHR12959:SF11 GPI TRANSAMIDASE COMPONENT PIG-T-RELATED GPI-ANCHOR TRANSAMIDASE COMPONENT PIGT biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;GPI anchored protein biosynthesis#GO:0180046;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;cytoplasm#GO:0005737;caspase complex#GO:0008303;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000010567.4|UniProtKB=F6YR31 F6YR31 EDN1 PTHR13874:SF10 ENDOTHELIN ENDOTHELIN-1 protein binding#GO:0005515;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;neuropeptide receptor binding#GO:0071855;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664 inorganic ion homeostasis#GO:0098771;regulation of muscle contraction#GO:0006937;calcium ion homeostasis#GO:0055074;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;muscle system process#GO:0003012;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of muscle system process#GO:0090257;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;muscle contraction#GO:0006936;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;regulation of system process#GO:0044057;regulation of anatomical structure size#GO:0090066;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;system process#GO:0003008;regulation of smooth muscle contraction#GO:0006940;cellular homeostasis#GO:0019725;positive regulation of biological process#GO:0048518;regulation of blood pressure#GO:0008217;monoatomic ion homeostasis#GO:0050801;regulation of systemic arterial blood pressure#GO:0003073;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;blood circulation#GO:0008015;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Endothelin signaling pathway#P00019>Pre-pro ET1-4#P00576;Endothelin signaling pathway#P00019>Big ET1-4#P00574;Endothelin signaling pathway#P00019>Pro ET1-4#P00571;Endothelin signaling pathway#P00019>ET1-4#P00588 MONDO|Ensembl=ENSMODG00000020454.4|UniProtKB=A0A5F8G9P2 A0A5F8G9P2 TXNL1 PTHR46115:SF1 THIOREDOXIN-LIKE PROTEIN 1 THIOREDOXIN-LIKE PROTEIN 1 protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 oxidoreductase#PC00176 Oxidative stress response#P00046>TRX#P01122 MONDO|Ensembl=ENSMODG00000047190.1|UniProtKB=A0A5F8HHN6 A0A5F8HHN6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000044462.1|UniProtKB=A0A5F8G6I9 A0A5F8G6I9 monDomV1R1293 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002896.3|UniProtKB=A0A5F8GZS8 A0A5F8GZS8 SFT2D2 PTHR23137:SF1 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN SFT2B MONDO|Ensembl=ENSMODG00000042213.1|UniProtKB=A0A5F8GCG0 A0A5F8GCG0 PTHR10880:SF48 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;chromatin#GO:0000785;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000006679.4|UniProtKB=F7FFU5 F7FFU5 SAAL1 PTHR23424:SF35 SERUM AMYLOID A PROTEIN SAAL1 regulation of cell population proliferation#GO:0042127;positive regulation of cell population proliferation#GO:0008284;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of epithelial cell proliferation#GO:0050679 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 transfer/carrier protein#PC00219;apolipoprotein#PC00052 MONDO|Ensembl=ENSMODG00000005343.5|UniProtKB=A0A5F8GM99 A0A5F8GM99 OXR1 PTHR23354:SF69 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED OXIDATION RESISTANCE PROTEIN 1 response to oxidative stress#GO:0006979;response to stimulus#GO:0050896;response to stress#GO:0006950 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000017805.3|UniProtKB=F7CFE3 F7CFE3 PTHR13710:SF162 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q1 ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853 cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromosome#GO:0005694;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA helicase#PC00011;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000014323.4|UniProtKB=F6V570 F6V570 TUBD1 PTHR11588:SF4 TUBULIN TUBULIN DELTA CHAIN GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;tubulin#PC00228 MONDO|Ensembl=ENSMODG00000014236.3|UniProtKB=F6T943 F6T943 LIN28A PTHR46109:SF2 PROTEIN LIN-28 PROTEIN LIN-28 HOMOLOG A nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;RNA biosynthetic process#GO:0032774;pre-miRNA processing#GO:0031054;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000041210.1|UniProtKB=A0A5F8HK15 A0A5F8HK15 MYOZ2 PTHR15941:SF9 MYOZENIN MYOZENIN-2 molecular condensate scaffold activity#GO:0140693;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 striated muscle cell development#GO:0055002;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;striated muscle tissue development#GO:0014706;muscle organ development#GO:0007517;cellular anatomical entity morphogenesis#GO:0032989;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;muscle tissue development#GO:0060537;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;cellular response to stimulus#GO:0051716;muscle cell development#GO:0055001;system process#GO:0003008;cellular developmental process#GO:0048869;developmental process#GO:0032502;multicellular organismal process#GO:0032501;tissue development#GO:0009888;skeletal muscle tissue development#GO:0007519 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;I band#GO:0031674;membraneless organelle#GO:0043228;sarcomere#GO:0030017 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000024746.3|UniProtKB=F6YZJ9 F6YZJ9 TMEM128 PTHR31134:SF1 TRANSMEMBRANE PROTEIN 128 TRANSMEMBRANE PROTEIN 128 MONDO|Ensembl=ENSMODG00000046894.1|UniProtKB=F6RJ79 F6RJ79 PTHR23093:SF20 SIMILAR TO CHROMOSOME 3 OPEN READING FRAME 20 SIMILAR TO HUMAN CHROMOSOME 3 OPEN READING FRAME 20 MONDO|Ensembl=ENSMODG00000037723.1|UniProtKB=A0A5F8H214 A0A5F8H214 PTHR10031:SF54 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT C2, MITOCHONDRIAL ATP synthase#PC00002;transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000011723.3|UniProtKB=F7FSY5 F7FSY5 PURA PTHR12611:SF2 PUR-TRANSCRIPTIONAL ACTIVATOR TRANSCRIPTIONAL ACTIVATOR PROTEIN PUR-ALPHA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000004610.4|UniProtKB=F6Y3N2 F6Y3N2 GNB2 PTHR19850:SF27 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(T) SUBUNIT BETA-2 signaling receptor complex adaptor activity#GO:0030159;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cytoplasmic side of membrane#GO:0098562;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;heterotrimeric G-protein#PC00117;G-protein#PC00020 Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Wnt signaling pathway#P00057>GBeta#P01457;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;PI3 kinase pathway#P00048>Gbetagamma#P01188;Endogenous cannabinoid signaling#P05730>Gbeta#P05745;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753;Enkephalin release#P05913>G-Protein (i)#P05974;GABA-B receptor II signaling#P05731>Gbeta#P05755;Enkephalin release#P05913>G-Protein (s)#P05977;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085 MONDO|Ensembl=ENSMODG00000010232.4|UniProtKB=F6VLL7 F6VLL7 UPF3B PTHR13112:SF1 UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN REGULATOR OF NONSENSE TRANSCRIPTS 3B mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;positive regulation of biosynthetic process#GO:0009891;positive regulation of translation#GO:0045727;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;positive regulation of protein metabolic process#GO:0051247;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000008300.4|UniProtKB=F7FTW2 F7FTW2 BCAP31 PTHR12701:SF15 BCR-ASSOCIATED PROTEIN, BAP B-CELL RECEPTOR-ASSOCIATED PROTEIN 31 molecular carrier activity#GO:0140104;ATP-dependent activity#GO:0140657;protein carrier activity#GO:0140597 response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of protein localization#GO:0045184;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;protein transport#GO:0015031;positive regulation of protein metabolic process#GO:0051247;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;positive regulation of cellular process#GO:0048522;establishment of localization#GO:0051234;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;intracellular protein localization#GO:0008104;transport#GO:0006810;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;primary metabolic process#GO:0044238;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;localization#GO:0051179;regulation of protein catabolic process#GO:0042176;ERAD pathway#GO:0036503;positive regulation of protein catabolic process#GO:0045732;response to endoplasmic reticulum stress#GO:0034976 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000001544.4|UniProtKB=F7EM58 F7EM58 PTHR15337:SF1 ANTERIOR GRADIENT PROTEIN-RELATED ANTERIOR GRADIENT PROTEIN 2 HOMOLOG defense response#GO:0006952;response to stimulus#GO:0050896;inflammatory response#GO:0006954;response to stress#GO:0006950 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000040268.1|UniProtKB=A0A5F8H7P9 A0A5F8H7P9 LOC100028568 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000020801.3|UniProtKB=A0A5F8GDN4 A0A5F8GDN4 PTHR12259:SF3 RGS-GAIP INTERACTING PROTEIN GIPC PDZ DOMAIN-CONTAINING PROTEIN GIPC2 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000021549.4|UniProtKB=F7DF10 F7DF10 ERCC2 PTHR11472:SF1 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;damaged DNA binding#GO:0003684;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;RNA metabolic process#GO:0016070;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-excision repair#GO:0006289;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA helicase#PC00011;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000011795.4|UniProtKB=F7CBU6 F7CBU6 FAN1 PTHR15749:SF4 FANCONI-ASSOCIATED NUCLEASE 1 FANCONI-ASSOCIATED NUCLEASE 1 MONDO|Ensembl=ENSMODG00000009945.3|UniProtKB=F6QMX3 F6QMX3 LIMD2 PTHR24206:SF103 OS06G0237300 PROTEIN LIM DOMAIN-CONTAINING PROTEIN 2 binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;cellular component assembly#GO:0022607;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;membrane#GO:0016020;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000002945.4|UniProtKB=A0A5F8H6J6 A0A5F8H6J6 PPP2R5A PTHR10257:SF6 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT ALPHA ISOFORM enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;protein phosphatase regulator activity#GO:0019888;phosphatase activator activity#GO:0019211 cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;chromosome organization#GO:0051276;meiotic sister chromatid cohesion#GO:0051177;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287 protein modifying enzyme#PC00260;protein phosphatase#PC00195 FGF signaling pathway#P00021>PP2A#P00629;Wnt signaling pathway#P00057>PP2A#P01438;EGF receptor signaling pathway#P00018>PP2A#P00547 MONDO|Ensembl=ENSMODG00000049099.1|UniProtKB=A0A5F8H4G9 A0A5F8H4G9 CD24 PTHR16676:SF0 SIGNAL TRANSDUCER CD24 SIGNAL TRANSDUCER CD24 protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 cell activation#GO:0001775;cellular process#GO:0009987;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;multicellular organismal process#GO:0032501 side of membrane#GO:0098552;membrane microdomain#GO:0098857;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane raft#GO:0045121;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000009408.4|UniProtKB=F7C5U5 F7C5U5 PLXNC1 PTHR22625:SF4 PLEXIN PLEXIN-C1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signaling#GO:0023052;synapse assembly#GO:0007416;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of multicellular organismal development#GO:2000026;regulation of cell shape#GO:0008360;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;positive regulation of axonogenesis#GO:0050772;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;positive regulation of cell development#GO:0010720;cellular component assembly#GO:0022607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;cellular component biogenesis#GO:0044085;regulation of axonogenesis#GO:0050770;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of cell differentiation#GO:0045597;cell surface receptor signaling pathway#GO:0007166;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;system development#GO:0048731;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell differentiation#GO:0045595;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017043.3|UniProtKB=F6XZT5 F6XZT5 ZNF512B PTHR22979:SF3 ZINC FINGER PROTEIN-RELATED ZINC FINGER PROTEIN 512B MONDO|Ensembl=ENSMODG00000017028.4|UniProtKB=A0A5F8G6K6 A0A5F8G6K6 DNAJC5 PTHR44027:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5 regulation of transport#GO:0051049;regulation of localization#GO:0032879;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;biological regulation#GO:0065007;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;protein folding#GO:0006457;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;primary metabolic process#GO:0044238 cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;presynapse#GO:0098793 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000028269.2|UniProtKB=K7E4A9 K7E4A9 PTHR15211:SF0 GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE GASTRIC INHIBITORY POLYPEPTIDE signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 response to stimulus#GO:0050896;response to stress#GO:0006950;response to nutrient levels#GO:0031667;response to starvation#GO:0042594 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000019422.4|UniProtKB=H9H7D2 H9H7D2 GTSF1 PTHR21402:SF9 GAMETOCYTE SPECIFIC FACTOR 1-RELATED GAMETOCYTE-SPECIFIC FACTOR 1 MONDO|Ensembl=ENSMODG00000007988.3|UniProtKB=F7D5P5 F7D5P5 PTHR11143:SF23 60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER RIBOSOMAL PROTEIN L26 LIKE 1 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000002474.4|UniProtKB=A0A5F8HID6 A0A5F8HID6 SPOCK3 PTHR13866:SF21 SPARC OSTEONECTIN TESTICAN-3 enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;molecular function inhibitor activity#GO:0140678;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;peptidase inhibitor activity#GO:0030414;ion binding#GO:0043167;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;calcium ion binding#GO:0005509;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000000847.3|UniProtKB=A0A5F8GNT3 A0A5F8GNT3 PTHR23411:SF32 TAPASIN T CELL RECEPTOR BETA CONSTANT 2 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;signaling receptor complex#GO:0043235 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>TCR Beta#P01299 MONDO|Ensembl=ENSMODG00000011273.4|UniProtKB=F6WZR8 F6WZR8 TLN2 PTHR19981:SF34 TALIN TALIN-2 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cell adhesion#GO:0007155;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;focal adhesion#GO:0005925;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;cell junction#GO:0030054;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000020412.4|UniProtKB=F7BEA3 F7BEA3 ZFR PTHR45762:SF21 ZINC FINGER RNA-BINDING PROTEIN ZINC FINGER RNA-BINDING PROTEIN single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000015291.3|UniProtKB=F6T6J4 F6T6J4 GPANK1 PTHR20923:SF1 BAT4 PROTEIN-RELATED G PATCH DOMAIN AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000019298.4|UniProtKB=F7ARU5 F7ARU5 SCARB2 PTHR11923:SF118 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 LYSOSOME MEMBRANE PROTEIN 2 cargo receptor activity#GO:0038024 cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;lysosomal transport#GO:0007041;protein localization to vacuole#GO:0072665;endocytosis#GO:0006897;protein localization to organelle#GO:0033365;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;protein localization to lysosome#GO:0061462;import into cell#GO:0098657;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;receptor-mediated endocytosis#GO:0006898;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;vacuolar transport#GO:0007034;vesicle-mediated transport#GO:0016192;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;membrane#GO:0016020;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000007962.4|UniProtKB=A0A5F8GRF7 A0A5F8GRF7 SLC25A35 PTHR45928:SF2 RE38146P SOLUTE CARRIER FAMILY 25 MEMBER 35 MONDO|Ensembl=ENSMODG00000001145.4|UniProtKB=F6VPN6 F6VPN6 PTHR10502:SF29 ANNEXIN ANNEXIN A11 lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;phospholipid binding#GO:0005543;binding#GO:0005488 cytokinetic process#GO:0032506;transport#GO:0006810;cytokinesis#GO:0000910;phagocytosis#GO:0006909;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;cell division#GO:0051301;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;endocytosis#GO:0006897 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle#GO:0031982;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000003755.4|UniProtKB=F7GBS1 F7GBS1 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008825.4|UniProtKB=F6XVI0 F6XVI0 EGLN1 PTHR12907:SF4 EGL NINE HOMOLOG-RELATED EGL NINE HOMOLOG 1 ferrous iron binding#GO:0008198;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;iron ion binding#GO:0005506;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;dioxygenase activity#GO:0051213;metal ion binding#GO:0046872;cation binding#GO:0043169 cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to oxygen levels#GO:0070482;regulation of programmed cell death#GO:0043067;response to decreased oxygen levels#GO:0036293;cellular response to hypoxia#GO:0071456;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to hypoxia#GO:0001666;regulation of apoptotic process#GO:0042981;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Hypoxia response via HIF activation#P00030>Prolyl Hydroxylase#P00821 MONDO|Ensembl=ENSMODG00000000199.3|UniProtKB=F6TFG8 F6TFG8 LOC100013840 PTHR15608:SF0 SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2 17S U2 SNRNP COMPLEX COMPONENT HTATSF1 chromatin-protein adaptor activity#GO:0140463;RNA binding#GO:0003723;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;intracellular protein localization#GO:0008104;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;protein localization to organelle#GO:0033365;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;localization#GO:0051179;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 U2 snRNP#GO:0005686;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;site of double-strand break#GO:0035861;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;spliceosomal snRNP complex#GO:0097525;chromosome#GO:0005694;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000045793.1|UniProtKB=A0A5F8GWN3 A0A5F8GWN3 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000037891.1|UniProtKB=A0A5F8GTF6 A0A5F8GTF6 PTHR21856:SF7 FIBROUS SHEATH-INTERACTING PROTEIN 2 FIBROUS SHEATH-INTERACTING PROTEIN 2 MONDO|Ensembl=ENSMODG00000038722.1|UniProtKB=A0A5F8GJS5 A0A5F8GJS5 PTHR26453:SF0 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13D1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001817.5|UniProtKB=F6T5N2 F6T5N2 ELK4 PTHR11849:SF21 ETS ETS DOMAIN-CONTAINING PROTEIN ELK-4 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>ELK#P01140;CCKR signaling map#P06959>SAP1#P07097;Interleukin signaling pathway#P00036>ELK#P00962 MONDO|Ensembl=ENSMODG00000036541.1|UniProtKB=A0A5F8HLX7 A0A5F8HLX7 PRXL2C PTHR28630:SF34 FAMILY NOT NAMED PEROXIREDOXIN-LIKE 2C MONDO|Ensembl=ENSMODG00000009818.4|UniProtKB=F6SFE6 F6SFE6 VIM PTHR45652:SF5 GLIAL FIBRILLARY ACIDIC PROTEIN VIMENTIN structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;cytoskeleton organization#GO:0007010;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;axon#GO:0030424;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 intermediate filament#PC00129;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000013845.5|UniProtKB=F6X6L0 F6X6L0 PTHR19282:SF263 TETRASPANIN LEUKOCYTE ANTIGEN CD37 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007328.4|UniProtKB=F7EF03 F7EF03 SLC25A19 PTHR24089:SF59 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL THIAMINE PYROPHOSPHATE CARRIER organophosphate ester transmembrane transporter activity#GO:0015605;quaternary ammonium group transmembrane transporter activity#GO:0015651;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;organophosphate ester transport#GO:0015748;vitamin transport#GO:0051180;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000008547.4|UniProtKB=F7DH01 F7DH01 SGCD PTHR12939:SF6 SARCOGLYCAN DELTA-SARCOGLYCAN heart process#GO:0003015;circulatory system development#GO:0072359;circulatory system process#GO:0003013;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;system development#GO:0048731;muscle tissue development#GO:0060537;multicellular organismal process#GO:0032501;tissue development#GO:0009888;heart development#GO:0007507;blood circulation#GO:0008015;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;cardiac muscle tissue development#GO:0048738;animal organ development#GO:0048513;multicellular organism development#GO:0007275;heart contraction#GO:0060047;system process#GO:0003008 sarcolemma#GO:0042383;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000023784.3|UniProtKB=F6WQP0 F6WQP0 PTHR14112:SF1 SYNOVIAL SARCOMA, X MEMBER KRAB-RELATED DOMAIN-CONTAINING PROTEIN transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000007282.4|UniProtKB=F7FQK1 F7FQK1 GGA3 PTHR45905:SF3 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA3 binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267 Golgi to plasma membrane transport#GO:0006893;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;post-Golgi vesicle-mediated transport#GO:0006892;localization within membrane#GO:0051668;transport#GO:0006810;Golgi vesicle transport#GO:0048193 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000010610.4|UniProtKB=F7G822 F7G822 LOC100028071 PTHR24286:SF397 CYTOCHROME P450 26 LANOSTEROL 14-ALPHA DEMETHYLASE oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;secondary alcohol biosynthetic process#GO:1902653;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126 oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000002138.4|UniProtKB=F6U008 F6U008 SEMA5A PTHR11036:SF78 SEMAPHORIN SEMAPHORIN-5A signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cellular process#GO:0050794;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;developmental growth#GO:0048589;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;axonogenesis#GO:0007409;neuron development#GO:0048666;neuron projection extension#GO:1990138;developmental growth involved in morphogenesis#GO:0060560;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;axon extension#GO:0048675;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cell growth#GO:0016049;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;growth#GO:0040007;neuron differentiation#GO:0030182 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000019507.4|UniProtKB=F6VU03 F6VU03 SOX12 PTHR10270:SF221 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-12 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;camera-type eye development#GO:0043010;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;visual system development#GO:0150063;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;negative regulation of cellular process#GO:0048523;sensory organ development#GO:0007423;developmental process#GO:0032502;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;camera-type eye morphogenesis#GO:0048593;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;eye development#GO:0001654;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;sensory organ morphogenesis#GO:0090596;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;neuron differentiation#GO:0030182;positive regulation of macromolecule metabolic process#GO:0010604;head development#GO:0060322;nervous system development#GO:0007399;sensory system development#GO:0048880;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000017139.4|UniProtKB=F6TMP1 F6TMP1 SHC1 PTHR10337:SF2 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 1 molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;receptor tyrosine kinase binding#GO:0030971;protein-macromolecule adaptor activity#GO:0030674;kinase binding#GO:0019900;binding#GO:0005488;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;enzyme binding#GO:0019899;protein binding#GO:0005515;signaling adaptor activity#GO:0035591 ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;cellular response to nitrogen compound#GO:1901699;epidermal growth factor receptor signaling pathway#GO:0007173;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to insulin stimulus#GO:0032869;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;response to nitrogen compound#GO:1901698;response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Shc#P00183;CCKR signaling map#P06959>SHC1 @EGFR#P07083;FGF signaling pathway#P00021>Shc#P00639;CCKR signaling map#P06959>p52 SHC1#P07151;Integrin signalling pathway#P00034>Shc#P00949;Ras Pathway#P04393>Shc#P04579;PDGF signaling pathway#P00047>Shc#P01175;CCKR signaling map#P06959>p66 SHC1#P07168;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Shc#P00865;Interleukin signaling pathway#P00036>Shc#P00997;CCKR signaling map#P06959>SHC1#P07138;CCKR signaling map#P06959>p46 SHC1#P07098;EGF receptor signaling pathway#P00018>Shc#P00554 MONDO|Ensembl=ENSMODG00000043599.1|UniProtKB=A0A5F8H8K1 A0A5F8H8K1 ALKBH4 PTHR12463:SF0 OXYGENASE-RELATED ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 4 oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 midbody#GO:0030496;contractile ring#GO:0070938;cellular anatomical structure#GO:0110165 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000019829.4|UniProtKB=F7GFL5 F7GFL5 PAMR1 PTHR24254:SF9 PROTHROMBIN INACTIVE SERINE PROTEASE PAMR1 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000009870.4|UniProtKB=A0A5F8GY52 A0A5F8GY52 GPHN PTHR10192:SF33 MOLYBDOPTERIN BIOSYNTHESIS PROTEIN GEPHYRIN catalytic activity#GO:0003824;transferase activity#GO:0016740 phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein localization to membrane#GO:0072657;cell junction organization#GO:0034330;postsynapse organization#GO:0099173;localization within membrane#GO:0051668;receptor clustering#GO:0043113;synapse organization#GO:0050808;organophosphate biosynthetic process#GO:0090407;cellular localization#GO:0051641;protein metabolic process#GO:0019538;localization#GO:0051179;macromolecule localization#GO:0033036;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;membrane organization#GO:0061024;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;neuromuscular junction development#GO:0007528;intracellular protein localization#GO:0008104 synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;neuron projection#GO:0043005;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;dendritic tree#GO:0097447;intracellular anatomical structure#GO:0005622;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 MONDO|Ensembl=ENSMODG00000006147.4|UniProtKB=F7BSP1 F7BSP1 SYT17 PTHR10024:SF348 SYNAPTOTAGMIN SYNAPTOTAGMIN-17 molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;protein binding#GO:0005515;binding#GO:0005488;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;transport#GO:0006810;regulation of secretion#GO:0051046;localization#GO:0051179;establishment of localization#GO:0051234;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000038827.1|UniProtKB=F6XCS7 F6XCS7 PTHR11430:SF86 LIPOCALIN PROSTAGLANDIN-H2 D-ISOMERASE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000018521.3|UniProtKB=F7AG64 F7AG64 SLC38A2 PTHR22950:SF207 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID SYMPORTER 2 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;localization#GO:0051179;establishment of localization#GO:0051234;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;amino acid transport#GO:0006865 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;amino acid transporter#PC00046 MONDO|Ensembl=ENSMODG00000005222.3|UniProtKB=F6ZD24 F6ZD24 SEL1L2 PTHR11102:SF53 SEL-1-LIKE PROTEIN PROTEIN SEL-1 HOMOLOG 2 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000003840.3|UniProtKB=F7EBQ4 F7EBQ4 PTHR11441:SF0 THYMIDINE KINASE THYMIDINE KINASE, CYTOSOLIC transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;deoxynucleoside kinase activity#GO:0019136;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205 nucleoside monophosphate biosynthetic process#GO:0009124;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 kinase#PC00137;nucleotide kinase#PC00172 Salvage pyrimidine deoxyribonucleotides#P02774>Deoxyuridine kinase#P03146;Salvage pyrimidine deoxyribonucleotides#P02774>Thymidine kinase#P03147 MONDO|Ensembl=ENSMODG00000013316.4|UniProtKB=F6YVJ3 F6YVJ3 EPB41L4A PTHR23280:SF4 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 4A cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000015452.4|UniProtKB=F6S3Z6 F6S3Z6 ZKSCAN2 PTHR23226:SF164 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000001405.4|UniProtKB=F7F564 F7F564 FERD3L PTHR23349:SF63 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FER3-LIKE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000014132.4|UniProtKB=F6XKS9 F6XKS9 KIFC1 PTHR24115:SF1045 KINESIN-RELATED KINESIN-LIKE PROTEIN KIFC1 binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111 organelle assembly#GO:0070925;nuclear division#GO:0000280;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;microtubule cytoskeleton organization involved in mitosis#GO:1902850;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;mitotic cell cycle#GO:0000278;microtubule-based movement#GO:0007018;mitotic spindle organization#GO:0007052;chromosome segregation#GO:0007059;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;mitotic spindle assembly#GO:0090307;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000039434.1|UniProtKB=F6VIJ7 F6VIJ7 PTHR11581:SF0 30S/40S RIBOSOMAL PROTEIN S4 RIBOSOMAL PROTEIN S4 Y1-RELATED structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000008251.4|UniProtKB=A0A5F8GD26 A0A5F8GD26 LYST PTHR13743:SF86 BEIGE/BEACH-RELATED LYSOSOMAL-TRAFFICKING REGULATOR vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;lysosome organization#GO:0007040;lytic vacuole organization#GO:0080171;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013934.4|UniProtKB=F6SCP9 F6SCP9 PTHR24256:SF140 TRYPTASE-RELATED SERINE PROTEASE 45-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000013033.4|UniProtKB=F7GBN5 F7GBN5 SARDH PTHR13847:SF200 SARCOSINE DEHYDROGENASE-RELATED SARCOSINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000004217.4|UniProtKB=A0A5F8G9E0 A0A5F8G9E0 HNRNPAB PTHR48033:SF1 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A_B nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000018802.4|UniProtKB=F6ZMF1 F6ZMF1 ELOVL5 PTHR11157:SF18 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 5 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042;transferase#PC00220 MONDO|Ensembl=ENSMODG00000019750.4|UniProtKB=F6WN96 F6WN96 OLFML2A PTHR23192:SF29 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 2A cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000009377.4|UniProtKB=F7CPY4 F7CPY4 RUFY1 PTHR45956:SF4 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN RUN AND FYVE DOMAIN-CONTAINING PROTEIN 1 localization#GO:0051179;establishment of localization#GO:0051234;regulation of transport#GO:0051049;intracellular protein localization#GO:0008104;regulation of localization#GO:0032879;protein transport#GO:0015031;regulation of endocytosis#GO:0030100;transport#GO:0006810;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000015711.2|UniProtKB=A0A5F8GUA9 A0A5F8GUA9 SLC5A6 PTHR42985:SF2 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-DEPENDENT MULTIVITAMIN TRANSPORTER monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 vitamin transport#GO:0051180;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;nitrogen compound transport#GO:0071705;sodium ion transport#GO:0006814;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;monocarboxylic acid transport#GO:0015718;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000014064.3|UniProtKB=A0ACM8QJT0 A0ACM8QJT0 SPMIP8 PTHR35348:SF1 TESTIS, PROSTATE AND PLACENTA-EXPRESSED PROTEIN SPERM MICROTUBULE INNER PROTEIN 8 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;A axonemal microtubule#GO:0097649;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;axonemal doublet microtubule#GO:0097545;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;intracellular organelle#GO:0043229;cilium#GO:0005929;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;cytoplasmic microtubule#GO:0005881;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879 MONDO|Ensembl=ENSMODG00000003629.4|UniProtKB=A0A5F8GZR1 A0A5F8GZR1 PTHR11375:SF22 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER B protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 regulation of apoptotic process#GO:0042981;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000003961.4|UniProtKB=A0A5F8GSD7 A0A5F8GSD7 PITPNC1 PTHR10658:SF55 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CYTOPLASMIC PHOSPHATIDYLINOSITOL TRANSFER PROTEIN 1 lipid carrier activity#GO:0005319;ion binding#GO:0043167;phosphatidylcholine intramembrane carrier activity#GO:0008525;anion binding#GO:0043168;small molecule binding#GO:0036094;cation binding#GO:0043169;intramembrane lipid carrier activity#GO:0140303;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol transfer activity#GO:0008526;phosphatidylcholine binding#GO:0031210;molecular carrier activity#GO:0140104;binding#GO:0005488;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transporter#PC00227 MONDO|Ensembl=ENSMODG00000028339.2|UniProtKB=K7E3U2 K7E3U2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000005408.4|UniProtKB=F7FVQ5 F7FVQ5 LRP12 PTHR24270:SF47 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 12 cell migration#GO:0016477;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell motility#GO:0048870;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 apolipoprotein#PC00052;transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000049552.1|UniProtKB=A0A5F8HHK9 A0A5F8HHK9 CAVIN4 PTHR15240:SF4 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 4 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;membrane raft#GO:0045121;caveola#GO:0005901;cell periphery#GO:0071944;plasma membrane raft#GO:0044853;intracellular anatomical structure#GO:0005622;membrane microdomain#GO:0098857 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000009451.3|UniProtKB=A0A5F8GY84 A0A5F8GY84 UBE2N PTHR24068:SF141 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 N ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631 protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;protein K63-linked ubiquitination#GO:0070534;response to stress#GO:0006950;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Toll receptor signaling pathway#P00054>Ubc13#P01381 MONDO|Ensembl=ENSMODG00000012595.4|UniProtKB=F7DYL1 F7DYL1 PTHR23226:SF430 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 1010-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016560.3|UniProtKB=H9H6Z3 H9H6Z3 ACO2 PTHR43160:SF3 ACONITATE HYDRATASE B ACONITATE HYDRATASE, MITOCHONDRIAL catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;hydro-lyase activity#GO:0016836;iron-sulfur cluster binding#GO:0051536;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 hydratase#PC00120;lyase#PC00144 TCA cycle#P00051>Aconitase#P01268 MONDO|Ensembl=ENSMODG00000013767.4|UniProtKB=A0A5F8G7Y2 A0A5F8G7Y2 PAFAH1B2 PTHR11852:SF1 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT ALPHA2 hydrolase activity#GO:0016787;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;carboxylic ester hydrolase activity#GO:0052689;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;male gamete generation#GO:0048232;gamete generation#GO:0007276;developmental process#GO:0032502;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;multicellular organismal reproductive process#GO:0048609 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000004814.4|UniProtKB=F6V5H3 F6V5H3 RAB24 PTHR24073:SF471 DRAB5-RELATED RAS-RELATED PROTEIN RAB-24 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;autophagosome#GO:0005776;endosome#GO:0005768;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;intracellular vesicle#GO:0097708;vesicle#GO:0031982 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000022800.3|UniProtKB=H9H951 H9H951 PTHR19306:SF6 STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6 binding#GO:0005488;nucleic acid binding#GO:0003676;damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725 membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;site of double-strand break#GO:0035861;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000046497.1|UniProtKB=H9H789 H9H789 LOC100015840 PTHR26454:SF59 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001260.4|UniProtKB=F7CJ36 F7CJ36 SGK2 PTHR24356:SF197 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE SGK2 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;ion channel regulator activity#GO:0099106;transferase activity#GO:0016740;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;protein serine/threonine kinase activity#GO:0004674;channel regulator activity#GO:0016247;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000010290.4|UniProtKB=A0A5F8G986 A0A5F8G986 SLC25A40 PTHR45760:SF5 FI19922P1-RELATED MITOCHONDRIAL GLUTATHIONE TRANSPORTER SLC25A40 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000013643.4|UniProtKB=F7EW43 F7EW43 PTHR12622:SF21 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX2-RELATED ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;response to stimulus#GO:0050896;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;signaling#GO:0023052;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000002176.3|UniProtKB=F7GEG9 F7GEG9 PTHR21229:SF11 LUNG SEVEN TRANSMEMBRANE RECEPTOR PROTEIN GPR108 negative regulation of signal transduction#GO:0009968;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;negative regulation of signaling#GO:0023057 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000039793.1|UniProtKB=A0A5F8GH23 A0A5F8GH23 PTHR24332:SF15 HOMEOBOX PROTEIN CDX HOMEOBOX PROTEIN CDX-4 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;anterior/posterior axis specification#GO:0009948;cellular developmental process#GO:0048869;developmental process#GO:0032502;anterior/posterior pattern specification#GO:0009952;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;tube development#GO:0035295;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;embryonic pattern specification#GO:0009880;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000012795.4|UniProtKB=F7EFU1 F7EFU1 ORC6 PTHR13394:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 6 ORIGIN RECOGNITION COMPLEX SUBUNIT 6 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;origin recognition complex#GO:0000808;nuclear origin of replication recognition complex#GO:0005664 replication origin binding protein#PC00199;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000044699.1|UniProtKB=A0A5F8GSD2 A0A5F8GSD2 LBX1 PTHR24336:SF9 TRANSCRIPTION FACTOR LBX TRANSCRIPTION FACTOR LBX1 transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000001314.3|UniProtKB=F7BEH8 F7BEH8 PTHR22792:SF61 LUPUS LA PROTEIN-RELATED LA RIBONUCLEOPROTEIN DOMAIN FAMILY MEMBER 6 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000004692.4|UniProtKB=F6TQS4 F6TQS4 M1AP PTHR28642:SF1 MEIOSIS 1 ARREST PROTEIN MEIOSIS 1 ARREST PROTEIN male gamete generation#GO:0048232;male meiotic nuclear division#GO:0007140;organelle organization#GO:0006996;cellular process#GO:0009987;chromosome separation#GO:0051304;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;meiotic chromosome segregation#GO:0045132;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;spermatogenesis#GO:0007283;developmental process#GO:0032502;gamete generation#GO:0007276;reproductive process#GO:0022414;meiotic cell cycle process#GO:1903046;developmental process involved in reproduction#GO:0003006;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;organelle fission#GO:0048285;multicellular organismal reproductive process#GO:0048609;nuclear division#GO:0000280;sexual reproduction#GO:0019953 MONDO|Ensembl=ENSMODG00000008716.3|UniProtKB=A0A5F8H4C2 A0A5F8H4C2 PTPDC1 PTHR23339:SF123 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE DOMAIN-CONTAINING PROTEIN 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000023037.3|UniProtKB=A0A5F8H658 A0A5F8H658 LOC100030265 PTHR24376:SF38 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 544-RELATED gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000003073.2|UniProtKB=F6PLH7 F6PLH7 MDH1 PTHR23382:SF34 MALATE DEHYDROGENASE MALATE DEHYDROGENASE, CYTOPLASMIC oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 pyridine-containing compound metabolic process#GO:0072524;oxoacid metabolic process#GO:0043436;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 dehydrogenase#PC00092 TCA cycle#P00051>Malate Dehydrogenase#P01270 MONDO|Ensembl=ENSMODG00000015702.4|UniProtKB=F7DGI0 F7DGI0 TLCD3B PTHR13439:SF15 CT120 PROTEIN CERAMIDE SYNTHASE acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;biosynthetic process#GO:0009058;homeostatic process#GO:0042592;lipid biosynthetic process#GO:0008610;ceramide biosynthetic process#GO:0046513;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;ceramide metabolic process#GO:0006672 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000006406.4|UniProtKB=A0A5F8HFU9 A0A5F8HFU9 SCN3A PTHR10037:SF237 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 3 SUBUNIT ALPHA transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;passive transmembrane transporter activity#GO:0022803;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated sodium channel activity#GO:0005248;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 transmission of nerve impulse#GO:0019226;system process#GO:0003008;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;multicellular organismal process#GO:0032501;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;nervous system process#GO:0050877;sensory perception#GO:0007600;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;sodium ion transport#GO:0006814;action potential#GO:0001508;sensory perception of pain#GO:0019233 cation channel complex#GO:0034703;transporter complex#GO:1990351;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;axon#GO:0030424;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000001677.4|UniProtKB=F6SQ46 F6SQ46 LOC100030263 PTHR47966:SF13 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED CHYMOSIN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;aspartic protease#PC00053 MONDO|Ensembl=ENSMODG00000040633.1|UniProtKB=A0A5F8H6N0 A0A5F8H6N0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000002360.4|UniProtKB=A0A5F8GCL4 A0A5F8GCL4 DCBLD2 PTHR46806:SF3 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN DISCOIDIN, CUB AND LCCL DOMAIN-CONTAINING PROTEIN 2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;wound healing#GO:0042060;response to wounding#GO:0009611;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000012690.3|UniProtKB=F6VFJ3 F6VFJ3 AMN1 PTHR13382:SF46 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B PROTEIN AMN1 HOMOLOG intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000028942.1|UniProtKB=K7E294 K7E294 PTHR24365:SF554 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 13 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;regulation of innate immune response#GO:0045088;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;cell communication#GO:0007154;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of response to external stimulus#GO:0032101;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;toll-like receptor signaling pathway#GO:0002224;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028749.2|UniProtKB=K7E2K9 K7E2K9 PTHR46815:SF1 PROTEIN KISH-B PROTEIN KISH-B MONDO|Ensembl=ENSMODG00000000163.4|UniProtKB=F6XS87 F6XS87 SESN3 PTHR12474:SF4 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN-3 amino acid binding#GO:0016597;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;ion binding#GO:0043167;carboxylic acid binding#GO:0031406;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;organic acid binding#GO:0043177;cation binding#GO:0043169;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 regulation of macroautophagy#GO:0016241;negative regulation of TORC1 signaling#GO:1904262;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;response to chemical#GO:0042221;response to acid chemical#GO:0001101;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;positive regulation of macroautophagy#GO:0016239;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;cellular response to nitrogen compound#GO:1901699;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;response to nitrogen compound#GO:1901698;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594 oxidoreductase#PC00176;peroxidase#PC00180 MONDO|Ensembl=ENSMODG00000029666.2|UniProtKB=K7E5G5 K7E5G5 PTHR23036:SF163 CYTOKINE RECEPTOR CYTOKINE RECEPTOR-LIKE FACTOR 2 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955 cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016649.4|UniProtKB=F7GGT1 F7GGT1 DHX33 PTHR18934:SF118 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX33 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase I#GO:0006356;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase I#GO:0045943;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000017498.3|UniProtKB=F7F1B2 F7F1B2 PTHR11430:SF142 LIPOCALIN LIPOCALIN_CYTOSOLIC FATTY-ACID BINDING DOMAIN-CONTAINING PROTEIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000023720.2|UniProtKB=F6UVI5 F6UVI5 LOC100029143 PTHR24229:SF38 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 1 molecular transducer activity#GO:0060089;binding#GO:0005488;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;biological regulation#GO:0065007;response to estradiol#GO:0032355;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 MONDO|Ensembl=ENSMODG00000049844.1|UniProtKB=A0A5F8GV66 A0A5F8GV66 GPR50 PTHR24228:SF53 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR MELATONIN RECEPTOR TYPE 1A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 MONDO|Ensembl=ENSMODG00000015819.4|UniProtKB=F7FE37 F7FE37 ACADL PTHR48083:SF20 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;binding#GO:0005488;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;catalytic activity#GO:0003824 long-chain fatty acid metabolic process#GO:0001676;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;carnitine metabolic process#GO:0009437;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000048827.1|UniProtKB=F6SGC1 F6SGC1 PTHR11909:SF20 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242;Hedgehog signaling pathway#P00025>Casein kinase I#P00681 MONDO|Ensembl=ENSMODG00000010122.3|UniProtKB=F6WNM4 F6WNM4 ZFP36L1 PTHR12547:SF53 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36L1 RNA binding#GO:0003723;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA 3'-UTR binding#GO:0003730;translation regulator activity#GO:0045182;protein-RNA adaptor activity#GO:0140517;molecular adaptor activity#GO:0060090 positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000005216.3|UniProtKB=F7A1V8 F7A1V8 ACER3 PTHR46187:SF3 ALKALINE CERAMIDASE 3 ALKALINE CERAMIDASE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;primary metabolic process#GO:0044238;sphingoid biosynthetic process#GO:0046520;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000016526.3|UniProtKB=F7EPL9 F7EPL9 PTHR11005:SF15 LYSOSOMAL ACID LIPASE-RELATED GASTRIC TRIACYLGLYCEROL LIPASE lipase activity#GO:0016298;catalytic activity#GO:0003824;triacylglycerol lipase activity#GO:0004806;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 lipase#PC00143;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000017184.3|UniProtKB=F6XYF9 F6XYF9 LRRC26 PTHR46473:SF2 GH08155P LEUCINE-RICH REPEAT-CONTAINING PROTEIN 26 potassium channel activity#GO:0005267;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;channel regulator activity#GO:0016247;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772;binding#GO:0005488;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;potassium channel regulator activity#GO:0015459;voltage-gated channel activity#GO:0022832;protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324;molecular function activator activity#GO:0140677;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000044954.1|UniProtKB=F7B2H2 F7B2H2 LOC100018754 PTHR26450:SF141 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000193.4|UniProtKB=A0A5F8G9T1 A0A5F8G9T1 CLASP1 PTHR21567:SF28 CLASP CLIP-ASSOCIATING PROTEIN 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;spindle organization#GO:0007051;establishment of localization#GO:0051234;establishment of spindle localization#GO:0051293;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;organelle assembly#GO:0070925;organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;chromosome segregation#GO:0007059;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;establishment of mitotic spindle localization#GO:0040001;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;nuclear division#GO:0000280;cellular localization#GO:0051641;spindle localization#GO:0051653;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;mitotic spindle organization#GO:0007052;establishment of organelle localization#GO:0051656 condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;chromosome#GO:0005694;cytoplasmic microtubule#GO:0005881;basal part of cell#GO:0045178;kinetochore#GO:0000776;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitotic spindle#GO:0072686;intracellular organelle#GO:0043229;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;supramolecular fiber#GO:0099512 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000002870.4|UniProtKB=F7E278 F7E278 GPR161 PTHR22752:SF10 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 161 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 endosome#GO:0005768;intracellular organelle#GO:0043229;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004275.4|UniProtKB=F6TEM9 F6TEM9 DDX25 PTHR47958:SF33 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX25 macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;localization#GO:0051179;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810 cytoplasmic stress granule#GO:0010494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000005017.4|UniProtKB=F7ERJ3 F7ERJ3 PLOD3 PTHR10730:SF7 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER MULTIFUNCTIONAL PROCOLLAGEN LYSINE HYDROXYLASE AND GLYCOSYLTRANSFERASE LH3 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;hexosyltransferase activity#GO:0016758;dioxygenase activity#GO:0051213;glucosyltransferase activity#GO:0046527 collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;extracellular region#GO:0005576;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000024853.1|UniProtKB=F7AXD9 F7AXD9 LOC100013427 PTHR12010:SF2 40S RIBOSOMAL PROTEIN S29 SMALL RIBOSOMAL SUBUNIT PROTEIN US14 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;structural molecule activity#GO:0005198;zinc ion binding#GO:0008270;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000015893.4|UniProtKB=F7AGM2 F7AGM2 CENPO PTHR14582:SF1 INNER KINETOCHORE SUBUNIT MAL2 CENTROMERE PROTEIN O kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000016881.2|UniProtKB=F6Y152 F6Y152 PTK6 PTHR24418:SF265 TYROSINE-PROTEIN KINASE PROTEIN-TYROSINE KINASE 6 catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;binding#GO:0005488;signaling receptor binding#GO:0005102;non-membrane spanning protein tyrosine kinase activity#GO:0004715 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular developmental process#GO:0048869;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 MONDO|Ensembl=ENSMODG00000046545.1|UniProtKB=A0A5F8GX27 A0A5F8GX27 LOC103105060 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000045560.1|UniProtKB=F7EU63 F7EU63 IAH1 PTHR14209:SF19 ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 HOMOLOG hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 hydrolase#PC00121;esterase#PC00097;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000003587.4|UniProtKB=A0A5F8GA69 A0A5F8GA69 CSNK1D PTHR11909:SF519 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM DELTA protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 positive regulation of catabolic process#GO:0009896;spindle organization#GO:0007051;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of catabolic process#GO:0009894;plasma membrane bounded cell projection assembly#GO:0120031;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of circadian rhythm#GO:0042752;microtubule cytoskeleton organization#GO:0000226;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;non-motile cilium assembly#GO:1905515;cell communication#GO:0007154;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;organelle assembly#GO:0070925;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;cell cycle#GO:0007049;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;chromosome segregation#GO:0007059;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;cytoskeleton organization#GO:0007010;regulation of protein metabolic process#GO:0051246;regulation of canonical Wnt signaling pathway#GO:0060828;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;cilium organization#GO:0044782;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;cell projection organization#GO:0030030;response to stimulus#GO:0050896;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;cellular component organization#GO:0016043;cilium assembly#GO:0060271;membraneless organelle assembly#GO:0140694;positive regulation of proteasomal protein catabolic process#GO:1901800;cell cycle process#GO:0022402;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Parkinson disease#P00049>Casein kinase I#P01242;Circadian clock system#P00015>Casein kinase I#P00502;Wnt signaling pathway#P00057>Casein Kinase 1#P01460;CCKR signaling map#P06959>CK1delta/epsilon#P07089 MONDO|Ensembl=ENSMODG00000004460.4|UniProtKB=F6R6P6 F6R6P6 CCDC148 PTHR21549:SF1 MUTATED IN BLADDER CANCER 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 148 MONDO|Ensembl=ENSMODG00000011357.4|UniProtKB=F6T5E4 F6T5E4 HIGD1B PTHR12297:SF9 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1B cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000023862.3|UniProtKB=A0A5F8GT79 A0A5F8GT79 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000041614.1|UniProtKB=A0A5F8HJV0 A0A5F8HJV0 B3GNT7 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 primary metabolic process#GO:0044238;aminoglycan biosynthetic process#GO:0006023;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000019732.3|UniProtKB=F6X401 F6X401 STRBP PTHR45762:SF1 ZINC FINGER RNA-BINDING PROTEIN SPERMATID PERINUCLEAR RNA-BINDING PROTEIN double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000023782.2|UniProtKB=F7FC42 F7FC42 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004754.3|UniProtKB=F6XIA8 F6XIA8 NT5M PTHR16504:SF6 5'(3')-DEOXYRIBONUCLEOTIDASE 5'(3')-DEOXYRIBONUCLEOTIDASE, MITOCHONDRIAL phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253 nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117 MONDO|Ensembl=ENSMODG00000028960.2|UniProtKB=K7DZB9 K7DZB9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000003445.4|UniProtKB=F7DWW8 F7DWW8 MARCHF11 PTHR46053:SF1 E3 UBIQUITIN-PROTEIN LIGASE MARCH4-LIKE E3 UBIQUITIN-PROTEIN LIGASE MARCHF11 ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000050748.1|UniProtKB=A0A5F8GVU2 A0A5F8GVU2 PTHR11927:SF9 GALACTOSIDE 2-L-FUCOSYLTRANSFERASE L-FUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000028477.2|UniProtKB=K7E5H7 K7E5H7 DMAC2L PTHR13382:SF10 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B ATP SYNTHASE SUBUNIT S, MITOCHONDRIAL intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000015051.5|UniProtKB=F7FUV6 F7FUV6 WNK4 PTHR13902:SF114 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK4 molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;phosphotransferase activity, alcohol group as acceptor#GO:0016773;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;protein serine/threonine kinase activity#GO:0004674 regulation of metal ion transport#GO:0010959;negative regulation of transport#GO:0051051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic cation transmembrane transport#GO:1904062;chemical homeostasis#GO:0048878 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000043324.1|UniProtKB=A0A5F8HI13 A0A5F8HI13 CPLX4 PTHR16705:SF7 COMPLEXIN COMPLEXIN-4 SNARE binding#GO:0000149;binding#GO:0005488;protein binding#GO:0005515 signal release#GO:0023061;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;regulation of signaling#GO:0023051;secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;export from cell#GO:0140352;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;regulated exocytosis#GO:0045055;regulation of transport#GO:0051049;exocytosis#GO:0006887;regulation of localization#GO:0032879;vesicle-mediated transport in synapse#GO:0099003;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;synaptic signaling#GO:0099536;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177 presynapse#GO:0098793;neuron projection#GO:0043005;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;cell junction#GO:0030054;membrane protein complex#GO:0098796;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;neuron projection terminus#GO:0044306;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;axon#GO:0030424;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000002367.4|UniProtKB=F7GDA7 F7GDA7 PPP4R4 PTHR21467:SF0 PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 PPP4R4 SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494 phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000015638.3|UniProtKB=F7FEK1 F7FEK1 NUPR1 PTHR17149:SF5 NUCLEAR PROTEIN 1 AND 2 NUCLEAR PROTEIN 1 regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;negative regulation of cell population proliferation#GO:0008285;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cell population proliferation#GO:0042127;negative regulation of cell cycle#GO:0045786;negative regulation of cellular process#GO:0048523 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000020096.4|UniProtKB=F7ESC9 F7ESC9 LOC100618988 PTHR10068:SF8 BONE MARROW PROTEOGLYCAN PROTEOGLYCAN 3 extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000002485.3|UniProtKB=F7BVU0 F7BVU0 LAMB3 PTHR10574:SF268 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-3 cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;generation of neurons#GO:0048699;cellular component assembly#GO:0022607;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;substrate adhesion-dependent cell spreading#GO:0034446;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell motility#GO:0048870;cell-substrate adhesion#GO:0031589;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;system development#GO:0048731;external encapsulating structure organization#GO:0045229;tissue development#GO:0009888;multicellular organismal process#GO:0032501;cell migration#GO:0016477;extracellular matrix assembly#GO:0085029;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;basement membrane#GO:0005604;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 MONDO|Ensembl=ENSMODG00000043486.1|UniProtKB=A0A5F8HA00 A0A5F8HA00 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000000145.4|UniProtKB=A0A5F8G9M1 A0A5F8G9M1 TTYH3 PTHR12424:SF4 TWEETY-RELATED PROTEIN TWEETY HOMOLOG 3 gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000023942.1|UniProtKB=F7F878 F7F878 SSTR2 PTHR24229:SF6 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 2 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;binding#GO:0005488;neuropeptide receptor activity#GO:0008188;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 cellular response to steroid hormone stimulus#GO:0071383;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725;biological regulation#GO:0065007;response to estradiol#GO:0032355;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to steroid hormone#GO:0048545;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 MONDO|Ensembl=ENSMODG00000020951.3|UniProtKB=F6SP99 F6SP99 PTHR15088:SF0 NUCLEAR FACTOR RIP140 NUCLEAR RECEPTOR-INTERACTING PROTEIN 1 nuclear estrogen receptor binding#GO:0030331;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;circadian regulation of gene expression#GO:0032922;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;rhythmic process#GO:0048511;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;response to estradiol#GO:0032355;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000016652.4|UniProtKB=F7G787 F7G787 PTHR31742:SF1 RPA-INTERACTING PROTEIN RPAIN RPA-INTERACTING PROTEIN localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000043259.1|UniProtKB=A0A5F8HL00 A0A5F8HL00 PTHR12025:SF12 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR B molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;molecular function activator activity#GO:0140677;protein binding#GO:0005515;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to growth factor stimulus#GO:0071363;angiogenesis#GO:0001525;sprouting angiogenesis#GO:0002040;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;circulatory system development#GO:0072359;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of chemotaxis#GO:0050920;vascular endothelial growth factor receptor signaling pathway#GO:0048010;response to endogenous stimulus#GO:0009719;positive regulation of cell motility#GO:2000147;response to abiotic stimulus#GO:0009628;blood vessel morphogenesis#GO:0048514;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;positive regulation of response to external stimulus#GO:0032103;cell surface receptor signaling pathway#GO:0007166;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;system development#GO:0048731;cell communication#GO:0007154;regulation of cell motility#GO:2000145;positive regulation of chemotaxis#GO:0050921;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to growth factor#GO:0070848;regulation of leukocyte migration#GO:0002685;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;positive regulation of locomotion#GO:0040017;response to hypoxia#GO:0001666;regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;tube development#GO:0035295;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000016612.5|UniProtKB=H9H709 H9H709 SREBF2 PTHR46062:SF3 STEROL REGULATORY ELEMENT-BINDING PROTEIN STEROL REGULATORY ELEMENT-BINDING PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of localization#GO:0032879;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000042361.1|UniProtKB=A0A5F8HJ35 A0A5F8HJ35 LOC100026919 PTHR48018:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015043.4|UniProtKB=F7G5B5 F7G5B5 SLC4A3 PTHR11453:SF15 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN 3 monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291 regulation of biological quality#GO:0065008;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;biological regulation#GO:0065007;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000049123.1|UniProtKB=A0A5F8GCL6 A0A5F8GCL6 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018115.5|UniProtKB=F7F207 F7F207 PNISR PTHR31518:SF3 ARGININE/SERINE-RICH PROTEIN PNISR ARGININE_SERINE-RICH PROTEIN PNISR MONDO|Ensembl=ENSMODG00000021550.4|UniProtKB=F7DF01 F7DF01 AVL9 PTHR31017:SF1 LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED LATE SECRETORY PATHWAY PROTEIN AVL9 HOMOLOG intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000023238.2|UniProtKB=F6UCX2 F6UCX2 KCNA3 PTHR11537:SF28 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 3 transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;action potential#GO:0001508;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;transmembrane transporter complex#GO:1902495;axon#GO:0030424 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000027693.2|UniProtKB=K7E5G2 K7E5G2 FAM237A PTHR36690:SF2 PROTEIN FAM237A PROTEIN FAM237A MONDO|Ensembl=ENSMODG00000012679.4|UniProtKB=F6VGC3 F6VGC3 TGFBR1 PTHR23255:SF61 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II TGF-BETA RECEPTOR TYPE-1 protein kinase activity#GO:0004672;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;signaling receptor activity#GO:0038023;activin binding#GO:0048185;transforming growth factor beta receptor activity#GO:0005024;kinase activity#GO:0016301;transferase activity#GO:0016740;molecular transducer activity#GO:0060089;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824 response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;circulatory system development#GO:0072359;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;activin receptor signaling pathway#GO:0032924;cellular response to growth factor stimulus#GO:0071363;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;signal transduction#GO:0007165;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;animal organ development#GO:0048513;endothelial cell proliferation#GO:0001935;epithelial cell proliferation#GO:0050673;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;response to transforming growth factor beta#GO:0071559;cell population proliferation#GO:0008283;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;system development#GO:0048731;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;signaling receptor complex#GO:0043235;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 serine/threonine protein kinase receptor#PC00205 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 MONDO|Ensembl=ENSMODG00000016259.4|UniProtKB=F7C1V8 F7C1V8 SERPINI2 PTHR11461:SF51 SERINE PROTEASE INHIBITOR, SERPIN SERPIN I2 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000019356.3|UniProtKB=A0A5F8GSV6 A0A5F8GSV6 NDUFB8 PTHR12840:SF1 NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000045326.1|UniProtKB=A0A5F8G2E9 A0A5F8G2E9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000042554.1|UniProtKB=A0A5F8GYC0 A0A5F8GYC0 PTHR19339:SF0 T CELL RECEPTOR ALPHA VARIABLE 39 T CELL RECEPTOR ALPHA VARIABLE 41 MONDO|Ensembl=ENSMODG00000014300.4|UniProtKB=A0A5F8HK71 A0A5F8HK71 MED15 PTHR31804:SF3 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575 MONDO|Ensembl=ENSMODG00000029041.2|UniProtKB=F6TA74 F6TA74 PTHR14611:SF6 TECTONIC FAMILY MEMBER TECTONIC-2 smoothened signaling pathway#GO:0007224;cilium organization#GO:0044782;cell communication#GO:0007154;localization#GO:0051179;organelle assembly#GO:0070925;signaling#GO:0023052;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cilium assembly#GO:0060271;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection assembly#GO:0120031;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;signal transduction#GO:0007165;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;ciliary transition zone#GO:0035869;cilium#GO:0005929;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000004875.4|UniProtKB=F7CKQ0 F7CKQ0 PTHR12560:SF6 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 ceramide metabolic process#GO:0006672;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000019717.2|UniProtKB=F6XME5 F6XME5 LOC100017520 PTHR48001:SF165 OLFACTORY RECEPTOR OLFACTORY RECEPTOR FAMILY 1 SUBFAMILY AH MEMBER 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037768.1|UniProtKB=A0A5F8GCX9 A0A5F8GCX9 LOC100028022 PTHR26452:SF310 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000931.4|UniProtKB=F7F811 F7F811 SH3GL1 PTHR14167:SF63 SH3 DOMAIN-CONTAINING ENDOPHILIN-A2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cytoplasm#GO:0005737;cytosol#GO:0005829;presynapse#GO:0098793 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007863.4|UniProtKB=F7EBB8 F7EBB8 CUZD1 PTHR14002:SF27 ENDOGLIN/TGF-BETA RECEPTOR TYPE III CUB AND ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019812.4|UniProtKB=F7G123 F7G123 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017458.2|UniProtKB=A0A5F8H652 A0A5F8H652 LOC100009992 PTHR24070:SF388 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE KRAS hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;Ras protein signal transduction#GO:0007265;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GTP#P01280;VEGF signaling pathway#P00056>Ras#P01411;Integrin signalling pathway#P00034>Ras#P00916;Ras Pathway#P04393>Ras#P04547;EGF receptor signaling pathway#P00018>Ras#P00552;TGF-beta signaling pathway#P00052>Ras-GDP#P01291;PDGF signaling pathway#P00047>Ras#P01154;FGF signaling pathway#P00021>Ras#P00633;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;p53 pathway feedback loops 2#P04398>Ras#P04651;Angiogenesis#P00005>Ras#P00238;PI3 kinase pathway#P00048>Ras#P01182 MONDO|Ensembl=ENSMODG00000025520.3|UniProtKB=F6VJ19 F6VJ19 AFP PTHR11385:SF7 SERUM ALBUMIN-RELATED ALPHA-FETOPROTEIN binding#GO:0005488;small molecule binding#GO:0036094 response to nutrient levels#GO:0031667;response to stimulus#GO:0050896 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000017956.4|UniProtKB=F7E330 F7E330 AK9 PTHR23359:SF148 NUCLEOTIDE KINASE ADENYLATE KINASE 9 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 kinase#PC00137;nucleotide kinase#PC00172 MONDO|Ensembl=ENSMODG00000018160.4|UniProtKB=F7CD07 F7CD07 NAA50 PTHR42919:SF41 N-ALPHA-ACETYLTRANSFERASE N-ALPHA-ACETYLTRANSFERASE 50 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;N-acetyltransferase activity#GO:0008080;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;protein N-acyltransferase activity#GO:0140186 mitotic sister chromatid cohesion#GO:0007064;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;chromosome organization#GO:0051276;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840 protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;acetyltransferase complex#GO:1902493;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 transferase#PC00220;acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000023875.2|UniProtKB=F7G9B8 F7G9B8 PTAFR PTHR24233:SF6 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PLATELET-ACTIVATING FACTOR RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000004755.4|UniProtKB=F6XI91 F6XI91 KLHL36 PTHR45632:SF4 LD33804P KELCH-LIKE PROTEIN 36 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein binding#GO:0005515;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;enzyme-substrate adaptor activity#GO:0140767 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;Cul3-RING ubiquitin ligase complex#GO:0031463 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010726.4|UniProtKB=A0A5F8HHH0 A0A5F8HHH0 USP11 PTHR21646:SF29 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 11 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000006622.4|UniProtKB=F7GEQ3 F7GEQ3 ZNF410 PTHR46179:SF3 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 410 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000025268.3|UniProtKB=F7AQZ1 F7AQZ1 LOC130455120 PTHR12015:SF188 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 10 binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;response to external biotic stimulus#GO:0043207;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;cell motility#GO:0048870;regulation of cellular process#GO:0050794;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cytokine-mediated signaling pathway#GO:0019221;response to bacterium#GO:0009617;cell chemotaxis#GO:0060326;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;biological regulation#GO:0065007;response to other organism#GO:0051707;cell migration#GO:0016477;leukocyte migration#GO:0050900;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;cellular response to molecule of bacterial origin#GO:0071219;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to molecule of bacterial origin#GO:0002237;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;response to peptide#GO:1901652;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;response to cytokine#GO:0034097;neutrophil migration#GO:1990266;response to chemical#GO:0042221;taxis#GO:0042330;granulocyte migration#GO:0097530;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;cell surface receptor signaling pathway#GO:0007166;neutrophil chemotaxis#GO:0030593;response to lipopolysaccharide#GO:0032496 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000025645.3|UniProtKB=F6XVN8 F6XVN8 PTHR12011:SF455 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E3 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000029800.2|UniProtKB=K7E4Q2 K7E4Q2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000040201.1|UniProtKB=H9H658 H9H658 monDomV1R1292 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007113.4|UniProtKB=F6SI34 F6SI34 CD68 PTHR11506:SF2 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN MACROSIALIN establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;establishment of protein localization#GO:0045184 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000044747.1|UniProtKB=A0A5F8GGF2 A0A5F8GGF2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001693.5|UniProtKB=F6S7G3 F6S7G3 GHITM PTHR23291:SF112 BAX INHIBITOR-RELATED GROWTH HORMONE-INDUCIBLE TRANSMEMBRANE PROTEIN calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular component organization#GO:0016043;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;transport#GO:0006810;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;inner mitochondrial membrane organization#GO:0007007;mitochondrial membrane organization#GO:0007006;mitochondrial calcium ion transmembrane transport#GO:0006851;organelle organization#GO:0006996;monoatomic ion transmembrane transport#GO:0034220;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;monoatomic cation transmembrane transport#GO:0098655 organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000050540.1|UniProtKB=A0A5F8HEK6 A0A5F8HEK6 PTHR11388:SF89 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1B1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;secondary active transmembrane transporter activity#GO:0015291;bile acid transmembrane transporter activity#GO:0015125;active transmembrane transporter activity#GO:0022804 lipid transport#GO:0006869;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;bile acid and bile salt transport#GO:0015721 membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000041458.1|UniProtKB=A0A5F8HH16 A0A5F8HH16 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000018690.4|UniProtKB=F7AEC3 F7AEC3 MAP3K2 PTHR24361:SF342 MITOGEN-ACTIVATED KINASE KINASE KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;PDGF signaling pathway#P00047>ERK#P01143;B cell activation#P00010>MEKK#P00369;FGF signaling pathway#P00021>MEKK1-5#P00634;EGF receptor signaling pathway#P00018>MEKK1-5#P00553;Integrin signalling pathway#P00034>ERK#P00907 MONDO|Ensembl=ENSMODG00000039749.1|UniProtKB=A0A5F8HEU0 A0A5F8HEU0 LOC100028631 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008262.4|UniProtKB=F6Z8P9 F6Z8P9 XPO4 PTHR12596:SF1 EXPORTIN 4,7-RELATED EXPORTIN-4 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;nuclear export#GO:0051168;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;protein export from nucleus#GO:0006611;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 MONDO|Ensembl=ENSMODG00000019126.4|UniProtKB=F7EUN0 F7EUN0 RASL10B PTHR46350:SF1 RAS LIKE FAMILY 10 MEMBER B-RELATED RAS-LIKE PROTEIN FAMILY MEMBER 10B MONDO|Ensembl=ENSMODG00000002958.4|UniProtKB=F6PJT6 F6PJT6 TDP1 PTHR12415:SF0 TYROSYL-DNA PHOSPHODIESTERASE 1 TYROSYL-DNA PHOSPHODIESTERASE 1 nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;hydrolase activity#GO:0016787;double-stranded DNA binding#GO:0003690;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;catalytic activity, acting on DNA#GO:0140097 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000004390.3|UniProtKB=F6SVT1 F6SVT1 MRPS14 PTHR19836:SF31 30S RIBOSOMAL PROTEIN S14 SMALL RIBOSOMAL SUBUNIT PROTEIN US14M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000006216.4|UniProtKB=F7FSA6 F7FSA6 PNPLA3 PTHR12406:SF22 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE PNPLA3 transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;triacylglycerol lipase activity#GO:0004806;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 phospholipid biosynthetic process#GO:0008654;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;homeostatic process#GO:0042592;phospholipid metabolic process#GO:0006644;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;glycerolipid catabolic process#GO:0046503;triglyceride catabolic process#GO:0019433;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;lipid catabolic process#GO:0016042;neutral lipid metabolic process#GO:0006638;acylglycerol catabolic process#GO:0046464;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;triglyceride metabolic process#GO:0006641;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;neutral lipid catabolic process#GO:0046461 organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000025750.3|UniProtKB=A0A5F8G7D6 A0A5F8G7D6 LOC100020779 PTHR11559:SF179 CARBOXYLESTERASE LIVER CARBOXYLESTERASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;short-chain fatty acid catabolic process#GO:0019626;fatty acid catabolic process#GO:0009062;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 esterase#PC00097 MONDO|Ensembl=ENSMODG00000041605.1|UniProtKB=A0A5F8GVB0 A0A5F8GVB0 PTHR26451:SF344 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10J1 binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000040360.1|UniProtKB=A0A5F8GQ96 A0A5F8GQ96 DBR1 PTHR12849:SF0 RNA LARIAT DEBRANCHING ENZYME LARIAT DEBRANCHING ENZYME hydrolase activity#GO:0016787;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;catabolic process#GO:0009056;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound catabolic process#GO:0034655 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000015070.3|UniProtKB=F7FHA1 F7FHA1 BABAM1 PTHR15660:SF2 BRISC AND BRCA1-A COMPLEX MEMBER 1 BRISC AND BRCA1-A COMPLEX MEMBER 1 DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;mitotic G2/M transition checkpoint#GO:0044818;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000043076.1|UniProtKB=A0A5F8HEG4 A0A5F8HEG4 SLC26A6 PTHR11814:SF113 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 6 secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;dicarboxylic acid transmembrane transporter activity#GO:0005310;carboxylic acid transmembrane transporter activity#GO:0046943 monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;chloride transmembrane transport#GO:1902476;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;chloride transport#GO:0006821 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000011065.3|UniProtKB=F7EMB1 F7EMB1 PTHR24028:SF318 CADHERIN-87A PROTOCADHERIN BETA-16 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000021086.4|UniProtKB=F6UJ06 F6UJ06 DIPK2B PTHR32073:SF8 GH11358P DIVERGENT PROTEIN KINASE DOMAIN 2B MONDO|Ensembl=ENSMODG00000019332.4|UniProtKB=F6XSS6 F6XSS6 ABHD15 PTHR10794:SF39 ABHYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD15 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000011859.2|UniProtKB=F7GDB6 F7GDB6 PTHR23063:SF21 PHOSPHOLIPID ACYLTRANSFERASE LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 acyltransferase#PC00042;transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000003333.2|UniProtKB=F7DCX9 F7DCX9 PTHR24103:SF676 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000000399.4|UniProtKB=A0A5F8HKZ2 A0A5F8HKZ2 RPRD1A PTHR12460:SF2 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 1A binding#GO:0005488;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 kinase inhibitor#PC00139;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000050258.1|UniProtKB=A0A5F8H1T4 A0A5F8H1T4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012090.4|UniProtKB=A0A5F8GAY8 A0A5F8GAY8 ITGA3 PTHR23220:SF89 INTEGRIN ALPHA INTEGRIN ALPHA-3 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 MONDO|Ensembl=ENSMODG00000044712.1|UniProtKB=A0A5F8GBF0 A0A5F8GBF0 PTHR10840:SF0 PROGRAMMED CELL DEATH PROTEIN 5 PROGRAMMED CELL DEATH PROTEIN 5 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000001575.4|UniProtKB=F7BX00 F7BX00 SRSF2 PTHR23147:SF22 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 2 nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000017851.4|UniProtKB=A0A5F8GTB2 A0A5F8GTB2 CCNDBP1 PTHR15492:SF1 CYCLIN D1-BINDING PROTEIN 1 CYCLIN-D1-BINDING PROTEIN 1 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000000023.2|UniProtKB=A0A5F8HEX3 A0A5F8HEX3 PTHR21237:SF25 GRPE PROTEIN GRPE PROTEIN HOMOLOG 1, MITOCHONDRIAL enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;protein transmembrane import into intracellular organelle#GO:0044743;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000012203.4|UniProtKB=F7CE78 F7CE78 RO60 PTHR14202:SF0 60 KDA RIBONUCLEOPROTEIN SSA/RO RNA-BINDING PROTEIN RO60 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000009460.3|UniProtKB=F7FZI4 F7FZI4 AKAP5 PTHR15182:SF0 A-KINASE ANCHOR PROTEIN 5-RELATED A-KINASE ANCHOR PROTEIN 5 protein kinase A binding#GO:0051018;GABA receptor binding#GO:0050811;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;protein kinase A regulatory subunit binding#GO:0034237;enzyme binding#GO:0019899 membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;neuron projection membrane#GO:0032589;cell junction#GO:0030054;postsynapse#GO:0098794;dendritic spine#GO:0043197;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;dendrite#GO:0030425;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010934.5|UniProtKB=F7EPD3 F7EPD3 ULK2 PTHR24348:SF18 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE ULK2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cell development#GO:0048468;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;process utilizing autophagic mechanism#GO:0061919;neuron projection extension#GO:1990138;regulation of biological quality#GO:0065008;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;axon extension#GO:0048675;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;regulation of neuron projection development#GO:0010975;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;neuron projection development#GO:0031175;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of anatomical structure morphogenesis#GO:0022603;neuron differentiation#GO:0030182;growth#GO:0040007;regulation of anatomical structure size#GO:0090066;piecemeal microautophagy of the nucleus#GO:0034727;developmental cell growth#GO:0048588;regulation of cellular process#GO:0050794;negative regulation of multicellular organismal process#GO:0051241;regulation of neurogenesis#GO:0050767;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell development#GO:0060284;regulation of metabolic process#GO:0019222;neurogenesis#GO:0022008;regulation of catabolic process#GO:0009894;regulation of plasma membrane bounded cell projection organization#GO:0120035;mitophagy#GO:0000423;developmental growth#GO:0048589;neuron projection morphogenesis#GO:0048812;regulation of cell differentiation#GO:0045595;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular component size#GO:0032535;regulation of multicellular organismal development#GO:2000026;cellular component organization#GO:0016043;regulation of cell size#GO:0008361;developmental growth involved in morphogenesis#GO:0060560;generation of neurons#GO:0048699;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;regulation of cell growth#GO:0001558;autophagy#GO:0006914;response to stress#GO:0006950;cell projection morphogenesis#GO:0048858;regulation of axonogenesis#GO:0050770;cell growth#GO:0016049;plasma membrane bounded cell projection morphogenesis#GO:0120039;metabolic process#GO:0008152;regulation of developmental process#GO:0050793;catabolic process#GO:0009056;regulation of growth#GO:0040008;response to starvation#GO:0042594;negative regulation of cellular component organization#GO:0051129;system development#GO:0048731;vacuole organization#GO:0007033;regulation of nervous system development#GO:0051960;organelle assembly#GO:0070925;negative regulation of cell growth#GO:0030308;plasma membrane bounded cell projection organization#GO:0120036;macroautophagy#GO:0016236;response to nutrient levels#GO:0031667;reticulophagy#GO:0061709;axon development#GO:0061564;cellular developmental process#GO:0048869;developmental process#GO:0032502;autophagy of mitochondrion#GO:0000422 membrane#GO:0016020;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;autophagosome#GO:0005776;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000007231.4|UniProtKB=F6WBW3 F6WBW3 PTHR45881:SF3 CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED FORKHEAD BOX PROTEIN K2 MONDO|Ensembl=ENSMODG00000018764.3|UniProtKB=F7EKZ2 F7EKZ2 LOC100017398 PTHR23430:SF355 HISTONE H2A HISTONE H2A.J structural molecule activity#GO:0005198 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component assembly#GO:0022607;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000002605.4|UniProtKB=F7G4R1 F7G4R1 PTHR11037:SF13 TRANSCRIPTION FACTOR CP2 UPSTREAM-BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000023240.1|UniProtKB=F6UCT6 F6UCT6 KCNA10 PTHR11537:SF44 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 10 channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215 monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;action potential#GO:0001508;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;potassium ion transport#GO:0006813 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000003075.4|UniProtKB=A0A5F8GEE7 A0A5F8GEE7 TATDN3 PTHR46317:SF7 HYDROLASE OF PHP SUPERFAMILY-RELATED PROTEIN DEOXYRIBONUCLEASE TATDN3 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000020610.4|UniProtKB=A0A5F8GR96 A0A5F8GR96 PAPSS1 PTHR11055:SF17 BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;purine nucleotide biosynthetic process#GO:0006164;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;sulfur compound metabolic process#GO:0006790;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637 Sulfate assimilation#P02778>Sulfate adenylyltransferase#P03167 MONDO|Ensembl=ENSMODG00000041389.1|UniProtKB=A0A5F8GKI4 A0A5F8GKI4 PTHR22443:SF17 NON-SPECIFIC LETHAL 1, ISOFORM M KAT8 REGULATORY NSL COMPLEX SUBUNIT 1 S HOMEOLOG protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;NSL complex#GO:0044545;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000020870.4|UniProtKB=H9H7N8 H9H7N8 PTHR12902:SF9 WASP-1 WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER protein-containing complex binding#GO:0044877;protein binding#GO:0005515;protein kinase A regulatory subunit binding#GO:0034237;protein kinase A binding#GO:0051018;binding#GO:0005488 positive regulation of organelle organization#GO:0010638;actin filament-based process#GO:0030029;positive regulation of cellular component organization#GO:0051130;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 intracellular anatomical structure#GO:0005622;cell leading edge#GO:0031252;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000003369.3|UniProtKB=F6UHN1 F6UHN1 PTHR45720:SF3 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN CLC-KB voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;channel activity#GO:0015267;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836 monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000016705.4|UniProtKB=F7D2C8 F7D2C8 HRH3 PTHR24247:SF194 5-HYDROXYTRYPTAMINE RECEPTOR HISTAMINE H3 RECEPTOR molecular transducer activity#GO:0060089;postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;acetylcholine receptor activity#GO:0015464;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594 response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500 dendrite#GO:0030425;dendritic tree#GO:0097447;cell junction#GO:0030054;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 MONDO|Ensembl=ENSMODG00000007013.3|UniProtKB=F6XCH3 F6XCH3 MSMP PTHR10500:SF4 BETA-MICROSEMINOPROTEIN PROSTATE-ASSOCIATED MICROSEMINOPROTEIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000013511.3|UniProtKB=A0A5F8GNY1 A0A5F8GNY1 ARL2BP PTHR15487:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000039236.1|UniProtKB=A0A5F8HHM6 A0A5F8HHM6 PTHR10256:SF1 SELENIDE, WATER DIKINASE SELENIDE, WATER DIKINASE 2 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000016943.4|UniProtKB=A0A5F8GVS8 A0A5F8GVS8 ZNF654 PTHR15507:SF16 ZINC FINGER PROTEIN RLF ZINC FINGER PROTEIN 654 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000046138.1|UniProtKB=A0A5F8GYN2 A0A5F8GYN2 PTHR11437:SF24 RIBONUCLEASE RIBONUCLEASE PANCREATIC nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 defense response#GO:0006952;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to Gram-positive bacterium#GO:0050830 endoribonuclease#PC00094;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000048348.1|UniProtKB=A0A5F8H0B5 A0A5F8H0B5 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000003802.4|UniProtKB=A0A5F8H4I5 A0A5F8H4I5 NOL6 PTHR17972:SF0 NUCLEOLAR RNA-ASSOCIATED PROTEIN NUCLEOLAR PROTEIN 6 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;small-subunit processome#GO:0032040;90S preribosome#GO:0030686;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000041615.1|UniProtKB=A0A5F8G8D4 A0A5F8G8D4 PTHR19339:SF5 T CELL RECEPTOR ALPHA VARIABLE 39 IG-LIKE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000006460.4|UniProtKB=F7FGR7 F7FGR7 KLK15 PTHR24271:SF60 KALLIKREIN-RELATED KALLIKREIN-15 catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000010662.4|UniProtKB=F7CKH2 F7CKH2 ASPHD2 PTHR46332:SF3 ASPARTATE BETA-HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2 ASPARTATE BETA-HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2 oxidoreductase#PC00176;hydroxylase#PC00122 MONDO|Ensembl=ENSMODG00000008358.4|UniProtKB=F7EJN7 F7EJN7 SLC15A1 PTHR11654:SF89 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;dipeptide transmembrane transporter activity#GO:0071916;oligopeptide transmembrane transporter activity#GO:0035673 peptide transport#GO:0015833;nitrogen compound transport#GO:0071705;oligopeptide transmembrane transport#GO:0035672;cellular process#GO:0009987;import across plasma membrane#GO:0098739;transport#GO:0006810;localization#GO:0051179;dipeptide transport#GO:0042938;import into cell#GO:0098657;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;oligopeptide transport#GO:0006857 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transporter#PC00227 MONDO|Ensembl=ENSMODG00000001304.4|UniProtKB=A0A5F8GG66 A0A5F8GG66 LOC100016303 PTHR24024:SF15 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A PULMONARY SURFACTANT-ASSOCIATED PROTEIN D molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023 positive regulation of cellular process#GO:0048522;immune response#GO:0006955;complement activation#GO:0006956;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of endocytosis#GO:0045807;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;activation of immune response#GO:0002253;positive regulation of transport#GO:0051050;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;immune effector process#GO:0002252;regulation of endocytosis#GO:0030100;humoral immune response#GO:0006959;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;positive regulation of cellular component organization#GO:0051130;immune system process#GO:0002376 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 surfactant#PC00212;structural protein#PC00211 MONDO|Ensembl=ENSMODG00000001594.4|UniProtKB=A0A5F8G463 A0A5F8G463 CYRIB PTHR12422:SF7 GH09096P CYFIP RELATED RAC1 INTERACTOR B positive regulation of leukocyte activation#GO:0002696;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of cell activation#GO:0050867;regulation of multicellular organismal process#GO:0051239;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;regulation of T cell activation#GO:0050863;positive regulation of T cell activation#GO:0050870;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of lymphocyte activation#GO:0051251;regulation of lymphocyte activation#GO:0051249;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;positive regulation of cell adhesion#GO:0045785;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694 MONDO|Ensembl=ENSMODG00000021016.4|UniProtKB=F6QZE3 F6QZE3 ABCG1 PTHR48041:SF90 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 1 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626 homeostatic process#GO:0042592;lipid homeostasis#GO:0055088;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;transmembrane transport#GO:0055085;lipid localization#GO:0010876;lipid transport#GO:0006869;cholesterol efflux#GO:0033344;cellular process#GO:0009987;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;establishment of localization#GO:0051234;cholesterol homeostasis#GO:0042632;sterol transport#GO:0015918;transport#GO:0006810;chemical homeostasis#GO:0048878 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000009995.4|UniProtKB=F6USD6 F6USD6 RFXAP PTHR15110:SF2 REGULATORY FACTOR X-ASSOCIATED PROTEIN REGULATORY FACTOR X-ASSOCIATED PROTEIN regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000043051.1|UniProtKB=A0A5F8H9U4 A0A5F8H9U4 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000017122.4|UniProtKB=A0A5F8GBP0 A0A5F8GBP0 PTHR11782:SF117 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 8 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110;ribonucleoside triphosphate phosphatase activity#GO:0017111 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside diphosphate catabolic process#GO:0009134;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside diphosphate metabolic process#GO:0009132;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 hydrolase#PC00121;nucleotide phosphatase#PC00173;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000004443.3|UniProtKB=F6RSZ7 F6RSZ7 PTHR48112:SF12 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP BOX 1, PSEUDOGENE 34 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 p53 pathway#P00059>HMG1#P04619 MONDO|Ensembl=ENSMODG00000005727.6|UniProtKB=F6TMZ7 F6TMZ7 PDE4A PTHR11347:SF74 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 4A cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 hydrolase#PC00121;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000004946.4|UniProtKB=F7ATM1 F7ATM1 AP1S1 PTHR11753:SF14 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-1 COMPLEX SUBUNIT SIGMA-1A establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000008067.4|UniProtKB=F6YK89 F6YK89 CPNE3 PTHR10857:SF22 COPINE COPINE-3 phospholipid binding#GO:0005543;receptor tyrosine kinase binding#GO:0030971;kinase binding#GO:0019900;binding#GO:0005488;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515;lipid binding#GO:0008289 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to calcium ion#GO:0051592;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to chemical stimulus#GO:0070887;biological regulation#GO:0065007;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;response to metal ion#GO:0010038;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000005671.4|UniProtKB=A0A5F8GTV2 A0A5F8GTV2 MTM1 PTHR10807:SF69 MYOTUBULARIN-RELATED MYOTUBULARIN hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 mitochondrion localization#GO:0051646;regulation of catabolic process#GO:0009894;cellular homeostasis#GO:0019725;negative regulation of autophagy#GO:0010507;lipid modification#GO:0030258;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;regulation of metabolic process#GO:0019222;organophosphate metabolic process#GO:0019637;negative regulation of catabolic process#GO:0009895;localization#GO:0051179;dephosphorylation#GO:0016311;phosphatidylinositol dephosphorylation#GO:0046856;organelle localization#GO:0051640;homeostatic process#GO:0042592;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;phospholipid dephosphorylation#GO:0046839;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;primary metabolic process#GO:0044238;regulation of macroautophagy#GO:0016241;metabolic process#GO:0008152;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;negative regulation of macroautophagy#GO:0016242;regulation of autophagosome assembly#GO:2000785;regulation of cellular component biogenesis#GO:0044087;negative regulation of metabolic process#GO:0009892;regulation of cellular component organization#GO:0051128;glycerolipid metabolic process#GO:0046486;phosphate-containing compound metabolic process#GO:0006796;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519 membrane#GO:0016020;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000020859.2|UniProtKB=F6R091 F6R091 PTHR16565:SF2 APOLIPOPROTEIN C-I APOLIPOPROTEIN C-I molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;fatty acid binding#GO:0005504;lipid binding#GO:0008289;molecular function inhibitor activity#GO:0140678;ion binding#GO:0043167;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;organic acid binding#GO:0043177 acylglycerol metabolic process#GO:0006639;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;plasma lipoprotein particle clearance#GO:0034381;neutral lipid metabolic process#GO:0006638;regulation of catabolic process#GO:0009894;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of lipid metabolic process#GO:0019216;negative regulation of catabolic process#GO:0009895;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of lipid catabolic process#GO:0050994;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;glycerolipid metabolic process#GO:0046486;negative regulation of metabolic process#GO:0009892 lipoprotein particle#GO:1990777;extracellular protein-containing complex#GO:0140392;protein-lipid complex#GO:0032994;extracellular region#GO:0005576;high-density lipoprotein particle#GO:0034364;plasma lipoprotein particle#GO:0034358;very-low-density lipoprotein particle#GO:0034361;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 apolipoprotein#PC00052;transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000019157.4|UniProtKB=F7BK46 F7BK46 PTHR12015:SF147 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 13 chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379 cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;response to peptide#GO:1901652;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of cell motility#GO:2000147;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;taxis#GO:0042330;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cytokine-mediated signaling pathway#GO:0019221;cell chemotaxis#GO:0060326;regulation of cell motility#GO:2000145;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cellular response to stimulus#GO:0051716;response to external biotic stimulus#GO:0043207;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cell migration#GO:0030334;leukocyte migration#GO:0050900;myeloid leukocyte migration#GO:0097529;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;cell migration#GO:0016477 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000048184.1|UniProtKB=F6PYR1 F6PYR1 LOC100020167 PTHR26450:SF411 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51A7 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038188.1|UniProtKB=F6S0W1 F6S0W1 PTHR23226:SF425 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 24 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000027416.2|UniProtKB=K7E3P3 K7E3P3 PTHR10671:SF42 EPITHELIAL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 202 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000007783.4|UniProtKB=F7AW70 F7AW70 SYNJ2 PTHR11200:SF148 INOSITOL 5-PHOSPHATASE POLYPHOSPHATIDYLINOSITOL PHOSPHATASE SYNJ2 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic vesicle endocytosis#GO:0048488;endocytosis#GO:0006897;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular localization#GO:0051641 intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165;synapse#GO:0045202;presynapse#GO:0098793;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000020591.4|UniProtKB=F7A0P1 F7A0P1 YIPF7 PTHR21236:SF5 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF7 endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle fusion#GO:0006906;Golgi organization#GO:0007030;cellular component organization#GO:0016043;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000004105.5|UniProtKB=F6VEY3 F6VEY3 MEF2B PTHR11945:SF383 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2B transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;histone deacetylase binding#GO:0042826;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;heart development#GO:0007507;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MADS box transcription factor#PC00250 p38 MAPK pathway#P05918>MEF#P06023;CCKR signaling map#P06959>MEF2B#P07075 MONDO|Ensembl=ENSMODG00000021108.4|UniProtKB=F6U2Z1 F6U2Z1 SYTL5 PTHR45716:SF6 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 5 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 exocytosis#GO:0006887;secretion by cell#GO:0032940;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000013043.4|UniProtKB=F7G168 F7G168 MYOM3 PTHR13817:SF89 TITIN MYOMESIN-3 structural molecule activity#GO:0005198 striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;anatomical structure morphogenesis#GO:0009653;muscle cell development#GO:0055001;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 A band#GO:0031672;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;M band#GO:0031430;intracellular organelle#GO:0043229;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000012379.3|UniProtKB=F6PQ98 F6PQ98 LRRC38 PTHR46473:SF4 GH08155P LEUCINE-RICH REPEAT-CONTAINING PROTEIN 38 voltage-gated monoatomic ion channel activity#GO:0005244;binding#GO:0005488;gated channel activity#GO:0022836;potassium channel regulator activity#GO:0015459;voltage-gated potassium channel activity#GO:0005249;protein binding#GO:0005515;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;molecular function activator activity#GO:0140677;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;potassium channel activity#GO:0005267;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796 MONDO|Ensembl=ENSMODG00000024755.2|UniProtKB=F7GK66 F7GK66 G0S2 PTHR15570:SF2 G0/G1 SWITCH PROTEIN 2 G0_G1 SWITCH PROTEIN 2 cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;apoptotic signaling pathway#GO:0097190;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;positive regulation of programmed cell death#GO:0043068;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of apoptotic process#GO:0043065 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000046969.1|UniProtKB=A0A5F8H310 A0A5F8H310 PTHR23226:SF425 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 24 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015034.5|UniProtKB=A0A5F8HLV2 A0A5F8HLV2 CAMSAP3 PTHR21595:SF2 PATRONIN CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 3 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;negative regulation of protein depolymerization#GO:1901880;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cytoplasmic microtubule organization#GO:0031122;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule-based process#GO:0032886;negative regulation of protein-containing complex disassembly#GO:0043242;microtubule cytoskeleton organization#GO:0000226;negative regulation of cytoskeleton organization#GO:0051494;supramolecular fiber organization#GO:0097435 microtubule cytoskeleton#GO:0015630;microtubule end#GO:1990752;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 MONDO|Ensembl=ENSMODG00000002719.4|UniProtKB=A0A5F8GVX4 A0A5F8GVX4 SLC12A1 PTHR11827:SF93 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 1 metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;chloride transport#GO:0006821;establishment of localization#GO:0051234;sodium ion transport#GO:0006814;monoatomic anion transport#GO:0006820;metal ion transport#GO:0030001;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000048101.1|UniProtKB=A0A5F8G7Y1 A0A5F8G7Y1 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020658.4|UniProtKB=F7E5X5 F7E5X5 LOC100014151 PTHR31102:SF1 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 9 MEMBER B2 MONDO|Ensembl=ENSMODG00000008613.4|UniProtKB=F7F1L8 F7F1L8 TEAD1 PTHR11834:SF4 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED TRANSCRIPTIONAL ENHANCER FACTOR TEF-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;embryo development#GO:0009790;hippo signaling#GO:0035329;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;animal gross anatomical part developmental process#GO:0160108;embryonic organ development#GO:0048568;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000009661.4|UniProtKB=A0A5F8H0V8 A0A5F8H0V8 CORO6 PTHR10856:SF23 CORONIN CORONIN-6 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cell motility#GO:0048870;cell migration#GO:0016477;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 actin cytoskeleton#GO:0015629;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;lamellipodium#GO:0030027;supramolecular polymer#GO:0099081;actin filament#GO:0005884;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000020708.4|UniProtKB=F7BAY4 F7BAY4 TRMT10A PTHR13563:SF20 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG A binding#GO:0005488;nucleic acid binding#GO:0003676;tRNA binding#GO:0000049;RNA binding#GO:0003723 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA methylation#GO:0030488;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000003768.4|UniProtKB=F7DJN6 F7DJN6 DHRS2 PTHR43943:SF15 DEHYDROGENASE/REDUCTASE (SDR FAMILY) MEMBER 4 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 4 catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000006441.4|UniProtKB=A0A5F8G564 A0A5F8G564 PTHR23119:SF6 DISCS LARGE DISKS LARGE HOMOLOG 2 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;signaling receptor binding#GO:0005102 receptor clustering#GO:0043113;cell adhesion#GO:0007155;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657;signaling#GO:0023052;protein localization to synapse#GO:0035418;multicellular organism development#GO:0007275;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;nervous system development#GO:0007399;localization within membrane#GO:0051668;establishment or maintenance of bipolar cell polarity#GO:0061245;protein localization to cell junction#GO:1902414;establishment or maintenance of apical/basal cell polarity#GO:0035088;trans-synaptic signaling#GO:0099537;system development#GO:0048731;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;cell communication#GO:0007154;localization#GO:0051179;anatomical structure development#GO:0048856;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;developmental process#GO:0032502;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;cell junction#GO:0030054;neuromuscular junction#GO:0031594 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000041329.1|UniProtKB=A0A5F8GCI8 A0A5F8GCI8 PTHR13680:SF33 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 2 iron-sulfur cluster binding#GO:0051536;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transaminase activity#GO:0008483 inorganic ion homeostasis#GO:0098771;process utilizing autophagic mechanism#GO:0061919;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;catabolic process#GO:0009056;intracellular iron ion homeostasis#GO:0006879;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;autophagy#GO:0006914;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968 MONDO|Ensembl=ENSMODG00000024030.1|UniProtKB=F7DMS4 F7DMS4 ATP6V1G3 PTHR12713:SF5 VACUOLAR ATP SYNTHASE SUBUNIT G V-TYPE PROTON ATPASE SUBUNIT G 3 cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;homeostatic process#GO:0042592;cellular component organization#GO:0016043;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;proton transmembrane transport#GO:1902600;synaptic vesicle maturation#GO:0016188;cellular component organization or biogenesis#GO:0071840;cellular homeostasis#GO:0019725;vesicle organization#GO:0016050;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;developmental process#GO:0032502;vesicle-mediated transport#GO:0016192;developmental maturation#GO:0021700;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 ATPase dependent transmembrane transport complex#GO:0098533;exocytic vesicle#GO:0070382;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;transporter complex#GO:1990351;cell junction#GO:0030054;proton-transporting two-sector ATPase complex#GO:0016469;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular membrane-bounded organelle#GO:0043231;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;synaptic vesicle#GO:0008021;cation-transporting ATPase complex#GO:0090533;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;vacuolar membrane#GO:0005774;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000002884.4|UniProtKB=F7B649 F7B649 POLR1E PTHR14440:SF7 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;transcription initiation at RNA polymerase I promoter#GO:0006361;DNA-templated transcription elongation#GO:0006354;transcription by RNA polymerase I#GO:0006360;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139 intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase I complex#GO:0005736;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233 DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000000555.3|UniProtKB=A0A5F8HCR1 A0A5F8HCR1 DPP10 PTHR11731:SF21 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED INACTIVE DIPEPTIDYL PEPTIDASE 10 potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;peptidase activity#GO:0008233 metabolic process#GO:0008152;regulation of monoatomic cation transmembrane transport#GO:1904062;macromolecule metabolic process#GO:0043170;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;proteolysis#GO:0006508;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000028686.2|UniProtKB=K7E3Z9 K7E3Z9 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000024929.2|UniProtKB=F6RB09 F6RB09 MOS PTHR23257:SF706 SERINE-THREONINE PROTEIN KINASE PROTO-ONCOGENE SERINE_THREONINE-PROTEIN KINASE MOS kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096 negative regulation of cell cycle#GO:0045786;negative regulation of chromosome segregation#GO:0051985;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;regulation of chromosome segregation#GO:0051983;regulation of MAPK cascade#GO:0043408;regulation of chromosome separation#GO:1905818;regulation of cell cycle process#GO:0010564;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;regulation of organelle organization#GO:0033043;positive regulation of MAPK cascade#GO:0043410;negative regulation of chromosome separation#GO:1905819;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cell cycle process#GO:0010948;regulation of response to stimulus#GO:0048583;regulation of reproductive process#GO:2000241;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000004832.3|UniProtKB=F6ULC4 F6ULC4 WFDC1 PTHR14308:SF0 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of cell growth#GO:0001558;regulation of cellular process#GO:0050794;regulation of growth#GO:0040008;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000009023.3|UniProtKB=F7B328 F7B328 TMEM184A PTHR23423:SF59 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184A transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;early endosome membrane#GO:0031901 transporter#PC00227 MONDO|Ensembl=ENSMODG00000001964.4|UniProtKB=F6V2A6 F6V2A6 SENP7 PTHR46896:SF2 SENTRIN-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 7 ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000014549.4|UniProtKB=F7E8X5 F7E8X5 RDX PTHR23281:SF14 MERLIN/MOESIN/EZRIN/RADIXIN RADIXIN protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of anatomical structure morphogenesis#GO:0022603;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of cellular component biogenesis#GO:0044087;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;filopodium#GO:0030175;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin-based cell projection#GO:0098858;microvillus#GO:0005902;actin cytoskeleton#GO:0015629;adherens junction#GO:0005912;cell junction#GO:0030054;membraneless organelle#GO:0043228;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000013782.4|UniProtKB=F6TUW7 F6TUW7 PTHR21590:SF4 SEA DOMAIN-CONTAINING PROTEIN UPF0606 PROTEIN KIAA1549 MONDO|Ensembl=ENSMODG00000009637.3|UniProtKB=F6QTS7 F6QTS7 SLC39A12 PTHR12191:SF4 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP12 monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;transition metal ion transmembrane transporter activity#GO:0046915;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;zinc ion transmembrane transporter activity#GO:0005385;bicarbonate transmembrane transporter activity#GO:0015106 monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular monoatomic ion homeostasis#GO:0006873;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000020424.3|UniProtKB=F7ARQ5 F7ARQ5 LMAN1 PTHR12223:SF28 VESICULAR MANNOSE-BINDING LECTIN LECTIN, MANNOSE BINDING 1 LIKE monosaccharide binding#GO:0048029;carbohydrate binding#GO:0030246;small molecule binding#GO:0036094;binding#GO:0005488 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000037394.1|UniProtKB=A0A5F8GB06 A0A5F8GB06 KCNA7 PTHR11537:SF155 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 7 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836 action potential#GO:0001508;metal ion transport#GO:0030001;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 voltage-gated ion channel#PC00241;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000014596.2|UniProtKB=F7A3Z4 F7A3Z4 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 immune system process#GO:0002376;immune effector process#GO:0002252;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000016353.4|UniProtKB=F7F6U5 F7F6U5 SLC26A4 PTHR11814:SF33 SULFATE TRANSPORTER PENDRIN carboxylic acid transmembrane transporter activity#GO:0046943;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;dicarboxylic acid transmembrane transporter activity#GO:0005310;active transmembrane transporter activity#GO:0022804 chloride transport#GO:0006821;transport#GO:0006810;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000008946.5|UniProtKB=F7GD13 F7GD13 PTF1A PTHR23349:SF59 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST PANCREAS TRANSCRIPTION FACTOR 1 SUBUNIT ALPHA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000024007.2|UniProtKB=F6VMC8 F6VMC8 PTHR15208:SF2 RECEPTOR-BINDING CANCER ANTIGEN EXPRESSED ON SISO CELLS CANCER ASSOCIATED SURFACE ANTIGEN RCAS1 ESTROGEN RECEPTOR-BINDING FRAGMENT- ASSOCIATED GENE 9 PROTEIN RECEPTOR-BINDING CANCER ANTIGEN EXPRESSED ON SISO CELLS molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of secretion#GO:0051046;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627 secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141 MONDO|Ensembl=ENSMODG00000014703.4|UniProtKB=F7D3K9 F7D3K9 CPSF3 PTHR11203:SF11 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3 exonuclease activity#GO:0004527;nucleic acid binding#GO:0003676;binding#GO:0005488;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000013474.5|UniProtKB=F7FMK4 F7FMK4 KMT2A PTHR45838:SF2 HISTONE-LYSINE-N-METHYLTRANSFERASE 2 KMT2 FAMILY MEMBER HISTONE-LYSINE N-METHYLTRANSFERASE 2A lysine N-methyltransferase activity#GO:0016278;histone H3K4 methyltransferase activity#GO:0042800;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000039729.1|UniProtKB=K7E3M9 K7E3M9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000042660.1|UniProtKB=A0A5F8HGQ1 A0A5F8HGQ1 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000010983.3|UniProtKB=F7API9 F7API9 MFSD3 PTHR12778:SF10 SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED SOLUTE CARRIER FAMILY 33 MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000006024.3|UniProtKB=F7AJ24 F7AJ24 SLC7A13 PTHR11785:SF348 AMINO ACID TRANSPORTER SOLUTE CARRIER FAMILY 7 MEMBER 12 L-amino acid transmembrane transporter activity#GO:0015179;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;transport#GO:0006810;cellular process#GO:0009987;amino acid transport#GO:0006865 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 MONDO|Ensembl=ENSMODG00000008755.4|UniProtKB=F6PRT3 F6PRT3 INTS9 PTHR46094:SF1 INTEGRATOR COMPLEX SUBUNIT 9 INTEGRATOR COMPLEX SUBUNIT 9 RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;integrator complex#GO:0032039;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000013718.5|UniProtKB=F6XRP6 F6XRP6 FLII PTHR11977:SF142 VILLIN PROTEIN FLIGHTLESS-1 HOMOLOG protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543 cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of anatomical structure size#GO:0090066;cellular anatomical entity morphogenesis#GO:0032989;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;striated muscle cell development#GO:0055002;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;regulation of actin filament length#GO:0030832;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;negative regulation of actin filament polymerization#GO:0030837;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;actin polymerization or depolymerization#GO:0008154;anatomical structure development#GO:0048856;negative regulation of protein-containing complex assembly#GO:0031333;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;regulation of actin filament depolymerization#GO:0030834;negative regulation of organelle organization#GO:0010639;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of protein-containing complex disassembly#GO:0043244;negative regulation of actin filament depolymerization#GO:0030835;cell differentiation#GO:0030154;actomyosin structure organization#GO:0031032;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component size#GO:0032535;cellular developmental process#GO:0048869;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament organization#GO:0110053;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;actin filament capping#GO:0051693;actin cytoskeleton organization#GO:0030036;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;myofibril assembly#GO:0030239 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;nucleus#GO:0005634 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000038028.1|UniProtKB=A0A5F8GQK9 A0A5F8GQK9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008710.4|UniProtKB=A0A5F8GAD9 A0A5F8GAD9 FLNA PTHR38537:SF5 JITTERBUG, ISOFORM N FILAMIN-A Integrin signalling pathway#P00034>Filamin#P00914;Nicotine pharmacodynamics pathway#P06587>FLNA#P06601;Dopamine receptor mediated signaling pathway#P05912>FLNA#P05959 MONDO|Ensembl=ENSMODG00000002882.3|UniProtKB=F7B657 F7B657 CCT4 PTHR11353:SF26 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT DELTA protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytosol#GO:0005829;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832 chaperonin#PC00073 MONDO|Ensembl=ENSMODG00000011148.4|UniProtKB=F7ANP9 F7ANP9 ANGPTL7 PTHR19143:SF40 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 7 sensory system development#GO:0048880;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;sensory organ development#GO:0007423;regulation of vasculature development#GO:1901342;developmental process#GO:0032502;multicellular organism development#GO:0007275;animal organ development#GO:0048513;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;visual system development#GO:0150063;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000009719.5|UniProtKB=F6XSP0 F6XSP0 STAM PTHR45929:SF2 JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE SIGNAL TRANSDUCING ADAPTER MOLECULE 1 establishment of protein localization to vacuole#GO:0072666;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;cellular localization#GO:0051641;protein transport#GO:0015031;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endosomal transport#GO:0016197;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular protein transport#GO:0006886;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;localization#GO:0051179;protein metabolic process#GO:0019538;protein localization to vacuole#GO:0072665;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;macromolecule localization#GO:0033036;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000008326.4|UniProtKB=F7F307 F7F307 COPG1 PTHR10261:SF3 COATOMER SUBUNIT GAMMA COATOMER SUBUNIT GAMMA-1 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810 endoplasmic reticulum#GO:0005783;Golgi-associated vesicle#GO:0005798;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle coat#GO:0030120;cytoplasm#GO:0005737;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;coated membrane#GO:0048475;membrane coat#GO:0030117;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165 vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000039409.1|UniProtKB=K7E0Q6 K7E0Q6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000016155.3|UniProtKB=F7D6E6 F7D6E6 PTHR26453:SF13 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002983.4|UniProtKB=A0A5F8GQ02 A0A5F8GQ02 SPPL3 PTHR12174:SF22 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 3 aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;Golgi-associated vesicle membrane#GO:0030660;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;side of membrane#GO:0098552;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;endoplasmic reticulum#GO:0005783;cytoplasmic side of membrane#GO:0098562;endoplasmic reticulum membrane#GO:0005789;Golgi-associated vesicle#GO:0005798;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 protein modifying enzyme#PC00260;aspartic protease#PC00053 MONDO|Ensembl=ENSMODG00000010129.3|UniProtKB=A0A5F8G7Z6 A0A5F8G7Z6 CROT PTHR22589:SF67 CARNITINE O-ACYLTRANSFERASE PEROXISOMAL CARNITINE O-OCTANOYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000021034.4|UniProtKB=F7DKA9 F7DKA9 PDXK PTHR10534:SF2 PYRIDOXAL KINASE PYRIDOXAL KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;pyridine-containing compound metabolic process#GO:0072524;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137 Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine kinase#P03122;Vitamin B6 metabolism#P02787>Pyridoxal kinase#P03244;Pyridoxal phosphate salvage pathway#P02770>Pyridoxal kinase#P03121 MONDO|Ensembl=ENSMODG00000020994.4|UniProtKB=F6RKK2 F6RKK2 USP16 PTHR21646:SF12 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 16 catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of protein stability#GO:0031647;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000047627.1|UniProtKB=F7F2W3 F7F2W3 KYAT1 PTHR43807:SF14 FI04487P KYNURENINE--OXOGLUTARATE TRANSAMINASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transaminase activity#GO:0008483 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transferase#PC00220;transaminase#PC00216;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000004975.3|UniProtKB=F7FKZ7 F7FKZ7 INO80B PTHR21561:SF12 INO80 COMPLEX SUBUNIT B INO80 COMPLEX SUBUNIT B Ino80 complex#GO:0031011;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000046184.1|UniProtKB=F7DUP6 F7DUP6 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED RETROVIRAL ENVELOPE PROTEIN GP41-LIKE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000006050.5|UniProtKB=F7FSK2 F7FSK2 MAPK8IP2 PTHR47437:SF2 JNK-INTERACTING PROTEIN 1-LIKE PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 2 signaling adaptor activity#GO:0035591;protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;MAP kinase scaffold activity#GO:0005078;structural molecule activity#GO:0005198;molecular adaptor activity#GO:0060090;protein complex scaffold activity#GO:0140378 JNK cascade#GO:0007254;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000045792.1|UniProtKB=A0A5F8HFC8 A0A5F8HFC8 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000050494.1|UniProtKB=K7E475 K7E475 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000045581.1|UniProtKB=A0A5F8GQA5 A0A5F8GQA5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008223.4|UniProtKB=A0A5F8GCS4 A0A5F8GCS4 ZNF280D PTHR24388:SF34 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 280D DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000023930.1|UniProtKB=F7FLF3 F7FLF3 TMEM229B PTHR31746:SF3 TRANSMEMBRANE PROTEIN 229 FAMILY MEMBER TRANSMEMBRANE PROTEIN 229B MONDO|Ensembl=ENSMODG00000028786.2|UniProtKB=A0A5F8HAB5 A0A5F8HAB5 PTHR24103:SF564 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN LIGASE TRIM40 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000017024.4|UniProtKB=F6Y0W5 F6Y0W5 DAP3 PTHR12810:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S29 SMALL RIBOSOMAL SUBUNIT PROTEIN MS29 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000024849.1|UniProtKB=F7EBU3 F7EBU3 KCNA5 PTHR11537:SF250 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 5 voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 metal ion transport#GO:0030001;action potential#GO:0001508;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810 anchoring junction#GO:0070161;intercalated disc#GO:0014704;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;cell-cell contact zone#GO:0044291;cell junction#GO:0030054;transporter complex#GO:1990351;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000024666.3|UniProtKB=F7B407 F7B407 C2orf88 PTHR36471:SF1 SMALL MEMBRANE A-KINASE ANCHOR PROTEIN A-KINASE ANCHORING PROTEIN 19 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000002089.4|UniProtKB=A0A5F8GBI0 A0A5F8GBI0 RBFOX3 PTHR15597:SF25 ATAXIN 2-BINDING PROTEIN 1-RELATED RNA BINDING PROTEIN FOX-1 HOMOLOG 3 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;multicellular organismal process#GO:0032501;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000043880.1|UniProtKB=A0A5F8GNY3 A0A5F8GNY3 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000041965.1|UniProtKB=A0A5F8G4J7 A0A5F8G4J7 PTHR16675:SF67 MHC CLASS I-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000000182.3|UniProtKB=F6TG05 F6TG05 AMZ1 PTHR32205:SF4 ARCHAEMETZINCIN-2-RELATED ARCHAEMETZINCIN-1 MONDO|Ensembl=ENSMODG00000051313.1|UniProtKB=A0A5F8GPY2 A0A5F8GPY2 PTHR11880:SF2 RIBOSOMAL PROTEIN S19P FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US19 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000038311.1|UniProtKB=A0A5F8HLN5 A0A5F8HLN5 HRAS PTHR24070:SF385 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE HRAS hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;Ras protein signal transduction#GO:0007265;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 Ras Pathway#P04393>Ras#P04547;EGF receptor signaling pathway#P00018>Ras#P00552;TGF-beta signaling pathway#P00052>Ras-GDP#P01291;PDGF signaling pathway#P00047>Ras#P01154;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;VEGF signaling pathway#P00056>Ras#P01411;Integrin signalling pathway#P00034>Ras#P00916;Angiogenesis#P00005>Ras#P00238;B cell activation#P00010>Ras#P00376;PI3 kinase pathway#P00048>Ras#P01182;T cell activation#P00053>Ras#P01306;FGF signaling pathway#P00021>Ras#P00633;p53 pathway feedback loops 2#P04398>Ras#P04651 MONDO|Ensembl=ENSMODG00000001704.4|UniProtKB=A0A5F8HC10 A0A5F8HC10 PTHR10956:SF0 60S RIBOSOMAL PROTEIN L31 LARGE RIBOSOMAL SUBUNIT PROTEIN EL31 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000011803.5|UniProtKB=F7CBK5 F7CBK5 MPHOSPH10 PTHR17039:SF0 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;90S preribosome#GO:0030686;small-subunit processome#GO:0032040;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000000339.3|UniProtKB=A0A5F8GXV8 A0A5F8GXV8 EML4 PTHR13720:SF11 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 4 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000006515.4|UniProtKB=F7E3Z9 F7E3Z9 HNRNPU PTHR12381:SF11 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;RNA binding#GO:0003723 RNA splicing, via transesterification reactions#GO:0000375;positive regulation of biosynthetic process#GO:0009891;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;mRNA metabolic process#GO:0016071;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA processing#GO:0006397;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;RNA processing#GO:0006396 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000010095.2|UniProtKB=F6XLM8 F6XLM8 FAU PTHR12650:SF37 40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI 40S RIBOSOMAL PROTEIN S30 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000027692.2|UniProtKB=K7DZA6 K7DZA6 MEIKIN PTHR38006:SF1 MEIOSIS-SPECIFIC KINETOCHORE PROTEIN MEIOSIS-SPECIFIC KINETOCHORE PROTEIN organelle organization#GO:0006996;cellular process#GO:0009987;male gamete generation#GO:0048232;male meiotic nuclear division#GO:0007140;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;meiotic sister chromatid cohesion#GO:0051177;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;cell cycle#GO:0007049;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;cell cycle process#GO:0022402;gamete generation#GO:0007276;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;sexual reproduction#GO:0019953;sister chromatid cohesion#GO:0007062;organelle fission#GO:0048285;multicellular organismal reproductive process#GO:0048609 MONDO|Ensembl=ENSMODG00000040103.1|UniProtKB=A0A5F8GST1 A0A5F8GST1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000851.4|UniProtKB=F7BI98 F7BI98 KLF5 PTHR18950:SF2 PROGESTERONE-INDUCED BLOCKING FACTOR 1 KLF TRANSCRIPTION FACTOR 5 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987 intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000014528.3|UniProtKB=F7ER49 F7ER49 LOC100616785 PTHR47084:SF1 SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT A SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT A catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 ceramide metabolic process#GO:0006672;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987 protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000018214.4|UniProtKB=F7FP57 F7FP57 GSG1 PTHR10671:SF43 EPITHELIAL MEMBRANE PROTEIN-RELATED GERM CELL-SPECIFIC GENE 1 PROTEIN intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000011628.3|UniProtKB=F6U132 F6U132 PTHR12391:SF10 ARP2/3 COMPLEX 21 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036 Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 MONDO|Ensembl=ENSMODG00000040535.1|UniProtKB=F6ZZ56 F6ZZ56 LOC100021392 PTHR26450:SF19 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017141.4|UniProtKB=F6TM73 F6TM73 PTHR10742:SF355 FLAVIN MONOAMINE OXIDASE AMINE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056 oxidase#PC00175 5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 MONDO|Ensembl=ENSMODG00000011288.4|UniProtKB=F6WZG5 F6WZG5 CDCP1 PTHR14477:SF1 CUB DOMAIN-CONTAINING PROTEIN 1 CUB DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000018778.4|UniProtKB=A0A5F8GTT5 A0A5F8GTT5 APH1A PTHR12889:SF3 GAMMA-SECRETASE SUBUNIT APH-1 GAMMA-SECRETASE SUBUNIT APH-1A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein metabolic process#GO:0019538;cell communication#GO:0007154;proteolysis#GO:0006508;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;Notch signaling pathway#GO:0007219;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;biological regulation#GO:0065007;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;signal transduction#GO:0007165 catalytic complex#GO:1902494;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 protein modifying enzyme#PC00260;protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>Aph-1#P00091;Notch signaling pathway#P00045>Aph-1#P01109;Alzheimer disease-presenilin pathway#P00004>Aph-1#P00170 MONDO|Ensembl=ENSMODG00000046812.1|UniProtKB=A0A5F8G770 A0A5F8G770 NPFFR1 PTHR24241:SF4 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE FF RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007;response to endogenous stimulus#GO:0009719;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000003401.5|UniProtKB=F6Z0D5 F6Z0D5 DMRT1 PTHR12322:SF70 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;sex differentiation#GO:0007548;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000011442.5|UniProtKB=F6W1L3 F6W1L3 GPATCH8 PTHR17614:SF11 ZINC FINGER-CONTAINING G PATCH DOMAIN-CONTAINING PROTEIN 8 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000010829.4|UniProtKB=A0A5F8GJT3 A0A5F8GJT3 KPNA3 PTHR23316:SF6 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-4 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;cellular localization#GO:0051641 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000021362.4|UniProtKB=A0A5F8HH14 A0A5F8HH14 TMEM59 PTHR28652:SF3 TRANSMEMBRANE PROTEIN 59-LIKE PROTEIN TRANSMEMBRANE PROTEIN 59 positive regulation of catabolic process#GO:0009896;positive regulation of metabolic process#GO:0009893;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of autophagy#GO:0010506;positive regulation of autophagy#GO:0010508;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 late endosome#GO:0005770;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737;lytic vacuole#GO:0000323;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 MONDO|Ensembl=ENSMODG00000013720.4|UniProtKB=A0A5F8HE54 A0A5F8HE54 RNF214 PTHR15727:SF3 RING FINGER PROTEIN 214 RING FINGER PROTEIN 214 catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 MONDO|Ensembl=ENSMODG00000015320.3|UniProtKB=A0A5F8G6E0 A0A5F8G6E0 FRMD7 PTHR45858:SF1 FERM DOMAIN CONTAINING PROTEIN FERM DOMAIN-CONTAINING PROTEIN 7 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 regulation of neuron projection development#GO:0010975;regulation of biological process#GO:0050789;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035 MONDO|Ensembl=ENSMODG00000011458.4|UniProtKB=F6QWR8 F6QWR8 HMCN1 PTHR44427:SF18 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 OBSCURIN cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000012194.5|UniProtKB=F7CEG7 F7CEG7 SEMA3B PTHR11036:SF37 SEMAPHORIN SEMAPHORIN-3B signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;taxis#GO:0042330;response to chemical#GO:0042221;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;axon development#GO:0061564;axon guidance#GO:0007411;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;chemotaxis#GO:0006935;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;locomotion#GO:0040011 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000049767.1|UniProtKB=A0A5F8H9J4 A0A5F8H9J4 HPS6 PTHR14696:SF2 HERMANSKY-PUDLAK SYNDROME 6 PROTEIN BLOC-2 COMPLEX MEMBER HPS6 cellular process#GO:0009987;lysosome localization#GO:0032418;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;localization within membrane#GO:0051668;organelle localization#GO:0051640;intracellular protein localization#GO:0008104;localization#GO:0051179;cellular localization#GO:0051641 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular protein-containing complex#GO:0140535;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosomal membrane#GO:0005765;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000025608.3|UniProtKB=F6QBV2 F6QBV2 LOC100025850 PTHR18952:SF120 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 2 hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;biological regulation#GO:0065007;regulation of pH#GO:0006885;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;regulation of intracellular pH#GO:0051453;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 apical part of cell#GO:0045177;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000004766.4|UniProtKB=F6VPM2 F6VPM2 COL4A1 PTHR24023:SF854 COLLAGEN ALPHA COLLAGEN ALPHA-1(IV) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000002813.4|UniProtKB=F7EJC7 F7EJC7 PTHR11339:SF396 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED SCO-SPONDIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000019594.4|UniProtKB=F6Y8N6 F6Y8N6 ZSWIM6 PTHR22619:SF3 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 6 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul2-RING ubiquitin ligase complex#GO:0031462 MONDO|Ensembl=ENSMODG00000024307.2|UniProtKB=F7EHZ8 F7EHZ8 LOC100024081 PTHR48018:SF91 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8U1-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000029094.2|UniProtKB=F6QC52 F6QC52 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008429.4|UniProtKB=A0A5F8G8X4 A0A5F8G8X4 PTHR33667:SF7 SI:DKEY-57N24.6 CILIA AND FLAGELLA ASSOCIATED PROTEIN 92 MONDO|Ensembl=ENSMODG00000015841.2|UniProtKB=A0A5F8GT56 A0A5F8GT56 PTHR23024:SF222 ARYLACETAMIDE DEACETYLASE ARYLACETAMIDE DEACETYLASE hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;glycerolipid catabolic process#GO:0046503;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 deacetylase#PC00087 MONDO|Ensembl=ENSMODG00000045017.1|UniProtKB=A0A5F8H6S1 A0A5F8H6S1 ANAPC11 PTHR11210:SF1 RING BOX ANAPHASE-PROMOTING COMPLEX SUBUNIT 11 binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;protein modification by small protein conjugation#GO:0032446;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;positive regulation of cellular component organization#GO:0051130;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of organelle organization#GO:0010638;regulation of mitotic cell cycle phase transition#GO:1901990;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cell cycle#GO:0045787;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;regulation of chromosome separation#GO:1905818;regulation of chromosome segregation#GO:0051983;positive regulation of mitotic nuclear division#GO:0045840;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;catabolic process#GO:0009056;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;post-translational protein modification#GO:0043687;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of chromosome organization#GO:0033044;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of mitotic cell cycle#GO:0045931;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000002844.4|UniProtKB=A0A5F8G4R1 A0A5F8G4R1 LOC100013197 PTHR12411:SF902 CYSTEINE PROTEASE FAMILY C1-RELATED PROCATHEPSIN L cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000016697.4|UniProtKB=F7DLT2 F7DLT2 SS18L1 PTHR23107:SF21 SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN CALCIUM-RESPONSIVE TRANSACTIVATOR transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular component organization#GO:0051130;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of cell differentiation#GO:0045597;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;regulation of dendrite morphogenesis#GO:0048814;regulation of neurogenesis#GO:0050767;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;positive regulation of cell projection organization#GO:0031346;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of biosynthetic process#GO:0009889;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;regulation of cell projection organization#GO:0031344 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000023579.3|UniProtKB=F7CSM2 F7CSM2 LOC100616741 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000004849.4|UniProtKB=F6U4N6 F6U4N6 KIAA1958 PTHR46963:SF1 SIMILAR TO RIKEN CDNA E130308A19 KIAA1958 HOMOLOG MONDO|Ensembl=ENSMODG00000007370.4|UniProtKB=F6TNN2 F6TNN2 PTHR11334:SF70 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G PROTEIN-COUPLED RECEPTOR MEMBER X2 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000007833.4|UniProtKB=A0A5F8HA25 A0A5F8HA25 PLXNA1 PTHR22625:SF35 PLEXIN PLEXIN-A1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of nervous system development#GO:0051960;system development#GO:0048731;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;developmental process#GO:0032502;cellular developmental process#GO:0048869;negative regulation of cell adhesion#GO:0007162;plasma membrane bounded cell projection organization#GO:0120036;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;positive regulation of axonogenesis#GO:0050772;cellular component organization#GO:0016043;regulation of multicellular organismal development#GO:2000026;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;cell projection organization#GO:0030030;signaling#GO:0023052;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cell projection morphogenesis#GO:0048858;regulation of axonogenesis#GO:0050770;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;synapse organization#GO:0050808;positive regulation of cell projection organization#GO:0031346;anatomical structure development#GO:0048856;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;neuron projection morphogenesis#GO:0048812;regulation of cell differentiation#GO:0045595;regulation of plasma membrane bounded cell projection organization#GO:0120035;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cell shape#GO:0008360;positive regulation of multicellular organismal process#GO:0051240;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;synapse assembly#GO:0007416;cell development#GO:0048468;neuron differentiation#GO:0030182;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of cell development#GO:0010720;nervous system development#GO:0007399 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Axon guidance mediated by semaphorins#P00007>PlexinA1#P00334 MONDO|Ensembl=ENSMODG00000003960.4|UniProtKB=F7FYQ7 F7FYQ7 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular process#GO:0009987;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000019888.4|UniProtKB=F6W6B1 F6W6B1 CREB3L1 PTHR46004:SF1 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Transcription regulation by bZIP transcription factor#P00055>CREB#P01383 MONDO|Ensembl=ENSMODG00000012059.5|UniProtKB=A0A5F8GDN0 A0A5F8GDN0 TBX3 PTHR11267:SF91 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 MONDO|Ensembl=ENSMODG00000012620.4|UniProtKB=A0A5F8H6L2 A0A5F8H6L2 GTF3C5 PTHR13230:SF5 GENERAL TRANSCRIPTION FACTOR IIIC, POLYPEPTIDE 5 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 5 macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;rRNA transcription#GO:0009303;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 transcription factor TFIIIC complex#GO:0000127;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000036760.1|UniProtKB=A0A5F8HF28 A0A5F8HF28 PTHR24271:SF61 KALLIKREIN-RELATED INACTIVE SERINE PROTEASE 37-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;biological regulation#GO:0065007;protein maturation#GO:0051604;gene expression#GO:0010467;regulation of reproductive process#GO:2000241;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;extracellular region#GO:0005576;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000006121.3|UniProtKB=F7EI30 F7EI30 RAB2B PTHR47979:SF50 DRAB11-RELATED RAS-RELATED PROTEIN RAB-2B GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;transport#GO:0006810;establishment of localization#GO:0051234;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of secretion#GO:0051047;localization#GO:0051179;regulation of secretion#GO:0051046;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000008983.3|UniProtKB=F7BQG4 F7BQG4 PTHR24100:SF149 BUTYROPHILIN BG ANTIGEN 1, MHCB REGION-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000003297.4|UniProtKB=A0A5F8GWN8 A0A5F8GWN8 NAALAD2 PTHR10404:SF38 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE 2 catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000024957.1|UniProtKB=F6UCF6 F6UCF6 GPR17 PTHR24232:SF44 G-PROTEIN COUPLED RECEPTOR URACIL NUCLEOTIDE_CYSTEINYL LEUKOTRIENE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018285.5|UniProtKB=F6PWU5 F6PWU5 AKAP3 PTHR10226:SF9 A KINASE ANCHOR PROTEIN A-KINASE ANCHOR PROTEIN 3 protein kinase A binding#GO:0051018;binding#GO:0005488;protein binding#GO:0005515 cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;intracellular protein localization#GO:0008104;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;localization#GO:0051179;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;macromolecule localization#GO:0033036;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;9+2 motile cilium#GO:0097729;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;sperm principal piece#GO:0097228 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020130.2|UniProtKB=F7D6D6 F7D6D6 LOC100025858 PTHR48001:SF115 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1S1-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011893.5|UniProtKB=F7EH96 F7EH96 BRDT PTHR22880:SF175 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN TESTIS-SPECIFIC PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000004830.4|UniProtKB=A0A5F8H824 A0A5F8H824 MTMR14 PTHR13524:SF2 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR14 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000046070.1|UniProtKB=A0A5F8GMZ6 A0A5F8GMZ6 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000018951.4|UniProtKB=F7GAR0 F7GAR0 USP53 PTHR22975:SF6 UBIQUITIN SPECIFIC PROTEINASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 53 response to external stimulus#GO:0009605;system process#GO:0003008;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;nervous system process#GO:0050877;sensory perception of sound#GO:0007605;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000008052.3|UniProtKB=F6Z9Y0 F6Z9Y0 ANAPC15 PTHR22526:SF2 ANAPHASE PROMOTING COMPLEX C SUBUNIT 15, PSEUDOGENE-RELATED ANAPHASE PROMOTING COMPLEX C SUBUNIT 15, PSEUDOGENE-RELATED regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cell cycle phase transition#GO:1901987;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of cell communication#GO:0010646;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of mitotic cell cycle#GO:0007346;regulation of signal transduction#GO:0009966;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;regulation of chromosome separation#GO:1905818;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of chromosome segregation#GO:0051983;regulation of response to stimulus#GO:0048583;regulation of chromosome organization#GO:0033044;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965 intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000001708.4|UniProtKB=F6RMK8 F6RMK8 RBBP5 PTHR44040:SF1 RETINOBLASTOMA-BINDING PROTEIN 5 RETINOBLASTOMA-BINDING PROTEIN 5 intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000010982.3|UniProtKB=F7GHJ7 F7GHJ7 CRHR1 PTHR45620:SF2 PDF RECEPTOR-LIKE PROTEIN-RELATED CORTICOTROPIN-RELEASING HORMONE RECEPTOR 1 G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;hormone binding#GO:0042562;molecular transducer activity#GO:0060089;binding#GO:0005488;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Cortocotropin releasing factor receptor signaling pathway#P04380>CRHR1#P04451 MONDO|Ensembl=ENSMODG00000013228.4|UniProtKB=F7EDC7 F7EDC7 ZDHHC9 PTHR22883:SF71 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC9 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein targeting#GO:0006605;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000009184.5|UniProtKB=A0A5F8GG33 A0A5F8GG33 SP3 PTHR23235:SF3 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 C2H2 zinc finger transcription factor#PC00248 CCKR signaling map#P06959>SP3#P07041 MONDO|Ensembl=ENSMODG00000018013.4|UniProtKB=F7AKJ9 F7AKJ9 SCML4 PTHR12247:SF85 POLYCOMB GROUP PROTEIN SEX COMB ON MIDLEG-LIKE PROTEIN 4 binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682;protein binding#GO:0005515 regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000006587.5|UniProtKB=A0A5F8HLF4 A0A5F8HLF4 PTHR10037:SF221 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 9 SUBUNIT ALPHA monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated sodium channel activity#GO:0005248 regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transmission of nerve impulse#GO:0019226;system process#GO:0003008;transport#GO:0006810;multicellular organismal process#GO:0032501;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;sensory perception#GO:0007600;nervous system process#GO:0050877;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;sensory perception of pain#GO:0019233;action potential#GO:0001508;sodium ion transport#GO:0006814 axon#GO:0030424;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;transporter complex#GO:1990351;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000002155.4|UniProtKB=F6YEY5 F6YEY5 NPY1R PTHR24235:SF24 NEUROPEPTIDE Y RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000679.4|UniProtKB=F6WMA0 F6WMA0 THBS1 PTHR10199:SF78 THROMBOSPONDIN THROMBOSPONDIN-1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 regulation of vasculature development#GO:1901342;negative regulation of cellular process#GO:0048523;regulation of cell population proliferation#GO:0042127;negative regulation of angiogenesis#GO:0016525;regulation of anatomical structure morphogenesis#GO:0022603;regulation of angiogenesis#GO:0045765;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;negative regulation of cell population proliferation#GO:0008285;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of multicellular organismal process#GO:0051239 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 p53 pathway#P00059>TSP1#G01566 MONDO|Ensembl=ENSMODG00000002351.4|UniProtKB=F7GLK0 F7GLK0 PTHR11890:SF9 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR-LIKE 2 cell communication#GO:0007154;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;signaling#GO:0023052;regulation of response to external stimulus#GO:0032101;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009100.4|UniProtKB=F7FCJ8 F7FCJ8 DNAJC1 PTHR44653:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 1 DNAJ HOMOLOG SUBFAMILY C MEMBER 1 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000023684.3|UniProtKB=F6PKQ1 F6PKQ1 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000007363.4|UniProtKB=F7ADC7 F7ADC7 PTHR13211:SF1 TELOMERASE CAJAL BODY PROTEIN 1 TELOMERASE CAJAL BODY PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000000604.4|UniProtKB=F6TB99 F6TB99 LRRC40 PTHR45752:SF160 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 40 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000040041.1|UniProtKB=F7DGA7 F7DGA7 LOC100022972 PTHR26452:SF828 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000029161.2|UniProtKB=K7E4G9 K7E4G9 PTHR45847:SF15 FATTY ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;amidase activity#GO:0004040 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;small molecule catabolic process#GO:0044282 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000045389.1|UniProtKB=A0A5F8HD53 A0A5F8HD53 PTHR47613:SF1 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 4 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 4 reproductive process#GO:0022414;fertilization#GO:0009566;cellular process#GO:0009987;single fertilization#GO:0007338;cell-cell recognition#GO:0009988;cell recognition#GO:0008037;sexual reproduction#GO:0019953;sperm-egg recognition#GO:0035036 membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000009872.4|UniProtKB=F6VUL3 F6VUL3 DCLRE1A PTHR23240:SF6 DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED DNA CROSS-LINK REPAIR 1A PROTEIN catalytic activity, acting on DNA#GO:0140097;DNA exonuclease activity#GO:0004529;damaged DNA binding#GO:0003684;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;hydrolase activity#GO:0016787;DNA binding#GO:0003677;exonuclease activity#GO:0004527;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular response to stress#GO:0033554;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;response to stress#GO:0006950;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000002114.5|UniProtKB=A0A5F8G4S0 A0A5F8G4S0 BCL11A PTHR45993:SF5 B-CELL LYMPHOMA/LEUKEMIA 11 BCL11 TRANSCRIPTION FACTOR A sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of cellular component organization#GO:0051129;negative regulation of biological process#GO:0048519;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of neuron projection development#GO:0010975;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000008408.4|UniProtKB=F7B8C7 F7B8C7 SACS PTHR15600:SF44 SACSIN SACSIN heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 MONDO|Ensembl=ENSMODG00000042018.1|UniProtKB=A0A5F8GK03 A0A5F8GK03 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016449.4|UniProtKB=F7A470 F7A470 SDF4 PTHR10827:SF98 RETICULOCALBIN 45 KDA CALCIUM-BINDING PROTEIN binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 calmodulin-related#PC00061;calcium-binding protein#PC00060 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830 MONDO|Ensembl=ENSMODG00000025373.1|UniProtKB=F6ZZG9 F6ZZG9 ACTBL2 PTHR11937:SF168 ACTIN BETA-ACTIN-LIKE PROTEIN 2 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cell junction#GO:0030054;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039 Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944;Cadherin signaling pathway#P00012>F-actin#P00470;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 MONDO|Ensembl=ENSMODG00000029507.2|UniProtKB=K7E5T1 K7E5T1 LOC103094472 PTHR19325:SF317 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING COMPLEMENT DECAY-ACCELERATING FACTOR complement component#PC00078;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000012299.2|UniProtKB=F7EJ84 F7EJ84 HCAR1 PTHR46048:SF3 HYDROXYCARBOXYLIC ACID RECEPTOR 2 HYDROXYCARBOXYLIC ACID RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006200.4|UniProtKB=F6ZTN3 F6ZTN3 PTHR22999:SF43 PX SERINE/THREONINE KINASE PXK SORTING NEXIN-16 small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167 cellular process#GO:0009987;early endosome to late endosome transport#GO:0045022;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;metabolic process#GO:0008152;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;transport#GO:0006810;vacuolar transport#GO:0007034;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;macromolecule metabolic process#GO:0043170;endosomal transport#GO:0016197 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;late endosome#GO:0005770;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769 MONDO|Ensembl=ENSMODG00000015526.3|UniProtKB=A0A5F8HBY8 A0A5F8HBY8 VDAC3 PTHR11743:SF28 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL NON-SELECTIVE VOLTAGE-GATED ION CHANNEL VDAC3 monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;channel activity#GO:0015267;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic anion channel activity#GO:0008308;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509 transport#GO:0006810;mitochondrial transmembrane transport#GO:1990542;intracellular transport#GO:0046907;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;mitochondrial transport#GO:0006839 membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000009983.4|UniProtKB=A0A5F8HJT9 A0A5F8HJT9 MAP3K3 PTHR24361:SF656 MITOGEN-ACTIVATED KINASE KINASE KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 3 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;FGF signaling pathway#P00021>MEKK1-5#P00634;B cell activation#P00010>MEKK#P00369;EGF receptor signaling pathway#P00018>MEKK1-5#P00553;Integrin signalling pathway#P00034>ERK#P00907 MONDO|Ensembl=ENSMODG00000014073.4|UniProtKB=F6TST1 F6TST1 ARHGEF6 PTHR46026:SF2 RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 6 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;lamellipodium assembly#GO:0030032;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lamellipodium#GO:0030027;cellular anatomical structure#GO:0110165;cell leading edge#GO:0031252 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000005306.4|UniProtKB=F7DM61 F7DM61 SPAG17 PTHR21963:SF1 PF6 SPERM-ASSOCIATED ANTIGEN 17 plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;cilium movement#GO:0003341;microtubule-based transport#GO:0099111;microtubule bundle formation#GO:0001578;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018 organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;membraneless organelle#GO:0043228;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axonemal central apparatus#GO:1990716;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000006161.4|UniProtKB=F6ZJP8 F6ZJP8 BCL6B PTHR24399:SF37 ZINC FINGER AND BTB DOMAIN-CONTAINING B-CELL CLL_LYMPHOMA 6 MEMBER B PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;immune system process#GO:0002376;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of response to external stimulus#GO:0032101;regulation of multicellular organismal process#GO:0051239;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of DNA-templated transcription#GO:0006355;regulation of cell population proliferation#GO:0042127;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;immune response#GO:0006955;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000027544.1|UniProtKB=K7E2I4 K7E2I4 PTHR12420:SF4 PHD FINGER PROTEIN PHD FINGER PROTEIN 11 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000039812.1|UniProtKB=A0A5F8GN67 A0A5F8GN67 PROZ PTHR24278:SF20 COAGULATION FACTOR VITAMIN K-DEPENDENT PROTEIN Z catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 blood coagulation#GO:0007596;regulation of biological quality#GO:0065008;wound healing#GO:0042060;biological regulation#GO:0065007;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;regulation of body fluid levels#GO:0050878;coagulation#GO:0050817;hemostasis#GO:0007599;response to stress#GO:0006950;response to wounding#GO:0009611 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 Blood coagulation#P00011>PZ#P00407 MONDO|Ensembl=ENSMODG00000002213.4|UniProtKB=F7G3D4 F7G3D4 CARD14 PTHR14559:SF1 CASPASE RECRUITMENT DOMAIN FAMILY CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 14 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000051349.1|UniProtKB=F7DTG4 F7DTG4 CMTR1 PTHR16121:SF0 CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1-RELATED CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1 RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;O-methyltransferase activity#GO:0008171 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000001437.4|UniProtKB=F7BC96 F7BC96 IRX4 PTHR11211:SF16 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-4 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000015388.5|UniProtKB=F6TKN8 F6TKN8 STK36 PTHR22983:SF7 PROTEIN KINASE RELATED SERINE_THREONINE-PROTEIN KINASE 36 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Hedgehog signaling pathway#P00025>Fused#P00686 MONDO|Ensembl=ENSMODG00000002698.3|UniProtKB=F6ZAL6 F6ZAL6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001471.5|UniProtKB=F7AP70 F7AP70 PWP1 PTHR14091:SF0 PERIODIC TRYPTOPHAN PROTEIN 1 PERIODIC TRYPTOPHAN PROTEIN 1 HOMOLOG DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682 regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase I#GO:0006356;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase I#GO:0045943;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000020509.5|UniProtKB=H9H7K8 H9H7K8 CAMKK1 PTHR43895:SF26 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 MONDO|Ensembl=ENSMODG00000027700.2|UniProtKB=K7DZY0 K7DZY0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000019324.3|UniProtKB=F6XTB3 F6XTB3 PTHR11984:SF50 CONNEXIN GAP JUNCTION DELTA-2 PROTEIN passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267 cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular process#GO:0009987 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cell junction protein#PC00070;gap junction#PC00105 MONDO|Ensembl=ENSMODG00000004555.3|UniProtKB=F6R5G0 F6R5G0 CRYGN PTHR11818:SF22 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN N structural molecule activity#GO:0005198 sensory perception of light stimulus#GO:0050953;visual perception#GO:0007601;visual system development#GO:0150063;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;sensory perception#GO:0007600;nervous system process#GO:0050877;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;multicellular organism development#GO:0007275;animal organ development#GO:0048513;system process#GO:0003008 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000023726.3|UniProtKB=F6TXV9 F6TXV9 LOC100024672 PTHR11588:SF247 TUBULIN TUBULIN BETA-4B CHAIN carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 tubulin#PC00228;cytoskeletal protein#PC00085 Huntington disease#P00029>Microtubule#P00780;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>beta-Tubulin#P00790 MONDO|Ensembl=ENSMODG00000043297.1|UniProtKB=A0A5F8GGK8 A0A5F8GGK8 PTHR23073:SF13 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 7 isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 proteasome complex#GO:0000502;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000050521.1|UniProtKB=A0A5F8GM02 A0A5F8GM02 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000043185.1|UniProtKB=F7E8I5 F7E8I5 LOC100019150 PTHR26450:SF7 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016499.4|UniProtKB=F7EQJ0 F7EQJ0 PTHR12305:SF102 PHOSPHATASE WITH HOMOLOGY TO TENSIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;vasculature development#GO:0001944;multicellular organism development#GO:0007275;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501 cell projection#GO:0042995;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;protein phosphatase#PC00195 PI3 kinase pathway#P00048>PTEN#P01189;p53 pathway#P00059>PTEN#P01480;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#G04675;p53 pathway feedback loops 2#P04398>PTEN#P04658;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#P00905;p53 pathway feedback loops 2#P04398>PTEN#G04714;CCKR signaling map#P06959>PTEN#P07071;Hypoxia response via HIF activation#P00030>PTEN#P00824;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PTEN#P00849;p53 pathway#P00059>PTEN#G01579 MONDO|Ensembl=ENSMODG00000003582.4|UniProtKB=A0A5F8GML0 A0A5F8GML0 PRRX1 PTHR46385:SF1 PAIRED MESODERM HOMEOBOX PROTEIN 1-RELATED PAIRED MESODERM HOMEOBOX PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000005860.4|UniProtKB=F6S512 F6S512 LOC103103279 PTHR43544:SF38 SHORT-CHAIN DEHYDROGENASE/REDUCTASE C-FACTOR-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000037600.1|UniProtKB=F6X0W8 F6X0W8 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014495.2|UniProtKB=F7FKL8 F7FKL8 RPS7 PTHR11278:SF0 40S RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN ES7 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;ribosome#GO:0005840;small-subunit processome#GO:0032040;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000038825.1|UniProtKB=A0A5F8HC56 A0A5F8HC56 REST PTHR24403:SF102 ZINC FINGER PROTEIN RE1-SILENCING TRANSCRIPTION FACTOR transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;regulation of cell differentiation#GO:0045595;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of neuron differentiation#GO:0045664;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000051131.1|UniProtKB=A0A5F8G6K8 A0A5F8G6K8 SRP14 PTHR12013:SF0 SIGNAL RECOGNITION PARTICLE 14 KD PROTEIN SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN establishment of protein localization to endoplasmic reticulum#GO:0072599;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;protein targeting#GO:0006605;protein transport#GO:0015031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;localization within membrane#GO:0051668 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000017974.4|UniProtKB=F7BV32 F7BV32 FOXJ2 PTHR46078:SF1 FORKHEAD BOX PROTEIN J2 FAMILY MEMBER FORKHEAD BOX PROTEIN J2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000019765.4|UniProtKB=A0A5F8G3X7 A0A5F8G3X7 PPFIA1 PTHR12587:SF15 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA-1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 presynapse#GO:0098793;cellular anatomical structure#GO:0110165;synapse#GO:0045202;presynaptic active zone#GO:0048786;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020113.2|UniProtKB=A0A5F8GWD9 A0A5F8GWD9 PTHR12595:SF0 POS9-ACTIVATING FACTOR FAP7-RELATED ADENYLATE KINASE ISOENZYME 6 phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside phosphate binding#GO:1901265;nucleobase-containing compound kinase activity#GO:0019205;ATP binding#GO:0005524;binding#GO:0005488;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;kinase activity#GO:0016301;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000007169.5|UniProtKB=A0A5F8GHU8 A0A5F8GHU8 OSBPL5 PTHR10972:SF213 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 5 alcohol binding#GO:0043178;cholesterol binding#GO:0015485;steroid binding#GO:0005496;lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;sterol binding#GO:0032934 establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;organophosphate ester transport#GO:0015748;lipid transport#GO:0006869;macromolecule localization#GO:0033036 membrane#GO:0016020;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000016210.4|UniProtKB=A0A5F8GV19 A0A5F8GV19 SERINC3 PTHR10383:SF51 SERINE INCORPORATOR SERINE INCORPORATOR 3 cellular anatomical structure#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000023613.3|UniProtKB=F7BS98 F7BS98 VN2R594 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019674.3|UniProtKB=H9H7E3 H9H7E3 PTHR45620:SF8 PDF RECEPTOR-LIKE PROTEIN-RELATED CALCITONIN RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;regulation of biological quality#GO:0065008 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;axon#GO:0030424 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011006.4|UniProtKB=A0A5F8GY48 A0A5F8GY48 MAD2L2 PTHR11842:SF10 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000002248.3|UniProtKB=F7DF74 F7DF74 PTHR16466:SF6 TELOMERE REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 TELOMERIC REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cellular process#GO:0009987;organelle organization#GO:0006996;telomere capping#GO:0016233;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance via telomere lengthening#GO:0010833;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;telomere organization#GO:0032200 nucleus#GO:0005634;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;nuclear telomere cap complex#GO:0000783 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000017396.3|UniProtKB=F6SKV0 F6SKV0 PTHR14455:SF0 ASKOPOS S100P-BINDING PROTEIN MONDO|Ensembl=ENSMODG00000004695.3|UniProtKB=F6TQQ8 F6TQQ8 HHIPL2 PTHR19328:SF54 HEDGEHOG-INTERACTING PROTEIN HHIP-LIKE PROTEIN 2 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000036831.1|UniProtKB=A0A5F8G2M2 A0A5F8G2M2 LOC100017303 PTHR13622:SF14 THIAMIN PYROPHOSPHOKINASE THIAMINE PYROPHOSPHOKINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;alcohol biosynthetic process#GO:0046165;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137;transferase#PC00220 Thiamin metabolism#P02780>Thiamine kinase#P03176 MONDO|Ensembl=ENSMODG00000024450.1|UniProtKB=F6Z900 F6Z900 CHST1 PTHR10704:SF36 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 1 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 amino sugar metabolic process#GO:0006040;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000009450.4|UniProtKB=F6RDX7 F6RDX7 KDM3A PTHR12549:SF7 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN LYSINE-SPECIFIC DEMETHYLASE 3A demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;protein demethylase activity#GO:0140457;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;chromatin DNA binding#GO:0031490;histone demethylase activity#GO:0032452;DNA binding#GO:0003677;histone modifying activity#GO:0140993;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000025493.3|UniProtKB=A0A5F8G3P2 A0A5F8G3P2 IQCK PTHR34927:SF1 IQ DOMAIN-CONTAINING PROTEIN K IQ DOMAIN-CONTAINING PROTEIN K MONDO|Ensembl=ENSMODG00000013762.4|UniProtKB=F6TX16 F6TX16 TEAD3 PTHR11834:SF7 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED TRANSCRIPTIONAL ENHANCER FACTOR TEF-5 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cell communication#GO:0007154;embryonic organ development#GO:0048568;animal gross anatomical part developmental process#GO:0160108;hippo signaling#GO:0035329;embryo development#GO:0009790;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000042542.1|UniProtKB=A0A5F8H2E7 A0A5F8H2E7 DUSP19 PTHR46377:SF1 DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 regulation of JNK cascade#GO:0046328;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of MAPK cascade#GO:0043408;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000017269.4|UniProtKB=F6T3N2 F6T3N2 NPDC1 PTHR11636:SF139 POU DOMAIN POU DOMAIN PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000014734.5|UniProtKB=A0A5F8GM78 A0A5F8GM78 TSPOAP1 PTHR14234:SF20 RIM BINDING PROTEIN-RELATED PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR-ASSOCIATED PROTEIN 1 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018593.5|UniProtKB=F7FCT7 F7FCT7 FHIP1B PTHR21705:SF4 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK-INTERACTING PROTEIN 1B vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;lysosome organization#GO:0007040;early endosome to late endosome transport#GO:0045022;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;vesicle organization#GO:0016050;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;lytic vacuole organization#GO:0080171;vacuolar transport#GO:0007034;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;vacuole organization#GO:0007033;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000022955.2|UniProtKB=F6S1Z9 F6S1Z9 LOC100015449 PTHR11143:SF11 60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL24 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000012262.3|UniProtKB=F6YGI0 F6YGI0 MYOT PTHR10075:SF23 BASIGIN RELATED MYOTILIN cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000000454.4|UniProtKB=F6USG0 F6USG0 RP2 PTHR15440:SF0 XRP2 PROTEIN PROTEIN XRP2 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport#GO:0006810;post-Golgi vesicle-mediated transport#GO:0006892;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000005342.5|UniProtKB=F7CHD5 F7CHD5 PTHR28597:SF1 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT-ASSOCIATED REGULATORY PROTEIN VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT-ASSOCIATED REGULATORY PROTEIN protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 regulation of secretion#GO:0051046;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 voltage-gated ion channel#PC00241;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000002172.3|UniProtKB=F7GEI1 F7GEI1 REL PTHR24169:SF4 NUCLEAR FACTOR NF-KAPPA-B PROTEIN PROTO-ONCOGENE C-REL sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;defense response#GO:0006952;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;positive regulation of DNA-templated transcription#GO:0045893;canonical NF-kappaB signal transduction#GO:0007249;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;response to peptide#GO:1901652;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;regulation of biological process#GO:0050789;positive regulation of transcription by RNA polymerase II#GO:0045944;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;non-canonical NF-kappaB signal transduction#GO:0038061 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252 Toll receptor signaling pathway#P00054>NFkappaB#P01354;Apoptosis signaling pathway#P00006>NFkappaB#P00297;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859 MONDO|Ensembl=ENSMODG00000008617.4|UniProtKB=A0A5F8HEW9 A0A5F8HEW9 HNRNPLL PTHR15592:SF13 MATRIN 3/NUCLEAR PROTEIN 220-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L-LIKE RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000017571.4|UniProtKB=F7BS62 F7BS62 STRN3 PTHR15653:SF3 STRIATIN STRIATIN-3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057 postsynapse#GO:0098794;cell body#GO:0044297;neuron projection#GO:0043005;protein-containing complex#GO:0032991;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;dendritic tree#GO:0097447;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000004817.4|UniProtKB=A0A5F8GEM8 A0A5F8GEM8 HTRA2 PTHR22939:SF127 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA2, MITOCHONDRIAL peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;proteolysis#GO:0006508;protein metabolic process#GO:0019538;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;cell death#GO:0008219;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000011237.3|UniProtKB=F6S753 F6S753 PTHR24028:SF318 CADHERIN-87A PROTOCADHERIN BETA-16 cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000047592.1|UniProtKB=A0A5F8GA75 A0A5F8GA75 PTHR39235:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Y PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Y enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;phospholipid metabolic process#GO:0006644;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783 transferase#PC00220 MONDO|Ensembl=ENSMODG00000046551.1|UniProtKB=A0A5F8HEN0 A0A5F8HEN0 PTHR22829:SF7 DEP DOMAIN PROTEIN DEP DOMAIN-CONTAINING MTOR-INTERACTING PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;molecular function activator activity#GO:0140677;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;protein kinase regulator activity#GO:0019887;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;kinase inhibitor activity#GO:0019210 regulation of TORC1 signaling#GO:1903432;negative regulation of cellular process#GO:0048523;negative regulation of TORC1 signaling#GO:1904262;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;cell communication#GO:0007154;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000029011.2|UniProtKB=K7E3Q4 K7E3Q4 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000010043.4|UniProtKB=F6TTN8 F6TTN8 ALG5 PTHR10859:SF91 GLYCOSYL TRANSFERASE DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000019905.3|UniProtKB=F6VQ91 F6VQ91 ACP2 PTHR11567:SF180 ACID PHOSPHATASE-RELATED LYSOSOMAL ACID PHOSPHATASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;acid phosphatase activity#GO:0003993;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;cellular component organization#GO:0016043;organelle organization#GO:0006996;lytic vacuole organization#GO:0080171;cellular process#GO:0009987;lysosome organization#GO:0007040 vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000004223.2|UniProtKB=A0A5F8GRM8 A0A5F8GRM8 RWDD4 PTHR21275:SF1 RWD DOMAIN-CONTAINING PROTEIN 4 RWD DOMAIN-CONTAINING PROTEIN 4 MONDO|Ensembl=ENSMODG00000038464.1|UniProtKB=A0A5F8G2R9 A0A5F8G2R9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016151.3|UniProtKB=F7D6V8 F7D6V8 LOC100022878 PTHR26453:SF16 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003515.4|UniProtKB=A0A5F8HIS7 A0A5F8HIS7 PTHR15397:SF3 SODIUM-GLUCOSE COTRANSPORTER REGULATORY PROTEIN -RELATED DNA DAMAGE INDUCIBLE 1 HOMOLOG 2 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000007873.3|UniProtKB=F7EB92 F7EB92 GPR183 PTHR24237:SF7 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 183 steroid binding#GO:0005496;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;lipid binding#GO:0008289;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;sterol binding#GO:0032934;binding#GO:0005488 response to stimulus#GO:0050896;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;regulation of leukocyte activation#GO:0002694;positive regulation of cell population proliferation#GO:0008284;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;cell activation involved in immune response#GO:0002263;B cell activation involved in immune response#GO:0002312;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;lymphocyte activation#GO:0046649;response to chemical#GO:0042221;taxis#GO:0042330;regulation of multicellular organismal process#GO:0051239;regulation of mononuclear cell proliferation#GO:0032944;regulation of B cell activation#GO:0050864;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;lymphocyte activation involved in immune response#GO:0002285;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of mononuclear cell proliferation#GO:0032946;regulation of leukocyte proliferation#GO:0070663;B cell activation#GO:0042113;regulation of B cell proliferation#GO:0030888;leukocyte activation involved in immune response#GO:0002366;positive regulation of leukocyte activation#GO:0002696;immune effector process#GO:0002252;regulation of immune system process#GO:0002682;cell motility#GO:0048870;regulation of cellular process#GO:0050794;locomotion#GO:0040011;positive regulation of B cell proliferation#GO:0030890;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;positive regulation of lymphocyte activation#GO:0051251;regulation of cell population proliferation#GO:0042127;cell chemotaxis#GO:0060326;cell activation#GO:0001775;chemotaxis#GO:0006935;positive regulation of lymphocyte proliferation#GO:0050671;cell migration#GO:0016477;regulation of lymphocyte proliferation#GO:0050670;multicellular organismal process#GO:0032501;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;leukocyte chemotaxis#GO:0030595;response to external stimulus#GO:0009605;leukocyte migration#GO:0050900;positive regulation of leukocyte proliferation#GO:0070665 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000008371.3|UniProtKB=F7CDX2 F7CDX2 RAB1B PTHR24073:SF1096 DRAB5-RELATED RAS-RELATED PROTEIN RAB-1B pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;organelle assembly#GO:0070925;catabolic process#GO:0009056;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;intracellular transport#GO:0046907;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cell body#GO:0044297;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000015908.2|UniProtKB=F7AFN8 F7AFN8 PTHR18847:SF0 20 KD NUCLEAR CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA processing#GO:0006397;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;RNA transport#GO:0050658;RNA localization#GO:0006403;catabolic process#GO:0009056;nucleobase-containing compound transport#GO:0015931;regulation of macromolecule metabolic process#GO:0060255;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;regulation of macromolecule biosynthetic process#GO:0010556;nitrogen compound transport#GO:0071705;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;RNA export from nucleus#GO:0006405;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;transport#GO:0006810;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000028607.2|UniProtKB=K7E0Y5 K7E0Y5 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019323.4|UniProtKB=A0A5F8GZ75 A0A5F8GZ75 MYO18A PTHR45615:SF13 MYOSIN HEAVY CHAIN, NON-MUSCLE UNCONVENTIONAL MYOSIN-XVIIIA protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000000990.4|UniProtKB=A0A5F8HB82 A0A5F8HB82 UCHL3 PTHR10589:SF24 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L3 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000038293.1|UniProtKB=F7FSE8 F7FSE8 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000003770.3|UniProtKB=F7EG75 F7EG75 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000018537.4|UniProtKB=F7GD67 F7GD67 STAG1 PTHR11199:SF6 STROMAL ANTIGEN COHESIN SUBUNIT SA-1 binding#GO:0005488;chromatin binding#GO:0003682 sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cell cycle process#GO:0022402;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000003030.4|UniProtKB=F6Q1W2 F6Q1W2 ALYREF PTHR19965:SF35 RNA AND EXPORT FACTOR BINDING PROTEIN THO COMPLEX SUBUNIT 4 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;localization#GO:0051179;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;gene expression#GO:0010467 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000028219.2|UniProtKB=K7E2C7 K7E2C7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000020742.4|UniProtKB=F7A026 F7A026 GNRHR PTHR24241:SF22 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR GONADOTROPIN-RELEASING HORMONE RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>GnRHR#P06727;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Gonadotropin-releasing hormone receptor pathway#P06664>GnRHR#G06676;Gonadotropin-releasing hormone receptor pathway#P06664>GnRHR#G06892 MONDO|Ensembl=ENSMODG00000049929.1|UniProtKB=A0A5F8GGR5 A0A5F8GGR5 PTHR21183:SF18 RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053 protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000041283.1|UniProtKB=A0A5F8HK72 A0A5F8HK72 PTHR23226:SF430 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 1010-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000003047.3|UniProtKB=F6PP51 F6PP51 LTB4R2 PTHR24230:SF8 G-PROTEIN COUPLED RECEPTOR LEUKOTRIENE B4 RECEPTOR 2 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000043904.1|UniProtKB=A0A5F8GNL3 A0A5F8GNL3 monDomV1R1266 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045934.1|UniProtKB=A0A5F8HE80 A0A5F8HE80 PSMA2 PTHR11599:SF16 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-2 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 intracellular protein-containing complex#GO:0140535;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 MONDO|Ensembl=ENSMODG00000014642.3|UniProtKB=F6YNX2 F6YNX2 CRIP2 PTHR46074:SF2 CYSTEINE-RICH PROTEIN CRIP FAMILY MEMBER CYSTEINE-RICH PROTEIN 2 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000010283.4|UniProtKB=F6VLX1 F6VLX1 TMEM255A PTHR33721:SF1 TRANSMEMBRANE PROTEIN 255B-LIKE TRANSMEMBRANE PROTEIN 255A MONDO|Ensembl=ENSMODG00000027971.2|UniProtKB=K7E424 K7E424 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000045096.1|UniProtKB=A0A5F8GKC4 A0A5F8GKC4 PTHR15416:SF6 CAMP-DEPENDENT PROTEIN KINASE INHIBITOR/PKI CAMP-DEPENDENT PROTEIN KINASE INHIBITOR BETA enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;kinase inhibitor activity#GO:0019210;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 kinase inhibitor#PC00139;kinase modulator#PC00140 MONDO|Ensembl=ENSMODG00000013071.4|UniProtKB=F7FBP4 F7FBP4 SNX20 PTHR20939:SF1 SORTING NEXIN 20, 21 SORTING NEXIN-20 phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;vesicle membrane#GO:0012506 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013237.4|UniProtKB=F7ECV7 F7ECV7 GLO1 PTHR10374:SF30 LACTOYLGLUTATHIONE LYASE GLYOXALASE I LACTOYLGLUTATHIONE LYASE metabolite interconversion enzyme#PC00262;lyase#PC00144 MONDO|Ensembl=ENSMODG00000007924.4|UniProtKB=F7GIA7 F7GIA7 MTPAP PTHR12271:SF133 POLY A POLYMERASE CID PAP -RELATED POLY(A) RNA POLYMERASE, MITOCHONDRIAL adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098 modification-dependent macromolecule catabolic process#GO:0043632;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;RNA 3'-end processing#GO:0031123;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA processing#GO:0006397;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;RNA processing#GO:0006396;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174 MONDO|Ensembl=ENSMODG00000027622.1|UniProtKB=K7E123 K7E123 PTHR12713:SF12 VACUOLAR ATP SYNTHASE SUBUNIT G V-TYPE PROTON ATPASE SUBUNIT G 1 homeostatic process#GO:0042592;cellular component organization#GO:0016043;monoatomic ion transport#GO:0006811;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;vesicle-mediated transport#GO:0016192;developmental maturation#GO:0021700;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;vesicle organization#GO:0016050;cellular homeostasis#GO:0019725;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;synaptic vesicle maturation#GO:0016188;cellular component organization or biogenesis#GO:0071840;proton transmembrane transport#GO:1902600;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;developmental process#GO:0032502 bounding membrane of organelle#GO:0098588;transporter complex#GO:1990351;cell junction#GO:0030054;proton-transporting two-sector ATPase complex#GO:0016469;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;presynapse#GO:0098793;secretory vesicle#GO:0099503;ATPase dependent transmembrane transport complex#GO:0098533;exocytic vesicle#GO:0070382;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;vacuolar membrane#GO:0005774;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular membrane-bounded organelle#GO:0043231;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;synaptic vesicle#GO:0008021;cation-transporting ATPase complex#GO:0090533;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;membrane protein complex#GO:0098796 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000008978.5|UniProtKB=F7FRL8 F7FRL8 ZC3H4 PTHR13119:SF23 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 4 DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription regulator activity#GO:0140110 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of DNA-templated transcription elongation#GO:0032784;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000017294.4|UniProtKB=F6SLW8 F6SLW8 GLRA2 PTHR18945:SF28 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-2 excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;transport#GO:0006810;chloride transport#GO:0006821;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;chloride transmembrane transport#GO:1902476;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cell junction#GO:0030054;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;synaptic membrane#GO:0097060;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;organelle#GO:0043226;plasma membrane#GO:0005886;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000004503.4|UniProtKB=F6VA05 F6VA05 NYAP1 PTHR22633:SF2 NEURONAL TYROSINE-PHOSPHORYLATED PHOSPHOINOSITIDE-3-KINASE ADAPTER 2-RELATED NEURONAL TYROSINE-PHOSPHORYLATED PHOSPHOINOSITIDE-3-KINASE ADAPTER 1 cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004291.4|UniProtKB=A0A5F8HFX5 A0A5F8HFX5 ALG14 PTHR12154:SF4 GLYCOSYL TRANSFERASE-RELATED UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG14 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;transferase complex, transferring phosphorus-containing groups#GO:0061695;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 transferase#PC00220 MONDO|Ensembl=ENSMODG00000010021.3|UniProtKB=F6U9X7 F6U9X7 PTHR26454:SF152 OLFACTORY RECEPTOR OLFACTORY RECEPTOR OLFR212-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038674.1|UniProtKB=A0A5F8H0F0 A0A5F8H0F0 PTHR28342:SF1 MONOOXYGENASE P33MONOX-RELATED MONOOXYGENASE P33MONOX-RELATED cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000006126.4|UniProtKB=A0A5F8GP47 A0A5F8GP47 PARVG PTHR12114:SF1 PARVIN GAMMA-PARVIN protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 establishment or maintenance of cell polarity#GO:0007163;cell adhesion#GO:0007155;actin filament-based process#GO:0030029;cell-substrate adhesion#GO:0031589;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;cell projection organization#GO:0030030;actin cytoskeleton organization#GO:0030036;regulation of developmental process#GO:0050793;substrate adhesion-dependent cell spreading#GO:0034446;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000012454.3|UniProtKB=F6PHU9 F6PHU9 SP6 PTHR23235:SF23 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002654.4|UniProtKB=F7DI68 F7DI68 VPS8 PTHR12616:SF16 VACUOLAR PROTEIN SORTING VPS41 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular component organization#GO:0016043 vesicle tethering complex#GO:0099023;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasm#GO:0005737;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000009454.4|UniProtKB=F7FZJ0 F7FZJ0 FRY PTHR12295:SF29 FURRY-RELATED PROTEIN FURRY HOMOLOG multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 cell division site#GO:0032153;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020805.4|UniProtKB=F6S7C2 F6S7C2 PAQR3 PTHR20855:SF15 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 macromolecule localization#GO:0033036;protein localization to Golgi apparatus#GO:0034067;intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000009768.4|UniProtKB=H9H6C2 H9H6C2 PTHR26453:SF255 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013318.4|UniProtKB=F7GJH2 F7GJH2 HYOU1 PTHR45639:SF37 HSC70CB, ISOFORM G-RELATED HYPOXIA UP-REGULATED PROTEIN 1 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589 negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;regulation of cellular response to stress#GO:0080135;negative regulation of cell communication#GO:0010648;negative regulation of programmed cell death#GO:0043069;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;regulation of apoptotic process#GO:0042981 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 chaperone#PC00072;Hsp70 family chaperone#PC00027 MONDO|Ensembl=ENSMODG00000001337.1|UniProtKB=F7FWC5 F7FWC5 LYG2 PTHR31698:SF4 LYSOZYME G FAMILY MEMBER LYSOZYME G-LIKE PROTEIN 2 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;lysozyme activity#GO:0003796;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 defense response to Gram-positive bacterium#GO:0050830;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;response to external stimulus#GO:0009605;defense response#GO:0006952 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000003771.4|UniProtKB=F7AAG6 F7AAG6 HOMER3 PTHR10918:SF4 HOMER HOMER PROTEIN HOMOLOG 3 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;glutamate receptor signaling pathway#GO:0007215;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;cell surface receptor signaling pathway#GO:0007166;regulation of localization#GO:0032879;regulation of transport#GO:0051049 intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794;cell junction#GO:0030054;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000007770.4|UniProtKB=A0A5F8GYS9 A0A5F8GYS9 EML3 PTHR13720:SF15 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 3 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000002173.3|UniProtKB=F7GEI5 F7GEI5 LOC100029207 PTHR10704:SF4 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 6 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058 Golgi apparatus subcompartment#GO:0098791;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000004107.4|UniProtKB=A0A5F8H3A8 A0A5F8H3A8 TENM3 PTHR11219:SF65 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-3 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;axonogenesis#GO:0007409;neuron development#GO:0048666;synaptic membrane adhesion#GO:0099560;generation of neurons#GO:0048699;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell junction organization#GO:0034330;system development#GO:0048731;anatomical structure development#GO:0048856;synapse organization#GO:0050808;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon development#GO:0061564;axon guidance#GO:0007411;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502 synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000008500.4|UniProtKB=F7FTQ9 F7FTQ9 GKAP1 PTHR14899:SF0 G KINASE ANCHORING PROTEIN 1 G KINASE-ANCHORING PROTEIN 1 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000024323.1|UniProtKB=F7DGE9 F7DGE9 LOC100619219 PTHR48018:SF44 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8J1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020678.3|UniProtKB=F7DL74 F7DL74 CLOCK PTHR46055:SF2 CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;circadian regulation of gene expression#GO:0032922;circadian rhythm#GO:0007623;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;rhythmic process#GO:0048511;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Circadian clock system#P00015>Clock#P00501 MONDO|Ensembl=ENSMODG00000023679.3|UniProtKB=A0A5F8G514 A0A5F8G514 ACOT7 PTHR11049:SF24 ACYL COENZYME A THIOESTER HYDROLASE CYTOSOLIC ACYL COENZYME A THIOESTER HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617 nucleoside phosphate metabolic process#GO:0006753;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;nucleobase-containing compound metabolic process#GO:0006139;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 esterase#PC00097 MONDO|Ensembl=ENSMODG00000018751.4|UniProtKB=F7EF29 F7EF29 PTHR24241:SF69 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR GONADOTROPIN-RELEASING HORMONE II RECEPTOR-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 MONDO|Ensembl=ENSMODG00000003090.4|UniProtKB=F6PKK9 F6PKK9 PRICKLE2 PTHR24211:SF18 LIM DOMAIN-CONTAINING PROTEIN PRICKLE-LIKE PROTEIN 2 developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of organelle assembly#GO:1902115;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of cell junction assembly#GO:1901888;anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;system development#GO:0048731;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron projection development#GO:0031175;cellular process#GO:0009987;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of synapse organization#GO:0050807;regulation of biological quality#GO:0065008;neuron development#GO:0048666;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of postsynapse organization#GO:0099175;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020380.4|UniProtKB=F7F689 F7F689 CCT2 PTHR11353:SF23 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT BETA protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829;chaperonin-containing T-complex#GO:0005832;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein folding chaperone complex#GO:0101031 chaperonin#PC00073 MONDO|Ensembl=ENSMODG00000019868.4|UniProtKB=F6RQV5 F6RQV5 EXT2 PTHR11062:SF381 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-2 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000014920.4|UniProtKB=F7FVR9 F7FVR9 ATF6B PTHR46164:SF2 ATF6, ISOFORM C CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-6 BETA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;response to unfolded protein#GO:0006986;regulation of DNA-templated transcription#GO:0006355;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Apoptosis signaling pathway#P00006>ATF#P00302 MONDO|Ensembl=ENSMODG00000000689.4|UniProtKB=F6WM29 F6WM29 LOC100015203 PTHR11588:SF78 TUBULIN TUBULIN ALPHA CHAIN anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367 cellular process#GO:0009987;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 cytoskeletal protein#PC00085;tubulin#PC00228 MONDO|Ensembl=ENSMODG00000045607.1|UniProtKB=A0A5F8HBW3 A0A5F8HBW3 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000018585.4|UniProtKB=F7FD62 F7FD62 APBB1 PTHR14058:SF5 AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B AMYLOID BETA PRECURSOR PROTEIN BINDING FAMILY B MEMBER 1 peptide binding#GO:0042277;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;DNA damage response#GO:0006974;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to stress#GO:0033554;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Alzheimer disease-presenilin pathway#P00004>Fe65#P00126;Alzheimer disease-amyloid secretase pathway#P00003>Fe65#P00087 MONDO|Ensembl=ENSMODG00000012978.4|UniProtKB=F7CSS8 F7CSS8 TCTA PTHR32267:SF2 T-CELL LEUKEMIA TRANSLOCATION-ALTERED GENE PROTEIN T-CELL LEUKEMIA TRANSLOCATION-ALTERED GENE PROTEIN MONDO|Ensembl=ENSMODG00000028110.2|UniProtKB=K7E586 K7E586 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000027856.2|UniProtKB=K7E4S6 K7E4S6 DNAAF8 PTHR35977:SF1 CHROMOSOME 16 OPEN READING FRAME 71 DYNEIN AXONEMAL ASSEMBLY FACTOR 8 intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000011777.4|UniProtKB=F7CVU5 F7CVU5 ANTXR1 PTHR16059:SF11 ANTHRAX TOXIN RECEPTOR ANTHRAX TOXIN RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000000077.2|UniProtKB=F6QT62 F6QT62 PTHR21237:SF25 GRPE PROTEIN GRPE PROTEIN HOMOLOG 1, MITOCHONDRIAL nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839 protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000002024.4|UniProtKB=F6QX12 F6QX12 WASHC4 PTHR31409:SF0 WASH COMPLEX SUBUNIT 4 WASH COMPLEX SUBUNIT 4 intracellular transport#GO:0046907;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000025706.3|UniProtKB=F6TIF2 F6TIF2 PTHR16677:SF1 HEMATOPOIETIC PROGENITOR CELL ANTIGEN CD34 HEMATOPOIETIC PROGENITOR CELL ANTIGEN CD34 cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cell-substrate adhesion#GO:0031589 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000018417.5|UniProtKB=F6XUX2 F6XUX2 PTHR13802:SF66 MUCIN 4-RELATED MUCIN-4 homeostatic process#GO:0042592;epithelial structure maintenance#GO:0010669;digestion#GO:0007586;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;system process#GO:0003008;tissue homeostasis#GO:0001894;multicellular organismal-level homeostasis#GO:0048871 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000002436.4|UniProtKB=A0A5F8GVK4 A0A5F8GVK4 RPTOR PTHR12848:SF22 REGULATORY-ASSOCIATED PROTEIN OF MTOR REGULATORY-ASSOCIATED PROTEIN OF MTOR protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of growth#GO:0040008;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;regulation of catabolic process#GO:0009894;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;positive regulation of growth#GO:0045927;TORC1 signaling#GO:0038202;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to acid chemical#GO:0001101;cellular process#GO:0009987;response to stress#GO:0006950;TOR signaling#GO:0031929;response to chemical#GO:0042221;regulation of cell growth#GO:0001558;positive regulation of cell growth#GO:0030307 intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;TOR complex#GO:0038201;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000002350.3|UniProtKB=F7GLK3 F7GLK3 PRPF38B PTHR23142:SF2 PRE-MRNA-SPLICING FACTOR 38A-RELATED PRE-MRNA-SPLICING FACTOR 38B RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000004643.5|UniProtKB=A0A5F8G5Z4 A0A5F8G5Z4 PTHR15819:SF8 TRANSMEMBRANE PROTEIN FAM155 NALCN CHANNEL AUXILIARY FACTOR 2 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108 cellular process#GO:0009987;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;transport#GO:0006810;localization#GO:0051179;import into cell#GO:0098657;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000040483.1|UniProtKB=A0A5F8H513 A0A5F8H513 CD82 PTHR19282:SF44 TETRASPANIN CD82 ANTIGEN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 p53 pathway#P00059>KAI#G04704 MONDO|Ensembl=ENSMODG00000045871.1|UniProtKB=K7DZU6 K7DZU6 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000012617.2|UniProtKB=F6S2N3 F6S2N3 LOC100030141 PTHR26453:SF95 OLFACTORY RECEPTOR OLFACTORY RECEPTOR FAMILY 10 SUBFAMILY AI MEMBER 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024101.2|UniProtKB=F6XJU7 F6XJU7 PTHR24230:SF10 G-PROTEIN COUPLED RECEPTOR CYSTEINYL LEUKOTRIENE RECEPTOR 2 G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000016038.4|UniProtKB=F6YUY4 F6YUY4 NTHL1 PTHR43286:SF7 ENDONUCLEASE III-LIKE PROTEIN 1 ENDONUCLEASE III-LIKE PROTEIN 1 DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520 DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009;DNA glycosylase#PC00010 MONDO|Ensembl=ENSMODG00000000731.4|UniProtKB=A0A5F8GZY7 A0A5F8GZY7 SLIT2 PTHR45836:SF2 SLIT HOMOLOG SLIT HOMOLOG 2 PROTEIN protein binding#GO:0005515;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367;binding#GO:0005488;signaling receptor binding#GO:0005102;heparin binding#GO:0008201 system development#GO:0048731;anatomical structure development#GO:0048856;chemotaxis#GO:0006935;locomotion#GO:0040011;regulation of cellular process#GO:0050794;regulation of growth#GO:0040008;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of cell growth#GO:0030308;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon development#GO:0061564;axon guidance#GO:0007411;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;taxis#GO:0042330;response to chemical#GO:0042221;regulation of cell growth#GO:0001558;cellular process#GO:0009987;neuron projection development#GO:0031175 Axon guidance mediated by Slit/Robo#P00008>Slit#P00342 MONDO|Ensembl=ENSMODG00000042135.1|UniProtKB=A0A5F8H7Q2 A0A5F8H7Q2 LOC100030002 PTHR10489:SF958 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR 5 LIKE-RELATED cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515 response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;defense response#GO:0006952;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;signal transduction#GO:0007165;immune response#GO:0006955;cellular process#GO:0009987;response to stress#GO:0006950;cell chemotaxis#GO:0060326;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;signaling#GO:0023052;locomotion#GO:0040011;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cytoplasm#GO:0005737;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000040697.1|UniProtKB=A0A5F8HA76 A0A5F8HA76 ID3 PTHR11723:SF16 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-3 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;nervous system development#GO:0007399;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>Id3#P06711 MONDO|Ensembl=ENSMODG00000001291.4|UniProtKB=F7C094 F7C094 RXRG PTHR24083:SF100 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR RXR-GAMMA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067 response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;hormone-mediated signaling pathway#GO:0009755;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;intracellular receptor signaling pathway#GO:0030522;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000019147.4|UniProtKB=A0A5F8H947 A0A5F8H947 LIG3 PTHR45674:SF20 DNA LIGASE 1/3 FAMILY MEMBER DNA LIGASE 3 ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097 DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;DNA ligase#PC00012 MONDO|Ensembl=ENSMODG00000018082.4|UniProtKB=F7FTH1 F7FTH1 ASCC3 PTHR24075:SF6 SEC63 DOMAIN-CONTAINING ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3 catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000442.5|UniProtKB=F6UT25 F6UT25 ACTR5 PTHR11937:SF16 ACTIN ACTIN-RELATED PROTEIN 5 enzyme regulator activity#GO:0030234;structural molecule activity#GO:0005198;molecular function regulator activity#GO:0098772;structural constituent of cytoskeleton#GO:0005200 chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Ino80 complex#GO:0031011;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991 actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000028597.2|UniProtKB=K7E5A3 K7E5A3 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;immune response#GO:0006955;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000010811.4|UniProtKB=F7BZC1 F7BZC1 COL3A1 PTHR24023:SF604 COLLAGEN ALPHA COLLAGEN ALPHA-1(III) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;skin development#GO:0043588;skeletal system morphogenesis#GO:0048705;cellular process#GO:0009987;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;system development#GO:0048731;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;interstitial matrix#GO:0005614;supramolecular complex#GO:0099080 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000041334.1|UniProtKB=F7CUC9 F7CUC9 LOC100618929 PTHR26452:SF930 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000047467.1|UniProtKB=K7E603 K7E603 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000893.3|UniProtKB=F7A7J7 F7A7J7 PTHR22847:SF751 WD40 REPEAT PROTEIN WD REPEAT DOMAIN 5B histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463 gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;transcription initiation at RNA polymerase II promoter#GO:0006367;transcription initiation-coupled chromatin remodeling#GO:0045815;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;chromatin remodeling#GO:0006338;DNA-templated transcription initiation#GO:0006352;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891 transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;NSL complex#GO:0044545;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000024335.2|UniProtKB=F7A7F6 F7A7F6 LOC100618633 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016065.3|UniProtKB=F7GIS3 F7GIS3 CLDN11 PTHR12002:SF6 CLAUDIN CLAUDIN-11 cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;cell adhesion#GO:0007155;cell-cell junction assembly#GO:0007043 apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 MONDO|Ensembl=ENSMODG00000042403.1|UniProtKB=A0A5F8G5Q1 A0A5F8G5Q1 SPCS2 PTHR13085:SF0 MICROSOMAL SIGNAL PEPTIDASE 25 KDA SUBUNIT SIGNAL PEPTIDASE COMPLEX SUBUNIT 2 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;protein targeting to ER#GO:0045047;establishment of protein localization#GO:0045184;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;establishment of protein localization to endoplasmic reticulum#GO:0072599;biosynthetic process#GO:0009058;localization#GO:0051179;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein targeting#GO:0006605 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;peptidase complex#GO:1905368;cytoplasm#GO:0005737 protease#PC00190 Vasopressin synthesis#P04395>Signal Peptidase#P04589 MONDO|Ensembl=ENSMODG00000045730.1|UniProtKB=F7ET81 F7ET81 LOC100028609 PTHR48002:SF153 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018312.4|UniProtKB=F6PTI2 F6PTI2 CCND2 PTHR10177:SF66 CYCLINS G1_S-SPECIFIC CYCLIN-D2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;G1/S transition of mitotic cell cycle#GO:0000082;positive regulation of cell cycle G1/S phase transition#GO:1902808;positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047;cell cycle process#GO:0022402;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;regulation of G1/S transition of mitotic cell cycle#GO:2000045;mitotic cell cycle phase transition#GO:0044772;regulation of mitotic cell cycle phase transition#GO:1901990 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228 kinase activator#PC00138 PI3 kinase pathway#P00048>Cyclin d#G01546;Cell cycle#P00013>Cyclin D#P00484 MONDO|Ensembl=ENSMODG00000024462.1|UniProtKB=F7GB03 F7GB03 LOC100010451 PTHR10836:SF111 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE oxidoreductase activity#GO:0016491;glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nicotinamide nucleotide metabolic process#GO:0046496;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 Huntington disease#P00029>GAPDH#P00810;Glycolysis#P00024>Glyceraldehyde 3-phosphate dehydrogenase#P00676 MONDO|Ensembl=ENSMODG00000006076.3|UniProtKB=F7FES2 F7FES2 PARP1 PTHR10459:SF112 DNA LIGASE POLY [ADP-RIBOSE] POLYMERASE 1 NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096 response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 MONDO|Ensembl=ENSMODG00000043391.1|UniProtKB=A0A5F8HAC3 A0A5F8HAC3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000005697.3|UniProtKB=F6UKN3 F6UKN3 PARD6A PTHR14102:SF9 PAR-6-RELATED PARTITIONING DEFECTIVE 6 HOMOLOG ALPHA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cytoskeleton organization#GO:0007010;cell junction organization#GO:0034330;cellular process#GO:0009987;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;microtubule cytoskeleton organization#GO:0000226;cell-cell junction maintenance#GO:0045217;cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;establishment or maintenance of cell polarity#GO:0007163 plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;protein kinase complex#GO:1902911;transferase complex#GO:1990234;apical part of cell#GO:0045177;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;apical plasma membrane#GO:0016324;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 cell junction protein#PC00070;tight junction#PC00214 MONDO|Ensembl=ENSMODG00000028631.2|UniProtKB=K7DZW6 K7DZW6 C2orf66 PTHR47620:SF1 CHROMOSOME 2 OPEN READING FRAME 66 GENE, 34066-RELATED MONDO|Ensembl=ENSMODG00000017932.4|UniProtKB=A0A5F8GX76 A0A5F8GX76 DDO PTHR11530:SF31 D-AMINO ACID OXIDASE D-ASPARTATE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 peroxisome#GO:0005777;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782 oxidase#PC00175 MONDO|Ensembl=ENSMODG00000005396.4|UniProtKB=F7GG66 F7GG66 MLC1 PTHR17597:SF0 MEMBRANE PROTEIN MLC1 MEMBRANE PROTEIN MLC1 biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000025599.3|UniProtKB=F6QCM9 F6QCM9 DIMT1 PTHR11727:SF34 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a rRNA#GO:0140102;rRNA (adenine) methyltransferase activity#GO:0016433 rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA methylation#GO:0031167 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000007142.4|UniProtKB=F6RZ40 F6RZ40 OSGEP PTHR11735:SF14 TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000006318.4|UniProtKB=A0A5F8H7E9 A0A5F8H7E9 TBXT PTHR11267:SF83 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR T transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cellular process#GO:0009987;embryo development#GO:0009790;heart development#GO:0007507;cell fate specification#GO:0001708;anterior/posterior pattern specification#GO:0009952;anatomical structure formation involved in morphogenesis#GO:0048646;mesoderm development#GO:0007498;animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;gastrulation#GO:0007369;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;cell differentiation#GO:0030154;formation of primary germ layer#GO:0001704;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;tissue development#GO:0009888;regionalization#GO:0003002;multicellular organismal process#GO:0032501;mesoderm formation#GO:0001707;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;mesoderm morphogenesis#GO:0048332;heart morphogenesis#GO:0003007;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;embryo development ending in birth or egg hatching#GO:0009792;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 MONDO|Ensembl=ENSMODG00000022960.2|UniProtKB=F6RH12 F6RH12 MRPL50 PTHR31542:SF1 39A RIBOSOMAL PROTEIN L50, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML50 intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000016128.3|UniProtKB=F7DSC5 F7DSC5 LOC100022990 PTHR26453:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018142.4|UniProtKB=A0A5F8GSJ9 A0A5F8GSJ9 MANEA PTHR13572:SF1 ENDO-ALPHA-1,2-MANNOSIDASE GLYCOPROTEIN ENDO-ALPHA-1,2-MANNOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000006777.4|UniProtKB=F7BTH3 F7BTH3 ZFHX4 PTHR45891:SF2 ZINC FINGER HOMEOBOX PROTEIN ZINC FINGER HOMEOBOX PROTEIN 4 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000000457.3|UniProtKB=F6US49 F6US49 LOC100025748 PTHR11346:SF97 GALECTIN GALECTIN-1 protein binding#GO:0005515;extracellular matrix binding#GO:0050840;carbohydrate binding#GO:0030246;oligosaccharide binding#GO:0070492;binding#GO:0005488;laminin binding#GO:0043236 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000044143.1|UniProtKB=A0A5F8H9N6 A0A5F8H9N6 FAM53C PTHR28567:SF4 PROTEIN FAM53A-LIKE ISOFORM X1 PROTEIN FAM53C cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000017909.4|UniProtKB=F6TMZ0 F6TMZ0 CAPN3 PTHR10183:SF329 CALPAIN CALPAIN-3 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;proteolysis#GO:0006508;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 MONDO|Ensembl=ENSMODG00000000538.4|UniProtKB=F6XMY8 F6XMY8 LGALS2 PTHR11346:SF104 GALECTIN GALECTIN-2 carbohydrate binding#GO:0030246;binding#GO:0005488;carbohydrate derivative binding#GO:0097367 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000021577.1|UniProtKB=Q65CI9 Q65CI9 ATP8 PTHR13722:SF0 ATP SYNTHASE PROTEIN 8 ATP SYNTHASE F(0) COMPLEX SUBUNIT 8 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;proton channel activity#GO:0015252;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987 proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;proton-transporting ATP synthase complex#GO:0045259 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000028664.2|UniProtKB=K7E2W7 K7E2W7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000045103.1|UniProtKB=A0A5F8G5Q0 A0A5F8G5Q0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010226.4|UniProtKB=A0A5F8HHB9 A0A5F8HHB9 PTHR12684:SF2 PUTATIVE PHOSPHOTRANSFERASE TRNA 2'-PHOSPHOTRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;phosphotransferase activity, alcohol group as acceptor#GO:0016773 gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000047649.1|UniProtKB=A0A5F8G2U0 A0A5F8G2U0 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000020408.5|UniProtKB=F7BEB0 F7BEB0 ZFC3H1 PTHR21563:SF3 ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000037475.1|UniProtKB=F7G840 F7G840 LOC100027978 PTHR48002:SF68 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D10 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038542.1|UniProtKB=F7BR58 F7BR58 LOC100009948 PTHR26453:SF108 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003787.4|UniProtKB=F7AA43 F7AA43 JPH4 PTHR23085:SF14 GH28348P JUNCTOPHILIN-4 regulation of signaling#GO:0023051;regulation of synaptic plasticity#GO:0048167;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177 membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;sarcoplasm#GO:0016528;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000000588.4|UniProtKB=F6TRR3 F6TRR3 GPX7 PTHR11592:SF5 GLUTATHIONE PEROXIDASE PROTEIN PEROXIDASE GPX7 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601 response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887 oxidoreductase#PC00176;peroxidase#PC00180 MONDO|Ensembl=ENSMODG00000039368.1|UniProtKB=A0A5F8H6K9 A0A5F8H6K9 PTHR14581:SF4 FAMILY NOT NAMED PROLINE-RICH PROTEIN 15 MONDO|Ensembl=ENSMODG00000014431.4|UniProtKB=F7ATX4 F7ATX4 CLTC PTHR10292:SF7 CLATHRIN HEAVY CHAIN RELATED CLATHRIN HEAVY CHAIN 1 protein binding#GO:0005515;binding#GO:0005488;clathrin binding#GO:0030276 transport#GO:0006810;protein-containing complex organization#GO:0043933;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;localization#GO:0051179;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cell cycle#GO:0007049;endocytosis#GO:0006897;mitotic cell cycle#GO:0000278 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;clathrin-coated endocytic vesicle#GO:0045334;cytoskeleton#GO:0005856;clathrin-coated vesicle#GO:0030136;spindle#GO:0005819 vesicle coat protein#PC00235;membrane traffic protein#PC00150 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738 MONDO|Ensembl=ENSMODG00000022837.3|UniProtKB=H9H9K3 H9H9K3 PTHR23226:SF348 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 497 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000037750.1|UniProtKB=A0A5F8GN40 A0A5F8GN40 PTHR19422:SF123 GAG RETROVIRAL POLYPROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000041093.1|UniProtKB=A0A5F8G602 A0A5F8G602 PTHR23339:SF55 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE TYPE IVA 1 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;positive regulation of cell motility#GO:2000147;positive regulation of cell migration#GO:0030335;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000020751.4|UniProtKB=F6ZZE4 F6ZZE4 TMPRSS11B PTHR24253:SF29 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 11B-LIKE PROTEIN peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000047937.1|UniProtKB=A0A5F8GCE4 A0A5F8GCE4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000043502.1|UniProtKB=A0A5F8H0I0 A0A5F8H0I0 EPGN PTHR10740:SF10 TRANSFORMING GROWTH FACTOR ALPHA EPIGEN signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 positive regulation of cell population proliferation#GO:0008284;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;positive regulation of cellular component organization#GO:0051130;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of organelle organization#GO:0010638;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of nuclear division#GO:0051783;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;cell surface receptor signaling pathway#GO:0007166;positive regulation of mitotic nuclear division#GO:0045840;regulation of mitotic nuclear division#GO:0007088 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 MONDO|Ensembl=ENSMODG00000005097.3|UniProtKB=F6ZEI9 F6ZEI9 PTHR11960:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 1B translation initiation factor activity#GO:0003743;RNA binding#GO:0003723;translation factor activity#GO:0180051;nucleic acid binding#GO:0003676;binding#GO:0005488 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000008908.3|UniProtKB=F7GL99 F7GL99 PINX1 PTHR23149:SF27 G PATCH DOMAIN CONTAINING PROTEIN PIN2_TERF1-INTERACTING TELOMERASE INHIBITOR 1 molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000020627.4|UniProtKB=F7F3Z9 F7F3Z9 INTS12 PTHR13415:SF2 NUCLEAR FACTOR-RELATED INTEGRATOR COMPLEX SUBUNIT 12 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 integrator complex#GO:0032039;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000014819.2|UniProtKB=F7D2A8 F7D2A8 NOG PTHR10494:SF5 BONE MORPHOGENETIC PROTEIN INHIBITOR, NOGGIN NOGGIN molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;dorsal/ventral pattern formation#GO:0009953;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;system development#GO:0048731;negative regulation of cell communication#GO:0010648;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;animal gross anatomical part developmental process#GO:0160108;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;regionalization#GO:0003002;regulation of BMP signaling pathway#GO:0030510;negative regulation of BMP signaling pathway#GO:0030514;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000051417.1|UniProtKB=A0A5F8HEB7 A0A5F8HEB7 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002191.4|UniProtKB=F7GE45 F7GE45 PFKFB2 PTHR10606:SF48 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE 2 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydrolase activity#GO:0016787;sugar-phosphatase activity#GO:0050308 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase#PC00181;hydrolase#PC00121;carbohydrate phosphatase#PC00066 MONDO|Ensembl=ENSMODG00000004955.4|UniProtKB=F7FX76 F7FX76 PTHR15932:SF2 UBIQUITIN INTERACTION MOTIF-CONTAINING PROTEIN 1 BRCA1-A COMPLEX SUBUNIT RAP80 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of DNA metabolic process#GO:0051054;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA repair#GO:0045739;biological regulation#GO:0065007;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;regulation of response to stress#GO:0080134;DNA repair#GO:0006281;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;cellular component organization#GO:0016043;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chromatin remodeling#GO:0006338;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;regulation of cellular response to stress#GO:0080135;response to stress#GO:0006950;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;site of double-strand break#GO:0035861;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000023119.2|UniProtKB=F6W507 F6W507 PTHR11158:SF29 MSF1/PX19 RELATED PRELI DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 organophosphate ester transport#GO:0015748;lipid transport#GO:0006869;phospholipid transport#GO:0015914;macromolecule localization#GO:0033036;localization#GO:0051179;establishment of localization#GO:0051234;lipid localization#GO:0010876;transport#GO:0006810 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000001008.4|UniProtKB=K7E1I3 K7E1I3 MOV10 PTHR10887:SF322 DNA2/NAM7 HELICASE FAMILY RNA HELICASE MOV-10 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000021572.1|UniProtKB=Q65CJ1 Q65CJ1 MT-CO1 PTHR10422:SF18 CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055 respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980 membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;transporter complex#GO:1990351 oxidase#PC00175;oxidoreductase#PC00176 ATP synthesis#P02721>Cytochrome oxidase aa3#P02793 MONDO|Ensembl=ENSMODG00000023582.2|UniProtKB=F7C8C0 F7C8C0 LOC100011471 PTHR11467:SF179 HISTONE H1 HISTONE H1.4 protein-containing complex binding#GO:0044877;double-stranded DNA binding#GO:0003690;nucleosome binding#GO:0031491;DNA binding#GO:0003677;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490 negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;negative regulation of biological process#GO:0048519;negative regulation of DNA recombination#GO:0045910;cellular component organization#GO:0016043;chromosome condensation#GO:0030261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA recombination#GO:0000018;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000005008.4|UniProtKB=F7F6P3 F7F6P3 ALDH18A1 PTHR11063:SF28 GLUTAMATE SEMIALDEHYDE DEHYDROGENASE DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000016064.3|UniProtKB=F7GIR9 F7GIR9 LOC100023445 PTHR26451:SF976 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000039459.1|UniProtKB=A0A5F8H7R2 A0A5F8H7R2 LOC103105462 PTHR31148:SF1 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618 small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000001504.3|UniProtKB=F7F4G7 F7F4G7 SCAND1 PTHR45935:SF10 PROTEIN ZBED8-RELATED SCAN DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000008732.5|UniProtKB=F6V8X2 F6V8X2 PTHR46756:SF16 TRANSGELIN GAS2-LIKE PROTEIN 1 actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;protein localization to organelle#GO:0033365;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;supramolecular fiber organization#GO:0097435;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;actin filament-based process#GO:0030029;microtubule bundle formation#GO:0001578;regulation of microtubule-based process#GO:0032886;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;protein localization to microtubule cytoskeleton#GO:0072698;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;intracellular protein localization#GO:0008104;actin filament organization#GO:0007015;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;microtubule end#GO:1990752;microtubule#GO:0005874;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;actomyosin#GO:0042641;microtubule plus-end#GO:0035371;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;stress fiber#GO:0001725;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000043068.1|UniProtKB=F7DG55 F7DG55 LOC100022616 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028520.2|UniProtKB=K7DZY9 K7DZY9 PTHR24306:SF0 FAMILY NOT NAMED 7-ALPHA-HYDROXYCHOLEST-4-EN-3-ONE 12-ALPHA-HYDROXYLASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497 MONDO|Ensembl=ENSMODG00000012079.3|UniProtKB=F7G4V3 F7G4V3 LRRC8B PTHR45752:SF40 LEUCINE-RICH REPEAT-CONTAINING VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8B monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253 signaling#GO:0023052;import across plasma membrane#GO:0098739;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;signal transduction#GO:0007165;cellular process#GO:0009987;import into cell#GO:0098657;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;carboxylic acid transmembrane transport#GO:1905039;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;regulation of cellular process#GO:0050794;carbohydrate derivative transport#GO:1901264;cellular response to stimulus#GO:0051716;monoatomic anion transport#GO:0006820;intracellular signal transduction#GO:0035556;localization#GO:0051179;cell communication#GO:0007154;amino acid transmembrane transport#GO:0003333;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;dicarboxylic acid transport#GO:0006835;aspartate transmembrane transport#GO:0015810;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cytoplasm#GO:0005737;plasma membrane#GO:0005886;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000039706.1|UniProtKB=A0A5F8GD64 A0A5F8GD64 LOC100028511 PTHR26452:SF977 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000002935.4|UniProtKB=F6PM73 F6PM73 CCDC138 PTHR34523:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 138 COILED-COIL DOMAIN-CONTAINING PROTEIN 138 MONDO|Ensembl=ENSMODG00000037809.1|UniProtKB=A0A5F8GES8 A0A5F8GES8 PTHR23262:SF50 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-8 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000005644.4|UniProtKB=F7BWC8 F7BWC8 PTHR21650:SF4 MEMBRALIN/KINETOCHORE PROTEIN NUF2 MEMBRALIN regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of response to stimulus#GO:0048584;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of response to endoplasmic reticulum stress#GO:1905897;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of ERAD pathway#GO:1904292;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;positive regulation of protein catabolic process#GO:0045732;regulation of cellular response to stress#GO:0080135;regulation of protein catabolic process#GO:0042176 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000016487.4|UniProtKB=H9H8T2 H9H8T2 BRCC3 PTHR10410:SF51 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED BRCA1_BRCA2-CONTAINING COMPLEX SUBUNIT 3 deubiquitinase activity#GO:0101005;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 translation factor#PC00223;translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000037884.1|UniProtKB=A0A5F8GMC2 A0A5F8GMC2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000011983.3|UniProtKB=F7B9J1 F7B9J1 SCD5 PTHR11351:SF100 ACYL-COA DESATURASE STEAROYL-COA DESATURASE 5 catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;iron ion binding#GO:0005506;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;unsaturated fatty acid biosynthetic process#GO:0006636;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 MONDO|Ensembl=ENSMODG00000006180.4|UniProtKB=F7B4W0 F7B4W0 TDRD5 PTHR22948:SF29 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 5 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006055.2|UniProtKB=A0A5F8GTD4 A0A5F8GTD4 SDHAF2 PTHR12469:SF2 PROTEIN EMI5 HOMOLOG, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 2, MITOCHONDRIAL mitochondrial respiratory chain complex II assembly#GO:0034553;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;electron transport chain#GO:0022900;tricarboxylic acid cycle#GO:0006099;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;metabolic process#GO:0008152;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;aerobic electron transport chain#GO:0019646 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000019361.3|UniProtKB=A0A5F8GCH3 A0A5F8GCH3 NMB PTHR16866:SF3 GASTRIN-RELEASING PEPTIDE NEUROMEDIN B protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488;neuropeptide receptor binding#GO:0071855 regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;regulation of hormone secretion#GO:0046883;regulation of secretion#GO:0051046;positive regulation of signaling#GO:0023056;positive regulation of secretion#GO:0051047;positive regulation of hormone secretion#GO:0046887;regulation of signaling#GO:0023051;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;regulation of transport#GO:0051049;regulation of localization#GO:0032879;biological regulation#GO:0065007;positive regulation of secretion by cell#GO:1903532;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518 MONDO|Ensembl=ENSMODG00000038618.1|UniProtKB=A0A5F8H828 A0A5F8H828 KLF3 PTHR23235:SF48 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008830.4|UniProtKB=F7C0Z9 F7C0Z9 CSPG4 PTHR15036:SF17 PIKACHURIN-LIKE PROTEIN CHONDROITIN SULFATE PROTEOGLYCAN 4 multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000007963.4|UniProtKB=A0A5F8GSS4 A0A5F8GSS4 UGT1A6 PTHR48050:SF7 STEROL 3-BETA-GLUCOSYLTRANSFERASE UDP-GLUCURONOSYLTRANSFERASE 1A6 binding#GO:0005488;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;transferase activity#GO:0016740;catalytic activity#GO:0003824;enzyme inhibitor activity#GO:0004857;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;molecular function regulator activity#GO:0098772 pigment metabolic process#GO:0042440;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;hormone metabolic process#GO:0042445;lipid metabolic process#GO:0006629;developmental process#GO:0032502;sterol metabolic process#GO:0016125;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to steroid hormone#GO:0048545;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;response to hormone#GO:0009725;steroid metabolic process#GO:0008202;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;metabolic process#GO:0008152;cellular response to steroid hormone stimulus#GO:0071383;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of hormone levels#GO:0010817;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;liver development#GO:0001889;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;animal gross anatomical part developmental process#GO:0160108;cellular response to chemical stimulus#GO:0070887;regulation of biological quality#GO:0065008;estrogen metabolic process#GO:0008210 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000016135.3|UniProtKB=A0A5F8HG30 A0A5F8HG30 CISD1 PTHR13680:SF5 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 transaminase activity#GO:0008483;small molecule binding#GO:0036094;binding#GO:0005488;transferase activity#GO:0016740;catalytic activity#GO:0003824;iron-sulfur cluster binding#GO:0051536 homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771 mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 MONDO|Ensembl=ENSMODG00000006342.4|UniProtKB=A0A5F8HA29 A0A5F8HA29 SET PTHR11875:SF67 TESTIS-SPECIFIC Y-ENCODED PROTEIN PROTEIN SET binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393;protein binding#GO:0005515 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000018508.4|UniProtKB=F7B3K2 F7B3K2 AMOTL2 PTHR14826:SF3 ANGIOMOTIN ANGIOMOTIN-LIKE PROTEIN 2 regulation of cellular process#GO:0050794;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;establishment of cell polarity#GO:0030010;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;system development#GO:0048731;intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;biological regulation#GO:0065007;tube development#GO:0035295;regulation of locomotion#GO:0040012;cell migration#GO:0016477;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of cell migration#GO:0030334;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514;cellular component organization#GO:0016043;angiogenesis#GO:0001525;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;hippo signaling#GO:0035329;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;anchoring junction#GO:0070161;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;bicellular tight junction#GO:0005923 MONDO|Ensembl=ENSMODG00000050409.1|UniProtKB=A0A5F8H7B1 A0A5F8H7B1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000006733.4|UniProtKB=A0A5F8GZS9 A0A5F8GZS9 NEURL4 PTHR12429:SF14 NEURALIZED NEURALIZED-LIKE PROTEIN 4 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neuralized#P01117 MONDO|Ensembl=ENSMODG00000012441.4|UniProtKB=F6PJG5 F6PJG5 MPHOSPH9 PTHR14926:SF1 M-PHASE PHOSPHOPROTEIN 9 M-PHASE PHOSPHOPROTEIN 9 microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000051339.1|UniProtKB=A0A5F8HBH1 A0A5F8HBH1 PTHR12486:SF5 APRATAXIN-RELATED ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 MONDO|Ensembl=ENSMODG00000010143.4|UniProtKB=F7B736 F7B736 PTHR11481:SF103 IMMUNOGLOBULIN FC RECEPTOR LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR III-A-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;adaptive immune response#GO:0002250;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;immune system process#GO:0002376;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;cell communication#GO:0007154;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000003188.4|UniProtKB=F6SE27 F6SE27 RPH3A PTHR45729:SF3 RABPHILIN, ISOFORM A RABPHILIN-3A regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;export from cell#GO:0140352;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;positive regulation of cellular component organization#GO:0051130;positive regulation of secretion#GO:0051047;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;synaptic signaling#GO:0099536;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;regulation of transport#GO:0051049;positive regulation of vesicle fusion#GO:0031340;regulation of localization#GO:0032879;vesicle-mediated transport in synapse#GO:0099003;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;regulation of exocytosis#GO:0017157;regulation of secretion#GO:0051046;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234 synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;organelle membrane#GO:0031090;postsynapse#GO:0098794;intracellular vesicle#GO:0097708;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;postsynaptic membrane#GO:0045211;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;secretory vesicle#GO:0099503;neuron projection#GO:0043005;presynapse#GO:0098793;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;synaptic membrane#GO:0097060;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;bounding membrane of organelle#GO:0098588 MONDO|Ensembl=ENSMODG00000008969.4|UniProtKB=F7G228 F7G228 PTHR14555:SF1 MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED MELANOPHILIN myosin binding#GO:0017022;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863 myelin protein#PC00161 MONDO|Ensembl=ENSMODG00000005059.4|UniProtKB=A0A5F8G675 A0A5F8G675 RELCH PTHR32059:SF2 RAB11-BINDING PROTEIN RELCH RAB11-BINDING PROTEIN RELCH organic hydroxy compound transport#GO:0015850;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;sterol transport#GO:0015918;transport#GO:0006810;lipid localization#GO:0010876;intracellular transport#GO:0046907;intracellular sterol transport#GO:0032366;lipid transport#GO:0006869;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037 MONDO|Ensembl=ENSMODG00000012999.4|UniProtKB=F7C8N8 F7C8N8 UBASH3B PTHR16469:SF29 UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING PROTEIN B catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of bone resorption#GO:0045124;cell adhesion#GO:0007155;regulation of myeloid cell differentiation#GO:0045637;negative regulation of signaling#GO:0023057;wound healing#GO:0042060;regulation of biological quality#GO:0065008;negative regulation of cell communication#GO:0010648;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;signal transduction#GO:0007165;coagulation#GO:0050817;cell-cell adhesion#GO:0098609;response to stress#GO:0006950;regulation of multicellular organismal process#GO:0051239;negative regulation of signal transduction#GO:0009968;cell surface receptor signaling pathway#GO:0007166;platelet aggregation#GO:0070527;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular response to stimulus#GO:0051716;hemostasis#GO:0007599;regulation of transmembrane transport#GO:0034762;negative regulation of multicellular organismal process#GO:0051241;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;cell activation#GO:0001775;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of tissue remodeling#GO:0034103;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of hemopoiesis#GO:1903706;regulation of cell development#GO:0060284;response to wounding#GO:0009611;regulation of bone remodeling#GO:0046850;homotypic cell-cell adhesion#GO:0034109;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;regulation of monoatomic ion transport#GO:0043269;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of monoatomic cation transmembrane transport#GO:1904062;blood coagulation#GO:0007596;platelet activation#GO:0030168 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000006428.5|UniProtKB=A0A5F8GJ58 A0A5F8GJ58 PTHR23317:SF65 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 6 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 regulation of small GTPase mediated signal transduction#GO:0051056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000023080.2|UniProtKB=F7FR61 F7FR61 LOC103104746 PTHR48001:SF43 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1N1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000050840.1|UniProtKB=A0A5F8HBQ7 A0A5F8HBQ7 monDomV1R1203 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017165.4|UniProtKB=F6QDH4 F6QDH4 CHRNB2 PTHR18945:SF901 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-2 passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;synaptic transmission, cholinergic#GO:0007271;trans-synaptic signaling#GO:0099537;response to nitrogen compound#GO:1901698;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;synaptic signaling#GO:0099536;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896 plasma membrane protein complex#GO:0098797;postsynapse#GO:0098794;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;transporter complex#GO:1990351;cell junction#GO:0030054 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNB2#P06613;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>beta#P01095 MONDO|Ensembl=ENSMODG00000050058.1|UniProtKB=F6V6W6 F6V6W6 PTHR48002:SF118 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006242.3|UniProtKB=F7FRX7 F7FRX7 TRADD PTHR14913:SF0 TUMOR NECROSIS FACTOR RECEPTOR TYPE 1-ASSOCIATED DEATH DOMAIN PROTEIN TUMOR NECROSIS FACTOR RECEPTOR TYPE 1-ASSOCIATED DEATH DOMAIN PROTEIN protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;receptor tyrosine kinase binding#GO:0030971 apoptotic signaling pathway#GO:0097190;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;cellular process#GO:0009987;cell death#GO:0008219;signal transduction#GO:0007165;regulation of biological process#GO:0050789;programmed cell death#GO:0012501 protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235 Apoptosis signaling pathway#P00006>TRADD#P00319 MONDO|Ensembl=ENSMODG00000039502.1|UniProtKB=A0A5F8GUQ5 A0A5F8GUQ5 GNB1L PTHR19854:SF1 TRANSDUCIN BETA-LIKE 3 GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-LIKE PROTEIN 1 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018588.3|UniProtKB=F7FD45 F7FD45 CAVIN3 PTHR15240:SF2 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 3 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane raft#GO:0045121;membrane#GO:0016020;caveola#GO:0005901;intracellular anatomical structure#GO:0005622;plasma membrane raft#GO:0044853;membrane microdomain#GO:0098857 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000014618.3|UniProtKB=F6ZDF6 F6ZDF6 ID2 PTHR11723:SF5 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-2 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;neuron differentiation#GO:0030182;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;nervous system development#GO:0007399 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>Id2#P06804 MONDO|Ensembl=ENSMODG00000049358.1|UniProtKB=A0A5F8H4Z3 A0A5F8H4Z3 MAP7 PTHR15073:SF4 MICROTUBULE-ASSOCIATED PROTEIN ENSCONSIN microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule bundle formation#GO:0001578;regulation of microtubule-based process#GO:0032886;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000003703.4|UniProtKB=K7E160 K7E160 RIF1 PTHR22928:SF4 TELOMERE-ASSOCIATED PROTEIN RIF1 TELOMERE-ASSOCIATED PROTEIN RIF1 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;organelle organization#GO:0006996;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;telomere organization#GO:0032200;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome, telomeric region#GO:0000781;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;chromosome, telomeric repeat region#GO:0140445;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000003568.4|UniProtKB=F7G0T1 F7G0T1 KLHL26 PTHR45632:SF13 LD33804P KELCH-LIKE PROTEIN 26 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 Cul3-RING ubiquitin ligase complex#GO:0031463;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000003857.4|UniProtKB=F7DU21 F7DU21 PTHR34914:SF1 LYMPHOCYTE EXPANSION MOLECULE CILIARY MICROTUBULE-ASSOCIATED PROTEIN 2 MONDO|Ensembl=ENSMODG00000004927.3|UniProtKB=F7BGF7 F7BGF7 LBX2 PTHR24336:SF10 TRANSCRIPTION FACTOR LBX TRANSCRIPTION FACTOR LBX2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000029105.2|UniProtKB=A0A5F8GN80 A0A5F8GN80 FGF1 PTHR11486:SF86 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 1 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;fibroblast growth factor receptor binding#GO:0005104;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 growth factor#PC00112;intercellular signal molecule#PC00207 Angiogenesis#P00005>FGF#P00213;FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000020754.4|UniProtKB=F6RD50 F6RD50 YTHDC1 PTHR12357:SF3 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING PROTEIN 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;nucleic acid binding#GO:0003676;protein-RNA adaptor activity#GO:0140517 regulation of mRNA metabolic process#GO:1903311;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;mRNA processing#GO:0006397;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA splicing#GO:0043484;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000014186.4|UniProtKB=A0A5F8H4K1 A0A5F8H4K1 CEP85 PTHR31075:SF3 CENTROSOMAL PROTEIN OF 85 KDA CENTROSOMAL PROTEIN OF 85 KDA intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000037587.1|UniProtKB=A0A5F8GL36 A0A5F8GL36 PTHR18934:SF83 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16 helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000020425.4|UniProtKB=A0A5F8G9Y3 A0A5F8G9Y3 TRHDE PTHR11533:SF294 PROTEASE M1 ZINC METALLOPROTEASE THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;exopeptidase activity#GO:0008238;metalloexopeptidase activity#GO:0008235;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 catabolic process#GO:0009056;primary metabolic process#GO:0044238;peptide catabolic process#GO:0043171;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000044359.1|UniProtKB=A0A5F8GA27 A0A5F8GA27 PTHR45893:SF5 POLYCOMB GROUP RING FINGER PROTEIN POLYCOMB GROUP RING FINGER PROTEIN 3 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558 PcG protein complex#GO:0031519;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000011396.5|UniProtKB=F6SNL9 F6SNL9 MAFA PTHR10129:SF30 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 hormone transport#GO:0009914;cellular process#GO:0009987;establishment of protein localization#GO:0045184;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;response to monosaccharide#GO:0034284;hormone secretion#GO:0046879;protein transport#GO:0015031;regulation of biological quality#GO:0065008;response to carbohydrate#GO:0009743;secretion by cell#GO:0032940;protein secretion#GO:0009306;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789;response to hexose#GO:0009746;signaling#GO:0023052;export from cell#GO:0140352;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;transport#GO:0006810;regulation of gene expression#GO:0010468;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;nitrogen compound transport#GO:0071705;regulation of metabolic process#GO:0019222;peptide transport#GO:0015833;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cell-cell signaling#GO:0007267;response to glucose#GO:0009749;insulin secretion#GO:0030073;regulation of nucleobase-containing compound metabolic process#GO:0019219;peptide secretion#GO:0002790;signal release#GO:0023061;regulation of RNA metabolic process#GO:0051252;peptide hormone secretion#GO:0030072;secretion#GO:0046903;regulation of DNA-templated transcription#GO:0006355;localization#GO:0051179;cell communication#GO:0007154;protein localization to extracellular region#GO:0071692;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000010971.4|UniProtKB=F7AQD7 F7AQD7 HERC1 PTHR22870:SF155 REGULATOR OF CHROMOSOME CONDENSATION E3 UBIQUITIN-PROTEIN LIGASE HERC1-RELATED guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000037278.1|UniProtKB=A0A5F8GPR9 A0A5F8GPR9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024261.2|UniProtKB=F6ZU25 F6ZU25 PTHR48018:SF55 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016437.4|UniProtKB=F7ARV9 F7ARV9 C4H1orf159 PTHR16247:SF0 RIKEN CDNA 9430015G10 GENE RIKEN CDNA 9430015G10 GENE MONDO|Ensembl=ENSMODG00000041211.1|UniProtKB=A0A5F8HFJ9 A0A5F8HFJ9 ASCL1 PTHR13935:SF153 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE FAMILY BHLH TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 sensory organ development#GO:0007423;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of neurogenesis#GO:0050767;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000019672.4|UniProtKB=F6TTW6 F6TTW6 MAST4 PTHR24356:SF224 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE_THREONINE-PROTEIN KINASE 4 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;signal transduction#GO:0007165;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000040864.1|UniProtKB=A0A5F8GYW5 A0A5F8GYW5 monDomV1R1291 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000041513.1|UniProtKB=A0A5F8H2U5 A0A5F8H2U5 PTHR14742:SF0 RIBONUCLEASE P SUBUNIT P21 RIBONUCLEASE P PROTEIN SUBUNIT P21 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;nucleolar ribonuclease P complex#GO:0005655;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;multimeric ribonuclease P complex#GO:0030681;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000043429.1|UniProtKB=A0A5F8GXY8 A0A5F8GXY8 LOC100618560 PTHR48002:SF105 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C12 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000044555.1|UniProtKB=A0A5F8H626 A0A5F8H626 PTHR37363:SF1 EKC/KEOPS COMPLEX SUBUNIT GON7 EKC_KEOPS COMPLEX SUBUNIT GON7 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000041166.1|UniProtKB=A0A5F8GC93 A0A5F8GC93 CMC4 PTHR15590:SF0 CX9C MOTIF-CONTAINING PROTEIN 4 CX9C MOTIF-CONTAINING PROTEIN 4 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000044680.1|UniProtKB=A0A5F8H3B7 A0A5F8H3B7 BNIP1 PTHR12825:SF0 BNIP1-RELATED VESICLE TRANSPORT PROTEIN SEC20 SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;transport#GO:0006810;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;SNARE complex#GO:0031201;organelle#GO:0043226;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000017906.4|UniProtKB=F7F334 F7F334 NCDN PTHR13109:SF8 NEUROCHONDRIN NEUROCHONDRIN animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;regulation of biological quality#GO:0065008;system development#GO:0048731;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of synaptic plasticity#GO:0048167;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of neuronal synaptic plasticity#GO:0048168;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007 dendritic tree#GO:0097447;neuron projection#GO:0043005;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000051228.1|UniProtKB=A0A5F8H587 A0A5F8H587 KMT5B PTHR12977:SF12 SUPPRESSOR OF VARIEGATION 4-20-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000005428.3|UniProtKB=F7D0S2 F7D0S2 DSTN PTHR11913:SF18 COFILIN-RELATED DESTRIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;protein-containing complex disassembly#GO:0032984;protein depolymerization#GO:0051261;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament depolymerization#GO:0030042;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;actin filament-based process#GO:0030029 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000004530.4|UniProtKB=F6UQ19 F6UQ19 ARL8B PTHR45732:SF13 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8B microtubule-based movement#GO:0007018;microtubule-based transport#GO:0099111;lysosomal transport#GO:0007041;axonal transport#GO:0098930;anterograde axonal transport#GO:0008089;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;axo-dendritic transport#GO:0008088;vesicle-mediated transport#GO:0016192;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;endosomal transport#GO:0016197;transport along microtubule#GO:0010970;establishment of localization#GO:0051234 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000028993.2|UniProtKB=K7E3H4 K7E3H4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000019961.3|UniProtKB=F6SRR0 F6SRR0 LOC100019556 PTHR48002:SF107 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020890.5|UniProtKB=H9H7Q4 H9H7Q4 HUWE1 PTHR11254:SF446 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HUWE1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 membrane organization#GO:0061024;nucleobase-containing compound metabolic process#GO:0006139;endomembrane system organization#GO:0010256;cellular process#GO:0009987;membrane fusion#GO:0061025;organelle organization#GO:0006996;response to stress#GO:0006950;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;response to stimulus#GO:0050896;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;Golgi organization#GO:0007030;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632 membrane#GO:0016020;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000018079.4|UniProtKB=F7FTT6 F7FTT6 GUCA1C PTHR23055:SF80 CALCIUM BINDING PROTEINS GUANYLYL CYCLASE-ACTIVATING PROTEIN 3 enzyme activator activity#GO:0008047;cyclase regulator activity#GO:0010851;molecular function regulator activity#GO:0098772;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;cation binding#GO:0043169;molecular function activator activity#GO:0140677 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000001204.4|UniProtKB=A0A5F8G6V3 A0A5F8G6V3 DNAJC6 PTHR23172:SF4 AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED AUXILIN binding#GO:0005488;clathrin binding#GO:0030276;protein binding#GO:0005515 protein-containing complex disassembly#GO:0032984;endocytosis#GO:0006897;clathrin-dependent endocytosis#GO:0072583;synaptic vesicle endocytosis#GO:0048488;cellular component organization#GO:0016043;localization#GO:0051179;cellular component disassembly#GO:0022411;cellular localization#GO:0051641;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;receptor-mediated endocytosis#GO:0006898;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;synaptic vesicle cycle#GO:0099504;transport#GO:0006810 postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;vesicle#GO:0031982;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000006823.4|UniProtKB=F6PGA0 F6PGA0 PTHR23086:SF26 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE TYPE-1 GAMMA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transferase#PC00220;kinase#PC00137 MONDO|Ensembl=ENSMODG00000000535.3|UniProtKB=F6XN12 F6XN12 PAK6 PTHR48015:SF19 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE PAK 6 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 response to stress#GO:0006950;response to nutrient levels#GO:0031667;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;regulation of MAPK cascade#GO:0043408;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837 MONDO|Ensembl=ENSMODG00000014079.4|UniProtKB=F6R4I5 F6R4I5 ACSL6 PTHR43272:SF54 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 6 ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;long-chain fatty acid metabolic process#GO:0001676;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 ligase#PC00142 MONDO|Ensembl=ENSMODG00000006921.4|UniProtKB=F6PRL9 F6PRL9 RCC1L PTHR46337:SF1 RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 ribonucleoprotein complex biogenesis#GO:0022613;mitochondrion organization#GO:0007005;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;cellular process#GO:0009987;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;cellular component biogenesis#GO:0044085;mitochondrial ribosome assembly#GO:0061668;cellular component organization or biogenesis#GO:0071840;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000000465.4|UniProtKB=F6URK7 F6URK7 ABCE1 PTHR19248:SF32 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY E MEMBER 1 nucleotide binding#GO:0000166;cation binding#GO:0043169;ribonucleoprotein complex binding#GO:0043021;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;iron ion binding#GO:0005506;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;metal ion binding#GO:0046872;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488 translational termination#GO:0006415;translation#GO:0006412;translational initiation#GO:0006413;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein biosynthetic process#GO:0160307;protein-containing complex disassembly#GO:0032984;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000023735.2|UniProtKB=F6X8V4 F6X8V4 PTHR14677:SF11 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED AN1-TYPE ZINC FINGER PROTEIN 2A protein metabolic process#GO:0019538;localization#GO:0051179;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein targeting#GO:0006605;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein targeting to ER#GO:0045047;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;establishment of protein localization to endoplasmic reticulum#GO:0072599;cellular process#GO:0009987;establishment of protein localization#GO:0045184 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000040086.1|UniProtKB=A0A5F8HJY8 A0A5F8HJY8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013765.4|UniProtKB=F6UB62 F6UB62 BCL7B PTHR12767:SF5 BCL7 RELATED B-CELL CLL_LYMPHOMA 7 PROTEIN FAMILY MEMBER B regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000044464.1|UniProtKB=K7E4U5 K7E4U5 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000012539.4|UniProtKB=F6SC37 F6SC37 LOC100024614 PTHR11461:SF157 SERINE PROTEASE INHIBITOR, SERPIN SERPIN A12 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000020307.4|UniProtKB=F7G7Q2 F7G7Q2 PTHR11477:SF1 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 1 transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000015324.4|UniProtKB=F6XXG5 F6XXG5 ERMP1 PTHR12147:SF22 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000001916.2|UniProtKB=F6W129 F6W129 RPL24 PTHR10792:SF1 60S RIBOSOMAL PROTEIN L24 LARGE RIBOSOMAL SUBUNIT PROTEIN EL24 structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000009748.4|UniProtKB=F6WTV5 F6WTV5 ISLR2 PTHR24366:SF173 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS IMMUNOGLOBULIN SUPERFAMILY CONTAINING LEUCINE RICH REPEAT 2 regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;regulation of neurogenesis#GO:0050767;regulation of growth#GO:0040008;regulation of nervous system development#GO:0051960;positive regulation of cell projection organization#GO:0031346;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;positive regulation of axonogenesis#GO:0050772;regulation of biological quality#GO:0065008;regulation of cell size#GO:0008361;positive regulation of growth#GO:0045927;positive regulation of cellular component organization#GO:0051130;regulation of cell growth#GO:0001558;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;positive regulation of cell growth#GO:0030307;regulation of anatomical structure morphogenesis#GO:0022603;regulation of axonogenesis#GO:0050770;regulation of anatomical structure size#GO:0090066;positive regulation of cell differentiation#GO:0045597 immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000004542.3|UniProtKB=F6U913 F6U913 FOXF1 PTHR46262:SF1 FORKHEAD BOX PROTEIN BINIOU FORKHEAD BOX PROTEIN F1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000007124.3|UniProtKB=F6SH88 F6SH88 RDH10 PTHR24322:SF755 PKSB RETINOL DEHYDROGENASE 10 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000025266.2|UniProtKB=F7ARC0 F7ARC0 LIPT1 PTHR12561:SF3 LIPOATE-PROTEIN LIGASE LIPOYL AMIDOTRANSFERASE LIPT1, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000042799.1|UniProtKB=A0A5F8G4S9 A0A5F8G4S9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000014087.4|UniProtKB=F6R4G6 F6R4G6 PTHR15608:SF0 SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2 17S U2 SNRNP COMPLEX COMPONENT HTATSF1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin-protein adaptor activity#GO:0140463;RNA binding#GO:0003723 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;localization#GO:0051179;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245 U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;site of double-strand break#GO:0035861;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;chromosome#GO:0005694;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000029062.2|UniProtKB=K7E263 K7E263 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000021502.4|UniProtKB=F7CRB3 F7CRB3 LAMA3 PTHR10574:SF285 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-3 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;tissue development#GO:0009888;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 MONDO|Ensembl=ENSMODG00000025501.3|UniProtKB=F6QYC4 F6QYC4 CFAP107 PTHR31180:SF2 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 107-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 107 cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoplasmic microtubule#GO:0005881;axoneme#GO:0005930;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000010510.5|UniProtKB=F6PRI7 F6PRI7 ZNF609 PTHR21564:SF2 BRAKELESS PROTEIN ZINC FINGER PROTEIN 609 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000009084.3|UniProtKB=F7FQU4 F7FQU4 OR51E2 PTHR26450:SF92 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51E2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002842.5|UniProtKB=F7EIR1 F7EIR1 SEMA6D PTHR11036:SF65 SEMAPHORIN SEMAPHORIN-6D signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000038932.1|UniProtKB=A0A5F8GSB0 A0A5F8GSB0 PTHR10075:SF118 BASIGIN RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000000841.2|UniProtKB=F6RPP2 F6RPP2 YJU2 PTHR12111:SF1 SPLICING FACTOR YJU2 SPLICING FACTOR YJU2 intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000013754.4|UniProtKB=F6WS39 F6WS39 FKBP6 PTHR46674:SF1 INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6 INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6 Hsp90 protein binding#GO:0051879;heat shock protein binding#GO:0031072;binding#GO:0005488;protein binding#GO:0005515 spermatogenesis#GO:0007283;regulatory ncRNA-mediated gene silencing#GO:0031047;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;male gamete generation#GO:0048232;sexual reproduction#GO:0019953;piRNA processing#GO:0034587;multicellular organismal reproductive process#GO:0048609;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000006688.3|UniProtKB=F7FFG1 F7FFG1 CNN1 PTHR47385:SF12 CALPONIN CALPONIN-1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000047922.1|UniProtKB=A0A5F8HKP4 A0A5F8HKP4 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000000840.4|UniProtKB=F7C2S4 F7C2S4 GABRA5 PTHR18945:SF23 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-5 transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023 animal gross anatomical part developmental process#GO:0160108;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789;synapse assembly#GO:0007416;signaling#GO:0023052;chloride transport#GO:0006821;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;cellular component assembly#GO:0022607;nervous system development#GO:0007399;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;anatomical structure development#GO:0048856;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;localization#GO:0051179;system development#GO:0048731;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;signaling receptor complex#GO:0043235;neuron projection membrane#GO:0032589;cell junction#GO:0030054;postsynapse#GO:0098794;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;leading edge membrane#GO:0031256;dendritic tree#GO:0097447;dendrite#GO:0030425;cell projection membrane#GO:0031253 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000028591.2|UniProtKB=K7E4P2 K7E4P2 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000025200.3|UniProtKB=F7CJM5 F7CJM5 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000019874.3|UniProtKB=F6RQQ0 F6RQQ0 PRDM11 PTHR46880:SF11 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN PR_SET DOMAIN 11 MONDO|Ensembl=ENSMODG00000016351.4|UniProtKB=A0A5F8GJ47 A0A5F8GJ47 PCDH15 PTHR24028:SF11 CADHERIN-87A PROTOCADHERIN-15 cellular process#GO:0009987;sensory perception of light stimulus#GO:0050953;multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;visual perception#GO:0007601;nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;cell adhesion#GO:0007155;system process#GO:0003008 plasma membrane#GO:0005886;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000050640.1|UniProtKB=A0A5F8HFG5 A0A5F8HFG5 LOC107649056 PTHR12471:SF2 VACUOLAR ATP SYNTHASE SUBUNIT S1 V-TYPE PROTON ATPASE SUBUNIT S1 regulation of pH#GO:0006885;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;regulation of intracellular pH#GO:0051453;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;biological regulation#GO:0065007;homeostatic process#GO:0042592 ATPase complex#GO:1904949;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;ATPase dependent transmembrane transport complex#GO:0098533;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation-transporting ATPase complex#GO:0090533;membrane#GO:0016020;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000004702.4|UniProtKB=F6TQ70 F6TQ70 ANKRD37 PTHR24201:SF0 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 37 protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 MONDO|Ensembl=ENSMODG00000005445.3|UniProtKB=F7D0F7 F7D0F7 PTHR47507:SF4 BARRIER TO AUTOINTEGRATION FACTOR 2 BARRIER-TO-AUTOINTEGRATION FACTOR-LIKE PROTEIN DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000006383.4|UniProtKB=F7G2G0 F7G2G0 STK10 PTHR48012:SF31 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE 10 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 regulation of cell migration#GO:0030334;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of cell motility#GO:2000145;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of lymphocyte migration#GO:2000401;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of leukocyte migration#GO:0002685;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000005940.3|UniProtKB=F6WW62 F6WW62 TRUB2 PTHR13195:SF0 PSEUDOURIDINE SYNTHASE-RELATED PSEUDOURIDYLATE SYNTHASE TRUB2, MITOCHONDRIAL isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;positive regulation of biosynthetic process#GO:0009891;macromolecule modification#GO:0043412;positive regulation of translation#GO:0045727;positive regulation of macromolecule metabolic process#GO:0010604;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;metabolic process#GO:0008152;mRNA metabolic process#GO:0016071;mRNA modification#GO:0016556;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;positive regulation of protein metabolic process#GO:0051247 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739 lyase#PC00144 MONDO|Ensembl=ENSMODG00000049086.1|UniProtKB=A0A5F8GX62 A0A5F8GX62 KCNJ8 PTHR11767:SF11 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 8 channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215 inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000043765.1|UniProtKB=A0A5F8HGY9 A0A5F8HGY9 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000006672.4|UniProtKB=F7FTB5 F7FTB5 ECSIT PTHR13113:SF1 ECSIT EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAYS EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAY, MITOCHONDRIAL regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to biotic stimulus#GO:0002831;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to external biotic stimulus#GO:0043207;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;toll-like receptor 4 signaling pathway#GO:0034142;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;immune response#GO:0006955;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune system process#GO:0002376;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>ECSIT#P01349 MONDO|Ensembl=ENSMODG00000024585.3|UniProtKB=F6PG72 F6PG72 PTHR24377:SF980 IP01015P-RELATED ZINC FINGER PROTEIN 420 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020832.4|UniProtKB=F6RL84 F6RL84 SMG9 PTHR14270:SF0 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071 MONDO|Ensembl=ENSMODG00000000212.4|UniProtKB=F6SZP7 F6SZP7 SPINT1 PTHR46750:SF1 KUNITZ-TYPE PROTEASE INHIBITOR 1 KUNITZ-TYPE PROTEASE INHIBITOR 1 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234 epidermis development#GO:0008544;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;cellular process#GO:0009987;epithelium development#GO:0060429;tissue development#GO:0009888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000010256.4|UniProtKB=F6W5M3 F6W5M3 PRELID2 PTHR11158:SF20 MSF1/PX19 RELATED PRELI DOMAIN-CONTAINING PROTEIN 2 lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 lipid localization#GO:0010876;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;macromolecule localization#GO:0033036;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;phospholipid transport#GO:0015914 intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000047993.1|UniProtKB=A0A5F8H4Z9 A0A5F8H4Z9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000020776.2|UniProtKB=F6Z9L3 F6Z9L3 GPAT3 PTHR23063:SF10 PHOSPHOLIPID ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 3 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 acyltransferase#PC00042;transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000042240.1|UniProtKB=A0A5F8GJ59 A0A5F8GJ59 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000017033.4|UniProtKB=A0A5F8GHB7 A0A5F8GHB7 ASH1L PTHR46147:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE ASH1 HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;histone H3K4 methyltransferase activity#GO:0042800;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000013846.3|UniProtKB=F6X673 F6X673 LIMK1 PTHR46485:SF7 LIM DOMAIN KINASE 1 LIM DOMAIN KINASE 1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 positive regulation of cellular component organization#GO:0051130;actin filament-based process#GO:0030029;positive regulation of organelle organization#GO:0010638;regulation of actin filament bundle assembly#GO:0032231;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;positive regulation of actin filament bundle assembly#GO:0032233;organelle organization#GO:0006996;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of cellular component biogenesis#GO:0044089;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956 nucleus#GO:0005634;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Cytoskeletal regulation by Rho GTPase#P00016>LIMK#P00524 MONDO|Ensembl=ENSMODG00000025663.3|UniProtKB=F6XDH7 F6XDH7 PTHR48482:SF4 INTERLEUKIN-19-RELATED INTERLEUKIN-24 cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000016387.4|UniProtKB=F7E9H3 F7E9H3 SALL4 PTHR23233:SF19 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 4 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000011826.4|UniProtKB=F7GM12 F7GM12 GLMN PTHR15430:SF2 GLOMULIN GLOMULIN enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of catabolic process#GO:0009894;vasculature development#GO:0001944;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;developmental process#GO:0032502;vasculogenesis#GO:0001570;regulation of proteasomal protein catabolic process#GO:0061136;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of protein catabolic process#GO:0042176;animal gross anatomical part developmental process#GO:0160108;regulation of macromolecule metabolic process#GO:0060255;circulatory system development#GO:0072359;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000001210.4|UniProtKB=A0A5F8HFK1 A0A5F8HFK1 ETNK2 PTHR22603:SF94 CHOLINE/ETHANOALAMINE KINASE ETHANOLAMINE KINASE 2 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137 MONDO|Ensembl=ENSMODG00000003907.4|UniProtKB=A0A5F8GAG8 A0A5F8GAG8 ZFYVE27 PTHR14543:SF1 PROTRUDIN PROTRUDIN positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;positive regulation of growth#GO:0045927;cellular response to growth factor stimulus#GO:0071363;positive regulation of axonogenesis#GO:0050772;regulation of cell size#GO:0008361;regulation of cellular component size#GO:0032535;regulation of multicellular organismal development#GO:2000026;protein localization to membrane#GO:0072657;response to endogenous stimulus#GO:0009719;cellular component organization#GO:0016043;signaling#GO:0023052;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cellular response to endogenous stimulus#GO:0071495;cell surface receptor signaling pathway#GO:0007166;regulation of axonogenesis#GO:0050770;regulation of multicellular organismal process#GO:0051239;regulation of cell growth#GO:0001558;cellular component assembly#GO:0022607;system development#GO:0048731;cell communication#GO:0007154;localization#GO:0051179;regulation of nervous system development#GO:0051960;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of growth#GO:0040008;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;developmental process#GO:0032502;intracellular protein localization#GO:0008104;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;plasma membrane bounded cell projection organization#GO:0120036;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;neuron development#GO:0048666;cellular localization#GO:0051641;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;endoplasmic reticulum organization#GO:0007029;cell development#GO:0048468;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;neuron differentiation#GO:0030182;positive regulation of cell differentiation#GO:0045597;protein localization to cell periphery#GO:1990778;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of cell growth#GO:0030307;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;neuron projection development#GO:0031175;endomembrane system organization#GO:0010256;nervous system development#GO:0007399;positive regulation of cell development#GO:0010720;vesicle-mediated transport#GO:0016192;localization within membrane#GO:0051668;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cell projection organization#GO:0031346;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;protein localization to plasma membrane#GO:0072659;endoplasmic reticulum tubular network organization#GO:0071786;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of developmental process#GO:0051094;transport#GO:0006810;regulation of cell differentiation#GO:0045595;regulation of cell projection organization#GO:0031344;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 intracellular membrane-bounded organelle#GO:0043231;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;growth cone#GO:0030426;axon#GO:0030424;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;endoplasmic reticulum tubular network#GO:0071782;neuron projection#GO:0043005;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000001192.4|UniProtKB=F7GHA9 F7GHA9 SOX13 PTHR45789:SF4 FI18025P1 TRANSCRIPTION FACTOR SOX-13 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000019881.4|UniProtKB=F6WL04 F6WL04 CRY2 PTHR11455:SF15 CRYPTOCHROME CRYPTOCHROME-2 carbon-carbon lyase activity#GO:0016830;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;lyase activity#GO:0016829;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;deoxyribodipyrimidine photo-lyase activity#GO:0003904;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 negative regulation of biological process#GO:0048519;response to abiotic stimulus#GO:0009628;circadian regulation of gene expression#GO:0032922;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;rhythmic process#GO:0048511;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;response to light stimulus#GO:0009416;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of circadian rhythm#GO:0042752;negative regulation of macromolecule metabolic process#GO:0010605;response to radiation#GO:0009314;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;photoperiodism#GO:0009648;regulation of biosynthetic process#GO:0009889;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 DNA photolyase#PC00014 Circadian clock system#P00015>Cry#P00505;Circadian clock system#P00015>cry#G01501;Circadian clock system#P00015>cry#G01497 MONDO|Ensembl=ENSMODG00000008807.3|UniProtKB=F6QB03 F6QB03 PTHR26454:SF155 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000044445.1|UniProtKB=A0A5F8HAA9 A0A5F8HAA9 RNF144B PTHR11685:SF104 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF144B catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000020180.3|UniProtKB=F7GHV8 F7GHV8 PTHR15298:SF4 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000038591.1|UniProtKB=A0A5F8HCU8 A0A5F8HCU8 PEX11A PTHR12652:SF22 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11A organelle organization#GO:0006996;cellular component organization#GO:0016043;peroxisome organization#GO:0007031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000019730.2|UniProtKB=F6X4R7 F6X4R7 LHFPL2 PTHR12489:SF19 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 2 PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004251.6|UniProtKB=F6TWG1 F6TWG1 ZC3H18 PTHR46582:SF1 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 MONDO|Ensembl=ENSMODG00000039193.1|UniProtKB=A0A5F8G5L7 A0A5F8G5L7 PTHR46501:SF2 MYOMEGALIN MYOMEGALIN microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;centrosome cycle#GO:0007098;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;Golgi apparatus#GO:0005794;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000050021.1|UniProtKB=A0A5F8GLV0 A0A5F8GLV0 PTHR11255:SF32 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;signal transduction#GO:0007165;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;biological regulation#GO:0065007;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;neutral lipid metabolic process#GO:0006638;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 kinase#PC00137;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000008486.2|UniProtKB=F7G461 F7G461 CYP1B1 PTHR24299:SF11 CYTOCHROME P450 FAMILY 1 CYTOCHROME P450 1B1 oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;steroid catabolic process#GO:0006706;regulation of biological quality#GO:0065008;estrogen metabolic process#GO:0008210;cellular process#GO:0009987;lipid catabolic process#GO:0016042;cellular response to xenobiotic stimulus#GO:0071466;biological regulation#GO:0065007;steroid metabolic process#GO:0008202;hormone metabolic process#GO:0042445;response to chemical#GO:0042221;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;secondary metabolic process#GO:0019748 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000046501.1|UniProtKB=A0A5F8HBU1 A0A5F8HBU1 PTHR46811:SF1 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000006988.4|UniProtKB=A0A5F8GWZ5 A0A5F8GWZ5 NDUFAF6 PTHR21181:SF13 ER membrane protein complex subunit 5-related NADH DEHYDROGENASE (UBIQUINONE) COMPLEX I, ASSEMBLY FACTOR 6 MONDO|Ensembl=ENSMODG00000024005.1|UniProtKB=F7A4B3 F7A4B3 RHOG PTHR24072:SF158 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOG hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817 regulation of biological quality#GO:0065008;Rac protein signal transduction#GO:0016601;establishment or maintenance of cell polarity#GO:0007163;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;regulation of actin cytoskeleton organization#GO:0032956;intracellular signaling cassette#GO:0141124;cytoskeleton organization#GO:0007010;taxis#GO:0042330;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;intracellular signal transduction#GO:0035556;supramolecular fiber organization#GO:0097435;cell chemotaxis#GO:0060326;cell communication#GO:0007154;actin filament-based process#GO:0030029;chemotaxis#GO:0006935;cortical cytoskeleton organization#GO:0030865;locomotion#GO:0040011;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;cellular response to stimulus#GO:0051716;response to external stimulus#GO:0009605;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cell migration#GO:0016477 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 G-protein#PC00020;small GTPase#PC00208 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Huntington disease#P00029>Rac#P00775;EGF receptor signaling pathway#P00018>Rac#P00564 MONDO|Ensembl=ENSMODG00000011924.2|UniProtKB=F7DZJ0 F7DZJ0 ENOPH1 PTHR20371:SF1 ENOLASE-PHOSPHATASE E1 ENOLASE-PHOSPHATASE E1 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000012162.4|UniProtKB=F7CYK0 F7CYK0 CEBPA PTHR23334:SF5 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN ALPHA transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000006889.4|UniProtKB=F6PVP3 F6PVP3 DCAF4 PTHR44472:SF5 DDB1- AND CUL4-ASSOCIATED FACTOR 4-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 4 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 MONDO|Ensembl=ENSMODG00000043137.1|UniProtKB=A0A5F8GR79 A0A5F8GR79 PTHR23268:SF92 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 3-1 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000018651.4|UniProtKB=F7B1W6 F7B1W6 AMMECR1L PTHR13016:SF1 AMMECR1 HOMOLOG AMMECR1-LIKE PROTEIN intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000027486.1|UniProtKB=K7DZ33 K7DZ33 PTHR10424:SF82 VIRAL ENVELOPE PROTEIN ENVELOPE POLYPROTEIN syncytium formation by cell-cell fusion#GO:0000768;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;striated muscle cell differentiation#GO:0051146;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;cell differentiation#GO:0030154;muscle structure development#GO:0061061;myoblast fusion#GO:0007520;muscle cell differentiation#GO:0042692;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024564.1|UniProtKB=F7CDA3 F7CDA3 LOC100030261 PTHR26453:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G7 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011243.3|UniProtKB=F6RLX9 F6RLX9 ATP6V1B1 PTHR43389:SF1 V-TYPE PROTON ATPASE SUBUNIT B V-TYPE PROTON ATPASE SUBUNIT B, KIDNEY ISOFORM intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600 membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;apical part of cell#GO:0045177;proton-transporting two-sector ATPase complex#GO:0016469;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;apical plasma membrane#GO:0016324;cation-transporting ATPase complex#GO:0090533;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000000858.4|UniProtKB=F7D345 F7D345 SHD PTHR15127:SF33 HEAVYWEIGHT, ISOFORM A SH2 DOMAIN-CONTAINING ADAPTER PROTEIN D binding#GO:0005488;protein binding#GO:0005515 MONDO|Ensembl=ENSMODG00000009511.4|UniProtKB=A0A5F8GHA2 A0A5F8GHA2 OSBP2 PTHR10972:SF194 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN 2 small molecule binding#GO:0036094;binding#GO:0005488;sterol binding#GO:0032934;alcohol binding#GO:0043178;cholesterol binding#GO:0015485;lipid binding#GO:0008289;steroid binding#GO:0005496 cytosol#GO:0005829;membrane#GO:0016020;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000019413.4|UniProtKB=F6SYZ3 F6SYZ3 FBXL17 PTHR16134:SF18 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 17 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 cellular process#GO:0009987;response to radiation#GO:0009314;regulation of circadian rhythm#GO:0042752;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;photoperiodism#GO:0009648;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;response to external stimulus#GO:0009605;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;catabolic process#GO:0009056;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000040441.1|UniProtKB=A0A5F8G2H7 A0A5F8G2H7 PTHR23409:SF20 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 cellular process#GO:0009987;metabolic process#GO:0008152;biosynthetic process#GO:0009058 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 reductase#PC00198;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921;De novo purine biosynthesis#P02738>GDP reductase#P02909;p53 pathway#P00059>R2#G04692;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915 MONDO|Ensembl=ENSMODG00000022615.2|UniProtKB=H9H887 H9H887 PTHR31551:SF1 PRE-MRNA-SPLICING FACTOR CWF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 12 post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000005378.4|UniProtKB=F6YKN0 F6YKN0 HAPSTR1 PTHR31624:SF4 UPF0472 PROTEIN C16ORF72 HUWE1 ASSOCIATED PROTEIN MODIFYING STRESS RESPONSES MONDO|Ensembl=ENSMODG00000009245.4|UniProtKB=A0A5F8G5T3 A0A5F8G5T3 MPI PTHR10309:SF0 MANNOSE-6-PHOSPHATE ISOMERASE MANNOSE-6-PHOSPHATE ISOMERASE isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;isomerase#PC00135 Mannose metabolism#P02752>Mannose 6-P isomerase#P03017 MONDO|Ensembl=ENSMODG00000012820.4|UniProtKB=F7DY20 F7DY20 C16orf87 PTHR31101:SF3 UPF0547 PROTEIN C16ORF87 UPF0547 PROTEIN C16ORF87 MONDO|Ensembl=ENSMODG00000013190.4|UniProtKB=A0A5F8GS17 A0A5F8GS17 RASGRP4 PTHR23113:SF157 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 4 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 regulation of natural killer cell mediated immunity#GO:0002715;cellular response to stimulus#GO:0051716;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of natural killer cell mediated immunity#GO:0002717;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;cell communication#GO:0007154;positive regulation of innate immune response#GO:0045089;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of lymphocyte mediated immunity#GO:0002706;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;intracellular signaling cassette#GO:0141124;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>CalDAG-GEF#P00736 MONDO|Ensembl=ENSMODG00000003925.4|UniProtKB=F7GIZ0 F7GIZ0 FAM193A PTHR15109:SF2 AGAP004327-PA PROTEIN FAM193A MONDO|Ensembl=ENSMODG00000007948.4|UniProtKB=F7G196 F7G196 PTHR24376:SF38 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 544-RELATED gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000042057.1|UniProtKB=A0A5F8GPQ4 A0A5F8GPQ4 PTHR12391:SF10 ARP2/3 COMPLEX 21 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 cellular component organization#GO:0016043;organelle organization#GO:0006996;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 MONDO|Ensembl=ENSMODG00000037447.1|UniProtKB=F7FA97 F7FA97 PTHR45885:SF6 CELL DIVISION CYCLE 5-LIKE PROTEIN CELL DIVISION CYCLE 5-LIKE PROTEIN binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;regulation of transcription by RNA polymerase II#GO:0006357;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000007459.5|UniProtKB=F7DB09 F7DB09 MTR PTHR45833:SF1 METHIONINE SYNTHASE METHIONINE SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;aspartate family amino acid biosynthetic process#GO:0009067;sulfur compound metabolic process#GO:0006790;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;oxoacid metabolic process#GO:0043436;tetrahydrofolate metabolic process#GO:0046653;carboxylic acid biosynthetic process#GO:0046394;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 S-adenosylmethionine biosynthesis#P02773>Cobalamin-dependent homocysteine transmethylase#P03142;Formyltetrahydrofolate biosynthesis#P02743>Cobalamin dependent homocysteine transmethylase#P02953;Methionine biosynthesis#P02753>Homocysteine transmethylase#P03024 MONDO|Ensembl=ENSMODG00000008293.4|UniProtKB=F7FTZ9 F7FTZ9 TMCC3 PTHR17613:SF8 CEREBRAL PROTEIN-11-RELATED TRANSMEMBRANE AND COILED-COIL DOMAIN PROTEIN 3 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000007375.4|UniProtKB=F6W4W7 F6W4W7 LOC100015685 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005482.4|UniProtKB=A0A5F8H9U9 A0A5F8H9U9 PTHR31954:SF2 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;spermatid differentiation#GO:0048515;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000016254.2|UniProtKB=F7C1Y8 F7C1Y8 LOC100013504 PTHR26453:SF58 OLFACTORY RECEPTOR OLFACTORY RECEPTOR FAMILY 13 SUBFAMILY P MEMBER 9 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014305.4|UniProtKB=F6W4N1 F6W4N1 LOC100025547 PTHR14882:SF5 COILED-COIL DOMAIN-CONTAINING 74A COILED-COIL DOMAIN CONTAINING 74A MONDO|Ensembl=ENSMODG00000020548.4|UniProtKB=F7BBS1 F7BBS1 RFC1 PTHR23389:SF35 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 REPLICATION FACTOR C SUBUNIT 1 ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 DNA replication#P00017>RFC#P00529 MONDO|Ensembl=ENSMODG00000042982.1|UniProtKB=A0A5F8GYC3 A0A5F8GYC3 PTHR24394:SF20 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 42 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000028440.1|UniProtKB=K7E3A1 K7E3A1 PTHR10424:SF72 VIRAL ENVELOPE PROTEIN BC035947 PROTEIN-RELATED muscle structure development#GO:0061061;cell differentiation#GO:0030154;myoblast fusion#GO:0007520;cellular process#GO:0009987;muscle cell differentiation#GO:0042692;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;syncytium formation by cell-cell fusion#GO:0000768;striated muscle cell differentiation#GO:0051146;animal gross anatomical part developmental process#GO:0160108;cell-cell fusion#GO:0140253;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000028933.2|UniProtKB=K7E495 K7E495 ICAM1 PTHR13771:SF19 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 5 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cell adhesion mediated by integrin#GO:0033627;cell adhesion#GO:0007155;leukocyte cell-cell adhesion#GO:0007159;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000048124.1|UniProtKB=K7E4C0 K7E4C0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013448.4|UniProtKB=F7G9K5 F7G9K5 TMEM25 PTHR47224:SF1 TRANSMEMBRANE PROTEIN 25 TRANSMEMBRANE PROTEIN 25 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of system process#GO:0044057;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;modulation of chemical synaptic transmission#GO:0050804;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794 MONDO|Ensembl=ENSMODG00000040982.1|UniProtKB=A0A5F8G6P1 A0A5F8G6P1 DPT PTHR15040:SF2 DERMATOPONTIN-RELATED DERMATOPONTIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cell adhesion#GO:0007155;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;external encapsulating structure organization#GO:0045229 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000046918.1|UniProtKB=F6WZH2 F6WZH2 LOC100024343 PTHR26450:SF40 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56A3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024691.2|UniProtKB=F7FCY9 F7FCY9 PTHR16231:SF5 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 6 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to tumor necrosis factor#GO:0034612;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to peptide#GO:1901652;tumor necrosis factor-mediated signaling pathway#GO:0033209;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000014823.4|UniProtKB=F7D1Q3 F7D1Q3 VWA8 PTHR21610:SF9 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000049322.1|UniProtKB=A0A5F8G8Q0 A0A5F8G8Q0 PTHR47091:SF1 ALPHA-PROTEIN KINASE 2-RELATED ALPHA-PROTEIN KINASE 3 striated muscle cell differentiation#GO:0051146;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;cardiac muscle cell differentiation#GO:0055007;heart development#GO:0007507;multicellular organismal process#GO:0032501;tissue development#GO:0009888;cellular process#GO:0009987;muscle tissue development#GO:0060537;system development#GO:0048731;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;circulatory system development#GO:0072359;cell differentiation#GO:0030154;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000001592.3|UniProtKB=F7BBA8 F7BBA8 SPRY2 PTHR12365:SF8 SPROUTY PROTEIN SPROUTY HOMOLOG 2 protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of intracellular signal transduction#GO:1902532;regulation of Ras protein signal transduction#GO:0046578;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of response to stimulus#GO:0048585;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;negative regulation of signal transduction#GO:0009968;regulation of epidermal growth factor receptor signaling pathway#GO:0042058 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>SPRY#G01511;EGF receptor signaling pathway#P00018>Spry#P00541;FGF signaling pathway#P00021>Spry#P00626 MONDO|Ensembl=ENSMODG00000050324.1|UniProtKB=A0A5F8G6T9 A0A5F8G6T9 DNAJC8 PTHR15606:SF4 DNAJ HOMOLOG SUBFAMILY C MEMBER 8/LIPOPOLYSACCHARIDE SPECIFIC RESPONSE-7-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 8 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000050850.1|UniProtKB=A0A5F8G5N3 A0A5F8G5N3 NUDT16L1 PTHR31699:SF6 NUDIX T16 FAMILY MEMBER TUDOR-INTERACTING REPAIR REGULATOR PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;RNA binding#GO:0003723;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;snoRNA binding#GO:0030515;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000020366.3|UniProtKB=F7FJQ7 F7FJQ7 SDHAF2 PTHR12469:SF2 PROTEIN EMI5 HOMOLOG, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 2, MITOCHONDRIAL generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;energy derivation by oxidation of organic compounds#GO:0015980;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;electron transport chain#GO:0022900;tricarboxylic acid cycle#GO:0006099;mitochondrial respiratory chain complex II assembly#GO:0034553;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000014652.3|UniProtKB=A0A5F8GZ17 A0A5F8GZ17 PTHR11353:SF21 CHAPERONIN CHAPERONIN CONTAINING TCP1 SUBUNIT 6A-RELATED protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;cytosol#GO:0005829;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 chaperonin#PC00073 MONDO|Ensembl=ENSMODG00000011107.5|UniProtKB=F7BBR4 F7BBR4 PTHR13143:SF6 TETRATRICOPEPTIDE REPEAT PROTEIN 19 TETRATRICOPEPTIDE REPEAT PROTEIN 19, MITOCHONDRIAL mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex III assembly#GO:0034551;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866 MONDO|Ensembl=ENSMODG00000046870.1|UniProtKB=A0A5F8GR45 A0A5F8GR45 PSMB9 PTHR11599:SF50 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-9 catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;proteasome complex#GO:0000502 protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000015392.4|UniProtKB=A0A5F8HDI4 A0A5F8HDI4 FBXW8 PTHR19855:SF16 WD40 REPEAT PROTEIN 12, 37 F-BOX_WD REPEAT-CONTAINING PROTEIN 8 MONDO|Ensembl=ENSMODG00000012901.4|UniProtKB=F7GKY0 F7GKY0 IKZF3 PTHR24404:SF23 ZINC FINGER PROTEIN ZINC FINGER PROTEIN AIOLOS sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000012891.3|UniProtKB=F6Z184 F6Z184 HMGCL PTHR42738:SF1 HYDROXYMETHYLGLUTARYL-COA LYASE HYDROXYMETHYLGLUTARYL-COA LYASE, MITOCHONDRIAL carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;lyase activity#GO:0016829 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 lyase#PC00144 MONDO|Ensembl=ENSMODG00000039352.1|UniProtKB=A0A5F8GUK8 A0A5F8GUK8 PTHR22017:SF0 PHOTORECEPTOR CILIUM ACTIN REGULATOR PHOTORECEPTOR CILIUM ACTIN REGULATOR cellular component organization#GO:0016043;cell development#GO:0048468;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;cellular process#GO:0009987;macromolecule localization#GO:0033036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;intracellular protein localization#GO:0008104;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 photoreceptor inner segment#GO:0001917;cilium#GO:0005929;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;9+0 non-motile cilium#GO:0097731;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 MONDO|Ensembl=ENSMODG00000006847.4|UniProtKB=K7E1S2 K7E1S2 TTLL1 PTHR12241:SF31 TUBULIN POLYGLUTAMYLASE POLYGLUTAMYLASE COMPLEX SUBUNIT TTLL1 tubulin binding#GO:0015631;ligase activity#GO:0016874;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515 cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;sperm motility#GO:0097722;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;spermatid differentiation#GO:0048515;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;developmental process#GO:0032502;spermatogenesis#GO:0007283;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;cilium#GO:0005929;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000023945.2|UniProtKB=F6V652 F6V652 HSPA2 PTHR19375:SF382 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK-RELATED 70 KDA PROTEIN 2 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887 metabolic process#GO:0008152;protein refolding#GO:0042026;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072;Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 MONDO|Ensembl=ENSMODG00000014006.2|UniProtKB=F6VQU7 F6VQU7 PSENEN PTHR16318:SF1 GAMMA-SECRETASE SUBUNIT PEN-2 GAMMA-SECRETASE SUBUNIT PEN-2 cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 catalytic complex#GO:1902494;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 Alzheimer disease-amyloid secretase pathway#P00003>Pen-2#P00089;Alzheimer disease-presenilin pathway#P00004>Pen-2#P00149 MONDO|Ensembl=ENSMODG00000025013.3|UniProtKB=F6TBX7 F6TBX7 PTHR24103:SF676 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000012231.5|UniProtKB=F6Z6N0 F6Z6N0 SALL3 PTHR23233:SF46 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 3 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002674.3|UniProtKB=A0A5F8GRV7 A0A5F8GRV7 GALNT7 PTHR11675:SF68 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 7 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000015241.4|UniProtKB=F6UK46 F6UK46 ABHD5 PTHR42886:SF34 RE40534P-RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE ABHD5 hydrolase activity#GO:0016787;acyltransferase activity#GO:0016746;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of primary metabolic process#GO:0080090;organophosphate metabolic process#GO:0019637;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;positive regulation of metabolic process#GO:0009893;organophosphate biosynthetic process#GO:0090407;regulation of lipid metabolic process#GO:0019216;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;homeostatic process#GO:0042592;phospholipid metabolic process#GO:0006644;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;regulation of lipid catabolic process#GO:0050994 intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000041746.1|UniProtKB=A0A5F8GNV2 A0A5F8GNV2 PTHR14759:SF34 STOP PROTEIN MUCIN-LIKE DOMAIN-CONTAINING PROTEIN microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;localization#GO:0051179 Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;cytoskeleton#GO:0005856;cis-Golgi network#GO:0005801;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;microtubule#GO:0005874;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000013629.4|UniProtKB=F6UWQ9 F6UWQ9 NOSIP PTHR13063:SF10 ENOS INTERACTING PROTEIN NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000018980.4|UniProtKB=F7FP95 F7FP95 CUL9 PTHR22771:SF2 CULLIN AND GALACTOSE-BINDING DOMAIN-CONTAINING CULLIN-9 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of mitotic nuclear division#GO:0007088;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;primary metabolic process#GO:0044238 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 MONDO|Ensembl=ENSMODG00000018731.3|UniProtKB=F7EY66 F7EY66 PTHR26452:SF204 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003559.4|UniProtKB=F7GBC0 F7GBC0 ISCA1 PTHR10072:SF41 IRON-SULFUR CLUSTER ASSEMBLY PROTEIN IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;iron-sulfur cluster assembly#GO:0016226;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component assembly#GO:0022607;metabolic process#GO:0008152;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000043893.1|UniProtKB=A0A5F8G1P1 A0A5F8G1P1 PTHR26452:SF310 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013205.4|UniProtKB=F7EWH1 F7EWH1 PTHR22588:SF5 VWFA DOMAIN-CONTAINING PROTEIN COLLAGEN ALPHA-6(VI) CHAIN cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000045276.1|UniProtKB=F7F1Y1 F7F1Y1 LOC100030411 PTHR26452:SF99 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024154.2|UniProtKB=A0A5F8H0V5 A0A5F8H0V5 SPATA13 PTHR45834:SF5 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED SPERMATOGENESIS-ASSOCIATED PROTEIN 13 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;filopodium assembly#GO:0046847;cellular process#GO:0009987;cell projection assembly#GO:0030031;lamellipodium assembly#GO:0030032;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000044007.1|UniProtKB=A0A5F8GQZ8 A0A5F8GQZ8 PTHR17453:SF0 SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;protein-containing complex organization#GO:0043933;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599;cellular component assembly#GO:0022607;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein targeting#GO:0006605 signal recognition particle, endoplasmic reticulum targeting#GO:0005786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribonucleoprotein complex#GO:1990904 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000043940.1|UniProtKB=A0A5F8GN26 A0A5F8GN26 PTHR13619:SF0 PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;phosphatidylglycerol biosynthetic process#GO:0006655 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000012836.4|UniProtKB=F7DCJ7 F7DCJ7 USP49 PTHR21646:SF7 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 49 peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000016439.4|UniProtKB=F6XQT6 F6XQT6 CASS4 PTHR10654:SF19 CAS SCAFFOLDING PROTEIN CAS SCAFFOLDING PROTEIN FAMILY MEMBER 4 cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cell migration#GO:0016477;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000009380.3|UniProtKB=F7CPU4 F7CPU4 ATF4 PTHR13044:SF2 ACTIVATING TRANSCRIPTION FACTOR ATF 4/5 CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-4 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Apoptosis signaling pathway#P00006>ATF#P00302 MONDO|Ensembl=ENSMODG00000004087.4|UniProtKB=F6VVY2 F6VVY2 TMEM135 PTHR12459:SF27 TRANSMEMBRANE PROTEIN 135-RELATED TRANSMEMBRANE PROTEIN 135 MONDO|Ensembl=ENSMODG00000027580.2|UniProtKB=K7E4Q9 K7E4Q9 PTHR24373:SF390 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE RICH REPEAT CONTAINING 66 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000041861.1|UniProtKB=A0A5F8H4P9 A0A5F8H4P9 RPP25 PTHR13516:SF5 RIBONUCLEASE P SUBUNIT P25 RIBONUCLEASE P PROTEIN SUBUNIT P25 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 intracellular protein-containing complex#GO:0140535;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;ribonuclease MRP complex#GO:0000172 endoribonuclease#PC00094;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000041116.1|UniProtKB=A0A5F8G730 A0A5F8G730 FAM83B PTHR16181:SF31 PROTEIN FAM83A-RELATED PROTEIN FAM83B protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000008185.4|UniProtKB=F7E4E9 F7E4E9 MYOCD PTHR22793:SF11 MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED MYOCARDIN anatomical structure development#GO:0048856;system development#GO:0048731;muscle tissue development#GO:0060537;animal gross anatomical part developmental process#GO:0160108;muscle structure development#GO:0061061;cell differentiation#GO:0030154;circulatory system development#GO:0072359;muscle cell differentiation#GO:0042692;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869;animal organ development#GO:0048513;multicellular organism development#GO:0007275;striated muscle cell differentiation#GO:0051146;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;tissue development#GO:0009888;multicellular organismal process#GO:0032501;heart development#GO:0007507;cardiac muscle cell differentiation#GO:0055007;cellular process#GO:0009987 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000010038.4|UniProtKB=F7D817 F7D817 GLOD4 PTHR46466:SF1 GLYOXALASE DOMAIN-CONTAINING PROTEIN 4 GLYOXALASE DOMAIN-CONTAINING PROTEIN 4 MONDO|Ensembl=ENSMODG00000010050.4|UniProtKB=F6TT75 F6TT75 SLAMF8 PTHR12080:SF92 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE SLAM FAMILY MEMBER 8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;immune response#GO:0006955;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;immune system process#GO:0002376;cell communication#GO:0007154 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000008662.3|UniProtKB=K7E1H5 K7E1H5 AQP9 PTHR43829:SF6 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-9 passive transmembrane transporter activity#GO:0022803;water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;carbohydrate transmembrane transporter activity#GO:0015144 carbohydrate transport#GO:0008643;transport#GO:0006810;water transport#GO:0006833;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850;fluid transport#GO:0042044;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219 membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000049502.1|UniProtKB=A0A5F8G1P5 A0A5F8G1P5 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000013432.4|UniProtKB=F7GIN5 F7GIN5 ARCN1 PTHR10121:SF0 COATOMER SUBUNIT DELTA COATOMER SUBUNIT DELTA protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;Golgi vesicle transport#GO:0048193;organelle localization#GO:0051640;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization in cell#GO:0051649 intracellular organelle#GO:0043229;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;COPI-coated vesicle#GO:0030137;cytoplasm#GO:0005737;vesicle coat#GO:0030120 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000001149.5|UniProtKB=A0A5F8GW79 A0A5F8GW79 CPEB2 PTHR12566:SF8 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 2 protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;translation regulator activity#GO:0045182;mRNA 3'-UTR binding#GO:0003730;translation factor activity#GO:0180051 negative regulation of translation#GO:0017148;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 neuron projection#GO:0043005;nucleus#GO:0005634;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000043233.1|UniProtKB=A0A5F8G3R6 A0A5F8G3R6 PTHR12015:SF183 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 26-RELATED chemotaxis#GO:0006935;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;cell chemotaxis#GO:0060326;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;cell motility#GO:0048870;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;leukocyte migration#GO:0050900;leukocyte chemotaxis#GO:0030595;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;cellular process#GO:0009987;cell migration#GO:0016477;granulocyte migration#GO:0097530;response to chemical#GO:0042221;taxis#GO:0042330 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000000485.4|UniProtKB=F6UA59 F6UA59 IPO9 PTHR10997:SF9 IMPORTIN-7, 8, 11 IMPORTIN-9 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 nucleus#GO:0005634;cytosol#GO:0005829;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 MONDO|Ensembl=ENSMODG00000015103.3|UniProtKB=A0A5F8GUX3 A0A5F8GUX3 OSTN PTHR35353:SF1 OSTEOCRIN OSTEOCRIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000006279.4|UniProtKB=F7FDM2 F7FDM2 PCDH20 PTHR24028:SF260 CADHERIN-87A PROTOCADHERIN-20 cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000009837.4|UniProtKB=F6WAZ8 F6WAZ8 TBC1D21 PTHR22957:SF489 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 21 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000025438.2|UniProtKB=F6S5K7 F6S5K7 PTHR31345:SF3 CENTROMERE PROTEIN Q CENTROMERE PROTEIN Q metaphase chromosome alignment#GO:0051310;organelle localization#GO:0051640;chromosome segregation#GO:0007059;localization#GO:0051179;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;cell cycle process#GO:0022402;cellular process#GO:0009987;chromosome localization#GO:0050000 membraneless organelle#GO:0043228;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000020811.4|UniProtKB=F6S792 F6S792 PTHR45739:SF1 MATRIX PROTEIN, PUTATIVE-RELATED EXTRACELLULAR MATRIX ORGANIZING PROTEIN FRAS1 cell-substrate adhesion#GO:0031589;multicellular organismal-level homeostasis#GO:0048871;tissue homeostasis#GO:0001894;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;homeostatic process#GO:0042592;epithelial structure maintenance#GO:0010669;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000008364.4|UniProtKB=F7E490 F7E490 EIF4G2 PTHR23253:SF9 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 2 RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;translation factor activity#GO:0180051 translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000016040.4|UniProtKB=A0A5F8GHV6 A0A5F8GHV6 NRCAM PTHR10075:SF44 BASIGIN RELATED NEURONAL CELL ADHESION MOLECULE cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000021028.4|UniProtKB=A0A5F8G6S9 A0A5F8G6S9 CBS PTHR10314:SF194 CYSTATHIONINE BETA-SYNTHASE CYSTATHIONINE BETA-SYNTHASE hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 lyase#PC00144;metabolite interconversion enzyme#PC00262 Cysteine biosynthesis#P02737>O-Acetylserine-lyase#P02887 MONDO|Ensembl=ENSMODG00000014320.4|UniProtKB=A0A5F8GK54 A0A5F8GK54 MYO1G PTHR13140:SF381 MYOSIN UNCONVENTIONAL MYOSIN-IG macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 cytoskeleton organization#GO:0007010;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;actin filament-based movement#GO:0030048;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000018412.4|UniProtKB=F6XV26 F6XV26 PTHR10876:SF7 ZINC FINGER PROTEIN ZPR1 ZINC FINGER PROTEIN ZPR1 binding#GO:0005488;protein binding#GO:0005515 biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000012256.4|UniProtKB=F6YGR8 F6YGR8 SLC7A9 PTHR11785:SF354 AMINO ACID TRANSPORTER B(0,+)-TYPE AMINO ACID TRANSPORTER 1 amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;L-amino acid transmembrane transporter activity#GO:0015179 organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 MONDO|Ensembl=ENSMODG00000014081.4|UniProtKB=F6R4Z2 F6R4Z2 STRA8 PTHR35254:SF1 STIMULATED BY RETINOIC ACID GENE 8 PROTEIN HOMOLOG STIMULATED BY RETINOIC ACID GENE 8 PROTEIN HOMOLOG MONDO|Ensembl=ENSMODG00000008217.4|UniProtKB=F6ZYF3 F6ZYF3 PTHR24304:SF0 CYTOCHROME P450 FAMILY 7 CYTOCHROME P450 7B1 oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824 monocarboxylic acid biosynthetic process#GO:0072330;cholesterol homeostasis#GO:0042632;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;homeostatic process#GO:0042592;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;carboxylic acid metabolic process#GO:0019752 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000018545.3|UniProtKB=F7GD20 F7GD20 CGAS PTHR10656:SF35 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular response to stress#GO:0033554;regulation of DNA recombination#GO:0000018;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;regulation of DNA metabolic process#GO:0051052;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;regulation of double-strand break repair via homologous recombination#GO:0010569;negative regulation of double-strand break repair via homologous recombination#GO:2000042;positive regulation of response to external stimulus#GO:0032103;response to stress#GO:0006950;regulation of multicellular organismal process#GO:0051239;response to chemical#GO:0042221;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of response to biotic stimulus#GO:0002831;positive regulation of cytokine production#GO:0001819;regulation of response to stress#GO:0080134;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;positive regulation of innate immune response#GO:0045089;regulation of macromolecule biosynthetic process#GO:0010556;activation of innate immune response#GO:0002218;negative regulation of DNA metabolic process#GO:0051053;cellular response to nitrogen compound#GO:1901699;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to stimulus#GO:0050896;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of double-strand break repair#GO:2000779;cellular response to stimulus#GO:0051716;negative regulation of DNA recombination#GO:0045910;positive regulation of type I interferon production#GO:0032481;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;negative regulation of cellular process#GO:0048523;positive regulation of response to biotic stimulus#GO:0002833;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219 cytosol#GO:0005829;site of double-strand break#GO:0035861;chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;nucleotidyltransferase#PC00174 MONDO|Ensembl=ENSMODG00000004051.4|UniProtKB=A0A5F8GRW3 A0A5F8GRW3 FEZ1 PTHR12394:SF4 ZYGIN FASCICULATION AND ELONGATION PROTEIN ZETA-1 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;axon#GO:0030424 MONDO|Ensembl=ENSMODG00000013026.4|UniProtKB=F7BP25 F7BP25 TENT4B PTHR23092:SF51 POLY(A) RNA POLYMERASE TERMINAL NUCLEOTIDYLTRANSFERASE 4B adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000011691.4|UniProtKB=A0A5F8GHF7 A0A5F8GHF7 TAF7L PTHR12228:SF0 TRANSCRIPTION INITIATION FACTOR TFIID 55 KD SUBUNIT-RELATED TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 7 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367 RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 MONDO|Ensembl=ENSMODG00000046321.1|UniProtKB=F6QEI6 F6QEI6 PTHR19367:SF24 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 8-4 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000019676.4|UniProtKB=A0A5F8GRW2 A0A5F8GRW2 PTHR13258:SF0 SYNDETIN SYNDETIN binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515 cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;transport#GO:0006810;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;recycling endosome#GO:0055037;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 MONDO|Ensembl=ENSMODG00000023414.3|UniProtKB=F6Q4Q0 F6Q4Q0 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000008839.3|UniProtKB=F7CUW1 F7CUW1 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000048837.1|UniProtKB=F7B6C8 F7B6C8 LOC100030067 PTHR48018:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 974 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001147.3|UniProtKB=F7D3Z3 F7D3Z3 LOC100011415 PTHR26454:SF10 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6V1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018563.5|UniProtKB=F7G231 F7G231 SMAP1 PTHR45705:SF8 FI20236P1 STROMAL MEMBRANE-ASSOCIATED PROTEIN 1 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of endocytosis#GO:0030100;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000010639.3|UniProtKB=F7D4W8 F7D4W8 SRR PTHR43050:SF1 SERINE / THREONINE RACEMASE FAMILY MEMBER SERINE RACEMASE catalytic activity#GO:0003824;isomerase activity#GO:0016853;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;magnesium ion binding#GO:0000287;cation binding#GO:0043169;racemase and epimerase activity#GO:0016854;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;metal ion binding#GO:0046872;lyase activity#GO:0016829 amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 Isoleucine biosynthesis#P02748>Threonine dehydratase#P02995 MONDO|Ensembl=ENSMODG00000006788.3|UniProtKB=F6PH56 F6PH56 PDP2 PTHR13832:SF343 PROTEIN PHOSPHATASE 2C [PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 2, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000016127.4|UniProtKB=F7DSD8 F7DSD8 PTHR48112:SF36 HIGH MOBILITY GROUP PROTEIN DSP1 TRANSCRIPTION FACTOR A, MITOCHONDRIAL transcription regulator activity#GO:0140110 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;mitochondrial transcription#GO:0006390;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;chromatin remodeling#GO:0006338;DNA-templated transcription initiation#GO:0006352;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304 cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoid#GO:0009295;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrial nucleoid#GO:0042645;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000021295.3|UniProtKB=F7G3V1 F7G3V1 CCDC39 PTHR18962:SF0 COILED-COIL DOMAIN-CONTAINING PROTEIN 39 COILED-COIL DOMAIN-CONTAINING PROTEIN 39 cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;inner dynein arm assembly#GO:0036159;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based transport#GO:0099111;cilium movement#GO:0003341;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;determination of bilateral symmetry#GO:0009855;left/right pattern formation#GO:0060972;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;determination of left/right symmetry#GO:0007368;microtubule-based movement#GO:0007018;cell motility#GO:0048870;organelle assembly#GO:0070925;pattern specification process#GO:0007389;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;axoneme assembly#GO:0035082;regionalization#GO:0003002;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;specification of symmetry#GO:0009799;developmental process#GO:0032502;transport#GO:0006810;establishment of localization#GO:0051234 intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000012421.4|UniProtKB=F6PKI2 F6PKI2 SGO2 PTHR21577:SF3 SHUGOSHIN SHUGOSHIN 2 cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid cohesion#GO:0007064;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;meiotic sister chromatid cohesion#GO:0051177;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;cell cycle process#GO:0022402;cell cycle#GO:0007049;meiosis I#GO:0007127;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;reproductive process#GO:0022414;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;sister chromatid cohesion#GO:0007062;organelle fission#GO:0048285 intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793 centromere DNA-binding protein#PC00071 MONDO|Ensembl=ENSMODG00000003218.4|UniProtKB=F7EMR1 F7EMR1 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000008234.4|UniProtKB=F6ZXV5 F6ZXV5 ART1 PTHR10339:SF19 ADP-RIBOSYLTRANSFERASE GPI-LINKED NAD(P)(+)--ARGININE ADP-RIBOSYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 transferase#PC00220 MONDO|Ensembl=ENSMODG00000019444.4|UniProtKB=F6RXJ3 F6RXJ3 CTSH PTHR12411:SF1044 CYSTEINE PROTEASE FAMILY C1-RELATED PRO-CATHEPSIN H catalytic activity, acting on a protein#GO:0140096;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;enzyme activator activity#GO:0008047;peptidase activator activity#GO:0016504;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;molecular function activator activity#GO:0140677;peptidase regulator activity#GO:0061134 protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;proteolysis#GO:0006508;immune system process#GO:0002376;response to stimulus#GO:0050896;catabolic process#GO:0009056;zymogen activation#GO:0031638;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;biosynthetic process#GO:0009058;adaptive immune response#GO:0002250;protein maturation#GO:0051604;gene expression#GO:0010467;immune response#GO:0006955;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000015494.4|UniProtKB=F6WFD2 F6WFD2 PTHR15505:SF3 RIIA DOMAIN-CONTAINING PROTEIN 1 CILIOGENESIS-ASSOCIATED TTC17-INTERACTING PROTEIN cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cell projection organization#GO:0030030;actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cilium organization#GO:0044782 MONDO|Ensembl=ENSMODG00000011328.3|UniProtKB=A0A5F8H699 A0A5F8H699 HK2 PTHR19443:SF4 HEXOKINASE HEXOKINASE-2 hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824 ADP catabolic process#GO:0046032;purine nucleoside diphosphate catabolic process#GO:0009137;glucose homeostasis#GO:0042593;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;pyruvate metabolic process#GO:0006090;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;ADP metabolic process#GO:0046031;cellular homeostasis#GO:0019725;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate catabolic process#GO:1901292;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;oxoacid metabolic process#GO:0043436;intracellular glucose homeostasis#GO:0001678;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;ribonucleoside diphosphate metabolic process#GO:0009185;carbohydrate homeostasis#GO:0033500;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;intracellular chemical homeostasis#GO:0055082;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;catabolic process#GO:0009056;glucose 6-phosphate metabolic process#GO:0051156;nucleoside phosphate metabolic process#GO:0006753;homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975 cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytosol#GO:0005829;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;cytoplasmic side of membrane#GO:0098562;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;side of membrane#GO:0098552;outer membrane#GO:0019867;intracellular organelle#GO:0043229 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 Pentose phosphate pathway#P02762>Hexokinase#P03079;Fructose galactose metabolism#P02744>Hexokinase#P02966;Glycolysis#P00024>Hexokinase#P00677 MONDO|Ensembl=ENSMODG00000020394.4|UniProtKB=A0A5F8GA59 A0A5F8GA59 RAI14 PTHR24129:SF0 ANKYCORBIN ANKYCORBIN MONDO|Ensembl=ENSMODG00000007386.4|UniProtKB=F6ZMS8 F6ZMS8 CDH17 PTHR24027:SF419 CADHERIN-23 CADHERIN-17 beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cell migration#GO:0016477;cell motility#GO:0048870 extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000013317.4|UniProtKB=A0A5F8H787 A0A5F8H787 BTBD9 PTHR46306:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 9 BTB_POZ DOMAIN-CONTAINING PROTEIN 9 modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;regulation of biological process#GO:0050789;circadian rhythm#GO:0007623;rhythmic process#GO:0048511;regulation of signaling#GO:0023051 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000051571.1|UniProtKB=A0A5F8H3A3 A0A5F8H3A3 LOC100031136 PTHR24249:SF79 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 9 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000008701.3|UniProtKB=F6PWM3 F6PWM3 FZD3 PTHR11309:SF22 FRIZZLED FRIZZLED-3 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;protein binding#GO:0005515;molecular transducer activity#GO:0060089;Wnt-protein binding#GO:0017147 Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;non-canonical Wnt signaling pathway#GO:0035567;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>Frizzled#P00475;Angiogenesis#P00005>Fzd#P00189;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Angiogenesis#P00005>FRP#P00237;Wnt signaling pathway#P00057>Frizzled#P01428 MONDO|Ensembl=ENSMODG00000018447.4|UniProtKB=F7CUF9 F7CUF9 NRROS PTHR45617:SF7 LEUCINE RICH REPEAT FAMILY PROTEIN TRANSFORMING GROWTH FACTOR BETA ACTIVATOR LRRC33 cytokine binding#GO:0019955;growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488;transforming growth factor beta binding#GO:0050431 response to stimulus#GO:0050896;defense response#GO:0006952;response to stress#GO:0006950;immune system process#GO:0002376;immune response#GO:0006955;inflammatory response#GO:0006954 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000043522.1|UniProtKB=F7EYJ9 F7EYJ9 PTHR26450:SF46 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51F1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018525.4|UniProtKB=F7GL53 F7GL53 PTHR47048:SF1 PROTEIN SCAF11 PROTEIN SCAF11 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 MONDO|Ensembl=ENSMODG00000039521.1|UniProtKB=A0A5F8GII2 A0A5F8GII2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000012243.4|UniProtKB=F6YH73 F6YH73 FAAP24 PTHR31786:SF2 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 24 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 24 binding#GO:0005488;chromatin binding#GO:0003682 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Fanconi anaemia nuclear complex#GO:0043240;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000000747.3|UniProtKB=A0A5F8H935 A0A5F8H935 CAMKMT PTHR13539:SF3 CALMODULIN-LYSINE N-METHYLTRANSFERASE CALMODULIN-LYSINE N-METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000011192.3|UniProtKB=F6SRK5 F6SRK5 CTNNB1 PTHR45976:SF4 ARMADILLO SEGMENT POLARITY PROTEIN CATENIN BETA-1 cell adhesion molecule binding#GO:0050839;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712;protein phosphatase binding#GO:0019903;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902;DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515 cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cell adhesion#GO:0007155;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell adhesion#GO:0098609;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622 p53 pathway feedback loops 2#P04398>beta-catenin#P04670;CCKR signaling map#P06959>beta-catenin#P07150;Gonadotropin-releasing hormone receptor pathway#P06664>CTNNB1#P06838;Cadherin signaling pathway#P00012>betacatenin#P00463;Wnt signaling pathway#P00057>Beta-Catenin#P01432;Angiogenesis#P00005>beta catenin#P00187;Alzheimer disease-presenilin pathway#P00004>beta-catenin#P00156 MONDO|Ensembl=ENSMODG00000005626.4|UniProtKB=F7CFD6 F7CFD6 PAPPA2 PTHR46130:SF1 LAMGL DOMAIN-CONTAINING PROTEIN PAPPALYSIN-2 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000005349.5|UniProtKB=F6YLL9 F6YLL9 VPS16 PTHR12811:SF3 VACUOLAR PROTEIN SORTING VPS16 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;vacuole fusion, non-autophagic#GO:0042144;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;vacuole fusion#GO:0097576;vacuole organization#GO:0007033;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043 cytoplasm#GO:0005737;vacuole#GO:0005773;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;lysosomal membrane#GO:0005765;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle tethering complex#GO:0099023;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000012700.4|UniProtKB=F6UYA4 F6UYA4 LOC100617074 PTHR26452:SF729 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004550.4|UniProtKB=F6R5E9 F6R5E9 FAM118B PTHR28623:SF1 PROTEIN FAM118B PROTEIN FAM118B catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952 MONDO|Ensembl=ENSMODG00000012422.3|UniProtKB=F6PKH4 F6PKH4 LRTM1 PTHR24369:SF231 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000002676.4|UniProtKB=A0A5F8GU57 A0A5F8GU57 PTHR11738:SF199 MHC CLASS I NK CELL RECEPTOR IG-LIKE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000023932.2|UniProtKB=F7FLC0 F7FLC0 MICOS10 PTHR21304:SF0 MICOS COMPLEX SUBUNIT MIC10 MICOS COMPLEX SUBUNIT MIC10 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000007570.4|UniProtKB=F7FPI3 F7FPI3 NECAB1 PTHR12178:SF11 EF-HAND DOMAIN-CONTAINING PROTEIN N-TERMINAL EF-HAND CALCIUM-BINDING PROTEIN 1 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000045434.1|UniProtKB=A0A5F8GPJ3 A0A5F8GPJ3 RPS20 PTHR11700:SF8 30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US10 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000029480.2|UniProtKB=K7E3E9 K7E3E9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012668.3|UniProtKB=F6VXJ5 F6VXJ5 TAZ PTHR12497:SF8 TAZ PROTEIN TAFAZZIN TAFAZZIN acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;cellular component organization#GO:0016043;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycerophospholipid metabolic process#GO:0006650;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;organelle organization#GO:0006996;organophosphate metabolic process#GO:0019637;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000018222.3|UniProtKB=F6PGI7 F6PGI7 LRRC58 PTHR45752:SF13 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 58 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000002457.4|UniProtKB=F7DEG3 F7DEG3 ANKRD33B PTHR24173:SF1 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 33B scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000041865.1|UniProtKB=A0A5F8HI76 A0A5F8HI76 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000038383.1|UniProtKB=A0A5F8HKL9 A0A5F8HKL9 PTHR23349:SF10 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST CLASS A BASIC HELIX-LOOP-HELIX PROTEIN 9 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000046636.1|UniProtKB=A0A5F8GD49 A0A5F8GD49 SNORC PTHR28453:SF1 PROTEIN SNORC PROTEIN SNORC cellular anatomical structure#GO:0110165;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000024131.2|UniProtKB=F6XZA2 F6XZA2 PTHR23430:SF458 HISTONE H2A LATE HISTONE H2A.L3 structural molecule activity#GO:0005198 negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000009453.4|UniProtKB=F7FZJ8 F7FZJ8 PTHR14647:SF56 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSYLCERAMIDE SULFOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;biosynthetic process#GO:0009058;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;lipid biosynthetic process#GO:0008610;ceramide biosynthetic process#GO:0046513;developmental process#GO:0032502;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;myelination#GO:0042552;multicellular organism development#GO:0007275;carbohydrate derivative biosynthetic process#GO:1901137;primary metabolic process#GO:0044238;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;glycosphingolipid biosynthetic process#GO:0006688;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;glycolipid biosynthetic process#GO:0009247;ceramide metabolic process#GO:0006672;anatomical structure development#GO:0048856 transferase#PC00220 MONDO|Ensembl=ENSMODG00000021275.3|UniProtKB=F7DVK7 F7DVK7 SIAH2 PTHR45877:SF4 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;acyltransferase activity#GO:0016746;binding#GO:0005488;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 Wnt signaling pathway#P00057>SIAH-1#P01433 MONDO|Ensembl=ENSMODG00000000165.3|UniProtKB=F6XA88 F6XA88 ENDOD1 PTHR21472:SF8 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN MONDO|Ensembl=ENSMODG00000011565.4|UniProtKB=F6QBI1 F6QBI1 KLHDC2 PTHR46228:SF3 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000005481.4|UniProtKB=F7BXQ0 F7BXQ0 TNR PTHR19143:SF254 FIBRINOGEN/TENASCIN/ANGIOPOEITIN TENASCIN-R developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;nervous system development#GO:0007399;multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000038037.1|UniProtKB=A0A5F8GLR8 A0A5F8GLR8 PTHR18952:SF120 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 2 catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;biological regulation#GO:0065007;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801 membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 MONDO|Ensembl=ENSMODG00000009174.4|UniProtKB=F7ADF5 F7ADF5 TGS1 PTHR14741:SF32 S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED TRIMETHYLGUANOSINE SYNTHASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741 RNA methylation#GO:0001510;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000008493.3|UniProtKB=A0A5F8H7I9 A0A5F8H7I9 LOC100028625 PTHR10204:SF33 NAD P H OXIDOREDUCTASE-RELATED RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE] oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;oxidoreductase activity, acting on NAD(P)H#GO:0016651;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000005676.4|UniProtKB=A0A5F8G6J8 A0A5F8G6J8 PTHR10137:SF5 V-TYPE PROTON ATPASE SUBUNIT C V-TYPE PROTON ATPASE SUBUNIT C 1 ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;ATPase complex#GO:1904949;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;proton-transporting two-sector ATPase complex#GO:0016469;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000050975.1|UniProtKB=A0A5F8H9J1 A0A5F8H9J1 PTHR19343:SF13 T CELL RECEPTOR ALPHA VARIABLE 1-2 IG-LIKE DOMAIN-CONTAINING PROTEIN antigen binding#GO:0003823;peptide binding#GO:0042277;binding#GO:0005488 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000044175.1|UniProtKB=F7D993 F7D993 GZF2 PTHR24404:SF122 ZINC FINGER PROTEIN GDNF INDUCIBLE ZINC FINGER PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009304.4|UniProtKB=F6YX10 F6YX10 SLC17A6 PTHR11662:SF201 SOLUTE CARRIER FAMILY 17 VESICULAR GLUTAMATE TRANSPORTER 2 acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;trans-synaptic signaling#GO:0099537;regulation of biological quality#GO:0065008;localization#GO:0051179;cell communication#GO:0007154;regulation of synapse structure or activity#GO:0050803;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;vesicle-mediated transport#GO:0016192;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234 secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;presynapse#GO:0098793;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;cell junction#GO:0030054;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 secondary carrier transporter#PC00258 Ionotropic glutamate receptor pathway#P00037>Vglut#P01021 MONDO|Ensembl=ENSMODG00000007813.4|UniProtKB=A0A5F8H5X8 A0A5F8H5X8 FBF1 PTHR33689:SF1 FAS-BINDING FACTOR 1 FAS-BINDING FACTOR 1 cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriole#GO:0005814;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000001061.3|UniProtKB=F6YRE3 F6YRE3 PTHR24230:SF84 G-PROTEIN COUPLED RECEPTOR UROTENSIN-2 RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000050739.1|UniProtKB=K7E4H2 K7E4H2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007767.4|UniProtKB=F7AXE5 F7AXE5 KDM2A PTHR23123:SF3 PHD/F-BOX CONTAINING PROTEIN LYSINE-SPECIFIC DEMETHYLASE 2A histone modifying activity#GO:0140993;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;protein demethylase activity#GO:0140457;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000001519.4|UniProtKB=F7F462 F7F462 NSG1 PTHR28546:SF3 NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2-RELATED NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 metabolic process#GO:0008152;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;transport#GO:0006810;macromolecule metabolic process#GO:0043170;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031;regulation of biological quality#GO:0065008;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;biological regulation#GO:0065007 somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;late endosome#GO:0005770;glutamatergic synapse#GO:0098978;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;vesicle#GO:0031982;intracellular vesicle#GO:0097708;postsynapse#GO:0098794;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;endosome#GO:0005768;dendrite#GO:0030425;postsynaptic membrane#GO:0045211 MONDO|Ensembl=ENSMODG00000005833.3|UniProtKB=Q8HY33 Q8HY33 CA1 PTHR18952:SF282 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 1 lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000008561.4|UniProtKB=F7CXK5 F7CXK5 MRPL22 PTHR13501:SF10 CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL22M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000017321.3|UniProtKB=F6WVV2 F6WVV2 PTHR23168:SF0 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;cellular component organization#GO:0016043;negative regulation of cell cycle#GO:0045786;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;regulation of chromosome segregation#GO:0051983;cell cycle checkpoint signaling#GO:0000075;chromosome localization#GO:0050000;regulation of cell cycle process#GO:0010564;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic spindle assembly checkpoint signaling#GO:0007094;organelle fission#GO:0048285;cell communication#GO:0007154;localization#GO:0051179;intracellular signal transduction#GO:0035556;organelle localization#GO:0051640;negative regulation of chromosome organization#GO:2001251;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;negative regulation of cellular component organization#GO:0051129;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic metaphase chromosome alignment#GO:0007080;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;negative regulation of cell cycle process#GO:0010948;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;mitotic sister chromatid segregation#GO:0000070;regulation of mitotic cell cycle#GO:0007346;nuclear division#GO:0000280;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;negative regulation of cell cycle phase transition#GO:1901988;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;negative regulation of biological process#GO:0048519;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of chromosome segregation#GO:0051985;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of mitotic sister chromatid segregation#GO:0033047;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;regulation of cellular process#GO:0050794;negative regulation of organelle organization#GO:0010639;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;chromosome organization#GO:0051276;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007 membraneless organelle#GO:0043228;spindle#GO:0005819;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;nuclear envelope#GO:0005635;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;endomembrane system#GO:0012505;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;organelle envelope#GO:0031967;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000049132.1|UniProtKB=A0A5F8GJ83 A0A5F8GJ83 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000008392.4|UniProtKB=A0A5F8HE34 A0A5F8HE34 PTHR44981:SF3 PERICENTRIN-LIKE PROTEIN, ISOFORM F PERICENTRIN mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850 MONDO|Ensembl=ENSMODG00000008106.5|UniProtKB=F7G5U3 F7G5U3 ADRA2B PTHR24248:SF130 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-2B ADRENERGIC RECEPTOR cation binding#GO:0043169;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;G protein-coupled amine receptor activity#GO:0008227;hormone binding#GO:0042562 cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 MONDO|Ensembl=ENSMODG00000019907.4|UniProtKB=F6VQ80 F6VQ80 MADD PTHR13008:SF7 MAP-KINASE ACTIVATING DEATH DOMAIN PROTEIN MADD /DENN/AEX-3 C.ELEGANS MAP KINASE-ACTIVATING DEATH DOMAIN PROTEIN molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of apoptotic process#GO:0042981;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 Apoptosis signaling pathway#P00006>MADD#P00267 MONDO|Ensembl=ENSMODG00000001433.4|UniProtKB=F7BCE1 F7BCE1 PTHR11177:SF388 CHITINASE GH18 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568 chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000015003.4|UniProtKB=A0A5F8H041 A0A5F8H041 GRIA3 PTHR18966:SF151 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 3 gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834 synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;dendrite#GO:0030425;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;asymmetric synapse#GO:0032279;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351;neuron projection#GO:0043005;protein-containing complex#GO:0032991;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;dendritic spine#GO:0043197;postsynapse#GO:0098794;cell projection#GO:0042995;neuron spine#GO:0044309;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>Glu3#P01016 MONDO|Ensembl=ENSMODG00000006062.5|UniProtKB=A0A5F8GBH1 A0A5F8GBH1 AFDN PTHR10398:SF2 AFADIN AFADIN cytoskeletal adaptor activity#GO:0008093;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell junction organization#GO:0034330;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;adherens junction organization#GO:0034332;cellular process#GO:0009987;cell-cell junction maintenance#GO:0045217;cellular component organization or biogenesis#GO:0071840;cell adhesion#GO:0007155;cell-cell junction organization#GO:0045216 cell junction#GO:0030054;adherens junction#GO:0005912;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membrane#GO:0016020;cell-cell junction#GO:0005911;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 Alzheimer disease-presenilin pathway#P00004>Afadin#P00146 MONDO|Ensembl=ENSMODG00000006140.4|UniProtKB=F7BSX7 F7BSX7 GLYR1 PTHR43580:SF10 OXIDOREDUCTASE GLYR1-RELATED CYTOKINE-LIKE NUCLEAR FACTOR N-PAC nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;DNA binding#GO:0003677;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;biosynthetic process#GO:0009058;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;chromosome#GO:0005694 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000023184.2|UniProtKB=F7C4V0 F7C4V0 PTHR14386:SF2 PROTEIN FAM204A PROTEIN FAM204A MONDO|Ensembl=ENSMODG00000009836.4|UniProtKB=F6WAX6 F6WAX6 POLA2 PTHR23061:SF12 DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT DNA POLYMERASE ALPHA SUBUNIT B nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 replisome#GO:0030894;nuclear DNA-directed RNA polymerase complex#GO:0055029;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000048373.1|UniProtKB=A0A5F8GA55 A0A5F8GA55 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000047949.1|UniProtKB=A0A5F8HBG7 A0A5F8HBG7 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000041973.1|UniProtKB=F7G0W0 F7G0W0 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000044231.1|UniProtKB=A0A5F8G1R7 A0A5F8G1R7 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000041735.1|UniProtKB=A0A5F8GYN8 A0A5F8GYN8 STBD1 PTHR15048:SF1 STARCH-BINDING DOMAIN-CONTAINING PROTEIN 1 STARCH-BINDING DOMAIN-CONTAINING PROTEIN 1 process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052;localization#GO:0051179;cellular localization#GO:0051641;lysosomal transport#GO:0007041;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;glucan catabolic process#GO:0009251;catabolic process#GO:0009056;polysaccharide metabolic process#GO:0005976;polysaccharide catabolic process#GO:0000272;glycogen metabolic process#GO:0005977;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;vacuolar transport#GO:0007034;transport#GO:0006810;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular transport#GO:0046907;macroautophagy#GO:0016236;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;glycogen catabolic process#GO:0005980 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000022942.1|UniProtKB=F6PYS6 F6PYS6 LOC100020259 PTHR26450:SF411 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51A7 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021453.4|UniProtKB=A0A5F8H0F6 A0A5F8H0F6 PTPRM PTHR19134:SF206 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE MU phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;developmental process#GO:0032502;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000014422.3|UniProtKB=F7BH40 F7BH40 KDF1 PTHR35085:SF1 KERATINOCYTE DIFFERENTIATION FACTOR 1 KERATINOCYTE DIFFERENTIATION FACTOR 1 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell division#GO:0051302;regulation of biological process#GO:0050789 cell junction#GO:0030054;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000049050.1|UniProtKB=A0A5F8GDX8 A0A5F8GDX8 PTHR23149:SF9 G PATCH DOMAIN CONTAINING PROTEIN G PATCH DOMAIN-CONTAINING PROTEIN 4 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000008409.2|UniProtKB=A0A5F8GJQ7 A0A5F8GJQ7 PTHR23105:SF31 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER RIBOSOMAL L1 DOMAIN-CONTAINING PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000045262.1|UniProtKB=A0A5F8GB03 A0A5F8GB03 PTHR40141:SF2 3',5'-CYCLIC-AMP PHOSPHODIESTERASE-RELATED 3',5'-CYCLIC-AMP PHOSPHODIESTERASE MONDO|Ensembl=ENSMODG00000009027.4|UniProtKB=F7B2Y5 F7B2Y5 PSMG3 PTHR31051:SF1 PROTEASOME ASSEMBLY CHAPERONE 3 PROTEASOME ASSEMBLY CHAPERONE 3 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000017170.4|UniProtKB=F6QD47 F6QD47 PNPLA7 PTHR46042:SF1 DIPHTHINE METHYLTRANSFERASE DIPHTHINE METHYLTRANSFERASE macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000007617.4|UniProtKB=F7C597 F7C597 RSPH3 PTHR21648:SF0 FLAGELLAR RADIAL SPOKE PROTEIN 3 RADIAL SPOKE HEAD PROTEIN 3 HOMOLOG cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000015848.4|UniProtKB=F7F0F7 F7F0F7 VARS2 PTHR11946:SF71 VALYL-TRNA SYNTHETASES VALINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000045554.1|UniProtKB=F7AIL5 F7AIL5 OR10W1 PTHR26453:SF570 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003285.6|UniProtKB=A0A5F8HAU4 A0A5F8HAU4 LOXHD1 PTHR45901:SF8 PROTEIN CBG12474 LIPOXYGENASE HOMOLOGY DOMAIN-CONTAINING PROTEIN 1 sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;sensory perception of sound#GO:0007605;multicellular organismal process#GO:0032501 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;stereocilium#GO:0032420;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;membraneless organelle#GO:0043228;actin-based cell projection#GO:0098858;neuron projection#GO:0043005;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000016244.4|UniProtKB=A0A5F8G218 A0A5F8G218 ABI2 PTHR10460:SF26 ABL INTERACTOR FAMILY MEMBER ABL INTERACTOR 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell motility#GO:0048870;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell migration#GO:0016477;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869 cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;lamellipodium#GO:0030027;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;actin-based cell projection#GO:0098858;cell leading edge#GO:0031252;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019055.3|UniProtKB=F7AXX2 F7AXX2 CNOT7 PTHR10797:SF79 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 7 3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540 RNA catabolic process#GO:0006401;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139 CCR4-NOT complex#GO:0030014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000038610.1|UniProtKB=A0A5F8GEP2 A0A5F8GEP2 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000001121.3|UniProtKB=F7DP52 F7DP52 LOC100016555 PTHR15914:SF0 ALPHA-HEMOGLOBIN-STABILIZING PROTEIN ALPHA-HEMOGLOBIN-STABILIZING PROTEIN macromolecule metabolic process#GO:0043170;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871;protein stabilization#GO:0050821;metabolic process#GO:0008152;developmental process#GO:0032502;gene expression#GO:0010467;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;biosynthetic process#GO:0009058;hemopoiesis#GO:0030097;regulation of protein stability#GO:0031647;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;regulation of biological quality#GO:0065008;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;homeostatic process#GO:0042592;protein folding#GO:0006457;cell development#GO:0048468;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000004599.2|UniProtKB=F6QII1 F6QII1 C16orf74 PTHR37455:SF1 GENE, 27021-RELATED SIMILAR TO HUMAN CHROMOSOME 16 OPEN READING FRAME 74 multicellular organismal process#GO:0032501;multicellular organismal-level homeostasis#GO:0048871;homeostatic process#GO:0042592;temperature homeostasis#GO:0001659;adaptive thermogenesis#GO:1990845 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000014069.5|UniProtKB=A0A5F8H1Y0 A0A5F8H1Y0 ITPR3 PTHR13715:SF51 RYANODINE RECEPTOR AND IP3 RECEPTOR INOSITOL 1,4,5-TRISPHOSPHATE-GATED CALCIUM CHANNEL ITPR3 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;alcohol binding#GO:0043178;transporter activity#GO:0005215;metal ion binding#GO:0046872;ligand-gated calcium channel activity#GO:0099604;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;calcium ion binding#GO:0005509;gated channel activity#GO:0022836;monoatomic cation channel activity#GO:0005261;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;phosphatidylinositol binding#GO:0035091;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;cation binding#GO:0043169;channel activity#GO:0015267;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;ligand-gated monoatomic ion channel activity#GO:0015276 signal transduction#GO:0007165;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;calcium ion transmembrane transport#GO:0070588;signaling#GO:0023052;metal ion transport#GO:0030001;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186;monoatomic ion transport#GO:0006811;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085 endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;sarcoplasmic reticulum#GO:0016529;cell periphery#GO:0071944;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;vesicle#GO:0031982;organelle subcompartment#GO:0031984;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;sarcoplasm#GO:0016528;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 ion channel#PC00133;ligand-gated ion channel#PC00141 B cell activation#P00010>IP3R#P00398;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>IP3 channel#P00735;Gonadotropin-releasing hormone receptor pathway#P06664>IP3R#P06768;PDGF signaling pathway#P00047>IP3 receptor#P01160;Histamine H1 receptor mediated signaling pathway#P04385>IP3R#P04486;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IP3R#P00842;Endothelin signaling pathway#P00019>IP3 R#P00590;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>IP3R#P01064;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>IP3R#P05932;Wnt signaling pathway#P00057>IP3 Gated Calcium Channel#P01426 MONDO|Ensembl=ENSMODG00000019291.4|UniProtKB=F6RZE3 F6RZE3 SUPT6H PTHR10145:SF6 TRANSCRIPTION ELONGATION FACTOR SPT6 TRANSCRIPTION ELONGATION FACTOR SPT6 histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;biosynthetic process#GO:0009058;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000011191.3|UniProtKB=F6ZAF0 F6ZAF0 GFUS PTHR43238:SF1 GDP-L-FUCOSE SYNTHASE GDP-L-FUCOSE SYNTHASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000001974.3|UniProtKB=F6RIN5 F6RIN5 ZNF398 PTHR24390:SF240 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000006352.3|UniProtKB=F6ZRM0 F6ZRM0 CBFB PTHR10276:SF3 CORE-BINDING FACTOR, BETA SUBUNIT CORE-BINDING FACTOR SUBUNIT BETA transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription coactivator activity#GO:0003713 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000010069.2|UniProtKB=F6XNC7 F6XNC7 TIMM17B PTHR10485:SF2 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM17-B transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transmembrane protein transporter activity#GO:0008320 intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;mitochondrial transmembrane transport#GO:1990542;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;protein transport#GO:0015031;protein localization to mitochondrion#GO:0070585;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 transporter#PC00227 MONDO|Ensembl=ENSMODG00000012845.4|UniProtKB=F7CT32 F7CT32 DNAJA2 PTHR43888:SF31 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ HOMOLOG SUBFAMILY A MEMBER 2 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515;ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular response to heat#GO:0034605;response to heat#GO:0009408;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;protein refolding#GO:0042026;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;protein folding#GO:0006457 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000039576.1|UniProtKB=A0A5F8HJI4 A0A5F8HJI4 LOC100028875 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000047443.1|UniProtKB=A0A5F8GFT1 A0A5F8GFT1 PTHR23304:SF189 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000009684.4|UniProtKB=A0A5F8HA43 A0A5F8HA43 FTO PTHR31291:SF2 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO cellular response to stress#GO:0033554;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000043186.1|UniProtKB=A0A5F8GDY8 A0A5F8GDY8 MAP6 PTHR14759:SF29 STOP PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 6 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 regulation of neurogenesis#GO:0050767;regulation of cellular process#GO:0050794;positive regulation of cell projection organization#GO:0031346;regulation of microtubule-based process#GO:0032886;anatomical structure development#GO:0048856;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;regulation of cell differentiation#GO:0045595;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;positive regulation of developmental process#GO:0051094;intracellular transport#GO:0046907;regulation of cell projection organization#GO:0031344;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of multicellular organismal process#GO:0051240;regulation of organelle organization#GO:0033043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell development#GO:0048468;cell morphogenesis#GO:0000902;regulation of cellular component organization#GO:0051128;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;cellular localization#GO:0051641;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;positive regulation of cell development#GO:0010720;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell differentiation#GO:0045597;neuron differentiation#GO:0030182;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;dendrite morphogenesis#GO:0048813;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of cytoskeleton organization#GO:0051493;system development#GO:0048731;regulation of nervous system development#GO:0051960;localization#GO:0051179;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;regulation of multicellular organismal development#GO:2000026;cellular component organization#GO:0016043;cell differentiation#GO:0030154;positive regulation of nervous system development#GO:0051962;cell projection organization#GO:0030030;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;positive regulation of axonogenesis#GO:0050772;dendrite development#GO:0016358;regulation of multicellular organismal process#GO:0051239;regulation of microtubule cytoskeleton organization#GO:0070507;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of axonogenesis#GO:0050770;cell projection morphogenesis#GO:0048858 cytoskeleton#GO:0005856;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cis-Golgi network#GO:0005801;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;dendrite#GO:0030425;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;axon#GO:0030424;microtubule#GO:0005874;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 MONDO|Ensembl=ENSMODG00000012814.4|UniProtKB=F7DYM2 F7DYM2 PTPRC PTHR19134:SF539 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 protein phosphatase#PC00195;protein modifying enzyme#PC00260 T cell activation#P00053>CD45#P01329;B cell activation#P00010>CD45#P00396;JAK/STAT signaling pathway#P00038>PTP#P01033 MONDO|Ensembl=ENSMODG00000006646.4|UniProtKB=F7G424 F7G424 SLC2A4 PTHR23503:SF120 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 4 sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 response to oxygen-containing compound#GO:1901700;carbohydrate transport#GO:0008643;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;localization#GO:0051179;transmembrane transport#GO:0055085;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cellular response to peptide hormone stimulus#GO:0071375;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;import across plasma membrane#GO:0098739;cellular response to hormone stimulus#GO:0032870;vitamin transport#GO:0051180;transport#GO:0006810;cellular response to insulin stimulus#GO:0032869;establishment of localization#GO:0051234;import into cell#GO:0098657;D-glucose transmembrane transport#GO:1904659;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725;response to peptide hormone#GO:0043434;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;carbohydrate transmembrane transport#GO:0034219 intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000043948.1|UniProtKB=A0A5F8G6Q8 A0A5F8G6Q8 CD200 PTHR46841:SF3 OX-2 MEMBRANE GLYCOPROTEIN OX-2 MEMBRANE GLYCOPROTEIN binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;heterotypic cell-cell adhesion#GO:0034113;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;cell adhesion#GO:0007155;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cell body#GO:0044297;neuron projection#GO:0043005;axon#GO:0030424 MONDO|Ensembl=ENSMODG00000023995.2|UniProtKB=A0A5F8GE62 A0A5F8GE62 LOC100017995 PTHR13976:SF60 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484 intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000000148.4|UniProtKB=F6XT33 F6XT33 BPIFB1 PTHR47395:SF1 BPI FOLD-CONTAINING FAMILY B MEMBER 1 BPI FOLD-CONTAINING FAMILY B MEMBER 1 negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;response to other organism#GO:0051707;immune response#GO:0006955;regulation of innate immune response#GO:0045088;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;negative regulation of signal transduction#GO:0009968;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;immune system process#GO:0002376;regulation of signaling#GO:0023051 MONDO|Ensembl=ENSMODG00000001039.4|UniProtKB=F6ZEU9 F6ZEU9 DPP9 PTHR11731:SF109 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE 9 catalytic activity#GO:0003824;peptidase activity#GO:0008233;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000017527.4|UniProtKB=H9H734 H9H734 SBK2 PTHR48013:SF7 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED SERINE_THREONINE-PROTEIN KINASE SBK2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000004633.4|UniProtKB=F6VWY3 F6VWY3 DBN1 PTHR10829:SF1 CORTACTIN AND DREBRIN DREBRIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 regulation of cellular component size#GO:0032535;regulation of multicellular organismal development#GO:2000026;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;cell differentiation#GO:0030154;positive regulation of nervous system development#GO:0051962;cell projection organization#GO:0030030;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;regulation of synapse organization#GO:0050807;positive regulation of neuron projection development#GO:0010976;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of multicellular organismal process#GO:0051239;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;regulation of supramolecular fiber organization#GO:1902903;regulation of developmental process#GO:0050793;postsynapse organization#GO:0099173;positive regulation of neurogenesis#GO:0050769;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of dendrite development#GO:0050773;regulation of dendritic spine morphogenesis#GO:0061001;system development#GO:0048731;regulation of nervous system development#GO:0051960;regulation of actin filament organization#GO:0110053;regulation of actin polymerization or depolymerization#GO:0008064;plasma membrane bounded cell projection organization#GO:0120036;regulation of actin filament polymerization#GO:0030833;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of multicellular organismal process#GO:0051240;regulation of organelle organization#GO:0033043;regulation of postsynapse organization#GO:0099175;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;regulation of actin filament length#GO:0030832;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;neuron development#GO:0048666;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;nervous system development#GO:0007399;positive regulation of cell development#GO:0010720;neuron differentiation#GO:0030182;positive regulation of cell differentiation#GO:0045597;regulation of anatomical structure size#GO:0090066;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;regulation of dendrite morphogenesis#GO:0048814;regulation of neurogenesis#GO:0050767;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;synapse organization#GO:0050808;actin filament-based process#GO:0030029;positive regulation of cell projection organization#GO:0031346;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of developmental process#GO:0051094;neuron projection morphogenesis#GO:0048812;regulation of cell differentiation#GO:0045595;regulation of cell projection organization#GO:0031344;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035 dendrite#GO:0030425;dendritic tree#GO:0097447;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;postsynaptic membrane#GO:0045211;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;cortical cytoskeleton#GO:0030863;postsynapse#GO:0098794;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;cell projection#GO:0042995;synaptic membrane#GO:0097060;actin filament#GO:0005884;cell junction#GO:0030054;neuron projection#GO:0043005;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000051472.1|UniProtKB=A0A5F8GCJ3 A0A5F8GCJ3 PPTC7 PTHR12320:SF98 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE PTC7 HOMOLOG biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000016188.4|UniProtKB=A0A5F8GQA9 A0A5F8GQA9 UNKL PTHR14493:SF37 UNKEMPT FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE UNKL-RELATED MONDO|Ensembl=ENSMODG00000037001.1|UniProtKB=A0A5F8HJK2 A0A5F8HJK2 TMEM169 PTHR31777:SF0 TRANSMEMBRANE PROTEIN 169 TRANSMEMBRANE PROTEIN 169 MONDO|Ensembl=ENSMODG00000018421.4|UniProtKB=F6XUU8 F6XUU8 LRTM2 PTHR24369:SF221 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000008779.4|UniProtKB=A0A5F8GJX3 A0A5F8GJX3 ZNF541 PTHR16089:SF23 REST COREPRESSOR COREST PROTEIN-RELATED ZINC FINGER PROTEIN 541 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000019470.5|UniProtKB=F6RW47 F6RW47 SNX18 PTHR45827:SF4 SORTING NEXIN SORTING NEXIN-18 ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091 cellular localization#GO:0051641;localization#GO:0051179;plasma membrane organization#GO:0007009;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinetic process#GO:0032506;cytokinesis#GO:0000910;endocytosis#GO:0006897;cell cycle process#GO:0022402;cell division#GO:0051301;cellular component organization#GO:0016043;cell cycle#GO:0007049;endosomal transport#GO:0016197;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;membrane invagination#GO:0010324;intracellular transport#GO:0046907;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005238.4|UniProtKB=F6YNP0 F6YNP0 CAPN6 PTHR10183:SF440 CALPAIN CALPAIN 6 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000038053.1|UniProtKB=A0A5F8GNM8 A0A5F8GNM8 PCBD2 PTHR12599:SF15 PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE 2 lyase#PC00144;dehydratase#PC00091 MONDO|Ensembl=ENSMODG00000009229.5|UniProtKB=F7FZT3 F7FZT3 RHOBTB2 PTHR24072:SF137 RHO FAMILY GTPASE RHO-RELATED BTB DOMAIN-CONTAINING PROTEIN 2 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;protein binding#GO:0005515;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167 cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;regulation of actin filament-based process#GO:0032970;regulation of developmental process#GO:0050793;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;regulation of biological quality#GO:0065008;cell communication#GO:0007154;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;cortical cytoskeleton organization#GO:0030865 membrane#GO:0016020;cell periphery#GO:0071944;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000018870.4|UniProtKB=A0A5F8HHI4 A0A5F8HHI4 CD2AP PTHR14167:SF23 SH3 DOMAIN-CONTAINING CD2-ASSOCIATED PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;cell leading edge#GO:0031252;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000002078.4|UniProtKB=F6UZJ9 F6UZJ9 PTHR28674:SF1 SIMILAR TO DNA SEGMENT, CHR 10, WAYNE STATE UNIVERSITY 102,-EXPRESSED NOP PROTEIN CHAPERONE 1 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 protein-containing complex organization#GO:0043933;protein-RNA complex assembly#GO:0022618;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;ribonucleoprotein complex biogenesis#GO:0022613;cellular component assembly#GO:0022607 MONDO|Ensembl=ENSMODG00000003506.4|UniProtKB=A0A5F8HJW0 A0A5F8HJW0 DYM PTHR12895:SF9 DYMECLIN DYMECLIN cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Golgi organization#GO:0007030 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000012881.2|UniProtKB=F6ZP06 F6ZP06 PTHR43391:SF93 RETINOL DEHYDROGENASE-RELATED KETOREDUCTASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000008199.4|UniProtKB=F7DJ58 F7DJ58 PANK4 PTHR12280:SF42 PANTOTHENATE KINASE 4'-PHOSPHOPANTETHEINE PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphotransferase activity, alcohol group as acceptor#GO:0016773 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 kinase#PC00137;metabolite interconversion enzyme#PC00262 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 MONDO|Ensembl=ENSMODG00000003351.4|UniProtKB=F6ZQ18 F6ZQ18 DUS1L PTHR11082:SF5 TRNA-DIHYDROURIDINE SYNTHASE TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000012439.4|UniProtKB=F6PJH2 F6PJH2 CDK5RAP3 PTHR14894:SF0 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 biological regulation#GO:0065007;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to unfolded protein#GO:0006986;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000017153.4|UniProtKB=F6QE42 F6QE42 ERMAP PTHR24100:SF46 BUTYROPHILIN ERYTHROID MEMBRANE-ASSOCIATED PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;immune system process#GO:0002376;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000017078.4|UniProtKB=F6VKV2 F6VKV2 SNRNP40 PTHR44006:SF1 U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 mRNA splicing#P00058>U5#P01474 MONDO|Ensembl=ENSMODG00000017766.4|UniProtKB=A0A5F8GGM5 A0A5F8GGM5 TBC1D32 PTHR13465:SF3 UPF0183 PROTEIN PROTEIN BROAD-MINDED plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 MONDO|Ensembl=ENSMODG00000020831.3|UniProtKB=F6RL94 F6RL94 PTHR10624:SF9 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR-RELATED LY6_PLAUR DOMAIN-CONTAINING PROTEIN 5 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002570.2|UniProtKB=F7GF94 F7GF94 POLR2H PTHR10917:SF0 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;RNA polymerase III complex#GO:0005666;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 MONDO|Ensembl=ENSMODG00000049909.1|UniProtKB=F7D756 F7D756 ANGPTL4 PTHR19143:SF256 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 4 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857 chemical homeostasis#GO:0048878;lipid homeostasis#GO:0055088;triglyceride homeostasis#GO:0070328;homeostatic process#GO:0042592 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000048234.1|UniProtKB=M9MMI8 M9MMI8 PTHR44427:SF13 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 4-RELATED cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000017639.3|UniProtKB=F6Z4K4 F6Z4K4 CRKL PTHR19969:SF23 SH2-SH3 ADAPTOR PROTEIN-RELATED CRK-LIKE PROTEIN protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;kinase binding#GO:0019900;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090 regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;positive regulation of MAPK cascade#GO:0043410;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cell migration#GO:0016477;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;signaling#GO:0023052 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Crk#P00207;Integrin signalling pathway#P00034>Crk#P00933 MONDO|Ensembl=ENSMODG00000010463.4|UniProtKB=F7BL05 F7BL05 SMC3 PTHR43977:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 MONDO|Ensembl=ENSMODG00000040233.1|UniProtKB=F6U4B6 F6U4B6 PTHR19367:SF18 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 18 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000007332.3|UniProtKB=F7EEX8 F7EEX8 PTHR14974:SF3 SIMILAR TO RIKEN CDNA 1700025G04 GENE SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 21 MONDO|Ensembl=ENSMODG00000009132.3|UniProtKB=F7EY12 F7EY12 CTSW PTHR12411:SF101 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN W peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000013403.5|UniProtKB=F7D7V1 F7D7V1 FUZ PTHR13559:SF1 INTRACELLULAR TRAFFIC PROTEIN-RELATED PROTEIN FUZZY HOMOLOG cilium organization#GO:0044782;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 MONDO|Ensembl=ENSMODG00000000750.3|UniProtKB=F6T8K7 F6T8K7 EEF2 PTHR42908:SF35 TRANSLATION ELONGATION FACTOR-RELATED ELONGATION FACTOR 2 protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;ribonucleoprotein complex#GO:1990904 translation elongation factor#PC00222 MONDO|Ensembl=ENSMODG00000050530.1|UniProtKB=A0A5F8H6R7 A0A5F8H6R7 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000027596.2|UniProtKB=F6U166 F6U166 VSIG1 PTHR44974:SF1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 1 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000023496.2|UniProtKB=F7EGS9 F7EGS9 LOC100011074 PTHR26452:SF222 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6B2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000006798.4|UniProtKB=F6PGY7 F6PGY7 PCGF5 PTHR45893:SF6 POLYCOMB GROUP RING FINGER PROTEIN POLYCOMB GROUP RING FINGER PROTEIN 5 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;PcG protein complex#GO:0031519;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000006323.4|UniProtKB=F7B3I8 F7B3I8 TAS1R3 PTHR24061:SF435 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 3 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;system process#GO:0003008;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023790.2|UniProtKB=F6W920 F6W920 PTHR31943:SF1 INTERLEUKIN-28 AND 29 INTERFERON LAMBDA-2-RELATED molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;defense response to virus#GO:0051607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to virus#GO:0009615;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083;interleukin superfamily#PC00128;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000043405.1|UniProtKB=A0A5F8G7X0 A0A5F8G7X0 PTHR48018:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007456.4|UniProtKB=F6S0F1 F6S0F1 CLCA1 PTHR10579:SF52 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1 monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;chloride channel activity#GO:0005254;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000002398.4|UniProtKB=F7EZT1 F7EZT1 PDHB PTHR11624:SF116 DEHYDROGENASE RELATED PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;aerobic respiration#GO:0009060;acetyl-CoA metabolic process#GO:0006084;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;pyruvate metabolic process#GO:0006090;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521 catalytic complex#GO:1902494;transferase complex#GO:1990234;oxidoreductase complex#GO:1990204;acetyltransferase complex#GO:1902493;protein-containing complex#GO:0032991 oxidoreductase#PC00176;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000017813.4|UniProtKB=F6ZXY2 F6ZXY2 MRPS15 PTHR46685:SF1 28S RIBOSOMAL PROTEIN S15, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN US15M ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000015041.4|UniProtKB=F7G5C5 F7G5C5 OCEL1 PTHR23288:SF15 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL OCCLUDIN_ELL DOMAIN-CONTAINING PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;transcription by RNA polymerase II#GO:0006366;cell-cell junction organization#GO:0045216;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of macromolecule metabolic process#GO:0060255;DNA-templated transcription#GO:0006351;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of DNA-templated transcription#GO:0006355;snRNA metabolic process#GO:0016073;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;cell-cell junction assembly#GO:0007043;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of transcription by RNA polymerase II#GO:0006357;snRNA transcription#GO:0009301;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;nucleic acid biosynthetic process#GO:0141187 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708;vesicle#GO:0031982;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;apical junction complex#GO:0043296;apical part of cell#GO:0045177;tight junction#GO:0070160;nuclear protein-containing complex#GO:0140513;cell junction#GO:0030054;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;cell-cell junction#GO:0005911;cell periphery#GO:0071944;nucleus#GO:0005634;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;bicellular tight junction#GO:0005923;cytoplasm#GO:0005737;plasma membrane#GO:0005886 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000013795.3|UniProtKB=F6TE21 F6TE21 IL36RN PTHR10078:SF32 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-36 RECEPTOR ANTAGONIST PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125 cellular response to molecule of bacterial origin#GO:0071219;defense response#GO:0006952;response to external stimulus#GO:0009605;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;response to bacterium#GO:0009617;inflammatory response#GO:0006954;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;response to lipopolysaccharide#GO:0032496;cell surface receptor signaling pathway#GO:0007166;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;response to peptide#GO:1901652;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to molecule of bacterial origin#GO:0002237;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interleukin superfamily#PC00128;cytokine#PC00083;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000000685.2|UniProtKB=F6WM76 F6WM76 PTHR23268:SF24 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 16 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000048005.1|UniProtKB=F6RST0 F6RST0 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED RETROVIRAL ENVELOPE PROTEIN GP41-LIKE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001570.4|UniProtKB=F7BX33 F7BX33 METTL23 PTHR14614:SF167 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN HISTONE-ARGININE METHYLTRANSFERASE METTL23 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 epigenetic regulation of gene expression#GO:0040029;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000046866.1|UniProtKB=A0A5F8GNT7 A0A5F8GNT7 LOC130458235 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015899.4|UniProtKB=F7AGF9 F7AGF9 TMEM168 PTHR14437:SF2 TRANSMEMBRANE PROTEIN 168 TRANSMEMBRANE PROTEIN 168 MONDO|Ensembl=ENSMODG00000013232.4|UniProtKB=F7ECX4 F7ECX4 CBL PTHR23007:SF5 CBL E3 UBIQUITIN-PROTEIN LIGASE CBL transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;receptor tyrosine kinase binding#GO:0030971;acyltransferase activity#GO:0016746;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;ubiquitin-like protein transferase activity#GO:0019787 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of signal transduction#GO:0009968;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane raft#GO:0045121;membrane#GO:0016020;cell periphery#GO:0071944;membrane microdomain#GO:0098857;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ligase#PC00142 EGF receptor signaling pathway#P00018>c-Cbl#P00544 MONDO|Ensembl=ENSMODG00000002801.4|UniProtKB=A0A5F8HHY5 A0A5F8HHY5 SMC5 PTHR45916:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5 DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488 DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;condensed chromosome#GO:0000793 MONDO|Ensembl=ENSMODG00000004122.5|UniProtKB=A0A5F8GWR5 A0A5F8GWR5 PIEZO1 PTHR13167:SF40 PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261 detection of mechanical stimulus#GO:0050982;regulation of biological quality#GO:0065008;response to external stimulus#GO:0009605;regulation of membrane potential#GO:0042391;cellular response to abiotic stimulus#GO:0071214;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606;biological regulation#GO:0065007;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000037281.1|UniProtKB=A0A5F8GFJ1 A0A5F8GFJ1 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014049.3|UniProtKB=H9H6N1 H9H6N1 CCDC106 PTHR16477:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 106 COILED-COIL DOMAIN-CONTAINING PROTEIN 106 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000036982.1|UniProtKB=A0A5F8G700 A0A5F8G700 PTHR26453:SF156 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011864.4|UniProtKB=F7G318 F7G318 MPP2 PTHR23122:SF35 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 2 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000001668.4|UniProtKB=F6SQS9 F6SQS9 RNF40 PTHR23163:SF4 RING FINGER PROTEIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE BRE1B acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000043992.1|UniProtKB=A0A5F8HA33 A0A5F8HA33 PTHR11467:SF181 HISTONE H1 HISTONE H1.9-RELATED protein-containing complex binding#GO:0044877;double-stranded DNA binding#GO:0003690;nucleosome binding#GO:0031491;DNA binding#GO:0003677;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490 organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of DNA recombination#GO:0045910;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA recombination#GO:0000018;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000045323.1|UniProtKB=A0A5F8G460 A0A5F8G460 PTHR10252:SF153 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED CHROMATIN ACCESSIBILITY COMPLEX PROTEIN 1 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA-templated DNA replication#GO:0006261;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;DNA replication#GO:0006260;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;chromatin remodeling#GO:0006338;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325 chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;ISWI-type complex#GO:0031010;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000009886.4|UniProtKB=F6VCY4 F6VCY4 PALS1 PTHR23122:SF14 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PROTEIN PALS1 protein localization to cell periphery#GO:1990778;developmental process#GO:0032502;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;morphogenesis of an epithelium#GO:0002009;neurogenesis#GO:0022008;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;nervous system development#GO:0007399;embryo development#GO:0009790;establishment or maintenance of apical/basal cell polarity#GO:0035088;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of bipolar cell polarity#GO:0061245;localization within membrane#GO:0051668;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;cellular localization#GO:0051641;tissue morphogenesis#GO:0048729;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;system development#GO:0048731;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000024466.2|UniProtKB=A0A5F8H2M0 A0A5F8H2M0 FXYD6 PTHR14132:SF15 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 6-RELATED ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of transmembrane transport#GO:0034762;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000015717.3|UniProtKB=F7B5W7 F7B5W7 TMEM219 PTHR16002:SF6 TRANSMEMBRANE PROTEIN 248-LIKE INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 3 RECEPTOR MONDO|Ensembl=ENSMODG00000044443.1|UniProtKB=A0A5F8GYU4 A0A5F8GYU4 WNT1 PTHR12027:SF91 WNT RELATED PROTO-ONCOGENE WNT-1 cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell fate commitment#GO:0045165;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;anatomical structure development#GO:0048856;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 MONDO|Ensembl=ENSMODG00000020584.5|UniProtKB=A0A5F8GG08 A0A5F8GG08 ZZEF1 PTHR22772:SF4 NOVEL ZZ TYPE ZINC FINGER DOMAIN CONTAINING PROTEIN ZINC FINGER ZZ-TYPE AND EF-HAND DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000047695.1|UniProtKB=A0A5F8HIV7 A0A5F8HIV7 PTHR46479:SF1 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;organelle localization#GO:0051640;transport#GO:0006810;vesicle-mediated transport#GO:0016192;lysosome localization#GO:0032418;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;BLOC-1 complex#GO:0031083;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000005664.4|UniProtKB=F6VL05 F6VL05 NOC3L PTHR14428:SF5 NUCLEOLAR COMPLEX PROTEIN 3 NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG chromatin binding#GO:0003682;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000023342.2|UniProtKB=F6U8P7 F6U8P7 DOLK PTHR13205:SF15 TRANSMEMBRANE PROTEIN 15-RELATED DOLICHOL KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000005272.3|UniProtKB=F7D557 F7D557 PTHR24393:SF100 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 345-RELATED nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000012745.5|UniProtKB=A0A5F8HGY4 A0A5F8HGY4 ZNF526 PTHR24388:SF105 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 526 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000003799.4|UniProtKB=F6ZK49 F6ZK49 VEGFC PTHR12025:SF3 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR C signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;positive regulation of response to external stimulus#GO:0032103;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of response to external stimulus#GO:0032101;sprouting angiogenesis#GO:0002040;animal gross anatomical part developmental process#GO:0160108;angiogenesis#GO:0001525;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;vascular endothelial growth factor receptor signaling pathway#GO:0048010;blood vessel morphogenesis#GO:0048514;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;response to hypoxia#GO:0001666;positive regulation of locomotion#GO:0040017;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295;regulation of locomotion#GO:0040012;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;positive regulation of chemotaxis#GO:0050921;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;regulation of leukocyte migration#GO:0002685;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000041057.1|UniProtKB=A0A5F8GKW9 A0A5F8GKW9 SPATA31F1 PTHR21859:SF12 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31D1 MONDO|Ensembl=ENSMODG00000025140.1|UniProtKB=F7D570 F7D570 TMEM215 PTHR31922:SF2 TRANSMEMBRANE PROTEIN 215 TRANSMEMBRANE PROTEIN 215 MONDO|Ensembl=ENSMODG00000007542.4|UniProtKB=A0A5F8H954 A0A5F8H954 PTHR10971:SF36 MRNA EXPORT FACTOR AND BUB3 MITOTIC CHECKPOINT PROTEIN BUB3 protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488 signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of sister chromatid segregation#GO:0033046;negative regulation of cell cycle#GO:0045786;regulation of chromosome segregation#GO:0051983;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of chromosome segregation#GO:0051985;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular process#GO:0050794;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;negative regulation of chromosome organization#GO:2001251;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;kinetochore#GO:0000776;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000049696.1|UniProtKB=F6Q4N9 F6Q4N9 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000031964.2|UniProtKB=A0A5F8HEH9 A0A5F8HEH9 PTHR46880:SF6 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 385C MONDO|Ensembl=ENSMODG00000007347.3|UniProtKB=F7B0D5 F7B0D5 LOC100618441 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019084.4|UniProtKB=F7FNE1 F7FNE1 UTP3 PTHR13237:SF8 SOMETHING ABOUT SILENCING PROTEIN 10-RELATED SOMETHING ABOUT SILENCING PROTEIN 10 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000015558.4|UniProtKB=F7AJG0 F7AJG0 ATP2A1 PTHR42861:SF24 CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC_ENDOPLASMIC RETICULUM CALCIUM ATPASE 1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;homeostatic process#GO:0042592;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873 membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000015088.4|UniProtKB=F7F3I0 F7F3I0 CLDN16 PTHR12002:SF56 CLAUDIN CLAUDIN-16 paracellular tight junction channel activity#GO:0160187;transporter activity#GO:0005215 cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;paracellular transport#GO:0160184;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;transport#GO:0006810 apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000003450.4|UniProtKB=F7DWT3 F7DWT3 PTHR20961:SF148 GLYCOSYLTRANSFERASE EGF DOMAIN-SPECIFIC O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000044977.1|UniProtKB=A0A5F8GIB2 A0A5F8GIB2 PTHR11783:SF9 SULFOTRANSFERASE SULT SULFOTRANSFERASE 2B1 transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000017014.4|UniProtKB=A0A5F8GIC5 A0A5F8GIC5 PTHR11818:SF38 BETA/GAMMA CRYSTALLIN VERY LARGE A-KINASE ANCHOR PROTEIN structural molecule activity#GO:0005198 sensory organ development#GO:0007423;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;multicellular organism development#GO:0007275;animal organ development#GO:0048513;system process#GO:0003008;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;sensory perception#GO:0007600;nervous system process#GO:0050877;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;sensory perception of light stimulus#GO:0050953;visual perception#GO:0007601;visual system development#GO:0150063 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000029104.2|UniProtKB=K7E376 K7E376 GNG4 PTHR13809:SF21 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-4 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562;catalytic complex#GO:1902494;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;membrane protein complex#GO:0098796 heterotrimeric G-protein#PC00117 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (s)#P05977;Enkephalin release#P05913>G-Protein (i)#P05974;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Wnt signaling pathway#P00057>Ggamma#P01465;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;GABA-B receptor II signaling#P05731>Ggamma#P05754;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Dopamine receptor mediated signaling pathway#P05912>Ggamma#P05967;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 MONDO|Ensembl=ENSMODG00000013107.4|UniProtKB=F7BN00 F7BN00 MOCS1 PTHR22960:SF0 MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1 catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;biosynthetic process#GO:0009058 MONDO|Ensembl=ENSMODG00000018568.3|UniProtKB=F7FRQ9 F7FRQ9 TAF10 PTHR21242:SF0 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;nuclear DNA-directed RNA polymerase complex#GO:0055029;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;transferase complex#GO:1990234;peptidase complex#GO:1905368;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000019772.4|UniProtKB=F6W7Z2 F6W7Z2 GAPVD1 PTHR23101:SF25 RAB GDP/GTP EXCHANGE FACTOR GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;intracellular vesicle#GO:0097708;vesicle#GO:0031982 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000050164.1|UniProtKB=A0A5F8GF59 A0A5F8GF59 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000549.4|UniProtKB=F6XM07 F6XM07 PPARGC1A PTHR15528:SF10 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organismal-level homeostasis#GO:0048871;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000009129.4|UniProtKB=A0A5F8HI10 A0A5F8HI10 THUMPD2 PTHR14911:SF1 THUMP DOMAIN-CONTAINING U6 SNRNA (GUANINE-N(2))-METHYLTRANSFERASE THUMPD2 RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a tRNA#GO:0140101;tRNA (guanine) methyltransferase activity#GO:0016423;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000002759.3|UniProtKB=F6YH95 F6YH95 PTHR34994:SF1 PROTEIN FAM25A-RELATED PROTEIN FAM25A-RELATED MONDO|Ensembl=ENSMODG00000025443.3|UniProtKB=A0A5F8GQI9 A0A5F8GQI9 LOC100030951 PTHR14897:SF5 WD REPEAT AND COILED-COIL-CONTAINING PROTEIN WD REPEAT AND COILED-COIL-CONTAINING PROTEIN enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 MONDO|Ensembl=ENSMODG00000046685.1|UniProtKB=A0A5F8GW97 A0A5F8GW97 SLC25A38 PTHR46181:SF3 MITOCHONDRIAL GLYCINE TRANSPORTER MITOCHONDRIAL GLYCINE TRANSPORTER transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;amino acid transmembrane transporter activity#GO:0015171;glycine transmembrane transporter activity#GO:0015187 amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;glycine transport#GO:0015816;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;establishment of localization#GO:0051234;organic acid transport#GO:0015849;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;transport#GO:0006810;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000016152.4|UniProtKB=F7D6V2 F7D6V2 NUDCD3 PTHR12356:SF19 NUCLEAR MOVEMENT PROTEIN NUDC NUDC DOMAIN-CONTAINING PROTEIN 3 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000001465.4|UniProtKB=F7APP4 F7APP4 EPHA1 PTHR24416:SF28 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-A RECEPTOR 1 catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003558.4|UniProtKB=F7GBD3 F7GBD3 GOT1 PTHR11879:SF3 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE, CYTOPLASMIC cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;transaminase#PC00216;transferase#PC00220 Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854 MONDO|Ensembl=ENSMODG00000002283.4|UniProtKB=F7CVK9 F7CVK9 NT5DC3 PTHR12103:SF11 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 3 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 hydrolase#PC00121;nucleotide phosphatase#PC00173;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000050863.1|UniProtKB=A0A5F8GTX8 A0A5F8GTX8 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019368.4|UniProtKB=F6WTB2 F6WTB2 PDE8A PTHR11347:SF85 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8A cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;cellular response to growth factor stimulus#GO:0071363;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of response to stimulus#GO:0048584;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of MAPK cascade#GO:0043410;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533 hydrolase#PC00121;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000009707.5|UniProtKB=F6XTP4 F6XTP4 IQSEC2 PTHR10663:SF314 GUANYL-NUCLEOTIDE EXCHANGE FACTOR IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 2 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of endocytosis#GO:0030100;regulation of signaling#GO:0023051;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of biological quality#GO:0065008 cell junction#GO:0030054;synaptic membrane#GO:0097060;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic density membrane#GO:0098839;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000043365.1|UniProtKB=K7DYS2 K7DYS2 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED RETROVIRAL ENVELOPE PROTEIN GP41-LIKE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009989.4|UniProtKB=F7F2E6 F7F2E6 EHF PTHR11849:SF171 ETS ETS HOMOLOGOUS FACTOR DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 MONDO|Ensembl=ENSMODG00000048688.1|UniProtKB=A0A5F8H703 A0A5F8H703 PTHR23147:SF3 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 12 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear speck#GO:0016607;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000003517.3|UniProtKB=A0A5F8GGR3 A0A5F8GGR3 CHMP1A PTHR10476:SF17 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 1A localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;late endosome to vacuole transport#GO:0045324;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000049300.1|UniProtKB=A0A5F8GB99 A0A5F8GB99 LOC100012815 PTHR26453:SF58 OLFACTORY RECEPTOR OLFACTORY RECEPTOR FAMILY 13 SUBFAMILY P MEMBER 9 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006127.4|UniProtKB=F7EHN2 F7EHN2 SPON1 PTHR11311:SF16 SPONDIN SPONDIN-1 cell adhesion#GO:0007155;cellular process#GO:0009987 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000019108.4|UniProtKB=F7F998 F7F998 HNF1B PTHR11568:SF2 HEPATOCYTE NUCLEAR FACTOR 1 HEPATOCYTE NUCLEAR FACTOR 1-BETA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000048102.1|UniProtKB=A0A5F8H6K8 A0A5F8H6K8 LOC100031275 PTHR26454:SF77 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020163.4|UniProtKB=F6YRB9 F6YRB9 ARRDC3 PTHR11188:SF49 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 3 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000042070.1|UniProtKB=A0A5F8G4B3 A0A5F8G4B3 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000015781.4|UniProtKB=F6Z4D2 F6Z4D2 PTHR19229:SF98 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA3 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876;localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000018298.4|UniProtKB=F6PW38 F6PW38 MIX23 PTHR31905:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 58 PROTEIN MIX23 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000018769.5|UniProtKB=F7DXN5 F7DXN5 MTMR11 PTHR10807:SF51 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 11 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;dephosphorylation#GO:0016311;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000022961.2|UniProtKB=F6RH02 F6RH02 PTHR23138:SF94 RAN BINDING PROTEIN RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN establishment of localization in cell#GO:0051649;cellular process#GO:0009987;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;transport#GO:0006810;intracellular transport#GO:0046907 organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000043774.1|UniProtKB=A0A5F8GPY1 A0A5F8GPY1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016478.4|UniProtKB=F6ZDI9 F6ZDI9 A1CF PTHR21245:SF8 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN APOBEC1 COMPLEMENTATION FACTOR RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000017152.4|UniProtKB=F6QDR4 F6QDR4 PNPLA7 PTHR14226:SF23 NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 7 phosphatidylcholine lysophospholipase A1 activity#GO:0004622;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;esterase#PC00097 MONDO|Ensembl=ENSMODG00000043707.1|UniProtKB=A0A5F8GBF4 A0A5F8GBF4 PTHR16515:SF71 PR DOMAIN ZINC FINGER PROTEIN ZINC FINGER PROTEIN 22 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000041870.1|UniProtKB=A0A5F8HBE6 A0A5F8HBE6 PTHR10010:SF23 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;phosphate transmembrane transporter activity#GO:0005315;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324 phosphate ion transport#GO:0006817;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;cellular homeostasis#GO:0019725;inorganic anion transport#GO:0015698;intracellular chemical homeostasis#GO:0055082 brush border#GO:0005903;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;organelle#GO:0043226;apical part of cell#GO:0045177;cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000019089.4|UniProtKB=F6VLK1 F6VLK1 ACADM PTHR48083:SF41 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000015736.4|UniProtKB=F7B4M0 F7B4M0 C5orf63 PTHR33558:SF1 GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000002470.5|UniProtKB=F7BWB5 F7BWB5 NCL PTHR23236:SF128 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H NUCLEOLIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000016443.4|UniProtKB=F7B6R4 F7B6R4 ZNF263 PTHR23226:SF401 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 263 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011470.4|UniProtKB=F6VK12 F6VK12 ACSL4 PTHR43272:SF22 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 4 ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;cell differentiation#GO:0030154;small molecule metabolic process#GO:0044281;generation of neurons#GO:0048699;oxoacid metabolic process#GO:0043436;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;long-chain fatty acid metabolic process#GO:0001676;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron differentiation#GO:0030182;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 ligase#PC00142 MONDO|Ensembl=ENSMODG00000050944.1|UniProtKB=H9H9I1 H9H9I1 PTHR11387:SF12 CYTOCHROME C OXIDASE SUBUNIT 6B CYTOCHROME C OXIDASE SUBUNIT 6B2 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;oxidase#PC00175 MONDO|Ensembl=ENSMODG00000015724.4|UniProtKB=A0A5F8GKW7 A0A5F8GKW7 PRRC1 PTHR23276:SF2 PROTEIN PRRC1 PROTEIN PRRC1 binding#GO:0005488;protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515 homeostatic process#GO:0042592;epithelial structure maintenance#GO:0010669;tissue homeostasis#GO:0001894;multicellular organismal-level homeostasis#GO:0048871;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000046682.1|UniProtKB=A0A5F8HCP8 A0A5F8HCP8 CHURC1 PTHR31931:SF2 PROTEIN CHURCHILL PROTEIN CHURCHILL cell surface receptor signaling pathway#GO:0007166;response to fibroblast growth factor#GO:0071774;biological regulation#GO:0065007;fibroblast growth factor receptor signaling pathway#GO:0008543;signal transduction#GO:0007165;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719 MONDO|Ensembl=ENSMODG00000039432.1|UniProtKB=A0A5F8HB65 A0A5F8HB65 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000023879.2|UniProtKB=F7FYK3 F7FYK3 TRAPPC5 PTHR20902:SF0 41-2 PROTEIN ANTIGEN-RELATED TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 cytoplasm#GO:0005737;TRAPP complex#GO:0030008;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 MONDO|Ensembl=ENSMODG00000011130.3|UniProtKB=F7BAR9 F7BAR9 LOC100619070 PTHR24376:SF85 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 600-RELATED regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000000211.3|UniProtKB=F6TF12 F6TF12 PTHR10502:SF239 ANNEXIN ANNEXIN A7 ion binding#GO:0043167;phospholipid binding#GO:0005543;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000004504.3|UniProtKB=F6V9Y7 F6V9Y7 MMAB PTHR12213:SF0 CORRINOID ADENOSYLTRANSFERASE CORRINOID ADENOSYLTRANSFERASE MMAB catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000014635.4|UniProtKB=F7GBY4 F7GBY4 FA2H PTHR16047:SF7 RFWD3 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RFWD3 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000028930.2|UniProtKB=K7E2K2 K7E2K2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000021235.4|UniProtKB=A0A5F8H780 A0A5F8H780 GK5 PTHR10196:SF68 SUGAR KINASE GLYCEROL KINASE 5 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;alcohol metabolic process#GO:0006066;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;neutral lipid metabolic process#GO:0006638;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate metabolic process#GO:0005975;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281 mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase#PC00137;carbohydrate kinase#PC00065 MONDO|Ensembl=ENSMODG00000024540.3|UniProtKB=F7ANN1 F7ANN1 PTHR11481:SF64 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;immune response#GO:0006955;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;immune system process#GO:0002376;cell communication#GO:0007154 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000024074.2|UniProtKB=A0A5F8HJW8 A0A5F8HJW8 PTHR31661:SF2 SIMILAR TO CDNA SEQUENCE BC052040 CDAN1-INTERACTING NUCLEASE 1 myeloid cell differentiation#GO:0030099;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;cell development#GO:0048468;homeostatic process#GO:0042592;hemopoiesis#GO:0030097;cellular process#GO:0009987;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;multicellular organismal-level homeostasis#GO:0048871;immune system process#GO:0002376;developmental process#GO:0032502;homeostasis of number of cells#GO:0048872 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000006463.3|UniProtKB=A0A5F8H203 A0A5F8H203 CCDC159 PTHR34533:SF1 TRANSMEMBRANE PROTEIN CCDC163 COILED-COIL DOMAIN-CONTAINING PROTEIN 159 MONDO|Ensembl=ENSMODG00000049965.1|UniProtKB=A0A5F8GZF7 A0A5F8GZF7 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000018243.4|UniProtKB=A0A5F8GLD6 A0A5F8GLD6 STXBP5L PTHR10241:SF19 LETHAL 2 GIANT LARVAE PROTEIN SYNTAXIN-BINDING PROTEIN 5-LIKE myosin binding#GO:0017022;enzyme activator activity#GO:0008047;SNARE binding#GO:0000149;cytoskeletal protein binding#GO:0008092;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;syntaxin binding#GO:0019905;molecular function activator activity#GO:0140677 Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization within membrane#GO:0051668;exocytosis#GO:0006887;vesicle-mediated transport to the plasma membrane#GO:0098876;post-Golgi vesicle-mediated transport#GO:0006892;secretion by cell#GO:0032940;establishment of localization#GO:0051234;secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;Golgi to plasma membrane transport#GO:0006893 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000025613.2|UniProtKB=F6QBB7 F6QBB7 ALKAL1 PTHR28676:SF1 ALK AND LTK LIGAND 2-RELATED ALK AND LTK LIGAND 1 protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;kinase activator activity#GO:0019209;protein kinase activator activity#GO:0030295;receptor tyrosine kinase binding#GO:0030971;molecular function regulator activity#GO:0098772;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207 regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410 MONDO|Ensembl=ENSMODG00000004841.3|UniProtKB=F6U5G0 F6U5G0 PTHR45677:SF6 GLUTAMATE DECARBOXYLASE-RELATED GLUTAMATE DECARBOXYLASE 1 lyase activity#GO:0016829;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830 small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 presynapse#GO:0098793;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;presynaptic active zone#GO:0048786;synapse#GO:0045202;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000001542.3|UniProtKB=F7EMH4 F7EMH4 CYTL1 PTHR15974:SF0 CYTOKINE-LIKE PROTEIN 1 CYTOKINE-LIKE PROTEIN 1 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cytokine#PC00083 MONDO|Ensembl=ENSMODG00000019281.4|UniProtKB=A0A5F8GAP0 A0A5F8GAP0 LOC100030497 PTHR11388:SF160 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000043801.1|UniProtKB=A0A5F8GDI3 A0A5F8GDI3 TOX3 PTHR45781:SF3 AGAP000281-PA TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 3 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000019823.4|UniProtKB=F6SB23 F6SB23 SLC1A2 PTHR11958:SF93 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 2 sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;solute:monoatomic cation symporter activity#GO:0015294;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;acidic amino acid transmembrane transporter activity#GO:0015172;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857 nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;aspartate transmembrane transport#GO:0015810;cellular process#GO:0009987;dicarboxylic acid transport#GO:0006835;L-glutamate transmembrane transport#GO:0015813;amino acid transport#GO:0006865;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;C4-dicarboxylate transport#GO:0015740;establishment of localization#GO:0051234;import into cell#GO:0098657;L-alpha-amino acid transmembrane transport#GO:1902475;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;L-glutamate import#GO:0051938;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036;Ionotropic glutamate receptor pathway#P00037>EAAT#P01011 MONDO|Ensembl=ENSMODG00000013679.4|UniProtKB=F6QQ94 F6QQ94 ACOT8 PTHR11066:SF34 ACYL-COA THIOESTERASE ACYL-COENZYME A THIOESTERASE 8 hydrolase activity#GO:0016787;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;acyl-CoA hydrolase activity#GO:0016289;fatty acyl-CoA hydrolase activity#GO:0047617;deacylase activity#GO:0160215;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 microbody#GO:0042579;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782 metabolite interconversion enzyme#PC00262;esterase#PC00097;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000024676.3|UniProtKB=F7GCY0 F7GCY0 PTHR24115:SF344 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF28P polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774 transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;vesicle cytoskeletal trafficking#GO:0099518;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656 intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000009053.5|UniProtKB=F7AF98 F7AF98 NPAS1 PTHR23043:SF25 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA NEURONAL PAS DOMAIN-CONTAINING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000027711.2|UniProtKB=A0A5F8GJP2 A0A5F8GJP2 PTHR26450:SF52 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR FAMILY 56 SUBFAMILY A MEMBER 41, PSEUDOGENE 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000047632.1|UniProtKB=A0A5F8GCN2 A0A5F8GCN2 LOC100030291 PTHR26451:SF132 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 6K6 binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000044868.1|UniProtKB=A0A5F8GAG1 A0A5F8GAG1 EMG1 PTHR12636:SF5 NEP1/MRA1 RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1 RNA binding#GO:0003723;catalytic activity, acting on a rRNA#GO:0140102;nucleic acid binding#GO:0003676;binding#GO:0005488;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA binding#GO:0019843;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640 rRNA methylation#GO:0031167;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;rRNA base methylation#GO:0070475;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA modification#GO:0000154 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229 transferase#PC00220;methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000000614.4|UniProtKB=F6TAZ7 F6TAZ7 PTHR19134:SF331 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE V phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;axon guidance#GO:0007411;axon development#GO:0061564;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036 protein phosphatase#PC00195;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000048380.1|UniProtKB=A0A5F8G376 A0A5F8G376 OSM PTHR14261:SF0 ONCOSTATIN M ONCOSTATIN-M signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;positive regulation of inflammatory response#GO:0050729;positive regulation of defense response#GO:0031349;regulation of inflammatory response#GO:0050727;regulation of response to stimulus#GO:0048583;regulation of defense response#GO:0031347;positive regulation of response to external stimulus#GO:0032103 interleukin superfamily#PC00128;cytokine#PC00083;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000041386.1|UniProtKB=A0A5F8GL52 A0A5F8GL52 PTHR10177:SF444 CYCLINS CYCLIN-A2 kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin A#P04666 MONDO|Ensembl=ENSMODG00000024567.3|UniProtKB=F7BU50 F7BU50 TRIQK PTHR20583:SF1 TRIPLE QXXK/R MOTIF-CONTAINING PROTEIN TRIPLE QXXK_R MOTIF-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000003825.4|UniProtKB=F7GJE9 F7GJE9 AQP3 PTHR43829:SF7 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-3 channel activity#GO:0015267;carbohydrate transmembrane transporter activity#GO:0015144;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 fluid transport#GO:0042044;organic hydroxy compound transport#GO:0015850;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;water transport#GO:0006833;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643;carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987 membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000002278.4|UniProtKB=A0A5F8GKZ5 A0A5F8GKZ5 LOC100015414 PTHR12084:SF0 NUCLEAR PORE GLYCOPROTEIN P62-RELATED NUCLEAR PORE GLYCOPROTEIN P62 structural molecule activity#GO:0005198;lipid binding#GO:0008289;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488;phospholipid binding#GO:0005543 protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;nucleobase-containing compound transport#GO:0015931;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036 nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 transporter#PC00227 MONDO|Ensembl=ENSMODG00000003256.3|UniProtKB=F6T0X0 F6T0X0 CDH1 PTHR24027:SF319 CADHERIN-23 CADHERIN-1 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;nervous system development#GO:0007399;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;cell migration#GO:0016477;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell motility#GO:0048870;cell junction organization#GO:0034330;synapse assembly#GO:0007416;cell adhesion#GO:0007155;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856 plasma membrane protein complex#GO:0098797;membrane raft#GO:0045121;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;plasma membrane raft#GO:0044853;cell periphery#GO:0071944;caveola#GO:0005901;membrane#GO:0016020;cell-cell junction#GO:0005911;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;membrane microdomain#GO:0098857;apical junction complex#GO:0043296;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Alzheimer disease-presenilin pathway#P00004>E-cadherin C-terminal fragment#P00117;CCKR signaling map#P06959>E-cadherin#G06981;Wnt signaling pathway#P00057>Cadherin#P01440;Alzheimer disease-presenilin pathway#P00004>E-cadherin intracellular fragment#P00168;Alzheimer disease-presenilin pathway#P00004>E-cadherin#P00118;Alzheimer disease-presenilin pathway#P00004>E-cadherin N-terminal fragment#P00165;CCKR signaling map#P06959>E-cadherin#P07171;Alzheimer disease-presenilin pathway#P00004>E-cadherin transmembrane fragment#P00139;CCKR signaling map#P06959>E-cadherin#G07274 MONDO|Ensembl=ENSMODG00000024700.2|UniProtKB=F7B231 F7B231 PTHR14499:SF7 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD11 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013730.3|UniProtKB=F6XQK5 F6XQK5 PTHR11431:SF47 FERRITIN FERRITIN LIGHT CHAIN iron ion binding#GO:0005506;ferrous iron binding#GO:0008198;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 storage protein#PC00210 MONDO|Ensembl=ENSMODG00000025252.3|UniProtKB=F7F5V1 F7F5V1 PTHR26454:SF27 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020907.5|UniProtKB=H9H9F4 H9H9F4 EPN3 PTHR12276:SF16 EPSIN/ENT-RELATED EPSIN-3 protein binding#GO:0005515;lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543;clathrin binding#GO:0030276 transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle#GO:0030136;plasma membrane#GO:0005886;vesicle coat#GO:0030120;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular organelle#GO:0043229;endosome#GO:0005768;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000013596.1|UniProtKB=F6VVV1 F6VVV1 KRT40 PTHR23239:SF90 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 40 structural molecule activity#GO:0005198 intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;supramolecular fiber organization#GO:0097435;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;developmental process#GO:0032502;morphogenesis of an epithelium#GO:0002009;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000041047.1|UniProtKB=A0A5F8GR78 A0A5F8GR78 LOC100022789 PTHR26452:SF930 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001161.4|UniProtKB=F7CJR8 F7CJR8 LEPR PTHR23037:SF44 CYTOKINE RECEPTOR LEPTIN RECEPTOR immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of cellular process#GO:0050794 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015627.3|UniProtKB=F7FEU7 F7FEU7 IL27 PTHR20879:SF1 INTERLEUKIN-27 SUBUNIT ALPHA INTERLEUKIN-27 SUBUNIT ALPHA binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;protein binding#GO:0005515 regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;regulation of T cell activation#GO:0050863;regulation of cell development#GO:0060284;regulation of mononuclear cell proliferation#GO:0032944;regulation of leukocyte proliferation#GO:0070663;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;regulation of lymphocyte activation#GO:0051249;regulation of developmental process#GO:0050793;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of T cell proliferation#GO:0042129;regulation of cell activation#GO:0050865;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694;regulation of immune effector process#GO:0002697;regulation of cell population proliferation#GO:0042127;regulation of hemopoiesis#GO:1903706;regulation of immune response#GO:0050776 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interleukin superfamily#PC00128;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000011910.4|UniProtKB=A0A5F8GPP5 A0A5F8GPP5 NEK11 PTHR43671:SF111 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK11 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular response to stress#GO:0033554;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of cell cycle#GO:0045786;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;DNA integrity checkpoint signaling#GO:0031570;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000000094.4|UniProtKB=F6YCB1 F6YCB1 APPL1 PTHR46415:SF3 ADAPTOR PROTEIN, PHOSPHOTYROSINE INTERACTION, PH DOMAIN AND LEUCINE ZIPPER-CONTAINING 2 DCC-INTERACTING PROTEIN 13-ALPHA protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000002682.4|UniProtKB=F7CYN9 F7CYN9 NCOA4 PTHR17085:SF3 NUCLEAR RECEPTOR COACTIVATOR 4 NUCLEAR RECEPTOR COACTIVATOR 4 response to stimulus#GO:0050896;response to chemical#GO:0042221;response to hormone#GO:0009725;response to endogenous stimulus#GO:0009719 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000046522.1|UniProtKB=A0A5F8G9K0 A0A5F8G9K0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024966.2|UniProtKB=F6QMN9 F6QMN9 PTHR26451:SF928 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G PROTEIN-COUPLED RECEPTOR 148-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000011966.3|UniProtKB=F7CUW8 F7CUW8 TWNK PTHR12873:SF7 T7-LIKE MITOCHONDRIAL DNA HELICASE TWINKLE MTDNA HELICASE isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular process#GO:0009987;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;mitochondrial DNA metabolic process#GO:0032042;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 DNA helicase#PC00011 MONDO|Ensembl=ENSMODG00000001044.3|UniProtKB=F6ZEW7 F6ZEW7 PTHR11620:SF104 60S RIBOSOMAL PROTEIN L23A LARGE RIBOSOMAL SUBUNIT PROTEIN UL23 N-TERMINAL DOMAIN-CONTAINING PROTEIN structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000028784.2|UniProtKB=K7E065 K7E065 C1orf53 PTHR21037:SF2 39S RIBOSOMAL PROTEIN L14, MITOCHONDRIAL SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 53 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000029458.2|UniProtKB=F7FWL1 F7FWL1 PTHR47309:SF1 T-CELL SURFACE GLYCOPROTEIN CD5 T-CELL SURFACE GLYCOPROTEIN CD5 immune system process#GO:0002376;positive regulation of lymphocyte activation#GO:0051251;regulation of leukocyte activation#GO:0002694;regulation of biological process#GO:0050789;positive regulation of cell adhesion#GO:0045785;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of leukocyte activation#GO:0002696;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of T cell activation#GO:0050870;regulation of cell adhesion#GO:0030155;regulation of T cell activation#GO:0050863;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;regulation of multicellular organismal process#GO:0051239 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000003824.4|UniProtKB=F7GJE7 F7GJE7 MARCHF2 PTHR46065:SF4 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE MARCHF2 aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000040227.1|UniProtKB=A0A5F8HHB0 A0A5F8HHB0 TAF12 PTHR12264:SF21 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 MONDO|Ensembl=ENSMODG00000016512.3|UniProtKB=F7EQD6 F7EQD6 PCK1 PTHR11561:SF18 PHOSPHOENOLPYRUVATE CARBOXYKINASE PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC [GTP] carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914 cellular homeostasis#GO:0019725;cellular response to insulin stimulus#GO:0032869;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;response to peptide hormone#GO:0043434;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;response to glucose#GO:0009749;epithelial cell differentiation#GO:0030855;anatomical structure development#GO:0048856;response to steroid hormone#GO:0048545;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;glucose homeostasis#GO:0042593;multicellular organism development#GO:0007275;cellular response to steroid hormone stimulus#GO:0071383;alcohol metabolic process#GO:0006066;carbohydrate biosynthetic process#GO:0016051;cellular response to lipid#GO:0071396;alcohol biosynthetic process#GO:0046165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to carbohydrate#GO:0009743;response to monosaccharide#GO:0034284;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;response to stimulus#GO:0050896;liver development#GO:0001889;cellular response to hormone stimulus#GO:0032870;intracellular chemical homeostasis#GO:0055082;cellular developmental process#GO:0048869;developmental process#GO:0032502;small molecule biosynthetic process#GO:0044283;cellular response to nitrogen compound#GO:1901699;tissue development#GO:0009888;response to nutrient levels#GO:0031667;system development#GO:0048731;response to nitrogen compound#GO:1901698;homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975;cellular response to peptide hormone stimulus#GO:0071375;hexose biosynthetic process#GO:0019319;response to starvation#GO:0042594;animal organ development#GO:0048513;glucose metabolic process#GO:0006006;chemical homeostasis#GO:0048878;cellular response to glucose stimulus#GO:0071333;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;response to chemical#GO:0042221;response to lipid#GO:0033993;gluconeogenesis#GO:0006094;response to stress#GO:0006950;response to hormone#GO:0009725;intracellular glucose homeostasis#GO:0001678;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;cell differentiation#GO:0030154;small molecule metabolic process#GO:0044281;cellular response to endogenous stimulus#GO:0071495;carbohydrate homeostasis#GO:0033500;response to hexose#GO:0009746;response to endogenous stimulus#GO:0009719;carboxylic acid metabolic process#GO:0019752 mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 Pyruvate metabolism#P02772>Phosphoenolpyruvate Carboxykinase#P03135 MONDO|Ensembl=ENSMODG00000038092.1|UniProtKB=A0A5F8GGI2 A0A5F8GGI2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000028067.2|UniProtKB=K7E5U1 K7E5U1 EDN2 PTHR13874:SF9 ENDOTHELIN ENDOTHELIN-2 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 muscle contraction#GO:0006936;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;regulation of anatomical structure size#GO:0090066;regulation of system process#GO:0044057;intracellular chemical homeostasis#GO:0055082;system process#GO:0003008;intracellular calcium ion homeostasis#GO:0006874;regulation of smooth muscle contraction#GO:0006940;cellular homeostasis#GO:0019725;positive regulation of biological process#GO:0048518;regulation of blood pressure#GO:0008217;monoatomic ion homeostasis#GO:0050801;regulation of systemic arterial blood pressure#GO:0003073;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;inorganic ion homeostasis#GO:0098771;regulation of muscle contraction#GO:0006937;calcium ion homeostasis#GO:0055074;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;muscle system process#GO:0003012;positive regulation of multicellular organismal process#GO:0051240;intracellular monoatomic ion homeostasis#GO:0006873;regulation of muscle system process#GO:0090257;homeostatic process#GO:0042592 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 Endothelin signaling pathway#P00019>ET1-4#P00588;Endothelin signaling pathway#P00019>Pro ET1-4#P00571;Endothelin signaling pathway#P00019>Big ET1-4#P00574;Endothelin signaling pathway#P00019>Pre-pro ET1-4#P00576 MONDO|Ensembl=ENSMODG00000016446.2|UniProtKB=A0A5F8GH88 A0A5F8GH88 PTHR10732:SF14 40S RIBOSOMAL PROTEIN S17 SMALL RIBOSOMAL SUBUNIT PROTEIN ES17 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000008331.4|UniProtKB=F7F2M9 F7F2M9 LOC100018894 PTHR24300:SF444 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 binding#GO:0005488;tetrapyrrole binding#GO:0046906;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;response to chemical#GO:0042221;icosanoid metabolic process#GO:0006690;cellular response to xenobiotic stimulus#GO:0071466;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;olefinic compound metabolic process#GO:0120254;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;arachidonate metabolic process#GO:0019369;cellular response to stimulus#GO:0051716;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000041679.1|UniProtKB=A0A5F8H8F4 A0A5F8H8F4 PTHR12307:SF15 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3C protein phosphatase binding#GO:0019903;protein binding#GO:0005515;carbohydrate binding#GO:0030246;enzyme binding#GO:0019899;phosphatase binding#GO:0019902;polysaccharide binding#GO:0030247;binding#GO:0005488 regulation of carbohydrate metabolic process#GO:0006109;regulation of glycogen biosynthetic process#GO:0005979;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of polysaccharide metabolic process#GO:0032881;regulation of carbohydrate biosynthetic process#GO:0043255;biological regulation#GO:0065007 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000007014.4|UniProtKB=F6XCG4 F6XCG4 FH PTHR11444:SF1 ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE FUMARATE HYDRATASE, MITOCHONDRIAL hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 lyase#PC00144 TCA cycle#P00051>Fumarase#P01271 MONDO|Ensembl=ENSMODG00000023594.3|UniProtKB=F7DGL2 F7DGL2 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009003.4|UniProtKB=F7BQ48 F7BQ48 LOC100028995 PTHR22762:SF104 ALPHA-GLUCOSIDASE P-TYPE DOMAIN-CONTAINING PROTEIN glucosidase activity#GO:0015926;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;alpha-glucosidase activity#GO:0090599 glucosidase#PC00108 MONDO|Ensembl=ENSMODG00000007441.4|UniProtKB=F7DW81 F7DW81 SULF1 PTHR43108:SF1 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER EXTRACELLULAR SULFATASE SULF-1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;carbohydrate derivative catabolic process#GO:1901136;protein metabolic process#GO:0019538;positive regulation of biosynthetic process#GO:0009891;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;positive regulation of cellular process#GO:0048522;carbohydrate derivative metabolic process#GO:1901135;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;negative regulation of biological process#GO:0048519;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;positive regulation of signaling#GO:0023056;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of Wnt signaling pathway#GO:0030177;negative regulation of signal transduction#GO:0009968;regulation of multicellular organismal process#GO:0051239;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;proteoglycan metabolic process#GO:0006029 extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000023601.3|UniProtKB=F7FB44 F7FB44 LOC100020297 PTHR24377:SF1028 IP01015P-RELATED ZINC FINGER PROTEIN 84 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000007623.5|UniProtKB=F7E8S3 F7E8S3 KTN1 PTHR18864:SF1 KINECTIN KINECTIN MONDO|Ensembl=ENSMODG00000002062.4|UniProtKB=F6V009 F6V009 SORT1 PTHR12106:SF23 SORTILIN RELATED SORTILIN vesicle-mediated transport#GO:0016192;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;vesicle organization#GO:0016050;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;endocytosis#GO:0006897;cytosolic transport#GO:0016482;cellular component organization#GO:0016043;Golgi to endosome transport#GO:0006895;localization#GO:0051179;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000029043.2|UniProtKB=K7DZR3 K7DZR3 PTHR12015:SF210 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 9 G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379 granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;cellular response to cytokine stimulus#GO:0071345;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;response to peptide#GO:1901652;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;granulocyte migration#GO:0097530;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;neutrophil migration#GO:1990266;response to chemical#GO:0042221;taxis#GO:0042330;response to cytokine#GO:0034097;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to lipopolysaccharide#GO:0032496;neutrophil chemotaxis#GO:0030593;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;cell motility#GO:0048870;locomotion#GO:0040011;cellular response to chemokine#GO:1990869;response to external biotic stimulus#GO:0043207;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;cell chemotaxis#GO:0060326;cytokine-mediated signaling pathway#GO:0019221;response to bacterium#GO:0009617;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cell migration#GO:0016477;response to other organism#GO:0051707;biological regulation#GO:0065007;cellular response to molecule of bacterial origin#GO:0071219;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;leukocyte migration#GO:0050900 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 MONDO|Ensembl=ENSMODG00000007971.4|UniProtKB=F7DQP1 F7DQP1 PTHR45935:SF15 PROTEIN ZBED8-RELATED SCAN DOMAIN-CONTAINING PROTEIN 3 MONDO|Ensembl=ENSMODG00000008705.4|UniProtKB=F6PWJ8 F6PWJ8 CYP2W1 PTHR24300:SF291 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2W1 binding#GO:0005488;tetrapyrrole binding#GO:0046906;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000040790.1|UniProtKB=F7EWZ9 F7EWZ9 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016565.2|UniProtKB=H9H6Z5 H9H6Z5 CSDC2 PTHR12962:SF4 CALCIUM-REGULATED HEAT STABLE PROTEIN CRHSP-24-RELATED COLD SHOCK DOMAIN-CONTAINING PROTEIN C2 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA stability#GO:0043488;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;regulation of biological quality#GO:0065008;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000025216.3|UniProtKB=A0A5F8H9C6 A0A5F8H9C6 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000012794.3|UniProtKB=F7EFU5 F7EFU5 PTHR12713:SF5 VACUOLAR ATP SYNTHASE SUBUNIT G V-TYPE PROTON ATPASE SUBUNIT G 3 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular localization#GO:0051641;transmembrane transport#GO:0055085;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular homeostasis#GO:0019725;vesicle organization#GO:0016050;synaptic vesicle maturation#GO:0016188;proton transmembrane transport#GO:1902600;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;developmental process#GO:0032502;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;developmental maturation#GO:0021700;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular membrane-bounded organelle#GO:0043231;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cation-transporting ATPase complex#GO:0090533;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;vacuolar membrane#GO:0005774;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506;ATPase dependent transmembrane transport complex#GO:0098533;ATPase complex#GO:1904949;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;transporter complex#GO:1990351;cell junction#GO:0030054;proton-transporting two-sector ATPase complex#GO:0016469;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;presynapse#GO:0098793;secretory vesicle#GO:0099503 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000019212.4|UniProtKB=H9H7A7 H9H7A7 MTMR8 PTHR10807:SF36 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR8 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;dephosphorylation#GO:0016311;lipid modification#GO:0030258;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane#GO:0016020;organelle envelope#GO:0031967;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000013355.4|UniProtKB=F7GA53 F7GA53 UPK2 PTHR17573:SF0 UROPLAKIN II UROPLAKIN-2 cellular process#GO:0009987;cell differentiation#GO:0030154;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000004684.4|UniProtKB=F6U6G2 F6U6G2 SNX25 PTHR22775:SF48 SORTING NEXIN SORTING NEXIN-25 anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000002628.3|UniProtKB=A0A5F8GVH8 A0A5F8GVH8 ARMH1 PTHR34258:SF1 ARMADILLO-LIKE HELICAL DOMAIN CONTAINING PROTEIN 1 ARMADILLO-LIKE HELICAL DOMAIN CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000007458.4|UniProtKB=F7DAY0 F7DAY0 PTHR24020:SF13 COLLAGEN ALPHA COLLAGEN ALPHA-3(VI) CHAIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863 MONDO|Ensembl=ENSMODG00000019428.4|UniProtKB=F7G4S3 F7G4S3 ZFAND6 PTHR10634:SF25 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE ZINC FINGER PROTEIN 6 protein binding#GO:0005515;modification-dependent protein binding#GO:0140030;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593 establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;establishment of localization#GO:0051234;protein targeting#GO:0006605;establishment of protein localization#GO:0045184 MONDO|Ensembl=ENSMODG00000046524.1|UniProtKB=A0A5F8GV43 A0A5F8GV43 HOXD3 PTHR45664:SF5 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-D3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;skeletal system morphogenesis#GO:0048705;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;anterior/posterior pattern specification#GO:0009952;embryo development#GO:0009790;skeletal system development#GO:0001501;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000028778.2|UniProtKB=K7E1Q0 K7E1Q0 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000036946.1|UniProtKB=A0A5F8G5J9 A0A5F8G5J9 CAPZA1 PTHR10653:SF5 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-1 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament organization#GO:0110053;regulation of protein depolymerization#GO:1901879;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of actin filament depolymerization#GO:0030834;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of cellular component organization#GO:0051128;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of actin filament length#GO:0030832 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000002051.3|UniProtKB=A0A5F8GG14 A0A5F8GG14 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011280.4|UniProtKB=F6WZP6 F6WZP6 FBXL15 PTHR13318:SF179 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 15 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000011902.4|UniProtKB=F7EGX5 F7EGX5 ZSWIM4 PTHR22619:SF4 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 4 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul2-RING ubiquitin ligase complex#GO:0031462 MONDO|Ensembl=ENSMODG00000004917.4|UniProtKB=F7BH27 F7BH27 RSF1 PTHR14296:SF16 REMODELING AND SPACING FACTOR 1 REMODELING AND SPACING FACTOR 1 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;heterochromatin organization#GO:0070828;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular component assembly#GO:0022607;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ISWI-type complex#GO:0031010;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000012161.3|UniProtKB=F7CYK5 F7CYK5 EIF4EBP2 PTHR12669:SF4 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 2 translation initiation factor binding#GO:0031369;protein binding#GO:0005515;translation regulator activity#GO:0045182;binding#GO:0005488 negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of synaptic plasticity#GO:0048167;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of signaling#GO:0023051;regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148;regulation of biological quality#GO:0065008 translation initiation factor#PC00224;translation factor#PC00223 MONDO|Ensembl=ENSMODG00000012565.4|UniProtKB=F6PLC3 F6PLC3 SPACA9 PTHR32455:SF1 SPERM ACROSOME-ASSOCIATED PROTEIN 9 SPERM ACROSOME-ASSOCIATED PROTEIN 9 intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729;acrosomal vesicle#GO:0001669;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;secretory vesicle#GO:0099503;ciliary base#GO:0097546;cytoplasm#GO:0005737;endomembrane system#GO:0012505;sperm flagellum#GO:0036126 MONDO|Ensembl=ENSMODG00000011032.4|UniProtKB=F7F4C7 F7F4C7 CA12 PTHR18952:SF19 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 12 catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 monoatomic ion homeostasis#GO:0050801;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592 apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000011337.4|UniProtKB=F6W377 F6W377 RRAGB PTHR11259:SF1 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of TOR signaling#GO:0032008;negative regulation of catabolic process#GO:0009895;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;positive regulation of TORC1 signaling#GO:1904263;response to nutrient levels#GO:0031667;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular response to nutrient levels#GO:0031669;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;negative regulation of autophagy#GO:0010507 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;lysosome#GO:0005764;nucleus#GO:0005634;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000022931.1|UniProtKB=F7APE1 F7APE1 LOC100017477 PTHR26450:SF392 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008990.4|UniProtKB=F7BFB3 F7BFB3 MAN2C1 PTHR46017:SF1 ALPHA-MANNOSIDASE 2C1 ALPHA-MANNOSIDASE 2C1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311 MONDO|Ensembl=ENSMODG00000001215.4|UniProtKB=F7G7S0 F7G7S0 PLRG1 PTHR19923:SF0 WD40 REPEAT PROTEINPRL1/PRL2-RELATED PLEIOTROPIC REGULATOR 1 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 MONDO|Ensembl=ENSMODG00000018380.5|UniProtKB=F6QV52 F6QV52 OSBPL11 PTHR10972:SF46 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 11 binding#GO:0005488;sterol binding#GO:0032934;lipid binding#GO:0008289;steroid binding#GO:0005496 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;membrane#GO:0016020 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000017508.4|UniProtKB=A0A5F8GMD5 A0A5F8GMD5 LOC100619950 PTHR11430:SF142 LIPOCALIN LIPOCALIN_CYTOSOLIC FATTY-ACID BINDING DOMAIN-CONTAINING PROTEIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000020886.2|UniProtKB=H9H7P8 H9H7P8 TAS1R2 PTHR24061:SF517 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 2 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001877.4|UniProtKB=F6S687 F6S687 ZPLD1 PTHR14002:SF24 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002356.4|UniProtKB=F7GDM7 F7GDM7 CCT5 PTHR11353:SF94 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT EPSILON gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 protein folding chaperone complex#GO:0101031;chaperonin-containing T-complex#GO:0005832;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 chaperonin#PC00073 MONDO|Ensembl=ENSMODG00000027808.2|UniProtKB=K7E2E2 K7E2E2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000011692.3|UniProtKB=F7GDZ5 F7GDZ5 YIPF6 PTHR21236:SF1 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF6 Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000044553.1|UniProtKB=A0A5F8HDV4 A0A5F8HDV4 PTHR10489:SF671 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 3 G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;locomotion#GO:0040011;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cell communication#GO:0007154;chemotaxis#GO:0006935;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000041574.1|UniProtKB=A0A5F8GNP3 A0A5F8GNP3 SCAMP5 PTHR10687:SF5 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 5 export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;exocytosis#GO:0006887;secretion by cell#GO:0032940;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810 membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network membrane#GO:0032588;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;recycling endosome membrane#GO:0055038;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000004777.5|UniProtKB=F6WK76 F6WK76 BCAR3 PTHR14247:SF10 BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;response to peptide hormone#GO:0043434;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;epidermal growth factor receptor signaling pathway#GO:0007173;cellular response to nitrogen compound#GO:1901699;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;cellular response to insulin stimulus#GO:0032869;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of signaling#GO:0023056;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408 MONDO|Ensembl=ENSMODG00000010650.4|UniProtKB=F7D467 F7D467 PRKCD PTHR24356:SF365 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C DELTA TYPE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs(3)#P06850;Gonadotropin-releasing hormone receptor pathway#P06664>nPKCs#P06852;Apoptosis signaling pathway#P00006>PKCs#P00318;Alpha adrenergic receptor signaling pathway#P00002>PKC#P00075;B cell activation#P00010>PKC#P00373;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Endothelin signaling pathway#P00019>PKC#P00568;CCKR signaling map#P06959>PKCdelta#P07134;EGF receptor signaling pathway#P00018>PKC#P00565;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219 MONDO|Ensembl=ENSMODG00000007391.2|UniProtKB=F6YZ43 F6YZ43 LOC100029269 PTHR24242:SF183 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11G2 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000007099.4|UniProtKB=F6Q8M0 F6Q8M0 INTS8 PTHR13350:SF1 INTEGRATOR COMPLEX SUBUNIT 8 INTEGRATOR COMPLEX SUBUNIT 8 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123 integrator complex#GO:0032039;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000002455.4|UniProtKB=F7DEH2 F7DEH2 CAMK1G PTHR24347:SF116 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1G catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;calmodulin binding#GO:0005516;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;calcium/calmodulin-dependent protein kinase activity#GO:0004683 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000021485.5|UniProtKB=F7GK85 F7GK85 GREB1L PTHR15720:SF12 GREB1-RELATED GREB1-LIKE PROTEIN anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;kidney development#GO:0001822;renal system development#GO:0072001;anatomical structure morphogenesis#GO:0009653 MONDO|Ensembl=ENSMODG00000000157.4|UniProtKB=F6XSI5 F6XSI5 ZNF18 PTHR23226:SF190 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 18 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015249.4|UniProtKB=A0A5F8G9B8 A0A5F8G9B8 DNAJB2 PTHR43948:SF22 DNAJ HOMOLOG SUBFAMILY B 4930503B20RIK PROTEIN binding#GO:0005488;protein-folding chaperone binding#GO:0051087;protein binding#GO:0005515 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000005565.4|UniProtKB=F7F3M1 F7F3M1 PTHR23421:SF199 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 hydrolase#PC00121;galactosidase#PC00104 MONDO|Ensembl=ENSMODG00000013991.4|UniProtKB=F6QKC9 F6QKC9 ATP11C PTHR24092:SF38 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IG lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;intramembrane lipid carrier activity#GO:0140303 transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule localization#GO:0033036;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;phospholipid transport#GO:0015914;membrane organization#GO:0061024;lipid transport#GO:0006869;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748 cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;recycling endosome#GO:0055037;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000025452.2|UniProtKB=A0A5F8GAU5 A0A5F8GAU5 PTHR45616:SF10 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 79 structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;intermediate filament organization#GO:0045109;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;animal organ development#GO:0048513;epidermis development#GO:0008544;developmental process#GO:0032502;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;skin development#GO:0043588;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000000280.4|UniProtKB=H9H5V8 H9H5V8 PCBP2 PTHR10288:SF97 KH DOMAIN CONTAINING RNA BINDING PROTEIN POLY(RC)-BINDING PROTEIN 2 RNA binding#GO:0003723;DNA binding#GO:0003677;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697 positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000014992.4|UniProtKB=F7CG40 F7CG40 SIN3B PTHR12346:SF1 SIN3B-RELATED PAIRED AMPHIPATHIC HELIX PROTEIN SIN3B transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>Sin3A#P00771 MONDO|Ensembl=ENSMODG00000001489.3|UniProtKB=F7F4S7 F7F4S7 PDCL3 PTHR45809:SF4 VIRAL IAP-ASSOCIATED FACTOR HOMOLOG PHOSDUCIN-LIKE PROTEIN 3 protein binding#GO:0005515;growth factor receptor binding#GO:0070851;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 animal gross anatomical part developmental process#GO:0160108;angiogenesis#GO:0001525;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514;protein folding#GO:0006457;circulatory system development#GO:0072359;metabolic process#GO:0008152;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;protein maturation#GO:0051604;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;system development#GO:0048731;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;positive regulation of biosynthetic process#GO:0009891;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;tube development#GO:0035295;biological regulation#GO:0065007;biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010654.3|UniProtKB=F7D445 F7D445 LETM2 PTHR14009:SF7 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN LETM1 DOMAIN-CONTAINING PROTEIN LETM2, MITOCHONDRIAL transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;cellular component organization#GO:0016043;calcium ion transport#GO:0006816;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;mitochondrion organization#GO:0007005;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;organelle organization#GO:0006996;mitochondrial calcium ion transmembrane transport#GO:0006851 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000042223.1|UniProtKB=F6WP01 F6WP01 LOC130458013 PTHR21297:SF0 DNA-DIRECTED RNA POLYMERASE II DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 translation initiation factor binding#GO:0031369;protein binding#GO:0005515;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 MONDO|Ensembl=ENSMODG00000007376.4|UniProtKB=F6ZNG5 F6ZNG5 NCOA2 PTHR10684:SF2 NUCLEAR RECEPTOR COACTIVATOR NUCLEAR RECEPTOR COACTIVATOR 2 DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription regulator activity#GO:0140110;binding#GO:0005488;transcription coactivator activity#GO:0003713;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;transcription coregulator activity#GO:0003712 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;response to hormone#GO:0009725;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;positive regulation of transcription by RNA polymerase II#GO:0045944 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000021183.3|UniProtKB=H9H7W7 H9H7W7 SIRT3 PTHR11085:SF5 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-3, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;NAD-dependent protein lysine deacetylase activity#GO:0034979;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824;deacylase activity#GO:0160215;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;acyltransferase activity#GO:0016746 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000014749.4|UniProtKB=F6YN29 F6YN29 MKS1 PTHR12968:SF4 B9 DOMAIN-CONTAINING TECTONIC-LIKE COMPLEX MEMBER MKS1 cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;ciliary transition zone#GO:0035869 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000008303.5|UniProtKB=A0A5F8GAC2 A0A5F8GAC2 CTR9 PTHR14027:SF2 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000005635.4|UniProtKB=F7CEZ2 F7CEZ2 DNAJC25 PTHR44176:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 25 DNAJ HOMOLOG SUBFAMILY C MEMBER 25 protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000010746.5|UniProtKB=F7FWT8 F7FWT8 JARID2 PTHR10694:SF149 LYSINE-SPECIFIC DEMETHYLASE PROTEIN JUMONJI histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;protein demethylase activity#GO:0140457;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491;histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000047230.1|UniProtKB=K7E3H7 K7E3H7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000015468.3|UniProtKB=F6WWU8 F6WWU8 YIPF4 PTHR21236:SF7 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF4 organelle organization#GO:0006996;membrane fusion#GO:0061025;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;cellular component organization#GO:0016043;Golgi organization#GO:0007030;vesicle fusion#GO:0006906;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000018129.4|UniProtKB=F7DGU1 F7DGU1 KLHL32 PTHR45632:SF45 LD33804P KELCH-LIKE PROTEIN 32 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 transferase complex#GO:1990234;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000008624.3|UniProtKB=F6PH00 F6PH00 HDAC11 PTHR10625:SF23 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 11 histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096;histone modifying activity#GO:0140993 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000011382.4|UniProtKB=A0A5F8HEA8 A0A5F8HEA8 PTHR11736:SF14 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN NSE3 HOMOLOG, SMC5-SMC6 COMPLEX COMPONENT cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013182.4|UniProtKB=F6ZL24 F6ZL24 ST8SIA2 PTHR11987:SF30 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-2,8-SIALYLTRANSFERASE 8B sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000006462.4|UniProtKB=A0A5F8GW83 A0A5F8GW83 IFT122 PTHR12764:SF4 WD REPEAT DOMAIN-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 122 HOMOLOG intraciliary transport#GO:0042073;protein localization to cilium#GO:0061512;microtubule-based movement#GO:0007018;protein localization to organelle#GO:0033365;intraciliary retrograde transport#GO:0035721;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;non-motile cilium assembly#GO:1905515;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031 cilium#GO:0005929;intraciliary transport particle#GO:0030990;non-motile cilium#GO:0097730;intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000008030.4|UniProtKB=F7CKM9 F7CKM9 HAL PTHR10362:SF85 HISTIDINE AMMONIA-LYASE HISTIDINE AMMONIA-LYASE catalytic activity#GO:0003824;lyase activity#GO:0016829 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 lyase#PC00144 MONDO|Ensembl=ENSMODG00000028058.2|UniProtKB=K7E4W0 K7E4W0 PTHR23037:SF29 CYTOKINE RECEPTOR INTERLEUKIN-9 RECEPTOR transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;growth factor binding#GO:0019838;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;response to peptide#GO:1901652;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;cytokine-mediated signaling pathway#GO:0019221;immune system process#GO:0002376;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;interleukin-9-mediated signaling pathway#GO:0038113;adaptive immune response#GO:0002250;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012445.4|UniProtKB=F6PJE9 F6PJE9 LOC103098396 PTHR24238:SF69 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 165 neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000029717.2|UniProtKB=K7E577 K7E577 LOC103097229 PTHR11430:SF124 LIPOCALIN LIPOCALIN 1-LIKE PROTEIN 1-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000025667.2|UniProtKB=F6XDC3 F6XDC3 PTHR26451:SF68 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 6K2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000006704.3|UniProtKB=F7DGX6 F7DGX6 TPH1 PTHR11473:SF23 AROMATIC AMINO ACID HYDROXYLASE TRYPTOPHAN 5-HYDROXYLASE 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 biosynthetic process#GO:0009058;serotonin biosynthetic process#GO:0042427;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430;phenol-containing compound metabolic process#GO:0018958;phenol-containing compound biosynthetic process#GO:0046189;serotonin metabolic process#GO:0042428;metabolic process#GO:0008152 neuron projection#GO:0043005;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 5-Hydroxytryptamine biosynthesis#P04371>Tryptophan hydroxylase#P04399 MONDO|Ensembl=ENSMODG00000018926.3|UniProtKB=F7GJV5 F7GJV5 AARS2 PTHR11777:SF8 ALANYL-TRNA SYNTHETASE ALANINE--TRNA LIGASE, MITOCHONDRIAL hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;carboxylic ester hydrolase activity#GO:0052689;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;deacylase activity#GO:0160215;ligase activity#GO:0016874;hydrolase activity, acting on ester bonds#GO:0016788 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170 aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000009691.4|UniProtKB=F6YBE5 F6YBE5 STARD13 PTHR12659:SF6 RHO-TYPE GTPASE ACTIVATING PROTEIN STAR-RELATED LIPID TRANSFER PROTEIN 13 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of small GTPase mediated signal transduction#GO:0051056;cellular component organization or biogenesis#GO:0071840;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;actin cytoskeleton organization#GO:0030036;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 GTPase-activating protein#PC00257;G-protein modulator#PC00022 PDGF signaling pathway#P00047>Rho#P01174 MONDO|Ensembl=ENSMODG00000003341.4|UniProtKB=F7CU00 F7CU00 MYSM1 PTHR12802:SF189 SWI/SNF COMPLEX-RELATED DEUBIQUITINASE MYSM1 transcription regulator activity#GO:0140110;histone binding#GO:0042393;binding#GO:0005488;transcription coregulator activity#GO:0003712;protein binding#GO:0005515;transcription coactivator activity#GO:0003713 regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;positive regulation of RNA metabolic process#GO:0051254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000008462.2|UniProtKB=F7GEW9 F7GEW9 LOC100016903 PTHR26450:SF422 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011161.4|UniProtKB=F7AN11 F7AN11 MAP3K14 PTHR48016:SF9 MAP KINASE KINASE KINASE SSK2-RELATED-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 14 intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>NIK#P00324;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;CCKR signaling map#P06959>MAP3K14#P07063 MONDO|Ensembl=ENSMODG00000013085.4|UniProtKB=A0A5F8G6M1 A0A5F8G6M1 LRFN5 PTHR45842:SF10 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 5 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of cellular component organization#GO:0051128;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;synapse organization#GO:0050808;cell adhesion#GO:0007155;regulation of biological quality#GO:0065008;synaptic membrane adhesion#GO:0099560;regulation of synapse structure or activity#GO:0050803;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;regulation of synapse assembly#GO:0051963;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cell periphery#GO:0071944;glutamatergic synapse#GO:0098978;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;cell surface#GO:0009986;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;GABA-ergic synapse#GO:0098982;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000024917.2|UniProtKB=F6SFQ5 F6SFQ5 PTHR35265:SF1 LEUKOSIALIN LEUKOSIALIN MONDO|Ensembl=ENSMODG00000010830.3|UniProtKB=F7BE29 F7BE29 CCR4 PTHR10489:SF608 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 4 cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515 immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;chemotaxis#GO:0006935;cell communication#GO:0007154;cell chemotaxis#GO:0060326;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;signaling#GO:0023052;locomotion#GO:0040011;response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000041279.1|UniProtKB=H9H9G6 H9H9G6 PTHR24390:SF290 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 184 double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000000658.4|UniProtKB=F6STK5 F6STK5 EDNRA PTHR46099:SF2 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ENDOTHELIN-1 RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of biological quality#GO:0065008;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;pigmentation#GO:0043473;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;biological regulation#GO:0065007;developmental pigmentation#GO:0048066;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;regulation of anatomical structure size#GO:0090066 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 Endothelin signaling pathway#P00019>ET-RA/B#P00580 MONDO|Ensembl=ENSMODG00000037726.1|UniProtKB=A0A5F8GJN7 A0A5F8GJN7 PTHR33426:SF30 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000039073.1|UniProtKB=A0A5F8HE14 A0A5F8HE14 LOC100023328 PTHR26451:SF52 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 12D2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000015891.3|UniProtKB=F7B375 F7B375 RNPS1 PTHR15481:SF2 RIBONUCLEIC ACID BINDING PROTEIN S1 RNA-BINDING PROTEIN WITH SERINE-RICH DOMAIN 1 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000020718.4|UniProtKB=A0A5F8GU45 A0A5F8GU45 TSPAN5 PTHR19282:SF63 TETRASPANIN TETRASPANIN-5 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019858.4|UniProtKB=A0A5F8GBV5 A0A5F8GBV5 TTC17 PTHR16091:SF1 TTC17 PROTEIN TETRATRICOPEPTIDE REPEAT PROTEIN 17 cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cell projection organization#GO:0030030;actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629 MONDO|Ensembl=ENSMODG00000017926.4|UniProtKB=F7EKB4 F7EKB4 CDK19 PTHR24056:SF570 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 19 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911;mediator complex#GO:0016592;cytosol#GO:0005829;nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000051040.1|UniProtKB=A0A5F8H765 A0A5F8H765 PTHR11346:SF97 GALECTIN GALECTIN-1 extracellular matrix binding#GO:0050840;carbohydrate binding#GO:0030246;protein binding#GO:0005515;laminin binding#GO:0043236;binding#GO:0005488;oligosaccharide binding#GO:0070492 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000050951.1|UniProtKB=A0A5F8GWK4 A0A5F8GWK4 PTHR23503:SF32 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 5 sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;carbohydrate transport#GO:0008643;import into cell#GO:0098657;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659;carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180;import across plasma membrane#GO:0098739 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000010788.2|UniProtKB=F7CIH5 F7CIH5 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000010701.3|UniProtKB=F7GH91 F7GH91 GATAD1 PTHR13340:SF2 GATA ZINC FINGER DOMAIN-CONTAINING GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000018283.4|UniProtKB=F6Q6D3 F6Q6D3 PTHR12126:SF11 NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL protein-containing complex binding#GO:0044877;binding#GO:0005488 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ketone metabolic process#GO:0042180;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000007540.5|UniProtKB=F7GAU6 F7GAU6 FNDC1 PTHR23197:SF8 TARSH-RELATED FIBRONECTIN DOMAIN-CONTAINING FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 1 hormone activity#GO:0005179;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 skeletal muscle tissue development#GO:0007519;muscle structure development#GO:0061061;tissue development#GO:0009888;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;muscle organ development#GO:0007517;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;animal organ development#GO:0048513 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000005905.4|UniProtKB=F6XD41 F6XD41 BATF PTHR23351:SF14 FOS TRANSCRIPTION FACTOR-RELATED BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 basic leucine zipper transcription factor#PC00056 MONDO|Ensembl=ENSMODG00000015567.4|UniProtKB=F6RF07 F6RF07 KCMF1 PTHR12268:SF13 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000050952.1|UniProtKB=A0A5F8H510 A0A5F8H510 TMEM247 PTHR36691:SF1 TRANSMEMBRANE PROTEIN 247 TRANSMEMBRANE PROTEIN 247 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000046749.1|UniProtKB=A0A5F8GV88 A0A5F8GV88 PTHR47499:SF2 SERINE PROTEASE INHIBITOR KAZAL-TYPE 7 SPINK7 SERINE PROTEASE INHIBITOR KAZAL-TYPE 9 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;biological regulation#GO:0065007;negative regulation of protein metabolic process#GO:0051248;regulation of primary metabolic process#GO:0080090;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000010388.4|UniProtKB=F7AUT2 F7AUT2 CRYBB3 PTHR11818:SF13 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN B3 structural molecule activity#GO:0005198 system process#GO:0003008;multicellular organism development#GO:0007275;animal organ development#GO:0048513;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;sensory organ development#GO:0007423;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856;sensory perception#GO:0007600;nervous system process#GO:0050877;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;visual system development#GO:0150063;visual perception#GO:0007601;sensory perception of light stimulus#GO:0050953 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000015267.3|UniProtKB=F6TMQ9 F6TMQ9 STK16 PTHR45998:SF9 SERINE/THREONINE-PROTEIN KINASE 16 SERINE_THREONINE-PROTEIN KINASE 16 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000023599.3|UniProtKB=F7FPT7 F7FPT7 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011214.2|UniProtKB=F6S7W5 F6S7W5 PCDHB1 PTHR24028:SF118 CADHERIN-87A PROTOCADHERIN BETA-1 cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000025383.2|UniProtKB=F6Z9C2 F6Z9C2 PTHR19282:SF51 TETRASPANIN TETRASPANIN-32 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010338.4|UniProtKB=F6S926 F6S926 ADAM22 PTHR11905:SF14 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 22 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000020959.4|UniProtKB=F6SNW9 F6SNW9 PRDM15 PTHR16515:SF34 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 15 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000038204.1|UniProtKB=A0A5F8G869 A0A5F8G869 B3GALT5 PTHR11214:SF265 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 5 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000014008.4|UniProtKB=A0A5F8GR23 A0A5F8GR23 MCF2 PTHR22826:SF146 RHO GUANINE EXCHANGE FACTOR-RELATED PROTO-ONCOGENE DBL GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;dendrite development#GO:0016358;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000004700.4|UniProtKB=F6TQ91 F6TQ91 SIKE1 PTHR12186:SF4 SIKE FAMILY MEMBER SUPPRESSOR OF IKBKE 1 MONDO|Ensembl=ENSMODG00000011180.3|UniProtKB=F6ZZ86 F6ZZ86 LOC100021334 PTHR26450:SF79 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000047907.1|UniProtKB=A0A5F8HH66 A0A5F8HH66 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000003153.4|UniProtKB=A0A5F8GE37 A0A5F8GE37 MAGI1 PTHR10316:SF12 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of protein localization to membrane#GO:1905475 cell junction#GO:0030054;adherens junction#GO:0005912;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cell-cell junction#GO:0005911 MONDO|Ensembl=ENSMODG00000016954.4|UniProtKB=F6V673 F6V673 MEX3A PTHR23285:SF2 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING PROTEIN MEX3A RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000009300.4|UniProtKB=F6YXD5 F6YXD5 ST6GALNAC2 PTHR45941:SF5 ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 2-LIKE-RELATED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 2 glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238 MONDO|Ensembl=ENSMODG00000012103.4|UniProtKB=A0A5F8H6I6 A0A5F8H6I6 PTHR19282:SF48 TETRASPANIN TETRASPANIN-3 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020998.4|UniProtKB=F6RJX5 F6RJX5 ADAMTS5 PTHR13723:SF37 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 5 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000006439.4|UniProtKB=F7EYV1 F7EYV1 ABHD12 PTHR12277:SF61 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN LYSOPHOSPHATIDYLSERINE LIPASE ABHD12 catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;phospholipase activity#GO:0120569;hydrolase activity#GO:0016787 cellular process#GO:0009987;lipid catabolic process#GO:0016042;organophosphate metabolic process#GO:0019637;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerophospholipid catabolic process#GO:0046475;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;glycerolipid catabolic process#GO:0046503;organophosphate catabolic process#GO:0046434 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000019454.4|UniProtKB=F6RXC0 F6RXC0 ITGA2 PTHR23220:SF23 INTEGRIN ALPHA INTEGRIN ALPHA-2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell surface receptor signaling pathway#GO:0007166;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863 MONDO|Ensembl=ENSMODG00000017082.4|UniProtKB=A0A5F8HHQ1 A0A5F8HHQ1 ZCCHC17 PTHR15838:SF1 NUCLEOLAR PROTEIN OF 40 KDA ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 17 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of RNA stability#GO:0043487;RNA stabilization#GO:0043489;negative regulation of catabolic process#GO:0009895;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252 MONDO|Ensembl=ENSMODG00000012155.4|UniProtKB=F7CYR8 F7CYR8 LAMC3 PTHR10574:SF240 NETRIN/LAMININ-RELATED LAMININ SUBUNIT GAMMA-3 tissue development#GO:0009888;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 MONDO|Ensembl=ENSMODG00000008541.4|UniProtKB=F7DH29 F7DH29 KCNK1 PTHR11003:SF353 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 1 potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000012214.4|UniProtKB=F7CE20 F7CE20 PGAP1 PTHR15495:SF7 NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED GPI INOSITOL-DEACYLASE deacylase activity#GO:0160215;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000050404.1|UniProtKB=A0A5F8GLK7 A0A5F8GLK7 MCUR1 PTHR14360:SF11 PROTEIN FMP32, MITOCHONDRIAL MITOCHONDRIAL CALCIUM UNIPORTER REGULATOR 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;homeostatic process#GO:0042592;mitochondrial calcium ion homeostasis#GO:0051560;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588 mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000038822.1|UniProtKB=A0A5F8GI30 A0A5F8GI30 BMT2 PTHR21008:SF0 S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1-RELATED S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1 molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to nutrient levels#GO:0031667;response to acid chemical#GO:0001101;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;regulation of TORC1 signaling#GO:1903432;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051 MONDO|Ensembl=ENSMODG00000005208.4|UniProtKB=A0A5F8GR63 A0A5F8GR63 IDH3B PTHR11835:SF84 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 tricarboxylic acid cycle#GO:0006099;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;alcohol metabolic process#GO:0006066;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000028424.2|UniProtKB=A0A5F8GCJ9 A0A5F8GCJ9 AOX4 PTHR45444:SF3 XANTHINE DEHYDROGENASE XANTHINE DEHYDROGENASE MONDO|Ensembl=ENSMODG00000019572.5|UniProtKB=F6Z1R6 F6Z1R6 WHRN PTHR23116:SF37 PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED WHIRLIN anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;inner ear receptor cell stereocilium organization#GO:0060122;cell development#GO:0048468;sensory organ morphogenesis#GO:0090596;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;sensory perception of sound#GO:0007605;cell differentiation#GO:0030154;nervous system process#GO:0050877;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;ear development#GO:0043583;neuron development#GO:0048666;cellular process#GO:0009987;hair cell differentiation#GO:0035315;inner ear morphogenesis#GO:0042472;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;embryo development#GO:0009790;neuron differentiation#GO:0030182;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;animal organ morphogenesis#GO:0009887;embryonic organ development#GO:0048568;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;system development#GO:0048731;anatomical structure development#GO:0048856;inner ear development#GO:0048839;plasma membrane bounded cell projection organization#GO:0120036;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;epithelium development#GO:0060429;developmental process#GO:0032502;epidermis development#GO:0008544;sensory organ development#GO:0007423;neurogenesis#GO:0022008;system process#GO:0003008;cellular developmental process#GO:0048869 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;stereocilium#GO:0032420 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000018385.4|UniProtKB=F6QV19 F6QV19 LOC100021123 PTHR11728:SF46 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)] catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000039025.1|UniProtKB=A0A5F8HIV8 A0A5F8HIV8 TOMM5 PTHR28436:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM5 HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM5 HOMOLOG primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000021417.4|UniProtKB=F7CBP5 F7CBP5 LDLRAD4 PTHR16514:SF4 LOW DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING 4A LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 4 protein binding#GO:0005515;binding#GO:0005488 regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 MONDO|Ensembl=ENSMODG00000023964.2|UniProtKB=F7F7A3 F7F7A3 PTHR12887:SF12 NANOS PROTEIN NANOS HOMOLOG 3 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 oogenesis#GO:0048477;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;negative regulation of metabolic process#GO:0009892;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell differentiation#GO:0030154;gamete generation#GO:0007276;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of translation#GO:0017148;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of protein metabolic process#GO:0051248;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953 cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000019481.5|UniProtKB=F6WAD0 F6WAD0 CCNO PTHR10177:SF401 CYCLINS CYCLIN-O cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000003989.4|UniProtKB=F7DSQ5 F7DSQ5 ANKRD2 PTHR24126:SF3 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 2 binding#GO:0005488;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000004385.4|UniProtKB=F6SVX1 F6SVX1 NDE1 PTHR10921:SF2 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 chromosome segregation#GO:0007059;microtubule organizing center organization#GO:0031023;protein-containing complex organization#GO:0043933;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;cytoskeleton organization#GO:0007010;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;microtubule-based transport#GO:0099111;establishment or maintenance of cell polarity#GO:0007163;nuclear division#GO:0000280;cellular localization#GO:0051641;spindle localization#GO:0051653;protein-containing complex assembly#GO:0065003;centrosome cycle#GO:0007098;protein polymerization#GO:0051258;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;centrosome localization#GO:0051642;establishment of organelle localization#GO:0051656;transport#GO:0006810;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;mitotic cell cycle process#GO:1903047;vesicle cytoskeletal trafficking#GO:0099518;microtubule polymerization#GO:0046785;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;transport along microtubule#GO:0010970;vesicle localization#GO:0051648;establishment of spindle localization#GO:0051293;microtubule polymerization or depolymerization#GO:0031109;cell migration#GO:0016477;cytoskeleton-dependent intracellular transport#GO:0030705;organelle localization#GO:0051640;supramolecular fiber organization#GO:0097435;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;establishment of cell polarity#GO:0030010;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;microtubule-based movement#GO:0007018;cell motility#GO:0048870 membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;kinetochore#GO:0000776 MONDO|Ensembl=ENSMODG00000011701.4|UniProtKB=F7G3R4 F7G3R4 HBEGF PTHR10740:SF4 TRANSFORMING GROWTH FACTOR ALPHA PROHEPARIN-BINDING EGF-LIKE GROWTH FACTOR signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;carbohydrate derivative binding#GO:0097367;heparin binding#GO:0008201;protein binding#GO:0005515;molecular function activator activity#GO:0140677;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;signaling receptor binding#GO:0005102 cell surface receptor signaling pathway#GO:0007166;positive regulation of mitotic nuclear division#GO:0045840;regulation of mitotic nuclear division#GO:0007088;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cell cycle#GO:0045787;regulation of nuclear division#GO:0051783;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;epidermal growth factor receptor signaling pathway#GO:0007173;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cellular component organization#GO:0051130;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of organelle organization#GO:0010638;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 growth factor#PC00112 CCKR signaling map#P06959>HBEGF#P07025;CCKR signaling map#P06959>HBEGF#G07261;CCKR signaling map#P06959>HBEGF#G06968;EGF receptor signaling pathway#P00018>EGF#P00549;CCKR signaling map#P06959>Pro HBEGF#P07182 MONDO|Ensembl=ENSMODG00000012290.4|UniProtKB=F7GF41 F7GF41 PTHR10751:SF117 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 6 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 G-protein#PC00020;heterotrimeric G-protein#PC00117 MONDO|Ensembl=ENSMODG00000028633.2|UniProtKB=A0A5F8GGR6 A0A5F8GGR6 PTHR35256:SF1 CHROMOSOME 8 OPEN READING FRAME 48 SIMILAR TO HUMAN CHROMOSOME 8 OPEN READING FRAME 48 MONDO|Ensembl=ENSMODG00000012789.4|UniProtKB=F7EFY6 F7EFY6 NEK7 PTHR43289:SF2 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;positive regulation of signal transduction#GO:0009967;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;positive regulation of cellular component biogenesis#GO:0044089;regulation of response to external stimulus#GO:0032101;positive regulation of pattern recognition receptor signaling pathway#GO:0062208;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;positive regulation of response to external stimulus#GO:0032103 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000014232.3|UniProtKB=F6T964 F6T964 HSD17B8 PTHR42760:SF141 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;binding#GO:0005488;catalytic activity#GO:0003824;small molecule binding#GO:0036094;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;regulation of hormone levels#GO:0010817;small molecule metabolic process#GO:0044281;hormone biosynthetic process#GO:0042446;oxoacid metabolic process#GO:0043436;estrogen metabolic process#GO:0008210;regulation of biological quality#GO:0065008;cellular process#GO:0009987;hormone metabolic process#GO:0042445;lipid biosynthetic process#GO:0008610;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;biological regulation#GO:0065007;fatty acid biosynthetic process#GO:0006633;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;steroid biosynthetic process#GO:0006694 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000003329.4|UniProtKB=A0A5F8G241 A0A5F8G241 KCNK2 PTHR11003:SF21 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 2 voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000041860.1|UniProtKB=A0A5F8H7L1 A0A5F8H7L1 HAND2 PTHR23349:SF41 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST HEART- AND NEURAL CREST DERIVATIVES-EXPRESSED PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;heart development#GO:0007507;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000014730.4|UniProtKB=A0A5F8GPT9 A0A5F8GPT9 DAZL PTHR11176:SF4 BOULE-RELATED DELETED IN AZOOSPERMIA-LIKE translation regulator activity#GO:0045182 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;negative regulation of catabolic process#GO:0009895;positive regulation of translation#GO:0045727;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of translational initiation#GO:0006446;positive regulation of protein metabolic process#GO:0051247;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA stabilization#GO:0043489;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000004170.2|UniProtKB=F6QPL1 F6QPL1 PTHR10540:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED COP9 SIGNALOSOME COMPLEX SUBUNIT 6 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000015389.4|UniProtKB=A0A5F8HKZ6 A0A5F8HKZ6 IQUB PTHR21074:SF0 IQ AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN IQ MOTIF AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;acrosomal vesicle#GO:0001669;cilium#GO:0005929;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;endomembrane system#GO:0012505;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000012238.4|UniProtKB=F6Z6D0 F6Z6D0 ANKRD44 PTHR24123:SF82 ANKYRIN REPEAT-CONTAINING SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY ANKYRIN REPEAT SUBUNIT B molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000047538.1|UniProtKB=A0A5F8GK48 A0A5F8GK48 PTHR23169:SF24 ENVOPLAKIN DYSTONIN protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 intermediate filament-based process#GO:0045103;cellular component organization or biogenesis#GO:0071840;wound healing#GO:0042060;organelle organization#GO:0006996;response to wounding#GO:0009611;cellular component organization#GO:0016043;response to stress#GO:0006950;cellular process#GO:0009987;response to stimulus#GO:0050896;intermediate filament cytoskeleton organization#GO:0045104;cytoskeleton organization#GO:0007010 focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell junction#GO:0030054 intermediate filament#PC00129;intermediate filament binding protein#PC00130 MONDO|Ensembl=ENSMODG00000009541.3|UniProtKB=F7C428 F7C428 AP5B1 PTHR34033:SF1 AP-5 COMPLEX SUBUNIT BETA-1 AP-5 COMPLEX SUBUNIT BETA-1 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;membrane protein complex#GO:0098796 MONDO|Ensembl=ENSMODG00000036415.1|UniProtKB=A0A5F8HIM6 A0A5F8HIM6 PTHR24071:SF0 RAN GTPASE GTP-BINDING NUCLEAR PROTEIN RAN ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;protein transport#GO:0015031;protein import into nucleus#GO:0006606;ribosome biogenesis#GO:0042254;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit export from nucleus#GO:0000055;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;gene expression#GO:0010467;protein export from nucleus#GO:0006611;cellular component biogenesis#GO:0044085;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;organelle localization#GO:0051640;ribosome localization#GO:0033750;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;RNA export from nucleus#GO:0006405;transport#GO:0006810;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;macromolecule biosynthetic process#GO:0009059 nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000003465.4|UniProtKB=A0A5F8GE17 A0A5F8GE17 LOC100019605 PTHR15172:SF1 GALACTOCEREBROSIDASE GALACTOCEREBROSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;ceramide metabolic process#GO:0006672;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665 intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 galactosidase#PC00104;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000048963.1|UniProtKB=A0A5F8GNA3 A0A5F8GNA3 PTHR18860:SF131 14-3-3 PROTEIN 14-3-3 DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000278.3|UniProtKB=F6WB40 F6WB40 PANX1 PTHR15759:SF5 PANNEXIN PANNEXIN-1 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267 cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;cellular process#GO:0009987;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000016755.4|UniProtKB=A0A5F8GKI8 A0A5F8GKI8 PTHR11905:SF21 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 7 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000011734.4|UniProtKB=F7FSR7 F7FSR7 LGALS3 PTHR11346:SF26 GALECTIN GALECTIN-3 protein binding#GO:0005515;extracellular matrix binding#GO:0050840;carbohydrate binding#GO:0030246;protein-containing complex binding#GO:0044877;oligosaccharide binding#GO:0070492;binding#GO:0005488;laminin binding#GO:0043236 negative regulation of cellular component organization#GO:0051129;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell motility#GO:0048870;negative regulation of transport#GO:0051051;regulation of metal ion transport#GO:0010959;locomotion#GO:0040011;regulation of cell communication#GO:0010646;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;chemotaxis#GO:0006935;macrophage chemotaxis#GO:0048246;cell chemotaxis#GO:0060326;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;negative regulation of response to stimulus#GO:0048585;cell migration#GO:0016477;regulation of monoatomic ion transport#GO:0043269;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of calcium ion transport#GO:0051924;negative regulation of cellular process#GO:0048523;leukocyte migration#GO:0050900;regulation of response to stimulus#GO:0048583;leukocyte chemotaxis#GO:0030595;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;granulocyte chemotaxis#GO:0071621;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;mononuclear cell migration#GO:0071674;negative regulation of signaling#GO:0023057;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;positive chemotaxis#GO:0050918;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;negative regulation of programmed cell death#GO:0043069;granulocyte migration#GO:0097530;taxis#GO:0042330;response to chemical#GO:0042221;neutrophil migration#GO:1990266;negative regulation of signal transduction#GO:0009968;neutrophil chemotaxis#GO:0030593;regulation of apoptotic process#GO:0042981;regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;regulation of localization#GO:0032879 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000012601.4|UniProtKB=F6PI65 F6PI65 IPO8 PTHR10997:SF26 IMPORTIN-7, 8, 11 IMPORTIN-8 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 cellular localization#GO:0051641;localization#GO:0051179;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000023475.3|UniProtKB=A0A5F8GSE7 A0A5F8GSE7 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000017745.4|UniProtKB=F7EKT5 F7EKT5 MTF1 PTHR46179:SF25 ZINC FINGER PROTEIN METAL RESPONSE ELEMENT-BINDING TRANSCRIPTION FACTOR-1, ISOFORM C regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000009365.4|UniProtKB=A0A5F8GET1 A0A5F8GET1 CACUL1 PTHR46636:SF1 CDK2-ASSOCIATED AND CULLIN DOMAIN-CONTAINING PROTEIN 1 CDK2-ASSOCIATED AND CULLIN DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488 cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047 MONDO|Ensembl=ENSMODG00000039663.1|UniProtKB=A0A5F8GJM3 A0A5F8GJM3 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000013305.4|UniProtKB=F6UYE0 F6UYE0 USP19 PTHR21646:SF24 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 19 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000009292.3|UniProtKB=F6YXL5 F6YXL5 PTHR28544:SF1 PROTEIN FAM45A-RELATED DENN DOMAIN-CONTAINING PROTEIN 10-RELATED GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;macromolecule localization#GO:0033036;protein transport#GO:0015031;regulation of localization#GO:0032879;intracellular protein localization#GO:0008104;regulation of transport#GO:0051049;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;late endosome#GO:0005770;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000028622.1|UniProtKB=K7E0G5 K7E0G5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000028615.2|UniProtKB=K7E4Z8 K7E4Z8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000025449.2|UniProtKB=A0A5F8GQQ9 A0A5F8GQQ9 PTHR24028:SF123 CADHERIN-87A CADHERIN-RELATED FAMILY MEMBER 4 cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;cadherin#PC00057 MONDO|Ensembl=ENSMODG00000025583.2|UniProtKB=F6U2H5 F6U2H5 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signaling#GO:0023052;biological regulation#GO:0065007;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000021209.4|UniProtKB=A0A5F8GW25 A0A5F8GW25 RHBDD1 PTHR43066:SF14 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 4 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;response to unfolded protein#GO:0006986;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;response to stress#GO:0006950;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000045139.1|UniProtKB=F7GIG8 F7GIG8 LOC100618060 PTHR48002:SF74 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024614.2|UniProtKB=F7CPH0 F7CPH0 PTHR11477:SF1 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 1 transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000010624.3|UniProtKB=F7DP98 F7DP98 LOC107651329 PTHR26451:SF98 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10T2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000017721.4|UniProtKB=F7FHF4 F7FHF4 GOLM2 PTHR15896:SF7 GOLGI PHOSPHOPROTEIN 2/GP73-RELATED PROTEIN GOLM2 MONDO|Ensembl=ENSMODG00000001813.4|UniProtKB=F6T5R4 F6T5R4 CLHC1 PTHR10292:SF11 CLATHRIN HEAVY CHAIN RELATED CLATHRIN HEAVY CHAIN LINKER DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810 membrane#GO:0016020;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;membrane coat#GO:0030117;coated membrane#GO:0048475 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000024402.2|UniProtKB=F6Z3U9 F6Z3U9 CTXN2 PTHR16736:SF2 CORTEXIN-1-RELATED CORTEXIN-2 MONDO|Ensembl=ENSMODG00000008247.4|UniProtKB=F7FBB7 F7FBB7 PTHR23226:SF128 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 30 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005386.4|UniProtKB=F7GGF7 F7GGF7 NECTIN4 PTHR23277:SF11 NECTIN-RELATED NECTIN-4 protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488 cell adhesion#GO:0007155;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609 anchoring junction#GO:0070161;adherens junction#GO:0005912;cell junction#GO:0030054;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000006136.4|UniProtKB=A0A5F8GWF5 A0A5F8GWF5 ATG7 PTHR10953:SF3 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7 nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity#GO:0016874;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;Atg12 activating enzyme activity#GO:0019778;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular response to stimulus#GO:0051716;protein modification process#GO:0036211;primary metabolic process#GO:0044238;response to starvation#GO:0042594;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;organelle assembly#GO:0070925;vacuole organization#GO:0007033;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;response to nutrient levels#GO:0031667;post-translational protein modification#GO:0043687;macroautophagy#GO:0016236;cellular response to nutrient levels#GO:0031669;autophagy of mitochondrion#GO:0000422;cellular response to starvation#GO:0009267;macromolecule metabolic process#GO:0043170;mitophagy#GO:0000423;protein modification by small protein conjugation#GO:0032446;cellular component organization#GO:0016043;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;process utilizing autophagic mechanism#GO:0061919;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component assembly#GO:0022607;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;phagophore assembly site#GO:0000407 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 MONDO|Ensembl=ENSMODG00000016275.3|UniProtKB=F7BGQ0 F7BGQ0 WDR12 PTHR19855:SF40 WD40 REPEAT PROTEIN 12, 37 RIBOSOME BIOGENESIS PROTEIN WDR12 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;90S preribosome#GO:0030686;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000001795.4|UniProtKB=F6WIC1 F6WIC1 CDK18 PTHR24056:SF52 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 18 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000014600.4|UniProtKB=F6ZEQ2 F6ZEQ2 DDX10 PTHR24031:SF54 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX10-RELATED RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000007003.4|UniProtKB=F7BKF6 F7BKF6 RBM47 PTHR21245:SF6 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 47 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000001959.3|UniProtKB=F6VJ46 F6VJ46 SLC25A41 PTHR24089:SF181 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL CARRIER PROTEIN SCAMC-3L phosphate transmembrane transporter activity#GO:0005315;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;purine nucleotide transmembrane transporter activity#GO:0015216 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000015887.3|UniProtKB=F7B3B0 F7B3B0 ADCY3 PTHR45627:SF30 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 3 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824 signal transduction#GO:0007165;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cyclic purine nucleotide metabolic process#GO:0052652;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;cyclic nucleotide biosynthetic process#GO:0009190;purine-containing compound biosynthetic process#GO:0072522;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 adenylate cyclase#PC00043 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 MONDO|Ensembl=ENSMODG00000019218.3|UniProtKB=F7FMQ8 F7FMQ8 EVI2A PTHR15568:SF0 ECOTROPIC VIRAL INTEGRATION SITE 2A PROTEIN EVI2A transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025605.2|UniProtKB=F6QC01 F6QC01 PTHR31402:SF2 UPF0711 PROTEIN C18ORF21 RIBONUCLEASE MRP PROTEIN SUBUNIT P24 MONDO|Ensembl=ENSMODG00000010096.4|UniProtKB=A0A5F8GBF8 A0A5F8GBF8 PPP2R2B PTHR11871:SF1 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B BETA ISOFORM protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629 MONDO|Ensembl=ENSMODG00000006458.3|UniProtKB=F7FGU3 F7FGU3 ENDOG PTHR13966:SF5 ENDONUCLEASE RELATED ENDONUCLEASE G, MITOCHONDRIAL catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309;DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;execution phase of apoptosis#GO:0097194;cell death#GO:0008219;apoptotic process#GO:0006915;catabolic process#GO:0009056 mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;organelle membrane#GO:0031090 Apoptosis signaling pathway#P00006>endoG#P00279 MONDO|Ensembl=ENSMODG00000023335.3|UniProtKB=F6YHU9 F6YHU9 AGO1 PTHR22891:SF17 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;binding#GO:0005488;nuclease activity#GO:0004518;RNA binding#GO:0003723 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;RNA biosynthetic process#GO:0032774 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000019150.3|UniProtKB=F7BK78 F7BK78 ZNF830 PTHR13278:SF0 ZINC FINGER PROTEIN 830 ZINC FINGER PROTEIN 830 response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;mitotic DNA replication checkpoint signaling#GO:0033314;regulation of biological process#GO:0050789;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;DNA replication checkpoint signaling#GO:0000076;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;cellular response to stimulus#GO:0051716;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;biological regulation#GO:0065007;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;mitotic G2/M transition checkpoint#GO:0044818;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000005762.4|UniProtKB=F6QD91 F6QD91 ERG28 PTHR15451:SF19 ERGOSTEROL BIOSYNTHETIC PROTEIN 28-RELATED ERGOSTEROL BIOSYNTHETIC PROTEIN 28 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000024303.1|UniProtKB=F7EI94 F7EI94 LOC100024252 PTHR48018:SF75 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010914.3|UniProtKB=F7F5E5 F7F5E5 NPPA PTHR14066:SF2 ATRIAL NATRIURETIC FACTOR PRECURSOR NATRIURETIC PEPTIDES A receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179 regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cyclic nucleotide biosynthetic process#GO:0009190;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;regulation of biological quality#GO:0065008;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;regulation of systemic arterial blood pressure#GO:0003073;ribose phosphate biosynthetic process#GO:0046390;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;circulatory system process#GO:0003013;cell communication#GO:0007154;cGMP biosynthetic process#GO:0006182;enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;organophosphate metabolic process#GO:0019637;regulation of blood pressure#GO:0008217;ribonucleotide biosynthetic process#GO:0009260;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;cyclic nucleotide metabolic process#GO:0009187;system process#GO:0003008;nucleoside phosphate biosynthetic process#GO:1901293 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000006527.4|UniProtKB=F7CDQ3 F7CDQ3 MR1 PTHR16675:SF242 MHC CLASS I-RELATED MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I-RELATED PROTEIN 1 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000012582.3|UniProtKB=F6PIZ5 F6PIZ5 PTHR23187:SF1 FLJ44216 PROTEIN-RELATED ELONGIN BC AND POLYCOMB REPRESSIVE COMPLEX 2-ASSOCIATED PROTEIN nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000037711.1|UniProtKB=A0A5F8H4L2 A0A5F8H4L2 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000020750.3|UniProtKB=F6ZZF3 F6ZZF3 TMPRSS11F PTHR24253:SF65 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 11F serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000003693.4|UniProtKB=F7DA02 F7DA02 GRK4 PTHR24355:SF14 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 4 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741 MONDO|Ensembl=ENSMODG00000024100.3|UniProtKB=F6Y1Q6 F6Y1Q6 NUBPL PTHR42961:SF4 IRON-SULFUR PROTEIN NUBPL IRON-SULFUR CLUSTER TRANSFER PROTEIN NUBPL small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000020714.4|UniProtKB=F7BAF0 F7BAF0 LOC100618293 PTHR43880:SF51 ALCOHOL DEHYDROGENASE ALCOHOL DEHYDROGENASE 6B (CLASS V) metal ion binding#GO:0046872;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;ion binding#GO:0043167;transition metal ion binding#GO:0046914;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 lipid metabolic process#GO:0006629;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;biological regulation#GO:0065007;aldehyde catabolic process#GO:0046185;hormone metabolic process#GO:0042445;terpenoid metabolic process#GO:0006721;retinol metabolic process#GO:0042572;isoprenoid metabolic process#GO:0006720;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to toxic substance#GO:0009636;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;cellular response to oxygen-containing compound#GO:1901701;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;regulation of biological quality#GO:0065008;regulation of hormone levels#GO:0010817;cellular detoxification of aldehyde#GO:0110095;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000008311.4|UniProtKB=A0A5F8GCB8 A0A5F8GCB8 TCF12 PTHR11793:SF11 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR 12 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000016702.4|UniProtKB=A0A5F8H5N9 A0A5F8H5N9 EBF2 PTHR10747:SF33 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;P53-like transcription factor#PC00253 MONDO|Ensembl=ENSMODG00000021487.4|UniProtKB=F7G2W6 F7G2W6 SNRPD1 PTHR23338:SF18 SMALL NUCLEAR RIBONUCLEOPROTEIN SM SMALL NUCLEAR RIBONUCLEOPROTEIN SM D1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U5 snRNP#GO:0005682;U2 snRNP#GO:0005686 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000002750.4|UniProtKB=A0A5F8GGW2 A0A5F8GGW2 TRPM3 PTHR13800:SF7 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 3 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000051286.1|UniProtKB=A0A5F8HG88 A0A5F8HG88 LOC100014061 PTHR26452:SF204 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000017310.4|UniProtKB=F6XCP8 F6XCP8 PTHR23358:SF2 METHYLCYTOSINE DIOXYGENASE TET METHYLCYTOSINE DIOXYGENASE TET1 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;catalytic activity, acting on DNA#GO:0140097;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000002716.4|UniProtKB=F7CEC4 F7CEC4 SYT15 PTHR10024:SF234 SYNAPTOTAGMIN SYNAPTOTAGMIN-15-RELATED lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488;phospholipid binding#GO:0005543 vesicle-mediated transport#GO:0016192;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;establishment of localization#GO:0051234;localization#GO:0051179;regulation of secretion#GO:0051046;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of localization#GO:0032879;regulation of transport#GO:0051049;transport#GO:0006810 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 MONDO|Ensembl=ENSMODG00000022843.3|UniProtKB=H9H9N8 H9H9N8 LOC100617613 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011428.5|UniProtKB=F6RKF7 F6RKF7 FZD2 PTHR11309:SF34 FRIZZLED FRIZZLED-2 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 non-canonical Wnt signaling pathway#GO:0035567;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>Fzd#P00189;Cadherin signaling pathway#P00012>Frizzled#P00475;Wnt signaling pathway#P00057>Frizzled#P01428;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 MONDO|Ensembl=ENSMODG00000008130.3|UniProtKB=F7ELT0 F7ELT0 PEX10 PTHR23350:SF0 PEROXISOME ASSEMBLY PROTEIN 10 PEROXISOME BIOGENESIS FACTOR 10 protein import into peroxisome matrix#GO:0016558;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;peroxisomal transport#GO:0043574;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;peroxisome organization#GO:0007031;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular transport#GO:0046907 microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000005595.3|UniProtKB=F7DJD0 F7DJD0 TM4SF5 PTHR14198:SF4 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 5 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000010272.4|UniProtKB=A0A5F8H6Q4 A0A5F8H6Q4 RUNDC3B PTHR46251:SF1 RUN DOMAIN-CONTAINING 3 PROTEIN RUNDC3 RUN DOMAIN-CONTAINING PROTEIN 3B MONDO|Ensembl=ENSMODG00000018571.4|UniProtKB=F7FRP4 F7FRP4 SDHAF4 PTHR28524:SF3 SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL chaperone#PC00072 MONDO|Ensembl=ENSMODG00000045143.1|UniProtKB=A0A5F8GYC4 A0A5F8GYC4 FAM217B PTHR22145:SF3 SI:CH211-266K22.6 PROTEIN FAM217B MONDO|Ensembl=ENSMODG00000013136.4|UniProtKB=F7AZG5 F7AZG5 RXRA PTHR24083:SF39 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR RXR-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;intracellular receptor signaling pathway#GO:0030522;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;hormone-mediated signaling pathway#GO:0009755;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;cellular response to chemical stimulus#GO:0070887;cellular response to hormone stimulus#GO:0032870;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 Vitamin D metabolism and pathway#P04396>RXR#P04602 MONDO|Ensembl=ENSMODG00000048629.1|UniProtKB=A0A5F8GAH3 A0A5F8GAH3 LOC100014763 PTHR45701:SF1 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 1 binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;protein binding#GO:0005515;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484 vesicle fusion#GO:0006906;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;localization#GO:0051179;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;transport#GO:0006810 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Synaptic vesicle trafficking#P05734>Synaptobrevin#P05779;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005 MONDO|Ensembl=ENSMODG00000008520.4|UniProtKB=F7FFK8 F7FFK8 IPO5 PTHR10527:SF5 IMPORTIN BETA IMPORTIN-5 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000000229.4|UniProtKB=F6SYN6 F6SYN6 TFCP2L1 PTHR11037:SF18 TRANSCRIPTION FACTOR CP2 TRANSCRIPTION FACTOR CP2-LIKE PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000014244.3|UniProtKB=F6Y1U2 F6Y1U2 PTHR22747:SF28 NUCLEOPLASMIN NUCLEOPHOSMIN nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393;RNA binding#GO:0003723;protein binding#GO:0005515 ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular localization#GO:0051641;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;ribosomal large subunit export from nucleus#GO:0000055;establishment of organelle localization#GO:0051656;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular component organization#GO:0051128;chromatin remodeling#GO:0006338;ribonucleoprotein complex biogenesis#GO:0022613;regulation of cell cycle#GO:0051726;positive regulation of transcription by RNA polymerase II#GO:0045944;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cell cycle process#GO:0010564;organelle localization#GO:0051640;regulation of microtubule-based process#GO:0032886;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;ribosome localization#GO:0033750;regulation of DNA-templated transcription#GO:0006355;localization#GO:0051179;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;nuclear export#GO:0051168;nuclear transport#GO:0051169;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000017392.3|UniProtKB=A0A5F8GML5 A0A5F8GML5 FNDC5 PTHR14470:SF5 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 5 regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of developmental process#GO:0051094;positive regulation of fat cell differentiation#GO:0045600;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000024976.3|UniProtKB=F6XQ40 F6XQ40 XKR9 PTHR16024:SF13 XK-RELATED PROTEIN XK-RELATED PROTEIN 9 programmed cell death#GO:0012501;cell death#GO:0008219;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;anatomical structure development#GO:0048856;localization#GO:0051179;macromolecule localization#GO:0033036;lipid transport#GO:0006869;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;phagocytosis#GO:0006909;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;cellular component organization#GO:0016043;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;endocytosis#GO:0006897;lipid localization#GO:0010876;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;cellular process#GO:0009987;endomembrane system organization#GO:0010256;membrane invagination#GO:0010324;import into cell#GO:0098657;apoptotic cell clearance#GO:0043277;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000005572.4|UniProtKB=A0A5F8GIU0 A0A5F8GIU0 ZMYND11 PTHR46379:SF1 ZINC FINGER MYND DOMAIN-CONTAINING ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 11 histone reader activity#GO:0140566;histone H3 reader activity#GO:0140006;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463 RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;chromatin remodeling#GO:0006338;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;chromatin organization#GO:0006325;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000009896.3|UniProtKB=F6VC86 F6VC86 ATP6V1D PTHR11671:SF5 V-TYPE ATP SYNTHASE SUBUNIT D V-TYPE PROTON ATPASE SUBUNIT D ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075 biological regulation#GO:0065007;homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;intracellular chemical homeostasis#GO:0055082;vacuolar acidification#GO:0007035;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885 protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting two-sector ATPase complex#GO:0016469;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000015402.4|UniProtKB=F7G1F5 F7G1F5 SPRING1 PTHR13481:SF0 SREBP REGULATING GENE PROTEIN SREBP REGULATING GENE PROTEIN MONDO|Ensembl=ENSMODG00000005078.4|UniProtKB=F7A4M5 F7A4M5 PAK1 PTHR48015:SF20 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE PAK 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of axonogenesis#GO:0050770;regulation of anatomical structure morphogenesis#GO:0022603;regulation of MAPK cascade#GO:0043408;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell migration#GO:0016477;response to nutrient levels#GO:0031667;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;cellular response to starvation#GO:0009267;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Axon guidance mediated by semaphorins#P00007>PAK#P00331;CCKR signaling map#P06959>PAK1#P07065;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517;Angiogenesis#P00005>PAK#P00249;T cell activation#P00053>PAK#P01319;Ras Pathway#P04393>PAK#P04553;CCKR signaling map#P06959>PAK#P07091;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837 MONDO|Ensembl=ENSMODG00000013592.4|UniProtKB=F6VVX3 F6VVX3 HHATL PTHR13285:SF19 ACYLTRANSFERASE PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE HHAT-LIKE PROTEIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of protein modification process#GO:0031399 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000029122.1|UniProtKB=K7E698 K7E698 CIMIP2B PTHR22146:SF8 CAT EYE SYNDROME CRITICAL REGION PROTEIN 6 CILIARY MICROTUBULE INNER PROTEIN 2B MONDO|Ensembl=ENSMODG00000009196.3|UniProtKB=F6ZMS3 F6ZMS3 PTHR26453:SF631 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000047520.1|UniProtKB=A0A5F8GWT7 A0A5F8GWT7 PTHR48001:SF24 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027605.1|UniProtKB=K7E3V4 K7E3V4 LRRC72 PTHR46759:SF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 72 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 72 MONDO|Ensembl=ENSMODG00000001307.4|UniProtKB=A0A5F8H8T1 A0A5F8H8T1 EFR3A PTHR12444:SF1 PROTEIN EFR3 HOMOLOG CMP44E PROTEIN EFR3 HOMOLOG A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000004716.4|UniProtKB=F6QGH4 F6QGH4 ATP13A1 PTHR45630:SF20 CATION-TRANSPORTING ATPASE-RELATED ENDOPLASMIC RETICULUM TRANSMEMBRANE HELIX TRANSLOCASE protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104;ATP-dependent activity#GO:0140657 calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;localization within membrane#GO:0051668;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000008568.4|UniProtKB=A0A5F8G476 A0A5F8G476 IDH3G PTHR11835:SF60 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000014888.3|UniProtKB=F7GGI0 F7GGI0 RAB8A PTHR47980:SF33 LD44762P RAS-RELATED PROTEIN RAB-8A localization within membrane#GO:0051668;organelle assembly#GO:0070925;protein localization to cell junction#GO:1902414;localization#GO:0051179;secretion#GO:0046903;macromolecule localization#GO:0033036;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular transport#GO:0046907;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;cilium assembly#GO:0060271;export from cell#GO:0140352;endocytic recycling#GO:0032456;cell projection organization#GO:0030030;secretion by cell#GO:0032940;cilium organization#GO:0044782;regulation of biological quality#GO:0065008;protein transport#GO:0015031;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;protein localization to cell periphery#GO:1990778;exocytosis#GO:0006887;endosomal transport#GO:0016197;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;protein localization to synapse#GO:0035418;cellular component organization or biogenesis#GO:0071840 plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;trans-Golgi network transport vesicle#GO:0030140 Huntington disease#P00029>Rab8#P00783 MONDO|Ensembl=ENSMODG00000009522.4|UniProtKB=F7EV06 F7EV06 IGFBP3 PTHR11551:SF3 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 3 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 p53 pathway#P00059>IGF-BP3#G04691 MONDO|Ensembl=ENSMODG00000016023.3|UniProtKB=F7EFX7 F7EFX7 POLR1H PTHR11239:SF14 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12 catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription termination#GO:0006353;transcription by RNA polymerase I#GO:0006360;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;RNA polymerase I complex#GO:0005736;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974 DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000014667.4|UniProtKB=F7E818 F7E818 MBOAT2 PTHR13906:SF7 PORCUPINE MEMBRANE-BOUND GLYCEROPHOSPHOLIPID O-ACYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;lipid modification#GO:0030258;cellular process#GO:0009987;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650 membrane#GO:0016020;cellular anatomical structure#GO:0110165 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000006778.4|UniProtKB=F6PH74 F6PH74 ERICH5 PTHR23006:SF0 GLUTAMATE-RICH PROTEIN 5 GLUTAMATE-RICH PROTEIN 5 MONDO|Ensembl=ENSMODG00000023281.2|UniProtKB=F6SDY7 F6SDY7 RNF208 PTHR22791:SF3 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF182-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000003648.2|UniProtKB=A0A5F8G7B8 A0A5F8G7B8 PTHR10797:SF79 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 7 exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;RNA nuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098 regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779 CCR4-NOT complex#GO:0030014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031;RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000021428.4|UniProtKB=F7CBD6 F7CBD6 AFG3L2 PTHR43655:SF9 ATP-DEPENDENT PROTEASE MITOCHONDRIAL INNER MEMBRANE M-AAA PROTEASE COMPONENT AFG3L2 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000038996.1|UniProtKB=A0A5F8HJD1 A0A5F8HJD1 CIMIP1 PTHR31909:SF3 CHROMOSOME 20 ORF85 FAMILY MEMBER CILIARY MICROTUBULE INNER PROTEIN 1 MONDO|Ensembl=ENSMODG00000042445.1|UniProtKB=A0A5F8GJQ4 A0A5F8GJQ4 PTHR24379:SF131 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 712 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000012247.4|UniProtKB=A0A5F8GTD7 A0A5F8GTD7 FAM13B PTHR15904:SF16 FAM13 PROTEIN FAM13B MONDO|Ensembl=ENSMODG00000011749.4|UniProtKB=A0A5F8GBU5 A0A5F8GBU5 CACNA1A PTHR45628:SF3 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT P_Q-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1A monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836 monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;synaptic signaling#GO:0099536;inorganic cation import across plasma membrane#GO:0098659;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;inorganic ion import across plasma membrane#GO:0099587;signaling#GO:0023052;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;anterograde trans-synaptic signaling#GO:0098916;calcium ion import#GO:0070509;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;calcium ion transmembrane transport#GO:0070588;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;trans-synaptic signaling#GO:0099537 cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;calcium channel complex#GO:0034704;cell body#GO:0044297;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transporter complex#GO:1990351;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241 Endogenous cannabinoid signaling#P05730>Ca2+ channel#P05750;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ca2+channel#P00742;Ionotropic glutamate receptor pathway#P00037>Ca2+ channel#P01022;GABA-B receptor II signaling#P05731>Ca channel#P05753;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051 MONDO|Ensembl=ENSMODG00000011051.3|UniProtKB=F7EMZ0 F7EMZ0 DUSP26 PTHR45682:SF8 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE 26 phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000046164.1|UniProtKB=A0A5F8GAN4 A0A5F8GAN4 PTHR11346:SF97 GALECTIN GALECTIN-1 carbohydrate binding#GO:0030246;extracellular matrix binding#GO:0050840;protein binding#GO:0005515;binding#GO:0005488;oligosaccharide binding#GO:0070492;laminin binding#GO:0043236 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000006591.4|UniProtKB=A0A5F8HD28 A0A5F8HD28 PITRM1 PTHR43016:SF18 PRESEQUENCE PROTEASE PRESEQUENCE PROTEASE, MITOCHONDRIAL catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000016577.3|UniProtKB=H9H700 H9H700 DESI1 PTHR12378:SF7 DESUMOYLATING ISOPEPTIDASE DESUMOYLATING ISOPEPTIDASE 1 cellular localization#GO:0051641;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;localization#GO:0051179;regulation of protein catabolic process#GO:0042176;nuclear export#GO:0051168;protein transport#GO:0015031;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of catabolic process#GO:0009894;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;intracellular protein transport#GO:0006886;transport#GO:0006810;regulation of proteasomal protein catabolic process#GO:0061136;biological regulation#GO:0065007;protein export from nucleus#GO:0006611;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000003584.5|UniProtKB=F7FPY2 F7FPY2 FBXO8 PTHR10663:SF372 GUANYL-NUCLEOTIDE EXCHANGE FACTOR F-BOX ONLY PROTEIN 8 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000007947.4|UniProtKB=F7G8U6 F7G8U6 TTC9C PTHR11242:SF14 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 9C protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;membrane#GO:0016020 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000000172.2|UniProtKB=F6X9Y8 F6X9Y8 UCP1 PTHR45618:SF19 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL BROWN FAT UNCOUPLING PROTEIN 1 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;response to abiotic stimulus#GO:0009628;homeostatic process#GO:0042592;mitochondrial transport#GO:0006839;response to stimulus#GO:0050896;response to cold#GO:0009409;adaptive thermogenesis#GO:1990845;mitochondrial transmembrane transport#GO:1990542;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;response to stress#GO:0006950;biological regulation#GO:0065007;response to temperature stimulus#GO:0009266;regulation of multicellular organismal process#GO:0051239;multicellular organismal process#GO:0032501;transport#GO:0006810;temperature homeostasis#GO:0001659;intracellular transport#GO:0046907;multicellular organismal-level homeostasis#GO:0048871;establishment of localization#GO:0051234 mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000020313.4|UniProtKB=F7G7N5 F7G7N5 FYB1 PTHR16830:SF13 SH2 CONTAINING ADAPTOR PRAM-1 RELATED FYN-BINDING PROTEIN 1 intracellular protein localization#GO:0008104;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;macromolecule localization#GO:0033036;cell communication#GO:0007154;localization#GO:0051179;localization within membrane#GO:0051668;regulation of immune response#GO:0050776;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;protein localization to plasma membrane#GO:0072659;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;protein localization to cell periphery#GO:1990778;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;cellular localization#GO:0051641;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;protein localization to membrane#GO:0072657;integrin-mediated signaling pathway#GO:0007229 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019635.4|UniProtKB=F6XPI2 F6XPI2 PSMD5 PTHR13554:SF10 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5 protease#PC00190 MONDO|Ensembl=ENSMODG00000027995.2|UniProtKB=A0A5F8GFS9 A0A5F8GFS9 PTHR44533:SF5 DEAD/H RNA HELICASE, PUTATIVE-RELATED DEXD_H-BOX HELICASE 60 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000014653.4|UniProtKB=F7EQ19 F7EQ19 ACAT1 PTHR18919:SF156 ACETYL-COA C-ACYLTRANSFERASE ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;sterol metabolic process#GO:0016125;steroid metabolic process#GO:0008202 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 acyltransferase#PC00042;transferase#PC00220 CCKR signaling map#P06959>ACAT1#G06992;CCKR signaling map#P06959>ACAT1#G07285 MONDO|Ensembl=ENSMODG00000016729.3|UniProtKB=A0A5F8HHQ2 A0A5F8HHQ2 PTHR10709:SF11 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 1A cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cortical actin cytoskeleton organization#GO:0030866;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885 actin or actin-binding cytoskeletal protein#PC00041 Huntington disease#P00029>Arp2/3 complex#P00811;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 MONDO|Ensembl=ENSMODG00000045972.1|UniProtKB=F7EID0 F7EID0 PTHR48018:SF106 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M11 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013858.3|UniProtKB=F6X5H0 F6X5H0 PTHR47078:SF1 CYTOSKELETON-ASSOCIATED PROTEIN 2-LIKE CYTOSKELETON-ASSOCIATED PROTEIN 2-LIKE spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;mitotic spindle#GO:0072686 MONDO|Ensembl=ENSMODG00000024795.2|UniProtKB=F6RHZ7 F6RHZ7 LOC103098704 PTHR10880:SF48 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000002704.2|UniProtKB=F7CY16 F7CY16 CAPN10 PTHR10183:SF30 CALPAIN CALPAIN-10 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 MONDO|Ensembl=ENSMODG00000013217.3|UniProtKB=A0A5F8GU21 A0A5F8GU21 RNF26 PTHR22696:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF26 E3 UBIQUITIN-PROTEIN LIGASE RNF26 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000009457.4|UniProtKB=F7BG84 F7BG84 MTHFD1 PTHR48099:SF1 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;oxidoreductase activity#GO:0016491;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824 folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;tetrahydrofolate metabolic process#GO:0046653;metabolic process#GO:0008152;tetrahydrofolate biosynthetic process#GO:0046654 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000004120.3|UniProtKB=F6UWP1 F6UWP1 LOC100018242 PTHR11927:SF9 GALACTOSIDE 2-L-FUCOSYLTRANSFERASE L-FUCOSYLTRANSFERASE fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000042574.1|UniProtKB=A0A5F8H5F6 A0A5F8H5F6 PTHR24390:SF79 ZINC FINGER PROTEIN LD33778P sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000001169.3|UniProtKB=F7GHF9 F7GHF9 FOXN2 PTHR13962:SF19 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N2 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000013668.4|UniProtKB=F6TXC8 F6TXC8 PTHR21029:SF5 R-SEVEN BINDING PROTEIN (R7BP) HOMOLOG REGULATOR OF G-PROTEIN SIGNALING 9-BINDING PROTEIN cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 neuron projection#GO:0043005;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000014691.4|UniProtKB=F7DN51 F7DN51 ITGB1BP1 PTHR32055:SF1 INTEGRIN BETA-1-BINDING PROTEIN 1 INTEGRIN BETA-1-BINDING PROTEIN 1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;signaling receptor binding#GO:0005102;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 regulation of cellular component organization#GO:0051128;negative regulation of cell adhesion#GO:0007162;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;regulation of biological process#GO:0050789;regulation of cell-matrix adhesion#GO:0001952;negative regulation of cellular process#GO:0048523;regulation of cell junction assembly#GO:1901888 cell leading edge#GO:0031252;cell periphery#GO:0071944;organelle#GO:0043226;lamellipodium#GO:0030027;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;ruffle#GO:0001726;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000001046.4|UniProtKB=F6YRV9 F6YRV9 GPNMB PTHR11861:SF11 MELANOCYTE PROTEIN PMEL 17-RELATED TRANSMEMBRANE GLYCOPROTEIN NMB protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;binding#GO:0005488;signaling receptor binding#GO:0005102;cell adhesion molecule binding#GO:0050839 cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000017354.4|UniProtKB=F6VZW0 F6VZW0 INTS3 PTHR13587:SF7 INTEGRATOR COMPLEX SUBUNIT 3 INTEGRATOR COMPLEX SUBUNIT 3 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000003330.4|UniProtKB=A0A5F8G5U2 A0A5F8G5U2 PTPN3 PTHR45706:SF5 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 3 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000029016.1|UniProtKB=K7E0P1 K7E0P1 PTHR10424:SF72 VIRAL ENVELOPE PROTEIN BC035947 PROTEIN-RELATED striated muscle cell differentiation#GO:0051146;syncytium formation by cell-cell fusion#GO:0000768;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;developmental process#GO:0032502;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;myoblast fusion#GO:0007520 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000004606.3|UniProtKB=F6Y4D4 F6Y4D4 PTHR48112:SF12 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP BOX 1, PSEUDOGENE 34 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 p53 pathway#P00059>HMG1#P04619 MONDO|Ensembl=ENSMODG00000004646.2|UniProtKB=F6UNB8 F6UNB8 PTHR22883:SF49 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC7 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;protein targeting to membrane#GO:0006612;protein localization to cell periphery#GO:1990778;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;regulation of signaling#GO:0023051;regulation of cell communication#GO:0010646;protein targeting#GO:0006605;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000013570.4|UniProtKB=A0A5F8GJB9 A0A5F8GJB9 SUPT5H PTHR11125:SF7 SUPPRESSOR OF TY 5 TRANSCRIPTION ELONGATION FACTOR SPT5 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;DNA-templated transcription elongation#GO:0006354;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000046786.1|UniProtKB=A0A5F8GDP1 A0A5F8GDP1 KITLG PTHR11574:SF0 KIT LIGAND KIT LIGAND positive regulation of cell population proliferation#GO:0008284;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000009096.4|UniProtKB=F7FQL3 F7FQL3 IRAK3 PTHR24419:SF7 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 3 phosphotransferase activity, alcohol group as acceptor#GO:0016773;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;positive regulation of signal transduction#GO:0009967;cell cycle#GO:0007049;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;response to bacterium#GO:0009617;lipopolysaccharide-mediated signaling pathway#GO:0031663;cytokine-mediated signaling pathway#GO:0019221;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;response to cytokine#GO:0034097;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;response to molecule of bacterial origin#GO:0002237;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>IRAKM#P01378 MONDO|Ensembl=ENSMODG00000010139.3|UniProtKB=F6W894 F6W894 PTHR28052:SF1 UPF0545 PROTEIN C22ORF39 SYNAPTIC PLASTICITY REGULATOR PANTS MONDO|Ensembl=ENSMODG00000002311.4|UniProtKB=A0A5F8GMQ2 A0A5F8GMQ2 STXBP3 PTHR11679:SF33 VESICLE PROTEIN SORTING-ASSOCIATED SYNTAXIN-BINDING PROTEIN 3 SNARE binding#GO:0000149;binding#GO:0005488;protein binding#GO:0005515;syntaxin binding#GO:0019905 trans-synaptic signaling#GO:0099537;organelle localization#GO:0051640;signal release#GO:0023061;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;intracellular transport#GO:0046907;calcium-ion regulated exocytosis#GO:0017156;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;vesicle localization#GO:0051648;macromolecule localization#GO:0033036;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;protein transport#GO:0015031;secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of biological process#GO:0050789;export from cell#GO:0140352;signaling#GO:0023052;establishment of organelle localization#GO:0051656;intracellular protein transport#GO:0006886;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;cellular process#GO:0009987;establishment of protein localization#GO:0045184;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;neurotransmitter transport#GO:0006836;establishment of vesicle localization#GO:0051650;vesicle-mediated transport#GO:0016192 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000013167.4|UniProtKB=F6ZM79 F6ZM79 RBL2 PTHR13742:SF8 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RETINOBLASTOMA-LIKE PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;developmental process#GO:0032502;cellular developmental process#GO:0048869;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000015060.4|UniProtKB=F7FHP5 F7FHP5 TP63 PTHR11447:SF8 CELLULAR TUMOR ANTIGEN P53 TUMOR PROTEIN 63 transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell death#GO:0008219;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;apoptotic signaling pathway#GO:0097190;regulation of biosynthetic process#GO:0009889;DNA damage response#GO:0006974;signaling#GO:0023052;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;regulation of programmed cell death#GO:0043067;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;signal transduction by p53 class mediator#GO:0072331;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;regulation of apoptotic process#GO:0042981;positive regulation of transcription by RNA polymerase II#GO:0045944 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 P53-like transcription factor#PC00253;gene-specific transcriptional regulator#PC00264 Huntington disease#P00029>p53#P00797;p53 pathway#P00059>p53#P01485;p53 pathway feedback loops 2#P04398>p53#P04668;P53 pathway feedback loops 1#P04392>p73DeltaN#G04685;P53 pathway feedback loops 1#P04392>p73DeltaN#P04537;p53 pathway#P00059>p53#G04702;P53 pathway feedback loops 1#P04392>p53#P04539;p53 pathway by glucose deprivation#P04397>p53#P04640 MONDO|Ensembl=ENSMODG00000011599.4|UniProtKB=A0A5F8GQK1 A0A5F8GQK1 GPLD1 PTHR23221:SF7 GLYCOSYLPHOSPHATIDYLINOSITOL PHOSPHOLIPASE D PHOSPHATIDYLINOSITOL-GLYCAN-SPECIFIC PHOSPHOLIPASE D phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;lipase activity#GO:0016298 protein localization to extracellular region#GO:0071692;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;localization#GO:0051179;enzyme-linked receptor protein signaling pathway#GO:0007167;secretion#GO:0046903;macromolecule localization#GO:0033036;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;cellular response to nitrogen compound#GO:1901699;cellular response to insulin stimulus#GO:0032869;transport#GO:0006810;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;export from cell#GO:0140352;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;secretion by cell#GO:0032940;protein transport#GO:0015031;protein secretion#GO:0009306;cellular response to oxygen-containing compound#GO:1901701;establishment of protein localization#GO:0045184;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLD#P06839 MONDO|Ensembl=ENSMODG00000013259.4|UniProtKB=F7D9Z3 F7D9Z3 PPP2R5C PTHR10257:SF123 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM phosphatase activator activity#GO:0019211;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;enzyme activator activity#GO:0008047 meiotic sister chromatid cohesion#GO:0051177;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;protein phosphatase#PC00195 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 MONDO|Ensembl=ENSMODG00000038997.1|UniProtKB=K7E6B7 K7E6B7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000041630.1|UniProtKB=A0A5F8HD89 A0A5F8HD89 EFCAB2 PTHR46763:SF1 DYNEIN REGULATORY COMPLEX PROTEIN 8 DYNEIN REGULATORY COMPLEX PROTEIN 8 membrane-bounded organelle#GO:0043227;9+2 motile cilium#GO:0097729;cilium#GO:0005929;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;sperm principal piece#GO:0097228 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000049018.1|UniProtKB=A0A5F8HCJ0 A0A5F8HCJ0 FADS6 PTHR19353:SF13 FATTY ACID DESATURASE 2 FATTY ACID DESATURASE 6 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000011967.4|UniProtKB=F7CUV6 F7CUV6 ETFA PTHR43153:SF1 ELECTRON TRANSFER FLAVOPROTEIN ALPHA ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid modification#GO:0030258;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000011671.3|UniProtKB=F7GEG0 F7GEG0 C6orf62 PTHR28336:SF1 BA1-643 SIMILAR TO CDNA SEQUENCE BC005537 MONDO|Ensembl=ENSMODG00000025657.3|UniProtKB=F6XDS3 F6XDS3 PTHR24091:SF0 LYMPHOCYTE TRANSMEMBRANE ADAPTER 1 LYMPHOCYTE TRANSMEMBRANE ADAPTER 1 regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;regulation of T cell activation#GO:0050863;lymphocyte activation#GO:0046649;antigen receptor-mediated signaling pathway#GO:0050851;negative regulation of cell-cell adhesion#GO:0022408;cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;immune system process#GO:0002376;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;immune response-regulating cell surface receptor signaling pathway#GO:0002768;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;negative regulation of cell activation#GO:0050866;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;immune response-activating cell surface receptor signaling pathway#GO:0002429;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;negative regulation of multicellular organismal process#GO:0051241;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cell activation#GO:0001775;negative regulation of T cell activation#GO:0050868;regulation of immune response#GO:0050776 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000006850.4|UniProtKB=F6PFR9 F6PFR9 RGS16 PTHR10845:SF187 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 16 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 MONDO|Ensembl=ENSMODG00000012419.3|UniProtKB=F6PMB7 F6PMB7 KCTD18 PTHR14499:SF4 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD18 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020368.4|UniProtKB=A0A5F8GL87 A0A5F8GL87 PTHR34349:SF1 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 32 STABILIZER OF AXONEMAL MICROTUBULES 4 protein binding#GO:0005515;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899 phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000045857.1|UniProtKB=A0A5F8H7S9 A0A5F8H7S9 PTHR26452:SF310 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016199.2|UniProtKB=A0A5F8GYJ4 A0A5F8GYJ4 UBE2I PTHR24067:SF311 UBIQUITIN-CONJUGATING ENZYME E2 SUMO-CONJUGATING ENZYME UBC9-B SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein sumoylation#GO:0016925;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;post-translational protein modification#GO:0043687 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000017640.3|UniProtKB=F6Z4H7 F6Z4H7 GATM PTHR10488:SF1 GLYCINE AMIDINOTRANSFERASE, MITOCHONDRIAL GLYCINE AMIDINOTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;monocarboxylic acid metabolic process#GO:0032787;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000004171.4|UniProtKB=F6QPG3 F6QPG3 WWC2 PTHR14791:SF26 BOMB/KIRA PROTEINS PROTEIN WWC2 enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;protein binding#GO:0005515 regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell migration#GO:0016477;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of macromolecule metabolic process#GO:0060255;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of growth#GO:0040008;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000003370.4|UniProtKB=F6ZPK7 F6ZPK7 DPH5 PTHR10882:SF0 DIPHTHINE SYNTHASE DIPHTHINE METHYL ESTER SYNTHASE methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000015865.3|UniProtKB=F7F085 F7F085 FLOT1 PTHR13806:SF47 FLOTILLIN-RELATED FLOTILLIN-1 positive regulation of endocytosis#GO:0045807;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of vesicle-mediated transport#GO:0060627;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of endocytosis#GO:0030100;positive regulation of cellular component organization#GO:0051130 cell periphery#GO:0071944;caveola#GO:0005901;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;membrane microdomain#GO:0098857;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;membrane raft#GO:0045121;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane raft#GO:0044853 MONDO|Ensembl=ENSMODG00000016578.4|UniProtKB=F7D3D3 F7D3D3 LOC100618901 PTHR24256:SF574 TRYPTASE-RELATED INACTIVE SERINE PROTEASE 39-RELATED serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000008886.4|UniProtKB=F7BS20 F7BS20 MYO1E PTHR13140:SF341 MYOSIN UNCONVENTIONAL MYOSIN-IE ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;transport#GO:0006810;actin filament-based process#GO:0030029;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;microvillus#GO:0005902;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000023275.2|UniProtKB=F6SWW7 F6SWW7 PTHR11334:SF60 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G-PROTEIN COUPLED RECEPTOR MEMBER H G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028241.2|UniProtKB=K7E4L4 K7E4L4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000005044.4|UniProtKB=A0A5F8HH88 A0A5F8HH88 TASP1 PTHR10188:SF8 L-ASPARAGINASE THREONINE ASPARTASE 1 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000012394.4|UniProtKB=F6PN80 F6PN80 UBA7 PTHR10953:SF143 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 7 catalytic activity, acting on a protein#GO:0140096;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;ligase activity#GO:0016874;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;protein ubiquitination#GO:0016567;defense response to other organism#GO:0098542;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;immune system process#GO:0002376;protein modification by small protein conjugation#GO:0032446;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;DNA damage response#GO:0006974;response to external stimulus#GO:0009605;ubiquitin-dependent protein catabolic process#GO:0006511;defense response#GO:0006952;macromolecule metabolic process#GO:0043170;innate immune response#GO:0045087;immune response#GO:0006955;response to other organism#GO:0051707;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;protein modification process#GO:0036211;primary metabolic process#GO:0044238;response to external biotic stimulus#GO:0043207;ISG15-protein conjugation#GO:0032020;catabolic process#GO:0009056 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492;Ubiquitin proteasome pathway#P00060>E3#P01490 MONDO|Ensembl=ENSMODG00000040208.1|UniProtKB=A0A5F8HHJ2 A0A5F8HHJ2 PTHR46916:SF1 TRANSMEMBRANE PROTEIN 205 SI:CH211-121A2.4 MONDO|Ensembl=ENSMODG00000023937.1|UniProtKB=F7F889 F7F889 KCNJ16 PTHR11767:SF24 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 16 transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;transport#GO:0006810;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000001129.3|UniProtKB=F7D515 F7D515 MSH6 PTHR11361:SF148 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH6 ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;catalytic activity, acting on DNA#GO:0140097 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;mismatch repair#GO:0006298;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000039359.1|UniProtKB=A0A5F8HEB6 A0A5F8HEB6 PTHR12484:SF1 B-LYMPHOCYTE ANTIGEN-RELATED A-KINASE ANCHOR PROTEIN 17B MONDO|Ensembl=ENSMODG00000003612.4|UniProtKB=F6QK70 F6QK70 CASP9 PTHR10454:SF157 CASPASE CASPASE-9 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;positive regulation of apoptotic process#GO:0043065;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;regulation of apoptotic process#GO:0042981;positive regulation of neuron apoptotic process#GO:0043525 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein modifying enzyme#PC00260;protease#PC00190 PI3 kinase pathway#P00048>Caspase-9#P01197;FAS signaling pathway#P00020>Pro-Caspase9#P00603;VEGF signaling pathway#P00056>Caspase9#P01410;FAS signaling pathway#P00020>Caspase9#P00593;Angiogenesis#P00005>Caspase 9#P00216;Apoptosis signaling pathway#P00006>Caspase 9#P00298 MONDO|Ensembl=ENSMODG00000002591.4|UniProtKB=A0A5F8HBJ6 A0A5F8HBJ6 TMC1 PTHR23302:SF18 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 1 channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215 system process#GO:0003008;response to external stimulus#GO:0009605;nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;detection of mechanical stimulus#GO:0050982;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;sensory perception of sound#GO:0007605;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000010433.4|UniProtKB=F6YTJ2 F6YTJ2 RNF14 PTHR11685:SF371 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF14 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;acyltransferase activity#GO:0016746;binding#GO:0005488;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000018456.4|UniProtKB=F7CU62 F7CU62 BCL2L13 PTHR15758:SF2 BCL-2-LIKE PROTEIN 13 BCL-2-LIKE PROTEIN 13 MONDO|Ensembl=ENSMODG00000029716.2|UniProtKB=K7E1Q6 K7E1Q6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009489.4|UniProtKB=F7DYC7 F7DYC7 RMND5A PTHR12170:SF5 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED E3 UBIQUITIN-PROTEIN TRANSFERASE RMND5A ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000012062.3|UniProtKB=F7G556 F7G556 RGS1 PTHR10845:SF34 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 1 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 MONDO|Ensembl=ENSMODG00000020729.4|UniProtKB=F7ANS0 F7ANS0 PTHR16510:SF4 EXTRACELLULAR MATRIX PHOSPHOGLYCOPROTEIN WITH ASARM MOTIF MATRIX EXTRACELLULAR PHOSPHOGLYCOPROTEIN protein binding#GO:0005515;binding#GO:0005488 biomineral tissue development#GO:0031214;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;tissue development#GO:0009888;anatomical structure development#GO:0048856;animal organ development#GO:0048513 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000006537.4|UniProtKB=A0A5F8HK98 A0A5F8HK98 SCN1A PTHR10037:SF280 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 1 SUBUNIT ALPHA transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;voltage-gated sodium channel activity#GO:0005248;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 metal ion transport#GO:0030001;membrane depolarization#GO:0051899;sodium ion transport#GO:0006814;action potential#GO:0001508;sensory perception of pain#GO:0019233;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;nervous system process#GO:0050877;sensory perception#GO:0007600;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;multicellular organismal process#GO:0032501;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;transmission of nerve impulse#GO:0019226;system process#GO:0003008;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810 plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;axon#GO:0030424;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;transporter complex#GO:1990351 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000008213.3|UniProtKB=F6ZYJ0 F6ZYJ0 MFSD6L PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000001699.4|UniProtKB=A0A5F8H3N7 A0A5F8H3N7 CTF1 PTHR21353:SF2 FAMILY NOT NAMED CARDIOTROPHIN-1 cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cell surface receptor signaling pathway#GO:0007166;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;cell surface receptor signaling pathway via STAT#GO:0097696;nervous system development#GO:0007399;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000014312.3|UniProtKB=F6W4B4 F6W4B4 PTHR10206:SF2 CATHELICIDIN CATHELICIDIN ANTIMICROBIAL PEPTIDE lipid binding#GO:0008289;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;lipopolysaccharide binding#GO:0001530 defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;response to stimulus#GO:0050896;defense response to Gram-negative bacterium#GO:0050829;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to Gram-positive bacterium#GO:0050830;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051 MONDO|Ensembl=ENSMODG00000051049.1|UniProtKB=A0A5F8GPW6 A0A5F8GPW6 LOC103103205 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008615.4|UniProtKB=A0A5F8GDZ6 A0A5F8GDZ6 PPM1A PTHR47992:SF121 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1A protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein phosphatase#PC00195;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000042003.1|UniProtKB=A0A5F8HBE4 A0A5F8HBE4 LOC100010708 PTHR26453:SF156 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048268.1|UniProtKB=A0A5F8H9I7 A0A5F8H9I7 AIFM3 PTHR43557:SF8 APOPTOSIS-INDUCING FACTOR 1 APOPTOSIS-INDUCING FACTOR 3 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824 apoptotic process#GO:0006915;cellular process#GO:0009987;cell death#GO:0008219;execution phase of apoptosis#GO:0097194;programmed cell death#GO:0012501 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000025240.1|UniProtKB=F7A7I3 F7A7I3 LOC100029767 PTHR11937:SF208 ACTIN ACTIN-LIKE PROTEIN 8 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039 Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807 MONDO|Ensembl=ENSMODG00000002268.4|UniProtKB=F7CVY1 F7CVY1 GPSM2 PTHR45954:SF3 LD33695P G PROTEIN-SIGNALING MODULATOR 2 binding#GO:0005488;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cell cycle process#GO:0022402;establishment of cell polarity#GO:0030010;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;establishment of organelle localization#GO:0051656;mitotic cell cycle#GO:0000278;organelle localization#GO:0051640;establishment or maintenance of cell polarity#GO:0007163;spindle localization#GO:0051653;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of spindle localization#GO:0051293;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;mitotic cell cycle process#GO:1903047;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;cellular component organization or biogenesis#GO:0071840 cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>AGS3#P00715;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>AGS3#P00739 MONDO|Ensembl=ENSMODG00000028683.2|UniProtKB=K7E0M7 K7E0M7 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000899.3|UniProtKB=F7A744 F7A744 PTHR24264:SF15 TRYPSIN-RELATED TRYPSIN catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000023793.2|UniProtKB=F6VTL2 F6VTL2 LOC100009916 PTHR11927:SF9 GALACTOSIDE 2-L-FUCOSYLTRANSFERASE L-FUCOSYLTRANSFERASE fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000000629.4|UniProtKB=F6TAN2 F6TAN2 GPR176 PTHR22752:SF1 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 176 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000978.3|UniProtKB=F7ESE7 F7ESE7 PTHR31606:SF4 WW DOMAIN BINDING PROTEIN 2, ISOFORM E WW DOMAIN-BINDING PROTEIN 2 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;chromatin DNA binding#GO:0031490;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000023186.2|UniProtKB=F7C4T7 F7C4T7 LOC100021551 PTHR24103:SF676 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000020794.4|UniProtKB=A0A5F8HLH9 A0A5F8HLH9 ANTXR2 PTHR16059:SF13 ANTHRAX TOXIN RECEPTOR ANTHRAX TOXIN RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000024796.2|UniProtKB=F7FPL9 F7FPL9 LOC100018100 PTHR10263:SF5 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 16 KDA PROTEOLIPID SUBUNIT C cellular anatomical structure#GO:0110165;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000046633.1|UniProtKB=A0A5F8GX31 A0A5F8GX31 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000023387.2|UniProtKB=F6TQH8 F6TQH8 PTHR28342:SF1 MONOOXYGENASE P33MONOX-RELATED MONOOXYGENASE P33MONOX-RELATED intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000013041.4|UniProtKB=F7GBG6 F7GBG6 TBCEL PTHR15140:SF69 TUBULIN-SPECIFIC CHAPERONE E TUBULIN-SPECIFIC CHAPERONE COFACTOR E-LIKE PROTEIN protein binding#GO:0005515;binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000015079.4|UniProtKB=F6TKB8 F6TKB8 AOC2 PTHR10638:SF4 COPPER AMINE OXIDASE AMINE OXIDASE [COPPER-CONTAINING] 2 copper ion binding#GO:0005507;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 cellular process#GO:0009987;metabolic process#GO:0008152;amine metabolic process#GO:0009308 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 oxidoreductase#PC00176;oxidase#PC00175 Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103 MONDO|Ensembl=ENSMODG00000007803.4|UniProtKB=F6ZIM5 F6ZIM5 ARAP1 PTHR45899:SF3 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;lipid binding#GO:0008289;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047;phospholipid binding#GO:0005543;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;phosphatidylinositol phosphate binding#GO:1901981 regulation of cell projection organization#GO:0031344;regulation of actin filament-based process#GO:0032970;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000001435.4|UniProtKB=A0A5F8HEI4 A0A5F8HEI4 USP22 PTHR21646:SF112 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 22 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of protein stability#GO:0031647;regulation of DNA-templated transcription#GO:0006355;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000040826.1|UniProtKB=A0A5F8GCG2 A0A5F8GCG2 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000000544.4|UniProtKB=F6XN43 F6XN43 CDC14B PTHR23339:SF74 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE CDC14B hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;regulation of cell cycle#GO:0051726;cilium assembly#GO:0060271;cellular component organization#GO:0016043;regulation of cell cycle phase transition#GO:1901987;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;microtubule cytoskeleton organization#GO:0000226;regulation of mitotic cell cycle phase transition#GO:1901990;cilium organization#GO:0044782;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;positive regulation of cell cycle#GO:0045787;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;cell projection assembly#GO:0030031;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031 mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000000547.2|UniProtKB=F6XM34 F6XM34 PTHR45828:SF51 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE REELIN DOMAIN-CONTAINING PROTEIN 1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000000669.3|UniProtKB=F6X261 F6X261 MMP27 PTHR10201:SF115 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-27 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;metabolic process#GO:0008152;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 MONDO|Ensembl=ENSMODG00000037420.1|UniProtKB=A0A5F8HLA8 A0A5F8HLA8 PTHR26450:SF424 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56A4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010799.3|UniProtKB=A0A5F8H1H7 A0A5F8H1H7 PTHR20951:SF2 C13ORF1 PROTEIN-RELATED SPRY DOMAIN-CONTAINING PROTEIN 7 MONDO|Ensembl=ENSMODG00000002494.3|UniProtKB=F7BVM7 F7BVM7 LOC100028657 PTHR24255:SF27 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED HAPTOGLOBIN-RELATED PROTEIN serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;zymogen activation#GO:0031638;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000042176.1|UniProtKB=A0A5F8HDQ0 A0A5F8HDQ0 PTHR26450:SF422 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019929.3|UniProtKB=F6V845 F6V845 LOC100018060 PTHR48002:SF146 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4X2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000051335.1|UniProtKB=A0A5F8H1K3 A0A5F8H1K3 FRS2 PTHR21258:SF40 DOCKING PROTEIN RELATED FIBROBLAST GROWTH FACTOR RECEPTOR SUBSTRATE 2 signaling adaptor activity#GO:0035591;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;binding#GO:0005488;kinase binding#GO:0019900;protein-macromolecule adaptor activity#GO:0030674;fibroblast growth factor receptor binding#GO:0005104;receptor tyrosine kinase binding#GO:0030971;signaling receptor complex adaptor activity#GO:0030159;growth factor receptor binding#GO:0070851;molecular adaptor activity#GO:0060090 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;signal transduction#GO:0007165;biological regulation#GO:0065007;fibroblast growth factor receptor signaling pathway#GO:0008543;cell surface receptor signaling pathway#GO:0007166;response to fibroblast growth factor#GO:0071774 anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell-cell junction#GO:0005911 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>FRS-2#P00240;FGF signaling pathway#P00021>FRS2#P00635 MONDO|Ensembl=ENSMODG00000014381.4|UniProtKB=A0A5F8GTN0 A0A5F8GTN0 IL18 PTHR10078:SF35 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-18 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125 response to lipopolysaccharide#GO:0032496;cell surface receptor signaling pathway#GO:0007166;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to peptide#GO:1901652;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to molecule of bacterial origin#GO:0002237;cellular response to molecule of bacterial origin#GO:0071219;defense response#GO:0006952;response to external stimulus#GO:0009605;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;response to bacterium#GO:0009617;inflammatory response#GO:0006954;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;interleukin superfamily#PC00128;cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870;Toll receptor signaling pathway#P00054>Gene trancription#G01550;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>INFgamma#P00878;Interleukin signaling pathway#P00036>Interleukin#P00970 MONDO|Ensembl=ENSMODG00000047037.1|UniProtKB=A0A5F8HHU1 A0A5F8HHU1 LOC130456194 PTHR28333:SF2 NUCLEAR FRAGILE X MENTAL RETARDATION-INTERACTING PROTEIN 2 FMR1-INTERACTING PROTEIN NUFIP2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;nucleoplasm#GO:0005654;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000011265.5|UniProtKB=F6PK57 F6PK57 AKAP4 PTHR10226:SF8 A KINASE ANCHOR PROTEIN A-KINASE ANCHOR PROTEIN 4 binding#GO:0005488;protein kinase A binding#GO:0051018;protein binding#GO:0005515 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;macromolecule localization#GO:0033036;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;localization#GO:0051179;cell communication#GO:0007154;intracellular protein localization#GO:0008104;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166 sperm principal piece#GO:0097228;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014510.4|UniProtKB=F7ERN9 F7ERN9 KRT35 PTHR23239:SF193 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA5 structural molecule activity#GO:0005198 intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;morphogenesis of an epithelium#GO:0002009;organelle organization#GO:0006996;cellular process#GO:0009987;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;cytoskeleton organization#GO:0007010 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000020781.4|UniProtKB=A0A5F8GEP8 A0A5F8GEP8 CDS1 PTHR13773:SF16 PHOSPHATIDATE CYTIDYLYLTRANSFERASE PHOSPHATIDATE CYTIDYLYLTRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 lipid droplet organization#GO:0034389;organelle assembly#GO:0070925;organophosphate biosynthetic process#GO:0090407;cellular component organization#GO:0016043;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;membraneless organelle assembly#GO:0140694;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;lipid storage#GO:0019915;organophosphate metabolic process#GO:0019637;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;cellular component assembly#GO:0022607 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 transferase#PC00220 MONDO|Ensembl=ENSMODG00000014622.4|UniProtKB=A0A5F8HEY3 A0A5F8HEY3 CYP4F22 PTHR24291:SF53 CYTOCHROME P450 FAMILY 4 ULTRA-LONG-CHAIN FATTY ACID OMEGA-HYDROXYLASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000011849.3|UniProtKB=F7GDN3 F7GDN3 PTHR46962:SF1 SERINE/THREONINE-PROTEIN KINASE KIST SERINE_THREONINE-PROTEIN KINASE KIST transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;ribonucleoprotein complex binding#GO:0043021 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of translational initiation#GO:0006446;positive regulation of protein metabolic process#GO:0051247;regulation of protein localization#GO:0032880;positive regulation of translation#GO:0045727;regulation of establishment of protein localization#GO:0070201;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;post-transcriptional regulation of gene expression#GO:0010608;regulation of localization#GO:0032879;regulation of transport#GO:0051049;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuron projection cytoplasm#GO:0120111;membraneless organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;neuron projection#GO:0043005 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000039253.1|UniProtKB=A0A5F8GJ98 A0A5F8GJ98 CASP14 PTHR10454:SF131 CASPASE CASPASE-14 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;positive regulation of apoptotic process#GO:0043065;developmental process#GO:0032502;regulation of apoptotic process#GO:0042981;positive regulation of neuron apoptotic process#GO:0043525;epidermis development#GO:0008544;biological regulation#GO:0065007;tissue development#GO:0009888;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000009113.3|UniProtKB=A0A5F8GKU5 A0A5F8GKU5 PTHR11588:SF298 TUBULIN TUBULIN ALPHA-1C CHAIN GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198 cell cycle#GO:0007049;cellular component organization#GO:0016043;cell differentiation#GO:0030154;mitotic cell cycle#GO:0000278;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;microtubule-based process#GO:0007017;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 tubulin#PC00228;cytoskeletal protein#PC00085 Gonadotropin-releasing hormone receptor pathway#P06664>Tubulin#P06772 MONDO|Ensembl=ENSMODG00000011856.3|UniProtKB=A0A5F8H4E8 A0A5F8H4E8 PTHR11875:SF70 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1 LIKE 6 histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;protein binding#GO:0005515 protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;chromatin remodeling#GO:0006338;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000015096.4|UniProtKB=F6VSV2 F6VSV2 ZBTB12 PTHR24399:SF38 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 12 sequence-specific DNA binding#GO:0043565;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000039233.1|UniProtKB=A0A5F8HF81 A0A5F8HF81 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012467.4|UniProtKB=F6Q4M9 F6Q4M9 SCRN2 PTHR12994:SF16 SECERNIN SECERNIN-2 MONDO|Ensembl=ENSMODG00000038508.1|UniProtKB=A0A5F8GCS0 A0A5F8GCS0 PTHR11905:SF148 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 30 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 metabolic process#GO:0008152;development of primary male sexual characteristics#GO:0046546;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;male sex differentiation#GO:0046661;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;animal organ development#GO:0048513;male gonad development#GO:0008584;cellular process#GO:0009987;sex differentiation#GO:0007548;multicellular organismal process#GO:0032501;gonad development#GO:0008406;proteolysis#GO:0006508;animal gross anatomical part developmental process#GO:0160108;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;system development#GO:0048731;reproductive system development#GO:0061458;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;reproductive structure development#GO:0048608 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;plasma membrane#GO:0005886;cell surface#GO:0009986;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000002549.3|UniProtKB=F7ALT7 F7ALT7 DHX38 PTHR18934:SF91 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000047912.1|UniProtKB=A0A5F8H117 A0A5F8H117 PTHR22380:SF1 TESTIS-EXPRESSED PROTEIN 15 TESTIS-EXPRESSED PROTEIN 15 nuclear chromosome segregation#GO:0098813;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;gamete generation#GO:0007276;regulation of double-strand break repair via homologous recombination#GO:0010569;nuclear division#GO:0000280;regulation of DNA recombination#GO:0000018;regulation of cellular response to stress#GO:0080135;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;synaptonemal complex assembly#GO:0007130;homologous chromosome pairing at meiosis#GO:0007129;male meiotic nuclear division#GO:0007140;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;chromosome segregation#GO:0007059;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;multicellular organismal reproductive process#GO:0048609;regulation of double-strand break repair#GO:2000779;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;male gamete generation#GO:0048232;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;meiotic nuclear division#GO:0140013;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000006783.5|UniProtKB=A0A5F8GYE2 A0A5F8GYE2 PLCB3 PTHR10336:SF11 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-3 hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;calmodulin binding#GO:0005516;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;binding#GO:0005488;hydrolase activity#GO:0016787;protein binding#GO:0005515 calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;metabolic process#GO:0008152;glycerophospholipid metabolic process#GO:0006650;monoatomic cation transmembrane transport#GO:0098655;signal transduction#GO:0007165;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;G protein-coupled receptor signaling pathway#GO:0007186;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;signaling#GO:0023052;calcium ion transmembrane transport#GO:0070588;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;transport#GO:0006810;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;organophosphate metabolic process#GO:0019637;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262;phospholipase#PC00186 Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744;Endothelin signaling pathway#P00019>PLCbeta#P00591;Endogenous cannabinoid signaling#P05730>PLC#P05746;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PLC#P05933;Wnt signaling pathway#P00057>Phospholipase C#P01443;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;2-arachidonoylglycerol biosynthesis#P05726>PLC#P05738;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 MONDO|Ensembl=ENSMODG00000002772.3|UniProtKB=A0A5F8H4J2 A0A5F8H4J2 LOC100020348 PTHR24300:SF437 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C44 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;tetrapyrrole binding#GO:0046906;binding#GO:0005488 response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000001014.4|UniProtKB=F6ZFA4 F6ZFA4 IGF2BP3 PTHR10288:SF158 KH DOMAIN CONTAINING RNA BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 3 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;mRNA stabilization#GO:0048255;animal gross anatomical part developmental process#GO:0160108;RNA stabilization#GO:0043489;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of RNA catabolic process#GO:1902369;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA stability#GO:0043487;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000025192.2|UniProtKB=F7C0L7 F7C0L7 PTHR19861:SF0 WD40 REPEAT PROTEIN SWD2 WD REPEAT-CONTAINING PROTEIN 82 binding#GO:0005488;chromatin binding#GO:0003682 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000012236.3|UniProtKB=F6Z6F9 F6Z6F9 LOC100026384 PTHR11214:SF217 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000024416.2|UniProtKB=F7GFS0 F7GFS0 LRRN1 PTHR24373:SF97 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT NEURONAL PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013291.3|UniProtKB=A0A5F8GY53 A0A5F8GY53 PTHR32341:SF13 INTERFERON-INDUCIBLE GTPASE GTP-BINDING PROTEIN ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 immune response#GO:0006955;response to other organism#GO:0051707;macroautophagy#GO:0016236;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;response to external biotic stimulus#GO:0043207;catabolic process#GO:0009056;organelle assembly#GO:0070925;vacuole organization#GO:0007033;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;defense response to symbiont#GO:0140546;response to stress#GO:0006950;organelle organization#GO:0006996;response to biotic stimulus#GO:0009607;cellular component biogenesis#GO:0044085;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;cellular component assembly#GO:0022607;response to chemical#GO:0042221;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;cellular response to cytokine stimulus#GO:0071345;cellular component organization#GO:0016043;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;immune system process#GO:0002376;response to peptide#GO:1901652;process utilizing autophagic mechanism#GO:0061919 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000012019.4|UniProtKB=F7AM72 F7AM72 PTHR44858:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 6 TETRATRICOPEPTIDE REPEAT DOMAIN 6 MONDO|Ensembl=ENSMODG00000012553.4|UniProtKB=F6PLR8 F6PLR8 TMEM245 PTHR21716:SF4 TRANSMEMBRANE PROTEIN TRANSMEMBRANE PROTEIN 245 cellular process#GO:0009987;transport#GO:0006810;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000012973.3|UniProtKB=F7DB90 F7DB90 AMT PTHR43757:SF2 AMINOMETHYLTRANSFERASE AMINOMETHYLTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 transferase#PC00220;methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000007066.4|UniProtKB=A0A5F8GML8 A0A5F8GML8 NCS1 PTHR23055:SF198 CALCIUM BINDING PROTEINS NEURONAL CALCIUM SENSOR 1 enzyme activator activity#GO:0008047;cyclase regulator activity#GO:0010851;molecular function regulator activity#GO:0098772;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;molecular function activator activity#GO:0140677;cation binding#GO:0043169 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000024373.2|UniProtKB=F6ZTC1 F6ZTC1 FUT4 PTHR11929:SF132 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE 4 catalytic activity#GO:0003824;transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;alpha-(1->3)-fucosyltransferase activity#GO:0046920 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000000504.4|UniProtKB=F6Y669 F6Y669 ZRANB2 PTHR12999:SF26 ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 ZRANB2-RELATED ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 lipid binding#GO:0008289;carbohydrate derivative binding#GO:0097367;binding#GO:0005488;lipopolysaccharide binding#GO:0001530 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000005477.5|UniProtKB=F7CG14 F7CG14 PDCD2 PTHR12298:SF8 PCDC2 PROGRAMMED CELL DEATH PROTEIN 2 -RELATED US5 ASSEMBLY CHAPERONE PDCD2 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000043325.1|UniProtKB=A0A5F8G5J2 A0A5F8G5J2 PTHR14208:SF0 BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN EIF5-MIMIC PROTEIN 2 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 basic leucine zipper transcription factor#PC00056 MONDO|Ensembl=ENSMODG00000006575.3|UniProtKB=F7B859 F7B859 RIDA PTHR11803:SF53 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA 2-IMINOBUTANOATE_2-IMINOPROPANOATE DEAMINASE catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of protein metabolic process#GO:0051248;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of translation#GO:0017148;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000001075.4|UniProtKB=F7GI05 F7GI05 KLHL7 PTHR24412:SF435 KELCH PROTEIN KELCH-LIKE PROTEIN 7 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005061.3|UniProtKB=F7ASY3 F7ASY3 TIMM44 PTHR10721:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907 mitochondrion#GO:0005739;organelle lumen#GO:0043233;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090 transporter#PC00227 MONDO|Ensembl=ENSMODG00000014352.4|UniProtKB=F6U510 F6U510 TAP1 PTHR24221:SF249 ATP-BINDING CASSETTE SUB-FAMILY B ANTIGEN PEPTIDE TRANSPORTER 1 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;protein binding#GO:0005515;binding#GO:0005488;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626 immune system process#GO:0002376;transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;antigen processing and presentation#GO:0019882;transmembrane transport#GO:0055085;localization#GO:0051179 membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000009095.4|UniProtKB=A0A5F8G5P3 A0A5F8G5P3 SDR16C5 PTHR24322:SF728 PKSB EPIDERMAL RETINOL DEHYDROGENASE 2 catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745 hormone metabolic process#GO:0042445;biological regulation#GO:0065007;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;terpenoid metabolic process#GO:0006721 organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000049197.1|UniProtKB=A0A5F8HAM2 A0A5F8HAM2 MRPS2 PTHR12534:SF0 30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR SMALL RIBOSOMAL SUBUNIT PROTEIN US2M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000018713.4|UniProtKB=F7FCD2 F7FCD2 FMO5 PTHR23023:SF78 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE 5 monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000049121.1|UniProtKB=F6PJJ7 F6PJJ7 LOC100009897 PTHR26453:SF108 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013671.4|UniProtKB=F6VGJ7 F6VGJ7 PTHR24377:SF975 IP01015P-RELATED ZINC FINGER PROTEIN 883-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009947.4|UniProtKB=A0A5F8GWP9 A0A5F8GWP9 DCLK1 PTHR24347:SF401 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE DCLK1 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 neuron differentiation#GO:0030182;growth#GO:0040007;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell growth#GO:0016049;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;axon extension#GO:0048675;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;developmental growth involved in morphogenesis#GO:0060560;axonogenesis#GO:0007409;neuron projection extension#GO:1990138;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;developmental growth#GO:0048589;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;axon development#GO:0061564;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;anatomical structure development#GO:0048856;system development#GO:0048731;developmental cell growth#GO:0048588 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000050809.1|UniProtKB=A0A5F8GCQ0 A0A5F8GCQ0 SMIM22 PTHR36982:SF3 CLCA DOMAIN-CONTAINING PROTEIN SMALL INTEGRAL MEMBRANE PROTEIN 22 regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological process#GO:0050789 MONDO|Ensembl=ENSMODG00000028307.2|UniProtKB=K7E665 K7E665 LOC100617165 PTHR10206:SF2 CATHELICIDIN CATHELICIDIN ANTIMICROBIAL PEPTIDE carbohydrate derivative binding#GO:0097367;binding#GO:0005488;lipopolysaccharide binding#GO:0001530;lipid binding#GO:0008289 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to other organism#GO:0051707;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;defense response to Gram-negative bacterium#GO:0050829;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051 MONDO|Ensembl=ENSMODG00000000222.4|UniProtKB=F6SZ44 F6SZ44 ANKRD49 PTHR24134:SF9 ANKYRIN REPEAT-CONTAINING PROTEIN DDB_G0279043 ANKYRIN REPEAT AND SOCS BOX PROTEIN 8 MONDO|Ensembl=ENSMODG00000045010.1|UniProtKB=A0A5F8H7R0 A0A5F8H7R0 PTHR31383:SF2 OXIDATIVE STRESS-RESPONSE SERINE-RICH PROTEIN 1 OXIDATIVE STRESS-RESPONSIVE SERINE-RICH PROTEIN 1 MONDO|Ensembl=ENSMODG00000003082.3|UniProtKB=F6PL62 F6PL62 PTHR11818:SF144 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN 1 structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600;visual perception#GO:0007601;visual system development#GO:0150063;sensory perception of light stimulus#GO:0050953;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;sensory organ development#GO:0007423;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;multicellular organismal process#GO:0032501;sensory system development#GO:0048880 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000009480.3|UniProtKB=F7FNJ3 F7FNJ3 RNF103 PTHR15302:SF0 E3 UBIQUITIN-PROTEIN LIGASE RNF103 E3 UBIQUITIN-PROTEIN LIGASE RNF103 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;ERAD pathway#GO:0036503;protein modification by small protein conjugation or removal#GO:0070647;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;response to stress#GO:0006950;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000019065.4|UniProtKB=A0A5F8GM09 A0A5F8GM09 TUSC3 PTHR12692:SF1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT TUSC3 establishment of localization#GO:0051234;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;transport#GO:0006810;glycoprotein metabolic process#GO:0009100;magnesium ion transport#GO:0015693;metabolic process#GO:0008152;monoatomic ion transmembrane transport#GO:0034220;biosynthetic process#GO:0009058;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;protein metabolic process#GO:0019538;localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487 membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000013335.4|UniProtKB=F7GAG8 F7GAG8 ANKRD9 PTHR24133:SF16 ANKYRIN DOMAIN-CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 9 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019028.4|UniProtKB=F7BLJ4 F7BLJ4 RPL7L1 PTHR11524:SF13 60S RIBOSOMAL PROTEIN L7 RIBOSOMAL PROTEIN UL30-LIKE binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000013038.4|UniProtKB=A0A5F8GRN7 A0A5F8GRN7 PTHR45818:SF4 PROTEIN VAV GUANINE NUCLEOTIDE EXCHANGE FACTOR VAV2 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cell surface receptor signaling pathway#GO:0007166;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;immune response-regulating cell surface receptor signaling pathway#GO:0002768;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;positive regulation of cellular process#GO:0048522 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 B cell activation#P00010>vav#P00368;T cell activation#P00053>vav#P01295;PDGF signaling pathway#P00047>Vav#P01169 MONDO|Ensembl=ENSMODG00000019357.4|UniProtKB=A0A5F8GUS1 A0A5F8GUS1 SEC31B PTHR13923:SF22 SEC31-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC31B cellular component organization#GO:0016043;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;coated membrane#GO:0048475;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000001960.4|UniProtKB=F6VJ30 F6VJ30 AVPR1B PTHR24241:SF18 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR VASOPRESSIN V1B RECEPTOR G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;circulatory system process#GO:0003013;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell communication#GO:0007154;regulation of biological quality#GO:0065008;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;response to chemical#GO:0042221;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of system process#GO:0044057;regulation of anatomical structure size#GO:0090066;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014900.4|UniProtKB=A0A5F8H6S0 A0A5F8H6S0 BNC2 PTHR15021:SF2 DISCONNECTED-RELATED ZINC FINGER PROTEIN BASONUCLIN-2 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000020592.4|UniProtKB=F7A0N4 F7A0N4 GUF1 PTHR43512:SF7 TRANSLATION FACTOR GUF1-RELATED TRANSLATION FACTOR GUF1, MITOCHONDRIAL binding#GO:0005488;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021 biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of translation#GO:0045727;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000016034.4|UniProtKB=F6YV18 F6YV18 PKD1 PTHR46730:SF3 POLYCYSTIN-1 POLYCYSTIN-1 monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;metal ion transport#GO:0030001 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000009398.4|UniProtKB=F7CP58 F7CP58 RGS20 PTHR10845:SF277 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 20 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 MONDO|Ensembl=ENSMODG00000020652.4|UniProtKB=F7E6B1 F7E6B1 TACR3 PTHR46925:SF1 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED NEUROMEDIN-K RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188 regulation of cellular process#GO:0050794;regulation of reproductive process#GO:2000241;regulation of microtubule-based movement#GO:0060632;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;positive regulation of cell motility#GO:2000147;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017;regulation of microtubule-based process#GO:0032886 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;9+2 motile cilium#GO:0097729 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000002631.3|UniProtKB=A0A5F8GQ46 A0A5F8GQ46 PSMD7 PTHR10540:SF7 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;proteasome regulatory particle, lid subcomplex#GO:0008541;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;proteasome complex#GO:0000502 translation initiation factor#PC00224 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 MONDO|Ensembl=ENSMODG00000001207.4|UniProtKB=A0A5F8GNS5 A0A5F8GNS5 DNAAF11 PTHR18849:SF21 LEUCINE RICH REPEAT PROTEIN DYNEIN AXONEMAL ASSEMBLY FACTOR 11 outer dynein arm assembly#GO:0036158;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000013509.4|UniProtKB=F7DRN4 F7DRN4 PLLP PTHR22776:SF9 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN PLASMOLIPIN cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;anatomical structure development#GO:0048856;system development#GO:0048731;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;myelination#GO:0042552 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;myelin sheath#GO:0043209;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005917.4|UniProtKB=F6WX74 F6WX74 GABRQ PTHR18945:SF579 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT THETA ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594;chloride channel activity#GO:0005254;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023 transport#GO:0006810;chloride transport#GO:0006821;establishment of localization#GO:0051234;cellular process#GO:0009987;synaptic signaling#GO:0099536;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic anion transmembrane transport#GO:0098656;trans-synaptic signaling#GO:0099537;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;localization#GO:0051179;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916 signaling receptor complex#GO:0043235;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000010504.4|UniProtKB=F7EAC0 F7EAC0 PTHR24338:SF9 HOMEOBOX PROTEIN MSX HOMEOBOX PROTEIN MSX-3 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;developmental process#GO:0032502;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000006986.3|UniProtKB=F6QA02 F6QA02 BORCS8 PTHR21146:SF3 MEF2B PROTEIN BLOC-1-RELATED COMPLEX SUBUNIT 8 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 p38 MAPK pathway#P05918>MEF#P06023 MONDO|Ensembl=ENSMODG00000014605.5|UniProtKB=F6ZEN2 F6ZEN2 SMG8 PTHR13091:SF0 AMPLIFIED IN BREAST CANCER 2-RELATED NONSENSE-MEDIATED MRNA DECAY FACTOR SMG8 RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605 MONDO|Ensembl=ENSMODG00000000999.4|UniProtKB=F7EA27 F7EA27 FBXL18 PTHR16134:SF19 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 18 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 catalytic complex#GO:1902494;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000012384.4|UniProtKB=F6PNM0 F6PNM0 C18orf63 PTHR28495:SF1 HYPOTHETICAL PROTEIN LOC100359752 GENE, 17266-RELATED reproductive structure development#GO:0048608;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;reproductive system development#GO:0061458;system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;gonad development#GO:0008406;multicellular organismal process#GO:0032501;sex differentiation#GO:0007548;male gonad development#GO:0008584;animal organ development#GO:0048513;multicellular organism development#GO:0007275;male sex differentiation#GO:0046661;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;development of primary male sexual characteristics#GO:0046546 MONDO|Ensembl=ENSMODG00000006177.2|UniProtKB=F7B516 F7B516 NKX2-2 PTHR24340:SF24 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000009308.4|UniProtKB=F7GK01 F7GK01 NOX5 PTHR11972:SF58 NADPH OXIDASE NADPH OXIDASE 5 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651 cellular process#GO:0009987;metabolic process#GO:0008152;response to stress#GO:0006950;reactive oxygen species metabolic process#GO:0072593;defense response#GO:0006952;superoxide metabolic process#GO:0006801;response to stimulus#GO:0050896 catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 metabolite interconversion enzyme#PC00262;oxidase#PC00175 MONDO|Ensembl=ENSMODG00000017657.4|UniProtKB=F6YJX5 F6YJX5 PABPC4 PTHR24012:SF365 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 4 nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;single-stranded RNA binding#GO:0003727 post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;cytosol#GO:0005829;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000014664.4|UniProtKB=F7E828 F7E828 STRIP2 PTHR13239:SF6 PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2 STRIATIN-INTERACTING PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of hippo signaling#GO:0035331;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000029727.2|UniProtKB=K7E2C5 K7E2C5 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000003911.3|UniProtKB=F7CNW2 F7CNW2 MARVELD1 PTHR22776:SF28 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MARVEL DOMAIN-CONTAINING PROTEIN 1 biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007207.2|UniProtKB=F6WTF0 F6WTF0 LDAF1 PTHR14275:SF0 PROMETHIN LIPID DROPLET ASSEMBLY FACTOR 1 MONDO|Ensembl=ENSMODG00000046903.1|UniProtKB=A0A5F8G2K9 A0A5F8G2K9 PTHR44826:SF14 SPORE COAT PROTEIN SP85 G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000019233.3|UniProtKB=F6RDW6 F6RDW6 IFT20 PTHR31978:SF3 INTRAFLAGELLAR TRANSPORT PROTEIN 20 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 20 HOMOLOG plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;localization#GO:0051179;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;protein localization to cilium#GO:0061512 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;ciliary base#GO:0097546;neuron projection#GO:0043005;membraneless organelle#GO:0043228;centrosome#GO:0005813;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000011011.4|UniProtKB=F6ZBV9 F6ZBV9 USP3 PTHR21646:SF19 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 3 catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of biological quality#GO:0065008;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of protein stability#GO:0031647;response to stress#GO:0006950 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000010607.4|UniProtKB=A0A5F8HCV9 A0A5F8HCV9 CCM2 PTHR21642:SF4 CEREBRAL CAVERNOUS MALFORMATIONS PROTEIN 2 HOMOLOG CEREBRAL CAVERNOUS MALFORMATIONS 2 PROTEIN blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;circulatory system development#GO:0072359;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;system development#GO:0048731;cellular process#GO:0009987;heart development#GO:0007507;vasculogenesis#GO:0001570;multicellular organismal process#GO:0032501;tube development#GO:0035295;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;animal organ development#GO:0048513;vasculature development#GO:0001944 EGF receptor signaling pathway#P00018>MEKK1-5#P00553 MONDO|Ensembl=ENSMODG00000029014.2|UniProtKB=K7E166 K7E166 PTHR12067:SF5 PODOCALYXIN PODOCALYXIN regulation of biological process#GO:0050789;positive regulation of cell adhesion#GO:0045785;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;regulation of cell adhesion mediated by integrin#GO:0033628;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;cell motility#GO:0048870;regulation of cell projection assembly#GO:0060491;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of cell-cell adhesion#GO:0022409;biological regulation#GO:0065007;negative regulation of cell adhesion#GO:0007162;negative regulation of cell-cell adhesion#GO:0022408;regulation of cell adhesion#GO:0030155;cell migration#GO:0016477;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of plasma membrane bounded cell projection organization#GO:0120035 cell projection membrane#GO:0031253;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;actin-based cell projection#GO:0098858;microvillus#GO:0005902;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;plasma membrane region#GO:0098590;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000016367.4|UniProtKB=F7ERT4 F7ERT4 COG5 PTHR13228:SF3 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;intra-Golgi vesicle-mediated transport#GO:0006891;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular process#GO:0009987 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;COG complex#GO:0017119;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000000174.3|UniProtKB=A0A5F8GIU4 A0A5F8GIU4 ASCL5 PTHR13935:SF55 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE HOMOLOG 5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000016030.4|UniProtKB=F6ZHT5 F6ZHT5 MOG PTHR24100:SF71 BUTYROPHILIN MYELIN-OLIGODENDROCYTE GLYCOPROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000018440.3|UniProtKB=A0A5F8HJG8 A0A5F8HJG8 PTHR11241:SF0 DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;cation binding#GO:0043169;magnesium ion binding#GO:0000287;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide catabolic process#GO:0009166;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside monophosphate metabolic process#GO:0009123;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate biosynthetic process#GO:0009124 phosphatase#PC00181;hydrolase#PC00121 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUTP pyrophosphatase#P02918 MONDO|Ensembl=ENSMODG00000015718.4|UniProtKB=F7B5V1 F7B5V1 PREB PTHR23284:SF0 PROLACTIN REGULATORY ELEMENT BINDING PROTEIN GUANINE NUCLEOTIDE-EXCHANGE FACTOR SEC12 protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membrane organization#GO:0061024;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000012616.4|UniProtKB=F6S2P5 F6S2P5 PTHR24377:SF641 IP01015P-RELATED ZINC FINGER PROTEIN 354B DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000000528.4|UniProtKB=F6Y4X0 F6Y4X0 PLCB2 PTHR10336:SF10 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-2 lipase activity#GO:0016298;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081 regulation of biological process#GO:0050789;calcium ion transmembrane transport#GO:0070588;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;signal transduction#GO:0007165;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;glycerophospholipid metabolic process#GO:0006650;metabolic process#GO:0008152;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;metal ion transport#GO:0030001;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 lipase#PC00143;metabolite interconversion enzyme#PC00262;phospholipase#PC00186;hydrolase#PC00121 Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;2-arachidonoylglycerol biosynthesis#P05726>PLC#P05738;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Wnt signaling pathway#P00057>Phospholipase C#P01443;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PLC#P05933;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Endogenous cannabinoid signaling#P05730>PLC#P05746;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Endothelin signaling pathway#P00019>PLCbeta#P00591;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744 MONDO|Ensembl=ENSMODG00000002357.4|UniProtKB=F7GDM4 F7GDM4 RNF213 PTHR22605:SF16 RZ-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF213 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755 angiogenesis#GO:0001525;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;sprouting angiogenesis#GO:0002040;animal gross anatomical part developmental process#GO:0160108;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;circulatory system development#GO:0072359;regulation of Wnt signaling pathway#GO:0030111;negative regulation of biological process#GO:0048519;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;system development#GO:0048731;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;multicellular organismal process#GO:0032501;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;tube development#GO:0035295 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000015194.2|UniProtKB=F7BVS9 F7BVS9 LRRC4 PTHR24369:SF9 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4 binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632 regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;postsynapse organization#GO:0099173;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;synapse organization#GO:0050808;localization within membrane#GO:0051668;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;postsynaptic specialization organization#GO:0099084;macromolecule localization#GO:0033036;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;membrane organization#GO:0061024;developmental process#GO:0032502;intracellular protein localization#GO:0008104;cell junction assembly#GO:0034329;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;synapse assembly#GO:0007416;excitatory synapse assembly#GO:1904861;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;postsynaptic density organization#GO:0097106;cellular localization#GO:0051641;synaptic membrane adhesion#GO:0099560;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular component assembly#GO:0022607;regulation of trans-synaptic signaling#GO:0099177;nervous system development#GO:0007399;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;glutamatergic synapse#GO:0098978;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000043192.1|UniProtKB=F6YRD6 F6YRD6 LOC100019634 PTHR26452:SF828 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000004244.5|UniProtKB=F6UB49 F6UB49 ZFHX2 PTHR45891:SF1 ZINC FINGER HOMEOBOX PROTEIN ZINC FINGER HOMEOBOX PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000007810.5|UniProtKB=F7ETW9 F7ETW9 NUMBL PTHR47368:SF4 NUMB NUMB-LIKE PROTEIN regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nervous system development#GO:0051960;regulation of cellular process#GO:0050794;positive regulation of nervous system development#GO:0051962;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000020102.3|UniProtKB=F7ESA0 F7ESA0 TIMM10 PTHR11038:SF16 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597 mitochondrial transport#GO:0006839;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;protein insertion into mitochondrial inner membrane#GO:0045039;mitochondrial protein import pathway#GO:7770058;organelle organization#GO:0006996;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular transport#GO:0046907;transport#GO:0006810 protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;TIM22 mitochondrial import inner membrane insertion complex#GO:0042721;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000014435.5|UniProtKB=F7AUI3 F7AUI3 RNF20 PTHR23163:SF2 RING FINGER PROTEIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE BRE1A catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000005623.1|UniProtKB=F7CFG8 F7CFG8 GNG10 PTHR13809:SF6 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-10 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;membrane protein complex#GO:0098796;extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562;catalytic complex#GO:1902494 heterotrimeric G-protein#PC00117 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Enkephalin release#P05913>G-Protein (s)#P05977;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (i)#P05974;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;GABA-B receptor II signaling#P05731>Ggamma#P05754;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Wnt signaling pathway#P00057>Ggamma#P01465;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002 MONDO|Ensembl=ENSMODG00000009283.5|UniProtKB=F7DQ20 F7DQ20 RHBDF2 PTHR45965:SF2 INACTIVE RHOMBOID PROTEIN INACTIVE RHOMBOID PROTEIN 2 regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of cell communication#GO:0010646;regulation of protein secretion#GO:0050708;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;regulation of secretion#GO:0051046;regulation of secretion by cell#GO:1903530;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201;regulation of signaling#GO:0023051 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000017209.2|UniProtKB=F6XEV7 F6XEV7 CA5B PTHR18952:SF25 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 5B, MITOCHONDRIAL catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 MONDO|Ensembl=ENSMODG00000027907.2|UniProtKB=K7E401 K7E401 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008048.4|UniProtKB=F6ZA02 F6ZA02 GATA2 PTHR10071:SF149 TRANSCRIPTION FACTOR GATA FAMILY MEMBER ENDOTHELIAL TRANSCRIPTION FACTOR GATA-2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of vasculature development#GO:1901342;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of angiogenesis#GO:0045765;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of anatomical structure morphogenesis#GO:0022603;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cell fate commitment#GO:0045165;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;positive regulation of angiogenesis#GO:0045766;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>GATA2/4#P06859 MONDO|Ensembl=ENSMODG00000010383.4|UniProtKB=F7AV91 F7AV91 NDFIP1 PTHR13396:SF3 NEDD4 FAMILY INTERACTING PROTEIN 1/2 NEDD4 FAMILY-INTERACTING PROTEIN 1 positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of protein ubiquitination#GO:0031396;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of protein modification process#GO:0031399;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000047188.1|UniProtKB=A0A5F8GKQ2 A0A5F8GKQ2 PTHR37884:SF1 SEPTIN 4 SEPTIN-4 Parkinson disease#P00049>CDCrel-1#P01226 MONDO|Ensembl=ENSMODG00000010287.4|UniProtKB=F6V7Z1 F6V7Z1 YIPF5 PTHR21236:SF6 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF5 vesicle fusion#GO:0006906;regulation of cellular process#GO:0050794;Golgi organization#GO:0007030;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular component organization#GO:0016043;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;membrane fusion#GO:0061025;organelle organization#GO:0006996;vesicle organization#GO:0016050;regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;Golgi apparatus subcompartment#GO:0098791 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000039105.1|UniProtKB=A0A5F8GI46 A0A5F8GI46 LOC100619367 PTHR10806:SF28 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11A hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;peptidase complex#GO:1905368;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 serine protease#PC00203 Endothelin signaling pathway#P00019>signal peptidase#P00573;Vasopressin synthesis#P04395>Signal Peptidase#P04589 MONDO|Ensembl=ENSMODG00000046879.1|UniProtKB=F7AFM2 F7AFM2 PTHR24028:SF318 CADHERIN-87A PROTOCADHERIN BETA-16 cell adhesion#GO:0007155;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000005691.4|UniProtKB=F6UKU7 F6UKU7 SERPINB1 PTHR11461:SF180 SERINE PROTEASE INHIBITOR, SERPIN LEUKOCYTE ELASTASE INHIBITOR enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000018189.4|UniProtKB=F7B797 F7B797 UPK1B PTHR19282:SF514 TETRASPANIN UROPLAKIN-1B plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010328.6|UniProtKB=F6XLL0 F6XLL0 KAT6A PTHR10615:SF26 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT6A catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;histone acetyltransferase activity#GO:0004402;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;chromatin binding#GO:0003682;N-acetyltransferase activity#GO:0008080;protein N-acetyltransferase activity#GO:0034212;transferase activity#GO:0016740;protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;binding#GO:0005488;acetyltransferase activity#GO:0016407;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000049861.1|UniProtKB=A0A5F8GTC5 A0A5F8GTC5 MOSMO PTHR31186:SF1 MODULATOR OF SMOOTHENED PROTEIN MODULATOR OF SMOOTHENED PROTEIN regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585 cell periphery#GO:0071944;membrane#GO:0016020;ciliary membrane#GO:0060170;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell projection membrane#GO:0031253 MONDO|Ensembl=ENSMODG00000023524.3|UniProtKB=F7GLH8 F7GLH8 PTHR24376:SF258 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 814 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000049961.1|UniProtKB=A0A5F8G1U6 A0A5F8G1U6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000027374.2|UniProtKB=F6YDJ5 F6YDJ5 LOC103098166 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017364.4|UniProtKB=F6W8M3 F6W8M3 LOC100022049 PTHR19143:SF467 FIBRINOGEN/TENASCIN/ANGIOPOEITIN MGC64358 PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000015350.3|UniProtKB=F6WY84 F6WY84 VSIG10 PTHR12231:SF222 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10 protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell junction#GO:0030054;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000011388.2|UniProtKB=A0A5F8G515 A0A5F8G515 PTHR24231:SF25 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000003538.2|UniProtKB=F7GBP9 F7GBP9 PTHR48018:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8B8 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015846.4|UniProtKB=A0A5F8G2N2 A0A5F8G2N2 DTNB PTHR12268:SF22 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROBREVIN BETA cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;nervous system development#GO:0007399;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000016820.4|UniProtKB=A0A5F8G6H3 A0A5F8G6H3 SEC61A2 PTHR10906:SF10 SECY/SEC61-ALPHA FAMILY MEMBER PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT ALPHA ISOFORM 2 protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;transmembrane protein transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;protein targeting to membrane#GO:0006612;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting#GO:0006605;localization within membrane#GO:0051668;post-translational protein targeting to membrane, translocation#GO:0031204;protein transport#GO:0015031;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;rough endoplasmic reticulum#GO:0005791;rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 transporter#PC00227 MONDO|Ensembl=ENSMODG00000025248.2|UniProtKB=F7F5X1 F7F5X1 PTHR24070:SF455 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY SMALL MONOMERIC GTPASE ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;EGF receptor signaling pathway#P00018>Ras#P00552;PDGF signaling pathway#P00047>Ras#P01154;Ras Pathway#P04393>Ras#P04547;Integrin signalling pathway#P00034>Ras#P00916;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;VEGF signaling pathway#P00056>Ras#P01411;Angiogenesis#P00005>Ras#P00238;p53 pathway feedback loops 2#P04398>Ras#P04651;FGF signaling pathway#P00021>Ras#P00633 MONDO|Ensembl=ENSMODG00000005174.4|UniProtKB=F7E7H1 F7E7H1 TVP23A PTHR13019:SF18 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 HOMOLOG A export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;protein localization to extracellular region#GO:0071692;cellular process#GO:0009987;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein transport#GO:0015031;establishment of protein localization to extracellular region#GO:0035592;secretion by cell#GO:0032940;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;secretion#GO:0046903;protein secretion#GO:0009306;localization#GO:0051179;transport#GO:0006810 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000000833.3|UniProtKB=F6RQ17 F6RQ17 FOXRED2 PTHR43539:SF23 FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220) FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976 endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000038875.1|UniProtKB=A0A5F8G3B1 A0A5F8G3B1 PTHR13511:SF0 KXDL MOTIF-CONTAINING PROTEIN 1 KXDL MOTIF-CONTAINING PROTEIN 1 localization#GO:0051179;organelle localization#GO:0051640;lysosome localization#GO:0032418 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000000794.4|UniProtKB=F6SS23 F6SS23 MMP13 PTHR10201:SF165 MATRIX METALLOPROTEINASE COLLAGENASE 3 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular component organization#GO:0016043;cellular process#GO:0009987;catabolic process#GO:0009056;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130;Plasminogen activating cascade#P00050>pro-MMP-13#P01254;Plasminogen activating cascade#P00050>MMP-13#P01250 MONDO|Ensembl=ENSMODG00000009474.3|UniProtKB=A0A5F8GH91 A0A5F8GH91 LOC130453558 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019549.4|UniProtKB=F6UTU2 F6UTU2 SDCBP2 PTHR12345:SF13 SYNTENIN RELATED SYNTENIN-2 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000012909.3|UniProtKB=F7GKP7 F7GKP7 ZPBP2 PTHR15443:SF4 ZONA PELLUCIDA BINDING PROTEIN SP38 ZONA PELLUCIDA-BINDING PROTEIN 2 MONDO|Ensembl=ENSMODG00000013995.4|UniProtKB=F6VRA6 F6VRA6 NBEAL2 PTHR13743:SF111 BEIGE/BEACH-RELATED NEUROBEACHIN-LIKE PROTEIN 2 anatomical structure formation involved in morphogenesis#GO:0048646;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;developmental process#GO:0032502;hemopoiesis#GO:0030097;cell development#GO:0048468;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000029616.2|UniProtKB=K7E4E8 K7E4E8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000038961.1|UniProtKB=A0A5F8GPS9 A0A5F8GPS9 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000007954.3|UniProtKB=F7EA12 F7EA12 MAP3K8 PTHR48016:SF31 MAP KINASE KINASE KINASE SSK2-RELATED-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 8 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Toll receptor signaling pathway#P00054>TPL2#P01364 MONDO|Ensembl=ENSMODG00000043726.1|UniProtKB=A0A5F8HE25 A0A5F8HE25 PROK2 PTHR18821:SF8 PROKINETICIN PROKINETICIN-2 endothelial cell proliferation#GO:0001935;epithelial cell proliferation#GO:0050673;cellular process#GO:0009987;cell population proliferation#GO:0008283 peptide hormone#PC00179 MONDO|Ensembl=ENSMODG00000007383.4|UniProtKB=F6ZMR3 F6ZMR3 WWC1 PTHR14791:SF22 BOMB/KIRA PROTEINS PROTEIN KIBRA protein binding#GO:0005515;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell migration#GO:0016477;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of developmental process#GO:0050793;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of biological process#GO:0050789;regulation of growth#GO:0040008;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000014196.4|UniProtKB=F6TRD1 F6TRD1 DRD2 PTHR24248:SF87 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(2) DOPAMINE RECEPTOR neurotransmitter receptor activity#GO:0030594;postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;G protein-coupled dopamine receptor signaling pathway#GO:0007212;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;negative regulation of cellular process#GO:0048523;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;adrenergic receptor signaling pathway#GO:0071875;negative regulation of cell communication#GO:0010648;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057 cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>DRD2#P06758;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Dopamine receptor mediated signaling pathway#P05912>D2/D3/D4#P05965;Nicotine pharmacodynamics pathway#P06587>DRD2/ DRD3/ DRD4#P06603;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 MONDO|Ensembl=ENSMODG00000001729.2|UniProtKB=F6X0B8 F6X0B8 LRIT1 PTHR45842:SF9 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEAT, IMMUNOGLOBULIN-LIKE DOMAIN AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000042004.1|UniProtKB=A0A5F8GBV0 A0A5F8GBV0 SLC25A27 PTHR45618:SF8 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL UNCOUPLING PROTEIN 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 response to temperature stimulus#GO:0009266;response to cold#GO:0009409;response to stimulus#GO:0050896;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000037188.1|UniProtKB=A0A5F8HEM7 A0A5F8HEM7 SEBOX PTHR47777:SF1 HOMEOBOX PROTEIN SEBOX HOMEOBOX PROTEIN SEBOX homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000008791.4|UniProtKB=F6RFK7 F6RFK7 ZNF496 PTHR23226:SF180 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 496 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000027531.2|UniProtKB=K7E2C9 K7E2C9 PTHR13382:SF87 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B BARD-RELATED cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000017811.5|UniProtKB=F6ZXZ9 F6ZXZ9 PYROXD1 PTHR43429:SF2 PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING TRNA LIGASE COMPLEX-ASSOCIATED NAD(P)H DEHYDROGENASE PYROXD1 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000028980.2|UniProtKB=K7E2M8 K7E2M8 NAF1 PTHR31633:SF1 H/ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1 H_ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 ribosome biogenesis#GO:0042254;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex assembly#GO:0022618;protein-RNA complex organization#GO:0071826;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;cellular component assembly#GO:0022607 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732 MONDO|Ensembl=ENSMODG00000023572.2|UniProtKB=F7G1G0 F7G1G0 HRK PTHR15056:SF0 ACTIVATOR OF APOPTOSIS HARAKIRI ACTIVATOR OF APOPTOSIS HARAKIRI positive regulation of apoptotic process#GO:0043065;positive regulation of organelle organization#GO:0010638;regulation of release of cytochrome c from mitochondria#GO:0090199;positive regulation of cellular component organization#GO:0051130;regulation of apoptotic process#GO:0042981;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;biological regulation#GO:0065007;regulation of programmed cell death#GO:0043067;regulation of mitochondrion organization#GO:0010821;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000047140.1|UniProtKB=A0A5F8G758 A0A5F8G758 LOC100028674 PTHR26454:SF152 OLFACTORY RECEPTOR OLFACTORY RECEPTOR OLFR212-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000051380.1|UniProtKB=A0A5F8HB66 A0A5F8HB66 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000018795.4|UniProtKB=F6ZN30 F6ZN30 PTHR15141:SF49 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 TFIIS N-TERMINAL DOMAIN-CONTAINING PROTEIN gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000004118.3|UniProtKB=F6VDU9 F6VDU9 NDUFA3 PTHR15221:SF0 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 3 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 3 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000003175.3|UniProtKB=F6VY90 F6VY90 GPR78 PTHR24245:SF7 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 78 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000020564.4|UniProtKB=F7AYL7 F7AYL7 NSUN7 PTHR14663:SF2 METHYLTRANSFERASE NSUN7-RELATED PROTEIN NSUN7 MONDO|Ensembl=ENSMODG00000013351.4|UniProtKB=F7GA66 F7GA66 FOXR1 PTHR46789:SF2 FORKHEAD BOX PROTEIN R1 FORKHEAD BOX PROTEIN R2 nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000045045.1|UniProtKB=A0A5F8GQ28 A0A5F8GQ28 PTHR13022:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 11 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT K translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 eukaryotic translation initiation factor 3 complex#GO:0005852;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000010838.3|UniProtKB=A0A5F8GEL4 A0A5F8GEL4 PTHR24073:SF263 DRAB5-RELATED RAB-LIKE PROTEIN 2A-RELATED hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000008512.4|UniProtKB=A0A5F8H680 A0A5F8H680 BPHL PTHR46331:SF2 VALACYCLOVIR HYDROLASE SERINE HYDROLASE BPHL serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000016862.4|UniProtKB=A0A5F8H8D5 A0A5F8H8D5 STXBP5 PTHR10241:SF22 LETHAL 2 GIANT LARVAE PROTEIN SYNTAXIN-BINDING PROTEIN 5 enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function activator activity#GO:0140677;syntaxin binding#GO:0019905;binding#GO:0005488;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;myosin binding#GO:0017022;SNARE binding#GO:0000149;enzyme activator activity#GO:0008047;cytoskeletal protein binding#GO:0008092 cellular localization#GO:0051641;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;exocytosis#GO:0006887;secretion by cell#GO:0032940;vesicle-mediated transport to the plasma membrane#GO:0098876;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;Golgi to plasma membrane transport#GO:0006893;export from cell#GO:0140352;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000036473.1|UniProtKB=A0A5F8HAW1 A0A5F8HAW1 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000016160.4|UniProtKB=F7CMD5 F7CMD5 IFT140 PTHR15722:SF7 IFT140/172-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 140 HOMOLOG cellular component organization#GO:0016043;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;cell projection organization#GO:0030030;microtubule-based transport#GO:0099111;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;intraciliary transport particle A#GO:0030991 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000005806.4|UniProtKB=F6XEJ5 F6XEJ5 PTHR10924:SF6 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED SOLUTE CARRIER FAMILY 49 MEMBER A3 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000010521.3|UniProtKB=F7DQK7 F7DQK7 ACTG2 PTHR11937:SF201 ACTIN ACTIN, GAMMA-ENTERIC SMOOTH MUSCLE structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 intracellular organelle#GO:0043229;extracellular region#GO:0005576;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 actin and actin related protein#PC00039 Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cadherin signaling pathway#P00012>F-actin#P00470;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Alzheimer disease-presenilin pathway#P00004>actin#P00114 MONDO|Ensembl=ENSMODG00000007774.4|UniProtKB=F7AWW5 F7AWW5 METTL9 PTHR12890:SF0 DREV PROTEIN PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000001277.3|UniProtKB=F7CIQ4 F7CIQ4 PTHR23113:SF26 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 5 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000044519.1|UniProtKB=A0A5F8GIG4 A0A5F8GIG4 OR51L1 PTHR26450:SF37 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51L1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009520.4|UniProtKB=F7EV18 F7EV18 ATP5MC3 PTHR10031:SF56 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, MITOCHONDRIAL transporter#PC00227;primary active transporter#PC00068;ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000038606.1|UniProtKB=A0A5F8H8G2 A0A5F8H8G2 PTHR24393:SF100 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 345-RELATED sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000045712.1|UniProtKB=A0A5F8GJB0 A0A5F8GJB0 SUMO1 PTHR10562:SF151 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 1 ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein sumoylation#GO:0016925;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;post-translational protein modification#GO:0043687 intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 p53 pathway#P00059>Sumo-1 ligase#P04635 MONDO|Ensembl=ENSMODG00000024019.3|UniProtKB=F7GHK2 F7GHK2 PTHR14309:SF7 EXPRESSED PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY B MEMBER 1 regulation of biological process#GO:0050789;regulation of cell differentiation#GO:0045595;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000002755.4|UniProtKB=F6YHC5 F6YHC5 TYR PTHR11474:SF124 TYROSINASE FAMILY MEMBER TYROSINASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 phenol-containing compound metabolic process#GO:0018958;cellular process#GO:0009987;phenol-containing compound biosynthetic process#GO:0046189;pigment metabolic process#GO:0042440;biosynthetic process#GO:0009058;pigment biosynthetic process#GO:0046148;metabolic process#GO:0008152;secondary metabolite biosynthetic process#GO:0044550;secondary metabolic process#GO:0019748;melanin biosynthetic process#GO:0042438 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;melanosome#GO:0042470;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000003007.3|UniProtKB=A0A5F8G2H6 A0A5F8G2H6 PTHR11046:SF0 OLIGORIBONUCLEASE, MITOCHONDRIAL OLIGORIBONUCLEASE, MITOCHONDRIAL 3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 endoribonuclease#PC00094;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000004389.4|UniProtKB=A0A5F8G6V1 A0A5F8G6V1 CYTIP PTHR15963:SF1 GENERAL RECEPTOR FOR PHOSPHOINOSITIDES 1-ASSOCIATED SCAFFOLD PROTEIN-RELATED CYTOHESIN-INTERACTING PROTEIN regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cell periphery#GO:0071944;cell cortex#GO:0005938 MONDO|Ensembl=ENSMODG00000027890.2|UniProtKB=K7E4W5 K7E4W5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013366.4|UniProtKB=F7DTL8 F7DTL8 P4HTM PTHR10869:SF249 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT TRANSMEMBRANE PROLYL 4-HYDROXYLASE regulation of myeloid cell differentiation#GO:0045637;regulation of cell differentiation#GO:0045595;regulation of hemopoiesis#GO:1903706;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of cell development#GO:0060284;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of multicellular organismal process#GO:0051239 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000009171.4|UniProtKB=F7ADI1 F7ADI1 PRPSAP1 PTHR10210:SF28 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE-ASSOCIATED PROTEIN 1 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164 catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000040040.1|UniProtKB=A0A5F8GWZ7 A0A5F8GWZ7 PTHR11216:SF127 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;protein localization to cell periphery#GO:1990778;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;organelle assembly#GO:0070925;endocytosis#GO:0006897;cell projection organization#GO:0030030;endocytic recycling#GO:0032456;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657 cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;recycling endosome#GO:0055037;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;early endosome#GO:0005769 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000043226.1|UniProtKB=A0A5F8HE72 A0A5F8HE72 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013942.4|UniProtKB=F6SBT9 F6SBT9 TGM6 PTHR11590:SF50 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 6 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 cellular process#GO:0009987;skin development#GO:0043588;cell differentiation#GO:0030154;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;developmental process#GO:0032502;epidermis development#GO:0008544;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;animal organ development#GO:0048513 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220 MONDO|Ensembl=ENSMODG00000003904.4|UniProtKB=A0A5F8GSU0 A0A5F8GSU0 RNF130 PTHR22765:SF40 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF130 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;cell death#GO:0008219;programmed cell death#GO:0012501 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000009997.4|UniProtKB=A0A5F8GU04 A0A5F8GU04 APIP PTHR10640:SF7 METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;carbohydrate derivative metabolic process#GO:1901135 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 MONDO|Ensembl=ENSMODG00000023400.2|UniProtKB=F6T8Z3 F6T8Z3 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000017780.4|UniProtKB=A0A5F8GA01 A0A5F8GA01 MAN1A1 PTHR11742:SF31 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IA catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000047634.1|UniProtKB=A0A5F8GE13 A0A5F8GE13 BTN1A1 PTHR24100:SF139 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;immune system process#GO:0002376;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000012558.4|UniProtKB=F6PLP2 F6PLP2 UTP18 PTHR18359:SF0 WD-REPEAT PROTEIN-RELATED U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 18 HOMOLOG nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;90S preribosome#GO:0030686;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000015293.4|UniProtKB=A0A5F8GP27 A0A5F8GP27 BRD10 PTHR31095:SF3 RIKEN CDNA 9930021J03 GENE BROMODOMAIN CONTAINING 10 MONDO|Ensembl=ENSMODG00000047016.1|UniProtKB=A0A5F8G4D7 A0A5F8G4D7 PTHR47740:SF1 LCK-INTERACTING TRANSMEMBRANE ADAPTER 1, LIME1 LCK-INTERACTING TRANSMEMBRANE ADAPTER 1 protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900 regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;immune system process#GO:0002376;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;antigen receptor-mediated signaling pathway#GO:0050851;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;B cell receptor signaling pathway#GO:0050853;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;immune response-activating signaling pathway#GO:0002757;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of immune response#GO:0050778 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014743.4|UniProtKB=F6YNA3 F6YNA3 CNMD PTHR14064:SF6 CHONDROMODULIN-RELATED LEUKOCYTE CELL-DERIVED CHEMOTAXIN 1 regulation of vasculature development#GO:1901342;negative regulation of cellular process#GO:0048523;regulation of angiogenesis#GO:0045765;regulation of anatomical structure morphogenesis#GO:0022603;negative regulation of angiogenesis#GO:0016525;regulation of cell population proliferation#GO:0042127;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of cell population proliferation#GO:0008285;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794 MONDO|Ensembl=ENSMODG00000000735.4|UniProtKB=A0A5F8HHU7 A0A5F8HHU7 PREPL PTHR11757:SF23 PROTEASE FAMILY S9A OLIGOPEPTIDASE PROLYL ENDOPEPTIDASE-LIKE cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;retrograde transport, endosome to Golgi#GO:0042147;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;protein localization to cell periphery#GO:1990778;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;Golgi to plasma membrane protein transport#GO:0043001;cytosolic transport#GO:0016482;Golgi to plasma membrane transport#GO:0006893;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;localization#GO:0051179 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 serine protease#PC00203 Vasopressin synthesis#P04395>Endo Peptidase#P04596 MONDO|Ensembl=ENSMODG00000025150.2|UniProtKB=F7CKX7 F7CKX7 PTHR11208:SF30 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 1 RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;binding#GO:0005488;poly(A) binding#GO:0008143;mRNA binding#GO:0003729 regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000014952.4|UniProtKB=F6VDH5 F6VDH5 COG3 PTHR13302:SF8 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;retrograde transport, vesicle recycling within Golgi#GO:0000301;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;COG complex#GO:0017119;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000046269.1|UniProtKB=A0A5F8GX68 A0A5F8GX68 PTHR10338:SF119 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H4 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000047950.1|UniProtKB=K7DZW2 K7DZW2 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000003500.4|UniProtKB=F7C8M7 F7C8M7 PTHR15172:SF1 GALACTOCEREBROSIDASE GALACTOCEREBROSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;ceramide metabolic process#GO:0006672 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;lysosome#GO:0005764;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;galactosidase#PC00104 MONDO|Ensembl=ENSMODG00000047728.1|UniProtKB=A0A5F8GJG9 A0A5F8GJG9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000020046.3|UniProtKB=F6X339 F6X339 PTHR24384:SF261 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 719 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000017610.3|UniProtKB=F6VAX3 F6VAX3 PPP1R26 PTHR15724:SF0 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 26 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 26 phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000002035.4|UniProtKB=F6QW83 F6QW83 ZHX1 PTHR15467:SF4 ZINC-FINGERS AND HOMEOBOXES RELATED ZINC FINGERS AND HOMEOBOXES PROTEIN 1 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000002215.3|UniProtKB=F7G3B7 F7G3B7 PTHR42918:SF16 LYSYL-TRNA SYNTHETASE LYSINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;ligase activity#GO:0016874;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA binding#GO:0003723;tRNA binding#GO:0000049;catalytic activity, acting on a tRNA#GO:0140101;nucleic acid binding#GO:0003676;binding#GO:0005488;adenylyltransferase activity#GO:0070566 leukocyte activation#GO:0045321;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cell activation#GO:0001775;translation#GO:0006412;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;macromolecule biosynthetic process#GO:0009059;organophosphate metabolic process#GO:0019637;tRNA aminoacylation#GO:0043039;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;amino acid metabolic process#GO:0006520;positive regulation of cell activation#GO:0050867;multicellular organismal process#GO:0032501;nucleoside phosphate biosynthetic process#GO:1901293;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of leukocyte activation#GO:0002694;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;protein biosynthetic process#GO:0160307;immune system process#GO:0002376;nucleotide biosynthetic process#GO:0009165;cell activation involved in immune response#GO:0002263;nucleotide metabolic process#GO:0009117;RNA metabolic process#GO:0016070;tRNA aminoacylation for protein translation#GO:0006418;regulation of macrophage activation#GO:0043030;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;myeloid leukocyte activation#GO:0002274;gene expression#GO:0010467;immune effector process#GO:0002252;leukocyte activation involved in immune response#GO:0002366;positive regulation of leukocyte activation#GO:0002696;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrion#GO:0005739;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000024509.3|UniProtKB=F7AL73 F7AL73 OR4K1 PTHR48002:SF9 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000050122.1|UniProtKB=A0A5F8G5J7 A0A5F8G5J7 HPGD PTHR44229:SF10 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 icosanoid metabolic process#GO:0006690;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;lipid metabolic process#GO:0006629;prostaglandin metabolic process#GO:0006693;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;extracellular region#GO:0005576 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000005276.3|UniProtKB=A0A5F8G5Z7 A0A5F8G5Z7 NFATC3 PTHR12533:SF6 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;intracellular signaling cassette#GO:0141124;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;calcium-mediated signaling#GO:0019722;calcineurin-mediated signaling#GO:0097720;calcineurin-NFAT signaling cascade#GO:0033173;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851;Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;B cell activation#P00010>NFAT#P00367;T cell activation#P00053>NFAT#P01294;Axon guidance mediated by netrin#P00009>NFAT#P00359;Wnt signaling pathway#P00057>NFAT#P01452 MONDO|Ensembl=ENSMODG00000018565.3|UniProtKB=F7FRS1 F7FRS1 MRAS PTHR24070:SF268 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN M-RAS hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265;establishment or maintenance of cell polarity#GO:0007163 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 EGF receptor signaling pathway#P00018>Ras#P00552 MONDO|Ensembl=ENSMODG00000044244.1|UniProtKB=F6T8Y7 F6T8Y7 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000023546.1|UniProtKB=F7C9V7 F7C9V7 LOC100016966 PTHR48001:SF125 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1B1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012889.4|UniProtKB=F6Z1A1 F6Z1A1 CAMSAP2 PTHR21595:SF1 PATRONIN CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 2 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 regulation of protein depolymerization#GO:1901879;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of protein depolymerization#GO:1901880;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;supramolecular fiber organization#GO:0097435;negative regulation of cytoskeleton organization#GO:0051494;microtubule cytoskeleton organization#GO:0000226;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of microtubule-based process#GO:0032886;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component organization#GO:0051128;cytoplasmic microtubule organization#GO:0031122;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;cellular component organization#GO:0016043;negative regulation of organelle organization#GO:0010639 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;microtubule end#GO:1990752;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000014874.3|UniProtKB=F6YKW6 F6YKW6 KIF2B PTHR24115:SF524 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF2B cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000009677.4|UniProtKB=A0A5F8GN07 A0A5F8GN07 NPM2 PTHR22747:SF14 NUCLEOPLASMIN NUCLEOPLASMIN-2 binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;histone binding#GO:0042393;RNA binding#GO:0003723;protein binding#GO:0005515 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000015564.4|UniProtKB=F7AJ98 F7AJ98 TUFM PTHR43721:SF36 ELONGATION FACTOR TU-RELATED ELONGATION FACTOR TU, MITOCHONDRIAL translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translation elongation factor#PC00222 MONDO|Ensembl=ENSMODG00000016551.4|UniProtKB=F7DNT3 F7DNT3 BHLHE41 PTHR10985:SF76 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 41 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;negative regulation of biological process#GO:0048519;circadian regulation of gene expression#GO:0032922;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;rhythmic process#GO:0048511;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000048750.1|UniProtKB=A0A5F8G7M5 A0A5F8G7M5 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000010896.4|UniProtKB=A0A5F8H8Z6 A0A5F8H8Z6 PTHR14885:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43 developmental process#GO:0032502;spermatogenesis#GO:0007283;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025 MONDO|Ensembl=ENSMODG00000041915.1|UniProtKB=K7E3J2 K7E3J2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000024138.3|UniProtKB=F6UKP4 F6UKP4 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000047692.1|UniProtKB=A0A5F8G2Y1 A0A5F8G2Y1 SGMS2 PTHR21290:SF24 SPHINGOMYELIN SYNTHETASE PHOSPHATIDYLCHOLINE:CERAMIDE CHOLINEPHOSPHOTRANSFERASE 2 phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;ceramide metabolic process#GO:0006672;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;sphingomyelin metabolic process#GO:0006684;biosynthetic process#GO:0009058;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513 cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000042957.1|UniProtKB=F7E0M1 F7E0M1 LOC100023593 PTHR48018:SF28 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8K3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000041737.1|UniProtKB=A0A5F8GQP4 A0A5F8GQP4 PTHR11387:SF12 CYTOCHROME C OXIDASE SUBUNIT 6B CYTOCHROME C OXIDASE SUBUNIT 6B2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidase#PC00175;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000003801.4|UniProtKB=F6ZK16 F6ZK16 PTHR23003:SF6 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN M RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nuclear mRNA surveillance#GO:0071028;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000012288.4|UniProtKB=A0A5F8GUK1 A0A5F8GUK1 NUDT19 PTHR12318:SF0 TESTOSTERONE-REGULATED PROTEIN RP2 ACYL-COENZYME A DIPHOSPHATASE NUDT19 MONDO|Ensembl=ENSMODG00000050141.1|UniProtKB=A0A5F8HI91 A0A5F8HI91 WDR47 PTHR19863:SF5 NEMITIN (NEURONAL ENRICHED MAP INTERACTING PROTEIN) HOMOLOG WD REPEAT-CONTAINING PROTEIN 47 MONDO|Ensembl=ENSMODG00000001854.3|UniProtKB=F6SP09 F6SP09 TK1 PTHR11441:SF0 THYMIDINE KINASE THYMIDINE KINASE, CYTOSOLIC transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;deoxynucleoside kinase activity#GO:0019136 cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;small molecule metabolic process#GO:0044281;nucleoside monophosphate biosynthetic process#GO:0009124;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117 kinase#PC00137;nucleotide kinase#PC00172 Salvage pyrimidine deoxyribonucleotides#P02774>Deoxyuridine kinase#P03146;Salvage pyrimidine deoxyribonucleotides#P02774>Thymidine kinase#P03147 MONDO|Ensembl=ENSMODG00000013936.3|UniProtKB=F6SCM4 F6SCM4 PTHR24256:SF246 TRYPTASE-RELATED SERINE PROTEASE 42-RELATED catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000019911.4|UniProtKB=F6VQ52 F6VQ52 PTHR23073:SF7 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6A isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 proteasome complex#GO:0000502;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000044658.1|UniProtKB=A0A5F8G8I4 A0A5F8G8I4 LOC100025940 PTHR48018:SF58 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 9I1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006894.2|UniProtKB=F6PV47 F6PV47 LOC100010121 PTHR46359:SF3 GEO07743P1 RING FINGER PROTEIN 11 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535 MONDO|Ensembl=ENSMODG00000004703.3|UniProtKB=F6TQ50 F6TQ50 OAZ1 PTHR10279:SF8 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME 1 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000000326.3|UniProtKB=F6VU77 F6VU77 GTPBP6 PTHR10229:SF0 GTP-BINDING PROTEIN HFLX GTP-BINDING PROTEIN 6-RELATED ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000002466.3|UniProtKB=F7DDQ2 F7DDQ2 COPS2 PTHR10678:SF3 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 COP9 SIGNALOSOME COMPLEX SUBUNIT 2 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 post-translational protein modification#GO:0043687;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000016119.3|UniProtKB=F7EAL9 F7EAL9 NUBP2 PTHR23264:SF19 NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2 binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000012865.3|UniProtKB=F7C946 F7C946 MIEN1 PTHR15124:SF27 SELENOPROTEIN W MIGRATION AND INVASION ENHANCER 1 negative regulation of apoptotic process#GO:0043066;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;negative regulation of programmed cell death#GO:0043069;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of filopodium assembly#GO:0051489;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cell projection assembly#GO:0060491;positive regulation of cellular component organization#GO:0051130;positive regulation of cell projection organization#GO:0031346 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000016793.3|UniProtKB=A0A5F8GQ45 A0A5F8GQ45 HAGHL PTHR11935:SF77 BETA LACTAMASE DOMAIN HYDROXYACYLGLUTATHIONE HYDROLASE-LIKE PROTEIN thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 MONDO|Ensembl=ENSMODG00000020088.4|UniProtKB=F7ESR4 F7ESR4 SSRP1 PTHR45849:SF7 FACT COMPLEX SUBUNIT SSRP1 FACT COMPLEX SUBUNIT SSRP1 histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 regulation of biological process#GO:0050789;regulation of chromatin organization#GO:1902275;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000048213.1|UniProtKB=A0A5F8H2Y3 A0A5F8H2Y3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012009.2|UniProtKB=F7AMI2 F7AMI2 SSTR1 PTHR24229:SF38 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 1 binding#GO:0005488;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;biological regulation#GO:0065007;response to estradiol#GO:0032355;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 MONDO|Ensembl=ENSMODG00000007626.3|UniProtKB=F7BLA4 F7BLA4 SLC41A3 PTHR16228:SF22 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SOLUTE CARRIER FAMILY 41 MEMBER 3 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000007949.4|UniProtKB=F7G8U4 F7G8U4 MGLL PTHR11614:SF198 PHOSPHOLIPASE-RELATED MONOGLYCERIDE LIPASE hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 membrane#GO:0016020;cellular anatomical structure#GO:0110165 phospholipase#PC00186;lipase#PC00143 MONDO|Ensembl=ENSMODG00000018208.4|UniProtKB=F6PGW3 F6PGW3 CFAP91 PTHR22455:SF10 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91 MONDO|Ensembl=ENSMODG00000013802.4|UniProtKB=F6TDB8 F6TDB8 APOA4 PTHR18976:SF1 APOLIPOPROTEIN APOLIPOPROTEIN A-IV sterol transfer activity#GO:0120015;transporter activity#GO:0005215;phospholipid binding#GO:0005543;enzyme activator activity#GO:0008047;cholesterol transfer activity#GO:0120020;molecular function regulator activity#GO:0098772;binding#GO:0005488;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;molecular function activator activity#GO:0140677;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;enzyme regulator activity#GO:0030234 macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;cholesterol efflux#GO:0033344;cellular process#GO:0009987;lipid transport#GO:0006869;phospholipid transport#GO:0015914;steroid metabolic process#GO:0008202;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;transport#GO:0006810;chemical homeostasis#GO:0048878;sterol metabolic process#GO:0016125;establishment of localization#GO:0051234;sterol transport#GO:0015918;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;small molecule metabolic process#GO:0044281;organophosphate ester transport#GO:0015748;homeostatic process#GO:0042592;secondary alcohol metabolic process#GO:1902652;lipid localization#GO:0010876;localization#GO:0051179;organic hydroxy compound transport#GO:0015850 very-low-density lipoprotein particle#GO:0034361;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;lipoprotein particle#GO:1990777;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;protein-lipid complex#GO:0032994;high-density lipoprotein particle#GO:0034364;plasma lipoprotein particle#GO:0034358;membrane-bounded organelle#GO:0043227 transfer/carrier protein#PC00219;apolipoprotein#PC00052 MONDO|Ensembl=ENSMODG00000000359.5|UniProtKB=A0A5F8HJK8 A0A5F8HJK8 FHOD3 PTHR45920:SF3 FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I FH1_FH2 DOMAIN-CONTAINING PROTEIN 3 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cardiac muscle cell differentiation#GO:0055007;cellular component assembly#GO:0022607;heart development#GO:0007507;positive regulation of cellular component biogenesis#GO:0044089;striated muscle tissue development#GO:0014706;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of actin filament bundle assembly#GO:0032231;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;actomyosin structure organization#GO:0031032;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;circulatory system development#GO:0072359;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;positive regulation of organelle organization#GO:0010638;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;tissue development#GO:0009888;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;positive regulation of actin filament bundle assembly#GO:0032233;actin filament organization#GO:0007015;cellular developmental process#GO:0048869;cardiac muscle tissue development#GO:0048738;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;regulation of supramolecular fiber organization#GO:1902903;muscle cell development#GO:0055001;regulation of stress fiber assembly#GO:0051492;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;supramolecular fiber organization#GO:0097435;system development#GO:0048731;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000044323.1|UniProtKB=A0A5F8GTZ3 A0A5F8GTZ3 MYH8 PTHR45615:SF35 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-8 cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;actin filament binding#GO:0051015;ATP-dependent activity#GO:0140657;actin binding#GO:0003779 system process#GO:0003008;multicellular organismal process#GO:0032501;muscle contraction#GO:0006936;muscle system process#GO:0003012 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867 MONDO|Ensembl=ENSMODG00000020813.3|UniProtKB=F7G0J8 F7G0J8 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000009421.4|UniProtKB=F7BLG7 F7BLG7 BBOX1 PTHR10696:SF33 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED GAMMA-BUTYROBETAINE DIOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;carnitine metabolic process#GO:0009437;cellular process#GO:0009987;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 hydroxylase#PC00122;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000019806.4|UniProtKB=F6SUA0 F6SUA0 GARNL3 PTHR15711:SF62 RAP GTPASE-ACTIVATING PROTEIN GTPASE-ACTIVATING RAP_RAN-GAP DOMAIN-LIKE PROTEIN 3 GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;G-protein modulator#PC00022 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1GAP#P00737 MONDO|Ensembl=ENSMODG00000016859.4|UniProtKB=A0A5F8H8B1 A0A5F8H8B1 LOC100021259 PTHR23412:SF15 STEREOCILIN RELATED MESOTHELIN-LIKE PROTEIN cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000049572.1|UniProtKB=A0A5F8GEK5 A0A5F8GEK5 PTHR23304:SF189 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000001593.4|UniProtKB=A0A5F8G8Z6 A0A5F8G8Z6 CHAC2 PTHR12192:SF2 CATION TRANSPORT PROTEIN CHAC-RELATED GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 2 MONDO|Ensembl=ENSMODG00000008847.4|UniProtKB=F7CUN0 F7CUN0 SLC25A12 PTHR45678:SF7 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED ELECTROGENIC ASPARTATE_GLUTAMATE ANTIPORTER SLC25A12, MITOCHONDRIAL carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 localization#GO:0051179;amino acid transmembrane transport#GO:0003333;pyridine-containing compound metabolic process#GO:0072524;L-glutamate import#GO:0051938;carboxylic acid transmembrane transport#GO:1905039;nucleoside phosphate metabolic process#GO:0006753;L-alpha-amino acid transmembrane transport#GO:1902475;primary metabolic process#GO:0044238;establishment of localization#GO:0051234;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;nucleobase-containing compound metabolic process#GO:0006139;dicarboxylic acid transport#GO:0006835;aspartate transmembrane transport#GO:0015810;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;nucleotide metabolic process#GO:0009117;transmembrane transport#GO:0055085;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;acidic amino acid transport#GO:0015800;metabolic process#GO:0008152;L-glutamate transmembrane transport#GO:0015813;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000041326.1|UniProtKB=F7CBA2 F7CBA2 LOC100010284 PTHR26453:SF9 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10A4 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006494.4|UniProtKB=F7EKN9 F7EKN9 STX6 PTHR19957:SF104 SYNTAXIN SYNTAXIN-6 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;cytosolic transport#GO:0016482;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;organelle organization#GO:0006996;retrograde transport, endosome to Golgi#GO:0042147;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054;cytoplasm#GO:0005737;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;presynapse#GO:0098793;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;SNARE complex#GO:0031201;synapse#GO:0045202;cellular anatomical structure#GO:0110165;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796 SNARE protein#PC00034 Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074 MONDO|Ensembl=ENSMODG00000015716.4|UniProtKB=A0A5F8HD56 A0A5F8HD56 CCDC112 PTHR21549:SF0 MUTATED IN BLADDER CANCER 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 112 MONDO|Ensembl=ENSMODG00000024572.2|UniProtKB=F7BTC7 F7BTC7 LOC100017233 PTHR11984:SF56 CONNEXIN GAP JUNCTION GAMMA-3 PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267 cellular process#GO:0009987;regulation of biological process#GO:0050789;cell communication#GO:0007154;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911 cell junction protein#PC00070;gap junction#PC00105 MONDO|Ensembl=ENSMODG00000036851.1|UniProtKB=A0A5F8GWY8 A0A5F8GWY8 PTHR12153:SF18 SELENOPROTEIN O SELENOPROTEIN O MONDO|Ensembl=ENSMODG00000012465.3|UniProtKB=F6Q4R4 F6Q4R4 PTHR23426:SF70 FERREDOXIN/ADRENODOXIN 2FE-2S FERREDOXIN-TYPE DOMAIN-CONTAINING PROTEIN generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;metabolic process#GO:0008152;electron transport chain#GO:0022900 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000013541.4|UniProtKB=A0A5F8GYV3 A0A5F8GYV3 TNFAIP8 PTHR12757:SF3 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Huntington disease#P00029>FIP-2#P00772 MONDO|Ensembl=ENSMODG00000008789.4|UniProtKB=A0A5F8GVY5 A0A5F8GVY5 FAM120A PTHR15976:SF14 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA CONSTITUTIVE COACTIVATOR OF PPAR-GAMMA-LIKE PROTEIN 1 MONDO|Ensembl=ENSMODG00000046750.1|UniProtKB=F7B7S9 F7B7S9 monDomV1R1281 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007851.4|UniProtKB=F7ET75 F7ET75 ZKSCAN5 PTHR24377:SF214 IP01015P-RELATED ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000043534.1|UniProtKB=A0A5F8G569 A0A5F8G569 PTHR22692:SF34 MYOSIN VII, XV MYOSIN VIIA actin binding motor protein#PC00040 MONDO|Ensembl=ENSMODG00000001675.4|UniProtKB=F6ZU10 F6ZU10 PTHR47060:SF1 HOMEOBOX PROTEIN NOBOX HOMEOBOX PROTEIN NOBOX homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000007607.3|UniProtKB=A0A5F8G888 A0A5F8G888 TMEM64 PTHR46593:SF1 TRANSMEMBRANE PROTEIN 64 TRANSMEMBRANE PROTEIN 64 biological regulation#GO:0065007;regulation of bone remodeling#GO:0046850;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;positive regulation of myeloid cell differentiation#GO:0045639;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;regulation of cell differentiation#GO:0045595;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;positive regulation of developmental process#GO:0051094;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;regulation of developmental process#GO:0050793;regulation of cytosolic calcium ion concentration#GO:0051480;regulation of hemopoiesis#GO:1903706;regulation of tissue remodeling#GO:0034103;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;monoatomic ion homeostasis#GO:0050801;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;intracellular calcium ion homeostasis#GO:0006874;positive regulation of cell differentiation#GO:0045597;chemical homeostasis#GO:0048878;intracellular monoatomic ion homeostasis#GO:0006873;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;calcium ion homeostasis#GO:0055074;regulation of myeloid cell differentiation#GO:0045637;inorganic ion homeostasis#GO:0098771;regulation of bone resorption#GO:0045124 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000040322.1|UniProtKB=A0A5F8GW49 A0A5F8GW49 LOC100025368 PTHR26454:SF43 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000051222.1|UniProtKB=A0A5F8GN78 A0A5F8GN78 PTHR34141:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000018148.3|UniProtKB=F7CWU5 F7CWU5 USP5 PTHR24006:SF655 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 5 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000011279.4|UniProtKB=A0A5F8HIT7 A0A5F8HIT7 MROH6 PTHR23120:SF40 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 6 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000044097.1|UniProtKB=A0A5F8G930 A0A5F8G930 PTHR24377:SF975 IP01015P-RELATED ZINC FINGER PROTEIN 883-LIKE transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009622.4|UniProtKB=F6REQ9 F6REQ9 RNF185 PTHR12313:SF13 E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF185 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000020730.4|UniProtKB=F7ANR2 F7ANR2 EPHA5 PTHR46877:SF13 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 5 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon guidance#GO:0007411;axon development#GO:0061564;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794 dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000044983.1|UniProtKB=A0A5F8H595 A0A5F8H595 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000020749.4|UniProtKB=F6ZZG1 F6ZZG1 PTHR24253:SF47 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 11G peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000029167.2|UniProtKB=K7DYQ4 K7DYQ4 RNF148 PTHR22765:SF53 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING RING FINGER PROTEIN 148 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 Golgi apparatus#GO:0005794;endosome#GO:0005768;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;late endosome#GO:0005770;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000008258.4|UniProtKB=F6Z8S5 F6Z8S5 PTHR10796:SF60 PATCHED-RELATED PATCHED DOMAIN-CONTAINING PROTEIN 3 cellular anatomical structure#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000024536.3|UniProtKB=F7FTK5 F7FTK5 PTHR23427:SF13 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 4 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization#GO:0016043;organelle organization#GO:0006996 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000040194.1|UniProtKB=F7DG67 F7DG67 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007727.4|UniProtKB=F7EUF6 F7EUF6 GABRA1 PTHR18945:SF514 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;signaling#GO:0023052;synapse assembly#GO:0007416;animal gross anatomical part developmental process#GO:0160108;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;nervous system development#GO:0007399;cellular component assembly#GO:0022607;monoatomic anion transmembrane transport#GO:0098656;chloride transport#GO:0006821;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;system development#GO:0048731;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;localization#GO:0051179;anatomical structure development#GO:0048856;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;developmental process#GO:0032502;transport#GO:0006810;establishment of localization#GO:0051234 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794;cell projection membrane#GO:0031253;dendrite#GO:0030425;leading edge membrane#GO:0031256;dendritic tree#GO:0097447;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell junction#GO:0030054;signaling receptor complex#GO:0043235;neuron projection membrane#GO:0032589 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000020725.4|UniProtKB=F7ANU1 F7ANU1 PKD2 PTHR10877:SF114 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-2 transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated sodium channel activity#GO:0005248;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;binding#GO:0005488;gated channel activity#GO:0022836;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;voltage-gated channel activity#GO:0022832;protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;passive transmembrane transporter activity#GO:0022803;sodium channel activity#GO:0005272;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;signaling receptor binding#GO:0005102;small molecule binding#GO:0036094;ion binding#GO:0043167;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;cation binding#GO:0043169 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;detection of stimulus#GO:0051606;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;response to mechanical stimulus#GO:0009612;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;response to external stimulus#GO:0009605;detection of mechanical stimulus#GO:0050982;transport#GO:0006810;response to stimulus#GO:0050896;metal ion transport#GO:0030001;response to abiotic stimulus#GO:0009628;calcium ion transmembrane transport#GO:0070588;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000001102.4|UniProtKB=A0A5F8H212 A0A5F8H212 CC2D2A PTHR20837:SF7 CENTROSOMAL PROTEIN-RELATED COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 2A protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;protein localization to cilium#GO:0061512;cilium assembly#GO:0060271;cellular component organization#GO:0016043;non-motile cilium assembly#GO:1905515;localization#GO:0051179;cilium organization#GO:0044782;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031 plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 MONDO|Ensembl=ENSMODG00000046170.1|UniProtKB=A0A5F8H734 A0A5F8H734 PTHR12466:SF8 CDC73 DOMAIN PROTEIN PARAFIBROMIN RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000019273.4|UniProtKB=A0A5F8H9X1 A0A5F8H9X1 GRID2 PTHR18966:SF109 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2 molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789 cell junction#GO:0030054;transporter complex#GO:1990351;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;neuron projection#GO:0043005;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;cell projection#GO:0042995;neuron spine#GO:0044309;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;dendritic spine#GO:0043197;postsynapse#GO:0098794;signaling receptor complex#GO:0043235;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;membrane#GO:0016020;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;asymmetric synapse#GO:0032279;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000041242.1|UniProtKB=A0A5F8GYF5 A0A5F8GYF5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000019514.4|UniProtKB=A0A5F8HFT1 A0A5F8HFT1 TBC1D20 PTHR20913:SF10 TBC1 DOMAIN FAMILY MEMBER 20/GTPASE TBC1 DOMAIN FAMILY MEMBER 20 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;Golgi organization#GO:0007030;cellular component organization#GO:0016043;organelle organization#GO:0006996 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000039859.1|UniProtKB=A0A5F8GMD0 A0A5F8GMD0 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000047770.1|UniProtKB=A0A5F8HDJ8 A0A5F8HDJ8 PTHR26450:SF69 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56B1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017171.3|UniProtKB=A0A5F8GW67 A0A5F8GW67 P3H1 PTHR14049:SF5 LEPRECAN 1 PROLYL 3-HYDROXYLASE 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 extracellular matrix glycoprotein#PC00100 MONDO|Ensembl=ENSMODG00000042226.1|UniProtKB=A0A5F8HIR2 A0A5F8HIR2 LOC100014107 PTHR48001:SF39 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004053.3|UniProtKB=F7C3B8 F7C3B8 PTHR28637:SF1 DNA REPLICATION FACTOR CDT1 DNA REPLICATION FACTOR CDT1 protein binding#GO:0005515;DNA binding#GO:0003677;enzyme binding#GO:0019899;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of biological process#GO:0048519;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;signaling#GO:0023052;cell communication#GO:0007154;regulation of DNA replication#GO:0006275;intracellular signal transduction#GO:0035556;regulation of primary metabolic process#GO:0080090;DNA integrity checkpoint signaling#GO:0031570;regulation of metabolic process#GO:0019222;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell cycle checkpoint signaling#GO:0000075;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of DNA-templated DNA replication initiation#GO:0030174;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;negative regulation of cell cycle#GO:0045786;DNA replication checkpoint signaling#GO:0000076 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000005125.4|UniProtKB=F7F5P8 F7F5P8 CDHR2 PTHR24028:SF314 CADHERIN-87A CADHERIN-RELATED FAMILY MEMBER 2 cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 MONDO|Ensembl=ENSMODG00000028821.2|UniProtKB=K7E556 K7E556 PTHR32430:SF1 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 8 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 8 MONDO|Ensembl=ENSMODG00000005761.4|UniProtKB=F6QDA0 F6QDA0 S1PR5 PTHR22750:SF20 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 5 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000013302.3|UniProtKB=F6ZJA5 F6ZJA5 HSP90AA1 PTHR11528:SF87 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-ALPHA carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP binding#GO:0005524;binding#GO:0005488;ATP-dependent activity#GO:0140657;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887 protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;protein folding#GO:0006457;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;protein stabilization#GO:0050821;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;biological regulation#GO:0065007;response to stress#GO:0006950;response to heat#GO:0009408;cellular response to heat#GO:0034605;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of protein stability#GO:0031647 cytosol#GO:0005829;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;myelin sheath#GO:0043209;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;cell body#GO:0044297;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Hsp90 family chaperone#PC00028;chaperone#PC00072 MONDO|Ensembl=ENSMODG00000008530.3|UniProtKB=F7DHD5 F7DHD5 PIK3R5 PTHR15593:SF2 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 5 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052 catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898;membrane protein complex#GO:0098796;membrane#GO:0016020;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;EGF receptor signaling pathway#P00018>PI3K#P00557;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;PDGF signaling pathway#P00047>PI3K#P01168;p53 pathway feedback loops 2#P04398>PI3K#P04661;PI3 kinase pathway#P00048>p101#P01203;Axon guidance mediated by netrin#P00009>PI3K#P00363 MONDO|Ensembl=ENSMODG00000010502.4|UniProtKB=F7EAC5 F7EAC5 MAF1 PTHR22504:SF0 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 HOMOLOG RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;binding#GO:0005488 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000047503.1|UniProtKB=A0A5F8HGC5 A0A5F8HGC5 PTHR26453:SF0 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13D1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021090.4|UniProtKB=F6UIX5 F6UIX5 EFHC2 PTHR12086:SF11 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING FAMILY MEMBER C2 cell junction assembly#GO:0034329;regulation of dendrite morphogenesis#GO:0048814;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;cell junction organization#GO:0034330;regulation of dendrite development#GO:0050773;synapse assembly#GO:0007416;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;anatomical structure development#GO:0048856;system development#GO:0048731;cellular component biogenesis#GO:0044085;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of cell projection organization#GO:0031344;developmental process#GO:0032502;growth#GO:0040007;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;multicellular organism development#GO:0007275;regulation of anatomical structure morphogenesis#GO:0022603;developmental growth#GO:0048589;neuromuscular junction development#GO:0007528 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;cytoplasmic microtubule#GO:0005881;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000045066.1|UniProtKB=A0A5F8GQX6 A0A5F8GQX6 LOC103093918 PTHR16675:SF67 MHC CLASS I-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000018512.3|UniProtKB=F7A4K5 F7A4K5 PTHR24383:SF20 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 44 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000049014.1|UniProtKB=A0A5F8GVW5 A0A5F8GVW5 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000049964.1|UniProtKB=A0A5F8GU88 A0A5F8GU88 ELOVL2 PTHR11157:SF16 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000004965.4|UniProtKB=A0A5F8H455 A0A5F8H455 ENTPD1 PTHR11782:SF32 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 metabolic process#GO:0008152;nucleoside diphosphate metabolic process#GO:0009132;organophosphate catabolic process#GO:0046434;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleoside diphosphate catabolic process#GO:0009134;cellular process#GO:0009987;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121;nucleotide phosphatase#PC00173 MONDO|Ensembl=ENSMODG00000043163.1|UniProtKB=A0A5F8G2Y8 A0A5F8G2Y8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000021344.3|UniProtKB=F7FSM7 F7FSM7 PTHR10880:SF48 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000008260.4|UniProtKB=A0A5F8HDN7 A0A5F8HDN7 GMDS PTHR43715:SF1 GDP-MANNOSE 4,6-DEHYDRATASE GDP-MANNOSE 4,6 DEHYDRATASE lyase#PC00144;dehydratase#PC00091 Mannose metabolism#P02752>GDP-Mannose 4,6-dehydratase#P03015 MONDO|Ensembl=ENSMODG00000024583.4|UniProtKB=F7B6A1 F7B6A1 SKOR1 PTHR10005:SF8 SKI ONCOGENE-RELATED SKI FAMILY TRANSCRIPTIONAL COREPRESSOR 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of signal transduction#GO:0009968;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of BMP signaling pathway#GO:0030514;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of BMP signaling pathway#GO:0030510;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 MONDO|Ensembl=ENSMODG00000007212.4|UniProtKB=F6WSR6 F6WSR6 YJEFN3 PTHR13232:SF12 NAD(P)H-HYDRATE EPIMERASE YJEF N-TERMINAL DOMAIN-CONTAINING PROTEIN 3 racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;isomerase activity#GO:0016853 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;epimerase/racemase#PC00096 MONDO|Ensembl=ENSMODG00000039759.1|UniProtKB=A0A5F8H2P5 A0A5F8H2P5 PTHR24390:SF290 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 184 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000017229.4|UniProtKB=F6WHU3 F6WHU3 DNAJC2 PTHR43999:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 2 DNAJ HOMOLOG SUBFAMILY C MEMBER 2 protein-folding chaperone binding#GO:0051087;heat shock protein binding#GO:0031072;Hsp70 protein binding#GO:0030544;binding#GO:0005488;protein binding#GO:0005515;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000025302.3|UniProtKB=F7F559 F7F559 MANSC4 PTHR46750:SF2 KUNITZ-TYPE PROTEASE INHIBITOR 1 MANSC DOMAIN-CONTAINING PROTEIN 4 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 cellular component organization#GO:0016043;cellular process#GO:0009987;tissue development#GO:0009888;epithelium development#GO:0060429;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;epidermis development#GO:0008544;developmental process#GO:0032502;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000005150.4|UniProtKB=F7EPR9 F7EPR9 NRXN3 PTHR15036:SF57 PIKACHURIN-LIKE PROTEIN NEUREXIN-3 transmembrane signaling receptor activity#GO:0004888;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;postsynaptic density assembly#GO:0097107;cellular component assembly#GO:0022607;nervous system development#GO:0007399;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;protein localization to synapse#GO:0035418;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;synapse assembly#GO:0007416;signaling#GO:0023052;excitatory synapse assembly#GO:1904861;animal gross anatomical part developmental process#GO:0160108;nervous system process#GO:0050877;postsynaptic density organization#GO:0097106;macromolecule localization#GO:0033036;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;developmental process#GO:0032502;intracellular protein localization#GO:0008104;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;postsynapse organization#GO:0099173;organelle assembly#GO:0070925;protein localization to cell junction#GO:1902414;cognition#GO:0050890;synapse organization#GO:0050808;cell communication#GO:0007154;localization#GO:0051179;anatomical structure development#GO:0048856;postsynaptic specialization organization#GO:0099084;system development#GO:0048731 synaptic membrane#GO:0097060;cell junction#GO:0030054;presynaptic active zone#GO:0048786;membrane#GO:0016020;presynaptic active zone membrane#GO:0048787;presynapse#GO:0098793;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000024615.2|UniProtKB=F6PPS8 F6PPS8 PTHR31996:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 115 VACUOLAR ATPASE ASSEMBLY PROTEIN VMA22 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;biological regulation#GO:0065007;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;vacuolar acidification#GO:0007035 cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;proton-transporting two-sector ATPase complex#GO:0016469;endoplasmic reticulum#GO:0005783;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;transporter complex#GO:1990351;vacuolar membrane#GO:0005774 MONDO|Ensembl=ENSMODG00000022821.2|UniProtKB=H9H9C8 H9H9C8 LOC100014996 PTHR11406:SF0 PHOSPHOGLYCERATE KINASE PHOSPHOGLYCERATE KINASE heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;purine ribonucleoside triphosphate binding#GO:0035639;kinase activity#GO:0016301;ribonucleotide binding#GO:0032553;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;transferase activity, transferring phosphorus-containing groups#GO:0016772;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphoglycerate kinase activity#GO:0004618 ATP metabolic process#GO:0046034;gluconeogenesis#GO:0006094;nicotinamide nucleotide metabolic process#GO:0046496;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;energy derivation by oxidation of organic compounds#GO:0015980;small molecule biosynthetic process#GO:0044283;nucleotide catabolic process#GO:0009166;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;nucleoside diphosphate catabolic process#GO:0009134;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine nucleotide catabolic process#GO:0006195;carbohydrate biosynthetic process#GO:0016051;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ADP catabolic process#GO:0046032;pyruvate metabolic process#GO:0006090;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;monocarboxylic acid metabolic process#GO:0032787;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate catabolic process#GO:1901292;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphoglycerate kinase#P00671 MONDO|Ensembl=ENSMODG00000025738.3|UniProtKB=F6T204 F6T204 CCDC175 PTHR35347:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 175 COILED-COIL DOMAIN-CONTAINING PROTEIN 175 MONDO|Ensembl=ENSMODG00000023682.3|UniProtKB=F6T194 F6T194 PTHR24376:SF245 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 585A gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017688.3|UniProtKB=F7G5N8 F7G5N8 B2M PTHR19944:SF62 MHC CLASS II-RELATED BETA-2-MICROGLOBULIN protein-containing complex binding#GO:0044877;binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277 regulation of lymphocyte activation#GO:0051249;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;immune system process#GO:0002376;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of T cell activation#GO:0050863;regulation of multicellular organismal process#GO:0051239;positive regulation of cell-cell adhesion#GO:0022409;cellular component biogenesis#GO:0044085;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;positive regulation of leukocyte activation#GO:0002696;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of cell adhesion#GO:0045785;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;positive regulation of cellular process#GO:0048522;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583 membrane#GO:0016020;vesicle membrane#GO:0012506;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;endomembrane system#GO:0012505;late endosome#GO:0005770;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;late endosome membrane#GO:0031902;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 MONDO|Ensembl=ENSMODG00000012687.4|UniProtKB=A0A5F8G4K2 A0A5F8G4K2 CACNB1 PTHR11824:SF17 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-1 voltage-gated ion channel#PC00241 Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041 MONDO|Ensembl=ENSMODG00000013206.4|UniProtKB=F7EWE9 F7EWE9 COL5A1 PTHR24023:SF1127 COLLAGEN ALPHA COLLAGEN TYPE V ALPHA 1 CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organismal process#GO:0032501;skin development#GO:0043588;skeletal system morphogenesis#GO:0048705;cellular process#GO:0009987;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;system development#GO:0048731;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;animal organ morphogenesis#GO:0009887;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 interstitial matrix#GO:0005614;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000008752.3|UniProtKB=F6PSD9 F6PSD9 PTHR11371:SF11 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE nuclease activity#GO:0004518;DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nucleic acid binding#GO:0003676;binding#GO:0005488;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;DNA catabolic process#GO:0006308;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 endodeoxyribonuclease#PC00093 MONDO|Ensembl=ENSMODG00000015827.4|UniProtKB=F7FDW3 F7FDW3 PTHR11749:SF3 RIBULOSE-5-PHOSPHATE-3-EPIMERASE RIBULOSE-PHOSPHATE 3-EPIMERASE ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;D-ribulose-phosphate 3-epimerase activity#GO:0004750;metal ion binding#GO:0046872;cation binding#GO:0043169;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;isomerase activity#GO:0016853 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052;pentose-phosphate shunt#GO:0006098;pyridine-containing compound metabolic process#GO:0072524;glyceraldehyde-3-phosphate metabolic process#GO:0019682;NADPH regeneration#GO:0006740;nucleotide metabolic process#GO:0009117;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Ascorbate degradation#P02729>L-xylulose-5-phosphate-3-epimerase#P02852 MONDO|Ensembl=ENSMODG00000000158.4|UniProtKB=A0A5F8GTG1 A0A5F8GTG1 CHP1 PTHR46002:SF1 EG:114D9.1 PROTEIN-RELATED CALCINEURIN B HOMOLOGOUS PROTEIN 1 calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of calcium-mediated signaling#GO:0050848;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of calcineurin-NFAT signaling cascade#GO:0070884;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000028432.2|UniProtKB=K7E690 K7E690 LOC103104413 PTHR11437:SF24 RIBONUCLEASE RIBONUCLEASE PANCREATIC catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;defense response#GO:0006952 RNA metabolism protein#PC00031;endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000006897.4|UniProtKB=F6PV30 F6PV30 MFSD12 PTHR11328:SF50 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 12 L-amino acid transmembrane transporter activity#GO:0015179;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;amino acid transmembrane transporter activity#GO:0015171 pigmentation#GO:0043473;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;localization#GO:0051179;regulation of biological process#GO:0050789;L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;regulation of cellular process#GO:0050794;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;nitrogen compound transport#GO:0071705;pigment metabolic process#GO:0042440;L-amino acid transport#GO:0015807;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000001448.4|UniProtKB=F7BBW4 F7BBW4 PRDM4 PTHR16515:SF2 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 4 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000012720.4|UniProtKB=F6TI60 F6TI60 CATSPER3 PTHR47131:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 3 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 3 voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843 anatomical structure development#GO:0048856;localization#GO:0051179;monoatomic cation transport#GO:0006812;multicellular organismal reproductive process#GO:0048609;spermatid development#GO:0007286;sexual reproduction#GO:0019953;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;metal ion transport#GO:0030001;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;cell maturation#GO:0048469;flagellated sperm motility#GO:0030317;transport#GO:0006810;spermatogenesis#GO:0007283;developmental process#GO:0032502;male gamete generation#GO:0048232;developmental maturation#GO:0021700;cilium-dependent cell motility#GO:0060285;monoatomic ion transport#GO:0006811;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;gamete generation#GO:0007276;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;sodium ion transport#GO:0006814;sperm motility#GO:0097722;microtubule-based process#GO:0007017;sperm capacitation#GO:0048240;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;vesicle#GO:0031982;voltage-gated calcium channel complex#GO:0005891;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;transporter complex#GO:1990351;cation channel complex#GO:0034703;cytoplasm#GO:0005737;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000009468.3|UniProtKB=F7FZ80 F7FZ80 PTHR12629:SF6 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule catabolic process#GO:0044282;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;alcohol metabolic process#GO:0006066;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000005090.4|UniProtKB=A0A5F8H4H9 A0A5F8H4H9 GDPD4 PTHR23344:SF13 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 6 hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000016844.3|UniProtKB=A0A5F8HG31 A0A5F8HG31 BIRC7 PTHR10044:SF163 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 7 enzyme regulator activity#GO:0030234;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell cycle#GO:0051726;positive regulation of protein metabolic process#GO:0051247;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;negative regulation of programmed cell death#GO:0043069;positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of protein ubiquitination#GO:0031396;regulation of apoptotic process#GO:0042981;regulation of protein modification process#GO:0031399 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000018045.4|UniProtKB=F6ZW32 F6ZW32 CD47 PTHR10613:SF0 LEUKOCYTE SURFACE ANTIGEN CD47 LEUKOCYTE SURFACE ANTIGEN CD47 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000023709.3|UniProtKB=F6QRG5 F6QRG5 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018939.4|UniProtKB=F7GB29 F7GB29 QRFPR PTHR24241:SF119 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PYROGLUTAMYLATED RF-AMIDE PEPTIDE RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000042946.1|UniProtKB=A0A5F8HBU4 A0A5F8HBU4 CCDC124 PTHR21680:SF0 COILED-COIL DOMAIN-CONTAINING PROTEIN 124 COILED-COIL DOMAIN-CONTAINING PROTEIN 124 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000016228.4|UniProtKB=F6TWV1 F6TWV1 SLC13A3 PTHR10283:SF62 SOLUTE CARRIER FAMILY 13 MEMBER NA(+)_DICARBOXYLATE COTRANSPORTER 3 dicarboxylic acid transmembrane transporter activity#GO:0005310;solute:monoatomic cation symporter activity#GO:0015294;succinate transmembrane transporter activity#GO:0015141;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;transmembrane transporter activity#GO:0022857;solute:sodium symporter activity#GO:0015370;C4-dicarboxylate transmembrane transporter activity#GO:0015556;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;citrate transmembrane transporter activity#GO:0015137;symporter activity#GO:0015293 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;tricarboxylic acid transport#GO:0006842;organic acid transport#GO:0015849;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;carboxylic acid transport#GO:0046942;citrate transport#GO:0015746;carboxylic acid transmembrane transport#GO:1905039;dicarboxylic acid transport#GO:0006835;succinate transport#GO:0015744;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000046555.1|UniProtKB=F7GKV8 F7GKV8 LOC100016943 PTHR48018:SF168 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025753.2|UniProtKB=F7G3P8 F7G3P8 PTHR23299:SF24 METALLOTHIONEIN METALLOTHIONEIN-1E-RELATED defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000044297.1|UniProtKB=A0A5F8H3B6 A0A5F8H3B6 NDUFS4 PTHR12219:SF29 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 4, MITOCHONDRIAL mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular respiration#GO:0045333;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;electron transport chain#GO:0022900;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;energy derivation by oxidation of organic compounds#GO:0015980;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;transporter complex#GO:1990351;respiratory chain complex I#GO:0045271;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000020619.4|UniProtKB=F6ZAT4 F6ZAT4 CORIN PTHR24270:SF2 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED ATRIAL NATRIURETIC PEPTIDE-CONVERTING ENZYME regulation of blood pressure#GO:0008217;circulatory system process#GO:0003013;biological regulation#GO:0065007;system process#GO:0003008;regulation of biological quality#GO:0065008;blood circulation#GO:0008015;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transfer/carrier protein#PC00219;apolipoprotein#PC00052 MONDO|Ensembl=ENSMODG00000000635.4|UniProtKB=F6TAD0 F6TAD0 RAC2 PTHR24072:SF169 RHO FAMILY GTPASE RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2 ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;protein binding#GO:0005515;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265 locomotion#GO:0040011;regulation of developmental process#GO:0050793;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of leukocyte migration#GO:0002685;regulation of cytoskeleton organization#GO:0051493;cellular response to stimulus#GO:0051716;regulation of cell projection assembly#GO:0060491;supramolecular fiber organization#GO:0097435;regulation of cell motility#GO:2000145;cell communication#GO:0007154;positive regulation of cell projection organization#GO:0031346;actin filament-based process#GO:0030029;chemotaxis#GO:0006935;cortical cytoskeleton organization#GO:0030865;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;response to external stimulus#GO:0009605;actin filament organization#GO:0007015;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell migration#GO:0030334;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;regulation of plasma membrane bounded cell projection assembly#GO:0120032;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;positive regulation of cellular component organization#GO:0051130;establishment or maintenance of cell polarity#GO:0007163;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;taxis#GO:0042330;response to chemical#GO:0042221;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;organelle organization#GO:0006996;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208;G-protein#PC00020 Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;p38 MAPK pathway#P05918>Rac#P06021;B cell activation#P00010>Rac#P00385;VEGF signaling pathway#P00056>Rac#P01421;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;Axon guidance mediated by semaphorins#P00007>Rac#P00340;Axon guidance mediated by netrin#P00009>Rac#P00366;FGF signaling pathway#P00021>Rac#P00645;Huntington disease#P00029>Rac#P00775;Integrin signalling pathway#P00034>Rac#P00927;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;T cell activation#P00053>rac#P01324;Ras Pathway#P04393>Rac#P04559;EGF receptor signaling pathway#P00018>Rac#P00564 MONDO|Ensembl=ENSMODG00000002613.4|UniProtKB=F6TCR1 F6TCR1 OGDHL PTHR23152:SF5 2-OXOGLUTARATE DEHYDROGENASE 2-OXOGLUTARATE DEHYDROGENASE-LIKE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 cytosol#GO:0005829;oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000003137.3|UniProtKB=A0A5F8GZ98 A0A5F8GZ98 PTHR46942:SF1 SIALIC ACID-BINDING IG-LIKE LECTIN 15 SIALIC ACID-BINDING IG-LIKE LECTIN 15 regulation of actin filament-based process#GO:0032970;regulation of cell differentiation#GO:0045595;regulation of bone remodeling#GO:0046850;regulation of cell development#GO:0060284;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of actin cytoskeleton organization#GO:0032956;regulation of bone resorption#GO:0045124;regulation of hemopoiesis#GO:1903706;regulation of tissue remodeling#GO:0034103;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of organelle organization#GO:0033043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000041110.1|UniProtKB=A0A5F8H0J5 A0A5F8H0J5 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002363.4|UniProtKB=F7GDK9 F7GDK9 ASB1 PTHR24173:SF27 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT AND SOCS BOX PROTEIN 1 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006171.4|UniProtKB=A0A5F8HER3 A0A5F8HER3 PTHR19229:SF274 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ABC-TYPE ORGANIC ANION TRANSPORTER ABCA8 molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 lipid localization#GO:0010876;macromolecule localization#GO:0033036;transport#GO:0006810;lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000017401.4|UniProtKB=F6SKA1 F6SKA1 NAMPT PTHR43816:SF1 NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000037819.1|UniProtKB=F7D5P0 F7D5P0 LOC100026015 PTHR26453:SF570 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023545.2|UniProtKB=F7AI91 F7AI91 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000013944.3|UniProtKB=F6SBS0 F6SBS0 CFAP184 PTHR15654:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 113-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 184 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000007004.2|UniProtKB=F6XUJ0 F6XUJ0 KCNJ11 PTHR11767:SF44 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 11 channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215 import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000006202.4|UniProtKB=F6ZTK0 F6ZTK0 AREL1 PTHR11254:SF340 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE APOPTOSIS-RESISTANT E3 UBIQUITIN PROTEIN LIGASE 1 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;catabolic process#GO:0009056;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000014961.4|UniProtKB=A0A5F8GUG0 A0A5F8GUG0 NGLY1 PTHR12143:SF45 PEPTIDE N-GLYCANASE PNGASE -RELATED PEPTIDE-N(4)-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 regulation of BMP signaling pathway#GO:0030510;positive regulation of cellular process#GO:0048522;carbohydrate derivative metabolic process#GO:1901135;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;glycoprotein metabolic process#GO:0009100;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;positive regulation of BMP signaling pathway#GO:0030513;positive regulation of signal transduction#GO:0009967;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;carbohydrate derivative catabolic process#GO:1901136;regulation of cell communication#GO:0010646;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;protein metabolic process#GO:0019538;positive regulation of signaling#GO:0023056 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 MONDO|Ensembl=ENSMODG00000019542.4|UniProtKB=F6UUE8 F6UUE8 WDR93 PTHR12219:SF17 NADH-UBIQUINONE OXIDOREDUCTASE WD REPEAT-CONTAINING PROTEIN 93 cellular component organization or biogenesis#GO:0071840;energy derivation by oxidation of organic compounds#GO:0015980;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;cellular respiration#GO:0045333;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000023732.1|UniProtKB=F6QP90 F6QP90 SMIM3 PTHR37859:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 3 SMALL INTEGRAL MEMBRANE PROTEIN 3 MONDO|Ensembl=ENSMODG00000020105.4|UniProtKB=F7ERY8 F7ERY8 YPEL4 PTHR13848:SF17 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 4 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000028863.2|UniProtKB=K7DZI3 K7DZI3 PTHR46386:SF1 NUCLEAR BODY PROTEIN SP140 RIKEN CDNA A630001G21 GENE DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000015037.4|UniProtKB=F7BX89 F7BX89 PPIL3 PTHR45625:SF2 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3 peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000051065.1|UniProtKB=F6TMT7 F6TMT7 LOC100619642 PTHR26453:SF44 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1330-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001556.4|UniProtKB=F7E616 F7E616 TSPAN14 PTHR19282:SF261 TETRASPANIN TETRASPANIN-14 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000039373.1|UniProtKB=A0A5F8G7A7 A0A5F8G7A7 C11orf98 PTHR14554:SF1 GENE, 49416-RELATED 28S RRNA_RIBOSOME AND SORORIN MICRO-COFACTOR MONDO|Ensembl=ENSMODG00000024619.2|UniProtKB=F6PPA9 F6PPA9 PTHR21223:SF4 CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN 1 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;ciliary transition zone#GO:0035869;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000027316.2|UniProtKB=K7E240 K7E240 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000025078.2|UniProtKB=F6R5T8 F6R5T8 PTHR11280:SF8 GLUCOSAMINE-6-PHOSPHATE ISOMERASE GLUCOSAMINE-6-PHOSPHATE DEAMINASE 1 binding#GO:0005488;catalytic activity#GO:0003824;identical protein binding#GO:0042802;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;protein binding#GO:0005515;hydrolase activity#GO:0016787 carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino sugar catabolic process#GO:0046348 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 isomerase#PC00135 N-acetylglucosamine metabolism#P02756>Glucosamine-6-phosphate deaminase#P03041 MONDO|Ensembl=ENSMODG00000020331.2|UniProtKB=F7G7A6 F7G7A6 MS4A15 PTHR23320:SF51 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 15 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000017133.3|UniProtKB=F6U382 F6U382 CKS1B PTHR23415:SF29 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT-RELATED protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000008994.4|UniProtKB=F7BQA0 F7BQA0 ARMC3 PTHR46618:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 3 ARMADILLO REPEAT-CONTAINING PROTEIN 3 MONDO|Ensembl=ENSMODG00000013883.3|UniProtKB=F6W8F1 F6W8F1 KRTDAP PTHR36463:SF1 KERATINOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN KERATINOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN epidermis development#GO:0008544;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;tissue development#GO:0009888;anatomical structure development#GO:0048856 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000000704.4|UniProtKB=F6WLI3 F6WLI3 TMEM163 PTHR31937:SF2 TRANSMEMBRANE PROTEIN 163 TRANSMEMBRANE PROTEIN 163 cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;zinc ion binding#GO:0008270;small molecule binding#GO:0036094;binding#GO:0005488 exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133 MONDO|Ensembl=ENSMODG00000011659.4|UniProtKB=F7D2K9 F7D2K9 GLI4 PTHR23226:SF197 ZINC FINGER AND SCAN DOMAIN-CONTAINING GLI FAMILY ZINC FINGER 4 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004719.4|UniProtKB=F7DQF9 F7DQF9 PTHR24376:SF210 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 721-RELATED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000012828.4|UniProtKB=F7DD44 F7DD44 RPL11 PTHR11994:SF8 60S RIBOSOMAL PROTEIN L11-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL5 nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000045333.1|UniProtKB=A0A5F8H7N7 A0A5F8H7N7 PTHR26452:SF204 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000008751.4|UniProtKB=F6PRU1 F6PRU1 INPP5F PTHR45662:SF8 PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 PHOSPHATIDYLINOSITIDE 4-PHOSPHATASE SAC2 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;metabolic process#GO:0008152;regulation of localization#GO:0032879;regulation of transport#GO:0051049;lipid modification#GO:0030258;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol dephosphorylation#GO:0046856;dephosphorylation#GO:0016311;phosphate-containing compound metabolic process#GO:0006796;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;glycerolipid metabolic process#GO:0046486 endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle#GO:0030136;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737 phosphatase#PC00181;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000023268.2|UniProtKB=F6WQT0 F6WQT0 C6orf120 PTHR31703:SF2 UPF0669 PROTEIN C6ORF120 UPF0669 PROTEIN C6ORF120 MONDO|Ensembl=ENSMODG00000018857.4|UniProtKB=F7CMW7 F7CMW7 ZNF687 PTHR47222:SF2 ZINC FINGER PROTEIN 532-RELATED ZINC FINGER PROTEIN 687 MONDO|Ensembl=ENSMODG00000008093.4|UniProtKB=F7GFV9 F7GFV9 RNF145 PTHR22763:SF167 RING ZINC FINGER PROTEIN RING FINGER PROTEIN 145 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000005563.2|UniProtKB=F7F3P0 F7F3P0 VMO1 PTHR18841:SF2 VITELLINE MEMBRANE OUTER LAYER PROTEIN I-RELATED VITELLINE MEMBRANE OUTER LAYER PROTEIN 1 HOMOLOG extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000025638.3|UniProtKB=F6XW63 F6XW63 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014816.4|UniProtKB=A0A5F8G9L0 A0A5F8G9L0 PTHR11801:SF39 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 5B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;response to peptide hormone#GO:0043434;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to nitrogen compound#GO:1901699;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;cellular response to peptide hormone stimulus#GO:0071375;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway via STAT#GO:0097696;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;response to stress#GO:0006950;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to hormone stimulus#GO:0032870;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;response to peptide#GO:1901652;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561;PDGF signaling pathway#P00047>STAT#P01173;JAK/STAT signaling pathway#P00038>STAT#P01027 MONDO|Ensembl=ENSMODG00000016685.4|UniProtKB=F6S038 F6S038 BNIP3L PTHR15186:SF3 RE48077P BCL2_ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 3-LIKE regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;cellular component organization#GO:0016043;catabolic process#GO:0009056;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;process utilizing autophagic mechanism#GO:0061919;autophagy#GO:0006914;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;apoptotic mitochondrial changes#GO:0008637;macroautophagy#GO:0016236;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;mitophagy#GO:0000423 endoplasmic reticulum#GO:0005783;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;nucleus#GO:0005634;organelle outer membrane#GO:0031968;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000040429.1|UniProtKB=K7E544 K7E544 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003861.5|UniProtKB=F7DTY9 F7DTY9 PTHR45080:SF31 CONTACTIN 5 ROUNDABOUT HOMOLOG 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell junction organization#GO:0034330;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cell adhesion#GO:0007155 plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell body#GO:0044297;neuron projection#GO:0043005;membrane#GO:0016020;axon#GO:0030424 Axon guidance mediated by Slit/Robo#P00008>Robo#P00348 MONDO|Ensembl=ENSMODG00000014140.3|UniProtKB=F6XKM3 F6XKM3 PRSS54 PTHR24250:SF45 CHYMOTRYPSIN-RELATED INACTIVE SERINE PROTEASE 54 catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein modifying enzyme#PC00260;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000017335.4|UniProtKB=F6WVQ2 F6WVQ2 MAMDC4 PTHR23282:SF129 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. APICAL ENDOSOMAL GLYCOPROTEIN MONDO|Ensembl=ENSMODG00000008904.4|UniProtKB=F7GLA2 F7GLA2 NF2 PTHR23281:SF23 MERLIN/MOESIN/EZRIN/RADIXIN MERLIN integrin binding#GO:0005178;cytoskeletal protein binding#GO:0008092;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;binding#GO:0005488;actin binding#GO:0003779 regulation of hippo signaling#GO:0035330;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of multicellular organismal process#GO:0051239;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of neurogenesis#GO:0050767;regulation of nervous system development#GO:0051960;regulation of cell population proliferation#GO:0042127;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell development#GO:0060284;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;negative regulation of cell population proliferation#GO:0008285;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523 actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;filopodium#GO:0030175;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;adherens junction#GO:0005912;cell junction#GO:0030054;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000010108.3|UniProtKB=F6X4J5 F6X4J5 TM7SF2 PTHR21257:SF59 DELTA(14)-STEROL REDUCTASE DELTA(14)-STEROL REDUCTASE TM7SF2 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;secondary alcohol biosynthetic process#GO:1902653;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle envelope#GO:0031967;nuclear membrane#GO:0031965;nuclear inner membrane#GO:0005637;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endomembrane system#GO:0012505;organelle inner membrane#GO:0019866;nucleus#GO:0005634;membrane#GO:0016020 reductase#PC00198;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000012343.4|UniProtKB=F7E232 F7E232 LOC100010148 PTHR11783:SF48 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1 FAMILY MEMBER D1 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000041424.1|UniProtKB=A0A5F8GSZ8 A0A5F8GSZ8 PTHR23260:SF10 KERATIN ASSOCIATED PROTEIN 3-3-RELATED GENE 11939-RELATED structural protein#PC00211 MONDO|Ensembl=ENSMODG00000015002.5|UniProtKB=F7CG63 F7CG63 STXBP2 PTHR11679:SF27 VESICLE PROTEIN SORTING-ASSOCIATED SYNTAXIN-BINDING PROTEIN 2 protein binding#GO:0005515;syntaxin binding#GO:0019905;binding#GO:0005488;SNARE binding#GO:0000149 anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;organelle localization#GO:0051640;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;macromolecule localization#GO:0033036;vesicle localization#GO:0051648;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;calcium-ion regulated exocytosis#GO:0017156;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of organelle localization#GO:0051656;signaling#GO:0023052;export from cell#GO:0140352;regulation of biological process#GO:0050789;cellular localization#GO:0051641;secretion by cell#GO:0032940;protein transport#GO:0015031;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;establishment of vesicle localization#GO:0051650;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;regulated exocytosis#GO:0045055;intracellular protein transport#GO:0006886 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000001350.4|UniProtKB=A0A5F8HJ80 A0A5F8HJ80 PTCD1 PTHR24014:SF6 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1, MITOCHONDRIAL tRNA binding#GO:0000049;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 mitochondrial RNA modification#GO:1900864;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA 3'-end processing#GO:0042780 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;mitochondrion#GO:0005739;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000016825.4|UniProtKB=F6R2R0 F6R2R0 PPIL4 PTHR45843:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000005108.5|UniProtKB=F6ZDR1 F6ZDR1 ADAMTS8 PTHR13723:SF41 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 8 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000018282.3|UniProtKB=F6Q6E1 F6Q6E1 PTHR23147:SF3 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 12 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear body#GO:0016604;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000039289.1|UniProtKB=A0A5F8GDX1 A0A5F8GDX1 LOC100011560 PTHR23430:SF220 HISTONE H2A HISTONE H2A TYPE 3 structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000003292.2|UniProtKB=A0A5F8HET4 A0A5F8HET4 GAS8 PTHR31543:SF3 DYNEIN REGULATORY COMPLEX SUBUNIT 4 DYNEIN REGULATORY COMPLEX SUBUNIT 4 microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cell motility#GO:0048870;microtubule-based movement#GO:0007018;regulation of cell communication#GO:0010646;reproductive process#GO:0022414;positive regulation of signal transduction#GO:0009967;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular process#GO:0048522;cilium-dependent cell motility#GO:0060285;positive regulation of signaling#GO:0023056;cilium organization#GO:0044782;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;regulation of signaling#GO:0023051;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;sperm motility#GO:0097722;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 Golgi apparatus#GO:0005794;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;sperm flagellum#GO:0036126;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000051343.1|UniProtKB=A0A5F8HAP5 A0A5F8HAP5 PTHR12700:SF12 ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL ATP SYNTHASE PERIPHERAL STALK SUBUNIT D, MITOCHONDRIAL channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;proton channel activity#GO:0015252;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803 purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate biosynthetic process#GO:1901293 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;proton-transporting ATP synthase complex#GO:0045259;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000012037.3|UniProtKB=F7ALM7 F7ALM7 CHSY1 PTHR12369:SF42 CHONDROITIN SYNTHASE CHONDROITIN SULFATE SYNTHASE 1 glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194 protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;glycoprotein biosynthetic process#GO:0009101;chondroitin sulfate proteoglycan metabolic process#GO:0050654;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000041193.1|UniProtKB=A0A5F8GX15 A0A5F8GX15 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000028655.2|UniProtKB=K7E2V9 K7E2V9 FCHO1 PTHR23065:SF6 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 F-BAR DOMAIN ONLY PROTEIN 1 establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular component assembly#GO:0022607;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000003437.3|UniProtKB=H9H632 H9H632 PTHR12059:SF5 RIBOSOMAL PROTEIN L23-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL23M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000000189.5|UniProtKB=A0A5F8GUX8 A0A5F8GUX8 BORA PTHR14728:SF2 PROTEIN AURORA BOREALIS PROTEIN AURORA BOREALIS protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of spindle organization#GO:0090224;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of nuclear division#GO:0051783;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of organelle organization#GO:0033043;regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789;regulation of mitotic spindle organization#GO:0060236;regulation of mitotic nuclear division#GO:0007088;regulation of microtubule-based process#GO:0032886 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000004764.3|UniProtKB=F6X0G0 F6X0G0 ANKEF1 PTHR24127:SF1 ANKYRIN REPEAT AND EF-HAND DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND EF-HAND DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000017224.4|UniProtKB=F6WXQ5 F6WXQ5 PMPCB PTHR11851:SF103 METALLOPROTEASE MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT BETA catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;macromolecule localization#GO:0033036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;endopeptidase complex#GO:1905369 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000025313.2|UniProtKB=F7ENK9 F7ENK9 GPR34 PTHR24233:SF1 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 34-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000012561.4|UniProtKB=F6PLL4 F6PLL4 AK8 PTHR23359:SF271 NUCLEOTIDE KINASE ADENYLATE KINASE 8 phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824 ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleoside diphosphate metabolic process#GO:0009132;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;nucleoside phosphate biosynthetic process#GO:1901293;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 nucleotide kinase#PC00172;kinase#PC00137 Salvage pyrimidine ribonucleotides#P02775>Cytidylate kinase#P03153;De novo purine biosynthesis#P02738>Adenylate kinase#P02896 MONDO|Ensembl=ENSMODG00000021442.4|UniProtKB=F7BT84 F7BT84 VAPA PTHR10809:SF155 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN A protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 developmental process#GO:0032502;neuron differentiation#GO:0030182;endoplasmic reticulum membrane organization#GO:0090158;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030 endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000027652.2|UniProtKB=K7DZ11 K7DZ11 PTHR10424:SF82 VIRAL ENVELOPE PROTEIN ENVELOPE POLYPROTEIN cellular process#GO:0009987;muscle cell differentiation#GO:0042692;myoblast fusion#GO:0007520;muscle structure development#GO:0061061;cell differentiation#GO:0030154;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;cell-cell fusion#GO:0140253;striated muscle cell differentiation#GO:0051146;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;syncytium formation by cell-cell fusion#GO:0000768 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000042320.1|UniProtKB=A0A5F8HE33 A0A5F8HE33 LOC100022293 PTHR26450:SF76 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51B5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000051586.1|UniProtKB=A0A5F8HLE7 A0A5F8HLE7 GUCD1 PTHR31400:SF1 GUANYLYL CYCLASE DOMAIN CONTAINING PROTEIN 1 GUCD1 PROTEIN GUCD1 guanylate cyclase#PC00114 MONDO|Ensembl=ENSMODG00000014658.3|UniProtKB=F7EPK1 F7EPK1 WDR59 PTHR46170:SF1 GATOR COMPLEX PROTEIN WDR59 GATOR2 COMPLEX PROTEIN WDR59 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of TORC1 signaling#GO:1903432;response to nutrient levels#GO:0031667;response to stress#GO:0006950;positive regulation of TORC1 signaling#GO:1904263;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;cellular response to amino acid starvation#GO:0034198;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774;Seh1-associated complex#GO:0035859;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000009829.4|UniProtKB=A0A5F8HF55 A0A5F8HF55 FBXO3 PTHR46550:SF7 F-BOX ONLY PROTEIN 3 F-BOX ONLY PROTEIN 3 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000003622.4|UniProtKB=A0A5F8G4W2 A0A5F8G4W2 UBA3 PTHR10953:SF6 UBIQUITIN-ACTIVATING ENZYME E1 NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;ligase activity#GO:0016874;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 MONDO|Ensembl=ENSMODG00000019686.4|UniProtKB=F6TTC0 F6TTC0 LHX6 PTHR24208:SF121 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX6 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 central nervous system neuron differentiation#GO:0021953;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;head development#GO:0060322;nervous system development#GO:0007399;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;regulation of biological process#GO:0050789;cell development#GO:0048468;forebrain development#GO:0030900;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;central nervous system development#GO:0007417 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000014569.5|UniProtKB=A0A5F8G2J9 A0A5F8G2J9 KLF4 PTHR23235:SF117 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 4 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 C2H2 zinc finger transcription factor#PC00248 CCKR signaling map#P06959>KLF4#P07227 MONDO|Ensembl=ENSMODG00000048305.1|UniProtKB=A0A5F8G5S9 A0A5F8G5S9 PTHR22691:SF8 YEAST SPT2-RELATED PROTEIN SPT2 HOMOLOG DNA binding#GO:0003677;protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;nucleic acid binding#GO:0003676 protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;transcription by RNA polymerase I#GO:0006360;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000001702.4|UniProtKB=F6S6T7 F6S6T7 ZNF366 PTHR24390:SF282 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 366 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of signal transduction#GO:0009968;response to chemical#GO:0042221;response to hormone#GO:0009725;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of DNA-templated transcription#GO:0045892;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019742.3|UniProtKB=F6WNU0 F6WNU0 PSMB7 PTHR11599:SF42 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-7 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 nucleus#GO:0005634;proteasome complex#GO:0000502;cytosol#GO:0005829;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 MONDO|Ensembl=ENSMODG00000000470.3|UniProtKB=F6URI1 F6URI1 CZIB PTHR12857:SF0 CXXC MOTIF CONTAINING ZINC BINDING PROTEIN CXXC MOTIF CONTAINING ZINC BINDING PROTEIN metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914 MONDO|Ensembl=ENSMODG00000023693.2|UniProtKB=F6PFZ3 F6PFZ3 PTHR23147:SF288 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 7 supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000008407.5|UniProtKB=A0A5F8H6B7 A0A5F8H6B7 PLXNB3 PTHR22625:SF33 PLEXIN PLEXIN-B3 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of anatomical structure morphogenesis#GO:0022603;regulation of axonogenesis#GO:0050770;negative regulation of cell migration#GO:0030336;positive regulation of cell differentiation#GO:0045597;cell surface receptor signaling pathway#GO:0007166;cellular component assembly#GO:0022607;negative regulation of locomotion#GO:0040013;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;positive regulation of axonogenesis#GO:0050772;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;positive regulation of cellular component organization#GO:0051130;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;response to stimulus#GO:0050896;synapse assembly#GO:0007416;signaling#GO:0023052;cell junction assembly#GO:0034329;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of cell shape#GO:0008360;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of cell differentiation#GO:0045595;negative regulation of cell adhesion#GO:0007162;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;system development#GO:0048731;synapse organization#GO:0050808;positive regulation of cell projection organization#GO:0031346;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023287.2|UniProtKB=F6WPH3 F6WPH3 LOC103104853 PTHR10026:SF70 CYCLIN CYCLIN-Q enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 kinase activator#PC00138;kinase modulator#PC00140 MONDO|Ensembl=ENSMODG00000051556.1|UniProtKB=K7E5S7 K7E5S7 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000048994.1|UniProtKB=A0A5F8GM00 A0A5F8GM00 PTHR48067:SF1 GPI-ANCHOR TRANSAMIDASE GPI-ANCHOR TRANSAMIDASE cysteine-type peptidase activity#GO:0008234;transferase activity#GO:0016740;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;GPI anchored protein biosynthesis#GO:0180046;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 membrane#GO:0016020;caspase complex#GO:0008303;cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000007676.3|UniProtKB=F7FNG6 F7FNG6 GTF2H5 PTHR28580:SF1 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5 protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-excision repair#GO:0006289;protein-DNA complex assembly#GO:0065004;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transcription factor TFIIH holo complex#GO:0005675;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;transcription factor TFIIH core complex#GO:0000439;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000001452.3|UniProtKB=H9H5X6 H9H5X6 PTHR21051:SF4 CAMP-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE 2 CAMP-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE 2 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000017283.4|UniProtKB=F6SMV1 F6SMV1 HNRNPH3 PTHR13976:SF36 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H3 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000018952.4|UniProtKB=F7DYS6 F7DYS6 MRPS18A PTHR13479:SF66 30S RIBOSOMAL PROTEIN S18 LARGE RIBOSOMAL SUBUNIT PROTEIN ML66 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;mitochondrial small ribosomal subunit#GO:0005763;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000012122.3|UniProtKB=A0A5F8H5E5 A0A5F8H5E5 CHST8 PTHR12137:SF7 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 8 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029 transferase#PC00220 MONDO|Ensembl=ENSMODG00000011837.4|UniProtKB=F7GLN8 F7GLN8 SRPX2 PTHR46343:SF3 HYR DOMAIN-CONTAINING PROTEIN SUSHI REPEAT-CONTAINING PROTEIN SRPX2 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of locomotion#GO:0040012;regulation of synapse assembly#GO:0051963;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;positive regulation of locomotion#GO:0040017;positive regulation of synapse assembly#GO:0051965;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;positive regulation of cell motility#GO:2000147;regulation of biological quality#GO:0065008;regulation of cell motility#GO:2000145;regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;cell adhesion#GO:0007155;positive regulation of cellular component organization#GO:0051130;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807 MONDO|Ensembl=ENSMODG00000005002.4|UniProtKB=F7BNC0 F7BNC0 SLC38A8 PTHR22950:SF226 AMINO ACID TRANSPORTER SOLUTE CARRIER FAMILY 38 MEMBER 8 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;amino acid transporter#PC00046 MONDO|Ensembl=ENSMODG00000015940.4|UniProtKB=F6Z357 F6Z357 CHRNA2 PTHR18945:SF757 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-2 ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;acetylcholine receptor activity#GO:0015464;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;monoatomic cation transmembrane transporter activity#GO:0008324 acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;transport#GO:0006810;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;metal ion transport#GO:0030001;modulation of chemical synaptic transmission#GO:0050804;membrane depolarization#GO:0051899;trans-synaptic signaling#GO:0099537;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;synaptic signaling#GO:0099536;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;neuromuscular synaptic transmission#GO:0007274;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008 plasma membrane protein complex#GO:0098797;postsynapse#GO:0098794;membrane protein complex#GO:0098796;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;transporter complex#GO:1990351;cell junction#GO:0030054 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 MONDO|Ensembl=ENSMODG00000009097.3|UniProtKB=A0A5F8GEP6 A0A5F8GEP6 MAP4K3 PTHR48012:SF17 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861;Apoptosis signaling pathway#P00006>GCKR#P00311 MONDO|Ensembl=ENSMODG00000002819.4|UniProtKB=A0A5F8GT23 A0A5F8GT23 RALY PTHR13968:SF6 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN RALY RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000001507.4|UniProtKB=F7F4F7 F7F4F7 EDNRB PTHR46099:SF3 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ENDOTHELIN RECEPTOR TYPE B transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;regulation of biological quality#GO:0065008;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;pigmentation#GO:0043473;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;system process#GO:0003008;regulation of anatomical structure size#GO:0090066;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;biological regulation#GO:0065007;cellular process#GO:0009987;developmental pigmentation#GO:0048066;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 Endothelin signaling pathway#P00019>ET-RA/B#P00580 MONDO|Ensembl=ENSMODG00000003547.2|UniProtKB=F7GBL2 F7GBL2 PTHR48018:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8B8 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000047250.1|UniProtKB=A0A5F8H7B4 A0A5F8H7B4 PTHR46479:SF1 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 protein binding#GO:0005515;binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular transport#GO:0046907;organelle localization#GO:0051640;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lysosome localization#GO:0032418 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;BLOC-1 complex#GO:0031083;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000007937.4|UniProtKB=A0A5F8HDW0 A0A5F8HDW0 CLPB PTHR11638:SF93 ATP-DEPENDENT CLP PROTEASE MITOCHONDRIAL DISAGGREGASE hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787 cellular response to heat#GO:0034605;response to heat#GO:0009408;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to temperature stimulus#GO:0009266;cellular response to stress#GO:0033554 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000017287.4|UniProtKB=F6SM32 F6SM32 HECA PTHR13425:SF3 HEADCASE PROTEIN HEADCASE PROTEIN HOMOLOG MONDO|Ensembl=ENSMODG00000011031.4|UniProtKB=F7F4B9 F7F4B9 NSF PTHR23078:SF3 VESICULAR-FUSION PROTEIN NSF VESICLE-FUSING ATPASE ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to cell periphery#GO:1990778;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>NSF#P05774;Ionotropic glutamate receptor pathway#P00037>NSF#P01020 MONDO|Ensembl=ENSMODG00000011128.3|UniProtKB=F7BB66 F7BB66 E2F6 PTHR12081:SF19 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000004617.3|UniProtKB=F6Y3D8 F6Y3D8 DCPS PTHR12978:SF0 HISTIDINE TRIAD HIT PROTEIN MEMBER M7GPPPX DIPHOSPHATASE RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;RNA catabolic process#GO:0006401;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;RNA decapping#GO:0110154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;P-body#GO:0000932;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000047495.1|UniProtKB=A0A5F8GBL9 A0A5F8GBL9 CAV2 PTHR10844:SF3 CAVEOLIN CAVEOLIN-2 kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515 endomembrane system organization#GO:0010256;response to chemical#GO:0042221;cellular component assembly#GO:0022607;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;response to hormone#GO:0009725;monoatomic ion homeostasis#GO:0050801;intracellular calcium ion homeostasis#GO:0006874;cellular component organization or biogenesis#GO:0071840;chemical homeostasis#GO:0048878;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;membrane assembly#GO:0071709;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;intracellular monoatomic ion homeostasis#GO:0006873;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;plasma membrane organization#GO:0007009;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;inorganic ion homeostasis#GO:0098771;cellular response to chemical stimulus#GO:0070887;calcium ion homeostasis#GO:0055074;biological regulation#GO:0065007;membrane organization#GO:0061024;response to peptide hormone#GO:0043434;cellular response to nitrogen compound#GO:1901699;negative regulation of cell population proliferation#GO:0008285;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;cellular developmental process#GO:0048869;developmental process#GO:0032502;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;cellular response to insulin stimulus#GO:0032869;negative regulation of cellular process#GO:0048523;homeostatic process#GO:0042592;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of cytosolic calcium ion concentration#GO:0051480;response to insulin#GO:0032868;response to nitrogen compound#GO:1901698;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 intracellular organelle#GO:0043229;plasma membrane raft#GO:0044853;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;anchoring junction#GO:0070161;intracellular vesicle#GO:0097708;membrane raft#GO:0045121;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane microdomain#GO:0098857;sarcolemma#GO:0042383;cell junction#GO:0030054;caveola#GO:0005901;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000023750.2|UniProtKB=F6TEL7 F6TEL7 LOC100028143 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005906.3|UniProtKB=F6XD22 F6XD22 LOC100616903 PTHR26452:SF806 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A16 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000029116.2|UniProtKB=K7E4Q3 K7E4Q3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000005821.4|UniProtKB=F7F9A2 F7F9A2 PTHR22950:SF708 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED L-amino acid transmembrane transporter activity#GO:0015179;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;amino acid transporter#PC00046 MONDO|Ensembl=ENSMODG00000002477.4|UniProtKB=A0A5F8GHN0 A0A5F8GHN0 TRAF3IP1 PTHR31363:SF0 TRAF3-INTERACTING PROTEIN 1 TRAF3-INTERACTING PROTEIN 1 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;microtubule-based transport#GO:0099111;cilium organization#GO:0044782;cellular localization#GO:0051641;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of microtubule cytoskeleton organization#GO:0070507;cellular component assembly#GO:0022607;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;localization#GO:0051179;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport along microtubule#GO:0010970;establishment of localization#GO:0051234 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;intraciliary transport particle B#GO:0030992 MONDO|Ensembl=ENSMODG00000050846.1|UniProtKB=F6TKN0 F6TKN0 TESC PTHR46823:SF2 CALCINEURIN B HOMOLOGOUS PROTEIN 3 CALCINEURIN B HOMOLOGOUS PROTEIN 3 calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;molecular function inhibitor activity#GO:0140678;cation binding#GO:0043169;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208 regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell adhesion mediated by integrin#GO:0033628;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;cellular localization#GO:0051641;localization#GO:0051179;regulation of hemopoiesis#GO:1903706;localization within membrane#GO:0051668;regulation of myeloid cell differentiation#GO:0045637;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;cellular process#GO:0009987;regulation of cell development#GO:0060284;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of myeloid cell differentiation#GO:0045639;positive regulation of immune system process#GO:0002684;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;protein localization to cell periphery#GO:1990778 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000020452.4|UniProtKB=F7A342 F7A342 WDR7 PTHR44099:SF3 RABCONNECTIN-3B, ISOFORM A WD REPEAT-CONTAINING PROTEIN 7 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000012819.4|UniProtKB=F7DY26 F7DY26 NR2F2 PTHR24083:SF45 NUCLEAR HORMONE RECEPTOR COUP TRANSCRIPTION FACTOR 2 transcription regulatory region nucleic acid binding#GO:0001067;lipid binding#GO:0008289;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;carboxylic acid binding#GO:0031406;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;ion binding#GO:0043167;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;anion binding#GO:0043168;transcription cis-regulatory region binding#GO:0000976;organic acid binding#GO:0043177;sequence-specific double-stranded DNA binding#GO:1990837 nervous system development#GO:0007399;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;animal gross anatomical part developmental process#GO:0160108;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000024986.2|UniProtKB=F6XNN8 F6XNN8 PTHR12917:SF13 ASPARTYL PROTEASE DDI-RELATED PROTEIN DDI1 HOMOLOG 2 catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;catabolic process#GO:0009056;cellular process#GO:0009987;regulation of protein stability#GO:0031647;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;aspartic protease#PC00053 MONDO|Ensembl=ENSMODG00000021410.4|UniProtKB=F7CBX9 F7CBX9 CDH7 PTHR24027:SF91 CADHERIN-23 CADHERIN-7 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component assembly#GO:0022607;cell migration#GO:0016477;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;cell motility#GO:0048870;cell junction organization#GO:0034330;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cellular component organization#GO:0016043 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000011752.4|UniProtKB=F7DFA3 F7DFA3 TMEM35A PTHR13163:SF0 SPINAL CORD EXPRESSION PROTEIN 4 NOVEL ACETYLCHOLINE RECEPTOR CHAPERONE neurotransmitter receptor regulator activity#GO:0099602;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;acetylcholine receptor regulator activity#GO:0030548 regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;biological regulation#GO:0065007;cellular component assembly#GO:0022607;chaperone-mediated protein complex assembly#GO:0051131;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000038794.1|UniProtKB=A0A5F8G382 A0A5F8G382 PTHR23266:SF407 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN antigen binding#GO:0003823;binding#GO:0005488 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000010558.3|UniProtKB=F6YR92 F6YR92 MON1B PTHR13027:SF13 SAND PROTEIN-RELATED VACUOLAR FUSION PROTEIN MON1 HOMOLOG B molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endomembrane system#GO:0012505;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535 MONDO|Ensembl=ENSMODG00000038683.1|UniProtKB=A0A5F8HDK0 A0A5F8HDK0 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006068.5|UniProtKB=A0A5F8GI48 A0A5F8GI48 SALL2 PTHR23233:SF15 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000008026.4|UniProtKB=F7CKQ6 F7CKQ6 DNAI1 PTHR12442:SF11 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cilium movement#GO:0003341;organelle assembly#GO:0070925;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 outer dynein arm#GO:0036157;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular organelle#GO:0043229;cilium#GO:0005929;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;dynein complex#GO:0030286;axonemal dynein complex#GO:0005858;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000027343.2|UniProtKB=K7E2A7 K7E2A7 PLEKHM3 PTHR12326:SF10 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 3 MONDO|Ensembl=ENSMODG00000024281.2|UniProtKB=F6Z4Z1 F6Z4Z1 PTHR47400:SF1 PROLINE-RICH TRANSMEMBRANE PROTEIN 3 PROLINE-RICH TRANSMEMBRANE PROTEIN 3 MONDO|Ensembl=ENSMODG00000005505.4|UniProtKB=F7GFQ8 F7GFQ8 SEC13 PTHR11024:SF21 NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER PROTEIN SEC13 HOMOLOG localization#GO:0051179;nuclear transport#GO:0051169;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;positive regulation of TOR signaling#GO:0032008;nucleocytoplasmic transport#GO:0006913;COPII-coated vesicle budding#GO:0090114;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle budding from membrane#GO:0006900;intracellular transport#GO:0046907;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;membrane organization#GO:0061024;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;positive regulation of cellular process#GO:0048522;cellular localization#GO:0051641;positive regulation of signaling#GO:0023056;protein transport#GO:0015031;protein import into nucleus#GO:0006606;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;establishment of protein localization#GO:0045184;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987 transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;nucleus#GO:0005634;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;ER to Golgi transport vesicle membrane#GO:0012507;intracellular membrane-bounded organelle#GO:0043231;nuclear pore outer ring#GO:0031080;vesicle#GO:0031982;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasm#GO:0005737;vesicle coat#GO:0030120;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular vesicle#GO:0097708;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000041726.1|UniProtKB=K7E3V0 K7E3V0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000051307.1|UniProtKB=A0A5F8GS66 A0A5F8GS66 PTHR12876:SF26 N4BP1-RELATED NEDD4-BINDING PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519 post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of protein ubiquitination#GO:0031396;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of protein modification process#GO:0031399;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA stability#GO:0043487;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of RNA metabolic process#GO:0051252;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;positive regulation of RNA metabolic process#GO:0051254;negative regulation of proteasomal protein catabolic process#GO:1901799;positive regulation of mRNA metabolic process#GO:1903313;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;regulation of protein metabolic process#GO:0051246;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of protein catabolic process#GO:0042177;negative regulation of protein ubiquitination#GO:0031397;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nuclear body#GO:0016604;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000012605.4|UniProtKB=F6PI60 F6PI60 PTHR19256:SF71 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA CONSTANT 1-RELATED immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000002967.4|UniProtKB=F6Q5C2 F6Q5C2 ANKDD1B PTHR24125:SF1 ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1B MONDO|Ensembl=ENSMODG00000027400.2|UniProtKB=K7E2R2 K7E2R2 PTHR24027:SF78 CADHERIN-23 CADHERIN-LIKE PROTEIN 26 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;cell migration#GO:0016477;cell motility#GO:0048870 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898 cell adhesion molecule#PC00069;cadherin#PC00057 MONDO|Ensembl=ENSMODG00000002299.3|UniProtKB=A0A5F8HFV8 A0A5F8HFV8 PHLPP2 PTHR45752:SF10 LEUCINE-RICH REPEAT-CONTAINING PH DOMAIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN PHOSPHATASE 2 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000043612.1|UniProtKB=A0A5F8HEZ4 A0A5F8HEZ4 SCAMP4 PTHR10687:SF11 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 4 exocytosis#GO:0006887;secretion by cell#GO:0032940;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;transport#GO:0006810;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;vesicle membrane#GO:0012506;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000006539.3|UniProtKB=F7BV95 F7BV95 SUPT16H PTHR13980:SF15 CDC68 RELATED FACT COMPLEX SUBUNIT SPT16 nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;protein carrier activity#GO:0140597;chromatin binding#GO:0003682;molecular carrier activity#GO:0140104;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;chromatin organization#GO:0006325;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467 chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromosome#GO:0005694;organelle lumen#GO:0043233;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000017419.3|UniProtKB=F7AIV7 F7AIV7 PTHR12682:SF11 ARCHEASE TRNA-SPLICING LIGASE-ACTIVATING FACTOR ARCHEASE intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000006570.3|UniProtKB=F7B3F6 F7B3F6 ZBTB18 PTHR24394:SF18 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 18 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002596.3|UniProtKB=F7G4X2 F7G4X2 NDUFB7 PTHR20900:SF0 NADH:UBIQUINONE OXIDOREDUCTASE B18-LIKE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 7 membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000020649.4|UniProtKB=F7E6C1 F7E6C1 PTHR11679:SF71 VESICLE PROTEIN SORTING-ASSOCIATED SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 2 vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000016664.4|UniProtKB=F7G704 F7G704 PTHR11849:SF30 ETS ETS TRANSLOCATION VARIANT 3 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 MONDO|Ensembl=ENSMODG00000044213.1|UniProtKB=A0A5F8H6W9 A0A5F8H6W9 PTHR36129:SF2 ORGANIC SOLUTE TRANSPORTER SUBUNIT BETA-RELATED RICIN B LECTIN DOMAIN-CONTAINING PROTEIN transporter#PC00227 MONDO|Ensembl=ENSMODG00000002085.4|UniProtKB=F6UZ74 F6UZ74 GDF10 PTHR11848:SF145 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 10 cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;cell surface receptor signaling pathway#GO:0007166;positive regulation of developmental process#GO:0051094;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;signaling#GO:0023052 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000045955.1|UniProtKB=A0A5F8G351 A0A5F8G351 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009882.4|UniProtKB=A0A5F8H1M7 A0A5F8H1M7 POC1B PTHR44019:SF1 WD REPEAT-CONTAINING PROTEIN 55 POC1 CENTRIOLAR PROTEIN HOMOLOG B cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000048385.1|UniProtKB=A0A5F8G5K3 A0A5F8G5K3 KIAA0040 PTHR40382:SF1 FAMILY NOT NAMED RIKEN CDNA 4930523C07 GENE MONDO|Ensembl=ENSMODG00000010165.5|UniProtKB=F6TAJ9 F6TAJ9 PTHR23327:SF41 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 3 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000024295.2|UniProtKB=F7F0L7 F7F0L7 LOC100024515 PTHR48018:SF85 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M10 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000042754.1|UniProtKB=F6PW45 F6PW45 LOC100018312 PTHR11414:SF20 CYSTATIN FAMILY MEMBER CYSTATIN-A enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000036651.1|UniProtKB=A0A5F8GYV7 A0A5F8GYV7 PCP2 PTHR47503:SF1 PURKINJE CELL PROTEIN 2 PURKINJE CELL PROTEIN 2 HOMOLOG guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 MONDO|Ensembl=ENSMODG00000002972.4|UniProtKB=F6Q5A0 F6Q5A0 PTHR12876:SF36 N4BP1-RELATED RIBONUCLEASE ZC3H12C-RELATED RNA binding#GO:0003723;nuclease activity#GO:0004518;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000000506.3|UniProtKB=F6Y650 F6Y650 INO80C PTHR31200:SF1 INO80 COMPLEX SUBUNIT C INO80 COMPLEX SUBUNIT C cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840 INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;Ino80 complex#GO:0031011;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974 MONDO|Ensembl=ENSMODG00000018097.4|UniProtKB=F7FFR4 F7FFR4 TMPRSS7 PTHR24253:SF196 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 7 catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000006374.3|UniProtKB=F7GCQ9 F7GCQ9 VSX2 PTHR46892:SF1 VISUAL SYSTEM HOMEOBOX 2 VISUAL SYSTEM HOMEOBOX 2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000015709.5|UniProtKB=F6PIN7 F6PIN7 HIRIP3 PTHR15410:SF2 HIRA-INTERACTING PROTEIN 3 HIRA-INTERACTING PROTEIN 3 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000013703.4|UniProtKB=A0A5F8H7P7 A0A5F8H7P7 POR PTHR19384:SF17 NITRIC OXIDE SYNTHASE-RELATED NADPH--CYTOCHROME P450 REDUCTASE ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;oxidoreductase activity, acting on NAD(P)H#GO:0016651;carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>P450 reductase#P04605 MONDO|Ensembl=ENSMODG00000021454.4|UniProtKB=A0A5F8G3N8 A0A5F8G3N8 LAMA1 PTHR10574:SF409 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-1 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;camera-type eye development#GO:0043010;visual system development#GO:0150063;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;sensory organ development#GO:0007423;plasma membrane bounded cell projection organization#GO:0120036;tube development#GO:0035295;tissue development#GO:0009888;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;eye development#GO:0001654;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;circulatory system development#GO:0072359;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;blood vessel morphogenesis#GO:0048514;cell projection morphogenesis#GO:0048858;vasculature development#GO:0001944;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular process#GO:0009987;neuron projection development#GO:0031175;sensory system development#GO:0048880 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 MONDO|Ensembl=ENSMODG00000039172.1|UniProtKB=A0A5F8GEQ6 A0A5F8GEQ6 TMPPE PTHR31302:SF0 TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN-RELATED TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN MONDO|Ensembl=ENSMODG00000018445.3|UniProtKB=F7CUH9 F7CUH9 WDR53 PTHR44666:SF1 WD REPEAT-CONTAINING PROTEIN 53 WD REPEAT-CONTAINING PROTEIN 53 MONDO|Ensembl=ENSMODG00000010529.4|UniProtKB=F7CND5 F7CND5 LOC100032991 PTHR11905:SF158 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 18 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 sex differentiation#GO:0007548;cellular process#GO:0009987;male gonad development#GO:0008584;single fertilization#GO:0007338;gonad development#GO:0008406;multicellular organismal process#GO:0032501;male sex differentiation#GO:0046661;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;sperm-egg recognition#GO:0035036;development of primary male sexual characteristics#GO:0046546;metabolic process#GO:0008152;cell-cell recognition#GO:0009988;animal organ development#GO:0048513;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;reproductive structure development#GO:0048608;fertilization#GO:0009566;cell recognition#GO:0008037;cell adhesion#GO:0007155;sexual reproduction#GO:0019953;animal gross anatomical part developmental process#GO:0160108;proteolysis#GO:0006508;reproductive system development#GO:0061458;system development#GO:0048731;binding of sperm to zona pellucida#GO:0007339;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000017303.2|UniProtKB=F6S483 F6S483 SLC39A1 PTHR11040:SF58 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP1 monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000036809.1|UniProtKB=A0A5F8HK16 A0A5F8HK16 PTHR23239:SF96 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 9 structural molecule activity#GO:0005198 cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;morphogenesis of an epithelium#GO:0002009;developmental process#GO:0032502 intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000050562.1|UniProtKB=A0A5F8H5W8 A0A5F8H5W8 TBCA PTHR21500:SF0 TUBULIN-SPECIFIC CHAPERONE A TUBULIN-SPECIFIC CHAPERONE A tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 chaperonin#PC00073 MONDO|Ensembl=ENSMODG00000028308.2|UniProtKB=K7E224 K7E224 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000005484.5|UniProtKB=F7CFV3 F7CFV3 TBP PTHR10126:SF42 TATA-BOX BINDING PROTEIN TATA-BOX-BINDING PROTEIN DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription initiation#GO:0006352;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;Huntington disease#P00029>TBP#P00779 MONDO|Ensembl=ENSMODG00000025545.2|UniProtKB=F6UJ77 F6UJ77 PTHR23320:SF170 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 18-LIKE transporter#PC00227 MONDO|Ensembl=ENSMODG00000036454.1|UniProtKB=A0A5F8GUW7 A0A5F8GUW7 KRT18 PTHR23239:SF349 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 18 cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;intermediate filament-based process#GO:0045103;organelle organization#GO:0006996 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000020050.3|UniProtKB=F6ZGD2 F6ZGD2 LOC100021065 PTHR48018:SF109 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8U3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010497.4|UniProtKB=F7EAF5 F7EAF5 CDK14 PTHR24056:SF154 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 14 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;cyclin binding#GO:0030332;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;cyclin-dependent protein kinase activity#GO:0097472;cyclin-dependent protein serine/threonine kinase activity#GO:0004693 cell cycle phase transition#GO:0044770;G2/M transition of mitotic cell cycle#GO:0000086;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G2/M phase transition#GO:0044839;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;protein kinase complex#GO:1902911;transferase complex#GO:1990234 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000016548.3|UniProtKB=F7E7P4 F7E7P4 RASSF8 PTHR15286:SF9 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 8 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018232.3|UniProtKB=F6PGC0 F6PGC0 RABL3 PTHR24073:SF128 DRAB5-RELATED RAB-LIKE PROTEIN 3 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000013650.4|UniProtKB=K7DZ89 K7DZ89 ZP3 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 extracellular matrix structural constituent#GO:0005201;enzyme binding#GO:0019899;binding#GO:0005488;structural molecule activity#GO:0005198;protein binding#GO:0005515 cell-cell recognition#GO:0009988;cellular developmental process#GO:0048869;developmental process#GO:0032502;sperm-egg recognition#GO:0035036;biological regulation#GO:0065007;oogenesis#GO:0048477;regulation of reproductive process#GO:2000241;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;single fertilization#GO:0007338;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;binding of sperm to zona pellucida#GO:0007339;sexual reproduction#GO:0019953;cell recognition#GO:0008037;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;fertilization#GO:0009566;cell differentiation#GO:0030154;gamete generation#GO:0007276;regulation of biological process#GO:0050789;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 MONDO|Ensembl=ENSMODG00000020484.4|UniProtKB=F6UNX3 F6UNX3 CCDC59 PTHR15657:SF1 THYROID TRANSCRIPTION FACTOR 1-ASSOCIATED PROTEIN 26 THYROID TRANSCRIPTION FACTOR 1-ASSOCIATED PROTEIN 26 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000018925.5|UniProtKB=F7GJV8 F7GJV8 TRPC3 PTHR10117:SF8 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 3 anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873 calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;single fertilization#GO:0007338;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;sexual reproduction#GO:0019953;calcium ion homeostasis#GO:0055074;reproductive process#GO:0022414;fertilization#GO:0009566;homeostatic process#GO:0042592;metal ion transport#GO:0030001;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588 cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 MONDO|Ensembl=ENSMODG00000010224.4|UniProtKB=A0A5F8HJV6 A0A5F8HJV6 ZRANB1 PTHR13367:SF28 UBIQUITIN THIOESTERASE UBIQUITIN THIOESTERASE ZRANB1 hydrolase activity#GO:0016787;protein binding#GO:0005515;deubiquitinase activity#GO:0101005;modification-dependent protein binding#GO:0140030;binding#GO:0005488;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;polyubiquitin modification-dependent protein binding#GO:0031593;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of Wnt signaling pathway#GO:0030177;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of Wnt signaling pathway#GO:0030111;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification process#GO:0036211;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;modification-dependent protein catabolic process#GO:0019941;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000004795.3|UniProtKB=F6VMB3 F6VMB3 EBAG9 PTHR15208:SF2 RECEPTOR-BINDING CANCER ANTIGEN EXPRESSED ON SISO CELLS CANCER ASSOCIATED SURFACE ANTIGEN RCAS1 ESTROGEN RECEPTOR-BINDING FRAGMENT- ASSOCIATED GENE 9 PROTEIN RECEPTOR-BINDING CANCER ANTIGEN EXPRESSED ON SISO CELLS protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of secretion#GO:0051046;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708 MONDO|Ensembl=ENSMODG00000014754.4|UniProtKB=F6YMC4 F6YMC4 LOC100013494 PTHR24291:SF198 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4F11 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000006692.4|UniProtKB=A0A5F8H6E8 A0A5F8H6E8 PLG PTHR24261:SF13 PLASMINOGEN-RELATED PLASMINOGEN signaling receptor binding#GO:0005102;binding#GO:0005488;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of blood coagulation#GO:0030193;regulation of body fluid levels#GO:0050878;regulation of wound healing#GO:0061041;proteolysis#GO:0006508;negative regulation of hemostasis#GO:1900047;negative regulation of coagulation#GO:0050819;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;regulation of response to wounding#GO:1903034;negative regulation of wound healing#GO:0061045;regulation of hemostasis#GO:1900046;cellular process#GO:0009987;fibrinolysis#GO:0042730;regulation of coagulation#GO:0050818;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;metabolic process#GO:0008152;negative regulation of blood coagulation#GO:0030195;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;negative regulation of response to wounding#GO:1903035 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;serine protease#PC00203 Blood coagulation#P00011>Plasmin#P00415;Blood coagulation#P00011>Plasminogen#P00408;Plasminogen activating cascade#P00050>Plasminogen#P01255;Plasminogen activating cascade#P00050>Plasmin#P01246 MONDO|Ensembl=ENSMODG00000037804.1|UniProtKB=A0A5F8GRB7 A0A5F8GRB7 MORN5 PTHR46437:SF1 MORN REPEAT-CONTAINING PROTEIN 5 MORN REPEAT-CONTAINING PROTEIN 5 MONDO|Ensembl=ENSMODG00000025005.3|UniProtKB=F6TCD6 F6TCD6 C10orf53 PTHR28448:SF1 UPF0728 PROTEIN C10ORF53 UPF0728 PROTEIN C10ORF53 MONDO|Ensembl=ENSMODG00000041163.1|UniProtKB=A0A5F8HHW0 A0A5F8HHW0 PTHR24393:SF100 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 345-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018494.4|UniProtKB=F7BRL6 F7BRL6 RAB6B PTHR24073:SF343 DRAB5-RELATED RAS-RELATED PROTEIN RAB-6B hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 protein localization to membrane#GO:0072657;intra-Golgi vesicle-mediated transport#GO:0006891;protein localization to organelle#GO:0033365;cytosolic transport#GO:0016482;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000000088.4|UniProtKB=A0A5F8GW32 A0A5F8GW32 MCU PTHR13462:SF16 CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262;secondary active transmembrane transporter activity#GO:0015291 transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;mitochondrial calcium ion homeostasis#GO:0051560;homeostatic process#GO:0042592;metal ion transport#GO:0030001 organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;calcium channel complex#GO:0034704;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;cation channel complex#GO:0034703;inner mitochondrial membrane protein complex#GO:0098800;transporter complex#GO:1990351;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000001987.3|UniProtKB=F6RIC0 F6RIC0 ZNF282 PTHR24381:SF269 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 398 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014891.4|UniProtKB=F7GGB0 F7GGB0 AGPAT1 PTHR10434:SF65 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE ALPHA acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000042381.1|UniProtKB=A0A5F8GAI8 A0A5F8GAI8 AP3S2 PTHR11753:SF10 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-3 COMPLEX SUBUNIT SIGMA-2 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000011537.5|UniProtKB=F6QWV3 F6QWV3 TOPBP1 PTHR13561:SF20 DNA REPLICATION REGULATOR DPB11-RELATED DNA TOPOISOMERASE 2-BINDING PROTEIN 1 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000015857.4|UniProtKB=F7F0C6 F7F0C6 EFR3B PTHR12444:SF4 PROTEIN EFR3 HOMOLOG CMP44E PROTEIN EFR3 HOMOLOG B protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 cellular process#GO:0009987;protein localization to plasma membrane#GO:0072659;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000018861.4|UniProtKB=F7DVI2 F7DVI2 ADGRF4 PTHR45813:SF1 IG-LIKE DOMAIN-CONTAINING PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR F4 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000006327.4|UniProtKB=F7AGY7 F7AGY7 PTPN5 PTHR46198:SF1 PROTEIN-TYROSINE-PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 5 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000013142.4|UniProtKB=F7AZC2 F7AZC2 CHD9 PTHR46850:SF1 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9 ATP-DEPENDENT CHROMATIN REMODELER CHD9 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000001148.3|UniProtKB=F7D4D2 F7D4D2 ZNRF4 PTHR22765:SF347 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ZNRF4 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;biological regulation#GO:0065007 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000044001.1|UniProtKB=A0A5F8H241 A0A5F8H241 PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN antigen binding#GO:0003823;peptide binding#GO:0042277;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of leukocyte mediated immunity#GO:0002705 external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000043196.1|UniProtKB=A0A5F8H1W5 A0A5F8H1W5 PHKG1 PTHR44167:SF32 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED PHOSPHORYLASE KINASE catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000015372.4|UniProtKB=F6WH61 F6WH61 CYP27A1 PTHR24291:SF6 CYTOCHROME P450 FAMILY 4 STEROL 26-HYDROXYLASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395 primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;vitamin D metabolic process#GO:0042359;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>1alpha-Hydroxylase#P04603 MONDO|Ensembl=ENSMODG00000017267.4|UniProtKB=F6T3Q1 F6T3Q1 AIG1 PTHR10989:SF11 ANDROGEN-INDUCED PROTEIN 1-RELATED ANDROGEN-INDUCED GENE 1 PROTEIN hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 monocarboxylic acid catabolic process#GO:0072329;long-chain fatty acid metabolic process#GO:0001676;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436 MONDO|Ensembl=ENSMODG00000011993.4|UniProtKB=F7B995 F7B995 SEMA4G PTHR11036:SF17 SEMAPHORIN SEMAPHORIN-4G binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon guidance#GO:0007411;axon development#GO:0061564;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;regulation of cellular process#GO:0050794;chemotaxis#GO:0006935;system development#GO:0048731;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;taxis#GO:0042330;response to chemical#GO:0042221;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000020997.4|UniProtKB=F6RJZ3 F6RJZ3 HEMK2 PTHR45875:SF1 METHYLTRANSFERASE N6AMT1 METHYLTRANSFERASE HEMK2 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 transferase complex#GO:1990234;catalytic complex#GO:1902494;methyltransferase complex#GO:0034708;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000013144.4|UniProtKB=A0A5F8G5J3 A0A5F8G5J3 CATSPERG PTHR14327:SF2 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT GAMMA CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT GAMMA-LIKE ISOFORM X1 cilium#GO:0005929;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000010515.4|UniProtKB=F7E9Q2 F7E9Q2 SERPINF1 PTHR11461:SF84 SERINE PROTEASE INHIBITOR, SERPIN PIGMENT EPITHELIUM-DERIVED FACTOR endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of multicellular organismal process#GO:0051239;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of angiogenesis#GO:0045765;negative regulation of angiogenesis#GO:0016525;regulation of anatomical structure morphogenesis#GO:0022603;regulation of vasculature development#GO:1901342 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000007975.4|UniProtKB=F7DQM9 F7DQM9 ARHGEF15 PTHR12845:SF7 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 15 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of actin filament-based process#GO:0032970 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000028341.2|UniProtKB=K7E613 K7E613 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000007051.4|UniProtKB=F6UFC7 F6UFC7 SLCO2B1 PTHR11388:SF87 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2B1 active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;basal part of cell#GO:0045178;apical plasma membrane#GO:0016324;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;apical part of cell#GO:0045177 transporter#PC00227 MONDO|Ensembl=ENSMODG00000009072.4|UniProtKB=A0A5F8G455 A0A5F8G455 NAV2 PTHR12784:SF6 STEERIN NEURON NAVIGATOR 2 multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;system development#GO:0048731;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 MONDO|Ensembl=ENSMODG00000003928.3|UniProtKB=F7GIY5 F7GIY5 BMP2 PTHR11848:SF143 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 2 cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular developmental process#GO:0048869;heart morphogenesis#GO:0003007;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;ossification#GO:0001503;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular process#GO:0009987;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;response to stimulus#GO:0050896;cell differentiation#GO:0030154;osteoblast differentiation#GO:0001649;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286;Gonadotropin-releasing hormone receptor pathway#P06664>BMP2/4/15#P06817 MONDO|Ensembl=ENSMODG00000019643.4|UniProtKB=A0A5F8GX12 A0A5F8GX12 CNTRL PTHR23159:SF17 CENTROSOMAL PROTEIN 2 ROOTLETIN microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;cellular process#GO:0009987;cell cycle process#GO:0022402;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010 centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000025644.3|UniProtKB=F6XVR8 F6XVR8 PTHR33722:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT DELTA-RELATED CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT DELTA reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell differentiation#GO:0030154;cell motility#GO:0048870;microtubule-based movement#GO:0007018;gamete generation#GO:0007276;anatomical structure maturation#GO:0071695;sperm motility#GO:0097722;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;cilium-dependent cell motility#GO:0060285;anatomical structure development#GO:0048856;cilium movement#GO:0003341;sexual reproduction#GO:0019953;cilium or flagellum-dependent cell motility#GO:0001539;spermatid development#GO:0007286;spermatid differentiation#GO:0048515;sperm capacitation#GO:0048240;developmental maturation#GO:0021700;male gamete generation#GO:0048232;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;microtubule-based process#GO:0007017;cell maturation#GO:0048469;cellular developmental process#GO:0048869;developmental process#GO:0032502;spermatogenesis#GO:0007283;flagellated sperm motility#GO:0030317 membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;9+2 motile cilium#GO:0097729;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;sperm principal piece#GO:0097228;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;transporter complex#GO:1990351;cation channel complex#GO:0034703;plasma membrane#GO:0005886;CatSper complex#GO:0036128;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;sperm flagellum#GO:0036126;cell periphery#GO:0071944;membrane#GO:0016020 voltage-gated ion channel#PC00241;transporter#PC00227 MONDO|Ensembl=ENSMODG00000009975.4|UniProtKB=H9H6C9 H9H6C9 DDX23 PTHR47958:SF56 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX23-RELATED RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000041553.1|UniProtKB=A0A5F8GGS2 A0A5F8GGS2 PTHR19229:SF274 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ABC-TYPE ORGANIC ANION TRANSPORTER ABCA8 ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000018774.4|UniProtKB=K7E1G2 K7E1G2 PRPF3 PTHR14212:SF0 U4/U6-ASSOCIATED RNA SPLICING FACTOR-RELATED U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP3 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 mRNA splicing#P00058>U6#P01473;mRNA splicing#P00058>U4#P01476 MONDO|Ensembl=ENSMODG00000004010.4|UniProtKB=F7D7C2 F7D7C2 ATP7A PTHR43520:SF29 ATP7, ISOFORM B COPPER-TRANSPORTING ATPASE 1 transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;cation binding#GO:0043169;copper ion binding#GO:0005507;transporter activity#GO:0005215;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;binding#GO:0005488;transition metal ion transmembrane transporter activity#GO:0046915;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;metal ion binding#GO:0046872;monoatomic cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;homeostatic process#GO:0042592;copper ion transmembrane transport#GO:0035434;intracellular monoatomic ion homeostasis#GO:0006873;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000017180.1|UniProtKB=F6XYL1 F6XYL1 S100G PTHR11639:SF73 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-G protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 sarcoplasm#GO:0016528;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;sarcoplasmic reticulum#GO:0016529;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000047227.1|UniProtKB=A0A5F8H9T0 A0A5F8H9T0 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000043330.1|UniProtKB=A0A5F8GZQ5 A0A5F8GZQ5 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000044384.1|UniProtKB=A0A5F8G8C3 A0A5F8G8C3 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000007551.1|UniProtKB=F6V2S3 F6V2S3 OTUD6B PTHR12419:SF21 OTU DOMAIN CONTAINING PROTEIN DEUBIQUITINASE OTUD6B hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000015358.2|UniProtKB=F6WXH1 F6WXH1 LOC100022354 PTHR48018:SF57 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016536.2|UniProtKB=F7E844 F7E844 ELOB PTHR13248:SF4 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2 ELONGIN-B transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of gene silencing by regulatory ncRNA#GO:0060966;negative regulation of metabolic process#GO:0009892;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional gene silencing#GO:0016441;protein metabolic process#GO:0019538;positive regulation of biosynthetic process#GO:0009891 organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Cul2-RING ubiquitin ligase complex#GO:0031462;Cul5-RING ubiquitin ligase complex#GO:0031466;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000050055.1|UniProtKB=A0A5F8HEH3 A0A5F8HEH3 YEATS4 PTHR23195:SF15 YEATS DOMAIN YEATS DOMAIN-CONTAINING PROTEIN 4 binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000002189.4|UniProtKB=F6YID2 F6YID2 FLNB PTHR38537:SF7 JITTERBUG, ISOFORM N FILAMIN-B Integrin signalling pathway#P00034>Filamin#P00914 MONDO|Ensembl=ENSMODG00000008565.4|UniProtKB=F7CXA0 F7CXA0 LRRC9 PTHR46652:SF3 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 MONDO|Ensembl=ENSMODG00000002797.4|UniProtKB=F7EJK8 F7EJK8 LPGAT1 PTHR10983:SF2 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED ACYL-COA:LYSOPHOSPHATIDYLGLYCEROL ACYLTRANSFERASE 1 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000044488.1|UniProtKB=A0A5F8HCU4 A0A5F8HCU4 PTHR24249:SF79 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 9 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000004102.4|UniProtKB=F6VFD0 F6VFD0 FZD4 PTHR11309:SF23 FRIZZLED FRIZZLED-4 signaling receptor activity#GO:0038023;protein binding#GO:0005515;molecular transducer activity#GO:0060089;Wnt-protein binding#GO:0017147;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cellular process#GO:0009987;signal transduction#GO:0007165;sensory system development#GO:0048880;retina development in camera-type eye#GO:0060041;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;sensory organ development#GO:0007423;vasculature development#GO:0001944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;non-canonical Wnt signaling pathway#GO:0035567;visual system development#GO:0150063;signaling#GO:0023052;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;circulatory system development#GO:0072359;response to stimulus#GO:0050896;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475 MONDO|Ensembl=ENSMODG00000010196.2|UniProtKB=F6STA6 F6STA6 POLB PTHR11276:SF42 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA POLYMERASE BETA catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;DNA-directed DNA polymerase activity#GO:0003887 DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000004968.2|UniProtKB=F7FL66 F7FL66 WBP1 PTHR16209:SF5 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 WW DOMAIN-BINDING PROTEIN 1 MONDO|Ensembl=ENSMODG00000003594.2|UniProtKB=F7FBJ1 F7FBJ1 PTHR15225:SF4 INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN N-MYC-INTERACTOR cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000000340.4|UniProtKB=A0A5F8G991 A0A5F8G991 HIBADH PTHR22981:SF85 3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED 3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000041122.1|UniProtKB=A0A5F8GUQ3 A0A5F8GUQ3 PTHR47564:SF1 CYSTEINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 CYSTEINE-RICH TRANSMEMBRANE MODULE-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000018288.4|UniProtKB=F6PWR7 F6PWR7 ILDR1 PTHR15923:SF3 TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING RECEPTOR 1 cargo receptor activity#GO:0038024 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000047238.1|UniProtKB=A0A5F8GF02 A0A5F8GF02 CRX PTHR45793:SF22 HOMEOBOX PROTEIN CONE-ROD HOMEOBOX PROTEIN transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000000320.3|UniProtKB=F6VUE3 F6VUE3 PKDCC PTHR46448:SF3 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN EXTRACELLULAR TYROSINE-PROTEIN KINASE PKDCC MONDO|Ensembl=ENSMODG00000019915.4|UniProtKB=F6VPH5 F6VPH5 KBTBD4 PTHR47195:SF1 KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 4 KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 4 MONDO|Ensembl=ENSMODG00000002364.4|UniProtKB=F7GDK6 F7GDK6 PTHR12011:SF455 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E3 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014009.4|UniProtKB=F6VQE9 F6VQE9 PTHR16213:SF78 SELENOPROTEIN N SELENOPROTEIN N regulation of monoatomic cation transmembrane transport#GO:1904062;developmental process#GO:0032502;monoatomic cation homeostasis#GO:0055080;cellular developmental process#GO:0048869;skeletal muscle tissue development#GO:0007519;regulation of monoatomic ion transport#GO:0043269;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;muscle cell development#GO:0055001;regulation of transmembrane transport#GO:0034762;muscle cell differentiation#GO:0042692;regulation of metal ion transport#GO:0010959;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;muscle organ development#GO:0007517;striated muscle tissue development#GO:0014706;chemical homeostasis#GO:0048878;animal organ development#GO:0048513;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of release of sequestered calcium ion into cytosol#GO:0051279;striated muscle cell differentiation#GO:0051146;monoatomic ion homeostasis#GO:0050801;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;striated muscle cell development#GO:0055002;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cell development#GO:0048468 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000020529.4|UniProtKB=A0A5F8GDH0 A0A5F8GDH0 TBC1D1 PTHR22957:SF204 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 1 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000005974.4|UniProtKB=F6VZA7 F6VZA7 PTHR10194:SF52 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN NGAP GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 MONDO|Ensembl=ENSMODG00000000338.4|UniProtKB=F6YU46 F6YU46 PTHR12151:SF4 ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER CYTOCHROME C OXIDASE ASSEMBLY FACTOR SCO1 mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617 oxidoreductase#PC00176;oxidase#PC00175;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000015624.3|UniProtKB=F7FEW2 F7FEW2 PTHR34256:SF1 UPF0561 PROTEIN C2ORF68 UPF0561 PROTEIN C2ORF68 MONDO|Ensembl=ENSMODG00000002007.3|UniProtKB=F6RHC2 F6RHC2 LYSMD2 PTHR20932:SF4 LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 2-RELATED MONDO|Ensembl=ENSMODG00000028923.2|UniProtKB=K7E336 K7E336 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000043290.1|UniProtKB=A0A5F8GTU2 A0A5F8GTU2 TMPRSS15 PTHR24253:SF71 TRANSMEMBRANE PROTEASE SERINE ENTEROPEPTIDASE serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;membrane#GO:0016020 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000008029.4|UniProtKB=F7CKP3 F7CKP3 PSPC1 PTHR23189:SF14 RNA RECOGNITION MOTIF-CONTAINING PARASPECKLE COMPONENT 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000014012.4|UniProtKB=F6VQC9 F6VQC9 F9 PTHR24278:SF31 COAGULATION FACTOR COAGULATION FACTOR IX hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 coagulation#GO:0050817;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;response to wounding#GO:0009611;response to stress#GO:0006950;biological regulation#GO:0065007;biosynthetic process#GO:0009058;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;gene expression#GO:0010467;metabolic process#GO:0008152;blood coagulation#GO:0007596;macromolecule metabolic process#GO:0043170;zymogen activation#GO:0031638;hemostasis#GO:0007599;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;proteolysis#GO:0006508;wound healing#GO:0042060;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 Blood coagulation#P00011>FIX#P00444;Blood coagulation#P00011>FIXa#P00422;Blood coagulation#P00011>FXIa#P00434;Blood coagulation#P00011>FXI#P00460 MONDO|Ensembl=ENSMODG00000007941.3|UniProtKB=F7G902 F7G902 HNRNPUL2 PTHR12381:SF66 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U-LIKE PROTEIN 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000017422.2|UniProtKB=A0A5F8GRG7 A0A5F8GRG7 PTHR11937:SF414 ACTIN ACTIN, CYTOPLASMIC 1 binding#GO:0005488;kinase binding#GO:0019900;structural constituent of cytoskeleton#GO:0005200;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell motility#GO:0048870;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 chromosome#GO:0005694;plasma membrane bounded cell projection#GO:0120025;catalytic complex#GO:1902494;axon#GO:0030424;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;H4 histone acetyltransferase complex#GO:1902562;cytoskeleton#GO:0005856;transferase complex#GO:1990234;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;actin cytoskeleton#GO:0015629;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;supramolecular fiber#GO:0099512;neuron projection#GO:0043005;chromatin#GO:0000785;supramolecular complex#GO:0099080;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin filament#GO:0005884;cell junction#GO:0030054;histone acetyltransferase complex#GO:0000123 actin and actin related protein#PC00039 Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470 MONDO|Ensembl=ENSMODG00000021181.2|UniProtKB=H9H7W4 H9H7W4 IFITM5 PTHR13999:SF10 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 5 multicellular organism development#GO:0007275;animal organ development#GO:0048513;developmental process#GO:0032502;bone mineralization#GO:0030282;tissue development#GO:0009888;multicellular organismal process#GO:0032501;bone development#GO:0060348;skeletal system morphogenesis#GO:0048705;system development#GO:0048731;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;biomineral tissue development#GO:0031214;animal gross anatomical part developmental process#GO:0160108;animal organ morphogenesis#GO:0009887;ossification#GO:0001503;anatomical structure morphogenesis#GO:0009653 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000005359.4|UniProtKB=F6YLF5 F6YLF5 ZFPM2 PTHR12958:SF5 FRIEND OF GATA2-RELATED ZINC FINGER PROTEIN ZFPM2 transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;heart development#GO:0007507;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000017907.4|UniProtKB=F7F330 F7F330 TRAF3IP2 PTHR34257:SF2 ADAPTER PROTEIN CIKS E3 UBIQUITIN LIGASE TRAF3IP2 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of canonical NF-kappaB signal transduction#GO:0043122;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;humoral immune response#GO:0006959;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000047651.1|UniProtKB=A0A5F8G9A1 A0A5F8G9A1 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015620.4|UniProtKB=F6YFQ8 F6YFQ8 KRTCAP3 PTHR31258:SF1 KERATINOCYTE-ASSOCIATED PROTEIN 3 KERATINOCYTE-ASSOCIATED PROTEIN 3 MONDO|Ensembl=ENSMODG00000017972.3|UniProtKB=A0A5F8H9U8 A0A5F8H9U8 C3AR1 PTHR24225:SF28 CHEMOTACTIC RECEPTOR C3A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 immune response-activating signaling pathway#GO:0002757;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;regulation of biological quality#GO:0065008;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000005371.4|UniProtKB=F6YL58 F6YL58 EMC3 PTHR13116:SF10 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3 molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597 membrane organization#GO:0061024;endomembrane system organization#GO:0010256;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;cellular process#GO:0009987;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein localization to organelle#GO:0033365;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668 membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000014307.4|UniProtKB=A0A5F8G3U2 A0A5F8G3U2 HDX PTHR11636:SF80 POU DOMAIN HIGHLY DIVERGENT HOMEOBOX sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000019863.4|UniProtKB=A0A5F8GHJ2 A0A5F8GHJ2 ALKBH3 PTHR31212:SF4 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3 macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000042197.1|UniProtKB=A0A5F8GPR3 A0A5F8GPR3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008243.3|UniProtKB=A0A5F8G5X5 A0A5F8G5X5 DPP3 PTHR23422:SF11 DIPEPTIDYL PEPTIDASE III-RELATED DIPEPTIDYL PEPTIDASE 3 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000015150.3|UniProtKB=F7CFT5 F7CFT5 BRCA1 PTHR13763:SF11 BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1 BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN damaged DNA binding#GO:0003684;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;nucleic acid binding#GO:0003676;binding#GO:0005488;ubiquitin-protein transferase activity#GO:0004842;DNA binding#GO:0003677 negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;negative regulation of cell cycle G2/M phase transition#GO:1902750;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic G2/M transition checkpoint#GO:0044818;regulation of mitotic cell cycle#GO:0007346;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;recombinational repair#GO:0000725 DNA repair complex#GO:1990391;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;condensed chromosome#GO:0000793;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000027341.2|UniProtKB=K7E4C4 K7E4C4 LOC103098366 PTHR15934:SF4 RNA 2',3'-CYCLIC PHOSPHODIESTERASE A-KINASE ANCHOR PROTEIN 7-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;protein kinase A regulatory subunit binding#GO:0034237;protein kinase A binding#GO:0051018;binding#GO:0005488 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000038234.1|UniProtKB=F7A6Z3 F7A6Z3 LOC100618683 PTHR26452:SF695 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000005981.4|UniProtKB=F6VIQ3 F6VIQ3 CFAP61 PTHR21178:SF8 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61 membrane-bounded organelle#GO:0043227;cilium#GO:0005929;9+2 motile cilium#GO:0097729;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000016273.4|UniProtKB=A0A5F8HDH9 A0A5F8HDH9 SI PTHR22762:SF66 ALPHA-GLUCOSIDASE SUCRASE-ISOMALTASE, INTESTINAL hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;alpha-glucosidase activity#GO:0090599;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;glucosidase activity#GO:0015926;catalytic activity#GO:0003824 glucosidase#PC00108 MONDO|Ensembl=ENSMODG00000044563.1|UniProtKB=A0A5F8GQC7 A0A5F8GQC7 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000048809.1|UniProtKB=A0A5F8GEW7 A0A5F8GEW7 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000016691.2|UniProtKB=F7DLW2 F7DLW2 PPP2R2A PTHR11871:SF2 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B ALPHA ISOFORM enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;cytosol#GO:0005829 protein modifying enzyme#PC00260;protein phosphatase#PC00195 FGF signaling pathway#P00021>PP2A#P00629 MONDO|Ensembl=ENSMODG00000045574.1|UniProtKB=F7FTF1 F7FTF1 monDomV1R1227 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014850.4|UniProtKB=F7BZ08 F7BZ08 SH3GL2 PTHR14167:SF50 SH3 DOMAIN-CONTAINING ENDOPHILIN-A1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;endocytosis#GO:0006897;synaptic vesicle endocytosis#GO:0048488;cellular component organization#GO:0016043 glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cytosol#GO:0005829;presynapse#GO:0098793;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000012920.3|UniProtKB=A0A5F8GGQ7 A0A5F8GGQ7 LOC103100274 PTHR16399:SF18 GASDERMIN GASDERMIN-A transporter#PC00227 MONDO|Ensembl=ENSMODG00000012112.5|UniProtKB=F7FU84 F7FU84 DNAH7 PTHR10676:SF310 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 7 cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;protein binding#GO:0005515;microtubule motor activity#GO:0003777;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657 microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;inner dynein arm assembly#GO:0036159;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;protein-containing complex assembly#GO:0065003;sperm motility#GO:0097722;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;gamete generation#GO:0007276;developmental process#GO:0032502;spermatogenesis#GO:0007283;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;cellular developmental process#GO:0048869;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;sexual reproduction#GO:0019953;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870 axonemal dynein complex#GO:0005858;dynein complex#GO:0030286;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;catalytic complex#GO:1902494;cilium#GO:0005929;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;inner dynein arm#GO:0036156;membraneless organelle#GO:0043228 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000009897.4|UniProtKB=A0A5F8GLW2 A0A5F8GLW2 PSD3 PTHR10663:SF337 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 3 cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;leading edge membrane#GO:0031256;ruffle membrane#GO:0032587;cell projection membrane#GO:0031253;ruffle#GO:0001726 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000013861.4|UniProtKB=A0A5F8H2H3 A0A5F8H2H3 SRRM1 PTHR23148:SF0 SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN SERINE_ARGININE REPETITIVE MATRIX PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000006625.4|UniProtKB=F7GEP4 F7GEP4 CES2.1 PTHR11559:SF436 CARBOXYLESTERASE CARBOXYLIC ESTER HYDROLASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 esterase#PC00097 MONDO|Ensembl=ENSMODG00000001691.4|UniProtKB=F6S7E7 F6S7E7 NPAS2 PTHR46055:SF1 CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT NEURONAL PAS DOMAIN-CONTAINING PROTEIN 2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;circadian rhythm#GO:0007623;regulation of DNA-templated transcription#GO:0006355;rhythmic process#GO:0048511;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;circadian regulation of gene expression#GO:0032922 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000016108.3|UniProtKB=F7EAY2 F7EAY2 IGFALS PTHR24373:SF285 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN COMPLEX ACID LABILE SUBUNIT signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017397.3|UniProtKB=A0A5F8GRQ2 A0A5F8GRQ2 S100A4 PTHR11639:SF51 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A4 calcium ion binding#GO:0005509;ion binding#GO:0043167;signaling receptor binding#GO:0005102;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872 positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000006908.3|UniProtKB=F6PT66 F6PT66 PTHR11437:SF24 RIBONUCLEASE RIBONUCLEASE PANCREATIC catalytic activity, acting on RNA#GO:0140098;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;defense response#GO:0006952;response to external stimulus#GO:0009605 endoribonuclease#PC00094;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000015058.3|UniProtKB=A0A5F8GIK0 A0A5F8GIK0 STK11IP PTHR15454:SF75 NISCHARIN RELATED SERINE_THREONINE-PROTEIN KINASE 11-INTERACTING PROTEIN scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000049837.1|UniProtKB=A0A5F8HGK5 A0A5F8HGK5 ZFP91 PTHR46179:SF11 ZINC FINGER PROTEIN E3 UBIQUITIN-PROTEIN LIGASE ZFP91 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018871.3|UniProtKB=F7DAP3 F7DAP3 PSMB4 PTHR11599:SF5 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-4 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;nucleus#GO:0005634;proteasome complex#GO:0000502;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 MONDO|Ensembl=ENSMODG00000036521.1|UniProtKB=A0A5F8HFV9 A0A5F8HFV9 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000027511.1|UniProtKB=K7E1L0 K7E1L0 LOC103093126 PTHR45617:SF168 LEUCINE RICH REPEAT FAMILY PROTEIN RETICULON 4 RECEPTOR LIKE 2 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000009160.4|UniProtKB=F7FIB9 F7FIB9 MUS81 PTHR13451:SF0 CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT MUS81 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097 macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;mitotic cell cycle process#GO:1903047;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA damage checkpoint signaling#GO:0000077;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;DNA integrity checkpoint signaling#GO:0031570;double-strand break repair via break-induced replication#GO:0000727;resolution of meiotic recombination intermediates#GO:0000712;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;cell communication#GO:0007154;organelle fission#GO:0048285;intracellular signal transduction#GO:0035556;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;sexual reproduction#GO:0019953;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;homologous recombination#GO:0035825;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reciprocal homologous recombination#GO:0140527;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;organelle organization#GO:0006996;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;negative regulation of mitotic cell cycle#GO:0045930;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;meiosis I#GO:0007127;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;meiotic cell cycle process#GO:1903046;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endonuclease complex#GO:1905348;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000023439.3|UniProtKB=F6XB00 F6XB00 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009479.3|UniProtKB=F7FNJ8 F7FNJ8 PTHR13218:SF8 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11 transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 MONDO|Ensembl=ENSMODG00000014304.4|UniProtKB=F6W4P8 F6W4P8 PXDN PTHR11475:SF75 OXIDASE/PEROXIDASE PEROXIDASIN HOMOLOG oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;extracellular matrix assembly#GO:0085029;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 MONDO|Ensembl=ENSMODG00000018564.4|UniProtKB=F7FRS4 F7FRS4 NME9 PTHR46135:SF3 NME/NM23 FAMILY MEMBER 8 NME_NM23 FAMILY MEMBER 8 MONDO|Ensembl=ENSMODG00000002224.3|UniProtKB=F7DFY5 F7DFY5 LOC100017379 PTHR10926:SF1 CELL CYCLE CONTROL PROTEIN 50 CELL CYCLE CONTROL PROTEIN 50C enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;biological regulation#GO:0065007;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000004438.3|UniProtKB=F6RTX7 F6RTX7 JPH3 PTHR23085:SF7 GH28348P JUNCTOPHILIN-3 regulation of signaling#GO:0023051;regulation of synaptic plasticity#GO:0048167;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;sarcoplasm#GO:0016528;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000001250.4|UniProtKB=F7CJ84 F7CJ84 TMEM232 PTHR28651:SF1 TRANSMEMBRANE PROTEIN 232 TRANSMEMBRANE PROTEIN 232 MONDO|Ensembl=ENSMODG00000020423.4|UniProtKB=A0A5F8HI07 A0A5F8HI07 CCBE1 PTHR24034:SF76 EGF-LIKE DOMAIN-CONTAINING PROTEIN COLLAGEN AND CALCIUM-BINDING EGF DOMAIN-CONTAINING PROTEIN 1 anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organismal process#GO:0032501;circulatory system development#GO:0072359;anatomical structure morphogenesis#GO:0009653 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000012696.3|UniProtKB=F6UYN3 F6UYN3 C19orf12 PTHR31493:SF1 NAZO FAMILY MEMBER PROTEIN C19ORF12 monoatomic ion homeostasis#GO:0050801;autophagy#GO:0006914;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;metabolic process#GO:0008152;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;catabolic process#GO:0009056;mitochondrial calcium ion homeostasis#GO:0051560;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;process utilizing autophagic mechanism#GO:0061919;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740 MONDO|Ensembl=ENSMODG00000010642.4|UniProtKB=F7D4T6 F7D4T6 HES6 PTHR10985:SF11 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION COFACTOR HES-6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of neurogenesis#GO:0050767;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000041244.1|UniProtKB=A0A5F8GX85 A0A5F8GX85 LOC100025415 PTHR26452:SF52 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000029684.2|UniProtKB=K7E2K0 K7E2K0 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000037347.1|UniProtKB=A0A5F8HF43 A0A5F8HF43 NEU4 PTHR10628:SF22 SIALIDASE SIALIDASE-4 catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 ceramide metabolic process#GO:0006672;carbohydrate catabolic process#GO:0016052;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;glycolipid metabolic process#GO:0006664;oligosaccharide catabolic process#GO:0009313;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;oligosaccharide metabolic process#GO:0009311;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042 lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;lysosome#GO:0005764 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000006554.5|UniProtKB=F7BUY7 F7BUY7 LRRC47 PTHR10947:SF3 PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000014940.4|UniProtKB=A0A5F8G5C2 A0A5F8G5C2 PTHR11991:SF23 TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 negative regulation of programmed cell death#GO:0043069;regulation of metabolic process#GO:0019222;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of signaling#GO:0023057;negative regulation of catabolic process#GO:0009895;negative regulation of cell communication#GO:0010648 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000004127.4|UniProtKB=F6UWB1 F6UWB1 PTHR12489:SF20 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 7 PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000040232.1|UniProtKB=K7E2A5 K7E2A5 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000002663.4|UniProtKB=F7DI29 F7DI29 CORT PTHR10558:SF1 SOMATOSTATIN CORTISTATIN protein binding#GO:0005515;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;neuropeptide hormone activity#GO:0005184;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664 signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000046547.1|UniProtKB=F6WQN4 F6WQN4 LOC100012973 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013044.5|UniProtKB=F7G173 F7G173 CASC3 PTHR13434:SF0 PROTEIN CASC3 PROTEIN CASC3 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exon-exon junction complex#GO:0035145;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000044798.1|UniProtKB=A0A5F8GX00 A0A5F8GX00 TNNC1 PTHR23064:SF47 TROPONIN TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cytoskeletal protein binding#GO:0008092 heart process#GO:0003015;muscle system process#GO:0003012;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;nervous system process#GO:0050877;muscle contraction#GO:0006936;cardiac muscle contraction#GO:0060048;neuromuscular process#GO:0050905;circulatory system process#GO:0003013;heart contraction#GO:0060047;system process#GO:0003008 supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000021349.2|UniProtKB=H9H7Z1 H9H7Z1 METTL1 PTHR23417:SF16 3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101 tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;methyltransferase complex#GO:0034708 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000000210.3|UniProtKB=F6SZY6 F6SZY6 RPRD1B PTHR12460:SF3 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 1B enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 MONDO|Ensembl=ENSMODG00000042038.1|UniProtKB=A0A5F8GWE3 A0A5F8GWE3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016290.4|UniProtKB=F7AU35 F7AU35 ZNFX1 PTHR10887:SF341 DNA2/NAM7 HELICASE FAMILY NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular component assembly#GO:0022607;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;regulatory ncRNA-mediated heterochromatin formation#GO:0031048 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000012927.5|UniProtKB=F7GC31 F7GC31 ZNF202 PTHR23226:SF195 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 202 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000047645.1|UniProtKB=A0A5F8GAU8 A0A5F8GAU8 COL8A2 PTHR24023:SF855 COLLAGEN ALPHA COLLAGEN ALPHA-2(VIII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000043329.1|UniProtKB=A0A5F8GU72 A0A5F8GU72 SERPINF2 PTHR11461:SF20 SERINE PROTEASE INHIBITOR, SERPIN ALPHA-2-ANTIPLASMIN enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234 positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of coagulation#GO:0050820;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of coagulation#GO:0050818 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Plasminogen activating cascade#P00050>alpha2 antiplasmin#P01264;Blood coagulation#P00011>alpha2-antiplasmin#P00428 MONDO|Ensembl=ENSMODG00000005352.2|UniProtKB=F6YLK2 F6YLK2 LOC130453764 PTHR26454:SF53 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6J1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014102.3|UniProtKB=F6QIX0 F6QIX0 PTHR16103:SF0 TRANSMEMBRANE PROTEIN 140 TRANSMEMBRANE PROTEIN 140 MONDO|Ensembl=ENSMODG00000016375.4|UniProtKB=F7ER90 F7ER90 GLIS2 PTHR19818:SF84 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN GLIS2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000029275.2|UniProtKB=K7E3C8 K7E3C8 PTHR46890:SF56 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED OS06G0484800 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000005977.4|UniProtKB=F7DVQ1 F7DVQ1 SEC14L5 PTHR23324:SF39 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 5 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000007058.4|UniProtKB=F6UF61 F6UF61 CARS1 PTHR10890:SF33 CYSTEINYL-TRNA SYNTHETASE CYSTEINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000006451.4|UniProtKB=F7FH19 F7FH19 TBC1D13 PTHR22957:SF27 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 13 GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000019605.4|UniProtKB=A0A5F8GVS6 A0A5F8GVS6 KIF2A PTHR24115:SF486 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF2A microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092 microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000017628.3|UniProtKB=F6ZSG2 F6ZSG2 BLOC1S6 PTHR31328:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 6 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 6 establishment of organelle localization#GO:0051656;cellular localization#GO:0051641;localization#GO:0051179;pigmentation#GO:0043473;organelle localization#GO:0051640;cellular pigmentation#GO:0033059;establishment of vesicle localization#GO:0051650;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;intracellular transport#GO:0046907 cytoskeleton#GO:0005856;stress fiber#GO:0001725;intracellular protein-containing complex#GO:0140535;cell-cell contact zone#GO:0044291;cell junction#GO:0030054;neuromuscular junction#GO:0031594;membraneless organelle#GO:0043228;actomyosin#GO:0042641;cell-cell junction#GO:0005911;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;transport vesicle#GO:0030133;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;BLOC-1 complex#GO:0031083;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;actin filament bundle#GO:0032432;vesicle#GO:0031982;actin cytoskeleton#GO:0015629;intracellular vesicle#GO:0097708;postsynapse#GO:0098794;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000044070.1|UniProtKB=A0A5F8GYY4 A0A5F8GYY4 PIGP PTHR46346:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 transferase#PC00220 MONDO|Ensembl=ENSMODG00000016055.4|UniProtKB=F6YTR2 F6YTR2 LAMB4 PTHR10574:SF279 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-4 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;cell adhesion#GO:0007155;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular process#GO:0009987;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular component assembly#GO:0022607;plasma membrane bounded cell projection morphogenesis#GO:0120039;substrate adhesion-dependent cell spreading#GO:0034446;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell motility#GO:0048870;external encapsulating structure organization#GO:0045229;system development#GO:0048731;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;cell-substrate adhesion#GO:0031589;axon development#GO:0061564;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;tissue development#GO:0009888;extracellular matrix assembly#GO:0085029;cell migration#GO:0016477;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 MONDO|Ensembl=ENSMODG00000047131.1|UniProtKB=A0A5F8G229 A0A5F8G229 LOC100009836 PTHR20383:SF9 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;termination of RNA polymerase II transcription#GO:0006369;transcription by RNA polymerase II#GO:0006366 cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000002620.4|UniProtKB=A0A5F8GGD8 A0A5F8GGD8 KIF2C PTHR24115:SF454 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF2C microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774 plasma membrane bounded cell projection organization#GO:0120036;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000025757.2|UniProtKB=F7G3M4 F7G3M4 PTHR11430:SF124 LIPOCALIN LIPOCALIN 1-LIKE PROTEIN 1-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000040848.1|UniProtKB=A0A5F8G2I2 A0A5F8G2I2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010714.4|UniProtKB=F7G7V1 F7G7V1 DDHD2 PTHR23509:SF7 PA-PL1 PHOSPHOLIPASE FAMILY TRIACYLGLYCEROL HYDROLASE DDHD2 glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;triacylglycerol lipase activity#GO:0004806;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 metabolite interconversion enzyme#PC00262;phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000041526.1|UniProtKB=A0A5F8G4I8 A0A5F8G4I8 PTHR23262:SF180 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 12-1-RELATED structural protein#PC00211 MONDO|Ensembl=ENSMODG00000025711.2|UniProtKB=F6T346 F6T346 PTHR14759:SF37 STOP PROTEIN MAP6 DOMAIN-CONTAINING PROTEIN 1 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;regulation of microtubule-based process#GO:0032886;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cis-Golgi network#GO:0005801;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000014643.4|UniProtKB=F6YNY0 F6YNY0 RAD51C PTHR46239:SF1 DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C DNA REPAIR PROTEIN RAD51 HOMOLOG 3 DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;binding#GO:0005488;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;four-way junction DNA binding#GO:0000400;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;DNA binding#GO:0003677 protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;cellular process#GO:0009987;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;response to stimulus#GO:0050896;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA repair#GO:0006281;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;sexual reproduction#GO:0019953;reproductive process#GO:0022414;homologous recombination#GO:0035825;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;replication fork#GO:0005657 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000002147.3|UniProtKB=H9H5Z8 H9H5Z8 TP53I3 PTHR48106:SF18 QUINONE OXIDOREDUCTASE PIG3-RELATED QUINONE OXIDOREDUCTASE PIG3 catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Huntington disease#P00029>PIG3#G01535 MONDO|Ensembl=ENSMODG00000019327.4|UniProtKB=K7E1P3 K7E1P3 PTHR28333:SF2 NUCLEAR FRAGILE X MENTAL RETARDATION-INTERACTING PROTEIN 2 FMR1-INTERACTING PROTEIN NUFIP2 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000008312.4|UniProtKB=F7FGW4 F7FGW4 TBCE PTHR15140:SF31 TUBULIN-SPECIFIC CHAPERONE E TUBULIN-SPECIFIC CHAPERONE E protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000020737.4|UniProtKB=F7AN70 F7AN70 STAP1 PTHR16186:SF10 SIGNAL-TRANSDUCING ADAPTOR PROTEIN-RELATED SIGNAL-TRANSDUCING ADAPTOR PROTEIN 1 molecular adaptor activity#GO:0060090;binding#GO:0005488;kinase binding#GO:0019900;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;signaling adaptor activity#GO:0035591;protein binding#GO:0005515 regulation of B cell receptor signaling pathway#GO:0050855;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of signaling#GO:0023056;regulation of immune response#GO:0050776;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006635.3|UniProtKB=F7G4C4 F7G4C4 LOC103106423 PTHR12865:SF6 PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-BETA phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;vesicle organization#GO:0016050;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;Golgi organization#GO:0007030 Golgi apparatus#GO:0005794;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;plasma membrane#GO:0005886;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 MONDO|Ensembl=ENSMODG00000047894.1|UniProtKB=H9H891 H9H891 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000002757.3|UniProtKB=A0A5F8G4P5 A0A5F8G4P5 PADI2 PTHR10837:SF12 PEPTIDYLARGININE DEIMINASE PROTEIN-ARGININE DEIMINASE TYPE-2 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;histone modifying activity#GO:0140993 cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000006605.3|UniProtKB=F6ZWX7 F6ZWX7 NIPSNAP2 PTHR21017:SF14 NIPSNAP-RELATED PROTEIN NIPSNAP HOMOLOG 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;process utilizing autophagic mechanism#GO:0061919;mitophagy#GO:0000423;cellular process#GO:0009987;autophagy#GO:0006914;macroautophagy#GO:0016236;catabolic process#GO:0009056 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000012360.4|UniProtKB=F7E1S4 F7E1S4 SKAP1 PTHR15129:SF1 SRC-ASSOCIATED ADAPTOR PROTEIN SRC KINASE-ASSOCIATED PHOSPHOPROTEIN 1 immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;regulation of immune response#GO:0050776;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cell adhesion mediated by integrin#GO:0033628;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of cell adhesion#GO:0045785;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;regulation of leukocyte cell-cell adhesion#GO:1903037;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of cellular process#GO:0048522 cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017585.4|UniProtKB=F7B594 F7B594 NFYC PTHR10252:SF156 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 MONDO|Ensembl=ENSMODG00000003418.4|UniProtKB=A0A5F8H5H8 A0A5F8H5H8 C8A PTHR45742:SF1 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C8 ALPHA CHAIN positive regulation of immune response#GO:0050778;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;humoral immune response#GO:0006959;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;complement activation#GO:0006956;activation of immune response#GO:0002253;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of immune response#GO:0050776;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789 extracellular region#GO:0005576;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 complement component#PC00078 MONDO|Ensembl=ENSMODG00000016445.4|UniProtKB=A0A5F8GI09 A0A5F8GI09 TFAP2C PTHR10812:SF9 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2 GAMMA DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000044863.1|UniProtKB=A0A5F8HAZ8 A0A5F8HAZ8 PTHR11347:SF135 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 4C cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 hydrolase#PC00121;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000041660.1|UniProtKB=A0A5F8H6A5 A0A5F8H6A5 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020629.4|UniProtKB=F7F3Z6 F7F3Z6 ARHGEF38 PTHR22834:SF17 NUCLEAR FUSION PROTEIN FUS2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 38 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000050945.1|UniProtKB=F7BC09 F7BC09 LOC100020393 PTHR26450:SF77 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027515.2|UniProtKB=K7DZ09 K7DZ09 PTHR35269:SF1 SMALL VCP/P97-INTERACTING PROTEIN SMALL VCP_P97-INTERACTING PROTEIN negative regulation of proteasomal protein catabolic process#GO:1901799;regulation of ERAD pathway#GO:1904292;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;regulation of response to endoplasmic reticulum stress#GO:1905897;negative regulation of cellular component organization#GO:0051129;negative regulation of catabolic process#GO:0009895;regulation of establishment of protein localization#GO:0070201;negative regulation of protein-containing complex assembly#GO:0031333;regulation of protein catabolic process#GO:0042176;biological regulation#GO:0065007;negative regulation of protein transport#GO:0051224;negative regulation of response to stimulus#GO:0048585;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;negative regulation of metabolic process#GO:0009892;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of protein transport#GO:0051223;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of protein-containing complex assembly#GO:0043254;regulation of protein localization#GO:0032880;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of biological process#GO:0048518;positive regulation of autophagy#GO:0010508;regulation of protein metabolic process#GO:0051246;regulation of transport#GO:0051049;regulation of localization#GO:0032879 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 MONDO|Ensembl=ENSMODG00000007371.4|UniProtKB=F7ACX6 F7ACX6 RIC3 PTHR21723:SF3 RESISTANCE TO INHIBITORS OF CHOLINESTERASE PROTEIN 3 RIC3 PROTEIN RIC-3 localization#GO:0051179;cell communication#GO:0007154;intracellular protein localization#GO:0008104;trans-synaptic signaling#GO:0099537;synaptic transmission, cholinergic#GO:0007271;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;macromolecule localization#GO:0033036;cellular process#GO:0009987;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cell projection#GO:0042995;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000017504.4|UniProtKB=F7F183 F7F183 ALDH8A1 PTHR43720:SF4 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;cellular process#GO:0009987;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;regulation of hormone levels#GO:0010817;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 MONDO|Ensembl=ENSMODG00000020190.4|UniProtKB=F7G8I7 F7G8I7 LOC100616863 PTHR26452:SF354 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5A1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025784.3|UniProtKB=F7FSR3 F7FSR3 PTHR15172:SF1 GALACTOCEREBROSIDASE GALACTOCEREBROSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 ceramide metabolic process#GO:0006672;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;carbohydrate derivative catabolic process#GO:1901136;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;glycolipid metabolic process#GO:0006664;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149 vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;galactosidase#PC00104 MONDO|Ensembl=ENSMODG00000008937.4|UniProtKB=F7GD42 F7GD42 CAND1 PTHR12696:SF1 TIP120 CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;protein-containing complex assembly#GO:0065003;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000004681.4|UniProtKB=F6U6H6 F6U6H6 SF3A2 PTHR23205:SF0 SPLICING FACTOR 3A SUBUNIT 2 SPLICING FACTOR 3A SUBUNIT 2 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613 protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000001491.4|UniProtKB=F7F4P8 F7F4P8 MBL2 PTHR24024:SF35 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A MANNOSE-BINDING PROTEIN A signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089 regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;homeostatic process#GO:0042592;regulation of immune response#GO:0050776;positive regulation of endocytosis#GO:0045807;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;complement activation#GO:0006956;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;multicellular organismal-level homeostasis#GO:0048871;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;immune system process#GO:0002376;positive regulation of cellular component organization#GO:0051130;defense response to other organism#GO:0098542;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;defense response to symbiont#GO:0140546;positive regulation of transport#GO:0051050;regulation of localization#GO:0032879;regulation of transport#GO:0051049;humoral immune response#GO:0006959;regulation of endocytosis#GO:0030100;chemical homeostasis#GO:0048878;immune effector process#GO:0002252 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211;surfactant#PC00212 MONDO|Ensembl=ENSMODG00000010306.6|UniProtKB=F7GLB3 F7GLB3 PTHR12349:SF1 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 PALMITOYLTRANSFERASE ZDHHC8 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of transport#GO:0051049;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of transport#GO:0051050 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000015334.4|UniProtKB=F6XFG6 F6XFG6 SLC23A3 PTHR11119:SF57 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SOLUTE CARRIER FAMILY 23 MEMBER 3 transporter#PC00227 MONDO|Ensembl=ENSMODG00000006787.3|UniProtKB=F6PH60 F6PH60 GLUL PTHR20852:SF45 GLUTAMINE SYNTHETASE GLUTAMINE SYNTHETASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ligase#PC00142 Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968;Glutamine glutamate conversion#P02745>Glutamine synthase#P04483 MONDO|Ensembl=ENSMODG00000005666.3|UniProtKB=A0A5F8GWJ4 A0A5F8GWJ4 PTHR26453:SF110 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2G6 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008212.3|UniProtKB=F6ZYK3 F6ZYK3 HES5 PTHR10985:SF159 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;anterior/posterior pattern specification#GO:0009952;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 MONDO|Ensembl=ENSMODG00000010379.3|UniProtKB=F7AVQ1 F7AVQ1 LOC100028273 PTHR26452:SF977 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009183.3|UniProtKB=A0A5F8HD26 A0A5F8HD26 TMEM68 PTHR22753:SF14 TRANSMEMBRANE PROTEIN 68 DGAT1_2-INDEPENDENT ENZYME SYNTHESIZING STORAGE LIPIDS cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000013563.4|UniProtKB=F7BIH5 F7BIH5 VIPR1 PTHR45620:SF24 PDF RECEPTOR-LIKE PROTEIN-RELATED VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021118.4|UniProtKB=F6QXJ5 F6QXJ5 CFAP47 PTHR45912:SF4 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 47 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 47 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell projection organization#GO:0030030;spermatogenesis#GO:0007283;developmental process#GO:0032502;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000046681.1|UniProtKB=F7C9Y4 F7C9Y4 LOC100028081 PTHR26452:SF310 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000001788.4|UniProtKB=F6WIS8 F6WIS8 CEP250 PTHR23159:SF1 CENTROSOMAL PROTEIN 2 CENTROSOME-ASSOCIATED PROTEIN CEP250 cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000017661.4|UniProtKB=A0A5F8GQ51 A0A5F8GQ51 PTPRK PTHR19134:SF209 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE KAPPA phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;cell communication#GO:0007154;anatomical structure development#GO:0048856;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000025759.2|UniProtKB=F7G3L0 F7G3L0 PTHR11430:SF124 LIPOCALIN LIPOCALIN 1-LIKE PROTEIN 1-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000016900.4|UniProtKB=F6X169 F6X169 SHPRH PTHR45865:SF2 E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE SHPRH catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 DNA damage response#GO:0006974;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;protein modification process#GO:0036211;primary metabolic process#GO:0044238;response to stimulus#GO:0050896 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000016600.4|UniProtKB=F6ZD74 F6ZD74 PDPK1 PTHR24356:SF449 SERINE/THREONINE-PROTEIN KINASE 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166 non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>PDK1/2#P04616;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PDK1#P00831;PI3 kinase pathway#P00048>P110ACT#P01177;Ras Pathway#P04393>PDK#P04555;Interleukin signaling pathway#P00036>PDK1/2#P00985;PI3 kinase pathway#P00048>PDK1#P01196;CCKR signaling map#P06959>PDPK1#P07162;PI3 kinase pathway#P00048>PDK1 ACT#P01190;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PDK1/2#P00903;PDGF signaling pathway#P00047>PDK1/2#P01164;p53 pathway feedback loops 2#P04398>PDK1/2#P04656 MONDO|Ensembl=ENSMODG00000000334.3|UniProtKB=A0A5F8G9E1 A0A5F8G9E1 GGT5 PTHR11686:SF19 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 5 PROENZYME catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 response to stimulus#GO:0050896;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;glutathione metabolic process#GO:0006749;inflammatory response#GO:0006954;icosanoid metabolic process#GO:0006690;lipid biosynthetic process#GO:0008610;icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;response to stress#GO:0006950;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;sulfur compound catabolic process#GO:0044273;defense response#GO:0006952;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000048523.1|UniProtKB=A0A5F8HFD3 A0A5F8HFD3 LOC100025123 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000021463.2|UniProtKB=F6U8Y5 F6U8Y5 PTHR23049:SF81 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT POLYPEPTIDE 9 cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;binding#GO:0005488;protein binding#GO:0005515 striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;actomyosin structure organization#GO:0031032;cell development#GO:0048468;muscle cell development#GO:0055001;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 membraneless organelle#GO:0043228;stress fiber#GO:0001725;cytoskeleton#GO:0005856;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;myosin complex#GO:0016459;actomyosin#GO:0042641;contractile muscle fiber#GO:0043292;actin filament bundle#GO:0032432;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000015073.4|UniProtKB=A0A5F8GNU9 A0A5F8GNU9 P3H2 PTHR14049:SF1 LEPRECAN 1 PROLYL 3-HYDROXYLASE 2 dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 extracellular matrix glycoprotein#PC00100 MONDO|Ensembl=ENSMODG00000038775.1|UniProtKB=A0A5F8GDU9 A0A5F8GDU9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000018501.4|UniProtKB=F7B4H3 F7B4H3 ASB13 PTHR24136:SF53 SOWAH (DROSOPHILA) HOMOLOG ANKYRIN REPEAT AND SOCS BOX CONTAINING 13 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 MONDO|Ensembl=ENSMODG00000018828.4|UniProtKB=A0A5F8H9H7 A0A5F8H9H7 PKHD1 PTHR46769:SF1 POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1 FIBROCYSTIN MONDO|Ensembl=ENSMODG00000002949.3|UniProtKB=F6PK94 F6PK94 B4GALT2 PTHR19300:SF32 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000029325.2|UniProtKB=K7E5V4 K7E5V4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000002369.4|UniProtKB=A0A5F8GQL0 A0A5F8GQL0 ECE2 PTHR11733:SF127 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED EEF1AKMT4-ECE2 READTHROUGH TRANSCRIPT PROTEIN-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 MONDO|Ensembl=ENSMODG00000001881.4|UniProtKB=F6S5F8 F6S5F8 SOCS3 PTHR10155:SF11 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 3 cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956 MONDO|Ensembl=ENSMODG00000016532.3|UniProtKB=A0A5F8GC06 A0A5F8GC06 PTHR24020:SF18 COLLAGEN ALPHA COLLAGEN ALPHA-1(VI) CHAIN animal organ development#GO:0048513;cellular developmental process#GO:0048869;striated muscle cell differentiation#GO:0051146;muscle organ development#GO:0007517;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;tissue development#GO:0009888;skeletal muscle tissue development#GO:0007519;cellular process#GO:0009987;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;muscle tissue development#GO:0060537;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;muscle structure development#GO:0061061;cell differentiation#GO:0030154;cell development#GO:0048468;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000004126.4|UniProtKB=F6UWF7 F6UWF7 PRPH PTHR45652:SF14 GLIAL FIBRILLARY ACIDIC PROTEIN PERIPHERIN structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;cytoskeleton organization#GO:0007010 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 cytoskeletal protein#PC00085;intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000009810.4|UniProtKB=F6SG28 F6SG28 RAB11A PTHR47979:SF110 DRAB11-RELATED RAS-RELATED PROTEIN RAB-11A nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cellular localization#GO:0051641;secretion by cell#GO:0032940;protein transport#GO:0015031;regulation of biological quality#GO:0065008;protein localization to membrane#GO:0072657;endocytic recycling#GO:0032456;establishment of organelle localization#GO:0051656;export from cell#GO:0140352;protein localization to cell periphery#GO:1990778;intracellular protein transport#GO:0006886;protein localization to synapse#GO:0035418;exocytosis#GO:0006887;endosomal transport#GO:0016197;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;establishment of protein localization to membrane#GO:0090150;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;establishment of vesicle localization#GO:0051650;cellular pigmentation#GO:0033059;protein localization to cell junction#GO:1902414;organelle localization#GO:0051640;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;pigmentation#GO:0043473;localization#GO:0051179;secretion#GO:0046903;protein localization to plasma membrane#GO:0072659;intracellular transport#GO:0046907;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;vesicle localization#GO:0051648;endosome to plasma membrane protein transport#GO:0099638;biological regulation#GO:0065007 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;postsynapse#GO:0098794;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;cell junction#GO:0030054;cytoplasm#GO:0005737;endomembrane system#GO:0012505;transport vesicle#GO:0030133 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000006810.5|UniProtKB=F6PGK6 F6PGK6 TOR1A PTHR10760:SF15 TORSIN TORSIN-1A cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 nuclear envelope organization#GO:0006998;intracellular protein localization#GO:0008104;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;protein localization to nucleus#GO:0034504;cellular component organization#GO:0016043;organelle organization#GO:0006996;macromolecule localization#GO:0033036;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;protein localization to organelle#GO:0033365 organelle lumen#GO:0043233;organelle envelope#GO:0031967;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;nucleus#GO:0005634;endomembrane system#GO:0012505;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endoplasmic reticulum#GO:0005783 chaperone#PC00072 Parkinson disease#P00049>Torsin A#P01221 MONDO|Ensembl=ENSMODG00000018522.3|UniProtKB=F7AG80 F7AG80 SLC17A5 PTHR11662:SF432 SOLUTE CARRIER FAMILY 17 SIALIN carbohydrate derivative transmembrane transporter activity#GO:1901505;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;apical part of cell#GO:0045177;lytic vacuole#GO:0000323;apical plasma membrane#GO:0016324;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000003196.3|UniProtKB=F6VG26 F6VG26 EIF2B5 PTHR45887:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON TRANSLATION INITIATION FACTOR EIF2B SUBUNIT EPSILON guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;translation factor activity#GO:0180051;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;GTPase regulator activity#GO:0030695;translation initiation factor binding#GO:0031369;nucleoside-triphosphatase regulator activity#GO:0060589 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;guanyl-nucleotide exchange factor complex#GO:0032045;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000000192.4|UniProtKB=F6TFQ0 F6TFQ0 GNA12 PTHR10218:SF130 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-12 binding#GO:0005488;signaling receptor binding#GO:0005102;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;G protein-coupled receptor binding#GO:0001664;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;intracellular signal transduction#GO:0035556;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;apical plasma membrane#GO:0016324;cytoplasmic side of plasma membrane#GO:0009898;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;cell projection membrane#GO:0031253;side of membrane#GO:0098552;brush border#GO:0005903;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;brush border membrane#GO:0031526;protein-containing complex#GO:0032991;apical part of cell#GO:0045177;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897 heterotrimeric G-protein#PC00117;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000009502.2|UniProtKB=F7F9L7 F7F9L7 PHYHIP PTHR15698:SF9 PROTEIN CBG15099 PHYTANOYL-COA HYDROXYLASE-INTERACTING PROTEIN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000047878.1|UniProtKB=A0A5F8G8A2 A0A5F8G8A2 OLFM4 PTHR23192:SF7 OLFACTOMEDIN-RELATED OLFACTOMEDIN-4 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000009124.4|UniProtKB=A0A5F8GUJ4 A0A5F8GUJ4 PRMT3 PTHR11006:SF125 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 3 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;histone modifying activity#GO:0140993;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000011727.4|UniProtKB=F7FST5 F7FST5 PSMA4 PTHR11599:SF13 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-4 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;proteasome complex#GO:0000502;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 MONDO|Ensembl=ENSMODG00000012424.3|UniProtKB=F7G635 F7G635 COPZ2 PTHR11043:SF4 ZETA-COAT PROTEIN COATOMER SUBUNIT ZETA-2 intra-Golgi vesicle-mediated transport#GO:0006891;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234 organelle#GO:0043226;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;COPI-coated vesicle#GO:0030137;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle coat#GO:0030120;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000048993.1|UniProtKB=A0A5F8H185 A0A5F8H185 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000020031.3|UniProtKB=F7A6X9 F7A6X9 OR5AS1 PTHR26452:SF704 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AS1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000041366.1|UniProtKB=F6X371 F6X371 LOC100023561 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000003821.4|UniProtKB=F6YVD7 F6YVD7 AGA PTHR10188:SF50 L-ASPARAGINASE N(4)-(BETA-N-ACETYLGLUCOSAMINYL)-L-ASPARAGINASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764 protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000042156.1|UniProtKB=A0A5F8HBW6 A0A5F8HBW6 LOC100009737 PTHR26453:SF156 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002305.4|UniProtKB=F6YDT8 F6YDT8 WDFY4 PTHR46108:SF3 BLUE CHEESE WD REPEAT- AND FYVE DOMAIN-CONTAINING PROTEIN 4 immune system process#GO:0002376;antigen processing and presentation#GO:0019882 MONDO|Ensembl=ENSMODG00000048412.1|UniProtKB=A0A5F8GS47 A0A5F8GS47 LOC107650591 PTHR38503:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 1 SMALL INTEGRAL MEMBRANE PROTEIN 1 immune system process#GO:0002376;developmental process#GO:0032502;homeostasis of number of cells#GO:0048872;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;erythrocyte differentiation#GO:0030218;multicellular organismal-level homeostasis#GO:0048871;cellular process#GO:0009987;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;multicellular organismal process#GO:0032501;homeostatic process#GO:0042592;hemopoiesis#GO:0030097;cell development#GO:0048468 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000014142.3|UniProtKB=A0A5F8GF40 A0A5F8GF40 CHCT1 PTHR21765:SF1 SIMILAR TO CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1 (CHD-1) CHD1 HELICAL C-TERMINAL DOMAIN CONTAINING PROTEIN 1 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000003593.3|UniProtKB=F7FBI1 F7FBI1 PTHR23120:SF5 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT FAMILY MEMBER 9 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000038208.1|UniProtKB=A0A5F8GYA5 A0A5F8GYA5 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000008796.4|UniProtKB=A0A5F8GGQ1 A0A5F8GGQ1 MARK2 PTHR24346:SF56 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE MARK2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000016298.4|UniProtKB=F7ATG7 F7ATG7 PTGIS PTHR24306:SF4 FAMILY NOT NAMED PROSTACYCLIN SYNTHASE isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity#GO:0003824 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;unsaturated fatty acid metabolic process#GO:0033559;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;icosanoid metabolic process#GO:0006690;lipid biosynthetic process#GO:0008610;unsaturated fatty acid biosynthetic process#GO:0006636;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;icosanoid biosynthetic process#GO:0046456;oxoacid metabolic process#GO:0043436;prostaglandin metabolic process#GO:0006693;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281 MONDO|Ensembl=ENSMODG00000045992.1|UniProtKB=A0A5F8H1F8 A0A5F8H1F8 MRPL21 PTHR21349:SF0 50S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN BL21M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 Methylcitrate cycle#P02754>Aconitase#P03028 MONDO|Ensembl=ENSMODG00000025235.1|UniProtKB=F7F6C4 F7F6C4 LOC103106805 PTHR26454:SF18 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C76 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005409.4|UniProtKB=F7FVQ7 F7FVQ7 MRPS26 PTHR21035:SF2 28S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN MS26 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000042307.1|UniProtKB=A0A5F8GIS0 A0A5F8GIS0 PTHR19422:SF123 GAG RETROVIRAL POLYPROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001048.4|UniProtKB=A0A5F8GKA1 A0A5F8GKA1 UHMK1 PTHR46962:SF1 SERINE/THREONINE-PROTEIN KINASE KIST SERINE_THREONINE-PROTEIN KINASE KIST phosphotransferase activity, alcohol group as acceptor#GO:0016773;ribonucleoprotein complex binding#GO:0043021;protein kinase activity#GO:0004672;protein-containing complex binding#GO:0044877;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;regulation of translational initiation#GO:0006446;positive regulation of protein metabolic process#GO:0051247;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of translation#GO:0045727;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;neuron projection cytoplasm#GO:0120111;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;neuron projection#GO:0043005;nucleus#GO:0005634;membraneless organelle#GO:0043228 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000019039.4|UniProtKB=A0A5F8GNQ0 A0A5F8GNQ0 PCM1 PTHR14164:SF12 PERICENTRIOLAR MATERIAL 1-RELATED PERICENTRIOLAR MATERIAL 1 PROTEIN organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000009391.4|UniProtKB=K7E2U5 K7E2U5 MIEF1 PTHR16451:SF12 MITOCHONDRIAL DYNAMICS PROTEINS 49/51 FAMILY MEMBER MITOCHONDRIAL DYNAMICS PROTEIN MIEF1 regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of mitochondrial fission#GO:0090140;positive regulation of mitochondrial fission#GO:0090141;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;positive regulation of cellular component organization#GO:0051130;positive regulation of developmental process#GO:0051094;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of organelle organization#GO:0010638 outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000023436.2|UniProtKB=F7EBK0 F7EBK0 VN2R541 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000024163.2|UniProtKB=F6WXB5 F6WXB5 PTHR15527:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM6 HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM6 HOMOLOG bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000000141.4|UniProtKB=A0A5F8GKN8 A0A5F8GKN8 NDUFAF1 PTHR13194:SF18 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30, MITOCHONDRIAL NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000049152.1|UniProtKB=A0A5F8HIQ6 A0A5F8HIQ6 PTHR45713:SF20 FTP DOMAIN-CONTAINING PROTEIN PENTRAXIN PRECURSOR MONDO|Ensembl=ENSMODG00000021356.4|UniProtKB=H9H7Z7 H9H7Z7 NDC1 PTHR13269:SF6 NUCLEOPORIN NDC1 NUCLEOPORIN NDC1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 nuclear pore organization#GO:0006999;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000015971.4|UniProtKB=F7FCW8 F7FCW8 DOCK4 PTHR45653:SF7 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 4 binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 response to external stimulus#GO:0009605;cell chemotaxis#GO:0060326;chemotaxis#GO:0006935;cellular response to chemical stimulus#GO:0070887;locomotion#GO:0040011;cell motility#GO:0048870;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000006125.3|UniProtKB=A0A5F8HHZ2 A0A5F8HHZ2 KIZ PTHR16299:SF2 CENTROSOMAL PROTEIN KIZUNA CENTROSOMAL PROTEIN KIZUNA microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000009606.4|UniProtKB=A0A5F8HHV6 A0A5F8HHV6 GFRA1 PTHR10269:SF3 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;system development#GO:0048731;nervous system development#GO:0007399 external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;side of membrane#GO:0098552;membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015262.4|UniProtKB=F6U375 F6U375 LOC100010725 PTHR11127:SF2 60S RIBOSOMAL PROTEIN L14 LARGE RIBOSOMAL SUBUNIT PROTEIN EL14 structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000009483.5|UniProtKB=F6QKJ3 F6QKJ3 PES1 PTHR12221:SF6 PESCADILLO - RELATED PESCADILLO HOMOLOG RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843 cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;90S preribosome#GO:0030686;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000009393.3|UniProtKB=F7CPF3 F7CPF3 MRPL35 PTHR15909:SF0 39S RIBOSOMAL PROTEIN L35, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000014415.4|UniProtKB=A0A5F8G712 A0A5F8G712 DLAT PTHR23151:SF94 DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746 cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;pyruvate metabolic process#GO:0006090;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;acetyl-CoA metabolic process#GO:0006084;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;mitochondrion#GO:0005739;oxidoreductase complex#GO:1990204;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 transferase#PC00220;acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000020795.3|UniProtKB=F6S7P0 F6S7P0 PTHR24006:SF947 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 10 cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;signal transduction#GO:0007165;regulation of protein stability#GO:0031647;cellular process#GO:0009987;regulation of catabolic process#GO:0009894;DNA damage response#GO:0006974;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of autophagy#GO:0010506;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554 nucleus#GO:0005634;vesicle#GO:0031982;cytosol#GO:0005829;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000009441.4|UniProtKB=F7AYQ2 F7AYQ2 HUS1 PTHR12900:SF0 MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1 CHECKPOINT PROTEIN cellular response to stress#GO:0033554;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;mitotic DNA replication checkpoint signaling#GO:0033314;signaling#GO:0023052;metabolic process#GO:0008152;DNA recombination#GO:0006310;negative regulation of cell cycle#GO:0045786;DNA replication checkpoint signaling#GO:0000076;double-strand break repair#GO:0006302;response to stress#GO:0006950;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;recombinational repair#GO:0000725;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;nucleic acid metabolic process#GO:0090304;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;telomere maintenance#GO:0000723;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;mitotic G2/M transition checkpoint#GO:0044818;DNA damage checkpoint signaling#GO:0000077;nucleobase-containing compound metabolic process#GO:0006139;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle G2/M phase transition#GO:1902750;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of mitotic cell cycle phase transition#GO:1901991;sexual reproduction#GO:0019953;regulation of G2/M transition of mitotic cell cycle#GO:0010389;telomere organization#GO:0032200;primary metabolic process#GO:0044238;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;biological regulation#GO:0065007 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;site of double-strand break#GO:0035861;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;condensed chromosome#GO:0000793 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000020103.3|UniProtKB=F7ES06 F7ES06 SMTNL1 PTHR23167:SF45 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED SMOOTHELIN-LIKE PROTEIN 1 cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;cellular process#GO:0009987 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000044598.1|UniProtKB=A0A5F8H3S2 A0A5F8H3S2 GMPR PTHR43170:SF3 GMP REDUCTASE GMP REDUCTASE 1 reductase#PC00198;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000006128.4|UniProtKB=F7E1P5 F7E1P5 ELMO3 PTHR12771:SF16 ENGULFMENT AND CELL MOTILITY ENGULFMENT AND CELL MOTILITY PROTEIN 3 cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular process#GO:0009987;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;cytoskeleton organization#GO:0007010;cellular response to chemical stimulus#GO:0070887;actin filament-based process#GO:0030029;chemotaxis#GO:0006935;cell chemotaxis#GO:0060326;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;response to stimulus#GO:0050896;locomotion#GO:0040011 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000015832.5|UniProtKB=F7FDR5 F7FDR5 ASXL2 PTHR13578:SF11 ADDITIONAL SEX COMBS LIKE PROTEIN ASXL POLYCOMB GROUP PROTEIN ASXL2-RELATED signaling receptor binding#GO:0005102;binding#GO:0005488;chromatin binding#GO:0003682;protein binding#GO:0005515 regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;positive regulation of RNA metabolic process#GO:0051254;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;PcG protein complex#GO:0031519;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000006246.4|UniProtKB=A0A5F8GIX6 A0A5F8GIX6 CDC42BPA PTHR22988:SF31 MYOTONIC DYSTROPHY S/T KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE MRCK ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010 actomyosin#GO:0042641;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000011933.2|UniProtKB=F7DEM8 F7DEM8 OR56B4 PTHR26450:SF157 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56B34-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015117.4|UniProtKB=A0A5F8HFY1 A0A5F8HFY1 PEX11G PTHR20990:SF1 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11C cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;peroxisome organization#GO:0007031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000039454.1|UniProtKB=A0A5F8HI92 A0A5F8HI92 FLVCR1 PTHR10924:SF2 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED CHOLINE_ETHANOLAMINE TRANSPORTER FLVCR1 binding#GO:0005488;heme binding#GO:0020037;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;tetrapyrrole binding#GO:0046906 iron ion transport#GO:0006826;homeostasis of number of cells#GO:0048872;transition metal ion transport#GO:0000041;immune system process#GO:0002376;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular localization#GO:0051641;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;homeostatic process#GO:0042592;metal ion transport#GO:0030001;cell development#GO:0048468;cell differentiation#GO:0030154;mitochondrial transport#GO:0006839;myeloid cell differentiation#GO:0030099;developmental process#GO:0032502;transport#GO:0006810;iron coordination entity transport#GO:1901678;intracellular transport#GO:0046907;multicellular organismal-level homeostasis#GO:0048871;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;mitochondrion#GO:0005739 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000003865.4|UniProtKB=F7DTQ6 F7DTQ6 MCM8 PTHR11630:SF107 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA HELICASE MCM8 macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000004774.4|UniProtKB=F6WK84 F6WK84 PTHR28654:SF1 AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN dorsal/ventral pattern formation#GO:0009953;negative regulation of MAPK cascade#GO:0043409;negative regulation of protein metabolic process#GO:0051248;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;regionalization#GO:0003002;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;specification of symmetry#GO:0009799;negative regulation of cellular process#GO:0048523;regulation of protein modification process#GO:0031399;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of protein metabolic process#GO:0051246;negative regulation of signal transduction#GO:0009968;determination of bilateral symmetry#GO:0009855;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275;regulation of JNK cascade#GO:0046328 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000039698.1|UniProtKB=A0A5F8GT42 A0A5F8GT42 LOC100011657 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021205.5|UniProtKB=F6UH53 F6UH53 PTHR23317:SF71 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 10 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;neuron projection morphogenesis#GO:0048812;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501;synapse organization#GO:0050808;system development#GO:0048731;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;dendritic spine development#GO:0060996;dendrite morphogenesis#GO:0048813;postsynapse organization#GO:0099173;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;dendritic spine morphogenesis#GO:0060997;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;regulation of small GTPase mediated signal transduction#GO:0051056;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;dendritic spine organization#GO:0097061;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;dendrite development#GO:0016358;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;neuron projection organization#GO:0106027;cell projection organization#GO:0030030;regulation of Rho protein signal transduction#GO:0035023;cell morphogenesis#GO:0000902 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000002205.2|UniProtKB=F7G3P1 F7G3P1 TAF13 PTHR11380:SF17 TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 13 gene expression#GO:0010467;DNA-templated transcription#GO:0006351;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;nucleic acid biosynthetic process#GO:0141187 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000008285.4|UniProtKB=F6YIH0 F6YIH0 BTBD16 PTHR46843:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 16 BTB_POZ DOMAIN-CONTAINING PROTEIN 16 MONDO|Ensembl=ENSMODG00000002423.4|UniProtKB=A0A5F8GWY4 A0A5F8GWY4 GALK2 PTHR10457:SF7 MEVALONATE KINASE/GALACTOKINASE GALACTOKINASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065 Fructose galactose metabolism#P02744>Galactokinase#P02960 MONDO|Ensembl=ENSMODG00000009122.2|UniProtKB=F7EYI6 F7EYI6 LOC100019401 PTHR26450:SF87 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51F2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002190.3|UniProtKB=F7GE48 F7GE48 EIF4A3 PTHR47958:SF26 ATP-DEPENDENT RNA HELICASE DBP3 EUKARYOTIC INITIATION FACTOR 4A-III helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;catalytic step 2 spliceosome#GO:0071013;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000002715.3|UniProtKB=F7CED8 F7CED8 PTHR43220:SF21 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 41A MONDO|Ensembl=ENSMODG00000010902.3|UniProtKB=F7FIV7 F7FIV7 SFR1 PTHR28643:SF1 SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;recombinational repair#GO:0000725;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;DNA repair#GO:0006281;DNA damage response#GO:0006974;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular response to stress#GO:0033554;positive regulation of macromolecule metabolic process#GO:0010604;response to stress#GO:0006950;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000043606.1|UniProtKB=F6ZPX9 F6ZPX9 LOC100014414 PTHR48018:SF157 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000047236.1|UniProtKB=A0A5F8HF05 A0A5F8HF05 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000002315.4|UniProtKB=F6YDB8 F6YDB8 LRRC18 PTHR45752:SF146 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 18 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000039685.1|UniProtKB=A0A5F8GKA0 A0A5F8GKA0 PTS PTHR12589:SF10 PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE 6-PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;biosynthetic process#GO:0009058;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000008519.4|UniProtKB=A0A5F8GSF3 A0A5F8GSF3 RTN3 PTHR45799:SF4 RETICULON-LIKE PROTEIN RETICULON-3 cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;organelle organization#GO:0006996;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;endoplasmic reticulum tubular network organization#GO:0071786;endoplasmic reticulum membrane organization#GO:0090158;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 MONDO|Ensembl=ENSMODG00000009465.4|UniProtKB=F7FZD1 F7FZD1 SEC14L4 PTHR23324:SF42 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 4 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000005557.2|UniProtKB=A0A5F8GH35 A0A5F8GH35 PTHR48033:SF2 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D-LIKE RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000000403.4|UniProtKB=F6QMP7 F6QMP7 CSRP1 PTHR24215:SF23 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 1 cytoskeletal protein binding#GO:0008092;binding#GO:0005488;structural molecule activity#GO:0005198;protein binding#GO:0005515 striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;actomyosin structure organization#GO:0031032;cell development#GO:0048468;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;cellular developmental process#GO:0048869;developmental process#GO:0032502;tissue development#GO:0009888 intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;I band#GO:0031674;sarcomere#GO:0030017;membraneless organelle#GO:0043228;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000023549.2|UniProtKB=F7B9X0 F7B9X0 RPLP0 PTHR45699:SF3 60S ACIDIC RIBOSOMAL PROTEIN P0 LARGE RIBOSOMAL SUBUNIT PROTEIN UL10 structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000042989.1|UniProtKB=A0A5F8GLC9 A0A5F8GLC9 PTHR19303:SF83 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 1-LIKE DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000017718.4|UniProtKB=A0A5F8H389 A0A5F8H389 C2CD5 PTHR37412:SF2 C2 DOMAIN-CONTAINING PROTEIN 5 C2 DOMAIN-CONTAINING PROTEIN 5 phospholipid binding#GO:0005543;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169;lipid binding#GO:0008289 positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;positive regulation of vesicle fusion#GO:0031340;regulation of localization#GO:0032879;regulation of transport#GO:0051049;intracellular protein transmembrane transport#GO:0065002;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;protein localization to cell periphery#GO:1990778;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;protein localization to membrane#GO:0072657;regulation of protein localization#GO:0032880;protein transport#GO:0015031;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;transmembrane transport#GO:0055085;positive regulation of cellular component organization#GO:0051130;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;regulation of cellular process#GO:0050794;protein localization to plasma membrane#GO:0072659;regulation of transmembrane transport#GO:0034762;regulation of establishment of protein localization#GO:0070201;localization#GO:0051179;localization within membrane#GO:0051668 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000008772.4|UniProtKB=F7C727 F7C727 DYNC1I2 PTHR12442:SF37 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 2 binding#GO:0005488;protein binding#GO:0005515 transport along microtubule#GO:0010970;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810;microtubule-based transport#GO:0099111;microtubule-based movement#GO:0007018;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;dynein complex#GO:0030286;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000038134.1|UniProtKB=A0A5F8HIY6 A0A5F8HIY6 MICAL2 PTHR23167:SF39 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED [F-ACTIN]-MONOOXYGENASE MICAL2 protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497 actin cytoskeleton organization#GO:0030036;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament depolymerization#GO:0030042;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;protein-containing complex organization#GO:0043933;actin filament-based process#GO:0030029 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000050478.1|UniProtKB=A0A5F8GTI7 A0A5F8GTI7 PTHR22839:SF0 THO COMPLEX SUBUNIT 3 THO3 THO COMPLEX SUBUNIT 3 nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;transcription export complex#GO:0000346;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000029612.2|UniProtKB=K7E1L6 K7E1L6 IQCN PTHR22590:SF2 MYOSIN MOTOR DOMAIN-CONTAINING PROTEIN IQ DOMAIN-CONTAINING PROTEIN N MONDO|Ensembl=ENSMODG00000024792.2|UniProtKB=F7G064 F7G064 TMEM81 PTHR35670:SF1 TRANSMEMBRANE PROTEIN 81 TRANSMEMBRANE PROTEIN 81 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 single fertilization#GO:0007338;cellular process#GO:0009987;reproductive process#GO:0022414;fertilization#GO:0009566;sperm-egg recognition#GO:0035036;cell recognition#GO:0008037;sexual reproduction#GO:0019953;cell-cell recognition#GO:0009988 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000000152.4|UniProtKB=F6XSZ6 F6XSZ6 PTHR46754:SF1 MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000001588.4|UniProtKB=F7BBI9 F7BBI9 PRR14 PTHR14522:SF2 EMO2-RELATED PROLINE-RICH PROTEIN 14 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 MONDO|Ensembl=ENSMODG00000042969.1|UniProtKB=A0A5F8GDK9 A0A5F8GDK9 PTHR19970:SF0 RIBOSOMAL PROTEIN L39E LARGE RIBOSOMAL SUBUNIT PROTEIN EL39 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000010745.3|UniProtKB=F7FWV1 F7FWV1 MIIP PTHR34831:SF1 MIGRATION AND INVASION-INHIBITORY PROTEIN MIGRATION AND INVASION-INHIBITORY PROTEIN MONDO|Ensembl=ENSMODG00000002988.3|UniProtKB=F6Q4H1 F6Q4H1 ACTL10 PTHR11937:SF183 ACTIN ACTIN-LIKE PROTEIN 10 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000001155.3|UniProtKB=F7D404 F7D404 LOC100016081 PTHR22574:SF2 FAMILY NOT NAMED GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 3 MONDO|Ensembl=ENSMODG00000017481.3|UniProtKB=F7FEZ1 F7FEZ1 EIF3I PTHR19877:SF1 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I translation initiation factor activity#GO:0003743;RNA binding#GO:0003723;translation factor activity#GO:0180051;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;eukaryotic translation initiation factor 3 complex#GO:0005852 translation factor#PC00223;translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000003526.4|UniProtKB=F7GBT8 F7GBT8 KIF5C PTHR24115:SF380 KINESIN-RELATED KINESIN HEAVY CHAIN ISOFORM 5C isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;plus-end-directed microtubule motor activity#GO:0008574;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;synaptic vesicle localization#GO:0097479;nervous system development#GO:0007399;organelle transport along microtubule#GO:0072384;cell morphogenesis involved in neuron differentiation#GO:0048667;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;neuron projection development#GO:0031175;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;microtubule-based transport#GO:0099111;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;establishment of organelle localization#GO:0051656;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;anatomical structure morphogenesis#GO:0009653;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;mitochondrion localization#GO:0051646;neuron projection guidance#GO:0097485;vesicle cytoskeletal trafficking#GO:0099518;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411;axo-dendritic transport#GO:0008088;vesicle localization#GO:0051648;anatomical structure development#GO:0048856;localization#GO:0051179;anterograde axonal transport#GO:0008089;system development#GO:0048731;organelle localization#GO:0051640;axonal transport#GO:0098930;microtubule-based movement#GO:0007018 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000010826.3|UniProtKB=F7BE70 F7BE70 PTHR23407:SF6 ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE ATPASE INHIBITOR, MITOCHONDRIAL molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;ligase activity#GO:0016874;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;ligase activity, forming carbon-nitrogen bonds#GO:0016879;binding#GO:0005488;enzyme binding#GO:0019899 pigment metabolic process#GO:0042440;cellular process#GO:0009987;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;metabolic process#GO:0008152;developmental process#GO:0032502;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871;modified amino acid metabolic process#GO:0006575;heme biosynthetic process#GO:0006783;cell differentiation#GO:0030154;tetrapyrrole biosynthetic process#GO:0033014;small molecule metabolic process#GO:0044281;folic acid-containing compound metabolic process#GO:0006760;myeloid cell differentiation#GO:0030099;pteridine-containing compound metabolic process#GO:0042558;homeostatic process#GO:0042592;cell development#GO:0048468;tetrapyrrole metabolic process#GO:0033013;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;tetrahydrofolate biosynthetic process#GO:0046654;porphyrin-containing compound biosynthetic process#GO:0006779;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;tetrahydrofolate metabolic process#GO:0046653 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 ligase#PC00142 MONDO|Ensembl=ENSMODG00000020531.2|UniProtKB=A0A5F8GMU3 A0A5F8GMU3 TLR10 PTHR24365:SF23 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 10 signaling receptor activity#GO:0038023;lipid binding#GO:0008289;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;cell communication#GO:0007154;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to biotic stimulus#GO:0002831;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune system process#GO:0002376;toll-like receptor signaling pathway#GO:0002224;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;regulation of response to external stimulus#GO:0032101 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR#P01346 MONDO|Ensembl=ENSMODG00000009362.3|UniProtKB=F7G012 F7G012 GPR155 PTHR22829:SF5 DEP DOMAIN PROTEIN LYSOSOMAL CHOLESTEROL SIGNALING PROTEIN regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of BMP signaling pathway#GO:0030514;regulation of BMP signaling pathway#GO:0030510;negative regulation of signal transduction#GO:0009968;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000001201.3|UniProtKB=F7GH77 F7GH77 NXPH2 PTHR17103:SF11 NEUREXOPHILIN NEUREXOPHILIN-2 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;GABA-ergic synapse#GO:0098982 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000005091.2|UniProtKB=F7A3Q5 F7A3Q5 SMPD3 PTHR16320:SF8 SPHINGOMYELINASE FAMILY MEMBER SPHINGOMYELIN PHOSPHODIESTERASE 3 phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;lipase activity#GO:0016298;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 phospholipid metabolic process#GO:0006644;sphingomyelin metabolic process#GO:0006684;cellular process#GO:0009987;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000027460.2|UniProtKB=K7E0Y4 K7E0Y4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009873.3|UniProtKB=F6VUJ1 F6VUJ1 PSMC5 PTHR23073:SF12 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 8 macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;proteasome complex#GO:0000502;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000013135.2|UniProtKB=F7B030 F7B030 KCNK16 PTHR11003:SF104 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 16 monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000039526.1|UniProtKB=A0A5F8GVC0 A0A5F8GVC0 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000040709.1|UniProtKB=A0A5F8GZV8 A0A5F8GZV8 LOC100014741 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000048157.1|UniProtKB=A0A5F8GS30 A0A5F8GS30 PTHR12930:SF0 ZINC FINGER PROTEIN 183 RING FINGER PROTEIN 113A1 aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000023258.2|UniProtKB=F7B0S5 F7B0S5 PGM2 PTHR45745:SF3 PHOSPHOMANNOMUTASE 45A PHOSPHOPENTOMUTASE isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;intramolecular phosphotransferase activity#GO:0016868 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;small molecule biosynthetic process#GO:0044283;purine nucleoside metabolic process#GO:0042278;nucleobase-containing compound biosynthetic process#GO:0034654;purine-containing compound biosynthetic process#GO:0072522;metabolic process#GO:0008152 mutase#PC00160;isomerase#PC00135;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000016471.4|UniProtKB=F6ZE46 F6ZE46 PRKG1 PTHR24353:SF68 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Endothelin signaling pathway#P00019>PKG#P00567;CCKR signaling map#P06959>cGK 1#P07149 MONDO|Ensembl=ENSMODG00000013164.4|UniProtKB=F6ZM87 F6ZM87 ECH1 PTHR43149:SF7 ENOYL-COA HYDRATASE DELTA(3,5)-DELTA(2,4)-DIENOYL-COA ISOMERASE, MITOCHONDRIAL catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydratase#PC00120 MONDO|Ensembl=ENSMODG00000020612.4|UniProtKB=F6ZB66 F6ZB66 DKK2 PTHR12113:SF12 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 2 protein binding#GO:0005515;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;signaling receptor inhibitor activity#GO:0030547;signaling receptor regulator activity#GO:0030545;binding#GO:0005488 regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000015586.4|UniProtKB=F6ZV41 F6ZV41 RBKS PTHR10584:SF166 SUGAR KINASE RIBOKINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 carbohydrate kinase#PC00065;kinase#PC00137 MONDO|Ensembl=ENSMODG00000023278.1|UniProtKB=F6SEP6 F6SEP6 CLDN20 PTHR12002:SF17 CLAUDIN CLAUDIN-20 cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular process#GO:0009987;cell junction organization#GO:0034330;cellular component assembly#GO:0022607 anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;apical junction complex#GO:0043296;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 cell junction protein#PC00070;tight junction#PC00214 MONDO|Ensembl=ENSMODG00000007729.3|UniProtKB=F7EUD6 F7EUD6 STOML2 PTHR43327:SF10 STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL transporter#PC00227 MONDO|Ensembl=ENSMODG00000010491.4|UniProtKB=F7ES70 F7ES70 SHARPIN PTHR22770:SF45 UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED RANBP-TYPE AND C3HC4-TYPE ZINC FINGER-CONTAINING PROTEIN 1-RELATED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;regulation of intracellular signal transduction#GO:1902531;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of signaling#GO:0023056;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of biological process#GO:0050789 catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000014978.4|UniProtKB=F7CGF1 F7CGF1 NEK10 PTHR43671:SF92 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK10 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of cell cycle phase transition#GO:1901987 catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein kinase complex#GO:1902911;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000042938.1|UniProtKB=A0A5F8GQR9 A0A5F8GQR9 PTHR10500:SF7 BETA-MICROSEMINOPROTEIN MICROSEMINOPROTEIN BETA intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000020783.3|UniProtKB=F6YKH9 F6YKH9 PRKG2 PTHR24353:SF24 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Endothelin signaling pathway#P00019>PKG#P00567 MONDO|Ensembl=ENSMODG00000021448.4|UniProtKB=A0A5F8GLE3 A0A5F8GLE3 NDUFV2 PTHR10371:SF3 NADH DEHYDROGENASE UBIQUINONE FLAVOPROTEIN 2, MITOCHONDRIAL NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 2, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;NADH dehydrogenase activity#GO:0003954 energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775 respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 dehydrogenase#PC00092;oxidoreductase#PC00176 Parkinson disease#P00049>Complex I#P01237 MONDO|Ensembl=ENSMODG00000023842.2|UniProtKB=F6U8F9 F6U8F9 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009133.4|UniProtKB=A0A5F8G7Z4 A0A5F8G7Z4 UACA PTHR24173:SF23 ANKYRIN REPEAT CONTAINING UVEAL AUTOANTIGEN WITH COILED-COIL DOMAINS AND ANKYRIN REPEATS intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;regulation of cell communication#GO:0010646;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;apoptotic signaling pathway#GO:0097190;regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of cell communication#GO:0010648;intrinsic apoptotic signaling pathway#GO:0097193;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;signaling#GO:0023052;response to stimulus#GO:0050896;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;negative regulation of biological process#GO:0048519;negative regulation of signal transduction#GO:0009968;negative regulation of response to external stimulus#GO:0032102;regulation of response to external stimulus#GO:0032101;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000050333.1|UniProtKB=A0A5F8G1Z3 A0A5F8G1Z3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000038443.1|UniProtKB=F7C8D2 F7C8D2 PTHR11426:SF242 HISTONE H3 HISTONE H3.1 protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;organelle fission#GO:0048285;kinetochore organization#GO:0051383;localization#GO:0051179;kinetochore assembly#GO:0051382;nuclear division#GO:0000280;organelle localization#GO:0051640;organelle assembly#GO:0070925;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 MONDO|Ensembl=ENSMODG00000018230.3|UniProtKB=F6PGC2 F6PGC2 HGD PTHR11056:SF0 HOMOGENTISATE 1,2-DIOXYGENASE HOMOGENTISATE 1,2-DIOXYGENASE dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000010392.4|UniProtKB=F7AUR1 F7AUR1 NEUROD1 PTHR19290:SF88 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000003761.4|UniProtKB=F7AAQ4 F7AAQ4 PTHR10583:SF4 CHROMOGRANIN SECRETOGRANIN-1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000006660.5|UniProtKB=F7FTM4 F7FTM4 ARHGEF40 PTHR45845:SF5 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 40 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000046661.1|UniProtKB=K7E2W1 K7E2W1 PTHR24100:SF149 BUTYROPHILIN BG ANTIGEN 1, MHCB REGION-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000013445.4|UniProtKB=F7G9L3 F7G9L3 SLC12A3 PTHR11827:SF9 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 3 symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081 monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;monoatomic anion transport#GO:0006820;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;chloride transport#GO:0006821;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000007252.4|UniProtKB=F6VWU6 F6VWU6 C5AR2 PTHR24225:SF1 CHEMOTACTIC RECEPTOR C5A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR 2 G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429 basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000020713.4|UniProtKB=A0A5F8HKY3 A0A5F8HKY3 LOC100015889 PTHR43880:SF1 ALCOHOL DEHYDROGENASE ALL-TRANS-RETINOL DEHYDROGENASE [NAD(+)] ADH1B oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;zinc ion binding#GO:0008270;catalytic activity#GO:0003824;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;ion binding#GO:0043167;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;metal ion binding#GO:0046872;cation binding#GO:0043169;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745 alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;response to chemical#GO:0042221;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;regulation of biological quality#GO:0065008;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;olefinic compound metabolic process#GO:0120254;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;regulation of hormone levels#GO:0010817;carboxylic acid metabolic process#GO:0019752;cellular detoxification of aldehyde#GO:0110095;monocarboxylic acid metabolic process#GO:0032787;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;aldehyde catabolic process#GO:0046185;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;retinol metabolic process#GO:0042572;response to toxic substance#GO:0009636;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000041912.1|UniProtKB=F6ZFB2 F6ZFB2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012977.3|UniProtKB=F7CST4 F7CST4 CACFD1 PTHR13314:SF2 CALCIUM CHANNEL FLOWER HOMOLOG CALCIUM CHANNEL FLOWER HOMOLOG monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular localization#GO:0051641;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;synaptic vesicle endocytosis#GO:0048488;metal ion transport#GO:0030001;endocytosis#GO:0006897;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;calcium ion transport#GO:0006816;import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192 exocytic vesicle#GO:0070382;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;plasma membrane#GO:0005886;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle#GO:0030133 MONDO|Ensembl=ENSMODG00000045707.1|UniProtKB=A0A5F8GGC7 A0A5F8GGC7 LOC100616929 PTHR23226:SF353 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014228.4|UniProtKB=F6T9F8 F6T9F8 PTHR46540:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 12 TETRATRICOPEPTIDE REPEAT PROTEIN 12 male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;axonemal dynein complex assembly#GO:0070286;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003;sperm motility#GO:0097722;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000016890.4|UniProtKB=A0A5F8HAU6 A0A5F8HAU6 CHTF18 PTHR23389:SF33 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 CHROMOSOME TRANSMISSION FIDELITY PROTEIN 18 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000013686.4|UniProtKB=F6QPR3 F6QPR3 MKRN1 PTHR11224:SF37 MAKORIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE MAKORIN-1 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000013536.4|UniProtKB=F7CLZ9 F7CLZ9 HSD17B4 PTHR13078:SF56 PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;microbody#GO:0042579 MONDO|Ensembl=ENSMODG00000014949.4|UniProtKB=F7FI85 F7FI85 PTHR19282:SF168 TETRASPANIN TETRASPANIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000025636.3|UniProtKB=F6XW95 F6XW95 PTHR10125:SF13 P2X PURINOCEPTOR P2X PURINOCEPTOR 7 ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;signal transduction#GO:0007165;cellular process#GO:0009987;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000012286.4|UniProtKB=F7GF59 F7GF59 TDRD12 PTHR22655:SF2 ATP-DEPENDENT RNA HELICASE TDRD12-RELATED ATP-DEPENDENT RNA HELICASE TDRD12-RELATED nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;piRNA processing#GO:0034587;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000013803.1|UniProtKB=F6SYA2 F6SYA2 PTHR10078:SF27 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-1 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125 cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to oxygen-containing compound#GO:1901700;response to peptide#GO:1901652;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to molecule of bacterial origin#GO:0002237;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;defense response#GO:0006952;immune response#GO:0006955;biological regulation#GO:0065007;response to other organism#GO:0051707;response to bacterium#GO:0009617;cytokine-mediated signaling pathway#GO:0019221;inflammatory response#GO:0006954;cell communication#GO:0007154;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083;interleukin superfamily#PC00128;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000041564.1|UniProtKB=K7DZV1 K7DZV1 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000015525.4|UniProtKB=F6VI58 F6VI58 LOC100014841 PTHR24147:SF53 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN 26 MONDO|Ensembl=ENSMODG00000025247.3|UniProtKB=F7F5Y8 F7F5Y8 SEMA7A PTHR11036:SF80 SEMAPHORIN SEMAPHORIN-7A signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cell adhesion molecule binding#GO:0050839;integrin binding#GO:0005178;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677 neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;taxis#GO:0042330;response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;positive regulation of cell motility#GO:2000147;integrin-mediated signaling pathway#GO:0007229;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;regulation of response to stress#GO:0080134;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;neurogenesis#GO:0022008;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;locomotion#GO:0040011;chemotaxis#GO:0006935;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000003551.3|UniProtKB=F7GBJ1 F7GBJ1 SLC16A3 PTHR11360:SF27 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 4 monocarboxylic acid transmembrane transporter activity#GO:0008028;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178 transporter#PC00227 MONDO|Ensembl=ENSMODG00000002336.5|UniProtKB=F7BYY3 F7BYY3 DDX24 PTHR24031:SF91 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX24 maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000013660.4|UniProtKB=F6TXY8 F6TXY8 INF2 PTHR46345:SF8 INVERTED FORMIN-2 INVERTED FORMIN-2 MONDO|Ensembl=ENSMODG00000020850.3|UniProtKB=F6R0S8 F6R0S8 TRAPPC6A PTHR12817:SF2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6A cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;Golgi apparatus subcompartment#GO:0098791;intracellular protein-containing complex#GO:0140535;cis-Golgi network#GO:0005801;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794 MONDO|Ensembl=ENSMODG00000010184.4|UniProtKB=F6SUI5 F6SUI5 CLXN PTHR23055:SF75 CALCIUM BINDING PROTEINS CALAXIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000004800.4|UniProtKB=F6V6D4 F6V6D4 SYCP1 PTHR46918:SF1 SYNAPTONEMAL COMPLEX PROTEIN 1 SYNAPTONEMAL COMPLEX PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677 response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;synaptonemal complex assembly#GO:0007130;cellular component assembly#GO:0022607;homologous chromosome pairing at meiosis#GO:0007129;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;chromosome segregation#GO:0007059;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;meiosis I#GO:0007127;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;response to stimulus#GO:0050896;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;DNA damage response#GO:0006974;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;reproductive process#GO:0022414;homologous recombination#GO:0035825;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;central element#GO:0000801;synaptonemal structure#GO:0099086;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;condensed chromosome#GO:0000793 MONDO|Ensembl=ENSMODG00000015571.4|UniProtKB=F7AIQ8 F7AIQ8 MREG PTHR34340:SF3 MELANOREGULIN MELANOREGULIN cellular developmental process#GO:0048869;establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;establishment of vesicle localization#GO:0051650;cellular pigmentation#GO:0033059;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;developmental pigmentation#GO:0048066;melanocyte differentiation#GO:0030318;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;pigmentation#GO:0043473;organelle localization#GO:0051640;cell differentiation#GO:0030154;establishment of organelle localization#GO:0051656 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;melanosome#GO:0042470;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000017919.3|UniProtKB=A0A5F8H2N5 A0A5F8H2N5 RPF2 PTHR12728:SF0 BRIX DOMAIN CONTAINING PROTEIN RIBOSOME PRODUCTION FACTOR 2 HOMOLOG binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 MONDO|Ensembl=ENSMODG00000046397.1|UniProtKB=A0A5F8GAB3 A0A5F8GAB3 PTHR23292:SF46 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR HOMOLOG ion binding#GO:0043167;zinc ion binding#GO:0008270;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 vesicle#GO:0031982;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;side of membrane#GO:0098552;lysosomal membrane#GO:0005765;nucleus#GO:0005634;vesicle membrane#GO:0012506;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;cytoplasmic side of membrane#GO:0098562;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000002031.6|UniProtKB=A0A5F8HBL9 A0A5F8HBL9 TRPM6 PTHR13800:SF15 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 6 metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;kinase activity#GO:0016301;transporter activity#GO:0005215;transferase activity#GO:0016740;monoatomic cation transmembrane transporter activity#GO:0008324;protein kinase activity#GO:0004672;calcium ion transmembrane transporter activity#GO:0015085;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;monoatomic cation channel activity#GO:0005261;transferase activity, transferring phosphorus-containing groups#GO:0016772;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 transport#GO:0006810;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000037532.1|UniProtKB=A0A5F8H1G2 A0A5F8H1G2 PTHR19446:SF479 REVERSE TRANSCRIPTASES RNA-DIRECTED DNA POLYMERASE viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000018624.3|UniProtKB=F7B312 F7B312 SPSB4 PTHR12245:SF3 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 4 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;cytosol#GO:0005829;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000038956.1|UniProtKB=F7F226 F7F226 LOC100617528 PTHR24242:SF264 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 10X1 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000007804.4|UniProtKB=A0A5F8GUZ6 A0A5F8GUZ6 TMEM41B PTHR43220:SF18 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 41B autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;catabolic process#GO:0009056;organelle assembly#GO:0070925;metabolic process#GO:0008152;process utilizing autophagic mechanism#GO:0061919;autophagosome assembly#GO:0000045;vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000018163.3|UniProtKB=F7CCY5 F7CCY5 LPCAT3 PTHR13906:SF14 PORCUPINE LYSOPHOSPHOLIPID ACYLTRANSFERASE 5 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 lipid modification#GO:0030258;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;phosphatidylcholine biosynthetic process#GO:0006656;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;phosphatidylcholine metabolic process#GO:0046470;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cellular anatomical structure#GO:0110165;membrane#GO:0016020 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000008304.4|UniProtKB=F7FGZ5 F7FGZ5 MMEL1 PTHR11733:SF141 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED MEMBRANE METALLO-ENDOPEPTIDASE-LIKE 1 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000029013.2|UniProtKB=K7E3N5 K7E3N5 PTHR46123:SF4 MIX-TYPE HOMEOBOX GENE 1-RELATED MIX-TYPE HOMEOBOX GENE 1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000009857.4|UniProtKB=F7A4E9 F7A4E9 SMARCD2 PTHR13844:SF2 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000008367.4|UniProtKB=F7CDZ8 F7CDZ8 EXOC2 PTHR13043:SF1 EXOCYST COMPLEX COMPONENT SEC5 EXOCYST COMPLEX COMPONENT 2 exocytosis#GO:0006887;secretion by cell#GO:0032940;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;transport#GO:0006810;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622 Ras Pathway#P04393>Sec5#P04545 MONDO|Ensembl=ENSMODG00000046533.1|UniProtKB=A0A5F8G4S7 A0A5F8G4S7 PTHR41694:SF3 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 10 POL PROTEIN-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000049637.1|UniProtKB=A0A5F8GUQ8 A0A5F8GUQ8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007661.4|UniProtKB=F6SWR7 F6SWR7 TMEM181 PTHR31918:SF2 TRANSMEMBRANE PROTEIN 181 TRANSMEMBRANE PROTEIN 181 positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of protein secretion#GO:0050714;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;regulation of protein secretion#GO:0050708;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051;regulation of secretion#GO:0051046;positive regulation of signaling#GO:0023056;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201;regulation of secretion by cell#GO:1903530 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000039283.1|UniProtKB=A0A5F8HCL9 A0A5F8HCL9 FAM210A PTHR21377:SF1 PROTEIN FAM210B, MITOCHONDRIAL MITOCHONDRIAL INNER MEMBRANE SCAFFOLD 1 mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000044115.1|UniProtKB=A0A5F8HB22 A0A5F8HB22 PTHR23320:SF128 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 4A-LIKE transporter#PC00227 MONDO|Ensembl=ENSMODG00000000724.3|UniProtKB=F6W6H5 F6W6H5 TST PTHR11364:SF6 THIOSULFATE SULFERTANSFERASE THIOSULFATE SULFURTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;tRNA thio-modification#GO:0034227;macromolecule modification#GO:0043412;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble position uridine thiolation#GO:0002143;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transferase#PC00220 MONDO|Ensembl=ENSMODG00000019734.4|UniProtKB=F6X3Y3 F6X3Y3 CRB2 PTHR24049:SF19 CRUMBS FAMILY MEMBER PROTEIN CRUMBS HOMOLOG 2 cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell-cell adhesion#GO:0098609;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;cell adhesion#GO:0007155;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000007135.4|UniProtKB=F6RZA8 F6RZA8 NARF PTHR11615:SF124 NITRATE, FORMATE, IRON DEHYDROGENASE NUCLEAR PRELAMIN A RECOGNITION FACTOR protein binding#GO:0005515;binding#GO:0005488 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226 intracellular organelle#GO:0043229;nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856;intermediate filament#GO:0005882;intracellular protein-containing complex#GO:0140535;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear envelope#GO:0005635;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000003229.5|UniProtKB=F6TYA8 F6TYA8 DVL3 PTHR10878:SF6 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-3 binding#GO:0005488;signaling receptor binding#GO:0005102;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Alzheimer disease-presenilin pathway#P00004>Dsh#P00132;Angiogenesis#P00005>Dsh#P00200;Wnt signaling pathway#P00057>Dishevelled#P01447 MONDO|Ensembl=ENSMODG00000048117.1|UniProtKB=A0A5F8GIX7 A0A5F8GIX7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000015277.4|UniProtKB=F6TLV9 F6TLV9 ABHD16A PTHR12277:SF54 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN PHOSPHATIDYLSERINE LIPASE ABHD16A glycerophospholipase activity#GO:0004620;lipase activity#GO:0016298;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;hydrolase activity#GO:0016787 cellular process#GO:0009987;lipid catabolic process#GO:0016042;organophosphate metabolic process#GO:0019637;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;acylglycerol catabolic process#GO:0046464;glycerophospholipid catabolic process#GO:0046475;neutral lipid metabolic process#GO:0006638;phosphorus metabolic process#GO:0006793;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;glycerolipid catabolic process#GO:0046503;organophosphate catabolic process#GO:0046434 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000010576.3|UniProtKB=F6YQL0 F6YQL0 LOC100021803 PTHR24232:SF97 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013416.4|UniProtKB=A0A5F8G899 A0A5F8G899 PHLDB1 PTHR12156:SF23 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY B MEMBER 1 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;basal part of cell#GO:0045178;cell periphery#GO:0071944;cell cortex#GO:0005938 MONDO|Ensembl=ENSMODG00000013192.5|UniProtKB=F7FAB5 F7FAB5 IRX3 PTHR11211:SF14 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-3 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;cell development#GO:0048468;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000003663.3|UniProtKB=F7ACE7 F7ACE7 RPL13 PTHR11722:SF0 60S RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN EL13 structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000000376.3|UniProtKB=F6R8V4 F6R8V4 MTA3 PTHR10865:SF6 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS-ASSOCIATED PROTEIN MTA3 transcription coactivator activity#GO:0003713;histone deacetylase binding#GO:0042826;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;protein binding#GO:0005515;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000003080.4|UniProtKB=F7F5B8 F7F5B8 KDM4A PTHR10694:SF119 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4A dioxygenase activity#GO:0051213;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;protein demethylase activity#GO:0140457;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000011221.4|UniProtKB=F6S7X0 F6S7X0 GLT8D1 PTHR13778:SF3 GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000004383.4|UniProtKB=A0A5F8GM41 A0A5F8GM41 CACYBP PTHR13164:SF3 CALICYLIN BINDING PROTEIN CALCYCLIN-BINDING PROTEIN ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488 multicellular organismal process#GO:0032501;heart development#GO:0007507;circulatory system development#GO:0072359;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000045380.1|UniProtKB=F7BC24 F7BC24 LOC100020500 PTHR26450:SF77 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000042514.1|UniProtKB=A0A5F8HGN3 A0A5F8HGN3 PTHR14181:SF1 DUFFY ANTIGEN/CHEMOKINE RECEPTOR ATYPICAL CHEMOKINE RECEPTOR 1 cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023 inflammatory response#GO:0006954;response to stress#GO:0006950;defense response#GO:0006952;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011984.4|UniProtKB=F7B9I4 F7B9I4 HEMK1 PTHR18895:SF74 HEMK METHYLTRANSFERASE MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170 metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;translational termination#GO:0006415;translation#GO:0006412;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein biosynthetic process#GO:0160307;protein-containing complex disassembly#GO:0032984 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000047743.1|UniProtKB=A0A5F8G8C5 A0A5F8G8C5 monDomV1R1219 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000097.5|UniProtKB=F6YCA2 F6YCA2 CCDC82 PTHR14689:SF0 PHORBOL-ESTER_DAG-TYPE DOMAIN-CONTAINING PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 82 MONDO|Ensembl=ENSMODG00000027437.2|UniProtKB=F6SRY8 F6SRY8 GCNT2 PTHR19297:SF183 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER N-ACETYLLACTOSAMINIDE BETA-1,6-N-ACETYLGLUCOSAMINYL-TRANSFERASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;response to transforming growth factor beta#GO:0071559;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;signaling#GO:0023052 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000013963.4|UniProtKB=F6RS54 F6RS54 IRF1 PTHR11949:SF3 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000036487.1|UniProtKB=A0A5F8HDJ4 A0A5F8HDJ4 PTHR10649:SF3 ARYL HYDROCARBON RECEPTOR ARYL HYDROCARBON RECEPTOR REPRESSOR sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;nuclear receptor activity#GO:0004879;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000038839.1|UniProtKB=A0A5F8GGX0 A0A5F8GGX0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000017946.4|UniProtKB=F7E3E2 F7E3E2 EHD4 PTHR11216:SF57 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 4 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 organelle assembly#GO:0070925;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein localization to plasma membrane#GO:0072659;cell projection organization#GO:0030030;endocytic recycling#GO:0032456;endocytosis#GO:0006897;protein localization to cell periphery#GO:1990778;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;plasma membrane bounded cell projection organization#GO:0120036 recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;recycling endosome#GO:0055037;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000023987.2|UniProtKB=F7E8G5 F7E8G5 PTHR10026:SF70 CYCLIN CYCLIN-Q kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 kinase modulator#PC00140;kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000014342.3|UniProtKB=F6ULG7 F6ULG7 CARD19 PTHR34765:SF1 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 19 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 19 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000024213.2|UniProtKB=F6WFL8 F6WFL8 LOC100027512 PTHR26452:SF264 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014947.4|UniProtKB=H9H6Q5 H9H6Q5 LOC100030465 PTHR24257:SF16 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER NEUTROPHIL ELASTASE serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 response to stimulus#GO:0050896;cell motility#GO:0048870;endocytosis#GO:0006897;primary metabolic process#GO:0044238;localization#GO:0051179;protein metabolic process#GO:0019538;acute inflammatory response#GO:0002526;proteolysis#GO:0006508;immune system process#GO:0002376;inflammatory response#GO:0006954;cell migration#GO:0016477;response to stress#GO:0006950;immune response#GO:0006955;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;import into cell#GO:0098657;defense response#GO:0006952;metabolic process#GO:0008152;leukocyte migration#GO:0050900;phagocytosis#GO:0006909;transport#GO:0006810 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000009198.4|UniProtKB=F6Z016 F6Z016 SLC7A1 PTHR43243:SF28 INNER MEMBRANE TRANSPORTER YGJI-RELATED HIGH AFFINITY CATIONIC AMINO ACID TRANSPORTER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 amino acid transporter#PC00046;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000010028.4|UniProtKB=F6TUL0 F6TUL0 LOC100028992 PTHR11819:SF112 SOLUTE CARRIER FAMILY 5 GLUCOSE SENSOR PROTEIN SLC5A4-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 carbohydrate transport#GO:0008643;transport#GO:0006810;system process#GO:0003008;localization#GO:0051179;renal absorption#GO:0070293;import into cell#GO:0098657;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;D-glucose transmembrane transport#GO:1904659;renal system process#GO:0003014;cellular process#GO:0009987;import across plasma membrane#GO:0098739;multicellular organismal process#GO:0032501;carbohydrate transmembrane transport#GO:0034219 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000009214.3|UniProtKB=F7EEG0 F7EEG0 LOC100023139 PTHR26453:SF12 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027349.2|UniProtKB=K7E0B7 K7E0B7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000043686.1|UniProtKB=F6XXH2 F6XXH2 LOC100022456 PTHR26453:SF631 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040150.1|UniProtKB=A0A5F8HDT7 A0A5F8HDT7 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008916.2|UniProtKB=F7GL82 F7GL82 NMUR2 PTHR24243:SF14 G-PROTEIN COUPLED RECEPTOR NEUROMEDIN-U RECEPTOR 2 signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188 phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000045867.1|UniProtKB=A0A5F8H315 A0A5F8H315 RTF2 PTHR12775:SF0 PROTEIN C20ORF43 HOMOLOG REPLICATION TERMINATION FACTOR 2 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000027474.2|UniProtKB=A0A5F8G5P7 A0A5F8G5P7 ASL PTHR43814:SF1 ARGININOSUCCINATE LYASE ARGININOSUCCINATE LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 lyase#PC00144 Arginine biosynthesis#P02728>argininosuccinate lyase#P02841 MONDO|Ensembl=ENSMODG00000012680.4|UniProtKB=A0A5F8HBJ0 A0A5F8HBJ0 CCNE1 PTHR10177:SF71 CYCLINS G1_S-SPECIFIC CYCLIN-E1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;cell cycle process#GO:0022402;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;regulation of G1/S transition of mitotic cell cycle#GO:2000045;mitotic cell cycle phase transition#GO:0044772;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;positive regulation of cell cycle#GO:0045787;positive regulation of cell cycle G1/S phase transition#GO:1902808;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047;positive regulation of mitotic cell cycle#GO:0045931 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 p53 pathway#P00059>Cyclin E#P04610;Cell cycle#P00013>Cyclin E#P00483;Cell cycle#P00013>CdkC#P00489;p53 pathway feedback loops 2#P04398>cyclin E#P04664;Parkinson disease#P00049>Cyclin E#P01213 MONDO|Ensembl=ENSMODG00000021495.4|UniProtKB=F7G2S6 F7G2S6 CABLES1 PTHR22896:SF1 CDK5 AND ABL1 ENZYME SUBSTRATE 1 CDK5 AND ABL1 ENZYME SUBSTRATE 1 multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000018110.4|UniProtKB=F7FFA9 F7FFA9 COPS7A PTHR15350:SF7 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 COP9 SIGNALOSOME COMPLEX SUBUNIT 7A metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;post-translational protein modification#GO:0043687 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000015688.2|UniProtKB=A0A5F8HKB3 A0A5F8HKB3 SCARB1 PTHR11923:SF110 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 SCAVENGER RECEPTOR CLASS B MEMBER 1 protein-lipid complex binding#GO:0071814;low-density lipoprotein particle binding#GO:0030169;binding#GO:0005488;lipoprotein particle binding#GO:0071813;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;cargo receptor activity#GO:0038024 apoptotic cell clearance#GO:0043277;plasma lipoprotein particle clearance#GO:0034381;import into cell#GO:0098657;establishment of localization#GO:0051234;sterol transport#GO:0015918;phagocytosis#GO:0006909;transport#GO:0006810;lipid transport#GO:0006869;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;cholesterol efflux#GO:0033344;cellular process#GO:0009987;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;cell recognition#GO:0008037;endocytosis#GO:0006897;regulation of biological process#GO:0050789 plasma membrane raft#GO:0044853;membrane microdomain#GO:0098857;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane raft#GO:0045121;caveola#GO:0005901;membrane#GO:0016020;cell periphery#GO:0071944 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000024021.1|UniProtKB=F7GHG9 F7GHG9 RPRML PTHR28649:SF3 PROTEIN REPRIMO-RELATED REPRIMO-LIKE PROTEIN MONDO|Ensembl=ENSMODG00000044599.1|UniProtKB=A0A5F8HAY0 A0A5F8HAY0 PTHR23232:SF163 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000001721.3|UniProtKB=F6XGA5 F6XGA5 TNPO1 PTHR10527:SF21 IMPORTIN BETA TRANSPORTIN-1 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein localization to organelle#GO:0033365;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 MONDO|Ensembl=ENSMODG00000014085.3|UniProtKB=A0A5F8GI24 A0A5F8GI24 VGLL1 PTHR15950:SF20 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 1 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000020862.4|UniProtKB=F6R061 F6R061 BCL3 PTHR24118:SF51 POTE ANKYRIN DOMAIN B-CELL LYMPHOMA 3 PROTEIN transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859 MONDO|Ensembl=ENSMODG00000045315.1|UniProtKB=F6YJ16 F6YJ16 LOC100031267 PTHR26452:SF812 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AC2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000012887.4|UniProtKB=F6Z1A8 F6Z1A8 PTHR10682:SF9 POLY A POLYMERASE POLY(A) POLYMERASE ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000017549.4|UniProtKB=F7E0Z8 F7E0Z8 LHX3 PTHR24208:SF91 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000016415.2|UniProtKB=F7AT41 F7AT41 PTHR11620:SF106 60S RIBOSOMAL PROTEIN L23A LARGE RIBOSOMAL SUBUNIT PROTEIN UL23 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000018475.4|UniProtKB=A0A5F8G6R4 A0A5F8G6R4 DCHS1 PTHR24027:SF423 CADHERIN-23 PROTOCADHERIN-16 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;cell motility#GO:0048870;cell migration#GO:0016477 extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000019747.2|UniProtKB=F6WNQ1 F6WNQ1 S100Z PTHR11639:SF72 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-Z cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000018255.3|UniProtKB=F6PFV0 F6PFV0 PTHR10969:SF30 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN-LIKE 1 binding#GO:0005488;signaling receptor binding#GO:0005102;enzyme binding#GO:0019899;protein binding#GO:0005515;lipid binding#GO:0008289;GABA receptor binding#GO:0050811;phospholipid binding#GO:0005543;ubiquitin-like protein ligase binding#GO:0044389;ubiquitin protein ligase binding#GO:0031625 autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;response to stress#GO:0006950;response to nutrient levels#GO:0031667;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;cellular response to nutrient levels#GO:0031669;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411 autophagosome#GO:0005776;intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000007728.3|UniProtKB=A0A5F8HDK7 A0A5F8HDK7 L2HGDH PTHR43104:SF2 L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 metabolic process#GO:0008152;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000039077.1|UniProtKB=A0A5F8HHH9 A0A5F8HHH9 LOC100027339 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000935.4|UniProtKB=F7F7Z0 F7F7Z0 ATP10A PTHR24092:SF81 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE VA intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326 lipid transport#GO:0006869;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000009557.5|UniProtKB=F6QL97 F6QL97 PTHR23337:SF7 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 1 ATPASE MORC2 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000042152.1|UniProtKB=A0A5F8HCF2 A0A5F8HCF2 LOC100617529 PTHR26450:SF70 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR OLFR593 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004148.4|UniProtKB=F6RA61 F6RA61 CENPL PTHR31740:SF2 CENTROMERE PROTEIN L CENTROMERE PROTEIN L MONDO|Ensembl=ENSMODG00000009919.3|UniProtKB=F6R9D3 F6R9D3 TMIGD1 PTHR11640:SF157 NEPHRIN V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10 protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000018653.4|UniProtKB=A0A5F8HJ57 A0A5F8HJ57 POLR2D PTHR21297:SF0 DNA-DIRECTED RNA POLYMERASE II DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 translation initiation factor binding#GO:0031369;protein binding#GO:0005515;binding#GO:0005488 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367 protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 MONDO|Ensembl=ENSMODG00000047920.1|UniProtKB=A0A5F8GZY1 A0A5F8GZY1 monDomV1R1251 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000029707.2|UniProtKB=K7E4S3 K7E4S3 PTHR35442:SF1 TRANSMEMBRANE PROTEIN 249 CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT THETA MONDO|Ensembl=ENSMODG00000017903.4|UniProtKB=F7FGE7 F7FGE7 DERA PTHR10889:SF3 DEOXYRIBOSE-PHOSPHATE ALDOLASE DEOXYRIBOSE-PHOSPHATE ALDOLASE aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 nucleobase-containing small molecule catabolic process#GO:0034656;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;nucleobase-containing compound metabolic process#GO:0006139;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside catabolic process#GO:0009164 aldolase#PC00044;lyase#PC00144 MONDO|Ensembl=ENSMODG00000001726.5|UniProtKB=F6XG79 F6XG79 SETD1A PTHR45814:SF3 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1A protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone H3K4 methyltransferase activity#GO:0042800;lysine N-methyltransferase activity#GO:0016278;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993 organelle lumen#GO:0043233;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000040021.1|UniProtKB=F7BPK5 F7BPK5 PTHR11426:SF274 HISTONE H3 HISTONE H3-7 mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;kinetochore assembly#GO:0051382;nuclear division#GO:0000280;organelle localization#GO:0051640;organelle assembly#GO:0070925;organelle fission#GO:0048285;localization#GO:0051179;kinetochore organization#GO:0051383;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000023425.2|UniProtKB=F6ST12 F6ST12 ZSWIM1 PTHR31569:SF0 SWIM-TYPE DOMAIN-CONTAINING PROTEIN ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000006090.5|UniProtKB=F7FED8 F7FED8 ABL2 PTHR24418:SF87 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ABL2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;regulation of biological process#GO:0050789;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 MONDO|Ensembl=ENSMODG00000023551.2|UniProtKB=F7BQW3 F7BQW3 ZBTB6 PTHR24399:SF36 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 6 sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000047947.1|UniProtKB=A0A5F8HB47 A0A5F8HB47 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000014721.4|UniProtKB=A0A5F8HAC4 A0A5F8HAC4 ALKBH8 PTHR13069:SF21 ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 TRNA (CARBOXYMETHYLURIDINE(34)-5-O)-METHYLTRANSFERASE ALKBH8 tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;binding#GO:0005488;nucleic acid binding#GO:0003676;methyltransferase activity#GO:0008168 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000005884.4|UniProtKB=A0A5F8H6J4 A0A5F8H6J4 PDE6C PTHR11347:SF23 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA' hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;system process#GO:0003008;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;sensory perception#GO:0007600;nervous system process#GO:0050877;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;sensory perception of light stimulus#GO:0050953;regulation of cell communication#GO:0010646;visual perception#GO:0007601;regulation of cellular process#GO:0050794 hydrolase#PC00121;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000027485.2|UniProtKB=K7E5A6 K7E5A6 LOC103103493 PTHR47499:SF2 SERINE PROTEASE INHIBITOR KAZAL-TYPE 7 SPINK7 SERINE PROTEASE INHIBITOR KAZAL-TYPE 9 peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 regulation of proteolysis#GO:0030162;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of biological process#GO:0048519;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;negative regulation of metabolic process#GO:0009892;biological regulation#GO:0065007;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000005948.5|UniProtKB=F6WFZ8 F6WFZ8 PTHR10454:SF206 CASPASE CASPASE-6 cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 positive regulation of apoptotic process#GO:0043065;positive regulation of neuron apoptotic process#GO:0043525;regulation of apoptotic process#GO:0042981;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of neuron apoptotic process#GO:0043523;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;protease#PC00190 FAS signaling pathway#P00020>Caspase6#P00596;Huntington disease#P00029>Caspase 6#P00809;FAS signaling pathway#P00020>Pro-Caspase6#P00607 MONDO|Ensembl=ENSMODG00000037353.1|UniProtKB=A0A5F8H7H9 A0A5F8H7H9 PTHR36912:SF2 ANTIGEN 332, DBL-LIKE PROTEIN-RELATED ANTIGEN 332, DBL-LIKE PROTEIN MONDO|Ensembl=ENSMODG00000023856.3|UniProtKB=A0A5F8GHR3 A0A5F8GHR3 PTHR44427:SF13 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 4-RELATED cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000011178.4|UniProtKB=F6ZZ63 F6ZZ63 LOC100020231 PTHR24377:SF244 IP01015P-RELATED ZINC FINGER PROTEIN 623 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009503.3|UniProtKB=F7F9L2 F7F9L2 BTG1 PTHR22978:SF30 B-CELL TRANSLOCATION GENE PROTEIN BTG1 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;negative regulation of cell population proliferation#GO:0008285;negative regulation of biological process#GO:0048519 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000002876.4|UniProtKB=F7E1Z5 F7E1Z5 SH3RF1 PTHR14167:SF44 SH3 DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE SH3RF1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein-macromolecule adaptor activity#GO:0030674;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;molecular adaptor activity#GO:0060090 generation of neurons#GO:0048699;regulation of signaling#GO:0023051;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;cell differentiation#GO:0030154;regulation of MAPK cascade#GO:0043408;regulation of apoptotic process#GO:0042981;regulation of JNK cascade#GO:0046328;multicellular organism development#GO:0007275;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;nervous system development#GO:0007399;system development#GO:0048731;anatomical structure development#GO:0048856;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;cell motility#GO:0048870;regulation of cellular process#GO:0050794;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;neuron migration#GO:0001764;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;multicellular organismal process#GO:0032501;cell migration#GO:0016477 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020752.4|UniProtKB=F6ZZD6 F6ZZD6 TMPRSS11E PTHR24253:SF84 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 11E hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000015298.2|UniProtKB=A0A5F8HA42 A0A5F8HA42 APOM PTHR32028:SF1 APOLIPOPROTEIN M APOLIPOPROTEIN M molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;lipid localization#GO:0010876;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;cholesterol efflux#GO:0033344;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;lipid transport#GO:0006869;biological regulation#GO:0065007;transport#GO:0006810;sterol transport#GO:0015918;plasma lipoprotein particle clearance#GO:0034381;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;very-low-density lipoprotein particle#GO:0034361;plasma lipoprotein particle#GO:0034358;high-density lipoprotein particle#GO:0034364;extracellular region#GO:0005576;protein-lipid complex#GO:0032994;extracellular protein-containing complex#GO:0140392;lipoprotein particle#GO:1990777 apolipoprotein#PC00052;transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000046035.1|UniProtKB=A0A5F8GGW3 A0A5F8GGW3 PTHR24249:SF79 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 9 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000005958.4|UniProtKB=F6WF79 F6WF79 E2F5 PTHR12081:SF35 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F5 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000020396.3|UniProtKB=F7BZT7 F7BZT7 PTHR19282:SF455 TETRASPANIN TETRASPANIN-16 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000027717.1|UniProtKB=F6VKE6 F6VKE6 PTHR24393:SF126 ZINC FINGER PROTEIN RB-ASSOCIATED KRAB ZINC FINGER PROTEIN double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000011397.4|UniProtKB=A0A5F8GHD3 A0A5F8GHD3 ADAM11 PTHR11905:SF114 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 11 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000037380.1|UniProtKB=K7E1X4 K7E1X4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000025514.2|UniProtKB=F6VJC0 F6VJC0 PTHR35252:SF1 RETINITIS PIGMENTOSA 9 PROTEIN RETINITIS PIGMENTOSA 9 PROTEIN MONDO|Ensembl=ENSMODG00000028257.2|UniProtKB=K7E3R2 K7E3R2 PTHR46006:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A NEUROEPITHELIAL CELL-TRANSFORMING GENE 1 PROTEIN regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000041132.1|UniProtKB=A0A5F8GL90 A0A5F8GL90 GDF7 PTHR11848:SF160 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 7 cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165;renal system development#GO:0072001;kidney development#GO:0001822;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000015195.4|UniProtKB=F7BVR8 F7BVR8 PABIR2 PTHR22227:SF1 FAMILY WITH SEQUENCE SIMILARITY 122B ISOFORM X1 PABIR FAMILY MEMBER 2 enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;protein serine/threonine phosphatase inhibitor activity#GO:0004865;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857 biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of proteasomal protein catabolic process#GO:1901800;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000038513.1|UniProtKB=F6TER6 F6TER6 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000015182.4|UniProtKB=F7BW23 F7BW23 SND1 PTHR12302:SF2 EBNA2 BINDING PROTEIN P100 STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000043810.1|UniProtKB=A0A5F8HCU5 A0A5F8HCU5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000019036.3|UniProtKB=F7BKX1 F7BKX1 ASAH1 PTHR28583:SF1 ACID AMIDASE ACID CERAMIDASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000046107.1|UniProtKB=A0A5F8GS44 A0A5F8GS44 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000011979.4|UniProtKB=A0A5F8GXT3 A0A5F8GXT3 SIL1 PTHR19316:SF35 PROTEIN FOLDING REGULATOR NUCLEOTIDE EXCHANGE FACTOR SIL1 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000051322.1|UniProtKB=A0A5F8GNC6 A0A5F8GNC6 PTHR45737:SF6 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A MONDO|Ensembl=ENSMODG00000013076.4|UniProtKB=F7FBL9 F7FBL9 STPG1 PTHR21580:SF21 SHIPPO-1-RELATED O(6)-METHYLGUANINE-INDUCED APOPTOSIS 2 regulation of biological quality#GO:0065008;cellular component organization or biogenesis#GO:0071840;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;regulation of mitochondrial membrane permeability#GO:0046902;biological regulation#GO:0065007;regulation of membrane permeability#GO:0090559;cellular process#GO:0009987;cell death#GO:0008219;apoptotic process#GO:0006915;cellular component organization#GO:0016043;programmed cell death#GO:0012501;organelle organization#GO:0006996 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000006729.4|UniProtKB=F7CX37 F7CX37 CACNA1E PTHR45628:SF5 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT R-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1E monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836 trans-synaptic signaling#GO:0099537;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;calcium ion import#GO:0070509;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;calcium ion transmembrane transport#GO:0070588;inorganic ion import across plasma membrane#GO:0099587;signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;import across plasma membrane#GO:0098739;transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular process#GO:0009987;synaptic signaling#GO:0099536;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;cell-cell signaling#GO:0007267 transmembrane transporter complex#GO:1902495;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;cell body#GO:0044297;calcium channel complex#GO:0034704;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944 voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>Ca2+ channel#P01022;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ca2+channel#P00742;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041 MONDO|Ensembl=ENSMODG00000021054.3|UniProtKB=F6VJJ3 F6VJJ3 MRPS6 PTHR21011:SF17 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6 SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843 intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000013196.4|UniProtKB=F7FA67 F7FA67 TMX1 PTHR46107:SF2 DUMPY: SHORTER THAN WILD-TYPE THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 1 oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000010091.4|UniProtKB=F6XM69 F6XM69 MRPL49 PTHR13477:SF0 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L49 LARGE RIBOSOMAL SUBUNIT PROTEIN ML49 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000039281.1|UniProtKB=A0A5F8GNP8 A0A5F8GNP8 PTHR41694:SF8 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 11 POL PROTEIN-LIKE RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007387.4|UniProtKB=F6ZMP3 F6ZMP3 PTHR48488:SF1 INTERLEUKIN-22 INTERLEUKIN-22 receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 negative regulation of inflammatory response#GO:0050728;regulation of response to external stimulus#GO:0032101;negative regulation of defense response#GO:0031348;negative regulation of response to stimulus#GO:0048585;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of response to stress#GO:0080134;regulation of inflammatory response#GO:0050727;regulation of response to stimulus#GO:0048583;regulation of defense response#GO:0031347 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000041706.1|UniProtKB=A0A5F8H482 A0A5F8H482 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;signaling#GO:0023052;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000027781.2|UniProtKB=K7E3M2 K7E3M2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000021293.2|UniProtKB=F7GE02 F7GE02 DNAJC19 PTHR12763:SF56 FAMILY NOT NAMED MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM14 ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;mitochondrial transmembrane transport#GO:1990542;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein transport#GO:0015031 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;mitochondrial inner membrane#GO:0005743 MONDO|Ensembl=ENSMODG00000040423.1|UniProtKB=A0A5F8GYL5 A0A5F8GYL5 PTHR11346:SF80 GALECTIN GALECTIN-9B binding#GO:0005488;carbohydrate derivative binding#GO:0097367;carbohydrate binding#GO:0030246 negative regulation of multicellular organismal process#GO:0051241;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of T cell proliferation#GO:0042129;regulation of macromolecule metabolic process#GO:0060255;negative regulation of leukocyte cell-cell adhesion#GO:1903038;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;negative regulation of cell population proliferation#GO:0008285;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of biosynthetic process#GO:0009889;negative regulation of cell activation#GO:0050866;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;negative regulation of gene expression#GO:0010629;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of lymphocyte activation#GO:0051249;negative regulation of metabolic process#GO:0009892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of mononuclear cell proliferation#GO:0032944;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;regulation of T cell activation#GO:0050863;negative regulation of cell-cell adhesion#GO:0022408;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;regulation of leukocyte proliferation#GO:0070663;negative regulation of T cell proliferation#GO:0042130 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000028489.2|UniProtKB=K7E3J9 K7E3J9 EPB41L5 PTHR23280:SF15 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 5 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cell adhesion#GO:0030155;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of cell adhesion#GO:0045785;organelle organization#GO:0006996;cellular component organization#GO:0016043 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;cell projection membrane#GO:0031253;ruffle#GO:0001726;ruffle membrane#GO:0032587;leading edge membrane#GO:0031256 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000005128.4|UniProtKB=F7EQN9 F7EQN9 FBXO28 PTHR13252:SF9 F-BOX ONLY PROTEIN 28 F-BOX ONLY PROTEIN 28 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211 MONDO|Ensembl=ENSMODG00000020597.4|UniProtKB=F7A071 F7A071 PTHR45688:SF1 FAMILY NOT NAMED ETHANOLAMINE-PHOSPHATE PHOSPHO-LYASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 MONDO|Ensembl=ENSMODG00000010869.4|UniProtKB=F7FW45 F7FW45 LOC100017583 PTHR48001:SF42 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1P1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027766.2|UniProtKB=K7E510 K7E510 SLC39A11 PTHR11040:SF211 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP11 metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915 cellular process#GO:0009987;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000046199.1|UniProtKB=A0A5F8GS97 A0A5F8GS97 PTHR23048:SF63 MYOSIN LIGHT CHAIN 1, 3 CALMODULIN-LIKE 5 actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000048401.1|UniProtKB=A0A5F8HJ08 A0A5F8HJ08 ODF4 PTHR10671:SF94 EPITHELIAL MEMBRANE PROTEIN-RELATED OUTER DENSE FIBER PROTEIN 4 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000012683.3|UniProtKB=F6VG70 F6VG70 NKX2-8 PTHR24340:SF27 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.8 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000003485.4|UniProtKB=F7CSQ9 F7CSQ9 HGFAC PTHR24264:SF43 TRYPSIN-RELATED HEPATOCYTE GROWTH FACTOR ACTIVATOR SERINE PROTEASE catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 hemostasis#GO:0007599;primary metabolic process#GO:0044238;zymogen activation#GO:0031638;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;proteolysis#GO:0006508;protein metabolic process#GO:0019538;wound healing#GO:0042060;regulation of biological quality#GO:0065008;response to stress#GO:0006950;response to wounding#GO:0009611;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;coagulation#GO:0050817;protein maturation#GO:0051604;gene expression#GO:0010467;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;biological regulation#GO:0065007;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;blood coagulation#GO:0007596 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000008556.3|UniProtKB=F7DGJ9 F7DGJ9 RAB2A PTHR47979:SF12 DRAB11-RELATED RAS-RELATED PROTEIN RAB-2A carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000000589.3|UniProtKB=F6TRQ7 F6TRQ7 PTHR10044:SF79 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme regulator activity#GO:0030234;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of protein ubiquitination#GO:0031396;regulation of protein modification process#GO:0031399;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell cycle#GO:0051726 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 Apoptosis signaling pathway#P00006>c-IAP1,2#P00264;CCKR signaling map#P06959>BIRC2#G07278 MONDO|Ensembl=ENSMODG00000044411.1|UniProtKB=F6Q2K6 F6Q2K6 LOC100618720 PTHR26450:SF414 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR FAMILY 56 SUBFAMILY A MEMBER 9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000033369.2|UniProtKB=A0A5F8G662 A0A5F8G662 PTHR32414:SF2 NEUROMEDIN-S NEUROMEDIN-S MONDO|Ensembl=ENSMODG00000006632.4|UniProtKB=A0A5F8GRB8 A0A5F8GRB8 SH3GLB2 PTHR14167:SF68 SH3 DOMAIN-CONTAINING ENDOPHILIN-B2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007734.4|UniProtKB=F7C474 F7C474 EXOC5 PTHR12100:SF0 SEC10 EXOCYST COMPLEX COMPONENT 5 localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;secretion by cell#GO:0032940;exocytosis#GO:0006887;transport#GO:0006810;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987 vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000010850.4|UniProtKB=F7AR53 F7AR53 RNF138 PTHR46968:SF2 E3 UBIQUITIN-PROTEIN LIGASE RNF138 E3 UBIQUITIN-PROTEIN LIGASE RNF138 DNA binding#GO:0003677;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;nucleic acid binding#GO:0003676;binding#GO:0005488;acyltransferase activity#GO:0016746;single-stranded DNA binding#GO:0003697;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729;DNA damage response#GO:0006974;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;double-strand break repair via single-strand annealing#GO:0045002;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;site of double-strand break#GO:0035861;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000038367.1|UniProtKB=A0A5F8HF59 A0A5F8HF59 PTHR23239:SF164 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 15 structural molecule activity#GO:0005198 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular process#GO:0009987;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000020686.4|UniProtKB=F7DKQ2 F7DKQ2 H2AZ1 PTHR23430:SF47 HISTONE H2A HISTONE H2A.Z structural molecule activity#GO:0005198 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of cellular process#GO:0048523;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000021314.4|UniProtKB=F7G389 F7G389 NAALADL2 PTHR10404:SF32 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE INACTIVE N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE-LIKE PROTEIN 2 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;peptidase activity#GO:0008233 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000002110.4|UniProtKB=F6UGP3 F6UGP3 MTRR PTHR19384:SF84 NITRIC OXIDE SYNTHASE-RELATED METHIONINE SYNTHASE REDUCTASE oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;oxidoreductase activity, acting on metal ions#GO:0016722;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;aspartate family amino acid biosynthetic process#GO:0009067;homocysteine metabolic process#GO:0050667;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000050529.1|UniProtKB=A0A5F8HJ56 A0A5F8HJ56 PTHR45616:SF69 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN 5-RELATED structural molecule activity#GO:0005198 intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;skin development#GO:0043588;cytoskeleton organization#GO:0007010;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;animal organ development#GO:0048513;developmental process#GO:0032502;epidermis development#GO:0008544 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000004159.5|UniProtKB=F6TZF0 F6TZF0 ZNF3 PTHR23232:SF140 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 11-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000012788.4|UniProtKB=F6S0P8 F6S0P8 PPP1R1B PTHR15417:SF2 PROTEIN PHOSPHATASE INHIBITOR AND DOPAMINE- AND CAMP-REGULATED NEURONAL PHOSPHOPROTEIN PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1B protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857;phosphatase regulator activity#GO:0019208;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888 intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to nitrogen compound#GO:1901699;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cell body#GO:0044297;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477 protein-binding activity modulator#PC00095;phosphatase inhibitor#PC00183;phosphatase modulator#PC00184 Nicotine pharmacodynamics pathway#P06587>PPP1R1B#P06589;Dopamine receptor mediated signaling pathway#P05912>DARPP-32#P05950 MONDO|Ensembl=ENSMODG00000047195.1|UniProtKB=A0A5F8GVI8 A0A5F8GVI8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000047454.1|UniProtKB=A0A5F8GYI3 A0A5F8GYI3 UTS2 PTHR14447:SF0 UROTENSIN 2 UROTENSIN-2 circulatory system process#GO:0003013;regulation of blood pressure#GO:0008217;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;system process#GO:0003008;multicellular organismal process#GO:0032501;blood circulation#GO:0008015 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000012852.4|UniProtKB=F7D6T5 F7D6T5 PITHD1 PTHR12175:SF7 AD039 HT014 THIOREDOXIN FAMILY TRP26 PITH DOMAIN-CONTAINING PROTEIN 1 positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of cell development#GO:0060284;positive regulation of biological process#GO:0048518;positive regulation of myeloid cell differentiation#GO:0045639;positive regulation of cellular process#GO:0048522;regulation of hemopoiesis#GO:1903706;regulation of myeloid cell differentiation#GO:0045637;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000008224.4|UniProtKB=F7FCP4 F7FCP4 NTRK2 PTHR24416:SF136 TYROSINE-PROTEIN KINASE RECEPTOR BDNF_NT-3 GROWTH FACTORS RECEPTOR catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;response to growth factor#GO:0070848;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;cellular response to nerve growth factor stimulus#GO:1990090;multicellular organism development#GO:0007275;neurogenesis#GO:0022008 postsynapse#GO:0098794;dendritic spine#GO:0043197;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron projection terminus#GO:0044306;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;neuron spine#GO:0044309;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;membrane#GO:0016020;presynapse#GO:0098793;neuron projection#GO:0043005;cell periphery#GO:0071944;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;signaling receptor complex#GO:0043235;cell junction#GO:0030054;axon terminus#GO:0043679 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004130.4|UniProtKB=F6UVL8 F6UVL8 KLHL20 PTHR24412:SF508 KELCH PROTEIN KELCH-LIKE PROTEIN 20 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;post-Golgi vesicle-mediated transport#GO:0006892;protein metabolic process#GO:0019538;cellular localization#GO:0051641;localization#GO:0051179;Golgi to endosome transport#GO:0006895;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;cytosolic transport#GO:0016482;catabolic process#GO:0009056;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;proteasomal protein catabolic process#GO:0010498;vesicle-mediated transport#GO:0016192 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;membraneless organelle#GO:0043228;transferase complex#GO:1990234;Golgi apparatus#GO:0005794;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;Golgi apparatus subcompartment#GO:0098791 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000016304.4|UniProtKB=F7A690 F7A690 SLC9A8 PTHR10110:SF191 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 8 monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;plasma membrane#GO:0005886;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000010782.4|UniProtKB=A0A5F8HET8 A0A5F8HET8 EYA3 PTHR10190:SF5 EYES ABSENT PROTEIN PHOSPHATASE EYA3 hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 positive regulation of DNA repair#GO:0045739;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;developmental process#GO:0032502;regulation of response to stress#GO:0080134;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;positive regulation of DNA metabolic process#GO:0051054;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000037179.1|UniProtKB=A0A5F8HF23 A0A5F8HF23 PTHR24390:SF290 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 184 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006534.4|UniProtKB=F7CDM6 F7CDM6 NIPAL2 PTHR12570:SF16 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED NIPA-LIKE PROTEIN 2 establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;magnesium ion transport#GO:0015693;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000002223.4|UniProtKB=F7DFZ1 F7DFZ1 UBR7 PTHR13513:SF9 E3 UBIQUITIN-PROTEIN LIGASE UBR7 E3 UBIQUITIN-PROTEIN LIGASE UBR7-RELATED protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000007470.2|UniProtKB=F7DAF3 F7DAF3 LOC100029231 PTHR24242:SF388 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000020433.6|UniProtKB=F7AR81 F7AR81 ZNF532 PTHR47222:SF3 ZINC FINGER PROTEIN 532-RELATED ZINC FINGER PROTEIN 532 MONDO|Ensembl=ENSMODG00000018955.4|UniProtKB=F7G0F4 F7G0F4 SYNPO2 PTHR24217:SF9 PUTATIVE-RELATED SYNAPTOPODIN-2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;positive regulation of actin filament bundle assembly#GO:0032233;regulation of actin filament-based process#GO:0032970;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;regulation of cytoskeleton organization#GO:0051493;regulation of cell communication#GO:0010646;muscle cell development#GO:0055001;regulation of supramolecular fiber organization#GO:1902903;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;regulation of small GTPase mediated signal transduction#GO:0051056;cellular anatomical entity morphogenesis#GO:0032989;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;actomyosin structure organization#GO:0031032;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;regulation of organelle organization#GO:0033043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of organelle organization#GO:0010638;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130 actin cytoskeleton#GO:0015629;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512;myofibril#GO:0030016;actin filament bundle#GO:0032432;actomyosin#GO:0042641;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;I band#GO:0031674;stress fiber#GO:0001725;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;sarcomere#GO:0030017 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000008120.4|UniProtKB=F7FV29 F7FV29 WDR74 PTHR16038:SF4 NOP SEVEN ASSOCIATED PROTEIN 1 WD REPEAT-CONTAINING PROTEIN 74 metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000043140.1|UniProtKB=A0A5F8G850 A0A5F8G850 COASY PTHR10695:SF60 DEPHOSPHO-COA KINASE-RELATED BIFUNCTIONAL COENZYME A SYNTHASE adenylyltransferase activity#GO:0070566;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 kinase#PC00137;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000005215.4|UniProtKB=F7A1V0 F7A1V0 GDAP2 PTHR11106:SF72 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 2 MONDO|Ensembl=ENSMODG00000006906.2|UniProtKB=F6PTV4 F6PTV4 PTHR11829:SF372 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN I2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000047285.1|UniProtKB=A0A5F8GVI0 A0A5F8GVI0 MGAT4C PTHR12062:SF14 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE C acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 transferase#PC00220 MONDO|Ensembl=ENSMODG00000016700.3|UniProtKB=F7D2H2 F7D2H2 RAB40C PTHR47980:SF2 LD44762P RAS-RELATED PROTEIN RAB-40C molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein metabolic process#GO:0019538;secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;export from cell#GO:0140352;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;exocytosis#GO:0006887;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;transport#GO:0006810;vesicle-mediated transport#GO:0016192;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000010528.4|UniProtKB=F7D654 F7D654 WDFY2 PTHR46189:SF3 LD41958P WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 2 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of fat cell differentiation#GO:0045600;positive regulation of developmental process#GO:0051094;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769 MONDO|Ensembl=ENSMODG00000003651.5|UniProtKB=F7AZT2 F7AZT2 COMP PTHR10199:SF88 THROMBOSPONDIN CARTILAGE OLIGOMERIC MATRIX PROTEIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;connective tissue development#GO:0061448;tissue development#GO:0009888;anatomical structure development#GO:0048856 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000008987.4|UniProtKB=F7BQF2 F7BQF2 TNMD PTHR14064:SF3 CHONDROMODULIN-RELATED TENOMODULIN regulation of cell population proliferation#GO:0042127;negative regulation of angiogenesis#GO:0016525;regulation of anatomical structure morphogenesis#GO:0022603;regulation of angiogenesis#GO:0045765;negative regulation of cellular process#GO:0048523;regulation of vasculature development#GO:1901342;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;negative regulation of cell population proliferation#GO:0008285;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026 MONDO|Ensembl=ENSMODG00000023368.3|UniProtKB=A0A5F8GHV5 A0A5F8GHV5 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000017041.4|UniProtKB=H9H728 H9H728 KCNJ4 PTHR11767:SF53 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 4 ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular process#GO:0009987;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000013760.4|UniProtKB=A0A5F8GAD1 A0A5F8GAD1 SIDT2 PTHR12185:SF16 SID1 TRANSMEMBRANE FAMILY MEMEBER SID1 TRANSMEMBRANE FAMILY MEMBER 2 transmembrane transporter activity#GO:0022857;double-stranded RNA binding#GO:0003725;transporter activity#GO:0005215;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;nucleobase-containing compound transmembrane transporter activity#GO:0015932 macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;transport#GO:0006810;localization#GO:0051179;nucleic acid transport#GO:0050657;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000017244.4|UniProtKB=F6TLC5 F6TLC5 MAN1B1 PTHR11742:SF55 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000000384.3|UniProtKB=F6R8I7 F6R8I7 OXER1 PTHR46048:SF1 HYDROXYCARBOXYLIC ACID RECEPTOR 2 OXOEICOSANOID RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000002039.4|UniProtKB=F6QCU8 F6QCU8 NSUN2 PTHR22808:SF31 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING RNA CYTOSINE-C(5)-METHYLTRANSFERASE NSUN2-RELATED rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;methylation#GO:0032259;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;tRNA wobble base modification#GO:0002097;ribonucleoprotein complex biogenesis#GO:0022613;tRNA modification#GO:0006400;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;tRNA processing#GO:0008033;cellular process#GO:0009987;tRNA methylation#GO:0030488;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;protein-RNA complex assembly#GO:0022618;mitochondrial large ribosomal subunit assembly#GO:1902775;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;mitochondrial ribosome assembly#GO:0061668;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;ribosomal large subunit assembly#GO:0000027;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000005908.4|UniProtKB=F6XCX6 F6XCX6 DNAJC11 PTHR44157:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 11 DNAJ HOMOLOG SUBFAMILY C MEMBER 11 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;mitochondrion organization#GO:0007005;membrane organization#GO:0061024 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000018913.4|UniProtKB=F7C759 F7C759 BLTP1 PTHR31640:SF1 TRANSMEMBRANE PROTEIN KIAA1109 BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 1 synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;synaptic vesicle endocytosis#GO:0048488;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;cellular localization#GO:0051641;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810 MONDO|Ensembl=ENSMODG00000027725.2|UniProtKB=K7E5U3 K7E5U3 PTHR31770:SF12 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER TAFA CHEMOKINE LIKE FAMILY MEMBER 3 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083;chemokine#PC00074 MONDO|Ensembl=ENSMODG00000004395.4|UniProtKB=A0A5F8HCV6 A0A5F8HCV6 REXO1 PTHR12801:SF62 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 1 HOMOLOG hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 exoribonuclease#PC00099;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000045675.1|UniProtKB=A0A5F8GJ42 A0A5F8GJ42 EVA1A PTHR48422:SF1 PROTEIN EVA-1 HOMOLOG B-RELATED PROTEIN EVA-1 HOMOLOG A intracellular signal transduction#GO:0035556;process utilizing autophagic mechanism#GO:0061919;cell communication#GO:0007154;metabolic process#GO:0008152;signaling#GO:0023052;biological regulation#GO:0065007;TOR signaling#GO:0031929;catabolic process#GO:0009056;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;autophagy#GO:0006914;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000043900.1|UniProtKB=A0A5F8H8D2 A0A5F8H8D2 POLR3K PTHR11239:SF12 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10 catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;DNA-templated transcription termination#GO:0006353;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase III complex#GO:0005666;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000009262.5|UniProtKB=F6UKK9 F6UKK9 USPL1 PTHR15294:SF3 RETINOVIN-RELATED SUMO-SPECIFIC ISOPEPTIDASE USPL1 protein binding#GO:0005515;binding#GO:0005488 post-translational protein modification#GO:0043687;protein modification process#GO:0036211;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule modification#GO:0043412;nucleus organization#GO:0006997;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000001004.4|UniProtKB=A0A5F8G8C1 A0A5F8G8C1 CNGA3 PTHR45638:SF6 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL ALPHA-3 transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;nucleotide binding#GO:0000166;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;channel activity#GO:0015267;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;heterocyclic compound binding#GO:1901363;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;purine ribonucleotide binding#GO:0032555;gated channel activity#GO:0022836;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;monoatomic cation transmembrane transporter activity#GO:0008324 system process#GO:0003008;animal organ development#GO:0048513;establishment of localization#GO:0051234;multicellular organism development#GO:0007275;transport#GO:0006810;developmental process#GO:0032502;sensory perception of chemical stimulus#GO:0007606;sensory organ development#GO:0007423;retina development in camera-type eye#GO:0060041;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;multicellular organismal process#GO:0032501;cellular process#GO:0009987;sensory system development#GO:0048880;eye development#GO:0001654;monoatomic ion transport#GO:0006811;system development#GO:0048731;anatomical structure development#GO:0048856;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;visual system development#GO:0150063 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 ligand-gated ion channel#PC00141;ion channel#PC00133 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 MONDO|Ensembl=ENSMODG00000002512.4|UniProtKB=F7B8W6 F7B8W6 LOC100016794 PTHR23220:SF118 INTEGRIN ALPHA INTEGRIN SUBUNIT ALPHA D signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154 integrin complex#GO:0008305;signaling receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797 cell adhesion molecule#PC00069;integrin#PC00126 MONDO|Ensembl=ENSMODG00000001778.4|UniProtKB=F6WJ91 F6WJ91 KLHDC8A PTHR46260:SF1 RING-TYPE DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 8A MONDO|Ensembl=ENSMODG00000006966.4|UniProtKB=F6QV92 F6QV92 MTERF3 PTHR13068:SF194 CGI-12 PROTEIN-RELATED TRANSCRIPTION TERMINATION FACTOR 3, MITOCHONDRIAL cellular component assembly#GO:0022607;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of metabolic process#GO:0009892;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;mitochondrial ribosome assembly#GO:0061668;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;organelle assembly#GO:0070925 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000012200.3|UniProtKB=K7E1A0 K7E1A0 NGFR PTHR46605:SF3 TUMOR NECROSIS FACTOR RECEPTOR TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16 coreceptor activity#GO:0015026;signaling receptor activity#GO:0038023;death receptor activity#GO:0005035;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;growth factor binding#GO:0019838 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;intracellular signal transduction#GO:0035556 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008720.4|UniProtKB=F6PVA4 F6PVA4 BARX1 PTHR24330:SF12 HOMEOBOX PROTEIN BARH-LIKE HOMEOBOX PROTEIN BARH-LIKE 1 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000023870.3|UniProtKB=F7GJ24 F7GJ24 LOC130458234 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000038890.1|UniProtKB=A0A5F8GIK9 A0A5F8GIK9 LOC100019747 PTHR48002:SF76 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C11 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000051010.1|UniProtKB=K7E4W1 K7E4W1 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000012289.4|UniProtKB=F7GF46 F7GF46 HSPD1 PTHR45633:SF56 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lymphocyte activation#GO:0046649;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;protein maturation#GO:0051604;immune system process#GO:0002376;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular localization#GO:0051641;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;apoptotic process#GO:0006915;mitochondrial transport#GO:0006839;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;protein folding#GO:0006457;intracellular transport#GO:0046907;transport#GO:0006810;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;biosynthetic process#GO:0009058;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;cellular response to topologically incorrect protein#GO:0035967;positive regulation of lymphocyte activation#GO:0051251;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;positive regulation of type I interferon production#GO:0032481;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;metabolic process#GO:0008152;positive regulation of leukocyte activation#GO:0002696;positive regulation of cell-cell adhesion#GO:0022409;response to stress#GO:0006950;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;regulation of multicellular organismal process#GO:0051239;cellular response to stress#GO:0033554;response to unfolded protein#GO:0006986;positive regulation of metabolic process#GO:0009893;regulation of leukocyte activation#GO:0002694;T cell activation#GO:0042110;cellular component organization#GO:0016043;regulation of cell activation#GO:0050865;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte cell-cell adhesion#GO:1903037;establishment of localization#GO:0051234;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;mitochondrial protein import pathway#GO:7770058;cellular response to unfolded protein#GO:0034620;cell activation#GO:0001775;positive regulation of biosynthetic process#GO:0009891;localization#GO:0051179;protein metabolic process#GO:0019538;leukocyte activation#GO:0045321;positive regulation of cell adhesion#GO:0045785;cell death#GO:0008219;positive regulation of cytokine production#GO:0001819 organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;cytoplasm#GO:0005737;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000046223.1|UniProtKB=A0A5F8GNR1 A0A5F8GNR1 ANKRD10 PTHR24203:SF14 ANKYRIN REPEAT FAMILY PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 10 MONDO|Ensembl=ENSMODG00000006940.4|UniProtKB=F6RGF4 F6RGF4 PTDSS1 PTHR15362:SF15 PHOSPHATIDYLINOSITOL SYNTHASE PHOSPHATIDYLSERINE SYNTHASE 1 transferase#PC00220 MONDO|Ensembl=ENSMODG00000040929.1|UniProtKB=A0A5F8GKB9 A0A5F8GKB9 PTHR24637:SF421 COLLAGEN SCAVENGER RECEPTOR CLASS A MEMBER 3 MONDO|Ensembl=ENSMODG00000007305.3|UniProtKB=F7FBR7 F7FBR7 MIF4GD PTHR23254:SF17 EIF4G DOMAIN PROTEIN MIF4G DOMAIN-CONTAINING PROTEIN translation regulator activity#GO:0045182 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of translational initiation#GO:0006446 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000015815.3|UniProtKB=F7FE46 F7FE46 HADHA PTHR43612:SF3 TRIFUNCTIONAL ENZYME SUBUNIT ALPHA TRIFUNCTIONAL ENZYME SUBUNIT ALPHA, MITOCHONDRIAL transferase complex#GO:1990234;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000003302.4|UniProtKB=F7EFR2 F7EFR2 EPB41L4B PTHR23280:SF18 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 4B actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of cell adhesion#GO:0045785;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;organelle organization#GO:0006996;actomyosin structure organization#GO:0031032;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cell adhesion#GO:0030155 cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000018519.4|UniProtKB=A0A5F8HLK2 A0A5F8HLK2 SLC38A4 PTHR22950:SF222 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 4 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;transport#GO:0006810;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;organic acid transport#GO:0015849 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;amino acid transporter#PC00046 MONDO|Ensembl=ENSMODG00000016628.4|UniProtKB=F6YMM2 F6YMM2 AIPL1 PTHR11242:SF2 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED ARYL-HYDROCARBON-INTERACTING PROTEIN-LIKE 1 primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;cellular anatomical structure#GO:0110165 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000001741.3|UniProtKB=F6WZX7 F6WZX7 TRIB1 PTHR22961:SF17 SER/THR PROTEIN KINASE-TRB TRIBBLES HOMOLOG 1 protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of metabolic process#GO:0009893;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of protein metabolic process#GO:0051247;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000013022.3|UniProtKB=F7BP44 F7BP44 KLHDC8B PTHR46260:SF2 RING-TYPE DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 8B cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell division#GO:0051301;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;cytokinesis#GO:0000910;nuclear division#GO:0000280;cytokinetic process#GO:0032506;cytoskeleton-dependent cytokinesis#GO:0061640;organelle fission#GO:0048285;mitotic cytokinetic process#GO:1902410;organelle organization#GO:0006996;cellular process#GO:0009987;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047 membrane#GO:0016020;midbody#GO:0030496;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000023366.2|UniProtKB=F6ZDK4 F6ZDK4 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000018150.4|UniProtKB=F7CWR4 F7CWR4 EPHA7 PTHR46877:SF9 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 7 catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007 cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004041.2|UniProtKB=F7CLT1 F7CLT1 APRT PTHR32315:SF3 ADENINE PHOSPHORIBOSYLTRANSFERASE ADENINE PHOSPHORIBOSYLTRANSFERASE pentosyltransferase activity#GO:0016763;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;cation binding#GO:0043169;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;glycosyltransferase activity#GO:0016757;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleobase metabolic process#GO:0009112;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220 Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphoribosyl transferase#P02810 MONDO|Ensembl=ENSMODG00000016083.4|UniProtKB=F7FZ70 F7FZ70 SLC16A9 PTHR11360:SF158 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 9 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;monocarboxylic acid transmembrane transporter activity#GO:0008028 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000005295.3|UniProtKB=F7E6L5 F7E6L5 DUS2 PTHR45936:SF1 TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000039028.1|UniProtKB=A0A5F8H7G4 A0A5F8H7G4 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000047252.1|UniProtKB=A0A5F8HKX0 A0A5F8HKX0 PARVB PTHR12114:SF7 PARVIN BETA-PARVIN protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 regulation of biological process#GO:0050789;lamellipodium assembly#GO:0030032;regulation of cell shape#GO:0008360;cellular component organization#GO:0016043;regulation of developmental process#GO:0050793;cell projection organization#GO:0030030;actin cytoskeleton organization#GO:0030036;cell adhesion#GO:0007155;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;regulation of biological quality#GO:0065008;cell-substrate adhesion#GO:0031589;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;substrate adhesion-dependent cell spreading#GO:0034446;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603 membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;lamellipodium#GO:0030027;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell leading edge#GO:0031252;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell-substrate junction#GO:0030055;cell projection#GO:0042995;focal adhesion#GO:0005925;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;actin and actin related protein#PC00039 Integrin signalling pathway#P00034>Parvin#P00945 MONDO|Ensembl=ENSMODG00000028865.2|UniProtKB=A0A5F8GQJ7 A0A5F8GQJ7 IL7 PTHR48492:SF1 INTERLEUKIN-7 INTERLEUKIN-7 cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;response to peptide#GO:1901652;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;signal transduction#GO:0007165;cellular process#GO:0009987;interleukin-7-mediated signaling pathway#GO:0038111;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Interleukin signaling pathway#P00036>Interleukin#P00970 MONDO|Ensembl=ENSMODG00000051302.1|UniProtKB=A0A5F8H316 A0A5F8H316 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000024201.2|UniProtKB=F6SM42 F6SM42 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000038891.1|UniProtKB=A0A5F8H3X4 A0A5F8H3X4 LOC100027216 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000006.3|UniProtKB=F6SJ26 F6SJ26 INAVA PTHR16093:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 120 FAMILY MEMBER INNATE IMMUNITY ACTIVATOR PROTEIN regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;cellular component organization#GO:0016043;adherens junction organization#GO:0034332;regulation of protein modification process#GO:0031399;cell-cell junction maintenance#GO:0045217;cellular component organization or biogenesis#GO:0071840;regulation of protein ubiquitination#GO:0031396;cell-cell junction organization#GO:0045216;biological regulation#GO:0065007;positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 MONDO|Ensembl=ENSMODG00000019217.4|UniProtKB=F6ZHW3 F6ZHW3 CDC42SE2 PTHR13502:SF4 CDC42 SMALL EFFECTOR PROTEIN HOMOLOG CDC42 SMALL EFFECTOR PROTEIN 2 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000007824.4|UniProtKB=F7ETL5 F7ETL5 CSPP1 PTHR21616:SF2 CENTROSOME SPINDLE POLE ASSOCIATED PROTEIN CENTROSOME AND SPINDLE POLE-ASSOCIATED PROTEIN 1 positive regulation of cell cycle process#GO:0090068;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;positive regulation of cell cycle#GO:0045787;regulation of cellular process#GO:0050794;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 centromere DNA-binding protein#PC00071 MONDO|Ensembl=ENSMODG00000015312.4|UniProtKB=A0A5F8GHC2 A0A5F8GHC2 POT1 PTHR14513:SF0 PROTECTION OF TELOMERES 1 PROTECTION OF TELOMERES PROTEIN 1 enzyme inhibitor activity#GO:0004857;telomeric repeat DNA binding#GO:0042162;molecular function regulator activity#GO:0098772;sequence-specific DNA binding#GO:0043565;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488;molecular function inhibitor activity#GO:0140678;DNA binding#GO:0003677;enzyme regulator activity#GO:0030234 DNA metabolic process#GO:0006259;regulation of chromosome organization#GO:0033044;metabolic process#GO:0008152;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;regulation of telomere maintenance#GO:0032204;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of telomere maintenance via telomere lengthening#GO:1904356;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;telomere capping#GO:0016233;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;telomere organization#GO:0032200;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128 chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;nuclear telomere cap complex#GO:0000783;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000003979.4|UniProtKB=F7F909 F7F909 CNOT6 PTHR12121:SF33 CARBON CATABOLITE REPRESSOR PROTEIN 4 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6 3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;CCR4-NOT complex#GO:0030014;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000012402.3|UniProtKB=F6PMY7 F6PMY7 FAM78A PTHR31655:SF3 PROTEIN FAM78A PROTEIN FAM78A MONDO|Ensembl=ENSMODG00000020225.3|UniProtKB=F7FXI1 F7FXI1 LOC100013357 PTHR21502:SF2 ZINC FINGER PROTEIN DZIP1 RILP-LIKE PROTEIN 2 binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;protein binding#GO:0005515 cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;cilium#GO:0005929;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000002374.3|UniProtKB=F7G310 F7G310 ST3GAL6 PTHR13713:SF8 SIALYLTRANSFERASE TYPE 2 LACTOSAMINE ALPHA-2,3-SIALYLTRANSFERASE sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000005413.4|UniProtKB=F7DUR9 F7DUR9 BFSP1 PTHR14069:SF0 FILENSIN FILENSIN structural molecule activity#GO:0005198 cell development#GO:0048468;visual system development#GO:0150063;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;sensory system development#GO:0048880;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;sensory organ development#GO:0007423;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000013030.4|UniProtKB=F7BNK8 F7BNK8 FERMT2 PTHR16160:SF11 FERMITIN 2-RELATED FERMITIN FAMILY HOMOLOG 2 integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;anchoring junction#GO:0070161 MONDO|Ensembl=ENSMODG00000009008.4|UniProtKB=A0A5F8H1I8 A0A5F8H1I8 PCDH19 PTHR24028:SF40 CADHERIN-87A PROTOCADHERIN-19 cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000008391.4|UniProtKB=F7A4H4 F7A4H4 RRM1 PTHR11573:SF6 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 biosynthetic process#GO:0009058;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;oxidoreductase complex#GO:1990204;cytosol#GO:0005829;catalytic complex#GO:1902494 oxidoreductase#PC00176;reductase#PC00198 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo purine biosynthesis#P02738>GDP reductase#P02909;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921 MONDO|Ensembl=ENSMODG00000050463.1|UniProtKB=A0A5F8GZ34 A0A5F8GZ34 PTHR13030:SF8 NUDIX HYDROLASE ADP-RIBOSE PYROPHOSPHATASE hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000028756.2|UniProtKB=K7E537 K7E537 CD74 PTHR14093:SF17 HLA CLASS II GAMMA CHAIN HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;MHC protein binding#GO:0042287;binding#GO:0005488;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515 positive regulation of signal transduction#GO:0009967;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of immune response#GO:0050776;regulation of apoptotic signaling pathway#GO:2001233;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;negative regulation of cellular process#GO:0048523;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;regulation of biosynthetic process#GO:0009889;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;response to stimulus#GO:0050896;negative regulation of signaling#GO:0023057;immune system process#GO:0002376;regulation of cytokine production involved in immune response#GO:0002718;regulation of signaling#GO:0023051;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of cell communication#GO:0010648;positive regulation of immune system process#GO:0002684;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;lymphocyte activation#GO:0046649;positive regulation of macromolecule metabolic process#GO:0010604;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of signal transduction#GO:0009968;leukocyte activation involved in immune response#GO:0002366;regulation of cytokine-mediated signaling pathway#GO:0001959;leukocyte activation#GO:0045321;regulation of intrinsic apoptotic signaling pathway#GO:2001242;positive regulation of cell communication#GO:0010647;positive regulation of cytokine production#GO:0001819;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cell activation#GO:0001775;positive regulation of biosynthetic process#GO:0009891;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of apoptotic process#GO:0043066;regulation of signal transduction#GO:0009966;regulation of response to stress#GO:0080134;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of programmed cell death#GO:0043067;T cell activation#GO:0042110;regulation of intracellular signal transduction#GO:1902531;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of cytokine-mediated signaling pathway#GO:0001961;regulation of cellular response to stress#GO:0080135;cell activation involved in immune response#GO:0002263;regulation of response to cytokine stimulus#GO:0060759;lymphocyte activation involved in immune response#GO:0002285;T cell activation involved in immune response#GO:0002286;regulation of multicellular organismal process#GO:0051239;regulation of MAPK cascade#GO:0043408;immune effector process#GO:0002252;regulation of apoptotic process#GO:0042981;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 T cell activation#P00053>MHC-antigen#P01316 MONDO|Ensembl=ENSMODG00000006477.4|UniProtKB=A0A5F8GUV6 A0A5F8GUV6 VPS35L PTHR13673:SF0 ESOPHAGEAL CANCER ASSOCIATED PROTEIN VPS35 ENDOSOMAL PROTEIN-SORTING FACTOR-LIKE cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;intracellular transport#GO:0046907;transport#GO:0006810;localization within membrane#GO:0051668;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000006639.4|UniProtKB=F7G4B1 F7G4B1 MARCHF5 PTHR46283:SF4 E3 UBIQUITIN-PROTEIN LIGASE MARCH5 E3 UBIQUITIN-PROTEIN LIGASE MARCHF5 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 biological regulation#GO:0065007;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;regulation of anatomical structure morphogenesis#GO:0022603;metabolic process#GO:0008152;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of mitochondrial fission#GO:0090140;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;regulation of mitochondrion organization#GO:0010821;protein modification by small protein conjugation#GO:0032446;regulation of organelle organization#GO:0033043;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000006156.4|UniProtKB=F7BSK5 F7BSK5 NPHS2 PTHR10264:SF135 BAND 7 PROTEIN-RELATED PODOCIN channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;transporter regulator activity#GO:0141108 animal gross anatomical part developmental process#GO:0160108;renal system development#GO:0072001;developmental process#GO:0032502;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;system development#GO:0048731 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000016860.5|UniProtKB=F6QGI2 F6QGI2 CHRNA4 PTHR18945:SF401 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-4 molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic cation transmembrane transporter activity#GO:0008324;acetylcholine receptor activity#GO:0015464;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215 monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;neuromuscular synaptic transmission#GO:0007274;response to chemical#GO:0042221;regulation of trans-synaptic signaling#GO:0099177;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;synaptic signaling#GO:0099536;response to nitrogen compound#GO:1901698;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;trans-synaptic signaling#GO:0099537;membrane depolarization#GO:0051899;modulation of chemical synaptic transmission#GO:0050804;metal ion transport#GO:0030001;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;transport#GO:0006810;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500 synapse#GO:0045202;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;transporter complex#GO:1990351;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNA4#P06594;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088 MONDO|Ensembl=ENSMODG00000019239.4|UniProtKB=F6QU23 F6QU23 VMA12 PTHR31394:SF1 TRANSMEMBRANE PROTEIN 199 VACUOLAR ATPASE ASSEMBLY PROTEIN VMA12 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000023173.2|UniProtKB=F7D7P9 F7D7P9 PTHR23048:SF63 MYOSIN LIGHT CHAIN 1, 3 CALMODULIN-LIKE 5 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000009624.4|UniProtKB=F6REM2 F6REM2 NFE2L2 PTHR24411:SF3 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cellular response to oxidative stress#GO:0034599;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic leucine zipper transcription factor#PC00056 MONDO|Ensembl=ENSMODG00000020340.4|UniProtKB=F7FWK7 F7FWK7 NUP155 PTHR10350:SF6 NUCLEAR PORE COMPLEX PROTEIN NUP155 NUCLEAR PORE COMPLEX PROTEIN NUP155 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 establishment of RNA localization#GO:0051236;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;RNA transport#GO:0050658;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;nucleobase-containing compound transport#GO:0015931;nucleocytoplasmic transport#GO:0006913;localization within membrane#GO:0051668;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;localization#GO:0051179;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;chromosome organization#GO:0051276;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;protein transport#GO:0015031;protein import into nucleus#GO:0006606;cellular localization#GO:0051641;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;organelle organization#GO:0006996;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 MONDO|Ensembl=ENSMODG00000005907.4|UniProtKB=F6XD30 F6XD30 FFAR4 PTHR24241:SF67 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR FREE FATTY ACID RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000040315.1|UniProtKB=F6XXF7 F6XXF7 LOC100022429 PTHR26453:SF631 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038532.1|UniProtKB=A0A5F8HHL8 A0A5F8HHL8 LOC100618933 PTHR26450:SF424 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56A4 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003470.4|UniProtKB=A0A5F8HDU8 A0A5F8HDU8 ELL PTHR23288:SF9 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;snRNA metabolic process#GO:0016073;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of transcription elongation by RNA polymerase II#GO:0034243;nucleic acid biosynthetic process#GO:0141187;regulation of DNA-templated transcription elongation#GO:0032784;snRNA transcription#GO:0009301;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000020549.3|UniProtKB=F7AQE4 F7AQE4 UGDH PTHR11374:SF59 UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE UDP-GLUCOSE 6-DEHYDROGENASE carbohydrate derivative biosynthetic process#GO:1901137;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosaminoglycan metabolic process#GO:0030203;aminoglycan biosynthetic process#GO:0006023 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000001548.4|UniProtKB=F7EM19 F7EM19 PTHR21324:SF10 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED DNA DAMAGE-REGULATED AUTOPHAGY MODULATOR PROTEIN 2 retina homeostasis#GO:0001895;tissue homeostasis#GO:0001894;regulation of catabolic process#GO:0009894;multicellular organismal-level homeostasis#GO:0048871;regulation of autophagy#GO:0010506;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;homeostatic process#GO:0042592 lysosome#GO:0005764;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000060.4|UniProtKB=F6RDN7 F6RDN7 GYG2 PTHR11183:SF167 GLYCOGENIN SUBFAMILY MEMBER GLYCOGENIN-2 UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000002333.4|UniProtKB=A0A5F8GUX5 A0A5F8GUX5 ABHD6 PTHR43798:SF5 MONOACYLGLYCEROL LIPASE MONOACYLGLYCEROL LIPASE ABHD6 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;signaling receptor complex#GO:0043235 lipase#PC00143;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000003611.4|UniProtKB=F7C6I4 F7C6I4 PTHR23023:SF38 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000014783.4|UniProtKB=F7G6X0 F7G6X0 CUEDC1 PTHR13467:SF3 CUE DOMAIN CONTAINING PROTEIN 1 CUE DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000003945.4|UniProtKB=F7G9F9 F7G9F9 PCID2 PTHR12732:SF0 UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAINING PCI DOMAIN-CONTAINING PROTEIN 2 RNA binding#GO:0003723;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transport#GO:0006810;transcription by RNA polymerase II#GO:0006366;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;chromosome organization#GO:0051276;establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;establishment of RNA localization#GO:0051236;RNA biosynthetic process#GO:0032774;mRNA transport#GO:0051028;RNA localization#GO:0006403;RNA transport#GO:0050658;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;nucleobase-containing compound transport#GO:0015931;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;DNA-templated transcription elongation#GO:0006354;organelle organization#GO:0006996;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;nucleic acid biosynthetic process#GO:0141187;cellular localization#GO:0051641;RNA metabolic process#GO:0016070;mRNA export from nucleus#GO:0006406 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;transcription export complex 2#GO:0070390;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000045859.1|UniProtKB=A0A5F8GMH4 A0A5F8GMH4 C19orf25 PTHR34766:SF1 UPF0449 PROTEIN C19ORF25 UPF0449 PROTEIN C19ORF25 Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport#GO:0006810;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 MONDO|Ensembl=ENSMODG00000000562.4|UniProtKB=F6X4Z6 F6X4Z6 ARL8A PTHR45732:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8A vesicle-mediated transport#GO:0016192;cytoskeleton-dependent intracellular transport#GO:0030705;axo-dendritic transport#GO:0008088;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;microtubule-based movement#GO:0007018;cellular localization#GO:0051641;localization#GO:0051179;anterograde axonal transport#GO:0008089;axonal transport#GO:0098930;lysosomal transport#GO:0007041;microtubule-based transport#GO:0099111 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323 MONDO|Ensembl=ENSMODG00000010443.4|UniProtKB=A0A5F8H6Y5 A0A5F8H6Y5 PDE1A PTHR11347:SF34 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE DUAL SPECIFICITY CALCIUM_CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1A catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112 negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 cell body#GO:0044297;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphodiesterase#PC00185 CCKR signaling map#P06959>PDE#P07161 MONDO|Ensembl=ENSMODG00000022963.2|UniProtKB=F6WXR1 F6WXR1 PTHR11544:SF143 COLD SHOCK DOMAIN CONTAINING PROTEINS Y-BOX-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000013569.4|UniProtKB=A0A5F8GA33 A0A5F8GA33 TMPRSS13 PTHR24253:SF55 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 13 serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000018198.3|UniProtKB=F7B6U9 F7B6U9 ATF7IP PTHR23210:SF22 ACTIVATING TRANSCRIPTION FACTOR 7 INTERACTING PROTEIN ACTIVATING TRANSCRIPTION FACTOR 7-INTERACTING PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000016124.3|UniProtKB=F7DSS0 F7DSS0 LOC100023020 PTHR26453:SF265 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016301.4|UniProtKB=F7ATF2 F7ATF2 B4GALT5 PTHR19300:SF45 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 5 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000004900.3|UniProtKB=A0A5F8GZX7 A0A5F8GZX7 PTHR45831:SF3 LD24721P SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN ALPHA cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594 membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000025659.3|UniProtKB=F6XDP7 F6XDP7 PTHR47966:SF24 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED RENIN peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;peptide hormone processing#GO:0016486;blood circulation#GO:0008015;hormone metabolic process#GO:0042445;protein maturation#GO:0051604;gene expression#GO:0010467;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;system process#GO:0003008;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;proteolysis#GO:0006508;circulatory system process#GO:0003013;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;aspartic protease#PC00053 MONDO|Ensembl=ENSMODG00000003262.4|UniProtKB=K7E658 K7E658 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000014930.4|UniProtKB=F7FV77 F7FV77 PTHR46370:SF1 GPALPP MOTIFS-CONTAINING PROTEIN 1 GPALPP MOTIFS-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000008934.3|UniProtKB=K7E5Y2 K7E5Y2 PTHR28639:SF1 BCL-2-BINDING COMPONENT 3 BCL-2-BINDING COMPONENT 3, ISOFORMS 3_4 apoptotic signaling pathway#GO:0097190;biological regulation#GO:0065007;response to stress#GO:0006950;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of organelle organization#GO:0010638;intrinsic apoptotic signaling pathway#GO:0097193;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;regulation of release of cytochrome c from mitochondria#GO:0090199;positive regulation of cellular component organization#GO:0051130;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress#GO:0070059;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;programmed cell death#GO:0012501;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;execution phase of apoptosis#GO:0097194;regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000018960.4|UniProtKB=F7G0E0 F7G0E0 SEC24D PTHR13803:SF6 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24D SNARE binding#GO:0000149;zinc ion binding#GO:0008270;cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;cellular component organization#GO:0016043;COPII-coated vesicle budding#GO:0090114;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated membrane#GO:0048475;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;ER to Golgi transport vesicle membrane#GO:0012507;cytoplasm#GO:0005737;vesicle coat#GO:0030120;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506 vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000016355.4|UniProtKB=F7F766 F7F766 NMRAL1 PTHR42748:SF16 NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER NMRA-LIKE FAMILY DOMAIN-CONTAINING PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000003652.4|UniProtKB=A0A5F8GXA7 A0A5F8GXA7 PTHR10903:SF7 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 2 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000008447.3|UniProtKB=F7GF12 F7GF12 PTHR46754:SF1 MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 MONDO|Ensembl=ENSMODG00000038496.1|UniProtKB=A0A5F8H982 A0A5F8H982 PTHR24381:SF435 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 275 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017232.4|UniProtKB=F6WHS7 F6WHS7 PIR PTHR13903:SF33 PIRIN-RELATED PIRIN dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;transcription regulator activity#GO:0140110 developmental process#GO:0032502;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;leukocyte differentiation#GO:0002521;mononuclear cell differentiation#GO:1903131;cellular process#GO:0009987;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;cell development#GO:0048468;hemopoiesis#GO:0030097 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000001909.4|UniProtKB=F6W1E6 F6W1E6 TCP11L2 PTHR12832:SF17 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 T-COMPLEX PROTEIN 11-LIKE PROTEIN 2 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000018265.3|UniProtKB=F6Q7S7 F6Q7S7 GALNT8 PTHR11675:SF50 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 8-RELATED polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000042582.1|UniProtKB=A0A5F8GN18 A0A5F8GN18 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000000021.2|UniProtKB=F6SIE4 F6SIE4 PTHR45715:SF23 ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED ATPASE H+ TRANSPORTING V1 SUBUNIT E1 monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;organelle#GO:0043226;cellular anatomical structure#GO:0110165;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000017989.4|UniProtKB=F7B8K0 F7B8K0 CEP57L1 PTHR19336:SF10 UNCHARACTERIZED DUF1167 CENTROSOMAL PROTEIN CEP57L1 molecular adaptor activity#GO:0060090;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;cytoskeletal adaptor activity#GO:0008093;protein binding#GO:0005515;protein-macromolecule adaptor activity#GO:0030674;microtubule binding#GO:0008017;binding#GO:0005488 chromosome localization#GO:0050000;cytoskeleton organization#GO:0007010;attachment of spindle microtubules to kinetochore#GO:0008608;organelle organization#GO:0006996;cellular process#GO:0009987;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;nuclear chromosome segregation#GO:0098813;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;organelle localization#GO:0051640 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000015412.4|UniProtKB=F6T3K4 F6T3K4 LOC100017350 PTHR11006:SF49 PROTEIN ARGININE N-METHYLTRANSFERASE HISTONE-ARGININE METHYLTRANSFERASE CARM1 ISOFORM X1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000009632.3|UniProtKB=F6RDR6 F6RDR6 LCTL PTHR10353:SF336 GLYCOSYL HYDROLASE LACTASE-LIKE PROTEIN hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;glucosidase activity#GO:0015926;beta-glucosidase activity#GO:0008422;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 glycosidase#PC00110;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000011370.4|UniProtKB=F6SPN8 F6SPN8 GBF1 PTHR10663:SF412 GUANYL-NUCLEOTIDE EXCHANGE FACTOR GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;cellular process#GO:0009987;Golgi organization#GO:0007030;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus subcompartment#GO:0098791;Golgi stack#GO:0005795;organelle#GO:0043226;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;Golgi cis cisterna#GO:0000137;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000015019.4|UniProtKB=H9H6R3 H9H6R3 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of biological process#GO:0050789;signal transduction#GO:0007165;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000013993.4|UniProtKB=F6QKC1 F6QKC1 IP6K3 PTHR12400:SF40 INOSITOL POLYPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE KINASE 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776 glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase#PC00137 MONDO|Ensembl=ENSMODG00000049758.1|UniProtKB=A0A5F8GGT3 A0A5F8GGT3 PTHR23299:SF24 METALLOTHIONEIN METALLOTHIONEIN-1E-RELATED defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000027435.2|UniProtKB=K7DZF5 K7DZF5 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002641.4|UniProtKB=F7DIF8 F7DIF8 GDA PTHR11271:SF6 GUANINE DEAMINASE GUANINE DEAMINASE cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;zinc ion binding#GO:0008270 nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;purine nucleobase catabolic process#GO:0006145;purine-containing compound catabolic process#GO:0072523;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 deaminase#PC00088 Purine metabolism#P02769>Guanine Deaminase#P03118;Xanthine and guanine salvage pathway#P02788>Guanine deaminase#P03249 MONDO|Ensembl=ENSMODG00000012815.4|UniProtKB=F7DY38 F7DY38 LOC100010167 PTHR11662:SF459 SOLUTE CARRIER FAMILY 17 SIALIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000037806.1|UniProtKB=A0A5F8GWC3 A0A5F8GWC3 PTHR12297:SF5 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1A, MITOCHONDRIAL regulation of cellular process#GO:0050794;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;negative regulation of apoptotic process#GO:0043066;cellular component assembly#GO:0022607;biological regulation#GO:0065007;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000023970.3|UniProtKB=F7DA39 F7DA39 PTHR26450:SF411 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51A7 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014063.4|UniProtKB=F7EIJ8 F7EIJ8 PTHR45638:SF16 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL BETA-1 ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;gated channel activity#GO:0022836;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;heterocyclic compound binding#GO:1901363 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;retina homeostasis#GO:0001895;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;multicellular organismal-level homeostasis#GO:0048871;tissue homeostasis#GO:0001894;transport#GO:0006810;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;homeostatic process#GO:0042592;cellular process#GO:0009987 cilium#GO:0005929;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;membrane protein complex#GO:0098796;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cation channel complex#GO:0034703;transporter complex#GO:1990351;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886 ion channel#PC00133;ligand-gated ion channel#PC00141 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 MONDO|Ensembl=ENSMODG00000001127.4|UniProtKB=A0A5F8G5X1 A0A5F8G5X1 TRIM2 PTHR24104:SF58 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 2 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>HAC1#P00131 MONDO|Ensembl=ENSMODG00000008706.4|UniProtKB=F6PWG0 F6PWG0 PRKCH PTHR24356:SF192 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C ETA TYPE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 non-receptor serine/threonine protein kinase#PC00167 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;CCKR signaling map#P06959>PKCeta#P07068;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;FGF signaling pathway#P00021>PKC#P00648;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Endothelin signaling pathway#P00019>PKC#P00568;Angiogenesis#P00005>PKC#P00219;VEGF signaling pathway#P00056>PKC#P01425;EGF receptor signaling pathway#P00018>PKC#P00565;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;Apoptosis signaling pathway#P00006>PKCs#P00318 MONDO|Ensembl=ENSMODG00000015670.3|UniProtKB=F7EI48 F7EI48 MAPK3 PTHR24055:SF393 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>MAPK3#P07119;CCKR signaling map#P06959>MAPK1/3#P07228;Ras Pathway#P04393>ERK#P04542;T cell activation#P00053>ERK#P01300;PDGF signaling pathway#P00047>ERK#P01143;Angiogenesis#P00005>MEK#P00225;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;Endothelin signaling pathway#P00019>ERK#P00566;Apoptosis signaling pathway#P00006>MAPK#P00269;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Parkinson disease#P00049>ERK#P01211;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;VEGF signaling pathway#P00056>Erk#P01407;Gonadotropin-releasing hormone receptor pathway#P06664>ERK1/2#P06786;EGF receptor signaling pathway#P00018>ERK1-2#P00543;Toll receptor signaling pathway#P00054>ERK1#P01358;Angiogenesis#P00005>Erk#P00203;FGF signaling pathway#P00021>ERK1-2#P00627;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;VEGF signaling pathway#P00056>MEK#P01402;B cell activation#P00010>ERK#P00371;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>MAPK#P05937;Integrin signalling pathway#P00034>ERK#P00907;Interleukin signaling pathway#P00036>ERK#P00965;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835 MONDO|Ensembl=ENSMODG00000014418.4|UniProtKB=A0A5F8H2B8 A0A5F8H2B8 PTHR11627:SF2 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE B carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;fructose-bisphosphate aldolase activity#GO:0004332;aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829 pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523;ADP catabolic process#GO:0046032;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 aldolase#PC00044;lyase#PC00144 Glycolysis#P00024>Aldolase#P00679;Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959 MONDO|Ensembl=ENSMODG00000004063.4|UniProtKB=A0A5F8HJ50 A0A5F8HJ50 ZNF618 PTHR24383:SF12 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 618 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015592.3|UniProtKB=F6ZUF6 F6ZUF6 GPN1 PTHR21231:SF8 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 G-protein#PC00020;protein-binding activity modulator#PC00095;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000046577.1|UniProtKB=A0A5F8GH37 A0A5F8GH37 VN2R632 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000039986.1|UniProtKB=A0A5F8GDV2 A0A5F8GDV2 PTHR26453:SF115 OLFACTORY RECEPTOR OLFACTORY RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000039216.1|UniProtKB=A0A5F8G3T1 A0A5F8G3T1 URAD PTHR43466:SF1 2-OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE-RELATED 2-OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE lyase activity#GO:0016829;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262;lyase#PC00144 MONDO|Ensembl=ENSMODG00000012559.4|UniProtKB=F6QLD2 F6QLD2 GTF3C4 PTHR15496:SF2 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 FAMILY GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000009966.4|UniProtKB=F6Y7W9 F6Y7W9 ARIH1 PTHR11685:SF475 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ARIH1 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000018677.4|UniProtKB=F7AEQ7 F7AEQ7 PTHR13140:SF505 MYOSIN UNCONVENTIONAL MYOSIN-VIIB ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 system process#GO:0003008;actin filament organization#GO:0007015;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;sensory organ development#GO:0007423;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin filament-based movement#GO:0030048;cellular process#GO:0009987;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;nervous system process#GO:0050877;actin filament-based process#GO:0030029;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;actin cytoskeleton organization#GO:0030036;sensory perception of sound#GO:0007605;cellular component organization#GO:0016043 membrane#GO:0016020;brush border#GO:0005903;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;microvillus#GO:0005902;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000008187.5|UniProtKB=A0A5F8GQF8 A0A5F8GQF8 MCM3AP PTHR12436:SF39 80 KDA MCM3-ASSOCIATED PROTEIN GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;transcription export complex 2#GO:0070390;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007354.4|UniProtKB=F7ADS9 F7ADS9 POLA1 PTHR45861:SF1 DNA POLYMERASE ALPHA CATALYTIC SUBUNIT DNA POLYMERASE ALPHA CATALYTIC SUBUNIT DNA-directed DNA polymerase activity#GO:0003887;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;single-stranded DNA binding#GO:0003697;binding#GO:0005488;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;transferase activity#GO:0016740 DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;replisome#GO:0030894;nuclear DNA-directed RNA polymerase complex#GO:0055029;replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 DNA replication#P00017>Pol alpha#P00531 MONDO|Ensembl=ENSMODG00000045976.1|UniProtKB=A0A5F8GTG6 A0A5F8GTG6 LOC103093760 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002467.4|UniProtKB=F7DDQ8 F7DDQ8 ILDR2 PTHR15923:SF0 TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING RECEPTOR 2 developmental process#GO:0032502;pancreas development#GO:0031016;animal gross anatomical part developmental process#GO:0160108;animal organ development#GO:0048513;anatomical structure development#GO:0048856 membrane#GO:0016020;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000021201.4|UniProtKB=A0A5F8HDU4 A0A5F8HDU4 SERPINE2 PTHR11461:SF48 SERINE PROTEASE INHIBITOR, SERPIN GLIA-DERIVED NEXIN endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134 negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000025754.2|UniProtKB=A0A5F8G5J1 A0A5F8G5J1 PTHR23299:SF24 METALLOTHIONEIN METALLOTHIONEIN-1E-RELATED defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000000183.4|UniProtKB=F6TG00 F6TG00 LBP PTHR10504:SF66 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED LIPOPOLYSACCHARIDE-BINDING PROTEIN lipopolysaccharide binding#GO:0001530;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;lipid binding#GO:0008289 regulation of leukocyte activation#GO:0002694;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;defense response to Gram-negative bacterium#GO:0050829;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;defense response to bacterium#GO:0042742;cell activation involved in immune response#GO:0002263;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;regulation of macrophage activation#GO:0043030;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;defense response to other organism#GO:0098542;response to chemical#GO:0042221;myeloid leukocyte activation#GO:0002274;regulation of multicellular organismal process#GO:0051239;leukocyte activation involved in immune response#GO:0002366;positive regulation of leukocyte activation#GO:0002696;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;response to lipopolysaccharide#GO:0032496;cellular response to biotic stimulus#GO:0071216;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;lipopolysaccharide-mediated signaling pathway#GO:0031663;response to bacterium#GO:0009617;cell activation#GO:0001775;inflammatory response#GO:0006954;cell communication#GO:0007154;acute inflammatory response#GO:0002526;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;multicellular organismal process#GO:0032501;response to other organism#GO:0051707;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;cellular response to molecule of bacterial origin#GO:0071219;macrophage activation#GO:0042116;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000006031.4|UniProtKB=F6ZV15 F6ZV15 INSM1 PTHR15065:SF5 INSULINOMA-ASSOCIATED 1 INSULINOMA-ASSOCIATED PROTEIN 1 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of cell cycle process#GO:0010564;nervous system development#GO:0007399;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605 intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000004591.2|UniProtKB=F6QIS8 F6QIS8 COX4I1 PTHR10707:SF12 CYTOCHROME C OXIDASE SUBUNIT IV CYTOCHROME C OXIDASE SUBUNIT 4 ISOFORM 1, MITOCHONDRIAL generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transporter complex#GO:1990351;organelle membrane#GO:0031090 oxidoreductase#PC00176;oxidase#PC00175 MONDO|Ensembl=ENSMODG00000007203.4|UniProtKB=F6WTX7 F6WTX7 ASB12 PTHR24120:SF8 GH07239P ANKYRIN REPEAT AND SOCS BOX PROTEIN 12 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 MONDO|Ensembl=ENSMODG00000011969.4|UniProtKB=F7BA23 F7BA23 SGCA PTHR10132:SF16 ALPHA-/EPSILON-SARCOGLYCAN FAMILY MEMBER ALPHA-SARCOGLYCAN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796 cadherin#PC00057 MONDO|Ensembl=ENSMODG00000051141.1|UniProtKB=A0A5F8G2U9 A0A5F8G2U9 LOC100031185 PTHR26454:SF77 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018300.2|UniProtKB=A0A5F8H877 A0A5F8H877 FAM162A PTHR13674:SF2 GROWTH AND TRANSFORMATION-DEPENDENT PROTEIN PROTEIN FAM162A response to hypoxia#GO:0001666;response to stress#GO:0006950;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of release of cytochrome c from mitochondria#GO:0090199;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;neuron apoptotic process#GO:0051402;cellular response to hypoxia#GO:0071456;programmed cell death#GO:0012501;response to abiotic stimulus#GO:0009628;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000023866.3|UniProtKB=M9MMH6 M9MMH6 PTHR44427:SF13 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 4-RELATED cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000046314.1|UniProtKB=A0A5F8GAJ7 A0A5F8GAJ7 PTHR21377:SF0 PROTEIN FAM210B, MITOCHONDRIAL PROTEIN FAM210B, MITOCHONDRIAL intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000013855.4|UniProtKB=F7AYB5 F7AYB5 ANKS1A PTHR24174:SF4 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 1A binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;ephrin receptor signaling pathway#GO:0048013;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019251.3|UniProtKB=F6QSP6 F6QSP6 FOXN1 PTHR46721:SF1 FORKHEAD BOX PROTEIN N1 FORKHEAD BOX PROTEIN N1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000019149.3|UniProtKB=F7EC67 F7EC67 NCLN PTHR31826:SF8 NICALIN BOS COMPLEX SUBUNIT NCLN regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000040763.1|UniProtKB=A0A5F8GJR3 A0A5F8GJR3 LOC103102315 PTHR24242:SF197 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000220.4|UniProtKB=A0A5F8GCP4 A0A5F8GCP4 PPP3CB PTHR45673:SF7 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT BETA ISOFORM phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;calmodulin binding#GO:0005516;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;binding#GO:0005488;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;protein binding#GO:0005515;hydrolase activity#GO:0016787 calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;calcineurin-mediated signaling#GO:0097720 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287 protein phosphatase#PC00195 Wnt signaling pathway#P00057>Calcineurin#P01446;T cell activation#P00053>Calcineurin#P01315;B cell activation#P00010>Calcineurin#P00386 MONDO|Ensembl=ENSMODG00000014729.4|UniProtKB=F6ZCR9 F6ZCR9 AASDHPPT PTHR12215:SF10 PHOSPHOPANTETHEINE TRANSFERASE L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000040850.1|UniProtKB=A0A5F8GVQ9 A0A5F8GVQ9 PTHR40389:SF3 ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED IGE-BINDING PROTEIN MONDO|Ensembl=ENSMODG00000042017.1|UniProtKB=A0A5F8HGX5 A0A5F8HGX5 LOC100617077 PTHR26450:SF138 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009102.4|UniProtKB=F7FCH6 F7FCH6 SCRIB PTHR23119:SF57 DISCS LARGE PROTEIN SCRIBBLE HOMOLOG molecular adaptor activity#GO:0060090;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591;protein binding#GO:0005515 intracellular protein transport#GO:0006886;protein localization to cell periphery#GO:1990778;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;endosomal transport#GO:0016197;protein localization to synapse#GO:0035418;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cell-cell adhesion#GO:0098609;establishment of protein localization to membrane#GO:0090150;vesicle-mediated transport#GO:0016192;cell adhesion#GO:0007155;receptor clustering#GO:0043113;establishment or maintenance of cell polarity#GO:0007163;protein transport#GO:0015031;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;protein localization to membrane#GO:0072657;endocytic recycling#GO:0032456;transport#GO:0006810;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;endosome to plasma membrane protein transport#GO:0099638;macromolecule localization#GO:0033036;biological regulation#GO:0065007;cell migration#GO:0016477;establishment or maintenance of bipolar cell polarity#GO:0061245;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;establishment or maintenance of apical/basal cell polarity#GO:0035088;protein localization to cell junction#GO:1902414;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;cell motility#GO:0048870 adherens junction#GO:0005912;cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;basal part of cell#GO:0045178;postsynapse#GO:0098794 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000039411.1|UniProtKB=A0A5F8GAV1 A0A5F8GAV1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009654.4|UniProtKB=F6Q8B1 F6Q8B1 DCN PTHR45712:SF14 AGAP008170-PA DECORIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000016075.4|UniProtKB=F7G9S0 F7G9S0 BOK PTHR11256:SF48 BCL-2 RELATED BCL-2-RELATED OVARIAN KILLER PROTEIN channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cellular process#GO:0050794;cell death#GO:0008219;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;organelle organization#GO:0006996;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;signaling#GO:0023052;release of cytochrome c from mitochondria#GO:0001836;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519 mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 Apoptosis signaling pathway#P00006>Bok#P00261 MONDO|Ensembl=ENSMODG00000024772.2|UniProtKB=F7CQU9 F7CQU9 B3GNT5 PTHR11214:SF21 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE LACTOSYLCERAMIDE 1,3-N-ACETYL-BETA-D-GLUCOSAMINYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000019575.4|UniProtKB=F7EZ04 F7EZ04 PTHR24543:SF317 MULTICOPPER OXIDASE-RELATED LACTADHERIN phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;phospholipid binding#GO:0005543;ion binding#GO:0043167 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000046429.1|UniProtKB=A0A5F8G221 A0A5F8G221 PTHR14225:SF0 APOLIPOPROTEIN C-III APOLIPOPROTEIN C-III signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;lipid binding#GO:0008289;lipoprotein particle receptor binding#GO:0070325;phospholipid binding#GO:0005543;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772 primary metabolic process#GO:0044238;negative regulation of multicellular organismal process#GO:0051241;regulation of lipid catabolic process#GO:0050994;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;homeostatic process#GO:0042592;regulation of lipid metabolic process#GO:0019216;triglyceride homeostasis#GO:0070328;negative regulation of catabolic process#GO:0009895;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;acylglycerol metabolic process#GO:0006639;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid catabolic process#GO:0046461;cholesterol homeostasis#GO:0042632;neutral lipid metabolic process#GO:0006638;regulation of catabolic process#GO:0009894;lipid homeostasis#GO:0055088;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;negative regulation of metabolic process#GO:0009892;glycerolipid catabolic process#GO:0046503;triglyceride catabolic process#GO:0019433;cellular process#GO:0009987;lipid catabolic process#GO:0016042;regulation of multicellular organismal process#GO:0051239;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;acylglycerol catabolic process#GO:0046464 high-density lipoprotein particle#GO:0034364;plasma lipoprotein particle#GO:0034358;lipoprotein particle#GO:1990777;extracellular protein-containing complex#GO:0140392;protein-lipid complex#GO:0032994;extracellular region#GO:0005576;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;very-low-density lipoprotein particle#GO:0034361 transfer/carrier protein#PC00219;apolipoprotein#PC00052 MONDO|Ensembl=ENSMODG00000014519.4|UniProtKB=F7ERP5 F7ERP5 ILVBL PTHR18968:SF166 THIAMINE PYROPHOSPHATE ENZYMES 2-HYDROXYACYL-COA LYASE 2 nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;transketolase or transaldolase activity#GO:0016744;catalytic activity#GO:0003824;transferase activity#GO:0016740;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;proteinogenic amino acid biosynthetic process#GO:0170038;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;branched-chain amino acid biosynthetic process#GO:0009082;small molecule biosynthetic process#GO:0044283 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;ligase#PC00142 Valine biosynthesis#P02785>Acetolactate synthase#P03216;Isoleucine biosynthesis#P02748>Acetolactate synthase#P02997 MONDO|Ensembl=ENSMODG00000040618.1|UniProtKB=A0A5F8HFQ7 A0A5F8HFQ7 TMOD2 PTHR10901:SF18 TROPOMODULIN TROPOMODULIN-3 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;developmental process#GO:0032502;muscle contraction#GO:0006936;actin filament organization#GO:0007015;system process#GO:0003008;cellular developmental process#GO:0048869;multicellular organismal process#GO:0032501 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;contractile muscle fiber#GO:0043292;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000018832.3|UniProtKB=F7GKC0 F7GKC0 PTHR16240:SF2 PROTEIN MENT PROTEIN MENT MONDO|Ensembl=ENSMODG00000008056.4|UniProtKB=F6Z9I7 F6Z9I7 PTHR23147:SF80 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN 4B circadian rhythm#GO:0007623;rhythmic process#GO:0048511 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;membraneless organelle#GO:0043228;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000041343.1|UniProtKB=A0A5F8GEH3 A0A5F8GEH3 PTHR24390:SF250 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 763 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000007056.4|UniProtKB=A0A5F8GNW2 A0A5F8GNW2 PTHR31606:SF2 WW DOMAIN BINDING PROTEIN 2, ISOFORM E POSTACROSOMAL SHEATH WW DOMAIN-BINDING PROTEIN chromatin DNA binding#GO:0031490;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000037484.1|UniProtKB=A0A5F8GLZ8 A0A5F8GLZ8 LOC100620040 PTHR35349:SF4 DYNACTIN-ASSOCIATED PROTEIN CUPIN SUPERFAMILY MEMBER 1A-RELATED microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000047345.1|UniProtKB=K7DYY1 K7DYY1 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000020074.2|UniProtKB=F7GIC6 F7GIC6 LOC100024976 PTHR26452:SF292 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5G3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010537.3|UniProtKB=F6ZF19 F6ZF19 SMYD4 PTHR46165:SF2 SET AND MYND DOMAIN-CONTAINING PROTEIN 4 PROTEIN-LYSINE N-METHYLTRANSFERASE SMYD4 histone deacetylase binding#GO:0042826;protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 heart development#GO:0007507;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501;system development#GO:0048731;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000051523.1|UniProtKB=A0A5F8GCP2 A0A5F8GCP2 NCMAP PTHR35974:SF1 NONCOMPACT MYELIN-ASSOCIATED PROTEIN NONCOMPACT MYELIN-ASSOCIATED PROTEIN structural molecule activity#GO:0005198 gliogenesis#GO:0042063;myelination#GO:0042552;neurogenesis#GO:0022008;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;nervous system development#GO:0007399;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;system development#GO:0048731;anatomical structure development#GO:0048856;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;peripheral nervous system development#GO:0007422;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;myelin sheath#GO:0043209;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;main axon#GO:0044304;axon#GO:0030424 myelin protein#PC00161;structural protein#PC00211 MONDO|Ensembl=ENSMODG00000003210.4|UniProtKB=F6TZJ8 F6TZJ8 XPA PTHR10142:SF0 DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;damaged DNA binding#GO:0003684 cellular response to stress#GO:0033554;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to abiotic stimulus#GO:0009628;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;cellular response to environmental stimulus#GO:0104004;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to radiation#GO:0071478;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;response to UV#GO:0009411;cellular response to abiotic stimulus#GO:0071214;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;response to radiation#GO:0009314;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleotide-excision repair complex#GO:0000109;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000028653.2|UniProtKB=A0A5F8HCF3 A0A5F8HCF3 LOC100025102 PTHR11461:SF204 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B6 peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000008263.3|UniProtKB=A0A5F8GN02 A0A5F8GN02 PLEKHA1 PTHR14336:SF4 TANDEM PH DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 1 lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;phospholipid binding#GO:0005543;binding#GO:0005488 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000014189.1|UniProtKB=F6U6M6 F6U6M6 SH3BGRL3 PTHR12232:SF3 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN 3 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000006407.4|UniProtKB=F6TT20 F6TT20 ZDHHC12 PTHR22883:SF514 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC12 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting#GO:0006605;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000020067.2|UniProtKB=F7GIK0 F7GIK0 LOC100024645 PTHR48018:SF129 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 9G4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000046621.1|UniProtKB=A0A5F8H1L6 A0A5F8H1L6 monDomV1R1202 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023719.2|UniProtKB=A0A5F8GN93 A0A5F8GN93 CMKLR1 PTHR24225:SF49 CHEMOTACTIC RECEPTOR CHEMERIN-LIKE RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;regulation of cell migration#GO:0030334;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;locomotion#GO:0040011;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of leukocyte migration#GO:0002685;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;cell communication#GO:0007154;positive regulation of chemotaxis#GO:0050921;regulation of immune response#GO:0050776;chemotaxis#GO:0006935;regulation of granulocyte chemotaxis#GO:0071622;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to chemical#GO:0042221;taxis#GO:0042330;regulation of response to external stimulus#GO:0032101;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;positive regulation of cell motility#GO:2000147;regulation of chemotaxis#GO:0050920;regulation of biological quality#GO:0065008;regulation of signaling#GO:0023051;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of intracellular signal transduction#GO:1902531 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000045810.1|UniProtKB=A0A5F8H2Z8 A0A5F8H2Z8 ABRA PTHR22739:SF20 STRIATED MUSCLE ACTIVATOR OF RHO-DEPENDENT SIGNALING-RELATED ACTIN-BINDING RHO-ACTIVATING PROTEIN positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of Rho protein signal transduction#GO:0035023;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of RNA biosynthetic process#GO:1902680;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;positive regulation of signal transduction#GO:0009967;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;contractile muscle fiber#GO:0043292 MONDO|Ensembl=ENSMODG00000001084.4|UniProtKB=F7GHR5 F7GHR5 UAP1 PTHR11952:SF4 UDP- GLUCOSE PYROPHOSPHORYLASE UDP-N-ACETYLHEXOSAMINE PYROPHOSPHORYLASE transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;UDP-N-acetylglucosamine biosynthetic process#GO:0006048;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine metabolic process#GO:0006047;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-sugar metabolic process#GO:0009225;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000012675.4|UniProtKB=F6VGX5 F6VGX5 URI1 PTHR15111:SF2 RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3 UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1 chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;binding#GO:0005488;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208 regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of signal transduction#GO:0009968;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of programmed cell death#GO:0043069;negative regulation of RNA metabolic process#GO:0051253;regulation of apoptotic process#GO:0042981;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000007211.3|UniProtKB=F6WT87 F6WT87 PTHR22237:SF0 APC MEMBRANE RECRUITMENT PROTEIN 2-RELATED APC MEMBRANE RECRUITMENT PROTEIN 1 protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000046131.1|UniProtKB=A0A5F8G2A8 A0A5F8G2A8 VWC2 PTHR46252:SF4 BRORIN FAMILY MEMBER BRORIN regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of BMP signaling pathway#GO:0030510;negative regulation of BMP signaling pathway#GO:0030514;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;extracellular region#GO:0005576;signaling receptor complex#GO:0043235;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 MONDO|Ensembl=ENSMODG00000044376.1|UniProtKB=A0A5F8HI88 A0A5F8HI88 PTHR15478:SF4 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, PQ-RICH PROTEIN PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY A MEMBER 1 biological regulation#GO:0065007;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000020685.4|UniProtKB=F7DKS7 F7DKS7 DDIT4L PTHR12478:SF17 DNA-DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN DDIT4 DNA DAMAGE-INDUCIBLE TRANSCRIPT 4-LIKE PROTEIN regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of biological process#GO:0050789;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 MONDO|Ensembl=ENSMODG00000012494.4|UniProtKB=F7D1B8 F7D1B8 MSN PTHR23281:SF26 MERLIN/MOESIN/EZRIN/RADIXIN MOESIN binding#GO:0005488;cell adhesion molecule binding#GO:0050839;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 regulation of anatomical structure morphogenesis#GO:0022603;regulation of localization#GO:0032879;regulation of transport#GO:0051049;biological regulation#GO:0065007;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360 intracellular organelle#GO:0043229;filopodium#GO:0030175;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;actin-based cell projection#GO:0098858;microvillus#GO:0005902;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;adherens junction#GO:0005912;membraneless organelle#GO:0043228;cell junction#GO:0030054;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000006043.4|UniProtKB=F6Z624 F6Z624 PTHR24376:SF38 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 544-RELATED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000047512.1|UniProtKB=A0A5F8HIT3 A0A5F8HIT3 PTHR24390:SF290 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 184 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004431.3|UniProtKB=A0A5F8GAB8 A0A5F8GAB8 ACVR1 PTHR23255:SF69 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-1 kinase activity#GO:0016301;transforming growth factor beta receptor activity#GO:0005024;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;molecular transducer activity#GO:0060089 animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;signaling#GO:0023052;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;animal organ development#GO:0048513;transforming growth factor beta receptor signaling pathway#GO:0007179;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;pattern specification process#GO:0007389;response to transforming growth factor beta#GO:0071559;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;dorsal/ventral pattern formation#GO:0009953;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;response to BMP#GO:0071772;cellular developmental process#GO:0048869;multicellular organismal process#GO:0032501;regionalization#GO:0003002;biological regulation#GO:0065007 signaling receptor complex#GO:0043235;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283 MONDO|Ensembl=ENSMODG00000042569.1|UniProtKB=A0A5F8GK22 A0A5F8GK22 LOC100019935 PTHR10029:SF20 ACYLPHOSPHATASE ACYLPHOSPHATASE-2 pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000028196.2|UniProtKB=K7E1P4 K7E1P4 LOC103103995 PTHR12002:SF108 CLAUDIN CLAUDIN cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987 anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;apical junction complex#GO:0043296;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000007125.4|UniProtKB=F6SH72 F6SH72 APEX1 PTHR22748:SF6 AP ENDONUCLEASE DNA REPAIR NUCLEASE_REDOX REGULATOR APEX1 3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;DNA exonuclease activity#GO:0004529;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;DNA endonuclease activity#GO:0004520;exonuclease activity#GO:0004527;endonuclease activity#GO:0004519;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000006099.4|UniProtKB=F7F104 F7F104 SYT9 PTHR10024:SF180 SYNAPTOTAGMIN SYNAPTOTAGMIN-9 molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;protein binding#GO:0005515;phospholipid binding#GO:0005543;binding#GO:0005488;SNARE binding#GO:0000149 positive regulation of organelle organization#GO:0010638;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;trans-synaptic signaling#GO:0099537;positive regulation of cellular component organization#GO:0051130;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;establishment of localization#GO:0051234;regulation of localization#GO:0032879;positive regulation of vesicle fusion#GO:0031340;regulation of transport#GO:0051049;transport#GO:0006810;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000009834.4|UniProtKB=F6WB19 F6WB19 ADRB1 PTHR24248:SF54 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR BETA-1 ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;blood circulation#GO:0008015;biological regulation#GO:0065007;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of anatomical structure size#GO:0090066;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;vasodilation#GO:0042311;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of biological quality#GO:0065008;adrenergic receptor signaling pathway#GO:0071875;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Beta1 adrenergic receptor signaling pathway#P04377>Beta1#P04433 MONDO|Ensembl=ENSMODG00000009573.3|UniProtKB=F7AX42 F7AX42 NPBWR1 PTHR24229:SF47 NEUROPEPTIDES RECEPTOR NEUROPEPTIDES B_W RECEPTOR TYPE 1 transmembrane signaling receptor activity#GO:0004888;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;binding#GO:0005488;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000001267.3|UniProtKB=F7CIX7 F7CIX7 FSHR PTHR24372:SF5 GLYCOPROTEIN HORMONE RECEPTOR FOLLICLE-STIMULATING HORMONE RECEPTOR G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 developmental process#GO:0032502;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;male sex differentiation#GO:0046661;development of primary male sexual characteristics#GO:0046546;biological regulation#GO:0065007;gonad development#GO:0008406;multicellular organismal process#GO:0032501;system development#GO:0048731;female gonad development#GO:0008585;multicellular organismal reproductive process#GO:0048609;reproductive system development#GO:0061458;cell communication#GO:0007154;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;development of primary sexual characteristics#GO:0045137;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;multicellular organism development#GO:0007275;animal organ development#GO:0048513;male gonad development#GO:0008584;signal transduction#GO:0007165;sex differentiation#GO:0007548;cellular process#GO:0009987;response to hormone#GO:0009725;response to chemical#GO:0042221;rhythmic process#GO:0048511;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;reproductive structure development#GO:0048608;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000002082.3|UniProtKB=F6UZH1 F6UZH1 TFG PTHR15335:SF7 PROTEIN TFG PROTEIN TFG establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000001998.3|UniProtKB=F6RHS1 F6RHS1 PTHR15336:SF0 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex III#GO:0045275;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;reductase#PC00198 MONDO|Ensembl=ENSMODG00000050827.1|UniProtKB=A0A5F8H9S7 A0A5F8H9S7 JAML PTHR13869:SF22 MYELIN P0 RELATED JUNCTIONAL ADHESION MOLECULE-LIKE cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 myelin protein#PC00161 MONDO|Ensembl=ENSMODG00000048370.1|UniProtKB=A0A5F8HJS2 A0A5F8HJS2 PTHR28342:SF1 MONOOXYGENASE P33MONOX-RELATED MONOOXYGENASE P33MONOX-RELATED intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000016134.3|UniProtKB=F7DS01 F7DS01 MRPS34 PTHR28589:SF1 28S RIBOSOMAL PROTEIN S34, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN MS34 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000007865.4|UniProtKB=F7EBE9 F7EBE9 CCL21 PTHR12015:SF72 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 21 molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 response to peptide#GO:1901652;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to cytokine#GO:0034097;taxis#GO:0042330;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;response to stress#GO:0006950;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;regulation of cell motility#GO:2000145;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326;cytokine-mediated signaling pathway#GO:0019221;inflammatory response#GO:0006954;chemotaxis#GO:0006935;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;cellular response to chemokine#GO:1990869;cellular response to stimulus#GO:0051716;myeloid leukocyte migration#GO:0097529;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;cell migration#GO:0016477;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000005287.4|UniProtKB=F7E6T2 F7E6T2 SPTLC2 PTHR13693:SF79 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingoid biosynthetic process#GO:0046520;ceramide metabolic process#GO:0006672;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991 transaminase#PC00216 MONDO|Ensembl=ENSMODG00000015992.3|UniProtKB=F7EZA3 F7EZA3 NUGGC PTHR47308:SF1 NUCLEAR GTPASE SLIP-GC NUCLEAR GTPASE SLIP-GC hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 MONDO|Ensembl=ENSMODG00000011882.3|UniProtKB=A0A5F8HAT8 A0A5F8HAT8 GMCL1 PTHR23231:SF17 GERM CELL-LESS PROTEIN GERM CELL-LESS 1, SPERMATOSIS ASSOCIATED ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000007652.4|UniProtKB=F7FZG4 F7FZG4 PDZD9 PTHR22698:SF1 PDZ DOMAIN-CONTAINING PROTEIN 9 PDZ DOMAIN-CONTAINING PROTEIN 9 MONDO|Ensembl=ENSMODG00000011663.4|UniProtKB=F6YEC5 F6YEC5 LOC100022920 PTHR12570:SF10 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED MGC108429 PROTEIN metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;magnesium ion transport#GO:0015693 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000008021.4|UniProtKB=F7CL00 F7CL00 BAMBI PTHR15505:SF1 RIIA DOMAIN-CONTAINING PROTEIN 1 BMP AND ACTIVIN MEMBRANE-BOUND INHIBITOR HOMOLOG TGF-beta signaling pathway#P00052>BAMBI#P01287 MONDO|Ensembl=ENSMODG00000014740.4|UniProtKB=F6ZC14 F6ZC14 YWHAQ PTHR18860:SF3 14-3-3 PROTEIN 14-3-3 PROTEIN THETA scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539 MONDO|Ensembl=ENSMODG00000017487.4|UniProtKB=F7FEW5 F7FEW5 CCDC28B PTHR13400:SF2 CHEMOKINE C-C MOTIF RECEPTOR 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 28B plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011815.3|UniProtKB=A0A5F8GZQ9 A0A5F8GZQ9 RRP9 PTHR19865:SF0 U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2 U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2 nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515;RNA binding#GO:0003723;U3 snoRNA binding#GO:0034511 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000020697.4|UniProtKB=F7D1G4 F7D1G4 SRP72 PTHR14094:SF9 SIGNAL RECOGNITION PARTICLE 72 SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72 nucleic acid binding#GO:0003676;binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022 protein targeting#GO:0006605;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;protein targeting to membrane#GO:0006612;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;localization within membrane#GO:0051668 ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000011316.3|UniProtKB=F6WJ49 F6WJ49 LOC103092123 PTHR16675:SF67 MHC CLASS I-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000028008.2|UniProtKB=K7DZN6 K7DZN6 LOC100029656 PTHR46118:SF4 PROTEIN ABHD11 SN-1-SPECIFIC DIACYLGLYCEROL LIPASE ABHD11 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000014157.4|UniProtKB=F6UN69 F6UN69 VDAC1 PTHR11743:SF13 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL NON-SELECTIVE VOLTAGE-GATED ION CHANNEL VDAC1 monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;channel activity#GO:0015267;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;mitochondrial transport#GO:0006839;intracellular transport#GO:0046907;mitochondrial transmembrane transport#GO:1990542;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;plasma membrane#GO:0005886;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000018581.4|UniProtKB=A0A5F8GWH0 A0A5F8GWH0 PIK3CB PTHR10048:SF33 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT BETA ISOFORM phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 phosphatidylinositol phosphate biosynthetic process#GO:0046854;intracellular signal transduction#GO:0035556;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;cell motility#GO:0048870;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637;intracellular signaling cassette#GO:0141124;biosynthetic process#GO:0009058;biological regulation#GO:0065007;lipid biosynthetic process#GO:0008610;cell migration#GO:0016477;glycerophospholipid metabolic process#GO:0006650 intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 kinase#PC00137 Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;Ras Pathway#P04393>PI3K#P04567;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Interleukin signaling pathway#P00036>PI3K#P00990;p53 pathway feedback loops 2#P04398>PI3K#P04661;Axon guidance mediated by netrin#P00009>PI3K#P00363;Integrin signalling pathway#P00034>PI3K#P00936;Angiogenesis#P00005>PI3K#P00236;EGF receptor signaling pathway#P00018>PI3K#P00557;FGF signaling pathway#P00021>PI3K#P00640;B cell activation#P00010>PI3K#P00391;CCKR signaling map#P06959>p110#P07020;T cell activation#P00053>PI3K#P01322;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;PI3 kinase pathway#P00048>P110ACT#P01177;VEGF signaling pathway#P00056>PI3K#P01413;PI3 kinase pathway#P00048>p110#P01192 MONDO|Ensembl=ENSMODG00000010784.4|UniProtKB=A0A5F8GIH3 A0A5F8GIH3 DLEU7 PTHR36961:SF1 LEUKEMIA-ASSOCIATED PROTEIN 7 LEUKEMIA-ASSOCIATED PROTEIN 7 MONDO|Ensembl=ENSMODG00000018604.4|UniProtKB=A0A5F8HAW9 A0A5F8HAW9 NMNAT3 PTHR12039:SF7 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE_NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 3 adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;nucleotidyltransferase#PC00174 MONDO|Ensembl=ENSMODG00000021296.4|UniProtKB=A0A5F8GCI0 A0A5F8GCI0 TTC14 PTHR23184:SF9 TETRATRICOPEPTIDE REPEAT PROTEIN 14 TETRATRICOPEPTIDE REPEAT PROTEIN 14 MONDO|Ensembl=ENSMODG00000006714.4|UniProtKB=F7DGJ3 F7DGJ3 KLF6 PTHR23235:SF50 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 6 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000042852.1|UniProtKB=A0A5F8G849 A0A5F8G849 PTHR12015:SF102 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 22 cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cell motility#GO:0048870;regulation of cellular process#GO:0050794;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cell chemotaxis#GO:0060326;cytokine-mediated signaling pathway#GO:0019221;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cell migration#GO:0016477;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to peptide#GO:1901652;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;taxis#GO:0042330;response to chemical#GO:0042221;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000018975.4|UniProtKB=F7FPJ6 F7FPJ6 SLC22A7 PTHR24064:SF33 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 7 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;fatty acid transport#GO:0015908;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;lipid transport#GO:0006869;macromolecule localization#GO:0033036;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000014205.4|UniProtKB=F6TQU7 F6TQU7 ANKK1 PTHR24198:SF175 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000047244.1|UniProtKB=A0A5F8HHU0 A0A5F8HHU0 ZBTB38 PTHR24388:SF71 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 38 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000036549.1|UniProtKB=A0A5F8HII7 A0A5F8HII7 PHETA1 PTHR22902:SF17 SESQUIPEDALIAN SESQUIPEDALIAN-1 cellular component organization#GO:0016043;cytosolic transport#GO:0016482;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;metabolic process#GO:0008152;endosome organization#GO:0007032;vesicle organization#GO:0016050;endosomal transport#GO:0016197;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000049505.1|UniProtKB=A0A5F8G7C3 A0A5F8G7C3 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000037972.1|UniProtKB=A0A5F8H1B4 A0A5F8H1B4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003372.6|UniProtKB=F7CEX3 F7CEX3 MYO19 PTHR13140:SF289 MYOSIN UNCONVENTIONAL MYOSIN-XIX isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;microfilament motor activity#GO:0000146 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000022952.3|UniProtKB=K7E6C0 K7E6C0 IL4R PTHR23037:SF32 CYTOKINE RECEPTOR INTERLEUKIN-4 RECEPTOR SUBUNIT ALPHA cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;signaling#GO:0023052;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 MONDO|Ensembl=ENSMODG00000025310.2|UniProtKB=F7ENQ9 F7ENQ9 PTHR12021:SF27 THYMOSIN BETA THYMOSIN BETA-4-LIKE molecular sequestering activity#GO:0140313;binding#GO:0005488;actin binding#GO:0003779;protein sequestering activity#GO:0140311;cytoskeletal protein binding#GO:0008092;actin monomer binding#GO:0003785;protein binding#GO:0005515 regulation of cell migration#GO:0030334;regulation of biological process#GO:0050789;regulation of cell motility#GO:2000145;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of locomotion#GO:0040012 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000011044.3|UniProtKB=F7EN37 F7EN37 TMEM200B PTHR31815:SF3 AGAP005329-PA TRANSMEMBRANE PROTEIN 200B MONDO|Ensembl=ENSMODG00000045740.1|UniProtKB=A0A5F8G7R0 A0A5F8G7R0 MARCKS PTHR14353:SF9 MYRISTOYLATED ALANINE-RICH C-KINASE SUBSTRATE MARCKS MYRISTOYLATED ALANINE-RICH C-KINASE SUBSTRATE actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;actin filament organization#GO:0007015;developmental process#GO:0032502;central nervous system development#GO:0007417;actin cytoskeleton organization#GO:0030036;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;system development#GO:0048731;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029 actin cytoskeleton#GO:0015629;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;actin filament bundle#GO:0032432;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000044301.1|UniProtKB=A0A5F8G395 A0A5F8G395 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000000441.4|UniProtKB=F6UT36 F6UT36 CNTN5 PTHR12231:SF229 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN CONTACTIN-4 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000036486.1|UniProtKB=F7F066 F7F066 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000005319.4|UniProtKB=F7D2N6 F7D2N6 TBX15 PTHR11267:SF98 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX15 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;cell fate specification#GO:0001708;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 MONDO|Ensembl=ENSMODG00000042404.1|UniProtKB=A0A5F8H5B2 A0A5F8H5B2 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000044842.1|UniProtKB=A0A5F8H2N9 A0A5F8H2N9 PTHR19282:SF40 TETRASPANIN TETRASPANIN-4 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000048255.1|UniProtKB=F6ZCG0 F6ZCG0 LOC100022683 PTHR15327:SF0 MICROFIBRIL-ASSOCIATED PROTEIN MICROFIBRILLAR-ASSOCIATED PROTEIN 1 RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000046147.1|UniProtKB=A0A5F8HJD2 A0A5F8HJD2 PTHR19446:SF479 REVERSE TRANSCRIPTASES RNA-DIRECTED DNA POLYMERASE viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000038976.1|UniProtKB=A0A5F8GUM5 A0A5F8GUM5 PTHR11639:SF151 S100 CALCIUM-BINDING PROTEIN PROTEIN MRP-126 small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169 cellular process#GO:0009987;endothelial cell migration#GO:0043542;cell migration#GO:0016477;cell motility#GO:0048870 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000000101.2|UniProtKB=F6YC95 F6YC95 PTHR45635:SF13 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE 3 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000021097.2|UniProtKB=F6UIE2 F6UIE2 PTHR47958:SF216 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098 negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;gamete generation#GO:0007276;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;negative regulation of metabolic process#GO:0009892;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000013417.4|UniProtKB=F7CNI2 F7CNI2 PTHR21292:SF14 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3-LIKE PROTEIN 4 protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488 cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;exocytosis#GO:0006887;secretion by cell#GO:0032940 exocyst#GO:0000145;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000002520.4|UniProtKB=F7B948 F7B948 TRAF3IP3 PTHR15715:SF21 CENTROSOMAL PROTEIN OF 170 KDA TRAF3-INTERACTING JNK-ACTIVATING MODULATOR protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of innate immune response#GO:0045088;innate immune response#GO:0045087;positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to other organism#GO:0051707;activation of innate immune response#GO:0002218;immune response#GO:0006955;positive regulation of innate immune response#GO:0045089;cell communication#GO:0007154;response to virus#GO:0009615;intracellular signal transduction#GO:0035556;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;intracellular receptor signaling pathway#GO:0030522;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;antiviral innate immune response#GO:0140374;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;negative regulation of signal transduction#GO:0009968;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;cellular process#GO:0009987;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of hippo signaling#GO:0035331;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of hippo signaling#GO:0035330;negative regulation of biological process#GO:0048519;defense response to virus#GO:0051607;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000045300.1|UniProtKB=K7DZX8 K7DZX8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001895.4|UniProtKB=A0A5F8GJZ6 A0A5F8GJZ6 PKM PTHR11817:SF101 PYRUVATE KINASE PYRUVATE KINASE PKM pyruvate kinase activity#GO:0004743;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular response to chemical stimulus#GO:0070887;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;ADP catabolic process#GO:0046032;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;cellular response to oxygen-containing compound#GO:1901701;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;cellular response to insulin stimulus#GO:0032869;ADP metabolic process#GO:0046031;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;response to peptide hormone#GO:0043434;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;ribonucleoside diphosphate metabolic process#GO:0009185;response to endogenous stimulus#GO:0009719;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;pyridine nucleotide catabolic process#GO:0019364;cellular response to endogenous stimulus#GO:0071495;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;purine-containing compound catabolic process#GO:0072523;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;response to hormone#GO:0009725;response to chemical#GO:0042221;purine nucleotide catabolic process#GO:0006195;response to nitrogen compound#GO:1901698;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;carbohydrate metabolic process#GO:0005975;cellular response to peptide hormone stimulus#GO:0071375;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;cellular response to nitrogen compound#GO:1901699 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137 Glycolysis#P00024>Pyruvate kinase#P00675;Pyruvate metabolism#P02772>Pyruvate Kinase#P03132 MONDO|Ensembl=ENSMODG00000001374.4|UniProtKB=F7FJD4 F7FJD4 EFCAB7 PTHR46819:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7 regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;positive regulation of cellular process#GO:0048522 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;cell projection membrane#GO:0031253;cilium#GO:0005929;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000002432.4|UniProtKB=A0A5F8G271 A0A5F8G271 ADGRE5 PTHR12011:SF348 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E5 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000001796.4|UniProtKB=F6Z5F6 F6Z5F6 WDR72 PTHR44099:SF2 RABCONNECTIN-3B, ISOFORM A WD REPEAT-CONTAINING PROTEIN 72 protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000002630.4|UniProtKB=F7FUB4 F7FUB4 GGT7 PTHR11686:SF54 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 7 catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000038482.1|UniProtKB=A0A5F8GNT9 A0A5F8GNT9 PTHR13924:SF11 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 2 DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;binding#GO:0005488 establishment of localization#GO:0051234;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;neurogenesis#GO:0022008;intracellular transport#GO:0046907;transport#GO:0006810;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;anatomical structure development#GO:0048856;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;system development#GO:0048731;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;organelle localization#GO:0051640;cytoplasmic microtubule organization#GO:0031122;establishment of organelle localization#GO:0051656;cell differentiation#GO:0030154;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;nuclear migration#GO:0007097 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;spindle pole#GO:0000922;cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000009536.3|UniProtKB=A0A5F8GSM8 A0A5F8GSM8 LNPK PTHR22166:SF12 ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum tubular network organization#GO:0071786;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum tubular network#GO:0071782;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000041903.1|UniProtKB=A0A5F8H2K0 A0A5F8H2K0 RAMP1 PTHR14076:SF3 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RECEPTOR ACTIVITY-MODIFYING PROTEIN 1 coreceptor activity#GO:0015026;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization within membrane#GO:0051668;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;protein localization to plasma membrane#GO:0072659;intracellular protein localization#GO:0008104;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;macromolecule localization#GO:0033036;protein transport#GO:0015031;monoatomic ion transport#GO:0006811;cellular localization#GO:0051641;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;endocytosis#GO:0006897;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;protein localization to membrane#GO:0072657;calcium ion transport#GO:0006816;import into cell#GO:0098657;protein localization to cell periphery#GO:1990778;response to chemical#GO:0042221;vesicle-mediated transport#GO:0016192;signal transduction#GO:0007165;establishment of protein localization#GO:0045184;cellular process#GO:0009987;receptor internalization#GO:0031623;response to hormone#GO:0009725 signaling receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023669.3|UniProtKB=F6VXS7 F6VXS7 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000048479.1|UniProtKB=A0A5F8GYV1 A0A5F8GYV1 PTHR19446:SF479 REVERSE TRANSCRIPTASES RNA-DIRECTED DNA POLYMERASE viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000002342.3|UniProtKB=F7GLS7 F7GLS7 DRGX PTHR24329:SF542 HOMEOBOX PROTEIN ARISTALESS DORSAL ROOT GANGLIA HOMEOBOX PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell development#GO:0048468;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000004183.4|UniProtKB=F6QNK3 F6QNK3 CCDC81 PTHR14362:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 81 COILED-COIL DOMAIN-CONTAINING PROTEIN 81 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000004778.4|UniProtKB=F6WK67 F6WK67 PEMT PTHR15458:SF5 PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-methyltransferase activity#GO:0008170 metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;phosphatidylcholine biosynthetic process#GO:0006656;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000012882.4|UniProtKB=F7G293 F7G293 RGMA PTHR31428:SF4 RGM DOMAIN FAMILY MEMBER DRAG-1 REPULSIVE GUIDANCE MOLECULE A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;coreceptor activity#GO:0015026 regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000025451.3|UniProtKB=F6RKW1 F6RKW1 ADM2 PTHR23414:SF2 ADRENOMEDULLIN, ADM PROTEIN ADM2 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179 renal system process#GO:0003014;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of system process#GO:0044057;system process#GO:0003008;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of heart contraction#GO:0008016;signaling#GO:0023052;regulation of body fluid levels#GO:0050878;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000005118.3|UniProtKB=F6YQ34 F6YQ34 APOA2 PTHR11027:SF0 APOLIPOPROTEIN A-II APOLIPOPROTEIN A-II lipoprotein particle binding#GO:0071813;binding#GO:0005488;protein-lipid complex binding#GO:0071814;protein-containing complex binding#GO:0044877 organic hydroxy compound transport#GO:0015850;cholesterol homeostasis#GO:0042632;establishment of localization#GO:0051234;sterol transport#GO:0015918;localization#GO:0051179;chemical homeostasis#GO:0048878;transport#GO:0006810;lipid localization#GO:0010876;homeostatic process#GO:0042592;lipid transport#GO:0006869;cholesterol transport#GO:0030301;lipid homeostasis#GO:0055088;macromolecule localization#GO:0033036 high-density lipoprotein particle#GO:0034364;plasma lipoprotein particle#GO:0034358;lipoprotein particle#GO:1990777;protein-lipid complex#GO:0032994;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 apolipoprotein#PC00052;transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000010549.4|UniProtKB=F6YRP3 F6YRP3 RPA1 PTHR23273:SF4 REPLICATION FACTOR A 1, RFA1 REPLICATION PROTEIN A 70 KDA DNA-BINDING SUBUNIT nucleic acid binding#GO:0003676;binding#GO:0005488;damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162 macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA-templated DNA biosynthetic process#GO:0006278;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;reproductive process#GO:0022414;recombinational repair#GO:0000725;sexual reproduction#GO:0019953;telomere organization#GO:0032200;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;telomere maintenance via telomere lengthening#GO:0010833;telomere maintenance via telomerase#GO:0007004;nucleotide-excision repair#GO:0006289;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;cellular component organization#GO:0016043;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554 replisome#GO:0030894;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000004962.4|UniProtKB=A0A5F8GIH5 A0A5F8GIH5 DLG3 PTHR23119:SF28 DISCS LARGE DISKS LARGE HOMOLOG 3 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;binding#GO:0005488 regulation of biological quality#GO:0065008;cellular localization#GO:0051641;cell adhesion#GO:0007155;receptor clustering#GO:0043113;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;protein localization to synapse#GO:0035418;nervous system development#GO:0007399;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;system development#GO:0048731;cell communication#GO:0007154;localization#GO:0051179;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;anatomical structure development#GO:0048856;localization within membrane#GO:0051668;establishment or maintenance of bipolar cell polarity#GO:0061245;protein localization to cell junction#GO:1902414;establishment or maintenance of apical/basal cell polarity#GO:0035088;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;intracellular protein localization#GO:0008104;developmental process#GO:0032502;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;macromolecule localization#GO:0033036 postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;cell junction#GO:0030054;neuromuscular junction#GO:0031594 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000028758.2|UniProtKB=K7E1E2 K7E1E2 PTHR21713:SF38 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED NAC ALPHA DOMAIN CONTAINING establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein targeting#GO:0006605;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000002980.4|UniProtKB=F6Q505 F6Q505 ATP1B1 PTHR11523:SF10 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;export from cell#GO:0140352;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801 ATPase dependent transmembrane transport complex#GO:0098533;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cation-transporting ATPase complex#GO:0090533;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000012166.3|UniProtKB=A0A5F8GF12 A0A5F8GF12 FAM117A PTHR14972:SF7 AGAP011572-PA PROTEIN FAM117A MONDO|Ensembl=ENSMODG00000042765.1|UniProtKB=A0A5F8G6Q2 A0A5F8G6Q2 PTHR47409:SF2 HOMEOBOX PROTEIN PROPHET OF PIT-1 HOMEOBOX PROTEIN PROPHET OF PIT-1 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000016001.4|UniProtKB=F7EYX5 F7EYX5 PTHR23382:SF1 MALATE DEHYDROGENASE MALATE DEHYDROGENASE 1B-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;pyridine-containing compound metabolic process#GO:0072524;oxoacid metabolic process#GO:0043436;nucleotide metabolic process#GO:0009117;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000019294.4|UniProtKB=F6RZD4 F6RZD4 FAM47E PTHR46449:SF5 ZGC:158260 FAMILY WITH SEQUENCE SIMILARITY 47 MEMBER E positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;transcription initiation-coupled chromatin remodeling#GO:0045815;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;chromatin remodeling#GO:0006338;DNA-templated transcription initiation#GO:0006352;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;transcription by RNA polymerase II#GO:0006366;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of biosynthetic process#GO:0009891 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785 MONDO|Ensembl=ENSMODG00000043860.1|UniProtKB=A0A5F8GW14 A0A5F8GW14 DDA1 PTHR31879:SF2 DET1- AND DDB1-ASSOCIATED PROTEIN 1 DET1- AND DDB1-ASSOCIATED PROTEIN 1 regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of metabolic process#GO:0009893;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of protein metabolic process#GO:0051247;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 MONDO|Ensembl=ENSMODG00000018151.3|UniProtKB=F7CWU0 F7CWU0 PTHR21139:SF2 TRIOSEPHOSPHATE ISOMERASE TRIOSEPHOSPHATE ISOMERASE isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824 energy derivation by oxidation of organic compounds#GO:0015980;nucleotide catabolic process#GO:0009166;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleoside diphosphate catabolic process#GO:0009134;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;glucose metabolic process#GO:0006006;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound catabolic process#GO:0072523;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP metabolic process#GO:0046034;aldehyde metabolic process#GO:0006081;nicotinamide nucleotide metabolic process#GO:0046496;gluconeogenesis#GO:0006094;oxoacid metabolic process#GO:0043436;glyceraldehyde-3-phosphate metabolic process#GO:0019682;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;ribonucleoside diphosphate metabolic process#GO:0009185;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ADP catabolic process#GO:0046032;carbohydrate biosynthetic process#GO:0016051;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;pyruvate metabolic process#GO:0006090;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163 isomerase#PC00135;metabolite interconversion enzyme#PC00262 Glycolysis#P00024>Triosephosphate isomerase#P00673 MONDO|Ensembl=ENSMODG00000015318.3|UniProtKB=F6XYA9 F6XYA9 ZFAND2B PTHR14677:SF13 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED AN1-TYPE ZINC FINGER PROTEIN 2B modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;localization#GO:0051179;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein targeting#GO:0006605;catabolic process#GO:0009056;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein targeting to ER#GO:0045047;cellular process#GO:0009987;establishment of protein localization#GO:0045184;proteasomal protein catabolic process#GO:0010498;establishment of protein localization to endoplasmic reticulum#GO:0072599 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000010063.4|UniProtKB=F6Y574 F6Y574 PQBP1 PTHR21737:SF3 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 POLYGLUTAMINE-BINDING PROTEIN 1 binding#GO:0005488;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 membraneless organelle#GO:0043228;nuclear body#GO:0016604;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019995.3|UniProtKB=F6RN82 F6RN82 LOC103097439 PTHR48018:SF52 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000051485.1|UniProtKB=F6VFH2 F6VFH2 LOC100009891 PTHR26454:SF0 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048739.1|UniProtKB=A0A5F8HI25 A0A5F8HI25 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000042908.1|UniProtKB=A0A5F8GIL4 A0A5F8GIL4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009539.4|UniProtKB=F7C419 F7C419 RPL3 PTHR11363:SF4 60S RIBOSOMAL PROTEIN L3-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL3 RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000020814.3|UniProtKB=F6RN34 F6RN34 KLK13 PTHR24271:SF3 KALLIKREIN-RELATED KALLIKREIN-13 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000019452.3|UniProtKB=F6RXE5 F6RXE5 FURIN PTHR42884:SF1 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED FURIN serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 protein maturation#GO:0051604;gene expression#GO:0010467;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;biosynthetic process#GO:0009058;peptide hormone processing#GO:0016486;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of biological quality#GO:0065008;proteolysis#GO:0006508 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Endothelin signaling pathway#P00019>furin#P00575 MONDO|Ensembl=ENSMODG00000010398.3|UniProtKB=F7A7N8 F7A7N8 PTHR11280:SF8 GLUCOSAMINE-6-PHOSPHATE ISOMERASE GLUCOSAMINE-6-PHOSPHATE DEAMINASE 1 catalytic activity#GO:0003824;binding#GO:0005488;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;protein binding#GO:0005515;identical protein binding#GO:0042802;deaminase activity#GO:0019239 amino sugar catabolic process#GO:0046348;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carbohydrate derivative metabolic process#GO:1901135 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 isomerase#PC00135 N-acetylglucosamine metabolism#P02756>Glucosamine-6-phosphate deaminase#P03041 MONDO|Ensembl=ENSMODG00000017838.2|UniProtKB=F6Z8U8 F6Z8U8 CALHM4 PTHR32261:SF5 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 4 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000017643.3|UniProtKB=F6Z972 F6Z972 CAP1 PTHR10652:SF1 ADENYLYL CYCLASE-ASSOCIATED PROTEIN ADENYLYL CYCLASE-ASSOCIATED PROTEIN 1 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515 actin filament-based process#GO:0030029;developmental process#GO:0032502;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;anatomical structure development#GO:0048856;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cell morphogenesis#GO:0000902;actin cytoskeleton organization#GO:0030036 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000005516.4|UniProtKB=F7CGP7 F7CGP7 LOC100023235 PTHR24300:SF400 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C9 tetrapyrrole binding#GO:0046906;binding#GO:0005488;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037 arachidonate metabolic process#GO:0019369;cellular response to stimulus#GO:0051716;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;icosanoid metabolic process#GO:0006690;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000024011.2|UniProtKB=A0A5F8H8U7 A0A5F8H8U7 PTHR11588:SF43 TUBULIN TUBULIN BETA-3 CHAIN guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166 organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;system development#GO:0048731 microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;tubulin#PC00228 Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780 MONDO|Ensembl=ENSMODG00000007421.4|UniProtKB=A0A5F8GGE3 A0A5F8GGE3 RYR2 PTHR46399:SF7 B30.2/SPRY DOMAIN-CONTAINING PROTEIN RYANODINE RECEPTOR 2 transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267 transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;calcium ion transmembrane transport#GO:0070588;muscle system process#GO:0003012;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;system process#GO:0003008;transport#GO:0006810;muscle contraction#GO:0006936;multicellular organismal process#GO:0032501;release of sequestered calcium ion into cytosol by sarcoplasmic reticulum#GO:0014808;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209 organelle membrane#GO:0031090;membraneless organelle#GO:0043228;sarcolemma#GO:0042383;I band#GO:0031674;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886;endomembrane system#GO:0012505;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;Z disc#GO:0030018;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;endoplasmic reticulum subcompartment#GO:0098827;sarcoplasm#GO:0016528;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;bounding membrane of organelle#GO:0098588;transporter complex#GO:1990351;sarcomere#GO:0030017;endoplasmic reticulum#GO:0005783;cation channel complex#GO:0034703;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;sarcoplasmic reticulum membrane#GO:0033017;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;contractile muscle fiber#GO:0043292;sarcoplasmic reticulum#GO:0016529;organelle subcompartment#GO:0031984;supramolecular fiber#GO:0099512;myofibril#GO:0030016;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;calcium channel complex#GO:0034704 CCKR signaling map#P06959>RYR1/2/3#P07088;Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441 MONDO|Ensembl=ENSMODG00000019744.4|UniProtKB=F6WNS4 F6WNS4 PTHR12011:SF58 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR D2 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004825.5|UniProtKB=F6RR27 F6RR27 IRS2 PTHR10614:SF7 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 2 molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;receptor tyrosine kinase binding#GO:0030971;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;enzyme binding#GO:0019899;protein binding#GO:0005515;signaling adaptor activity#GO:0035591 cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;signal transduction#GO:0007165;response to hormone#GO:0009725;response to peptide hormone#GO:0043434;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;cellular response to insulin stimulus#GO:0032869;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;insulin-like growth factor receptor signaling pathway#GO:0048009;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887;Gonadotropin-releasing hormone receptor pathway#P06664>IRS#P06759;Interleukin signaling pathway#P00036>IRS1/2#P00980;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899 MONDO|Ensembl=ENSMODG00000050026.1|UniProtKB=A0A5F8GRF6 A0A5F8GRF6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000463.5|UniProtKB=F6URM4 F6URM4 HOXA10 PTHR45874:SF1 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN HOX-A10 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000043878.1|UniProtKB=A0A5F8GQL7 A0A5F8GQL7 PSMD8 PTHR12387:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;proteasome complex#GO:0000502;nucleus#GO:0005634 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000005998.3|UniProtKB=F6SKZ7 F6SKZ7 LOC100021638 PTHR10885:SF24 ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824 isoprenoid biosynthetic process#GO:0008299;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;isoprenoid metabolic process#GO:0006720;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 isomerase#PC00135 MONDO|Ensembl=ENSMODG00000020587.4|UniProtKB=A0A5F8GNY9 A0A5F8GNY9 SEC24B PTHR13803:SF42 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24B SNARE binding#GO:0000149;zinc ion binding#GO:0008270;cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192 ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle coat#GO:0030120;cytoplasm#GO:0005737;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000016371.3|UniProtKB=A0A5F8GZI3 A0A5F8GZI3 VASN PTHR24373:SF261 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN VASORIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015874.3|UniProtKB=F7BR65 F7BR65 MRTO4 PTHR45841:SF1 MRNA TURNOVER PROTEIN 4 MRTO4 MRNA TURNOVER PROTEIN 4 HOMOLOG cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;rRNA processing#GO:0006364 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000023490.1|UniProtKB=F7EZP3 F7EZP3 RGS9BP PTHR21029:SF1 R-SEVEN BINDING PROTEIN (R7BP) HOMOLOG REGULATOR OF G PROTEIN SIGNALING 9-BINDING PROTEIN cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;visual perception#GO:0007601;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;sensory perception of light stimulus#GO:0050953;system process#GO:0003008;response to external stimulus#GO:0009605;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;response to radiation#GO:0009314;signal transduction#GO:0007165;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 neuron projection#GO:0043005;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000043430.1|UniProtKB=A0A5F8HCC6 A0A5F8HCC6 PTHR13420:SF7 UPF0235 PROTEIN C15ORF40 UPF0235 PROTEIN C15ORF40 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000007857.4|UniProtKB=F7EBI9 F7EBI9 CPAP PTHR10331:SF23 T COMPLEX PROTEIN 10 CENTROSOMAL P4.1-ASSOCIATED PROTEIN protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cilium assembly#GO:0060271;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000005069.4|UniProtKB=F7ASH5 F7ASH5 SNAPC2 PTHR15132:SF1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 2 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 2 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear body#GO:0016604;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000050815.1|UniProtKB=F6V7J9 F6V7J9 LOC100018133 PTHR48002:SF146 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4X2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037955.1|UniProtKB=A0A5F8GFZ0 A0A5F8GFZ0 CPLX2 PTHR16705:SF9 COMPLEXIN COMPLEXIN-2 binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515 regulation of localization#GO:0032879;regulation of transport#GO:0051049;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;regulated exocytosis#GO:0045055;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;synaptic signaling#GO:0099536;secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of signaling#GO:0023051;signaling#GO:0023052;export from cell#GO:0140352;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268 intracellular anatomical structure#GO:0005622;axon#GO:0030424;cellular anatomical structure#GO:0110165;synapse#GO:0045202;SNARE complex#GO:0031201;neuron projection terminus#GO:0044306;cell projection#GO:0042995;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;terminal bouton#GO:0043195;membrane protein complex#GO:0098796;cell junction#GO:0030054;axon terminus#GO:0043679;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;neuron projection#GO:0043005;presynapse#GO:0098793 MONDO|Ensembl=ENSMODG00000019316.3|UniProtKB=H9H7A9 H9H7A9 IFITM10 PTHR13999:SF9 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 10 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000049244.1|UniProtKB=A0A5F8GLA2 A0A5F8GLA2 PTHR11984:SF3 CONNEXIN GAP JUNCTION DELTA-4 PROTEIN wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;regulation of biological process#GO:0050789;cellular process#GO:0009987 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;cell junction#GO:0030054 cell junction protein#PC00070;gap junction#PC00105 MONDO|Ensembl=ENSMODG00000002481.4|UniProtKB=F7BVV4 F7BVV4 UROD PTHR21091:SF169 METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED UROPORPHYRINOGEN DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound biosynthetic process#GO:0006779;cellular process#GO:0009987;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;tetrapyrrole biosynthetic process#GO:0033014 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155 Heme biosynthesis#P02746>Uroporphyrinogen decarboxylase#P02975 MONDO|Ensembl=ENSMODG00000019633.4|UniProtKB=A0A5F8H4F4 A0A5F8H4F4 FBXW2 PTHR44436:SF1 F-BOX/WD REPEAT-CONTAINING PROTEIN 2 F-BOX_WD REPEAT-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000023276.1|UniProtKB=F6SWT4 F6SWT4 LOC100027785 PTHR18847:SF0 20 KD NUCLEAR CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mRNA processing#GO:0006397;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA localization#GO:0006403;RNA transport#GO:0050658;regulation of cellular process#GO:0050794;nucleobase-containing compound transport#GO:0015931;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;nucleocytoplasmic transport#GO:0006913;RNA splicing, via transesterification reactions#GO:0000375;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;localization#GO:0051179;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;nitrogen compound transport#GO:0071705;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;macromolecule localization#GO:0033036;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;transport#GO:0006810;RNA export from nucleus#GO:0006405;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000015331.3|UniProtKB=F6XFI1 F6XFI1 LOC100022399 PTHR26453:SF17 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038043.1|UniProtKB=A0A5F8GZP0 A0A5F8GZP0 PTHR24377:SF975 IP01015P-RELATED ZINC FINGER PROTEIN 883-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006914.3|UniProtKB=F6PSH1 F6PSH1 RRP7A PTHR13191:SF0 RIBOSOMAL RNA PROCESSING PROTEIN 7-RELATED RIBOSOMAL RNA-PROCESSING PROTEIN 7 HOMOLOG A-RELATED protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;90S preribosome#GO:0030686;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000008452.4|UniProtKB=F7GEZ0 F7GEZ0 TOMM20 PTHR12430:SF2 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 HOMOLOG intracellular transport#GO:0046907;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;RNA transport#GO:0050658;mitochondrial transport#GO:0006839;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236 cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000004537.4|UniProtKB=F6U963 F6U963 MTHFSD PTHR13017:SF0 5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE-RELATED METHENYLTETRAHYDROFOLATE SYNTHASE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;ligase#PC00142 MONDO|Ensembl=ENSMODG00000002252.4|UniProtKB=F7CWL7 F7CWL7 SANBR PTHR20946:SF0 SANT AND BTB DOMAIN REGULATOR OF CLASS SWITCH RECOMBINATION SANT AND BTB DOMAIN REGULATOR OF CLASS SWITCH RECOMBINATION production of molecular mediator of immune response#GO:0002440;response to stimulus#GO:0050896;immune system development#GO:0002520;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;cell activation involved in immune response#GO:0002263;immunoglobulin mediated immune response#GO:0016064;B cell activation involved in immune response#GO:0002312;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;gene expression#GO:0010467;lymphocyte activation#GO:0046649;cellular process#GO:0009987;somatic recombination of immunoglobulin gene segments#GO:0016447;lymphocyte activation involved in immune response#GO:0002285;multicellular organism development#GO:0007275;B cell activation#GO:0042113;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;immune effector process#GO:0002252;leukocyte activation involved in immune response#GO:0002366;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;leukocyte activation#GO:0045321;somatic diversification of immune receptors#GO:0002200;anatomical structure development#GO:0048856;system development#GO:0048731;cell activation#GO:0001775;multicellular organismal process#GO:0032501;adaptive immune response#GO:0002250;somatic cell DNA recombination#GO:0016444;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502 MONDO|Ensembl=ENSMODG00000015632.2|UniProtKB=F7FEM4 F7FEM4 USP39 PTHR21646:SF16 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 39 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;regulation of protein stability#GO:0031647;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000009243.4|UniProtKB=F7EDM7 F7EDM7 DKC1 PTHR23127:SF0 CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1 catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;mRNA modification#GO:0016556;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654 ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077;centromere DNA-binding protein#PC00071 MONDO|Ensembl=ENSMODG00000018809.4|UniProtKB=F6Z032 F6Z032 CTSS PTHR12411:SF1077 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN S endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000046139.1|UniProtKB=A0A5F8HHP4 A0A5F8HHP4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000048424.1|UniProtKB=F6RLE5 F6RLE5 PTHR11909:SF20 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of canonical Wnt signaling pathway#GO:0060828 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242;Hedgehog signaling pathway#P00025>Casein kinase I#P00681 MONDO|Ensembl=ENSMODG00000009978.4|UniProtKB=F6Y7C7 F6Y7C7 ARG2 PTHR43782:SF4 ARGINASE ARGINASE-2, MITOCHONDRIAL hydrolase activity#GO:0016787;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;small molecule metabolic process#GO:0044281;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;oxoacid metabolic process#GO:0043436;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of multicellular organismal process#GO:0051239;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 mitochondrion#GO:0005739;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000017314.4|UniProtKB=F6XCJ8 F6XCJ8 CRTC2 PTHR13589:SF6 CREB-REGULATED TRANSCRIPTION COACTIVATOR CREB-REGULATED TRANSCRIPTION COACTIVATOR 2 transcription factor binding#GO:0008134;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000005964.3|UniProtKB=F6W095 F6W095 LOC100025872 PTHR11848:SF226 TGF-BETA FAMILY LEFT-RIGHT DETERMINATION FACTOR cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 response to endogenous stimulus#GO:0009719;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;pattern specification process#GO:0007389;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;regionalization#GO:0003002;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;anterior/posterior axis specification#GO:0009948;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113;TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000011266.4|UniProtKB=A0A5F8H1E9 A0A5F8H1E9 KLHL13 PTHR45632:SF11 LD33804P KELCH-LIKE PROTEIN 13 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of cell cycle#GO:0051726;catabolic process#GO:0009056;regulation of cellular process#GO:0050794 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006338.4|UniProtKB=F7AG42 F7AG42 ANKS3 PTHR24184:SF6 SI:CH211-189E2.2 ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 3 cilium#GO:0005929;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000012652.3|UniProtKB=F6V6B7 F6V6B7 PTHR23267:SF176 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 8-61 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000014624.4|UniProtKB=F6YPW4 F6YPW4 MODO-UE PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;antigen binding#GO:0003823;peptide binding#GO:0042277 regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000014831.4|UniProtKB=F7CHW1 F7CHW1 PTHR24100:SF149 BUTYROPHILIN BG ANTIGEN 1, MHCB REGION-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;cell communication#GO:0007154 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000006053.4|UniProtKB=F7FSJ9 F7FSJ9 FAM20B PTHR12450:SF14 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 GLYCOSAMINOGLYCAN XYLOSYLKINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000001889.4|UniProtKB=F6WGL5 F6WGL5 FUS PTHR23238:SF5 RNA BINDING PROTEIN RNA-BINDING PROTEIN FUS nucleic acid binding#GO:0003676;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;RNA binding#GO:0003723 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000016179.4|UniProtKB=F6PY30 F6PY30 CLCN7 PTHR11689:SF169 CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER H(+)_CL(-) EXCHANGE TRANSPORTER 7 passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;proton transmembrane transporter activity#GO:0015078;chloride channel activity#GO:0005254;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;active transmembrane transporter activity#GO:0022804;monoatomic anion channel activity#GO:0005253;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770;monoatomic ion channel complex#GO:0034702;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000037787.1|UniProtKB=A0A5F8H0S1 A0A5F8H0S1 PTHR26452:SF930 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009390.4|UniProtKB=F7CPH5 F7CPH5 PTHR18952:SF84 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 14 catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000012761.4|UniProtKB=A0A5F8HGW3 A0A5F8HGW3 IGF1R PTHR24416:SF106 TYROSINE-PROTEIN KINASE RECEPTOR INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713 regulation of response to stimulus#GO:0048583;cellular response to insulin stimulus#GO:0032869;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;positive regulation of cellular process#GO:0048522;response to glucose#GO:0009749;cellular response to nitrogen compound#GO:1901699;positive regulation of response to stimulus#GO:0048584;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;response to nitrogen compound#GO:1901698;positive regulation of signal transduction#GO:0009967;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;cellular response to peptide hormone stimulus#GO:0071375;homeostatic process#GO:0042592;cellular response to glucose stimulus#GO:0071333;cell surface receptor signaling pathway#GO:0007166;chemical homeostasis#GO:0048878;regulation of MAPK cascade#GO:0043408;regulation of JNK cascade#GO:0046328;glucose homeostasis#GO:0042593;response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to chemical#GO:0042221;regulation of intracellular signal transduction#GO:1902531;response to monosaccharide#GO:0034284;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;positive regulation of signaling#GO:0023056;response to carbohydrate#GO:0009743;intracellular glucose homeostasis#GO:0001678;response to hexose#GO:0009746;response to endogenous stimulus#GO:0009719;carbohydrate homeostasis#GO:0033500;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;insulin-like growth factor receptor signaling pathway#GO:0048009;signaling#GO:0023052 axon#GO:0030424;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;signaling receptor complex#GO:0043235;protein kinase complex#GO:1902911;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885;Gonadotropin-releasing hormone receptor pathway#P06664>IGF-1R#P06703;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882 MONDO|Ensembl=ENSMODG00000038411.1|UniProtKB=K7DZN8 K7DZN8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000047667.1|UniProtKB=F6S944 F6S944 LOC100015179 PTHR26452:SF55 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023809.2|UniProtKB=F6QLJ8 F6QLJ8 LOC100014181 PTHR48001:SF39 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012183.4|UniProtKB=F7CXY8 F7CXY8 CCDC150 PTHR35352:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 150 COILED-COIL DOMAIN-CONTAINING PROTEIN 150 MONDO|Ensembl=ENSMODG00000046342.1|UniProtKB=A0A5F8H161 A0A5F8H161 PTHR21141:SF120 60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN P2 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000020526.4|UniProtKB=A0A5F8GBL6 A0A5F8GBL6 RELL1 PTHR31037:SF1 RELT-LIKE PROTEIN 1-RELATED RELT-LIKE PROTEIN 1 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000036758.1|UniProtKB=A0A5F8HHP2 A0A5F8HHP2 LOC100033136 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000016296.4|UniProtKB=F7E4H4 F7E4H4 NMD3 PTHR12746:SF2 NONSENSE-MEDIATED MRNA DECAY PROTEIN 3 60S RIBOSOMAL EXPORT PROTEIN NMD3 protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;ribosomal large subunit binding#GO:0043023;binding#GO:0005488 organelle localization#GO:0051640;ribosome biogenesis#GO:0042254;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;ribosomal large subunit export from nucleus#GO:0000055;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000006440.5|UniProtKB=A0A5F8G635 A0A5F8G635 TPST1 PTHR12788:SF4 PROTEIN-TYROSINE SULFOTRANSFERASE 2 PROTEIN-TYROSINE SULFOTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220 CCKR signaling map#P06959>Protein tyrosine sulfotransferase#P07148 MONDO|Ensembl=ENSMODG00000048142.1|UniProtKB=A0A5F8GNX6 A0A5F8GNX6 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000007290.4|UniProtKB=F7FCF7 F7FCF7 MRPS7 PTHR11205:SF19 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7M structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;mRNA binding#GO:0003729 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 ribosome#GO:0005840;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000017358.5|UniProtKB=F6VYZ1 F6VYZ1 CCAR1 PTHR14304:SF14 CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000018899.4|UniProtKB=P48798 P48798 FGF2 PTHR11486:SF83 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 2 protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 nervous system development#GO:0007399;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;system development#GO:0048731;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 growth factor#PC00112;intercellular signal molecule#PC00207 Angiogenesis#P00005>FGF#P00213;FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000006220.3|UniProtKB=F7FS96 F7FS96 CHMP4C PTHR22761:SF77 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 4C late endosome to vacuole transport#GO:0045324;membrane assembly#GO:0071709;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;endosome transport via multivesicular body sorting pathway#GO:0032509;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;vesicle budding from membrane#GO:0006900;nuclear envelope organization#GO:0006998;vesicle organization#GO:0016050;endosomal transport#GO:0016197;nucleus organization#GO:0006997;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907 cytoplasmic side of membrane#GO:0098562;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;nucleus#GO:0005634;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;nuclear envelope#GO:0005635;plasma membrane#GO:0005886;cytoplasm#GO:0005737;late endosome#GO:0005770;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;cytoplasmic side of plasma membrane#GO:0009898;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000036477.1|UniProtKB=A0A5F8G994 A0A5F8G994 PTHR22749:SF14 RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE RIBOFLAVIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;flavin-containing compound metabolic process#GO:0042726;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 Flavin biosynthesis#P02741>FAD synthetase#P02936;Flavin biosynthesis#P02741>Riboflavin kinase#P02934 MONDO|Ensembl=ENSMODG00000042727.1|UniProtKB=A0A5F8HIU4 A0A5F8HIU4 INHBB PTHR11848:SF29 TGF-BETA FAMILY INHIBIN BETA B CHAIN receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>Inhba/b#P06700;TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000042222.1|UniProtKB=A0A5F8H056 A0A5F8H056 EXTL3 PTHR11062:SF73 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-LIKE 3 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000049757.1|UniProtKB=A0A5F8GAR2 A0A5F8GAR2 monDomV1R1257 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004285.2|UniProtKB=F6TDT4 F6TDT4 TLCD4 PTHR13439:SF1 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 4 chemical homeostasis#GO:0048878;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000036430.1|UniProtKB=A0A5F8G3R5 A0A5F8G3R5 PDE11A PTHR11347:SF130 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE DUAL 3',5'-CYCLIC-AMP AND -GMP PHOSPHODIESTERASE 11A hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585 hydrolase#PC00121;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000005584.4|UniProtKB=A0A5F8H9B3 A0A5F8H9B3 RAVER1 PTHR23189:SF46 RNA RECOGNITION MOTIF-CONTAINING RIBONUCLEOPROTEIN PTB-BINDING 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000036658.1|UniProtKB=F7BFK2 F7BFK2 VN2R644 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000025074.2|UniProtKB=F6RQ81 F6RQ81 LOC100016275 PTHR12002:SF84 CLAUDIN CLAUDIN-24 cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840 cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;apical junction complex#GO:0043296;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 cell junction protein#PC00070;tight junction#PC00214 MONDO|Ensembl=ENSMODG00000024943.2|UniProtKB=F6VDC8 F6VDC8 ASCL4 PTHR13935:SF51 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE HOMOLOG 4 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000002171.4|UniProtKB=F7GEI7 F7GEI7 NIT2 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000003027.3|UniProtKB=A0A5F8H9X3 A0A5F8H9X3 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014503.4|UniProtKB=F7FLU8 F7FLU8 WASF2 PTHR12902:SF6 WASP-1 ACTIN-BINDING PROTEIN WASF2 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;protein kinase A regulatory subunit binding#GO:0034237;binding#GO:0005488;protein kinase A binding#GO:0051018 actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of organelle organization#GO:0010638;actin filament-based process#GO:0030029;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125 cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;cell leading edge#GO:0031252;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000007565.4|UniProtKB=F7FPN5 F7FPN5 LOC103101823 PTHR24376:SF210 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 721-RELATED gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000041849.1|UniProtKB=A0A5F8H6H3 A0A5F8H6H3 VN2R630 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000016245.3|UniProtKB=F7C2A1 F7C2A1 LOC100013147 PTHR26453:SF23 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13C9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000302.4|UniProtKB=F6WAF9 F6WAF9 C1orf52 PTHR31833:SF2 UPF0690 PROTEIN C1ORF52 UPF0690 PROTEIN C1ORF52 MONDO|Ensembl=ENSMODG00000014490.3|UniProtKB=A0A5F8GDR0 A0A5F8GDR0 GPR3 PTHR22750:SF39 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 3 bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000023904.1|UniProtKB=F7CMJ8 F7CMJ8 CNR2 PTHR22750:SF10 G-PROTEIN COUPLED RECEPTOR CANNABINOID RECEPTOR 2 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000024132.2|UniProtKB=F6XZ86 F6XZ86 LOC100618884 PTHR23430:SF458 HISTONE H2A LATE HISTONE H2A.L3 structural molecule activity#GO:0005198 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;heterochromatin organization#GO:0070828;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000007377.2|UniProtKB=F6ZNI5 F6ZNI5 MAS1 PTHR11334:SF61 MAS-RELATED G-PROTEIN COUPLED RECEPTOR PROTO-ONCOGENE MAS signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000460.5|UniProtKB=F6US32 F6US32 LGI2 PTHR24367:SF21 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH REPEAT LGI FAMILY MEMBER 2 anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;synapse assembly#GO:0007416;cell junction organization#GO:0034330;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000007039.4|UniProtKB=F6UFM0 F6UFM0 LAMC2 PTHR10574:SF313 NETRIN/LAMININ-RELATED LAMININ SUBUNIT GAMMA-2 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;cellular process#GO:0009987;tissue development#GO:0009888;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 MONDO|Ensembl=ENSMODG00000003553.4|UniProtKB=F7GBF3 F7GBF3 LYPD6 PTHR31171:SF0 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 6 LY6_PLAUR DOMAIN-CONTAINING PROTEIN 6 molecular function regulator activity#GO:0098772;neurotransmitter receptor regulator activity#GO:0099602;signaling receptor regulator activity#GO:0030545;acetylcholine receptor regulator activity#GO:0030548 MONDO|Ensembl=ENSMODG00000005136.2|UniProtKB=F7EQH3 F7EQH3 ARPC4 PTHR22629:SF0 ARP2/3 COMPLEX 20 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 4 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular component organization#GO:0016043;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 MONDO|Ensembl=ENSMODG00000000757.4|UniProtKB=F6T8G2 F6T8G2 LCORL PTHR21545:SF10 TRANSCRIPTION FACTOR MLR1/2 LIGAND-DEPENDENT NUCLEAR RECEPTOR COREPRESSOR-LIKE PROTEIN regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000044342.1|UniProtKB=A0A5F8HJF5 A0A5F8HJF5 NPTX1 PTHR19277:SF24 PENTRAXIN NEURONAL PENTRAXIN-1 multicellular organismal process#GO:0032501;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000041485.1|UniProtKB=A0A5F8H9B1 A0A5F8H9B1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000006628.4|UniProtKB=A0A5F8GBM7 A0A5F8GBM7 GPRC5B PTHR14511:SF9 G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5 G PROTEIN-COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER B enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;binding#GO:0005488;kinase binding#GO:0019900;kinase activator activity#GO:0019209;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function activator activity#GO:0140677 cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;signaling receptor complex#GO:0043235;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000003525.4|UniProtKB=A0A5F8GD32 A0A5F8GD32 SLC24A2 PTHR10846:SF41 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 2 monoatomic cation channel activity#GO:0005261;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;chemical homeostasis#GO:0048878;monoatomic cation transmembrane transport#GO:0098655;regulation of trans-synaptic signaling#GO:0099177;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;negative regulation of cell communication#GO:0010648;positive regulation of signaling#GO:0023056;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;calcium ion homeostasis#GO:0055074;positive regulation of synaptic transmission#GO:0050806;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;regulation of synaptic plasticity#GO:0048167;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;positive regulation of cellular process#GO:0048522;monoatomic cation transport#GO:0006812;localization#GO:0051179;metal ion transport#GO:0030001;homeostatic process#GO:0042592;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000008369.4|UniProtKB=F7CDY2 F7CDY2 SGCG PTHR12939:SF4 SARCOGLYCAN GAMMA-SARCOGLYCAN tissue development#GO:0009888;multicellular organismal process#GO:0032501;heart development#GO:0007507;blood circulation#GO:0008015;animal organ development#GO:0048513;cardiac muscle tissue development#GO:0048738;multicellular organism development#GO:0007275;heart contraction#GO:0060047;system process#GO:0003008;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;circulatory system development#GO:0072359;heart process#GO:0003015;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;system development#GO:0048731;circulatory system process#GO:0003013;animal gross anatomical part developmental process#GO:0160108 sarcolemma#GO:0042383;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000003970.2|UniProtKB=F7FMF1 F7FMF1 PTHR23008:SF0 CHROMOSOME 28 C10ORF62 HOMOLOG CHROMOSOME 10 OPEN READING FRAME 62 MONDO|Ensembl=ENSMODG00000038440.1|UniProtKB=A0A5F8GSI7 A0A5F8GSI7 PTHR14503:SF4 MITOCHONDRIAL RIBOSOMAL PROTEIN 34 FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN BL34M membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000010455.4|UniProtKB=F7F7R9 F7F7R9 PTHR14455:SF0 ASKOPOS S100P-BINDING PROTEIN MONDO|Ensembl=ENSMODG00000011054.4|UniProtKB=F7EMM5 F7EMM5 SLC47A1 PTHR11206:SF73 MULTIDRUG RESISTANCE PROTEIN MULTIDRUG AND TOXIN EXTRUSION PROTEIN 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;xenobiotic transmembrane transporter activity#GO:0042910 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000036654.1|UniProtKB=A0A5F8HG41 A0A5F8HG41 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000015349.4|UniProtKB=F6WY92 F6WY92 PDCD1LG2 PTHR25466:SF1 T-LYMPHOCYTE ACTIVATION ANTIGEN PROGRAMMED CELL DEATH 1 LIGAND 2 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 negative regulation of signal transduction#GO:0009968;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;immune response#GO:0006955;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;immune system process#GO:0002376;negative regulation of signaling#GO:0023057 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000002874.3|UniProtKB=F7E1X7 F7E1X7 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000038197.1|UniProtKB=A0A5F8GHG2 A0A5F8GHG2 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000018415.4|UniProtKB=F6XUZ7 F6XUZ7 WNT5A PTHR12027:SF33 WNT RELATED PROTEIN WNT-5A G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;system development#GO:0048731;cell fate commitment#GO:0045165;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444;Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206 MONDO|Ensembl=ENSMODG00000024715.2|UniProtKB=F7FC06 F7FC06 PTHR23200:SF48 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000003509.3|UniProtKB=F7C831 F7C831 OR8D2 PTHR48018:SF173 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8D2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037725.1|UniProtKB=A0A5F8GXH4 A0A5F8GXH4 S100A3 PTHR11639:SF12 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A3 calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000011363.3|UniProtKB=F6T593 F6T593 OR51I2 PTHR26450:SF112 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51I2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016473.4|UniProtKB=F6ZDJ6 F6ZDJ6 THOC6 PTHR44411:SF1 THO COMPLEX SUBUNIT 6 HOMOLOG THO COMPLEX SUBUNIT 6 localization#GO:0051179;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transcription export complex#GO:0000346;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;THO complex#GO:0000347;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000014744.3|UniProtKB=F6YN88 F6YN88 LPO PTHR11475:SF67 OXIDASE/PEROXIDASE LACTOPEROXIDASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601 antibacterial humoral response#GO:0019731;response to external stimulus#GO:0009605;defense response#GO:0006952;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000037854.1|UniProtKB=A0A5F8H1C2 A0A5F8H1C2 KIF25 PTHR24115:SF421 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF25 microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774 cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 intracellular organelle#GO:0043229;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000001494.5|UniProtKB=F7F4N4 F7F4N4 STIL PTHR15128:SF0 TAL1 SCL INTERRUPTING LOCUS SCL-INTERRUPTING LOCUS PROTEIN protein localization to microtubule organizing center#GO:1905508;response to stimulus#GO:0050896;mitotic spindle organization#GO:0007052;signaling#GO:0023052;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cell surface receptor signaling pathway#GO:0007166;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;localization#GO:0051179;cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;smoothened signaling pathway#GO:0007224;mitotic cell cycle#GO:0000278;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;protein localization to centrosome#GO:0071539;cellular response to stimulus#GO:0051716;spindle organization#GO:0007051;intracellular protein localization#GO:0008104;mitotic cell cycle process#GO:1903047;protein localization to microtubule cytoskeleton#GO:0072698;biological regulation#GO:0065007;macromolecule localization#GO:0033036 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000005537.4|UniProtKB=A0A5F8HBP2 A0A5F8HBP2 ATP2B2 PTHR24093:SF377 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 2 ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662 chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;regulation of cytosolic calcium ion concentration#GO:0051480;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592 postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000010574.3|UniProtKB=F6YDH0 F6YDH0 EEF1A1 PTHR23115:SF222 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA 1-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412 translation factor#PC00223 MONDO|Ensembl=ENSMODG00000037858.1|UniProtKB=A0A5F8GN08 A0A5F8GN08 PTHR10986:SF16 39S RIBOSOMAL PROTEIN L20 LARGE RIBOSOMAL SUBUNIT PROTEIN BL20M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000005990.4|UniProtKB=F6SLB6 F6SLB6 ACBD3 PTHR22973:SF11 LD35087P GOLGI RESIDENT PROTEIN GCP60 protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;Golgi organization#GO:0007030;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000007679.4|UniProtKB=F7FNF3 F7FNF3 APAF1 PTHR22845:SF5 APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 FAS signaling pathway#P00020>Apaf1#P00597;Apoptosis signaling pathway#P00006>Apaf-1#P00301;Huntington disease#P00029>Apaf-1#P00768;p53 pathway#P00059>Apaf#G04703 MONDO|Ensembl=ENSMODG00000000003.4|UniProtKB=F7G5G1 F7G5G1 PRSS37 PTHR24271:SF61 KALLIKREIN-RELATED INACTIVE SERINE PROTEASE 37-RELATED serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;regulation of reproductive process#GO:2000241;biosynthetic process#GO:0009058;biological regulation#GO:0065007;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;acrosomal vesicle#GO:0001669 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000048410.1|UniProtKB=A0A5F8G3Y9 A0A5F8G3Y9 PTHR15224:SF1 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5 cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005 respiratory chain complex I#GO:0045271;transporter complex#GO:1990351;organelle membrane#GO:0031090;membrane#GO:0016020;oxidoreductase complex#GO:1990204;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000038456.1|UniProtKB=A0A5F8GWB1 A0A5F8GWB1 NDUFAF8 PTHR34561:SF1 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 8 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 8 cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000014427.4|UniProtKB=F7BGH7 F7BGH7 TENT5B PTHR12974:SF46 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5B catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566 biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of RNA stability#GO:0043487;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA stabilization#GO:0043489 MONDO|Ensembl=ENSMODG00000013227.4|UniProtKB=A0A5F8H7C3 A0A5F8H7C3 SLC6A2 PTHR11616:SF336 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NORADRENALINE TRANSPORTER solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;chloride transmembrane transporter activity#GO:0015108;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509 organic hydroxy compound transport#GO:0015850;monoatomic ion transport#GO:0006811;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;cellular localization#GO:0051641;trans-synaptic signaling#GO:0099537;signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;amino acid transport#GO:0006865;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter transport#GO:0006836;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;establishment of localization in cell#GO:0051649;synaptic transmission, dopaminergic#GO:0001963;cellular process#GO:0009987;synaptic signaling#GO:0099536;nitrogen compound transport#GO:0071705 plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell body#GO:0044297;axon#GO:0030424;presynaptic membrane#GO:0042734;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cell periphery#GO:0071944;presynapse#GO:0098793;neuron projection#GO:0043005;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>NET#P00064 MONDO|Ensembl=ENSMODG00000015091.3|UniProtKB=F7F3E3 F7F3E3 LOC100019251 PTHR22574:SF13 FAMILY NOT NAMED GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 1B MONDO|Ensembl=ENSMODG00000038489.1|UniProtKB=A0A5F8H6A3 A0A5F8H6A3 EPHX4 PTHR43329:SF2 EPOXIDE HYDROLASE EPOXIDE HYDROLASE 4 ether hydrolase activity#GO:0016803;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000027715.2|UniProtKB=K7E587 K7E587 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000002660.4|UniProtKB=F7DI42 F7DI42 DFFA PTHR12306:SF16 CELL DEATH ACTIVATOR CIDE DNAATION FACTOR SUBUNIT ALPHA lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;lipid transfer activity#GO:0120013 biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;negative regulation of apoptotic process#GO:0043066;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle fusion#GO:0048284;lipid storage#GO:0019915;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;cellular component organization or biogenesis#GO:0071840;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;cell death#GO:0008219;apoptotic process#GO:0006915;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;programmed cell death#GO:0012501;negative regulation of catabolic process#GO:0009895;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;lipid droplet organization#GO:0034389 chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811 MONDO|Ensembl=ENSMODG00000038439.1|UniProtKB=A0A5F8H012 A0A5F8H012 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000021581.2|UniProtKB=Q65CI6 Q65CI6 MT-ND3 PTHR11058:SF26 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3 primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;active transmembrane transporter activity#GO:0022804;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity, acting on NAD(P)H#GO:0016651;electron transfer activity#GO:0009055;NADH dehydrogenase activity#GO:0003954 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000003571.3|UniProtKB=F7G0R8 F7G0R8 PTHR11783:SF212 SULFOTRANSFERASE SULT SULFOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000006085.4|UniProtKB=F7FEI2 F7FEI2 METTL3 PTHR12829:SF7 N6-ADENOSINE-METHYLTRANSFERASE N(6)-ADENOSINE-METHYLTRANSFERASE CATALYTIC SUBUNIT METTL3 RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA modification#GO:0016556;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;RNA modification#GO:0009451;metabolic process#GO:0008152;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000000807.3|UniProtKB=A0A5F8HE24 A0A5F8HE24 TRA2A PTHR48034:SF14 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED TRANSFORMER-2 PROTEIN HOMOLOG ALPHA binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000024988.2|UniProtKB=F6U9K0 F6U9K0 PTHR23143:SF30 TRICHOHYALIN-RELATED COILED-COIL DOMAIN CONTAINING 70 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000043203.1|UniProtKB=A0A5F8H363 A0A5F8H363 TMEM250 PTHR48431:SF1 TRANSMEMBRANE PROTEIN 250 TRANSMEMBRANE PROTEIN 250 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000048426.1|UniProtKB=A0A5F8GPL4 A0A5F8GPL4 PTHR13718:SF4 RIBOSOMAL S SUBUNIT SMALL RIBOSOMAL SUBUNIT PROTEIN US5 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000009345.4|UniProtKB=F7GAM5 F7GAM5 ADAMTS2 PTHR13723:SF141 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 2 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152;external encapsulating structure organization#GO:0045229;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000017276.4|UniProtKB=F6T3J5 F6T3J5 FANCB PTHR28450:SF1 FANCONI ANEMIA GROUP B PROTEIN FANCONI ANEMIA GROUP B PROTEIN positive regulation of macromolecule metabolic process#GO:0010604;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;negative regulation of double-strand break repair via homologous recombination#GO:2000042;regulation of double-strand break repair via homologous recombination#GO:0010569;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;double-strand break repair via homologous recombination#GO:0000724;regulation of DNA metabolic process#GO:0051052;positive regulation of metabolic process#GO:0009893;regulation of cellular response to stress#GO:0080135;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA recombination#GO:0000018;cellular response to stress#GO:0033554;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;positive regulation of DNA repair#GO:0045739;negative regulation of DNA metabolic process#GO:0051053;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;DNA damage response#GO:0006974;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of double-strand break repair#GO:2000781;primary metabolic process#GO:0044238;negative regulation of DNA recombination#GO:0045910;positive regulation of DNA metabolic process#GO:0051054;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;regulation of double-strand break repair#GO:2000779;recombinational repair#GO:0000725 Fanconi anaemia nuclear complex#GO:0043240;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000024913.2|UniProtKB=F6SGI9 F6SGI9 PTHR16231:SF5 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 6 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;tumor necrosis factor-mediated signaling pathway#GO:0033209;cell communication#GO:0007154;response to peptide#GO:1901652;response to tumor necrosis factor#GO:0034612;cellular process#GO:0009987;signal transduction#GO:0007165;response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000002471.2|UniProtKB=A0A5F8H7E7 A0A5F8H7E7 LOC100019367 PTHR16105:SF2 RNA-BINDING REGION-CONTAINING PROTEIN 3 RNA-BINDING PROTEIN 41 MONDO|Ensembl=ENSMODG00000007019.3|UniProtKB=F6UFY5 F6UFY5 OR6S1 PTHR26454:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6S1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045413.1|UniProtKB=A0A5F8H8V4 A0A5F8H8V4 PTHR33166:SF1 GAG_P30 DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000051536.1|UniProtKB=A0A5F8GBD5 A0A5F8GBD5 CREBL2 PTHR21051:SF4 CAMP-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE 2 CAMP-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE 2 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000023690.2|UniProtKB=F6RBQ7 F6RBQ7 LOC100017553 PTHR11937:SF458 ACTIN ACTIN-85C-LIKE structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000000945.3|UniProtKB=F7F7V1 F7F7V1 FCRLB PTHR11481:SF94 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE B molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;immune system process#GO:0002376;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;immune response#GO:0006955;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000014111.4|UniProtKB=H9H6P1 H9H6P1 CLEC11A PTHR22799:SF1 TETRANECTIN-RELATED C-TYPE LECTIN DOMAIN FAMILY 11 MEMBER A signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 ossification#GO:0001503;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000012094.4|UniProtKB=F7G4N3 F7G4N3 NPRL2 PTHR12991:SF10 NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4 GATOR1 COMPLEX PROTEIN NPRL2 GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;cellular response to nutrient levels#GO:0031669;negative regulation of TORC1 signaling#GO:1904262;regulation of response to stimulus#GO:0048583;regulation of TORC1 signaling#GO:1903432;response to nutrient levels#GO:0031667;response to stress#GO:0006950;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;cellular response to amino acid starvation#GO:0034198;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;response to starvation#GO:0042594;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of TOR signaling#GO:0032007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;vacuolar membrane#GO:0005774;Seh1-associated complex#GO:0035859;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GTPase-activating protein#PC00257;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000012792.2|UniProtKB=A0A5F8HA45 A0A5F8HA45 TMED4 PTHR22811:SF38 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 4 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;cellular component organization#GO:0016043;Golgi organization#GO:0007030 endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 membrane traffic protein#PC00150;vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000051369.1|UniProtKB=A0A5F8GRT3 A0A5F8GRT3 FETUB PTHR13814:SF10 FETUIN FETUIN-B enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 cellular process#GO:0009987;single fertilization#GO:0007338;fertilization#GO:0009566;reproductive process#GO:0022414;cell recognition#GO:0008037;sexual reproduction#GO:0019953;sperm-egg recognition#GO:0035036;cell-cell recognition#GO:0009988;binding of sperm to zona pellucida#GO:0007339 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000014019.4|UniProtKB=A0A5F8H585 A0A5F8H585 PTHR11486:SF77 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 13 ion channel regulator activity#GO:0099106;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;fibroblast growth factor receptor binding#GO:0005104;transporter regulator activity#GO:0141108;signaling receptor binding#GO:0005102;binding#GO:0005488;channel regulator activity#GO:0016247;molecular function activator activity#GO:0140677;protein binding#GO:0005515 multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of cell migration#GO:0030334;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000017591.4|UniProtKB=A0A5F8H786 A0A5F8H786 NOTCH1 PTHR12916:SF16 CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2 NOTCH HOMOLOG 2 N-TERMINAL-LIKE PROTEIN A-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;Notch signaling pathway#GO:0007219;cell communication#GO:0007154 oxidoreductase#PC00176;oxidase#PC00175 MONDO|Ensembl=ENSMODG00000043251.1|UniProtKB=A0A5F8H8R1 A0A5F8H8R1 UBALD2 PTHR31993:SF6 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000017822.4|UniProtKB=F6ZXC8 F6ZXC8 MAPDA PTHR11409:SF42 ADENOSINE DEAMINASE N6-METHYL-AMP DEAMINASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;adenosine deaminase activity#GO:0004000 carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule catabolic process#GO:0034656;primary metabolic process#GO:0044238;nucleoside catabolic process#GO:0009164;purine nucleoside metabolic process#GO:0042278;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;adenosine metabolic process#GO:0046085;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;nucleobase metabolic process#GO:0009112;purine-containing compound catabolic process#GO:0072523;carbohydrate derivative biosynthetic process#GO:1901137;small molecule biosynthetic process#GO:0044283;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 deaminase#PC00088 Adenine and hypoxanthine salvage pathway#P02723>Adenosine deaminase#P02811;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine deaminase#P02807 MONDO|Ensembl=ENSMODG00000001352.4|UniProtKB=A0A5F8GVB2 A0A5F8GVB2 ROR1 PTHR24416:SF134 TYROSINE-PROTEIN KINASE RECEPTOR INACTIVE TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR1 catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;Wnt-protein binding#GO:0017147;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 signaling receptor complex#GO:0043235;axon#GO:0030424;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003603.4|UniProtKB=F7C6L8 F7C6L8 PTHR31477:SF1 CENTROSOMAL PROTEIN OF 44 KDA CENTROSOMAL PROTEIN OF 44 KDA microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;centriole replication#GO:0007099;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000019054.2|UniProtKB=F6RBR7 F6RBR7 ACTRT2 PTHR11937:SF38 ACTIN ACTIN-RELATED PROTEIN T2 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000000176.3|UniProtKB=F6TGD0 F6TGD0 BRAT1 PTHR21331:SF2 BRCA1-ASSOCIATED ATM ACTIVATOR 1 INTEGRATOR COMPLEX ASSEMBLY FACTOR BRAT1 response to stress#GO:0006950;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000005328.5|UniProtKB=A0A5F8H7A6 A0A5F8H7A6 IL17RC PTHR15583:SF12 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR C signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;response to cytokine#GO:0034097;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to peptide#GO:1901652;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007310.4|UniProtKB=A0A5F8H499 A0A5F8H499 LOC103093231 PTHR12378:SF41 DESUMOYLATING ISOPEPTIDASE PALMITOYL-PROTEIN HYDROLASE deubiquitinase activity#GO:0101005;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000036994.1|UniProtKB=A0A5F8GDR7 A0A5F8GDR7 MYORG PTHR43053:SF8 GLYCOSIDASE FAMILY 31 ALPHA-GALACTOSIDASE MYORG tissue development#GO:0009888;skeletal muscle tissue development#GO:0007519;cellular process#GO:0009987;striated muscle cell differentiation#GO:0051146;animal organ development#GO:0048513;cellular developmental process#GO:0048869;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;muscle organ development#GO:0007517;cell development#GO:0048468;muscle structure development#GO:0061061;cell differentiation#GO:0030154;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108 metabolite interconversion enzyme#PC00262;glucosidase#PC00108;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000020040.3|UniProtKB=F6ZH84 F6ZH84 LOC100023135 PTHR26452:SF830 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5T7 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000022849.2|UniProtKB=F6PJC6 F6PJC6 LOC100027035 PTHR22750:SF25 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 12-LIKE G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000004423.4|UniProtKB=F6SD01 F6SD01 MARF1 PTHR14379:SF93 LIMKAIN B LKAP MEIOSIS REGULATOR AND MRNA STABILITY FACTOR 1 protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000013016.4|UniProtKB=A0A5F8HCE2 A0A5F8HCE2 DDHD1 PTHR23509:SF32 PA-PL1 PHOSPHOLIPASE FAMILY PHOSPHOLIPASE DDHD1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;lipase activity#GO:0016298;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000008306.3|UniProtKB=F7FGZ0 F7FGZ0 FOXJ1 PTHR46805:SF1 FORKHEAD BOX PROTEIN J1 FORKHEAD BOX PROTEIN J1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000019490.4|UniProtKB=F6WA14 F6WA14 BCL2L1 PTHR11256:SF12 BCL-2 RELATED BCL-2-LIKE PROTEIN 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;response to stress#GO:0006950;organelle organization#GO:0006996;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway#GO:0097193;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;release of cytochrome c from mitochondria#GO:0001836;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;apoptotic signaling pathway#GO:0097190;positive regulation of cellular process#GO:0048522;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794 mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 CCKR signaling map#P06959>BCL2L1#P07117;Apoptosis signaling pathway#P00006>Bcl-xL#P00257;Apoptosis signaling pathway#P00006>Bcl-xS#P00323 MONDO|Ensembl=ENSMODG00000001360.3|UniProtKB=F7FW03 F7FW03 FAM78B PTHR31655:SF0 PROTEIN FAM78A PROTEIN FAM78B MONDO|Ensembl=ENSMODG00000013964.4|UniProtKB=F6R731 F6R731 PTH1R PTHR45620:SF27 PDF RECEPTOR-LIKE PROTEIN-RELATED PARATHYROID HORMONE_PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;binding#GO:0005488;identical protein binding#GO:0042802;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 cell communication#GO:0007154;inorganic ion homeostasis#GO:0098771;G protein-coupled receptor signaling pathway#GO:0007186;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;intracellular monoatomic ion homeostasis#GO:0006873;intracellular calcium ion homeostasis#GO:0006874;system process#GO:0003008;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;renal absorption#GO:0070293;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;renal system process#GO:0003014;monoatomic ion homeostasis#GO:0050801 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008464.4|UniProtKB=F7GES9 F7GES9 ACAD9 PTHR43884:SF9 ACYL-COA DEHYDROGENASE COMPLEX I ASSEMBLY FACTOR ACAD9, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000003686.2|UniProtKB=F7FAJ7 F7FAJ7 UBE2R2 PTHR24067:SF148 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 R2 aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 protein K48-linked ubiquitination#GO:0070936;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000016347.2|UniProtKB=F7F794 F7F794 PARD6B PTHR14102:SF4 PAR-6-RELATED PARTITIONING DEFECTIVE 6 HOMOLOG BETA protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cell junction organization#GO:0034330;cell-cell junction organization#GO:0045216;establishment or maintenance of cell polarity#GO:0007163;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cell-cell junction maintenance#GO:0045217;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 apical plasma membrane#GO:0016324;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transferase complex#GO:1990234;apical part of cell#GO:0045177;protein kinase complex#GO:1902911 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000027637.2|UniProtKB=H9H7P6 H9H7P6 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000017660.4|UniProtKB=F6YJA3 F6YJA3 DUOX1 PTHR11972:SF75 NADPH OXIDASE DUAL OXIDASE 1 catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 response to stimulus#GO:0050896;superoxide metabolic process#GO:0006801;defense response#GO:0006952;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;response to stress#GO:0006950;cellular process#GO:0009987 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494 oxidase#PC00175;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000013426.4|UniProtKB=F7EDI1 F7EDI1 PTHR24412:SF428 KELCH PROTEIN KELCH-LIKE PROTEIN 6 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006308.4|UniProtKB=F7BRI2 F7BRI2 SH3PXD2B PTHR15706:SF26 SH3 MULTIPLE DOMAIN SH3 AND PX DOMAIN-CONTAINING PROTEIN 2B enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;superoxide metabolic process#GO:0006801 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000024955.2|UniProtKB=F6UTJ7 F6UTJ7 LOC100017588 PTHR11165:SF189 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000003092.4|UniProtKB=F6PIX2 F6PIX2 TMEM252 PTHR35682:SF1 TRANSMEMBRANE PROTEIN 252 TRANSMEMBRANE PROTEIN 252 MONDO|Ensembl=ENSMODG00000017328.4|UniProtKB=F6WWG2 F6WWG2 TLR8 PTHR47410:SF1 TOLL-LIKE RECEPTOR 7-RELATED TOLL-LIKE RECEPTOR 8 molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023 regulation of macromolecule metabolic process#GO:0060255;positive regulation of cytokine production#GO:0001819;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;response to virus#GO:0009615;intracellular signal transduction#GO:0035556;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;positive regulation of response to stimulus#GO:0048584;canonical NF-kappaB signal transduction#GO:0007249;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of cytokine production#GO:0001817;activation of innate immune response#GO:0002218;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of gene expression#GO:0010628;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;regulation of gene expression#GO:0010468;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;toll-like receptor signaling pathway#GO:0002224;defense response to virus#GO:0051607;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;immune response-regulating signaling pathway#GO:0002764;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;immune system process#GO:0002376;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;intracellular signaling cassette#GO:0141124;regulation of multicellular organismal process#GO:0051239;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR#P01346 MONDO|Ensembl=ENSMODG00000001809.3|UniProtKB=F6T5H4 F6T5H4 LOC100012494 PTHR11504:SF1 CYTOCHROME C OXIDASE POLYPEPTIDE VIA CYTOCHROME C OXIDASE SUBUNIT 6A2, MITOCHONDRIAL enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;transporter complex#GO:1990351;catalytic complex#GO:1902494 oxidase#PC00175 MONDO|Ensembl=ENSMODG00000001661.4|UniProtKB=F6SRC7 F6SRC7 RFX4 PTHR12619:SF31 RFX TRANSCRIPTION FACTOR FAMILY TRANSCRIPTION FACTOR RFX4 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000049425.1|UniProtKB=A0A5F8GUH7 A0A5F8GUH7 JPT1 PTHR34930:SF4 GEO05313P1 JUPITER MICROTUBULE ASSOCIATED HOMOLOG 1 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000049900.1|UniProtKB=A0A5F8GPH3 A0A5F8GPH3 CBLL1 PTHR13480:SF0 E3 UBIQUITIN-PROTEIN LIGASE HAKAI-RELATED E3 UBIQUITIN-PROTEIN LIGASE HAKAI catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000003980.4|UniProtKB=F6Y317 F6Y317 PTHR43184:SF9 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A2 organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;phosphate transmembrane transporter activity#GO:0005315;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;transport#GO:0006810;organophosphate ester transport#GO:0015748;phosphate ion transport#GO:0006817;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000002050.4|UniProtKB=F6QBX8 F6QBX8 FAM83A PTHR16181:SF34 PROTEIN FAM83A-RELATED PROTEIN FAM83A protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 response to stimulus#GO:0050896;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166 MONDO|Ensembl=ENSMODG00000018122.5|UniProtKB=F6WMF3 F6WMF3 POU3F2 PTHR11636:SF115 POU DOMAIN POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000038735.1|UniProtKB=A0A5F8GSU1 A0A5F8GSU1 APH1B PTHR12889:SF1 GAMMA-SECRETASE SUBUNIT APH-1 GAMMA-SECRETASE SUBUNIT APH-1B protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cell communication#GO:0007154;protein metabolic process#GO:0019538;proteolysis#GO:0006508;biosynthetic process#GO:0009058;biological regulation#GO:0065007;gene expression#GO:0010467;protein maturation#GO:0051604;signal transduction#GO:0007165;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152 catalytic complex#GO:1902494;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 protein modifying enzyme#PC00260;protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>Aph-1#P00091;Notch signaling pathway#P00045>Aph-1#P01109;Alzheimer disease-presenilin pathway#P00004>Aph-1#P00170 MONDO|Ensembl=ENSMODG00000006856.4|UniProtKB=F6Q7I9 F6Q7I9 AUTS2 PTHR14429:SF5 FIBROSIN FAMILY MEMBER AUTISM SUSCEPTIBILITY GENE 2 PROTEIN MONDO|Ensembl=ENSMODG00000013788.4|UniProtKB=F6TEV9 F6TEV9 PLD4 PTHR10185:SF8 PHOSPHOLIPASE D - RELATED 5'-3' EXONUCLEASE PLD4 transport#GO:0006810;phagocytosis#GO:0006909;endocytosis#GO:0006897;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000018879.4|UniProtKB=A0A5F8GSG7 A0A5F8GSG7 PTHR46349:SF4 CINGULIN-LIKE PROTEIN 1-RELATED CINGULIN protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 apical junction complex#GO:0043296;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;tight junction#GO:0070160;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000006262.4|UniProtKB=F7FE13 F7FE13 SNX31 PTHR12431:SF15 SORTING NEXIN 17 AND 27 SORTING NEXIN-31 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 metabolic process#GO:0008152;intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810;macromolecule metabolic process#GO:0043170;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000016025.4|UniProtKB=F7EFT6 F7EFT6 USP48 PTHR24006:SF722 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 48 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000003245.4|UniProtKB=F6THE1 F6THE1 GMPR2 PTHR43170:SF4 GMP REDUCTASE GMP REDUCTASE 2 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000028639.2|UniProtKB=K7E3S0 K7E3S0 PTHR35826:SF5 PROTEIN ATP6V1FNB-LIKE GENE 45521-RELATED MONDO|Ensembl=ENSMODG00000013042.4|UniProtKB=A0A5F8GVL0 A0A5F8GVL0 PTHR45883:SF2 HSC70-INTERACTING PROTEIN HSC70-INTERACTING PROTEIN protein-folding chaperone binding#GO:0051087;binding#GO:0005488;heat shock protein binding#GO:0031072;protein binding#GO:0005515;Hsp70 protein binding#GO:0030544 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 MONDO|Ensembl=ENSMODG00000008678.5|UniProtKB=F6PFU0 F6PFU0 HAND1 PTHR23349:SF3 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST HEART- AND NEURAL CREST DERIVATIVES-EXPRESSED PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;heart development#GO:0007507;multicellular organismal process#GO:0032501 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000016240.2|UniProtKB=F7C2J0 F7C2J0 LOC100012979 PTHR26453:SF562 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13F1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045957.1|UniProtKB=A0A5F8G9T9 A0A5F8G9T9 monDomV1R1212 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003037.4|UniProtKB=F6Q138 F6Q138 HPF1 PTHR13386:SF1 HISTONE PARYLATION FACTOR 1 HISTONE PARYLATION FACTOR 1 protein binding#GO:0005515;histone binding#GO:0042393;carbohydrate derivative binding#GO:0097367;binding#GO:0005488 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;chromatin remodeling#GO:0006338;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000012548.4|UniProtKB=F6PM00 F6PM00 PTHR18952:SF91 CARBONIC ANHYDRASE CARBONIC ANHYDRASE-RELATED PROTEIN 10 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000012685.3|UniProtKB=F6VG35 F6VG35 ETFBKMT PTHR43648:SF3 ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279 regulation of lipid metabolic process#GO:0019216;negative regulation of cellular process#GO:0048523;negative regulation of catabolic process#GO:0009895;regulation of catabolic process#GO:0009894;negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of lipid catabolic process#GO:0050994;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892 methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000018834.3|UniProtKB=F7GKB3 F7GKB3 TFAP2D PTHR10812:SF5 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-DELTA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000039255.1|UniProtKB=A0A5F8GPW4 A0A5F8GPW4 NDUFC2 PTHR13099:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B14.5B NADH DEHYDROGENASE [UBIQUINONE] 1 SUBUNIT C2-RELATED transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000006707.3|UniProtKB=F7DGV3 F7DGV3 ANAPC1 PTHR12827:SF3 MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER ANAPHASE-PROMOTING COMPLEX SUBUNIT 1 regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein K11-linked ubiquitination#GO:0070979;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;protein modification by small protein conjugation or removal#GO:0070647;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;regulation of chromosome segregation#GO:0051983;metaphase/anaphase transition of cell cycle#GO:0044784;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cell cycle#GO:0007049;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;mitotic cell cycle phase transition#GO:0044772;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;regulation of chromosome organization#GO:0033044;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000021232.2|UniProtKB=A0A5F8H6F9 A0A5F8H6F9 RNF7 PTHR11210:SF60 RING BOX RING-BOX PROTEIN 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul5-RING ubiquitin ligase complex#GO:0031466;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000007275.4|UniProtKB=K7E291 K7E291 LSM3 PTHR13110:SF0 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3 LSM3 HOMOLOG, U6 SMALL NUCLEAR RNA AND MRNA DEGRADATION ASSOCIATED binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;P-body#GO:0000932;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;U4/U6 x U5 tri-snRNP complex#GO:0046540;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000036699.1|UniProtKB=A0A5F8G383 A0A5F8G383 PTHR23267:SF486 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 14_DELTA VARIABLE 4 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000037007.1|UniProtKB=A0A5F8GLZ2 A0A5F8GLZ2 CCR6 PTHR10489:SF611 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 6 protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine receptor activity#GO:0004896 immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;cellular response to stimulus#GO:0051716;regulation of leukocyte migration#GO:0002685;regulation of immune system process#GO:0002682;cell motility#GO:0048870;regulation of cellular process#GO:0050794;locomotion#GO:0040011;chemotaxis#GO:0006935;cell communication#GO:0007154;regulation of cell motility#GO:2000145;positive regulation of chemotaxis#GO:0050921;cell chemotaxis#GO:0060326;intracellular signal transduction#GO:0035556;positive regulation of immune system process#GO:0002684;lymphocyte migration#GO:0072676;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to chemical#GO:0042221;taxis#GO:0042330;regulation of response to external stimulus#GO:0032101;intracellular signaling cassette#GO:0141124;positive regulation of response to external stimulus#GO:0032103;positive regulation of cell motility#GO:2000147;regulation of chemotaxis#GO:0050920;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;mononuclear cell migration#GO:0071674;regulation of biological quality#GO:0065008 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000009644.3|UniProtKB=F6QTC3 F6QTC3 CASQ1 PTHR10033:SF14 CALSEQUESTRIN CALSEQUESTRIN-1 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;molecular sequestering activity#GO:0140313;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;intracellular signaling cassette#GO:0141124;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;regulation of system process#GO:0044057;regulation of monoatomic cation transmembrane transport#GO:1904062;calcium-mediated signaling#GO:0019722;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762;regulation of muscle system process#GO:0090257;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;response to stimulus#GO:0050896;regulation of muscle contraction#GO:0006937;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;Z disc#GO:0030018;sarcoplasmic reticulum#GO:0016529;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;endoplasmic reticulum#GO:0005783;I band#GO:0031674;membraneless organelle#GO:0043228;sarcomere#GO:0030017;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;sarcoplasm#GO:0016528;intracellular organelle lumen#GO:0070013;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000009016.4|UniProtKB=A0A5F8H4A3 A0A5F8H4A3 FAM3A PTHR14592:SF11 UNCHARACTERIZED FAM3 PROTEIN FAM3A cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000024474.1|UniProtKB=F7GFL1 F7GFL1 PTHR23291:SF133 BAX INHIBITOR-RELATED BAX INHIBITOR 1 enzyme regulator activity#GO:0030234;calcium ion transmembrane transporter activity#GO:0015085;molecular function inhibitor activity#GO:0140678;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;enzyme inhibitor activity#GO:0004857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772;metal ion transmembrane transporter activity#GO:0046873 negative regulation of apoptotic signaling pathway#GO:2001234;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of signaling#GO:0023057;cellular response to unfolded protein#GO:0034620;negative regulation of cell communication#GO:0010648;response to unfolded protein#GO:0006986;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;response to topologically incorrect protein#GO:0035966;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;response to stress#GO:0006950;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 ion channel#PC00133;transporter#PC00227 Apoptosis signaling pathway#P00006>Bi1#P00277 MONDO|Ensembl=ENSMODG00000049873.1|UniProtKB=A0A5F8HF41 A0A5F8HF41 PTHR15706:SF10 SH3 MULTIPLE DOMAIN NADPH OXIDASE ORGANIZER 1 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;superoxide metabolic process#GO:0006801 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006487.4|UniProtKB=A0A5F8GQR6 A0A5F8GQR6 HCN2 PTHR45689:SF11 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 2 potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;potassium ion transport#GO:0006813;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220 monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000049851.1|UniProtKB=A0A5F8GXT0 A0A5F8GXT0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000005592.4|UniProtKB=F7DJX3 F7DJX3 B3GAT1 PTHR10896:SF21 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 1 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glucuronosyltransferase activity#GO:0015020 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;chondroitin sulfate proteoglycan metabolic process#GO:0050654;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000006732.3|UniProtKB=F7CX16 F7CX16 CIAO2B PTHR12377:SF0 CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000004737.4|UniProtKB=F6Y173 F6Y173 PTHR20437:SF0 TUMOR NECROSIS FACTOR RECEPTOR SUBFAMILY MEMBER 13/17 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 17 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040713.1|UniProtKB=H9H8H7 H9H8H7 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000011829.4|UniProtKB=A0A5F8GY12 A0A5F8GY12 MYO1B PTHR13140:SF277 MYOSIN UNCONVENTIONAL MYOSIN-IB isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;microfilament motor activity#GO:0000146 sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;nervous system process#GO:0050877;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cellular component organization#GO:0016043;sensory perception of sound#GO:0007605;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;transport#GO:0006810;actin filament organization#GO:0007015;system process#GO:0003008;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;actin filament-based movement#GO:0030048;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501 actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;brush border#GO:0005903;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;membraneless organelle#GO:0043228 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000040397.1|UniProtKB=F6RTJ8 F6RTJ8 LOC130459055 PTHR24225:SF0 CHEMOTACTIC RECEPTOR N-FORMYL PEPTIDE RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 immune response-activating signaling pathway#GO:0002757;positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000009509.4|UniProtKB=F7FPW5 F7FPW5 PTHR11346:SF98 GALECTIN GALECTIN-RELATED PROTEIN carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000008385.4|UniProtKB=F7CDL0 F7CDL0 CHEK2 PTHR44167:SF39 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED SERINE_THREONINE-PROTEIN KINASE CHK2 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;DNA integrity checkpoint signaling#GO:0031570;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;mitotic cell cycle process#GO:1903047;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>Chk2#P01484 MONDO|Ensembl=ENSMODG00000051558.1|UniProtKB=A0A5F8GIJ0 A0A5F8GIJ0 FAM241A PTHR33690:SF1 DUF4605 DOMAIN-CONTAINING PROTEIN FAMILY WITH SEQUENCE SIMILARITY 241 MEMBER A intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000011167.3|UniProtKB=F6ZZT4 F6ZZT4 LOC100021223 PTHR26450:SF1 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR FAMILY 51 SUBFAMILY AB MEMBER 3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023140.3|UniProtKB=F7D8X5 F7D8X5 PTHR24376:SF85 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 600-RELATED regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000010127.4|UniProtKB=F6WN34 F6WN34 VPS53 PTHR12820:SF0 VACUOLAR SORTING PROTEIN 53 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000006340.2|UniProtKB=F7AG57 F7AG57 VRTN PTHR16081:SF0 VERTNIN VERTNIN regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000004429.4|UniProtKB=F6SCG6 F6SCG6 CHPF2 PTHR12369:SF14 CHONDROITIN SYNTHASE CHONDROITIN POLYMERIZING FACTOR 2, NON-CATALYTIC SUBUNIT protein complex scaffold activity#GO:0140378;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;structural molecule activity#GO:0005198;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000021509.5|UniProtKB=F6VD07 F6VD07 ZNF521 PTHR24376:SF84 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 521 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000014970.5|UniProtKB=F7CGN1 F7CGN1 XIAP PTHR10044:SF115 INHIBITOR OF APOPTOSIS E3 UBIQUITIN-PROTEIN LIGASE XIAP acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme regulator activity#GO:0030234;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772 regulation of apoptotic process#GO:0042981;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of protein metabolic process#GO:0051246;positive regulation of protein ubiquitination#GO:0031398;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of macromolecule metabolic process#GO:0010604;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell cycle#GO:0051726;regulation of protein ubiquitination#GO:0031396;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of protein modification process#GO:0031399;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 Apoptosis signaling pathway#P00006>XIAP#P00304 MONDO|Ensembl=ENSMODG00000040776.1|UniProtKB=A0A5F8HBT6 A0A5F8HBT6 LOC100617288 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010926.4|UniProtKB=A0A5F8HHC4 A0A5F8HHC4 DAPK2 PTHR24342:SF15 SERINE/THREONINE-PROTEIN KINASE 17 DEATH-ASSOCIATED PROTEIN KINASE 2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;signaling#GO:0023052 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000029138.2|UniProtKB=K7E171 K7E171 LOC100027399 PTHR24100:SF159 BUTYROPHILIN ICOS LIGAND signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;immune system process#GO:0002376;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000017185.3|UniProtKB=F6XXS8 F6XXS8 UBE2Q1 PTHR24068:SF56 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 Q1 aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000019573.3|UniProtKB=F6R853 F6R853 ABHD2 PTHR10794:SF45 ABHYDROLASE DOMAIN-CONTAINING PROTEIN MONOACYLGLYCEROL LIPASE ABHD2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 sexual reproduction#GO:0019953;spermatid development#GO:0007286;response to steroid hormone#GO:0048545;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;anatomical structure maturation#GO:0071695;steroid hormone receptor signaling pathway#GO:0043401;germ cell development#GO:0007281;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;neutral lipid catabolic process#GO:0046461;fatty acid metabolic process#GO:0006631;acylglycerol metabolic process#GO:0006639;cell maturation#GO:0048469;monocarboxylic acid biosynthetic process#GO:0072330;biosynthetic process#GO:0009058;biological regulation#GO:0065007;developmental maturation#GO:0021700;lipid biosynthetic process#GO:0008610;monocarboxylic acid catabolic process#GO:0072329;cellular response to chemical stimulus#GO:0070887;fatty acid catabolic process#GO:0009062;regulation of biological process#GO:0050789;monocarboxylic acid metabolic process#GO:0032787;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;small molecule catabolic process#GO:0044282;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;cellular response to steroid hormone stimulus#GO:0071383;signal transduction#GO:0007165;lipid catabolic process#GO:0016042;cellular process#GO:0009987;cellular response to lipid#GO:0071396;cell communication#GO:0007154;carboxylic acid biosynthetic process#GO:0046394;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;catabolic process#GO:0009056;spermatogenesis#GO:0007283;developmental process#GO:0032502;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;neutral lipid metabolic process#GO:0006638;cellular developmental process#GO:0048869;carboxylic acid catabolic process#GO:0046395;fatty acid biosynthetic process#GO:0006633;male gamete generation#GO:0048232;oxoacid metabolic process#GO:0043436;glycerolipid catabolic process#GO:0046503;spermatid differentiation#GO:0048515;hormone-mediated signaling pathway#GO:0009755;response to endogenous stimulus#GO:0009719;carboxylic acid metabolic process#GO:0019752;signaling#GO:0023052;glycerolipid metabolic process#GO:0046486;cellular response to endogenous stimulus#GO:0071495;small molecule metabolic process#GO:0044281;cell differentiation#GO:0030154;gamete generation#GO:0007276;metabolic process#GO:0008152;acylglycerol catabolic process#GO:0046464;response to hormone#GO:0009725;sperm capacitation#GO:0048240;response to chemical#GO:0042221;response to lipid#GO:0033993 membrane#GO:0016020;cell periphery#GO:0071944;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cilium#GO:0005929;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227 protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000021109.3|UniProtKB=F6U2Y1 F6U2Y1 PTHR21255:SF20 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 3 binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000022940.2|UniProtKB=F6PYV2 F6PYV2 PTHR26450:SF35 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037599.1|UniProtKB=A0A5F8GLK6 A0A5F8GLK6 NKG7 PTHR10671:SF34 EPITHELIAL MEMBRANE PROTEIN-RELATED PROTEIN NKG7 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000005708.4|UniProtKB=F6U4E3 F6U4E3 PELP1 PTHR34105:SF1 PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1 PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1 metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000015131.4|UniProtKB=F7D069 F7D069 MPHOSPH6 PTHR13582:SF0 M-PHASE PHOSPHOPROTEIN 6 M-PHASE PHOSPHOPROTEIN 6 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000041298.1|UniProtKB=A0A5F8G2W8 A0A5F8G2W8 LOC103099706 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002258.4|UniProtKB=F7CWE2 F7CWE2 TMEM192 PTHR31592:SF1 TRANSMEMBRANE PROTEIN 192 TRANSMEMBRANE PROTEIN 192 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;endomembrane system#GO:0012505;late endosome#GO:0005770;lysosomal membrane#GO:0005765;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323 MONDO|Ensembl=ENSMODG00000004674.3|UniProtKB=F6U708 F6U708 DOK3 PTHR21258:SF42 DOCKING PROTEIN RELATED DOCKING PROTEIN 3 Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dok-R#P00180 MONDO|Ensembl=ENSMODG00000037046.1|UniProtKB=A0A5F8H7G3 A0A5F8H7G3 PTHR11434:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT ND4L NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4L protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000038510.1|UniProtKB=A0A5F8H1E3 A0A5F8H1E3 PTHR35252:SF1 RETINITIS PIGMENTOSA 9 PROTEIN RETINITIS PIGMENTOSA 9 PROTEIN MONDO|Ensembl=ENSMODG00000017954.3|UniProtKB=F7E348 F7E348 GJB4 PTHR11984:SF30 CONNEXIN GAP JUNCTION BETA-4 PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267 cell communication#GO:0007154;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of biological process#GO:0050789;cellular process#GO:0009987 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;anchoring junction#GO:0070161;cell junction#GO:0030054 gap junction#PC00105;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000008878.3|UniProtKB=A0A5F8GTZ7 A0A5F8GTZ7 MSRA PTHR42799:SF2 MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;reductase#PC00198 MONDO|Ensembl=ENSMODG00000024142.2|UniProtKB=F6UJR0 F6UJR0 PTHR22977:SF1 COX ASSEMBLY MITOCHONDRIAL PROTEIN COX ASSEMBLY MITOCHONDRIAL PROTEIN 2 HOMOLOG intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000018364.3|UniProtKB=F6PPU5 F6PPU5 MRAP2 PTHR28675:SF1 MELANOCORTIN-2 RECEPTOR ACCESSORY PROTEIN 2 MELANOCORTIN-2 RECEPTOR ACCESSORY PROTEIN 2 protein binding#GO:0005515;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;binding#GO:0005488;neuropeptide receptor binding#GO:0071855;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664 regulation of signaling#GO:0023051;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;regulation of biological process#GO:0050789;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000048664.1|UniProtKB=A0A5F8HK56 A0A5F8HK56 SMIM5 PTHR37344:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 5 SMALL INTEGRAL MEMBRANE PROTEIN 5 MONDO|Ensembl=ENSMODG00000027985.2|UniProtKB=K7E239 K7E239 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010895.4|UniProtKB=F7FJ47 F7FJ47 EFNB1 PTHR11304:SF17 EPHRIN EPHRIN-B1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;axon development#GO:0061564;axon guidance#GO:0007411;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167 cell junction#GO:0030054;synaptic membrane#GO:0097060;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020 intercellular signal molecule#PC00207;membrane-bound signaling molecule#PC00152 Angiogenesis#P00005>Eph#P00239 MONDO|Ensembl=ENSMODG00000002580.4|UniProtKB=F6Z8L4 F6Z8L4 PTHR10880:SF48 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000016717.3|UniProtKB=F7CHY4 F7CHY4 KIN PTHR12805:SF0 KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG DNA_RNA-BINDING PROTEIN KIN17 binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677 response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000051167.1|UniProtKB=A0A5F8HG73 A0A5F8HG73 PTHR21193:SF3 OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1 OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000008165.4|UniProtKB=F7EL05 F7EL05 MNS1 PTHR19265:SF0 MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1 MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1 cilium organization#GO:0044782;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000050373.1|UniProtKB=A0A5F8GYB3 A0A5F8GYB3 PTHR16317:SF1 INTEGRIN ALPHA REPEAT DOMAIN-CONTAINING KICSTOR COMPLEX PROTEIN ITFG2 cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to nutrient levels#GO:0031667;response to stress#GO:0006950;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;negative regulation of response to stimulus#GO:0048585;cellular response to nutrient levels#GO:0031669;negative regulation of TORC1 signaling#GO:1904262;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 protein-containing complex#GO:0032991 integrin#PC00126 MONDO|Ensembl=ENSMODG00000015390.4|UniProtKB=F6TKQ2 F6TKQ2 FEZ2 PTHR12394:SF11 ZYGIN FASCICULATION AND ELONGATION PROTEIN ZETA-2 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;neuron projection#GO:0043005;axon#GO:0030424 MONDO|Ensembl=ENSMODG00000014037.3|UniProtKB=F6UQJ4 F6UQJ4 KATNB1 PTHR19845:SF0 KATANIN P80 SUBUNIT KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1 protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;supramolecular fiber organization#GO:0097435;cellular component disassembly#GO:0022411;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;protein depolymerization#GO:0051261;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;microtubule depolymerization#GO:0007019 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000036558.1|UniProtKB=F7BT19 F7BT19 monDomV1R1225 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000042212.1|UniProtKB=A0A5F8GDY5 A0A5F8GDY5 TAFA5 PTHR31878:SF0 CHEMOKINE-LIKE PROTEIN TAFA-5-RELATED CHEMOKINE-LIKE PROTEIN TAFA-5 binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chemokine#PC00074;cytokine#PC00083 MONDO|Ensembl=ENSMODG00000008003.2|UniProtKB=F7CLJ7 F7CLJ7 TMEM179B PTHR31056:SF1 TRANSMEMBRANE PROTEIN 179B TRANSMEMBRANE PROTEIN 179B MONDO|Ensembl=ENSMODG00000028507.2|UniProtKB=K7E6A8 K7E6A8 PTHR46890:SF56 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED OS06G0484800 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016325.3|UniProtKB=F7FL45 F7FL45 PTHR24098:SF14 OUTER SEGMENT 5 TRIPARTITE MOTIF-CONTAINING PROTEIN 59 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intraciliary transport particle#GO:0030990;intraciliary transport particle B#GO:0030992;cilium#GO:0005929;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000002643.4|UniProtKB=F7DIE6 F7DIE6 PEX14 PTHR23058:SF0 PEROXISOMAL MEMBRANE PROTEIN PEX14 PEROXISOMAL MEMBRANE PROTEIN PEX14 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein transport#GO:0015031;peroxisomal transport#GO:0043574;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;peroxisome organization#GO:0007031;protein import into peroxisome matrix#GO:0016558;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;organelle organization#GO:0006996 membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000004341.4|UniProtKB=F6X603 F6X603 PTHR31259:SF3 ENDOSOME-ASSOCIATED TRAFFICKING REGULATOR 1 ENDOSOME-ASSOCIATED-TRAFFICKING REGULATOR 1 regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465 centrosome#GO:0005813;recycling endosome#GO:0055037;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;midbody#GO:0030496;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000008518.4|UniProtKB=F7FFN6 F7FFN6 MYCT1 PTHR14869:SF0 MYC TARGET PROTEIN 1 MYC TARGET PROTEIN 1 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000000809.3|UniProtKB=F6S9S9 F6S9S9 MAP2K2 PTHR47448:SF3 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000042119.1|UniProtKB=A0A5F8GRG0 A0A5F8GRG0 SDC4 PTHR10915:SF3 SYNDECAN SYNDECAN-4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of organelle assembly#GO:1902115;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087 anchoring junction#GO:0070161;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell junction#GO:0030054 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003368.4|UniProtKB=F7FH55 F7FH55 IRF9 PTHR11949:SF26 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 9 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000001378.4|UniProtKB=F7FJB7 F7FJB7 SLA2 PTHR46037:SF7 PROTEIN ENHANCER OF SEVENLESS 2B SRC-LIKE-ADAPTER 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;growth factor receptor binding#GO:0070851 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cell communication#GO:0007154 protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;COP9 signalosome#GO:0008180;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000047795.1|UniProtKB=A0A5F8GHU1 A0A5F8GHU1 PDLIM3 PTHR24214:SF7 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 3 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;heart development#GO:0007507;multicellular organismal process#GO:0032501;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular component organization#GO:0016043;circulatory system development#GO:0072359;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856 intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;I band#GO:0031674;cytoskeleton#GO:0005856;stress fiber#GO:0001725;adherens junction#GO:0005912;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;sarcomere#GO:0030017;cell junction#GO:0030054;actomyosin#GO:0042641;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;cell-cell junction#GO:0005911;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000008458.3|UniProtKB=F7GEX4 F7GEX4 YBEY PTHR46986:SF1 ENDORIBONUCLEASE YBEY, CHLOROPLASTIC ENDORIBONUCLEASE YBEY ISOFORM 1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000021170.4|UniProtKB=F6YMX9 F6YMX9 ANLN PTHR21538:SF27 ANILLIN/RHOTEKIN RTKN ANILLIN cellular component organization#GO:0016043;cell cycle#GO:0007049;cell division#GO:0051301;cell cycle process#GO:0022402;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;mitotic cell cycle#GO:0000278;actomyosin structure organization#GO:0031032;cytokinesis#GO:0000910;cortical cytoskeleton organization#GO:0030865;cytokinetic process#GO:0032506;actin filament-based process#GO:0030029;septin ring organization#GO:0031106;cytoskeleton-dependent cytokinesis#GO:0061640;cortical actin cytoskeleton organization#GO:0030866;actomyosin contractile ring assembly#GO:0000915;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;septin cytoskeleton organization#GO:0032185;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047 intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;membraneless organelle#GO:0043228;actomyosin contractile ring#GO:0005826;contractile ring#GO:0070938;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;cell periphery#GO:0071944 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000000344.4|UniProtKB=F6RUY6 F6RUY6 TNNI3K PTHR24133:SF61 ANKYRIN DOMAIN-CONTAINING ANKYRIN REPEAT DOMAIN 44 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000046193.1|UniProtKB=A0A5F8GFD2 A0A5F8GFD2 GABRB3 PTHR18945:SF571 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3 ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic anion channel activity#GO:0005253;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;chloride channel activity#GO:0005254;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836 monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;synaptic signaling#GO:0099536;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234 cell junction#GO:0030054;postsynaptic membrane#GO:0045211;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;synapse#GO:0045202;GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000011481.3|UniProtKB=F6VJF2 F6VJF2 MXD1 PTHR11969:SF18 MAX DIMERIZATION, MAD MAX DIMERIZATION PROTEIN 1 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000028395.2|UniProtKB=K7E3B3 K7E3B3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024568.3|UniProtKB=F7BTR1 F7BTR1 ZNF213 PTHR23226:SF258 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 213 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000027876.2|UniProtKB=K7E4R5 K7E4R5 PTHR12427:SF1 ATP SYNTHASE E CHAIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT E, MITOCHONDRIAL proton channel activity#GO:0015252;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324 nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate biosynthetic process#GO:0046390;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;proton motive force-driven ATP synthesis#GO:0015986;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142 respiratory chain complex#GO:0098803;membrane#GO:0016020;cytoplasm#GO:0005737;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;transporter complex#GO:1990351;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495 ATP synthase#PC00002;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000023938.1|UniProtKB=F7F885 F7F885 KCNJ2 PTHR11767:SF43 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 2 passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000005185.3|UniProtKB=F7DNF3 F7DNF3 HAUS4 PTHR16219:SF3 AUGMIN SUBUNIT 4 FAMILY MEMBER HAUS AUGMIN-LIKE COMPLEX SUBUNIT 4 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;HAUS complex#GO:0070652 MONDO|Ensembl=ENSMODG00000021408.4|UniProtKB=F7CBY6 F7CBY6 CDH19 PTHR24027:SF323 CADHERIN-23 CADHERIN-19 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell junction organization#GO:0034330;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cell migration#GO:0016477;cellular component assembly#GO:0022607;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840 membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;anchoring junction#GO:0070161 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000007151.4|UniProtKB=F7E870 F7E870 XRRA1 PTHR22710:SF2 X-RAY RADIATION RESISTANCE ASSOCIATED PROTEIN 1 XRRA1 X-RAY RADIATION RESISTANCE-ASSOCIATED PROTEIN 1 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000006849.3|UniProtKB=F6PFS5 F6PFS5 PTHR14014:SF0 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 1 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 1 sexual reproduction#GO:0019953;telomere tethering at nuclear periphery#GO:0034398;meiosis I cell cycle process#GO:0061982;organelle localization#GO:0051640;nuclear division#GO:0000280;localization#GO:0051179;organelle fission#GO:0048285;cell cycle process#GO:0022402;cell cycle#GO:0007049;telomere localization#GO:0034397;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;reproductive process#GO:0022414;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;meiotic nuclear division#GO:0140013;cellular process#GO:0009987;organelle organization#GO:0006996;chromosome localization#GO:0050000;homologous chromosome pairing at meiosis#GO:0007129 MONDO|Ensembl=ENSMODG00000007343.3|UniProtKB=A0A5F8HIA5 A0A5F8HIA5 RAD54B PTHR45629:SF16 SNF2/RAD54 FAMILY MEMBER DNA REPAIR AND RECOMBINATION PROTEIN RAD54B DNA translocase activity#GO:0015616;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097 response to stimulus#GO:0050896;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;reproductive process#GO:0022414;homologous recombination#GO:0035825;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;organelle fission#GO:0048285;sexual reproduction#GO:0019953;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;nucleobase-containing compound metabolic process#GO:0006139;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA repair#GO:0006281 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 damaged DNA-binding protein#PC00086 MONDO|Ensembl=ENSMODG00000039693.1|UniProtKB=A0A5F8G781 A0A5F8G781 KREMEN2 PTHR24269:SF15 KREMEN PROTEIN KREMEN PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Kremen#P01463 MONDO|Ensembl=ENSMODG00000023149.3|UniProtKB=F7GJH4 F7GJH4 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017686.4|UniProtKB=F7G5P5 F7G5P5 TRIM69 PTHR24103:SF286 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM69 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000004091.4|UniProtKB=A0A5F8GRS1 A0A5F8GRS1 RACK1 PTHR19868:SF0 RECEPTOR FOR ACTIVATED PROTEIN KINASE C RACK1 SMALL RIBOSOMAL SUBUNIT PROTEIN RACK1 kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;ribonucleoprotein complex binding#GO:0043021;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022 cellular component organization or biogenesis#GO:0071840;translational elongation#GO:0006414;metabolic process#GO:0008152;gene expression#GO:0010467;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;negative regulation of translation#GO:0017148;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;rescue of stalled cytosolic ribosome#GO:0072344;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;translation#GO:0006412;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of protein metabolic process#GO:0051248;primary metabolic process#GO:0044238 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000019659.4|UniProtKB=F6UA13 F6UA13 SGTB PTHR45831:SF1 LD24721P SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN BETA cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000018906.4|UniProtKB=F7C7F6 F7C7F6 TDRKH PTHR22948:SF18 TUDOR DOMAIN CONTAINING PROTEIN TUDOR AND KH DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014258.3|UniProtKB=F6XJI0 F6XJI0 BRIP1 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;response to stimulus#GO:0050896;DNA recombination#GO:0006310;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;nucleotide-excision repair#GO:0006289;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reproductive process#GO:0022414;homologous recombination#GO:0035825;DNA damage response#GO:0006974;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009;DNA helicase#PC00011 MONDO|Ensembl=ENSMODG00000007517.2|UniProtKB=A0A5F8G972 A0A5F8G972 FBXO34 PTHR16271:SF11 F-BOX ONLY PROTEIN 34/46 FAMILY MEMBER F-BOX ONLY PROTEIN 34 MONDO|Ensembl=ENSMODG00000001396.4|UniProtKB=F7F5K7 F7F5K7 TMEM196 PTHR28681:SF1 TRANSMEMBRANE PROTEIN 196 TRANSMEMBRANE PROTEIN 196 MONDO|Ensembl=ENSMODG00000004106.4|UniProtKB=A0A5F8GF67 A0A5F8GF67 LOC100018393 PTHR11662:SF459 SOLUTE CARRIER FAMILY 17 SIALIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000038872.1|UniProtKB=A0A5F8HAA7 A0A5F8HAA7 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000029571.2|UniProtKB=K7E0M1 K7E0M1 LOC103102801 PTHR12062:SF11 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE-LIKE PROTEIN MGAT4E acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238 transferase#PC00220 MONDO|Ensembl=ENSMODG00000018019.3|UniProtKB=F7AJX5 F7AJX5 BEND3 PTHR28665:SF1 BEN DOMAIN-CONTAINING PROTEIN 3 BEN DOMAIN-CONTAINING PROTEIN 3 nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;rDNA binding#GO:0000182;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677 negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;nucleus organization#GO:0006997;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;nucleolus organization#GO:0007000;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000004047.4|UniProtKB=F7C3X8 F7C3X8 STAM2 PTHR45929:SF1 JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE SIGNAL TRANSDUCING ADAPTER MOLECULE 2 intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;biological regulation#GO:0065007;protein localization to vacuole#GO:0072665;protein metabolic process#GO:0019538;localization#GO:0051179;cell communication#GO:0007154;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;endosomal transport#GO:0016197;cellular process#GO:0009987;signal transduction#GO:0007165;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular localization#GO:0051641;protein transport#GO:0015031;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of protein localization to vacuole#GO:0072666;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;signaling#GO:0023052 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000011555.4|UniProtKB=F7E8B4 F7E8B4 CDV3 PTHR16284:SF13 PROTEIN CDV3 HOMOLOG PROTEIN CDV3 HOMOLOG cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000037909.1|UniProtKB=A0A5F8HK77 A0A5F8HK77 LOC100013657 PTHR13943:SF31 HRAS-LIKE SUPPRESSOR - RELATED RETINOIC ACID RECEPTOR RESPONDER 3-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;A2-type glycerophospholipase activity#GO:0004623;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;acyltransferase activity#GO:0016746;lipase activity#GO:0016298 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000019977.3|UniProtKB=F6S8J8 F6S8J8 PTHR48002:SF5 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023997.2|UniProtKB=F7AS18 F7AS18 LOC100017954 PTHR26450:SF160 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR OLFR553 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020197.3|UniProtKB=F7G844 F7G844 LOC100027995 PTHR48002:SF68 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D10 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013299.4|UniProtKB=F7BYF9 F7BYF9 NEUROD6 PTHR19290:SF9 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;neuron development#GO:0048666;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000015078.4|UniProtKB=F7F3V5 F7F3V5 GMPPA PTHR22572:SF104 SUGAR-1-PHOSPHATE GUANYL TRANSFERASE MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE REGULATORY SUBUNIT ALPHA transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220 Mannose metabolism#P02752>Mannose 1-P guanylyl transferase#P03018 MONDO|Ensembl=ENSMODG00000020965.4|UniProtKB=F6SNE0 F6SNE0 DSCAM PTHR10075:SF51 BASIGIN RELATED CELL ADHESION MOLECULE DSCAM regulation of anatomical structure size#GO:0090066;positive regulation of cell differentiation#GO:0045597;positive regulation of cell growth#GO:0030307;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of response to external stimulus#GO:0032103;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of axonogenesis#GO:0050770;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;regulation of response to external stimulus#GO:0032101;regulation of cell growth#GO:0001558;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;positive regulation of growth#GO:0045927;positive regulation of cellular component organization#GO:0051130;regulation of cell size#GO:0008361;regulation of biological quality#GO:0065008;positive regulation of axonogenesis#GO:0050772;cellular component organization#GO:0016043;regulation of chemotaxis#GO:0050920;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;central nervous system development#GO:0007417;regulation of cell projection organization#GO:0031344;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of locomotion#GO:0040017;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;positive regulation of cell projection organization#GO:0031346;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;positive regulation of chemotaxis#GO:0050921;system development#GO:0048731;regulation of neurogenesis#GO:0050767;regulation of growth#GO:0040008;regulation of cellular process#GO:0050794;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793 cell body#GO:0044297;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000012763.4|UniProtKB=A0A5F8H5S3 A0A5F8H5S3 DNM1L PTHR11566:SF39 DYNAMIN DYNAMIN-1-LIKE PROTEIN microtubule binding#GO:0008017;GTPase activity#GO:0003924;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111 mitochondrial fission#GO:0000266;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;organelle organization#GO:0006996;cellular component organization#GO:0016043;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;mitochondrion localization#GO:0051646;organelle localization#GO:0051640;peroxisome organization#GO:0007031 intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000007573.5|UniProtKB=A0A5F8G7I0 A0A5F8G7I0 RUSC2 PTHR15591:SF14 RUN AND SH3 DOMAIN CONTAINING AP-4 COMPLEX ACCESSORY SUBUNIT RUSC2 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 MONDO|Ensembl=ENSMODG00000041518.1|UniProtKB=A0A5F8GI65 A0A5F8GI65 PTRH1 PTHR17224:SF1 PEPTIDYL-TRNA HYDROLASE PEPTIDYL-TRNA HYDROLASE hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 hydrolase#PC00121;esterase#PC00097 MONDO|Ensembl=ENSMODG00000029195.2|UniProtKB=K7E0Z8 K7E0Z8 PTHR11947:SF14 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 1, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of biosynthetic process#GO:0009889;regulation of lipid metabolic process#GO:0019216;regulation of carbohydrate metabolic process#GO:0006109;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000023663.3|UniProtKB=F6WUS7 F6WUS7 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005956.3|UniProtKB=F6WFB0 F6WFB0 PYCR2 PTHR11645:SF0 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;proteinogenic amino acid biosynthetic process#GO:0170038 reductase#PC00198;metabolite interconversion enzyme#PC00262 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 MONDO|Ensembl=ENSMODG00000016611.3|UniProtKB=A0A5F8HCU3 A0A5F8HCU3 EDN3 PTHR13874:SF11 ENDOTHELIN ENDOTHELIN-3 hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;receptor ligand activity#GO:0048018 blood circulation#GO:0008015;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of blood pressure#GO:0008217;monoatomic ion homeostasis#GO:0050801;regulation of systemic arterial blood pressure#GO:0003073;positive regulation of biological process#GO:0048518;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;system process#GO:0003008;regulation of smooth muscle contraction#GO:0006940;cellular homeostasis#GO:0019725;regulation of system process#GO:0044057;regulation of anatomical structure size#GO:0090066;muscle contraction#GO:0006936;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;regulation of muscle system process#GO:0090257;intracellular monoatomic ion homeostasis#GO:0006873;muscle system process#GO:0003012;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of biological quality#GO:0065008;regulation of muscle contraction#GO:0006937;circulatory system process#GO:0003013;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 Endothelin signaling pathway#P00019>Big ET1-4#P00574;Endothelin signaling pathway#P00019>ET1-4#P00588 MONDO|Ensembl=ENSMODG00000017796.4|UniProtKB=F7CFJ9 F7CFJ9 GYS2 PTHR10176:SF1 GLYCOGEN SYNTHASE GLYCOGEN [STARCH] SYNTHASE, LIVER glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758 carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;glycogen metabolic process#GO:0005977;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glucan biosynthetic process#GO:0009250;polysaccharide biosynthetic process#GO:0000271;energy reserve metabolic process#GO:0006112;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;glycogen biosynthetic process#GO:0005978;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Glycogen synthase D#P00709 MONDO|Ensembl=ENSMODG00000004722.3|UniProtKB=F6Y2R1 F6Y2R1 LSM7 PTHR10553:SF44 SMALL NUCLEAR RIBONUCLEOPROTEIN U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;U6 snRNP#GO:0005688;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;U2-type prespliceosome#GO:0071004;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000005692.4|UniProtKB=F6UK25 F6UK25 DIP2C PTHR22754:SF33 DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED DISCO-INTERACTING PROTEIN 2 HOMOLOG C catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000017124.4|UniProtKB=F6U3W8 F6U3W8 DCST1 PTHR21041:SF17 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE DCST1 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 fertilization#GO:0009566;reproductive process#GO:0022414;cellular process#GO:0009987;single fertilization#GO:0007338;cell-cell recognition#GO:0009988;sexual reproduction#GO:0019953;cell recognition#GO:0008037;sperm-egg recognition#GO:0035036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000003102.3|UniProtKB=A0A5F8HI35 A0A5F8HI35 UGP2 PTHR43511:SF4 FAMILY NOT NAMED UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE MONDO|Ensembl=ENSMODG00000011220.4|UniProtKB=A0A5F8HK25 A0A5F8HK25 KIF13A PTHR24115:SF458 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF13A microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817 microtubule-based movement#GO:0007018;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000011238.4|UniProtKB=A0A5F8H470 A0A5F8H470 NMT1 PTHR11377:SF7 N-MYRISTOYL TRANSFERASE GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE 1 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;cellular process#GO:0009987;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 transferase#PC00220 MONDO|Ensembl=ENSMODG00000025396.3|UniProtKB=F7GG40 F7GG40 PTHR43963:SF4 CARBONYL REDUCTASE 1-RELATED CARBONYL REDUCTASE (NADPH) oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 reductase#PC00198;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000009344.5|UniProtKB=F7GAM9 F7GAM9 TRIM67 PTHR24099:SF21 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 67 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000019426.4|UniProtKB=F6SG82 F6SG82 FAM151B PTHR21184:SF3 MENORIN (DENDRITIC BRANCHING PROTEIN) PROTEIN FAM151B cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000019307.4|UniProtKB=F7BDU1 F7BDU1 CCDC158 PTHR47615:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 MONDO|Ensembl=ENSMODG00000018855.3|UniProtKB=F7DW04 F7DW04 MMUT PTHR48101:SF4 METHYLMALONYL-COA MUTASE, MITOCHONDRIAL-RELATED METHYLMALONYL-COA MUTASE, MITOCHONDRIAL intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;tetrapyrrole binding#GO:0046906;isomerase activity#GO:0016853;heterocyclic compound binding#GO:1901363 organophosphate catabolic process#GO:0046434;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;purine-containing compound catabolic process#GO:0072523;sulfur compound catabolic process#GO:0044273;lipid catabolic process#GO:0016042;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 mutase#PC00160;isomerase#PC00135;metabolite interconversion enzyme#PC00262 Methylmalonyl pathway#P02755>Methylmalonyl-CoA mutase#P03034;Succinate to proprionate conversion#P02777>Methylmalonyl-CoA mutase#P03161 MONDO|Ensembl=ENSMODG00000024338.1|UniProtKB=F7DG62 F7DG62 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010604.4|UniProtKB=F7G891 F7G891 PTHR26453:SF294 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011451.3|UniProtKB=F6W190 F6W190 CCR1 PTHR10489:SF711 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 1 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955 defense response#GO:0006952;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052 external side of plasma membrane#GO:0009897;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000014475.4|UniProtKB=A0A5F8HAQ2 A0A5F8HAQ2 PPP2R1B PTHR10648:SF9 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 65 KDA REGULATORY SUBUNIT A BETA ISOFORM protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cell cycle process#GO:0022402;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle assembly#GO:0070925;sister chromatid cohesion#GO:0007062;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;meiotic sister chromatid cohesion#GO:0051177;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphatase modulator#PC00184 FGF signaling pathway#P00021>PP2A#P00629 MONDO|Ensembl=ENSMODG00000006313.4|UniProtKB=F7BQY7 F7BQY7 APMAP PTHR10426:SF130 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 MONDO|Ensembl=ENSMODG00000003897.3|UniProtKB=F7D853 F7D853 KPNA2 PTHR23316:SF12 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-1 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 MONDO|Ensembl=ENSMODG00000050829.1|UniProtKB=A0A5F8GNR8 A0A5F8GNR8 LOC100027530 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000005594.3|UniProtKB=A0A5F8H3G4 A0A5F8H3G4 FPGS PTHR11136:SF5 FOLYLPOLYGLUTAMATE SYNTHASE-RELATED FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;biosynthetic process#GO:0009058;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987 mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ligase#PC00142 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate synthase#P02958;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943 MONDO|Ensembl=ENSMODG00000019302.3|UniProtKB=F6RYQ1 F6RYQ1 TRAF4 PTHR10131:SF164 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000045132.1|UniProtKB=F7C278 F7C278 LOC100616763 PTHR26453:SF26 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017939.4|UniProtKB=F7E3U0 F7E3U0 CDC40 PTHR43979:SF1 PRE-MRNA-PROCESSING FACTOR 17 PRE-MRNA-PROCESSING FACTOR 17 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000048294.1|UniProtKB=A0A5F8HFW1 A0A5F8HFW1 LOC100618066 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000040146.1|UniProtKB=A0A5F8GDG2 A0A5F8GDG2 MACROH2A2 PTHR23430:SF37 HISTONE H2A CORE HISTONE MACRO-H2A.2 structural molecule activity#GO:0005198 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase I#GO:0006356;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;protein-DNA complex#GO:0032993;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000003160.3|UniProtKB=F6WDZ6 F6WDZ6 TGM1 PTHR11590:SF49 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE K acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 skin development#GO:0043588;epithelium development#GO:0060429;cell differentiation#GO:0030154;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;animal organ development#GO:0048513;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;epidermis development#GO:0008544;keratinocyte differentiation#GO:0030216 transferase#PC00220 MONDO|Ensembl=ENSMODG00000044928.1|UniProtKB=K7E1L8 K7E1L8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000161.4|UniProtKB=A0A5F8HBI0 A0A5F8HBI0 FAM149B1 PTHR31997:SF0 AGAP003710-PA PRIMARY CILIUM ASSEMBLY PROTEIN FAM149B1 cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;organelle assembly#GO:0070925;cilium organization#GO:0044782;localization#GO:0051179;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840 MONDO|Ensembl=ENSMODG00000004387.3|UniProtKB=F6SVW4 F6SVW4 GJB1 PTHR11984:SF20 CONNEXIN GAP JUNCTION BETA-1 PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 regulation of biological process#GO:0050789;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cell communication#GO:0007154 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796 cell junction protein#PC00070;gap junction#PC00105 MONDO|Ensembl=ENSMODG00000031839.2|UniProtKB=A0A5F8GNB0 A0A5F8GNB0 PTHR24027:SF431 CADHERIN-23 CADHERIN-RELATED FAMILY MEMBER 5 ISOFORM X1 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell migration#GO:0016477;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell-cell junction assembly#GO:0007043;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell adhesion#GO:0007155 anchoring junction#GO:0070161;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 MONDO|Ensembl=ENSMODG00000036628.1|UniProtKB=A0A5F8G792 A0A5F8G792 CDC20 PTHR19918:SF3 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED CELL DIVISION CYCLE PROTEIN 20 HOMOLOG binding#GO:0005488;enzyme activator activity#GO:0008047;protein-containing complex binding#GO:0044877;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;proteasomal protein catabolic process#GO:0010498;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;protein metabolic process#GO:0019538;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;primary metabolic process#GO:0044238;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;modification-dependent protein catabolic process#GO:0019941 organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000049943.1|UniProtKB=A0A5F8HDU3 A0A5F8HDU3 monDomV1R1245 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007929.1|UniProtKB=F7GI54 F7GI54 GNG3 PTHR13809:SF11 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-3 GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;side of membrane#GO:0098552;extrinsic component of plasma membrane#GO:0019897;membrane protein complex#GO:0098796;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Enkephalin release#P05913>G-Protein (s)#P05977;Enkephalin release#P05913>G-Protein (i)#P05974;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;GABA-B receptor II signaling#P05731>Ggamma#P05754;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Dopamine receptor mediated signaling pathway#P05912>Ggamma#P05967;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448 MONDO|Ensembl=ENSMODG00000013229.4|UniProtKB=A0A5F8HJJ8 A0A5F8HJJ8 MCAM PTHR11973:SF18 CELL SURFACE GLYCOPROTEIN MUC18-RELATED CELL SURFACE GLYCOPROTEIN MUC18 multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;developmental process#GO:0032502;multicellular organismal process#GO:0032501;tube development#GO:0035295;cellular process#GO:0009987;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;anatomical structure morphogenesis#GO:0009653 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000004002.4|UniProtKB=A0A5F8H3Z3 A0A5F8H3Z3 UPB1 PTHR43674:SF17 NITRILASE C965.09-RELATED BETA-UREIDOPROPIONASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Pyrimidine Metabolism#P02771>Beta-Ureidopropionase#P03127 MONDO|Ensembl=ENSMODG00000009476.4|UniProtKB=F7FNL5 F7FNL5 SHTN1 PTHR46606:SF3 SHOOTIN-1 SHOOTIN-1 system development#GO:0048731;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;regulation of cell migration#GO:0030334;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of neuron migration#GO:2001222;positive regulation of locomotion#GO:0040017;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399 axon#GO:0030424;growth cone#GO:0030426;axonal growth cone#GO:0044295;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;cell leading edge#GO:0031252;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000006885.3|UniProtKB=F6PVR9 F6PVR9 CMTM4 PTHR22776:SF29 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 4 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response#GO:0006955;immune system process#GO:0002376 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000050376.1|UniProtKB=K7E3P4 K7E3P4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016728.4|UniProtKB=F6RVT1 F6RVT1 CCDC170 PTHR18863:SF4 TSEC-2-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 170 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000019219.3|UniProtKB=A0A5F8HGM9 A0A5F8HGM9 SDAD1 PTHR12730:SF0 HSDA/SDA1-RELATED PROTEIN SDA1 HOMOLOG ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;organelle localization#GO:0051640;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;ribosomal large subunit export from nucleus#GO:0000055;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000014851.4|UniProtKB=F7BZ16 F7BZ16 HLF PTHR11988:SF28 THYROTROPH EMBRYONIC FACTOR RELATED HEPATIC LEUKEMIA FACTOR transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic leucine zipper transcription factor#PC00056;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000029488.2|UniProtKB=K7E1F9 K7E1F9 PTHR16983:SF12 UPAR/LY6 DOMAIN-CONTAINING PROTEIN GLYCOSYLPHOSPHATIDYLINOSITOL-ANCHORED HIGH DENSITY LIPOPROTEIN-BINDING PROTEIN 1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;lipoprotein particle binding#GO:0071813;enzyme binding#GO:0019899;protein-lipid complex binding#GO:0071814 homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;lipid homeostasis#GO:0055088;triglyceride homeostasis#GO:0070328 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000023805.3|UniProtKB=F7F082 F7F082 TUBB PTHR11588:SF61 TUBULIN TUBULIN BETA CHAIN binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 tubulin#PC00228;cytoskeletal protein#PC00085 Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780 MONDO|Ensembl=ENSMODG00000008225.4|UniProtKB=F6ZYA2 F6ZYA2 PTHR13056:SF0 VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;late endosome#GO:0005770;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000040813.1|UniProtKB=A0A5F8H6Q3 A0A5F8H6Q3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000022866.2|UniProtKB=F6PHG9 F6PHG9 LPAR4 PTHR24232:SF41 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 4 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001821.4|UniProtKB=F6T5I3 F6T5I3 AHCYL1 PTHR23420:SF3 ADENOSYLHOMOCYSTEINASE S-ADENOSYLHOMOCYSTEINE HYDROLASE-LIKE PROTEIN 1 catalytic activity#GO:0003824;hydrolase activity#GO:0016787 small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000017695.3|UniProtKB=F7FV67 F7FV67 PTHR10666:SF442 UBIQUITIN UBIQUITIN B LIKE 1 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626 MONDO|Ensembl=ENSMODG00000014784.4|UniProtKB=A0A5F8GGA3 A0A5F8GGA3 NOL10 PTHR14927:SF0 NUCLEOLAR PROTEIN 10 NUCLEOLAR PROTEIN 10 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000023302.2|UniProtKB=F6VBU7 F6VBU7 PTHR22749:SF14 RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE RIBOFLAVIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 small molecule metabolic process#GO:0044281;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;flavin-containing compound metabolic process#GO:0042726;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Flavin biosynthesis#P02741>FAD synthetase#P02936;Flavin biosynthesis#P02741>Riboflavin kinase#P02934 MONDO|Ensembl=ENSMODG00000017668.4|UniProtKB=F6YJA9 F6YJA9 THEMIS PTHR15215:SF1 CABIT DOMAIN-CONTAINING PROTEIN PROTEIN THEMIS regulation of immune response#GO:0050776;immune system process#GO:0002376;cell communication#GO:0007154;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;T cell receptor signaling pathway#GO:0050852;immune response-activating signaling pathway#GO:0002757;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;antigen receptor-mediated signaling pathway#GO:0050851 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000051036.1|UniProtKB=A0A5F8H2P8 A0A5F8H2P8 LOC100023283 PTHR26451:SF52 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 12D2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000016466.4|UniProtKB=A0A5F8HHU5 A0A5F8HHU5 MMP25 PTHR10201:SF142 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-25 metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;metabolic process#GO:0008152;extracellular structure organization#GO:0043062 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130;Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141 MONDO|Ensembl=ENSMODG00000038951.1|UniProtKB=A0A5F8H0Q6 A0A5F8H0Q6 LOC100024753 PTHR26454:SF77 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040009.1|UniProtKB=F6PZ80 F6PZ80 LOC100017512 PTHR26450:SF392 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000050273.1|UniProtKB=A0A5F8GS46 A0A5F8GS46 PTHR13082:SF0 SAP18 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 Hedgehog signaling pathway#P00025>Sap18#P00697 MONDO|Ensembl=ENSMODG00000007800.3|UniProtKB=F6ZJ20 F6ZJ20 PMP22 PTHR10671:SF114 EPITHELIAL MEMBRANE PROTEIN-RELATED PERIPHERAL MYELIN PROTEIN 22 glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;myelination#GO:0042552;neurogenesis#GO:0022008;anatomical structure formation involved in morphogenesis#GO:0048646;gliogenesis#GO:0042063;cellular anatomical entity morphogenesis#GO:0032989;bleb assembly#GO:0032060;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cellular component organization#GO:0016043;peripheral nervous system development#GO:0007422;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;system development#GO:0048731;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;myelin sheath#GO:0043209 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000024741.2|UniProtKB=F6ZN53 F6ZN53 HOXD12 PTHR46440:SF1 HOMEOBOX PROTEIN HOX-D12-RELATED HOMEOBOX PROTEIN HOX-D12 binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000017598.4|UniProtKB=F7AHX7 F7AHX7 EGFL7 PTHR14949:SF21 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 EPIDERMAL GROWTH FACTOR-LIKE PROTEIN 7 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;circulatory system development#GO:0072359;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;vasculature development#GO:0001944;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;developmental process#GO:0032502;tube development#GO:0035295;multicellular organismal process#GO:0032501;vasculogenesis#GO:0001570;cellular process#GO:0009987 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000001692.4|UniProtKB=A0A5F8HC49 A0A5F8HC49 CNTN2 PTHR10075:SF55 BASIGIN RELATED CONTACTIN-2 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000050568.1|UniProtKB=A0A5F8HJY4 A0A5F8HJY4 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000040910.1|UniProtKB=A0A5F8GQG1 A0A5F8GQG1 PTHR12951:SF5 RETINAL PROTEIN 4 PROTEIN UNC-119 HOMOLOG A lipid binding#GO:0008289;binding#GO:0005488 cytoskeleton-dependent cytokinesis#GO:0061640;protein transport#GO:0015031;cilium organization#GO:0044782;cytokinesis#GO:0000910;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;regulation of receptor-mediated endocytosis#GO:0048259;negative regulation of biological process#GO:0048519;cilium assembly#GO:0060271;cellular component organization#GO:0016043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of endocytosis#GO:0030100;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;organelle assembly#GO:0070925;negative regulation of transport#GO:0051051;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic cytokinesis#GO:0000281;cell cycle#GO:0007049;negative regulation of cellular component organization#GO:0051129;cell division#GO:0051301;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;mitotic cell cycle process#GO:1903047;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of cellular process#GO:0048523;transport#GO:0006810;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;macromolecule localization#GO:0033036 membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spindle pole#GO:0000922 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000023373.1|UniProtKB=F6X2M1 F6X2M1 HDHD3 PTHR46191:SF2 FAMILY NOT NAMED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 3 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000016345.4|UniProtKB=A0A5F8HHW7 A0A5F8HHW7 RIPOR3 PTHR15829:SF15 PROTEIN KINASE PKN/PRK1, EFFECTOR RIPOR FAMILY MEMBER 3 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000000232.4|UniProtKB=A0A5F8GE11 A0A5F8GE11 SDK1 PTHR13817:SF55 TITIN PROTEIN SIDEKICK-1 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;cell adhesion#GO:0007155;cell junction organization#GO:0034330;synapse assembly#GO:0007416;cellular component organization#GO:0016043;cell junction assembly#GO:0034329 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000029389.2|UniProtKB=K7E3U3 K7E3U3 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000000907.4|UniProtKB=F7A6Q8 F7A6Q8 MPND PTHR10410:SF41 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED MPN DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;deubiquitinase activity#GO:0101005;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 translation factor#PC00223;translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000005303.3|UniProtKB=F7DMJ8 F7DMJ8 DDX28 PTHR24031:SF421 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX28-RELATED cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;ribosomal large subunit assembly#GO:0000027;mitochondrial ribosome assembly#GO:0061668;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;mitochondrial large ribosomal subunit assembly#GO:1902775;cellular component organization#GO:0016043;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000041097.1|UniProtKB=A0A5F8H719 A0A5F8H719 LOC130456997 PTHR23260:SF1 KERATIN ASSOCIATED PROTEIN 3-3-RELATED KERATIN-ASSOCIATED PROTEIN 3-3 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000011188.3|UniProtKB=F6ZAI5 F6ZAI5 PAIP2B PTHR13154:SF5 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2B translation regulator activity#GO:0045182 negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of translation#GO:0017148;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000024276.2|UniProtKB=F6Z5D3 F6Z5D3 LOC100016349 PTHR48018:SF157 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009985.3|UniProtKB=F6USW2 F6USW2 POMK PTHR22618:SF2 PROTEIN O-MANNOSE KINASE PROTEIN O-MANNOSE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000003546.2|UniProtKB=A0A5F8H0K7 A0A5F8H0K7 PTHR19861:SF0 WD40 REPEAT PROTEIN SWD2 WD REPEAT-CONTAINING PROTEIN 82 chromatin binding#GO:0003682;binding#GO:0005488 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000001474.4|UniProtKB=F7AP26 F7AP26 GOLT1A PTHR21493:SF245 CGI-141-RELATED/LIPASE CONTAINING PROTEIN VESICLE TRANSPORT PROTEIN GOT1A intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000024415.2|UniProtKB=F7GFS3 F7GFS3 PTHR11227:SF27 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 2 phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289 cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cellular component assembly#GO:0022607;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;polysaccharide catabolic process#GO:0000272;pexophagy#GO:0000425;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;intracellular protein localization#GO:0008104;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;glycogen catabolic process#GO:0005980;localization#GO:0051179;vacuole organization#GO:0007033;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238 membrane#GO:0016020;phagophore assembly site#GO:0000407;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000003890.2|UniProtKB=F7D8M7 F7D8M7 PTHR10769:SF3 40S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN ES28 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000007961.3|UniProtKB=F7E9W3 F7E9W3 RPP25L PTHR13516:SF8 RIBONUCLEASE P SUBUNIT P25 RIBONUCLEASE P PROTEIN SUBUNIT P25-LIKE PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 ribonuclease MRP complex#GO:0000172;protein-containing complex#GO:0032991;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular protein-containing complex#GO:0140535;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494 RNA metabolism protein#PC00031;endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000008053.4|UniProtKB=A0A5F8GYZ2 A0A5F8GYZ2 DNAAF4 PTHR46492:SF2 DYNEIN ASSEMBLY FACTOR 4, AXONEMAL DYNEIN AXONEMAL ASSEMBLY FACTOR 4 DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;nuclear estrogen receptor binding#GO:0030331;binding#GO:0005488;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134 regionalization#GO:0003002;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;outer dynein arm assembly#GO:0036158;establishment of localization#GO:0051234;specification of symmetry#GO:0009799;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;transport#GO:0006810;microtubule-based movement#GO:0007018;determination of left/right symmetry#GO:0007368;localization#GO:0051179;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;system development#GO:0048731;organelle assembly#GO:0070925;pattern specification process#GO:0007389;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cellular component assembly#GO:0022607;heart development#GO:0007507;cytoskeleton organization#GO:0007010;determination of bilateral symmetry#GO:0009855;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;left/right pattern formation#GO:0060972;cell projection organization#GO:0030030;circulatory system development#GO:0072359;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cilium organization#GO:0044782;animal gross anatomical part developmental process#GO:0160108;inner dynein arm assembly#GO:0036159;cilium movement#GO:0003341;microtubule-based transport#GO:0099111 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000017969.3|UniProtKB=F7BVF2 F7BVF2 C1orf94 PTHR35674:SF1 CDNA SEQUENCE CK137956 CDNA SEQUENCE CK137956 MONDO|Ensembl=ENSMODG00000021499.4|UniProtKB=F7G2R3 F7G2R3 ANKRD29 PTHR24120:SF3 GH07239P ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 29 MONDO|Ensembl=ENSMODG00000005882.3|UniProtKB=A0A5F8HBB4 A0A5F8HBB4 EPHX1 PTHR21661:SF78 EPOXIDE HYDROLASE 1-RELATED EPOXIDE HYDROLASE 1 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ether hydrolase activity#GO:0016803 icosanoid metabolic process#GO:0006690;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;arachidonate metabolic process#GO:0019369;olefinic compound metabolic process#GO:0120254;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000004935.4|UniProtKB=F7AUF1 F7AUF1 TRHR PTHR46061:SF2 THYROTROPIN-RELEASING HORMONE RECEPTOR THYROTROPIN-RELEASING HORMONE RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH Receptor#P04580 MONDO|Ensembl=ENSMODG00000006018.3|UniProtKB=F7AJP6 F7AJP6 PTHR14947:SF28 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000018231.4|UniProtKB=F6PGB7 F6PGB7 DUSP16 PTHR10159:SF343 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 16 phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000023554.2|UniProtKB=F7BQU1 F7BQU1 PTHR11387:SF12 CYTOCHROME C OXIDASE SUBUNIT 6B CYTOCHROME C OXIDASE SUBUNIT 6B2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxidase#PC00175 MONDO|Ensembl=ENSMODG00000012097.4|UniProtKB=F7G4J9 F7G4J9 PTHR10751:SF117 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 6 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 G-protein#PC00020;heterotrimeric G-protein#PC00117 MONDO|Ensembl=ENSMODG00000006538.4|UniProtKB=F7BVK7 F7BVK7 PTHR24271:SF51 KALLIKREIN-RELATED GRANZYME M serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000037545.1|UniProtKB=A0A5F8GVZ1 A0A5F8GVZ1 PTHR11639:SF158 S100 CALCIUM-BINDING PROTEIN S100_CABP-9K-TYPE CALCIUM BINDING SUBDOMAIN DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000018362.3|UniProtKB=A0A5F8GHI4 A0A5F8GHI4 CEP162 PTHR34031:SF1 CENTROSOMAL PROTEIN OF 162 KDA CENTROSOMAL PROTEIN OF 162 KDA cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;organelle lumen#GO:0043233;cytoplasmic microtubule#GO:0005881;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;nuclear lumen#GO:0031981;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081 MONDO|Ensembl=ENSMODG00000017831.4|UniProtKB=A0A5F8G7K3 A0A5F8G7K3 ZUP1 PTHR24403:SF82 ZINC FINGER PROTEIN ZINC FINGER-CONTAINING UBIQUITIN PEPTIDASE 1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006366.4|UniProtKB=F7GCV7 F7GCV7 CES4A PTHR11559:SF254 CARBOXYLESTERASE CARBOXYLESTERASE 4A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 esterase#PC00097 MONDO|Ensembl=ENSMODG00000007289.4|UniProtKB=F7FCG6 F7FCG6 XPC PTHR12135:SF3 DNA REPAIR PROTEIN XP-C / RAD4 DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;mismatch repair#GO:0006298;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;nucleotide-excision repair complex#GO:0000109 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000019174.3|UniProtKB=F7BJ58 F7BJ58 PTHR11153:SF17 SIDEROFLEXIN SIDEROFLEXIN-5 carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;citrate transmembrane transporter activity#GO:0015137 localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of localization#GO:0051234;citrate transport#GO:0015746;intracellular transport#GO:0046907;tricarboxylic acid transport#GO:0006842;mitochondrial transmembrane transport#GO:1990542;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;mitochondrial transport#GO:0006839;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000016904.4|UniProtKB=F6X182 F6X182 PTHR43028:SF2 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 GOLGI-RESIDENT ADENOSINE 3',5'-BISPHOSPHATE 3'-PHOSPHATASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788 developmental process#GO:0032502;connective tissue development#GO:0061448;cellular developmental process#GO:0048869;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;multicellular organismal process#GO:0032501;tissue development#GO:0009888;chondrocyte differentiation#GO:0002062;animal gross anatomical part developmental process#GO:0160108;cartilage development#GO:0051216;system development#GO:0048731;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;cell development#GO:0048468;cell differentiation#GO:0030154 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 phosphatase#PC00181;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000013943.4|UniProtKB=F6SBV1 F6SBV1 MYL3 PTHR23048:SF2 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 3 polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;structural molecule activity#GO:0005198;isomerase activity#GO:0016853;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000018054.4|UniProtKB=F7GEL9 F7GEL9 PLEKHG6 PTHR47671:SF1 PLECKSTRIN DOMAIN-CONTAINING FAMILY G MEMBER 6 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 6 MONDO|Ensembl=ENSMODG00000004300.4|UniProtKB=F6SX86 F6SX86 FAIM2 PTHR23291:SF18 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 2 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 response to unfolded protein#GO:0006986;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;negative regulation of signal transduction#GO:0009968;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;negative regulation of neuron apoptotic process#GO:0043524;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;negative regulation of apoptotic signaling pathway#GO:2001234;cellular response to topologically incorrect protein#GO:0035967;regulation of apoptotic signaling pathway#GO:2001233;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000005781.3|UniProtKB=F6XY07 F6XY07 ABAT PTHR43206:SF1 AMINOTRANSFERASE 4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transaminase#PC00216;transferase#PC00220 Pyrimidine Metabolism#P02771>Aminotransferase#P03129;Aminobutyrate degradation#P02726>4-aminobutyrate aminotransferase#P02825;Gamma-aminobutyric acid synthesis#P04384>GABA aminotransferase#P04480 MONDO|Ensembl=ENSMODG00000007718.5|UniProtKB=F6W6Z2 F6W6Z2 ZIC2 PTHR19818:SF27 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017387.4|UniProtKB=F6SL70 F6SL70 S100A13 PTHR11639:SF57 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A13 cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;signaling receptor binding#GO:0005102;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000005392.4|UniProtKB=F6SJ33 F6SJ33 SNRPB2 PTHR10501:SF61 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B'' binding#GO:0005488;nucleic acid binding#GO:0003676;snRNA binding#GO:0017069;RNA binding#GO:0003723 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;intracellular membrane-bounded organelle#GO:0043231;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 mRNA splicing#P00058>U2#P01478 MONDO|Ensembl=ENSMODG00000039383.1|UniProtKB=A0A5F8GCQ3 A0A5F8GCQ3 LSM6 PTHR11021:SF1 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM6 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397 intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;nucleolus#GO:0005730;P-body#GO:0000932;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;U6 snRNP#GO:0005688;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;U4/U6 x U5 tri-snRNP complex#GO:0046540;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000014532.3|UniProtKB=F7ER25 F7ER25 SH3BP5 PTHR19423:SF1 SH3 DOMAIN-BINDING PROTEIN 5 SH3 DOMAIN-BINDING PROTEIN 5 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;kinase inhibitor activity#GO:0019210;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017899.3|UniProtKB=F7FGG4 F7FGG4 PTHR35673:SF1 UPF0500 PROTEIN C1ORF216 UPF0500 PROTEIN C1ORF216 MONDO|Ensembl=ENSMODG00000004418.4|UniProtKB=F7FLW6 F7FLW6 WIPI1 PTHR11227:SF23 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 1 molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;protein-macromolecule adaptor activity#GO:0030674;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936 carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;polysaccharide catabolic process#GO:0000272;polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;localization#GO:0051179;vacuole organization#GO:0007033;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;glycogen catabolic process#GO:0005980;macroautophagy#GO:0016236 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;phagophore assembly site#GO:0000407 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006996.3|UniProtKB=F6XVG8 F6XVG8 CDH11 PTHR24027:SF85 CADHERIN-23 CADHERIN-11 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular component assembly#GO:0022607;cell migration#GO:0016477;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell motility#GO:0048870;cell junction organization#GO:0034330;cell morphogenesis#GO:0000902;cell adhesion#GO:0007155;anatomical structure development#GO:0048856 membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000009972.4|UniProtKB=A0A5F8H773 A0A5F8H773 ELF5 PTHR11849:SF15 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-5 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 MONDO|Ensembl=ENSMODG00000003295.4|UniProtKB=F7EG01 F7EG01 ACVR2A PTHR23255:SF64 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-2A transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;activin binding#GO:0048185;kinase activity#GO:0016301;transferase activity#GO:0016740;protein kinase activity#GO:0004672;protein-containing complex binding#GO:0044877;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488 biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;activin receptor signaling pathway#GO:0032924 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;signaling receptor complex#GO:0043235;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;Gonadotropin-releasing hormone receptor pathway#P06664>ActRII/IIB#P06780;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>ActRII#P06747 MONDO|Ensembl=ENSMODG00000009384.3|UniProtKB=F6XDD2 F6XDD2 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED MONDO|Ensembl=ENSMODG00000018437.4|UniProtKB=F6XBM9 F6XBM9 UBXN7 PTHR23322:SF6 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 7 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010460.3|UniProtKB=F7F7Q7 F7F7Q7 NEU2 PTHR10628:SF6 SIALIDASE SIALIDASE-2 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;oligosaccharide metabolic process#GO:0009311;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;ceramide metabolic process#GO:0006672;carbohydrate catabolic process#GO:0016052;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;glycolipid metabolic process#GO:0006664;oligosaccharide catabolic process#GO:0009313;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;membrane#GO:0016020 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000023077.2|UniProtKB=F7FR63 F7FR63 LOC103092294 PTHR48001:SF186 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1G1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011689.3|UniProtKB=F7GE61 F7GE61 NPM3 PTHR22747:SF13 NUCLEOPLASMIN NUCLEOPLASMIN-3 RNA binding#GO:0003723;protein binding#GO:0005515;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;histone binding#GO:0042393 chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000023651.3|UniProtKB=H9H9G1 H9H9G1 LOC103105264 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000051155.1|UniProtKB=A0A5F8HDN2 A0A5F8HDN2 LOC100028079 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000012925.3|UniProtKB=F7GC36 F7GC36 PTHR11564:SF40 SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54 SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;signal sequence receptor activity#GO:0005048;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleic acid binding#GO:0003676;binding#GO:0005488;hydrolase activity#GO:0016787;RNA binding#GO:0003723 protein targeting#GO:0006605;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;establishment of protein localization to endoplasmic reticulum#GO:0072599;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;cytosol#GO:0005829;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000010589.4|UniProtKB=F7GHR6 F7GHR6 BOP1 PTHR17605:SF0 RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN RIBOSOME BIOGENESIS PROTEIN BOP1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843 ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058 preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;90S preribosome#GO:0030686;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000016888.4|UniProtKB=F6XJ96 F6XJ96 GLMP PTHR31981:SF1 GLYCOSYLATED LYSOSOMAL MEMBRANE PROTEIN GLYCOSYLATED LYSOSOMAL MEMBRANE PROTEIN lysosome#GO:0005764;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323 MONDO|Ensembl=ENSMODG00000006705.4|UniProtKB=F7DGU8 F7DGU8 ACP5 PTHR10161:SF68 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 iron ion binding#GO:0005506;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;acid phosphatase activity#GO:0003993;catalytic activity#GO:0003824;ferrous iron binding#GO:0008198;cation binding#GO:0043169;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 homeostatic process#GO:0042592;bone remodeling#GO:0046849;tissue remodeling#GO:0048771;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;tissue homeostasis#GO:0001894;multicellular organismal-level homeostasis#GO:0048871;bone resorption#GO:0045453 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000019775.4|UniProtKB=F6W7N1 F6W7N1 MAPKAP1 PTHR13335:SF1 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 TORC2 signaling#GO:0038203;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;TOR signaling#GO:0031929;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;TOR complex#GO:0038201;membrane#GO:0016020;cell periphery#GO:0071944;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007663.4|UniProtKB=F7FZA5 F7FZA5 ALOX12B PTHR11771:SF40 LIPOXYGENASE ARACHIDONATE 12-LIPOXYGENASE, 12R-TYPE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;catalytic activity#GO:0003824 lipid biosynthetic process#GO:0008610;icosanoid metabolic process#GO:0006690;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid modification#GO:0030258;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;arachidonate metabolic process#GO:0019369;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;perinuclear region of cytoplasm#GO:0048471 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000007928.4|UniProtKB=A0A5F8H032 A0A5F8H032 PFAS PTHR10099:SF1 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 De novo purine biosynthesis#P02738>Phosphoribosylformylglycinamide synthase#P02898 MONDO|Ensembl=ENSMODG00000001151.4|UniProtKB=A0A5F8H9N5 A0A5F8H9N5 DDR2 PTHR24416:SF295 TYROSINE-PROTEIN KINASE RECEPTOR DISCOIDIN DOMAIN-CONTAINING RECEPTOR 2 signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;binding#GO:0005488;collagen binding#GO:0005518;transmembrane signaling receptor activity#GO:0004888;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014986.4|UniProtKB=F7CG56 F7CG56 FREM1 PTHR45739:SF7 MATRIX PROTEIN, PUTATIVE-RELATED FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 1 tissue homeostasis#GO:0001894;multicellular organismal-level homeostasis#GO:0048871;cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;homeostatic process#GO:0042592;epithelial structure maintenance#GO:0010669;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;cellular process#GO:0009987 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000006879.4|UniProtKB=F6PWB0 F6PWB0 PTHR14098:SF1 SH2 DOMAIN CONTAINING PROTEIN LYMPHOCYTE CYTOSOLIC PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;myeloid leukocyte activation#GO:0002274;cell surface receptor signaling pathway#GO:0007166;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;leukocyte activation#GO:0045321;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell activation#GO:0001775;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;immune system process#GO:0002376;intracellular signal transduction#GO:0035556;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 T cell activation#P00053>SLP-76#P01321 MONDO|Ensembl=ENSMODG00000019478.4|UniProtKB=F6RB64 F6RB64 CDC20B PTHR19918:SF4 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED CELL DIVISION CYCLE PROTEIN 20 HOMOLOG B enzyme activator activity#GO:0008047;binding#GO:0005488;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234 macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;positive regulation of metabolic process#GO:0009893;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;protein metabolic process#GO:0019538;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000025110.2|UniProtKB=F6RNJ3 F6RNJ3 PTHR19359:SF158 CYTOCHROME B5 CYTOCHROME B5 TYPE B tetrapyrrole binding#GO:0046906;heme binding#GO:0020037;binding#GO:0005488 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000020901.3|UniProtKB=H9H7R4 H9H7R4 LRRC59 PTHR45752:SF4 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 59 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000451.4|UniProtKB=A0A5F8G8X8 A0A5F8G8X8 THADA PTHR14387:SF7 THADA/DEATH RECEPTOR INTERACTING PROTEIN TRNA (32-2'-O)-METHYLTRANSFERASE REGULATOR THADA molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 chemical homeostasis#GO:0048878;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;intracellular calcium ion homeostasis#GO:0006874;tRNA processing#GO:0008033;tRNA methylation#GO:0030488;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;inorganic ion homeostasis#GO:0098771;RNA modification#GO:0009451;calcium ion homeostasis#GO:0055074;methylation#GO:0032259;RNA metabolic process#GO:0016070;intracellular monoatomic ion homeostasis#GO:0006873;tRNA modification#GO:0006400;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;homeostatic process#GO:0042592 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000015612.4|UniProtKB=F6Z515 F6Z515 ATIC PTHR11692:SF0 BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;IMP metabolic process#GO:0046040;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside phosphate biosynthetic process#GO:1901293 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 De novo purine biosynthesis#P02738>AICAR transformylase#P02900;De novo purine biosynthesis#P02738>IMP cyclohydrolase#P02894 MONDO|Ensembl=ENSMODG00000022925.1|UniProtKB=F7E5H4 F7E5H4 LOC100020935 PTHR26450:SF70 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR OLFR593 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008132.4|UniProtKB=A0A5F8HBQ1 A0A5F8HBQ1 WWP1 PTHR11254:SF299 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE E3 UBIQUITIN-PROTEIN LIGASE WWP1 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 MONDO|Ensembl=ENSMODG00000016772.4|UniProtKB=A0A5F8H1Y5 A0A5F8H1Y5 SH2D2A PTHR14388:SF9 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 2A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;cell activation#GO:0001775;cellular process#GO:0009987;T cell activation#GO:0042110;immune system process#GO:0002376;leukocyte activation#GO:0045321 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 VEGF signaling pathway#P00056>VRAP#P01405;Angiogenesis#P00005>VRAP#P00196 MONDO|Ensembl=ENSMODG00000019170.4|UniProtKB=A0A5F8H306 A0A5F8H306 KCNN1 PTHR10153:SF38 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 1 calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic ion-gated channel activity#GO:0022839;ligand-gated channel activity#GO:0022834;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;gated channel activity#GO:0022836;binding#GO:0005488;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;calmodulin binding#GO:0005516 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179 neuron projection#GO:0043005;cell body#GO:0044297;cell periphery#GO:0071944;membrane#GO:0016020;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 voltage-gated ion channel#PC00241;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000041572.1|UniProtKB=F6V0B7 F6V0B7 LOC100026754 PTHR48018:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011020.4|UniProtKB=A0A5F8G9B0 A0A5F8G9B0 NEURL1 PTHR12429:SF13 NEURALIZED E3 UBIQUITIN-PROTEIN LIGASE NEURL1 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of neurogenesis#GO:0050767;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cell communication#GO:0010646;positive regulation of neurogenesis#GO:0050769;modulation of chemical synaptic transmission#GO:0050804;regulation of developmental process#GO:0050793;regulation of Notch signaling pathway#GO:0008593;regulation of nervous system development#GO:0051960;localization#GO:0051179;macromolecule localization#GO:0033036;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of synaptic plasticity#GO:0048167;transport#GO:0006810;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;establishment of localization#GO:0051234;regulation of neuronal synaptic plasticity#GO:0048168;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;endocytosis#GO:0006897;positive regulation of nervous system development#GO:0051962;regulation of signaling#GO:0023051;protein transport#GO:0015031;regulation of biological quality#GO:0065008;establishment of protein localization#GO:0045184;positive regulation of biological process#GO:0048518;regulation of trans-synaptic signaling#GO:0099177;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;import into cell#GO:0098657 postsynaptic specialization#GO:0099572;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944;cell junction#GO:0030054;postsynaptic density#GO:0014069 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Notch signaling pathway#P00045>Neuralized#P01117 MONDO|Ensembl=ENSMODG00000003357.4|UniProtKB=F6SET9 F6SET9 DTX1 PTHR12622:SF7 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX1 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;animal gross anatomical part developmental process#GO:0160108;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;proteasomal protein catabolic process#GO:0010498;cell surface receptor signaling pathway#GO:0007166;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;gliogenesis#GO:0042063;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;system development#GO:0048731;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;cell communication#GO:0007154;biological regulation#GO:0065007;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;developmental process#GO:0032502;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;neurogenesis#GO:0022008;ubiquitin-dependent protein catabolic process#GO:0006511;cellular developmental process#GO:0048869;Notch signaling pathway#GO:0007219;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000029756.1|UniProtKB=K7E122 K7E122 LOC100011788 PTHR12629:SF6 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 2-RELATED hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787 metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;alcohol metabolic process#GO:0006066;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000014441.4|UniProtKB=F7AU12 F7AU12 DIXDC1 PTHR10878:SF22 SEGMENT POLARITY PROTEIN DISHEVELLED DIXIN Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell surface receptor signaling pathway#GO:0007166 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000021242.4|UniProtKB=F7ACV6 F7ACV6 PTHR23140:SF0 RNA PROCESSING PROTEIN LD23810P U2 SNRNP-ASSOCIATED SURP MOTIF-CONTAINING PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000025686.3|UniProtKB=F6U003 F6U003 CRISP2 PTHR10334:SF577 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN 3 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000014123.4|UniProtKB=A0A5F8GM05 A0A5F8GM05 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000019834.3|UniProtKB=A0A5F8G7S3 A0A5F8G7S3 COMMD9 PTHR15663:SF4 COMM DOMAIN-CONTAINING PROTEIN 9 COMM DOMAIN-CONTAINING PROTEIN 9 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000018088.4|UniProtKB=F7FT78 F7FT78 MCHR2 PTHR24230:SF7 G-PROTEIN COUPLED RECEPTOR MELANIN-CONCENTRATING HORMONE RECEPTOR 2 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000023759.4|UniProtKB=F6TDQ9 F6TDQ9 APLP1 PTHR23103:SF13 ALZHEIMER'S DISEASE BETA-AMYLOID RELATED AMYLOID BETA PRECURSOR LIKE PROTEIN 1 signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;axon development#GO:0061564;cellular process#GO:0009987;anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;central nervous system development#GO:0007417;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000000076.4|UniProtKB=F6UP04 F6UP04 PTHR24023:SF878 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXVIII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000000723.4|UniProtKB=F6W6F0 F6W6F0 OSBPL3 PTHR10972:SF15 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 3 alcohol binding#GO:0043178;lipid binding#GO:0008289;steroid binding#GO:0005496;cholesterol binding#GO:0015485;binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934 nucleus#GO:0005634;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000024109.1|UniProtKB=F6WJR7 F6WJR7 THNSL1 PTHR43515:SF1 THREONINE SYNTHASE-LIKE 1 THREONINE SYNTHASE-LIKE 1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Threonine biosynthesis#P02781>Threonine synthase#P03190 MONDO|Ensembl=ENSMODG00000043114.1|UniProtKB=A0A5F8GC29 A0A5F8GC29 LOC100618103 PTHR26452:SF204 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000002897.3|UniProtKB=F6PQC0 F6PQC0 S100P PTHR11639:SF139 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-P protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 cellular process#GO:0009987;cell migration#GO:0016477;cell motility#GO:0048870;endothelial cell migration#GO:0043542 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000004973.4|UniProtKB=F7FL04 F7FL04 GAS2L3 PTHR46756:SF7 TRANSGELIN GAS2-LIKE PROTEIN 3 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000036911.1|UniProtKB=A0A5F8GG77 A0A5F8GG77 LYPLAL1 PTHR10655:SF74 LYSOPHOSPHOLIPASE-RELATED LYSOPHOSPHOLIPASE-LIKE PROTEIN 1 catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of protein localization to membrane#GO:1905475;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;biological regulation#GO:0065007;negative regulation of protein transport#GO:0051224;negative regulation of cellular process#GO:0048523;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of transport#GO:0051049;regulation of localization#GO:0032879 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phospholipase#PC00186;lipase#PC00143 MONDO|Ensembl=ENSMODG00000001525.4|UniProtKB=F7F418 F7F418 OBI1 PTHR14609:SF1 RING FINGER PROTEIN 219 ORC UBIQUITIN LIGASE 1 catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of DNA replication#GO:0006275 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000014836.4|UniProtKB=F7CHH2 F7CHH2 PTHR11801:SF39 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 5B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;defense response#GO:0006952;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway via STAT#GO:0097696;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to stress#GO:0006950;response to hormone#GO:0009725;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to endogenous stimulus#GO:0009719;response to peptide#GO:1901652;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561;PDGF signaling pathway#P00047>STAT#P01173;JAK/STAT signaling pathway#P00038>STAT#P01027 MONDO|Ensembl=ENSMODG00000046134.1|UniProtKB=A0A5F8H4U9 A0A5F8H4U9 PTHR23243:SF3 SUPRABASAL-SPECIFIC PROTEIN SUPRABASIN SUPRABASIN MONDO|Ensembl=ENSMODG00000043143.1|UniProtKB=A0A5F8HHR2 A0A5F8HHR2 DAPK3 PTHR24342:SF18 SERINE/THREONINE-PROTEIN KINASE 17 DEATH-ASSOCIATED PROTEIN KINASE 3 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000001238.4|UniProtKB=A0A5F8GLW0 A0A5F8GLW0 PBX1 PTHR11850:SF89 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 1 sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676 neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;sensory system development#GO:0048880;nervous system development#GO:0007399;embryo development#GO:0009790;head development#GO:0060322;positive regulation of macromolecule metabolic process#GO:0010604;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;eye development#GO:0001654;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;central nervous system development#GO:0007417;developmental process#GO:0032502;sensory organ development#GO:0007423;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;embryonic organ development#GO:0048568;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;visual system development#GO:0150063;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>Pbx1#P06729 MONDO|Ensembl=ENSMODG00000020281.6|UniProtKB=A0A5F8GS52 A0A5F8GS52 ZNF131 PTHR24399:SF35 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER PROTEIN 131 sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000006563.5|UniProtKB=F7BUK9 F7BUK9 PHF23 PTHR14571:SF8 HISTONE-LYSINE N-METHYLTRANSFERASE SET-26-RELATED PHD FINGER PROTEIN 23 regulation of macroautophagy#GO:0016241;positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;negative regulation of macroautophagy#GO:0016242;regulation of protein metabolic process#GO:0051246;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;positive regulation of protein metabolic process#GO:0051247;regulation of autophagosome assembly#GO:2000785;regulation of cellular component biogenesis#GO:0044087;negative regulation of metabolic process#GO:0009892;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;regulation of protein modification process#GO:0031399;negative regulation of autophagy#GO:0010507;regulation of protein ubiquitination#GO:0031396;regulation of autophagosome maturation#GO:1901096;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000021206.4|UniProtKB=F6UH37 F6UH37 NYAP2 PTHR22633:SF1 NEURONAL TYROSINE-PHOSPHORYLATED PHOSPHOINOSITIDE-3-KINASE ADAPTER 2-RELATED NEURONAL TYROSINE-PHOSPHORYLATED PHOSPHOINOSITIDE-3-KINASE ADAPTER 2 developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;nervous system development#GO:0007399;intracellular signaling cassette#GO:0141124;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000038799.1|UniProtKB=A0A5F8GGX9 A0A5F8GGX9 PAQR4 PTHR20855:SF138 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048154.1|UniProtKB=F7B4P5 F7B4P5 LOC100022035 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010405.4|UniProtKB=F7A7B0 F7A7B0 THSD1 PTHR16311:SF3 THROMBOSPONDIN TYPE I DOMAIN-CONTAINING 1 THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 1 cell periphery#GO:0071944;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000016335.4|UniProtKB=F7FKW0 F7FKW0 PTPN1 PTHR46047:SF2 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1 protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;protein binding#GO:0005515;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of cellular response to stress#GO:0080135;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of MAPK cascade#GO:0043409;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373 intracellular organelle#GO:0043229;endosome#GO:0005768;endoplasmic reticulum#GO:0005783;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;nucleus#GO:0005634;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 Cadherin signaling pathway#P00012>Tyrosine phosphatases#P00472 MONDO|Ensembl=ENSMODG00000006932.4|UniProtKB=F6PQY3 F6PQY3 POLDIP3 PTHR19965:SF96 RNA AND EXPORT FACTOR BINDING PROTEIN POLYMERASE DELTA-INTERACTING PROTEIN 3 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;nuclear export#GO:0051168;nuclear transport#GO:0051169;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000012126.4|UniProtKB=A0A5F8GAW2 A0A5F8GAW2 ABL1 PTHR24418:SF438 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ABL1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824 signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;positive regulation of cell motility#GO:2000147;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of cell migration#GO:0030335;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of locomotion#GO:0040017;cell surface receptor signaling pathway#GO:0007166;regulation of cell migration#GO:0030334 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 Axon guidance mediated by Slit/Robo#P00008>Abl#P00347;Integrin signalling pathway#P00034>Abl#P00946 MONDO|Ensembl=ENSMODG00000003892.5|UniProtKB=F7D8K2 F7D8K2 TNIP2 PTHR31882:SF6 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER TNFAIP3-INTERACTING PROTEIN 2 immune response-activating signaling pathway#GO:0002757;response to lipopolysaccharide#GO:0032496;regulation of response to external stimulus#GO:0032101;cellular response to lipid#GO:0071396;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;cellular response to oxygen-containing compound#GO:1901701;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;immune response-regulating signaling pathway#GO:0002764;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of RNA metabolic process#GO:0051252;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;intracellular receptor signaling pathway#GO:0030522;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;innate immune response-activating signaling pathway#GO:0002758;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;positive regulation of response to external stimulus#GO:0032103;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipopolysaccharide#GO:0071222;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;regulation of response to stress#GO:0080134;positive regulation of intracellular signal transduction#GO:1902533;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;response to other organism#GO:0051707;activation of innate immune response#GO:0002218;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of innate immune response#GO:0045089;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;intracellular signal transduction#GO:0035556;response to bacterium#GO:0009617;positive regulation of cell communication#GO:0010647;response to external biotic stimulus#GO:0043207;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of response to biotic stimulus#GO:0002831 MONDO|Ensembl=ENSMODG00000023290.2|UniProtKB=A0A5F8GC05 A0A5F8GC05 STX11 PTHR19957:SF30 SYNTAXIN SYNTAXIN-11 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 vesicle organization#GO:0016050;exocytosis#GO:0006887;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;organelle organization#GO:0006996;protein transport#GO:0015031;secretion by cell#GO:0032940;secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;vesicle fusion#GO:0006906;export from cell#GO:0140352;cellular component organization#GO:0016043 membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 MONDO|Ensembl=ENSMODG00000009098.3|UniProtKB=F7FCK2 F7FCK2 PTHR42707:SF2 ACYL-COA DEHYDROGENASE ACD11 DEHYDROGENASE oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000040783.1|UniProtKB=F6QUZ8 F6QUZ8 VN2R542 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024066.2|UniProtKB=F7DM50 F7DM50 FAM237B PTHR36690:SF1 PROTEIN FAM237A PROTEIN FAM237B MONDO|Ensembl=ENSMODG00000008372.4|UniProtKB=F7CDW7 F7CDW7 CLVS1 PTHR10174:SF72 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CLAVESIN-1 phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167 cellular process#GO:0009987;lytic vacuole organization#GO:0080171;lysosome organization#GO:0007040;organelle organization#GO:0006996;cellular component organization#GO:0016043;vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840 Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000002450.4|UniProtKB=A0A5F8GH61 A0A5F8GH61 PTHR23253:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 1 RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;translation factor activity#GO:0180051 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000007939.4|UniProtKB=F7G8Z6 F7G8Z6 MMP16 PTHR10201:SF26 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-16 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 developmental process#GO:0032502;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;metabolic process#GO:0008152;external encapsulating structure organization#GO:0045229;system development#GO:0048731;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;cellular component organization#GO:0016043;multicellular organismal process#GO:0032501;catabolic process#GO:0009056 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 MONDO|Ensembl=ENSMODG00000020608.3|UniProtKB=F6ZBG1 F6ZBG1 PTHR20835:SF0 E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED E3 UBIQUITIN-PROTEIN LIGASE PPP1R11 phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase binding#GO:0019903;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000002769.3|UniProtKB=F6YGY2 F6YGY2 PTCH1 PTHR46022:SF5 PROTEIN PATCHED PROTEIN PATCHED HOMOLOG 1 G protein-coupled receptor binding#GO:0001664;transmembrane signaling receptor activity#GO:0004888;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activity#GO:0038023;protein binding#GO:0005515;molecular transducer activity#GO:0060089 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 Hedgehog signaling pathway#P00025>Patched#P00689 MONDO|Ensembl=ENSMODG00000016785.3|UniProtKB=F7G696 F7G696 CCDC78 PTHR22106:SF5 COILED-COIL DOMAIN-CONTAINING PROTEIN 78 COILED-COIL DOMAIN-CONTAINING PROTEIN 78 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000008586.4|UniProtKB=F7CCU2 F7CCU2 PARVA PTHR12114:SF6 PARVIN ALPHA-PARVIN binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;substrate adhesion-dependent cell spreading#GO:0034446;actin cytoskeleton organization#GO:0030036;cell projection organization#GO:0030030;regulation of developmental process#GO:0050793;cilium assembly#GO:0060271;cellular component organization#GO:0016043;regulation of cell shape#GO:0008360;regulation of biological process#GO:0050789;cell-substrate adhesion#GO:0031589;regulation of biological quality#GO:0065008;cilium organization#GO:0044782;organelle assembly#GO:0070925;establishment or maintenance of cell polarity#GO:0007163;actin filament-based process#GO:0030029;cell adhesion#GO:0007155 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membraneless organelle#GO:0043228;cell junction#GO:0030054;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin and actin related protein#PC00039;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Parvin#P00945 MONDO|Ensembl=ENSMODG00000019417.4|UniProtKB=F6SYJ0 F6SYJ0 OCLN PTHR23288:SF4 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL OCCLUDIN transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 transcription by RNA polymerase II#GO:0006366;cell-cell junction organization#GO:0045216;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;snRNA metabolic process#GO:0016073;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA transcription by RNA polymerase II#GO:0042795;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;gene expression#GO:0010467;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;regulation of DNA-templated transcription elongation#GO:0032784;nucleic acid biosynthetic process#GO:0141187;regulation of transcription elongation by RNA polymerase II#GO:0034243;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;snRNA transcription#GO:0009301 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;vesicle#GO:0031982;apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;cell junction#GO:0030054;tight junction#GO:0070160;apical part of cell#GO:0045177;apical junction complex#GO:0043296;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;bicellular tight junction#GO:0005923;protein-containing complex#GO:0032991;cell periphery#GO:0071944;nucleus#GO:0005634;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000025499.3|UniProtKB=F6QYE4 F6QYE4 CCL19 PTHR12015:SF80 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 19 cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;cell migration#GO:0016477;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;positive regulation of cell migration#GO:0030335;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;regulation of cell motility#GO:2000145;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;cell chemotaxis#GO:0060326;cytokine-mediated signaling pathway#GO:0019221;inflammatory response#GO:0006954;chemotaxis#GO:0006935;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;cell surface receptor signaling pathway#GO:0007166;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;taxis#GO:0042330;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;response to peptide#GO:1901652;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 MONDO|Ensembl=ENSMODG00000009187.4|UniProtKB=F6ZNL0 F6ZNL0 PGBD2 PTHR47055:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT DERIVED 2 sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 MONDO|Ensembl=ENSMODG00000050218.1|UniProtKB=A0A5F8G4X7 A0A5F8G4X7 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017262.3|UniProtKB=F6T4F5 F6T4F5 PEX3 PTHR28080:SF1 PEROXISOMAL BIOGENESIS FACTOR 3 PEROXISOMAL BIOGENESIS FACTOR 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;peroxisomal transport#GO:0043574;peroxisome organization#GO:0007031;localization within membrane#GO:0051668 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000037595.1|UniProtKB=A0A5F8GAJ0 A0A5F8GAJ0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000004939.2|UniProtKB=F7AUA9 F7AUA9 TMEM74 PTHR16125:SF3 TRANSMEMBRANE PROTEIN 74 TRANSMEMBRANE PROTEIN 74 MONDO|Ensembl=ENSMODG00000010698.4|UniProtKB=A0A5F8HFN6 A0A5F8HFN6 FBXL6 PTHR16134:SF28 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 6 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 catalytic complex#GO:1902494;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000011198.6|UniProtKB=A0A5F8GQZ6 A0A5F8GQZ6 NCOR1 PTHR13992:SF5 NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR NUCLEAR RECEPTOR COREPRESSOR 1 transcription coregulator activity#GO:0003712;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;transcription corepressor activity#GO:0003714;binding#GO:0005488;transcription regulator activity#GO:0140110;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297 regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>N-CoR#P00770 MONDO|Ensembl=ENSMODG00000024034.2|UniProtKB=A0A5F8HG17 A0A5F8HG17 PTHR41694:SF8 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 11 POL PROTEIN-LIKE RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012622.4|UniProtKB=F6S2A8 F6S2A8 VPS41 PTHR12616:SF1 VACUOLAR PROTEIN SORTING VPS41 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 cellular response to starvation#GO:0009267;metabolic process#GO:0008152;intracellular transport#GO:0046907;cellular response to nutrient levels#GO:0031669;vacuolar transport#GO:0007034;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;membrane fusion#GO:0061025;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;response to stress#GO:0006950;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;cellular process#GO:0009987;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;macroautophagy#GO:0016236;cellular response to stress#GO:0033554;localization#GO:0051179;cellular localization#GO:0051641;process utilizing autophagic mechanism#GO:0061919;response to starvation#GO:0042594;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;vesicle fusion#GO:0006906 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770;membrane#GO:0016020;vesicle tethering complex#GO:0099023;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000042896.1|UniProtKB=A0A5F8H7L6 A0A5F8H7L6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000045422.1|UniProtKB=A0A5F8G3H7 A0A5F8G3H7 PTHR12035:SF125 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 5 binding#GO:0005488;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;small molecule binding#GO:0036094;carbohydrate derivative binding#GO:0097367;ion binding#GO:0043167;organic acid binding#GO:0043177 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000018326.3|UniProtKB=F6PSV8 F6PSV8 CRACR2A PTHR47977:SF65 RAS-RELATED PROTEIN RAB EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 4B ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000018685.4|UniProtKB=F7AEE1 F7AEE1 REG4 PTHR22803:SF147 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED REGENERATING ISLET-DERIVED PROTEIN 4 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000007852.6|UniProtKB=F7ET67 F7ET67 LTBP4 PTHR24034:SF43 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 4 transforming growth factor beta binding#GO:0050431;binding#GO:0005488;protein binding#GO:0005515;growth factor binding#GO:0019838;cytokine binding#GO:0019955 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000009407.4|UniProtKB=A0A5F8GZX5 A0A5F8GZX5 TAB1 PTHR10838:SF7 SYNAPTOGYRIN SYNAPTOGYRIN-1 exocytosis#GO:0006887;secretion by cell#GO:0032940;establishment of localization#GO:0051234;secretion#GO:0046903;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;transport#GO:0006810;regulated exocytosis#GO:0045055;export from cell#GO:0140352;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;synaptic vesicle membrane organization#GO:0048499;cellular component organization#GO:0016043 cell junction#GO:0030054;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;presynapse#GO:0098793;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000037820.1|UniProtKB=A0A5F8GXT4 A0A5F8GXT4 PTHR10562:SF131 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 2-RELATED protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein sumoylation#GO:0016925;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 p53 pathway#P00059>Sumo-1 ligase#P04635 MONDO|Ensembl=ENSMODG00000024079.1|UniProtKB=F7BYE3 F7BYE3 PTHR20383:SF9 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;termination of RNA polymerase II transcription#GO:0006369;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription termination#GO:0006353;mRNA processing#GO:0006397 nucleus#GO:0005634;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000000554.4|UniProtKB=F6XLX5 F6XLX5 CYFIP1 PTHR12195:SF4 CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED CYTOPLASMIC FMR1-INTERACTING PROTEIN 1 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;plasma membrane bounded cell projection assembly#GO:0120031;post-transcriptional regulation of gene expression#GO:0010608;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;axon guidance#GO:0007411;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;regulation of protein metabolic process#GO:0051246;cell projection assembly#GO:0030031;cellular process#GO:0009987;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;lamellipodium assembly#GO:0030032;regulation of biological process#GO:0050789 cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;synapse#GO:0045202;protein-containing complex#GO:0032991;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 scaffold/adaptor protein#PC00226 Huntington disease#P00029>p53#P00797 MONDO|Ensembl=ENSMODG00000007615.4|UniProtKB=F7C5A4 F7C5A4 RPS6KB2 PTHR24351:SF171 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE BETA-2 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;TOR signaling#GO:0031929;biological regulation#GO:0065007;signaling#GO:0023052;TORC1 signaling#GO:0038202;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 protein modifying enzyme#PC00260 PI3 kinase pathway#P00048>S6K#P01194;PDGF signaling pathway#P00047>p90RSK#P01142;p53 pathway by glucose deprivation#P04397>S6K#P04636;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888 MONDO|Ensembl=ENSMODG00000018961.3|UniProtKB=F7G0E4 F7G0E4 POLH PTHR45873:SF1 DNA POLYMERASE ETA DNA POLYMERASE ETA DNA-directed DNA polymerase activity#GO:0003887;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA biosynthetic process#GO:0071897;response to radiation#GO:0009314;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translesion synthesis#GO:0019985;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA synthesis involved in DNA replication#GO:0090592 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;site of double-strand break#GO:0035861;chromosome#GO:0005694;replication fork#GO:0005657;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000015276.4|UniProtKB=F6TM00 F6TM00 GLB1L PTHR23421:SF50 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE-1-LIKE PROTEIN hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 galactosidase#PC00104;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000018428.3|UniProtKB=F6XTZ7 F6XTZ7 HMGN3 PTHR23087:SF2 NONHISTONE CHROMOSOMAL PROTEIN HMG HIGH MOBILITY GROUP NUCLEOSOME-BINDING DOMAIN-CONTAINING PROTEIN 3 chromatin binding#GO:0003682;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000000494.5|UniProtKB=F7BGW0 F7BGW0 HOXA3 PTHR45664:SF13 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-A3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 embryo development#GO:0009790;anterior/posterior pattern specification#GO:0009952;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;skeletal system development#GO:0001501;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;skeletal system morphogenesis#GO:0048705;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;pattern specification process#GO:0007389;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000004296.3|UniProtKB=F6SXW0 F6SXW0 CNPY4 PTHR15382:SF3 CTG4A-RELATED PROTEIN CANOPY HOMOLOG 4 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 MONDO|Ensembl=ENSMODG00000020852.4|UniProtKB=F6R0Q9 F6R0Q9 PPP1R37 PTHR24112:SF68 LEUCINE-RICH REPEAT, ISOFORM F-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 37 regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cell migration#GO:0016477;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970 membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000051540.1|UniProtKB=A0A5F8H9P5 A0A5F8H9P5 PTHR48002:SF21 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003987.3|UniProtKB=F7DSU7 F7DSU7 PTHR31622:SF1 TRANSMEMBRANE PROTEIN 218 TRANSMEMBRANE PROTEIN 218 MONDO|Ensembl=ENSMODG00000040964.1|UniProtKB=Q2AB92 Q2AB92 T2R27 PTHR11394:SF58 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 7 molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025781.3|UniProtKB=F7FSV0 F7FSV0 PTHR24300:SF400 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C9 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;tetrapyrrole binding#GO:0046906;binding#GO:0005488 cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;icosanoid metabolic process#GO:0006690;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000051361.1|UniProtKB=A0A5F8GCA7 A0A5F8GCA7 PTHR31671:SF0 DIABETES AND OBESITY REGULATED, ISOFORM G TUMOR PROTEIN P53-INDUCIBLE NUCLEAR PROTEIN 1 protein-membrane adaptor activity#GO:0043495;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;vacuole organization#GO:0007033;organelle assembly#GO:0070925;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of RNA metabolic process#GO:0051254;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;macroautophagy#GO:0016236;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;process utilizing autophagic mechanism#GO:0061919;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;autophagosome organization#GO:1905037;positive regulation of biological process#GO:0048518;autophagy#GO:0006914 autophagosome#GO:0005776;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000046172.1|UniProtKB=A0A5F8G8A4 A0A5F8G8A4 PTHR21683:SF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED COILED-COIL DOMAIN CONTAINING 197 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000046484.1|UniProtKB=A0A5F8H107 A0A5F8H107 FRS3 PTHR21258:SF39 DOCKING PROTEIN RELATED FIBROBLAST GROWTH FACTOR RECEPTOR SUBSTRATE 3 signaling adaptor activity#GO:0035591;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674;fibroblast growth factor receptor binding#GO:0005104;receptor tyrosine kinase binding#GO:0030971;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;growth factor receptor binding#GO:0070851 signal transduction#GO:0007165;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;fibroblast growth factor receptor signaling pathway#GO:0008543;biological regulation#GO:0065007;response to fibroblast growth factor#GO:0071774;cell surface receptor signaling pathway#GO:0007166;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>FRS-2#P00240;FGF signaling pathway#P00021>FRS2#P00635 MONDO|Ensembl=ENSMODG00000014463.4|UniProtKB=F7A5X1 F7A5X1 CXCL14 PTHR12015:SF202 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 14 antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;immune system process#GO:0002376;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419 cytokine#PC00083 MONDO|Ensembl=ENSMODG00000006070.4|UniProtKB=F7FF08 F7FF08 ARSA PTHR42693:SF11 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE A catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000029538.2|UniProtKB=K7DZG1 K7DZG1 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000007462.4|UniProtKB=F7DAW7 F7DAW7 LOC100026853 PTHR45704:SF11 RAS-LIKE FAMILY MEMBER 11 SMALL MONOMERIC GTPASE MONDO|Ensembl=ENSMODG00000011771.4|UniProtKB=F7CW09 F7CW09 ACY1 PTHR45892:SF1 AMINOACYLASE-1 AMINOACYLASE-1 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 MONDO|Ensembl=ENSMODG00000051568.1|UniProtKB=K7E2S2 K7E2S2 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000018748.4|UniProtKB=F7EF45 F7EF45 ANKRD35 PTHR24161:SF21 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 35 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000027631.2|UniProtKB=K7DYZ0 K7DYZ0 LOC100020400 PTHR42985:SF10 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324 establishment of localization#GO:0051234;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;lipid transport#GO:0006869;macromolecule localization#GO:0033036;cellular process#GO:0009987;transmembrane transport#GO:0055085;fatty acid transport#GO:0015908;monoatomic cation transport#GO:0006812;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;monoatomic ion transport#GO:0006811;lipid localization#GO:0010876;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;sodium ion transport#GO:0006814 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000039070.1|UniProtKB=A0A5F8G407 A0A5F8G407 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000051066.1|UniProtKB=A0A5F8GVQ5 A0A5F8GVQ5 LOC100616809 PTHR26453:SF0 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13D1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000047905.1|UniProtKB=A0A5F8G6H4 A0A5F8G6H4 MYL9 PTHR23049:SF81 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT POLYPEPTIDE 9 myosin binding#GO:0017022;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;cell development#GO:0048468;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cell differentiation#GO:0030154;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle cell development#GO:0055001;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;actin filament bundle#GO:0032432;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;myosin complex#GO:0016459;actomyosin#GO:0042641;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;stress fiber#GO:0001725 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000037601.1|UniProtKB=A0A5F8GEP0 A0A5F8GEP0 TIFAB PTHR31266:SF3 TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN A FAMILY MEMBER TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN B enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;peptidase activator activity#GO:0016504;peptidase regulator activity#GO:0061134 regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;regulation of innate immune response#GO:0045088;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;toll-like receptor signaling pathway#GO:0002224;immune system process#GO:0002376;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103 MONDO|Ensembl=ENSMODG00000022785.3|UniProtKB=H9H682 H9H682 PTHR12317:SF74 DIACYLGLYCEROL O-ACYLTRANSFERASE 2-ACYLGLYCEROL O-ACYLTRANSFERASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 biosynthetic process#GO:0009058;triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000047120.1|UniProtKB=A0A5F8H3V0 A0A5F8H3V0 LOC130457871 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000021043.4|UniProtKB=A0A5F8GPY7 A0A5F8GPY7 TIAM1 PTHR46001:SF1 TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR TIAM1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of developmental process#GO:0050793;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of axonogenesis#GO:0050770;regulation of cell projection organization#GO:0031344 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622 Ras Pathway#P04393>Tiam1#P04571 MONDO|Ensembl=ENSMODG00000002557.4|UniProtKB=F7GFC3 F7GFC3 CLCN2 PTHR45720:SF6 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN 2 voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;channel activity#GO:0015267;voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 transport#GO:0006810;chloride transport#GO:0006821;monoatomic anion transport#GO:0006820;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000045089.1|UniProtKB=A0A5F8G9C1 A0A5F8G9C1 PTHR45869:SF21 C-REACTIVE PROTEIN-RELATED C-REACTIVE PROTEIN low-density lipoprotein particle binding#GO:0030169;protein-lipid complex binding#GO:0071814;lipoprotein particle binding#GO:0071813;complement binding#GO:0001848;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 response to external stimulus#GO:0009605;acute inflammatory response#GO:0002526;defense response#GO:0006952;innate immune response#GO:0045087;inflammatory response#GO:0006954;immune system process#GO:0002376;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000006300.3|UniProtKB=A0A5F8GZZ8 A0A5F8GZZ8 CST7 PTHR47141:SF1 CYSTATIN-F CYSTATIN-F molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;regulation of nervous system development#GO:0051960;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;regulation of developmental process#GO:0050793;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of system process#GO:0044057;regulation of response to stimulus#GO:0048583;negative regulation of cell activation#GO:0050866;positive regulation of cellular process#GO:0048522;regulation of macrophage activation#GO:0043030;positive regulation of biological process#GO:0048518;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;negative regulation of leukocyte activation#GO:0002695;regulation of multicellular organismal process#GO:0051239;negative regulation of response to external stimulus#GO:0032102;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;extracellular region#GO:0005576;late endosome#GO:0005770;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737;lytic vacuole#GO:0000323;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000037861.1|UniProtKB=A0A5F8G9E3 A0A5F8G9E3 TMEM217B PTHR34928:SF3 TRANSMEMBRANE PROTEIN 217 TRANSMEMBRANE PROTEIN 217B MONDO|Ensembl=ENSMODG00000018836.3|UniProtKB=A0A5F8GPU9 A0A5F8GPU9 GABPB2 PTHR24193:SF86 ANKYRIN REPEAT PROTEIN GA-BINDING PROTEIN SUBUNIT BETA-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000004738.3|UniProtKB=F6Y147 F6Y147 DOK1 PTHR21258:SF46 DOCKING PROTEIN RELATED DOCKING PROTEIN 1 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dok-R#P00180 MONDO|Ensembl=ENSMODG00000012430.4|UniProtKB=F6PJZ1 F6PJZ1 PTHR26453:SF108 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016183.4|UniProtKB=F7G8L8 F7G8L8 CCDC154 PTHR35153:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 154 KINESIN-LIKE PROTEIN MONDO|Ensembl=ENSMODG00000014322.3|UniProtKB=A0A5F8H3G5 A0A5F8H3G5 IL34 PTHR28606:SF1 INTERLEUKIN-34 INTERLEUKIN-34 cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of cell population proliferation#GO:0042127;regulation of hemopoiesis#GO:1903706;regulation of myeloid cell differentiation#GO:0045637;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of developmental process#GO:0050793;positive regulation of cell population proliferation#GO:0008284;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;regulation of cell development#GO:0060284;positive regulation of myeloid cell differentiation#GO:0045639;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interleukin superfamily#PC00128 MONDO|Ensembl=ENSMODG00000016619.4|UniProtKB=F6YNC9 F6YNC9 RHBDF1 PTHR45965:SF4 INACTIVE RHOMBOID PROTEIN INACTIVE RHOMBOID PROTEIN 1 regulation of signaling#GO:0023051;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201;regulation of secretion by cell#GO:1903530;regulation of secretion#GO:0051046;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;regulation of protein secretion#GO:0050708;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of response to stimulus#GO:0048583;regulation of localization#GO:0032879;regulation of transport#GO:0051049;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000001380.4|UniProtKB=A0A5F8GCY8 A0A5F8GCY8 MYCBP2 PTHR45943:SF1 E3 UBIQUITIN-PROTEIN LIGASE MYCBP2 E3 UBIQUITIN-PROTEIN LIGASE MYCBP2 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of synapse organization#GO:0050807;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of growth#GO:0040008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell junction assembly#GO:1901888;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;axon guidance#GO:0007411;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000011935.3|UniProtKB=F7DEL5 F7DEL5 PTHR14725:SF0 RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED MONDO|Ensembl=ENSMODG00000018382.4|UniProtKB=F6QV43 F6QV43 PTHR23406:SF17 MALIC ENZYME-RELATED NADP-DEPENDENT MALIC ENZYME oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 Pyruvate metabolism#P02772>Malic enzyme#P03136 MONDO|Ensembl=ENSMODG00000049464.1|UniProtKB=A0A5F8H381 A0A5F8H381 PTCD2 PTHR14700:SF0 PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2, MITOCHONDRIAL PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2, MITOCHONDRIAL regulation of RNA metabolic process#GO:0051252;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;mitochondrion organization#GO:0007005;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000010046.4|UniProtKB=F6TTB1 F6TTB1 VSIG8 PTHR45166:SF1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 8 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 8 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000005278.4|UniProtKB=F7E6X5 F7E6X5 LRRC32 PTHR45617:SF4 LEUCINE RICH REPEAT FAMILY PROTEIN TRANSFORMING GROWTH FACTOR BETA ACTIVATOR LRRC32 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006641.5|UniProtKB=F7G4A4 F7G4A4 PRKCSH PTHR12630:SF27 N-LINKED OLIGOSACCHARIDE PROCESSING GLUCOSIDASE 2 SUBUNIT BETA system development#GO:0048731;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;liver development#GO:0001889;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;animal organ development#GO:0048513;carbohydrate derivative biosynthetic process#GO:1901137;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;developmental process#GO:0032502;metabolic process#GO:0008152;biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000014310.4|UniProtKB=F6W4C3 F6W4C3 HLA-DMB PTHR19944:SF65 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DM BETA CHAIN antigen binding#GO:0003823;peptide binding#GO:0042277;binding#GO:0005488;protein-containing complex binding#GO:0044877 immune system process#GO:0002376;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of lymphocyte activation#GO:0051249;positive regulation of leukocyte activation#GO:0002696;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of T cell activation#GO:0050863;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte activation#GO:0051251;positive regulation of cell adhesion#GO:0045785;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of cellular process#GO:0048522;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;protein-containing complex#GO:0032991;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 MONDO|Ensembl=ENSMODG00000023217.2|UniProtKB=F7BI16 F7BI16 PTHR14845:SF3 COILED-COIL DOMAIN-CONTAINING 166 COILED-COIL DOMAIN CONTAINING 121, RETROGENE 1 MONDO|Ensembl=ENSMODG00000048304.1|UniProtKB=A0A5F8GZJ9 A0A5F8GZJ9 PTHR12015:SF208 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 27 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000047511.1|UniProtKB=A0A5F8GV06 A0A5F8GV06 PTHR24377:SF710 IP01015P-RELATED ZINC FINGER PROTEIN 181-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000012347.4|UniProtKB=F7E227 F7E227 HOXB2 PTHR45664:SF7 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-B2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000011855.4|UniProtKB=F7GDE7 F7GDE7 BTBD8 PTHR22427:SF2 GH15728P BTB_POZ DOMAIN-CONTAINING PROTEIN 8 MONDO|Ensembl=ENSMODG00000007072.4|UniProtKB=F6UEV4 F6UEV4 NR0B1 PTHR24081:SF1 NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B MEMBER 1 binding#GO:0005488;transcription regulator activity#GO:0140110;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;development of primary sexual characteristics#GO:0045137;animal organ development#GO:0048513;multicellular organism development#GO:0007275;sex differentiation#GO:0007548;male gonad development#GO:0008584;negative regulation of macromolecule biosynthetic process#GO:0010558;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;reproductive structure development#GO:0048608;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;regulation of transcription by RNA polymerase II#GO:0006357;male sex differentiation#GO:0046661;developmental process#GO:0032502;spermatogenesis#GO:0007283;negative regulation of cellular process#GO:0048523;development of primary male sexual characteristics#GO:0046546;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;gonad development#GO:0008406;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;multicellular organismal process#GO:0032501;male gamete generation#GO:0048232;regulation of nucleobase-containing compound metabolic process#GO:0019219;sexual reproduction#GO:0019953;regulation of RNA metabolic process#GO:0051252;multicellular organismal reproductive process#GO:0048609;reproductive system development#GO:0061458;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000004320.3|UniProtKB=F6X6X2 F6X6X2 LOC100025505 PTHR12560:SF6 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;ceramide metabolic process#GO:0006672 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000008265.4|UniProtKB=F6Z886 F6Z886 UBR3 PTHR21497:SF39 UBIQUITIN LIGASE E3 ALPHA-RELATED E3 UBIQUITIN-PROTEIN LIGASE UBR3 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056 catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000011042.4|UniProtKB=A0A5F8G4V1 A0A5F8G4V1 DSG1 PTHR24025:SF9 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-1 metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 cadherin#PC00057 MONDO|Ensembl=ENSMODG00000000117.3|UniProtKB=F6YBY8 F6YBY8 LTK PTHR24416:SF294 TYROSINE-PROTEIN KINASE RECEPTOR LEUKOCYTE TYROSINE KINASE RECEPTOR phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of developmental process#GO:0050793;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of neuron differentiation#GO:0045664;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;regulation of cell differentiation#GO:0045595 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000046253.1|UniProtKB=A0A5F8HL45 A0A5F8HL45 SMIM1 PTHR38503:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 1 SMALL INTEGRAL MEMBRANE PROTEIN 1 cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;homeostatic process#GO:0042592;cell development#GO:0048468;cellular process#GO:0009987;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;erythrocyte differentiation#GO:0030218;multicellular organismal-level homeostasis#GO:0048871;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000001012.1|UniProtKB=F6ZFJ2 F6ZFJ2 MTNR1B PTHR24228:SF54 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR MELATONIN RECEPTOR TYPE 1B signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of hormone secretion#GO:0046883;cell communication#GO:0007154;regulation of secretion#GO:0051046;regulation of hormone levels#GO:0010817;cellular response to stimulus#GO:0051716;regulation of protein secretion#GO:0050708;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;response to stimulus#GO:0050896;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of insulin secretion#GO:0050796;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 MONDO|Ensembl=ENSMODG00000002982.4|UniProtKB=F6Q4X8 F6Q4X8 NENF PTHR10281:SF120 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED NEUDESIN molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008690.3|UniProtKB=F6PXP0 F6PXP0 GEMIN6 PTHR14710:SF2 GEM-ASSOCIATED PROTEIN 6 GEM-ASSOCIATED PROTEIN 6 protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;SMN-Sm protein complex#GO:0034719;SMN complex#GO:0032797;protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000044133.1|UniProtKB=A0A5F8GWF6 A0A5F8GWF6 PTHR23267:SF313 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 5-2 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000049859.1|UniProtKB=F6TBU0 F6TBU0 PTHR48001:SF9 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1J2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024422.3|UniProtKB=A0A5F8GKH2 A0A5F8GKH2 TRAPPC9 PTHR21512:SF5 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987 intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;TRAPPII protein complex#GO:1990071;vesicle#GO:0031982;intracellular vesicle#GO:0097708 MONDO|Ensembl=ENSMODG00000038112.1|UniProtKB=F6ZLR5 F6ZLR5 PTHR24390:SF290 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 184 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000005200.2|UniProtKB=F7A280 F7A280 PTHR11437:SF11 RIBONUCLEASE INACTIVE RIBONUCLEASE-LIKE PROTEIN 13-RELATED RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 response to external stimulus#GO:0009605;defense response#GO:0006952;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to Gram-positive bacterium#GO:0050830 RNA metabolism protein#PC00031;endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000005667.3|UniProtKB=F6V3G3 F6V3G3 ARID3A PTHR15348:SF1 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000016324.3|UniProtKB=F6Q9N8 F6Q9N8 PTHR24098:SF14 OUTER SEGMENT 5 TRIPARTITE MOTIF-CONTAINING PROTEIN 59 cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 membrane-bounded organelle#GO:0043227;intraciliary transport particle B#GO:0030992;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000021033.4|UniProtKB=F6W0J2 F6W0J2 RRP1B PTHR13026:SF2 NNP-1 PROTEIN NOVEL NUCLEAR PROTEIN 1 NOP52 RIBOSOMAL RNA PROCESSING PROTEIN 1 HOMOLOG B transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000017319.4|UniProtKB=F6WX08 F6WX08 FBXW5 PTHR20995:SF17 F-BOX/WD REPEAT-CONTAINING PROTEIN 5 F-BOX_WD REPEAT-CONTAINING PROTEIN 5 MONDO|Ensembl=ENSMODG00000019586.4|UniProtKB=F6QM58 F6QM58 NDUFAF2 PTHR32470:SF2 ADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 2 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 2 mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000007394.3|UniProtKB=F6YZV6 F6YZV6 PTHR11937:SF168 ACTIN BETA-ACTIN-LIKE PROTEIN 2 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell junction#GO:0030054;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;organelle#GO:0043226;actin cytoskeleton#GO:0015629 actin and actin related protein#PC00039 Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944;Cadherin signaling pathway#P00012>F-actin#P00470;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 MONDO|Ensembl=ENSMODG00000016054.4|UniProtKB=A0A5F8GYA2 A0A5F8GYA2 NHERF2 PTHR14191:SF4 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR NHE-RF2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-membrane adaptor activity#GO:0043495;protein binding#GO:0005515 cellular process#GO:0009987;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010192.3|UniProtKB=F6SU02 F6SU02 PTHR11711:SF147 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 5A guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 protein localization to organelle#GO:0033365;protein localization to membrane#GO:0072657;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein localization to Golgi apparatus#GO:0034067;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 Golgi apparatus subcompartment#GO:0098791;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 G-protein#PC00020 MONDO|Ensembl=ENSMODG00000043158.1|UniProtKB=A0A5F8G9D4 A0A5F8G9D4 PTHR46110:SF5 HOMEOBOX PROTEIN HMX SENSORY ORGAN HOMEOBOX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000010195.4|UniProtKB=A0A5F8GET0 A0A5F8GET0 ADCY1 PTHR45627:SF26 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 1 phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824;adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829 cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;cyclic purine nucleotide metabolic process#GO:0052652;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 adenylate cyclase#PC00043 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;CCKR signaling map#P06959>Adenylate cyclase#P07127;Gonadotropin-releasing hormone receptor pathway#P06664>AC#P06699;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760 MONDO|Ensembl=ENSMODG00000018252.5|UniProtKB=A0A5F8HKD7 A0A5F8HKD7 POLQ PTHR10133:SF64 DNA POLYMERASE I DNA POLYMERASE THETA DNA-directed DNA polymerase activity#GO:0003887;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238 DNA-directed DNA polymerase#PC00018 MONDO|Ensembl=ENSMODG00000004007.5|UniProtKB=F7D7G7 F7D7G7 MBOAT7 PTHR13906:SF16 PORCUPINE MEMBRANE-BOUND ACYLGLYCEROPHOSPHATIDYLINOSITOL O-ACYLTRANSFERASE MBOAT7 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerophospholipid biosynthetic process#GO:0046474;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;lipid modification#GO:0030258;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407 organelle membrane contact site#GO:0044232;membrane#GO:0016020;mitochondria-associated endoplasmic reticulum membrane contact site#GO:0044233;cellular anatomical structure#GO:0110165;organelle#GO:0043226 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000043146.1|UniProtKB=A0A5F8G494 A0A5F8G494 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000009703.4|UniProtKB=F6XTS2 F6XTS2 SLC6A7 PTHR11616:SF231 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT PROLINE TRANSPORTER symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075 transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;amino acid transport#GO:0006865;establishment of localization#GO:0051234;import into cell#GO:0098657;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;glycine transport#GO:0015816;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000010586.4|UniProtKB=F7GHT2 F7GHT2 MAPRE2 PTHR10623:SF7 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER MICROTUBULE-ASSOCIATED PROTEIN RP_EB FAMILY MEMBER 2 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;protein localization to cytoskeleton#GO:0044380;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;intracellular protein localization#GO:0008104;chromosome segregation#GO:0007059;cellular component assembly#GO:0022607;protein localization to microtubule cytoskeleton#GO:0072698;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular organelle#GO:0043229;microtubule#GO:0005874;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoplasmic microtubule#GO:0005881;microtubule end#GO:1990752;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000025155.2|UniProtKB=F7GHX6 F7GHX6 LOC100015201 PTHR45904:SF1 TRNA (URACIL-5-)-METHYLTRANSFERASE TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG B RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000008209.4|UniProtKB=F7AL98 F7AL98 LYVE1 PTHR10225:SF2 HYALURONAN RECEPTOR LYMPHATIC VESSEL ENDOTHELIAL HYALURONIC ACID RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transmembrane signaling receptor activity#GO:0004888;organic acid binding#GO:0043177 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019681.4|UniProtKB=H9H7E6 H9H7E6 PPP2R2D PTHR11871:SF6 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B DELTA ISOFORM protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629 MONDO|Ensembl=ENSMODG00000000124.4|UniProtKB=F6YBQ3 F6YBQ3 KLHL1 PTHR24412:SF75 KELCH PROTEIN KELCH-LIKE PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018527.4|UniProtKB=A0A5F8HE30 A0A5F8HE30 ARID2 PTHR22970:SF14 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000017683.4|UniProtKB=A0A5F8G3E3 A0A5F8G3E3 SORD PTHR43161:SF29 SORBITOL DEHYDROGENASE SORBITOL DEHYDROGENASE alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491 carbohydrate catabolic process#GO:0016052;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;hexose biosynthetic process#GO:0019319;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;alcohol metabolic process#GO:0006066;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000006817.4|UniProtKB=F6PGF6 F6PGF6 PLD5 PTHR10185:SF9 PHOSPHOLIPASE D - RELATED INACTIVE PHOSPHOLIPASE D5 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000048038.1|UniProtKB=A0A5F8G980 A0A5F8G980 LOC100617633 PTHR24390:SF290 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 184 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000007022.3|UniProtKB=A0A5F8HCZ4 A0A5F8HCZ4 GTF2I PTHR46304:SF2 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1 GENERAL TRANSCRIPTION FACTOR II-I transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000005062.5|UniProtKB=F7ASZ3 F7ASZ3 PCSK4 PTHR42884:SF16 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 4 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;peptide hormone processing#GO:0016486;protein processing#GO:0016485;protein maturation#GO:0051604;gene expression#GO:0010467;hormone metabolic process#GO:0042445;biosynthetic process#GO:0009058;biological regulation#GO:0065007;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;proteolysis#GO:0006508;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of biological quality#GO:0065008 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 serine protease#PC00203 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 MONDO|Ensembl=ENSMODG00000012268.2|UniProtKB=F6YGA2 F6YGA2 IGF2BP1 PTHR10288:SF92 KH DOMAIN CONTAINING RNA BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of RNA catabolic process#GO:1902369;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of catabolic process#GO:0009895;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA metabolic process#GO:1903311;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;nervous system development#GO:0007399;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013 cytoplasmic stress granule#GO:0010494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;nucleus#GO:0005634;cytosol#GO:0005829 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000020594.4|UniProtKB=F7A0K9 F7A0K9 COL25A1 PTHR37456:SF3 SI:CH211-266K2.1 COLLAGEN ALPHA-1(XXV) CHAIN peptide binding#GO:0042277;binding#GO:0005488 MONDO|Ensembl=ENSMODG00000003875.4|UniProtKB=F7DTD4 F7DTD4 GRTP1 PTHR22957:SF686 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN GROWTH HORMONE-REGULATED TBC PROTEIN 1 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000020501.4|UniProtKB=A0A5F8GTX5 A0A5F8GTX5 PTHR11339:SF408 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-5B structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000009010.3|UniProtKB=F7BPX3 F7BPX3 GSX1 PTHR24339:SF29 HOMEOBOX PROTEIN EMX-RELATED GS HOMEOBOX 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;head development#GO:0060322;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000048069.1|UniProtKB=A0A5F8HC54 A0A5F8HC54 PTHR11639:SF151 S100 CALCIUM-BINDING PROTEIN PROTEIN MRP-126 metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 cellular process#GO:0009987;cell motility#GO:0048870;endothelial cell migration#GO:0043542;cell migration#GO:0016477 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000008399.4|UniProtKB=F7BV18 F7BV18 NIPAL4 PTHR12570:SF7 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED MAGNESIUM TRANSPORTER NIPA4 transport#GO:0006810;magnesium ion transport#GO:0015693;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000003290.3|UniProtKB=F7EG22 F7EG22 ADRA2C PTHR24248:SF25 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-2C ADRENERGIC RECEPTOR hormone binding#GO:0042562;G protein-coupled amine receptor activity#GO:0008227;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;cation binding#GO:0043169 adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 MONDO|Ensembl=ENSMODG00000042593.1|UniProtKB=A0A5F8GMY8 A0A5F8GMY8 ORAI1 PTHR31501:SF3 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262 transport#GO:0006810;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;metal ion transport#GO:0030001 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000006935.4|UniProtKB=A0A5F8H0B6 A0A5F8H0B6 NFIC PTHR11492:SF2 NUCLEAR FACTOR I NUCLEAR FACTOR 1 C-TYPE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000043098.1|UniProtKB=A0A5F8GNV1 A0A5F8GNV1 PTHR11880:SF2 RIBOSOMAL PROTEIN S19P FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US19 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000013292.4|UniProtKB=F6ZKA2 F6ZKA2 HMBS PTHR11557:SF0 PORPHOBILINOGEN DEAMINASE PORPHOBILINOGEN DEAMINASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;porphyrin-containing compound biosynthetic process#GO:0006779;cellular process#GO:0009987;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;tetrapyrrole biosynthetic process#GO:0033014 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 deaminase#PC00088;metabolite interconversion enzyme#PC00262 Heme biosynthesis#P02746>Hydroxymethylbilane synthase#P02983 MONDO|Ensembl=ENSMODG00000046105.1|UniProtKB=A0A5F8GK21 A0A5F8GK21 PTHR19424:SF4 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR-BINDING PROTEIN 1-LIKE PROTEIN 1 cellular response to stress#GO:0033554;response to temperature stimulus#GO:0009266;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;cellular response to heat#GO:0034605;response to heat#GO:0009408;heat acclimation#GO:0010286 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000001049.4|UniProtKB=F6YRT9 F6YRT9 TRPV5 PTHR10582:SF25 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 6 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;calcium ion transport#GO:0006816;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;calcium ion import#GO:0070509;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000043033.1|UniProtKB=A0A5F8H6I0 A0A5F8H6I0 SLC31A2 PTHR12483:SF8 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS PROTEIN SLC31A2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator activity#GO:0098772;monoatomic ion transmembrane transporter activity#GO:0015075;transporter regulator activity#GO:0141108;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324 regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;regulation of monoatomic cation transmembrane transport#GO:1904062;transport#GO:0006810;establishment of localization#GO:0051234;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;copper ion transmembrane transport#GO:0035434;metal ion transport#GO:0030001;transition metal ion transport#GO:0000041;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000041050.1|UniProtKB=F6R649 F6R649 TRIT1 PTHR11088:SF89 TRNA DIMETHYLALLYLTRANSFERASE TRNA DIMETHYLALLYLTRANSFERASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000015177.2|UniProtKB=F7BWI8 F7BWI8 LSM2 PTHR13829:SF2 SNRNP CORE PROTEIN FAMILY MEMBER U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM2 RNA binding#GO:0003723;snRNA binding#GO:0017069;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U6 snRNP#GO:0005688;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000015682.3|UniProtKB=F7E1E9 F7E1E9 TBX6 PTHR11267:SF100 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX6 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cell fate specification#GO:0001708;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 MONDO|Ensembl=ENSMODG00000041471.1|UniProtKB=A0A5F8GAP7 A0A5F8GAP7 SMKR1 PTHR37932:SF1 SMALL LYSINE-RICH PROTEIN 1 SMALL LYSINE-RICH PROTEIN 1 MONDO|Ensembl=ENSMODG00000047548.1|UniProtKB=A0A5F8GBD8 A0A5F8GBD8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013689.3|UniProtKB=F6QPN6 F6QPN6 LOC103099448 PTHR11346:SF120 GALECTIN GALACTOSIDE-BINDING SOLUBLE LECTIN 13-RELATED binding#GO:0005488;carbohydrate binding#GO:0030246 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000022847.2|UniProtKB=F6PJD6 F6PJD6 PTHR19918:SF1 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED FIZZY-RELATED PROTEIN HOMOLOG enzyme activator activity#GO:0008047;binding#GO:0005488;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;protein-containing complex binding#GO:0044877 proteasomal protein catabolic process#GO:0010498;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;protein metabolic process#GO:0019538;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000013850.4|UniProtKB=A0A5F8HI51 A0A5F8HI51 JMJD4 PTHR12480:SF6 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE JMJD4 oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;sequence-specific DNA binding#GO:0043565;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;dioxygenase activity#GO:0051213;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of protein-containing complex disassembly#GO:0043244;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein metabolic process#GO:0051247;positive regulation of cellular component organization#GO:0051130;positive regulation of translation#GO:0045727;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000013468.4|UniProtKB=A0A5F8GNW3 A0A5F8GNW3 TTC21A PTHR14699:SF2 STI2 PROTEIN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 21A cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;intraciliary retrograde transport#GO:0035721;cell projection organization#GO:0030030;cell differentiation#GO:0030154;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium organization#GO:0044782;cellular localization#GO:0051641;cilium-dependent cell motility#GO:0060285;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based transport#GO:0099111;cilium movement#GO:0003341;spermatid differentiation#GO:0048515;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;male gamete generation#GO:0048232;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;transport#GO:0006810;spermatogenesis#GO:0007283;developmental process#GO:0032502;intracellular transport#GO:0046907;flagellated sperm motility#GO:0030317;reproductive process#GO:0022414;intraciliary transport#GO:0042073;protein localization to cilium#GO:0061512;cell motility#GO:0048870;microtubule-based movement#GO:0007018;protein localization to organelle#GO:0033365;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;localization#GO:0051179;spermatid development#GO:0007286;sexual reproduction#GO:0019953 intraciliary transport particle#GO:0030990;intraciliary transport particle A#GO:0030991;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000015619.4|UniProtKB=F6YFN1 F6YFN1 PIWIL1 PTHR22891:SF46 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PIWI-LIKE PROTEIN 1 catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA binding#GO:0003723;nuclease activity#GO:0004518;nucleic acid binding#GO:0003676;binding#GO:0005488 multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;piRNA processing#GO:0034587;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulatory ncRNA-mediated gene silencing#GO:0031047;spermatogenesis#GO:0007283;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;male gamete generation#GO:0048232;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558 nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;membraneless organelle#GO:0043228 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000051128.1|UniProtKB=F6PSJ4 F6PSJ4 VN2R530 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000043703.1|UniProtKB=A0A5F8G2X4 A0A5F8G2X4 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000045341.1|UniProtKB=A0A5F8H701 A0A5F8H701 INAFM2 PTHR34929:SF4 ZGC:153157 TRANSMEMBRANE PROTEIN INAFM2-RELATED MONDO|Ensembl=ENSMODG00000021497.4|UniProtKB=F7G2S1 F7G2S1 RMC1 PTHR12897:SF4 COLON CANCER-ASSOCIATED PROTEIN MIC1 REGULATOR OF MON1-CCZ1 COMPLEX structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of catabolic process#GO:0009894;regulation of autophagy#GO:0010506;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;guanyl-nucleotide exchange factor complex#GO:0032045;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;cytoplasm#GO:0005737;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535 MONDO|Ensembl=ENSMODG00000020476.4|UniProtKB=A0A5F8GNU5 A0A5F8GNU5 PTPRQ PTHR46957:SF1 CYTOKINE RECEPTOR PHOSPHATIDYLINOSITOL PHOSPHATASE PTPRQ response to mechanical stimulus#GO:0009612;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to abiotic stimulus#GO:0009628;sensory perception of sound#GO:0007605;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of mechanical stimulus#GO:0050982;response to external stimulus#GO:0009605;system process#GO:0003008 signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013126.3|UniProtKB=F7BM72 F7BM72 YIF1B PTHR14083:SF1 YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN PROTEIN YIF1B vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;COPII-coated ER to Golgi transport vesicle#GO:0030134;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000015045.4|UniProtKB=A0A5F8G3J1 A0A5F8G3J1 PTHR23288:SF6 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL OCCLUDIN transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 nucleic acid biosynthetic process#GO:0141187;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of DNA-templated transcription, elongation#GO:0032786;snRNA transcription#GO:0009301;regulation of transcription by RNA polymerase II#GO:0006357;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;snRNA metabolic process#GO:0016073;positive regulation of biosynthetic process#GO:0009891;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;transcription by RNA polymerase II#GO:0006366;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000017898.4|UniProtKB=F7FGG8 F7FGG8 MGST1 PTHR10689:SF11 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000000330.3|UniProtKB=F6VDN3 F6VDN3 IVD PTHR43884:SF47 ACYL-COA DEHYDROGENASE ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000000221.4|UniProtKB=A0A5F8HJV5 A0A5F8HJV5 ZFYVE19 PTHR46603:SF1 ABSCISSION/NOCUT CHECKPOINT REGULATOR ABSCISSION_NOCUT CHECKPOINT REGULATOR binding#GO:0005488;phospholipid binding#GO:0005543;phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981 negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896 cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;plasma membrane#GO:0005886;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;plasma membrane region#GO:0098590;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;cleavage furrow#GO:0032154;membraneless organelle#GO:0043228;midbody#GO:0030496;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000011624.4|UniProtKB=F6U175 F6U175 CIB2 PTHR45791:SF5 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 2 small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;magnesium ion binding#GO:0000287;cation binding#GO:0043169 calcium ion homeostasis#GO:0055074;monoatomic ion homeostasis#GO:0050801;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592 cell periphery#GO:0071944;neuron projection#GO:0043005;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;stereocilium#GO:0032420;membraneless organelle#GO:0043228;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862 Ras Pathway#P04393>Rac#P04559 MONDO|Ensembl=ENSMODG00000024490.2|UniProtKB=F7E3J5 F7E3J5 PTHR11437:SF24 RIBONUCLEASE RIBONUCLEASE PANCREATIC catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518 response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707 endoribonuclease#PC00094;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000003900.2|UniProtKB=F7D846 F7D846 FGF16 PTHR11486:SF27 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 16 fibroblast growth factor receptor binding#GO:0005104;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102 animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;nervous system development#GO:0007399;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;response to fibroblast growth factor#GO:0071774;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012 extracellular region#GO:0005576;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000043839.1|UniProtKB=A0A5F8GGR0 A0A5F8GGR0 LOC100013629 PTHR11426:SF265 HISTONE H3 HISTONE H3.2 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;mitotic cell cycle process#GO:1903047;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;mitotic cell cycle#GO:0000278;nuclear division#GO:0000280;organelle localization#GO:0051640;organelle assembly#GO:0070925;kinetochore assembly#GO:0051382;organelle fission#GO:0048285;kinetochore organization#GO:0051383;localization#GO:0051179 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 MONDO|Ensembl=ENSMODG00000002779.4|UniProtKB=F6YGE4 F6YGE4 ADCY10 PTHR16305:SF28 TESTICULAR SOLUBLE ADENYLYL CYCLASE GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824 homeostatic process#GO:0042592;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological quality#GO:0065008;regulation of intracellular pH#GO:0051453;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of pH#GO:0006885;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AC#P01082;Metabotropic glutamate receptor group III pathway#P00039>AC#P01043 MONDO|Ensembl=ENSMODG00000009494.2|UniProtKB=F7F9Z1 F7F9Z1 DUSP21 PTHR46495:SF1 DUAL SPECIFICITY PROTEIN PHOSPHATASE 21 DUAL SPECIFICITY PROTEIN PHOSPHATASE 18 protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000007681.4|UniProtKB=F7FN70 F7FN70 PTHR46478:SF1 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3A MONDO|Ensembl=ENSMODG00000003071.4|UniProtKB=F6PLI8 F6PLI8 SLC19A2 PTHR10686:SF19 FOLATE TRANSPORTER THIAMINE TRANSPORTER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;vitamin transport#GO:0051180;cellular process#GO:0009987;transport#GO:0006810;nitrogen compound transport#GO:0071705 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000018338.4|UniProtKB=F6PRX6 F6PRX6 HACD2 PTHR11035:SF17 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 2 catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 dehydratase#PC00091 MONDO|Ensembl=ENSMODG00000017728.3|UniProtKB=F7ELG1 F7ELG1 CLVS2 PTHR10174:SF73 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CLAVESIN-2 phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840;lysosome organization#GO:0007040;lytic vacuole organization#GO:0080171;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000024521.2|UniProtKB=F7AJY4 F7AJY4 PTHR14449:SF2 FANCONI ANEMIA GROUP F PROTEIN FANCF FANCONI ANEMIA GROUP F PROTEIN response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950 Fanconi anaemia nuclear complex#GO:0043240;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000011173.2|UniProtKB=F6ZZ92 F6ZZ92 LOC100619842 PTHR26450:SF64 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011789.4|UniProtKB=F7CC51 F7CC51 PTHR14523:SF1 UNCHARACTERIZED PROTEIN C17ORF53 HOMOLOG HOMOLOGOUS RECOMBINATION OB-FOLD PROTEIN MONDO|Ensembl=ENSMODG00000044625.1|UniProtKB=A0A5F8H3P6 A0A5F8H3P6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000018594.2|UniProtKB=F7FCS9 F7FCS9 C11orf42 PTHR36872:SF1 GENE 5901-RELATED GENE 5901-RELATED cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;9+2 motile cilium#GO:0097729 MONDO|Ensembl=ENSMODG00000020357.4|UniProtKB=F7FK96 F7FK96 NADK2 PTHR13158:SF5 FAMILY NOT NAMED NAD KINASE 2, MITOCHONDRIAL phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 nicotinamide nucleotide metabolic process#GO:0046496;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;pyridine-containing compound metabolic process#GO:0072524;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide metabolic process#GO:0009117 MONDO|Ensembl=ENSMODG00000005373.4|UniProtKB=A0A5F8H2U8 A0A5F8H2U8 HRH2 PTHR24247:SF278 5-HYDROXYTRYPTAMINE RECEPTOR HISTAMINE H2 RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536 dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Histamine H2 receptor mediated signaling pathway#P04386>H2#P04489;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 MONDO|Ensembl=ENSMODG00000013542.4|UniProtKB=F7CLT7 F7CLT7 PTHR23239:SF137 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 10 structural molecule activity#GO:0005198 morphogenesis of an epithelium#GO:0002009;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;animal organ development#GO:0048513;developmental process#GO:0032502;epidermis development#GO:0008544;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epithelium development#GO:0060429;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000021279.2|UniProtKB=F7GEB4 F7GEB4 P2RY14 PTHR24233:SF3 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 14 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000007071.3|UniProtKB=F6UEW2 F6UEW2 LOC100012424 PTHR48001:SF128 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010068.4|UniProtKB=F6XND2 F6XND2 PTHR31545:SF2 SEEDY PROTEIN A/C FAMILY MEMBER SPEEDY PROTEIN C protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;protein binding#GO:0005515 MONDO|Ensembl=ENSMODG00000047464.1|UniProtKB=F6SM87 F6SM87 LOC100027550 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023187.2|UniProtKB=A2BDH5 A2BDH5 PRND PTHR15506:SF0 DOPPEL PRION PRION-LIKE PROTEIN DOPPEL binding#GO:0005488;small molecule binding#GO:0036094;copper ion binding#GO:0005507;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 response to chemical#GO:0042221;response to stimulus#GO:0050896;reproductive process#GO:0022414;fertilization#GO:0009566;single fertilization#GO:0007338;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to chemical stimulus#GO:0070887;sexual reproduction#GO:0019953;response to metal ion#GO:0010038 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000004191.4|UniProtKB=A0A5F8GQF0 A0A5F8GQF0 ATP11A PTHR24092:SF33 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IH intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215 transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule localization#GO:0033036;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;phospholipid transport#GO:0015914;biological regulation#GO:0065007;lipid transport#GO:0006869;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748 endoplasmic reticulum#GO:0005783;recycling endosome#GO:0055037;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000050386.1|UniProtKB=A0A5F8GGV6 A0A5F8GGV6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000015217.4|UniProtKB=A0A5F8GZH8 A0A5F8GZH8 BCO1 PTHR10543:SF132 BETA-CAROTENE DIOXYGENASE BETA,BETA-CAROTENE 15,15'-DIOXYGENASE catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 primary metabolic process#GO:0044238;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;lipid catabolic process#GO:0016042;catabolic process#GO:0009056;olefinic compound metabolic process#GO:0120254;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000045358.1|UniProtKB=F6RN74 F6RN74 LOC100021395 PTHR26452:SF974 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5W2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000016147.3|UniProtKB=F7D7B7 F7D7B7 LOC100022904 PTHR26453:SF254 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2B2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008255.5|UniProtKB=F6ZX60 F6ZX60 YTHDF3 PTHR12357:SF9 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN 3 nucleic acid binding#GO:0003676;binding#GO:0005488;molecular adaptor activity#GO:0060090;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;protein-RNA adaptor activity#GO:0140517;RNA binding#GO:0003723 regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000017733.4|UniProtKB=A0A5F8GPT8 A0A5F8GPT8 FRMD5 PTHR23280:SF5 4.1 G PROTEIN FERM DOMAIN-CONTAINING PROTEIN 5 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cell adhesion#GO:0045785 anchoring junction#GO:0070161;adherens junction#GO:0005912;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell-cell junction#GO:0005911 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000002130.4|UniProtKB=F6U0B3 F6U0B3 AP4E1 PTHR22780:SF13 ADAPTIN, ALPHA/GAMMA/EPSILON AP-4 COMPLEX SUBUNIT EPSILON-1 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119;membrane#GO:0016020;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000025581.2|UniProtKB=A0A5F8GT07 A0A5F8GT07 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;immune response-regulating signaling pathway#GO:0002764 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000008313.4|UniProtKB=A0A5F8HK50 A0A5F8HK50 STARD7 PTHR19308:SF8 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN STAR-RELATED LIPID TRANSFER PROTEIN 7, MITOCHONDRIAL MONDO|Ensembl=ENSMODG00000017973.4|UniProtKB=A0A5F8G7X9 A0A5F8G7X9 PPIL6 PTHR11071:SF585 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 6-RELATED chaperone#PC00072 MONDO|Ensembl=ENSMODG00000003108.4|UniProtKB=A0A5F8HGR6 A0A5F8HGR6 FAT3 PTHR24026:SF49 FAT ATYPICAL CADHERIN-RELATED PROTOCADHERIN FAT 3 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell-cell junction#GO:0005911 cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000049903.1|UniProtKB=A0A5F8GST9 A0A5F8GST9 HS3ST2 PTHR10605:SF10 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 2 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000021165.4|UniProtKB=F6XXA9 F6XXA9 ACAA1 PTHR43853:SF8 3-KETOACYL-COA THIOLASE, PEROXISOMAL 3-KETOACYL-COA THIOLASE, PEROXISOMAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;lipid modification#GO:0030258;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000002037.3|UniProtKB=F6QW59 F6QW59 ENGASE PTHR13246:SF1 ENDO BETA N-ACETYLGLUCOSAMINIDASE CYTOSOLIC ENDO-BETA-N-ACETYLGLUCOSAMINIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 deaminase#PC00088;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000003952.3|UniProtKB=F7FZ37 F7FZ37 PTHR14817:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 15 COILED-COIL DOMAIN-CONTAINING PROTEIN 15 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813 MONDO|Ensembl=ENSMODG00000022937.2|UniProtKB=F6PZ40 F6PZ40 LOC100020450 PTHR26450:SF35 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007761.4|UniProtKB=F7BJ14 F7BJ14 CDR2 PTHR19232:SF1 CENTROCORTIN FAMILY MEMBER CEREBELLAR DEGENERATION-RELATED PROTEIN 2 MONDO|Ensembl=ENSMODG00000024170.2|UniProtKB=A0A5F8HAF0 A0A5F8HAF0 VN2R652 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000036445.1|UniProtKB=A0A5F8GIW2 A0A5F8GIW2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000018791.4|UniProtKB=F7DEW4 F7DEW4 MLIP PTHR31514:SF1 MUSCULAR LMNA-INTERACTING PROTEIN MLIP MUSCULAR LMNA-INTERACTING PROTEIN MONDO|Ensembl=ENSMODG00000012036.3|UniProtKB=F7ALP1 F7ALP1 LOC103092677 PTHR11937:SF414 ACTIN ACTIN, CYTOPLASMIC 1 binding#GO:0005488;kinase binding#GO:0019900;structural constituent of cytoskeleton#GO:0005200;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515;structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036 H4 histone acetyltransferase complex#GO:1902562;membrane#GO:0016020;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular protein-containing complex#GO:0140535;cytoskeleton#GO:0005856;transferase complex#GO:1990234;plasma membrane bounded cell projection#GO:0120025;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;axon#GO:0030424;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;neuron projection#GO:0043005;cell junction#GO:0030054;histone acetyltransferase complex#GO:0000123;actin filament#GO:0005884;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470 MONDO|Ensembl=ENSMODG00000010852.4|UniProtKB=F6YDZ6 F6YDZ6 LOC100029038 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016806.4|UniProtKB=F6S089 F6S089 LOXL2 PTHR45817:SF1 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;developmental process#GO:0032502;multicellular organismal process#GO:0032501;tube development#GO:0035295;cellular process#GO:0009987;collagen fibril organization#GO:0030199;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;extracellular matrix organization#GO:0030198;system development#GO:0048731;external encapsulating structure organization#GO:0045229;sprouting angiogenesis#GO:0002040;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;circulatory system development#GO:0072359;cellular component organization#GO:0016043;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 oxidoreductase#PC00176;oxidase#PC00175 MONDO|Ensembl=ENSMODG00000012656.4|UniProtKB=A0A5F8G6R0 A0A5F8G6R0 RALGDS PTHR23113:SF35 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 Ras Pathway#P04393>RalGDS#P04551 MONDO|Ensembl=ENSMODG00000024823.2|UniProtKB=F7AB08 F7AB08 PTHR12817:SF3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;cis-Golgi network#GO:0005801 MONDO|Ensembl=ENSMODG00000007037.1|UniProtKB=F6UFP3 F6UFP3 SMDT1 PTHR33904:SF1 ESSENTIAL MCU REGULATOR, MITOCHONDRIAL ESSENTIAL MCU REGULATOR, MITOCHONDRIAL mitochondrial calcium ion homeostasis#GO:0051560;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;calcium channel complex#GO:0034704;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;mitochondrial protein-containing complex#GO:0098798;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;transporter complex#GO:1990351;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cation channel complex#GO:0034703 MONDO|Ensembl=ENSMODG00000019689.4|UniProtKB=H9H7E7 H9H7E7 EIF6 PTHR10784:SF0 TRANSLATION INITIATION FACTOR 6 EUKARYOTIC TRANSLATION INITIATION FACTOR 6 ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ribosomal large subunit binding#GO:0043023;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;organelle assembly#GO:0070925;organelle localization#GO:0051640;nuclear transport#GO:0051169;rRNA processing#GO:0006364;nuclear export#GO:0051168;localization#GO:0051179;protein-RNA complex assembly#GO:0022618;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;rRNA metabolic process#GO:0016072;intracellular transport#GO:0046907;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;macromolecule biosynthetic process#GO:0009059;ribosomal large subunit assembly#GO:0000027;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000028358.2|UniProtKB=K7DZ38 K7DZ38 PTHR22804:SF24 AGGRECAN/VERSICAN PROTEOGLYCAN NEUROCAN CORE PROTEIN anatomical structure development#GO:0048856;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399 extracellular matrix#GO:0031012;membrane#GO:0016020;external encapsulating structure#GO:0030312;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;extracellular region#GO:0005576;cell junction#GO:0030054 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 MONDO|Ensembl=ENSMODG00000023511.3|UniProtKB=F7DEK8 F7DEK8 PTHR24376:SF38 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 544-RELATED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000020663.2|UniProtKB=A0A5F8GWI3 A0A5F8GWI3 PTHR22850:SF223 WD40 REPEAT FAMILY RB BINDING PROTEIN 4, CHROMATIN REMODELING FACTOR protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;histone deacetylase complex#GO:0000118;PcG protein complex#GO:0031519;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000020034.3|UniProtKB=A0A5F8HLT1 A0A5F8HLT1 LOC100023674 PTHR26452:SF830 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5T7 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000011290.4|UniProtKB=F6WZD9 F6WZD9 ESD PTHR10061:SF0 S-FORMYLGLUTATHIONE HYDROLASE S-FORMYLGLUTATHIONE HYDROLASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;hydrolase activity#GO:0016787 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 serine protease#PC00203;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000001884.4|UniProtKB=F6WGH7 F6WGH7 POLR3B PTHR20856:SF8 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC2 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase III#GO:0042796;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;snRNA transcription#GO:0009301;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000015817.4|UniProtKB=F7FE41 F7FE41 GAREM2 PTHR14454:SF5 GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN FAMILY MEMBER GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN 2 MONDO|Ensembl=ENSMODG00000019709.3|UniProtKB=A0A5F8GEW9 A0A5F8GEW9 MTX3 PTHR12289:SF30 METAXIN RELATED METAXIN-3 protein localization to mitochondrion#GO:0070585;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;protein insertion into mitochondrial outer membrane#GO:0045040;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;mitochondrial membrane organization#GO:0007006;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;protein-containing complex organization#GO:0043933;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594 mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial outer membrane translocase complex#GO:0005742;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 MONDO|Ensembl=ENSMODG00000017238.4|UniProtKB=F6TLF9 F6TLF9 PTHR23073:SF13 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 7 isomerase activity#GO:0016853;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;proteasome complex#GO:0000502;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000040177.1|UniProtKB=A0A5F8HHP9 A0A5F8HHP9 PTHR11783:SF212 SULFOTRANSFERASE SULT SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000013939.4|UniProtKB=F6SCL6 F6SCL6 CLIC4 PTHR43920:SF7 CHLORIDE INTRACELLULAR CHANNEL, ISOFORM A CHLORIDE INTRACELLULAR CHANNEL PROTEIN 4 passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 localization#GO:0051179;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transport#GO:0006821;monoatomic anion transport#GO:0006820;transport#GO:0006810 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000019567.4|UniProtKB=F6Z1X2 F6Z1X2 PTHR21510:SF15 AKNA DOMAIN-CONTAINING PROTEIN MICROTUBULE ORGANIZATION PROTEIN AKNA system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;cell population proliferation#GO:0008283;animal gross anatomical part developmental process#GO:0160108;regulation of cell-cell adhesion#GO:0022407;forebrain development#GO:0030900;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;central nervous system development#GO:0007417;cell division#GO:0051301;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;mesenchyme development#GO:0060485;neurogenesis#GO:0022008;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;mesenchymal cell differentiation#GO:0048762;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;nervous system development#GO:0007399;head development#GO:0060322;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;tissue development#GO:0009888;negative regulation of cell adhesion#GO:0007162;brain development#GO:0007420;negative regulation of cell-cell adhesion#GO:0022408;cellular process#GO:0009987 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000015238.5|UniProtKB=F6UK80 F6UK80 UHRF2 PTHR14140:SF3 E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED E3 UBIQUITIN-PROTEIN LIGASE UHRF2 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;post-translational protein modification#GO:0043687;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000038499.1|UniProtKB=A0A5F8GWJ3 A0A5F8GWJ3 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000036784.1|UniProtKB=A0A5F8GBU1 A0A5F8GBU1 PTHR11227:SF27 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 2 lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;protein-macromolecule adaptor activity#GO:0030674;ion binding#GO:0043167;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090 localization#GO:0051179;vacuole organization#GO:0007033;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;pexophagy#GO:0000425;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;intracellular protein localization#GO:0008104;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;glycogen catabolic process#GO:0005980;carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;polysaccharide catabolic process#GO:0000272;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;phagophore assembly site#GO:0000407 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000024072.2|UniProtKB=F6ZJ33 F6ZJ33 LOC100016646 PTHR46897:SF1 VESICLE-ASSOCIATED MEMBRANE PROTEIN 4 VESICLE-ASSOCIATED MEMBRANE PROTEIN 4 endocytic recycling#GO:0032456;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;localization#GO:0051179;cellular localization#GO:0051641;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;regulation of protein localization to membrane#GO:1905475;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;regulation of transport#GO:0051049;regulation of localization#GO:0032879;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 vesicle membrane#GO:0012506;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;presynapse#GO:0098793;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;cell junction#GO:0030054;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 MONDO|Ensembl=ENSMODG00000003299.3|UniProtKB=A0A5F8GT25 A0A5F8GT25 DBNDD1 PTHR16294:SF4 DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN DYSBINDIN DOMAIN-CONTAINING PROTEIN 1 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 MONDO|Ensembl=ENSMODG00000045284.1|UniProtKB=A0A5F8HKJ1 A0A5F8HKJ1 LOC100022852 PTHR26450:SF123 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52H1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000029100.2|UniProtKB=K7E5Z3 K7E5Z3 PTHR24377:SF980 IP01015P-RELATED ZINC FINGER PROTEIN 420 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000051421.1|UniProtKB=A0A5F8GXD5 A0A5F8GXD5 TCEANC2 PTHR11477:SF14 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A N-TERMINAL AND CENTRAL DOMAIN-CONTAINING PROTEIN 2 transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000043175.1|UniProtKB=A0A5F8GKP6 A0A5F8GKP6 PLAG1 PTHR24390:SF180 ZINC FINGER PROTEIN ZINC FINGER PROTEIN PLAG1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020443.4|UniProtKB=F7AQI1 F7AQI1 ATP8B1 PTHR24092:SF48 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IC intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled intramembrane lipid carrier activity#GO:0140326 localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;lipid transport#GO:0006869;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000003590.3|UniProtKB=F6R5S3 F6R5S3 PTHR11346:SF98 GALECTIN GALECTIN-RELATED PROTEIN carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000043692.1|UniProtKB=A0A5F8H849 A0A5F8H849 LOC100011316 PTHR26453:SF255 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000041638.1|UniProtKB=A0A5F8H217 A0A5F8H217 PTHR22588:SF5 VWFA DOMAIN-CONTAINING PROTEIN COLLAGEN ALPHA-6(VI) CHAIN cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000049408.1|UniProtKB=A0A5F8HFL1 A0A5F8HFL1 PTHR36466:SF1 BCL-2-LIKE PROTEIN 15 BCL-2-LIKE PROTEIN 15 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000017604.3|UniProtKB=A0A5F8GIR5 A0A5F8GIR5 DIPK1B PTHR21093:SF3 DIVERGENT PROTEIN KINASE DOMAIN 1C-RELATED DIVERGENT PROTEIN KINASE DOMAIN 1B MONDO|Ensembl=ENSMODG00000021035.4|UniProtKB=F6W0H8 F6W0H8 CSTB PTHR11414:SF22 CYSTATIN FAMILY MEMBER CYSTATIN-B endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000013841.4|UniProtKB=F6VXB0 F6VXB0 PTHR24250:SF30 CHYMOTRYPSIN-RELATED SERINE PROTEASE 38 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 protein modifying enzyme#PC00260;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000012835.4|UniProtKB=F7DCK4 F7DCK4 AK7 PTHR23359:SF105 NUCLEOTIDE KINASE ADENYLATE KINASE 7 phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137;nucleotide kinase#PC00172 MONDO|Ensembl=ENSMODG00000014199.4|UniProtKB=F6TR11 F6TR11 CNOT1 PTHR13162:SF8 CCR4-NOT TRANSCRIPTION COMPLEX CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1 regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;CCR4-NOT complex#GO:0030014;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000009383.4|UniProtKB=F7CPS4 F7CPS4 PTHR24300:SF364 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;tetrapyrrole binding#GO:0046906;binding#GO:0005488;steroid hydroxylase activity#GO:0008395 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to chemical#GO:0042221;steroid metabolic process#GO:0008202;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000017068.4|UniProtKB=F6XHC9 F6XHC9 OPRL1 PTHR24229:SF11 NEUROPEPTIDES RECEPTOR NOCICEPTIN RECEPTOR G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;peptide binding#GO:0042277;neuropeptide binding#GO:0042923 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;sensory perception of pain#GO:0019233;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 MONDO|Ensembl=ENSMODG00000015687.3|UniProtKB=F7E0W7 F7E0W7 PTHR44027:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5G chaperone#PC00072 MONDO|Ensembl=ENSMODG00000006282.3|UniProtKB=A0A5F8HBK8 A0A5F8HBK8 FGF14 PTHR11486:SF18 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 14 ion channel regulator activity#GO:0099106;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;fibroblast growth factor receptor binding#GO:0005104;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;transporter regulator activity#GO:0141108;protein binding#GO:0005515;channel regulator activity#GO:0016247;molecular function activator activity#GO:0140677 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of cell migration#GO:0030334;response to fibroblast growth factor#GO:0071774;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000003514.4|UniProtKB=F7C801 F7C801 PTHR11675:SF129 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE-LIKE 6 glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000029415.2|UniProtKB=K7E641 K7E641 LOC103094747 PTHR11430:SF142 LIPOCALIN LIPOCALIN_CYTOSOLIC FATTY-ACID BINDING DOMAIN-CONTAINING PROTEIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000027811.2|UniProtKB=K7E066 K7E066 PTHR46289:SF23 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE MONDO|Ensembl=ENSMODG00000012572.3|UniProtKB=F6PKW2 F6PKW2 PTHR12247:SF79 POLYCOMB GROUP PROTEIN MBT DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000003094.3|UniProtKB=F6Z1B7 F6Z1B7 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000041567.1|UniProtKB=K7E2M1 K7E2M1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000042234.1|UniProtKB=A0A5F8G707 A0A5F8G707 DUSP29 PTHR45682:SF6 AGAP008228-PA DUAL SPECIFICITY PHOSPHATASE 29 catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000023797.1|UniProtKB=F6SCZ5 F6SCZ5 LOC100019625 PTHR31022:SF4 CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 regulation of mitotic spindle assembly#GO:1901673;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of organelle assembly#GO:1902115;regulation of mitotic spindle organization#GO:0060236;regulation of spindle assembly#GO:0090169;regulation of microtubule-based process#GO:0032886;regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of spindle organization#GO:0090224;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;axon#GO:0030424;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cytoplasm#GO:0005737;ciliary plasm#GO:0097014;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000023076.2|UniProtKB=F6UX75 F6UX75 PTHR12186:SF3 SIKE FAMILY MEMBER FGFR1 ONCOGENE PARTNER 2 response to stress#GO:0006950;response to wounding#GO:0009611;response to stimulus#GO:0050896 MONDO|Ensembl=ENSMODG00000005960.4|UniProtKB=F6SAK9 F6SAK9 BIVM PTHR16171:SF13 DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED BASIC IMMUNOGLOBULIN-LIKE VARIABLE MOTIF-CONTAINING PROTEIN nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097 macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleotide-excision repair complex#GO:0000109;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000025666.3|UniProtKB=F6XDE0 F6XDE0 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED MONDO|Ensembl=ENSMODG00000006320.3|UniProtKB=F7B3Q9 F7B3Q9 FBXO43 PTHR15493:SF1 F-BOX ONLY PROTEIN 5 AND 43 F-BOX ONLY PROTEIN 43 enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 mitotic cell cycle phase transition#GO:0044772;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;regulation of cellular component organization#GO:0051128;mitotic cell cycle#GO:0000278;regulation of cell cycle#GO:0051726;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;cell cycle#GO:0007049;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;negative regulation of cell cycle#GO:0045786;mitotic cell cycle process#GO:1903047;regulation of mitotic nuclear division#GO:0007088;G1/S transition of mitotic cell cycle#GO:0000082;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;regulation of reproductive process#GO:2000241;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000008487.4|UniProtKB=F7G454 F7G454 MTRF1L PTHR43804:SF3 LD18447P PEPTIDE CHAIN RELEASE FACTOR 1-LIKE, MITOCHONDRIAL gene expression#GO:0010467;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;protein-containing complex disassembly#GO:0032984;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;translational termination#GO:0006415;translation#GO:0006412 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 translation release factor#PC00225;translational protein#PC00263;translation factor#PC00223 MONDO|Ensembl=ENSMODG00000025419.2|UniProtKB=F6VVI4 F6VVI4 PTHR12297:SF5 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1A, MITOCHONDRIAL cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;negative regulation of apoptotic process#GO:0043066;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014944.4|UniProtKB=F7FID8 F7FID8 MED26 PTHR15201:SF1 CRSP70 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000012143.4|UniProtKB=F7DI01 F7DI01 HPD PTHR11959:SF12 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000002010.4|UniProtKB=F7FXT3 F7FXT3 PTHR23197:SF10 TARSH-RELATED FIBRONECTIN DOMAIN-CONTAINING TARGET OF NESH-SH3 molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;animal organ development#GO:0048513;mesenchyme development#GO:0060485;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;mesenchymal cell differentiation#GO:0048762;cell differentiation#GO:0030154;tissue development#GO:0009888;cell development#GO:0048468;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000004634.3|UniProtKB=F6UNM3 F6UNM3 CIBAR2 PTHR21223:SF3 CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN 2 cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;ciliary transition zone#GO:0035869;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000022737.3|UniProtKB=A0A5F8G7K9 A0A5F8G7K9 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000049940.1|UniProtKB=A0A5F8H0G5 A0A5F8H0G5 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005570.4|UniProtKB=A0A5F8H9R2 A0A5F8H9R2 AFF2 PTHR10528:SF18 AF4/FMR2 FAMILY MEMBER AF4_FMR2 FAMILY MEMBER 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 RNA metabolic process#GO:0016070;nervous system process#GO:0050877;nucleic acid biosynthetic process#GO:0141187;regulation of biological process#GO:0050789;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;system process#GO:0003008;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA splicing#GO:0043484;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear speck#GO:0016607;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000010579.4|UniProtKB=F7GI12 F7GI12 DUSP11 PTHR10367:SF18 MRNA-CAPPING ENZYME RNA_RNP COMPLEX-1-INTERACTING PHOSPHATASE catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on RNA#GO:0140098;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 RNA processing factor#PC00147;mRNA capping factor#PC00145 MONDO|Ensembl=ENSMODG00000005248.3|UniProtKB=F6YM83 F6YM83 LOC100019004 PTHR46006:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A NEUROEPITHELIAL CELL-TRANSFORMING GENE 1 PROTEIN positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;positive regulation of cell communication#GO:0010647 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000013578.4|UniProtKB=F7BHV3 F7BHV3 F2RL1 PTHR24232:SF21 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of MAPK cascade#GO:0043410;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002671.4|UniProtKB=F7CYY8 F7CYY8 EHHADH PTHR23309:SF9 3-HYDROXYACYL-COA DEHYROGENASE PEROXISOMAL BIFUNCTIONAL ENZYME oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;microbody#GO:0042579;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000024661.2|UniProtKB=F6Q228 F6Q228 LOC100010036 PTHR26453:SF34 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13C3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002334.4|UniProtKB=F7GLX9 F7GLX9 KLHL2 PTHR24412:SF155 KELCH PROTEIN KELCH-LIKE PROTEIN 2 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000012334.4|UniProtKB=F7E2G1 F7E2G1 HOXB6 PTHR45659:SF9 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-B6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502;anterior/posterior pattern specification#GO:0009952;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000012245.3|UniProtKB=H9H6J6 H9H6J6 INSYN2A PTHR28682:SF1 INHIBITORY SYNAPTIC FACTOR 2A-RELATED INHIBITORY SYNAPTIC FACTOR 2A regulation of biological quality#GO:0065008;cell communication#GO:0007154;nervous system process#GO:0050877;trans-synaptic signaling#GO:0099537;signaling#GO:0023052;chemical synaptic transmission, postsynaptic#GO:0099565;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of postsynaptic membrane potential#GO:0060078;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;system process#GO:0003008;regulation of membrane potential#GO:0042391;cell surface receptor signaling pathway#GO:0007166;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536 postsynapse#GO:0098794;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;postsynaptic density#GO:0014069;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000001357.4|UniProtKB=A0A5F8G7F4 A0A5F8G7F4 PTHR34524:SF2 CALCYPHOSIN CALCYPHOSIN calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000008446.3|UniProtKB=F7GF09 F7GF09 SP5 PTHR23235:SF29 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000001932.4|UniProtKB=A0A5F8GFP3 A0A5F8GFP3 PCSK5 PTHR42884:SF7 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 5 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;hormone metabolic process#GO:0042445;biosynthetic process#GO:0009058;biological regulation#GO:0065007;protein processing#GO:0016485;peptide hormone processing#GO:0016486;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of biological quality#GO:0065008;proteolysis#GO:0006508;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;Alzheimer disease-presenilin pathway#P00004>Furin#P00157 MONDO|Ensembl=ENSMODG00000014371.4|UniProtKB=F6TNB5 F6TNB5 LOC100013884 PTHR23239:SF110 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA7 structural molecule activity#GO:0005198 cytoskeleton organization#GO:0007010;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cellular process#GO:0009987;organelle organization#GO:0006996;morphogenesis of an epithelium#GO:0002009;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;intermediate filament organization#GO:0045109;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000047547.1|UniProtKB=A0A5F8HG02 A0A5F8HG02 PTHR11125:SF7 SUPPRESSOR OF TY 5 TRANSCRIPTION ELONGATION FACTOR SPT5 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000013636.4|UniProtKB=F6UVS3 F6UVS3 PTHR21608:SF6 KINESIN-LIKE PROTEIN CG14535 KINESIN-LIKE PROTEIN KIF26A protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell motility#GO:2000145;regulation of neuron migration#GO:2001222;regulation of cell projection organization#GO:0031344;regulation of cell migration#GO:0030334;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of neuron projection development#GO:0010975;regulation of biological process#GO:0050789 MONDO|Ensembl=ENSMODG00000011784.2|UniProtKB=F7CC74 F7CC74 MTMR10 PTHR10807:SF39 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 10 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000016514.4|UniProtKB=H9H6X7 H9H6X7 ESPL1 PTHR12792:SF3 EXTRA SPINDLE POLES 1-RELATED SEPARIN cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 reproductive process#GO:0022414;cell cycle process#GO:0022402;cell cycle#GO:0007049;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;organelle fission#GO:0048285;sexual reproduction#GO:0019953;nuclear division#GO:0000280;cellular process#GO:0009987;organelle organization#GO:0006996;meiotic chromosome segregation#GO:0045132;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;chromosome separation#GO:0051304;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000024742.2|UniProtKB=F6ZMM5 F6ZMM5 LOC100018766 PTHR45624:SF56 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL CARNITINE_ACYLCARNITINE CARRIER PROTEIN quaternary ammonium group transmembrane transporter activity#GO:0015651;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 mitochondrial transport#GO:0006839;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular transport#GO:0046907;transport#GO:0006810 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000024510.1|UniProtKB=F7AKW5 F7AKW5 LOC100618848 PTHR48002:SF179 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007027.3|UniProtKB=F6UFU6 F6UFU6 PTHR22792:SF166 LUPUS LA PROTEIN-RELATED LUPUS LA PROTEIN HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000008316.3|UniProtKB=F6Q7H1 F6Q7H1 PTHR11829:SF206 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN Q1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000000245.5|UniProtKB=F6RAQ8 F6RAQ8 GLI2 PTHR45718:SF6 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS TRANSCRIPTION ACTIVATOR GLI2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;smoothened signaling pathway#GO:0007224;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Hedgehog signaling pathway#P00025>Cubitus interruptus#P00690 MONDO|Ensembl=ENSMODG00000005171.4|UniProtKB=F7E7S6 F7E7S6 C14orf93 PTHR14375:SF2 SIMILAR TO RIKEN CDNA 4931414P19 SIMILAR TO HUMAN CHROMOSOME 14 OPEN READING FRAME 93 MONDO|Ensembl=ENSMODG00000049547.1|UniProtKB=A0A5F8GHC4 A0A5F8GHC4 NKRF PTHR16148:SF15 NF-KAPPA-B-REPRESSING FACTOR-RELATED NF-KAPPA-B-REPRESSING FACTOR molecular function activator activity#GO:0140677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000008842.3|UniProtKB=A0A5F8GHL0 A0A5F8GHL0 NINJ1 PTHR12316:SF19 NINJURIN-RELATED NINJURIN-1 cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 defense response#GO:0006952;cell adhesion#GO:0007155;inflammatory response#GO:0006954;response to stimulus#GO:0050896;cell death#GO:0008219;cellular process#GO:0009987;response to stress#GO:0006950;programmed cell death#GO:0012501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000046248.1|UniProtKB=A0A5F8H1S8 A0A5F8H1S8 LOC100013022 PTHR26453:SF0 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13D1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016819.4|UniProtKB=A0A5F8G8H7 A0A5F8G8H7 KATNA1 PTHR23074:SF71 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A1 catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000010294.4|UniProtKB=A0A5F8H5E6 A0A5F8H5E6 PTHR11523:SF12 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT PROTEIN ATP1B4 ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 export from cell#GO:0140352;import across plasma membrane#GO:0098739;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;import into cell#GO:0098657;chemical homeostasis#GO:0048878;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;monoatomic cation transport#GO:0006812;localization#GO:0051179;potassium ion homeostasis#GO:0055075;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;intracellular chemical homeostasis#GO:0055082;regulation of gene expression#GO:0010468;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;plasma membrane#GO:0005886;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;organelle inner membrane#GO:0019866;transporter complex#GO:1990351;organelle membrane#GO:0031090;nuclear inner membrane#GO:0005637;nuclear membrane#GO:0031965;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000013667.3|UniProtKB=F6TXD9 F6TXD9 ADSSL1 PTHR11846:SF2 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE ISOZYME 1 ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;primary metabolic process#GO:0044238;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;IMP metabolic process#GO:0046040;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside phosphate biosynthetic process#GO:1901293 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;ligase#PC00142 De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890;Wnt signaling pathway#P00057>NFAT Target Genes#G01559 MONDO|Ensembl=ENSMODG00000017689.4|UniProtKB=F6QJW9 F6QJW9 MACF1 PTHR23169:SF25 ENVOPLAKIN MICROTUBULE-ACTIN CROSS-LINKING FACTOR 1, ISOFORMS 1_2_3_4_5 biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;cytoskeleton organization#GO:0007010;regulation of cell adhesion#GO:0030155;cellular process#GO:0009987;response to wounding#GO:0009611;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;intermediate filament cytoskeleton organization#GO:0045104;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;wound healing#GO:0042060;regulation of cell-matrix adhesion#GO:0001952;regulation of cell junction assembly#GO:1901888;regulation of microtubule-based process#GO:0032886;intermediate filament-based process#GO:0045103 supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 intermediate filament#PC00129;intermediate filament binding protein#PC00130 MONDO|Ensembl=ENSMODG00000012368.4|UniProtKB=A0A5F8GNF4 A0A5F8GNF4 CBX1 PTHR22812:SF159 CHROMOBOX PROTEIN CHROMOBOX 1 binding#GO:0005488;chromatin binding#GO:0003682 heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;cellular component assembly#GO:0022607;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;chromosome#GO:0005694;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775 MONDO|Ensembl=ENSMODG00000004098.4|UniProtKB=K7E106 K7E106 PRPF31 PTHR13904:SF0 PRE-MRNA SPLICING FACTOR PRP31 U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000013198.3|UniProtKB=F7FA62 F7FA62 PTHR45776:SF1 MIP04163P TRANSCRIPTION FACTOR EC sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000008231.4|UniProtKB=F6W6U6 F6W6U6 FGD6 PTHR12673:SF12 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 6 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000016091.3|UniProtKB=F6PL30 F6PL30 TBL3 PTHR19854:SF15 TRANSDUCIN BETA-LIKE 3 TRANSDUCIN BETA-LIKE PROTEIN 3 RNA binding#GO:0003723;U3 snoRNA binding#GO:0034511;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000003719.3|UniProtKB=F7EWC9 F7EWC9 SIAE PTHR22901:SF0 SIALATE O-ACETYLESTERASE SIALATE O-ACETYLESTERASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 carbohydrate metabolic process#GO:0005975;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 hydrolase#PC00121;esterase#PC00097 MONDO|Ensembl=ENSMODG00000017077.5|UniProtKB=F7E0N9 F7E0N9 ENTREP3 PTHR17615:SF7 PROTEIN FAM189A PROTEIN ENTREP3 MONDO|Ensembl=ENSMODG00000024527.2|UniProtKB=F6ZW75 F6ZW75 PTHR13218:SF8 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933 intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669 general transcription factor#PC00259;RNA metabolism protein#PC00031 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 MONDO|Ensembl=ENSMODG00000007909.4|UniProtKB=F7GIJ1 F7GIJ1 ZNF143 PTHR24388:SF55 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 143 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000049867.1|UniProtKB=A0A5F8G5Y0 A0A5F8G5Y0 VN2R634 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000023959.1|UniProtKB=F6ZFS9 F6ZFS9 TMEM30B PTHR10926:SF19 CELL CYCLE CONTROL PROTEIN 50 CELL CYCLE CONTROL PROTEIN 50B protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;biological regulation#GO:0065007;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035 cell periphery#GO:0071944;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000011291.4|UniProtKB=F6WZ70 F6WZ70 DEK PTHR13468:SF24 DEK PROTEIN PROTEIN DEK binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of double-strand break repair#GO:2000779;regulation of cellular response to stress#GO:0080135;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000006511.2|UniProtKB=F7EJV7 F7EJV7 PTHR28653:SF1 FAMILY NOT NAMED ATPASE SWSAP1 MONDO|Ensembl=ENSMODG00000012892.4|UniProtKB=F7ACA7 F7ACA7 OR8D4 PTHR48018:SF137 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8D4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015026.2|UniProtKB=F7BXE3 F7BXE3 PTHR43511:SF4 FAMILY NOT NAMED UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE MONDO|Ensembl=ENSMODG00000003291.3|UniProtKB=F7EG17 F7EG17 PTHR18874:SF10 CMF/LEK/CENP CELL DIVISION-RELATED CENTROMERE PROTEIN F MONDO|Ensembl=ENSMODG00000015025.4|UniProtKB=F7BXF2 F7BXF2 CLK1 PTHR45646:SF4 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED DUAL SPECIFICITY PROTEIN KINASE CLK1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740 biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000017819.5|UniProtKB=F6ZXM6 F6ZXM6 GPRC6A PTHR24061:SF5 CALCIUM-SENSING RECEPTOR-RELATED G PROTEIN-COUPLED RECEPTOR FAMILY C GROUP 6 MEMBER A G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005729.4|UniProtKB=F6QEG4 F6QEG4 ALPK1 PTHR46747:SF1 ALPHA-PROTEIN KINASE 1 ALPHA-PROTEIN KINASE 1 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000005124.3|UniProtKB=F7F5Q3 F7F5Q3 FCER1G PTHR16803:SF0 HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR GAMMA-SUBUNIT HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT GAMMA signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune system process#GO:0002376;defense response to other organism#GO:0098542;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;response to other organism#GO:0051707;adaptive immune response#GO:0002250;immune response#GO:0006955;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;regulation of response to stimulus#GO:0048583 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000004851.3|UniProtKB=F6U4M8 F6U4M8 ZNF518A PTHR24392:SF39 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 518A transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000003976.4|UniProtKB=A0A5F8H163 A0A5F8H163 GALNS PTHR42693:SF47 ARYLSULFATASE FAMILY MEMBER N-ACETYLGALACTOSAMINE-6-SULFATASE hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000003936.4|UniProtKB=A0A5F8G6K3 A0A5F8G6K3 ELAVL2 PTHR10352:SF12 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 2 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 MONDO|Ensembl=ENSMODG00000037153.1|UniProtKB=A0A5F8HE97 A0A5F8HE97 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000050179.1|UniProtKB=A0A5F8H6J3 A0A5F8H6J3 GSX2 PTHR47421:SF1 GS HOMEOBOX 2 GS HOMEOBOX 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000019740.4|UniProtKB=A0A5F8GCV1 A0A5F8GCV1 PDE8B PTHR11347:SF98 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8B catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;cyclic-nucleotide phosphodiesterase activity#GO:0004112 negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;positive regulation of signal transduction#GO:0009967;negative regulation of cell communication#GO:0010648;positive regulation of signaling#GO:0023056;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057 hydrolase#PC00121;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000020833.3|UniProtKB=F6RL76 F6RL76 PTHR32341:SF18 INTERFERON-INDUCIBLE GTPASE IRG-TYPE G DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 MONDO|Ensembl=ENSMODG00000036505.1|UniProtKB=A0A5F8GFF3 A0A5F8GFF3 DPM2 PTHR15039:SF11 DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mannosyltransferase complex#GO:0031501;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000012631.3|UniProtKB=F6WU96 F6WU96 SPMAP1 PTHR34221:SF2 HYPOTHETICAL PROTEIN LOC691189 SPERM MICROTUBULE ASSOCIATED PROTEIN 1 MONDO|Ensembl=ENSMODG00000013267.3|UniProtKB=F7D9I7 F7D9I7 HINFP PTHR24391:SF26 HISTONE H4 TRANSCRIPTION FACTOR-RELATED HISTONE H4 TRANSCRIPTION FACTOR RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000001327.4|UniProtKB=A0A5F8GGB5 A0A5F8GGB5 PJA2 PTHR15710:SF261 E3 UBIQUITIN-PROTEIN LIGASE PRAJA RING-TYPE E3 UBIQUITIN TRANSFERASE positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of response to stimulus#GO:0048584;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000006971.4|UniProtKB=F6QUS5 F6QUS5 PTHR13452:SF10 THUMP DOMAIN CONTAINING PROTEIN 1-RELATED THUMP DOMAIN-CONTAINING PROTEIN 1 protein-RNA adaptor activity#GO:0140517;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 MONDO|Ensembl=ENSMODG00000008151.3|UniProtKB=A0A5F8GT09 A0A5F8GT09 WDR45 PTHR11227:SF29 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 4 protein-macromolecule adaptor activity#GO:0030674;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981 carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;vacuole organization#GO:0007033;localization#GO:0051179;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;macroautophagy#GO:0016236;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052;cellular component assembly#GO:0022607;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;phagophore assembly site#GO:0000407;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000023968.3|UniProtKB=F7F6L4 F7F6L4 ZCWPW2 PTHR15999:SF6 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 2 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000016206.2|UniProtKB=F7FY27 F7FY27 LOC100029846 PTHR12126:SF11 NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL protein-containing complex binding#GO:0044877;binding#GO:0005488 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;ketone metabolic process#GO:0042180 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000047883.1|UniProtKB=A0A5F8GNF9 A0A5F8GNF9 LOC100023754 PTHR12612:SF48 NUCLEAR TRANSPORT FACTOR 2 NUCLEAR TRANSPORT FACTOR 2 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234 nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000007245.4|UniProtKB=F6WBF3 F6WBF3 TTC5 PTHR26312:SF87 TETRATRICOPEPTIDE REPEAT PROTEIN 5 TETRATRICOPEPTIDE REPEAT PROTEIN 5 MONDO|Ensembl=ENSMODG00000016105.4|UniProtKB=F7EAZ8 F7EAZ8 C1QC PTHR15427:SF29 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q SUBCOMPONENT SUBUNIT C molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;regulation of immune response#GO:0050776;immune system process#GO:0002376;adaptive immune response#GO:0002250;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;complement activation#GO:0006956;immune response#GO:0006955;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;humoral immune response#GO:0006959 membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;glutamatergic synapse#GO:0098978;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;extracellular protein-containing complex#GO:0140392;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;cellular anatomical structure#GO:0110165;synapse#GO:0045202;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000025362.2|UniProtKB=F7DKB3 F7DKB3 RAB9A PTHR47981:SF9 RAB FAMILY RAS-RELATED PROTEIN RAB-9A molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;cellular component biogenesis#GO:0044085;membrane fusion#GO:0061025;retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;lysosome organization#GO:0007040;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;endosomal transport#GO:0016197;intracellular transport#GO:0046907;phagocytosis#GO:0006909;phagolysosome assembly#GO:0001845;lytic vacuole organization#GO:0080171;transport#GO:0006810;endocytosis#GO:0006897;cytosolic transport#GO:0016482;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;vacuole organization#GO:0007033;organelle assembly#GO:0070925 vacuole#GO:0005773;cytoplasm#GO:0005737;late endosome#GO:0005770;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;lytic vacuole#GO:0000323;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000017868.4|UniProtKB=A0A5F8GWD3 A0A5F8GWD3 TTBK2 PTHR11909:SF451 CASEIN KINASE-RELATED TAU-TUBULIN KINASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular process#GO:0009987;cell projection assembly#GO:0030031;signal transduction#GO:0007165;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cilium assembly#GO:0060271;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell projection organization#GO:0030030;organelle assembly#GO:0070925;cilium organization#GO:0044782;cell communication#GO:0007154 microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;ciliary transition zone#GO:0035869;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000025633.2|UniProtKB=F6XWD9 F6XWD9 PTHR12560:SF6 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 4 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;ceramide metabolic process#GO:0006672 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000005265.5|UniProtKB=F7GGQ5 F7GGQ5 IL17RE PTHR15583:SF5 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR E immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to peptide#GO:1901652;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;cell communication#GO:0007154;positive regulation of macromolecule biosynthetic process#GO:0010557;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;response to cytokine#GO:0034097;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012376.4|UniProtKB=F6Z758 F6Z758 PTHR10751:SF141 GUANYLATE BINDING PROTEIN GB1_RHD3-TYPE G DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 G-protein#PC00020;heterotrimeric G-protein#PC00117 MONDO|Ensembl=ENSMODG00000051088.1|UniProtKB=A0A5F8H7K3 A0A5F8H7K3 LOC103101841 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004543.2|UniProtKB=F6R5N7 F6R5N7 PPP1R3E PTHR12307:SF20 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3E polysaccharide binding#GO:0030247;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899;carbohydrate binding#GO:0030246;protein binding#GO:0005515;protein phosphatase binding#GO:0019903 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of polysaccharide metabolic process#GO:0032881;regulation of carbohydrate biosynthetic process#GO:0043255;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of glycogen biosynthetic process#GO:0005979;regulation of carbohydrate metabolic process#GO:0006109;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000042412.1|UniProtKB=A0A5F8HKD8 A0A5F8HKD8 CNRIP1 PTHR31952:SF1 CB1 CANNABINOID RECEPTOR-INTERACTING PROTEIN 1 CB1 CANNABINOID RECEPTOR-INTERACTING PROTEIN 1 G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000024114.2|UniProtKB=F6V606 F6V606 LOC100028573 PTHR10877:SF185 POLYCYSTIN FAMILY MEMBER POLYCYSTIN FAMILY RECEPTOR FOR EGG JELLY monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873 response to mechanical stimulus#GO:0009612;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;detection of mechanical stimulus#GO:0050982;response to external stimulus#GO:0009605;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000050149.1|UniProtKB=A0A5F8GL68 A0A5F8GL68 NDUFB1 PTHR15222:SF2 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 1 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 1 respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000044053.1|UniProtKB=A0A5F8H5Q3 A0A5F8H5Q3 HOXB7 PTHR45659:SF11 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-B7 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000037663.1|UniProtKB=F6QLK8 F6QLK8 LOC103100301 PTHR48001:SF39 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003463.3|UniProtKB=F7DCC2 F7DCC2 PTHR12047:SF2 FANCONI ANEMIA GROUP A PROTEIN FANCONI ANEMIA GROUP A PROTEIN regulation of cell development#GO:0060284;regulation of cell activation#GO:0050865;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694;regulation of lymphocyte activation#GO:0051249;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of T cell activation#GO:0050863;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell differentiation#GO:0045595;regulation of hemopoiesis#GO:1903706 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Fanconi anaemia nuclear complex#GO:0043240;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000006997.4|UniProtKB=F6XVJ9 F6XVJ9 RNASEH2A PTHR10954:SF7 RIBONUCLEASE H2 SUBUNIT A RIBONUCLEASE H2 SUBUNIT A hydrolase activity#GO:0016787;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;mismatch repair#GO:0006298;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 endoribonuclease#PC00094 DNA replication#P00017>RNase H#P00538 MONDO|Ensembl=ENSMODG00000019087.4|UniProtKB=F7FND3 F7FND3 RUFY3 PTHR45956:SF1 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN PROTEIN RUFY3 regulation of biological process#GO:0050789;regulation of neuron projection development#GO:0010975;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cell projection organization#GO:0031344;regulation of axonogenesis#GO:0050770;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035 neuron projection#GO:0043005;cell body#GO:0044297;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000005111.3|UniProtKB=F6YQC5 F6YQC5 TOMM40L PTHR10802:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40B transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179 mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane translocase complex#GO:0005742;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000019184.4|UniProtKB=F7AWK0 F7AWK0 LOC100618318 PTHR12015:SF201 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 6 cytokine activity#GO:0005125;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 response to other organism#GO:0051707;cell migration#GO:0016477;immune response#GO:0006955;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;cellular response to molecule of bacterial origin#GO:0071219;leukocyte migration#GO:0050900;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;cell motility#GO:0048870;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;cell chemotaxis#GO:0060326;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;chemotaxis#GO:0006935;inflammatory response#GO:0006954;response to bacterium#GO:0009617;taxis#GO:0042330;neutrophil migration#GO:1990266;response to chemical#GO:0042221;granulocyte migration#GO:0097530;cellular response to lipid#GO:0071396;defense response to other organism#GO:0098542;response to lipid#GO:0033993;cellular response to oxygen-containing compound#GO:1901701;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to lipopolysaccharide#GO:0032496;neutrophil chemotaxis#GO:0030593;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;response to molecule of bacterial origin#GO:0002237;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 MONDO|Ensembl=ENSMODG00000021480.2|UniProtKB=F7G367 F7G367 CLUL1 PTHR10970:SF2 CLUSTERIN CLUSTERIN-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000002561.5|UniProtKB=F7F5W4 F7F5W4 TRIM72 PTHR24103:SF11 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 72 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 protein metabolic process#GO:0019538;immune system process#GO:0002376;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;defense response to other organism#GO:0098542;response to other organism#GO:0051707;proteasomal protein catabolic process#GO:0010498;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;sarcolemma#GO:0042383;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000020855.4|UniProtKB=F6R0D1 F6R0D1 RELB PTHR24169:SF18 NUCLEAR FACTOR NF-KAPPA-B PROTEIN TRANSCRIPTION FACTOR RELB cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;response to other organism#GO:0051707;canonical NF-kappaB signal transduction#GO:0007249;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;cellular response to stimulus#GO:0051716;response to external biotic stimulus#GO:0043207;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;non-canonical NF-kappaB signal transduction#GO:0038061;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;intracellular signaling cassette#GO:0141124;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;defense response to other organism#GO:0098542;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biological process#GO:0050789;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;immune system process#GO:0002376;response to peptide#GO:1901652;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;gene-specific transcriptional regulator#PC00264 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Apoptosis signaling pathway#P00006>NFkappaB#P00297 MONDO|Ensembl=ENSMODG00000012075.3|UniProtKB=F7G4Z8 F7G4Z8 C19orf67 PTHR36292:SF1 UPF0575 PROTEIN C19ORF67 UPF0575 PROTEIN C19ORF67 MONDO|Ensembl=ENSMODG00000012764.3|UniProtKB=F6SIR7 F6SIR7 GAL PTHR16839:SF1 GALANIN GALANIN PEPTIDES neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cell body#GO:0044297;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;neuronal cell body#GO:0043025;secretory vesicle#GO:0099503;endomembrane system#GO:0012505;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477 MONDO|Ensembl=ENSMODG00000008291.4|UniProtKB=F7FU03 F7FU03 GGH PTHR11315:SF20 PROTEASE FAMILY C26 GAMMA-GLUTAMYL HYDROLASE GAMMA-GLUTAMYL HYDROLASE catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000041005.1|UniProtKB=F6UEN4 F6UEN4 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000006339.3|UniProtKB=K7E4M7 K7E4M7 IMPA1 PTHR20854:SF26 INOSITOL MONOPHOSPHATASE INOSITOL MONOPHOSPHATASE 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;biosynthetic process#GO:0009058;biological regulation#GO:0065007;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000005735.3|UniProtKB=A0ACM8QJQ4 A0ACM8QJQ4 HMGB3 PTHR48112:SF43 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B3 chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 MONDO|Ensembl=ENSMODG00000007035.5|UniProtKB=F6UFR1 F6UFR1 USH1G PTHR24161:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PRE-MRNA SPLICING REGULATOR USH1G multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;system process#GO:0003008;sensory perception of light stimulus#GO:0050953;nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600 membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;photoreceptor inner segment#GO:0001917;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;9+0 non-motile cilium#GO:0097731;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000039581.1|UniProtKB=A0A5F8G9Z8 A0A5F8G9Z8 RIMOC1 PTHR28494:SF1 UPF0600 PROTEIN C5ORF51 RAB7A-INTERACTING MON1-CCZ1 COMPLEX SUBUNIT 1 MONDO|Ensembl=ENSMODG00000007489.4|UniProtKB=F7CQM5 F7CQM5 TOGARAM1 PTHR21567:SF6 CLASP TOG ARRAY REGULATOR OF AXONEMAL MICROTUBULES PROTEIN 1 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000047797.1|UniProtKB=A0A5F8GC17 A0A5F8GC17 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009952.4|UniProtKB=F7FLH1 F7FLH1 PLEKHH1 PTHR22903:SF4 PLEKHH PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 1 MONDO|Ensembl=ENSMODG00000019875.4|UniProtKB=F6WL38 F6WL38 SYT13 PTHR10024:SF250 SYNAPTOTAGMIN SYNAPTOTAGMIN-13 SNARE binding#GO:0000149;phospholipid binding#GO:0005543;binding#GO:0005488;protein binding#GO:0005515;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;positive regulation of cellular process#GO:0048522;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;regulation of exocytosis#GO:0017157;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;vesicle-mediated transport in synapse#GO:0099003;regulation of localization#GO:0032879;regulation of transport#GO:0051049;positive regulation of vesicle fusion#GO:0031340;exocytosis#GO:0006887;regulated exocytosis#GO:0045055;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;synaptic vesicle exocytosis#GO:0016079;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;cellular process#GO:0009987;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;regulation of neurotransmitter transport#GO:0051588;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;regulation of neurotransmitter secretion#GO:0046928;signaling#GO:0023052;export from cell#GO:0140352;regulation of synaptic vesicle exocytosis#GO:2000300;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;cell projection#GO:0042995;intracellular vesicle#GO:0097708;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;neuron projection#GO:0043005;presynapse#GO:0098793;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;axon#GO:0030424;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;organelle membrane#GO:0031090;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000004568.3|UniProtKB=F6R4T8 F6R4T8 NTAN1 PTHR12498:SF0 N-TERMINAL ASPARAGINE AMIDOHYDROLASE PROTEIN N-TERMINAL ASPARAGINE AMIDOHYDROLASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000013094.4|UniProtKB=F7EXN1 F7EXN1 RAPGEFL1 PTHR23113:SF230 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR-LIKE 1 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000012105.4|UniProtKB=F7FUE5 F7FUE5 FUBP3 PTHR10288:SF234 KH DOMAIN CONTAINING RNA BINDING PROTEIN FAR UPSTREAM ELEMENT-BINDING PROTEIN 3 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000005196.4|UniProtKB=F7A295 F7A295 PWWP3A PTHR31333:SF6 PWWP DOMAIN-CONTAINING DNA REPAIR FACTOR 3 FAMILY MEMBER MUM1 LIKE 1 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000007628.3|UniProtKB=F7BL42 F7BL42 CALB1 PTHR19972:SF14 CALBINDIN CALBINDIN calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron projection terminus#GO:0044306;cell projection#GO:0042995;distal axon#GO:0150034;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;dendrite#GO:0030425;intracellular organelle#GO:0043229;axon#GO:0030424;dendritic tree#GO:0097447;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;neuron projection#GO:0043005;presynapse#GO:0098793;nucleus#GO:0005634;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;cell junction#GO:0030054;axon terminus#GO:0043679 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000041931.1|UniProtKB=A0A5F8GG53 A0A5F8GG53 LOC100032457 PTHR11482:SF57 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE GENE MODEL 853, (NCBI) carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;ornithine decarboxylase activity#GO:0004586;lyase activity#GO:0016829 regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;polyamine metabolic process#GO:0006595;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of catabolic process#GO:0009894;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;amine metabolic process#GO:0009308;regulation of primary metabolic process#GO:0080090;biogenic amine metabolic process#GO:0006576;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of protein catabolic process#GO:0042177;polyamine biosynthetic process#GO:0006596 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000043340.1|UniProtKB=A0A5F8HIU9 A0A5F8HIU9 LOC100014842 PTHR23226:SF420 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 956 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000049471.1|UniProtKB=A0A5F8HH20 A0A5F8HH20 PTHR13581:SF5 MRG-BINDING PROTEIN MRG_MORF4L-BINDING PROTEIN regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000015659.3|UniProtKB=H9H6S0 H9H6S0 PTHR24064:SF34 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 20 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000048786.1|UniProtKB=A0A5F8HIB2 A0A5F8HIB2 PTHR21553:SF22 ALMS1-RELATED CENTROSOME-ASSOCIATED PROTEIN ALMS1 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;regulation of organelle organization#GO:0033043;regulation of organelle assembly#GO:1902115;regulation of biological process#GO:0050789;regulation of microtubule-based process#GO:0032886 microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000009085.4|UniProtKB=F7FQT9 F7FQT9 BMI1 PTHR10825:SF21 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB COMPLEX PROTEIN BMI-1 chromatin binding#GO:0003682;binding#GO:0005488 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605 organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000004596.1|UniProtKB=F6QIS0 F6QIS0 EMC8 PTHR12941:SF13 ER MEMBRANE PROTEIN COMPLEX ER MEMBRANE PROTEIN COMPLEX SUBUNIT 8 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048 cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;EMC complex#GO:0072546;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000000329.4|UniProtKB=F6VDQ3 F6VDQ3 PKP1 PTHR10372:SF3 PLAKOPHILLIN-RELATED PLAKOPHILIN-1 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;cell junction#GO:0030054;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;intracellular organelle#GO:0043229 intermediate filament#PC00129;cytoskeletal protein#PC00085;intermediate filament binding protein#PC00130 MONDO|Ensembl=ENSMODG00000036910.1|UniProtKB=A0A5F8HCN9 A0A5F8HCN9 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000049394.1|UniProtKB=A0A5F8H2G4 A0A5F8H2G4 PTHR24256:SF521 TRYPTASE-RELATED TRYPTASE DELTA serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000016756.4|UniProtKB=F6YL12 F6YL12 FBXL16 PTHR13318:SF193 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 16 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000008158.4|UniProtKB=A0A5F8GI21 A0A5F8GI21 MAP7D2 PTHR15073:SF3 MICROTUBULE-ASSOCIATED PROTEIN MAP7 DOMAIN-CONTAINING PROTEIN 2 cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule bundle formation#GO:0001578;regulation of microtubule-based process#GO:0032886 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000011360.2|UniProtKB=F6T5B8 F6T5B8 GJC1 PTHR11984:SF6 CONNEXIN GAP JUNCTION GAMMA-1 PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 cellular process#GO:0009987;regulation of biological process#GO:0050789;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell junction#GO:0030054 gap junction#PC00105;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000012753.4|UniProtKB=F6T058 F6T058 GALNT12 PTHR11675:SF18 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 12 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000047857.1|UniProtKB=A0A5F8GUM0 A0A5F8GUM0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000023196.2|UniProtKB=F7EUC1 F7EUC1 PTHR23004:SF9 DOUBLECORTIN DOMAIN CONTAINING 2 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 2C cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000010518.4|UniProtKB=F7DR54 F7DR54 FANK1 PTHR24183:SF1 FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1 FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000005770.2|UniProtKB=F6XYX9 F6XYX9 PTHR45701:SF6 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 3 binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484;protein binding#GO:0005515 cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;vesicle fusion#GO:0006906;localization#GO:0051179;membrane fusion#GO:0061025;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933 intracellular anatomical structure#GO:0005622;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944 membrane traffic protein#PC00150 Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423 MONDO|Ensembl=ENSMODG00000000137.4|UniProtKB=F6YAY2 F6YAY2 SMIM20 PTHR34923:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 20 SMALL INTEGRAL MEMBRANE PROTEIN 20 mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866 MONDO|Ensembl=ENSMODG00000006310.4|UniProtKB=F7BR05 F7BR05 AHCTF1 PTHR21583:SF8 ELYS PROTEIN PROTEIN ELYS scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000036403.1|UniProtKB=A0A5F8H3X1 A0A5F8H3X1 PTHR24034:SF87 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBULIN 7 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000000432.4|UniProtKB=F6UT79 F6UT79 HHIP PTHR19328:SF27 HEDGEHOG-INTERACTING PROTEIN HEDGEHOG-INTERACTING PROTEIN protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000000328.4|UniProtKB=F6VDR5 F6VDR5 SLC34A2 PTHR10010:SF23 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B symporter activity#GO:0015293;phosphate transmembrane transporter activity#GO:0005315;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081 intracellular chemical homeostasis#GO:0055082;inorganic anion transport#GO:0015698;cellular homeostasis#GO:0019725;localization#GO:0051179;establishment of localization#GO:0051234;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592;phosphate ion transport#GO:0006817 apical part of cell#GO:0045177;cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;cell periphery#GO:0071944;brush border#GO:0005903;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;organelle#GO:0043226;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000013439.4|UniProtKB=F7G9W3 F7G9W3 IFT46 PTHR13376:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 46 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 46 HOMOLOG microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cilium assembly#GO:0060271;cellular component organization#GO:0016043 microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intraciliary transport particle B#GO:0030992;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000022908.2|UniProtKB=F6Q040 F6Q040 OR51B6 PTHR26450:SF22 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51B6 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005642.3|UniProtKB=F7BWC2 F7BWC2 RBBP9 PTHR15394:SF3 SERINE HYDROLASE RBBP9 SERINE HYDROLASE RBBP9 MONDO|Ensembl=ENSMODG00000042701.1|UniProtKB=A0A5F8H0P7 A0A5F8H0P7 RPS27L PTHR11594:SF2 40S RIBOSOMAL PROTEIN S27 RIBOSOMAL PROTEIN ES27-LIKE structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;protein biosynthetic process#GO:0160307;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000024063.3|UniProtKB=F7G6M0 F7G6M0 PTHR16675:SF289 MHC CLASS I-RELATED ZINC-ALPHA-2-GLYCOPROTEIN regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000013656.4|UniProtKB=F6XI44 F6XI44 DNTTIP1 PTHR23399:SF2 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;chromatin-protein adaptor activity#GO:0140463 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000006723.4|UniProtKB=A0A5F8GM68 A0A5F8GM68 DNAI2 PTHR12442:SF7 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 2 binding#GO:0005488;protein binding#GO:0005515 axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cilium movement#GO:0003341;organelle assembly#GO:0070925;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cilium assembly#GO:0060271;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;cilium#GO:0005929;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;dynein complex#GO:0030286;axonemal dynein complex#GO:0005858;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;outer dynein arm#GO:0036157;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000011543.4|UniProtKB=F6QWT8 F6QWT8 GRN PTHR12274:SF9 GRANULIN PROGRANULIN regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000005698.3|UniProtKB=F6UK18 F6UK18 R3HDM4 PTHR32019:SF2 R3H DOMAIN-CONTAINING PROTEIN 4 R3H DOMAIN-CONTAINING PROTEIN 4 MONDO|Ensembl=ENSMODG00000036826.1|UniProtKB=A0A5F8H690 A0A5F8H690 RSL24D1 PTHR10792:SF8 60S RIBOSOMAL PROTEIN L24 RIBOSOME BIOGENESIS PROTEIN RLP24-RELATED ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000036668.1|UniProtKB=A0A5F8HI48 A0A5F8HI48 PTHR45882:SF4 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>PITX#P06722 MONDO|Ensembl=ENSMODG00000024816.2|UniProtKB=F6XC65 F6XC65 PTHR23087:SF12 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-14 chromatin binding#GO:0003682;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000002096.4|UniProtKB=F6UHB8 F6UHB8 PTHR11909:SF100 CASEIN KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE VRK2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cell communication#GO:0007154 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000016880.2|UniProtKB=A0A5F8GLL0 A0A5F8GLL0 PTHR13362:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S33 SMALL RIBOSOMAL SUBUNIT PROTEIN MS33 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000045590.1|UniProtKB=F6V6K9 F6V6K9 LOC100019025 PTHR48002:SF63 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024331.2|UniProtKB=Q2AB88 Q2AB88 TAS2R39 PTHR11394:SF142 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 39 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of taste#GO:0050909;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012111.4|UniProtKB=F7FUD3 F7FUD3 TMEM120B PTHR21433:SF2 TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA TRANSMEMBRANE PROTEIN 120B cellular process#GO:0009987;developmental process#GO:0032502;fat cell differentiation#GO:0045444;cellular developmental process#GO:0048869;cell differentiation#GO:0030154 organelle inner membrane#GO:0019866;nucleus#GO:0005634;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;nuclear membrane#GO:0031965;membrane-bounded organelle#GO:0043227;nuclear inner membrane#GO:0005637 MONDO|Ensembl=ENSMODG00000001078.4|UniProtKB=F7GHW6 F7GHW6 MYH9 PTHR45615:SF16 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-9 polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000046742.1|UniProtKB=A0A5F8GYL1 A0A5F8GYL1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000002962.3|UniProtKB=A0A5F8HLK5 A0A5F8HLK5 CBLN3 PTHR22923:SF2 CEREBELLIN-RELATED CEREBELLIN-3 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010440.5|UniProtKB=A0A5F8HHR7 A0A5F8HHR7 CFAP69 PTHR14716:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69 positive regulation of cell motility#GO:2000147;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;regulation of microtubule-based movement#GO:0060632;regulation of reproductive process#GO:2000241;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of microtubule-based process#GO:0032886;regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017 membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cilium#GO:0005929;9+2 motile cilium#GO:0097729;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000008494.4|UniProtKB=F7FTT0 F7FTT0 USP47 PTHR24006:SF702 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 47 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000024076.5|UniProtKB=F7CI47 F7CI47 SNX15 PTHR15508:SF9 RIBOSOMAL PROTEIN S6 KINASE SORTING NEXIN-15 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000050877.1|UniProtKB=A0A5F8H7C9 A0A5F8H7C9 LOC100023178 PTHR26453:SF33 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017350.4|UniProtKB=F6WEX7 F6WEX7 MSL3 PTHR10880:SF55 MORTALITY FACTOR 4-LIKE PROTEIN MSL COMPLEX SUBUNIT 3 chromatin binding#GO:0003682;histone reader activity#GO:0140566;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000046353.1|UniProtKB=A0A5F8G959 A0A5F8G959 LOC100024383 PTHR11394:SF49 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 3 transmembrane signaling receptor activity#GO:0004888;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527 detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013188.3|UniProtKB=F7FAD2 F7FAD2 THY1 PTHR19226:SF2 THY-1 MEMBRANE GLYCOPROTEIN THY-1 MEMBRANE GLYCOPROTEIN enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;regulation of cell adhesion#GO:0030155;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811;integrin-mediated signaling pathway#GO:0007229;cell communication#GO:0007154;regulation of cell-matrix adhesion#GO:0001952;positive regulation of cellular component organization#GO:0051130;regulation of cell junction assembly#GO:1901888 dendritic tree#GO:0097447;membrane microdomain#GO:0098857;external side of plasma membrane#GO:0009897;dendrite#GO:0030425;side of membrane#GO:0098552;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;membrane raft#GO:0045121;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000003362.2|UniProtKB=F6ZPT8 F6ZPT8 CYRIA PTHR12422:SF4 GH09096P CYFIP-RELATED RAC1 INTERACTOR A MONDO|Ensembl=ENSMODG00000040189.1|UniProtKB=A0A5F8HFZ6 A0A5F8HFZ6 CLN5 PTHR15380:SF2 CEROID-LIPOFUSCINOSIS, NEURONAL 5 BIS(MONOACYLGLYCERO)PHOSPHATE SYNTHASE CLN5 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular component organization#GO:0016043;organelle organization#GO:0006996;lytic vacuole organization#GO:0080171;cellular process#GO:0009987;lysosome organization#GO:0007040;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033 vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;lysosomal membrane#GO:0005765;cytoplasm#GO:0005737;vacuole#GO:0005773;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000008136.4|UniProtKB=A0A5F8GGG9 A0A5F8GGG9 RFX7 PTHR12619:SF2 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX7 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000047596.1|UniProtKB=A0A5F8HH00 A0A5F8HH00 PTHR45808:SF4 RHO GTPASE-ACTIVATING PROTEIN 68F RHO GTPASE-ACTIVATING PROTEIN 8 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 signaling#GO:0023052;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 VEGF signaling pathway#P00056>Rac#P01421;PDGF signaling pathway#P00047>Rho#P01174;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520;Angiogenesis#P00005>Rac#P00245 MONDO|Ensembl=ENSMODG00000049612.1|UniProtKB=A0A5F8GAB5 A0A5F8GAB5 WARS2 PTHR43766:SF5 TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;translation#GO:0006412;mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial RNA metabolic process#GO:0000959 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000009577.4|UniProtKB=F7AWE1 F7AWE1 HOXD10 PTHR45874:SF5 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN HOX-D10 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000007034.3|UniProtKB=F7E387 F7E387 PTHR11437:SF69 RIBONUCLEASE RIBONUCLEASE A-DOMAIN DOMAIN-CONTAINING PROTEIN nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 RNA metabolism protein#PC00031;endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000043258.1|UniProtKB=A0A5F8GK41 A0A5F8GK41 PRR5 PTHR32428:SF4 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT BIT61-RELATED PROLINE-RICH PROTEIN 5 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;TORC2 signaling#GO:0038203;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;TOR signaling#GO:0031929;positive regulation of response to stimulus#GO:0048584 intracellular protein-containing complex#GO:0140535;TOR complex#GO:0038201;protein-containing complex#GO:0032991 PDGF signaling pathway#P00047>Rho#P01174;VEGF signaling pathway#P00056>Rac#P01421;Angiogenesis#P00005>Rac#P00245;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520 MONDO|Ensembl=ENSMODG00000014913.4|UniProtKB=A0A5F8G671 A0A5F8G671 CCDC171 PTHR47899:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 171 COILED-COIL DOMAIN-CONTAINING PROTEIN 171 MONDO|Ensembl=ENSMODG00000015052.4|UniProtKB=F7FUK8 F7FUK8 SKIC2 PTHR12131:SF34 ATP-DEPENDENT RNA AND DNA HELICASE SUPERKILLER COMPLEX PROTEIN 2 macromolecular conformation isomerase activity#GO:0120543;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657 RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000007827.4|UniProtKB=F7ETJ9 F7ETJ9 RNF17 PTHR16442:SF1 RING FINGER PROTEIN 17 RING FINGER PROTEIN 17 MONDO|Ensembl=ENSMODG00000002517.3|UniProtKB=A0A5F8HAY9 A0A5F8HAY9 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023 cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000038243.1|UniProtKB=A0A5F8HDP7 A0A5F8HDP7 NXPH4 PTHR17103:SF10 NEUREXOPHILIN NEUREXOPHILIN-4 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 GABA-ergic synapse#GO:0098982;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000003261.4|UniProtKB=F6T049 F6T049 ANP32B PTHR11375:SF2 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER B protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000021545.4|UniProtKB=A0A5F8GSY4 A0A5F8GSY4 FOSB PTHR23351:SF3 FOS TRANSCRIPTION FACTOR-RELATED PROTEIN FOSB sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic leucine zipper transcription factor#PC00056 Gonadotropin-releasing hormone receptor pathway#P06664>Fosb#G06666;Gonadotropin-releasing hormone receptor pathway#P06664>Fosb#G06878;Gonadotropin-releasing hormone receptor pathway#P06664>FOS#P06709 MONDO|Ensembl=ENSMODG00000024970.2|UniProtKB=A0A5F8GCL7 A0A5F8GCL7 PTHR28492:SF1 HYPOTHETICAL PROTEIN LOC691921 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 6 cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000018345.4|UniProtKB=A0A5F8G264 A0A5F8G264 SYNCRIP PTHR21245:SF11 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Q RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000006037.4|UniProtKB=F6ZUC5 F6ZUC5 MLH3 PTHR10073:SF47 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL DNA MISMATCH REPAIR PROTEIN MLH3 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565 cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000041583.1|UniProtKB=A0A5F8HD13 A0A5F8HD13 LOC100020048 PTHR48002:SF21 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011718.4|UniProtKB=F7FT54 F7FT54 FGF8 PTHR11486:SF3 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 8 binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;fibroblast growth factor receptor binding#GO:0005104 positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;nervous system development#GO:0007399;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;positive regulation of signal transduction#GO:0009967;dorsal/ventral pattern formation#GO:0009953;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;pattern specification process#GO:0007389;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;response to fibroblast growth factor#GO:0071774;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008 extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000009942.4|UniProtKB=F6R7Y2 F6R7Y2 RSU1 PTHR45752:SF156 LEUCINE-RICH REPEAT-CONTAINING RAS SUPPRESSOR PROTEIN 1 Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018698.4|UniProtKB=F7FQJ8 F7FQJ8 CYP27C1 PTHR24291:SF9 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 27C1 organic acid binding#GO:0043177;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;lipid binding#GO:0008289;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;alcohol binding#GO:0043178;oxidoreductase activity#GO:0016491 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>1alpha-Hydroxylase#P04603 MONDO|Ensembl=ENSMODG00000006108.3|UniProtKB=F7F0M1 F7F0M1 LOC100024114 PTHR13703:SF68 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;intracellular signaling cassette#GO:0141124;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000025463.3|UniProtKB=F6RJM4 F6RJM4 PTHR23268:SF47 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 11-1 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000001644.4|UniProtKB=F6T7Q6 F6T7Q6 CARTPT PTHR16655:SF0 COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PROTEIN COCAINE- AND AMPHETAMINE-REGULATED TRANSCRIPT PROTEIN regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of bone remodeling#GO:0046850;response to nutrient levels#GO:0031667;regulation of tissue remodeling#GO:0034103;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of bone resorption#GO:0045124;cellular response to stress#GO:0033554;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;response to starvation#GO:0042594;negative regulation of biological process#GO:0048519 cell body#GO:0044297;extracellular region#GO:0005576;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000020381.4|UniProtKB=F7F684 F7F684 BEST3 PTHR10736:SF2 BESTROPHIN BESTROPHIN-3 monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000004477.4|UniProtKB=F6VRI7 F6VRI7 ANKRD42 PTHR24201:SF2 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 42 RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;transcription factor binding#GO:0008134;binding#GO:0005488 kinase inhibitor#PC00139;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000002978.4|UniProtKB=F6Q542 F6Q542 EXOSC3 PTHR21321:SF1 PNAS-3 RELATED EXOSOME COMPLEX COMPONENT RRP40 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 snRNA metabolic process#GO:0016073;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;snRNA processing#GO:0016180;regulation of gene expression#GO:0010468;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;ribosome biogenesis#GO:0042254;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;maturation of 5.8S rRNA#GO:0000460;negative regulation of metabolic process#GO:0009892;ribonucleoprotein complex biogenesis#GO:0022613;snRNA 3'-end processing#GO:0034472;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000003493.2|UniProtKB=F7CS35 F7CS35 VPS9D1 PTHR23101:SF98 RAB GDP/GTP EXCHANGE FACTOR VPS9 DOMAIN-CONTAINING PROTEIN 1 guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular vesicle#GO:0097708;cytosol#GO:0005829;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000016833.4|UniProtKB=F6R272 F6R272 CAMK1D PTHR24347:SF252 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1D calmodulin binding#GO:0005516;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of chemotaxis#GO:0050920;signaling#GO:0023052;regulation of leukocyte migration#GO:0002685;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of granulocyte chemotaxis#GO:0071622;cell communication#GO:0007154;regulation of cell motility#GO:2000145;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of response to external stimulus#GO:0032101;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000027686.2|UniProtKB=K7E4X8 K7E4X8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000039050.1|UniProtKB=F7AN38 F7AN38 PTHR26450:SF42 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017529.4|UniProtKB=F6RTB1 F6RTB1 VNN1 PTHR10609:SF16 BIOTINIDASE-RELATED PANTETHEINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 hydrolase#PC00121 MONDO|Gene=DNTT|UniProtKB=O02789 O02789 DNTT PTHR11276:SF21 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA NUCLEOTIDYLEXOTRANSFERASE catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA-directed DNA polymerase activity#GO:0003887 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;double-strand break repair#GO:0006302;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009;DNA-directed DNA polymerase#PC00018 MONDO|Ensembl=ENSMODG00000028066.2|UniProtKB=K7E3P2 K7E3P2 PTHR46890:SF56 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED OS06G0484800 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000020712.4|UniProtKB=A0A5F8G1X2 A0A5F8G1X2 ADH7 PTHR43880:SF2 ALCOHOL DEHYDROGENASE ALL-TRANS-RETINOL DEHYDROGENASE [NAD(+)] ADH7 zinc ion binding#GO:0008270;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;ion binding#GO:0043167;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;metal ion binding#GO:0046872;cation binding#GO:0043169;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;response to chemical#GO:0042221;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;regulation of biological quality#GO:0065008;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;small molecule catabolic process#GO:0044282;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;regulation of hormone levels#GO:0010817;monocarboxylic acid metabolic process#GO:0032787;cellular detoxification of aldehyde#GO:0110095;carboxylic acid metabolic process#GO:0019752;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;biological regulation#GO:0065007;aldehyde catabolic process#GO:0046185;hormone metabolic process#GO:0042445;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;retinol metabolic process#GO:0042572;catabolic process#GO:0009056;response to toxic substance#GO:0009636;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000008981.3|UniProtKB=F7FRK7 F7FRK7 LOC100010757 PTHR26453:SF78 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T27-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015484.5|UniProtKB=F6S361 F6S361 GTF3C1 PTHR15180:SF1 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;rRNA transcription#GO:0009303;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 transcription factor TFIIIC complex#GO:0000127;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000051329.1|UniProtKB=A0A5F8HGS4 A0A5F8HGS4 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000042589.1|UniProtKB=A0A5F8GBN2 A0A5F8GBN2 PTHR12232:SF4 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000041802.1|UniProtKB=A0A5F8GE28 A0A5F8GE28 GOSR1 PTHR21094:SF2 GOS-28 SNARE- RELATED GOLGI SNAP RECEPTOR COMPLEX MEMBER 1 SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle fusion#GO:0006906;intra-Golgi vesicle-mediated transport#GO:0006891;cellular component organization#GO:0016043;localization#GO:0051179 cytoplasm#GO:0005737;Golgi cisterna#GO:0031985;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;Golgi stack#GO:0005795;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 SNARE protein#PC00034;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000037691.1|UniProtKB=A0A5F8GD72 A0A5F8GD72 PCBP4 PTHR10288:SF166 KH DOMAIN CONTAINING RNA BINDING PROTEIN POLY(RC)-BINDING PROTEIN 4 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000004412.3|UniProtKB=F6SV42 F6SV42 GPC2 PTHR10822:SF24 GLYPICAN GLYPICAN-2 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;signaling#GO:0023052;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224;regulation of protein localization#GO:0032880;regulation of protein localization to membrane#GO:1905475;signal transduction#GO:0007165;cellular process#GO:0009987;cell migration#GO:0016477;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;regulation of localization#GO:0032879 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;cell surface#GO:0009986;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000027653.2|UniProtKB=K7E2F6 K7E2F6 LOC103097074 PTHR10837:SF3 PEPTIDYLARGININE DEIMINASE PROTEIN-ARGININE DEIMINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000008444.3|UniProtKB=F7AKA1 F7AKA1 monDomV1R1235 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016654.4|UniProtKB=A0A5F8G8V4 A0A5F8G8V4 PFKFB3 PTHR10606:SF41 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE 3 hydrolase activity#GO:0016787;phosphotransferase activity, alcohol group as acceptor#GO:0016773;sugar-phosphatase activity#GO:0050308;phosphoric ester hydrolase activity#GO:0042578;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;kinase activity#GO:0016301 phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181;carbohydrate phosphatase#PC00066;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000015495.4|UniProtKB=F6WFC7 F6WFC7 TSPAN12 PTHR19282:SF462 TETRASPANIN TETRASPANIN-12 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000027813.2|UniProtKB=K7E597 K7E597 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000038852.1|UniProtKB=A0A5F8GNG8 A0A5F8GNG8 ASB18 PTHR24134:SF24 ANKYRIN REPEAT-CONTAINING PROTEIN DDB_G0279043 ANKYRIN REPEAT AND SOCS BOX CONTAINING 18 MONDO|Ensembl=ENSMODG00000000040.3|UniProtKB=A0A5F8G1X4 A0A5F8G1X4 PCDH18 PTHR24028:SF9 CADHERIN-87A PROTOCADHERIN-18 cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000044577.1|UniProtKB=K7E1R7 K7E1R7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000043371.1|UniProtKB=A0A5F8GU41 A0A5F8GU41 PTHR12570:SF13 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED MAGNESIUM TRANSPORTER NIPA3 transport#GO:0006810;magnesium ion transport#GO:0015693;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000012423.4|UniProtKB=A0A5F8G616 A0A5F8G616 PKN2 PTHR24356:SF322 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE N2 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;PDGF signaling pathway#P00047>PKC#P01150;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074 MONDO|Ensembl=ENSMODG00000000374.4|UniProtKB=F7EWV1 F7EWV1 RBL1 PTHR13742:SF20 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RETINOBLASTOMA-LIKE PROTEIN 1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;negative regulation of cell cycle process#GO:0010948;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;negative regulation of mitotic cell cycle phase transition#GO:1901991 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 p53 pathway feedback loops 2#P04398>Rb#P04654 MONDO|Ensembl=ENSMODG00000003165.4|UniProtKB=F6WDF5 F6WDF5 EML5 PTHR13720:SF16 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 5 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000040209.1|UniProtKB=A0A5F8GYB5 A0A5F8GYB5 ASCC1 PTHR13360:SF1 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000001990.4|UniProtKB=F6RI81 F6RI81 CARNMT1 PTHR12303:SF14 CARNOSINE N-METHYLTRANSFERASE PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE CARNMT1 transferase activity#GO:0016740;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000012599.4|UniProtKB=A0A5F8GHQ1 A0A5F8GHQ1 PTHR10697:SF1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323 MONDO|Ensembl=ENSMODG00000009351.4|UniProtKB=F7G0C0 F7G0C0 PTHR13771:SF3 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 2 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155;cell adhesion mediated by integrin#GO:0033627;leukocyte cell-cell adhesion#GO:0007159 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000018956.4|UniProtKB=A0A5F8HED9 A0A5F8HED9 MAD2L1BP PTHR15681:SF1 MAD2L1-BINDING PROTEIN MAD2L1-BINDING PROTEIN intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000008155.3|UniProtKB=F7ELD7 F7ELD7 H1-10 PTHR11467:SF21 HISTONE H1 HISTONE H1.10 chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;nucleosome binding#GO:0031491;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877;DNA binding#GO:0003677 negative regulation of cellular process#GO:0048523;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of DNA recombination#GO:0000018;chromosome condensation#GO:0030261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;negative regulation of biological process#GO:0048519;negative regulation of DNA recombination#GO:0045910;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000005987.4|UniProtKB=F6SLC4 F6SLC4 LOC100021613 PTHR10885:SF24 ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity#GO:0003824 metabolic process#GO:0008152;isoprenoid biosynthetic process#GO:0008299;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407;isoprenoid metabolic process#GO:0006720;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microbody#GO:0042579;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 isomerase#PC00135 MONDO|Ensembl=ENSMODG00000009808.4|UniProtKB=F7BED1 F7BED1 PTHR25462:SF302 BONUS, ISOFORM C-RELATED PROTEIN PML ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;SUMO transferase activity#GO:0019789;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;immune system process#GO:0002376;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;defense response to virus#GO:0051607;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;response to external stimulus#GO:0009605;defense response#GO:0006952;apoptotic signaling pathway#GO:0097190;innate immune response#GO:0045087;DNA damage response#GO:0006974;biological regulation#GO:0065007;response to other organism#GO:0051707;immune response#GO:0006955 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604 ubiquitin-protein ligase#PC00234 p53 pathway#P00059>PML#P04618;p53 pathway#P00059>PML#G04701 MONDO|Ensembl=ENSMODG00000002815.4|UniProtKB=A0A5F8H8G6 A0A5F8H8G6 PTHR43184:SF9 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A2 phosphate transmembrane transporter activity#GO:0005315;carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;inorganic anion transport#GO:0015698;transport#GO:0006810;organophosphate ester transport#GO:0015748;phosphate ion transport#GO:0006817;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 transporter#PC00227 MONDO|Ensembl=ENSMODG00000048471.1|UniProtKB=A0A5F8GW35 A0A5F8GW35 MRRF PTHR20982:SF10 RIBOSOME RECYCLING FACTOR RIBOSOME-RECYCLING FACTOR, MITOCHONDRIAL binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;ribosomal large subunit binding#GO:0043023;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;mitochondrial gene expression#GO:0140053;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;organelle disassembly#GO:1903008;translation#GO:0006412;translational termination#GO:0006415;protein-containing complex disassembly#GO:0032984;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 translation release factor#PC00225 MONDO|Ensembl=ENSMODG00000022682.3|UniProtKB=K7E3A6 K7E3A6 CA11 PTHR18952:SF93 CARBONIC ANHYDRASE CARBONIC ANHYDRASE-RELATED PROTEIN 11 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000007024.4|UniProtKB=A0A5F8H4Q6 A0A5F8H4Q6 CYP2D6 PTHR24300:SF1 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2D6-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;tetrapyrrole binding#GO:0046906;binding#GO:0005488 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;icosanoid metabolic process#GO:0006690;response to chemical#GO:0042221;cellular response to xenobiotic stimulus#GO:0071466;olefinic compound metabolic process#GO:0120254;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;oxoacid metabolic process#GO:0043436;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;xenobiotic metabolic process#GO:0006805 intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000018973.5|UniProtKB=F7FPK3 F7FPK3 ABCC10 PTHR24223:SF330 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 10 ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;xenobiotic transmembrane transporter activity#GO:0042910 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000000625.4|UniProtKB=A0A5F8HK00 A0A5F8HK00 PTHR23055:SF30 CALCIUM BINDING PROTEINS KV CHANNEL-INTERACTING PROTEIN 4 molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;cation binding#GO:0043169;channel regulator activity#GO:0016247;metal ion binding#GO:0046872;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765 membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000049225.1|UniProtKB=A0A5F8G8Y7 A0A5F8G8Y7 SNAPIN PTHR31305:SF3 SNARE-ASSOCIATED PROTEIN SNAPIN SNARE-ASSOCIATED PROTEIN SNAPIN protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 synaptic signaling#GO:0099536;monoatomic ion homeostasis#GO:0050801;synaptic vesicle transport#GO:0048489;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;regulated exocytosis#GO:0045055;chemical homeostasis#GO:0048878;vesicle-mediated transport in synapse#GO:0099003;endosomal transport#GO:0016197;exocytosis#GO:0006887;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;export from cell#GO:0140352;signaling#GO:0023052;lysosomal transport#GO:0007041;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;secretion by cell#GO:0032940;vesicle localization#GO:0051648;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;intracellular transport#GO:0046907;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;anterograde trans-synaptic signaling#GO:0098916;homeostatic process#GO:0042592;organelle localization#GO:0051640;regulation of pH#GO:0006885;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;regulation of intracellular pH#GO:0051453;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154 secretory vesicle#GO:0099503;presynapse#GO:0098793;transport vesicle#GO:0030133;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cell junction#GO:0030054;intracellular protein-containing complex#GO:0140535;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle#GO:0008021;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;BLOC-1 complex#GO:0031083;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000009822.5|UniProtKB=F6RXA9 F6RXA9 LOXL1 PTHR45817:SF8 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 1 catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 oxidase#PC00175;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000020830.4|UniProtKB=F6RLA3 F6RLA3 PTHR10624:SF9 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR-RELATED LY6_PLAUR DOMAIN-CONTAINING PROTEIN 5 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008076.3|UniProtKB=F6YJP8 F6YJP8 CCS PTHR10003:SF86 SUPEROXIDE DISMUTASE CU-ZN -RELATED COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;molecular carrier activity#GO:0140104;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;oxidoreductase activity#GO:0016491;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;copper ion binding#GO:0005507 response to stress#GO:0006950;cellular process#GO:0009987;cellular oxidant detoxification#GO:0098869;cellular response to oxygen-containing compound#GO:1901701;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;superoxide metabolic process#GO:0006801;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;response to reactive oxygen species#GO:0000302;cellular response to stimulus#GO:0051716;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;cellular response to chemical stimulus#GO:0070887;cellular detoxification#GO:1990748;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000014536.3|UniProtKB=F7E9G8 F7E9G8 METTL6 PTHR22809:SF5 METHYLTRANSFERASE-RELATED TRNA N(3)-CYTIDINE METHYLTRANSFERASE METTL6 methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000027359.2|UniProtKB=A0ACM8QDD3 A0ACM8QDD3 CD4 PTHR11422:SF0 T-CELL SURFACE GLYCOPROTEIN CD4 T-CELL SURFACE GLYCOPROTEIN CD4 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000046217.1|UniProtKB=A0A5F8GKX1 A0A5F8GKX1 LOC100021834 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014373.3|UniProtKB=A0A5F8HKB1 A0A5F8HKB1 LRGUK PTHR23117:SF18 GUANYLATE KINASE-RELATED LEUCINE-RICH REPEAT AND GUANYLATE KINASE DOMAIN-CONTAINING PROTEIN phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 male gamete generation#GO:0048232;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;plasma membrane bounded cell projection organization#GO:0120036;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;spermatogenesis#GO:0007283;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleoside phosphate metabolic process#GO:0006753;reproductive process#GO:0022414;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;microtubule cytoskeleton organization#GO:0000226;organophosphate biosynthetic process#GO:0090407;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;nucleoside diphosphate metabolic process#GO:0009132;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;ribose phosphate biosynthetic process#GO:0046390;cell projection assembly#GO:0030031;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;microtubule-based process#GO:0007017;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;cell projection organization#GO:0030030;small molecule metabolic process#GO:0044281;gamete generation#GO:0007276;cellular component organization#GO:0016043;phosphorus metabolic process#GO:0006793;cilium assembly#GO:0060271;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;cilium organization#GO:0044782;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135 intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 transferase#PC00220;kinase#PC00137 MONDO|Ensembl=ENSMODG00000017367.3|UniProtKB=F6VIH2 F6VIH2 RINT1 PTHR13520:SF0 RAD50-INTERACTING PROTEIN 1 RINT-1 RAD50-INTERACTING PROTEIN 1 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;vesicle tethering complex#GO:0099023;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000021257.4|UniProtKB=A0A5F8GGL2 A0A5F8GGL2 GYG1 PTHR11183:SF164 GLYCOGENIN SUBFAMILY MEMBER GLYCOGENIN-1 UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;glycogen biosynthetic process#GO:0005978;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;glucan biosynthetic process#GO:0009250;polysaccharide biosynthetic process#GO:0000271;energy reserve metabolic process#GO:0006112 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000012010.5|UniProtKB=F7D2K5 F7D2K5 PPP1R9B PTHR16154:SF24 NEURABIN NEURABIN-2 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;intracellular signaling cassette#GO:0141124;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;actin filament-based process#GO:0030029;system development#GO:0048731;supramolecular fiber organization#GO:0097435;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;anatomical structure development#GO:0048856;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;actin filament organization#GO:0007015;neurogenesis#GO:0022008;calcium-mediated signaling#GO:0019722;cellular developmental process#GO:0048869 postsynapse#GO:0098794;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;cell cortex#GO:0005938;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;dendrite#GO:0030425;filopodium#GO:0030175;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;neuron projection#GO:0043005;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000028931.2|UniProtKB=A0A5F8GTP1 A0A5F8GTP1 PTHR47609:SF1 MICOS COMPLEX SUBUNIT MIC25 MICOS COMPLEX SUBUNIT MIC25 mitochondrial membrane organization#GO:0007006;inner mitochondrial membrane organization#GO:0007007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cellular component organization or biogenesis#GO:0071840 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000008819.4|UniProtKB=A0A5F8G846 A0A5F8G846 SDCBP PTHR12345:SF10 SYNTENIN RELATED SYNTENIN-1 carbohydrate derivative binding#GO:0097367;binding#GO:0005488;protein binding#GO:0005515 regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of response to stimulus#GO:0048583 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000023430.3|UniProtKB=F6X116 F6X116 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000022970.2|UniProtKB=F6UXU3 F6UXU3 PTHR11937:SF54 ACTIN ACTIN-LIKE 11 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000010990.2|UniProtKB=F7APE8 F7APE8 PTHR16521:SF3 TYPE-1 ANGIOTENSIN II RECEPTOR-ASSOCIATED PROTEIN TYPE-1 ANGIOTENSIN II RECEPTOR-ASSOCIATED PROTEIN regulation of blood pressure#GO:0008217;circulatory system process#GO:0003013;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;system process#GO:0003008;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000012640.4|UniProtKB=F6WEB0 F6WEB0 ERP44 PTHR46295:SF1 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000024797.2|UniProtKB=F7FPG2 F7FPG2 APOLD1 PTHR14096:SF1 APOLIPOPROTEIN L APOLIPOPROTEIN L DOMAIN-CONTAINING PROTEIN 1 lipid binding#GO:0008289;binding#GO:0005488 developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;regulation of epithelial cell differentiation#GO:0030856;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;tube development#GO:0035295;animal gross anatomical part developmental process#GO:0160108;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;system development#GO:0048731;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;regulation of multicellular organismal development#GO:2000026;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793 membrane#GO:0016020;cellular anatomical structure#GO:0110165 apolipoprotein#PC00052;transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000008761.3|UniProtKB=F6RGW0 F6RGW0 MINDY2 PTHR18063:SF8 NF-E2 INDUCIBLE PROTEIN UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-2 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;deubiquitinase activity#GO:0101005 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000017525.4|UniProtKB=F7EI80 F7EI80 PTHR10609:SF4 BIOTINIDASE-RELATED VASCULAR NON-INFLAMMATORY MOLECULE 3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;metabolic process#GO:0008152;cellular process#GO:0009987 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000007541.3|UniProtKB=F7GAX1 F7GAX1 EIF2S3 PTHR42854:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;translation factor activity#GO:0180051;RNA binding#GO:0003723;tRNA binding#GO:0000049;translation initiation factor activity#GO:0003743 cytoplasmic translational initiation#GO:0002183;translation#GO:0006412;translational initiation#GO:0006413;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000029615.2|UniProtKB=K7DZ51 K7DZ51 PTHR14947:SF28 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000039816.1|UniProtKB=F6VFI4 F6VFI4 PTHR26454:SF0 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018216.4|UniProtKB=F6PGQ1 F6PGQ1 GSK3B PTHR24057:SF8 GLYCOGEN SYNTHASE KINASE-3 ALPHA GLYCOGEN SYNTHASE KINASE-3 BETA catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;beta-catenin binding#GO:0008013;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674 positive regulation of apoptotic process#GO:0043065;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;response to chemical#GO:0042221;regulation of microtubule cytoskeleton organization#GO:0070507;response to hormone#GO:0009725;regulation of protein metabolic process#GO:0051246;regulation of neuron apoptotic process#GO:0043523;positive regulation of autophagy#GO:0010508;regulation of TOR signaling#GO:0032006;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;regulation of intracellular signal transduction#GO:1902531;negative regulation of canonical Wnt signaling pathway#GO:0090090;positive regulation of protein metabolic process#GO:0051247;response to oxygen-containing compound#GO:1901700;positive regulation of programmed cell death#GO:0043068;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of programmed cell death#GO:0043067;positive regulation of proteasomal protein catabolic process#GO:1901800;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of Wnt signaling pathway#GO:0030178;cellular response to nitrogen compound#GO:1901699;regulation of signal transduction#GO:0009966;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of protein catabolic process#GO:0042176;response to nitrogen compound#GO:1901698;positive regulation of protein catabolic process#GO:0045732;regulation of cytoskeleton organization#GO:0051493;negative regulation of TOR signaling#GO:0032007;cellular response to peptide hormone stimulus#GO:0071375;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;negative regulation of signal transduction#GO:0009968;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;insulin receptor signaling pathway#GO:0008286;cellular response to hormone stimulus#GO:0032870;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of Wnt signaling pathway#GO:0030111;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;positive regulation of catabolic process#GO:0009896;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;positive regulation of neuron apoptotic process#GO:0043525;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of microtubule-based process#GO:0032886;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;axon#GO:0030424;catalytic complex#GO:1902494;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;glutamatergic synapse#GO:0098978;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;cytosol#GO:0005829;neuron projection#GO:0043005;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 Cadherin signaling pathway#P00012>GSK3beta#P00477;Hedgehog signaling pathway#P00025>GSK3#P00692;Interleukin signaling pathway#P00036>GSK3#P00976;Ras Pathway#P04393>GSK3#P04546;CCKR signaling map#P06959>GSK3beta#P07199;Gonadotropin-releasing hormone receptor pathway#P06664>GSK3#P06827;Angiogenesis#P00005>GSK3beta#P00211;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GSK#P00714;Wnt signaling pathway#P00057>Glycogen Synthase Kinase-3Beta#P01441;Alzheimer disease-presenilin pathway#P00004>GSK-3beta#P00175;PI3 kinase pathway#P00048>GSK3#P01181;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902;PDGF signaling pathway#P00047>GSK3#P01153 MONDO|Ensembl=ENSMODG00000050430.1|UniProtKB=A0A5F8G295 A0A5F8G295 PTHR24100:SF64 BUTYROPHILIN BUTYROPHILIN, SUBFAMILY 3, MEMBER A3-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000013655.4|UniProtKB=A0A5F8GLV3 A0A5F8GLV3 DSCAML1 PTHR10075:SF72 BASIGIN RELATED CELL ADHESION MOLECULE DSCAML1 nervous system development#GO:0007399;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 cell adhesion molecule#PC00069 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919 MONDO|Ensembl=ENSMODG00000014603.4|UniProtKB=A0A5F8GSQ1 A0A5F8GSQ1 TMEM209 PTHR21780:SF0 TRANSMEMBRANE PROTEIN 209 TRANSMEMBRANE PROTEIN 209 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000046294.1|UniProtKB=A0A5F8H9D4 A0A5F8H9D4 PTHR23304:SF189 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000007816.4|UniProtKB=F7B234 F7B234 DNAJB5 PTHR24078:SF586 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 5 protein binding#GO:0005515;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000020466.4|UniProtKB=F7FJ89 F7FJ89 NAV3 PTHR12784:SF18 STEERIN NEURON NAVIGATOR 3 system development#GO:0048731;nervous system development#GO:0007399;multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;microtubule end#GO:1990752;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000003562.4|UniProtKB=F7G152 F7G152 NTMT2 PTHR12753:SF2 AD-003 - RELATED N-TERMINAL XAA-PRO-LYS N-METHYLTRANSFERASE 2 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000043193.1|UniProtKB=A0A5F8HDS3 A0A5F8HDS3 CHST10 PTHR12137:SF2 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 10 transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 transferase#PC00220 MONDO|Ensembl=ENSMODG00000048977.1|UniProtKB=A0A5F8H5E2 A0A5F8H5E2 LOC100016791 PTHR48018:SF168 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004231.4|UniProtKB=F6UBQ3 F6UBQ3 NHP2 PTHR23105:SF54 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 2 RNA binding#GO:0003723;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;binding#GO:0005488 rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;snRNA metabolic process#GO:0016073;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000012176.3|UniProtKB=F7CY62 F7CY62 PTHR10286:SF47 INORGANIC PYROPHOSPHATASE INORGANIC PYROPHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 pyrophosphatase#PC00196 MONDO|Ensembl=ENSMODG00000007331.4|UniProtKB=A0A5F8H237 A0A5F8H237 LOC100033206 PTHR24377:SF885 IP01015P-RELATED ZINC FINGER PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000023986.2|UniProtKB=F7E8H0 F7E8H0 LOC100617862 PTHR26450:SF195 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016489.4|UniProtKB=A0A5F8H7C1 A0A5F8H7C1 PTHR21290:SF28 SPHINGOMYELIN SYNTHETASE PHOSPHATIDYLCHOLINE:CERAMIDE CHOLINEPHOSPHOTRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingomyelin metabolic process#GO:0006684;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;ceramide metabolic process#GO:0006672 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000021287.4|UniProtKB=F7GE18 F7GE18 LAMP3 PTHR11506:SF30 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 3 localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;late endosome membrane#GO:0031902;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;membrane#GO:0016020;vesicle membrane#GO:0012506 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000045914.1|UniProtKB=A0A5F8G4M3 A0A5F8G4M3 PTHR36687:SF1 GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2-RELATED GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2 MONDO|Ensembl=ENSMODG00000014166.3|UniProtKB=F6TVG6 F6TVG6 PTHR10032:SF220 ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS TRANSCRIPTION FACTOR OVO-LIKE PROTEIN 3-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;developmental process#GO:0032502;epidermis development#GO:0008544;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000013268.3|UniProtKB=F7D9J4 F7D9J4 MINAR2 PTHR31530:SF4 MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1 MINAR1 FAMILY MEMBER MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1-LIKE transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014207.4|UniProtKB=F6TQC1 F6TQC1 SMARCC1 PTHR12802:SF9 SWI/SNF COMPLEX-RELATED SWI_SNF COMPLEX SUBUNIT SMARCC1 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000016558.4|UniProtKB=A0A5F8H2H0 A0A5F8H2H0 STX16 PTHR19957:SF83 SYNTAXIN SYNTAXIN-16 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;membrane fusion#GO:0061025;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 membrane#GO:0016020;membrane protein complex#GO:0098796;SNARE complex#GO:0031201;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 MONDO|Ensembl=ENSMODG00000029685.2|UniProtKB=K7E3M5 K7E3M5 LOC100021710 PTHR11430:SF142 LIPOCALIN LIPOCALIN_CYTOSOLIC FATTY-ACID BINDING DOMAIN-CONTAINING PROTEIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000014899.4|UniProtKB=A0A5F8GJM1 A0A5F8GJM1 CIB3 PTHR45791:SF7 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 3 metal ion binding#GO:0046872;cation binding#GO:0043169;magnesium ion binding#GO:0000287;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878 MONDO|Ensembl=ENSMODG00000011390.4|UniProtKB=F6SNQ4 F6SNQ4 LZTFL1 PTHR21635:SF0 LEUCINE ZIPPER TRANSCRIPTION FACTOR LIKE LEUCINE ZIPPER TRANSCRIPTION FACTOR-LIKE PROTEIN 1 sperm motility#GO:0097722;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;regulation of protein localization#GO:0032880;cilium-dependent cell motility#GO:0060285;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;biological regulation#GO:0065007;flagellated sperm motility#GO:0030317;microtubule-based process#GO:0007017;regulation of localization#GO:0032879 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000020967.4|UniProtKB=F6SND1 F6SND1 PCP4 PTHR15359:SF7 IG-LIKE DOMAIN-CONTAINING PROTEIN CALMODULIN REGULATOR PROTEIN PCP4 cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calmodulin binding#GO:0005516 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834 MONDO|Ensembl=ENSMODG00000011756.4|UniProtKB=F7CWG5 F7CWG5 ACP3 PTHR11567:SF221 ACID PHOSPHATASE-RELATED PROSTATIC ACID PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;acid phosphatase activity#GO:0003993;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;regulation of system process#GO:0044057;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000009179.4|UniProtKB=A0A5F8GN15 A0A5F8GN15 SYNE2 PTHR21524:SF5 SPECTRIN REPEAT CONTAINING NUCLEAR ENVELOPE PROTEIN 2 NESPRIN-2 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 transport#GO:0006810;organelle localization#GO:0051640;intracellular transport#GO:0046907;cellular localization#GO:0051641;nucleus organization#GO:0006997;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nuclear migration#GO:0007097;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967 MONDO|Ensembl=ENSMODG00000000651.4|UniProtKB=F6SUC7 F6SUC7 PTP4A3 PTHR23339:SF119 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE TYPE IVA 3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 cell migration#GO:0016477;endothelial cell migration#GO:0043542;cell motility#GO:0048870;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein phosphatase#PC00195;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000005807.4|UniProtKB=F6XEE3 F6XEE3 SMOC2 PTHR12352:SF21 SECRETED MODULAR CALCIUM-BINDING PROTEIN SPARC-RELATED MODULAR CALCIUM-BINDING PROTEIN 2 extracellular matrix binding#GO:0050840;binding#GO:0005488;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367;heparin binding#GO:0008201 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987 basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000005198.3|UniProtKB=A0A5F8G4P6 A0A5F8G4P6 CAPN5 PTHR10183:SF402 CALPAIN CALPAIN-5 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 MONDO|Ensembl=ENSMODG00000019002.3|UniProtKB=F7CP91 F7CP91 MEA1 PTHR17005:SF3 MALE-ENHANCED ANTIGEN-1 MALE-ENHANCED ANTIGEN 1 MONDO|Ensembl=ENSMODG00000041207.1|UniProtKB=F6Z4N8 F6Z4N8 PTHR48002:SF176 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000049452.1|UniProtKB=A0A5F8GJC6 A0A5F8GJC6 TTC33 PTHR15544:SF0 OSMOSIS RESPONSIVE FACTOR TETRATRICOPEPTIDE REPEAT PROTEIN 33 MONDO|Ensembl=ENSMODG00000024751.2|UniProtKB=F7GKI1 F7GKI1 PTHR11627:SF1 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE A aldehyde-lyase activity#GO:0016832;fructose-bisphosphate aldolase activity#GO:0004332;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 lyase#PC00144;aldolase#PC00044 Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959;Glycolysis#P00024>Aldolase#P00679 MONDO|Ensembl=ENSMODG00000040828.1|UniProtKB=A0A5F8GGV3 A0A5F8GGV3 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000046487.1|UniProtKB=A0A5F8G211 A0A5F8G211 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000046573.1|UniProtKB=A0A5F8H9Z1 A0A5F8H9Z1 C1QTNF7 PTHR15427:SF24 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 7 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000040018.1|UniProtKB=A0A5F8H313 A0A5F8H313 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000003570.4|UniProtKB=F7G0S5 F7G0S5 DCAF11 PTHR19847:SF7 DDB1- AND CUL4-ASSOCIATED FACTOR 11 DDB1- AND CUL4-ASSOCIATED FACTOR 11 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000010942.5|UniProtKB=H9H6G6 H9H6G6 PTHR12618:SF20 PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1 PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000004621.4|UniProtKB=F7B1H9 F7B1H9 GSE1 PTHR17608:SF4 GENETIC SUPPRESSOR ELEMENT 1 GENETIC SUPPRESSOR ELEMENT 1 MONDO|Ensembl=ENSMODG00000005081.4|UniProtKB=F7A4I2 F7A4I2 LMBR1 PTHR12625:SF1 LIPOCALIN-1 INTERACTING MEMBRANE RECEPTOR LIMR LIMB REGION 1 PROTEIN HOMOLOG transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004996.3|UniProtKB=A0A5F8HHI7 A0A5F8HHI7 NR1H4 PTHR24082:SF155 NUCLEAR HORMONE RECEPTOR BILE ACID RECEPTOR transcription regulator activity#GO:0140110;binding#GO:0005488;carboxylic acid binding#GO:0031406;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;organic acid binding#GO:0043177;transcription cis-regulatory region binding#GO:0000976;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;ion binding#GO:0043167;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;lipid homeostasis#GO:0055088;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of response to external stimulus#GO:0032102;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;chemical homeostasis#GO:0048878;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;homeostatic process#GO:0042592;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;negative regulation of defense response#GO:0031348;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;cholesterol homeostasis#GO:0042632;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000016643.4|UniProtKB=F7GGU1 F7GGU1 DERL2 PTHR11009:SF5 DER1-LIKE PROTEIN, DERLIN DERLIN-2 response to stimulus#GO:0050896;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to unfolded protein#GO:0006986;cell communication#GO:0007154;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to chemical#GO:0042221;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000007053.3|UniProtKB=F6VQN8 F6VQN8 PTHR11904:SF12 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;pyridine-containing compound metabolic process#GO:0072524;purine nucleoside metabolic process#GO:0042278;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;nucleobase-containing small molecule catabolic process#GO:0034656;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;nucleoside catabolic process#GO:0009164;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;purine-containing compound catabolic process#GO:0072523;purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172;kinase#PC00137 Xanthine and guanine salvage pathway#P02788>Guanosine phosphorylase#P03250;Adenine and hypoxanthine salvage pathway#P02723>Deoxyinosine phosphorylase#P02812;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphorylase#P02805;Purine metabolism#P02769>Nucleoside Phosphorylase#P03115;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine phosphorylase#P02808;Adenine and hypoxanthine salvage pathway#P02723>Inosine phosphorylase#P02813;Xanthine and guanine salvage pathway#P02788>Deoxyguanosine phosphorylase#P03248 MONDO|Ensembl=ENSMODG00000008861.4|UniProtKB=A0A5F8GVN0 A0A5F8GVN0 AP1B1 PTHR11134:SF31 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-1 COMPLEX SUBUNIT BETA-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987 intracellular vesicle#GO:0097708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular organelle#GO:0043229;coated membrane#GO:0048475;coated vesicle#GO:0030135;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;vesicle coat#GO:0030120;cytoplasm#GO:0005737;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle membrane#GO:0030665;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network transport vesicle#GO:0030140;AP-1 adaptor complex#GO:0030121;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000019313.4|UniProtKB=F6YAQ7 F6YAQ7 PHF12 PTHR46309:SF28 PHD FINGER PROTEIN 12 PHD FINGER PROTEIN 12 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;chromatin#GO:0000785;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Sin3-type complex#GO:0070822;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000013150.4|UniProtKB=F7ACG9 F7ACG9 PYGL PTHR11468:SF3 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE, LIVER FORM glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 cellular process#GO:0009987;glycogen catabolic process#GO:0005980;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;generation of precursor metabolites and energy#GO:0006091;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;glucan catabolic process#GO:0009251;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;catabolic process#GO:0009056;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;carbohydrate catabolic process#GO:0016052;energy reserve metabolic process#GO:0006112 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220;glycosyltransferase#PC00111 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase a#P00718;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b#P00717 MONDO|Ensembl=ENSMODG00000002749.3|UniProtKB=A0A5F8H1K9 A0A5F8H1K9 LOC100028075 PTHR19359:SF158 CYTOCHROME B5 CYTOCHROME B5 TYPE B tetrapyrrole binding#GO:0046906;binding#GO:0005488;heme binding#GO:0020037 organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000024316.2|UniProtKB=Q2AB85 Q2AB85 TAS2R60 PTHR11394:SF32 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 60 taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016902.4|UniProtKB=A0A5F8HET0 A0A5F8HET0 PRPF18 PTHR13007:SF19 PRE-MRNA SPLICING FACTOR-RELATED PRE-MRNA-SPLICING FACTOR 18 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933 spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000021294.5|UniProtKB=F7G3V5 F7G3V5 FXR1 PTHR10603:SF6 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN RNA-BINDING PROTEIN FXR1 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 positive regulation of neurogenesis#GO:0050769;regulation of cell communication#GO:0010646;mRNA transport#GO:0051028;regulation of developmental process#GO:0050793;modulation of chemical synaptic transmission#GO:0050804;establishment of RNA localization#GO:0051236;regulation of cellular process#GO:0050794;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;regulation of macromolecule metabolic process#GO:0060255;regulation of neurogenesis#GO:0050767;regulation of RNA metabolic process#GO:0051252;positive regulation of translation#GO:0045727;anatomical structure development#GO:0048856;nucleic acid transport#GO:0050657;regulation of nervous system development#GO:0051960;positive regulation of biosynthetic process#GO:0009891;localization#GO:0051179;regulation of RNA stability#GO:0043487;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nitrogen compound transport#GO:0071705;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;regulation of translation#GO:0006417;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;regulation of neuronal synaptic plasticity#GO:0048168;regulation of cell differentiation#GO:0045595;transport#GO:0006810;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;post-transcriptional regulation of gene expression#GO:0010608;regulation of synaptic plasticity#GO:0048167;regulation of mRNA stability#GO:0043488;positive regulation of nervous system development#GO:0051962;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;regulation of trans-synaptic signaling#GO:0099177;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;regulation of mRNA metabolic process#GO:1903311;animal organ development#GO:0048513;positive regulation of cell differentiation#GO:0045597 cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;neuron projection#GO:0043005;nucleus#GO:0005634;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228 translation factor#PC00223;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000018391.4|UniProtKB=A0A5F8G6S6 A0A5F8G6S6 DOP1A PTHR14042:SF22 DOPEY-RELATED PROTEIN DOP1A retrograde transport, endosome to Golgi#GO:0042147;retrograde transport, vesicle recycling within Golgi#GO:0000301;establishment of localization in cell#GO:0051649;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794 MONDO|Ensembl=ENSMODG00000014770.4|UniProtKB=F7GGR4 F7GGR4 HPCAL1 PTHR23055:SF79 CALCIUM BINDING PROTEINS HIPPOCALCIN-LIKE PROTEIN 1 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000025109.2|UniProtKB=Q2ABA9 Q2ABA9 TAS2R1 PTHR11394:SF149 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 1 transmembrane signaling receptor activity#GO:0004888;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527 system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017494.5|UniProtKB=H9H733 H9H733 ZNF628 PTHR24393:SF182 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 628 transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000044865.1|UniProtKB=A0A5F8G987 A0A5F8G987 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000048415.1|UniProtKB=A0A5F8H9V0 A0A5F8H9V0 SLC51B PTHR36129:SF1 ORGANIC SOLUTE TRANSPORTER SUBUNIT BETA-RELATED ORGANIC SOLUTE TRANSPORTER SUBUNIT BETA organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;bile acid and bile salt transport#GO:0015721;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869;macromolecule localization#GO:0033036 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000002959.4|UniProtKB=F6PJS4 F6PJS4 EDAR PTHR12120:SF9 TNFR-CYS DOMAIN-CONTAINING PROTEIN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER EDAR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000000772.4|UniProtKB=F6RAJ5 F6RAJ5 ARHGAP10 PTHR12552:SF5 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN 10 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;cellular process#GO:0009987;negative regulation of biological process#GO:0048519;organelle organization#GO:0006996;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GTPase-activating protein#PC00257 Integrin signalling pathway#P00034>GRAF#P00926;PDGF signaling pathway#P00047>Rho#P01174 MONDO|Ensembl=ENSMODG00000013878.3|UniProtKB=F6W8I8 F6W8I8 NXPE4 PTHR16165:SF27 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 4 MONDO|Ensembl=ENSMODG00000021319.4|UniProtKB=A0A5F8HDQ2 A0A5F8HDQ2 ECT2 PTHR16777:SF2 PROTEIN ECT2 PROTEIN ECT2 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 mitotic cell cycle process#GO:1903047;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinesis#GO:0000910;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402;cell cycle#GO:0007049 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;nucleus#GO:0005634 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000001099.4|UniProtKB=F7DPH4 F7DPH4 LMO7 PTHR46767:SF1 LIM DOMAIN ONLY PROTEIN 7 LIM DOMAIN ONLY PROTEIN 7 MONDO|Ensembl=ENSMODG00000013664.3|UniProtKB=F6TXW6 F6TXW6 TICAM2 PTHR47230:SF2 TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1 TIR DOMAIN-CONTAINING ADAPTER MOLECULE 2 signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;positive regulation of signaling#GO:0023056;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of multicellular organismal process#GO:0051240;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;toll-like receptor signaling pathway#GO:0002224;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stress#GO:0080134;pattern recognition receptor signaling pathway#GO:0002221;regulation of gene expression#GO:0010468;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;activation of innate immune response#GO:0002218;regulation of cytokine production#GO:0001817;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;cellular response to stimulus#GO:0051716;positive regulation of type I interferon production#GO:0032481;positive regulation of signal transduction#GO:0009967;innate immune response-activating signaling pathway#GO:0002758;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;positive regulation of cell communication#GO:0010647;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TRIF#P01344 MONDO|Ensembl=ENSMODG00000008823.3|UniProtKB=A0A5F8GHK4 A0A5F8GHK4 KIF13B PTHR24115:SF978 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF13B cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000012449.4|UniProtKB=F6PJ87 F6PJ87 POMT1 PTHR10050:SF51 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE 1 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000000354.4|UniProtKB=F6RUB2 F6RUB2 DNAI3 PTHR12442:SF5 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 3 binding#GO:0005488;protein binding#GO:0005515 organelle assembly#GO:0070925;cilium movement#GO:0003341;inner dynein arm assembly#GO:0036159;cilium or flagellum-dependent cell motility#GO:0001539;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cilium-dependent cell motility#GO:0060285;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cell motility#GO:0048870;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ciliary plasm#GO:0097014;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;inner dynein arm#GO:0036156;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;dynein complex#GO:0030286;axonemal dynein complex#GO:0005858;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000010870.4|UniProtKB=A0A5F8HJ72 A0A5F8HJ72 AKAP10 PTHR13155:SF1 A-KINASE ANCHOR PROTEINS A-KINASE ANCHOR PROTEIN 10, MITOCHONDRIAL protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular protein localization#GO:0008104;localization#GO:0051179;macromolecule localization#GO:0033036 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017626.2|UniProtKB=F6ZSH8 F6ZSH8 PTHR38496:SF1 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000051612.1|UniProtKB=A0A5F8GPA2 A0A5F8GPA2 LOC100028613 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000017603.4|UniProtKB=A0A5F8HK48 A0A5F8HK48 TBC1D30 PTHR22957:SF601 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 30 enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000009237.4|UniProtKB=F7EDR3 F7EDR3 NELL1 PTHR24042:SF2 NEL HOMOLOG PROTEIN KINASE C-BINDING PROTEIN NELL1 glycosaminoglycan binding#GO:0005539;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;carbohydrate derivative binding#GO:0097367;heparin binding#GO:0008201 positive regulation of multicellular organismal process#GO:0051240;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell differentiation#GO:0045595 extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000020290.4|UniProtKB=F7BFZ2 F7BFZ2 PLCXD3 PTHR13593:SF33 FAMILY NOT NAMED PI-PLC X DOMAIN-CONTAINING PROTEIN 3 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000047646.1|UniProtKB=A0A5F8HJ73 A0A5F8HJ73 PTHR33166:SF1 GAG_P30 DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000001534.3|UniProtKB=F7EMU1 F7EMU1 LOC100012145 PTHR26453:SF301 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016911.4|UniProtKB=F6X141 F6X141 FBXO30 PTHR15933:SF13 PROTEIN CBG16327 F-BOX ONLY PROTEIN 30 MONDO|Ensembl=ENSMODG00000002151.4|UniProtKB=A0A5F8HK79 A0A5F8HK79 LOC100026196 PTHR43391:SF1 RETINOL DEHYDROGENASE-RELATED RETINOL DEHYDROGENASE 8 ISOFORM X1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000048591.1|UniProtKB=A0A5F8GR68 A0A5F8GR68 PTHR10966:SF0 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 transcription factor binding#GO:0008134;binding#GO:0005488;protein binding#GO:0005515 protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 MONDO|Ensembl=ENSMODG00000036657.1|UniProtKB=A0A5F8HBA8 A0A5F8HBA8 PTHR23262:SF248 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-6 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000047146.1|UniProtKB=A0A5F8GC61 A0A5F8GC61 PTHR11785:SF303 AMINO ACID TRANSPORTER Y+L AMINO ACID TRANSPORTER 1 L-amino acid transmembrane transporter activity#GO:0015179;basic amino acid transmembrane transporter activity#GO:0015174;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000015871.4|UniProtKB=F7BR98 F7BR98 PPP1R3A PTHR12307:SF2 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3A enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902;polysaccharide binding#GO:0030247;protein phosphatase binding#GO:0019903;protein binding#GO:0005515;carbohydrate binding#GO:0030246 regulation of glycogen biosynthetic process#GO:0005979;regulation of carbohydrate metabolic process#GO:0006109;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of polysaccharide metabolic process#GO:0032881;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000049189.1|UniProtKB=A0A5F8H461 A0A5F8H461 LOC100031129 PTHR24249:SF79 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 9 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000014646.4|UniProtKB=F7EQC4 F7EQC4 FKTN PTHR15407:SF42 FUKUTIN-RELATED RIBITOL-5-PHOSPHATE TRANSFERASE FKTN metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 MONDO|Ensembl=ENSMODG00000045966.1|UniProtKB=F6RLC1 F6RLC1 PTHR24225:SF0 CHEMOTACTIC RECEPTOR N-FORMYL PEPTIDE RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;immune receptor activity#GO:0140375;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000028479.2|UniProtKB=K7E673 K7E673 NEK5 PTHR44899:SF1 CAMK FAMILY PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE NEK5 phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000005457.3|UniProtKB=F7CGP1 F7CGP1 LOC100030299 PTHR26454:SF2 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6E1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003507.4|UniProtKB=F7C8J7 F7C8J7 SLC8B1 PTHR12266:SF39 NA+/CA2+ K+ INDEPENDENT EXCHANGER MITOCHONDRIAL SODIUM_CALCIUM EXCHANGER PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075 intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000036991.1|UniProtKB=A0A5F8GU91 A0A5F8GU91 LOC100618057 PTHR43658:SF5 SHORT-CHAIN DEHYDROGENASE/REDUCTASE SI:DKEY-238O13.4 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 regulation of biological quality#GO:0065008;estrogen metabolic process#GO:0008210;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;biological regulation#GO:0065007;steroid metabolic process#GO:0008202;hormone metabolic process#GO:0042445;small molecule metabolic process#GO:0044281;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000006549.2|UniProtKB=F7BV64 F7BV64 CDC34 PTHR24067:SF135 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 R1 catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000008168.4|UniProtKB=F7EKY6 F7EKY6 ARMC1 PTHR46840:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 1 ARMADILLO REPEAT-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000021430.4|UniProtKB=F7CB75 F7CB75 CIDEA PTHR12306:SF8 CELL DEATH ACTIVATOR CIDE LIPID TRANSFERASE CIDEA lipid transfer activity#GO:0120013;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 organelle organization#GO:0006996;programmed cell death#GO:0012501;cellular component organization#GO:0016043;lipid storage#GO:0019915;apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987;organelle fusion#GO:0048284;lipid droplet organization#GO:0034389;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000013880.2|UniProtKB=F6W8H5 F6W8H5 FFAR2 PTHR45822:SF5 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to fatty acid#GO:0071398;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to fatty acid#GO:0070542;cell communication#GO:0007154;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000007392.4|UniProtKB=F6YZX4 F6YZX4 LOC100015611 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000046489.1|UniProtKB=A0A5F8H8C5 A0A5F8H8C5 LOC100026651 PTHR33589:SF4 OS11G0524900 PROTEIN ZYMOGEN GRANULE MEMBRANE PROTEIN 16 MONDO|Ensembl=ENSMODG00000011356.3|UniProtKB=F6Q075 F6Q075 FTSJ1 PTHR10920:SF12 RIBOSOMAL RNA METHYLTRANSFERASE TRNA (CYTIDINE(32)_GUANOSINE(34)-2'-O)-METHYLTRANSFERASE methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173 nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000011082.4|UniProtKB=A0A5F8GL62 A0A5F8GL62 DSC1 PTHR24025:SF8 DESMOGLEIN FAMILY MEMBER DESMOCOLLIN-1 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161 cadherin#PC00057 MONDO|Ensembl=ENSMODG00000010314.4|UniProtKB=A0A5F8GVR9 A0A5F8GVR9 LOC107650783 PTHR24100:SF108 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 8 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune system process#GO:0002376;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000010018.4|UniProtKB=A0A5F8H2Y6 A0A5F8H2Y6 GRIPAP1 PTHR18978:SF1 GRIP-1 ASSOCIATED PROTEIN 1 GRIP1-ASSOCIATED PROTEIN 1 regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;regulation of vesicle-mediated transport#GO:0060627;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of biological quality#GO:0065008;regulation of localization#GO:0032879;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of transport#GO:0051049 membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;postsynapse#GO:0098794;vesicle#GO:0031982;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;early endosome membrane#GO:0031901;synaptic membrane#GO:0097060;plasma membrane region#GO:0098590;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;glutamatergic synapse#GO:0098978;plasma membrane#GO:0005886;cytoplasm#GO:0005737;presynaptic membrane#GO:0042734;vesicle membrane#GO:0012506;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000012197.4|UniProtKB=F7CEA7 F7CEA7 CDC23 PTHR12558:SF10 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 23 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;cell division#GO:0051301;regulation of cell cycle phase transition#GO:1901987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of mitotic nuclear division#GO:0007088;positive regulation of mitotic cell cycle#GO:0045931;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of mitotic sister chromatid separation#GO:0010965;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of chromosome organization#GO:0033044;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of nuclear division#GO:0051783;regulation of mitotic metaphase/anaphase transition#GO:0030071;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of organelle organization#GO:0010638;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;positive regulation of cellular component organization#GO:0051130;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of cellular component organization#GO:0051128;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of organelle organization#GO:0033043;positive regulation of mitotic nuclear division#GO:0045840;regulation of chromosome segregation#GO:0051983;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;proteasomal protein catabolic process#GO:0010498;positive regulation of cell cycle#GO:0045787;regulation of chromosome separation#GO:1905818;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000018258.4|UniProtKB=F6Q7W9 F6Q7W9 CLEC1A PTHR46490:SF1 C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 1 MEMBER A transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000024399.2|UniProtKB=F6Z456 F6Z456 monDomV1R1268 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011071.4|UniProtKB=H9H6H4 H9H6H4 PTHR22599:SF21 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 2 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000005648.2|UniProtKB=F7BW56 F7BW56 PTHR26453:SF110 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2G6 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000217.4|UniProtKB=F6SZK3 F6SZK3 PIWIL4 PTHR22891:SF43 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PIWI-LIKE PROTEIN 4 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;nucleic acid binding#GO:0003676;binding#GO:0005488;nuclease activity#GO:0004518;RNA binding#GO:0003723 multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;piRNA processing#GO:0034587;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;developmental process involved in reproduction#GO:0003006;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulatory ncRNA-mediated gene silencing#GO:0031047;spermatogenesis#GO:0007283;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;male gamete generation#GO:0048232;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558 nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;P granule#GO:0043186;intracellular anatomical structure#GO:0005622 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000024308.1|UniProtKB=F7EHY8 F7EHY8 LOC100024051 PTHR48018:SF91 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8U1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000036969.1|UniProtKB=A0A5F8H4L9 A0A5F8H4L9 LOC100028006 PTHR26452:SF310 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027779.1|UniProtKB=K7E1R5 K7E1R5 LOC107651026 PTHR33166:SF1 GAG_P30 DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000018220.3|UniProtKB=F6PGM6 F6PGM6 GPRC5A PTHR14511:SF7 G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5 RETINOIC ACID-INDUCED PROTEIN 3 protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;extracellular region#GO:0005576;signaling receptor complex#GO:0043235;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000047351.1|UniProtKB=A0A5F8GND8 A0A5F8GND8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024369.2|UniProtKB=F6S8I4 F6S8I4 LOC100618443 PTHR48002:SF60 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048727.1|UniProtKB=A0A5F8H5U7 A0A5F8H5U7 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000042189.1|UniProtKB=A0A5F8H0A7 A0A5F8H0A7 PTHR22803:SF116 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED REGENERATING ISLET-DERIVED PROTEIN 3-GAMMA growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179 response to nitrogen compound#GO:1901698;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;regulation of cell population proliferation#GO:0042127;response to oxygen-containing compound#GO:1901700;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;defense response#GO:0006952;response to external stimulus#GO:0009605;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;defense response to other organism#GO:0098542;response to chemical#GO:0042221;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to hormone#GO:0009725;response to biotic stimulus#GO:0009607 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000014867.4|UniProtKB=F7BYC4 F7BYC4 GPSM3 PTHR47617:SF1 G-PROTEIN SIGNALING MODULATOR 3 G PROTEIN-SIGNALING MODULATOR 3 positive regulation of response to external stimulus#GO:0032103;positive regulation of inflammatory response#GO:0050729;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;regulation of defense response#GO:0031347;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789 MONDO|Ensembl=ENSMODG00000043108.1|UniProtKB=A0A5F8H1Z6 A0A5F8H1Z6 PTHR12356:SF18 NUCLEAR MOVEMENT PROTEIN NUDC NUDC DOMAIN-CONTAINING PROTEIN 2 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000001451.4|UniProtKB=F7BBU9 F7BBU9 IRX1 PTHR11211:SF13 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;cell development#GO:0048468;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000047109.1|UniProtKB=A0A5F8HEK5 A0A5F8HEK5 LOC103096673 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000004724.4|UniProtKB=A0A5F8HIC2 A0A5F8HIC2 PIN1 PTHR10657:SF4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;cis-trans isomerase activity#GO:0016859;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000047382.1|UniProtKB=A0A5F8H0G2 A0A5F8H0G2 PTHR19367:SF18 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 18 immune response#GO:0006955;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000027814.2|UniProtKB=K7E4D2 K7E4D2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008510.3|UniProtKB=F7FG29 F7FG29 PTHR46690:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 6 HOMOLOG CYTOCHROME C OXIDASE ASSEMBLY FACTOR 6 HOMOLOG disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000016804.4|UniProtKB=F7FVJ3 F7FVJ3 PCMT1 PTHR11579:SF7 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;O-methyltransferase activity#GO:0008171 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 methyltransferase#PC00155;transferase#PC00220 MONDO|Ensembl=ENSMODG00000020478.3|UniProtKB=F7FIX4 F7FIX4 MYF5 PTHR11534:SF3 MYOGENIC FACTOR MYOGENIC FACTOR 5 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;striated muscle tissue development#GO:0014706;muscle organ development#GO:0007517;animal organ development#GO:0048513;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;skeletal muscle tissue development#GO:0007519;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;tissue development#GO:0009888;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;muscle tissue development#GO:0060537;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000024587.3|UniProtKB=F6PFW5 F6PFW5 PTHR23153:SF38 UBX-RELATED UBX DOMAIN-CONTAINING PROTEIN 6 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000019486.4|UniProtKB=F6WA99 F6WA99 MYLK2 PTHR24347:SF373 SERINE/THREONINE-PROTEIN KINASE MYOSIN LIGHT CHAIN KINASE 2, SKELETAL_CARDIAC MUSCLE binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;myosin binding#GO:0017022;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;cytoskeletal protein binding#GO:0008092;catalytic activity, acting on a protein#GO:0140096 heart morphogenesis#GO:0003007;cellular response to stimulus#GO:0051716;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;striated muscle contraction#GO:0006941;cell communication#GO:0007154;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;system development#GO:0048731;muscle tissue development#GO:0060537;multicellular organismal process#GO:0032501;tissue development#GO:0009888;biological regulation#GO:0065007;developmental process#GO:0032502;muscle contraction#GO:0006936;cardiac muscle tissue development#GO:0048738;system process#GO:0003008;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;signal transduction#GO:0007165;cellular process#GO:0009987;heart development#GO:0007507;muscle organ development#GO:0007517;striated muscle tissue development#GO:0014706;multicellular organism development#GO:0007275;animal organ development#GO:0048513 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877;Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514 MONDO|Ensembl=ENSMODG00000040995.1|UniProtKB=A0A5F8HF19 A0A5F8HF19 LOC100025196 PTHR26454:SF59 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005416.3|UniProtKB=F7FVE9 F7FVE9 LOC100026693 PTHR11681:SF16 NEUROPHYSIN MESOTOCIN_NEUROPHYSIN I PREPROPEPTIDE receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;neuropeptide hormone activity#GO:0005184;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 peptide hormone#PC00179;neuropeptide#PC00162 MONDO|Ensembl=ENSMODG00000000355.3|UniProtKB=F6RUA2 F6RUA2 FUT11 PTHR11929:SF198 ALPHA- 1,3 -FUCOSYLTRANSFERASE GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 4 catalytic activity#GO:0003824;transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;alpha-(1->3)-fucosyltransferase activity#GO:0046920 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000015866.4|UniProtKB=F7BRB3 F7BRB3 EMC1 PTHR21573:SF0 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1 membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;EMC complex#GO:0072546;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000008077.4|UniProtKB=F6YJP0 F6YJP0 CCDC38 PTHR21683:SF7 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 38 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000012160.3|UniProtKB=F7CYL1 F7CYL1 LINS1 PTHR16057:SF1 WINS1, 2 PROTEIN PROTEIN LINES HOMOLOG 1 MONDO|Ensembl=ENSMODG00000038974.1|UniProtKB=A0A5F8HHS1 A0A5F8HHS1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010704.4|UniProtKB=F7GH68 F7GH68 SGSM2 PTHR22957:SF194 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000011284.2|UniProtKB=F6WZI7 F6WZI7 POLE4 PTHR10252:SF79 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED DNA POLYMERASE EPSILON SUBUNIT 4 DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;epsilon DNA polymerase complex#GO:0008622;membraneless organelle#GO:0043228;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ISWI-type complex#GO:0031010 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000008532.4|UniProtKB=F7DHF2 F7DHF2 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019540.4|UniProtKB=A0A5F8HAN2 A0A5F8HAN2 GPBP1 PTHR14339:SF11 VASCULIN VASCULIN DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000014382.3|UniProtKB=A0A5F8GQG9 A0A5F8GQG9 ERGIC2 PTHR10984:SF30 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 2 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000041214.1|UniProtKB=A0A5F8HI49 A0A5F8HI49 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000003854.4|UniProtKB=F7DU33 F7DU33 FRRS1 PTHR45828:SF3 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE FERRIC REDUCTASE 1 oxidoreductase activity, acting on metal ions#GO:0016722;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771 membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000013334.3|UniProtKB=F7GAH2 F7GAH2 LOC130455237 PTHR12850:SF5 40S RIBOSOMAL PROTEIN S25 SMALL RIBOSOMAL SUBUNIT PROTEIN ES25 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000023567.1|UniProtKB=F7G1R5 F7G1R5 LOC100010544 PTHR26453:SF161 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T29-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012380.3|UniProtKB=F6PQ90 F6PQ90 C2orf69 PTHR31296:SF1 UPF0565 PROTEIN C2ORF69 MITOCHONDRIAL PROTEIN C2ORF69 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000025351.2|UniProtKB=F7FUK0 F7FUK0 AQP7 PTHR11071:SF490 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000012371.4|UniProtKB=F7DHK3 F7DHK3 CNDP2 PTHR43270:SF11 BETA-ALA-HIS DIPEPTIDASE CYTOSOLIC NON-SPECIFIC DIPEPTIDASE peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000002626.4|UniProtKB=F7FUC1 F7FUC1 RPS6KA5 PTHR24351:SF115 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-5 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;signaling#GO:0023052;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;TORC1 signaling#GO:0038202;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of nucleobase-containing compound metabolic process#GO:0019219;TOR signaling#GO:0031929;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 protein modifying enzyme#PC00260 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;p38 MAPK pathway#P05918>MSK1#P06040;PDGF signaling pathway#P00047>p90RSK#P01142 MONDO|Ensembl=ENSMODG00000008083.4|UniProtKB=F6YJ40 F6YJ40 SBF2 PTHR10807:SF4 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 13 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;phosphoric ester hydrolase activity#GO:0042578;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;dephosphorylation#GO:0016311;lipid modification#GO:0030258 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000002104.4|UniProtKB=F6UGU0 F6UGU0 SLC41A2 PTHR16228:SF25 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SOLUTE CARRIER FAMILY 41 MEMBER 2 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000012672.2|UniProtKB=A0A5F8H6H4 A0A5F8H6H4 PTHR15104:SF0 DIHYDROPTERIDINE REDUCTASE DIHYDROPTERIDINE REDUCTASE small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;biosynthetic process#GO:0009058;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000009038.3|UniProtKB=F7B277 F7B277 LOC100010714 PTHR26453:SF125 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003528.4|UniProtKB=F7GBU4 F7GBU4 AGMAT PTHR11358:SF26 ARGINASE/AGMATINASE GUANIDINO ACID HYDROLASE, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 amine metabolic process#GO:0009308;metabolic process#GO:0008152;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;polyamine biosynthetic process#GO:0006596;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000006779.5|UniProtKB=A0A5F8GCI9 A0A5F8GCI9 LOC100010569 PTHR24056:SF599 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 11A-RELATED protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of mRNA processing#GO:0050684;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000001298.4|UniProtKB=F7EWK3 F7EWK3 MTCL2 PTHR15742:SF1 GIRDIN MICROTUBULE CROSS-LINKING FACTOR 2 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 regulation of metabolic process#GO:0019222;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of catabolic process#GO:0009894;biological regulation#GO:0065007 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000011794.4|UniProtKB=F7CBT3 F7CBT3 CCNI PTHR10177:SF187 CYCLINS CYCLIN-I enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307 kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000002100.4|UniProtKB=F7G6D3 F7G6D3 SLC24A4 PTHR10846:SF21 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 4 antiporter activity#GO:0015297;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 sensory perception of smell#GO:0007608;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;sensory perception#GO:0007600;inorganic ion homeostasis#GO:0098771;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;system process#GO:0003008;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;sensory perception of chemical stimulus#GO:0007606;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000047517.1|UniProtKB=F6PJW5 F6PJW5 LOC100618274 PTHR26453:SF108 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007612.2|UniProtKB=A0A5F8HDL1 A0A5F8HDL1 PTHR12430:SF2 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 HOMOLOG protein localization to mitochondrion#GO:0070585;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;mitochondrial transport#GO:0006839;establishment of RNA localization#GO:0051236;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;intracellular transport#GO:0046907;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane translocase complex#GO:0005742 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000006717.4|UniProtKB=F7ACR7 F7ACR7 ERN2 PTHR13954:SF15 IRE1-RELATED SERINE_THREONINE-PROTEIN KINASE_ENDORIBONUCLEASE IRE2 nuclease activity#GO:0004518;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640 response to unfolded protein#GO:0006986;cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress#GO:0070059;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell death#GO:0008219;apoptotic process#GO:0006915;apoptotic signaling pathway#GO:0097190;biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;signal transduction#GO:0007165;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020 transmembrane signal receptor#PC00197;tyrosine protein kinase receptor#PC00233 Alzheimer disease-presenilin pathway#P00004>Ire-1#P00144;Alzheimer disease-presenilin pathway#P00004>Ire-1 C-terminal fragment#P00125;Alzheimer disease-presenilin pathway#P00004>Ire-1 N-terminal fragment#P00110 MONDO|Ensembl=ENSMODG00000042026.1|UniProtKB=A0A5F8GV09 A0A5F8GV09 PTHR11387:SF12 CYTOCHROME C OXIDASE SUBUNIT 6B CYTOCHROME C OXIDASE SUBUNIT 6B2 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176;oxidase#PC00175 MONDO|Ensembl=ENSMODG00000002269.4|UniProtKB=F7CVX4 F7CVX4 DNASE1L3 PTHR11371:SF32 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE GAMMA catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 programmed cell death#GO:0012501;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;cell death#GO:0008219;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;catabolic process#GO:0009056;cell differentiation#GO:0030154;cell development#GO:0048468;DNA catabolic process#GO:0006308;anatomical structure development#GO:0048856;cellular component disassembly#GO:0022411;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 endodeoxyribonuclease#PC00093 MONDO|Ensembl=ENSMODG00000018610.4|UniProtKB=A0A5F8GXQ6 A0A5F8GXQ6 CLSTN2 PTHR14139:SF3 CALSYNTENIN CALSYNTENIN-2 cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;regulation of biological quality#GO:0065008;positive regulation of cellular component organization#GO:0051130;cell adhesion#GO:0007155;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;regulation of synapse assembly#GO:0051963;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of synapse assembly#GO:0051965;positive regulation of developmental process#GO:0051094 postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000021004.4|UniProtKB=F6RJC4 F6RJC4 MORC3 PTHR23336:SF17 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3. MORC FAMILY CW-TYPE ZINC FINGER PROTEIN 3 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;molecular adaptor activity#GO:0060090 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;antiviral innate immune response#GO:0140374;defense response to virus#GO:0051607;response to virus#GO:0009615;immune system process#GO:0002376;response to other organism#GO:0051707;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087 membraneless organelle#GO:0043228;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000001521.3|UniProtKB=F7F434 F7F434 LOC100023529 PTHR24291:SF39 CYTOCHROME P450 FAMILY 4 TAUROCHENODEOXYCHOLIC 6 ALPHA-HYDROXYLASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000021238.3|UniProtKB=F6TZV1 F6TZV1 PLS1 PTHR19961:SF27 FIMBRIN/PLASTIN PLASTIN-1 molecular adaptor activity#GO:0060090;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;actin filament#GO:0005884;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000045225.1|UniProtKB=F6Q2F2 F6Q2F2 LOC100618224 PTHR26450:SF351 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009108.4|UniProtKB=F6QQG8 F6QQG8 SLC1A5 PTHR11958:SF19 SODIUM/DICARBOXYLATE SYMPORTER-RELATED NEUTRAL AMINO ACID TRANSPORTER B(0) solute:monoatomic cation symporter activity#GO:0015294;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;acidic amino acid transmembrane transporter activity#GO:0015172;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;C4-dicarboxylate transmembrane transporter activity#GO:0015556;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 L-alpha-amino acid transmembrane transport#GO:1902475;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;L-glutamate import#GO:0051938;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;aspartate transmembrane transport#GO:0015810;cellular process#GO:0009987;dicarboxylic acid transport#GO:0006835;L-glutamate transmembrane transport#GO:0015813;amino acid transport#GO:0006865;acidic amino acid transport#GO:0015800;C4-dicarboxylate transport#GO:0015740;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;import into cell#GO:0098657;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000003667.2|UniProtKB=F7ABU5 F7ABU5 IFN3 PTHR11691:SF37 TYPE I INTERFERON INTERFERON OMEGA-1 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;cytokine activity#GO:0005125;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677 cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;T cell activation#GO:0042110;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;type I interferon-mediated signaling pathway#GO:0060337;B cell activation involved in immune response#GO:0002312;immune system process#GO:0002376;cell activation involved in immune response#GO:0002263;response to peptide#GO:1901652;cellular process#GO:0009987;signal transduction#GO:0007165;lymphocyte activation involved in immune response#GO:0002285;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;T cell activation involved in immune response#GO:0002286;defense response to other organism#GO:0098542;lymphocyte activation#GO:0046649;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;natural killer cell activation#GO:0030101;immune effector process#GO:0002252;leukocyte activation involved in immune response#GO:0002366;humoral immune response#GO:0006959;B cell activation#GO:0042113;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cell activation#GO:0001775;cytokine-mediated signaling pathway#GO:0019221;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;immune response#GO:0006955;adaptive immune response#GO:0002250;response to other organism#GO:0051707;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interferon superfamily#PC00127;cytokine#PC00083 MONDO|Ensembl=ENSMODG00000001951.4|UniProtKB=F6VJP3 F6VJP3 MKNK1 PTHR24349:SF114 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-INTERACTING SERINE_THREONINE-PROTEIN KINASE 1 catalytic activity, acting on a protein#GO:0140096;calmodulin binding#GO:0005516;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;calcium/calmodulin-dependent protein kinase activity#GO:0004683 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Oxidative stress response#P00046>MNK1/2#P01137;Interleukin signaling pathway#P00036>MNK1/2#P00972;PDGF signaling pathway#P00047>MNK1/2#P01149;p38 MAPK pathway#P05918>MNK1#P06018 MONDO|Ensembl=ENSMODG00000016666.3|UniProtKB=F7E6R6 F7E6R6 MRPL28 PTHR13528:SF3 39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000001409.4|UniProtKB=F7BD34 F7BD34 REV1 PTHR45990:SF1 DNA REPAIR PROTEIN REV1 TRANSLESION SYNTHESIS PROTEIN REV1 DNA-directed DNA polymerase activity#GO:0003887;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;response to stimulus#GO:0050896;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA synthesis involved in DNA replication#GO:0090592;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;site of double-strand break#GO:0035861;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000021398.4|UniProtKB=F7CVJ3 F7CVJ3 RTTN PTHR31691:SF1 ROTATIN ROTATIN microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;organelle assembly#GO:0070925;centriole replication#GO:0007099;cell projection organization#GO:0030030;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization or biogenesis#GO:0071840;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;plasma membrane bounded cell projection#GO:0120025;centriole#GO:0005814;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000011408.3|UniProtKB=F6S5Q2 F6S5Q2 ASNSD1 PTHR45937:SF2 ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1 ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1 muscle tissue development#GO:0060537;connective tissue development#GO:0061448;anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;muscle organ development#GO:0007517;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;muscle structure development#GO:0061061;tissue development#GO:0009888;skeletal muscle tissue development#GO:0007519 MONDO|Ensembl=ENSMODG00000050837.1|UniProtKB=A0A5F8GHE0 A0A5F8GHE0 PTHR26450:SF138 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021239.4|UniProtKB=A0A5F8GPI0 A0A5F8GPI0 TRPC1 PTHR10117:SF56 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 1 monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;metal ion transport#GO:0030001;homeostatic process#GO:0042592;regulation of cytosolic calcium ion concentration#GO:0051480;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 MONDO|Ensembl=ENSMODG00000023625.2|UniProtKB=F6ZLL1 F6ZLL1 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015778.3|UniProtKB=F6Z4F6 F6Z4F6 CCNF PTHR10177:SF496 CYCLINS CYCLIN-F cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 transferase complex#GO:1990234;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000020512.4|UniProtKB=A0A5F8GW85 A0A5F8GW85 PTHR23119:SF5 DISCS LARGE DISKS LARGE HOMOLOG 1 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;signaling receptor binding#GO:0005102;binding#GO:0005488;kinase binding#GO:0019900 multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;developmental process#GO:0032502;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;anatomical structure development#GO:0048856;cell communication#GO:0007154;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;system development#GO:0048731;establishment or maintenance of apical/basal cell polarity#GO:0035088;trans-synaptic signaling#GO:0099537;protein localization to cell junction#GO:1902414;establishment or maintenance of bipolar cell polarity#GO:0061245;localization within membrane#GO:0051668;nervous system development#GO:0007399;synaptic signaling#GO:0099536;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;protein localization to synapse#GO:0035418;multicellular organism development#GO:0007275;signaling#GO:0023052;protein localization to membrane#GO:0072657;regulation of biological process#GO:0050789;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;cell adhesion#GO:0007155;receptor clustering#GO:0043113 cell junction#GO:0030054;neuromuscular junction#GO:0031594;synaptic membrane#GO:0097060;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;neuron projection#GO:0043005;cell periphery#GO:0071944;postsynaptic density membrane#GO:0098839;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;basal part of cell#GO:0045178;postsynapse#GO:0098794 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000042238.1|UniProtKB=A0A5F8GDW9 A0A5F8GDW9 PTHR34757:SF1 JUNCTIONAL PROTEIN ASSOCIATED WITH CORONARY ARTERY DISEASE JUNCTIONAL CADHERIN 5-ASSOCIATED PROTEIN regulation of cell population proliferation#GO:0042127;positive regulation of epithelial cell proliferation#GO:0050679;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cell population proliferation#GO:0008284 ruffle membrane#GO:0032587;adherens junction#GO:0005912;ruffle#GO:0001726;cell junction#GO:0030054;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;leading edge membrane#GO:0031256;anchoring junction#GO:0070161;cell projection membrane#GO:0031253;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000049571.1|UniProtKB=A0A5F8GPC7 A0A5F8GPC7 MYH13 PTHR45615:SF44 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-13 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146 muscle contraction#GO:0006936;muscle system process#GO:0003012;multicellular organismal process#GO:0032501;system process#GO:0003008 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000017575.3|UniProtKB=F7BS45 F7BS45 PTHR10332:SF9 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932 nucleobase-containing compound transport#GO:0015931;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000014417.3|UniProtKB=F7BH84 F7BH84 GPATCH3 PTHR14390:SF3 G PATCH DOMAIN CONTAINING PROTEIN 3 G PATCH DOMAIN-CONTAINING PROTEIN 3 regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;positive regulation of RNA metabolic process#GO:0051254;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of multicellular organismal process#GO:0051241;regulation of gene expression#GO:0010468;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of signal transduction#GO:0009966;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cytokine production#GO:0001817;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of cell communication#GO:0010648;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of signal transduction#GO:0009968;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558 MONDO|Ensembl=ENSMODG00000041170.1|UniProtKB=F7AJ17 F7AJ17 LOC100616677 PTHR26452:SF253 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10Q1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000043690.1|UniProtKB=A0A5F8GR95 A0A5F8GR95 MBOAT4 PTHR13906:SF3 PORCUPINE MEMBRANE-BOUND GHRELIN O-ACYLTRANSFERASE MBOAT4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 lipid modification#GO:0030258;lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000025578.3|UniProtKB=A0A5F8HLN0 A0A5F8HLN0 PTHR10369:SF3 60S RIBOSOMAL PROTEIN L36A/L44 RIBOSOMAL PROTEIN L36A structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000002282.4|UniProtKB=F7CVM1 F7CVM1 PTHR19325:SF317 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING COMPLEMENT DECAY-ACCELERATING FACTOR defense/immunity protein#PC00090;complement component#PC00078 MONDO|Ensembl=ENSMODG00000020546.4|UniProtKB=F7BBS9 F7BBS9 WDR19 PTHR14920:SF2 OSMOTIC AVOIDANCE ABNORMAL PROTEIN 1/WD REPEAT MEMBRANE PROTEIN WD REPEAT-CONTAINING PROTEIN 19 cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;intraciliary retrograde transport#GO:0035721;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017 cilium#GO:0005929;intraciliary transport particle#GO:0030990;intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000003276.4|UniProtKB=F7EYU1 F7EYU1 KBTBD8 PTHR24412:SF433 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 8 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007430.3|UniProtKB=F7DWL1 F7DWL1 TLN1 PTHR19981:SF7 TALIN TALIN-1 cell adhesion molecule binding#GO:0050839;signaling receptor binding#GO:0005102;binding#GO:0005488;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell adhesion#GO:0007155;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;plasma membrane#GO:0005886;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 Integrin signalling pathway#P00034>Talin#P00943 MONDO|Ensembl=ENSMODG00000004396.3|UniProtKB=F6SVN1 F6SVN1 PGLS PTHR11054:SF0 6-PHOSPHOGLUCONOLACTONASE 6-PHOSPHOGLUCONOLACTONASE 6-phosphogluconolactonase activity#GO:0017057;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;pentose-phosphate shunt#GO:0006098;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;generation of precursor metabolites and energy#GO:0006091;pentose-phosphate shunt, oxidative branch#GO:0009051;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nucleobase-containing compound metabolic process#GO:0006139 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000047162.1|UniProtKB=A0A5F8H6X9 A0A5F8H6X9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008387.4|UniProtKB=F7CDJ5 F7CDJ5 ISY1 PTHR13021:SF8 PRE-MRNA-SPLICING FACTOR ISY1 PRE-MRNA-SPLICING FACTOR ISY1 HOMOLOG nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site recognition#GO:0006376;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000006073.4|UniProtKB=F7FEZ8 F7FEZ8 TOR3A PTHR10760:SF3 TORSIN TORSIN-3A endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;organelle envelope#GO:0031967 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000015072.4|UniProtKB=F6WBY2 F6WBY2 OBSL1 PTHR35971:SF6 SI:DKEY-31G6.6 OBSCURIN-LIKE PROTEIN 1 positive regulation of cellular component organization#GO:0051130;cellular component organization#GO:0016043;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;positive regulation of cell differentiation#GO:0045597;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;cytoskeleton organization#GO:0007010;positive regulation of cell projection organization#GO:0031346;regulation of nervous system development#GO:0051960;microtubule cytoskeleton organization#GO:0000226;regulation of neurogenesis#GO:0050767;regulation of dendrite morphogenesis#GO:0048814;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of cell projection organization#GO:0031344;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000004115.3|UniProtKB=F6VDZ4 F6VDZ4 TFPT PTHR35084:SF1 TCF3 FUSION PARTNER TCF3 FUSION PARTNER DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;cell death#GO:0008219;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;cell communication#GO:0007154;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;apoptotic signaling pathway#GO:0097190 intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;Ino80 complex#GO:0031011;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000010868.3|UniProtKB=A0A5F8GW12 A0A5F8GW12 DYSF PTHR12546:SF44 FER-1-LIKE DYSFERLIN developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;response to wounding#GO:0009611;response to stress#GO:0006950;membrane fusion#GO:0061025;cellular process#GO:0009987;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;plasma membrane organization#GO:0007009;wound healing#GO:0042060;cellular component organization#GO:0016043;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468 intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;sarcolemma#GO:0042383;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000024847.3|UniProtKB=F7EBW3 F7EBW3 CCDC152 PTHR35253:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 152 COILED-COIL DOMAIN-CONTAINING PROTEIN 152 MONDO|Ensembl=ENSMODG00000014616.4|UniProtKB=A0A5F8GXV6 A0A5F8GXV6 KLHDC10 PTHR46428:SF1 KELCH DOMAIN-CONTAINING PROTEIN 10 KELCH DOMAIN-CONTAINING PROTEIN 10 regulation of response to stress#GO:0080134;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of cellular response to stress#GO:0080135;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646 MONDO|Ensembl=ENSMODG00000010507.4|UniProtKB=F7E9S8 F7E9S8 DNAJC10 PTHR44340:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 10 ENDOPLASMIC RETICULUM DISULFIDE REDUCTASE DNAJC10 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;binding#GO:0005488;protein binding#GO:0005515;protein-disulfide reductase activity#GO:0015035;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000009445.4|UniProtKB=F7FZK2 F7FZK2 SEC14L3 PTHR23324:SF62 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 3 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000009273.2|UniProtKB=F7DA26 F7DA26 SCAMP2 PTHR10687:SF7 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 2 secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;secretion by cell#GO:0032940;exocytosis#GO:0006887;transport#GO:0006810;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000012699.4|UniProtKB=F6TI03 F6TI03 DENND1B PTHR13196:SF24 DENN DOMAIN-CONTAINING DENN DOMAIN-CONTAINING PROTEIN 1B lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;binding#GO:0005488 vesicle-mediated transport#GO:0016192;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;import into cell#GO:0098657;immune response-activating signaling pathway#GO:0002757;endosomal transport#GO:0016197;cell surface receptor signaling pathway#GO:0007166;endocytosis#GO:0006897;response to stimulus#GO:0050896;endocytic recycling#GO:0032456;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;cellular localization#GO:0051641;immune system process#GO:0002376;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;T cell receptor signaling pathway#GO:0050852;transport#GO:0006810;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;localization#GO:0051179;regulation of immune response#GO:0050776;localization within membrane#GO:0051668 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000013007.4|UniProtKB=F7C848 F7C848 PTHR11860:SF37 POLYMERIC-IMMUNOGLOBULIN RECEPTOR TREM-LIKE TRANSCRIPT 1 PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;hemostasis#GO:0007599;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;regulation of cellular process#GO:0050794;cell activation#GO:0001775;wound healing#GO:0042060;regulation of biological quality#GO:0065008;cell communication#GO:0007154;coagulation#GO:0050817;signal transduction#GO:0007165;cellular process#GO:0009987;response to wounding#GO:0009611;response to stress#GO:0006950;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood coagulation#GO:0007596;platelet activation#GO:0030168 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000001258.4|UniProtKB=F7CJ42 F7CJ42 SLC5A2 PTHR11819:SF145 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER 2 solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;sugar transmembrane transporter activity#GO:0051119;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293 transport#GO:0006810;carbohydrate transport#GO:0008643;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;import into cell#GO:0098657;renal absorption#GO:0070293;localization#GO:0051179;system process#GO:0003008;cellular process#GO:0009987;renal system process#GO:0003014;D-glucose transmembrane transport#GO:1904659;carbohydrate transmembrane transport#GO:0034219;multicellular organismal process#GO:0032501;import across plasma membrane#GO:0098739 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000025417.2|UniProtKB=A0A5F8GZ23 A0A5F8GZ23 ZNF474 PTHR13555:SF67 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER PROTEIN 474 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004631.4|UniProtKB=A0A5F8H916 A0A5F8H916 AP3D1 PTHR22781:SF14 DELTA ADAPTIN-RELATED AP-3 COMPLEX SUBUNIT DELTA-1 protein localization to lysosome#GO:0061462;cellular component organization#GO:0016043;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;establishment of organelle localization#GO:0051656;lysosomal transport#GO:0007041;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;organelle organization#GO:0006996;protein targeting to vacuole#GO:0006623;synaptic vesicle transport#GO:0048489;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;endomembrane system organization#GO:0010256;organelle transport along microtubule#GO:0072384;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;endosomal transport#GO:0016197;vesicle organization#GO:0016050;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;protein localization to organelle#GO:0033365;protein localization to vacuole#GO:0072665;axonal transport#GO:0098930;endosome to lysosome transport#GO:0008333;organelle localization#GO:0051640;localization#GO:0051179;Golgi to vacuole transport#GO:0006896;anterograde axonal transport#GO:0008089;macromolecule localization#GO:0033036;synaptic vesicle membrane organization#GO:0048499;axo-dendritic transport#GO:0008088;vesicle localization#GO:0051648;synaptic vesicle recycling#GO:0036465;cytoskeleton-dependent intracellular transport#GO:0030705;membrane organization#GO:0061024;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;vacuolar transport#GO:0007034;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of protein localization to organelle#GO:0072594;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vesicle cytoskeletal trafficking#GO:0099518;anterograde synaptic vesicle transport#GO:0048490;intracellular protein localization#GO:0008104;vesicle budding from membrane#GO:0006900 endomembrane system#GO:0012505;membrane#GO:0016020;vesicle membrane#GO:0012506;axon terminus#GO:0043679;organelle membrane#GO:0031090;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;intracellular membrane-bounded organelle#GO:0043231;neuron projection terminus#GO:0044306;membrane protein complex#GO:0098796;vesicle#GO:0031982;membrane coat#GO:0030117;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;axon#GO:0030424;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;neuron projection#GO:0043005;presynapse#GO:0098793;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;intracellular vesicle#GO:0097708;coated membrane#GO:0048475;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000008874.4|UniProtKB=F7CAB6 F7CAB6 PTHR24006:SF647 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 12 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000008474.4|UniProtKB=F7GEK9 F7GEK9 FARP1 PTHR45858:SF2 FERM DOMAIN CONTAINING PROTEIN FERM, ARHGEF AND PLECKSTRIN DOMAIN-CONTAINING PROTEIN 1 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;guanyl-nucleotide exchange factor activity#GO:0005085 MONDO|Ensembl=ENSMODG00000018278.4|UniProtKB=F6Q6I7 F6Q6I7 GABRR2 PTHR18945:SF197 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT RHO-2 transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;chloride channel activity#GO:0005254;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836 signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;synaptic signaling#GO:0099536;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821 membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;synapse#GO:0045202;cellular anatomical structure#GO:0110165;GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;cell junction#GO:0030054 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000037855.1|UniProtKB=F6S1G7 F6S1G7 PTHR26453:SF238 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10N1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007419.4|UniProtKB=F7EE64 F7EE64 METRNL PTHR28593:SF1 METEORIN-LIKE PROTEIN METEORIN-LIKE PROTEIN signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 multicellular organismal-level homeostasis#GO:0048871;positive regulation of developmental process#GO:0051094;positive regulation of fat cell differentiation#GO:0045600;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000006990.3|UniProtKB=F6Q9X6 F6Q9X6 LOC100010241 PTHR12375:SF28 RNA-BINDING PROTEIN LUC7-RELATED RNA-BINDING PROTEIN LUC7-LIKE 2-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 gene expression#GO:0010467;cellular component assembly#GO:0022607;mRNA splice site recognition#GO:0006376;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187 Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;U2-type prespliceosome#GO:0071004;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000001434.4|UniProtKB=A0A5F8GLE9 A0A5F8GLE9 SCEL PTHR15468:SF7 ZNF185 SCIELLIN anatomical structure development#GO:0048856;tissue development#GO:0009888;epidermis development#GO:0008544;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000005859.4|UniProtKB=A0A5F8HGM4 A0A5F8HGM4 SLC44A2 PTHR12385:SF34 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000045936.1|UniProtKB=K7DYX6 K7DYX6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000001658.4|UniProtKB=F7D9F5 F7D9F5 CPNE1 PTHR10857:SF2 COPINE COPINE-1 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of response to cytokine stimulus#GO:0060759;regulation of cytokine-mediated signaling pathway#GO:0001959;regulation of response to stimulus#GO:0048583;response to metal ion#GO:0010038;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of cytokine-mediated signaling pathway#GO:0001961;positive regulation of signaling#GO:0023056;response to calcium ion#GO:0051592;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000019910.4|UniProtKB=F6VQ58 F6VQ58 SLC39A13 PTHR16950:SF16 ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4 ZINC TRANSPORTER ZIP13 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000014649.4|UniProtKB=A0A5F8G3R3 A0A5F8G3R3 PTHR23060:SF3 TESTIS EXPRESSED GENE 14 INACTIVE SERINE_THREONINE-PROTEIN KINASE TEX14 negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;male meiotic nuclear division#GO:0007140;negative regulation of chromosome segregation#GO:0051985;meiotic cell cycle#GO:0051321;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle phase transition#GO:1901988;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;negative regulation of biological process#GO:0048519;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;nuclear division#GO:0000280;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;meiotic nuclear division#GO:0140013;chromosome organization#GO:0051276;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;negative regulation of organelle organization#GO:0010639;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;regulation of mitotic sister chromatid segregation#GO:0033047;multicellular organismal reproductive process#GO:0048609;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic spindle assembly checkpoint signaling#GO:0007094;cell cycle checkpoint signaling#GO:0000075;chromosome localization#GO:0050000;regulation of cell cycle process#GO:0010564;metaphase chromosome alignment#GO:0051310;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;chromosome separation#GO:0051304;negative regulation of cell cycle#GO:0045786;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;gamete generation#GO:0007276;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;extracellular structure organization#GO:0043062;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;mitotic sister chromatid segregation#GO:0000070;regulation of mitotic cell cycle#GO:0007346;male gamete generation#GO:0048232;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;regulation of chromosome organization#GO:0033044;negative regulation of cell cycle process#GO:0010948;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;negative regulation of cellular component organization#GO:0051129;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic sister chromatid separation#GO:0051306;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;reproductive process#GO:0022414;organelle localization#GO:0051640;negative regulation of chromosome organization#GO:2001251;organelle fission#GO:0048285;cell communication#GO:0007154;localization#GO:0051179;intracellular signal transduction#GO:0035556 chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;midbody#GO:0030496;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000016988.4|UniProtKB=F6U5I5 F6U5I5 ARL13B PTHR46090:SF3 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cell periphery#GO:1990778;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;protein localization to cilium#GO:0061512;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;cellular localization#GO:0051641;non-motile cilium assembly#GO:1905515;localization#GO:0051179;cilium organization#GO:0044782;organelle assembly#GO:0070925;localization within membrane#GO:0051668 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;ciliary membrane#GO:0060170;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cell projection membrane#GO:0031253;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000024549.2|UniProtKB=F7F254 F7F254 PTHR26453:SF601 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014461.5|UniProtKB=F7FM36 F7FM36 SYTL1 PTHR45716:SF3 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;transport#GO:0006810;secretion by cell#GO:0032940;exocytosis#GO:0006887;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000018898.3|UniProtKB=F7CQR3 F7CQR3 NUDT6 PTHR13994:SF46 NUDIX HYDROLASE RELATED NUDIX HYDROLASE 6 nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265 hydrolase#PC00121;nucleotide phosphatase#PC00173 MONDO|Ensembl=ENSMODG00000008202.3|UniProtKB=F7DJ46 F7DJ46 CDYL2 PTHR43684:SF2 FAMILY NOT NAMED CHROMODOMAIN Y-LIKE PROTEIN 2 isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824 monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;microbody#GO:0042579;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777 MONDO|Ensembl=ENSMODG00000008159.4|UniProtKB=F7ELA1 F7ELA1 PSKH2 PTHR24347:SF255 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE H2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000025473.3|UniProtKB=F6QZS2 F6QZS2 NUP42 PTHR46527:SF1 NUCLEOPORIN-LIKE PROTEIN 2 NUCLEOPORIN NUP42 transporter#PC00227 MONDO|Ensembl=ENSMODG00000044652.1|UniProtKB=F7F9P8 F7F9P8 LOC100015895 PTHR11818:SF119 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN A structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;sensory system development#GO:0048880;system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;sensory organ development#GO:0007423;visual system development#GO:0150063;visual perception#GO:0007601;sensory perception of light stimulus#GO:0050953;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000006303.3|UniProtKB=F7BRQ2 F7BRQ2 ATF1 PTHR45879:SF2 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of nucleobase-containing compound metabolic process#GO:0019219;intracellular signaling cassette#GO:0141124;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;signaling#GO:0023052 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302;p38 MAPK pathway#P05918>ATF1#P06019 MONDO|Ensembl=ENSMODG00000010821.5|UniProtKB=F7BZ87 F7BZ87 GAREM1 PTHR14454:SF6 GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN FAMILY MEMBER GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;epidermal growth factor receptor signaling pathway#GO:0007173;biological regulation#GO:0065007;signal transduction#GO:0007165;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166 MONDO|Ensembl=ENSMODG00000042503.1|UniProtKB=A0A5F8HG19 A0A5F8HG19 PTHR11910:SF1 ATP SYNTHASE DELTA CHAIN ATP SYNTHASE PERIPHERAL STALK SUBUNIT OSCP, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ATP biosynthetic process#GO:0006754;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 transporter#PC00227;primary active transporter#PC00068;ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000014587.4|UniProtKB=A0A5F8GPU1 A0A5F8GPU1 KRT17 PTHR23239:SF396 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 17 structural molecule activity#GO:0005198 cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;intermediate filament organization#GO:0045109;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;cytoskeleton organization#GO:0007010;skin development#GO:0043588;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular developmental process#GO:0048869;morphogenesis of an epithelium#GO:0002009;epidermis development#GO:0008544;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000027743.2|UniProtKB=H9H680 H9H680 LOC103095949 PTHR11738:SF199 MHC CLASS I NK CELL RECEPTOR IG-LIKE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000007393.4|UniProtKB=F6YZN8 F6YZN8 PRPF39 PTHR17204:SF5 PRE-MRNA PROCESSING PROTEIN PRP39-RELATED PRE-MRNA-PROCESSING FACTOR 39 RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085 U2-type prespliceosome#GO:0071004;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000018786.5|UniProtKB=K7E5G0 K7E5G0 RPRD2 PTHR12460:SF40 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 2 RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 MONDO|Ensembl=ENSMODG00000019508.4|UniProtKB=F6VTY8 F6VTY8 PTHR14796:SF5 NEURENSIN 1-RELATED NEURENSIN-2 anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275;nervous system development#GO:0007399;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 neuron projection#GO:0043005;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell body#GO:0044297;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000005393.3|UniProtKB=F7BNP3 F7BNP3 SLC12A4 PTHR11827:SF46 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 4 chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;symporter activity#GO:0015293;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic anion transport#GO:0006820;cellular process#GO:0009987 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000014705.4|UniProtKB=A0A5F8HHZ9 A0A5F8HHZ9 ELMOD1 PTHR12771:SF18 ENGULFMENT AND CELL MOTILITY ELMO DOMAIN-CONTAINING PROTEIN 1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 cell projection#GO:0042995;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;synapse#GO:0045202;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;cilium#GO:0005929;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000046406.1|UniProtKB=A0A5F8G6K1 A0A5F8G6K1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000019592.4|UniProtKB=F6Y8P7 F6Y8P7 TNC PTHR46708:SF1 TENASCIN TENASCIN cell development#GO:0048468;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;cellular process#GO:0009987;neuron projection development#GO:0031175;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;developmental process#GO:0032502 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000012725.5|UniProtKB=A0A5F8GL01 A0A5F8GL01 MEF2A PTHR11945:SF637 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2A histone deacetylase binding#GO:0042826;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515 positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MADS box transcription factor#PC00250 p38 MAPK pathway#P05918>MEF#P06023;Oxidative stress response#P00046>MEF-2#P01128 MONDO|Ensembl=ENSMODG00000002818.4|UniProtKB=F7EJ99 F7EJ99 FBP2 PTHR11556:SF13 FRUCTOSE-1,6-BISPHOSPHATASE-RELATED FRUCTOSE-1,6-BISPHOSPHATASE ISOZYME 2 sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 glucose metabolic process#GO:0006006;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;small molecule metabolic process#GO:0044281;hexose biosynthetic process#GO:0019319;gluconeogenesis#GO:0006094;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 carbohydrate phosphatase#PC00066;hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000038381.1|UniProtKB=A0A5F8HD64 A0A5F8HD64 LOC130453492 PTHR24381:SF435 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 275 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000025347.3|UniProtKB=F6YM05 F6YM05 LOC100032503 PTHR13003:SF2 NUP107-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP107 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 cellular component organization#GO:0016043;protein import into nucleus#GO:0006606;protein transport#GO:0015031;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;organelle organization#GO:0006996;gene expression#GO:0010467;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;localization#GO:0051179;macromolecule biosynthetic process#GO:0009059;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;chromosome organization#GO:0051276;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;nuclear pore outer ring#GO:0031080;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 transporter#PC00227 MONDO|Ensembl=ENSMODG00000006409.4|UniProtKB=A0A5F8GHC7 A0A5F8GHC7 PCDH17 PTHR24028:SF41 CADHERIN-87A PROTOCADHERIN-17 cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;synapse assembly#GO:0007416;cell junction organization#GO:0034330;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;synapse organization#GO:0050808;anatomical structure development#GO:0048856;system development#GO:0048731 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 MONDO|Ensembl=ENSMODG00000038125.1|UniProtKB=F6XXY9 F6XXY9 GRB14 PTHR11243:SF22 GROWTH FACTOR RECEPTOR-BOUND PROTEIN GROWTH FACTOR RECEPTOR-BOUND PROTEIN 14 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell surface receptor signaling pathway#GO:0007166;response to hormone#GO:0009725;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;negative regulation of signal transduction#GO:0009968;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;cellular response to insulin stimulus#GO:0032869;cellular response to nitrogen compound#GO:1901699;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Grb14#P00197 MONDO|Ensembl=ENSMODG00000028946.2|UniProtKB=K7E0F9 K7E0F9 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000014247.4|UniProtKB=A0A5F8HBM2 A0A5F8HBM2 FBXO25 PTHR13123:SF8 LD30288P F-BOX ONLY PROTEIN 25 cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000008666.5|UniProtKB=A0A5F8GZ97 A0A5F8GZ97 PRSS16 PTHR11010:SF123 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED THYMUS-SPECIFIC SERINE PROTEASE endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000013771.4|UniProtKB=A0A5F8HK86 A0A5F8HK86 FANCE PTHR32094:SF5 FANCONI ANEMIA GROUP E PROTEIN FANCONI ANEMIA GROUP E PROTEIN nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Fanconi anaemia nuclear complex#GO:0043240;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000016103.4|UniProtKB=F7EB19 F7EB19 LRRIQ4 PTHR47186:SF61 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 57 PROTEIN LAP1 MONDO|Ensembl=ENSMODG00000012796.4|UniProtKB=A0A5F8H4Y1 A0A5F8H4Y1 ARRDC4 PTHR11188:SF16 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 4 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000020119.2|UniProtKB=F7DRG6 F7DRG6 OR6Q1 PTHR26452:SF19 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010962.4|UniProtKB=F7BC48 F7BC48 CLCN6 PTHR11689:SF158 CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER H(+)_CL(-) EXCHANGE TRANSPORTER 6 gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821;monoatomic anion transport#GO:0006820 intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane#GO:0016020;lysosomal membrane#GO:0005765;endomembrane system#GO:0012505;late endosome#GO:0005770;vacuole#GO:0005773;cytoplasm#GO:0005737;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000021402.3|UniProtKB=F7CVH0 F7CVH0 TMX3 PTHR46426:SF1 PROTEIN DISULFIDE-ISOMERASE TMX3 PROTEIN DISULFIDE-ISOMERASE TMX3 organelle#GO:0043226;cell surface#GO:0009986;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000051109.1|UniProtKB=A0A5F8HGE2 A0A5F8HGE2 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009592.2|UniProtKB=A0A5F8H3E4 A0A5F8H3E4 REEP4 PTHR12300:SF36 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 4 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum tubular network organization#GO:0071786;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;cytoplasmic microtubule#GO:0005881;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;endoplasmic reticulum tubular network#GO:0071782;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoskeleton#GO:0005856 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000047305.1|UniProtKB=A0A5F8GDM4 A0A5F8GDM4 LOC100024823 PTHR39235:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Y PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Y enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629 membrane protein complex#GO:0098796;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 transferase#PC00220 MONDO|Ensembl=ENSMODG00000005397.3|UniProtKB=F7G6D0 F7G6D0 LOC107648878 PTHR26454:SF2 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6E1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010881.4|UniProtKB=F7FJF7 F7FJF7 LOC100028437 PTHR14885:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43 cell projection organization#GO:0030030;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cilium assembly#GO:0060271;cellular component organization#GO:0016043;sperm motility#GO:0097722;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;spermatogenesis#GO:0007283 cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000048371.1|UniProtKB=A0A5F8H9R5 A0A5F8H9R5 LOC130458047 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000009713.4|UniProtKB=F6XT73 F6XT73 FHIP2A PTHR21705:SF10 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK INTERACTING PROTEIN 2A MONDO|Ensembl=ENSMODG00000029578.2|UniProtKB=K7E1F2 K7E1F2 PTHR23267:SF157 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR DELTA VARIABLE 2 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000024809.1|UniProtKB=F7C5M9 F7C5M9 PTHR24253:SF181 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233 protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000000324.4|UniProtKB=H9H5W4 H9H5W4 PTHR44819:SF1 V-TYPE IMMUNOGLOBULIN DOMAIN-CONTAINING SUPPRESSOR OF T-CELL ACTIVATION V-TYPE IMMUNOGLOBULIN DOMAIN-CONTAINING SUPPRESSOR OF T-CELL ACTIVATION biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;negative regulation of cell-cell adhesion#GO:0022408;negative regulation of cell adhesion#GO:0007162;regulation of cell adhesion#GO:0030155;regulation of T cell activation#GO:0050863;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;negative regulation of cell activation#GO:0050866;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of lymphocyte activation#GO:0051249;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of T cell activation#GO:0050868 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000003742.2|UniProtKB=F7ECV1 F7ECV1 PTHR36863:SF1 SHIELDIN COMPLEX SUBUNIT 1 SHIELDIN COMPLEX SUBUNIT 1 regulation of developmental process#GO:0050793;positive regulation of double-strand break repair#GO:2000781;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of leukocyte mediated immunity#GO:0002703;negative regulation of DNA recombination#GO:0045910;positive regulation of DNA metabolic process#GO:0051054;regulation of double-strand break repair#GO:2000779;positive regulation of lymphocyte activation#GO:0051251;positive regulation of biosynthetic process#GO:0009891;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;regulation of immune response#GO:0050776;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of cell activation#GO:0050867;negative regulation of DNA metabolic process#GO:0051053;positive regulation of DNA repair#GO:0045739;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;positive regulation of developmental process#GO:0051094;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of lymphocyte activation#GO:0051249;positive regulation of adaptive immune response#GO:0002821;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of DNA metabolic process#GO:0051052;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;regulation of cellular response to stress#GO:0080135;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of lymphocyte mediated immunity#GO:0002706;regulation of DNA recombination#GO:0000018;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of B cell activation#GO:0050864;positive regulation of immune system process#GO:0002684;negative regulation of double-strand break repair via homologous recombination#GO:2000042;positive regulation of leukocyte activation#GO:0002696 site of double-strand break#GO:0035861;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734 MONDO|Ensembl=ENSMODG00000004644.4|UniProtKB=A0A5F8H631 A0A5F8H631 MTARC1 PTHR14237:SF25 MOLYBDOPTERIN COFACTOR SULFURASE MOSC MITOCHONDRIAL AMIDOXIME-REDUCING COMPONENT 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;nitrate metabolic process#GO:0042126 MONDO|Ensembl=ENSMODG00000024968.1|UniProtKB=F6QMG1 F6QMG1 LOC100018015 PTHR10369:SF3 60S RIBOSOMAL PROTEIN L36A/L44 RIBOSOMAL PROTEIN L36A structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000029059.1|UniProtKB=K7E1T1 K7E1T1 LOC100011820 PTHR11214:SF151 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000028192.2|UniProtKB=K7DYX4 K7DYX4 GOLGA7B PTHR13254:SF2 GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A, 7 GOLGIN SUBFAMILY A MEMBER 7B establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein targeting#GO:0006605;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000013932.3|UniProtKB=F6SCS3 F6SCS3 SOX3 PTHR10270:SF111 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-3 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;head development#GO:0060322;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 MONDO|Ensembl=ENSMODG00000019193.4|UniProtKB=F7A8Z0 F7A8Z0 EREG PTHR10740:SF11 TRANSFORMING GROWTH FACTOR ALPHA PROEPIREGULIN molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 ERBB signaling pathway#GO:0038127;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of cell cycle#GO:0045787;regulation of nuclear division#GO:0051783;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;positive regulation of mitotic nuclear division#GO:0045840;regulation of mitotic nuclear division#GO:0007088;positive regulation of cell population proliferation#GO:0008284;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;signaling#GO:0023052;positive regulation of cellular component organization#GO:0051130;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of organelle organization#GO:0010638;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 MONDO|Ensembl=ENSMODG00000021548.3|UniProtKB=F7DF17 F7DF17 PPP1R13L PTHR24164:SF5 RELA-ASSOCIATED INHIBITOR RELA-ASSOCIATED INHIBITOR regulation of biological process#GO:0050789;regulation of developmental process#GO:0050793;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of developmental process#GO:0051094;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 MONDO|Ensembl=ENSMODG00000014604.4|UniProtKB=F6ZEM0 F6ZEM0 PDPR PTHR13847:SF193 SARCOSINE DEHYDROGENASE-RELATED PYRUVATE DEHYDROGENASE PHOSPHATASE REGULATORY SUBUNIT, MITOCHONDRIAL membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000049495.1|UniProtKB=K7E0J9 K7E0J9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010775.4|UniProtKB=F7CIU0 F7CIU0 RNASEH2B PTHR13383:SF11 RIBONUCLEASE H2 SUBUNIT B RIBONUCLEASE H2 SUBUNIT B macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 endoribonuclease#PC00094;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000000138.4|UniProtKB=F7EXL4 F7EXL4 LOC100032873 PTHR47015:SF1 BPI FOLD-CONTAINING FAMILY A MEMBER 1 BPI FOLD-CONTAINING FAMILY A MEMBER 1 chemical homeostasis#GO:0048878;homeostatic process#GO:0042592;multicellular organismal-level homeostasis#GO:0048871;multicellular organismal process#GO:0032501 MONDO|Ensembl=ENSMODG00000029146.2|UniProtKB=K7E0A2 K7E0A2 PTHR10201:SF136 MATRIX METALLOPROTEINASE HEMOPEXIN catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;extracellular structure organization#GO:0043062;porphyrin-containing compound metabolic process#GO:0006778;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;pigment metabolic process#GO:0042440;cellular process#GO:0009987;catabolic process#GO:0009056;heme metabolic process#GO:0042168 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000016279.4|UniProtKB=F7AUM6 F7AUM6 ICA1L PTHR10164:SF5 ISLET CELL AUTOANTIGEN 1 ISLET CELL AUTOANTIGEN 1-LIKE PROTEIN molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular component organization#GO:0016043;membrane organization#GO:0061024;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular component organization or biogenesis#GO:0071840;regulation of secretion#GO:0051046 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000027326.2|UniProtKB=K7E637 K7E637 PTHR23120:SF42 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT FAMILY MEMBER 3 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000003065.4|UniProtKB=F6PLX5 F6PLX5 PCYT2 PTHR45780:SF2 ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;nucleotidyltransferase#PC00174 MONDO|Ensembl=ENSMODG00000018781.4|UniProtKB=F7AD95 F7AD95 PTHR35441:SF1 CIRCADIAN-ASSOCIATED TRANSCRIPTIONAL REPRESSOR CIRCADIAN-ASSOCIATED TRANSCRIPTIONAL REPRESSOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 negative regulation of biological process#GO:0048519;circadian regulation of gene expression#GO:0032922;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;rhythmic process#GO:0048511;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;circadian rhythm#GO:0007623;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000013658.4|UniProtKB=F6TY10 F6TY10 YWHAG PTHR18860:SF22 14-3-3 PROTEIN 14-3-3 PROTEIN GAMMA enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;protein binding#GO:0005515 scaffold/adaptor protein#PC00226 FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539;Parkinson disease#P00049>14-3-3#P01238 MONDO|Ensembl=ENSMODG00000012005.3|UniProtKB=F7AMK3 F7AMK3 NEIL2 PTHR22993:SF29 FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE ENDONUCLEASE 8-LIKE 2 DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;DNA N-glycosylase activity#GO:0019104;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536 metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA glycosylase#PC00010 MONDO|Ensembl=ENSMODG00000020221.3|UniProtKB=F7FXJ0 F7FXJ0 MBLAC2 PTHR42951:SF4 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING ACYL-COENZYME A THIOESTERASE MBLAC2 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000013011.4|UniProtKB=A0A5F8GXK1 A0A5F8GXK1 MED24 PTHR12898:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 24 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 24 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription initiation#GO:2000142;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000013360.4|UniProtKB=F7FDG7 F7FDG7 PTHR13944:SF18 AGAP007712-PA A-KINASE ANCHOR PROTEIN 13 signaling adaptor activity#GO:0035591;enzyme regulator activity#GO:0030234;protein-macromolecule adaptor activity#GO:0030674;guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;structural molecule activity#GO:0005198;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;MAP kinase scaffold activity#GO:0005078;protein complex scaffold activity#GO:0140378;molecular adaptor activity#GO:0060090 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of MAPK cascade#GO:0043410;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;positive regulation of response to stimulus#GO:0048584 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000021053.4|UniProtKB=F6VJK2 F6VJK2 RCAN1 PTHR10300:SF4 CALCIPRESSIN CALCIPRESSIN-1 phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000002164.4|UniProtKB=A0A5F8HGI5 A0A5F8HGI5 CFDP1 PTHR48407:SF1 CRANIOFACIAL DEVELOPMENT PROTEIN 1 HETEROCHROMATIN-STABILIZING PROTEIN CFDP1 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;Swr1 complex#GO:0000812;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000048581.1|UniProtKB=A0A5F8HK11 A0A5F8HK11 COX16 PTHR17130:SF14 MITOCHONDRIAL OUTER MEMBRANE PROTEIN 25 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX16 HOMOLOG, MITOCHONDRIAL respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000014661.4|UniProtKB=F7EPX6 F7EPX6 PLIN2 PTHR14024:SF25 PERILIPIN PERILIPIN-2 regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;lipid storage#GO:0019915;cellular process#GO:0009987;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of localization#GO:0032879 cytosol#GO:0005829;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017743.3|UniProtKB=F7EKW4 F7EKW4 SERINC1 PTHR10383:SF15 SERINE INCORPORATOR SERINE INCORPORATOR 1 cellular anatomical structure#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000019753.4|UniProtKB=F6WN79 F6WN79 RPL35 PTHR45722:SF2 60S RIBOSOMAL PROTEIN L35 LARGE RIBOSOMAL SUBUNIT PROTEIN UL29 RNA binding#GO:0003723;structural molecule activity#GO:0005198;mRNA binding#GO:0003729;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488 metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000002539.4|UniProtKB=F7AM32 F7AM32 IRF6 PTHR11949:SF9 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000021107.4|UniProtKB=A0A5F8GTQ0 A0A5F8GTQ0 SRPX PTHR46343:SF1 HYR DOMAIN-CONTAINING PROTEIN SUSHI REPEAT-CONTAINING PROTEIN SRPX localization#GO:0051179;vacuole organization#GO:0007033;organelle assembly#GO:0070925;endocytosis#GO:0006897;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;vesicle organization#GO:0016050;phagolysosome assembly#GO:0001845;phagocytosis#GO:0006909;transport#GO:0006810;lytic vacuole organization#GO:0080171;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;lysosome organization#GO:0007040;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000009801.3|UniProtKB=F6SYD0 F6SYD0 KIAA1549L PTHR21590:SF3 SEA DOMAIN-CONTAINING PROTEIN UPF0606 PROTEIN KIAA1549L MONDO|Ensembl=ENSMODG00000049950.1|UniProtKB=A0A5F8GN68 A0A5F8GN68 KCNMB1 PTHR10258:SF1 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-1 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106 biological regulation#GO:0065007;potassium ion transport#GO:0006813;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;cellular process#GO:0009987;detection of stimulus#GO:0051606;transmission of nerve impulse#GO:0019226;system process#GO:0003008;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;response to metal ion#GO:0010038;transport#GO:0006810;metal ion transport#GO:0030001;response to stimulus#GO:0050896;action potential#GO:0001508;detection of chemical stimulus#GO:0009593;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cell communication#GO:0007154;response to calcium ion#GO:0051592;monoatomic cation transport#GO:0006812;localization#GO:0051179;nervous system process#GO:0050877 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000007992.2|UniProtKB=F7D5E0 F7D5E0 RNF222 PTHR47095:SF1 RING FINGER PROTEIN 222 RING FINGER PROTEIN 222 MONDO|Ensembl=ENSMODG00000000083.4|UniProtKB=F6QSU2 F6QSU2 STIM2 PTHR15136:SF2 STROMAL INTERACTION MOLECULE HOMOLOG STROMAL INTERACTION MOLECULE 2 molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246;cation binding#GO:0043169;channel regulator activity#GO:0016247;metal ion binding#GO:0046872;transporter regulator activity#GO:0141108;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;monoatomic ion homeostasis#GO:0050801 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000003239.5|UniProtKB=F6THV8 F6THV8 HEMGN PTHR15993:SF6 HEMOGEN HEMOGEN regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of cell differentiation#GO:0045595 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000008711.4|UniProtKB=F6PVZ2 F6PVZ2 DCAF17 PTHR14815:SF2 DDB1- AND CUL4-ASSOCIATED FACTOR 17 DDB1- AND CUL4-ASSOCIATED FACTOR 17 intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000039124.1|UniProtKB=A0A5F8GVL6 A0A5F8GVL6 PTHR22923:SF126 CEREBELLIN-RELATED CAPRIN-2 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014786.4|UniProtKB=F7G6S7 F7G6S7 KCNH8 PTHR10217:SF380 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED DELAYED RECTIFIER POTASSIUM CHANNEL KCNH8 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267 metal ion transport#GO:0030001;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of membrane potential#GO:0042391;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000018968.4|UniProtKB=A0A5F8HES0 A0A5F8HES0 LRP1 PTHR24270:SF23 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROLOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;catabolic process#GO:0009056;cellular process#GO:0009987;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;transport#GO:0006810;phagocytosis#GO:0006909;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 apolipoprotein#PC00052;transfer/carrier protein#PC00219 Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112 MONDO|Ensembl=ENSMODG00000009885.4|UniProtKB=F6VCZ9 F6VCZ9 PTHR24064:SF34 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 20 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000013559.5|UniProtKB=F6R0H2 F6R0H2 DMXL1 PTHR13950:SF12 RABCONNECTIN-RELATED DMX-LIKE PROTEIN 1 intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;endosomal transport#GO:0016197;cellular component biogenesis#GO:0044085;early endosome to late endosome transport#GO:0045022;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000008953.3|UniProtKB=F7GCP6 F7GCP6 MTMR9 PTHR10807:SF56 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 9 protein binding#GO:0005515;hydrolase activity#GO:0016787;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899;phosphoric ester hydrolase activity#GO:0042578;protein phosphatase binding#GO:0019903;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 phospholipid metabolic process#GO:0006644;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;glycerolipid metabolic process#GO:0046486;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;negative regulation of catabolic process#GO:0009895;dephosphorylation#GO:0016311;phosphatidylinositol dephosphorylation#GO:0046856;biological regulation#GO:0065007;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;organophosphate metabolic process#GO:0019637;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;lipid modification#GO:0030258;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152 membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000017212.2|UniProtKB=F6XES0 F6XES0 CLTRN PTHR46884:SF1 COLLECTRIN COLLECTRIN EGF receptor signaling pathway#P00018>Ras#P00552 MONDO|Ensembl=ENSMODG00000038570.1|UniProtKB=A0A5F8G7U4 A0A5F8G7U4 SRP9 PTHR12834:SF12 SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN protein targeting#GO:0006605;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;protein targeting to membrane#GO:0006612;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;localization within membrane#GO:0051668 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000011453.4|UniProtKB=F6W177 F6W177 TMCO6 PTHR16356:SF1 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 TMCO6 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 MONDO|Ensembl=ENSMODG00000007671.4|UniProtKB=F7FNI6 F7FNI6 PLD3 PTHR10185:SF16 PHOSPHOLIPASE D - RELATED 5'-3' EXONUCLEASE PLD3 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000015868.4|UniProtKB=F7F077 F7F077 PTHR13814:SF12 FETUIN KININOGEN-1 peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 negative regulation of wound healing#GO:0061045;regulation of response to wounding#GO:1903034;regulation of hemostasis#GO:1900046;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of cell adhesion#GO:0030155;regulation of coagulation#GO:0050818;negative regulation of cell adhesion#GO:0007162;regulation of multicellular organismal process#GO:0051239;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;negative regulation of blood coagulation#GO:0030195;regulation of response to stimulus#GO:0048583;negative regulation of response to wounding#GO:1903035;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;regulation of wound healing#GO:0061041;negative regulation of hemostasis#GO:1900047;negative regulation of coagulation#GO:0050819;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>Bradykinin#P00438;Blood coagulation#P00011>HMWK#P00413;Blood coagulation#P00011>Kininogen#P00451 MONDO|Ensembl=ENSMODG00000002043.4|UniProtKB=F6QCA4 F6QCA4 SRD5A1 PTHR10556:SF57 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;regulation of biological quality#GO:0065008;steroid biosynthetic process#GO:0006694;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;hormone biosynthetic process#GO:0042446;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;lipid biosynthetic process#GO:0008610 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000017701.5|UniProtKB=F7FUU4 F7FUU4 HEY2 PTHR10985:SF88 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY_ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cell surface receptor signaling pathway#GO:0007166;anterior/posterior pattern specification#GO:0009952;regulation of multicellular organismal process#GO:0051239;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;animal gross anatomical part developmental process#GO:0160108;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;circulatory system development#GO:0072359;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cell communication#GO:0007154;pattern specification process#GO:0007389;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 MONDO|Ensembl=ENSMODG00000009614.5|UniProtKB=F6S005 F6S005 HR PTHR12549:SF4 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN LYSINE-SPECIFIC DEMETHYLASE HAIRLESS nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;histone demethylase activity#GO:0032452;chromatin DNA binding#GO:0031490;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;protein demethylase activity#GO:0140457 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000010012.4|UniProtKB=F6UAT4 F6UAT4 BMP6 PTHR11848:SF137 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 6 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;developmental process#GO:0032502;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;response to stimulus#GO:0050896;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP6/7#P06752;TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000036945.1|UniProtKB=A0A5F8G2A7 A0A5F8G2A7 monDomV1R1277 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016721.4|UniProtKB=A0A5F8GZD8 A0A5F8GZD8 DOCK5 PTHR45653:SF3 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 5 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267 muscle structure development#GO:0061061;cell migration#GO:0016477;cell motility#GO:0048870;cell differentiation#GO:0030154;myoblast fusion#GO:0007520;cellular process#GO:0009987;muscle cell differentiation#GO:0042692;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;syncytium formation by cell-cell fusion#GO:0000768;striated muscle cell differentiation#GO:0051146;animal gross anatomical part developmental process#GO:0160108;cell-cell fusion#GO:0140253;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000001562.2|UniProtKB=F7BX66 F7BX66 ROMO1 PTHR28525:SF1 REACTIVE OXYGEN SPECIES MODULATOR 1 REACTIVE OXYGEN SPECIES MODULATOR 1 protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;macromolecule localization#GO:0033036;organelle organization#GO:0006996;membrane organization#GO:0061024;protein insertion into mitochondrial inner membrane#GO:0045039;mitochondrial protein import pathway#GO:7770058;mitochondrion organization#GO:0007005;protein import into mitochondrial matrix#GO:0030150;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000008139.4|UniProtKB=A0A5F8H2J9 A0A5F8H2J9 CRYL1 PTHR48075:SF1 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN LAMBDA-CRYSTALLIN HOMOLOG catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000002751.4|UniProtKB=F6YHE4 F6YHE4 PTHR24089:SF262 SOLUTE CARRIER FAMILY 25 SOLUTE CARRIER FAMILY 25 MEMBER 24 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 nitrogen compound transport#GO:0071705;transport#GO:0006810;carbohydrate derivative transport#GO:1901264;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;localization#GO:0051179;organophosphate ester transport#GO:0015748 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 MONDO|Ensembl=ENSMODG00000007713.4|UniProtKB=A0A5F8HFG4 A0A5F8HFG4 FCHSD2 PTHR15735:SF11 FCH AND DOUBLE SH3 DOMAINS PROTEIN F-BAR AND DOUBLE SH3 DOMAINS PROTEIN 2 phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546 regulation of anatomical structure size#GO:0090066;neuromuscular synaptic transmission#GO:0007274;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;synaptic signaling#GO:0099536;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;endocytosis#GO:0006897;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament-based process#GO:0032970;transport#GO:0006810;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;trans-synaptic signaling#GO:0099537;localization#GO:0051179;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;regulation of supramolecular fiber organization#GO:1902903;clathrin-dependent endocytosis#GO:0072583;regulation of protein polymerization#GO:0032271;anterograde trans-synaptic signaling#GO:0098916;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;neuromuscular junction#GO:0031594;cell junction#GO:0030054;recycling endosome#GO:0055037;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000048416.1|UniProtKB=F6V7E0 F6V7E0 monDomV1R1267 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009513.3|UniProtKB=F7EVJ7 F7EVJ7 PTHR10441:SF2 CD8 ALPHA CHAIN T-CELL SURFACE GLYCOPROTEIN CD8 ALPHA CHAIN lymphocyte activation#GO:0046649;antigen receptor-mediated signaling pathway#GO:0050851;T cell differentiation#GO:0030217;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;cell development#GO:0048468;leukocyte differentiation#GO:0002521;T cell activation#GO:0042110;regulation of biological process#GO:0050789;mononuclear cell differentiation#GO:1903131;immune response-regulating signaling pathway#GO:0002764;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;immune response-regulating cell surface receptor signaling pathway#GO:0002768;hemopoiesis#GO:0030097;biological regulation#GO:0065007;adaptive immune response#GO:0002250;immune response#GO:0006955;cellular developmental process#GO:0048869;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;anatomical structure development#GO:0048856;lymphocyte differentiation#GO:0030098;T cell mediated immunity#GO:0002456;regulation of immune response#GO:0050776;cell activation#GO:0001775 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 MONDO|Ensembl=ENSMODG00000004166.6|UniProtKB=F6QQ25 F6QQ25 DENND4C PTHR12296:SF17 DENN DOMAIN-CONTAINING PROTEIN 4 DENN DOMAIN-CONTAINING PROTEIN 4C guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;regulation of cell communication#GO:0010646;cellular response to peptide hormone stimulus#GO:0071375;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to peptide hormone#GO:0043434;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000049270.1|UniProtKB=A0A5F8GRV6 A0A5F8GRV6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000017333.4|UniProtKB=F6WVS4 F6WVS4 FOXO6 PTHR45767:SF5 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000003159.4|UniProtKB=F6WE05 F6WE05 UPF3A PTHR13112:SF2 UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN REGULATOR OF NONSENSE TRANSCRIPTS 3A mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;RNA binding#GO:0003723;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;positive regulation of protein metabolic process#GO:0051247;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of biosynthetic process#GO:0009891;positive regulation of translation#GO:0045727;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000010678.4|UniProtKB=F7C178 F7C178 CD5L PTHR48071:SF8 SRCR DOMAIN-CONTAINING PROTEIN CD5 ANTIGEN-LIKE regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;regulation of immune effector process#GO:0002697;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 MONDO|Ensembl=ENSMODG00000036382.1|UniProtKB=A0A5F8G4D1 A0A5F8G4D1 LOC100619937 PTHR47564:SF1 CYSTEINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 CYSTEINE-RICH TRANSMEMBRANE MODULE-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000011733.3|UniProtKB=F7FSS1 F7FSS1 PTHR16483:SF2 GASTROKINE 1 GASTROKINE-3 regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;biological regulation#GO:0065007;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000043951.1|UniProtKB=A0A5F8GHJ0 A0A5F8GHJ0 LOC100618408 PTHR26453:SF238 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10N1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040578.1|UniProtKB=A0A5F8GW36 A0A5F8GW36 SLC30A1 PTHR45820:SF1 FI23527P1 PROTON-COUPLED ZINC ANTIPORTER SLC30A1 molecular function regulator activity#GO:0098772;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;calcium channel regulator activity#GO:0005246;zinc ion transmembrane transporter activity#GO:0005385;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;monoatomic cation transmembrane transporter activity#GO:0008324;transporter regulator activity#GO:0141108;transition metal ion transmembrane transporter activity#GO:0046915 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;homeostatic process#GO:0042592;metal ion transport#GO:0030001;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;response to metal ion#GO:0010038;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;detoxification#GO:0098754;monoatomic cation transmembrane transport#GO:0098655;response to chemical#GO:0042221;cellular process#GO:0009987;detoxification of inorganic compound#GO:0061687;monoatomic ion homeostasis#GO:0050801;response to stress#GO:0006950 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000002756.4|UniProtKB=F6YHB4 F6YHB4 GLUD1 PTHR11606:SF13 GLUTAMATE DEHYDROGENASE GLUTAMATE DEHYDROGENASE 1, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 Glutamine glutamate conversion#P02745>Glutamate Dehydrogenase#P02967 MONDO|Ensembl=ENSMODG00000017913.4|UniProtKB=F7F2C8 F7F2C8 STRAP PTHR19877:SF13 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I SERINE-THREONINE KINASE RECEPTOR-ASSOCIATED PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;Sm-like protein family complex#GO:0120114;intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;SMN complex#GO:0032797 translation initiation factor#PC00224;translation factor#PC00223 MONDO|Ensembl=ENSMODG00000018866.4|UniProtKB=F7DAR8 F7DAR8 RFX5 PTHR12619:SF18 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000014883.4|UniProtKB=F7GGI7 F7GGI7 ATP6V0A1 PTHR11629:SF68 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A 1 monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;enzyme binding#GO:0019899;binding#GO:0005488;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078 cellular component organization#GO:0016043;intracellular monoatomic ion homeostasis#GO:0006873;cellular localization#GO:0051641;transmembrane transport#GO:0055085;cellular component disassembly#GO:0022411;process utilizing autophagic mechanism#GO:0061919;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;monoatomic ion homeostasis#GO:0050801;organelle organization#GO:0006996;cellular process#GO:0009987;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;monoatomic cation transmembrane transport#GO:0098655;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;vesicle-mediated transport in synapse#GO:0099003;synaptic vesicle maturation#GO:0016188;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;catabolic process#GO:0009056;homeostatic process#GO:0042592;protein-containing complex disassembly#GO:0032984;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;monoatomic cation transport#GO:0006812;localization#GO:0051179;developmental maturation#GO:0021700;macroautophagy#GO:0016236;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;autophagosome maturation#GO:0097352;synaptic vesicle cycle#GO:0099504;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;proton transmembrane transport#GO:1902600;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;membrane#GO:0016020;cell periphery#GO:0071944;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;proton-transporting two-sector ATPase complex#GO:0016469 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000016386.4|UniProtKB=F7E9G2 F7E9G2 PIK3CG PTHR10048:SF34 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;biosynthetic process#GO:0009058;cell migration#GO:0016477;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;phosphatidylinositol phosphate biosynthetic process#GO:0046854;intracellular signal transduction#GO:0035556;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 kinase#PC00137 p53 pathway feedback loops 2#P04398>PI3K#P04661;Axon guidance mediated by netrin#P00009>PI3K#P00363;Integrin signalling pathway#P00034>PI3K#P00936;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;Ras Pathway#P04393>PI3K#P04567;Apoptosis signaling pathway#P00006>PI3K#P00310;PDGF signaling pathway#P00047>PI3K#P01168;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;B cell activation#P00010>PI3K#P00391;FGF signaling pathway#P00021>PI3K#P00640;T cell activation#P00053>PI3K#P01322;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;VEGF signaling pathway#P00056>PI3K#P01413;Angiogenesis#P00005>PI3K#P00236;EGF receptor signaling pathway#P00018>PI3K#P00557 MONDO|Ensembl=ENSMODG00000003714.3|UniProtKB=F7EWM4 F7EWM4 SEL1L PTHR11102:SF70 SEL-1-LIKE PROTEIN PROTEIN SEL-1 HOMOLOG 1 response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000008113.3|UniProtKB=A0A5F8GYP6 A0A5F8GYP6 PTHR48619:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 276 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 276 MONDO|Ensembl=ENSMODG00000009359.4|UniProtKB=F7BTD7 F7BTD7 PTHR11375:SF1 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 regulation of apoptotic process#GO:0042981;nucleocytoplasmic transport#GO:0006913;transport#GO:0006810;intracellular transport#GO:0046907;nuclear transport#GO:0051169;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000008989.4|UniProtKB=F7BQF0 F7BQF0 LNX2 PTHR19964:SF33 MULTIPLE PDZ DOMAIN PROTEIN LIGAND OF NUMB PROTEIN X 2 ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 scaffold/adaptor protein#PC00226 Notch signaling pathway#P00045>LNXp80#P01111 MONDO|Ensembl=ENSMODG00000025598.3|UniProtKB=A0A5F8GHQ4 A0A5F8GHQ4 GTF2H2C PTHR12695:SF2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED transcription initiation at RNA polymerase II promoter#GO:0006367;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;RNA metabolic process#GO:0016070 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transcription factor TFIIH holo complex#GO:0005675;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;transcription factor TFIIH core complex#GO:0000439;transferase complex#GO:1990234 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000019311.4|UniProtKB=F6YAS4 F6YAS4 COPS4 PTHR10855:SF12 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4 COP9 SIGNALOSOME COMPLEX SUBUNIT 4 cell junction#GO:0030054;nuclear protein-containing complex#GO:0140513;secretory vesicle#GO:0099503;nucleus#GO:0005634;presynapse#GO:0098793;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transport vesicle#GO:0030133;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;COP9 signalosome#GO:0008180;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 protease#PC00190 MONDO|Ensembl=ENSMODG00000003791.3|UniProtKB=F7AA21 F7AA21 VSIG2 PTHR45046:SF1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 2 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 2 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000041020.1|UniProtKB=K7E0W3 K7E0W3 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000008070.4|UniProtKB=A0A5F8G1Q7 A0A5F8G1Q7 ADAMTS18 PTHR13723:SF167 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 18 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000009815.4|UniProtKB=F6SFX9 F6SFX9 IGKC PTHR23411:SF36 TAPASIN IMMUNOGLOBULIN KAPPA CONSTANT immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000025352.1|UniProtKB=F7E665 F7E665 KCNE2 PTHR15282:SF8 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 2 transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;binding#GO:0005488;gated channel activity#GO:0022836;potassium channel regulator activity#GO:0015459;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324;ion channel regulator activity#GO:0099106;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;potassium channel activity#GO:0005267;transmembrane transporter binding#GO:0044325;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;channel regulator activity#GO:0016247 cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239;monoatomic cation transmembrane transport#GO:0098655;cardiac muscle cell action potential involved in contraction#GO:0086002;regulation of membrane potential#GO:0042391;heart process#GO:0003015;muscle system process#GO:0003012;action potential#GO:0001508;regulation of biological process#GO:0050789;export from cell#GO:0140352;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;actin filament-based movement#GO:0030048;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;potassium ion transport#GO:0006813;transport#GO:0006810;muscle contraction#GO:0006936;regulation of system process#GO:0044057;system process#GO:0003008;heart contraction#GO:0060047;establishment of localization#GO:0051234;cardiac muscle cell contraction#GO:0086003;regulation of heart contraction#GO:0008016;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;actin-mediated cell contraction#GO:0070252;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;monoatomic cation transport#GO:0006812;localization#GO:0051179 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000051497.1|UniProtKB=K7E057 K7E057 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000049962.1|UniProtKB=A0A5F8GXX0 A0A5F8GXX0 MRM2 PTHR10920:SF18 RIBOSOMAL RNA METHYLTRANSFERASE RRNA METHYLTRANSFERASE 2, MITOCHONDRIAL transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;O-methyltransferase activity#GO:0008171;catalytic activity, acting on a rRNA#GO:0140102 cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;rRNA modification#GO:0000154;protein-containing complex assembly#GO:0065003;methylation#GO:0032259;RNA metabolic process#GO:0016070;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribosomal large subunit assembly#GO:0000027;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein-RNA complex assembly#GO:0022618;RNA methylation#GO:0001510;rRNA processing#GO:0006364;organelle assembly#GO:0070925 RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000016710.4|UniProtKB=F7CI17 F7CI17 ITIH2 PTHR10338:SF14 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H2 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000049165.1|UniProtKB=A0A5F8GTI1 A0A5F8GTI1 PTHR23262:SF248 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-6 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000007200.5|UniProtKB=A0A5F8GAK5 A0A5F8GAK5 TEP1 PTHR44791:SF1 TELOMERASE PROTEIN COMPONENT 1 TEP1 TELOMERASE PROTEIN COMPONENT 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA-directed DNA polymerase activity#GO:0003964;RNA binding#GO:0003723;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;telomerase activity#GO:0003720;DNA polymerase activity#GO:0034061 cellular process#GO:0009987;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;mitotic recombination#GO:0006312;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;telomere organization#GO:0032200;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000015338.3|UniProtKB=F6XER3 F6XER3 NHEJ1 PTHR32235:SF1 NON-HOMOLOGOUS END-JOINING FACTOR 1 NON-HOMOLOGOUS END-JOINING FACTOR 1 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;DNA repair complex#GO:1990391;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nonhomologous end joining complex#GO:0070419 MONDO|Ensembl=ENSMODG00000000244.4|UniProtKB=H9H5V0 H9H5V0 PTHR10838:SF22 SYNAPTOGYRIN SYNAPTOGYRIN-4 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;secretion#GO:0046903;exocytosis#GO:0006887;secretion by cell#GO:0032940;regulated exocytosis#GO:0045055;transport#GO:0006810;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular component organization#GO:0016043;synaptic vesicle membrane organization#GO:0048499;cellular process#GO:0009987 cell junction#GO:0030054;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;presynapse#GO:0098793;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle#GO:0008021 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000015770.3|UniProtKB=F6ZS89 F6ZS89 GMPS PTHR11922:SF6 GMP SYNTHASE-RELATED GMP SYNTHASE [GLUTAMINE-HYDROLYZING] ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ligase#PC00142 De novo purine biosynthesis#P02738>GMP synthase#P02899 MONDO|Ensembl=ENSMODG00000043247.1|UniProtKB=A0A5F8HL83 A0A5F8HL83 PTHR41694:SF8 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 11 POL PROTEIN-LIKE RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003176.3|UniProtKB=F6VY82 F6VY82 PTGER3 PTHR11866:SF10 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological quality#GO:0065008;regulation of secretion#GO:0051046;cell communication#GO:0007154;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;signaling#GO:0023052;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;muscle system process#GO:0003012;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;defense response#GO:0006952;regulation of localization#GO:0032879;system process#GO:0003008;regulation of transport#GO:0051049;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;muscle contraction#GO:0006936;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of system process#GO:0044057;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836;PI3 kinase pathway#P00048>GPCR#P01204 MONDO|Ensembl=ENSMODG00000038952.1|UniProtKB=A0A5F8GJI2 A0A5F8GJI2 PTHR24237:SF40 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 141B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000010703.4|UniProtKB=A0A5F8G9X7 A0A5F8G9X7 PSMD1 PTHR10943:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;endopeptidase complex#GO:1905369;cytoplasm#GO:0005737;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;proteasome complex#GO:0000502 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000018730.3|UniProtKB=H9H775 H9H775 TMEM184B PTHR23423:SF28 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184B transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000029793.2|UniProtKB=K7DZQ2 K7DZQ2 C6H4orf50 PTHR36866:SF1 CHROMOSOME 4 OPEN READING FRAME 50 GENE 1043-RELATED MONDO|Ensembl=ENSMODG00000050533.1|UniProtKB=A0A5F8GEQ3 A0A5F8GEQ3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000018086.4|UniProtKB=F7FTG8 F7FTG8 PLCXD2 PTHR13593:SF32 FAMILY NOT NAMED PI-PLC X DOMAIN-CONTAINING PROTEIN 2 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 MONDO|Ensembl=ENSMODG00000008769.3|UniProtKB=F6RGQ4 F6RGQ4 PCBD1 PTHR12599:SF13 PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 dehydratase#PC00091;lyase#PC00144 MONDO|Ensembl=ENSMODG00000014684.3|UniProtKB=F7DNN3 F7DNN3 TSPAN33 PTHR19282:SF154 TETRASPANIN TETRASPANIN-33 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000041159.1|UniProtKB=A0A5F8GB60 A0A5F8GB60 PRF1 PTHR46096:SF3 PERFORIN-1 PERFORIN-1 channel activity#GO:0015267;wide pore channel activity#GO:0022829;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 response to other organism#GO:0051707;adaptive immune response#GO:0002250;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;immune response#GO:0006955;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;cell-cell recognition#GO:0009988;immune effector process#GO:0002252;cell killing#GO:0001906;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;defense response to virus#GO:0051607;leukocyte activation#GO:0045321;leukocyte mediated cytotoxicity#GO:0001909;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;response to virus#GO:0009615;T cell mediated immunity#GO:0002456;cell recognition#GO:0008037;cell activation#GO:0001775;immune system process#GO:0002376 membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000047058.1|UniProtKB=A0A5F8HJZ0 A0A5F8HJZ0 VN2R589 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000049911.1|UniProtKB=A0A5F8G8T6 A0A5F8G8T6 PIGH PTHR15231:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000002275.4|UniProtKB=F7CVV8 F7CVV8 CMSS1 PTHR24030:SF0 PROTEIN CMSS1 PROTEIN CMSS1 DNA replication#GO:0006260;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000017687.4|UniProtKB=F7G5M4 F7G5M4 NCOA7 PTHR23354:SF68 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED NUCLEAR RECEPTOR COACTIVATOR 7 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;response to oxidative stress#GO:0006979 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000000863.4|UniProtKB=A0A5F8HC12 A0A5F8HC12 KLF12 PTHR23235:SF56 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 12 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016093.2|UniProtKB=F7FYT8 F7FYT8 RNF151 PTHR15315:SF64 RING FINGER PROTEIN 41, 151 RING FINGER PROTEIN 151 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum tubular network#GO:0071782;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000018118.4|UniProtKB=F7F1Z0 F7F1Z0 CCDC80 PTHR46792:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 80 COILED-COIL DOMAIN-CONTAINING PROTEIN 80 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cell adhesion#GO:0045785;cellular process#GO:0009987;positive regulation of cell-substrate adhesion#GO:0010811;cellular component organization#GO:0016043;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000039467.1|UniProtKB=A0A5F8H3K9 A0A5F8H3K9 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000027594.2|UniProtKB=K7DYQ9 K7DYQ9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000017368.3|UniProtKB=F6VYT4 F6VYT4 S100A1 PTHR11639:SF160 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A1 binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;sarcoplasmic reticulum#GO:0016529;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;sarcoplasm#GO:0016528 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000005509.3|UniProtKB=F7G5W4 F7G5W4 PTHR11461:SF204 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B6 enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000040180.1|UniProtKB=A0A5F8H591 A0A5F8H591 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000023859.3|UniProtKB=F6XKH6 F6XKH6 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000012350.2|UniProtKB=F7E1W8 F7E1W8 PTHR11500:SF0 BETA CASEIN BETA-CASEIN endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;regulation of body fluid levels#GO:0050878;developmental process#GO:0032502;transport#GO:0006810;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;localization#GO:0051179;animal organ development#GO:0048513;anatomical structure development#GO:0048856;secretion#GO:0046903;establishment of localization#GO:0051234 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 storage protein#PC00210 MONDO|Ensembl=ENSMODG00000012905.4|UniProtKB=F7GKQ5 F7GKQ5 PPP2R3C PTHR12085:SF7 SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT GAMMA SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT GAMMA regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of lymphocyte activation#GO:0051249;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;microtubule cytoskeleton organization#GO:0000226;cortical cytoskeleton organization#GO:0030865;regulation of multicellular organismal process#GO:0051239;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of B cell activation#GO:0050864;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000045492.1|UniProtKB=A0A5F8GKP9 A0A5F8GKP9 PTHR11362:SF82 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4 protease inhibitor#PC00191 FGF signaling pathway#P00021>RKIP#P00630;EGF receptor signaling pathway#P00018>RKIP#P00548 MONDO|Ensembl=ENSMODG00000023774.1|UniProtKB=F6SDG9 F6SDG9 SLC35A4 PTHR10231:SF109 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-SUGAR TRANSPORTER PROTEIN SLC35A4-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227 MONDO|Ensembl=ENSMODG00000025791.3|UniProtKB=F7FSN3 F7FSN3 LOC100032993 PTHR11905:SF108 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 2 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;reproductive structure development#GO:0048608;fertilization#GO:0009566;cell adhesion#GO:0007155;sexual reproduction#GO:0019953;cell recognition#GO:0008037;proteolysis#GO:0006508;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;reproductive system development#GO:0061458;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;binding of sperm to zona pellucida#GO:0007339;male gonad development#GO:0008584;cellular process#GO:0009987;sex differentiation#GO:0007548;single fertilization#GO:0007338;gonad development#GO:0008406;multicellular organismal process#GO:0032501;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;male sex differentiation#GO:0046661;development of primary male sexual characteristics#GO:0046546;metabolic process#GO:0008152;sperm-egg recognition#GO:0035036;cell-cell recognition#GO:0009988;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;animal organ development#GO:0048513 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000024443.3|UniProtKB=F7CZK5 F7CZK5 HOMEZ PTHR15467:SF7 ZINC-FINGERS AND HOMEOBOXES RELATED HOMEOBOX AND LEUCINE ZIPPER PROTEIN HOMEZ transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000017634.4|UniProtKB=F6ZSA6 F6ZSA6 AFG2B PTHR23077:SF117 AAA-FAMILY ATPASE ATPASE FAMILY GENE 2 PROTEIN HOMOLOG B ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000018169.4|UniProtKB=A0A5F8H601 A0A5F8H601 CCDC191 PTHR22028:SF5 SFI1 SPINDLE BODY DOMAIN-CONTAINING PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 191 protein binding#GO:0005515;enzyme binding#GO:0019899;phosphatase binding#GO:0019902;binding#GO:0005488 MONDO|Ensembl=ENSMODG00000030802.2|UniProtKB=A0A5F8H6G0 A0A5F8H6G0 PTHR35825:SF2 CASEIN KINASE II SUBUNIT ALPHA PRIME-INTERACTING PROTEIN CASEIN KINASE II SUBUNIT ALPHA'-INTERACTING PROTEIN MONDO|Ensembl=ENSMODG00000003699.4|UniProtKB=F7FAE9 F7FAE9 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023081.1|UniProtKB=F7FR58 F7FR58 LOC103096066 PTHR48001:SF43 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1N1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000292.4|UniProtKB=A0A5F8G8Q3 A0A5F8G8Q3 DDAH1 PTHR12737:SF17 DIMETHYLARGININE DIMETHYLAMINOHYDROLASE N(G),N(G)-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;regulation of biological process#GO:0050789;small molecule metabolic process#GO:0044281;regulation of cellular process#GO:0050794;oxoacid metabolic process#GO:0043436;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000013874.2|UniProtKB=F6W9A4 F6W9A4 SOWAHA PTHR14491:SF2 SOSONDOWAH, ISOFORM G ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHA Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000040695.1|UniProtKB=A0A5F8GRH4 A0A5F8GRH4 OLFM2 PTHR23192:SF27 OLFACTOMEDIN-RELATED NOELIN-2 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000002855.4|UniProtKB=A0A5F8G9L2 A0A5F8G9L2 DCAF6 PTHR15574:SF39 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 6 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000019183.4|UniProtKB=F7AWK6 F7AWK6 PSMD11 PTHR10678:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 proteasome complex#GO:0000502;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 MONDO|Ensembl=ENSMODG00000014053.4|UniProtKB=F6QIU1 F6QIU1 CSMD1 PTHR45656:SF3 PROTEIN CBR-CLEC-78 CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 1 tube development#GO:0035295;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;morphogenesis of a branching structure#GO:0001763;morphogenesis of an epithelium#GO:0002009;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;reproductive process#GO:0022414;animal organ morphogenesis#GO:0009887;tube morphogenesis#GO:0035239;multi-multicellular organism process#GO:0044706;anatomical structure morphogenesis#GO:0009653;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;animal gross anatomical part developmental process#GO:0160108 MONDO|Ensembl=ENSMODG00000014489.4|UniProtKB=F7FKT7 F7FKT7 SIK2 PTHR24343:SF154 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE SIK2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000005532.4|UniProtKB=F7FUQ9 F7FUQ9 TUBGCP6 PTHR19302:SF70 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 6 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;spindle assembly#GO:0051225;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;cytoplasmic microtubule organization#GO:0031122;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694 microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000012392.4|UniProtKB=A0A5F8GSE0 A0A5F8GSE0 ERC2 PTHR18861:SF3 ELKS/RAB6-INTERACTING/CAST PROTEIN ERC PROTEIN 2 structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 presynaptic active zone#GO:0048786;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cell periphery#GO:0071944;presynapse#GO:0098793;cell cortex#GO:0005938 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000016490.4|UniProtKB=F7EQE3 F7EQE3 CTCFL PTHR24406:SF36 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED TRANSCRIPTIONAL REPRESSOR CTCFL zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016277.2|UniProtKB=F7BGN4 F7BGN4 INTS15 PTHR14540:SF2 INTEGRATOR COMPLEX SUBUNIT 15 INTEGRATOR COMPLEX SUBUNIT 15 intracellular organelle#GO:0043229;integrator complex#GO:0032039;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000038477.1|UniProtKB=A0A5F8H3B9 A0A5F8H3B9 LOC100031974 PTHR24339:SF66 HOMEOBOX PROTEIN EMX-RELATED EMPTY SPIRACLES HOMEOBOX 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;head development#GO:0060322;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;neuron differentiation#GO:0030182;developmental process#GO:0032502;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000004350.4|UniProtKB=A0A5F8HA77 A0A5F8HA77 BANP PTHR16243:SF2 BTG3-ASSOCIATED NUCLEAR PROTEIN BANP PROTEIN BANP MONDO|Ensembl=ENSMODG00000017579.4|UniProtKB=F7B5W0 F7B5W0 AP4S1 PTHR11753:SF4 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-4 COMPLEX SUBUNIT SIGMA-1 vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000004508.3|UniProtKB=F6V9A8 F6V9A8 RAB3GAP2 PTHR12472:SF1 RAB3-GAP REGULATORY DOMAIN RAB3 GTPASE-ACTIVATING PROTEIN NON-CATALYTIC SUBUNIT binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function regulator activity#GO:0098772 cell-cell signaling#GO:0007267;establishment of protein localization to endoplasmic reticulum#GO:0072599;biological regulation#GO:0065007;macroautophagy#GO:0016236;establishment of protein localization to membrane#GO:0090150;synaptic signaling#GO:0099536;establishment of protein localization#GO:0045184;autophagy#GO:0006914;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;metabolic process#GO:0008152;catabolic process#GO:0009056;signaling#GO:0023052;regulation of biological process#GO:0050789;cell communication#GO:0007154;localization#GO:0051179;cellular localization#GO:0051641;process utilizing autophagic mechanism#GO:0061919;localization within membrane#GO:0051668 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;synaptic membrane#GO:0097060;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020 G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000048909.1|UniProtKB=F6Q1S7 F6Q1S7 LOC100617735 PTHR26450:SF69 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56B1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000044219.1|UniProtKB=F7DDV2 F7DDV2 LOC100024707 PTHR26450:SF151 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52B2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012459.4|UniProtKB=F6PHT7 F6PHT7 PTHR15466:SF2 V-SET AND IMMUNOGLOBULIN DOMAIN CONTAINING 4 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 4 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000001300.4|UniProtKB=A0A5F8GGM9 A0A5F8GGM9 ELAVL4 PTHR10352:SF9 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 4 regulation of mRNA metabolic process#GO:1903311;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;nervous system development#GO:0007399;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;RNA stabilization#GO:0043489;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of RNA catabolic process#GO:1902369;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of catabolic process#GO:0009895;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;perikaryon#GO:0043204;intracellular anatomical structure#GO:0005622;cell body#GO:0044297;nucleus#GO:0005634;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 MONDO|Ensembl=ENSMODG00000016359.4|UniProtKB=F7A5H3 F7A5H3 LOC100617027 PTHR13468:SF24 DEK PROTEIN PROTEIN DEK histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular response to stress#GO:0080135;regulation of double-strand break repair#GO:2000779;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000017691.4|UniProtKB=F7G5B7 F7G5B7 BCAT1 PTHR11825:SF70 SUBGROUP IIII AMINOTRANSFERASE BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE, CYTOSOLIC transferase activity#GO:0016740;catalytic activity#GO:0003824;transaminase activity#GO:0008483 small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 transferase#PC00220;transaminase#PC00216 Isoleucine biosynthesis#P02748>Branched chain amino acid aminotransferase#P02994;Valine biosynthesis#P02785>Branched chain amino acid aminotransferase#P03215;Alanine biosynthesis#P02724>Branched chain amino acid aminotransferase#P02815;Leucine biosynthesis#P02749>Branched chain amino acid aminotransferase#P03000 MONDO|Ensembl=ENSMODG00000008669.4|UniProtKB=F6PFZ6 F6PFZ6 SRSF7 PTHR23147:SF288 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 7 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear speck#GO:0016607;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000024944.1|UniProtKB=F6VCP9 F6VCP9 KCTD4 PTHR14499:SF9 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000001191.3|UniProtKB=F7GHB2 F7GHB2 RGS4 PTHR10845:SF184 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 4 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of biological process#GO:0050789;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057 cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 MONDO|Ensembl=ENSMODG00000012308.4|UniProtKB=F7EIZ0 F7EIZ0 CCDC62 PTHR34491:SF134 A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 62 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000015223.3|UniProtKB=A0A5F8G1P0 A0A5F8G1P0 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000043029.1|UniProtKB=A0A5F8HHV5 A0A5F8HHV5 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002954.4|UniProtKB=A0A5F8GSJ8 A0A5F8GSJ8 SYNPR PTHR10306:SF16 SYNAPTOPHYSIN SYNAPTOPORIN cell junction#GO:0030054;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;presynapse#GO:0098793;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000041685.1|UniProtKB=A0A5F8H7L0 A0A5F8H7L0 LOC100014093 PTHR12010:SF2 40S RIBOSOMAL PROTEIN S29 SMALL RIBOSOMAL SUBUNIT PROTEIN US14 transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872;zinc ion binding#GO:0008270;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000009065.4|UniProtKB=F7FR09 F7FR09 PAN3 PTHR12272:SF11 DEADENYLATION COMPLEX SUBUNIT PAN3 PAN2-PAN3 DEADENYLATION COMPLEX SUBUNIT PAN3 nucleic acid binding#GO:0003676;binding#GO:0005488;poly(A) binding#GO:0008143;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401 catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 exoribonuclease#PC00099 MONDO|Ensembl=ENSMODG00000045692.1|UniProtKB=A0A5F8GE72 A0A5F8GE72 ANKRD54 PTHR24197:SF51 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 61 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 54 enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000005403.6|UniProtKB=F6S4Y4 F6S4Y4 NCAPD3 PTHR14222:SF1 CONDENSIN CONDENSIN-2 COMPLEX SUBUNIT D3 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;organelle fission#GO:0048285;sexual reproduction#GO:0019953;nuclear division#GO:0000280 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;condensin complex#GO:0000796 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000011774.4|UniProtKB=F7CVZ2 F7CVZ2 ASB16 PTHR24188:SF29 ANKYRIN REPEAT PROTEIN GH09064P MONDO|Ensembl=ENSMODG00000004132.1|UniProtKB=F6UVK9 F6UVK9 UQCR11 PTHR15420:SF2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 6.4 KD PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 10 mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000043271.1|UniProtKB=A0A5F8G632 A0A5F8G632 LOC100015365 PTHR23419:SF2 DIVALENT CATION TOLERANCE CUTA-RELATED CUTA DIVALENT CATION TOLERANCE HOMOLOG-LIKE transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;copper ion binding#GO:0005507;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000024701.2|UniProtKB=F7B210 F7B210 PTHR20937:SF6 IP14615P MESODERM POSTERIOR PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;gastrulation#GO:0007369;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;formation of primary germ layer#GO:0001704;heart development#GO:0007507;embryo development#GO:0009790;embryonic pattern specification#GO:0009880;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;mesoderm development#GO:0007498;anterior/posterior axis specification#GO:0009948;anatomical structure formation involved in morphogenesis#GO:0048646;anterior/posterior pattern specification#GO:0009952;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;heart morphogenesis#GO:0003007;mesoderm morphogenesis#GO:0048332;tissue morphogenesis#GO:0048729;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;mesoderm formation#GO:0001707;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;regionalization#GO:0003002;multicellular organismal process#GO:0032501;tissue development#GO:0009888;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000018056.4|UniProtKB=F7G4G9 F7G4G9 PTHR46861:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A death receptor activity#GO:0005035;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089;tumor necrosis factor binding#GO:0043120;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955 response to stress#GO:0006950;inflammatory response#GO:0006954;response to stimulus#GO:0050896;defense response#GO:0006952 membrane raft#GO:0045121;membrane#GO:0016020;signaling receptor complex#GO:0043235;membrane microdomain#GO:0098857;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Apoptosis signaling pathway#P00006>TNFR1#P00288 MONDO|Ensembl=ENSMODG00000048947.1|UniProtKB=A0A5F8G1N4 A0A5F8G1N4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000027502.2|UniProtKB=K7DZN5 K7DZN5 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000027968.2|UniProtKB=K7DYZ2 K7DYZ2 PTHR33166:SF1 GAG_P30 DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000004302.1|UniProtKB=F6SX69 F6SX69 LAMTOR4 PTHR33967:SF1 RAGULATOR COMPLEX PROTEIN LAMTOR4 RAGULATOR COMPLEX PROTEIN LAMTOR4 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to acid chemical#GO:0001101;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;bounding membrane of organelle#GO:0098588 MONDO|Ensembl=ENSMODG00000001275.3|UniProtKB=F7CIW1 F7CIW1 PTHR10114:SF36 60S RIBOSOMAL PROTEIN L36 60S RIBOSOMAL PROTEIN L36 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000004308.4|UniProtKB=A0A5F8G5L6 A0A5F8G5L6 BRWD3 PTHR16266:SF25 WD REPEAT DOMAIN 9 BROMODOMAIN AND WD REPEAT-CONTAINING PROTEIN 3 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000042491.1|UniProtKB=A0A5F8GIX2 A0A5F8GIX2 PTHR12621:SF12 CYSTEINE AND HISTIDINE-RICH DOMAIN CHORD -CONTAINING PROTEIN CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;zinc ion binding#GO:0008270;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoskeleton organization#GO:0007010;cellular process#GO:0009987;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004957.4|UniProtKB=F7FLA2 F7FLA2 WDSUB1 PTHR46573:SF1 WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1 WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000000580.4|UniProtKB=F6WP06 F6WP06 TJP3 PTHR13865:SF11 TIGHT JUNCTION PROTEIN TIGHT JUNCTION PROTEIN ZO-3 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 circulatory system process#GO:0003013;animal gross anatomical part developmental process#GO:0160108;protein localization to cell junction#GO:1902414;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;localization#GO:0051179;regulation of biological quality#GO:0065008;tissue homeostasis#GO:0001894;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cell differentiation#GO:0030154;cell development#GO:0048468;homeostatic process#GO:0042592;cell-cell junction organization#GO:0045216;endothelial cell differentiation#GO:0045446;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organismal-level homeostasis#GO:0048871;system process#GO:0003008;intracellular protein localization#GO:0008104;cell-cell adhesion#GO:0098609;macromolecule localization#GO:0033036;cellular process#GO:0009987;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;blood circulation#GO:0008015;biological regulation#GO:0065007 apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923 cell junction protein#PC00070;tight junction#PC00214 MONDO|Ensembl=ENSMODG00000008095.2|UniProtKB=F7GFV0 F7GFV0 RAB7A PTHR47981:SF13 RAB FAMILY RAS-RELATED PROTEIN RAB-7A molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cellular component organization#GO:0016043;vesicle fusion#GO:0006906;endocytosis#GO:0006897;organelle assembly#GO:0070925;lysosomal transport#GO:0007041;endosome to lysosome transport#GO:0008333;vacuole organization#GO:0007033;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;lysosome organization#GO:0007040;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membrane fusion#GO:0061025;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;lytic vacuole organization#GO:0080171;transport#GO:0006810;vacuolar transport#GO:0007034;phagocytosis#GO:0006909;intracellular transport#GO:0046907;phagolysosome assembly#GO:0001845;vesicle organization#GO:0016050;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vacuole#GO:0005773;cytoplasm#GO:0005737;phagocytic vesicle#GO:0045335;endomembrane system#GO:0012505;late endosome#GO:0005770;lytic vacuole#GO:0000323 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000007861.4|UniProtKB=F7EBG3 F7EBG3 PHEX PTHR11733:SF133 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED PHOSPHATE-REGULATING NEUTRAL ENDOPEPTIDASE PHEX peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000002544.4|UniProtKB=A0A5F8G9K5 A0A5F8G9K5 PARPBP PTHR32121:SF0 PCNA-INTERACTING PARTNER PCNA-INTERACTING PARTNER negative regulation of double-strand break repair via homologous recombination#GO:2000042;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of DNA recombination#GO:0000018;regulation of cellular response to stress#GO:0080135;regulation of double-strand break repair#GO:2000779;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;negative regulation of biological process#GO:0048519;negative regulation of DNA recombination#GO:0045910;negative regulation of metabolic process#GO:0009892;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000038072.1|UniProtKB=A0A5F8G5K0 A0A5F8G5K0 PTHR10867:SF32 NNMT/PNMT/TEMT FAMILY MEMBER MGC107884 PROTEIN N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 MONDO|Ensembl=ENSMODG00000048152.1|UniProtKB=A0A5F8HDM9 A0A5F8HDM9 ERMN PTHR47137:SF1 ERMIN ERMIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of cellular component organization#GO:0051128;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;regulation of biological quality#GO:0065008;morphogenesis of a branching structure#GO:0001763;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of cell projection organization#GO:0031344;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;actin filament organization#GO:0007015 actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;cell body#GO:0044297;actin-based cell projection#GO:0098858;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;filopodium#GO:0030175;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;main axon#GO:0044304;cell periphery#GO:0071944;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;myelin sheath#GO:0043209;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000025551.3|UniProtKB=F6UIM9 F6UIM9 PTHR14330:SF2 A-KINASE-INTERACTING PROTEIN 1 A-KINASE-INTERACTING PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000006124.2|UniProtKB=F7EI03 F7EI03 PTHR10408:SF6 STEROL O-ACYLTRANSFERASE STEROL O-ACYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;steroid binding#GO:0005496;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;alcohol binding#GO:0043178;heterocyclic compound binding#GO:1901363;acyltransferase activity#GO:0016746;nucleoside phosphate binding#GO:1901265;sterol binding#GO:0032934;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;cholesterol binding#GO:0015485;lipid binding#GO:0008289 establishment of localization#GO:0051234;sterol transport#GO:0015918;sterol metabolic process#GO:0016125;transport#GO:0006810;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;steroid metabolic process#GO:0008202;lipid transport#GO:0006869;cellular process#GO:0009987;cholesterol efflux#GO:0033344;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;lipid localization#GO:0010876;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 acyltransferase#PC00042;transferase#PC00220 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 MONDO|Ensembl=ENSMODG00000044810.1|UniProtKB=A0A5F8G3L4 A0A5F8G3L4 RAB33B PTHR47978:SF26 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-33B hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076 cellular component assembly#GO:0022607;biological regulation#GO:0065007;macroautophagy#GO:0016236;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component organization or biogenesis#GO:0071840;regulation of localization#GO:0032879;regulation of transport#GO:0051049;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;cellular component organization#GO:0016043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of secretion#GO:0051046;vacuole organization#GO:0007033;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;process utilizing autophagic mechanism#GO:0061919;organelle assembly#GO:0070925 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endosome#GO:0005768 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000011717.4|UniProtKB=A0A5F8H325 A0A5F8H325 POC1A PTHR44019:SF2 WD REPEAT-CONTAINING PROTEIN 55 POC1 CENTRIOLAR PROTEIN HOMOLOG A plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;centriole#GO:0005814;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000011102.4|UniProtKB=A0A5F8HDR5 A0A5F8HDR5 WAPL PTHR22100:SF13 WINGS APART-LIKE PROTEIN HOMOLOG WINGS APART-LIKE PROTEIN HOMOLOG MONDO|Ensembl=ENSMODG00000015931.4|UniProtKB=F6ZQK9 F6ZQK9 KLHL30 PTHR24412:SF398 KELCH PROTEIN KELCH-LIKE PROTEIN 30 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000024819.2|UniProtKB=A0A5F8HH42 A0A5F8HH42 PTHR13293:SF9 AKIRIN-RELATED AKIRIN-1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of response to stress#GO:0080134;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of innate immune response#GO:0045089;cell migration#GO:0016477;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of granulocyte chemotaxis#GO:0071622;positive regulation of chemotaxis#GO:0050921;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of cell motility#GO:2000145;regulation of cell projection assembly#GO:0060491;regulation of leukocyte migration#GO:0002685;regulation of response to biotic stimulus#GO:0002831;regulation of developmental process#GO:0050793;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of response to external stimulus#GO:0032103;positive regulation of cellular component organization#GO:0051130;positive regulation of metabolic process#GO:0009893;positive regulation of cell motility#GO:2000147;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;positive regulation of developmental process#GO:0051094;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of cell migration#GO:0030334;regulation of biosynthetic process#GO:0009889;developmental growth#GO:0048589;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of locomotion#GO:0040017;negative regulation of cell population proliferation#GO:0008285;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of defense response#GO:0031347;positive regulation of cell projection organization#GO:0031346;regulation of immune response#GO:0050776;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;positive regulation of cell differentiation#GO:0045597;growth#GO:0040007;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular component biogenesis#GO:0044089;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;regeneration#GO:0031099;animal gross anatomical part developmental process#GO:0160108;tissue regeneration#GO:0042246;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of chemotaxis#GO:0050920;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000020336.3|UniProtKB=A0A5F8GV45 A0A5F8GV45 PTHR24229:SF8 NEUROPEPTIDES RECEPTOR PROSTAGLANDIN D2 RECEPTOR 2 binding#GO:0005488;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000018264.2|UniProtKB=F6QJ55 F6QJ55 LOC100030998 PTHR14819:SF5 GTP-BINDING INTERFERON-INDUCED VERY LARGE GTPASE 1 MONDO|Ensembl=ENSMODG00000004243.4|UniProtKB=F6UBD7 F6UBD7 TMUB1 PTHR14557:SF3 PROTEIN C7ORF21 TRANSMEMBRANE AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN 1 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896 MONDO|Ensembl=ENSMODG00000009442.4|UniProtKB=A0A5F8G2Y7 A0A5F8G2Y7 EDC3 PTHR13612:SF0 ENHANCER OF MRNA-DECAPPING PROTEIN 3 ENHANCER OF MRNA-DECAPPING PROTEIN 3 molecular condensate scaffold activity#GO:0140693;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;mRNA binding#GO:0003729;molecular adaptor activity#GO:0060090 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;P-body assembly#GO:0033962;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;RNA decapping#GO:0110154;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;organelle organization#GO:0006996;mRNA catabolic process#GO:0006402;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;cellular component assembly#GO:0022607;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000023036.1|UniProtKB=F6RF27 F6RF27 LRRTM1 PTHR24373:SF290 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT TRANSMEMBRANE NEURONAL PROTEIN 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009301.4|UniProtKB=F6TXS8 F6TXS8 ANXA6 PTHR10502:SF19 ANNEXIN ANNEXIN A6 lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;ion binding#GO:0043167;phospholipid binding#GO:0005543;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801;signal transduction#GO:0007165;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;response to stimulus#GO:0050896;signaling#GO:0023052;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;establishment of localization#GO:0051234;apoptotic signaling pathway#GO:0097190;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;regulation of cellular process#GO:0050794;mitochondrial calcium ion homeostasis#GO:0051560;metal ion transport#GO:0030001;homeostatic process#GO:0042592;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000024459.2|UniProtKB=F6YIW2 F6YIW2 PTHR19367:SF51 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 16 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000045485.1|UniProtKB=A0A5F8GIG5 A0A5F8GIG5 GDF2 PTHR11848:SF157 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 2 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;positive regulation of epithelial cell proliferation#GO:0050679;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000024820.3|UniProtKB=F7AB51 F7AB51 GRXCR1 PTHR46990:SF1 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 1 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 1 cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;inner ear receptor cell stereocilium organization#GO:0060122;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;ear development#GO:0043583;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;inner ear development#GO:0048839;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;sensory organ development#GO:0007423;neuron differentiation#GO:0030182;developmental process#GO:0032502 actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular organelle#GO:0043229;cilium#GO:0005929;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;neuron projection#GO:0043005;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;stereocilium#GO:0032420;membraneless organelle#GO:0043228 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000003131.4|UniProtKB=F6WUY4 F6WUY4 PGM5 PTHR22573:SF27 PHOSPHOHEXOMUTASE FAMILY MEMBER PHOSPHOGLUCOMUTASE-LIKE PROTEIN 5 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868 developmental process#GO:0032502;cellular developmental process#GO:0048869;tissue development#GO:0009888;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;muscle tissue development#GO:0060537;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;striated muscle tissue development#GO:0014706;metabolic process#GO:0008152;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;anatomical structure morphogenesis#GO:0009653;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154 cytoplasm#GO:0005737;cell-substrate junction#GO:0030055;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;adherens junction#GO:0005912;sarcolemma#GO:0042383;cell junction#GO:0030054 mutase#PC00160;metabolite interconversion enzyme#PC00262;isomerase#PC00135 MONDO|Ensembl=ENSMODG00000024473.1|UniProtKB=F6YHH4 F6YHH4 FJX1 PTHR13147:SF5 FOUR-JOINTED BOX PROTEIN 1 FOUR-JOINTED BOX PROTEIN 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;regulation of biological process#GO:0050789 MONDO|Ensembl=ENSMODG00000013712.4|UniProtKB=F6Y9E1 F6Y9E1 PTHR19237:SF21 NUCLEOBINDIN NUCLEOBINDIN-1 calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000048808.1|UniProtKB=A0A5F8H5P6 A0A5F8H5P6 LOC100021783 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000046336.1|UniProtKB=A0A5F8GUQ1 A0A5F8GUQ1 LCLAT1 PTHR10983:SF81 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED LYSOCARDIOLIPIN ACYLTRANSFERASE 1 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 acyltransferase#PC00042;transferase#PC00220 MONDO|Ensembl=ENSMODG00000002440.5|UniProtKB=F7DZU5 F7DZU5 MARCHF6 PTHR13145:SF0 SSM4 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE MARCHF6 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000012246.4|UniProtKB=A0A5F8GZ21 A0A5F8GZ21 CEP89 PTHR36170:SF1 CENTROSOMAL PROTEIN OF 89 KDA CENTROSOMAL PROTEIN OF 89 KDA organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;mitochondrion organization#GO:0007005 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary transition fiber#GO:0097539;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000021058.4|UniProtKB=A0A5F8H3R0 A0A5F8H3R0 ITSN1 PTHR11216:SF68 EH DOMAIN INTERSECTIN-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 synaptic vesicle endocytosis#GO:0048488;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;intracellular transport#GO:0046907;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;establishment of localization#GO:0051234;endosomal transport#GO:0016197;receptor-mediated endocytosis#GO:0006898 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000043441.1|UniProtKB=A0A5F8HJ24 A0A5F8HJ24 LOC100010109 PTHR24264:SF15 TRYPSIN-RELATED TRYPSIN catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000009033.4|UniProtKB=F7B2I8 F7B2I8 EGFR PTHR24416:SF91 TYROSINE-PROTEIN KINASE RECEPTOR EPIDERMAL GROWTH FACTOR RECEPTOR transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;hormone binding#GO:0042562;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740;protein kinase activity#GO:0004672;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 nervous system development#GO:0007399;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;multicellular organismal process#GO:0032501;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;ERBB signaling pathway#GO:0038127;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;negative regulation of cellular process#GO:0048523;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of epithelial cell proliferation#GO:0050679;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>EGFR#P00466;EGF receptor signaling pathway#P00018>EGFR#P00542;Gonadotropin-releasing hormone receptor pathway#P06664>EGFR#P06843 MONDO|Ensembl=ENSMODG00000001722.2|UniProtKB=H9H5X9 H9H5X9 TMT1B PTHR42912:SF93 METHYLTRANSFERASE THIOL S-METHYLTRANSFERASE TMT1A transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 transferase#PC00220;methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000041109.1|UniProtKB=A0A5F8GSP1 A0A5F8GSP1 CCER1 PTHR37337:SF1 COILED-COIL DOMAIN-CONTAINING GLUTAMATE-RICH PROTEIN 1 COILED-COIL DOMAIN-CONTAINING GLUTAMATE-RICH PROTEIN 1 MONDO|Ensembl=ENSMODG00000009142.4|UniProtKB=A0A5F8HDB2 A0A5F8HDB2 LYN PTHR24418:SF42 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE LYN transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096;non-membrane spanning protein tyrosine kinase activity#GO:0004715;binding#GO:0005488;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515 regulation of B cell receptor signaling pathway#GO:0050855;regulation of cell communication#GO:0010646;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;system development#GO:0048731;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of immune response#GO:0050776;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;immune response-regulating cell surface receptor signaling pathway#GO:0002768;hemopoiesis#GO:0030097;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of immune response#GO:0050778;developmental process#GO:0032502;DNA damage response#GO:0006974;regulation of response to stimulus#GO:0048583;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;mononuclear cell differentiation#GO:1903131;cellular component organization#GO:0016043;leukocyte differentiation#GO:0002521;neuron development#GO:0048666;immune system development#GO:0002520;cellular response to stress#GO:0033554;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;cellular component organization or biogenesis#GO:0071840;immune response-activating signaling pathway#GO:0002757;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 B cell activation#P00010>Lyn#P00374;CCKR signaling map#P06959>LYN#P07141;Parkinson disease#P00049>Src kinase#P01230;Cadherin signaling pathway#P00012>Yes#P00476 MONDO|Ensembl=ENSMODG00000012412.5|UniProtKB=F6PME3 F6PME3 AR PTHR48092:SF13 KNIRPS-RELATED PROTEIN-RELATED ANDROGEN RECEPTOR nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;gonad development#GO:0008406;nuclear receptor-mediated signaling pathway#GO:0141193;male gamete generation#GO:0048232;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;spermatogenesis#GO:0007283;developmental process#GO:0032502;male sex differentiation#GO:0046661;development of primary male sexual characteristics#GO:0046546;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;system development#GO:0048731;reproductive system development#GO:0061458;intracellular signal transduction#GO:0035556;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;response to chemical#GO:0042221;response to lipid#GO:0033993;sex differentiation#GO:0007548;response to hormone#GO:0009725;animal organ development#GO:0048513;development of primary sexual characteristics#GO:0045137;positive regulation of transcription by RNA polymerase II#GO:0045944;signaling#GO:0023052;reproductive structure development#GO:0048608;cellular response to endogenous stimulus#GO:0071495;gamete generation#GO:0007276;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;hormone-mediated signaling pathway#GO:0009755;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biosynthetic process#GO:0009889;intracellular receptor signaling pathway#GO:0030522;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;steroid hormone receptor signaling pathway#GO:0043401;cellular response to stimulus#GO:0051716;multicellular organismal reproductive process#GO:0048609;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;response to steroid hormone#GO:0048545;positive regulation of macromolecule metabolic process#GO:0010604;cellular response to lipid#GO:0071396;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;male gonad development#GO:0008584;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular response to steroid hormone stimulus#GO:0071383;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 Gonadotropin-releasing hormone receptor pathway#P06664>AR#P06774 MONDO|Ensembl=ENSMODG00000047307.1|UniProtKB=A0A5F8GLR0 A0A5F8GLR0 PTHR26454:SF77 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000046605.1|UniProtKB=F7EXK9 F7EXK9 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000023828.3|UniProtKB=F6UQ46 F6UQ46 TRIM40 PTHR24103:SF564 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN LIGASE TRIM40 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000018090.4|UniProtKB=A0A5F8G4N2 A0A5F8G4N2 PHLDB2 PTHR12156:SF21 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY B MEMBER 2 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 cell cortex#GO:0005938;cell periphery#GO:0071944;basal part of cell#GO:0045178;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 EGF receptor signaling pathway#P00018>Gab#P00563 MONDO|Ensembl=ENSMODG00000008298.3|UniProtKB=F7FTX9 F7FTX9 NKAIN3 PTHR13084:SF2 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 3 regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000008971.4|UniProtKB=F7G201 F7G201 PTHR13375:SF3 FMS INTERACTING PROTEIN THO COMPLEX SUBUNIT 5 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;transcription export complex#GO:0000346;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347 MONDO|Ensembl=ENSMODG00000012072.3|UniProtKB=F7G502 F7G502 TMEM115 PTHR13377:SF3 PLACENTAL PROTEIN 6 TRANSMEMBRANE PROTEIN 115 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000008309.4|UniProtKB=F7FGM8 F7FGM8 SLC22A6 PTHR24064:SF717 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 12-LIKE active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000024196.2|UniProtKB=A0A5F8H6E9 A0A5F8H6E9 CHST14 PTHR12137:SF66 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 14 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238 transferase#PC00220 MONDO|Ensembl=ENSMODG00000017679.4|UniProtKB=F7GFQ3 F7GFQ3 TRMT11 PTHR13370:SF3 RNA METHYLASE-RELATED TRNA (GUANINE(10)-N(2))-METHYLTRANSFERASE TRMT11 transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000013962.2|UniProtKB=F6RS65 F6RS65 COX6B1 PTHR11387:SF34 CYTOCHROME C OXIDASE SUBUNIT 6B CYTOCHROME C OXIDASE SUBUNIT mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000017114.5|UniProtKB=F6U443 F6U443 PHC2 PTHR12247:SF86 POLYCOMB GROUP PROTEIN POLYHOMEOTIC-LIKE PROTEIN 2 protein binding#GO:0005515;histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;PcG protein complex#GO:0031519 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000024098.3|UniProtKB=F6Y1V4 F6Y1V4 LOC100617706 PTHR16320:SF9 SPHINGOMYELINASE FAMILY MEMBER SPHINGOMYELIN PHOSPHODIESTERASE 5 sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;sphingomyelin metabolic process#GO:0006684;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000008611.4|UniProtKB=F6PHA3 F6PHA3 ARID5A PTHR13964:SF25 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 5A double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000003207.3|UniProtKB=A0A5F8HA39 A0A5F8HA39 LOC100020632 PTHR42985:SF10 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 1 monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;lipid localization#GO:0010876;fatty acid transport#GO:0015908;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monocarboxylic acid transport#GO:0015718;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000002519.5|UniProtKB=F7B956 F7B956 STYXL2 PTHR45682:SF4 AGAP008228-PA SERINE_THREONINE_TYROSINE-INTERACTING-LIKE PROTEIN 2 hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000003646.4|UniProtKB=F7B009 F7B009 TRMT13 PTHR12998:SF0 TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 MONDO|Ensembl=ENSMODG00000016770.3|UniProtKB=F7GGC2 F7GGC2 ECHDC3 PTHR43602:SF1 FAMILY NOT NAMED ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000013856.4|UniProtKB=A0A5F8GFV9 A0A5F8GFV9 AKR1D1 PTHR11732:SF211 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER D1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 primary metabolic process#GO:0044238;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;hormone metabolic process#GO:0042445;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;regulation of biological quality#GO:0065008 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000005347.3|UniProtKB=F7CH89 F7CH89 OXA1L PTHR12428:SF66 OXA1 MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977 localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740 transporter#PC00227 MONDO|Ensembl=ENSMODG00000000056.5|UniProtKB=F6RDM8 F6RDM8 PTHR23162:SF7 OUTER DENSE FIBER OF SPERM TAILS 2 PROTEIN BCAP regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of cilium assembly#GO:1902017;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of organelle assembly#GO:1902115;biological regulation#GO:0065007;regulation of cell projection assembly#GO:0060491;negative regulation of biological process#GO:0048519;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087 cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cilium#GO:0005929;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000011613.4|UniProtKB=A0A5F8G2Q0 A0A5F8G2Q0 SLC4A1 PTHR11453:SF12 ANION EXCHANGE PROTEIN BAND 3 ANION TRANSPORT PROTEIN bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804 biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;transmembrane transport#GO:0055085;localization#GO:0051179;regulation of biological quality#GO:0065008;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000011523.4|UniProtKB=F6RHY5 F6RHY5 PTHR46985:SF2 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;signaling receptor activity#GO:0038023;molecular function regulator activity#GO:0098772;peptidase activator activity#GO:0016504;enzyme activator activity#GO:0008047 response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;intrinsic apoptotic signaling pathway#GO:0097193;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;apoptotic signaling pathway#GO:0097190;regulation of innate immune response#GO:0045088;defense response#GO:0006952;positive regulation of response to biotic stimulus#GO:0002833;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;regulation of defense response#GO:0031347;inflammatory response#GO:0006954;regulation of immune response#GO:0050776;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular organelle#GO:0043229;canonical inflammasome complex#GO:0061702;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000016972.4|UniProtKB=F6UM70 F6UM70 EPHA3 PTHR46877:SF12 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 3 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713 neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;axon development#GO:0061564;axon guidance#GO:0007411;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 dendritic tree#GO:0097447;dendrite#GO:0030425;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Angiogenesis#P00005>EphR#P00212 MONDO|Ensembl=ENSMODG00000042653.1|UniProtKB=A0A5F8GVA7 A0A5F8GVA7 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000044024.1|UniProtKB=A0A5F8GDV6 A0A5F8GDV6 PTHR25952:SF256 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000025527.3|UniProtKB=A0A5F8GAY6 A0A5F8GAY6 MGAT4D PTHR12062:SF10 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE-LIKE PROTEIN MGAT4D catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;Golgi stack#GO:0005795;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;Golgi apparatus subcompartment#GO:0098791 transferase#PC00220 MONDO|Ensembl=ENSMODG00000005502.4|UniProtKB=A0A5F8G278 A0A5F8G278 PTBP3 PTHR15592:SF17 MATRIN 3/NUCLEAR PROTEIN 220-RELATED POLYPYRIMIDINE TRACT-BINDING PROTEIN 3 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000014027.3|UniProtKB=F6V9E8 F6V9E8 STMN1 PTHR10104:SF5 STATHMIN STATHMIN protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule polymerization or depolymerization#GO:0031110;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;protein depolymerization#GO:0051261;multicellular organismal process#GO:0032501;microtubule polymerization or depolymerization#GO:0031109;system development#GO:0048731;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;regulation of microtubule-based process#GO:0032886;protein-containing complex disassembly#GO:0032984;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;nervous system development#GO:0007399;microtubule depolymerization#GO:0007019;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;neuron development#GO:0048666;cellular component disassembly#GO:0022411;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043 neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 Cytoskeletal regulation by Rho GTPase#P00016>Op18/stathmin#P00513 MONDO|Ensembl=ENSMODG00000008687.4|UniProtKB=F6PXB1 F6PXB1 PTHR48015:SF11 SERINE/THREONINE-PROTEIN KINASE TAO MISSHAPEN-LIKE KINASE 1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000039144.1|UniProtKB=F6PQN5 F6PQN5 LOC100020149 PTHR18847:SF0 20 KD NUCLEAR CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nitrogen compound transport#GO:0071705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;biosynthetic process#GO:0009058;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;RNA export from nucleus#GO:0006405;transport#GO:0006810;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA transport#GO:0050658;RNA localization#GO:0006403;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;nucleobase-containing compound transport#GO:0015931;regulation of macromolecule metabolic process#GO:0060255;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleocytoplasmic transport#GO:0006913;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;mRNA processing#GO:0006397;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA splicing#GO:0008380;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;RNA metabolic process#GO:0016070 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000018530.3|UniProtKB=F7GL38 F7GL38 DBX2 PTHR24331:SF4 DBX HOMEOBOX PROTEIN DBX2 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 MONDO|Ensembl=ENSMODG00000003040.3|UniProtKB=F6Q0G5 F6Q0G5 ST3GAL3 PTHR13713:SF37 SIALYLTRANSFERASE CMP-N-ACETYLNEURAMINATE-BETA-1,4-GALACTOSIDE ALPHA-2,3-SIALYLTRANSFERASE sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000010481.4|UniProtKB=F7ESK8 F7ESK8 ECHS1 PTHR11941:SF179 ENOYL-COA HYDRATASE-RELATED ENOYL-COA HYDRATASE, MITOCHONDRIAL lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;hydratase#PC00120;lyase#PC00144 MONDO|Ensembl=ENSMODG00000013970.4|UniProtKB=F6R6X5 F6R6X5 GRM4 PTHR24060:SF23 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 4 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;glutamate receptor activity#GO:0008066;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 MONDO|Ensembl=ENSMODG00000007217.2|UniProtKB=A0A5F8GMJ9 A0A5F8GMJ9 PTHR10836:SF111 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491;glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891 primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 Huntington disease#P00029>GAPDH#P00810;Glycolysis#P00024>Glyceraldehyde 3-phosphate dehydrogenase#P00676 MONDO|Ensembl=ENSMODG00000001852.3|UniProtKB=F7AIG6 F7AIG6 PTHR45747:SF3 HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) HISTONE-LYSINE N-METHYLTRANSFERASE EZH2 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;binding#GO:0005488;N-methyltransferase activity#GO:0008170;chromatin binding#GO:0003682;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054 heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814 nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;PcG protein complex#GO:0031519;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000007791.4|UniProtKB=F7A959 F7A959 SYT12 PTHR10024:SF252 SYNAPTOTAGMIN SYNAPTOTAGMIN-12 molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;molecular sensor activity#GO:0140299;protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488;phospholipid binding#GO:0005543 transport#GO:0006810;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of transport#GO:0051049;regulation of localization#GO:0032879;establishment of localization#GO:0051234;localization#GO:0051179;regulation of secretion#GO:0051046;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;regulation of cellular process#GO:0050794 exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 MONDO|Ensembl=ENSMODG00000011807.4|UniProtKB=F7CBC7 F7CBC7 PARP3 PTHR10459:SF66 DNA LIGASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP3 catalytic activity#GO:0003824;transferase activity#GO:0016740;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;site of double-strand break#GO:0035861;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 MONDO|Ensembl=ENSMODG00000041920.1|UniProtKB=A0A5F8HB06 A0A5F8HB06 LOC103105813 PTHR24390:SF290 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 184 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020187.2|UniProtKB=F7GHU0 F7GHU0 LOC100027759 PTHR26452:SF52 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000050241.1|UniProtKB=A0A5F8HH44 A0A5F8HH44 LOC100026802 PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN signaling receptor binding#GO:0005102;binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277;protein binding#GO:0005515 regulation of leukocyte mediated cytotoxicity#GO:0001910;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684 external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000023424.2|UniProtKB=F6ST34 F6ST34 GJB7 PTHR11984:SF26 CONNEXIN GAP JUNCTION BETA-7 PROTEIN wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 regulation of biological process#GO:0050789;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cell communication#GO:0007154 membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell junction#GO:0030054;anchoring junction#GO:0070161 gap junction#PC00105;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000039644.1|UniProtKB=A0A5F8H9J5 A0A5F8H9J5 PTHR23268:SF92 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 3-1 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000041775.1|UniProtKB=A0A5F8GAB1 A0A5F8GAB1 LOC100010922 PTHR24404:SF96 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000010090.3|UniProtKB=F6XM75 F6XM75 PTHR22894:SF1 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF170 MONDO|Ensembl=ENSMODG00000007806.3|UniProtKB=F6ZIL7 F6ZIL7 SHKBP1 PTHR15859:SF5 SETA BINDING PROTEIN 1 SH3KBP1-BINDING PROTEIN 1 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of response to stimulus#GO:0048584;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of signal transduction#GO:0009967;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017421.4|UniProtKB=A0A5F8H999 A0A5F8H999 PTHR20859:SF5 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON GAMMA RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to cytokine#GO:0034097;response to stimulus#GO:0050896;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Interferon-gamma signaling pathway#P00035>IFNGR1#P00959;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cytokine receptor#P00866 MONDO|Ensembl=ENSMODG00000011591.4|UniProtKB=F6UZQ3 F6UZQ3 RUNDC3A PTHR46251:SF4 RUN DOMAIN-CONTAINING 3 PROTEIN RUNDC3 RUN DOMAIN-CONTAINING PROTEIN 3A MONDO|Ensembl=ENSMODG00000012315.4|UniProtKB=F7EIS7 F7EIS7 ZNF516 PTHR45925:SF3 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 516 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000021023.4|UniProtKB=F6QZ07 F6QZ07 PTHR43184:SF11 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A1 organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;phosphate transmembrane transporter activity#GO:0005315;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;inorganic anion transport#GO:0015698;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;organophosphate ester transport#GO:0015748;phosphate ion transport#GO:0006817 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 transporter#PC00227 MONDO|Ensembl=ENSMODG00000019580.4|UniProtKB=F6QMZ0 F6QMZ0 TNFSF8 PTHR32163:SF1 TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 8 TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 8 cell differentiation#GO:0030154;cell development#GO:0048468;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;leukocyte activation#GO:0045321;mononuclear cell differentiation#GO:1903131;anatomical structure development#GO:0048856;immune system process#GO:0002376;cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;hemopoiesis#GO:0030097;T cell differentiation#GO:0030217;cellular process#GO:0009987;cellular developmental process#GO:0048869;developmental process#GO:0032502 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000001196.3|UniProtKB=F7GH85 F7GH85 WNT2B PTHR12027:SF93 WNT RELATED PROTEIN WNT-2B binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;anatomical structure development#GO:0048856;cell fate commitment#GO:0045165;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 MONDO|Ensembl=ENSMODG00000009007.3|UniProtKB=F7BPY5 F7BPY5 ZMAT5 PTHR16465:SF0 NUCLEASE-RELATED ZINC FINGER MATRIN-TYPE PROTEIN 5 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000020246.3|UniProtKB=F7D3X7 F7D3X7 EDIL3 PTHR24543:SF333 MULTICOPPER OXIDASE-RELATED EGF-LIKE REPEAT AND DISCOIDIN I-LIKE DOMAIN-CONTAINING PROTEIN 3 positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000020439.4|UniProtKB=A0A5F8GD17 A0A5F8GD17 NEDD4L PTHR11254:SF443 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;transferase activity#GO:0016740;catalytic activity#GO:0003824;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;transporter regulator activity#GO:0141108;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 regulation of plasma membrane bounded cell projection organization#GO:0120035;macromolecule metabolic process#GO:0043170;regulation of anatomical structure morphogenesis#GO:0022603;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;regulation of cell projection organization#GO:0031344;macromolecule catabolic process#GO:0009057;biological regulation#GO:0065007;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;regulation of developmental process#GO:0050793;primary metabolic process#GO:0044238;regulation of dendrite morphogenesis#GO:0048814;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000047163.1|UniProtKB=A0A5F8GQ57 A0A5F8GQ57 PTHR24377:SF1043 IP01015P-RELATED ZINC FINGER PROTEIN 160-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000007152.4|UniProtKB=F6XPB4 F6XPB4 PTHR11537:SF134 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY B MEMBER 2 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transport#GO:0006813;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;action potential#GO:0001508;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 transporter complex#GO:1990351;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell body#GO:0044297 voltage-gated ion channel#PC00241;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000029240.2|UniProtKB=K7E517 K7E517 PTHR23011:SF32 CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000047751.1|UniProtKB=A0A5F8H7Z8 A0A5F8H7Z8 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000042558.1|UniProtKB=A0A5F8GQ20 A0A5F8GQ20 PTHR13361:SF1 WW DOMAIN-BINDING PROTEIN 11 WW DOMAIN-BINDING PROTEIN 11 enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 MONDO|Ensembl=ENSMODG00000050454.1|UniProtKB=K7E672 K7E672 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000005994.3|UniProtKB=F6SL84 F6SL84 MIXL1 PTHR47656:SF1 HOMEOBOX PROTEIN MIXL HOMEOBOX PROTEIN MIXL1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000045456.1|UniProtKB=A0A5F8H863 A0A5F8H863 PTHR24384:SF261 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 719 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000014723.4|UniProtKB=F6ZD53 F6ZD53 NT5C3B PTHR13045:SF15 5'-NUCLEOTIDASE 7-METHYLGUANOSINE PHOSPHATE-SPECIFIC 5'-NUCLEOTIDASE nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 esterase#PC00097;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000004151.5|UniProtKB=F7B1B4 F7B1B4 CTU2 PTHR20882:SF14 CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2 CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2 sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble position uridine thiolation#GO:0002143;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;tRNA thio-modification#GO:0034227;macromolecule modification#GO:0043412 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000017758.3|UniProtKB=F7E4P6 F7E4P6 GJA1 PTHR11984:SF33 CONNEXIN GAP JUNCTION ALPHA-1 PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 system development#GO:0048731;cell communication#GO:0007154;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;circulatory system development#GO:0072359;heart development#GO:0007507;multicellular organismal process#GO:0032501;regulation of biological process#GO:0050789;cellular process#GO:0009987 cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell junction#GO:0030054;anchoring junction#GO:0070161 cell junction protein#PC00070;gap junction#PC00105 MONDO|Ensembl=ENSMODG00000003284.3|UniProtKB=F7EGB5 F7EGB5 CDH3 PTHR24027:SF446 CADHERIN-23 CADHERIN-3 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell migration#GO:0016477;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622 cadherin#PC00057;cell adhesion molecule#PC00069 Alzheimer disease-presenilin pathway#P00004>E-cadherin transmembrane fragment#P00139;Wnt signaling pathway#P00057>Cadherin#P01440;Alzheimer disease-presenilin pathway#P00004>E-cadherin#P00118;Alzheimer disease-presenilin pathway#P00004>E-cadherin intracellular fragment#P00168;Alzheimer disease-presenilin pathway#P00004>E-cadherin C-terminal fragment#P00117;Alzheimer disease-presenilin pathway#P00004>E-cadherin N-terminal fragment#P00165;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000037635.1|UniProtKB=K7E608 K7E608 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000041427.1|UniProtKB=K7E1Y3 K7E1Y3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000028582.2|UniProtKB=K7E317 K7E317 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000008073.4|UniProtKB=A0A5F8HK47 A0A5F8HK47 FASTKD1 PTHR21228:SF29 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;mitochondrial gene expression#GO:0140053;regulation of RNA metabolic process#GO:0051252;mitochondrial RNA metabolic process#GO:0000959;regulation of RNA stability#GO:0043487;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000013617.3|UniProtKB=F6VE83 F6VE83 POLR2J PTHR13946:SF16 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11-A transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098 RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleic acid biosynthetic process#GO:0141187;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA-templated transcription#GO:0006351;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000018851.3|UniProtKB=A0A5F8GSX6 A0A5F8GSX6 TUBA4A PTHR36527:SF6 OS01G0282866 PROTEIN TUBULIN ALPHA CHAIN MONDO|Ensembl=ENSMODG00000015421.4|UniProtKB=F6SMT5 F6SMT5 USP37 PTHR24006:SF915 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE-RELATED catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 mitotic cell cycle process#GO:1903047;regulation of biological quality#GO:0065008;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of protein stability#GO:0031647;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000004190.4|UniProtKB=F6Y998 F6Y998 C1QL4 PTHR22923:SF67 CEREBELLIN-RELATED COMPLEMENT C1Q-LIKE PROTEIN 4 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000028613.2|UniProtKB=A0A5F8GHX9 A0A5F8GHX9 PTHR38326:SF1 CHROMOSOME 11 OPEN READING FRAME 97 CHROMOSOME 11 OPEN READING FRAME 97 MONDO|Ensembl=ENSMODG00000007116.4|UniProtKB=F6SHF0 F6SHF0 NUP50 PTHR23138:SF141 RAN BINDING PROTEIN NUCLEAR PORE COMPLEX PROTEIN NUP50 protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000051381.1|UniProtKB=A0A5F8G334 A0A5F8G334 PTHR37352:SF1 TESTIS-SPECIFIC GENE 13 PROTEIN TESTIS-SPECIFIC GENE 13 PROTEIN MONDO|Ensembl=ENSMODG00000011945.4|UniProtKB=F7CV32 F7CV32 COL1A1 PTHR24023:SF569 COLLAGEN ALPHA COLLAGEN ALPHA-1(I) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;animal organ morphogenesis#GO:0009887;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;system development#GO:0048731;external encapsulating structure organization#GO:0045229;skeletal system morphogenesis#GO:0048705;cellular process#GO:0009987;multicellular organismal process#GO:0032501;skin development#GO:0043588;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;interstitial matrix#GO:0005614;supramolecular complex#GO:0099080;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000009761.4|UniProtKB=A0A5F8G3Z6 A0A5F8G3Z6 AFAP1L2 PTHR14338:SF4 ACTIN FILAMENT-ASSOCIATED PROTEIN 1 FAMILY MEMBER ACTIN FILAMENT-ASSOCIATED PROTEIN 1-LIKE 2 enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 response to stress#GO:0006950;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;defense response#GO:0006952;positive regulation of signal transduction#GO:0009967;regulation of ERBB signaling pathway#GO:1901184;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;inflammatory response#GO:0006954;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000043895.1|UniProtKB=A0A5F8HBC9 A0A5F8HBC9 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000048889.1|UniProtKB=A0A5F8GY85 A0A5F8GY85 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000004054.5|UniProtKB=F7C3B1 F7C3B1 MRGPRF PTHR11334:SF3 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G PROTEIN-COUPLED RECEPTOR MEMBER F transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000014477.4|UniProtKB=F7A514 F7A514 TXNDC16 PTHR22699:SF1 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 16 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 16 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000010422.5|UniProtKB=A0A5F8H1Y9 A0A5F8H1Y9 GRM6 PTHR24060:SF24 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 6 glutamate receptor activity#GO:0008066;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044 MONDO|Ensembl=ENSMODG00000014987.2|UniProtKB=F7CG75 F7CG75 CCR10 PTHR10489:SF735 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 10 G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;signaling#GO:0023052;locomotion#GO:0040011;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;chemotaxis#GO:0006935;cell communication#GO:0007154;cell chemotaxis#GO:0060326;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000006054.1|UniProtKB=F7FSJ7 F7FSJ7 ZNF706 PTHR21213:SF0 GEO09665P1-RELATED ZINC FINGER PROTEIN 706 MONDO|Ensembl=ENSMODG00000023533.1|UniProtKB=F7GLC4 F7GLC4 LOC100027611 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000016922.4|UniProtKB=F6VN51 F6VN51 CADM2 PTHR45889:SF1 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 2 cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609 cell body#GO:0044297;cell periphery#GO:0071944;membrane#GO:0016020;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000047178.1|UniProtKB=A0A5F8G2W6 A0A5F8G2W6 EFNA2 PTHR11304:SF4 EPHRIN EPHRIN-A2 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;hemopoiesis#GO:0030097;biological regulation#GO:0065007;axon development#GO:0061564;axon guidance#GO:0007411;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;osteoclast differentiation#GO:0030316;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;myeloid cell differentiation#GO:0030099;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell development#GO:0048468;tissue remodeling#GO:0048771;bone remodeling#GO:0046849;signaling#GO:0023052;cellular component organization#GO:0016043;leukocyte differentiation#GO:0002521;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 intercellular signal molecule#PC00207;membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000012996.4|UniProtKB=F7CRL8 F7CRL8 ADAMTSL2 PTHR13723:SF147 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 2 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000019651.4|UniProtKB=F6UAJ6 F6UAJ6 TRIM23 PTHR11711:SF163 ADP RIBOSYLATION FACTOR-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM23 carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;lysosomal membrane#GO:0005765;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 G-protein#PC00020 MONDO|Ensembl=ENSMODG00000043548.1|UniProtKB=A0A5F8GIL2 A0A5F8GIL2 DNAAF3 PTHR22118:SF14 DYNEIN ASSEMBLY FACTOR 3, AXONEMAL DYNEIN AXONEMAL ASSEMBLY FACTOR 3 plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;organelle assembly#GO:0070925;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000013917.4|UniProtKB=F7BG21 F7BG21 SLITRK4 PTHR45773:SF3 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 4 regulation of cell junction assembly#GO:1901888;anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;positive regulation of synapse assembly#GO:0051965;neurogenesis#GO:0022008;axon development#GO:0061564;positive regulation of cellular process#GO:0048522;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;animal gross anatomical part developmental process#GO:0160108;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;regulation of synapse organization#GO:0050807;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;neuron development#GO:0048666;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cell differentiation#GO:0030154;positive regulation of nervous system development#GO:0051962;cell morphogenesis#GO:0000902;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of cellular component biogenesis#GO:0044089;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239 cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cell junction#GO:0030054 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027757.2|UniProtKB=K7E622 K7E622 PTHR16021:SF9 MANSC DOMAIN CONTAINING PROTEIN 1 PROSTATE ANDROGEN-REGULATED MUCIN-LIKE PROTEIN 1 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000006198.2|UniProtKB=A0A5F8GC57 A0A5F8GC57 PAX1 PTHR45636:SF15 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;embryo development ending in birth or egg hatching#GO:0009792;skeletal system development#GO:0001501;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000005549.4|UniProtKB=F7FHD5 F7FHD5 DCAF13 PTHR22851:SF0 U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN DDB1- AND CUL4-ASSOCIATED FACTOR 13 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;biosynthetic process#GO:0009058;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000013028.4|UniProtKB=F7BNL4 F7BNL4 SC5D PTHR11863:SF247 STEROL DESATURASE LATHOSTEROL OXIDASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;secondary alcohol biosynthetic process#GO:1902653;primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 oxidase#PC00175 MONDO|Ensembl=ENSMODG00000011039.4|UniProtKB=F7F450 F7F450 LOC100020228 PTHR11206:SF270 MULTIDRUG RESISTANCE PROTEIN MULTIDRUG AND TOXIN EXTRUSION PROTEIN 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000016172.4|UniProtKB=F7G8Q6 F7G8Q6 POLD2 PTHR10416:SF0 DNA POLYMERASE DELTA SUBUNIT 2 DNA POLYMERASE DELTA SUBUNIT 2 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA-templated DNA replication#GO:0006261;DNA synthesis involved in DNA replication#GO:0090592;response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translesion synthesis#GO:0019985;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;replication fork#GO:0005657;replisome#GO:0030894;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 DNA metabolism protein#PC00009;DNA-directed DNA polymerase#PC00018 DNA replication#P00017>Pol delta#P00533 MONDO|Ensembl=ENSMODG00000018561.2|UniProtKB=F7G261 F7G261 B3GAT2 PTHR10896:SF8 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 2 glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000042128.1|UniProtKB=A0A5F8GTQ4 A0A5F8GTQ4 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000042495.1|UniProtKB=A0A5F8GI40 A0A5F8GI40 ATP6V0C PTHR10263:SF5 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 16 KDA PROTEOLIPID SUBUNIT C membrane#GO:0016020;cellular anatomical structure#GO:0110165 ATP synthase#PC00002;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000004751.4|UniProtKB=F6XIF3 F6XIF3 CFAP96 PTHR31144:SF1 UPF0602 PROTEIN C4ORF47 CILIA-AND FLAGELLA-ASSOCIATED PROTEIN 96 cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoplasmic microtubule#GO:0005881;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000021064.3|UniProtKB=F6V209 F6V209 DNAJC28 PTHR39158:SF2 OS08G0560600 PROTEIN DNAJ HOMOLOG SUBFAMILY C MEMBER 28 temperature homeostasis#GO:0001659;homeostatic process#GO:0042592;multicellular organismal-level homeostasis#GO:0048871;multicellular organismal process#GO:0032501 MONDO|Ensembl=ENSMODG00000005289.3|UniProtKB=A0A5F8GFN5 A0A5F8GFN5 PTHR24377:SF879 IP01015P-RELATED ZINC FINGER PROTEIN 16 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019328.4|UniProtKB=F6XSU6 F6XSU6 NUDT12 PTHR42904:SF6 NUDIX HYDROLASE, NUDC SUBFAMILY NAD-CAPPED RNA HYDROLASE NUDT12 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;pyridine nucleotide catabolic process#GO:0019364;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;NADP+ metabolic process#GO:0006739;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000013213.3|UniProtKB=F7EVY9 F7EVY9 USP2 PTHR21646:SF17 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein stability#GO:0031647;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000008246.4|UniProtKB=F6ZXG2 F6ZXG2 CHRNA10 PTHR18945:SF889 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-10 passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324 detection of stimulus involved in sensory perception#GO:0050906;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;response to stimulus#GO:0050896;sensory perception of sound#GO:0007605;signaling#GO:0023052;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;nervous system process#GO:0050877;synaptic transmission, cholinergic#GO:0007271;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;detection of stimulus#GO:0051606;response to mechanical stimulus#GO:0009612;establishment of localization#GO:0051234;response to external stimulus#GO:0009605;system process#GO:0003008;detection of mechanical stimulus#GO:0050982;transport#GO:0006810;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;chemical synaptic transmission#GO:0007268;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954 transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cell periphery#GO:0071944;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;postsynapse#GO:0098794;membrane protein complex#GO:0098796 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 MONDO|Ensembl=ENSMODG00000020327.4|UniProtKB=F7G7B6 F7G7B6 LIFR PTHR23036:SF105 CYTOKINE RECEPTOR LEUKEMIA INHIBITORY FACTOR RECEPTOR binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000051106.1|UniProtKB=A0A5F8H3S4 A0A5F8H3S4 PTHR39227:SF1 ADIPOGENESIS REGULATORY FACTOR ADIPOGENESIS REGULATORY FACTOR positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of fat cell differentiation#GO:0045600;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000020442.4|UniProtKB=F7AQQ8 F7AQQ8 PTHR34524:SF3 CALCYPHOSIN CALCYPHOSIN-2 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000003363.4|UniProtKB=F7CB79 F7CB79 TUBB6 PTHR11588:SF88 TUBULIN TUBULIN BETA-6 CHAIN guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085;tubulin#PC00228 Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780 MONDO|Ensembl=ENSMODG00000048633.1|UniProtKB=A0A5F8H5F1 A0A5F8H5F1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009371.4|UniProtKB=F7CQ44 F7CQ44 CORO2B PTHR10856:SF17 CORONIN CORONIN-2B actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;focal adhesion assembly#GO:0048041;cell-substrate junction organization#GO:0150115;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell junction organization#GO:0034330;actin cytoskeleton organization#GO:0030036;cellular component organization#GO:0016043;cell-substrate junction assembly#GO:0007044;cell junction assembly#GO:0034329 cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cell periphery#GO:0071944;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin filament#GO:0005884;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000016694.5|UniProtKB=F7DLS0 F7DLS0 PEAR1 PTHR24052:SF12 DELTA-RELATED PLATELET ENDOTHELIAL AGGREGATION RECEPTOR 1 cellular anatomical structure#GO:0110165;membrane#GO:0016020 intercellular signal molecule#PC00207;membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000011635.4|UniProtKB=A0A5F8G285 A0A5F8G285 RPL5 PTHR23410:SF12 RIBOSOMAL PROTEIN L5-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL18 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;ribosomal large subunit assembly#GO:0000027;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of translation#GO:0045727;positive regulation of biosynthetic process#GO:0009891;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of protein metabolic process#GO:0051246;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000045328.1|UniProtKB=A0A5F8HCF1 A0A5F8HCF1 LOC100028408 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038782.1|UniProtKB=A0A5F8HKV6 A0A5F8HKV6 IDUA PTHR12631:SF8 ALPHA-L-IDURONIDASE ALPHA-L-IDURONIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 glycosidase#PC00110;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000046424.1|UniProtKB=A0A5F8HED0 A0A5F8HED0 monDomV1R1272 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009868.5|UniProtKB=F6VV70 F6VV70 NSRP1 PTHR31938:SF4 NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 MONDO|Ensembl=ENSMODG00000012335.4|UniProtKB=F7E2F2 F7E2F2 PTHR24416:SF564 TYROSINE-PROTEIN KINASE RECEPTOR MACROPHAGE-STIMULATING PROTEIN RECEPTOR transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199 cell migration#GO:0016477;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;import into cell#GO:0098657;establishment of localization#GO:0051234;phagocytosis#GO:0006909;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;cell motility#GO:0048870;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;localization#GO:0051179;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018790.4|UniProtKB=F6ZNT2 F6ZNT2 TINAG PTHR12411:SF274 CYSTEINE PROTEASE FAMILY C1-RELATED TUBULOINTERSTITIAL NEPHRITIS ANTIGEN hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000015240.3|UniProtKB=F6UK56 F6UK56 CLIC1 PTHR43920:SF2 CHLORIDE INTRACELLULAR CHANNEL, ISOFORM A CHLORIDE INTRACELLULAR CHANNEL PROTEIN 1 chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 transport#GO:0006810;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000008410.3|UniProtKB=F7BUL8 F7BUL8 GP9 PTHR22650:SF6 GLYCOPROTEIN IB BETA PLATELET GLYCOPROTEIN IX Blood coagulation#P00011>GP IX#P00455 MONDO|Ensembl=ENSMODG00000028039.2|UniProtKB=K7E543 K7E543 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000044779.1|UniProtKB=A0A5F8GVF4 A0A5F8GVF4 LOC100618240 PTHR26450:SF43 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006772.4|UniProtKB=F7BTR9 F7BTR9 PRRX2 PTHR46385:SF3 PAIRED MESODERM HOMEOBOX PROTEIN 1-RELATED PAIRED MESODERM HOMEOBOX PROTEIN 2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>Prx2#P06731 MONDO|Ensembl=ENSMODG00000003964.5|UniProtKB=F7FMU1 F7FMU1 TRIM41 PTHR24103:SF713 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM41 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000041644.1|UniProtKB=A0A5F8H151 A0A5F8H151 PTHR11430:SF71 LIPOCALIN EPIDIDYMAL-SPECIFIC LIPOCALIN-5 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000019009.4|UniProtKB=F7C617 F7C617 PTHR10159:SF111 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 4 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 negative regulation of biological process#GO:0048519;gastrulation#GO:0007369;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of signaling#GO:0023057;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;formation of primary germ layer#GO:0001704;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;endoderm formation#GO:0001706;embryo development#GO:0009790;regulation of MAPK cascade#GO:0043408;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;endoderm development#GO:0007492;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cell communication#GO:0007154;anatomical structure development#GO:0048856;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000019354.4|UniProtKB=F6X979 F6X979 ZSCAN2 PTHR23226:SF469 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015823.4|UniProtKB=F7FDX6 F7FDX6 KANSL1L PTHR22443:SF16 NON-SPECIFIC LETHAL 1, ISOFORM M KAT8 REGULATORY NSL COMPLEX SUBUNIT 1-LIKE PROTEIN protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;NSL complex#GO:0044545;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123 MONDO|Ensembl=ENSMODG00000014377.4|UniProtKB=F6UAD1 F6UAD1 TMTC1 PTHR44809:SF1 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE TMTC1 mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein O-linked glycosylation via mannose#GO:0035269;glycoprotein metabolic process#GO:0009100 MONDO|Ensembl=ENSMODG00000050820.1|UniProtKB=F7B4N9 F7B4N9 LOC100021975 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007898.3|UniProtKB=F6YT37 F6YT37 TIMM9 PTHR13172:SF5 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597 mitochondrial intermembrane space#GO:0005758;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial envelope#GO:0005740;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle lumen#GO:0043233 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000001028.4|UniProtKB=F6ZF84 F6ZF84 FSCN1 PTHR10551:SF23 FASCIN FASCIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cell migration#GO:0016477;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163 neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;lamellipodium#GO:0030027;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;ruffle#GO:0001726;microvillus#GO:0005902;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;axon#GO:0030424;growth cone#GO:0030426;filopodium#GO:0030175;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;cell projection membrane#GO:0031253 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000021434.4|UniProtKB=F7CB49 F7CB49 GNAL PTHR10218:SF233 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(OLF) SUBUNIT ALPHA pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;nervous system process#GO:0050877;sensory perception#GO:0007600;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;sensory perception of chemical stimulus#GO:0007606;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;system process#GO:0003008;G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;biological regulation#GO:0065007 catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 G-protein#PC00020;heterotrimeric G-protein#PC00117 Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gsalpha#P00705;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Endothelin signaling pathway#P00019>Gs#P00584;Enkephalin release#P05913>G-Protein (s)#P05977 MONDO|Ensembl=ENSMODG00000023091.3|UniProtKB=A0A5F8HKS7 A0A5F8HKS7 LOC130453602 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008107.4|UniProtKB=A0A5F8HLE6 A0A5F8HLE6 ARHGAP44 PTHR14130:SF13 3BP-1 RELATED RHOGAP RHO GTPASE-ACTIVATING PROTEIN 44 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of cell projection organization#GO:0031344;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;negative regulation of signal transduction#GO:0009968;regulation of neuron projection development#GO:0010975;regulation of synapse structure or activity#GO:0050803;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of biological quality#GO:0065008;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of dendritic spine morphogenesis#GO:0061001;regulation of synapse organization#GO:0050807;regulation of signaling#GO:0023051;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of postsynapse organization#GO:0099175;regulation of organelle organization#GO:0033043 postsynaptic density#GO:0014069;dendritic tree#GO:0097447;leading edge membrane#GO:0031256;dendrite#GO:0030425;dendritic spine#GO:0043197;postsynapse#GO:0098794;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;presynaptic active zone#GO:0048786;cell junction#GO:0030054;cell periphery#GO:0071944;presynapse#GO:0098793;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572 GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000020080.3|UniProtKB=F7GI68 F7GI68 LOC100025071 PTHR48018:SF90 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AK3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016557.4|UniProtKB=F7E7P9 F7E7P9 PTHR11005:SF15 LYSOSOMAL ACID LIPASE-RELATED GASTRIC TRIACYLGLYCEROL LIPASE hydrolase activity#GO:0016787;triacylglycerol lipase activity#GO:0004806;catalytic activity#GO:0003824;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 lipase#PC00143;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000012661.4|UniProtKB=A0A5F8H1S0 A0A5F8H1S0 PLXDC1 PTHR13055:SF10 TUMOR ENDOTHELIAL MARKER 7 RELATED PLEXIN DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000048230.1|UniProtKB=A0A5F8GED1 A0A5F8GED1 PTHR37873:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 33 SMALL INTEGRAL MEMBRANE PROTEIN 33 MONDO|Ensembl=ENSMODG00000017873.4|UniProtKB=F6YHW6 F6YHW6 CDAN1 PTHR28678:SF1 CODANIN-1 CODANIN-1 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000018028.4|UniProtKB=F7CL56 F7CL56 PTHR24376:SF38 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 544-RELATED zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000025045.2|UniProtKB=F7EB53 F7EB53 GPR18 PTHR24232:SF1 G-PROTEIN COUPLED RECEPTOR N-ARACHIDONYL GLYCINE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013447.4|UniProtKB=F7G9D3 F7G9D3 TBC1D22B PTHR22957:SF462 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 22B GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000003250.4|UniProtKB=A0A5F8HID4 A0A5F8HID4 ARK2N PTHR16200:SF5 RING ZINC FINGER PROTEIN ARK2N acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000002824.4|UniProtKB=F7EJ36 F7EJ36 CORO1C PTHR10856:SF10 CORONIN CORONIN-1C protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cell migration#GO:0016477;tissue development#GO:0009888;neural crest cell development#GO:0014032;cytoskeleton organization#GO:0007010;stem cell differentiation#GO:0048863;organelle organization#GO:0006996;cellular process#GO:0009987;neural crest cell migration#GO:0001755;cellular developmental process#GO:0048869;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;mesenchyme development#GO:0060485;actin filament organization#GO:0007015;mesenchymal cell differentiation#GO:0048762;developmental process#GO:0032502;neural crest cell differentiation#GO:0014033;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;stem cell development#GO:0048864;actin filament-based process#GO:0030029 supramolecular complex#GO:0099080;lamellipodium#GO:0030027;supramolecular polymer#GO:0099081;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;actin filament#GO:0005884;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000019133.3|UniProtKB=A0A5F8GKH1 A0A5F8GKH1 UNC45B PTHR45994:SF2 FI21225P1 PROTEIN UNC-45 HOMOLOG B protein binding#GO:0005515;heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;binding#GO:0005488 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000045208.1|UniProtKB=A0A5F8H2T2 A0A5F8H2T2 WTAP PTHR15217:SF0 WILMS' TUMOR 1-ASSOCIATING PROTEIN PRE-MRNA-SPLICING REGULATOR WTAP enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;mRNA processing#GO:0006397;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000011046.3|UniProtKB=F7EN24 F7EN24 POLI PTHR46404:SF1 DNA POLYMERASE IOTA DNA POLYMERASE IOTA transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;DNA-directed DNA polymerase activity#GO:0003887 cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA synthesis involved in DNA replication#GO:0090592;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000019731.4|UniProtKB=A0A5F8G4G0 A0A5F8G4G0 SCAMP1 PTHR10687:SF8 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 1 transport#GO:0006810;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;secretion by cell#GO:0032940;exocytosis#GO:0006887;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352 organelle membrane#GO:0031090;recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;trans-Golgi network membrane#GO:0032588;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000009194.3|UniProtKB=F6TNC2 F6TNC2 NRBP2 PTHR13902:SF53 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED NUCLEAR RECEPTOR-BINDING PROTEIN 2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000041316.1|UniProtKB=A0A5F8HF67 A0A5F8HF67 monDomV1R1295 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000029434.1|UniProtKB=K7E2L6 K7E2L6 LOC103100453 PTHR35825:SF2 CASEIN KINASE II SUBUNIT ALPHA PRIME-INTERACTING PROTEIN CASEIN KINASE II SUBUNIT ALPHA'-INTERACTING PROTEIN MONDO|Ensembl=ENSMODG00000006565.3|UniProtKB=F7BUJ9 F7BUJ9 CCT6A PTHR11353:SF21 CHAPERONIN CHAPERONIN CONTAINING TCP1 SUBUNIT 6A-RELATED primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031 chaperonin#PC00073 MONDO|Ensembl=ENSMODG00000010526.4|UniProtKB=A0A5F8G302 A0A5F8G302 NEDD9 PTHR10654:SF20 CAS SCAFFOLDING PROTEIN ENHANCER OF FILAMENTATION 1 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell motility#GO:0048870;cell migration#GO:0016477;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000008763.4|UniProtKB=A0A5F8GZ66 A0A5F8GZ66 DNASE1L1 PTHR11371:SF28 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE-1-LIKE 1 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;DNA binding#GO:0003677;nuclease activity#GO:0004518;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519 catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA catabolic process#GO:0006308 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 endodeoxyribonuclease#PC00093 MONDO|Ensembl=ENSMODG00000014956.4|UniProtKB=F7D0E5 F7D0E5 SNAPC3 PTHR13421:SF16 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;core promoter sequence-specific DNA binding#GO:0001046;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase III#GO:0042796;RNA metabolic process#GO:0016070;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;snRNA transcription#GO:0009301;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000019046.4|UniProtKB=F7DKL8 F7DKL8 PTHR24200:SF7 TOUCAN, ISOFORM A MICROTUBULE-ASSOCIATED TUMOR SUPPRESSOR 1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 regulation of cell motility#GO:2000145;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of leukocyte migration#GO:0002685;regulation of response to external stimulus#GO:0032101;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of chemotaxis#GO:0050920 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000013020.4|UniProtKB=F7BP58 F7BP58 SRSF10 PTHR23147:SF5 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 10 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nuclear body#GO:0016604;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nuclear speck#GO:0016607;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000004696.3|UniProtKB=F6XX06 F6XX06 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020622.4|UniProtKB=F7EUQ9 F7EUQ9 CNGA1 PTHR45638:SF9 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL ALPHA-1 ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;gated channel activity#GO:0022836;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;purine ribonucleotide binding#GO:0032555 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;cellular process#GO:0009987;system process#GO:0003008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;sensory perception#GO:0007600;nervous system process#GO:0050877;transport#GO:0006810;sensory perception of chemical stimulus#GO:0007606 cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 MONDO|Ensembl=ENSMODG00000008784.4|UniProtKB=A0A5F8GLT5 A0A5F8GLT5 SGPL1 PTHR42735:SF6 FAMILY NOT NAMED SPHINGOSINE-1-PHOSPHATE LYASE 1 lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;catabolic process#GO:0009056;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;cellular process#GO:0009987;lipid catabolic process#GO:0016042 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000003069.4|UniProtKB=F6PLV1 F6PLV1 NSL1 PTHR31749:SF3 KINETOCHORE-ASSOCIATED PROTEIN NSL1 HOMOLOG KINETOCHORE-ASSOCIATED PROTEIN NSL1 HOMOLOG intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;outer kinetochore#GO:0000940;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000011998.3|UniProtKB=F7B919 F7B919 LOC100027527 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000004108.4|UniProtKB=F6VES9 F6VES9 FGF4 PTHR11486:SF31 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 4 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;fibroblast growth factor receptor binding#GO:0005104;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;response to fibroblast growth factor#GO:0071774;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000042162.1|UniProtKB=A0A5F8H1D6 A0A5F8H1D6 ERI2 PTHR23044:SF84 3'-5' EXONUCLEASE ERI1-RELATED ERI1 EXORIBONUCLEASE 2 3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408 RNA processing#GO:0006396;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of cellular component organization#GO:0051129;rRNA processing#GO:0006364;positive regulation of biosynthetic process#GO:0009891;regulation of chromatin organization#GO:1902275 exoribonuclease#PC00099 MONDO|Ensembl=ENSMODG00000016076.4|UniProtKB=F7G9R7 F7G9R7 PRKCI PTHR24356:SF214 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C IOTA TYPE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;establishment of cell polarity#GO:0030010;protein localization to plasma membrane#GO:0072659;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;localization within membrane#GO:0051668;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;localization#GO:0051179;cell communication#GO:0007154;macromolecule localization#GO:0033036;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;cellular response to insulin stimulus#GO:0032869;intracellular protein localization#GO:0008104;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;protein localization to membrane#GO:0072657;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;establishment or maintenance of cell polarity#GO:0007163;cellular response to chemical stimulus#GO:0070887;cellular localization#GO:0051641;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;response to chemical#GO:0042221;protein localization to cell periphery#GO:1990778 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>PKC#P00565;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Endothelin signaling pathway#P00019>PKC#P00568;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Wnt signaling pathway#P00057>Protein Kinase C#P01458 MONDO|Ensembl=ENSMODG00000003819.4|UniProtKB=F6YVG7 F6YVG7 MAPK4 PTHR24055:SF25 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 4 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099 MONDO|Ensembl=ENSMODG00000025273.1|UniProtKB=F7A3B7 F7A3B7 PTHR26452:SF125 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13A1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000016598.4|UniProtKB=F6ZD99 F6ZD99 NELFCD PTHR12144:SF0 NEGATIVE ELONGATION FACTOR D NEGATIVE ELONGATION FACTOR C_D RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000020451.4|UniProtKB=F7A3D6 F7A3D6 KRR1 PTHR12581:SF0 HIV-1 REV BINDING PROTEIN 2, 3 KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG organelle lumen#GO:0043233;small-subunit processome#GO:0032040;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000004586.4|UniProtKB=F6QJH3 F6QJH3 CEBPE PTHR23334:SF27 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN EPSILON DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;myeloid cell differentiation#GO:0030099;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;cell development#GO:0048468;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;hemopoiesis#GO:0030097;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000039612.1|UniProtKB=A0A5F8GH55 A0A5F8GH55 GEMIN7 PTHR14679:SF1 GEM-ASSOCIATED PROTEIN 7 GEM-ASSOCIATED PROTEIN 7 protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114 MONDO|Ensembl=ENSMODG00000010516.4|UniProtKB=A0A5F8GHL2 A0A5F8GHL2 GRK3 PTHR24355:SF17 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 3 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;G protein-coupled receptor binding#GO:0001664;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;negative regulation of cellular process#GO:0048523 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK3#P05941;Parkinson disease#P00049>GRK#P01234 MONDO|Ensembl=ENSMODG00000016458.4|UniProtKB=F7A3F9 F7A3F9 RBM38 PTHR48024:SF28 GEO13361P1-RELATED RNA-BINDING PROTEIN 38 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000019785.4|UniProtKB=F6W7A8 F6W7A8 PBX3 PTHR11850:SF97 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 3 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837 animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;positive regulation of macromolecule metabolic process#GO:0010604;embryo development#GO:0009790;head development#GO:0060322;nervous system development#GO:0007399;sensory system development#GO:0048880;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;eye development#GO:0001654;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;central nervous system development#GO:0007417;cell development#GO:0048468;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;sensory organ development#GO:0007423;developmental process#GO:0032502;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;embryonic organ development#GO:0048568;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;visual system development#GO:0150063 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000023888.3|UniProtKB=F7ASA2 F7ASA2 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000021240.4|UniProtKB=F6TZS0 F6TZS0 PCOLCE2 PTHR24251:SF31 OVOCHYMASE-RELATED PROCOLLAGEN C-ENDOPEPTIDASE ENHANCER 2 peptidase regulator activity#GO:0061134;collagen binding#GO:0005518;binding#GO:0005488;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234;peptidase activator activity#GO:0016504;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000027512.2|UniProtKB=K7DZ81 K7DZ81 PCP4L1 PTHR15359:SF5 IG-LIKE DOMAIN-CONTAINING PROTEIN PURKINJE CELL PROTEIN 4-LIKE PROTEIN 1 MONDO|Ensembl=ENSMODG00000012179.4|UniProtKB=F6W8U5 F6W8U5 PTHR10828:SF64 M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25 M-PHASE INDUCER PHOSPHATASE 3 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic cell cycle phase transition#GO:0044772;G2/M transition of mitotic cell cycle#GO:0000086;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cell cycle#GO:0051726;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cell cycle process#GO:0022402;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047;regulation of reproductive process#GO:2000241;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cell cycle G2/M phase transition#GO:0044839;positive regulation of cellular process#GO:0048522 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;protein phosphatase#PC00195 p53 pathway#P00059>Cdc25C#P04624 MONDO|Ensembl=ENSMODG00000015367.4|UniProtKB=A0A5F8H7P6 A0A5F8H7P6 HEATR5B PTHR21663:SF2 HYPOTHETICAL HEAT DOMAIN-CONTAINING HEAT REPEAT-CONTAINING PROTEIN 5B transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000014414.4|UniProtKB=A0A5F8GJ89 A0A5F8GJ89 CCDC91 PTHR35072:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 91 COILED-COIL DOMAIN-CONTAINING PROTEIN 91 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;lysosomal transport#GO:0007041;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034;Golgi to vacuole transport#GO:0006896;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791 MONDO|Ensembl=ENSMODG00000018414.4|UniProtKB=F6XV06 F6XV06 BCKDHB PTHR42980:SF1 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL protein-containing complex#GO:0032991;oxidoreductase complex#GO:1990204;transferase complex#GO:1990234;catalytic complex#GO:1902494 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000042332.1|UniProtKB=F6PHR9 F6PHR9 PTHR14672:SF1 MUCIN-16 MUCIN-16 MONDO|Ensembl=ENSMODG00000011049.4|UniProtKB=F7F4J2 F7F4J2 FBXO44 PTHR12125:SF12 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX PROTEIN 44 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000039686.1|UniProtKB=A0A5F8GPX0 A0A5F8GPX0 PTHR13080:SF16 ATP SYNTHASE F CHAIN, MITOCHONDRIAL-RELATED ATP SYNTHASE F(0) COMPLEX SUBUNIT F, MITOCHONDRIAL monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252 primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;oxidative phosphorylation#GO:0006119;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;ATP biosynthetic process#GO:0006754;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086 catalytic complex#GO:1902494;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000044346.1|UniProtKB=A0A5F8GDW4 A0A5F8GDW4 F11R PTHR45113:SF1 JUNCTIONAL ADHESION MOLECULE A JUNCTIONAL ADHESION MOLECULE A cell development#GO:0048468;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;cellular process#GO:0009987;biological regulation#GO:0065007;digestion#GO:0007586;epithelium development#GO:0060429;regulation of membrane permeability#GO:0090559;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;endothelial cell differentiation#GO:0045446;developmental process#GO:0032502;system process#GO:0003008;cellular developmental process#GO:0048869 cell-cell junction#GO:0005911;apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cell junction#GO:0030054 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000038210.1|UniProtKB=F6QLG5 F6QLG5 PTHR48001:SF39 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040907.1|UniProtKB=A0A5F8HHV4 A0A5F8HHV4 PTHR48188:SF3 60S RIBOSOMAL PROTEIN L43 60S RIBOSOMAL PROTEIN L37A large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000013460.4|UniProtKB=F7FYY8 F7FYY8 SNCAIP PTHR22882:SF3 SYNPHILIN-1 SYNPHILIN-1 enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515 Parkinson disease#P00049>Synphilin#P01225 MONDO|Ensembl=ENSMODG00000040994.1|UniProtKB=A0A5F8GYD4 A0A5F8GYD4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000014425.4|UniProtKB=F7E7M6 F7E7M6 LOC100013359 PTHR24291:SF198 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4F11 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000025354.1|UniProtKB=F7E651 F7E651 KCNE1 PTHR15282:SF10 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1 monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel regulator activity#GO:0016247;channel activity#GO:0015267;transmembrane transporter binding#GO:0044325;potassium channel activity#GO:0005267;transporter regulator activity#GO:0141108;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;protein binding#GO:0005515;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;binding#GO:0005488;voltage-gated potassium channel activity#GO:0005249;potassium channel regulator activity#GO:0015459;gated channel activity#GO:0022836 biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;blood circulation#GO:0008015;potassium ion transport#GO:0006813;multicellular organismal process#GO:0032501;actin filament-based movement#GO:0030048;heart contraction#GO:0060047;system process#GO:0003008;establishment of localization#GO:0051234;cardiac muscle cell contraction#GO:0086003;muscle contraction#GO:0006936;transport#GO:0006810;regulation of system process#GO:0044057;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;regulation of heart contraction#GO:0008016;actin-mediated cell contraction#GO:0070252;monoatomic cation transport#GO:0006812;localization#GO:0051179;cardiac muscle contraction#GO:0060048;actin filament-based process#GO:0030029;circulatory system process#GO:0003013;monoatomic cation transmembrane transport#GO:0098655;regulation of multicellular organismal process#GO:0051239;cardiac muscle cell action potential involved in contraction#GO:0086002;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;export from cell#GO:0140352;muscle system process#GO:0003012;action potential#GO:0001508;regulation of biological process#GO:0050789;heart process#GO:0003015;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000011590.3|UniProtKB=F6UZR4 F6UZR4 GLA PTHR11452:SF14 ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE ALPHA-GALACTOSIDASE A hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;galactosidase#PC00104 MONDO|Ensembl=ENSMODG00000049468.1|UniProtKB=A0A5F8GLJ1 A0A5F8GLJ1 AEN PTHR12801:SF57 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED APOPTOSIS-ENHANCING NUCLEASE hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;catalytic activity#GO:0003824;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;signaling#GO:0023052;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;RNA metabolic process#GO:0016070;intrinsic apoptotic signaling pathway#GO:0097193;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;nucleic acid metabolic process#GO:0090304;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;cell death#GO:0008219;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031;exoribonuclease#PC00099 MONDO|Ensembl=ENSMODG00000008667.4|UniProtKB=F6PG00 F6PG00 ADAP1 PTHR46021:SF5 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1 phospholipid binding#GO:0005543;enzyme activator activity#GO:0008047;phosphatidylinositol phosphate binding#GO:1901981;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;enzyme regulator activity#GO:0030234;lipid binding#GO:0008289;molecular function activator activity#GO:0140677 organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000005173.3|UniProtKB=F7E7H8 F7E7H8 EIF3G PTHR10352:SF88 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 MONDO|Ensembl=ENSMODG00000015032.3|UniProtKB=F7BXC0 F7BXC0 PTHR10408:SF6 STEROL O-ACYLTRANSFERASE STEROL O-ACYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;alcohol binding#GO:0043178;steroid binding#GO:0005496;heterocyclic compound binding#GO:1901363;transferase activity#GO:0016740;catalytic activity#GO:0003824;cholesterol binding#GO:0015485;lipid binding#GO:0008289;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;sterol binding#GO:0032934;acyltransferase activity#GO:0016746;ion binding#GO:0043167 lipid transport#GO:0006869;steroid metabolic process#GO:0008202;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;cholesterol efflux#GO:0033344;cellular process#GO:0009987;sterol metabolic process#GO:0016125;sterol transport#GO:0015918;establishment of localization#GO:0051234;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;cholesterol metabolic process#GO:0008203;transport#GO:0006810;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;primary metabolic process#GO:0044238;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 acyltransferase#PC00042;transferase#PC00220 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 MONDO|Ensembl=ENSMODG00000024953.3|UniProtKB=F6UTN9 F6UTN9 VXN PTHR31520:SF1 VEXIN VEXIN nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;cellular process#GO:0009987;neurogenesis#GO:0022008;system development#GO:0048731;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;generation of neurons#GO:0048699;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 MONDO|Ensembl=ENSMODG00000010120.5|UniProtKB=F6WNN6 F6WNN6 CHRNA6 PTHR18945:SF82 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-6 postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;acetylcholine receptor activity#GO:0015464;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315 response to nitrogen compound#GO:1901698;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;trans-synaptic signaling#GO:0099537;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;transport#GO:0006810;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;neuromuscular synaptic transmission#GO:0007274;response to chemical#GO:0042221;regulation of trans-synaptic signaling#GO:0099177;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536 cell junction#GO:0030054;transporter complex#GO:1990351;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;cellular anatomical structure#GO:0110165;synapse#GO:0045202;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNA6#P06592;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 MONDO|Ensembl=ENSMODG00000010493.3|UniProtKB=A0A5F8GI73 A0A5F8GI73 CALY PTHR28546:SF1 NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2-RELATED NEURON-SPECIFIC VESICULAR PROTEIN CALCYON localization#GO:0051179;macromolecule metabolic process#GO:0043170;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031;regulation of biological quality#GO:0065008;metabolic process#GO:0008152;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;transport#GO:0006810;biological regulation#GO:0065007;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000010920.4|UniProtKB=F7F511 F7F511 CAP2 PTHR10652:SF2 ADENYLYL CYCLASE-ASSOCIATED PROTEIN ADENYLYL CYCLASE-ASSOCIATED PROTEIN 2 protein binding#GO:0005515;enzyme binding#GO:0019899;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;developmental process#GO:0032502;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000010872.4|UniProtKB=A0A5F8HH73 A0A5F8HH73 ITGB3 PTHR10082:SF25 INTEGRIN BETA SUBUNIT INTEGRIN BETA-3 binding#GO:0005488;signaling receptor binding#GO:0005102;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178 cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;regulation of biological quality#GO:0065008;wound healing#GO:0042060;cell activation#GO:0001775;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;signaling#GO:0023052;integrin-mediated signaling pathway#GO:0007229;hemostasis#GO:0007599;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;platelet activation#GO:0030168;blood coagulation#GO:0007596;cell surface receptor signaling pathway#GO:0007166;platelet aggregation#GO:0070527;cell adhesion mediated by integrin#GO:0033627;cell migration#GO:0016477;multicellular organismal process#GO:0032501;homotypic cell-cell adhesion#GO:0034109;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;response to stress#GO:0006950;response to wounding#GO:0009611;cellular process#GO:0009987;coagulation#GO:0050817;signal transduction#GO:0007165 anchoring junction#GO:0070161;integrin complex#GO:0008305;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;membrane protein complex#GO:0098796;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;synapse#GO:0045202;signaling receptor complex#GO:0043235;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;protein-containing complex#GO:0032991 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931;Blood coagulation#P00011>GP IIIa#P00458 MONDO|Ensembl=ENSMODG00000048576.1|UniProtKB=A0A5F8G727 A0A5F8G727 PTHR35247:SF1 TESTIS-EXPRESSED PROTEIN 43 TESTIS EXPRESSED 43 MONDO|Ensembl=ENSMODG00000000383.4|UniProtKB=F6R8H7 F6R8H7 MED17 PTHR13114:SF7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000015356.4|UniProtKB=F6WXJ4 F6WXJ4 WSB2 PTHR15622:SF1 WD40 REPEAT PROTEIN WD REPEAT AND SOCS BOX-CONTAINING PROTEIN 2 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000019142.4|UniProtKB=F7ECA6 F7ECA6 GNA11 PTHR10218:SF328 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-11 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;biological regulation#GO:0065007;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of membrane potential#GO:0042391;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;action potential#GO:0001508;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;regulation of biological quality#GO:0065008;response to nitrogen compound#GO:1901698 side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 heterotrimeric G-protein#PC00117;G-protein#PC00020 Wnt signaling pathway#P00057>Galpha#P01451;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057;Gonadotropin-releasing hormone receptor pathway#P06664>gnaq/11#P06841;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Endothelin signaling pathway#P00019>Gq#P00586;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Alpha adrenergic receptor signaling pathway#P00002>G-Protein#P00077 MONDO|Ensembl=ENSMODG00000007835.2|UniProtKB=F7ETE4 F7ETE4 CDK3 PTHR24056:SF462 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 3 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 biological regulation#GO:0065007;signal transduction#GO:0007165;cell cycle G2/M phase transition#GO:0044839;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;G2/M transition of mitotic cell cycle#GO:0000086;cell cycle phase transition#GO:0044770;signaling#GO:0023052;cell cycle#GO:0007049;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;mitotic cell cycle phase transition#GO:0044772 protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000009905.4|UniProtKB=F6UUU8 F6UUU8 CUBN PTHR47537:SF9 CUBILIN CUBILIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000049009.1|UniProtKB=A0A5F8G907 A0A5F8G907 PTHR23304:SF189 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000046425.1|UniProtKB=A0A5F8GK95 A0A5F8GK95 PTHR19306:SF6 STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6 DNA binding#GO:0003677;damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;site of double-strand break#GO:0035861;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000010350.4|UniProtKB=F6RQ32 F6RQ32 LRATD1 PTHR46341:SF1 PROTEIN FAM84B-RELATED PROTEIN LRATD1 cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;anatomical structure development#GO:0048856;cell motility#GO:0048870;cell morphogenesis#GO:0000902 MONDO|Ensembl=ENSMODG00000006104.4|UniProtKB=F7AJN8 F7AJN8 CARM1 PTHR11006:SF51 PROTEIN ARGININE N-METHYLTRANSFERASE HISTONE-ARGININE METHYLTRANSFERASE CARM1 histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000044996.1|UniProtKB=A0A5F8GAK6 A0A5F8GAK6 PTHR12856:SF0 TRANSCRIPTION INITIATION FACTOR IIH-RELATED GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 1 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;biosynthetic process#GO:0009058;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription factor TFIIH holo complex#GO:0005675;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;transcription factor TFIIH core complex#GO:0000439 RNA metabolism protein#PC00031;general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392;General transcription regulation#P00023>TFIIH complex#P00664 MONDO|Ensembl=ENSMODG00000002521.4|UniProtKB=A0A5F8GAQ8 A0A5F8GAQ8 BAIAP2 PTHR14206:SF3 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 BAR_IMD DOMAIN-CONTAINING ADAPTER PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of supramolecular fiber organization#GO:1902903;actin filament bundle assembly#GO:0051017;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;actin filament bundle organization#GO:0061572;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000043964.1|UniProtKB=A0A5F8GTZ5 A0A5F8GTZ5 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000046240.1|UniProtKB=A0A5F8G4Q5 A0A5F8G4Q5 VPS37B PTHR13678:SF9 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37B protein localization to organelle#GO:0033365;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to vacuole#GO:0072665;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;macromolecule localization#GO:0033036;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;protein transport#GO:0015031;cellular localization#GO:0051641;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein targeting to vacuole#GO:0006623;establishment of protein localization to membrane#GO:0090150;intracellular protein transport#GO:0006886;macromolecule catabolic process#GO:0009057;protein targeting to membrane#GO:0006612;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;ESCRT I complex#GO:0000813;vesicle membrane#GO:0012506 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000018642.4|UniProtKB=F7B290 F7B290 UGGT1 PTHR11226:SF3 UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;glucosyltransferase activity#GO:0046527 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000021562.2|UniProtKB=O78703 O78703 MT-ND1 PTHR11432:SF23 NADH DEHYDROGENASE SUBUNIT 1 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;NADH dehydrogenase activity#GO:0003954 energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987 respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000000770.4|UniProtKB=F6SSU1 F6SSU1 BTF3L4 PTHR10351:SF29 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 HOMOLOG 4 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000023786.2|UniProtKB=F7EFD6 F7EFD6 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009690.4|UniProtKB=F6YBF4 F6YBF4 CCDC73 PTHR28660:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 73 COILED-COIL DOMAIN-CONTAINING PROTEIN 73 MONDO|Ensembl=ENSMODG00000041649.1|UniProtKB=F6S7K6 F6S7K6 PTHR24028:SF318 CADHERIN-87A PROTOCADHERIN BETA-16 cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000013560.4|UniProtKB=F7C2Y2 F7C2Y2 PTHR24253:SF31 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 4 serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000017463.4|UniProtKB=A0A5F8HFJ1 A0A5F8HFJ1 PDE7B PTHR11347:SF72 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 7B cyclic-nucleotide phosphodiesterase activity#GO:0004112;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 hydrolase#PC00121;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000011168.4|UniProtKB=F6ZZR2 F6ZZR2 RB1 PTHR13742:SF36 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RETINOBLASTOMA-ASSOCIATED PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular process#GO:0050794;regulation of cell cycle phase transition#GO:1901987;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;negative regulation of cell cycle process#GO:0010948;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of mitotic cell cycle#GO:0007346;neuron development#GO:0048666;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of cell cycle#GO:0051726;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;regulation of cell cycle process#GO:0010564;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;neuron projection development#GO:0031175 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;RNA polymerase II transcription regulator complex#GO:0090575;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 p53 pathway feedback loops 2#P04398>Rb#P04654 MONDO|Ensembl=ENSMODG00000000610.2|UniProtKB=F6TB25 F6TB25 PTHR14403:SF6 RFAMIDE PEPTIDE GONADOTROPIN INHIBITORY HORMONE PRO-FMRFAMIDE-RELATED NEUROPEPTIDE VF protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;cellular response to stimulus#GO:0051716;negative regulation of transport#GO:0051051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of secretion#GO:0051046;regulation of hormone secretion#GO:0046883;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;negative regulation of cell communication#GO:0010648;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of system process#GO:0044057;negative regulation of cellular process#GO:0048523;regulation of localization#GO:0032879;regulation of transport#GO:0051049 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>RFRP-1/-3#P06828 MONDO|Ensembl=ENSMODG00000013661.3|UniProtKB=F6TXY0 F6TXY0 UBE2C PTHR24068:SF144 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 C-RELATED ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of cell cycle phase transition#GO:1901987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of chromosome organization#GO:0033044;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;modification-dependent macromolecule catabolic process#GO:0043632;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of chromosome segregation#GO:0051983;cellular process#GO:0009987;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;proteasomal protein catabolic process#GO:0010498 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000017428.4|UniProtKB=F6ZVE4 F6ZVE4 ZBTB8B PTHR24394:SF33 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 8B transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018368.4|UniProtKB=F6RFT4 F6RFT4 PTHR24037:SF3 HEART DEVELOPMENT PROTEIN WITH EGF-LIKE DOMAINS 1 PROTEIN HEG HOMOLOG 1 multicellular organismal process#GO:0032501;circulatory system development#GO:0072359;heart development#GO:0007507;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 MONDO|Ensembl=ENSMODG00000018813.4|UniProtKB=F6Z024 F6Z024 LOC100014035 PTHR11571:SF282 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE-RELATED transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740 xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;glutathione metabolic process#GO:0006749 transferase#PC00220 MONDO|Ensembl=ENSMODG00000005275.4|UniProtKB=F7G859 F7G859 LOC100617195 PTHR23226:SF85 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 397 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004723.4|UniProtKB=F6Y251 F6Y251 ABCA4 PTHR19229:SF190 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA RETINAL-SPECIFIC PHOSPHOLIPID-TRANSPORTING ATPASE ABCA4 transmembrane transporter activity#GO:0022857;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;intramembrane lipid carrier activity#GO:0140303 macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810;lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000037008.1|UniProtKB=A0A5F8GBC6 A0A5F8GBC6 PTHR11258:SF13 2-5 OLIGOADENYLATE SYNTHETASE 2'-5'-OLIGOADENYLATE SYNTHASE 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;adenylyltransferase activity#GO:0070566;double-stranded RNA binding#GO:0003725;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;antiviral innate immune response#GO:0140374;response to virus#GO:0009615;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;negative regulation of biological process#GO:0048519;defense response to virus#GO:0051607;response to peptide#GO:1901652;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376 nucleus#GO:0005634;cytosol#GO:0005829;organelle lumen#GO:0043233;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;nucleotidyltransferase#PC00174 MONDO|Ensembl=ENSMODG00000044853.1|UniProtKB=A0A5F8HAF4 A0A5F8HAF4 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000013310.3|UniProtKB=F6YWE2 F6YWE2 LOC100027455 PTHR24241:SF127 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 22 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028526.2|UniProtKB=K7E1F8 K7E1F8 PTHR33166:SF1 GAG_P30 DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000049884.1|UniProtKB=A0A5F8G8Y6 A0A5F8G8Y6 VMAC PTHR34707:SF1 VIMENTIN-TYPE INTERMEDIATE FILAMENT-ASSOCIATED COILED-COIL PROTEIN VIMENTIN-TYPE INTERMEDIATE FILAMENT-ASSOCIATED COILED-COIL PROTEIN MONDO|Ensembl=ENSMODG00000017260.5|UniProtKB=A0A5F8GQV5 A0A5F8GQV5 PTHR10030:SF45 ALPHA-L-FUCOSIDASE PLASMA ALPHA-L-FUCOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136 hydrolase#PC00121;glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000041423.1|UniProtKB=A0A5F8H014 A0A5F8H014 SMIM14 PTHR31019:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 14 SMALL INTEGRAL MEMBRANE PROTEIN 14 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000001657.4|UniProtKB=F6T722 F6T722 KATNBL1 PTHR14682:SF1 KATNB1-LIKE PROTEIN 1 KATNB1-LIKE PROTEIN 1 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cytoplasmic microtubule organization#GO:0031122;microtubule-based process#GO:0007017;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000001820.4|UniProtKB=A0A5F8HH71 A0A5F8HH71 TMC8 PTHR23302:SF39 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 8 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000040529.1|UniProtKB=A0A5F8G9W5 A0A5F8G9W5 PTHR12081:SF19 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F6 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000043664.1|UniProtKB=A0A5F8GHV7 A0A5F8GHV7 PTHR28675:SF2 MELANOCORTIN-2 RECEPTOR ACCESSORY PROTEIN 2 MELANOCORTIN-2 RECEPTOR ACCESSORY PROTEIN protein binding#GO:0005515;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;cellular localization#GO:0051641;localization#GO:0051179;regulation of signaling#GO:0023051;localization within membrane#GO:0051668;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;protein localization to cell periphery#GO:1990778 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000000002.3|UniProtKB=F6SJ85 F6SJ85 PTHR23105:SF101 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000000676.4|UniProtKB=A0A5F8G8B1 A0A5F8G8B1 PTHR12181:SF62 LIPIN PHOSPHATIDATE PHOSPHATASE LPIN3 transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;transcription coactivator activity#GO:0003713;phosphoric ester hydrolase activity#GO:0042578;transcription regulator activity#GO:0140110;hydrolase activity#GO:0016787 positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;response to hormone#GO:0009725;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;lipid catabolic process#GO:0016042;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;fatty acid catabolic process#GO:0009062;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;response to oxygen-containing compound#GO:1901700;cellular response to hormone stimulus#GO:0032870;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;response to endogenous stimulus#GO:0009719;monocarboxylic acid metabolic process#GO:0032787;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;neutral lipid metabolic process#GO:0006638;regulation of gene expression#GO:0010468;fatty acid metabolic process#GO:0006631;acylglycerol metabolic process#GO:0006639;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;cellular response to insulin stimulus#GO:0032869;positive regulation of DNA-templated transcription#GO:0045893;cellular response to nitrogen compound#GO:1901699;monocarboxylic acid catabolic process#GO:0072329;lipid biosynthetic process#GO:0008610;regulation of nucleobase-containing compound metabolic process#GO:0019219;triglyceride biosynthetic process#GO:0019432;response to peptide hormone#GO:0043434;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;glycerolipid biosynthetic process#GO:0045017;positive regulation of cellular process#GO:0048522;carboxylic acid catabolic process#GO:0046395;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;cellular response to peptide hormone stimulus#GO:0071375;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000006569.4|UniProtKB=A0A5F8HDT8 A0A5F8HDT8 ZNF704 PTHR13006:SF7 PAPILLOMAVIRUS REGULATORY FACTOR PRF-1 ZINC FINGER PROTEIN 704 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000031298.2|UniProtKB=A0A5F8HKU4 A0A5F8HKU4 PTHR47494:SF1 NKG2-D TYPE II INTEGRAL MEMBRANE PROTEIN NKG2-D TYPE II INTEGRAL MEMBRANE PROTEIN MONDO|Ensembl=ENSMODG00000009265.4|UniProtKB=F7DAM2 F7DAM2 ALOX5AP PTHR10250:SF2 MICROSOMAL GLUTATHIONE S-TRANSFERASE ARACHIDONATE 5-LIPOXYGENASE-ACTIVATING PROTEIN transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;glutathione transferase activity#GO:0004364;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;carbon-sulfur lyase activity#GO:0016846;lyase activity#GO:0016829 biosynthetic process#GO:0009058;icosanoid biosynthetic process#GO:0046456;small molecule metabolic process#GO:0044281;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 transferase#PC00220 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Lipoxygenase#P00830 MONDO|Ensembl=ENSMODG00000003510.3|UniProtKB=F7C8F9 F7C8F9 CRLF1 PTHR23036:SF16 CYTOKINE RECEPTOR CYTOKINE RECEPTOR-LIKE FACTOR 1 immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of biological process#GO:0048519;positive regulation of cell population proliferation#GO:0008284;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;negative regulation of apoptotic process#GO:0043066;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;negative regulation of neuron apoptotic process#GO:0043524;regulation of neuron apoptotic process#GO:0043523;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166 extracellular protein-containing complex#GO:0140392;signaling receptor complex#GO:0043235;extracellular region#GO:0005576;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037660.1|UniProtKB=A0A5F8G6P8 A0A5F8G6P8 GRIFIN PTHR11346:SF21 GALECTIN GRIFIN carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000007262.5|UniProtKB=A0A5F8GSK9 A0A5F8GSK9 GBA2 PTHR12654:SF33 BILE ACID BETA-GLUCOSIDASE-RELATED NON-LYSOSOMAL GLUCOSYLCERAMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;glucosidase activity#GO:0015926;beta-glucosidase activity#GO:0008422;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;central nervous system development#GO:0007417;multicellular organismal process#GO:0032501 glucosidase#PC00108;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000011668.4|UniProtKB=F6YE86 F6YE86 PDC PTHR46052:SF3 PHOSDUCIN-LIKE PROTEIN PHOSDUCIN cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;9+0 non-motile cilium#GO:0097731;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Phosducin#P00758 MONDO|Ensembl=ENSMODG00000009056.4|UniProtKB=F7FR06 F7FR06 ABCB10 PTHR19879:SF6 TRANSCRIPTION INITIATION FACTOR TFIID TAF5-LIKE RNA POLYMERASE II P300_CBP-ASSOCIATED FACTOR-ASSOCIATED FACTOR 65 KDA SUBUNIT 5L protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;transcription initiation at RNA polymerase II promoter#GO:0006367;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 SAGA complex#GO:0000124;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transcription factor TFIID complex#GO:0005669;nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;peptidase complex#GO:1905368;transferase complex#GO:1990234;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;SAGA-type complex#GO:0070461;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428 MONDO|Ensembl=ENSMODG00000017429.4|UniProtKB=F6ZVC6 F6ZVC6 IL20RA PTHR20859:SF86 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-20 RECEPTOR SUBUNIT ALPHA binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023 response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 MONDO|Ensembl=ENSMODG00000028135.2|UniProtKB=A0A5F8H8H4 A0A5F8H8H4 PTHR10624:SF6 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR-RELATED UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Plasminogen activating cascade#P00050>uPAR#P01256;Blood coagulation#P00011>uPAR#P00433 MONDO|Ensembl=ENSMODG00000002119.3|UniProtKB=F6UG38 F6UG38 FSTL5 PTHR10913:SF44 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 5 developmental process#GO:0032502;cellular process#GO:0009987;cell differentiation#GO:0030154;cellular developmental process#GO:0048869 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000028145.2|UniProtKB=K7E0A4 K7E0A4 PTHR45747:SF3 HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) HISTONE-LYSINE N-METHYLTRANSFERASE EZH2 protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;chromatin binding#GO:0003682;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;binding#GO:0005488;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000000421.4|UniProtKB=F6VAP2 F6VAP2 CTBS PTHR46290:SF8 DI-N-ACETYLCHITOBIASE DI-N-ACETYLCHITOBIASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;amino sugar catabolic process#GO:0046348;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;chitin metabolic process#GO:0006030;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;amino sugar metabolic process#GO:0006040;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;carbohydrate catabolic process#GO:0016052;aminoglycan metabolic process#GO:0006022 MONDO|Ensembl=ENSMODG00000017408.4|UniProtKB=F6SK34 F6SK34 NHSL3 PTHR23039:SF6 NANCE-HORAN SYNDROME PROTEIN NHS-LIKE PROTEIN 3 MONDO|Ensembl=ENSMODG00000008827.4|UniProtKB=F6XUS9 F6XUS9 KPTN PTHR15435:SF2 KICSTOR COMPLEX PROTEIN KAPTIN KICSTOR COMPLEX PROTEIN KAPTIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to starvation#GO:0042594;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;cellular response to amino acid starvation#GO:0034198;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;response to stress#GO:0006950;response to nutrient levels#GO:0031667;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;negative regulation of TORC1 signaling#GO:1904262;cellular response to nutrient levels#GO:0031669;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;cell leading edge#GO:0031252 MONDO|Ensembl=ENSMODG00000009488.4|UniProtKB=F7FN86 F7FN86 EEA1 PTHR23164:SF30 EARLY ENDOSOME ANTIGEN 1 EARLY ENDOSOME ANTIGEN 1 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;endocytosis#GO:0006897;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000018949.3|UniProtKB=F7GAR7 F7GAR7 FABP2 PTHR11955:SF89 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, INTESTINAL organic acid binding#GO:0043177;binding#GO:0005488;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;ion binding#GO:0043167;lipid binding#GO:0008289;fatty acid binding#GO:0005504 establishment of localization#GO:0051234;localization#GO:0051179;fatty acid transport#GO:0015908;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;lipid transport#GO:0006869;macromolecule localization#GO:0033036 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000014067.3|UniProtKB=F6TSW3 F6TSW3 USB1 PTHR13522:SF3 U6 SNRNA PHOSPHODIESTERASE 1 U6 SNRNA PHOSPHODIESTERASE 1 3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000029605.2|UniProtKB=K7E133 K7E133 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000006359.4|UniProtKB=F6ZQY7 F6ZQY7 ADARB2 PTHR10910:SF17 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN INACTIVE DOUBLE-STRANDED RNA-SPECIFIC EDITASE B2 tRNA-specific adenosine deaminase activity#GO:0008251;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on a tRNA#GO:0140101;adenosine deaminase activity#GO:0004000;hydrolase activity#GO:0016787;RNA binding#GO:0003723;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity, acting on RNA#GO:0140098;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;base conversion or substitution editing#GO:0016553;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;adenosine to inosine editing#GO:0006382;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000020891.4|UniProtKB=H9H7Q5 H9H7Q5 PHF8 PTHR23123:SF11 PHD/F-BOX CONTAINING PROTEIN HISTONE LYSINE DEMETHYLASE PHF8 catalytic activity#GO:0003824;histone demethylase activity#GO:0032452;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;protein demethylase activity#GO:0140457;histone modifying activity#GO:0140993 chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000051576.1|UniProtKB=A0A5F8GTH8 A0A5F8GTH8 PTHR26450:SF177 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52I1-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000044676.1|UniProtKB=K7E1Q9 K7E1Q9 PTHR46890:SF56 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED OS06G0484800 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000006521.4|UniProtKB=F7E3N2 F7E3N2 PFKP PTHR13697:SF5 PHOSPHOFRUCTOKINASE ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, PLATELET TYPE phosphotransferase activity, alcohol group as acceptor#GO:0016773;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;carbohydrate kinase activity#GO:0019200;carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;ADP catabolic process#GO:0046032;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 carbohydrate kinase#PC00065;kinase#PC00137;transferase#PC00220 MONDO|Ensembl=ENSMODG00000021288.4|UniProtKB=F7GE15 F7GE15 MCCC1 PTHR18866:SF33 CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ligase#PC00142;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000047654.1|UniProtKB=A0A5F8G8X2 A0A5F8G8X2 SLC16A11 PTHR11360:SF80 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 11 monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 MONDO|Ensembl=ENSMODG00000001074.4|UniProtKB=F6YQF9 F6YQF9 MAPK7 PTHR24055:SF561 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 7 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 Parkinson disease#P00049>ERK#P01211;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;CCKR signaling map#P06959>MAPK7#P07021;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Interleukin signaling pathway#P00036>ERK#P00965;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Endothelin signaling pathway#P00019>ERK#P00566;EGF receptor signaling pathway#P00018>ERK1-2#P00543;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;Apoptosis signaling pathway#P00006>MAPK#P00269;FGF signaling pathway#P00021>ERK1-2#P00627;PDGF signaling pathway#P00047>ERK#P01143 MONDO|Ensembl=ENSMODG00000028056.2|UniProtKB=K7E5R5 K7E5R5 MDFIC2 PTHR15304:SF2 MYOD FAMILY INHIBITOR MYOD FAMILY INHIBITOR DOMAIN-CONTAINING PROTEIN 2 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;negative regulation of RNA biosynthetic process#GO:1902679;regulation of response to stimulus#GO:0048583;negative regulation of RNA metabolic process#GO:0051253;regulation of JNK cascade#GO:0046328;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000018451.2|UniProtKB=A0A5F8HAE3 A0A5F8HAE3 PTHR43184:SF11 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A1 carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605;phosphate transmembrane transporter activity#GO:0005315;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297 inorganic anion transport#GO:0015698;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;phosphate ion transport#GO:0006817;organophosphate ester transport#GO:0015748;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 transporter#PC00227 MONDO|Ensembl=ENSMODG00000002552.4|UniProtKB=F7GFD9 F7GFD9 SHC4 PTHR10337:SF12 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007420.4|UniProtKB=F7EE59 F7EE59 PNLDC1 PTHR15092:SF50 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 POLY(A)-SPECIFIC RIBONUCLEASE PNLDC1 hydrolase activity#GO:0016787;RNA binding#GO:0003723;nuclease activity#GO:0004518;nucleic acid binding#GO:0003676;binding#GO:0005488;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788 mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;RNA 3'-end processing#GO:0031123;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulatory ncRNA-mediated gene silencing#GO:0031047 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000001571.4|UniProtKB=F7BX21 F7BX21 PTHR10957:SF3 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1-B-RELATED cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000010631.4|UniProtKB=F7DP18 F7DP18 KIRREL1 PTHR11640:SF14 NEPHRIN KIN OF IRRE-LIKE PROTEIN 1 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000009253.3|UniProtKB=A0A5F8GD34 A0A5F8GD34 PAQR5 PTHR20855:SF38 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR GAMMA molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040668.1|UniProtKB=F7EIB5 F7EIB5 LOC107649435 PTHR48018:SF106 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M11 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000042417.1|UniProtKB=A0A5F8GT94 A0A5F8GT94 PTHR33968:SF1 PROTEIN PET100 HOMOLOG, MITOCHONDRIAL PROTEIN PET100 HOMOLOG, MITOCHONDRIAL mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;chaperone-mediated protein complex assembly#GO:0051131 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000007202.2|UniProtKB=F6WTY2 F6WTY2 LIPT2 PTHR10993:SF7 OCTANOYLTRANSFERASE OCTANOYL-[ACYL-CARRIER-PROTEIN]:PROTEIN N-OCTANOYLTRANSFERASE LIPT2, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 transferase#PC00220 Lipoate_biosynthesis#P02750>Lipoyl-protein ligase#P03003 MONDO|Ensembl=ENSMODG00000008623.4|UniProtKB=F6PGZ8 F6PGZ8 FRMD3 PTHR23280:SF8 4.1 G PROTEIN FERM DOMAIN-CONTAINING PROTEIN 3 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000024384.2|UniProtKB=F6Z4S3 F6Z4S3 LOC100019929 PTHR48002:SF134 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000505.3|UniProtKB=A0A5F8G3D9 A0A5F8G3D9 LMOD1 PTHR10901:SF5 TROPOMODULIN LEIOMODIN-1 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;actomyosin structure organization#GO:0031032;cell development#GO:0048468;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;system process#GO:0003008;actin filament organization#GO:0007015;muscle contraction#GO:0006936;developmental process#GO:0032502;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;contractile muscle fiber#GO:0043292;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000028492.2|UniProtKB=A0A5F8GG11 A0A5F8GG11 NME1 PTHR11349:SF69 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE A phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205 cellular process#GO:0009987;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793;nucleoside triphosphate biosynthetic process#GO:0009142;biosynthetic process#GO:0009058;nucleoside triphosphate metabolic process#GO:0009141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 kinase#PC00137;transferase#PC00220 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 MONDO|Ensembl=ENSMODG00000002817.4|UniProtKB=F7EJ26 F7EJ26 DNAH5 PTHR10676:SF344 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 5 cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;protein binding#GO:0005515;microtubule motor activity#GO:0003777;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;ATP-dependent activity#GO:0140657 outer dynein arm assembly#GO:0036158;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;organelle assembly#GO:0070925;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;cilium-dependent cell motility#GO:0060285 axonemal dynein complex#GO:0005858;dynein complex#GO:0030286;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;9+2 motile cilium#GO:0097729;cilium#GO:0005929;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;outer dynein arm#GO:0036157;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000015230.4|UniProtKB=F6V2T1 F6V2T1 MSH5 PTHR11361:SF20 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER MUTS PROTEIN HOMOLOG 5 DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;homologous chromosome pairing at meiosis#GO:0007129;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;DNA recombination#GO:0006310;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;meiosis I#GO:0007127;cell cycle process#GO:0022402;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;nucleobase-containing compound metabolic process#GO:0006139;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;reciprocal homologous recombination#GO:0140527;homologous recombination#GO:0035825;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000007417.4|UniProtKB=F7EE73 F7EE73 PTHR24377:SF710 IP01015P-RELATED ZINC FINGER PROTEIN 181-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000039748.1|UniProtKB=A0A5F8GQ95 A0A5F8GQ95 RPL37A PTHR48160:SF1 LARGE RIBOSOMAL SUBUNIT PROTEIN EL43 LARGE RIBOSOMAL SUBUNIT PROTEIN EL43 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000007871.4|UniProtKB=F7EB97 F7EB97 CTC1 PTHR14865:SF2 CST COMPLEX SUBUNIT CTC1 CST COMPLEX SUBUNIT CTC1 single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of DNA metabolic process#GO:0051054;cellular component organization#GO:0016043;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;telomere organization#GO:0032200;regulation of DNA replication#GO:0006275;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA replication#GO:0045740;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;telomere maintenance via telomere lengthening#GO:0010833;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;nuclear telomere cap complex#GO:0000783;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000001343.4|UniProtKB=F7FWB2 F7FWB2 NDUFA11 PTHR21382:SF1 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000007595.4|UniProtKB=F7CPA6 F7CPA6 PREX2 PTHR22829:SF1 DEP DOMAIN PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE-DEPENDENT RAC EXCHANGER 2 PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;molecular function activator activity#GO:0140677;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;enzyme activator activity#GO:0008047;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;kinase inhibitor activity#GO:0019210 cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;signal transduction#GO:0007165;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000016295.4|UniProtKB=F7AU20 F7AU20 KCNB1 PTHR11537:SF63 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY B MEMBER 1 transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;metal ion transport#GO:0030001;action potential#GO:0001508;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085 plasma membrane protein complex#GO:0098797;cell body#GO:0044297;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;axon#GO:0030424;leading edge membrane#GO:0031256;dendritic tree#GO:0097447;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495;cell projection membrane#GO:0031253;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;synaptic membrane#GO:0097060;neuron projection membrane#GO:0032589;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;cell junction#GO:0030054 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000004195.4|UniProtKB=A0A5F8G5Q2 A0A5F8G5Q2 GPATCH2 PTHR14195:SF4 G PATCH DOMAIN CONTAINING PROTEIN 2 G PATCH DOMAIN-CONTAINING PROTEIN 2 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000043272.1|UniProtKB=A0A5F8G6P5 A0A5F8G6P5 LOC100616824 PTHR24377:SF217 IP01015P-RELATED ZINC FINGER PROTEIN 286A-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016484.4|UniProtKB=A0A5F8GW77 A0A5F8GW77 PTHR21346:SF5 FUN14 DOMAIN CONTAINING FUN14 DOMAIN-CONTAINING PROTEIN 2 process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056;cellular process#GO:0009987;autophagy#GO:0006914;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152 intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000012174.4|UniProtKB=F7CY68 F7CY68 MLXIP PTHR15741:SF23 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR MLX-INTERACTING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000000502.5|UniProtKB=F6TU52 F6TU52 HOXA2 PTHR45664:SF3 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-A2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000004415.4|UniProtKB=F6SD46 F6SD46 PLCB1 PTHR10336:SF12 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-1 protein binding#GO:0005515;hydrolase activity#GO:0016787;lipase activity#GO:0016298;binding#GO:0005488;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;calmodulin binding#GO:0005516;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;transport#GO:0006810;system process#GO:0003008;establishment of localization#GO:0051234;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;cognition#GO:0050890;intracellular signal transduction#GO:0035556;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;signal transduction#GO:0007165;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;glycerophospholipid metabolic process#GO:0006650;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;calcium ion transmembrane transport#GO:0070588;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nuclear body#GO:0016604;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear speck#GO:0016607;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 hydrolase#PC00121;phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143 Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;CCKR signaling map#P06959>PLC_beta#P07110;Gonadotropin-releasing hormone receptor pathway#P06664>PLCbeta#P06705;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;2-arachidonoylglycerol biosynthesis#P05726>PLC#P05738;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Wnt signaling pathway#P00057>Phospholipase C#P01443;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PLC#P05933;Endogenous cannabinoid signaling#P05730>PLC#P05746;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Endothelin signaling pathway#P00019>PLCbeta#P00591;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744 MONDO|Ensembl=ENSMODG00000014124.5|UniProtKB=A0A5F8GN94 A0A5F8GN94 CALD1 PTHR18949:SF0 CALDESMON CALDESMON protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;myosin binding#GO:0017022 cellular component assembly#GO:0022607;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000004263.3|UniProtKB=F6TVI9 F6TVI9 N4BP3 PTHR32274:SF1 NEDD4-BINDING PROTEIN 3 NEDD4-BINDING PROTEIN 3 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000005826.4|UniProtKB=F6U1W3 F6U1W3 RBFOX1 PTHR15597:SF52 ATAXIN 2-BINDING PROTEIN 1-RELATED RNA BINDING PROTEIN FOX-1 HOMOLOG 1 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;nervous system development#GO:0007399;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000013363.4|UniProtKB=A0A5F8H353 A0A5F8H353 BCL9L PTHR15185:SF3 BCL9 B-CELL CLL_LYMPHOMA 9-LIKE PROTEIN binding#GO:0005488;protein binding#GO:0005515;beta-catenin binding#GO:0008013 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of RNA biosynthetic process#GO:1902680;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000021541.4|UniProtKB=F7DZQ4 F7DZQ4 EML2 PTHR13720:SF50 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 2 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000002618.4|UniProtKB=F7G4K8 F7G4K8 ST6GAL2 PTHR46059:SF3 BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 2 sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;cellular process#GO:0009987;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000013630.4|UniProtKB=F6UVW9 F6UVW9 PTHR15446:SF2 UROPLAKIN III UROPLAKIN-3B-LIKE PROTEIN 1-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000017022.4|UniProtKB=F6Y0X6 F6Y0X6 PTHR10166:SF6 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-1 gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;sarcolemma#GO:0042383;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;calcium channel complex#GO:0034704;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>Ca2+ channel#P01081 MONDO|Ensembl=ENSMODG00000014035.4|UniProtKB=F6UQK5 F6UQK5 P4HA2 PTHR10869:SF244 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2 oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000046418.1|UniProtKB=A0A5F8G324 A0A5F8G324 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000039800.1|UniProtKB=A0A5F8GXR1 A0A5F8GXR1 PTHR23415:SF29 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT-RELATED protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 mitotic cell cycle process#GO:1903047;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic cell cycle phase transition#GO:0044772;cell cycle#GO:0007049 intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000009022.4|UniProtKB=F7B334 F7B334 THAP10 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000018770.4|UniProtKB=F7AE38 F7AE38 OTUD7B PTHR13367:SF8 UBIQUITIN THIOESTERASE OTU DOMAIN-CONTAINING PROTEIN 7B peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;polyubiquitin modification-dependent protein binding#GO:0031593;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;protein binding#GO:0005515;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;binding#GO:0005488;modification-dependent protein binding#GO:0140030 negative regulation of signaling#GO:0023057;protein modification by small protein conjugation or removal#GO:0070647;regulation of intracellular signal transduction#GO:1902531;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of canonical NF-kappaB signal transduction#GO:0043122;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;post-translational protein modification#GO:0043687 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000023761.2|UniProtKB=F6SWZ2 F6SWZ2 PTHR24028:SF234 CADHERIN-87A PROTOCADHERIN GAMMA-A7 cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000002161.4|UniProtKB=F6YEU7 F6YEU7 TBC1D16 PTHR22957:SF547 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 16 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000021156.4|UniProtKB=F6QBQ6 F6QBQ6 GLS2 PTHR12544:SF33 GLUTAMINASE GLUTAMINASE LIVER ISOFORM, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000003126.4|UniProtKB=F6W869 F6W869 F5 PTHR24543:SF302 MULTICOPPER OXIDASE-RELATED COAGULATION FACTOR V coagulation#GO:0050817;response to wounding#GO:0009611;hemostasis#GO:0007599;response to stress#GO:0006950;biological regulation#GO:0065007;blood circulation#GO:0008015;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;regulation of body fluid levels#GO:0050878;circulatory system process#GO:0003013;system process#GO:0003008;regulation of biological quality#GO:0065008;wound healing#GO:0042060;blood coagulation#GO:0007596 secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141 oxidoreductase#PC00176 Blood coagulation#P00011>FVa#P00435;Blood coagulation#P00011>FV#P00432 MONDO|Ensembl=ENSMODG00000008125.4|UniProtKB=F7FV16 F7FV16 SH3GLB1 PTHR14167:SF52 SH3 DOMAIN-CONTAINING ENDOPHILIN-B1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000016882.3|UniProtKB=F6Y138 F6Y138 RPUSD1 PTHR21600:SF94 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE RPUSD1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000002343.3|UniProtKB=A0A5F8HBX6 A0A5F8HBX6 PTHR11792:SF22 ARRESTIN BETA-ARRESTIN-1 signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 regulation of MAPK cascade#GO:0043408;import into cell#GO:0098657;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;receptor internalization#GO:0031623;negative regulation of signal transduction#GO:0009968;regulation of ERK1 and ERK2 cascade#GO:0070372;vesicle-mediated transport#GO:0016192;nervous system process#GO:0050877;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;endocytosis#GO:0006897;negative regulation of Notch signaling pathway#GO:0045746;positive regulation of intracellular signal transduction#GO:1902533;regulation of G protein-coupled receptor signaling pathway#GO:0008277;transport#GO:0006810;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;system process#GO:0003008;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;regulation of Notch signaling pathway#GO:0008593;localization#GO:0051179;positive regulation of signal transduction#GO:0009967;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>beta-arrestin#P00723;Wnt signaling pathway#P00057>beta-arrestin#P01456;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>beta-arrestin#P00880;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>beta-ARR1#P05925 MONDO|Ensembl=ENSMODG00000003248.4|UniProtKB=F6THA5 F6THA5 SLC25A26 PTHR45667:SF9 S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN MITOCHONDRIAL S-ADENOSYLMETHIONINE CARRIER PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 mitochondrial carrier protein#PC00158 MONDO|Ensembl=ENSMODG00000009428.3|UniProtKB=F7BKU2 F7BKU2 VAX1 PTHR24339:SF32 HOMEOBOX PROTEIN EMX-RELATED VENTRAL ANTERIOR HOMEOBOX 1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;head development#GO:0060322;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000036828.1|UniProtKB=A0A5F8HAZ5 A0A5F8HAZ5 PTHR12253:SF17 RH14732P PROTEIN PROCA1 MONDO|Ensembl=ENSMODG00000025744.2|UniProtKB=F6T1V6 F6T1V6 SNCB PTHR13820:SF4 SYNUCLEIN BETA-SYNUCLEIN cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;copper ion binding#GO:0005507;binding#GO:0005488;small molecule binding#GO:0036094 cell communication#GO:0007154;localization#GO:0051179;cellular localization#GO:0051641;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;endocytosis#GO:0006897;signaling#GO:0023052;synaptic vesicle endocytosis#GO:0048488;chemical synaptic transmission#GO:0007268;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 axon terminus#GO:0043679;cell junction#GO:0030054;presynapse#GO:0098793;neuron projection#GO:0043005;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cell body#GO:0044297;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;neuron projection terminus#GO:0044306;cellular anatomical structure#GO:0110165;synapse#GO:0045202 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 Parkinson disease#P00049>beta-Synuclein#P01217 MONDO|Ensembl=ENSMODG00000027488.2|UniProtKB=K7E0S6 K7E0S6 PTHR11480:SF36 SAPOSIN-RELATED PROSAPOSIN-RELATED signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;cell communication#GO:0007154;regulation of lipid metabolic process#GO:0019216;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000045616.1|UniProtKB=A0A5F8GZP8 A0A5F8GZP8 PTHR23304:SF194 SPOT2-RELATED SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000047419.1|UniProtKB=F6X5U6 F6X5U6 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008236.4|UniProtKB=F6ZXU0 F6ZXU0 METTL5 PTHR23290:SF0 RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5 RRNA N(6)-ADENOSINE-METHYLTRANSFERASE METTL5 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a rRNA#GO:0140102;rRNA (adenine) methyltransferase activity#GO:0016433 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;ribosome biogenesis#GO:0042254;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;rRNA methylation#GO:0031167;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152 MONDO|Ensembl=ENSMODG00000018047.4|UniProtKB=F7GEN6 F7GEN6 IFT57 PTHR16011:SF0 IFT57/HIPPI INTRAFLAGELLAR TRANSPORT PROTEIN 57 HOMOLOG organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;localization#GO:0051179;non-motile cilium assembly#GO:1905515;cellular localization#GO:0051641;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;Golgi apparatus#GO:0005794;cytoskeleton#GO:0005856;intraciliary transport particle B#GO:0030992;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929 structural protein#PC00211 Huntington disease#P00029>Hip-12#P00763;Huntington disease#P00029>Hippi#P00794 MONDO|Ensembl=ENSMODG00000019853.3|UniProtKB=H9H7I8 H9H7I8 ATP5F1B PTHR15184:SF88 ATP SYNTHASE ATP SYNTHASE F(1) COMPLEX SUBUNIT BETA, MITOCHONDRIAL monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261 purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ATP biosynthetic process#GO:0006754;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;oxidative phosphorylation#GO:0006119;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206 membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;proton-transporting ATP synthase complex#GO:0045259;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ATP synthase#PC00002 ATP synthesis#P02721>F1 beta#P02794 MONDO|Ensembl=ENSMODG00000006369.4|UniProtKB=F7GCU3 F7GCU3 ABCD4 PTHR11384:SF59 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER LYSOSOMAL COBALAMIN TRANSPORTER ABCD4 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626 primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000037522.1|UniProtKB=A0A5F8G6J1 A0A5F8G6J1 LOC103099050 PTHR20842:SF0 PROTEASE S51 ALPHA-ASPARTYL DIPEPTIDASE DIPEPTIDASE E protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000050380.1|UniProtKB=K7E5P8 K7E5P8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010382.4|UniProtKB=F7AVB4 F7AVB4 PTHR21502:SF7 ZINC FINGER PROTEIN DZIP1 RAB-INTERACTING LYSOSOMAL PROTEIN small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 cellular process#GO:0009987;early endosome to late endosome transport#GO:0045022;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179 intracellular organelle#GO:0043229;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;lytic vacuole#GO:0000323;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;vacuole#GO:0005773;cytoplasm#GO:0005737 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000051444.1|UniProtKB=A0A5F8GZ25 A0A5F8GZ25 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000051032.1|UniProtKB=A0A5F8G768 A0A5F8G768 TREM2 PTHR16423:SF11 TREM-LIKE TRANSCRIPT PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 MONDO|Ensembl=ENSMODG00000047395.1|UniProtKB=K7E242 K7E242 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000017465.2|UniProtKB=F6Z581 F6Z581 PTHR28541:SF1 DDB1- AND CUL4-ASSOCIATED FACTOR 15 DDB1- AND CUL4-ASSOCIATED FACTOR 15 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000000662.4|UniProtKB=A0A5F8H9A1 A0A5F8H9A1 PPP1R12B PTHR24179:SF18 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12B enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666 A band#GO:0031672;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;I band#GO:0031674;sarcomere#GO:0030017;membraneless organelle#GO:0043228 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000004476.4|UniProtKB=F6VRJ6 F6VRJ6 NUB1 PTHR12948:SF3 NEDD8 ULTIMATE BUSTER-1 BS4 PROTEIN NEDD8 ULTIMATE BUSTER 1 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of catabolic process#GO:0009894;regulation of protein catabolic process#GO:0042176 MONDO|Ensembl=ENSMODG00000028517.2|UniProtKB=K7E420 K7E420 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000025332.4|UniProtKB=F7AP75 F7AP75 CHST7 PTHR10704:SF5 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 7 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;amino sugar metabolic process#GO:0006040;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;chondroitin sulfate proteoglycan metabolic process#GO:0050654;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000041970.1|UniProtKB=A0A5F8HE13 A0A5F8HE13 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000017853.4|UniProtKB=F6Z7T0 F6Z7T0 TMEM62 PTHR14795:SF0 HELICASE RELATED TRANSMEMBRANE PROTEIN 62 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000041753.1|UniProtKB=A0A5F8H523 A0A5F8H523 LOC100021998 PTHR26450:SF425 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56A1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040730.1|UniProtKB=A0A5F8G5K8 A0A5F8G5K8 PTHR10041:SF10 COLIPASE LEUCINE-RICH COLIPASE-LIKE PROTEIN 1 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000023715.2|UniProtKB=F6VFD9 F6VFD9 SELENOW PTHR15124:SF18 SELENOPROTEIN W SELENOPROTEIN W cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000009742.4|UniProtKB=F6X9L0 F6X9L0 RBM45 PTHR10352:SF18 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G RNA BINDING MOTIF PROTEIN 45 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000001371.4|UniProtKB=F7FJL5 F7FJL5 RANBP3 PTHR23138:SF91 RAN BINDING PROTEIN RAN-BINDING PROTEIN 3 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein export from nucleus#GO:0006611;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein transport#GO:0015031;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010078.3|UniProtKB=F6XMW6 F6XMW6 SLC25A1 PTHR45788:SF4 SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED TRICARBOXYLATE TRANSPORT PROTEIN, MITOCHONDRIAL active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;citrate transmembrane transporter activity#GO:0015137 carboxylic acid transmembrane transport#GO:1905039;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;citrate transport#GO:0015746;tricarboxylic acid transport#GO:0006842;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227 MONDO|Ensembl=ENSMODG00000043844.1|UniProtKB=A0A5F8HCQ6 A0A5F8HCQ6 MAX PTHR10328:SF3 PROTEIN MAX MYC-ASSOCIATED FACTOR X PROTEIN MAX DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 Oxidative stress response#P00046>Max#P01133 MONDO|Ensembl=ENSMODG00000041924.1|UniProtKB=A0A5F8HFM3 A0A5F8HFM3 LOC100027674 PTHR23089:SF55 HISTIDINE TRIAD HIT PROTEIN ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 purine nucleotide catabolic process#GO:0006195;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 nucleotide phosphatase#PC00173 MONDO|Ensembl=ENSMODG00000018875.4|UniProtKB=F7DA93 F7DA93 POGZ PTHR24388:SF45 ZINC FINGER PROTEIN POGO TRANSPOSABLE ELEMENT WITH ZNF DOMAIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000039234.1|UniProtKB=A0A5F8HJF0 A0A5F8HJF0 PTHR12668:SF11 TRANSMEMBRANE PROTEIN 14, 15 TRANSMEMBRANE PROTEIN 14A mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000018137.4|UniProtKB=A0A5F8HF34 A0A5F8HF34 UFL1 PTHR31057:SF0 E3 UFM1-PROTEIN LIGASE 1 E3 UFM1-PROTEIN LIGASE 1 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;cellular response to stress#GO:0033554;process utilizing autophagic mechanism#GO:0061919;response to stress#GO:0006950;reticulophagy#GO:0061709;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;autophagy#GO:0006914;catabolic process#GO:0009056;response to stimulus#GO:0050896;macroautophagy#GO:0016236 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000003862.3|UniProtKB=F7DTZ6 F7DTZ6 PTHR11967:SF2 ALPHA-1-ACID GLYCOPROTEIN ALPHA-1-ACID GLYCOPROTEIN 1 acute inflammatory response#GO:0002526;defense response#GO:0006952;response to stimulus#GO:0050896;immune response#GO:0006955;inflammatory response#GO:0006954;immune system process#GO:0002376;response to stress#GO:0006950 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000041337.1|UniProtKB=A0A5F8H720 A0A5F8H720 LOC100018815 PTHR22776:SF107 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CHEMOKINE-LIKE FACTOR signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response#GO:0006955;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005897.4|UniProtKB=F7E2W1 F7E2W1 GAR1 PTHR23237:SF6 NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;binding#GO:0005488 gene expression#GO:0010467;telomere maintenance via telomere lengthening#GO:0010833;telomere maintenance via telomerase#GO:0007004;RNA processing#GO:0006396;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;rRNA modification#GO:0000154;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;RNA-templated DNA biosynthetic process#GO:0006278;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;pseudouridine synthesis#GO:0001522;macromolecule modification#GO:0043412;telomere organization#GO:0032200;rRNA processing#GO:0006364 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000028846.2|UniProtKB=K7E0X4 K7E0X4 LNP1 PTHR35667:SF1 LEUKEMIA NUP98 FUSION PARTNER 1 LEUKEMIA NUP98 FUSION PARTNER 1 MONDO|Ensembl=ENSMODG00000015941.3|UniProtKB=F6Z340 F6Z340 PPP1R10 PTHR46557:SF1 SERINE/THREONINE-PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 10-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 10 protein binding#GO:0005515;protein phosphatase binding#GO:0019903;binding#GO:0005488;phosphatase binding#GO:0019902;enzyme binding#GO:0019899 chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000044366.1|UniProtKB=A0A5F8G6I2 A0A5F8G6I2 PTHR23304:SF183 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000024313.2|UniProtKB=F7E1J3 F7E1J3 PTHR48018:SF132 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045608.1|UniProtKB=A0A5F8HJH4 A0A5F8HJH4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007702.3|UniProtKB=F7F9F6 F7F9F6 LOC103094093 PTHR48001:SF15 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004015.4|UniProtKB=F7D6Z7 F7D6Z7 F7 PTHR24278:SF26 COAGULATION FACTOR COAGULATION FACTOR VII catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 proteolysis#GO:0006508;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;wound healing#GO:0042060;hemostasis#GO:0007599;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;blood coagulation#GO:0007596;response to wounding#GO:0009611;response to stress#GO:0006950;coagulation#GO:0050817;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 Blood coagulation#P00011>FVII#P00454;Angiogenesis#P00005>FVIIa#P00201;Blood coagulation#P00011>FVIIa#P00447 MONDO|Ensembl=ENSMODG00000004277.3|UniProtKB=F6TEK9 F6TEK9 TMBIM6 PTHR23291:SF133 BAX INHIBITOR-RELATED BAX INHIBITOR 1 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;response to topologically incorrect protein#GO:0035966;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;negative regulation of apoptotic signaling pathway#GO:2001234;cellular response to topologically incorrect protein#GO:0035967;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of signaling#GO:0023057;cellular response to unfolded protein#GO:0034620;negative regulation of cell communication#GO:0010648;response to unfolded protein#GO:0006986;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;response to stress#GO:0006950;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 transporter#PC00227;ion channel#PC00133 Apoptosis signaling pathway#P00006>Bi1#P00277 MONDO|Ensembl=ENSMODG00000021208.4|UniProtKB=F7B223 F7B223 IRS1 PTHR10614:SF11 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 1 receptor tyrosine kinase binding#GO:0030971;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;binding#GO:0005488;kinase binding#GO:0019900;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591;protein binding#GO:0005515 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;insulin-like growth factor receptor signaling pathway#GO:0048009;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;response to hormone#GO:0009725;response to peptide hormone#GO:0043434;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 Gonadotropin-releasing hormone receptor pathway#P06664>IRS-1#P06825;PI3 kinase pathway#P00048>IRS#P01193;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899;CCKR signaling map#P06959>IRS1#P07106;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887;Interleukin signaling pathway#P00036>IRS1/2#P00980;Gonadotropin-releasing hormone receptor pathway#P06664>IRS#P06759 MONDO|Ensembl=ENSMODG00000009806.5|UniProtKB=F6SGQ9 F6SGQ9 PTHR36288:SF1 SIMILAR TO RIKEN CDNA A930018P22 SIMILAR TO HUMAN CHROMOSOME 11 OPEN READING FRAME 91 MONDO|Ensembl=ENSMODG00000001888.4|UniProtKB=F6WGJ9 F6WGJ9 NFKBIZ PTHR24124:SF5 ANKYRIN REPEAT FAMILY A NF-KAPPA-B INHIBITOR ZETA regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000003966.4|UniProtKB=F7FMT1 F7FMT1 KIF12 PTHR24115:SF418 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF12 cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000011411.5|UniProtKB=F6S5N8 F6S5N8 CCDC43 PTHR31684:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 43 COILED-COIL DOMAIN-CONTAINING PROTEIN 43 MONDO|Ensembl=ENSMODG00000008194.4|UniProtKB=A0A5F8HBR6 A0A5F8HBR6 VEZT PTHR15989:SF5 VEZATIN VEZATIN cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000001665.4|UniProtKB=F6SR81 F6SR81 EMC4 PTHR19315:SF9 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000041731.1|UniProtKB=A0A5F8G3W3 A0A5F8G3W3 PTHR23304:SF189 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000009982.4|UniProtKB=F6Y796 F6Y796 DSP PTHR23169:SF26 ENVOPLAKIN DESMOPLAKIN skin development#GO:0043588;cytoskeleton organization#GO:0007010;response to stress#GO:0006950;cell-cell adhesion#GO:0098609;response to wounding#GO:0009611;organelle organization#GO:0006996;cellular process#GO:0009987;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;intermediate filament cytoskeleton organization#GO:0045104;response to stimulus#GO:0050896;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;wound healing#GO:0042060;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intercalated disc#GO:0014704;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;cell-cell contact zone#GO:0044291;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054 intermediate filament binding protein#PC00130;intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000009167.3|UniProtKB=K7DZB7 K7DZB7 MTUS2 PTHR24200:SF14 TOUCAN, ISOFORM A MICROTUBULE-ASSOCIATED TUMOR SUPPRESSOR CANDIDATE 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000016564.4|UniProtKB=F7DN45 F7DN45 ANKRD22 PTHR47276:SF1 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 22 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 22 response to stimulus#GO:0050896;cell migration#GO:0016477;cell motility#GO:0048870;immune response#GO:0006955;cellular process#GO:0009987;response to stress#GO:0006950;response to wounding#GO:0009611;leukocyte migration#GO:0050900;immune system process#GO:0002376 MONDO|Ensembl=ENSMODG00000014554.4|UniProtKB=F7E8W9 F7E8W9 CPA4 PTHR11705:SF136 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A4 metallopeptidase activity#GO:0008237;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000051408.1|UniProtKB=A0A5F8HJI7 A0A5F8HJI7 PTHR21213:SF0 GEO09665P1-RELATED ZINC FINGER PROTEIN 706 MONDO|Ensembl=ENSMODG00000023611.2|UniProtKB=F7AZQ5 F7AZQ5 LOC100014303 PTHR26452:SF175 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000012344.4|UniProtKB=F7G6C6 F7G6C6 HOXB3 PTHR45664:SF11 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-B3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;skeletal system morphogenesis#GO:0048705;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;skeletal system development#GO:0001501;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;anterior/posterior pattern specification#GO:0009952;animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;embryo development#GO:0009790 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000021492.4|UniProtKB=A0A5F8GST5 A0A5F8GST5 GATA6 PTHR10071:SF23 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANSCRIPTION FACTOR GATA-6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;positive regulation of DNA-templated transcription#GO:0045893;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000043947.1|UniProtKB=A0A5F8G1P3 A0A5F8G1P3 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000050336.1|UniProtKB=A0A5F8GDU7 A0A5F8GDU7 PTHR10489:SF671 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 3 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375 response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;chemotaxis#GO:0006935;cell communication#GO:0007154;cell chemotaxis#GO:0060326;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;signaling#GO:0023052;locomotion#GO:0040011 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000015692.4|UniProtKB=F7E0S5 F7E0S5 PPP4C PTHR45619:SF8 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 4 CATALYTIC SUBUNIT phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 MONDO|Ensembl=ENSMODG00000043026.1|UniProtKB=F7FBV3 F7FBV3 PTHR26450:SF46 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51F1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000046619.1|UniProtKB=A0A5F8GNR4 A0A5F8GNR4 UBE2Z PTHR46116:SF26 (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME UBIQUITIN-CONJUGATING ENZYME E2 Z ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096 regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000020740.4|UniProtKB=F7AN44 F7AN44 UBA6 PTHR10953:SF186 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 6 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657 cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 MONDO|Ensembl=ENSMODG00000044474.1|UniProtKB=A0A5F8GKS2 A0A5F8GKS2 PTHR10353:SF68 GLYCOSYL HYDROLASE BETA-KLOTHO glucosidase activity#GO:0015926;beta-glucosidase activity#GO:0008422;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 metabolite interconversion enzyme#PC00262;glycosidase#PC00110;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000024155.2|UniProtKB=F6XXZ8 F6XXZ8 ZDHHC20 PTHR22883:SF417 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC20 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein targeting#GO:0006605;cellular component organization#GO:0016043;establishment of localization#GO:0051234;synaptic vesicle maturation#GO:0016188;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;protein targeting to membrane#GO:0006612;developmental process#GO:0032502;developmental maturation#GO:0021700;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000036840.1|UniProtKB=A0A5F8GG35 A0A5F8GG35 PTHR12817:SF3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;trans-Golgi network#GO:0005802;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;cis-Golgi network#GO:0005801;Golgi apparatus#GO:0005794;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000019843.4|UniProtKB=A0A5F8GE41 A0A5F8GE41 MMP11 PTHR10201:SF20 MATRIX METALLOPROTEINASE STROMELYSIN-3 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;extracellular structure organization#GO:0043062;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;cellular process#GO:0009987;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000024324.2|UniProtKB=F7DGE3 F7DGE3 LOC100023160 PTHR48018:SF44 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8J1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005267.4|UniProtKB=F7GGQ0 F7GGQ0 USP21 PTHR21646:SF6 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 21 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000015800.2|UniProtKB=F7FRZ9 F7FRZ9 SELENOI PTHR10414:SF47 ETHANOLAMINEPHOSPHOTRANSFERASE ETHANOLAMINEPHOSPHOTRANSFERASE 1 transferase#PC00220 MONDO|Ensembl=ENSMODG00000008533.4|UniProtKB=F7DHD1 F7DHD1 PDSS1 PTHR12001:SF89 GERANYLGERANYL PYROPHOSPHATE SYNTHASE ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS1 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;primary metabolic process#GO:0044238;ketone metabolic process#GO:0042180;isoprenoid metabolic process#GO:0006720;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;isoprenoid biosynthetic process#GO:0008299;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262 Cholesterol biosynthesis#P00014>Dimethylallyl trans-transferase#P00490 MONDO|Ensembl=ENSMODG00000011767.4|UniProtKB=F7CW94 F7CW94 STAT4 PTHR11801:SF19 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;defense response#GO:0006952;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cytokine-mediated signaling pathway#GO:0019221;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;response to hormone#GO:0009725;cell surface receptor signaling pathway via STAT#GO:0097696;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;response to oxygen-containing compound#GO:1901700;response to peptide#GO:1901652 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Interleukin signaling pathway#P00036>STAT#P00996;PDGF signaling pathway#P00047>STAT#P01173;EGF receptor signaling pathway#P00018>STAT#P00561;JAK/STAT signaling pathway#P00038>STAT#P01027 MONDO|Ensembl=ENSMODG00000015804.4|UniProtKB=F7FRY9 F7FRY9 LANCL1 PTHR12736:SF5 LANC-LIKE PROTEIN GLUTATHIONE S-TRANSFERASE LANCL1 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364 cellular process#GO:0009987;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to chemical#GO:0042221;regulation of response to stimulus#GO:0048583;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of cellular response to alcohol#GO:1905957;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;cellular detoxification#GO:1990748;regulation of abscisic acid-activated signaling pathway#GO:0009787;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of response to alcohol#GO:1901419 MONDO|Ensembl=ENSMODG00000037552.1|UniProtKB=A0A5F8GZK1 A0A5F8GZK1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000011585.5|UniProtKB=F6X999 F6X999 PRG4 PTHR22917:SF1 HEMOPEXIN DOMAIN-CONTAINING PROTEIN PROTEOGLYCAN 4 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 MONDO|Ensembl=ENSMODG00000002006.4|UniProtKB=A0A5F8HC13 A0A5F8HC13 ATXN3 PTHR14159:SF0 ATAXIN-3-RELATED ATAXIN-3-RELATED cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 negative regulation of biological process#GO:0048519;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;regulation of cellular response to stress#GO:0080135;regulation of protein metabolic process#GO:0051246;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of TORC1 signaling#GO:1904262;primary metabolic process#GO:0044238;regulation of response to endoplasmic reticulum stress#GO:1905897;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;negative regulation of TOR signaling#GO:0032007;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;regulation of ERAD pathway#GO:1904292;protein metabolic process#GO:0019538;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stress#GO:0080134;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of TORC1 signaling#GO:1903432 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000010160.4|UniProtKB=F7BU41 F7BU41 CADM3 PTHR45889:SF5 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 3 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 cell junction#GO:0030054;synaptic membrane#GO:0097060;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000001961.4|UniProtKB=F6V2E5 F6V2E5 PTHR24376:SF258 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 814 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008735.4|UniProtKB=F6PTE7 F6PTE7 ADAM10 PTHR45702:SF4 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 10 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;cell communication#GO:0007154;proteolysis#GO:0006508;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;Notch signaling pathway#GO:0007219;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;membrane protein ectodomain proteolysis#GO:0006509;biological regulation#GO:0065007;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;signal transduction#GO:0007165 synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202 protease#PC00190;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>TACE#P01105;Alzheimer disease-amyloid secretase pathway#P00003>ADAM10#P00108 MONDO|Ensembl=ENSMODG00000002582.4|UniProtKB=A0A5F8H071 A0A5F8H071 CEP152 PTHR10337:SF6 SHC TRANSFORMING PROTEIN CENTROSOMAL PROTEIN OF 152 KDA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization or biogenesis#GO:0071840;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;centriole replication#GO:0007099;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000015920.3|UniProtKB=F6ZR88 F6ZR88 BRICD5 PTHR16483:SF0 GASTROKINE 1 BRICHOS DOMAIN-CONTAINING PROTEIN 5 regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;biological regulation#GO:0065007;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000014747.4|UniProtKB=F6YN56 F6YN56 TAF1B PTHR31576:SF6 TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;core promoter sequence-specific DNA binding#GO:0001046;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;rRNA transcription#GO:0009303;transcription by RNA polymerase I#GO:0006360;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667 General transcription by RNA polymerase I#P00022>TAF-IB#P00650 MONDO|Ensembl=ENSMODG00000025382.1|UniProtKB=F6Z9R8 F6Z9R8 LOC100017394 PTHR23050:SF218 CALCIUM BINDING PROTEIN CENTRIN-1 metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 organelle assembly#GO:0070925;centriole replication#GO:0007099;microtubule cytoskeleton organization#GO:0000226;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization or biogenesis#GO:0071840;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000001970.2|UniProtKB=F6RIT0 F6RIT0 PTHR31841:SF1 PROTEIN FAM72A-RELATED PROTEIN FAM72A-RELATED cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000039268.1|UniProtKB=A0A5F8G736 A0A5F8G736 LOC100027712 PTHR26452:SF52 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000048756.1|UniProtKB=A0A5F8GM44 A0A5F8GM44 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000047664.1|UniProtKB=A0A5F8G338 A0A5F8G338 LOC130454040 PTHR13177:SF3 DEATH-ASSOCIATED PROTEIN 1 DEATH-ASSOCIATED PROTEIN 1 ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of macromolecule metabolic process#GO:0010605;apoptotic signaling pathway#GO:0097190;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of autophagy#GO:0010507;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;negative regulation of catabolic process#GO:0009895;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;signal transduction#GO:0007165;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;negative regulation of translation#GO:0017148 MONDO|Ensembl=ENSMODG00000043916.1|UniProtKB=A0A5F8H1D2 A0A5F8H1D2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001384.4|UniProtKB=F7GL73 F7GL73 ACTC1 PTHR11937:SF176 ACTIN ACTIN, ALPHA CARDIAC MUSCLE 1 protein binding#GO:0005515;structural molecule activity#GO:0005198;myosin binding#GO:0017022;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 cellular component organization#GO:0016043;heart process#GO:0003015;actin cytoskeleton organization#GO:0030036;actin-mediated cell contraction#GO:0070252;circulatory system process#GO:0003013;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;actin filament-based movement#GO:0030048;cellular process#GO:0009987;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;heart contraction#GO:0060047;system process#GO:0003008;actin filament organization#GO:0007015 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;contractile muscle fiber#GO:0043292;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;actin filament#GO:0005884;cytoskeleton#GO:0005856;sarcomere#GO:0030017;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470 MONDO|Ensembl=ENSMODG00000023038.2|UniProtKB=A0A5F8G4B0 A0A5F8G4B0 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011974.3|UniProtKB=F7BA11 F7BA11 CISH PTHR10155:SF9 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT CYTOKINE-INDUCIBLE SH2-CONTAINING PROTEIN binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;signaling#GO:0023052;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;negative regulation of response to stimulus#GO:0048585;response to chemical#GO:0042221;response to cytokine#GO:0034097;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 kinase modulator#PC00140 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879;Interferon-gamma signaling pathway#P00035>SOCS#P00956 MONDO|Ensembl=ENSMODG00000039353.1|UniProtKB=A0A5F8HFB3 A0A5F8HFB3 LRRTM2 PTHR24373:SF268 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE RICH REPEAT TRANSMEMBRANE NEURONAL 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024129.2|UniProtKB=F6XZN2 F6XZN2 PTHR24189:SF71 MYOTROPHIN ANKYRIN REPEAT DOMAIN 39 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000012834.3|UniProtKB=F7DCL3 F7DCL3 PTHR26453:SF585 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 976 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015176.4|UniProtKB=F7BWJ8 F7BWJ8 PXMP2 PTHR11266:SF134 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 PEROXISOMAL MEMBRANE PROTEIN 2 peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000041549.1|UniProtKB=A0A5F8HE43 A0A5F8HE43 PTHR24225:SF0 CHEMOTACTIC RECEPTOR N-FORMYL PEPTIDE RECEPTOR 2 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 immune response-activating signaling pathway#GO:0002757;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of immune response#GO:0050778;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;regulation of biological quality#GO:0065008;cell communication#GO:0007154;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of immune response#GO:0050776;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000014695.4|UniProtKB=F7DN26 F7DN26 KLHL10 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000047650.1|UniProtKB=A0A5F8GAN8 A0A5F8GAN8 PTHR11349:SF116 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE B phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;nucleoside triphosphate metabolic process#GO:0009141;cellular process#GO:0009987;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793;nucleoside triphosphate biosynthetic process#GO:0009142 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;kinase#PC00137 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 MONDO|Ensembl=ENSMODG00000043567.1|UniProtKB=A0A5F8HJ49 A0A5F8HJ49 PTHR11846:SF13 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE ISOZYME 2 catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;IMP metabolic process#GO:0046040;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890 MONDO|Ensembl=ENSMODG00000007808.4|UniProtKB=F6ZII0 F6ZII0 PSTK PTHR20873:SF0 L-SERYL-TRNA(SEC) KINASE L-SERYL-TRNA(SEC) KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;RNA binding#GO:0003723;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;binding#GO:0005488 MONDO|Ensembl=ENSMODG00000050323.1|UniProtKB=A0A5F8GNB1 A0A5F8GNB1 VN2R577 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000028414.2|UniProtKB=K7DZK7 K7DZK7 PTHR42985:SF10 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 1 metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293 carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;fatty acid transport#GO:0015908;monoatomic ion transport#GO:0006811;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;lipid transport#GO:0006869;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000009814.4|UniProtKB=F7BDY3 F7BDY3 STOML1 PTHR10264:SF130 BAND 7 PROTEIN-RELATED STOMATIN-LIKE PROTEIN 1 molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;transporter regulator activity#GO:0141108 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000024800.1|UniProtKB=F7FNX9 F7FNX9 LRRN2 PTHR24373:SF162 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT NEURONAL PROTEIN 2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028789.2|UniProtKB=K7E4L6 K7E4L6 ARMH2 PTHR37679:SF1 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 2 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000012473.4|UniProtKB=F6Q472 F6Q472 LRRC46 PTHR45973:SF9 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 46 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000025003.1|UniProtKB=F6TCQ6 F6TCQ6 LOC100018978 PTHR48168:SF1 RNA GUANINE-7 METHYLTRANSFERASE-ACTIVATING SUBUNIT-LIKE (PSEUDOGENE)-RELATED RNA GUANINE-N7 METHYLTRANSFERASE ACTIVATING SUBUNIT-RELATED enzyme regulator activity#GO:0030234;RNA binding#GO:0003723;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleic acid binding#GO:0003676;binding#GO:0005488;enzyme activator activity#GO:0008047 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000024478.2|UniProtKB=F7GFG4 F7GFG4 TMEM100 PTHR16100:SF5 PHOSPHOINOSITIDE-INTERACTING PROTEIN FAMILY MEMBER TRANSMEMBRANE PROTEIN 100 regulation of system process#GO:0044057;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000011098.4|UniProtKB=F7DL45 F7DL45 LACTB PTHR46520:SF1 SERINE BETA-LACTAMASE-LIKE PROTEIN LACTB, MITOCHONDRIAL SERINE BETA-LACTAMASE-LIKE PROTEIN LACTB, MITOCHONDRIAL catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 metabolic process#GO:0008152;proteolysis#GO:0006508;regulation of lipid metabolic process#GO:0019216;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;primary metabolic process#GO:0044238;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000005363.4|UniProtKB=A0A5F8HDP6 A0A5F8HDP6 GRIN2A PTHR18966:SF407 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2A signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;voltage-gated channel activity#GO:0022832;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943 regulation of membrane potential#GO:0042391;cell surface receptor signaling pathway#GO:0007166;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;synaptic signaling#GO:0099536;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of signaling#GO:0023056;regulation of biological quality#GO:0065008;positive regulation of synaptic transmission#GO:0050806;regulation of signaling#GO:0023051;nervous system process#GO:0050877;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;system process#GO:0003008;regulation of synaptic plasticity#GO:0048167;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;modulation of chemical synaptic transmission#GO:0050804;chemical synaptic transmission, postsynaptic#GO:0099565;regulation of cell communication#GO:0010646;chemical synaptic transmission#GO:0007268;regulation of postsynaptic membrane potential#GO:0060078;cellular response to stimulus#GO:0051716 synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;cell junction#GO:0030054;transporter complex#GO:1990351;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;protein-containing complex#GO:0032991;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>NR2C#P01006;Ionotropic glutamate receptor pathway#P00037>NR2B#P01007;Ionotropic glutamate receptor pathway#P00037>NR2A#P01008;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Huntington disease#P00029>NMDA receptor#P00778;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039 MONDO|Ensembl=ENSMODG00000044302.1|UniProtKB=A0A5F8GGF3 A0A5F8GGF3 DEGS2 PTHR12879:SF21 SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 SPHINGOLIPID DELTA(4)-DESATURASE_C4-MONOOXYGENASE DES2 catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 oxidoreductase#PC00176;hydroxylase#PC00122 MONDO|Ensembl=ENSMODG00000009912.4|UniProtKB=F6R9P0 F6R9P0 ABTB2 PTHR46071:SF3 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 2 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006330.4|UniProtKB=F7AGV5 F7AGV5 MAP2K6 PTHR48013:SF12 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 6 phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>MKK3,6#P00540;Ras Pathway#P04393>MKK3/6#P04568;Gonadotropin-releasing hormone receptor pathway#P06664>MKK3/6#P06805;FGF signaling pathway#P00021>MKK3,6#P00625;CCKR signaling map#P06959>MAP2K6#P07233;Oxidative stress response#P00046>MKK3/6#P01121;p38 MAPK pathway#P05918>MKK6#P06032 MONDO|Ensembl=ENSMODG00000018064.4|UniProtKB=F7G490 F7G490 NCAPD2 PTHR14222:SF2 CONDENSIN CONDENSIN COMPLEX SUBUNIT 1 binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 organelle fission#GO:0048285;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;nuclear division#GO:0000280;sexual reproduction#GO:0019953;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;chromosome segregation#GO:0007059;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987 condensin complex#GO:0000796;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000047380.1|UniProtKB=A0A5F8GE80 A0A5F8GE80 MEMO1 PTHR11060:SF0 PROTEIN MEMO1 PROTEIN MEMO1 MONDO|Ensembl=ENSMODG00000045196.1|UniProtKB=A0A5F8HIQ9 A0A5F8HIQ9 LOC100023083 PTHR26450:SF138 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013124.4|UniProtKB=A0A5F8GN11 A0A5F8GN11 YY1 PTHR14003:SF33 TRANSCRIPTIONAL REPRESSOR PROTEIN YY TRANSCRIPTIONAL REPRESSOR PROTEIN YY1-LIKE cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cell development#GO:0048468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;PcG protein complex#GO:0031519;chromatin#GO:0000785;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005954.2|UniProtKB=A0A5F8G3U8 A0A5F8G3U8 QTRT1 PTHR43530:SF1 QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1 QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1 glycosyltransferase activity#GO:0016757;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;pentosyltransferase activity#GO:0016763 RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000006643.4|UniProtKB=F7G438 F7G438 MIER2 PTHR10865:SF27 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN MESODERM INDUCTION EARLY RESPONSE PROTEIN 2 transcription coregulator activity#GO:0003712;binding#GO:0005488;transcription corepressor activity#GO:0003714;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;protein binding#GO:0005515;histone deacetylase binding#GO:0042826 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000012943.3|UniProtKB=F7G1K7 F7G1K7 GNAQ PTHR10218:SF329 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 response to oxygen-containing compound#GO:1901700;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;glutamate receptor signaling pathway#GO:0007215;response to nitrogen compound#GO:1901698;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of biological process#GO:0050789;action potential#GO:0001508;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell surface receptor signaling pathway#GO:0007166;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of membrane potential#GO:0042391;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;G protein-coupled dopamine receptor signaling pathway#GO:0007212;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699 cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165 G-protein#PC00020;heterotrimeric G-protein#PC00117 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Endothelin signaling pathway#P00019>Gq#P00586;Gonadotropin-releasing hormone receptor pathway#P06664>gnaq/11#P06841;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Wnt signaling pathway#P00057>Galpha#P01451;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gqalpha#P05927;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057 MONDO|Ensembl=ENSMODG00000041225.1|UniProtKB=F6V7H0 F6V7H0 monDomV1R1265 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014231.4|UniProtKB=F6T9H2 F6T9H2 PTHR11818:SF50 BETA/GAMMA CRYSTALLIN BETA_GAMMA CRYSTALLIN DOMAIN-CONTAINING PROTEIN 2 structural molecule activity#GO:0005198 sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423;system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000028386.2|UniProtKB=K7E566 K7E566 PTHR35442:SF1 TRANSMEMBRANE PROTEIN 249 CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT THETA MONDO|Ensembl=ENSMODG00000013737.5|UniProtKB=F6X8D4 F6X8D4 PTHR47606:SF1 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY G MEMBER 2 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY G MEMBER 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009756.4|UniProtKB=F6TFJ3 F6TFJ3 LOC100025472 PTHR24056:SF538 CELL DIVISION PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE PRP4 HOMOLOG protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000021484.3|UniProtKB=A0A5F8H6U5 A0A5F8H6U5 ROCK1 PTHR22988:SF33 MYOTONIC DYSTROPHY S/T KINASE-RELATED RHO-ASSOCIATED PROTEIN KINASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell division#GO:0051301;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cell junction assembly#GO:1901888;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cortical actin cytoskeleton organization#GO:0030866;anatomical structure development#GO:0048856;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;Rho protein signal transduction#GO:0007266;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;intracellular signaling cassette#GO:0141124;embryo development#GO:0009790;regulation of actin cytoskeleton organization#GO:0032956;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 Cytoskeletal regulation by Rho GTPase#P00016>ROCK#P00519;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>ROCK#P00881;CCKR signaling map#P06959>ROCK1#P07033 MONDO|Ensembl=ENSMODG00000019920.4|UniProtKB=F6VP01 F6VP01 AGBL2 PTHR12756:SF41 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 2 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;tubulin binding#GO:0015631;metalloexopeptidase activity#GO:0008235;cytoskeletal protein binding#GO:0008092;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;protein binding#GO:0005515;carboxypeptidase activity#GO:0004180;binding#GO:0005488;metallopeptidase activity#GO:0008237 centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000024954.1|UniProtKB=F6UTM1 F6UTM1 TLR2 PTHR24365:SF17 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 2 binding#GO:0005488;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;lipid binding#GO:0008289 regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;regulation of innate immune response#GO:0045088;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;toll-like receptor signaling pathway#GO:0002224;immune system process#GO:0002376;regulation of response to external stimulus#GO:0032101;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR2,4,7#P01351;Toll receptor signaling pathway#P00054>TLR1,2,6#P01380;Toll receptor signaling pathway#P00054>TLR#P01346 MONDO|Ensembl=ENSMODG00000049946.1|UniProtKB=A0A5F8H6X2 A0A5F8H6X2 MINDY4B PTHR12473:SF18 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4B hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;deubiquitinase activity#GO:0101005 MONDO|Ensembl=ENSMODG00000029830.2|UniProtKB=A0A5F8H5I9 A0A5F8H5I9 POU2AF3 PTHR36689:SF1 COLORECTAL CANCER-ASSOCIATED PROTEIN 2 POU CLASS 2 HOMEOBOX ASSOCIATING FACTOR 3 MONDO|Ensembl=ENSMODG00000019758.4|UniProtKB=A0A5F8H383 A0A5F8H383 GOLGA1 PTHR23157:SF24 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GOLGIN SUBFAMILY A MEMBER 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000008997.2|UniProtKB=F7BQ80 F7BQ80 UBL4A PTHR46555:SF1 UBIQUITIN-LIKE PROTEIN 4A UBIQUITIN-LIKE PROTEIN 4A MONDO|Ensembl=ENSMODG00000016609.3|UniProtKB=F6ZCB0 F6ZCB0 SNRNP25 PTHR14942:SF21 U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000012146.4|UniProtKB=F7CZ01 F7CZ01 PTHR11769:SF23 HYALURONIDASE HYALURONIDASE-1 catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;glycosaminoglycan catabolic process#GO:0006027 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000004315.5|UniProtKB=F6X6Z7 F6X6Z7 RRP12 PTHR21576:SF2 UNCHARACTERIZED NODULIN-LIKE PROTEIN RRP12-LIKE PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000009763.3|UniProtKB=F6WT32 F6WT32 HS1BP3 PTHR14431:SF1 HCLS1-BINDING PROTEIN 3 HCLS1-BINDING PROTEIN 3 MONDO|Ensembl=ENSMODG00000051587.1|UniProtKB=A0A5F8GWB2 A0A5F8GWB2 LOC100010631 PTHR26453:SF161 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T29-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011808.4|UniProtKB=F7CBD2 F7CBD2 SYTL4 PTHR45716:SF4 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 4 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;exocytosis#GO:0006887;transport#GO:0006810;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987 secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000006871.4|UniProtKB=F6PX15 F6PX15 CPQ PTHR12053:SF6 PROTEASE FAMILY M28 PLASMA GLUTAMATE CARBOXYPEPTIDASE-RELATED CARBOXYPEPTIDASE Q peptidase activity#GO:0008233;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 regulation of biological quality#GO:0065008;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;biological regulation#GO:0065007;catabolic process#GO:0009056;hormone metabolic process#GO:0042445;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;phenol-containing compound metabolic process#GO:0018958;peptide catabolic process#GO:0043171;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000001293.3|UniProtKB=F7C083 F7C083 CDIN1 PTHR31661:SF2 SIMILAR TO CDNA SEQUENCE BC052040 CDAN1-INTERACTING NUCLEASE 1 anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;erythrocyte differentiation#GO:0030218;multicellular organismal-level homeostasis#GO:0048871;immune system process#GO:0002376;developmental process#GO:0032502;homeostasis of number of cells#GO:0048872;multicellular organismal process#GO:0032501;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;cell development#GO:0048468;hemopoiesis#GO:0030097;homeostatic process#GO:0042592;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000002069.3|UniProtKB=F6UZZ3 F6UZZ3 RBP3 PTHR11261:SF3 INTERPHOTORECEPTOR RETINOID-BINDING PROTEIN RETINOL-BINDING PROTEIN 3 binding#GO:0005488;small molecule binding#GO:0036094;alcohol binding#GO:0043178;lipid binding#GO:0008289 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 MONDO|Ensembl=ENSMODG00000008121.4|UniProtKB=F7FV33 F7FV33 PTHR11254:SF282 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE NEDD4 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106 ubiquitin-dependent protein catabolic process#GO:0006511;neurogenesis#GO:0022008;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;regulation of plasma membrane bounded cell projection organization#GO:0120035;macromolecule metabolic process#GO:0043170;transport#GO:0006810;developmental process#GO:0032502;regulation of cell projection organization#GO:0031344;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;system development#GO:0048731;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;localization#GO:0051179;synapse organization#GO:0050808;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of dendrite development#GO:0050773;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of dendrite morphogenesis#GO:0048814;neuromuscular junction development#GO:0007528;import into cell#GO:0098657;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nervous system development#GO:0007399;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;neuron projection development#GO:0031175;receptor internalization#GO:0031623;neuron development#GO:0048666;regulation of biological quality#GO:0065008;regulation of synapse organization#GO:0050807;modification-dependent macromolecule catabolic process#GO:0043632;generation of neurons#GO:0048699;protein catabolic process#GO:0030163;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;endocytosis#GO:0006897;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490 MONDO|Ensembl=ENSMODG00000004494.4|UniProtKB=F6VQR5 F6VQR5 MVK PTHR43290:SF4 MEVALONATE KINASE MEVALONATE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cholesterol biosynthetic process#GO:0006695;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;nucleobase-containing small molecule metabolic process#GO:0055086;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;isoprenoid biosynthetic process#GO:0008299;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;secondary alcohol biosynthetic process#GO:1902653;acyl-CoA metabolic process#GO:0006637;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;nucleoside phosphate metabolic process#GO:0006753;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;isoprenoid metabolic process#GO:0006720;organophosphate biosynthetic process#GO:0090407;acetyl-CoA metabolic process#GO:0006084 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 carbohydrate kinase#PC00065 Cholesterol biosynthesis#P00014>Mevalonate kinase#P00492 MONDO|Ensembl=ENSMODG00000003486.4|UniProtKB=F7CSQ1 F7CSQ1 ZAP70 PTHR24418:SF369 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ZAP-70 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 T cell activation#P00053>ZAP-70#P01308 MONDO|Ensembl=ENSMODG00000018353.4|UniProtKB=F6PQI2 F6PQI2 UMPS PTHR19278:SF9 OROTATE PHOSPHORIBOSYLTRANSFERASE URIDINE 5'-MONOPHOSPHATE SYNTHASE glycosyltransferase activity#GO:0016757;lyase activity#GO:0016829;catalytic activity#GO:0003824;transferase activity#GO:0016740;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;pentosyltransferase activity#GO:0016763 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate biosynthetic process#GO:0009124;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;pyrimidine nucleobase metabolic process#GO:0006206;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;transferase#PC00220 De novo pyrimidine ribonucleotides biosythesis#P02740>Orotate phosphoribosyltransferase#P02922 MONDO|Ensembl=ENSMODG00000012331.4|UniProtKB=F7E2P1 F7E2P1 PLCL1 PTHR10336:SF102 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN INACTIVE PHOSPHOLIPASE C-LIKE PROTEIN 1 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;hydrolase activity#GO:0016787;lipase activity#GO:0016298 modulation of chemical synaptic transmission#GO:0050804;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789;cellular process#GO:0009987;cell communication#GO:0007154;regulation of signaling#GO:0023051 hydrolase#PC00121;phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530 MONDO|Ensembl=ENSMODG00000020723.4|UniProtKB=F7ANW2 F7ANW2 ABCG2 PTHR48041:SF92 ABC TRANSPORTER G FAMILY MEMBER 28 BROAD SUBSTRATE SPECIFICITY ATP-BINDING CASSETTE TRANSPORTER ABCG2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;efflux transmembrane transporter activity#GO:0015562;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 xenobiotic transport#GO:0042908;transport#GO:0006810;establishment of localization#GO:0051234;system process#GO:0003008;detoxification of inorganic compound#GO:0061687;cellular process#GO:0009987;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;detoxification#GO:0098754;circulatory system process#GO:0003013;localization#GO:0051179;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;export from cell#GO:0140352 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000007021.4|UniProtKB=A0A5F8G6T1 A0A5F8G6T1 ARRB1 PTHR11792:SF22 ARRESTIN BETA-ARRESTIN-1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664 negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;positive regulation of signal transduction#GO:0009967;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of Notch signaling pathway#GO:0008593;sensory perception#GO:0007600;localization#GO:0051179;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;transport#GO:0006810;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of Notch signaling pathway#GO:0045746;negative regulation of cellular process#GO:0048523;receptor-mediated endocytosis#GO:0006898;system process#GO:0003008;positive regulation of MAPK cascade#GO:0043410;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;endocytosis#GO:0006897;regulation of signaling#GO:0023051;nervous system process#GO:0050877;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;positive regulation of signaling#GO:0023056;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;receptor internalization#GO:0031623;negative regulation of signal transduction#GO:0009968;vesicle-mediated transport#GO:0016192;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of MAPK cascade#GO:0043408;import into cell#GO:0098657 vesicle#GO:0031982;nucleus#GO:0005634;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;cytosol#GO:0005829;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 scaffold/adaptor protein#PC00226 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>beta-arrestin#P00723;Wnt signaling pathway#P00057>beta-arrestin#P01456;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>beta-arrestin#P00880;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>beta-ARR1#P05925 MONDO|Ensembl=ENSMODG00000042431.1|UniProtKB=A0A5F8G7A6 A0A5F8G7A6 PTHR10206:SF2 CATHELICIDIN CATHELICIDIN ANTIMICROBIAL PEPTIDE lipid binding#GO:0008289;lipopolysaccharide binding#GO:0001530;binding#GO:0005488;carbohydrate derivative binding#GO:0097367 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;response to external biotic stimulus#GO:0043207;defense response to Gram-positive bacterium#GO:0050830 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051 MONDO|Ensembl=ENSMODG00000000765.4|UniProtKB=F6SSV5 F6SSV5 PIAS4 PTHR10782:SF9 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS4 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;molecular function inhibitor activity#GO:0140678;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755 cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;metabolic process#GO:0008152;protein sumoylation#GO:0016925;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;post-translational protein modification#GO:0043687;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958;JAK/STAT signaling pathway#P00038>PIAS#P01031 MONDO|Ensembl=ENSMODG00000024652.1|UniProtKB=F6XBA3 F6XBA3 CHRM3 PTHR24247:SF183 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M3 transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;acetylcholine receptor activity#GO:0015464;molecular transducer activity#GO:0060089;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930 signaling#GO:0023052;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of muscle system process#GO:0090257;chemical synaptic transmission#GO:0007268;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;regulation of muscle contraction#GO:0006937;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;regulation of smooth muscle contraction#GO:0006940;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of system process#GO:0044057;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193 synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>mAChR1/3#P01069;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083 MONDO|Ensembl=ENSMODG00000001185.4|UniProtKB=F7GHC9 F7GHC9 RNF11 PTHR46359:SF1 GEO07743P1 RING FINGER PROTEIN 11 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535 MONDO|Ensembl=ENSMODG00000044081.1|UniProtKB=A0A5F8GU59 A0A5F8GU59 PTHR10044:SF79 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 2 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;enzyme regulator activity#GO:0030234;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of protein modification process#GO:0031399;regulation of apoptotic process#GO:0042981;regulation of protein ubiquitination#GO:0031396;negative regulation of cellular process#GO:0048523;regulation of cell cycle#GO:0051726;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of protein modification by small protein conjugation or removal#GO:1903320;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;positive regulation of protein metabolic process#GO:0051247 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 Apoptosis signaling pathway#P00006>c-IAP1,2#P00264;CCKR signaling map#P06959>BIRC2#G07278 MONDO|Ensembl=ENSMODG00000049519.1|UniProtKB=A0A5F8HKZ4 A0A5F8HKZ4 PEBP1 PTHR11362:SF151 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 1 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585 protease inhibitor#PC00191 EGF receptor signaling pathway#P00018>RKIP#P00548;FGF signaling pathway#P00021>RKIP#P00630 MONDO|Ensembl=ENSMODG00000019916.3|UniProtKB=F6VPG8 F6VPG8 PTHR10884:SF17 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000015246.4|UniProtKB=A0A5F8GSQ7 A0A5F8GSQ7 GRM8 PTHR24060:SF26 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066 G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 MONDO|Ensembl=ENSMODG00000003017.3|UniProtKB=F6Q2P1 F6Q2P1 IPO13 PTHR12363:SF33 TRANSPORTIN 3 AND IMPORTIN 13 IMPORTIN-13 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transporter#PC00227 MONDO|Ensembl=ENSMODG00000018416.4|UniProtKB=F6XUY9 F6XUY9 ADIPOR2 PTHR20855:SF33 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to peptide#GO:1901652;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;cytokine-mediated signaling pathway#GO:0019221;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>AdipoR1/R2#P06706 MONDO|Ensembl=ENSMODG00000047249.1|UniProtKB=A0A5F8GKY2 A0A5F8GKY2 monDomV1R1285 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014625.4|UniProtKB=F6YPU1 F6YPU1 PTHR23239:SF96 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 9 structural molecule activity#GO:0005198 epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;morphogenesis of an epithelium#GO:0002009;developmental process#GO:0032502;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000049198.1|UniProtKB=A0A5F8G6L7 A0A5F8G6L7 PTHR11848:SF151 TGF-BETA FAMILY EMBRYONIC GROWTH_DIFFERENTIATION FACTOR 1 molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000005621.4|UniProtKB=F7CZ56 F7CZ56 FZD6 PTHR11309:SF75 FRIZZLED FRIZZLED-6 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;non-canonical Wnt signaling pathway#GO:0035567;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>Frizzled#P00475;Wnt signaling pathway#P00057>Frizzled#P01428;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 MONDO|Ensembl=ENSMODG00000021250.4|UniProtKB=F6TIV1 F6TIV1 PTHR19818:SF167 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000023711.2|UniProtKB=F6VME6 F6VME6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013627.2|UniProtKB=A0A5F8GGT6 A0A5F8GGT6 PTHR10194:SF4 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 4-RELATED GTPase-activating protein#PC00257 FGF signaling pathway#P00021>RasGAP#P00646;PDGF signaling pathway#P00047>RasGAP#P01152;EGF receptor signaling pathway#P00018>GAP#P00546 MONDO|Ensembl=ENSMODG00000000476.5|UniProtKB=F6UAP6 F6UAP6 SLC39A6 PTHR12191:SF22 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP6 solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;bicarbonate transmembrane transporter activity#GO:0015106;zinc ion transmembrane transporter activity#GO:0005385;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;transition metal ion transmembrane transporter activity#GO:0046915;symporter activity#GO:0015293 cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;import across plasma membrane#GO:0098739;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000029705.2|UniProtKB=A0A5F8H814 A0A5F8H814 PTHR24100:SF149 BUTYROPHILIN BG ANTIGEN 1, MHCB REGION-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;immune system process#GO:0002376;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000028752.2|UniProtKB=K7E0W2 K7E0W2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012693.4|UniProtKB=A0A5F8GQ08 A0A5F8GQ08 RPL19 PTHR10722:SF0 60S RIBOSOMAL PROTEIN L19 LARGE RIBOSOMAL SUBUNIT PROTEIN EL19 nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000048539.1|UniProtKB=F7AI44 F7AI44 LOC107649253 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020465.4|UniProtKB=F7FJG7 F7FJG7 E2F7 PTHR12081:SF25 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F7 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000014761.3|UniProtKB=F7GGY7 F7GGY7 WBP4 PTHR13173:SF10 WW DOMAIN BINDING PROTEIN 4 WW DOMAIN-BINDING PROTEIN 4 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011 MONDO|Ensembl=ENSMODG00000017949.3|UniProtKB=F7E3D0 F7E3D0 WBP11 PTHR13361:SF1 WW DOMAIN-BINDING PROTEIN 11 WW DOMAIN-BINDING PROTEIN 11 enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 MONDO|Ensembl=ENSMODG00000051265.1|UniProtKB=K7E325 K7E325 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000044021.1|UniProtKB=A0A5F8G2J2 A0A5F8G2J2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000002285.3|UniProtKB=F7CC22 F7CC22 AHSA2P PTHR13009:SF4 HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1 ACTIVATOR OF 90 KDA HEAT SHOCK PROTEIN ATPASE HOMOLOG 2-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000000774.3|UniProtKB=A0A5F8GYA6 A0A5F8GYA6 KTI12 PTHR12435:SF2 FAMILY NOT NAMED PROTEIN KTI12 HOMOLOG tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774 MONDO|Ensembl=ENSMODG00000000369.4|UniProtKB=H9H9M1 H9H9M1 PTHR11480:SF36 SAPOSIN-RELATED PROSAPOSIN-RELATED lipid metabolic process#GO:0006629;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;metabolic process#GO:0008152;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;regulation of lipid metabolic process#GO:0019216;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000008351.4|UniProtKB=A0A5F8GBT5 A0A5F8GBT5 ASPH PTHR12366:SF33 ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE ASPARTYL_ASPARAGINYL BETA-HYDROXYLASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;regulation of cytosolic calcium ion concentration#GO:0051480 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000010735.4|UniProtKB=F7G7F5 F7G7F5 CRYBB1 PTHR11818:SF12 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN B1 structural molecule activity#GO:0005198 sensory system development#GO:0048880;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;multicellular organism development#GO:0007275;animal organ development#GO:0048513;system process#GO:0003008;sensory perception of light stimulus#GO:0050953;visual perception#GO:0007601;visual system development#GO:0150063;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;sensory perception#GO:0007600;nervous system process#GO:0050877;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000017131.2|UniProtKB=F6U398 F6U398 FLAD1 PTHR23293:SF9 FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE BIFUNCTIONAL FAD DIPHOSPHATASE_FAD SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566 organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate biosynthetic process#GO:1901293;flavin-containing compound metabolic process#GO:0042726;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987 transferase#PC00220;metabolite interconversion enzyme#PC00262 Flavin biosynthesis#P02741>FAD synthetase#P02936 MONDO|Ensembl=ENSMODG00000037862.1|UniProtKB=A0A5F8GMW5 A0A5F8GMW5 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014437.4|UniProtKB=A0A5F8GKV8 A0A5F8GKV8 PPFIBP1 PTHR12587:SF16 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-BETA-1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;neuromuscular junction development#GO:0007528;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;synapse#GO:0045202;presynaptic active zone#GO:0048786;cell junction#GO:0030054;presynapse#GO:0098793 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019644.4|UniProtKB=H9H7D7 H9H7D7 COMT PTHR43836:SF3 CATECHOL O-METHYLTRANSFERASE 1-RELATED CATECHOL O-METHYLTRANSFERASE transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;O-methyltransferase activity#GO:0008171;transferase activity#GO:0016740;catalytic activity#GO:0003824 catecholamine metabolic process#GO:0006584;metabolic process#GO:0008152;amine catabolic process#GO:0009310;catabolic process#GO:0009056;biogenic amine metabolic process#GO:0006576;amine metabolic process#GO:0009308;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958 plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;membrane#GO:0016020;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425 methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>COMT#P00069;Dopamine receptor mediated signaling pathway#P05912>COMT#P05944 MONDO|Ensembl=ENSMODG00000019236.4|UniProtKB=F6QU60 F6QU60 HERC6 PTHR45622:SF11 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC6-RELATED aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000003253.4|UniProtKB=A0A5F8HET5 A0A5F8HET5 SELE PTHR19325:SF493 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING E-SELECTIN carbohydrate binding#GO:0030246;oligosaccharide binding#GO:0070492;carbohydrate derivative binding#GO:0097367;organic acid binding#GO:0043177;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;ion binding#GO:0043167 heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;leukocyte cell-cell adhesion#GO:0007159;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell migration#GO:0016477;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stimulus#GO:0050896;cell adhesion#GO:0007155;immune system process#GO:0002376;leukocyte migration#GO:0050900;response to peptide#GO:1901652 extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 defense/immunity protein#PC00090;complement component#PC00078 MONDO|Ensembl=ENSMODG00000008386.4|UniProtKB=A0A5F8GK40 A0A5F8GK40 ADAM19 PTHR11905:SF19 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 19 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 membrane protein proteolysis#GO:0033619;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;membrane protein ectodomain proteolysis#GO:0006509;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000038325.1|UniProtKB=A0A5F8HG90 A0A5F8HG90 PTHR22748:SF23 AP ENDONUCLEASE EXODEOXYRIBONUCLEASE III 3'-5'-DNA exonuclease activity#GO:0008296;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;catalytic activity, acting on DNA#GO:0140097;DNA exonuclease activity#GO:0004529;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;base-excision repair#GO:0006284;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000018124.4|UniProtKB=F7F1R6 F7F1R6 PTHR28623:SF2 PROTEIN FAM118B PROTEIN FAM118A hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952 MONDO|Ensembl=ENSMODG00000019178.4|UniProtKB=F7AX94 F7AX94 AFM PTHR11385:SF18 SERUM ALBUMIN-RELATED AFAMIN small molecule binding#GO:0036094;binding#GO:0005488;heterocyclic compound binding#GO:1901363 establishment of localization#GO:0051234;vitamin transport#GO:0051180;response to stimulus#GO:0050896;localization#GO:0051179;response to nutrient levels#GO:0031667;transport#GO:0006810 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000000208.5|UniProtKB=F6TF04 F6TF04 DIS3 PTHR23355:SF35 RIBONUCLEASE EXOSOME COMPLEX EXONUCLEASE RRP44 hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;nuclear mRNA surveillance#GO:0071028;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 exoribonuclease#PC00099 MONDO|Ensembl=ENSMODG00000019326.5|UniProtKB=F6XSW0 F6XSW0 PTHR12752:SF12 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000039223.1|UniProtKB=A0A5F8G8T3 A0A5F8G8T3 LOC100619918 PTHR26450:SF43 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000029028.2|UniProtKB=K7E3K6 K7E3K6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000003084.4|UniProtKB=A0A5F8GNR5 A0A5F8GNR5 GTDC1 PTHR13615:SF3 GLYCOSYLTRANSFERASE-LIKE 1 TRNA-QUEUOSINE ALPHA-MANNOSYLTRANSFERASE glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000045995.1|UniProtKB=A0A5F8GWN4 A0A5F8GWN4 DCTPP1 PTHR46523:SF1 DCTP PYROPHOSPHATASE 1 DCTP PYROPHOSPHATASE 1 nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 nucleobase-containing small molecule metabolic process#GO:0055086;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;response to stress#GO:0006950;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;cellular response to stress#GO:0033554;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000009485.4|UniProtKB=F7FN91 F7FN91 RPS14 PTHR11759:SF1 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 SMALL RIBOSOMAL SUBUNIT PROTEIN US11 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;ribosomal small subunit assembly#GO:0000028;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;ribosome biogenesis#GO:0042254;translation#GO:0006412;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000045129.1|UniProtKB=A0A5F8H9W5 A0A5F8H9W5 PTHR19343:SF0 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 23_DELTA VARIABLE 6 peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000015063.3|UniProtKB=F7FHL8 F7FHL8 NELFE PTHR17250:SF0 NEGATIVE ELONGATION FACTOR E NEGATIVE ELONGATION FACTOR E negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000007842.5|UniProtKB=F7ETA6 F7ETA6 LRFN4 PTHR45842:SF3 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 4 cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;regulation of synapse assembly#GO:0051963;regulation of organelle assembly#GO:1902115;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;synaptic membrane adhesion#GO:0099560;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803;cell adhesion#GO:0007155;synapse organization#GO:0050808;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of biological process#GO:0050789;regulation of postsynapse organization#GO:0099175;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043 asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cell surface#GO:0009986;neuron to neuron synapse#GO:0098984;glutamatergic synapse#GO:0098978;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000050851.1|UniProtKB=A0A5F8GYM9 A0A5F8GYM9 PTHR23339:SF55 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE TYPE IVA 1 phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 regulation of cell migration#GO:0030334;positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000038837.1|UniProtKB=A0A5F8GSR0 A0A5F8GSR0 PTHR12817:SF3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 TRAPP complex#GO:0030008;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;Golgi apparatus subcompartment#GO:0098791;vesicle tethering complex#GO:0099023;cis-Golgi network#GO:0005801;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000018959.3|UniProtKB=A0A5F8G2W4 A0A5F8G2W4 GTPBP2 PTHR43721:SF3 ELONGATION FACTOR TU-RELATED GTP-BINDING PROTEIN 2 translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746 translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 translation elongation factor#PC00222 MONDO|Ensembl=ENSMODG00000019282.3|UniProtKB=A0A5F8GN69 A0A5F8GN69 BLTP2 PTHR15678:SF6 ANTIGEN MLAA-22-RELATED BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 2 MONDO|Ensembl=ENSMODG00000047852.1|UniProtKB=A0A5F8GCA8 A0A5F8GCA8 PTHR13401:SF2 RAGULATOR COMPLEX PROTEIN LAMTOR1 RAGULATOR COMPLEX PROTEIN LAMTOR1 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221 intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;lysosomal membrane#GO:0005765;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796 MONDO|Ensembl=ENSMODG00000043673.1|UniProtKB=A0A5F8GZ70 A0A5F8GZ70 LOC100021883 PTHR26450:SF124 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003880.3|UniProtKB=F7DT80 F7DT80 PTHR14239:SF5 DUDULIN-RELATED METALLOREDUCTASE STEAP4 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on metal ions#GO:0016722;catalytic activity#GO:0003824;ferric-chelate reductase activity#GO:0000293 transition metal ion transport#GO:0000041;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 reductase#PC00198 MONDO|Ensembl=ENSMODG00000016027.3|UniProtKB=A0A5F8HGM7 A0A5F8HGM7 INO80D PTHR16198:SF2 INO80 COMPLEX SUBUNIT D INO80 COMPLEX SUBUNIT D membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000013504.4|UniProtKB=A0A5F8HCG0 A0A5F8HCG0 CKB PTHR11547:SF23 ARGININE OR CREATINE KINASE CREATINE KINASE B-TYPE transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793;modified amino acid metabolic process#GO:0006575 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;amino acid kinase#PC00045 MONDO|Ensembl=ENSMODG00000011621.4|UniProtKB=A0A5F8G624 A0A5F8G624 PSMD10 PTHR24126:SF24 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 10 MONDO|Ensembl=ENSMODG00000007959.4|UniProtKB=F7E9V0 F7E9V0 SNX9 PTHR45827:SF2 SORTING NEXIN SORTING NEXIN-9 binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;membrane invagination#GO:0010324;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;cell division#GO:0051301;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;endocytosis#GO:0006897;cytokinetic process#GO:0032506;cytokinesis#GO:0000910;plasma membrane organization#GO:0007009;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;cellular localization#GO:0051641 intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006695.4|UniProtKB=A0A5F8G794 A0A5F8G794 ZC2HC1A PTHR13555:SF25 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1A C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000038663.1|UniProtKB=A0A5F8H332 A0A5F8H332 LOC100010371 PTHR26453:SF156 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019569.4|UniProtKB=F6R8A4 F6R8A4 PDE4D PTHR11347:SF91 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 4D cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794 phosphodiesterase#PC00185;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000000657.4|UniProtKB=F6STN8 F6STN8 LYPD1 PTHR10036:SF7 CD59 GLYCOPROTEIN LY6_PLAUR DOMAIN-CONTAINING PROTEIN 1 signaling receptor inhibitor activity#GO:0030547;molecular function regulator activity#GO:0098772;neurotransmitter receptor regulator activity#GO:0099602;molecular function inhibitor activity#GO:0140678;acetylcholine receptor inhibitor activity#GO:0030550;acetylcholine receptor regulator activity#GO:0030548;signaling receptor regulator activity#GO:0030545 synaptic signaling#GO:0099536;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 MONDO|Ensembl=ENSMODG00000002040.4|UniProtKB=A0A5F8GR29 A0A5F8GR29 C8orf76 PTHR31919:SF1 ZINC FINGERS AND HOMEOBOXES PROTEIN 1, ISOFORM 2 ZINC FINGERS AND HOMEOBOXES PROTEIN 1, ISOFORM 2 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000013528.4|UniProtKB=F7D6P0 F7D6P0 XRCC3 PTHR46487:SF1 DNA REPAIR PROTEIN XRCC3 DNA REPAIR PROTEIN XRCC3 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;four-way junction DNA binding#GO:0000400 metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;double-strand break repair#GO:0006302;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;cellular component assembly#GO:0022607;nucleobase-containing compound metabolic process#GO:0006139;mitotic recombination#GO:0006312;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;telomere organization#GO:0032200;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;replication fork#GO:0005657;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000009482.4|UniProtKB=F7FNI0 F7FNI0 PIWIL2 PTHR22891:SF188 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PIWI-LIKE PROTEIN 2 endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676 gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;male gamete generation#GO:0048232;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulatory ncRNA-mediated gene silencing#GO:0031047;spermatogenesis#GO:0007283;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;nucleic acid metabolic process#GO:0090304;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;multicellular organismal reproductive process#GO:0048609;piRNA processing#GO:0034587;sexual reproduction#GO:0019953 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;intracellular organelle#GO:0043229;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000036978.1|UniProtKB=A0A5F8H1F6 A0A5F8H1F6 NME4 PTHR11349:SF49 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE D, MITOCHONDRIAL phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824 metabolic process#GO:0008152;nucleoside triphosphate biosynthetic process#GO:0009142;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleoside triphosphate metabolic process#GO:0009141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 kinase#PC00137;transferase#PC00220 De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912;De novo purine biosynthesis#P02738>GDP kinase#P02891;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156 MONDO|Ensembl=ENSMODG00000028812.2|UniProtKB=K7E5E8 K7E5E8 LCNL1 PTHR11430:SF77 LIPOCALIN LIPOCALIN-LIKE 1 PROTEIN transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000009949.4|UniProtKB=F6UAU9 F6UAU9 PTHR24064:SF440 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000020872.4|UniProtKB=A0A5F8HDN0 A0A5F8HDN0 PTHR12473:SF8 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED MONDO|Ensembl=ENSMODG00000019790.3|UniProtKB=F7G1H9 F7G1H9 ZBTB43 PTHR46105:SF15 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 43 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000036728.1|UniProtKB=A0A5F8GQH7 A0A5F8GQH7 SLC25A29 PTHR45624:SF61 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179;basic amino acid transmembrane transporter activity#GO:0015174 L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular transport#GO:0046907;amino acid transport#GO:0006865;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;cellular localization#GO:0051641;mitochondrial transmembrane transport#GO:1990542 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000028175.2|UniProtKB=K7E125 K7E125 PTHR10649:SF17 ARYL HYDROCARBON RECEPTOR ARYL HYDROCARBON RECEPTOR 2 sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000017682.3|UniProtKB=F7GFP0 F7GFP0 PTHR12486:SF5 APRATAXIN-RELATED ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000025785.3|UniProtKB=A0A5F8GXI6 A0A5F8GXI6 PTHR37863:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 196-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 196 MONDO|Ensembl=ENSMODG00000025344.1|UniProtKB=F6YM75 F6YM75 PTHR10031:SF59 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT C3, MITOCHONDRIAL primary active transporter#PC00068;transporter#PC00227;ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000028394.2|UniProtKB=K7DZR7 K7DZR7 SNRPE PTHR11193:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN E SMALL NUCLEAR RIBONUCLEOPROTEIN E protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304 spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;U4/U6 x U5 tri-snRNP complex#GO:0046540;cytoplasm#GO:0005737;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000016790.4|UniProtKB=F7G680 F7G680 MRPL24 PTHR12903:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L24 LARGE RIBOSOMAL SUBUNIT PROTEIN UL24M macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000018435.4|UniProtKB=F6S603 F6S603 PHIP PTHR16266:SF4 WD REPEAT DOMAIN 9 PH-INTERACTING PROTEIN regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000018205.4|UniProtKB=F6PGY0 F6PGY0 POPDC2 PTHR12101:SF15 POPEYE DOMAIN CONTAINING PROTEIN POPEYE DOMAIN-CONTAINING PROTEIN 2 small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367 animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;regulation of biological quality#GO:0065008;system development#GO:0048731;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;circulatory system development#GO:0072359;cell differentiation#GO:0030154;developmental process#GO:0032502;regulation of membrane potential#GO:0042391;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;striated muscle cell differentiation#GO:0051146;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;multicellular organismal process#GO:0032501;heart development#GO:0007507;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;tight junction#GO:0070160;sarcolemma#GO:0042383;cell junction#GO:0030054;anchoring junction#GO:0070161;apical junction complex#GO:0043296 MONDO|Ensembl=ENSMODG00000001941.4|UniProtKB=F6VK86 F6VK86 PTHR23359:SF57 NUCLEOTIDE KINASE GENE, 17949-RELATED phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137;nucleotide kinase#PC00172 MONDO|Ensembl=ENSMODG00000020973.5|UniProtKB=A0A5F8HGQ3 A0A5F8HGQ3 BRWD1 PTHR16266:SF26 WD REPEAT DOMAIN 9 BROMODOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000014628.5|UniProtKB=A0A5F8GFE4 A0A5F8GFE4 KRT14 PTHR23239:SF368 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 14 structural molecule activity#GO:0005198 keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;epidermis development#GO:0008544;developmental process#GO:0032502;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009;organelle organization#GO:0006996;cellular process#GO:0009987;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;skin development#GO:0043588 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000001771.4|UniProtKB=F6WJB8 F6WJB8 HEXA PTHR22600:SF39 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE SUBUNIT ALPHA hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;lipid metabolic process#GO:0006629;glycoprotein metabolic process#GO:0009100;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;aminoglycan metabolic process#GO:0006022;ceramide metabolic process#GO:0006672;protein metabolic process#GO:0019538 lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;lysosome#GO:0005764 glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000019321.4|UniProtKB=H9H7B0 H9H7B0 PTHR10159:SF314 DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 regulation of JNK cascade#GO:0046328;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000039572.1|UniProtKB=A0A5F8H7G2 A0A5F8H7G2 NEU3 PTHR10628:SF23 SIALIDASE SIALIDASE-3 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate catabolic process#GO:0016052;ceramide metabolic process#GO:0006672;liposaccharide metabolic process#GO:1903509;oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;glycolipid metabolic process#GO:0006664;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;lysosome#GO:0005764;membrane#GO:0016020;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000049194.1|UniProtKB=A0A5F8HB85 A0A5F8HB85 PTHR21660:SF1 THIOESTERASE SUPERFAMILY MEMBER-RELATED ACYL-COENZYME A THIOESTERASE 13 deacylase activity#GO:0160215;catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617;acyl-CoA hydrolase activity#GO:0016289;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;hydrolase activity#GO:0016787 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 MONDO|Ensembl=ENSMODG00000046477.1|UniProtKB=F6QLH7 F6QLH7 PTHR48001:SF39 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009893.4|UniProtKB=F6Q649 F6Q649 HACD3 PTHR11035:SF20 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 3 hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 dehydratase#PC00091 MONDO|Ensembl=ENSMODG00000014060.4|UniProtKB=A0A5F8GYP2 A0A5F8GYP2 NUP205 PTHR31344:SF0 NUCLEAR PORE COMPLEX PROTEIN NUP205 NUCLEAR PORE COMPLEX PROTEIN NUP205 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nuclear pore organization#GO:0006999 organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000048933.1|UniProtKB=A0A5F8H4M6 A0A5F8H4M6 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000002302.3|UniProtKB=F6YE51 F6YE51 ALG3 PTHR12646:SF0 NOT56 - RELATED DOL-P-MAN:MAN(5)GLCNAC(2)-PP-DOL ALPHA-1,3-MANNOSYLTRANSFERASE mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000010176.4|UniProtKB=A0A5F8GED8 A0A5F8GED8 SLC20A2 PTHR11101:SF83 PHOSPHATE TRANSPORTER SODIUM-DEPENDENT PHOSPHATE TRANSPORTER 2 solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;phosphate transmembrane transporter activity#GO:0005315;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;phosphate ion transport#GO:0006817;inorganic anion transport#GO:0015698;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 MONDO|Ensembl=ENSMODG00000044259.1|UniProtKB=A0A5F8H1G6 A0A5F8H1G6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000015917.3|UniProtKB=F6PJ49 F6PJ49 PGP PTHR19288:SF92 4-NITROPHENYLPHOSPHATASE-RELATED PHOSPHOGLYCOLATE PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000016224.5|UniProtKB=A0A5F8GNM9 A0A5F8GNM9 JPH2 PTHR23085:SF26 GH28348P JUNCTOPHILIN-2 organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;sarcoplasmic reticulum#GO:0016529;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;sarcoplasm#GO:0016528;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000008232.4|UniProtKB=F6ZXW4 F6ZXW4 PTHR46241:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 4 ARMC4 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 2 MONDO|Ensembl=ENSMODG00000042497.1|UniProtKB=A0A5F8G6R6 A0A5F8G6R6 LOC100619630 PTHR26454:SF77 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045117.1|UniProtKB=A0A5F8H0Y4 A0A5F8H0Y4 PTHR24070:SF395 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-1A ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 regulation of transport#GO:0051049;regulation of localization#GO:0032879;response to chemical#GO:0042221;regulation of trans-synaptic signaling#GO:0099177;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;regulation of secretion by cell#GO:1903530;regulation of neurotransmitter transport#GO:0051588;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of neurotransmitter secretion#GO:0046928;signaling#GO:0023052;regulation of synaptic vesicle exocytosis#GO:2000300;negative regulation of biological process#GO:0048519;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;cellular response to nitrogen compound#GO:1901699;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cell communication#GO:0007154;regulation of secretion#GO:0051046;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;regulation of exocytosis#GO:0017157;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 MONDO|Ensembl=ENSMODG00000002239.4|UniProtKB=A0A5F8GP61 A0A5F8GP61 GPBP1L1 PTHR14339:SF10 VASCULIN VASCULIN-LIKE PROTEIN 1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000012397.4|UniProtKB=F6PN14 F6PN14 SERPINA11 PTHR11461:SF154 SERINE PROTEASE INHIBITOR, SERPIN SERPIN A11 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000048148.1|UniProtKB=A0A5F8H5Y6 A0A5F8H5Y6 TXNL4A PTHR12052:SF5 THIOREDOXIN-LIKE PROTEN 4A, 4B THIOREDOXIN-LIKE PROTEIN 4A gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000036419.1|UniProtKB=A0A5F8GXE3 A0A5F8GXE3 PTHR13025:SF5 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN-CONTAINING PROTEIN D1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000043868.1|UniProtKB=A0A5F8HE18 A0A5F8HE18 PTHR24034:SF218 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-LIKE AND EMI DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;transforming growth factor beta binding#GO:0050431;growth factor binding#GO:0019838;protein binding#GO:0005515;cytokine binding#GO:0019955 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000021299.4|UniProtKB=F7G3T7 F7G3T7 USP13 PTHR24006:SF682 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 13 catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000007414.4|UniProtKB=F7EE88 F7EE88 STK33 PTHR44167:SF6 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED SERINE_THREONINE-PROTEIN KINASE 33 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000024965.2|UniProtKB=F6UBY2 F6UBY2 PTHR14572:SF0 PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR MONDO|Ensembl=ENSMODG00000019314.4|UniProtKB=F6YAP6 F6YAP6 LIN54 PTHR12446:SF36 TESMIN/TSO1-RELATED PROTEIN LIN-54 HOMOLOG regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000011564.3|UniProtKB=F6QBM9 F6QBM9 BFSP2 PTHR23239:SF32 INTERMEDIATE FILAMENT PHAKININ intermediate filament cytoskeleton organization#GO:0045104;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000007883.2|UniProtKB=F6ZH28 F6ZH28 PTHR48002:SF67 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019261.4|UniProtKB=A0A5F8GJ21 A0A5F8GJ21 SPAG5 PTHR15347:SF1 SPERM-ASSOCIATED ANTIGEN 5 SPERM-ASSOCIATED ANTIGEN 5 MONDO|Ensembl=ENSMODG00000000867.4|UniProtKB=F7AVP6 F7AVP6 CLRN2 PTHR31548:SF5 CLARIN CLARIN-2 MONDO|Ensembl=ENSMODG00000020467.5|UniProtKB=F7FJ84 F7FJ84 SYT1 PTHR10024:SF239 SYNAPTOTAGMIN SYNAPTOTAGMIN-1 SNARE binding#GO:0000149;phospholipid binding#GO:0005543;binding#GO:0005488;protein binding#GO:0005515;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;synaptic vesicle exocytosis#GO:0016079;synaptic signaling#GO:0099536;positive regulation of vesicle fusion#GO:0031340;exocytosis#GO:0006887;regulation of transport#GO:0051049;regulation of localization#GO:0032879;vesicle-mediated transport in synapse#GO:0099003;regulated exocytosis#GO:0045055;regulation of synaptic vesicle exocytosis#GO:2000300;export from cell#GO:0140352;signaling#GO:0023052;regulation of neurotransmitter secretion#GO:0046928;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;regulation of neurotransmitter transport#GO:0051588;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;positive regulation of cellular process#GO:0048522;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of exocytosis#GO:0017157;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;regulation of secretion#GO:0051046;trans-synaptic signaling#GO:0099537;signal release#GO:0023061 cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;neuron projection#GO:0043005;presynapse#GO:0098793;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;cell projection#GO:0042995;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 MONDO|Ensembl=ENSMODG00000014738.4|UniProtKB=A0A5F8GL12 A0A5F8GL12 ACLY PTHR23118:SF42 ATP-CITRATE SYNTHASE ATP-CITRATE SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 monocarboxylic acid biosynthetic process#GO:0072330;nucleoside phosphate biosynthetic process#GO:1901293;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;nucleobase-containing compound metabolic process#GO:0006139;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;oxoacid metabolic process#GO:0043436;acetyl-CoA metabolic process#GO:0006084;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;carboxylic acid biosynthetic process#GO:0046394 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220 Pyruvate metabolism#P02772>Citrate Lyase#P03137 MONDO|Ensembl=ENSMODG00000038848.1|UniProtKB=F7CT45 F7CT45 PTHR23267:SF313 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 5-2 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000028202.2|UniProtKB=K7E2C8 K7E2C8 PTHR12080:SF56 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE NATURAL KILLER CELL RECEPTOR 2B4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;immune response#GO:0006955;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000024468.2|UniProtKB=F6YIA3 F6YIA3 PTHR13718:SF4 RIBOSOMAL S SUBUNIT SMALL RIBOSOMAL SUBUNIT PROTEIN US5 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000038676.1|UniProtKB=A0A5F8H4W8 A0A5F8H4W8 PTHR10424:SF82 VIRAL ENVELOPE PROTEIN ENVELOPE POLYPROTEIN cell differentiation#GO:0030154;muscle structure development#GO:0061061;myoblast fusion#GO:0007520;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;syncytium formation by cell-cell fusion#GO:0000768;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;striated muscle cell differentiation#GO:0051146;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010048.3|UniProtKB=F6TCY8 F6TCY8 SLC35A2 PTHR10231:SF106 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-GALACTOSE TRANSLOCATOR nucleotide-sugar transmembrane transporter activity#GO:0005338;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;UDP-galactose transmembrane transporter activity#GO:0005459;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nucleotide-sugar transmembrane transport#GO:0015780;nitrogen compound transport#GO:0071705;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 MONDO|Ensembl=ENSMODG00000043749.1|UniProtKB=A0A5F8G600 A0A5F8G600 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001232.4|UniProtKB=F7G7C7 F7G7C7 CSGALNACT2 PTHR12369:SF20 CHONDROITIN SYNTHASE CHONDROITIN SULFATE N-ACETYLGALACTOSAMINYLTRANSFERASE 2 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000016720.3|UniProtKB=A0A5F8G633 A0A5F8G633 ATP5F1C PTHR11693:SF45 ATP SYNTHASE GAMMA CHAIN ATP SYNTHASE F(1) COMPLEX SUBUNIT GAMMA, MITOCHONDRIAL channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;proton channel activity#GO:0015252;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857 nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP biosynthetic process#GO:0006754;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ATP synthase#PC00002 ATP synthesis#P02721>F1 gamma#P02796 MONDO|Ensembl=ENSMODG00000003473.3|UniProtKB=F7DBZ7 F7DBZ7 PTHR23003:SF6 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN M nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;nuclear mRNA surveillance#GO:0071028;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000012263.4|UniProtKB=F6YGH3 F6YGH3 PLK4 PTHR24345:SF89 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK4 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cytoskeleton organization#GO:0007010;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;organelle organization#GO:0006996;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;microtubule cytoskeleton organization#GO:0000226;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;spindle pole#GO:0000922;chromosome#GO:0005694;kinetochore#GO:0000776;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spindle#GO:0005819;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000014399.3|UniProtKB=F6SRF8 F6SRF8 PIGV PTHR12468:SF2 GPI MANNOSYLTRANSFERASE 2 GPI ALPHA-1,6-MANNOSYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030 phospholipid metabolic process#GO:0006644;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;organophosphate metabolic process#GO:0019637;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;mannosyltransferase complex#GO:0031501;membrane#GO:0016020 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000036951.1|UniProtKB=A0A5F8GMR8 A0A5F8GMR8 LENEP PTHR16968:SF2 LENS EPITHELIAL CELL PROTEIN LEP503 LENS EPITHELIAL CELL PROTEIN LEP503 MONDO|Ensembl=ENSMODG00000008538.4|UniProtKB=F7DH17 F7DH17 BCKDHA PTHR43380:SF1 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 transferase complex#GO:1990234;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000018141.5|UniProtKB=F7CXE1 F7CXE1 P3H3 PTHR14049:SF14 LEPRECAN 1 PROLYL 3-HYDROXYLASE 3 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;dioxygenase activity#GO:0051213 metabolic process#GO:0008152;cellular process#GO:0009987 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 extracellular matrix glycoprotein#PC00100 MONDO|Ensembl=ENSMODG00000019904.3|UniProtKB=F6VQA5 F6VQA5 DDB2 PTHR15169:SF0 DAMAGE-SPECIFIC DNA BINDING PROTEIN 2 DNA DAMAGE-BINDING PROTEIN 2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;damaged DNA binding#GO:0003684 cellular response to stress#GO:0033554;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;response to UV#GO:0009411;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;response to radiation#GO:0009314 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 damaged DNA-binding protein#PC00086 p53 pathway#P00059>p48#G04705 MONDO|Ensembl=ENSMODG00000017145.3|UniProtKB=F6TM42 F6TM42 RAI2 PTHR23186:SF3 RETINOIC ACID-INDUCED PROTEIN 2 RETINOIC ACID-INDUCED PROTEIN 2 anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000013752.3|UniProtKB=F6WS45 F6WS45 ARMC12 PTHR47144:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 12 ARMADILLO REPEAT-CONTAINING PROTEIN 12 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000015784.4|UniProtKB=F6Z443 F6Z443 ASZ1 PTHR24157:SF3 ANKYRIN REPEAT, SAM AND BASIC LEUCINE ZIPPER DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT, SAM AND BASIC LEUCINE ZIPPER DOMAIN-CONTAINING PROTEIN 1 negative regulation of biological process#GO:0048519;developmental process involved in reproduction#GO:0003006;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;reproductive process#GO:0022414;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;male gamete generation#GO:0048232;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;spermatogenesis#GO:0007283;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000039869.1|UniProtKB=A0A5F8GEL0 A0A5F8GEL0 LOC100619395 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017676.4|UniProtKB=A0A5F8G3J6 A0A5F8G3J6 ECHDC1 PTHR11941:SF27 ENOYL-COA HYDRATASE-RELATED ETHYLMALONYL-COA DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;hydratase#PC00120;lyase#PC00144 Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163 MONDO|Ensembl=ENSMODG00000013053.3|UniProtKB=F7G0V4 F7G0V4 PTHR20859:SF55 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON LAMBDA RECEPTOR 1 signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004031.4|UniProtKB=F7D6E1 F7D6E1 SPINK4 PTHR21179:SF0 SERINE-TYPE ENDOPEPTIDASE INHIBITOR SERINE PROTEASE INHIBITOR KAZAL-TYPE 4 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000014932.3|UniProtKB=F7FIR7 F7FIR7 RETREG3 PTHR28659:SF1 RETICULON-LIKE PROTEIN RETICULOPHAGY REGULATOR 3 MONDO|Ensembl=ENSMODG00000051189.1|UniProtKB=A0A5F8GN73 A0A5F8GN73 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000041327.1|UniProtKB=A0A5F8GEH7 A0A5F8GEH7 ZNF48 PTHR24376:SF239 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 48 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009615.5|UniProtKB=F6RZZ5 F6RZZ5 ARSI PTHR10342:SF68 ARYLSULFATASE ARYLSULFATASE I hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 MONDO|Ensembl=ENSMODG00000024573.3|UniProtKB=F7BTC0 F7BTC0 ZNF200 PTHR47772:SF1 ZINC FINGER PROTEIN 200 ZINC FINGER PROTEIN 200 MONDO|Ensembl=ENSMODG00000013442.2|UniProtKB=F7G9N0 F7G9N0 ACP7 PTHR45867:SF3 PURPLE ACID PHOSPHATASE ACID PHOSPHATASE TYPE 7 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000010239.4|UniProtKB=F6WLD0 F6WLD0 PLAC8L1 PTHR15907:SF122 DUF614 FAMILY PROTEIN-RELATED PLAC8-LIKE PROTEIN 1 MONDO|Ensembl=ENSMODG00000001731.4|UniProtKB=F6X0A2 F6X0A2 EVC PTHR16795:SF13 LIMBIN/ELLIS-VAN CREVELD PROTEIN EVC COMPLEX MEMBER EVC regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224;cell surface receptor signaling pathway#GO:0007166 cell projection membrane#GO:0031253;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;ciliary membrane#GO:0060170;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000019727.4|UniProtKB=F6X4T1 F6X4T1 DMGDH PTHR13847:SF187 SARCOSINE DEHYDROGENASE-RELATED DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000008307.5|UniProtKB=F7FGY5 F7FGY5 FOXF2 PTHR46262:SF3 FORKHEAD BOX PROTEIN BINIOU FORKHEAD BOX PROTEIN F2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000004113.4|UniProtKB=F6UDP9 F6UDP9 PTHR10574:SF274 NETRIN/LAMININ-RELATED USHERIN tissue development#GO:0009888;anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000003480.4|UniProtKB=A0A5F8GEV1 A0A5F8GEV1 DAPK1 PTHR24342:SF17 SERINE/THREONINE-PROTEIN KINASE 17 DEATH-ASSOCIATED PROTEIN KINASE 1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000005818.4|UniProtKB=F6TV63 F6TV63 PTHR15919:SF13 DAPPER-RELATED DAPPER HOMOLOG 2 negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000003282.4|UniProtKB=A0A5F8H3B3 A0A5F8H3B3 ZC3H14 PTHR14738:SF29 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14 binding#GO:0005488;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of biological quality#GO:0065008;regulation of RNA stability#GO:0043487 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000008153.4|UniProtKB=K7DZI1 K7DZI1 ATP6V0D2 PTHR11028:SF2 VACUOLAR ATP SYNTHASE SUBUNIT AC39 V-TYPE PROTON ATPASE SUBUNIT D 2 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;biological regulation#GO:0065007;intracellular transport#GO:0046907;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;cellular localization#GO:0051641;localization#GO:0051179;regulation of biological quality#GO:0065008 vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;endomembrane system#GO:0012505;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;lytic vacuole#GO:0000323;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;proton-transporting two-sector ATPase complex#GO:0016469;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;early endosome#GO:0005769;ATPase dependent transmembrane transport complex#GO:0098533;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000004846.3|UniProtKB=A0A5F8H4Y5 A0A5F8H4Y5 PTHR10410:SF51 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED BRCA1_BRCA2-CONTAINING COMPLEX SUBUNIT 3 peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;deubiquitinase activity#GO:0101005;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 translation factor#PC00223;translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000002447.4|UniProtKB=F7DZ90 F7DZ90 TMEM182 PTHR32012:SF0 TRANSMEMBRANE PROTEIN 182-RELATED TRANSMEMBRANE PROTEIN 182 MONDO|Ensembl=ENSMODG00000004188.4|UniProtKB=F6Y9Y7 F6Y9Y7 DARS2 PTHR22594:SF56 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARTATE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000021197.2|UniProtKB=F7FCM2 F7FCM2 SCG2 PTHR15119:SF0 SECRETOGRANIN II SECRETOGRANIN-2 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 cell motility#GO:0048870;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure development#GO:0048856;system development#GO:0048731;cell chemotaxis#GO:0060326;chemotaxis#GO:0006935;multicellular organismal process#GO:0032501;cell migration#GO:0016477;tube development#GO:0035295;leukocyte chemotaxis#GO:0030595;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;leukocyte migration#GO:0050900;developmental process#GO:0032502;response to stimulus#GO:0050896;circulatory system development#GO:0072359;granulocyte chemotaxis#GO:0071621;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;granulocyte migration#GO:0097530;response to chemical#GO:0042221;taxis#GO:0042330;cellular process#GO:0009987;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646 vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141 Gonadotropin-releasing hormone receptor pathway#P06664>Scg2#G06880 MONDO|Ensembl=ENSMODG00000014669.4|UniProtKB=F7E808 F7E808 PACS2 PTHR13280:SF15 PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN 2 macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;protein localization to cell periphery#GO:1990778;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;cellular component organization#GO:0016043;catabolic process#GO:0009056;organelle assembly#GO:0070925;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919 MONDO|Ensembl=ENSMODG00000038971.1|UniProtKB=A0A5F8GCI2 A0A5F8GCI2 PTHR11738:SF199 MHC CLASS I NK CELL RECEPTOR IG-LIKE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000018227.3|UniProtKB=A0A5F8H8P0 A0A5F8H8P0 FSTL1 PTHR10913:SF13 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 1 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;developmental process#GO:0032502;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 MONDO|Ensembl=ENSMODG00000004310.4|UniProtKB=A0A5F8GAE4 A0A5F8GAE4 STOX2 PTHR22437:SF2 WINGED HELIX DOMAIN-CONTAINING PROTEIN STORKHEAD-BOX PROTEIN 2 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000023874.1|UniProtKB=F7G9P4 F7G9P4 LOC100027335 PTHR24410:SF8 HL07962P-RELATED PEROXISOMAL BIOSIS FACTOR 11 GAMMA protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000050518.1|UniProtKB=F7GIH9 F7GIH9 LOC100024846 PTHR26452:SF85 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000008196.5|UniProtKB=A0A5F8G7R7 A0A5F8G7R7 IFT88 PTHR44117:SF2 INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 neuron differentiation#GO:0030182;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;neuron projection development#GO:0031175;renal system development#GO:0072001;kidney development#GO:0001822;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular component assembly#GO:0022607;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;microtubule-based transport#GO:0099111;generation of neurons#GO:0048699;cellular localization#GO:0051641;neuron development#GO:0048666;cilium organization#GO:0044782;ear development#GO:0043583;cellular component organization#GO:0016043;cilium assembly#GO:0060271;inner ear receptor cell stereocilium organization#GO:0060122;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;intracellular transport#GO:0046907;sensory organ development#GO:0007423;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;developmental process#GO:0032502;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;neurogenesis#GO:0022008;inner ear development#GO:0048839;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;anatomical structure development#GO:0048856;localization#GO:0051179;non-motile cilium assembly#GO:1905515;system development#GO:0048731;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073 membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630;ciliary base#GO:0097546;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;cilium#GO:0005929;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 MONDO|Ensembl=ENSMODG00000028047.2|UniProtKB=K7E1Y4 K7E1Y4 PTHR22588:SF4 VWFA DOMAIN-CONTAINING PROTEIN COLLAGEN ALPHA-5(VI) CHAIN cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000000268.4|UniProtKB=F6WB93 F6WB93 RAD51 PTHR22942:SF39 RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER DNA REPAIR PROTEIN RAD51 HOMOLOG 1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 homologous recombination#GO:0035825;reproductive process#GO:0022414;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;organelle fission#GO:0048285;sexual reproduction#GO:0019953;mitotic recombination#GO:0006312;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;nucleobase-containing compound metabolic process#GO:0006139;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA repair#GO:0006281;response to stimulus#GO:0050896;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;protein-containing complex assembly#GO:0065003;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;chromosome organization involved in meiotic cell cycle#GO:0070192 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000005083.4|UniProtKB=F6ZED7 F6ZED7 ACIN1 PTHR46589:SF1 APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;exon-exon junction complex#GO:0035145;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000004372.4|UniProtKB=F6W8D5 F6W8D5 PTHR10730:SF28 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN GALACTOSYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000007433.4|UniProtKB=F7DWM5 F7DWM5 TRMU PTHR11933:SF9 TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE MITOCHONDRIAL TRNA-SPECIFIC 2-THIOURIDYLASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;sulfurtransferase activity#GO:0016783;catalytic activity, acting on a tRNA#GO:0140101;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on RNA#GO:0140098 mitochondrial RNA modification#GO:1900864;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;tRNA thio-modification#GO:0034227;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;tRNA wobble position uridine thiolation#GO:0002143;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000042481.1|UniProtKB=A0A5F8HHM0 A0A5F8HHM0 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000154.4|UniProtKB=F6XSY1 F6XSY1 SEL1L3 PTHR44444:SF1 PROTEIN SEL-1 HOMOLOG 3 PROTEIN SEL-1 HOMOLOG 3 MONDO|Ensembl=ENSMODG00000048854.1|UniProtKB=A0A5F8H097 A0A5F8H097 LOC100027637 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005518.4|UniProtKB=F7G5K0 F7G5K0 TOR2A PTHR10760:SF4 TORSIN TORSIN-2A endoplasmic reticulum#GO:0005783;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 Parkinson disease#P00049>Torsin A#P01221 MONDO|Ensembl=ENSMODG00000019571.4|UniProtKB=F6R864 F6R864 RLBP1 PTHR10174:SF200 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED RETINALDEHYDE-BINDING PROTEIN 1 small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000042702.1|UniProtKB=H9H8C9 H9H8C9 LOC100032768 PTHR48001:SF39 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028610.2|UniProtKB=K7E3L2 K7E3L2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000009833.3|UniProtKB=F6WB26 F6WB26 GH1 PTHR11417:SF2 SOMATOTROPIN,PROLACTIN SOMATOTROPIN cytokine receptor binding#GO:0005126;hormone receptor binding#GO:0051427;binding#GO:0005488;signaling receptor binding#GO:0005102;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 response to chemical#GO:0042221;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725;animal organ development#GO:0048513;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of signaling#GO:0023056;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to peptide hormone#GO:0043434;positive regulation of response to stimulus#GO:0048584;cellular response to nitrogen compound#GO:1901699;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of receptor signaling pathway via STAT#GO:1904892;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 MONDO|Ensembl=ENSMODG00000011798.3|UniProtKB=F7CBL9 F7CBL9 PTHR23245:SF25 TRNA METHYLTRANSFERASE TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 2 HOMOLOG methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;tRNA methyltransferase activity#GO:0008175 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000051415.1|UniProtKB=A0A5F8GYN0 A0A5F8GYN0 PTHR24384:SF261 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 719 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000044923.1|UniProtKB=A0A5F8GX71 A0A5F8GX71 PTHR38493:SF1 CHROMOSOME 1 OPEN READING FRAME 167 SFI1 SPINDLE BODY DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000016203.5|UniProtKB=F7FY32 F7FY32 KCNK15 PTHR11003:SF18 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 15 voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000008295.4|UniProtKB=F7FTY5 F7FTY5 EXOC7 PTHR12542:SF41 EXOCYST COMPLEX PROTEIN EXO70 EXOCYST COMPLEX COMPONENT 7 transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;secretion by cell#GO:0032940;exocytosis#GO:0006887;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352 cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;exocyst#GO:0000145;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000020391.4|UniProtKB=F7C055 F7C055 TTC23L PTHR14485:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 23 TETRATRICOPEPTIDE REPEAT PROTEIN 23-LIKE MONDO|Ensembl=ENSMODG00000014647.5|UniProtKB=F7EQA7 F7EQA7 LOC100618392 PTHR23239:SF184 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 42 structural molecule activity#GO:0005198 epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;morphogenesis of an epithelium#GO:0002009;developmental process#GO:0032502;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000005176.4|UniProtKB=F7E7F8 F7E7F8 FAF2 PTHR23322:SF1 FAS-ASSOCIATED PROTEIN FAS-ASSOCIATED FACTOR 2 ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000012030.4|UniProtKB=F7ALT0 F7ALT0 FOXA1 PTHR11829:SF195 FORKHEAD BOX PROTEIN HEPATOCYTE NUCLEAR FACTOR 3-ALPHA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000006210.3|UniProtKB=F6ZSV6 F6ZSV6 PTHR22797:SF37 CARD6/NUCLEOLAR PROTEIN 3 NUCLEOLAR PROTEIN 3 MONDO|Ensembl=ENSMODG00000009062.5|UniProtKB=F7FR20 F7FR20 FAM83H PTHR16181:SF33 PROTEIN FAM83A-RELATED PROTEIN FAM83H kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515 regulation of cell migration#GO:0030334;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;positive regulation of locomotion#GO:0040017;organelle organization#GO:0006996;macromolecule localization#GO:0033036;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of cell migration#GO:0030335;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;intermediate filament-based process#GO:0045103;regulation of cell motility#GO:2000145;localization#GO:0051179;cell communication#GO:0007154;positive regulation of cell motility#GO:2000147;protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;intermediate filament cytoskeleton organization#GO:0045104;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;signaling#GO:0023052 supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000027965.2|UniProtKB=K7E3P7 K7E3P7 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000001159.4|UniProtKB=F7CK98 F7CK98 FAM98B PTHR31353:SF11 FAM98 TRNA-SPLICING LIGASE COMPLEX SUBUNIT FAM98B catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000005463.4|UniProtKB=A0A5F8H1Z1 A0A5F8H1Z1 PTHR10629:SF61 CYTOSINE-SPECIFIC METHYLTRANSFERASE DNA (CYTOSINE-5)-METHYLTRANSFERASE 1 catalytic activity, acting on DNA#GO:0140097;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;DNA binding#GO:0003677;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA methyltransferase#PC00013;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000007976.4|UniProtKB=F6QAK4 F6QAK4 LGALS8 PTHR11346:SF22 GALECTIN GALECTIN-8 carbohydrate binding#GO:0030246;binding#GO:0005488 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000001164.4|UniProtKB=F7CJV5 F7CJV5 SLA PTHR46037:SF5 PROTEIN ENHANCER OF SEVENLESS 2B SRC-LIKE-ADAPTER signaling receptor binding#GO:0005102;binding#GO:0005488;growth factor receptor binding#GO:0070851;protein binding#GO:0005515 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of MAPK cascade#GO:0043408;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;cell communication#GO:0007154 COP9 signalosome#GO:0008180;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000037470.1|UniProtKB=A0A5F8HJ25 A0A5F8HJ25 PTHR23268:SF92 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 3-1 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000032767.2|UniProtKB=A0A5F8GH04 A0A5F8GH04 PTHR35825:SF2 CASEIN KINASE II SUBUNIT ALPHA PRIME-INTERACTING PROTEIN CASEIN KINASE II SUBUNIT ALPHA'-INTERACTING PROTEIN MONDO|Ensembl=ENSMODG00000023129.2|UniProtKB=F7EDJ5 F7EDJ5 PTHR46473:SF5 GH08155P LEUCINE-RICH REPEAT-CONTAINING PROTEIN 55 transmembrane transporter binding#GO:0044325;potassium channel activity#GO:0005267;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;potassium channel regulator activity#GO:0015459;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;binding#GO:0005488;molecular function activator activity#GO:0140677;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;protein binding#GO:0005515;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000005680.3|UniProtKB=F6V3P8 F6V3P8 PTHR19433:SF111 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 4 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to other organism#GO:0051707;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000047607.1|UniProtKB=Q2ABA3 Q2ABA3 T2R3H PTHR11394:SF49 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 3 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038 detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000044960.1|UniProtKB=K7E458 K7E458 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000044848.1|UniProtKB=A0A5F8GBZ0 A0A5F8GBZ0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000006756.4|UniProtKB=F7BUD7 F7BUD7 MOGAT2 PTHR12317:SF74 DIACYLGLYCEROL O-ACYLTRANSFERASE 2-ACYLGLYCEROL O-ACYLTRANSFERASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;neutral lipid metabolic process#GO:0006638 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000050777.1|UniProtKB=A0A5F8HLA2 A0A5F8HLA2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000037251.1|UniProtKB=A0A5F8GHH5 A0A5F8GHH5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000017210.4|UniProtKB=F6TL92 F6TL92 UTRN PTHR12268:SF26 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 UTROPHIN cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;neuromuscular junction development#GO:0007528 neuromuscular junction#GO:0031594;cell junction#GO:0030054;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796;cell projection#GO:0042995;plasma membrane#GO:0005886;synapse#GO:0045202;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000002052.4|UniProtKB=A0A5F8GL41 A0A5F8GL41 TENT4A PTHR23092:SF24 POLY(A) RNA POLYMERASE TERMINAL NUCLEOTIDYLTRANSFERASE 4A transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000003709.3|UniProtKB=F7FA46 F7FA46 LOC100032326 PTHR12718:SF2 CELL CYCLE CONTROL PROTEIN CWF15 SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000001195.4|UniProtKB=F6X9F5 F6X9F5 SPOPL PTHR24413:SF91 SPECKLE-TYPE POZ PROTEIN SPECKLE-TYPE POZ PROTEIN-LIKE ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000007512.4|UniProtKB=F7GJX3 F7GJX3 ZFX PTHR24406:SF6 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED ZINC FINGER X-CHROMOSOMAL PROTEIN C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000011225.4|UniProtKB=F6S7I7 F6S7I7 EEF1D PTHR11595:SF21 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-DELTA nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222 MONDO|Ensembl=ENSMODG00000050435.1|UniProtKB=A0A5F8HEJ1 A0A5F8HEJ1 PTHR35247:SF1 TESTIS-EXPRESSED PROTEIN 43 TESTIS EXPRESSED 43 MONDO|Ensembl=ENSMODG00000007956.3|UniProtKB=F7E9Z3 F7E9Z3 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000037185.1|UniProtKB=F6ZLJ5 F6ZLJ5 VN2R519 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000004114.4|UniProtKB=K7E687 K7E687 FGF3 PTHR11486:SF26 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 3 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;fibroblast growth factor receptor binding#GO:0005104;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515 neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;response to fibroblast growth factor#GO:0071774;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000000715.4|UniProtKB=F6SFT6 F6SFT6 ACMSD PTHR21240:SF27 2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE 2-AMINO-3-CARBOXYMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE lyase activity#GO:0016829;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830 secondary metabolic process#GO:0019748;cellular process#GO:0009987;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 MONDO|Ensembl=ENSMODG00000007524.4|UniProtKB=F7GJR1 F7GJR1 DENND2B PTHR15288:SF5 DENN DOMAIN-CONTAINING PROTEIN 2 DENN DOMAIN-CONTAINING PROTEIN 2B molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;positive regulation of MAPK cascade#GO:0043410;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;recycling endosome#GO:0055037;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000000602.2|UniProtKB=F6TBC9 F6TBC9 PTHR28595:SF1 39S RIBOSOMAL PROTEIN L54, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML54 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000003145.4|UniProtKB=A0A5F8GP37 A0A5F8GP37 ANGEL2 PTHR12121:SF27 CARBON CATABOLITE REPRESSOR PROTEIN 4 RNA 2',3'-CYCLIC PHOSPHATASE ANGEL2 RNA binding#GO:0003723;hydrolase activity#GO:0016787;nucleic acid binding#GO:0003676;RNA nuclease activity#GO:0004540;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;3'-5'-RNA exonuclease activity#GO:0000175;mRNA binding#GO:0003729;exonuclease activity#GO:0004527;binding#GO:0005488;mRNA 3'-UTR binding#GO:0003730;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;phosphoric ester hydrolase activity#GO:0042578 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;mRNA processing#GO:0006397;mitochondrial RNA 3'-end processing#GO:0000965;RNA processing#GO:0006396;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;regulation of mRNA metabolic process#GO:1903311;RNA 3'-end processing#GO:0031123;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of mRNA metabolic process#GO:1903313;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;mitochondrial RNA processing#GO:0000963;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739 mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000014717.3|UniProtKB=F6ZD68 F6ZD68 PTHR24291:SF198 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4F11 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000007622.4|UniProtKB=F7BLA9 F7BLA9 PTHR19229:SF98 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA3 molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 lipid localization#GO:0010876;macromolecule localization#GO:0033036;transport#GO:0006810;localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000019838.4|UniProtKB=F6SAH2 F6SAH2 PTHR35543:SF1 PROTEIN C11ORF74 INTRAFLAGELLAR TRANSPORT-ASSOCIATED PROTEIN binding#GO:0005488;protein-containing complex binding#GO:0044877 reproductive process#GO:0022414;fertilization#GO:0009566;male gamete generation#GO:0048232;gamete generation#GO:0007276;acrosome reaction#GO:0007340;developmental process involved in reproduction#GO:0003006;single fertilization#GO:0007338;multicellular organismal reproductive process#GO:0048609;spermatogenesis#GO:0007283;developmental process#GO:0032502;sexual reproduction#GO:0019953 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;9+0 non-motile cilium#GO:0097731;cytosol#GO:0005829;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000009581.6|UniProtKB=F7AWF2 F7AWF2 KAT5 PTHR10615:SF219 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT5 N-acetyltransferase activity#GO:0008080;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096 response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974 acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 Alzheimer disease-presenilin pathway#P00004>Tip60#P00137;Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093 MONDO|Ensembl=ENSMODG00000015570.5|UniProtKB=A0A5F8GR48 A0A5F8GR48 ATXN2L PTHR12854:SF8 ATAXIN 2-RELATED ATAXIN-2-LIKE PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cytoplasmic stress granule assembly#GO:0034063;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000019438.4|UniProtKB=F6SF46 F6SF46 RASGRF1 PTHR23113:SF193 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR 1 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of synaptic plasticity#GO:0048167;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000024362.1|UniProtKB=F7AHZ5 F7AHZ5 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020085.5|UniProtKB=F7EST8 F7EST8 PTHR22042:SF2 TANKYRASE 1 BINDING PROTEIN 182 KDA TANKYRASE-1-BINDING PROTEIN response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to ionizing radiation#GO:0010212;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to environmental stimulus#GO:0104004;cellular response to radiation#GO:0071478;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;response to radiation#GO:0009314;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;cellular response to abiotic stimulus#GO:0071214;double-strand break repair#GO:0006302 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;CCR4-NOT complex#GO:0030014;chromatin#GO:0000785;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000000203.3|UniProtKB=F6TFD4 F6TFD4 TGM2 PTHR11590:SF6 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 2 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 MONDO|Ensembl=ENSMODG00000043640.1|UniProtKB=A0A5F8HK60 A0A5F8HK60 NKX2-3 PTHR24340:SF32 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000005204.3|UniProtKB=F7A260 F7A260 PRMT5 PTHR10738:SF0 PROTEIN ARGININE N-METHYLTRANSFERASE 5 PROTEIN ARGININE N-METHYLTRANSFERASE 5 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000016205.4|UniProtKB=F7FY31 F7FY31 CCN5 PTHR11348:SF22 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 5 integrin binding#GO:0005178;carbohydrate derivative binding#GO:0097367;cell adhesion molecule binding#GO:0050839;heparin binding#GO:0008201;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102;binding#GO:0005488 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cell adhesion#GO:0007155;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000045834.1|UniProtKB=A0A5F8GV48 A0A5F8GV48 PTHR47300:SF1 PROTEIN KASH5 PROTEIN KASH5 protein-containing complex binding#GO:0044877;binding#GO:0005488 spindle organization#GO:0007051;meiotic nuclear division#GO:0140013;actin filament organization#GO:0007015;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;telomere localization#GO:0034397;cell cycle#GO:0007049;actin cytoskeleton organization#GO:0030036;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;organelle assembly#GO:0070925;organelle localization#GO:0051640;sexual reproduction#GO:0019953;actin filament-based process#GO:0030029;localization#GO:0051179;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;homologous chromosome pairing at meiosis#GO:0007129;chromosome localization#GO:0050000;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;nuclear division#GO:0000280;spindle localization#GO:0051653 organelle envelope#GO:0031967;membrane protein complex#GO:0098796;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;nuclear chromosome#GO:0000228;organelle outer membrane#GO:0031968;endomembrane system#GO:0012505;spindle#GO:0005819;cytoskeleton#GO:0005856;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;spindle pole#GO:0000922;organelle lumen#GO:0043233;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;outer membrane#GO:0019867;intracellular organelle lumen#GO:0070013;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;nuclear envelope#GO:0005635;synaptonemal structure#GO:0099086;chromosome, telomeric region#GO:0000781;protein-containing complex#GO:0032991;condensed chromosome#GO:0000793;nuclear membrane#GO:0031965;bounding membrane of organelle#GO:0098588;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;synaptonemal complex#GO:0000795 MONDO|Ensembl=ENSMODG00000016803.4|UniProtKB=F7FVJ9 F7FVJ9 PTHR13581:SF5 MRG-BINDING PROTEIN MRG_MORF4L-BINDING PROTEIN regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;chromatin#GO:0000785;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000036693.1|UniProtKB=A0A5F8GJS0 A0A5F8GJS0 ISCU PTHR10093:SF15 IRON-SULFUR CLUSTER ASSEMBLY ENZYME NIFU HOMOLOG IRON-SULFUR CLUSTER ASSEMBLY ENZYME ISCU iron ion binding#GO:0005506;ferrous iron binding#GO:0008198;metal ion binding#GO:0046872;iron-sulfur cluster binding#GO:0051536;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000002993.3|UniProtKB=F6Q4B9 F6Q4B9 C1H20orf144 PTHR37335:SF1 RIKEN CDNA 1700003F12 GENE RIKEN CDNA 1700003F12 GENE MONDO|Ensembl=ENSMODG00000011378.5|UniProtKB=F6SP90 F6SP90 ELOVL3 PTHR11157:SF68 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 3 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000014442.4|UniProtKB=F7AUG6 F7AUG6 PTHR18966:SF397 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 3A transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;molecular transducer activity#GO:0060089;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;voltage-gated monoatomic ion channel activity#GO:0005244 regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051 asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>NR3#P01009;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Huntington disease#P00029>NMDA receptor#P00778;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071 MONDO|Ensembl=ENSMODG00000028702.2|UniProtKB=K7E1Z3 K7E1Z3 PTHR11227:SF27 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266 carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;polysaccharide catabolic process#GO:0000272;polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;localization#GO:0051179;vacuole organization#GO:0007033;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091;pexophagy#GO:0000425;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;intracellular protein localization#GO:0008104;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036;macroautophagy#GO:0016236 phagophore assembly site#GO:0000407;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000037413.1|UniProtKB=A0A5F8HH02 A0A5F8HH02 PTHR21731:SF1 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 1-LIKE SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 1-LIKE membraneless organelle#GO:0043228;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;condensed chromosome#GO:0000793;synaptonemal structure#GO:0099086;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000014797.4|UniProtKB=F7DMR8 F7DMR8 AKAP1 PTHR22948:SF75 TUDOR DOMAIN CONTAINING PROTEIN A-KINASE ANCHOR PROTEIN 1, MITOCHONDRIAL binding#GO:0005488;protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 CCKR signaling map#P06959>AKAP#P07184 MONDO|Ensembl=ENSMODG00000011317.4|UniProtKB=F6WJ30 F6WJ30 LIMD1 PTHR24219:SF3 LIM DOMAIN-CONTAINING PROTEIN JUB LIM DOMAIN-CONTAINING PROTEIN 1 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of response to stimulus#GO:0048583;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;negative regulation of protein metabolic process#GO:0051248;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of signal transduction#GO:0009968;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of hippo signaling#GO:0035331;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of translation#GO:0017148;regulation of hippo signaling#GO:0035330;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;miRNA-mediated post-transcriptional gene silencing#GO:0035195 intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;adherens junction#GO:0005912;membraneless organelle#GO:0043228;cell junction#GO:0030054;nucleus#GO:0005634;cell-cell junction#GO:0005911;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000024159.1|UniProtKB=F6WYM7 F6WYM7 GJB2 PTHR11984:SF46 CONNEXIN GAP JUNCTION BETA-2 PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 animal gross anatomical part developmental process#GO:0160108;ear development#GO:0043583;localization#GO:0051179;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;signaling#GO:0023052;cell junction organization#GO:0034330;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;transport#GO:0006810;sensory organ development#GO:0007423;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;establishment of localization#GO:0051234;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;inner ear development#GO:0048839;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular component assembly#GO:0022607 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 gap junction#PC00105;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000014608.4|UniProtKB=F6XGN8 F6XGN8 LOC100013604 PTHR23239:SF121 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 13 structural molecule activity#GO:0005198 cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;developmental process#GO:0032502;morphogenesis of an epithelium#GO:0002009;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;intermediate filament organization#GO:0045109;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000036746.1|UniProtKB=F7D8M0 F7D8M0 LOC100618565 PTHR26453:SF271 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2V1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000049936.1|UniProtKB=A0A5F8G576 A0A5F8G576 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000020753.4|UniProtKB=A0A5F8H4Z5 A0A5F8H4Z5 UGT2A1 PTHR48043:SF140 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2A1 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 MONDO|Ensembl=ENSMODG00000001892.4|UniProtKB=F6WGD5 F6WGD5 GFM2 PTHR43261:SF9 TRANSLATION ELONGATION FACTOR G-RELATED RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;mitochondrial gene expression#GO:0140053;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;translation#GO:0006412 translation factor#PC00223;translational protein#PC00263;translation elongation factor#PC00222 MONDO|Ensembl=ENSMODG00000011236.4|UniProtKB=F6S738 F6S738 SUCLA2 PTHR11815:SF1 SUCCINYL-COA SYNTHETASE BETA CHAIN SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT BETA, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 energy derivation by oxidation of organic compounds#GO:0015980;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ligase#PC00142 MONDO|Ensembl=ENSMODG00000016829.4|UniProtKB=A0A5F8H4G0 A0A5F8H4G0 ZC3H12D PTHR12876:SF11 N4BP1-RELATED RIBONUCLEASE ZC3H12D-RELATED RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000025147.3|UniProtKB=F7F6F9 F7F6F9 LOC100021232 PTHR11407:SF28 LYSOZYME C LYSOZYME C hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;lysozyme activity#GO:0003796;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;defense response to Gram-negative bacterium#GO:0050829;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;defense response#GO:0006952 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000014158.3|UniProtKB=F6UN61 F6UN61 HTR3A PTHR18945:SF52 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3A monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857 transport#GO:0006810;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;synaptic signaling#GO:0099536;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic transmission, cholinergic#GO:0007271;trans-synaptic signaling#GO:0099537;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020 ligand-gated ion channel#PC00141 Gonadotropin-releasing hormone receptor pathway#P06664>5-HT3AR#P06833;5HT3 type receptor mediated signaling pathway#P04375>5HT3 Rec#P04422 MONDO|Ensembl=ENSMODG00000004685.4|UniProtKB=F6TRB2 F6TRB2 CSDE1 PTHR12913:SF1 UNR PROTEIN N-RAS UPSTREAM GENE PROTEIN COLD SHOCK DOMAIN-CONTAINING PROTEIN E1 protein-RNA adaptor activity#GO:0140517;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000015227.4|UniProtKB=A0A5F8GNG2 A0A5F8GNG2 TCAIM PTHR31596:SF1 T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000017320.4|UniProtKB=F6WWW5 F6WWW5 FOXJ3 PTHR46078:SF3 FORKHEAD BOX PROTEIN J2 FAMILY MEMBER FORKHEAD BOX PROTEIN J3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000002707.3|UniProtKB=F7CXV7 F7CXV7 NQO1 PTHR10204:SF1 NAD P H OXIDOREDUCTASE-RELATED NAD(P)H DEHYDROGENASE [QUINONE] 1 oxidoreductase activity#GO:0016491;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000021189.4|UniProtKB=A0A5F8G9F1 A0A5F8G9F1 EPHA4 PTHR46877:SF18 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 4 transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;axon guidance#GO:0007411;axon development#GO:0061564;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045234.1|UniProtKB=A0A5F8GIA4 A0A5F8GIA4 MRPS12 PTHR11652:SF1 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US12M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribosome#GO:0005840 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000023869.3|UniProtKB=F7CW39 F7CW39 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000007981.4|UniProtKB=F7D678 F7D678 ZDHHC14 PTHR22883:SF28 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC14 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein targeting#GO:0006605;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000047578.1|UniProtKB=A0A5F8HAE1 A0A5F8HAE1 PTHR31254:SF1 HYPOTHETICAL PROTEIN LOC690617 TEKTIN BUNDLE-INTERACTING PROTEIN 1 MONDO|Ensembl=ENSMODG00000024423.2|UniProtKB=F7FUX4 F7FUX4 PTHR47033:SF1 CYSTATIN-M CYSTATIN-M endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 tissue development#GO:0009888;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;epidermis development#GO:0008544 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000000095.4|UniProtKB=F6YCC1 F6YCC1 OIT3 PTHR14002:SF18 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ONCOPROTEIN-INDUCED TRANSCRIPT 3 PROTEIN extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009925.4|UniProtKB=A0A5F8GMJ1 A0A5F8GMJ1 TFE3 PTHR45776:SF3 MIP04163P TRANSCRIPTION FACTOR E3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000018732.3|UniProtKB=H9H777 H9H777 MAFF PTHR10129:SF25 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFF sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of epithelial cell differentiation#GO:0030856;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239;regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000051588.1|UniProtKB=K7E3I2 K7E3I2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000040175.1|UniProtKB=A0A5F8GEJ3 A0A5F8GEJ3 THAP5 PTHR46927:SF1 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 5 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000050334.1|UniProtKB=F6RPE9 F6RPE9 PTHR48018:SF121 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5D18 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008754.4|UniProtKB=F6PRR4 F6PRR4 UNC5B PTHR12582:SF6 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5B transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;neuron projection development#GO:0031175;axon guidance#GO:0007411;axon development#GO:0061564;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 MONDO|Ensembl=ENSMODG00000039408.1|UniProtKB=A0A5F8HAF9 A0A5F8HAF9 EBPL PTHR14207:SF1 STEROL ISOMERASE EMOPAMIL-BINDING PROTEIN-LIKE intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824 steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 isomerase#PC00135 MONDO|Ensembl=ENSMODG00000021471.4|UniProtKB=F7GDI3 F7GDI3 NDC80 PTHR10643:SF2 KINETOCHORE PROTEIN NDC80 KINETOCHORE PROTEIN NDC80 HOMOLOG chromosome localization#GO:0050000;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;mitotic cell cycle#GO:0000278;mitotic metaphase chromosome alignment#GO:0007080;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;localization#GO:0051179;organelle fission#GO:0048285;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;nuclear division#GO:0000280;organelle localization#GO:0051640 kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;outer kinetochore#GO:0000940;membraneless organelle#GO:0043228 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000041693.1|UniProtKB=A0A5F8GNT6 A0A5F8GNT6 SIX5 PTHR10390:SF40 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX5 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000047830.1|UniProtKB=F7CAC6 F7CAC6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001982.3|UniProtKB=F6RIE6 F6RIE6 PTHR11134:SF11 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-3 COMPLEX SUBUNIT BETA-2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;Golgi vesicle transport#GO:0048193;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;lysosome organization#GO:0007040;cellular process#GO:0009987;organelle organization#GO:0006996;synaptic vesicle transport#GO:0048489;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;establishment of organelle localization#GO:0051656;cellular component organization#GO:0016043;vesicle cytoskeletal trafficking#GO:0099518;anterograde synaptic vesicle transport#GO:0048490;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;vacuolar transport#GO:0007034;lytic vacuole organization#GO:0080171;transport#GO:0006810;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle localization#GO:0051648;axo-dendritic transport#GO:0008088;vacuole organization#GO:0007033;anterograde axonal transport#GO:0008089;localization#GO:0051179;Golgi to vacuole transport#GO:0006896;axonal transport#GO:0098930;organelle localization#GO:0051640;microtubule-based movement#GO:0007018 coated membrane#GO:0048475;membrane coat#GO:0030117;AP-type membrane coat adaptor complex#GO:0030119;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000049113.1|UniProtKB=A0A5F8G238 A0A5F8G238 PTHR11783:SF212 SULFOTRANSFERASE SULT SULFOTRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000005704.3|UniProtKB=F6UJU0 F6UJU0 ACD PTHR14487:SF3 ADRENOCORTICAL DYSPLASIA PROTEIN ACD ADRENOCORTICAL DYSPLASIA PROTEIN HOMOLOG MONDO|Ensembl=ENSMODG00000002944.5|UniProtKB=A0A5F8GRI1 A0A5F8GRI1 CLSTN1 PTHR14139:SF4 CALSYNTENIN CALSYNTENIN-1 cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515 regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;positive regulation of cellular component organization#GO:0051130;cell adhesion#GO:0007155;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;regulation of biological quality#GO:0065008;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;regulation of cellular component biogenesis#GO:0044087;regulation of developmental process#GO:0050793;positive regulation of developmental process#GO:0051094;positive regulation of synapse assembly#GO:0051965;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cellular component biogenesis#GO:0044089;regulation of synapse assembly#GO:0051963;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007 postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794;cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;cell surface#GO:0009986;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000008626.4|UniProtKB=F6VMM8 F6VMM8 GAD2 PTHR45677:SF11 GLUTAMATE DECARBOXYLASE-RELATED GLUTAMATE DECARBOXYLASE 2 catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 MONDO|Ensembl=ENSMODG00000023977.2|UniProtKB=F7E936 F7E936 LOC100019646 PTHR26450:SF30 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 572 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025107.1|UniProtKB=F6RPK5 F6RPK5 ITPRIPL2 PTHR10656:SF9 CELL FATE DETERMINING PROTEIN MAB21-RELATED INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-INTERACTING PROTEIN-LIKE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 transferase#PC00220;nucleotidyltransferase#PC00174 MONDO|Ensembl=ENSMODG00000051084.1|UniProtKB=A0A5F8GWP3 A0A5F8GWP3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001244.4|UniProtKB=F7FWR3 F7FWR3 HMGXB4 PTHR46584:SF1 HMG DOMAIN-CONTAINING PROTEIN 4 HMG DOMAIN-CONTAINING PROTEIN 4 HMG box transcription factor#PC00024 MONDO|Ensembl=ENSMODG00000014955.4|UniProtKB=F7D0F1 F7D0F1 CBY2 PTHR21533:SF13 LEUCINE-RICH PROTEIN PROTEIN CHIBBY HOMOLOG 2 MONDO|Ensembl=ENSMODG00000006589.4|UniProtKB=A0A5F8GXS2 A0A5F8GXS2 MTNAP1 PTHR13080:SF16 ATP SYNTHASE F CHAIN, MITOCHONDRIAL-RELATED ATP SYNTHASE F(0) COMPLEX SUBUNIT F, MITOCHONDRIAL channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;proton channel activity#GO:0015252;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803 nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135 membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803;proton-transporting ATP synthase complex#GO:0045259;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000041040.1|UniProtKB=A0A5F8G5H6 A0A5F8G5H6 PTHR48092:SF19 KNIRPS-RELATED PROTEIN-RELATED MINERALOCORTICOID RECEPTOR transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;response to steroid hormone#GO:0048545;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cellular response to stimulus#GO:0051716;steroid hormone receptor signaling pathway#GO:0043401;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;intracellular receptor signaling pathway#GO:0030522;cellular response to steroid hormone stimulus#GO:0071383;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000004022.4|UniProtKB=F7D6U6 F7D6U6 PKNOX2 PTHR11850:SF53 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN PKNOX2 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000000170.4|UniProtKB=F7AXC5 F7AXC5 CACNA1S PTHR45628:SF9 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1S voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857 calcium ion transmembrane transport#GO:0070588;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;calcium ion transport#GO:0006816 cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;calcium channel complex#GO:0034704;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096;Gonadotropin-releasing hormone receptor pathway#P06664>L-type Ca2+#P06812 MONDO|Ensembl=ENSMODG00000010275.3|UniProtKB=F6VNU2 F6VNU2 DDX1 PTHR24031:SF307 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX1 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA splicing#GO:0008380;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cytosol#GO:0005829;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000027462.2|UniProtKB=K7DYT3 K7DYT3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000017519.4|UniProtKB=A0A5F8GSL1 A0A5F8GSL1 NLGN4X PTHR43903:SF10 NEUROLIGIN NEUROLIGIN-4, Y-LINKED cell junction#GO:0030054;synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;organelle#GO:0043226;postsynaptic specialization#GO:0099572;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000045366.1|UniProtKB=K7E2K4 K7E2K4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003736.4|UniProtKB=F7EDB8 F7EDB8 NOP14 PTHR23183:SF0 NOP14 NUCLEOLAR PROTEIN 14 rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000001295.3|UniProtKB=F7C004 F7C004 PTHR36294:SF1 TRANSMEMBRANE PROTEIN 139 TRANSMEMBRANE PROTEIN 139 MONDO|Ensembl=ENSMODG00000009804.4|UniProtKB=F6SYB6 F6SYB6 CDYL PTHR43684:SF5 FAMILY NOT NAMED CHROMODOMAIN Y-LIKE PROTEIN isomerase activity#GO:0016853;chromatin-protein adaptor activity#GO:0140463;intramolecular oxidoreductase activity#GO:0016860;histone H3K9me2/3 reader activity#GO:0062072;histone reader activity#GO:0140566;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006 carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;male gamete generation#GO:0048232;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;spermatogenesis#GO:0007283;developmental process#GO:0032502;fatty acid metabolic process#GO:0006631;cellular developmental process#GO:0048869;lipid modification#GO:0030258;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;reproductive process#GO:0022414;catabolic process#GO:0009056;spermatid development#GO:0007286;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;lipid oxidation#GO:0034440;cellular process#GO:0009987;lipid catabolic process#GO:0016042;fatty acid oxidation#GO:0019395;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;small molecule catabolic process#GO:0044282;gamete generation#GO:0007276;small molecule metabolic process#GO:0044281;cell differentiation#GO:0030154;spermatid differentiation#GO:0048515;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062 peroxisome#GO:0005777;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;microbody#GO:0042579;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782 MONDO|Ensembl=ENSMODG00000013395.3|UniProtKB=F7D899 F7D899 SPIN1 PTHR10405:SF15 SPINDLIN SPINDLIN-1 histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;chromatin-protein adaptor activity#GO:0140463 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000021224.5|UniProtKB=A0A5F8GRC2 A0A5F8GRC2 TRIP12 PTHR45670:SF13 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000005019.3|UniProtKB=F7ERI7 F7ERI7 RDH8 PTHR43391:SF8 RETINOL DEHYDROGENASE-RELATED RETINOL DEHYDROGENASE 8 all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824 retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;terpenoid metabolic process#GO:0006721;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000019908.4|UniProtKB=A0A5F8GCM5 A0A5F8GCM5 MYBPC3 PTHR13817:SF20 TITIN MYOSIN-BINDING PROTEIN C, CARDIAC-TYPE structural molecule activity#GO:0005198 striated muscle tissue development#GO:0014706;muscle organ development#GO:0007517;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;heart development#GO:0007507;cellular component assembly#GO:0022607;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell development#GO:0048468;actomyosin structure organization#GO:0031032;circulatory system development#GO:0072359;cell differentiation#GO:0030154;developmental process#GO:0032502;cellular developmental process#GO:0048869;cardiac muscle tissue development#GO:0048738;tissue development#GO:0009888;multicellular organismal process#GO:0032501;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;system development#GO:0048731;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;heart morphogenesis#GO:0003007;muscle cell development#GO:0055001;animal organ morphogenesis#GO:0009887;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036 intracellular organelle#GO:0043229;M band#GO:0031430;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017;contractile muscle fiber#GO:0043292;A band#GO:0031672;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000011216.4|UniProtKB=F7GAT5 F7GAT5 SFXN2 PTHR11153:SF14 SIDEROFLEXIN SIDEROFLEXIN-2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;mitochondrial transmembrane transport#GO:1990542;neutral amino acid transport#GO:0015804;cellular localization#GO:0051641;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;intracellular transport#GO:0046907;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000000557.5|UniProtKB=F6X542 F6X542 POU4F2 PTHR11636:SF41 POU DOMAIN POU DOMAIN, CLASS 4, TRANSCRIPTION FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000004287.4|UniProtKB=A0A5F8GFG0 A0A5F8GFG0 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004088.4|UniProtKB=F6VVR2 F6VVR2 NAT8L PTHR13947:SF11 GNAT FAMILY N-ACETYLTRANSFERASE N-ACETYLASPARTATE SYNTHETASE N-acetyltransferase activity#GO:0008080;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000029771.2|UniProtKB=K7DZM3 K7DZM3 PTHR19433:SF114 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 20-RELATED response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000008099.4|UniProtKB=F7G5W1 F7G5W1 EIF2AK1 PTHR11042:SF160 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000009788.4|UniProtKB=F6SZ89 F6SZ89 TDRD1 PTHR22948:SF4 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 1 anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cell maturation#GO:0048469;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;spermatogenesis#GO:0007283;regulatory ncRNA-mediated gene silencing#GO:0031047;developmental process#GO:0032502;male gamete generation#GO:0048232;multicellular organismal process#GO:0032501;regionalization#GO:0003002;developmental maturation#GO:0021700;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gamete generation#GO:0007276;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;anterior/posterior axis specification#GO:0009948;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;anterior/posterior pattern specification#GO:0009952;metabolic process#GO:0008152;gene expression#GO:0010467;cellular component assembly#GO:0022607;oogenesis#GO:0048477;embryo development#GO:0009790;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;embryonic pattern specification#GO:0009880;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000001073.4|UniProtKB=F7B5H1 F7B5H1 PTHR24242:SF248 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 9A2 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000028918.2|UniProtKB=K7E5U6 K7E5U6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000024702.2|UniProtKB=F7AFF2 F7AFF2 PTHR35451:SF1 NEUROPEPTIDE-LIKE PROTEIN C4ORF48 NELL2-INTERACTING CELL ONTOGENY REGULATOR 1 gamete generation#GO:0007276;male gamete generation#GO:0048232;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;spermatogenesis#GO:0007283;developmental process#GO:0032502;sexual reproduction#GO:0019953 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000018794.3|UniProtKB=A0A5F8HCM6 A0A5F8HCM6 LRRC1 PTHR48051:SF10 FAMILY NOT NAMED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000004493.3|UniProtKB=A0A5F8G1W1 A0A5F8G1W1 PTHR10969:SF100 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3 BETA lipid binding#GO:0008289;protein binding#GO:0005515;enzyme binding#GO:0019899;microtubule binding#GO:0008017;binding#GO:0005488;ubiquitin protein ligase binding#GO:0031625;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;phospholipid binding#GO:0005543;ubiquitin-like protein ligase binding#GO:0044389 response to stimulus#GO:0050896;catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;cellular component disassembly#GO:0022411;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925;cellular response to stress#GO:0033554;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669 vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;vacuolar membrane#GO:0005774;intracellular organelle#GO:0043229;autophagosome#GO:0005776 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000011766.4|UniProtKB=A0A5F8G9Q1 A0A5F8G9Q1 LOC100024047 PTHR46522:SF1 CYTIDINE MONOPHOSPHATE-N-ACETYLNEURAMINIC ACID HYDROXYLASE INACTIVE CYTIDINE MONOPHOSPHATE-N-ACETYLNEURAMINIC ACID HYDROXYLASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-sugar metabolic process#GO:0009225;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176;hydroxylase#PC00122 MONDO|Ensembl=ENSMODG00000019226.4|UniProtKB=F6REA1 F6REA1 FAM13A PTHR15904:SF18 FAM13 PROTEIN FAM13A MONDO|Ensembl=ENSMODG00000049641.1|UniProtKB=A0A5F8HI42 A0A5F8HI42 LURAP1 PTHR33767:SF2 LEUCINE RICH ADAPTOR PROTEIN 1-LIKE LEUCINE RICH ADAPTOR PROTEIN 1 positive regulation of signal transduction#GO:0009967;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of response to stimulus#GO:0048584;regulation of multicellular organismal process#GO:0051239;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628 MONDO|Ensembl=ENSMODG00000004950.3|UniProtKB=A0A5F8GB95 A0A5F8GB95 HSDL1 PTHR44889:SF1 INACTIVE HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 1 INACTIVE HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000011863.3|UniProtKB=F7G340 F7G340 YJU2B PTHR12111:SF2 SPLICING FACTOR YJU2 SPLICING FACTOR YJU2B-RELATED nucleus#GO:0005634;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000002923.4|UniProtKB=A0A5F8GIV4 A0A5F8GIV4 PTHR48614:SF3 AT03386P MAPK-REGULATED COREPRESSOR-INTERACTING PROTEIN 1 MONDO|Ensembl=ENSMODG00000049357.1|UniProtKB=A0A5F8GNH5 A0A5F8GNH5 PTHR43313:SF43 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C ZGC:113142 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000005388.4|UniProtKB=A0A5F8H6Z8 A0A5F8H6Z8 SLC4A10 PTHR11453:SF32 ANION EXCHANGE PROTEIN SODIUM-DRIVEN CHLORIDE BICARBONATE EXCHANGER solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;chloride transmembrane transporter activity#GO:0015108;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509 biological regulation#GO:0065007;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological quality#GO:0065008;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000000527.5|UniProtKB=F6Y513 F6Y513 RNPEP PTHR45726:SF1 LEUKOTRIENE A-4 HYDROLASE AMINOPEPTIDASE B exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000021082.4|UniProtKB=F6UJ27 F6UJ27 LOC100027319 PTHR10224:SF9 ES1 PROTEIN HOMOLOG, MITOCHONDRIAL GLUTAMINE AMIDOTRANSFERASE-LIKE CLASS 1 DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL MONDO|Ensembl=ENSMODG00000009755.3|UniProtKB=F6WT62 F6WT62 PTHR33426:SF54 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000015556.4|UniProtKB=A0A5F8GHT9 A0A5F8GHT9 XRCC5 PTHR12604:SF4 KU AUTOANTIGEN DNA HELICASE DNA REPAIR PROTEIN KU80 telomeric repeat DNA binding#GO:0042162;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;telomere organization#GO:0032200;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DNA helicase#PC00011 MONDO|Ensembl=ENSMODG00000001848.4|UniProtKB=A0A5F8GUR7 A0A5F8GUR7 PTHR15349:SF0 ENDOTHELIAL PROTEIN C RECEPTOR ENDOTHELIAL PROTEIN C RECEPTOR regulation of coagulation#GO:0050818;negative regulation of coagulation#GO:0050819;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein-binding activity modulator#PC00095 Blood coagulation#P00011>EPCR#P00403 MONDO|Ensembl=ENSMODG00000029502.2|UniProtKB=K7E378 K7E378 PTHR23247:SF2 NY-REN-41 ANTIGEN L15 -RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 34 MONDO|Ensembl=ENSMODG00000020301.3|UniProtKB=F7BFG9 F7BFG9 LOC100018462 PTHR10768:SF22 60S RIBOSOMAL PROTEIN L37 LARGE RIBOSOMAL SUBUNIT PROTEIN EL37 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000024419.3|UniProtKB=F7G5Q8 F7G5Q8 LOC103098660 PTHR24271:SF61 KALLIKREIN-RELATED INACTIVE SERINE PROTEASE 37-RELATED serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 regulation of reproductive process#GO:2000241;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;biological regulation#GO:0065007;primary metabolic process#GO:0044238;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 intracellular organelle#GO:0043229;extracellular region#GO:0005576;acrosomal vesicle#GO:0001669;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000012163.3|UniProtKB=A0A5F8H4K6 A0A5F8H4K6 PTHR45777:SF2 METHIONINE AMINOPEPTIDASE 2 METHIONINE AMINOPEPTIDASE 2 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000002946.4|UniProtKB=A0A5F8HHH3 A0A5F8HHH3 RNPC3 PTHR16105:SF0 RNA-BINDING REGION-CONTAINING PROTEIN 3 RNA-BINDING REGION-CONTAINING PROTEIN 3 snRNA binding#GO:0017069;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;pre-mRNA binding#GO:0036002 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681 MONDO|Ensembl=ENSMODG00000017003.4|UniProtKB=F6QF76 F6QF76 RTEL1 PTHR11472:SF34 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER REGULATOR OF TELOMERE ELONGATION HELICASE 1 small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;nucleotide binding#GO:0000166;helicase activity#GO:0004386;enzyme binding#GO:0019899;ATP-dependent activity#GO:0140657;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;nucleic acid conformation isomerase activity#GO:0120545;DNA helicase activity#GO:0003678;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;catalytic activity, acting on DNA#GO:0140097 regulation of double-strand break repair#GO:2000779;telomere organization#GO:0032200;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular component organization#GO:0051129;macromolecule metabolic process#GO:0043170;regulation of telomere maintenance#GO:0032204;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular response to stress#GO:0080135;regulation of DNA recombination#GO:0000018;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA helicase#PC00011;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000020513.4|UniProtKB=F7EP59 F7EP59 TMTC3 PTHR44395:SF1 FAMILY NOT NAMED PROTEIN O-MANNOSYL-TRANSFERASE TMTC3 MONDO|Ensembl=ENSMODG00000010951.4|UniProtKB=A0A5F8GDK5 A0A5F8GDK5 NUP153 PTHR23193:SF23 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE COMPLEX PROTEIN NUP153 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000037408.1|UniProtKB=A0A5F8GCU8 A0A5F8GCU8 PTHR45981:SF1 LD02310P E3 UBIQUITIN-PROTEIN LIGASE MARCHF1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;signaling receptor binding#GO:0005102;binding#GO:0005488;MHC protein binding#GO:0042287;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;response to stimulus#GO:0050896;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;antigen processing and presentation#GO:0019882;protein modification by small protein conjugation or removal#GO:0070647;immune system process#GO:0002376 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;early endosome membrane#GO:0031901;late endosome membrane#GO:0031902;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708 MONDO|Ensembl=ENSMODG00000014687.4|UniProtKB=F7DNL5 F7DNL5 PTHR19944:SF59 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ ALPHA 1 CHAIN protein-containing complex binding#GO:0044877;peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488 regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell adhesion#GO:0045785;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of cellular process#GO:0048522;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of lymphocyte activation#GO:0051249;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;immune system process#GO:0002376;regulation of multicellular organismal process#GO:0051239;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of T cell activation#GO:0050863;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of leukocyte activation#GO:0002696 intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;vesicle#GO:0031982;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 MONDO|Ensembl=ENSMODG00000001748.4|UniProtKB=F6WZM4 F6WZM4 BBX PTHR13059:SF10 HMG-BOX TRANSCRIPTION FACTOR BBX HMG BOX TRANSCRIPTION FACTOR BBX sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 MONDO|Ensembl=ENSMODG00000013454.4|UniProtKB=F7G9A3 F7G9A3 PIM1 PTHR22984:SF29 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE PIM-1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 positive regulation of TORC1 signaling#GO:1904263;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of TOR signaling#GO:0032006;regulation of mitotic cell cycle#GO:0007346;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;positive regulation of intracellular signal transduction#GO:1902533;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;regulation of TORC1 signaling#GO:1903432;regulation of programmed cell death#GO:0043067;positive regulation of signal transduction#GO:0009967;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000016990.4|UniProtKB=F6U5D8 F6U5D8 SEMA3E PTHR11036:SF22 SEMAPHORIN SEMAPHORIN-3E binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;taxis#GO:0042330;response to chemical#GO:0042221;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;system development#GO:0048731;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;chemotaxis#GO:0006935;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of cell migration#GO:0030334;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000008514.4|UniProtKB=A0A5F8GLU1 A0A5F8GLU1 IQSEC1 PTHR10663:SF327 GUANYL-NUCLEOTIDE EXCHANGE FACTOR IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 1 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of endocytosis#GO:0030100 asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000004527.4|UniProtKB=F6UQA5 F6UQA5 CSNK1G2 PTHR11909:SF157 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM GAMMA-2 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 MONDO|Ensembl=ENSMODG00000001963.6|UniProtKB=F6V2G5 F6V2G5 DMBX1 PTHR46639:SF2 DIENCEPHALON/MESENCEPHALON HOMEOBOX PROTEIN 1 DIENCEPHALON_MESENCEPHALON HOMEOBOX PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000016200.4|UniProtKB=A0A5F8GSA5 A0A5F8GSA5 YWHAB PTHR18860:SF28 14-3-3 PROTEIN 14-3-3 PROTEIN BETA_ALPHA scaffold/adaptor protein#PC00226 FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539;Parkinson disease#P00049>14-3-3#P01238;CCKR signaling map#P06959>14-3-3 beta/alpha#P07038 MONDO|Ensembl=ENSMODG00000037651.1|UniProtKB=A0A5F8GQ42 A0A5F8GQ42 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000043460.1|UniProtKB=A0A5F8GPJ1 A0A5F8GPJ1 PTHR24384:SF261 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 719 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000037294.1|UniProtKB=A0A5F8G7Y5 A0A5F8G7Y5 FAM174C PTHR28607:SF2 EXPRESSED PROTEIN PROTEIN FAM174C extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000014827.4|UniProtKB=F7D1N5 F7D1N5 ZNF385D PTHR23067:SF12 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385D membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000019256.4|UniProtKB=F6QSI6 F6QSI6 PIGS PTHR21072:SF13 GPI TRANSAMIDASE COMPONENT PIG-S GPI-ANCHOR TRANSAMIDASE COMPONENT PIGS biosynthetic process#GO:0009058;GPI anchored protein biosynthesis#GO:0180046;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;endoplasmic reticulum membrane#GO:0005789;caspase complex#GO:0008303;cytoplasm#GO:0005737;peptidase complex#GO:1905368;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000018107.1|UniProtKB=F7FFB9 F7FFB9 PIANP PTHR32023:SF2 PILR ALPHA-ASSOCIATED NEURAL PROTEIN PILR ALPHA-ASSOCIATED NEURAL PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000012635.4|UniProtKB=F6WU37 F6WU37 F13B PTHR45785:SF3 COMPLEMENT FACTOR H-RELATED COAGULATION FACTOR XIII B CHAIN response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;hemostasis#GO:0007599;response to wounding#GO:0009611;response to stress#GO:0006950;coagulation#GO:0050817;regulation of biological quality#GO:0065008;wound healing#GO:0042060;blood coagulation#GO:0007596 complement component#PC00078 Blood coagulation#P00011>FXIII#P00453;Vitamin D metabolism and pathway#P04396>RXR#P04602;Blood coagulation#P00011>FXIIIa#P00419 MONDO|Ensembl=ENSMODG00000003359.4|UniProtKB=F6ZPU4 F6ZPU4 REC8 PTHR12585:SF27 SCC1 / RAD21 FAMILY MEMBER MEIOTIC RECOMBINATION PROTEIN REC8 HOMOLOG binding#GO:0005488;chromatin binding#GO:0003682 sister chromatid cohesion#GO:0007062;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cell cycle#GO:0007049;double-strand break repair#GO:0006302;chromosome organization#GO:0051276;meiotic sister chromatid cohesion#GO:0051177;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;replication-born double-strand break repair via sister chromatid exchange#GO:1990414 chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000004264.3|UniProtKB=F6TVH4 F6TVH4 AP4M1 PTHR10529:SF270 AP COMPLEX SUBUNIT MU AP-4 COMPLEX SUBUNIT MU-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 localization#GO:0051179;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;post-Golgi vesicle-mediated transport#GO:0006892;lysosomal transport#GO:0007041;protein targeting#GO:0006605;cytosolic transport#GO:0016482;establishment of localization#GO:0051234;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;AP-type membrane coat adaptor complex#GO:0030119;Golgi apparatus#GO:0005794;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000010087.4|UniProtKB=F6XMA2 F6XMA2 CYB561 PTHR10106:SF14 CYTOCHROME B561-RELATED TRANSMEMBRANE ASCORBATE-DEPENDENT REDUCTASE CYB561 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;carbohydrate homeostasis#GO:0033500;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592 membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000009087.4|UniProtKB=F7FQR8 F7FQR8 LOC100024692 PTHR22950:SF188 AMINO ACID TRANSPORTER PROTON-COUPLED AMINO ACID TRANSPORTER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;neutral L-amino acid transmembrane transporter activity#GO:0015175;amino acid transmembrane transporter activity#GO:0015171;proton transmembrane transporter activity#GO:0015078;glycine transmembrane transporter activity#GO:0015187;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295;monoatomic cation transmembrane transporter activity#GO:0008324 carboxylic acid transmembrane transport#GO:1905039;glycine transport#GO:0015816;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;organic acid transport#GO:0015849;alanine transport#GO:0032328;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600 vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 secondary carrier transporter#PC00258;amino acid transporter#PC00046 MONDO|Ensembl=ENSMODG00000023205.1|UniProtKB=F7CMU3 F7CMU3 PTHR11786:SF8 N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE ARYLAMINE N-ACETYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000002286.4|UniProtKB=F7CC27 F7CC27 PTHR21510:SF16 AKNA DOMAIN-CONTAINING PROTEIN PROTEIN AKNAD1 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000011629.4|UniProtKB=A0A5F8GPT7 A0A5F8GPT7 BNIP2 PTHR12112:SF12 BNIP - RELATED BCL2_ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 2 apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987;programmed cell death#GO:0012501 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000003982.3|UniProtKB=H9H641 H9H641 ADORA2A PTHR24246:SF47 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A2A signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell surface receptor signaling pathway#GO:0007166;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signal transduction#GO:0007165;synaptic transmission, dopaminergic#GO:0001963;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell communication#GO:0007154;G protein-coupled adenosine receptor signaling pathway#GO:0001973;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 MONDO|Ensembl=ENSMODG00000002912.3|UniProtKB=F6PMW7 F6PMW7 CMA1 PTHR24271:SF23 KALLIKREIN-RELATED CHYMASE 2, MAST CELL-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000040895.1|UniProtKB=A0A5F8GKJ4 A0A5F8GKJ4 PTHR24126:SF46 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANKYRIN-3 MONDO|Ensembl=ENSMODG00000014180.4|UniProtKB=F6U6L7 F6U6L7 USP28 PTHR24006:SF678 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 28 catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 cell cycle checkpoint signaling#GO:0000075;DNA damage checkpoint signaling#GO:0000077;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;response to stress#GO:0006950;DNA integrity checkpoint signaling#GO:0031570;cellular process#GO:0009987;regulation of protein stability#GO:0031647;signal transduction#GO:0007165;negative regulation of cell cycle#GO:0045786;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000011033.2|UniProtKB=F7F4B0 F7F4B0 CALHM1 PTHR32261:SF2 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 1 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000015157.4|UniProtKB=F7CF87 F7CF87 NBR1 PTHR20930:SF2 OVARIAN CARCINOMA ANTIGEN CA125-RELATED NEXT TO BRCA1 GENE 1 PROTEIN protein targeting#GO:0006605;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;establishment of protein localization to vacuole#GO:0072666;protein localization to vacuole#GO:0072665;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;intracellular protein transport#GO:0006886;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;metabolic process#GO:0008152;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594 autophagosome#GO:0005776;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000049104.1|UniProtKB=A0A5F8GB28 A0A5F8GB28 PTHR24377:SF641 IP01015P-RELATED ZINC FINGER PROTEIN 354B RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016849.4|UniProtKB=F6VHW5 F6VHW5 IQGAP3 PTHR14149:SF10 RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP3 enzyme activator activity#GO:0008047;calmodulin binding#GO:0005516;cytoskeletal protein binding#GO:0008092;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677 actin filament organization#GO:0007015;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;actomyosin contractile ring assembly#GO:0000915;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin filament-based process#GO:0030029;cytokinetic process#GO:0032506;cortical cytoskeleton organization#GO:0030865;cytokinesis#GO:0000910;supramolecular fiber organization#GO:0097435;mitotic cytokinetic process#GO:1902410;cytoskeleton-dependent cytokinesis#GO:0061640;cortical actin cytoskeleton organization#GO:0030866;cell cycle process#GO:0022402;cell division#GO:0051301;cellular component organization#GO:0016043;cell cycle#GO:0007049;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944 GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000018281.4|UniProtKB=F6Q6F2 F6Q6F2 PM20D2 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000018199.4|UniProtKB=F7B6U0 F7B6U0 CD80 PTHR25466:SF4 T-LYMPHOCYTE ACTIVATION ANTIGEN T-LYMPHOCYTE ACTIVATION ANTIGEN CD80 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>B7#P01337 MONDO|Ensembl=ENSMODG00000012650.3|UniProtKB=F6WDQ6 F6WDQ6 PTHR23267:SF176 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 8-61 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000040081.1|UniProtKB=A0A5F8GN24 A0A5F8GN24 BEND2 PTHR47305:SF1 BEN DOMAIN-CONTAINING PROTEIN 2 BEN DOMAIN CONTAINING 2 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;reproductive process#GO:0022414;cellular response to stress#GO:0033554;sexual reproduction#GO:0019953;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000028847.2|UniProtKB=K7E2N2 K7E2N2 SH3BGRL2 PTHR12232:SF4 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000044653.1|UniProtKB=A0A5F8G963 A0A5F8G963 LOC100617534 PTHR26453:SF0 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13D1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009549.4|UniProtKB=F7BJZ7 F7BJZ7 COPA PTHR19876:SF1 COATOMER COATOMER SUBUNIT ALPHA retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;cytoplasm#GO:0005737;COPI-coated vesicle#GO:0030137;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794 vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000014051.3|UniProtKB=F6U8N8 F6U8N8 KIRREL2 PTHR11640:SF51 NEPHRIN KIN OF IRRE-LIKE PROTEIN 2 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000036711.1|UniProtKB=A0A5F8GTL6 A0A5F8GTL6 PTHR23304:SF189 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000048650.1|UniProtKB=A0A5F8GGB3 A0A5F8GGB3 PTHR23405:SF5 MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED THO COMPLEX SUBUNIT 7 RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleocytoplasmic transport#GO:0006913;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;transcription export complex#GO:0000346;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000012837.4|UniProtKB=F7CTM0 F7CTM0 GPT2 PTHR11751:SF311 ALANINE AMINOTRANSFERASE ALANINE AMINOTRANSFERASE 2 transferase#PC00220;transaminase#PC00216 MONDO|Ensembl=ENSMODG00000023713.3|UniProtKB=F6QQV7 F6QQV7 PTHR33426:SF43 C2H2-TYPE DOMAIN-CONTAINING PROTEIN NADH DEHYDROGENASE SUBUNIT 5 MONDO|Ensembl=ENSMODG00000041739.1|UniProtKB=A0A5F8GR10 A0A5F8GR10 PTHR48002:SF63 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003000.3|UniProtKB=F6Q3U2 F6Q3U2 P4HB PTHR18929:SF101 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;catalytic activity, acting on a protein#GO:0140096;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853 biosynthetic process#GO:0009058;protein folding#GO:0006457;response to stimulus#GO:0050896;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;metabolic process#GO:0008152;response to endoplasmic reticulum stress#GO:0034976 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cell surface#GO:0009986;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;external side of plasma membrane#GO:0009897;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000022503.2|UniProtKB=H9H824 H9H824 PTHR13156:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle membrane#GO:0031090;transporter complex#GO:1990351;respiratory chain complex I#GO:0045271;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000025296.2|UniProtKB=F7A2D9 F7A2D9 LOC100028258 PTHR26452:SF977 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018087.3|UniProtKB=F7FT81 F7FT81 SIM1 PTHR23043:SF22 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA SINGLE-MINDED HOMOLOG 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000000033.3|UniProtKB=F6S1C3 F6S1C3 ARC PTHR15962:SF0 ACTIVITY-REGULATED CYTOSKELETON-ASSOCIATED PROTEIN ACTIVITY-REGULATED CYTOSKELETON-ASSOCIATED PROTEIN regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of synaptic plasticity#GO:0048167;regulation of signaling#GO:0023051;regulation of neuronal synaptic plasticity#GO:0048168;regulation of biological quality#GO:0065008 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;neuron projection cytoplasm#GO:0120111;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000002729.4|UniProtKB=F6Z788 F6Z788 ZCCHC7 PTHR46543:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule catabolic process#GO:0009057;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;nuclear mRNA surveillance#GO:0071028;snRNA metabolic process#GO:0016073;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000048381.1|UniProtKB=A0A5F8GQM8 A0A5F8GQM8 PSTPIP1 PTHR23065:SF51 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROLINE-SERINE-THREONINE PHOSPHATASE-INTERACTING PROTEIN 1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000024025.2|UniProtKB=F7E7R3 F7E7R3 XCR1 PTHR10489:SF730 CELL ADHESION MOLECULE CHEMOKINE XC RECEPTOR 1 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;chemotaxis#GO:0006935;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000009037.4|UniProtKB=F7B263 F7B263 RASEF PTHR47977:SF73 RAS-RELATED PROTEIN RAB RAS AND EF-HAND DOMAIN-CONTAINING PROTEIN ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;GDP binding#GO:0019003;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 transport#GO:0006810;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000049985.1|UniProtKB=A0A5F8GEE4 A0A5F8GEE4 PTHR43272:SF101 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE ACSBG2 ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ligase#PC00142 MONDO|Ensembl=ENSMODG00000012241.3|UniProtKB=F6YH86 F6YH86 PTHR24068:SF581 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 J1 ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096 response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000002589.4|UniProtKB=F7G520 F7G520 CEP131 PTHR31540:SF1 CENTROSOMAL PROTEIN OF 131 KDA CENTROSOMAL PROTEIN OF 131 KDA microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;intraciliary transport#GO:0042073;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;localization#GO:0051179;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;male gamete generation#GO:0048232;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;sperm axoneme assembly#GO:0007288;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;spermatogenesis#GO:0007283;developmental process#GO:0032502;transport#GO:0006810;cell projection organization#GO:0030030;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cilium assembly#GO:0060271;cellular component organization#GO:0016043;sperm motility#GO:0097722;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cellular localization#GO:0051641;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based transport#GO:0099111;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;intraciliary transport involved in cilium assembly#GO:0035735;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;microtubule-based process#GO:0007017 MONDO|Ensembl=ENSMODG00000029329.2|UniProtKB=K7E413 K7E413 PTHR43215:SF18 RADIAL SPOKE HEAD 1 HOMOLOG RADIAL SPOKE HEAD 1 HOMOLOG organelle assembly#GO:0070925;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;reproductive process#GO:0022414;plasma membrane bounded cell projection assembly#GO:0120031;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;cilium#GO:0005929 MONDO|Ensembl=ENSMODG00000008362.4|UniProtKB=F7EJM5 F7EJM5 CNBP PTHR23002:SF117 ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN CCHC-TYPE ZINC FINGER NUCLEIC ACID BINDING PROTEIN mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723 biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;positive regulation of translation#GO:0045727;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of protein metabolic process#GO:0051247 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000004611.2|UniProtKB=F6Y3K4 F6Y3K4 C14orf119 PTHR16260:SF3 SIMILAR TO 1700123O20RIK PROTEIN SIMILAR TO 1700123O20RIK PROTEIN-RELATED MONDO|Ensembl=ENSMODG00000042663.1|UniProtKB=A0A5F8GIK6 A0A5F8GIK6 PTHR11932:SF66 CULLIN CULLIN-4B protein complex scaffold activity#GO:0140378;enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;structural molecule activity#GO:0005198;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;ribosome biogenesis#GO:0042254;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to stimulus#GO:0050896;catabolic process#GO:0009056;ribonucleoprotein complex biogenesis#GO:0022613;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;DNA damage response#GO:0006974;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000018812.3|UniProtKB=F6YZH5 F6YZH5 LOC100017091 PTHR11571:SF101 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE A4 glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466 transferase#PC00220 MONDO|Ensembl=ENSMODG00000043396.1|UniProtKB=F7E7Y8 F7E7Y8 GAMT PTHR32379:SF2 GUANIDINOACETATE N-METHYLTRANSFERASE GUANIDINOACETATE N-METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000040290.1|UniProtKB=F6Z2Y0 F6Z2Y0 PTHR48168:SF1 RNA GUANINE-7 METHYLTRANSFERASE-ACTIVATING SUBUNIT-LIKE (PSEUDOGENE)-RELATED RNA GUANINE-N7 METHYLTRANSFERASE ACTIVATING SUBUNIT-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;enzyme activator activity#GO:0008047 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000015505.4|UniProtKB=F6VZL7 F6VZL7 EHD3 PTHR11216:SF67 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein localization to membrane#GO:0072657;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to plasma membrane#GO:0072659;endocytic recycling#GO:0032456;cell projection organization#GO:0030030;endocytosis#GO:0006897;organelle assembly#GO:0070925;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cell periphery#GO:1990778;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104 perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;recycling endosome#GO:0055037;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000036556.1|UniProtKB=F6SCN4 F6SCN4 LOC100025146 PTHR24256:SF246 TRYPTASE-RELATED SERINE PROTEASE 42-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000014796.5|UniProtKB=F7E6E4 F7E6E4 KCNH4 PTHR10217:SF630 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED DELAYED RECTIFIER POTASSIUM CHANNEL KCNH4 voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000012427.4|UniProtKB=F6PKE9 F6PKE9 LOC100616679 PTHR26453:SF38 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13J1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045151.1|UniProtKB=A0A5F8G2E4 A0A5F8G2E4 OR51C1 PTHR26450:SF195 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011007.3|UniProtKB=F6XIN8 F6XIN8 MLNR PTHR24243:SF3 G-PROTEIN COUPLED RECEPTOR MOTILIN RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000017136.4|UniProtKB=F6TMS9 F6TMS9 PTHR24543:SF295 MULTICOPPER OXIDASE-RELATED RETINOSCHISIN camera-type eye morphogenesis#GO:0048593;sensory system development#GO:0048880;retina development in camera-type eye#GO:0060041;multicellular organismal process#GO:0032501;developmental process#GO:0032502;sensory organ development#GO:0007423;anatomical structure formation involved in morphogenesis#GO:0048646;animal organ development#GO:0048513;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;visual system development#GO:0150063;animal organ morphogenesis#GO:0009887;sensory organ morphogenesis#GO:0090596;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000005755.3|UniProtKB=A0A5F8HE44 A0A5F8HE44 PTHR24058:SF103 DUAL SPECIFICITY PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE PRP4 HOMOLOG phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000044360.1|UniProtKB=A0A5F8GX51 A0A5F8GX51 PTHR12411:SF1058 CYSTEINE PROTEASE FAMILY C1-RELATED DIPEPTIDYL PEPTIDASE 1 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;lysosome#GO:0005764;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000003607.4|UniProtKB=F7C6I7 F7C6I7 CRTC1 PTHR13589:SF14 CREB-REGULATED TRANSCRIPTION COACTIVATOR CREB-REGULATED TRANSCRIPTION COACTIVATOR 1 transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;binding#GO:0005488;transcription coregulator activity#GO:0003712;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;transcription coactivator activity#GO:0003713 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 Gonadotropin-releasing hormone receptor pathway#P06664>TORC1#P06788 MONDO|Ensembl=ENSMODG00000050561.1|UniProtKB=A0A5F8H7J5 A0A5F8H7J5 SNTN PTHR11639:SF134 S100 CALCIUM-BINDING PROTEIN SENTAN calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000003790.4|UniProtKB=A0A5F8G9S0 A0A5F8G9S0 BTNL9 PTHR24100:SF162 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;immune system process#GO:0002376;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000042698.1|UniProtKB=A0A5F8H8W3 A0A5F8H8W3 LOC100016046 PTHR24377:SF1040 IP01015P-RELATED ZINC FINGER PROTEIN 467 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015055.2|UniProtKB=F7FUM2 F7FUM2 COA3 PTHR15642:SF3 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3, MITOCHONDRIAL CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3 HOMOLOG, MITOCHONDRIAL cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000041629.1|UniProtKB=A0A5F8H5Y9 A0A5F8H5Y9 DND1 PTHR21245:SF4 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN DEAD END PROTEIN HOMOLOG 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of gene silencing by regulatory ncRNA#GO:0060966;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;positive regulation of biological process#GO:0048518;positive regulation of biosynthetic process#GO:0009891;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000006989.4|UniProtKB=F6Q9U1 F6Q9U1 KMO PTHR46028:SF2 KYNURENINE 3-MONOOXYGENASE KYNURENINE 3-MONOOXYGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000016002.4|UniProtKB=F7EYX0 F7EYX0 PTHR24346:SF51 MAP/MICROTUBULE AFFINITY-REGULATING KINASE PAS DOMAIN-CONTAINING SERINE_THREONINE-PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;negative regulation of cellular process#GO:0048523;regulation of carbohydrate metabolic process#GO:0006109;regulation of glycogen biosynthetic process#GO:0005979;negative regulation of biosynthetic process#GO:0009890;regulation of polysaccharide metabolic process#GO:0032881;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of macromolecule metabolic process#GO:0010605;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of carbohydrate biosynthetic process#GO:0043255;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000041933.1|UniProtKB=A0A5F8GBA2 A0A5F8GBA2 PTHR24100:SF151 BUTYROPHILIN BUTYROPHILIN-LIKE 12 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000024790.2|UniProtKB=F7G078 F7G078 PCDH7 PTHR24028:SF253 CADHERIN-87A PROTOCADHERIN-7 cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000025672.2|UniProtKB=F6U107 F6U107 PTHR23102:SF19 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-LIKE PROTEIN-RELATED nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000005790.4|UniProtKB=F6XG04 F6XG04 ATG4D PTHR22624:SF36 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4D cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;protein-phosphatidylethanolamide deconjugating activity#GO:0019786;hydrolase activity#GO:0016787 autophagosome organization#GO:1905037;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;autophagy#GO:0006914;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component assembly#GO:0022607;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;macromolecule metabolic process#GO:0043170;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;proteolysis#GO:0006508;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000016465.4|UniProtKB=H9H6V3 H9H6V3 PTHR14456:SF2 INOSITOL POLYPHOSPHATE KINASE 1 INOSITOL-PENTAKISPHOSPHATE 2-KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 kinase#PC00137 MONDO|Ensembl=ENSMODG00000014294.4|UniProtKB=A0A5F8G3U0 A0A5F8G3U0 PTHR11501:SF16 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 4 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;microtubule-based process#GO:0007017;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of microtubule-based movement#GO:0060632;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;generation of neurons#GO:0048699;regulation of microtubule-based process#GO:0032886;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856 axon#GO:0030424;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000000517.3|UniProtKB=F6Y5K4 F6Y5K4 TIMM17A PTHR10485:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM17-A transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transmembrane protein transporter activity#GO:0008320 macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein localization to mitochondrion#GO:0070585;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;protein transport#GO:0015031 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744 transporter#PC00227 MONDO|Ensembl=ENSMODG00000002996.4|UniProtKB=F6Q499 F6Q499 LOC100010216 PTHR10797:SF79 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 7 3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;P-body#GO:0000932;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;CCR4-NOT complex#GO:0030014 RNA metabolism protein#PC00031;mRNA polyadenylation factor#PC00146;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000024209.3|UniProtKB=F6WW54 F6WW54 P2RY11 PTHR24231:SF46 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 11 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000007609.4|UniProtKB=F7C5P3 F7C5P3 MAT2B PTHR10491:SF6 DTDP-4-DEHYDRORHAMNOSE REDUCTASE METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;biosynthetic process#GO:0009058 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 reductase#PC00198 O-antigen biosynthesis#P02757>dTDP-4-dehydrorhamnose reductase#P03050 MONDO|Ensembl=ENSMODG00000013461.4|UniProtKB=F7FYW3 F7FYW3 FGD2 PTHR12673:SF82 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 2 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;filopodium assembly#GO:0046847;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000011532.4|UniProtKB=F6QXD7 F6QXD7 RORA PTHR45805:SF3 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR ROR-ALPHA binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sterol binding#GO:0032934;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;lipid binding#GO:0008289;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;steroid binding#GO:0005496 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;negative regulation of defense response#GO:0031348;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;negative regulation of response to external stimulus#GO:0032102;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000007978.4|UniProtKB=F7D6B0 F7D6B0 C1QTNF2 PTHR15427:SF28 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000040896.1|UniProtKB=A0A5F8G8C4 A0A5F8G8C4 PTHR13229:SF2 PROTEIN KISH-A PROTEIN KISH-A export from cell#GO:0140352;establishment of protein localization#GO:0045184;protein localization to extracellular region#GO:0071692;cellular process#GO:0009987;macromolecule localization#GO:0033036;secretion by cell#GO:0032940;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;protein transport#GO:0015031;localization#GO:0051179;protein secretion#GO:0009306;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000011619.4|UniProtKB=F6UGF2 F6UGF2 TRMT1 PTHR10631:SF14 N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101;tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;tRNA methyltransferase activity#GO:0008175 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000001975.4|UniProtKB=K7E2R3 K7E2R3 GNAI3 PTHR10218:SF230 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-3 molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897 heterotrimeric G-protein#PC00117;G-protein#PC00020 Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Enkephalin release#P05913>G-Protein (i)#P05974;Gonadotropin-releasing hormone receptor pathway#P06664>gnai#P06807;PI3 kinase pathway#P00048>Galpha#P01199;Endogenous cannabinoid signaling#P05730>Galpha#P05751;Opioid proenkephalin pathway#P05915>G-protein#P05994;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;GABA-B receptor II signaling#P05731>Gi/oalpha#P05757;Nicotine pharmacodynamics pathway#P06587>GNAI#P06609;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828 MONDO|Ensembl=ENSMODG00000012269.4|UniProtKB=F6YG91 F6YG91 RSRC2 PTHR22426:SF2 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 MONDO|Ensembl=ENSMODG00000027859.1|UniProtKB=K7E090 K7E090 FOXD1 PTHR11829:SF361 FORKHEAD BOX PROTEIN FORKHEAD BOX D2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000020445.4|UniProtKB=A0A5F8GGH2 A0A5F8GGH2 NARS1 PTHR22594:SF16 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARAGINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000001642.4|UniProtKB=F6T863 F6T863 AVEN PTHR16524:SF2 CELL DEATH REGULATOR AVEN CELL DEATH REGULATOR AVEN negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle#GO:0007346;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789 MONDO|Ensembl=ENSMODG00000028859.2|UniProtKB=K7DZC6 K7DZC6 TP53RK PTHR12209:SF0 NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE EKC_KEOPS COMPLEX SUBUNIT TP53RK catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000006233.4|UniProtKB=F7FS17 F7FS17 PPARG PTHR24082:SF488 NUCLEAR HORMONE RECEPTOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of lipid metabolic process#GO:0019216;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;hormone-mediated signaling pathway#GO:0009755;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 CCKR signaling map#P06959>PPARgamma#P07060;Gonadotropin-releasing hormone receptor pathway#P06664>PPARalpha/gamma#P06744;Gonadotropin-releasing hormone receptor pathway#P06664>PPARgamma#P06721 MONDO|Ensembl=ENSMODG00000016596.3|UniProtKB=F6ZDA6 F6ZDA6 PTHR14958:SF12 POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD5 binding#GO:0005488;protein binding#GO:0005515 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000009226.3|UniProtKB=F7EE50 F7EE50 LOC100009814 PTHR26453:SF150 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000051597.1|UniProtKB=A0A5F8GE95 A0A5F8GE95 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000142.4|UniProtKB=F6XTK4 F6XTK4 NUDT13 PTHR11383:SF3 NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 13 NAD(P)H PYROPHOSPHATASE NUDT13, MITOCHONDRIAL MONDO|Ensembl=ENSMODG00000006170.3|UniProtKB=F7B5J5 F7B5J5 NKX2-4 PTHR24340:SF40 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000041144.1|UniProtKB=A0A5F8HI27 A0A5F8HI27 BRI3 PTHR13551:SF1 BRAIN PROTEIN I3 MEMBRANE PROTEIN BRI3 MONDO|Ensembl=ENSMODG00000010718.2|UniProtKB=F7G7N1 F7G7N1 PPP1R8 PTHR23308:SF74 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE 1 protein serine/threonine phosphatase inhibitor activity#GO:0004865;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of BMP signaling pathway#GO:0030510;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;system development#GO:0048731;anatomical structure development#GO:0048856;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;positive regulation of BMP signaling pathway#GO:0030513;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;axonogenesis#GO:0007409;positive regulation of signaling#GO:0023056;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear speck#GO:0016607;organelle lumen#GO:0043233 RNA splicing factor#PC00148 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Parkinson disease#P00049>Syntaxin#P01215 MONDO|Ensembl=ENSMODG00000013746.5|UniProtKB=F6X7M1 F6X7M1 PTHR23193:SF5 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR ENVELOPE PORE MEMBRANE PROTEIN POM 121C-RELATED structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;nuclear transport#GO:0051169;nuclear export#GO:0051168;protein import into nucleus#GO:0006606;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transporter#PC00227 MONDO|Ensembl=ENSMODG00000007879.4|UniProtKB=F6ZH90 F6ZH90 INTS5 PTHR31697:SF2 INTEGRATOR COMPLEX SUBUNIT 5 INTEGRATOR COMPLEX SUBUNIT 5 snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 integrator complex#GO:0032039;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000007379.4|UniProtKB=A0A5F8GGJ1 A0A5F8GGJ1 PCYT1B PTHR10739:SF20 CYTIDYLYLTRANSFERASE CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE B ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;lipid binding#GO:0008289;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;phospholipid binding#GO:0005543;transferase activity#GO:0016740;phosphatidylcholine binding#GO:0031210 transferase#PC00220 MONDO|Ensembl=ENSMODG00000017664.4|UniProtKB=F6YJC5 F6YJC5 BMP8A PTHR11848:SF119 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 8A-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125 multicellular organism development#GO:0007275;animal organ development#GO:0048513;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000051135.1|UniProtKB=F6XW75 F6XW75 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020311.3|UniProtKB=F7G7N8 F7G7N8 PTHR15683:SF5 SCAFFOLD ATTACHMENT FACTOR B-RELATED SAFB-LIKE TRANSCRIPTION MODULATOR nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000022969.1|UniProtKB=F6UY13 F6UY13 AMIGO3 PTHR24368:SF62 AMPHOTERIN-INDUCED PROTEIN AMPHOTERIN-INDUCED PROTEIN 3 central nervous system development#GO:0007417;brain development#GO:0007420;multicellular organismal process#GO:0032501;head development#GO:0060322;nervous system development#GO:0007399;cell-cell adhesion#GO:0098609;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000042411.1|UniProtKB=F6V0R0 F6V0R0 LOC100026335 PTHR48018:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013402.2|UniProtKB=A0A5F8HEK2 A0A5F8HEK2 CYCS PTHR11961:SF15 CYTOCHROME C CYTOCHROME C, SOMATIC electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060 organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ATP synthesis#P02721>Cyt C#P02798;Apoptosis signaling pathway#P00006>Cytochrome C#P00322 MONDO|Ensembl=ENSMODG00000013487.4|UniProtKB=F6QFG0 F6QFG0 SRFBP1 PTHR23325:SF1 SERUM RESPONSE FACTOR-BINDING SERUM RESPONSE FACTOR-BINDING PROTEIN 1 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904;90S preribosome#GO:0030686;preribosome#GO:0030684 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000023596.3|UniProtKB=F7FQ88 F7FQ88 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000002782.2|UniProtKB=F6YGD8 F6YGD8 NIP7 PTHR23415:SF4 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 HOMOLOG ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000003818.5|UniProtKB=F6YVG1 F6YVG1 MSANTD2 PTHR46933:SF1 MYB/SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 2 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000002951.3|UniProtKB=A0A5F8GK16 A0A5F8GK16 PTHR13563:SF19 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG B tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000000876.4|UniProtKB=F7AV52 F7AV52 ADIPOR1 PTHR20855:SF40 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR PROTEIN 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;cytokine-mediated signaling pathway#GO:0019221;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;response to peptide#GO:1901652;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>AdipoR1/R2#P06706 MONDO|Ensembl=ENSMODG00000009120.2|UniProtKB=F7EYJ1 F7EYJ1 PTHR11947:SF14 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 1, MITOCHONDRIAL protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 regulation of biosynthetic process#GO:0009889;regulation of lipid metabolic process#GO:0019216;regulation of carbohydrate metabolic process#GO:0006109;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000037391.1|UniProtKB=A0A5F8GQJ2 A0A5F8GQJ2 PTHR24399:SF80 ZINC FINGER AND BTB DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of multicellular organismal process#GO:0051239;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000043432.1|UniProtKB=A0A5F8GC22 A0A5F8GC22 PTHR32217:SF2 LYMPHOCYTE ANTIGEN 6H LYMPHOCYTE ANTIGEN 6L MONDO|Ensembl=ENSMODG00000011758.4|UniProtKB=F7CWH2 F7CWH2 XKRX PTHR14297:SF4 MEMBRANE TRANSPORT PROTEIN XK FAMILY MEMBER XK-RELATED PROTEIN 2 MONDO|Ensembl=ENSMODG00000008034.5|UniProtKB=F7CKK1 F7CKK1 EEFSEC PTHR43721:SF11 ELONGATION FACTOR TU-RELATED SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 post-transcriptional regulation of gene expression#GO:0010608;metabolic process#GO:0008152;translational elongation#GO:0006414;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;biosynthetic process#GO:0009058;biological regulation#GO:0065007;gene expression#GO:0010467;translation#GO:0006412;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;protein biosynthetic process#GO:0160307;regulation of macromolecule metabolic process#GO:0060255 translation elongation factor#PC00222 MONDO|Ensembl=ENSMODG00000010437.3|UniProtKB=F6YTI4 F6YTI4 LOC100030458 PTHR26453:SF601 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014530.4|UniProtKB=F7ER39 F7ER39 FDX1 PTHR23426:SF26 FERREDOXIN/ADRENODOXIN ADRENODOXIN, MITOCHONDRIAL metabolic process#GO:0008152;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FDX#P04607 MONDO|Ensembl=ENSMODG00000017505.3|UniProtKB=F7F190 F7F190 PUDP PTHR18901:SF48 2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2 PSEUDOURIDINE-5'-PHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000019729.4|UniProtKB=F6X4Q7 F6X4Q7 RABGAP1 PTHR47219:SF6 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE RAB GTPASE-ACTIVATING PROTEIN 1 binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772 GTPase-activating protein#PC00257;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000044667.1|UniProtKB=F6YSR4 F6YSR4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000004582.4|UniProtKB=A0A5F8H6I4 A0A5F8H6I4 PTHR10269:SF2 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-4 cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 nervous system development#GO:0007399;system development#GO:0048731;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024388.1|UniProtKB=F6Z4Q9 F6Z4Q9 LOC100019687 PTHR48002:SF53 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C15 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027670.2|UniProtKB=A0A5F8H357 A0A5F8H357 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000029241.2|UniProtKB=K7E4F2 K7E4F2 SPEGNB PTHR47633:SF8 IMMUNOGLOBULIN SPEG NEIGHBOR PROTEIN MONDO|Ensembl=ENSMODG00000046365.1|UniProtKB=A0A5F8G8P6 A0A5F8G8P6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009877.4|UniProtKB=F6VTU1 F6VTU1 F13A1 PTHR11590:SF42 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE COAGULATION FACTOR XIII A CHAIN acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 hemostasis#GO:0007599;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;blood coagulation, fibrin clot formation#GO:0072378;protein activation cascade#GO:0072376;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;wound healing#GO:0042060;response to wounding#GO:0009611;response to stress#GO:0006950;coagulation#GO:0050817;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;multicellular organismal process#GO:0032501;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;biological regulation#GO:0065007;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;blood coagulation#GO:0007596 transferase#PC00220 Blood coagulation#P00011>FXIIIa#P00419;Blood coagulation#P00011>FXIII#P00453 MONDO|Ensembl=ENSMODG00000005985.4|UniProtKB=A0A5F8HJQ2 A0A5F8HJQ2 TAS1R1 PTHR24061:SF3 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 1 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007982.3|UniProtKB=F7D5U4 F7D5U4 SEC61A1 PTHR10906:SF19 SECY/SEC61-ALPHA FAMILY MEMBER PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT ALPHA ISOFORM 1 binding#GO:0005488;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transmembrane protein transporter activity#GO:0008320;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 protein transport#GO:0015031;post-translational protein targeting to membrane, translocation#GO:0031204;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;establishment of protein localization to endoplasmic reticulum#GO:0072599;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum membrane#GO:0030867;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;rough endoplasmic reticulum#GO:0005791;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 transporter#PC00227 MONDO|Ensembl=ENSMODG00000011092.5|UniProtKB=F7E5F4 F7E5F4 PHKA1 PTHR10749:SF4 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA, SKELETAL MUSCLE ISOFORM cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 MONDO|Ensembl=ENSMODG00000006091.4|UniProtKB=F7F148 F7F148 PTHR36859:SF1 PROTEIN HIDE1 PROTEIN HIDE1 MONDO|Ensembl=ENSMODG00000002243.4|UniProtKB=A0A5F8GCT9 A0A5F8GCT9 BTBD7 PTHR16064:SF3 BTB POZ DOMAIN CONTAINING 7 BTB_POZ DOMAIN-CONTAINING PROTEIN 7 MONDO|Ensembl=ENSMODG00000045565.1|UniProtKB=A0A5F8H433 A0A5F8H433 PTHR14453:SF107 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN POLY [ADP-RIBOSE] POLYMERASE transcription corepressor activity#GO:0003714;transferase activity#GO:0016740;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;glycosyltransferase activity#GO:0016757;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transcription regulator activity#GO:0140110;pentosyltransferase activity#GO:0016763 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of gene expression#GO:0010629;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biological process#GO:0048519;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000025007.2|UniProtKB=F6TCB8 F6TCB8 RBIS PTHR35544:SF4 RIBOSOMAL BIOGENESIS FACTOR RIBOSOMAL BIOGENESIS FACTOR MONDO|Ensembl=ENSMODG00000007265.4|UniProtKB=F7FQY6 F7FQY6 RIBC2 PTHR14517:SF10 RIB43A-RELATED RIB43A-LIKE WITH COILED-COILS PROTEIN 2 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000024963.2|UniProtKB=F6UBZ6 F6UBZ6 PTHR45635:SF13 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE 3 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000007155.4|UniProtKB=F6RDC8 F6RDC8 DPY19L4 PTHR31488:SF2 DPY-19-LIKE 1, LIKE (H. SAPIENS) C-MANNOSYLTRANSFERASE DPY19L4-RELATED glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000023262.3|UniProtKB=A0A5F8H3G3 A0A5F8H3G3 PTHR10556:SF59 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE VERY-LONG-CHAIN ENOYL-COA REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000013564.3|UniProtKB=F7BIG7 F7BIG7 IL10RA PTHR20859:SF90 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-10 RECEPTOR SUBUNIT ALPHA transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 MONDO|Ensembl=ENSMODG00000037992.1|UniProtKB=A0A5F8GMN8 A0A5F8GMN8 PTHR15427:SF18 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q SUBCOMPONENT SUBUNIT B molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of immune response#GO:0050776;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;positive regulation of immune system process#GO:0002684;complement activation#GO:0006956;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;immune response#GO:0006955;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;biological regulation#GO:0065007;humoral immune response#GO:0006959;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;positive regulation of immune response#GO:0050778 synaptic membrane#GO:0097060;extracellular protein-containing complex#GO:0140392;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;glutamatergic synapse#GO:0098978;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;synapse#GO:0045202 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000028669.2|UniProtKB=F6VGS6 F6VGS6 SELL PTHR19325:SF543 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING L-SELECTIN small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;organic acid binding#GO:0043177;carbohydrate derivative binding#GO:0097367;oligosaccharide binding#GO:0070492;carbohydrate binding#GO:0030246 cell-cell adhesion#GO:0098609;leukocyte cell-cell adhesion#GO:0007159;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stimulus#GO:0050896;cell migration#GO:0016477;cell motility#GO:0048870;immune system process#GO:0002376;leukocyte migration#GO:0050900;cell adhesion#GO:0007155;response to peptide#GO:1901652 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576 defense/immunity protein#PC00090;complement component#PC00078 MONDO|Ensembl=ENSMODG00000048357.1|UniProtKB=A0A5F8GT64 A0A5F8GT64 ANO1 PTHR12308:SF13 ANOCTAMIN ANOCTAMIN-1 gated channel activity#GO:0022836;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;phospholipid scramblase activity#GO:0017128;ligand-gated monoatomic ion channel activity#GO:0015276;lipid carrier activity#GO:0005319;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;intramembrane lipid carrier activity#GO:0140303;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 lipid localization#GO:0010876;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic anion transport#GO:0006820;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;chloride transport#GO:0006821;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;monoatomic anion transmembrane transport#GO:0098656;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000045189.1|UniProtKB=A0A5F8GYM3 A0A5F8GYM3 C1H16orf86 PTHR37867:SF1 CHROMOSOME 16 OPEN READING FRAME 86 CHROMOSOME 18 C16ORF86 HOMOLOG MONDO|Ensembl=ENSMODG00000014216.4|UniProtKB=F6T9T4 F6T9T4 TBX4 PTHR11267:SF29 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;tube development#GO:0035295;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;angiogenesis#GO:0001525;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;cell differentiation#GO:0030154;cell fate specification#GO:0001708;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 MONDO|Ensembl=ENSMODG00000001236.4|UniProtKB=F7FX32 F7FX32 SAFB PTHR15683:SF6 SCAFFOLD ATTACHMENT FACTOR B-RELATED SCAFFOLD ATTACHMENT FACTOR B-RELATED organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000024116.1|UniProtKB=F6V553 F6V553 LOC100021555 PTHR11886:SF91 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN-RELATED binding#GO:0005488;protein binding#GO:0005515 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782 dynein complex#GO:0030286;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000009630.4|UniProtKB=A0A5F8G3Z4 A0A5F8G3Z4 PDS5B PTHR12663:SF1 ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED SISTER CHROMATID COHESION PROTEIN PDS5 HOMOLOG B chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000019526.5|UniProtKB=A0A5F8GUD4 A0A5F8GUD4 TCF15 PTHR23349:SF4 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 15 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000044472.1|UniProtKB=A0A5F8GQJ8 A0A5F8GQJ8 ANKRD63 PTHR24166:SF30 ROLLING PEBBLES, ISOFORM B ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 63 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000023922.3|UniProtKB=A0A5F8H5J6 A0A5F8H5J6 CEP112 PTHR18871:SF2 CENTROSOMAL PROTEIN OF 112 KDA CENTROSOMAL PROTEIN OF 112 KDA MONDO|Ensembl=ENSMODG00000042050.1|UniProtKB=A0A5F8GEG6 A0A5F8GEG6 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000007170.4|UniProtKB=F6RCQ7 F6RCQ7 SLC16A5 PTHR11360:SF21 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 6 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178 transporter#PC00227 MONDO|Ensembl=ENSMODG00000007908.4|UniProtKB=F6YSD0 F6YSD0 GALT PTHR11943:SF1 GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;phosphorus metabolic process#GO:0006793;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 nucleotidyltransferase#PC00174 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992;Fructose galactose metabolism#P02744>Hexose 1-P uridyltransferase#P02964 MONDO|Ensembl=ENSMODG00000039007.1|UniProtKB=A0A5F8HH50 A0A5F8HH50 LOC100617546 PTHR48018:SF5 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8A1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040102.1|UniProtKB=A0A5F8HB84 A0A5F8HB84 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000023089.2|UniProtKB=F7B148 F7B148 TEDDM1 PTHR46441:SF3 TRANSMEMBRANE EPIDIDYMAL FAMILY MEMBER 3 TRANSMEMBRANE EPIDIDYMAL FAMILY MEMBER 3 MONDO|Ensembl=ENSMODG00000028065.2|UniProtKB=K7E169 K7E169 PTHR12133:SF1 TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE, MITOCHONDRIAL tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a tRNA#GO:0140101;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;methylation#GO:0032259;macromolecule modification#GO:0043412;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000011015.3|UniProtKB=H9H6H0 H9H6H0 RASSF7 PTHR15286:SF11 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 7 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014421.4|UniProtKB=F7BH48 F7BH48 KLHL42 PTHR45972:SF2 BTB_2 DOMAIN-CONTAINING PROTEIN KELCH-LIKE PROTEIN 42 catabolic process#GO:0009056;regulation of cellular process#GO:0050794;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;regulation of microtubule-based process#GO:0032886;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 MONDO|Ensembl=ENSMODG00000017426.4|UniProtKB=A0A5F8HJY1 A0A5F8HJY1 PTHR20859:SF51 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-22 RECEPTOR SUBUNIT ALPHA-2 transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020118.3|UniProtKB=F7DRH8 F7DRH8 PTHR48018:SF110 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004768.2|UniProtKB=F6X0E3 F6X0E3 KCNJ1 PTHR11767:SF6 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 1 voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261 transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000017590.4|UniProtKB=F7B4N3 F7B4N3 HECTD1 PTHR45670:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 E3 UBIQUITIN-PROTEIN LIGASE HECTD1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000010847.3|UniProtKB=F7ARL4 F7ARL4 PTHR23140:SF0 RNA PROCESSING PROTEIN LD23810P U2 SNRNP-ASSOCIATED SURP MOTIF-CONTAINING PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000017817.4|UniProtKB=F6ZXP6 F6ZXP6 OSCP1 PTHR21439:SF0 OXIDORED-NITRO DOMAIN-CONTAINING PROTEIN PROTEIN OSCP1 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000019190.4|UniProtKB=F7A9J3 F7A9J3 MTHFD2L PTHR48099:SF7 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED BIFUNCTIONAL METHYLENETETRAHYDROFOLATE DEHYDROGENASE_CYCLOHYDROLASE 2, MITOCHONDRIAL hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;oxidoreductase activity#GO:0016491;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;tetrahydrofolate metabolic process#GO:0046653;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 MONDO|Ensembl=ENSMODG00000029420.2|UniProtKB=F6W793 F6W793 ST6GALNAC5 PTHR45906:SF5 ALPHA-N-ACETYL-NEURAMINYL-2,3-BETA-GALACTOSYL-1, 3-N-ACETYL-GALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE-LIKE ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 5 sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycosphingolipid biosynthetic process#GO:0006688;glycolipid biosynthetic process#GO:0009247;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;carbohydrate metabolic process#GO:0005975;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;carbohydrate derivative biosynthetic process#GO:1901137;oligosaccharide metabolic process#GO:0009311;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 MONDO|Ensembl=ENSMODG00000007698.4|UniProtKB=F7F9J1 F7F9J1 ALOXE3 PTHR11771:SF184 LIPOXYGENASE HYDROPEROXIDE ISOMERASE ALOXE3 catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;icosanoid metabolic process#GO:0006690;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;lipid modification#GO:0030258;arachidonate metabolic process#GO:0019369;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000000447.4|UniProtKB=F6USZ9 F6USZ9 EVX1 PTHR46294:SF2 SEGMENTATION PROTEIN EVEN-SKIPPED HOMEOBOX EVEN-SKIPPED HOMOLOG PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000001996.5|UniProtKB=F6RHT5 F6RHT5 NSUN4 PTHR22808:SF32 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 5-CYTOSINE RRNA METHYLTRANSFERASE NSUN4 RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 protein-RNA complex assembly#GO:0022618;macromolecule modification#GO:0043412;mitochondrial RNA metabolic process#GO:0000959;rRNA processing#GO:0006364;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;mitochondrial large ribosomal subunit assembly#GO:1902775;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;mitochondrial ribosome assembly#GO:0061668;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribosomal large subunit assembly#GO:0000027;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;mitochondrial RNA modification#GO:1900864;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000015213.4|UniProtKB=F6V4I6 F6V4I6 KDM4C PTHR10694:SF104 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4C catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;protein demethylase activity#GO:0140457;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000002058.5|UniProtKB=A0A5F8HAN8 A0A5F8HAN8 DMXL2 PTHR13950:SF13 RABCONNECTIN-RELATED DMX-LIKE PROTEIN 2 localization#GO:0051179;cellular localization#GO:0051641;regulation of cellular process#GO:0050794;cellular component organization#GO:0016043;regulation of transmembrane transport#GO:0034762;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of transport#GO:0051049;regulation of localization#GO:0032879;endosomal transport#GO:0016197;protein-containing complex organization#GO:0043933;regulation of monoatomic cation transmembrane transport#GO:1904062;intracellular transport#GO:0046907;transport#GO:0006810;regulation of monoatomic ion transport#GO:0043269;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;regulation of monoatomic ion transmembrane transport#GO:0034765;early endosome to late endosome transport#GO:0045022;cellular process#GO:0009987 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transport vesicle#GO:0030133;presynapse#GO:0098793;secretory vesicle#GO:0099503;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000022540.2|UniProtKB=F7B9C2 F7B9C2 LOC100027547 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027806.2|UniProtKB=K7E414 K7E414 PTHR46858:SF13 OS05G0521000 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE MDM2 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of cell cycle#GO:0045787;negative regulation of signal transduction#GO:0009968;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of apoptotic process#GO:0042981;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of intrinsic apoptotic signaling pathway#GO:2001242;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;protein metabolic process#GO:0019538;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;positive regulation of mitotic cell cycle#GO:0045931;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 p53 pathway feedback loops 2#P04398>MDM-2#G04709;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#G04674;P53 pathway feedback loops 1#P04392>Mdm2#P04536;P53 pathway feedback loops 1#P04392>MDM-2#G04682;p53 pathway#P00059>Mdm2#P01483;Ubiquitin proteasome pathway#P00060>E3#P01490;p53 pathway#P00059>MDM-2#G01563;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#P04496;p53 pathway feedback loops 2#P04398>Mdm2#P04663 MONDO|Ensembl=ENSMODG00000009543.4|UniProtKB=F7C412 F7C412 PNLIPRP1 PTHR11610:SF108 LIPASE INACTIVE PANCREATIC LIPASE-RELATED PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298 lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000040759.1|UniProtKB=A0A5F8GP04 A0A5F8GP04 LOC100617124 PTHR24381:SF478 ZINC FINGER PROTEIN ZFP14 ZINC FINGER PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016059.4|UniProtKB=F7GIW9 F7GIW9 SLC7A14 PTHR43243:SF17 INNER MEMBRANE TRANSPORTER YGJI-RELATED SOLUTE CARRIER FAMILY 7 MEMBER 14 amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;amino acid transport#GO:0006865;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;amino acid transporter#PC00046 MONDO|Ensembl=ENSMODG00000047251.1|UniProtKB=F7E8J6 F7E8J6 PTHR26450:SF46 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51F1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015746.3|UniProtKB=F7AHQ7 F7AHQ7 CERK PTHR12358:SF25 SPHINGOSINE KINASE CERAMIDE KINASE lipid kinase activity#GO:0001727;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 lipid metabolic process#GO:0006629;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metabolite interconversion enzyme#PC00262;kinase#PC00137;transferase#PC00220 MONDO|Ensembl=ENSMODG00000024998.3|UniProtKB=F7AG35 F7AG35 PPP2R3A PTHR14095:SF3 PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT ALPHA molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;developmental process#GO:0032502;anterior/posterior pattern specification#GO:0009952;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;regulation of canonical Wnt signaling pathway#GO:0060828;embryo development#GO:0009790;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regionalization#GO:0003002;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelium development#GO:0060429;embryo development ending in birth or egg hatching#GO:0009792;regulation of signaling#GO:0023051;pattern specification process#GO:0007389;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;protein-containing complex#GO:0032991 protein phosphatase#PC00195;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000020140.3|UniProtKB=F7D5M9 F7D5M9 PTHR26452:SF253 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10Q1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000019646.4|UniProtKB=H9H7D8 H9H7D8 PTHR11005:SF26 LYSOSOMAL ACID LIPASE-RELATED LYSOSOMAL ACID LIPASE_CHOLESTERYL ESTER HYDROLASE hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 hydrolase#PC00121;lipase#PC00143 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol esterase#P02830 MONDO|Ensembl=ENSMODG00000047600.1|UniProtKB=A0A5F8G3I0 A0A5F8G3I0 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000002244.4|UniProtKB=F7DFF6 F7DFF6 LOC100021696 PTHR19871:SF40 BETA TRANSDUCIN-RELATED PROTEIN TETRATRICOPEPTIDE REPEAT PROTEIN 41-RELATED MONDO|Ensembl=ENSMODG00000006536.4|UniProtKB=F7EWW6 F7EWW6 KLK11 PTHR24271:SF68 KALLIKREIN-RELATED KALLIKREIN-11 catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000012613.4|UniProtKB=A0A5F8HJ28 A0A5F8HJ28 AMPH PTHR46514:SF2 AMPHIPHYSIN AMPHIPHYSIN lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular localization#GO:0051641;vesicle-mediated transport in synapse#GO:0099003;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle endocytosis#GO:0048488;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;cell junction#GO:0030054;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;presynapse#GO:0098793;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000003168.4|UniProtKB=F6WDG4 F6WDG4 COX6A1 PTHR11504:SF4 CYTOCHROME C OXIDASE POLYPEPTIDE VIA CYTOCHROME C OXIDASE SUBUNIT 6A1, MITOCHONDRIAL molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773 catalytic complex#GO:1902494;respiratory chain complex IV#GO:0045277;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidase#PC00175 MONDO|Ensembl=ENSMODG00000015186.3|UniProtKB=F7BW18 F7BW18 PTHR22776:SF10 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 8 regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005203.3|UniProtKB=A0A5F8H860 A0A5F8H860 PTHR11783:SF212 SULFOTRANSFERASE SULT SULFOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000020949.3|UniProtKB=F6SPB3 F6SPB3 HSPA13 PTHR19375:SF169 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN 13 heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787 protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 Hsp70 family chaperone#PC00027;chaperone#PC00072 MONDO|Ensembl=ENSMODG00000005346.4|UniProtKB=F7CHA1 F7CHA1 NIT1 PTHR23088:SF27 NITRILASE-RELATED DEAMINATED GLUTATHIONE AMIDASE hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000007204.4|UniProtKB=F6YWL5 F6YWL5 PTHR15176:SF1 NEPHROCYSTIN NEPHROCYSTIN-1 cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;localization#GO:0051179;non-motile cilium assembly#GO:1905515;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;ciliary base#GO:0097546;membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929 cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000021062.4|UniProtKB=F6ZAW3 F6ZAW3 GART PTHR10520:SF12 TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATED TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3 ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;purine nucleobase metabolic process#GO:0006144;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 De novo purine biosynthesis#P02738>Phosphoribosylamine glycine ligase#P02908 MONDO|Ensembl=ENSMODG00000003984.3|UniProtKB=F7F900 F7F900 PTHR13070:SF0 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34-RELATED TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34 lyase activity#GO:0016829;nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555 endoribonuclease#PC00094;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000025721.2|UniProtKB=A0A5F8HIP3 A0A5F8HIP3 PTHR10500:SF7 BETA-MICROSEMINOPROTEIN MICROSEMINOPROTEIN BETA intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000043815.1|UniProtKB=A0A5F8GHC0 A0A5F8GHC0 PTHR23167:SF82 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000012577.4|UniProtKB=A0A5F8H8U9 A0A5F8H8U9 SRCIN1 PTHR22741:SF5 P140CAP/SNIP-RELATED SRC KINASE SIGNALING INHIBITOR 1 regulation of cell projection organization#GO:0031344;regulation of dendritic spine morphogenesis#GO:0061001;regulation of synapse organization#GO:0050807;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of synapse structure or activity#GO:0050803;regulation of anatomical structure morphogenesis#GO:0022603;regulation of biological quality#GO:0065008;regulation of neuron projection development#GO:0010975;regulation of biological process#GO:0050789;regulation of postsynapse organization#GO:0099175;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007 asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;cell junction#GO:0030054;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000017363.4|UniProtKB=F6VYY4 F6VYY4 AK2 PTHR23359:SF234 NUCLEOTIDE KINASE ADENYLATE KINASE 2, MITOCHONDRIAL transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776 small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;nucleoside diphosphate metabolic process#GO:0009132;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside phosphate biosynthetic process#GO:1901293;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 kinase#PC00137;nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 MONDO|Ensembl=ENSMODG00000003841.2|UniProtKB=A0A5F8GKV6 A0A5F8GKV6 RAB11B PTHR47979:SF41 DRAB11-RELATED RAS-RELATED PROTEIN RAB-11B GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;regulated exocytosis#GO:0045055;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;exocytosis#GO:0006887;secretion by cell#GO:0032940 intracellular organelle#GO:0043229;endosome#GO:0005768;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 G-protein#PC00020;small GTPase#PC00208 PDGF signaling pathway#P00047>Ras#P01154 MONDO|Ensembl=ENSMODG00000001847.5|UniProtKB=F6SPD8 F6SPD8 RNF139 PTHR22763:SF163 RING ZINC FINGER PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF139 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000043831.1|UniProtKB=A0A5F8GIC3 A0A5F8GIC3 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000002933.3|UniProtKB=F6PM94 F6PM94 LOC100018887 PTHR12015:SF101 SMALL INDUCIBLE CYTOKINE A CYTOKINE SCM-1 BETA-RELATED cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;regulation of cell motility#GO:2000145;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326;cytokine-mediated signaling pathway#GO:0019221;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;positive regulation of locomotion#GO:0040017;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;cell migration#GO:0016477;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of cell migration#GO:0030335;response to peptide#GO:1901652;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;cell surface receptor signaling pathway#GO:0007166;taxis#GO:0042330;response to cytokine#GO:0034097;response to chemical#GO:0042221;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 MONDO|Ensembl=ENSMODG00000043824.1|UniProtKB=A0A5F8GCE5 A0A5F8GCE5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013056.4|UniProtKB=F7FQ20 F7FQ20 CCNK PTHR10026:SF144 CYCLIN CYCLIN-K kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription elongation#GO:0032784;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911 kinase activator#PC00138;kinase modulator#PC00140 Cell cycle#P00013>CdkC#P00489 MONDO|Ensembl=ENSMODG00000021433.3|UniProtKB=A0A5F8G431 A0A5F8G431 MPPE1 PTHR13315:SF0 METALLO PHOSPHOESTERASE RELATED METALLOPHOSPHOESTERASE 1 esterase#PC00097;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000020819.4|UniProtKB=F6RMX6 F6RMX6 ETFB PTHR21294:SF8 ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT BETA lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000019471.4|UniProtKB=F6RBD8 F6RBD8 HCK PTHR24418:SF245 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE HCK catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;non-membrane spanning protein tyrosine kinase activity#GO:0004715;binding#GO:0005488;signaling receptor binding#GO:0005102 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular developmental process#GO:0048869;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230 MONDO|Ensembl=ENSMODG00000018839.4|UniProtKB=F7EDV4 F7EDV4 SEMA6C PTHR11036:SF11 SEMAPHORIN SEMAPHORIN-6C molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000017259.4|UniProtKB=F6Q6B3 F6Q6B3 RELN PTHR11841:SF1 REELIN REELIN protein binding#GO:0005515;lipoprotein particle receptor binding#GO:0070325;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular process#GO:0009987;nervous system development#GO:0007399;cell migration#GO:0016477;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neuron migration#GO:0001764;cell motility#GO:0048870;cell differentiation#GO:0030154;central nervous system development#GO:0007417;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;neuron projection#GO:0043005 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000024985.2|UniProtKB=A0A5F8GEM7 A0A5F8GEM7 PTHR24418:SF90 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE YES protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;binding#GO:0005488;non-membrane spanning protein tyrosine kinase activity#GO:0004715;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;cellular developmental process#GO:0048869;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 Cadherin signaling pathway#P00012>Yes#P00476;Parkinson disease#P00049>Src kinase#P01230;CCKR signaling map#P06959>YES1#P07142 MONDO|Ensembl=ENSMODG00000048059.1|UniProtKB=A0A5F8HA24 A0A5F8HA24 PTHR12058:SF0 ARP2/3 COMPLEX 34 KDA SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 2 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;actin polymerization or depolymerization#GO:0008154;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cortical actin cytoskeleton organization#GO:0030866;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;actin filament polymerization#GO:0030041;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;actin cytoskeleton#GO:0015629;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 MONDO|Ensembl=ENSMODG00000049417.1|UniProtKB=A0A5F8HAS4 A0A5F8HAS4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016949.4|UniProtKB=F6V6H7 F6V6H7 C3orf38 PTHR21084:SF1 DENSE INCISORS SIMILAR TO HUMAN CHROMOSOME 3 OPEN READING FRAME 38 MONDO|Ensembl=ENSMODG00000047915.1|UniProtKB=F6VHF0 F6VHF0 LOC100026607 PTHR48018:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004673.3|UniProtKB=F6U716 F6U716 OXTR PTHR24241:SF89 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OXYTOCIN RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;regulation of anatomical structure size#GO:0090066;regulation of system process#GO:0044057;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;response to chemical#GO:0042221;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cell communication#GO:0007154;regulation of biological quality#GO:0065008;circulatory system process#GO:0003013;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Oxytocin receptor mediated signaling pathway#P04391>Oxytocin Receptor#P04531 MONDO|Ensembl=ENSMODG00000012093.4|UniProtKB=F7G4N7 F7G4N7 ASS1 PTHR11587:SF2 ARGININOSUCCINATE SYNTHASE ARGININOSUCCINATE SYNTHASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;biosynthetic process#GO:0009058 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ligase#PC00142;metabolite interconversion enzyme#PC00262 Arginine biosynthesis#P02728>Argininosuccinate synthase#P02840 MONDO|Ensembl=ENSMODG00000020674.4|UniProtKB=F7DLB3 F7DLB3 SLC39A8 PTHR12191:SF2 SOLUTE CARRIER FAMILY 39 METAL CATION SYMPORTER ZIP8 monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;zinc ion transmembrane transporter activity#GO:0005385;bicarbonate transmembrane transporter activity#GO:0015106;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic cation transmembrane transporter activity#GO:0008324;transition metal ion transmembrane transporter activity#GO:0046915;symporter activity#GO:0015293 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;intracellular monoatomic ion homeostasis#GO:0006873;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;import into cell#GO:0098657;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000048687.1|UniProtKB=A0A5F8HK68 A0A5F8HK68 LOC103094100 PTHR23226:SF425 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 24 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002482.4|UniProtKB=A0A5F8HJH2 A0A5F8HJH2 MAEL PTHR21358:SF4 PROTEIN MAELSTROM HOMOLOG PROTEIN MAELSTROM HOMOLOG DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;male meiotic nuclear division#GO:0007140;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;meiotic cell cycle process#GO:1903046;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;gamete generation#GO:0007276;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;nuclear division#GO:0000280;nucleic acid biosynthetic process#GO:0141187;negative regulation of DNA-templated transcription#GO:0045892;RNA metabolic process#GO:0016070;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;male gamete generation#GO:0048232;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;spermatogenesis#GO:0007283;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;meiotic nuclear division#GO:0140013;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;developmental process involved in reproduction#GO:0003006;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;organelle fission#GO:0048285;regulation of DNA-templated transcription#GO:0006355;multicellular organismal reproductive process#GO:0048609;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122 ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000019208.4|UniProtKB=A0A5F8GTR5 A0A5F8GTR5 USO1 PTHR10013:SF7 GENERAL VESICULAR TRANSPORT FACTOR P115 GENERAL VESICULAR TRANSPORT FACTOR P115 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;membrane organization#GO:0061024;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component organization#GO:0016043;membrane fusion#GO:0061025 coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;Golgi stack#GO:0005795;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;vesicle membrane#GO:0012506;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000022856.2|UniProtKB=F6SYG8 F6SYG8 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED RETROVIRAL ENVELOPE PROTEIN GP41-LIKE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013912.4|UniProtKB=F6SVE5 F6SVE5 LOC100010993 PTHR11477:SF1 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 1 transcription regulator activity#GO:0140110;transcription elongation factor activity#GO:0003711 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000007969.4|UniProtKB=F7DQT5 F7DQT5 MRPL19 PTHR15680:SF21 RIBOSOMAL PROTEIN L19 LARGE RIBOSOMAL SUBUNIT PROTEIN BL19M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000000778.5|UniProtKB=F6SSM9 F6SSM9 ZBTB7A PTHR24394:SF14 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 7A DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000021161.4|UniProtKB=A0A5F8G2L8 A0A5F8G2L8 VPS52 PTHR14190:SF16 SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515;syntaxin binding#GO:0019905 retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;endocytic recycling#GO:0032456;cytosolic transport#GO:0016482;lysosomal transport#GO:0007041;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000040304.1|UniProtKB=A0A5F8GER9 A0A5F8GER9 PTHR24379:SF131 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 712 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000003497.4|UniProtKB=F7CRW5 F7CRW5 VCAM1 PTHR13771:SF14 INTERCELLULAR ADHESION MOLECULE VASCULAR CELL ADHESION PROTEIN 1 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cell-cell adhesion#GO:0098609;leukocyte cell-cell adhesion#GO:0007159;cell adhesion#GO:0007155;cell adhesion mediated by integrin#GO:0033627;cellular process#GO:0009987 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000012210.3|UniProtKB=F7CE42 F7CE42 PHB1 PTHR23222:SF0 PROHIBITIN PROHIBITIN 1 MONDO|Ensembl=ENSMODG00000014380.4|UniProtKB=F6T7C8 F6T7C8 ARID1A PTHR12656:SF12 BRG-1 ASSOCIATED FACTOR 250 BAF250 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 1A nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000020045.2|UniProtKB=F6ZH23 F6ZH23 LOC100023806 PTHR48018:SF109 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8U3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045546.1|UniProtKB=H9H6C3 H9H6C3 LOC100616767 PTHR26454:SF59 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014892.4|UniProtKB=F7GGA4 F7GGA4 NR1D2 PTHR24082:SF112 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1 GROUP D MEMBER 2 sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cellular response to hormone stimulus#GO:0032870;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;hormone-mediated signaling pathway#GO:0009755;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000043074.1|UniProtKB=A0A5F8GHR5 A0A5F8GHR5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000011999.3|UniProtKB=F7B911 F7B911 GARRE1 PTHR15703:SF3 RIKEN CDNA 4931406P16 GENE GRANULE ASSOCIATED RAC AND RHOG EFFECTOR PROTEIN 1 binding#GO:0005488;protein-containing complex binding#GO:0044877 intracellular signal transduction#GO:0035556;Rac protein signal transduction#GO:0016601;cell communication#GO:0007154;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000003893.4|UniProtKB=F7D883 F7D883 PTHR19306:SF6 STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6 damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310 site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;site of double-strand break#GO:0035861;nucleus#GO:0005634 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000048969.1|UniProtKB=A0A5F8H878 A0A5F8H878 PTHR16716:SF0 CYTOCHROME C OXIDASE SUBUNIT 7B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 7B, MITOCHONDRIAL transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxidase#PC00175;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000015529.4|UniProtKB=A0A5F8G423 A0A5F8G423 TNS1 PTHR45734:SF3 TENSIN TENSIN-1 cell motility#GO:0048870;cell migration#GO:0016477;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;anchoring junction#GO:0070161 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000011698.2|UniProtKB=F7G3S0 F7G3S0 LOC103100592 PTHR26450:SF416 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004433.4|UniProtKB=F6SV06 F6SV06 FGFRL1 PTHR19890:SF13 FIBROBLAST GROWTH FACTOR RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR-LIKE 1 kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;fibroblast growth factor binding#GO:0017134;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 tyrosine protein kinase receptor#PC00233;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015840.4|UniProtKB=Q2QLA1 Q2QLA1 TES PTHR24211:SF1 LIM DOMAIN-CONTAINING PROTEIN TESTIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000046588.1|UniProtKB=A0A5F8H136 A0A5F8H136 PTHR13390:SF4 LIPASE LIPID DROPLET-ASSOCIATED HYDROLASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 organelle organization#GO:0006996;lipid homeostasis#GO:0055088;cellular component organization#GO:0016043;cellular process#GO:0009987;homeostatic process#GO:0042592;lipid droplet organization#GO:0034389;chemical homeostasis#GO:0048878;cellular component organization or biogenesis#GO:0071840;cholesterol homeostasis#GO:0042632 intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular organelle#GO:0043229 lipase#PC00143;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000011726.4|UniProtKB=F7FSX2 F7FSX2 PTHR10125:SF13 P2X PURINOCEPTOR P2X PURINOCEPTOR 7 monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;signal transduction#GO:0007165;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000010741.4|UniProtKB=H9H6E9 H9H6E9 DDX50 PTHR47958:SF88 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX50 macromolecular conformation isomerase activity#GO:0120543;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000041051.1|UniProtKB=A0A5F8H3E8 A0A5F8H3E8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000021051.3|UniProtKB=F6VJM7 F6VJM7 RUNX1 PTHR11950:SF40 RUNT RELATED RUNT-RELATED TRANSCRIPTION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 nervous system development#GO:0007399;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell development#GO:0048468;regulation of biological process#GO:0050789;skeletal system development#GO:0001501;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;chondrocyte differentiation#GO:0002062;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;hemopoiesis#GO:0030097;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;connective tissue development#GO:0061448;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;ossification#GO:0001503;regulation of developmental process#GO:0050793;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;cartilage development#GO:0051216 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;Runt transcription factor#PC00254 MONDO|Ensembl=ENSMODG00000011719.3|UniProtKB=F7FT43 F7FT43 DRP2 PTHR12268:SF16 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROPHIN-RELATED PROTEIN 2 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808 cell projection#GO:0042995;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000049480.1|UniProtKB=F7ASF4 F7ASF4 LOC100014318 PTHR26453:SF237 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2C1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000050232.1|UniProtKB=A0A5F8H1X9 A0A5F8H1X9 LOC100028416 PTHR48002:SF97 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014334.3|UniProtKB=F6UMG5 F6UMG5 AVPR1A PTHR24241:SF17 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR VASOPRESSIN V1A RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089 regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;system process#GO:0003008;regulation of anatomical structure size#GO:0090066;regulation of system process#GO:0044057;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of biological quality#GO:0065008;cell communication#GO:0007154;circulatory system process#GO:0003013;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019880.4|UniProtKB=H9H7J3 H9H7J3 PTHR24147:SF53 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN 26 MONDO|Ensembl=ENSMODG00000042548.1|UniProtKB=A0A5F8GLN7 A0A5F8GLN7 SMIM8 PTHR14274:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 8 SMALL INTEGRAL MEMBRANE PROTEIN 8 MONDO|Ensembl=ENSMODG00000018498.4|UniProtKB=F7BQX3 F7BQX3 SLCO2A1 PTHR11388:SF14 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2A1 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;lipid localization#GO:0010876 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transporter#PC00227 MONDO|Ensembl=ENSMODG00000013851.3|UniProtKB=A0A5F8GZ04 A0A5F8GZ04 EIF4H PTHR23236:SF120 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4H nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000010542.4|UniProtKB=F6ZET6 F6ZET6 SMNDC1 PTHR13681:SF26 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000012324.3|UniProtKB=F7E2Y5 F7E2Y5 HESX1 PTHR46966:SF1 HOMEOBOX EXPRESSED IN ES CELLS 1 HOMEOBOX EXPRESSED IN ES CELLS 1 sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677 developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;head development#GO:0060322;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of cellular process#GO:0050794;forebrain development#GO:0030900 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000005038.3|UniProtKB=A0A5F8G3K7 A0A5F8G3K7 NECAB2 PTHR12178:SF2 EF-HAND DOMAIN-CONTAINING PROTEIN N-TERMINAL EF-HAND CALCIUM-BINDING PROTEIN 2 regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000011325.4|UniProtKB=F6WII6 F6WII6 HBE1 PTHR11442:SF7 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT BETA-RELATED tetrapyrrole binding#GO:0046906;binding#GO:0005488;molecular carrier activity#GO:0140104;heme binding#GO:0020037 localization#GO:0051179;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;homeostasis of number of cells#GO:0048872;immune system process#GO:0002376;homeostatic process#GO:0042592;cell development#GO:0048468;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;multicellular organismal-level homeostasis#GO:0048871;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;developmental process#GO:0032502;transport#GO:0006810;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;cellular process#GO:0009987 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219;globin#PC00107 MONDO|Ensembl=ENSMODG00000012660.5|UniProtKB=F6VYB3 F6VYB3 NR4A3 PTHR24085:SF2 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 3 DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;nuclear receptor binding#GO:0016922;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;transcription factor binding#GO:0008134 regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;regulation of macromolecule biosynthetic process#GO:0010556;response to hormone#GO:0009725;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000001419.5|UniProtKB=F6ZZ08 F6ZZ08 PTHR11829:SF156 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN E3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000046405.1|UniProtKB=A0A5F8HFR7 A0A5F8HFR7 NUDT17 PTHR42904:SF1 NUDIX HYDROLASE, NUDC SUBFAMILY M7GPPPN-MRNA HYDROLASE NUDT17 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;NADP+ metabolic process#GO:0006739;NAD+ metabolic process#GO:0019674;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;pyridine nucleotide catabolic process#GO:0019364;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524 microbody#GO:0042579;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000017456.4|UniProtKB=F6Z5S0 F6Z5S0 LMNTD1 PTHR47012:SF1 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 1 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000042294.1|UniProtKB=A0A5F8GCG4 A0A5F8GCG4 LRAT PTHR46678:SF1 LECITHIN RETINOL ACYLTRANSFERASE LECITHIN RETINOL ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 terpenoid metabolic process#GO:0006721;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;cellular process#GO:0009987;biological regulation#GO:0065007;hormone metabolic process#GO:0042445 rough endoplasmic reticulum#GO:0005791;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000045877.1|UniProtKB=A0A5F8HCW5 A0A5F8HCW5 PPP1R27 PTHR46899:SF4 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 27 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 27 binding#GO:0005488;phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515 phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000003136.4|UniProtKB=F6WUX5 F6WUX5 IFI30 PTHR13234:SF81 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000009675.3|UniProtKB=F6SH43 F6SH43 RAB15 PTHR47980:SF4 LD44762P RAS-RELATED PROTEIN RAB-15 vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;exocytosis#GO:0006887;secretion by cell#GO:0032940;transport#GO:0006810 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 MONDO|Ensembl=ENSMODG00000013336.4|UniProtKB=A0A5F8GJG0 A0A5F8GJG0 LOC100029998 PTHR10728:SF39 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 GAMMA phospholipid binding#GO:0005543;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;cation binding#GO:0043169;ion binding#GO:0043167;lipase activity#GO:0016298;small molecule binding#GO:0036094;carboxylic ester hydrolase activity#GO:0052689;A2-type glycerophospholipase activity#GO:0004623;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;metal ion binding#GO:0046872;lipid binding#GO:0008289;binding#GO:0005488;calcium ion binding#GO:0005509 glycerolipid catabolic process#GO:0046503;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042;catabolic process#GO:0009056;glycerophospholipid metabolic process#GO:0006650;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;organelle envelope#GO:0031967;endomembrane system#GO:0012505;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;nucleus#GO:0005634 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;Angiogenesis#P00005>cPLA2#P00251 MONDO|Ensembl=ENSMODG00000008008.2|UniProtKB=F7CLG9 F7CLG9 TMEM223 PTHR14549:SF2 TRANSMEMBRANE PROTEIN 223 TRANSMEMBRANE PROTEIN 223 MONDO|Ensembl=ENSMODG00000006182.4|UniProtKB=F7AI84 F7AI84 ROGDI PTHR13618:SF1 LEUCINE ZIPPER CONTAINING TRANSCRIPTION FACTOR LZF1 PROTEIN ROGDI HOMOLOG protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 MONDO|Ensembl=ENSMODG00000046877.1|UniProtKB=A0A5F8GWM9 A0A5F8GWM9 SPOCK1 PTHR13866:SF17 SPARC OSTEONECTIN TESTICAN-1 molecular function inhibitor activity#GO:0140678;cation binding#GO:0043169;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;calcium ion binding#GO:0005509;binding#GO:0005488;peptidase inhibitor activity#GO:0030414;small molecule binding#GO:0036094;endopeptidase regulator activity#GO:0061135;ion binding#GO:0043167;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000006093.4|UniProtKB=F7F135 F7F135 RPS6KL1 PTHR15508:SF4 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE-LIKE 1 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142 MONDO|Ensembl=ENSMODG00000003482.4|UniProtKB=F7FBA9 F7FBA9 PTHR24376:SF85 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 600-RELATED negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000041004.1|UniProtKB=A0A5F8H5H9 A0A5F8H5H9 LOC100015240 PTHR23147:SF233 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN 4 rhythmic process#GO:0048511;circadian rhythm#GO:0007623 membraneless organelle#GO:0043228;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000037483.1|UniProtKB=A0A5F8H6M4 A0A5F8H6M4 SAMD10 PTHR20843:SF1 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 10 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 10 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000042768.1|UniProtKB=A0A5F8HD01 A0A5F8HD01 LOC100017002 PTHR48001:SF125 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1B1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017325.4|UniProtKB=F6WWH0 F6WWH0 TRAF2 PTHR10131:SF21 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 2 catalytic activity, acting on a protein#GO:0140096;tumor necrosis factor receptor superfamily binding#GO:0032813;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;acyltransferase activity#GO:0016746;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like protein transferase activity#GO:0019787 regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;response to peptide#GO:1901652;tumor necrosis factor-mediated signaling pathway#GO:0033209;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cytokine-mediated signaling pathway#GO:0019221;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;response to tumor necrosis factor#GO:0034612;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 p53 pathway#P00059>TRAF#P04620;Apoptosis signaling pathway#P00006>TRAF2#P00306 MONDO|Ensembl=ENSMODG00000047084.1|UniProtKB=A0A5F8GV40 A0A5F8GV40 PTHR14340:SF21 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 IG-LIKE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000012542.4|UniProtKB=F6PYX9 F6PYX9 LOC100024593 PTHR11461:SF145 SERINE PROTEASE INHIBITOR, SERPIN SERPIN A3-5 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000011477.3|UniProtKB=F6VJY8 F6VJY8 LOC100022937 PTHR26450:SF63 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52Z1P olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012284.4|UniProtKB=A0A5F8GFA5 A0A5F8GFA5 CFH PTHR45785:SF7 COMPLEMENT FACTOR H-RELATED COMPLEMENT FACTOR H protein binding#GO:0005515;complement binding#GO:0001848;binding#GO:0005488 immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;humoral immune response#GO:0006959;positive regulation of immune response#GO:0050778;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;positive regulation of immune system process#GO:0002684;immune response#GO:0006955;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;complement activation#GO:0006956;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 complement component#PC00078 MONDO|Ensembl=ENSMODG00000029249.2|UniProtKB=A0A5F8GQ41 A0A5F8GQ41 SLC4A11 PTHR11453:SF127 ANION EXCHANGE PROTEIN SOLUTE CARRIER FAMILY 4 MEMBER 11 bicarbonate transmembrane transporter activity#GO:0015106;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;homeostatic process#GO:0042592;transport#GO:0006810;chemical homeostasis#GO:0048878;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000015269.4|UniProtKB=F6TML6 F6TML6 PRKAB1 PTHR10343:SF96 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1 protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 MONDO|Ensembl=ENSMODG00000007436.3|UniProtKB=F7DWK0 F7DWK0 RBM12B PTHR13976:SF28 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED RNA-BINDING PROTEIN 12B binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000015519.4|UniProtKB=F6VYM2 F6VYM2 PTHR10183:SF333 CALPAIN CALPAIN-13 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000003021.3|UniProtKB=F6Q2N1 F6Q2N1 UNC119B PTHR12951:SF3 RETINAL PROTEIN 4 PROTEIN UNC-119 HOMOLOG B lipid binding#GO:0008289;binding#GO:0005488 cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle assembly#GO:0070925;localization#GO:0051179;cilium organization#GO:0044782;protein transport#GO:0015031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cell projection assembly#GO:0030031;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000009015.4|UniProtKB=F7BPP6 F7BPP6 PDX1 PTHR45664:SF12 PROTEIN ZERKNUELLT 1-RELATED PANCREAS_DUODENUM HOMEOBOX PROTEIN 1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;cellular developmental process#GO:0048869;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;pancreas development#GO:0031016;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000009623.4|UniProtKB=F6REP0 F6REP0 ANKRD13B PTHR12447:SF3 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13B protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;biological regulation#GO:0065007;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013969.3|UniProtKB=F6R6Z7 F6R6Z7 PTHR23267:SF483 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-25 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000008743.4|UniProtKB=A0A5F8HFW9 A0A5F8HFW9 DHX57 PTHR18934:SF145 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX57-RELATED helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000004575.4|UniProtKB=F6R4A2 F6R4A2 ATRN PTHR24044:SF495 NOTCH LIGAND FAMILY MEMBER ATTRACTIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000002411.4|UniProtKB=F7EH65 F7EH65 PTHR11461:SF34 SERINE PROTEASE INHIBITOR, SERPIN CORTICOSTEROID-BINDING GLOBULIN enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000044911.1|UniProtKB=A0A5F8GBC3 A0A5F8GBC3 COA5 PTHR28627:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5 cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000046778.1|UniProtKB=A0A5F8HCX6 A0A5F8HCX6 SNRPD3 PTHR23338:SF17 SMALL NUCLEAR RIBONUCLEOPROTEIN SM SMALL NUCLEAR RIBONUCLEOPROTEIN SM D3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613 spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;U2-type spliceosomal complex#GO:0005684;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;cytoplasm#GO:0005737;U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U5 snRNP#GO:0005682 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000025696.3|UniProtKB=F6TJH7 F6TJH7 COPRS PTHR36461:SF1 COORDINATOR OF PRMT5 AND DIFFERENTIATION STIMULATOR COORDINATOR OF PRMT5 AND DIFFERENTIATION STIMULATOR protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000015933.3|UniProtKB=F6ZQK1 F6ZQK1 MRPS18B PTHR13329:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S18B SMALL RIBOSOMAL SUBUNIT PROTEIN MS40 membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000011124.4|UniProtKB=F7BB81 F7BB81 DSC3 PTHR24025:SF0 DESMOGLEIN FAMILY MEMBER DESMOCOLLIN-2 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161 cadherin#PC00057 MONDO|Ensembl=ENSMODG00000046230.1|UniProtKB=A0A5F8GW59 A0A5F8GW59 LARP6 PTHR22792:SF71 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 6 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000014280.4|UniProtKB=F6X0P6 F6X0P6 CYLC1 PTHR16742:SF2 CYCLICIN CYLICIN-2 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000005298.4|UniProtKB=F7AFV1 F7AFV1 CPXM1 PTHR11532:SF43 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE X1-RELATED carboxypeptidase activity#GO:0004180;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824 cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;proteolysis#GO:0006508;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 MONDO|Ensembl=ENSMODG00000019010.2|UniProtKB=F7C606 F7C606 DCTN6 PTHR13072:SF0 DYNACTIN 6 DYNACTIN SUBUNIT 6 binding#GO:0005488;protein-containing complex binding#GO:0044877 mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cellular process#GO:0009987;cell cycle process#GO:0022402;organelle organization#GO:0006996;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000011793.4|UniProtKB=F7ALJ3 F7ALJ3 HMCN2 PTHR23277:SF107 NECTIN-RELATED HEMICENTIN-1 cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;extracellular matrix#GO:0031012;membrane#GO:0016020;external encapsulating structure#GO:0030312;cell periphery#GO:0071944;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912;extracellular region#GO:0005576 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000003723.3|UniProtKB=F7EW90 F7EW90 SPA17 PTHR10699:SF16 NEUROMODULIN SPERM SURFACE PROTEIN SP17 calmodulin binding#GO:0005516;binding#GO:0005488;protein binding#GO:0005515 cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;sperm principal piece#GO:0097228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;9+2 motile cilium#GO:0097729 MONDO|Ensembl=ENSMODG00000003581.3|UniProtKB=F7FQA5 F7FQA5 RBM43 PTHR15225:SF8 INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN RNA-BINDING PROTEIN 43 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000024756.3|UniProtKB=A0A5F8HKD2 A0A5F8HKD2 ANKUB1 PTHR46885:SF1 PROTEIN ANKUB1 PROTEIN ANKUB1 MONDO|Ensembl=ENSMODG00000042897.1|UniProtKB=A0A5F8HF25 A0A5F8HF25 IL15RA PTHR15060:SF0 INTERLEUKIN-15 RECEPTOR SUBUNIT ALPHA INTERLEUKIN-15 RECEPTOR SUBUNIT ALPHA transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 cell surface receptor signaling pathway#GO:0007166;interleukin-15-mediated signaling pathway#GO:0035723;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to peptide#GO:1901652;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 MONDO|Ensembl=ENSMODG00000015114.4|UniProtKB=F7C9G9 F7C9G9 PTHR24216:SF11 PAXILLIN-RELATED PAXILLIN protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 transforming growth factor beta receptor signaling pathway#GO:0007179;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cell migration#GO:0016477;endothelial cell migration#GO:0043542;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;substrate adhesion-dependent cell spreading#GO:0034446;cell surface receptor signaling pathway#GO:0007166;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;signaling#GO:0023052;cell adhesion#GO:0007155;response to transforming growth factor beta#GO:0071559;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363 cell-cell junction#GO:0005911;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Paxillin#P00950;Gonadotropin-releasing hormone receptor pathway#P06664>Paxillin#P06784;CCKR signaling map#P06959>Paxillin#P07145;Angiogenesis#P00005>Paxillin#P00194;VEGF signaling pathway#P00056>Paxillin#P01418 MONDO|Ensembl=ENSMODG00000019802.4|UniProtKB=H9H7G9 H9H7G9 SLC25A14 PTHR45618:SF20 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED BRAIN MITOCHONDRIAL CARRIER PROTEIN 1 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;chloride transmembrane transporter activity#GO:0015108;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509 regulation of response to stress#GO:0080134;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cellular response to stress#GO:0080135;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000011787.4|UniProtKB=A0A5F8GUN7 A0A5F8GUN7 EVI5 PTHR22957:SF679 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN ECOTROPIC VIRAL INTEGRATION SITE 5 PROTEIN HOMOLOG enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000002588.4|UniProtKB=F7G527 F7G527 ECRG4 PTHR31613:SF2 AUGURIN AUGURIN regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;system development#GO:0048731;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;cell cycle#GO:0007049;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;developmental process#GO:0032502;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;response to stimulus#GO:0050896;central nervous system development#GO:0007417;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;multicellular organism development#GO:0007275;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;nervous system development#GO:0007399;response to stress#GO:0006950;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000025325.2|UniProtKB=F7E715 F7E715 LOC100011252 PTHR23122:SF45 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PROTEIN PALS2 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004933.4|UniProtKB=F7AUF7 F7AUF7 PTHR24253:SF146 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 12 catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000011909.4|UniProtKB=A0A5F8G1U9 A0A5F8G1U9 MANF PTHR12990:SF10 ARMET-LIKE PROTEIN MESENCEPHALIC ASTROCYTE-DERIVED NEUROTROPHIC FACTOR signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000048473.1|UniProtKB=F7CAH7 F7CAH7 LOC100022736 PTHR26452:SF930 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000036377.1|UniProtKB=A0A5F8G5X6 A0A5F8G5X6 PTHR19965:SF22 RNA AND EXPORT FACTOR BINDING PROTEIN CHROMATIN TARGET OF PRMT1-LIKE 1 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;biosynthetic process#GO:0009058;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000039030.1|UniProtKB=A0A5F8HBS0 A0A5F8HBS0 LOC103104742 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019873.3|UniProtKB=F6RQR2 F6RQR2 TP53I11 PTHR31584:SF1 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 11 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 11 MONDO|Ensembl=ENSMODG00000016077.4|UniProtKB=F7G9G8 F7G9G8 RPS2 PTHR13718:SF4 RIBOSOMAL S SUBUNIT SMALL RIBOSOMAL SUBUNIT PROTEIN US5 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000013389.4|UniProtKB=F7D8D3 F7D8D3 BBS2 PTHR32465:SF0 BARDET-BIEDL SYNDROME 2 PROTEIN BBSOME COMPLEX MEMBER BBS2 cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;BBSome#GO:0034464;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000023899.1|UniProtKB=F7D710 F7D710 LOC103103239 PTHR33505:SF4 ZGC:162634 PROTEIN PREY, MITOCHONDRIAL MONDO|Ensembl=ENSMODG00000046331.1|UniProtKB=A0A5F8GVM7 A0A5F8GVM7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024048.3|UniProtKB=A0A5F8GY94 A0A5F8GY94 SPATA7 PTHR14917:SF2 SPERMATOGENESIS-ASSOCIATED PROTEIN 7 SPERMATOGENESIS-ASSOCIATED PROTEIN 7 homeostatic process#GO:0042592;cytoskeleton organization#GO:0007010;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;tissue homeostasis#GO:0001894;microtubule-based process#GO:0007017;multicellular organismal-level homeostasis#GO:0048871;cellular component organization or biogenesis#GO:0071840;retina homeostasis#GO:0001895;microtubule cytoskeleton organization#GO:0000226 axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;ciliary transition zone#GO:0035869;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;9+0 non-motile cilium#GO:0097731;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733 MONDO|Ensembl=ENSMODG00000045776.1|UniProtKB=F6PQP3 F6PQP3 PTHR18847:SF0 20 KD NUCLEAR CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 gene expression#GO:0010467;RNA processing#GO:0006396;mRNA processing#GO:0006397;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule localization#GO:0033036;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;RNA export from nucleus#GO:0006405;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;transport#GO:0006810;RNA transport#GO:0050658;RNA localization#GO:0006403;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;nucleobase-containing compound transport#GO:0015931;regulation of macromolecule metabolic process#GO:0060255;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleic acid transport#GO:0050657;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;RNA splicing, via transesterification reactions#GO:0000375;nucleocytoplasmic transport#GO:0006913 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000018401.5|UniProtKB=F6Q9K6 F6Q9K6 WNK1 PTHR13902:SF46 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK1 channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;protein serine/threonine kinase activity#GO:0004674;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106 negative regulation of transport#GO:0051051;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;chemical homeostasis#GO:0048878 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000043501.1|UniProtKB=A0A5F8HBA1 A0A5F8HBA1 PTHR23349:SF40 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST BHLH DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000009597.4|UniProtKB=F6RQM4 F6RQM4 SUN2 PTHR12911:SF22 SAD1/UNC-84-LIKE PROTEIN-RELATED SUN DOMAIN-CONTAINING PROTEIN 2 protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;membrane#GO:0016020;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000010085.6|UniProtKB=F6XMB7 F6XMB7 SUPT20H PTHR13526:SF8 TRANSCRIPTION FACTOR SPT20 HOMOLOG SPT20 HOMOLOG, SAGA COMPLEX COMPONENT-RELATED transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;SAGA-type complex#GO:0070461;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000036516.1|UniProtKB=A0A5F8HCE3 A0A5F8HCE3 PTHR23267:SF313 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 5-2 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000017460.2|UniProtKB=F6Z5M0 F6Z5M0 ETFRF1 PTHR21024:SF0 GROWTH HORMONE-INDUCIBLE SOLUBLE PROTEIN-RELATED ELECTRON TRANSFER FLAVOPROTEIN REGULATORY FACTOR 1 negative regulation of metabolic process#GO:0009892;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of metabolic process#GO:0019222;negative regulation of cellular process#GO:0048523 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000047226.1|UniProtKB=A0A5F8GEK2 A0A5F8GEK2 OTX2 PTHR45793:SF2 HOMEOBOX PROTEIN HOMEOBOX PROTEIN OTX2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000016379.4|UniProtKB=H9H6U3 H9H6U3 HSPBP1 PTHR19316:SF18 PROTEIN FOLDING REGULATOR HSP70-BINDING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000025488.3|UniProtKB=F6QYU2 F6QYU2 ZBBX PTHR28634:SF1 ZINC FINGER B-BOX DOMAIN-CONTAINING PROTEIN 1 ZINC FINGER B-BOX DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000028324.2|UniProtKB=K7E0D5 K7E0D5 C3H6orf52 PTHR37457:SF1 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED SIMILAR TO HUMAN CHROMOSOME 6 OPEN READING FRAME 52 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;tRNA binding#GO:0000049 post-transcriptional regulation of gene expression#GO:0010608;metabolic process#GO:0008152;translational elongation#GO:0006414;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;translation#GO:0006412;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000002555.4|UniProtKB=F7GFD6 F7GFD6 NUP37 PTHR22806:SF0 NUCLEOPORIN NUP37 P37 -RELATED NUCLEOPORIN NUP37 nucleus#GO:0005634;nuclear pore outer ring#GO:0031080;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513 transporter#PC00227 MONDO|Ensembl=ENSMODG00000007536.4|UniProtKB=K7E435 K7E435 ITGB1 PTHR10082:SF28 INTEGRIN BETA SUBUNIT INTEGRIN BETA-1 cytokine binding#GO:0019955;integrin binding#GO:0005178;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;extracellular matrix binding#GO:0050840;protein kinase binding#GO:0019901;laminin binding#GO:0043236;enzyme binding#GO:0019899;collagen binding#GO:0005518;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;binding#GO:0005488 biological regulation#GO:0065007;cell migration#GO:0016477;cellular process#GO:0009987;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609;cell surface receptor signaling pathway#GO:0007166;cell adhesion mediated by integrin#GO:0033627;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cell surface#GO:0009986;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;cell junction#GO:0030054;membrane protein complex#GO:0098796;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;synapse#GO:0045202;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;integrin complex#GO:0008305;anchoring junction#GO:0070161 integrin#PC00126 CCKR signaling map#P06959>ITGB1#P07113;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853;Integrin signalling pathway#P00034>Integrin beta#P00931;CCKR signaling map#P06959>ITGB1#G06984;CCKR signaling map#P06959>ITGB1#G07277;Gonadotropin-releasing hormone receptor pathway#P06664>alpha-beta integrin dimer#P06820 MONDO|Ensembl=ENSMODG00000013491.4|UniProtKB=F7F8S8 F7F8S8 UBE4A PTHR13931:SF16 UBIQUITINATION FACTOR E4 UBIQUITIN CONJUGATION FACTOR E4 A acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000018603.4|UniProtKB=F7BQ15 F7BQ15 RBP1 PTHR11955:SF56 FATTY ACID BINDING PROTEIN RETINOL-BINDING PROTEIN 1 alcohol binding#GO:0043178;fatty acid binding#GO:0005504;lipid binding#GO:0008289;binding#GO:0005488;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;ion binding#GO:0043167;organic acid binding#GO:0043177 monocarboxylic acid transport#GO:0015718;localization#GO:0051179;fatty acid transport#GO:0015908;establishment of localization#GO:0051234;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000012224.3|UniProtKB=F6Z6T1 F6Z6T1 PTHR22591:SF2 XIN XIN ACTIN-BINDING REPEAT-CONTAINING PROTEIN 1 binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;actin filament bundle#GO:0032432;membraneless organelle#GO:0043228;cell junction#GO:0030054;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;stress fiber#GO:0001725;cell-substrate junction#GO:0030055;intracellular membraneless organelle#GO:0043232;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actomyosin#GO:0042641;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000015900.4|UniProtKB=F7AFZ2 F7AFZ2 PTHR17920:SF3 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 MONDO|Ensembl=ENSMODG00000048280.1|UniProtKB=A0A5F8G4Z9 A0A5F8G4Z9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000029107.2|UniProtKB=A0A5F8H8U4 A0A5F8H8U4 LRRC63 PTHR48051:SF62 FAMILY NOT NAMED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 57 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000027828.2|UniProtKB=K7DYU9 K7DYU9 PTHR35825:SF2 CASEIN KINASE II SUBUNIT ALPHA PRIME-INTERACTING PROTEIN CASEIN KINASE II SUBUNIT ALPHA'-INTERACTING PROTEIN MONDO|Ensembl=ENSMODG00000001136.4|UniProtKB=F7D4R4 F7D4R4 MND1 PTHR31398:SF0 MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;sexual reproduction#GO:0019953;organelle fission#GO:0048285;cellular component organization#GO:0016043;meiosis I#GO:0007127;primary metabolic process#GO:0044238;meiotic cell cycle process#GO:1903046;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cell cycle process#GO:0022402;reciprocal homologous recombination#GO:0140527;reproductive process#GO:0022414;homologous recombination#GO:0035825 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000015400.4|UniProtKB=F6T4Z5 F6T4Z5 RNFT2 PTHR15860:SF2 UNCHARACTERIZED RING FINGER-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNFT2 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 MONDO|Ensembl=ENSMODG00000047076.1|UniProtKB=K7E3X2 K7E3X2 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000015960.4|UniProtKB=F6UX07 F6UX07 PTHR10970:SF1 CLUSTERIN CLUSTERIN protein binding#GO:0005515;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of programmed cell death#GO:0043067;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of metabolic process#GO:0009893;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of protein metabolic process#GO:0051247;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of apoptotic process#GO:0042981;regulation of ubiquitin-dependent protein catabolic process#GO:2000058 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 CCKR signaling map#P06959>CLU#P07069;CCKR signaling map#P06959>CLU#G07284;CCKR signaling map#P06959>CLU#G06991 MONDO|Ensembl=ENSMODG00000014727.4|UniProtKB=F6ZCS7 F6ZCS7 PTHR24028:SF46 CADHERIN-87A PROTOCADHERIN-8 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000017056.4|UniProtKB=F6XHV5 F6XHV5 SDC3 PTHR10915:SF7 SYNDECAN SYNDECAN-3 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017398.4|UniProtKB=F6SKT0 F6SKT0 HEBP2 PTHR11220:SF70 HEME-BINDING PROTEIN-RELATED HEME-BINDING PROTEIN 2 tetrapyrrole binding#GO:0046906;binding#GO:0005488;heme binding#GO:0020037 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000017169.4|UniProtKB=F6QD55 F6QD55 GSAP PTHR13630:SF1 GAMMA-SECRETASE-ACTIVATING PROTEIN GAMMA-SECRETASE-ACTIVATING PROTEIN positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of macromolecule metabolic process#GO:0010604;regulation of macromolecule metabolic process#GO:0060255;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000040611.1|UniProtKB=A0A5F8H960 A0A5F8H960 SH2D5 PTHR15832:SF3 SHC (SRC HOMOLOGY DOMAIN C-TERMINAL) ADAPTOR HOMOLOG SH2 DOMAIN-CONTAINING PROTEIN 5 postsynaptic density#GO:0014069;cell junction#GO:0030054;postsynapse#GO:0098794;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000003676.4|UniProtKB=F7FAN2 F7FAN2 SASS6 PTHR44281:SF4 SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG gamete generation#GO:0007276;reproductive process#GO:0022414;membraneless organelle assembly#GO:0140694;developmental process involved in reproduction#GO:0003006;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;centriole replication#GO:0007099;sexual reproduction#GO:0019953;male gamete generation#GO:0048232;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;microtubule organizing center organization#GO:0031023;developmental process#GO:0032502;spermatogenesis#GO:0007283 intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000017582.4|UniProtKB=F7B5A9 F7B5A9 KCNQ4 PTHR47735:SF7 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873 cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241;transporter#PC00227 MONDO|Ensembl=ENSMODG00000013514.4|UniProtKB=F7D784 F7D784 PTHR10570:SF9 T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN / DELTA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cellular developmental process#GO:0048869;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;T cell differentiation#GO:0030217;hemopoiesis#GO:0030097;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;lymphocyte differentiation#GO:0030098;cell activation#GO:0001775;immune system process#GO:0002376;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;mononuclear cell differentiation#GO:1903131;leukocyte activation#GO:0045321;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 signaling receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>CD3 eta#P01302 MONDO|Ensembl=ENSMODG00000007405.4|UniProtKB=F6YYK0 F6YYK0 TMEM94 PTHR13219:SF6 TRANSMEMBRANE PROTEIN 94 TRANSMEMBRANE PROTEIN 94 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;magnesium ion transmembrane transporter activity#GO:0015095;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular localization#GO:0051641;transport#GO:0006810;magnesium ion transport#GO:0015693;intracellular transport#GO:0046907;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000011263.4|UniProtKB=F6R183 F6R183 KIF18B PTHR24115:SF414 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF18B macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515 cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;protein depolymerization#GO:0051261;chromosome localization#GO:0050000;cytoskeleton organization#GO:0007010;microtubule depolymerization#GO:0007019;chromosome segregation#GO:0007059;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle#GO:0007049;protein-containing complex disassembly#GO:0032984;microtubule-based movement#GO:0007018;mitotic cell cycle#GO:0000278;nuclear division#GO:0000280;organelle localization#GO:0051640;supramolecular fiber organization#GO:0097435;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;cellular component disassembly#GO:0022411;localization#GO:0051179 microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoplasmic microtubule#GO:0005881;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;intracellular organelle#GO:0043229;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000012475.4|UniProtKB=A0A5F8GYH0 A0A5F8GYH0 KMT5A PTHR46167:SF1 N-LYSINE METHYLTRANSFERASE KMT5A N-LYSINE METHYLTRANSFERASE KMT5A catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;chromosome organization#GO:0051276;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000009895.4|UniProtKB=F6VCA2 F6VCA2 ARHGEF37 PTHR22834:SF9 NUCLEAR FUSION PROTEIN FUS2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 37 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000010055.4|UniProtKB=F6Y554 F6Y554 LOC100029348 PTHR24115:SF549 KINESIN-RELATED KINESIN-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein binding#GO:0005515;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000038285.1|UniProtKB=K7DZ03 K7DZ03 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000007904.4|UniProtKB=F6YSH6 F6YSH6 LOC103106290 PTHR48001:SF27 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018225.3|UniProtKB=F6PGI2 F6PGI2 CDKN1B PTHR10265:SF9 CYCLIN-DEPENDENT KINASE INHIBITOR 1 CYCLIN-DEPENDENT KINASE INHIBITOR 1B cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme inhibitor activity#GO:0004857;kinase inhibitor activity#GO:0019210;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle#GO:0007346;negative regulation of mitotic cell cycle phase transition#GO:1901991;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 kinase inhibitor#PC00139;kinase modulator#PC00140 Interleukin signaling pathway#P00036>p27KIP1#P00982 MONDO|Ensembl=ENSMODG00000014999.4|UniProtKB=F6RH94 F6RH94 NFIB PTHR11492:SF4 NUCLEAR FACTOR I NUCLEAR FACTOR 1 B-TYPE cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000013739.4|UniProtKB=F6X8A8 F6X8A8 PCSK7 PTHR42884:SF28 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 7 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 serine protease#PC00203 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 MONDO|Ensembl=ENSMODG00000013052.4|UniProtKB=F7G0V6 F7G0V6 XPNPEP3 PTHR43226:SF4 XAA-PRO AMINOPEPTIDASE 3 XAA-PRO AMINOPEPTIDASE 3 peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000014736.4|UniProtKB=F6ZC55 F6ZC55 PLCL2 PTHR10336:SF84 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN INACTIVE PHOSPHOLIPASE C-LIKE PROTEIN 2 lipase activity#GO:0016298;hydrolase activity#GO:0016787;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081 regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;signaling#GO:0023052;cell-cell signaling#GO:0007267;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;cell communication#GO:0007154 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262;phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412 MONDO|Ensembl=ENSMODG00000002829.4|UniProtKB=F7EIW6 F7EIW6 GCC2 PTHR18902:SF25 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000021102.4|UniProtKB=F6UI01 F6UI01 BCOR PTHR24117:SF8 AGAP007537-PB BCL-6 COREPRESSOR transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000017482.3|UniProtKB=F7FEY8 F7FEY8 PTHR10880:SF48 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;chromatin#GO:0000785;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000013282.4|UniProtKB=F7A9X6 F7A9X6 RYR1 PTHR46399:SF10 B30.2/SPRY DOMAIN-CONTAINING PROTEIN RYANODINE RECEPTOR 1 ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873 multicellular organismal process#GO:0032501;release of sequestered calcium ion into cytosol by sarcoplasmic reticulum#GO:0014808;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;system process#GO:0003008;transport#GO:0006810;muscle contraction#GO:0006936;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;calcium ion transmembrane transport#GO:0070588;muscle system process#GO:0003012;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;sarcoplasm#GO:0016528;endoplasmic reticulum subcompartment#GO:0098827;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;Z disc#GO:0030018;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;endomembrane system#GO:0012505;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789;I band#GO:0031674;sarcolemma#GO:0042383;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;calcium channel complex#GO:0034704;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;myofibril#GO:0030016;organelle subcompartment#GO:0031984;supramolecular fiber#GO:0099512;contractile muscle fiber#GO:0043292;sarcoplasmic reticulum#GO:0016529;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;sarcoplasmic reticulum membrane#GO:0033017;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cation channel complex#GO:0034703;endoplasmic reticulum#GO:0005783;sarcomere#GO:0030017;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588 Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441;CCKR signaling map#P06959>RYR1/2/3#P07088 MONDO|Ensembl=ENSMODG00000005573.4|UniProtKB=F7F3A6 F7F3A6 PSMB1 PTHR32194:SF2 METALLOPROTEASE TLDD PROTEASOME SUBUNIT BETA TYPE-1 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;proteasome complex#GO:0000502 metalloprotease#PC00153 Parkinson disease#P00049>20S proteasome#P01227 MONDO|Ensembl=ENSMODG00000008960.5|UniProtKB=A0A5F8HEQ7 A0A5F8HEQ7 TNRC6B PTHR13020:SF32 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6B PROTEIN positive regulation of mRNA catabolic process#GO:0061014;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;miRNA-mediated post-transcriptional gene silencing#GO:0035195;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of metabolic process#GO:0009892;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000002378.4|UniProtKB=A0A5F8GWQ1 A0A5F8GWQ1 PXK PTHR22999:SF40 PX SERINE/THREONINE KINASE PXK PX DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000001112.5|UniProtKB=F7DPE4 F7DPE4 FHDC1 PTHR45691:SF1 PROTEIN DIAPHANOUS FH2 DOMAIN-CONTAINING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036;cellular component organization#GO:0016043;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000003049.3|UniProtKB=F6PP46 F6PP46 WDPCP PTHR13667:SF5 HOMOLOC-13 WD REPEAT-CONTAINING AND PLANAR CELL POLARITY EFFECTOR PROTEIN FRITZ HOMOLOG MONDO|Ensembl=ENSMODG00000002032.4|UniProtKB=F6QWJ9 F6QWJ9 PTHR45629:SF17 SNF2/RAD54 FAMILY MEMBER DNA REPAIR AND RECOMBINATION PROTEIN RAD54-LIKE catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA translocase activity#GO:0015616;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094 double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;response to stimulus#GO:0050896;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;homologous recombination#GO:0035825;reproductive process#GO:0022414;sexual reproduction#GO:0019953;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA repair#GO:0006281;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 damaged DNA-binding protein#PC00086 MONDO|Ensembl=ENSMODG00000008043.4|UniProtKB=F6Z9I0 F6Z9I0 PTHR46544:SF2 EXTRACELLULAR MATRIX PROTEIN 2-RELATED EXTRACELLULAR MATRIX PROTEIN 2 ISOFORM X1-RELATED protein-containing complex binding#GO:0044877;heparin binding#GO:0008201;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367;collagen binding#GO:0005518;binding#GO:0005488 biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;positive regulation of cell adhesion#GO:0045785;cellular process#GO:0009987;positive regulation of cell-substrate adhesion#GO:0010811;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000012808.4|UniProtKB=F7DYQ6 F7DYQ6 BYSL PTHR12821:SF0 BYSTIN BYSTIN binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000037853.1|UniProtKB=A0A5F8GMF8 A0A5F8GMF8 VN2R501 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000005329.4|UniProtKB=F7D1K9 F7D1K9 PTHR11785:SF303 AMINO ACID TRANSPORTER Y+L AMINO ACID TRANSPORTER 1 L-amino acid transmembrane transporter activity#GO:0015179;basic amino acid transmembrane transporter activity#GO:0015174;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000049324.1|UniProtKB=A0A5F8H9K4 A0A5F8H9K4 PTHR23267:SF313 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 5-2 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000004944.4|UniProtKB=F7ATT8 F7ATT8 DNAAF1 PTHR45973:SF19 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED DYNEIN AXONEMAL ASSEMBLY FACTOR 1 binding#GO:0005488;protein-containing complex binding#GO:0044877 determination of left/right symmetry#GO:0007368;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;pattern specification process#GO:0007389;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;cilium organization#GO:0044782;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;determination of bilateral symmetry#GO:0009855;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;regionalization#GO:0003002;developmental process#GO:0032502;left/right pattern formation#GO:0060972;plasma membrane bounded cell projection assembly#GO:0120031;specification of symmetry#GO:0009799;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000006356.4|UniProtKB=A0A5F8HJH9 A0A5F8HJH9 SCCPDH PTHR12286:SF5 SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE lipid metabolic process#GO:0006629;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509 intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000019121.3|UniProtKB=F7EV62 F7EV62 CCL5 PTHR12015:SF170 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 5 cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 regulation of locomotion#GO:0040012;response to other organism#GO:0051707;biological regulation#GO:0065007;cell migration#GO:0016477;positive regulation of cell migration#GO:0030335;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;positive regulation of locomotion#GO:0040017;regulation of cell migration#GO:0030334;leukocyte migration#GO:0050900;locomotion#GO:0040011;cellular response to chemokine#GO:1990869;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cellular response to stimulus#GO:0051716;cell chemotaxis#GO:0060326;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;regulation of cell motility#GO:2000145;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cytokine-mediated signaling pathway#GO:0019221;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to cytokine#GO:0034097;taxis#GO:0042330;cellular process#GO:0009987;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to stress#GO:0006950;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;cell surface receptor signaling pathway#GO:0007166;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;response to peptide#GO:1901652;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000001736.4|UniProtKB=A0A5F8GDI7 A0A5F8GDI7 SPTBN1 PTHR11915:SF226 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 1 binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular component organization#GO:0016043;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;protein localization to cell periphery#GO:1990778;actin filament-based process#GO:0030029;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000013345.2|UniProtKB=A0A5F8H2Z1 A0A5F8H2Z1 PTHR31958:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 127 COILED-COIL DOMAIN-CONTAINING PROTEIN 127 MONDO|Ensembl=ENSMODG00000014329.4|UniProtKB=F7B9Y8 F7B9Y8 LOC100010481 PTHR11588:SF292 TUBULIN TUBULIN ALPHA-1D CHAIN structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 cell cycle#GO:0007049;cellular component organization#GO:0016043;cell differentiation#GO:0030154;mitotic cell cycle#GO:0000278;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;system development#GO:0048731;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;microtubule-based process#GO:0007017;neurogenesis#GO:0022008 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;tubulin#PC00228 MONDO|Ensembl=ENSMODG00000011835.4|UniProtKB=A0A5F8GM46 A0A5F8GM46 APBA2 PTHR12345:SF12 SYNTENIN RELATED AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 2 peptide binding#GO:0042277;binding#GO:0005488 cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of biological process#GO:0050789 cell junction#GO:0030054;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cytoplasm#GO:0005737;dendritic tree#GO:0097447;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622;dendritic spine#GO:0043197;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;synapse#GO:0045202;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093;Alzheimer disease-amyloid secretase pathway#P00003>X11alpha#P00084 MONDO|Ensembl=ENSMODG00000045072.1|UniProtKB=A0A5F8HFP2 A0A5F8HFP2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000018507.4|UniProtKB=F7AGY1 F7AGY1 COL12A1 PTHR24020:SF17 COLLAGEN ALPHA COLLAGEN ALPHA-1(XII) CHAIN developmental process#GO:0032502;cellular developmental process#GO:0048869;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;endoderm development#GO:0007492;cellular process#GO:0009987;tissue development#GO:0009888;multicellular organismal process#GO:0032501;endoderm formation#GO:0001706;embryo development#GO:0009790;animal gross anatomical part developmental process#GO:0160108;formation of primary germ layer#GO:0001704;anatomical structure development#GO:0048856;gastrulation#GO:0007369;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863 MONDO|Ensembl=ENSMODG00000020895.4|UniProtKB=A0A5F8G681 A0A5F8G681 FGD1 PTHR12673:SF79 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 1 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;filopodium assembly#GO:0046847;cell projection assembly#GO:0030031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000049466.1|UniProtKB=A0A5F8G373 A0A5F8G373 CCNT1 PTHR10026:SF43 CYCLIN CYCLIN-T2 kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209 positive regulation of RNA metabolic process#GO:0051254;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of DNA-templated transcription elongation#GO:0032784;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;organelle lumen#GO:0043233 kinase activator#PC00138;kinase modulator#PC00140 MONDO|Ensembl=ENSMODG00000015990.4|UniProtKB=A0A5F8GPZ5 A0A5F8GPZ5 SCARA5 PTHR19331:SF482 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CLASS A MEMBER 5 cargo receptor activity#GO:0038024 homeostatic process#GO:0042592;endocytosis#GO:0006897;intracellular iron ion homeostasis#GO:0006879;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000047854.1|UniProtKB=A0A5F8H191 A0A5F8H191 LOC100028259 PTHR48002:SF74 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027730.2|UniProtKB=F7B669 F7B669 ZNF75A PTHR23226:SF83 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 75A sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006041.3|UniProtKB=F6ZU50 F6ZU50 ANGPTL1 PTHR19143:SF25 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000011633.3|UniProtKB=F6U0C7 F6U0C7 SLC23A2 PTHR11119:SF33 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SOLUTE CARRIER FAMILY 23 MEMBER 2 sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;sugar transmembrane transporter activity#GO:0051119;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943 cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;carbohydrate transport#GO:0008643;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000046361.1|UniProtKB=A0A5F8GP32 A0A5F8GP32 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000043531.1|UniProtKB=A0A5F8HCD0 A0A5F8HCD0 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000005760.4|UniProtKB=F6XZ22 F6XZ22 AFAP1L1 PTHR14338:SF1 ACTIN FILAMENT-ASSOCIATED PROTEIN 1 FAMILY MEMBER ACTIN FILAMENT-ASSOCIATED PROTEIN 1-LIKE 1 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000036617.1|UniProtKB=K7E1E0 K7E1E0 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000049508.1|UniProtKB=A0A5F8H8P6 A0A5F8H8P6 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000047914.1|UniProtKB=A0A5F8GBX7 A0A5F8GBX7 LOC100010754 PTHR26453:SF156 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027450.2|UniProtKB=K7E3J8 K7E3J8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000040336.1|UniProtKB=A0A5F8H6B0 A0A5F8H6B0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000020659.4|UniProtKB=F7E5W9 F7E5W9 LNX1 PTHR19964:SF14 MULTIPLE PDZ DOMAIN PROTEIN E3 UBIQUITIN-PROTEIN LIGASE LNX ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 Notch signaling pathway#P00045>LNXp80#P01111 MONDO|Ensembl=ENSMODG00000024850.2|UniProtKB=F7EBT4 F7EBT4 KCNA1 PTHR11537:SF24 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 1 potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873 metal ion transport#GO:0030001;action potential#GO:0001508;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810 cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell body#GO:0044297;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;transmembrane transporter complex#GO:1902495;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;main axon#GO:0044304;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000010259.3|UniProtKB=F6W5K4 F6W5K4 TBC1D25 PTHR22957:SF333 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 25 enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of protein-containing complex disassembly#GO:0043244;regulation of autophagy#GO:0010506;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of autophagosome maturation#GO:1901096;regulation of macroautophagy#GO:0016241;regulation of catabolic process#GO:0009894 autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000002697.3|UniProtKB=F7CY44 F7CY44 PTHR15718:SF5 G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH C-TERMINAL DOMAIN-CONTAINING PROTEIN G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH 2 cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;anatomical structure development#GO:0048856;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000021538.3|UniProtKB=F7DZS6 F7DZS6 QPCTL PTHR12283:SF6 GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-LIKE PROTEIN aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;zinc ion binding#GO:0008270;transferase activity#GO:0016740;catalytic activity#GO:0003824;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;acyltransferase activity#GO:0016746;binding#GO:0005488;small molecule binding#GO:0036094 transferase#PC00220 MONDO|Ensembl=ENSMODG00000037084.1|UniProtKB=A0A5F8GJR0 A0A5F8GJR0 PTHR46968:SF2 E3 UBIQUITIN-PROTEIN LIGASE RNF138 E3 UBIQUITIN-PROTEIN LIGASE RNF138 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;nucleic acid binding#GO:0003676;acyltransferase activity#GO:0016746 DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair via single-strand annealing#GO:0045002;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896 membraneless organelle#GO:0043228;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;site of double-strand break#GO:0035861 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000015248.3|UniProtKB=F6UJD0 F6UJD0 PTHR24343:SF181 SERINE/THREONINE KINASE SNF-RELATED SERINE_THREONINE-PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000012677.4|UniProtKB=A0A5F8HGJ3 A0A5F8HGJ3 SLC25A21 PTHR46356:SF1 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000009302.4|UniProtKB=F6YX37 F6YX37 ZPBP PTHR15443:SF5 ZONA PELLUCIDA BINDING PROTEIN SP38 ZONA PELLUCIDA-BINDING PROTEIN 1 cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;single fertilization#GO:0007338;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;cell-cell recognition#GO:0009988;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;cell differentiation#GO:0030154;gamete generation#GO:0007276;fertilization#GO:0009566;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;spermatid differentiation#GO:0048515;acrosome assembly#GO:0001675;male gamete generation#GO:0048232;cellular developmental process#GO:0048869;sperm-egg recognition#GO:0035036;developmental process#GO:0032502;spermatogenesis#GO:0007283;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;binding of sperm to zona pellucida#GO:0007339;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;sexual reproduction#GO:0019953;cell recognition#GO:0008037;spermatid development#GO:0007286 secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982 MONDO|Ensembl=ENSMODG00000020679.4|UniProtKB=F7DKU1 F7DKU1 PPP3CA PTHR45673:SF5 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED PROTEIN PHOSPHATASE 3 CATALYTIC SUBUNIT ALPHA protein binding#GO:0005515;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;calcineurin-NFAT signaling cascade#GO:0033173;calcineurin-mediated signaling#GO:0097720;intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722;cell communication#GO:0007154 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494 protein phosphatase#PC00195 B cell activation#P00010>Calcineurin#P00386;Wnt signaling pathway#P00057>Calcineurin#P01446;T cell activation#P00053>Calcineurin#P01315;Gonadotropin-releasing hormone receptor pathway#P06664>Caln#P06728;CCKR signaling map#P06959>CaN#P07178 MONDO|Ensembl=ENSMODG00000021519.3|UniProtKB=A0A5F8G3J9 A0A5F8G3J9 PTHR24376:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 850 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000000879.3|UniProtKB=F7AUQ4 F7AUQ4 QDPR PTHR15104:SF0 DIHYDROPTERIDINE REDUCTASE DIHYDROPTERIDINE REDUCTASE nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000006206.3|UniProtKB=F6ZSW9 F6ZSW9 PTHR16797:SF4 FACTOR VIII-ASSOCIATED GENE 1 40-KDA HUNTINGTIN-ASSOCIATED PROTEIN transport#GO:0006810;intracellular transport#GO:0046907;organelle localization#GO:0051640;vesicle cytoskeletal trafficking#GO:0099518;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;establishment of vesicle localization#GO:0051650;establishment of organelle localization#GO:0051656;cytoskeleton-dependent intracellular transport#GO:0030705 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000013212.4|UniProtKB=F7EVZ4 F7EVZ4 PTHR19143:SF433 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-2 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000022905.1|UniProtKB=F6Q066 F6Q066 LOC100022370 PTHR26450:SF148 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024059.2|UniProtKB=F7G745 F7G745 KCTD21 PTHR14499:SF57 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD21 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014614.3|UniProtKB=H9H723 H9H723 PTHR23411:SF35 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT MU protein binding#GO:0005515;antigen binding#GO:0003823;binding#GO:0005488;signaling receptor binding#GO:0005102 response to bacterium#GO:0009617;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;defense response#GO:0006952;response to external stimulus#GO:0009605;immune response#GO:0006955;complement activation#GO:0006956;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;adaptive immune response#GO:0002250;biological regulation#GO:0065007;immune system process#GO:0002376;defense response to bacterium#GO:0042742;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;immune effector process#GO:0002252;antibacterial humoral response#GO:0019731;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;defense response to other organism#GO:0098542 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000024487.2|UniProtKB=F7GGR7 F7GGR7 PTHR48002:SF15 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015386.4|UniProtKB=F6TL44 F6TL44 FBXO21 PTHR31350:SF21 SI:DKEY-261L7.2 F-BOX ONLY PROTEIN 21 MONDO|Ensembl=ENSMODG00000051078.1|UniProtKB=A0A5F8GBE6 A0A5F8GBE6 PTHR24390:SF250 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 763 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000003379.4|UniProtKB=F6ZP63 F6ZP63 ZNHIT3 PTHR13483:SF11 BOX C_D SNORNA PROTEIN 1-RELATED ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;cellular component assembly#GO:0022607 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000019535.4|UniProtKB=A0A5F8GNZ7 A0A5F8GNZ7 ANGPT4 PTHR19143:SF31 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-4 receptor tyrosine kinase binding#GO:0030971;protein binding#GO:0005515;protein tyrosine kinase binding#GO:1990782;binding#GO:0005488;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000038687.1|UniProtKB=A0A5F8G3R0 A0A5F8G3R0 PTHR11430:SF117 LIPOCALIN GLYCODELIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000042750.1|UniProtKB=A0A5F8GUA0 A0A5F8GUA0 PTHR45935:SF2 PROTEIN ZBED8-RELATED KRAB DOMAIN-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000017231.4|UniProtKB=F6WHR6 F6WHR6 ENTPD8 PTHR11782:SF31 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 8 hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 organophosphate catabolic process#GO:0046434;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside diphosphate metabolic process#GO:0009132;metabolic process#GO:0008152;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleoside diphosphate catabolic process#GO:0009134;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 hydrolase#PC00121;nucleotide phosphatase#PC00173;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000002548.4|UniProtKB=A0A5F8GKC0 A0A5F8GKC0 CLASP2 PTHR21567:SF30 CLASP CLIP-ASSOCIATING PROTEIN 2 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular localization#GO:0051641;spindle localization#GO:0051653;nuclear division#GO:0000280;mitotic spindle organization#GO:0007052;establishment of organelle localization#GO:0051656;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;chromosome segregation#GO:0007059;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;establishment of mitotic spindle localization#GO:0040001;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;organelle assembly#GO:0070925;organelle localization#GO:0051640;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;spindle organization#GO:0007051;establishment of localization#GO:0051234;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;mitotic sister chromatid segregation#GO:0000070;establishment of spindle localization#GO:0051293;mitotic spindle assembly#GO:0090307 kinetochore#GO:0000776;cell cortex#GO:0005938;basal part of cell#GO:0045178;cytoplasmic microtubule#GO:0005881;chromosome#GO:0005694;mitotic spindle#GO:0072686;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;microtubule#GO:0005874;spindle microtubule#GO:0005876;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule organizing center#GO:0005815;spindle#GO:0005819;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000011189.4|UniProtKB=F6ZAG8 F6ZAG8 ITM2B PTHR10962:SF4 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2B binding#GO:0005488;peptide binding#GO:0042277 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000039525.1|UniProtKB=F6QY46 F6QY46 LOC100013367 PTHR26453:SF0 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13D1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012684.4|UniProtKB=F6VG42 F6VG42 ZBTB41 PTHR24393:SF188 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 41 sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000012407.2|UniProtKB=F6PMP2 F6PMP2 OGFOD2 PTHR24014:SF4 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000007809.4|UniProtKB=F6ZIF4 F6ZIF4 VCP PTHR23077:SF69 AAA-FAMILY ATPASE TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE ATP-dependent activity#GO:0140657;binding#GO:0005488;modification-dependent protein binding#GO:0140030;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;polyubiquitin modification-dependent protein binding#GO:0031593;ribonucleoside triphosphate phosphatase activity#GO:0017111 mitotic spindle organization#GO:0007052;response to stimulus#GO:0050896;cell cycle process#GO:0022402;cellular component organization#GO:0016043;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;organelle disassembly#GO:1903008;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;proteasomal protein catabolic process#GO:0010498;cytoskeleton organization#GO:0007010;response to chemical#GO:0042221;cellular process#GO:0009987;establishment of protein localization#GO:0045184;autophagy#GO:0006914;response to stress#GO:0006950;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;microtubule cytoskeleton organization involved in mitosis#GO:1902850;primary metabolic process#GO:0044238;cell cycle#GO:0007049;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;response to endoplasmic reticulum stress#GO:0034976;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;mitotic cell cycle process#GO:1903047;establishment of localization#GO:0051234;spindle organization#GO:0007051;macromolecule metabolic process#GO:0043170;transport#GO:0006810;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;autophagosome maturation#GO:0097352 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nucleus#GO:0005634;membrane#GO:0016020;cytosol#GO:0005829;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000011233.4|UniProtKB=A0A5F8GU32 A0A5F8GU32 TARDBP PTHR48033:SF9 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN TAR DNA-BINDING PROTEIN 43 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000019832.3|UniProtKB=F6YHK8 F6YHK8 LDLRAD3 PTHR24270:SF24 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 3 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transfer/carrier protein#PC00219;apolipoprotein#PC00052 MONDO|Ensembl=ENSMODG00000037655.1|UniProtKB=A0A5F8GKH8 A0A5F8GKH8 PTHR12234:SF0 FORMIMINOTRANSFERASE-CYCLODEAMINASE FORMIMIDOYLTRANSFERASE-CYCLODEAMINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;lyase activity#GO:0016829 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000024108.2|UniProtKB=F6WJT2 F6WJT2 LRRC3C PTHR24369:SF217 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE RICH REPEAT CONTAINING 3C membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000002320.4|UniProtKB=A0A5F8H6C5 A0A5F8H6C5 SLC27A2 PTHR43107:SF4 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 2 ATP-dependent activity#GO:0140657;carboxylic acid transmembrane transporter activity#GO:0046943;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;monocarboxylic acid transmembrane transporter activity#GO:0008028 steroid metabolic process#GO:0008202;lipid transport#GO:0006869;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;macromolecule localization#GO:0033036;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;fatty acid transport#GO:0015908;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000016211.3|UniProtKB=F7FXX0 F7FXX0 TTPAL PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000045979.1|UniProtKB=F6U0H8 F6U0H8 OR52N2 PTHR26450:SF161 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52N2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008437.4|UniProtKB=F7AKE3 F7AKE3 MYZAP PTHR23171:SF2 GDOWN1 MYOCARDIAL ZONULA ADHERENS PROTEIN cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;myofibril#GO:0030016;supramolecular fiber#GO:0099512;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;contractile muscle fiber#GO:0043292;sarcomere#GO:0030017;nuclear protein-containing complex#GO:0140513;RNA polymerase II, core complex#GO:0005665;intracellular membrane-bounded organelle#GO:0043231;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;I band#GO:0031674;transferase complex#GO:1990234 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000020181.3|UniProtKB=A0A5F8H952 A0A5F8H952 PTHR14389:SF15 SI:CH1073-475A24.1 SERINE PROTEASE FAM111A-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000001213.4|UniProtKB=A0A5F8GFV7 A0A5F8GFV7 KCNQ3 PTHR11537:SF5 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 3 potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215 establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;action potential#GO:0001508 protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;main axon#GO:0044304;neuron projection#GO:0043005;transporter complex#GO:1990351;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;axon#GO:0030424 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000040774.1|UniProtKB=K7E4X9 K7E4X9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000015625.3|UniProtKB=A0A5F8HHN4 A0A5F8HHN4 FZD10 PTHR11309:SF86 FRIZZLED FRIZZLED-10 signaling receptor activity#GO:0038023;protein binding#GO:0005515;molecular transducer activity#GO:0060089;Wnt-protein binding#GO:0017147;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 non-canonical Wnt signaling pathway#GO:0035567;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475 MONDO|Ensembl=ENSMODG00000007447.4|UniProtKB=F7BU56 F7BU56 PTHR21223:SF4 CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN 1 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cilium#GO:0005929;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000002820.5|UniProtKB=F7EJ55 F7EJ55 ZNF862 PTHR46880:SF3 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 862 MONDO|Ensembl=ENSMODG00000003725.5|UniProtKB=F7GAC1 F7GAC1 MAML1 PTHR15692:SF19 MASTERMIND-LIKE MASTERMIND-LIKE PROTEIN 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;Notch signaling pathway#GO:0007219;regulation of biosynthetic process#GO:0009889;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;positive regulation of transcription by RNA polymerase II#GO:0045944 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 Notch signaling pathway#P00045>Mastermind#P01106 MONDO|Ensembl=ENSMODG00000000492.3|UniProtKB=A0A5F8GNF3 A0A5F8GNF3 SHISA4 PTHR31395:SF5 SHISA PROTEIN SHISA-4 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000957.4|UniProtKB=F7F7H0 F7F7H0 SLC36A4 PTHR22950:SF190 AMINO ACID TRANSPORTER NEUTRAL AMINO ACID UNIPORTER 4 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175 transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;alanine transport#GO:0032328;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807 membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774 secondary carrier transporter#PC00258;amino acid transporter#PC00046 MONDO|Ensembl=ENSMODG00000024869.1|UniProtKB=F6YV78 F6YV78 SMCO3 PTHR35972:SF1 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 3 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 3 MONDO|Ensembl=ENSMODG00000011785.4|UniProtKB=F6QNJ2 F6QNJ2 CSTF2 PTHR45735:SF2 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000011254.3|UniProtKB=F6R1Y5 F6R1Y5 PTHR15160:SF17 VON HIPPEL-LINDAU PROTEIN VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;transcription regulator activity#GO:0140110;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Hypoxia response via HIF activation#P00030>VHL#P00816 MONDO|Ensembl=ENSMODG00000008292.3|UniProtKB=F6YIF1 F6YIF1 SAP18 PTHR13082:SF0 SAP18 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 Hedgehog signaling pathway#P00025>Sap18#P00697 MONDO|Ensembl=ENSMODG00000012557.4|UniProtKB=F6PLN8 F6PLN8 NPEPPS PTHR11533:SF174 PROTEASE M1 ZINC METALLOPROTEASE PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238 proteolysis#GO:0006508;metabolic process#GO:0008152;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000038535.1|UniProtKB=F7D5C4 F7D5C4 LOC100026078 PTHR26452:SF253 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10Q1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002076.4|UniProtKB=F6UZL6 F6UZL6 PTHR13544:SF0 SELENOPROTEIN T THIOREDOXIN REDUCTASE-LIKE SELENOPROTEIN T antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 cellular homeostasis#GO:0019725;homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000012853.4|UniProtKB=F7C9P3 F7C9P3 KIF14 PTHR24115:SF546 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF14 microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774 central nervous system development#GO:0007417;forebrain development#GO:0030900;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;localization#GO:0051179;anatomical structure development#GO:0048856;cellular localization#GO:0051641;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;brain development#GO:0007420;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of vesicle localization#GO:0051650;nervous system development#GO:0007399;organelle transport along microtubule#GO:0072384;head development#GO:0060322;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;multicellular organism development#GO:0007275;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;animal organ development#GO:0048513;vesicle cytoskeletal trafficking#GO:0099518;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;developmental process#GO:0032502;transport#GO:0006810 cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000024817.2|UniProtKB=F7AY05 F7AY05 PTHR12387:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;proteasome regulatory particle, lid subcomplex#GO:0008541;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;nucleus#GO:0005634 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000018095.4|UniProtKB=F7FG39 F7FG39 ABHD10 PTHR16138:SF7 MYCOPHENOLIC ACID ACYL-GLUCURONIDE ESTERASE, MITOCHONDRIAL PALMITOYL-PROTEIN THIOESTERASE ABHD10, MITOCHONDRIAL hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on glycosyl bonds#GO:0016798;thiolester hydrolase activity#GO:0016790;palmitoyl hydrolase activity#GO:0098599;hydrolase activity#GO:0016787 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 esterase#PC00097;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000006608.3|UniProtKB=F6ZWX0 F6ZWX0 C2CD4C PTHR46291:SF5 C2 DOMAIN-CONTAINING PROTEIN C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4C MONDO|Ensembl=ENSMODG00000022954.2|UniProtKB=F6S233 F6S233 PTHR10388:SF69 EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 SUI1 DOMAIN-CONTAINING PROTEIN translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribonucleoprotein complex#GO:1990904 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000006106.5|UniProtKB=A0A5F8G9P1 A0A5F8G9P1 SHANK3 PTHR24135:SF4 SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 3 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor complex adaptor activity#GO:0030159 multicellular organismal process#GO:0032501;cell junction organization#GO:0034330;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;system process#GO:0003008;cognition#GO:0050890;synapse organization#GO:0050808;nervous system process#GO:0050877 neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cell junction#GO:0030054;synaptic membrane#GO:0097060;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;cell projection#GO:0042995;postsynapse#GO:0098794;dendritic spine#GO:0043197;postsynaptic membrane#GO:0045211;dendrite#GO:0030425;postsynaptic density#GO:0014069;dendritic tree#GO:0097447 scaffold/adaptor protein#PC00226 Ionotropic glutamate receptor pathway#P00037>PSD95#P00999 MONDO|Ensembl=ENSMODG00000010406.4|UniProtKB=A0A5F8GIU7 A0A5F8GIU7 PTHR14239:SF3 DUDULIN-RELATED STEAP FAMILY MEMBER 1B-RELATED ferric-chelate reductase activity#GO:0000293;catalytic activity#GO:0003824;oxidoreductase activity, acting on metal ions#GO:0016722;oxidoreductase activity#GO:0016491 monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;transport#GO:0006810 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982 reductase#PC00198 MONDO|Ensembl=ENSMODG00000001011.3|UniProtKB=F6ZFJ6 F6ZFJ6 MCFD2 PTHR23104:SF14 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane#GO:0016020;membrane protein complex#GO:0098796 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000003808.3|UniProtKB=F6ZJ64 F6ZJ64 DCUN1D2 PTHR12281:SF16 RP42 RELATED DCN1-LIKE PROTEIN 2 protein binding#GO:0005515;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;regulation of protein modification process#GO:0031399;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000021578.1|UniProtKB=Q65CI8 Q65CI8 ATP6 PTHR11410:SF0 ATP SYNTHASE SUBUNIT A ATP SYNTHASE F(0) COMPLEX SUBUNIT A transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;proton channel activity#GO:0015252;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324 nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;organophosphate biosynthetic process#GO:0090407;ribose phosphate biosynthetic process#GO:0046390;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165 respiratory chain complex#GO:0098803;membrane#GO:0016020;membrane protein complex#GO:0098796;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proton-transporting ATP synthase complex#GO:0045259;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 primary active transporter#PC00068;ATP synthase#PC00002 ATP synthesis#P02721>ATP synthetase F0#P02797 MONDO|Ensembl=ENSMODG00000001755.4|UniProtKB=F6WZK4 F6WZK4 ALX3 PTHR24329:SF578 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN ARISTALESS-LIKE 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000044369.1|UniProtKB=A0A5F8HF48 A0A5F8HF48 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000051355.1|UniProtKB=A0A5F8GJ30 A0A5F8GJ30 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009490.4|UniProtKB=F6QKL7 F6QKL7 TCN2 PTHR10559:SF14 TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR TRANSCOBALAMIN-2 binding#GO:0005488;small molecule binding#GO:0036094;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363 establishment of localization#GO:0051234;vitamin transport#GO:0051180;localization#GO:0051179;nitrogen compound transport#GO:0071705;transport#GO:0006810 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000010679.4|UniProtKB=A0A5F8GV49 A0A5F8GV49 FAM76A PTHR46176:SF2 LD21662P PROTEIN FAM76A membraneless organelle#GO:0043228;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear speck#GO:0016607;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000000462.3|UniProtKB=F6URP7 F6URP7 MAGOHB PTHR12638:SF2 PROTEIN MAGO NASHI HOMOLOG PROTEIN MAGO NASHI HOMOLOG regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;nuclear mRNA surveillance#GO:0071028;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;exon-exon junction complex#GO:0035145;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 MONDO|Ensembl=ENSMODG00000011895.3|UniProtKB=F7EH88 F7EH88 PAIP2 PTHR13154:SF2 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2 translation regulator activity#GO:0045182 negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of translation#GO:0017148;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000012496.4|UniProtKB=F6Q2U3 F6Q2U3 PTHR26453:SF627 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001368.5|UniProtKB=F7FVV4 F7FVV4 SP4 PTHR23235:SF17 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000048366.1|UniProtKB=A0A5F8H0W8 A0A5F8H0W8 YKT6 PTHR45806:SF1 SYNAPTOBREVIN HOMOLOG YKT6 SYNAPTOBREVIN HOMOLOG YKT6 SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;metabolic process#GO:0008152;transport#GO:0006810;Golgi vesicle transport#GO:0048193;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;vacuole fusion, non-autophagic#GO:0042144;organelle membrane fusion#GO:0090174;macroautophagy#GO:0016236;membrane fusion#GO:0061025;organelle organization#GO:0006996;autophagy#GO:0006914;cellular process#GO:0009987;localization#GO:0051179;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;vacuole fusion#GO:0097576;catabolic process#GO:0009056;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;intra-Golgi vesicle-mediated transport#GO:0006891 vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;intracellular organelle#GO:0043229;autophagosome#GO:0005776 MONDO|Ensembl=ENSMODG00000014360.3|UniProtKB=F6U4P5 F6U4P5 POF1B PTHR22546:SF0 PREMATURE OVARIAN FAILURE, 1B PROTEIN POF1B protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cellular component assembly#GO:0022607;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;actin filament organization#GO:0007015;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cell development#GO:0048468;actin cytoskeleton organization#GO:0030036;cell junction organization#GO:0034330;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell-cell junction#GO:0005911;intracellular membraneless organelle#GO:0043232;bicellular tight junction#GO:0005923;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;actin filament#GO:0005884;apical junction complex#GO:0043296;cytoskeleton#GO:0005856;adherens junction#GO:0005912;cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;tight junction#GO:0070160 MONDO|Ensembl=ENSMODG00000024057.2|UniProtKB=F7GGM7 F7GGM7 THRSP PTHR14315:SF18 SPOT14 FAMILY MEMBER THYROID HORMONE-INDUCIBLE HEPATIC PROTEIN molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 regulation of lipid metabolic process#GO:0019216;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of lipid biosynthetic process#GO:0046890;regulation of cellular process#GO:0050794 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000005364.4|UniProtKB=A0A5F8H9W1 A0A5F8H9W1 IGSF9B PTHR10075:SF114 BASIGIN RELATED PROTEIN TURTLE HOMOLOG B cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000019447.4|UniProtKB=F6RXI9 F6RXI9 DNMT3B PTHR23068:SF9 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED DNA (CYTOSINE-5)-METHYLTRANSFERASE 3B methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097 negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA methyltransferase#PC00013 MONDO|Ensembl=ENSMODG00000038159.1|UniProtKB=A0A5F8G1V7 A0A5F8G1V7 PTHR14002:SF9 ENDOGLIN/TGF-BETA RECEPTOR TYPE III TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE 3-LIKE PROTEIN transferase activity#GO:0016740;carbohydrate derivative binding#GO:0097367;kinase activity#GO:0016301;transforming growth factor beta receptor activity#GO:0005024;signaling receptor activity#GO:0038023;cytokine receptor binding#GO:0005126;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transforming growth factor beta binding#GO:0050431;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;cytokine binding#GO:0019955;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor binding#GO:0005102;glycosaminoglycan binding#GO:0005539;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;response to transforming growth factor beta#GO:0071559;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;tissue development#GO:0009888;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;mesenchyme development#GO:0060485;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor signaling pathway#GO:0007179;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;mesenchymal cell differentiation#GO:0048762;cell surface receptor signaling pathway#GO:0007166;animal organ development#GO:0048513 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028532.2|UniProtKB=K7E1F0 K7E1F0 TMEM154 PTHR36526:SF1 TRANSMEMBRANE PROTEIN 154 TRANSMEMBRANE PROTEIN 154 MONDO|Ensembl=ENSMODG00000003521.4|UniProtKB=A0A5F8GIY5 A0A5F8GIY5 CDC14A PTHR23339:SF77 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE CDC14A phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of mitotic cell cycle phase transition#GO:1901990;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;organelle assembly#GO:0070925;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;cellular component assembly#GO:0022607;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;positive regulation of cell cycle#GO:0045787;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;cell projection assembly#GO:0030031;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031 intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815 protein phosphatase#PC00195;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000006429.3|UniProtKB=F7EZH4 F7EZH4 ALDH6A1 PTHR43866:SF3 MALONATE-SEMIALDEHYDE DEHYDROGENASE METHYLMALONATE-SEMIALDEHYDE_MALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;pyrimidine nucleobase metabolic process#GO:0006206;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;carboxylic acid catabolic process#GO:0046395;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;oxoacid metabolic process#GO:0043436;primary metabolic process#GO:0044238;pyrimidine nucleobase catabolic process#GO:0006208;carboxylic acid metabolic process#GO:0019752;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleobase catabolic process#GO:0046113;small molecule catabolic process#GO:0044282 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 Pyrimidine Metabolism#P02771>Methylmalonate Semialdehyde Dehydrogenase#P03124 MONDO|Ensembl=ENSMODG00000024512.2|UniProtKB=F7AKT5 F7AKT5 PTHR48002:SF109 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K15 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007821.4|UniProtKB=A0A5F8GHF2 A0A5F8GHF2 ARHGAP12 PTHR23176:SF107 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 12 GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 MONDO|Ensembl=ENSMODG00000002034.3|UniProtKB=F6QW93 F6QW93 PSMA5 PTHR11599:SF14 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-5 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 nucleus#GO:0005634;proteasome complex#GO:0000502;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 MONDO|Ensembl=ENSMODG00000011550.4|UniProtKB=F6QWE0 F6QWE0 MSTN PTHR11848:SF150 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 8 cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;muscle tissue development#GO:0060537;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;response to transforming growth factor beta#GO:0071559;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;animal organ development#GO:0048513;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;muscle organ development#GO:0007517;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;tissue development#GO:0009888;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;skeletal muscle tissue development#GO:0007519;signal transduction#GO:0007165 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000000291.4|UniProtKB=F6WAT0 F6WAT0 SYNPO2L PTHR24217:SF10 PUTATIVE-RELATED SYNAPTOPODIN 2-LIKE PROTEIN protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488 regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;cellular developmental process#GO:0048869;positive regulation of actin filament bundle assembly#GO:0032233;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;regulation of supramolecular fiber organization#GO:1902903;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;regulation of cell communication#GO:0010646;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular anatomical entity morphogenesis#GO:0032989;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;regulation of small GTPase mediated signal transduction#GO:0051056;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of Rho protein signal transduction#GO:0035023;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;actomyosin structure organization#GO:0031032;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;striated muscle cell development#GO:0055002 sarcomere#GO:0030017;membraneless organelle#GO:0043228;I band#GO:0031674;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000000640.4|UniProtKB=F6SUT3 F6SUT3 PTHR31393:SF2 C5ORF31 SPERM-ASSOCIATED MICROTUBULE INNER PROTEIN 4 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000040486.1|UniProtKB=A0A5F8GMZ0 A0A5F8GMZ0 PNMT PTHR10867:SF18 NNMT/PNMT/TEMT FAMILY MEMBER PHENYLETHANOLAMINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 MONDO|Ensembl=ENSMODG00000020818.4|UniProtKB=F6RSL4 F6RSL4 PTHR12035:SF125 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 5 anion binding#GO:0043168;carboxylic acid binding#GO:0031406;binding#GO:0005488;small molecule binding#GO:0036094;carbohydrate derivative binding#GO:0097367;ion binding#GO:0043167;organic acid binding#GO:0043177 cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000003595.3|UniProtKB=F7FBH6 F7FBH6 ACAA2 PTHR18919:SF175 ACETYL-COA C-ACYLTRANSFERASE 3-KETOACYL-COA THIOLASE, MITOCHONDRIAL acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;lipid modification#GO:0030258;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000009335.4|UniProtKB=F7GAY7 F7GAY7 POLR1A PTHR19376:SF11 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1 nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription by RNA polymerase I#GO:0006360;rRNA transcription#GO:0009303;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase I complex#GO:0005736;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000023683.1|UniProtKB=F6T0L6 F6T0L6 DRD1 PTHR24248:SF139 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(1A) DOPAMINE RECEPTOR neurotransmitter receptor activity#GO:0030594;postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;biological regulation#GO:0065007;G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D1/D5#P05948;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 MONDO|Ensembl=ENSMODG00000018981.5|UniProtKB=F7FP88 F7FP88 SRF PTHR48019:SF168 SERUM RESPONSE FACTOR HOMOLOG SERUM RESPONSE FACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;MADS box transcription factor#PC00250 PDGF signaling pathway#P00047>SRF#P01165;CCKR signaling map#P06959>SRF#P07181;PDGF signaling pathway#P00047>c-fos#P01145;Interleukin signaling pathway#P00036>SRF#P00987;Ras Pathway#P04393>SRF#P04561;p38 MAPK pathway#P05918>SRF#P06025;Gonadotropin-releasing hormone receptor pathway#P06664>SRF#P06811 MONDO|Ensembl=ENSMODG00000023255.3|UniProtKB=F6X8J8 F6X8J8 PTHR22677:SF3 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 60 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 60 MONDO|Ensembl=ENSMODG00000002011.2|UniProtKB=F6QXP9 F6QXP9 RPS17 PTHR10732:SF14 40S RIBOSOMAL PROTEIN S17 SMALL RIBOSOMAL SUBUNIT PROTEIN ES17 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000003430.5|UniProtKB=F7GCC2 F7GCC2 DMRT2 PTHR12322:SF122 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;sex differentiation#GO:0007548;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000023712.3|UniProtKB=F7C9L7 F7C9L7 LOC100027389 PTHR47966:SF66 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSINOGEN C catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;aspartic protease#PC00053 MONDO|Ensembl=ENSMODG00000001402.4|UniProtKB=F7F5A4 F7F5A4 PTHR12709:SF5 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription by RNA polymerase I#GO:0006360;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase I complex#GO:0005736;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000050465.1|UniProtKB=A0A5F8HE53 A0A5F8HE53 MEOX2 PTHR24328:SF1 HOMEOBOX PROTEIN MOX HOMEOBOX PROTEIN MOX-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000012518.4|UniProtKB=A0A5F8H9D2 A0A5F8H9D2 OSBPL7 PTHR10972:SF85 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 7 small molecule binding#GO:0036094;binding#GO:0005488;sterol binding#GO:0032934;alcohol binding#GO:0043178;lipid binding#GO:0008289;cholesterol binding#GO:0015485;steroid binding#GO:0005496 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle envelope#GO:0031967;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;perinuclear region of cytoplasm#GO:0048471;nuclear envelope#GO:0005635;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;nucleus#GO:0005634;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000025701.3|UniProtKB=F6TIX3 F6TIX3 PTHR24300:SF177 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2J2 binding#GO:0005488;tetrapyrrole binding#GO:0046906;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000005928.2|UniProtKB=F6WX38 F6WX38 PLA2G12A PTHR12824:SF7 GROUP XII SECRETORY PHOSPHOLIPASE A2 FAMILY MEMBER GROUP XIIA SECRETORY PHOSPHOLIPASE A2 hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;A2-type glycerophospholipase activity#GO:0004623;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity#GO:0016787 hydrolase#PC00121;phospholipase#PC00186;lipase#PC00143 MONDO|Ensembl=ENSMODG00000011425.4|UniProtKB=F6RKH2 F6RKH2 PTHR47025:SF30 AUTOIMMUNE REGULATOR AUTOIMMUNE REGULATOR DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;histone binding#GO:0042393 lymphocyte activation#GO:0046649;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;multicellular organism development#GO:0007275;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cell development#GO:0048468;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;lymphocyte mediated immunity#GO:0002449;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of biosynthetic process#GO:0009889;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;T cell differentiation#GO:0030217;animal organ development#GO:0048513;morphogenesis of an epithelium#GO:0002009;humoral immune response#GO:0006959;positive regulation of transcription by RNA polymerase II#GO:0045944;immune effector process#GO:0002252;cell differentiation#GO:0030154;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;mononuclear cell differentiation#GO:1903131;leukocyte mediated immunity#GO:0002443;immune system development#GO:0002520;positive regulation of metabolic process#GO:0009893;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;tissue development#GO:0009888;adaptive immune response#GO:0002250;hemopoiesis#GO:0030097;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of leukocyte migration#GO:0002685;leukocyte activation#GO:0045321;regulation of DNA-templated transcription#GO:0006355;tissue morphogenesis#GO:0048729;regulation of cell motility#GO:2000145;positive regulation of biosynthetic process#GO:0009891;system development#GO:0048731;regulation of lymphocyte migration#GO:2000401;cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;T cell mediated immunity#GO:0002456 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000018165.3|UniProtKB=F7CCZ2 F7CCZ2 PTHR11129:SF3 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT PROTEIN PRENYLTRANSFERASE ALPHA SUBUNIT REPEAT-CONTAINING PROTEIN 1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity#GO:0003824;transferase activity#GO:0016740 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000025690.3|UniProtKB=F7F0N8 F7F0N8 UNC93A PTHR19444:SF13 UNC-93 RELATED N-ACETYLGLUCOSAMINE TRANSPORTER UNC93A transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000004361.4|UniProtKB=A0A5F8GSW0 A0A5F8GSW0 RABGAP1L PTHR47219:SF7 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE RAB GTPASE-ACTIVATING PROTEIN 1-LIKE GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;enzyme binding#GO:0019899 regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880 G-protein modulator#PC00022;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000046174.1|UniProtKB=A0A5F8H5V9 A0A5F8H5V9 TGM7 PTHR11590:SF41 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE Z transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 transferase#PC00220 MONDO|Ensembl=ENSMODG00000002221.4|UniProtKB=F7DG03 F7DG03 CLCC1 PTHR34093:SF1 CHLORIDE CHANNEL CLIC-LIKE PROTEIN 1 CHLORIDE CHANNEL CLIC-LIKE PROTEIN 1 chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000014476.3|UniProtKB=F7A5B1 F7A5B1 PTHR10880:SF48 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;chromatin#GO:0000785;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000014844.4|UniProtKB=F6UU82 F6UU82 DGKH PTHR11255:SF37 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE ETA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;neutral lipid metabolic process#GO:0006638 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;kinase#PC00137 MONDO|Ensembl=ENSMODG00000015497.4|UniProtKB=F6WEQ0 F6WEQ0 PNKD PTHR11935:SF116 BETA LACTAMASE DOMAIN THIOESTERASE PNKD-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;hydrolase activity#GO:0016787 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000008235.4|UniProtKB=F6ZXU8 F6ZXU8 HTRA1 PTHR22939:SF13 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA1 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 positive regulation of apoptotic process#GO:0043065;macromolecule metabolic process#GO:0043170;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;protein metabolic process#GO:0019538;proteolysis#GO:0006508;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cell death#GO:0008219;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000021278.4|UniProtKB=F6T2D4 F6T2D4 MED12L PTHR46007:SF3 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12-LIKE PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254 nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000010616.2|UniProtKB=F7G807 F7G807 LOC100009856 PTHR11028:SF3 VACUOLAR ATP SYNTHASE SUBUNIT AC39 V-TYPE PROTON ATPASE SUBUNIT D 1 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626 monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;biological regulation#GO:0065007;intracellular transport#GO:0046907;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;cellular localization#GO:0051641;localization#GO:0051179;regulation of biological quality#GO:0065008 vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;proton-transporting two-sector ATPase complex#GO:0016469;transporter complex#GO:1990351;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;ATPase complex#GO:1904949;endosome#GO:0005768;intracellular organelle#GO:0043229;ATPase dependent transmembrane transport complex#GO:0098533;early endosome#GO:0005769;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000042625.1|UniProtKB=A0A5F8GDN9 A0A5F8GDN9 PTHR11873:SF1 RETINOL-BINDING PROTEIN 4 PURPURIN transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000019480.3|UniProtKB=F6WAE4 F6WAE4 PDRG1 PTHR21162:SF0 P53 AND DNA DAMAGE-REGULATED PROTEIN P53 AND DNA DAMAGE-REGULATED PROTEIN 1 MONDO|Ensembl=ENSMODG00000002771.2|UniProtKB=F6YGQ2 F6YGQ2 TMED6 PTHR22811:SF45 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 6 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 Golgi organization#GO:0007030;cellular component organization#GO:0016043;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;intracellular organelle#GO:0043229 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000007601.4|UniProtKB=F6T654 F6T654 INCENP PTHR13142:SF1 INNER CENTROMERE PROTEIN INNER CENTROMERE PROTEIN intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;midbody#GO:0030496;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;membraneless organelle#GO:0043228;spindle#GO:0005819;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775 MONDO|Ensembl=ENSMODG00000020709.4|UniProtKB=F7BAX6 F7BAX6 C6H4orf17 PTHR33772:SF2 THYMUS, BRAIN AND TESTES-ASSOCIATED RIKEN CDNA 4930579F01 GENE MONDO|Ensembl=ENSMODG00000019143.4|UniProtKB=A0A5F8H1P7 A0A5F8H1P7 RFFL PTHR14879:SF2 CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RIFIFYLIN ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;regulation of extrinsic apoptotic signaling pathway#GO:2001236;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of response to stimulus#GO:0048583;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;negative regulation of signal transduction#GO:0009968;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000008332.2|UniProtKB=F7F2Z5 F7F2Z5 CIAO1 PTHR19920:SF0 WD40 PROTEIN CIAO1 CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000017282.4|UniProtKB=F6SMW6 F6SMW6 NMBR PTHR45695:SF8 LEUCOKININ RECEPTOR-RELATED NEUROMEDIN-B RECEPTOR G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004394.4|UniProtKB=F6SVP6 F6SVP6 SPON2 PTHR11311:SF15 SPONDIN SPONDIN-2 cellular process#GO:0009987;cell adhesion#GO:0007155 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000023512.2|UniProtKB=F7DE78 F7DE78 LOC100618339 PTHR24377:SF878 IP01015P-RELATED ZINC FINGER PROTEIN 670 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019439.4|UniProtKB=F6QG57 F6QG57 ISL1 PTHR24204:SF4 INSULIN GENE ENHANCER PROTEIN INSULIN GENE ENHANCER PROTEIN ISL-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;positive regulation of transcription by RNA polymerase II#GO:0045944;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell fate specification#GO:0001708;neuron differentiation#GO:0030182;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;axonogenesis#GO:0007409;neuron development#GO:0048666;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of transcription by RNA polymerase II#GO:0006357;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;plasma membrane bounded cell projection organization#GO:0120036;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;neuron fate commitment#GO:0048663;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#G06682;Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#P06791;Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#G06896 MONDO|Ensembl=ENSMODG00000001807.4|UniProtKB=A0A5F8G9Y0 A0A5F8G9Y0 GRIA2 PTHR18966:SF99 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 2 gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;channel activity#GO:0015267;molecular transducer activity#GO:0060089;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066 chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;postsynapse#GO:0098794;dendritic spine#GO:0043197;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;neuron spine#GO:0044309;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;neuron projection#GO:0043005;protein-containing complex#GO:0032991;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu2#P01017;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 MONDO|Ensembl=ENSMODG00000021079.4|UniProtKB=F6V159 F6V159 LOC100027246 PTHR43215:SF18 RADIAL SPOKE HEAD 1 HOMOLOG RADIAL SPOKE HEAD 1 HOMOLOG cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;cellular developmental process#GO:0048869;developmental process#GO:0032502;spermatogenesis#GO:0007283;plasma membrane bounded cell projection assembly#GO:0120031;reproductive process#GO:0022414;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;organelle assembly#GO:0070925 intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000021555.4|UniProtKB=A0A5F8GNH2 A0A5F8GNH2 FKBP9 PTHR46046:SF2 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP9 MONDO|Ensembl=ENSMODG00000048991.1|UniProtKB=A0A5F8GEV2 A0A5F8GEV2 TAGLN2 PTHR47385:SF20 CALPONIN TRANSGELIN-2 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000008563.4|UniProtKB=F7CXI3 F7CXI3 PTHR23120:SF14 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 2A cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000020058.2|UniProtKB=F6YT52 F6YT52 PTHR48018:SF193 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P53-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016687.4|UniProtKB=F7DLX6 F7DLX6 ITIH5 PTHR10338:SF62 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H5 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000015590.4|UniProtKB=F6ZUH7 F6ZUH7 SUPT7L PTHR28598:SF1 STAGA COMPLEX 65 SUBUNIT GAMMA STAGA COMPLEX 65 SUBUNIT GAMMA transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 MONDO|Ensembl=ENSMODG00000024958.2|UniProtKB=F6UCD6 F6UCD6 TCF24 PTHR23349:SF48 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 24 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000039753.1|UniProtKB=A0A5F8HIM5 A0A5F8HIM5 PTHR34141:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000014580.3|UniProtKB=F7DS58 F7DS58 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000003001.4|UniProtKB=F6Q3T2 F6Q3T2 FOXN3 PTHR13962:SF20 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000036993.1|UniProtKB=A0A5F8H5P0 A0A5F8H5P0 LRRC57 PTHR45752:SF212 LEUCINE-RICH REPEAT-CONTAINING CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000025522.3|UniProtKB=F6VIZ4 F6VIZ4 PTHR21580:SF64 SHIPPO-1-RELATED SPERM-TAIL PG-RICH REPEAT-CONTAINING PROTEIN 2 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000043497.1|UniProtKB=A0A5F8G9X8 A0A5F8G9X8 PTHR13596:SF2 SMALL EDRK-RICH FACTOR 1 SMALL EDRK-RICH FACTOR 2 MONDO|Ensembl=ENSMODG00000001103.3|UniProtKB=F7DPL2 F7DPL2 PTHR11671:SF5 V-TYPE ATP SYNTHASE SUBUNIT D V-TYPE PROTON ATPASE SUBUNIT D ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;biological regulation#GO:0065007;homeostatic process#GO:0042592;regulation of pH#GO:0006885;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;regulation of intracellular pH#GO:0051453;vacuolar acidification#GO:0007035;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;intracellular chemical homeostasis#GO:0055082 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting two-sector ATPase complex#GO:0016469 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000025077.2|UniProtKB=F6RQ48 F6RQ48 LOC100016223 PTHR11593:SF10 60S RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN UL22 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000017624.4|UniProtKB=F6ZT41 F6ZT41 ZMPSTE24 PTHR10120:SF24 CAAX PRENYL PROTEASE 1 CAAX PRENYL PROTEASE 1 HOMOLOG catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000020393.4|UniProtKB=F7C039 F7C039 PTPRR PTHR46198:SF2 PROTEIN-TYROSINE-PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE R catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000021212.4|UniProtKB=A0A5F8GLY2 A0A5F8GLY2 MFF PTHR16501:SF17 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 11 MITOCHONDRIAL FISSION FACTOR macromolecule localization#GO:0033036;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;positive regulation of developmental process#GO:0051094;regulation of anatomical structure morphogenesis#GO:0022603;intracellular protein localization#GO:0008104;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;regulation of organelle organization#GO:0033043;protein localization to mitochondrion#GO:0070585;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of developmental process#GO:0050793;positive regulation of mitochondrial fission#GO:0090141;regulation of mitochondrial fission#GO:0090140;positive regulation of cellular component organization#GO:0051130;localization#GO:0051179;positive regulation of organelle organization#GO:0010638 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;microbody#GO:0042579;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000011452.4|UniProtKB=F6W186 F6W186 PTHR23192:SF32 OLFACTOMEDIN-RELATED OLFACTOMEDIN 5 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000045812.1|UniProtKB=A0A5F8GY69 A0A5F8GY69 PTHR16520:SF3 KINETOCHORE SCAFFOLD 1 OUTER KINETOCHORE KNL1 COMPLEX SUBUNIT KNL1 cell cycle process#GO:0022402;cellular process#GO:0009987;attachment of spindle microtubules to kinetochore#GO:0008608;nuclear chromosome segregation#GO:0098813;protein localization to kinetochore#GO:0034501;cell cycle#GO:0007049;macromolecule localization#GO:0033036;chromosome localization#GO:0050000;protein localization to organelle#GO:0033365;chromosome segregation#GO:0007059;organelle localization#GO:0051640;metaphase chromosome alignment#GO:0051310;intracellular protein localization#GO:0008104;localization#GO:0051179 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000011241.3|UniProtKB=F6RMU5 F6RMU5 PTHR10972:SF205 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN 1 lipid binding#GO:0008289;steroid binding#GO:0005496;sterol binding#GO:0032934;binding#GO:0005488 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000013889.3|UniProtKB=A0A5F8G646 A0A5F8G646 MRPS24 PTHR21244:SF1 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S24 SMALL RIBOSOMAL SUBUNIT PROTEIN US3M ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000049982.1|UniProtKB=A0A5F8G225 A0A5F8G225 PTHR45598:SF5 PROTEIN CBG11839-RELATED 4FE-4S FERREDOXIN-TYPE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000040132.1|UniProtKB=A0A5F8H135 A0A5F8H135 CBR4 PTHR42760:SF133 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000002226.3|UniProtKB=F7DFX7 F7DFX7 PTHR24347:SF427 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE DCLK3 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000048682.1|UniProtKB=A0A5F8HEF3 A0A5F8HEF3 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000042487.1|UniProtKB=A0A5F8HHW2 A0A5F8HHW2 PTHR11442:SF48 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT ALPHA heme binding#GO:0020037;molecular carrier activity#GO:0140104;binding#GO:0005488;tetrapyrrole binding#GO:0046906 cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;homeostatic process#GO:0042592;cell development#GO:0048468;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;localization#GO:0051179;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;cellular process#GO:0009987;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;developmental process#GO:0032502;transport#GO:0006810;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;multicellular organismal-level homeostasis#GO:0048871 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219;globin#PC00107 MONDO|Ensembl=ENSMODG00000017308.4|UniProtKB=A0A5F8GWL5 A0A5F8GWL5 PTHR15431:SF14 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN CENTRIOLE AND CENTRIOLAR SATELLITE PROTEIN OFD1 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514 MONDO|Ensembl=ENSMODG00000010505.3|UniProtKB=F7E9U1 F7E9U1 FZD1 PTHR11309:SF81 FRIZZLED FRIZZLED-1 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089 cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Angiogenesis#P00005>Fzd#P00189;Cadherin signaling pathway#P00012>Frizzled#P00475;Wnt signaling pathway#P00057>Frizzled#P01428;Angiogenesis#P00005>FRP#P00237;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 MONDO|Ensembl=ENSMODG00000028751.2|UniProtKB=K7E0E2 K7E0E2 LOC100020659 PTHR42985:SF10 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 1 symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075 carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;lipid localization#GO:0010876;transmembrane transport#GO:0055085;fatty acid transport#GO:0015908;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;monocarboxylic acid transport#GO:0015718;sodium ion transport#GO:0006814;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000042916.1|UniProtKB=A0A5F8G298 A0A5F8G298 OR4D11 PTHR48002:SF68 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D10 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000050142.1|UniProtKB=A0A5F8G595 A0A5F8G595 PTHR11437:SF69 RIBONUCLEASE RIBONUCLEASE A-DOMAIN DOMAIN-CONTAINING PROTEIN nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 defense response#GO:0006952;response to external stimulus#GO:0009605;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to Gram-positive bacterium#GO:0050830;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 RNA metabolism protein#PC00031;endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000012643.2|UniProtKB=A0A5F8HFE1 A0A5F8HFE1 PTHR24070:SF174 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAL-A hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular response to stimulus#GO:0051716;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;Ras protein signal transduction#GO:0007265;regulation of secretion#GO:0051046;cell communication#GO:0007154;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 Ras Pathway#P04393>Ral#P04550 MONDO|Ensembl=ENSMODG00000005510.4|UniProtKB=F7G5P8 F7G5P8 EDC4 PTHR15598:SF5 ENHANCER OF MRNA-DECAPPING PROTEIN 4 ENHANCER OF MRNA-DECAPPING PROTEIN 4 molecular condensate scaffold activity#GO:0140693;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;RNA decapping#GO:0110154;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229 mRNA capping factor#PC00145 MONDO|Ensembl=ENSMODG00000023501.1|UniProtKB=F7EGN5 F7EGN5 LOC100010024 PTHR26453:SF156 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003809.3|UniProtKB=F6ZJ40 F6ZJ40 PTHR45881:SF3 CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED FORKHEAD BOX PROTEIN K2 MONDO|Ensembl=ENSMODG00000006801.4|UniProtKB=A0A5F8G5A1 A0A5F8G5A1 ACSM5 PTHR43605:SF6 ACYL-COENZYME A SYNTHETASE ACYL-COENZYME A SYNTHETASE ACSM5, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;transferase activity#GO:0016740;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 oxoacid metabolic process#GO:0043436;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;carboxylic acid biosynthetic process#GO:0046394;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;ligase#PC00142 MONDO|Ensembl=ENSMODG00000039242.1|UniProtKB=A0A5F8HIQ0 A0A5F8HIQ0 PTHR33426:SF30 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000009218.3|UniProtKB=F7EED9 F7EED9 RPLP1 PTHR45696:SF10 60S ACIDIC RIBOSOMAL PROTEIN P1 LARGE RIBOSOMAL SUBUNIT PROTEIN P1 kinase activator activity#GO:0019209;binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;enzyme activator activity#GO:0008047;structural constituent of ribosome#GO:0003735;protein kinase activator activity#GO:0030295;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;structural molecule activity#GO:0005198;protein kinase regulator activity#GO:0019887 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000019878.4|UniProtKB=F6WL14 F6WL14 SLC35C1 PTHR11132:SF255 SOLUTE CARRIER FAMILY 35 GDP-FUCOSE TRANSPORTER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;nucleotide-sugar transmembrane transporter activity#GO:0005338;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;nucleotide-sugar transmembrane transport#GO:0015780;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nitrogen compound transport#GO:0071705;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000021236.4|UniProtKB=F6TZX3 F6TZX3 XRN1 PTHR12341:SF7 5'->3' EXORIBONUCLEASE 5'-3' EXORIBONUCLEASE 1 RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;hydrolase activity#GO:0016787;RNA binding#GO:0003723;exonuclease activity#GO:0004527;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;exoribonuclease#PC00099 DNA replication#P00017>5' to 3' Exoribonulcease#P00535 MONDO|Ensembl=ENSMODG00000019921.5|UniProtKB=F7FUY1 F7FUY1 FNBP4 PTHR46697:SF1 FORMIN-BINDING PROTEIN 4 FORMIN-BINDING PROTEIN 4 MONDO|Ensembl=ENSMODG00000042056.1|UniProtKB=A0A5F8GHA7 A0A5F8GHA7 PTHR35252:SF1 RETINITIS PIGMENTOSA 9 PROTEIN RETINITIS PIGMENTOSA 9 PROTEIN MONDO|Ensembl=ENSMODG00000005137.4|UniProtKB=F7EQG7 F7EQG7 ANGPTL6 PTHR19143:SF209 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 6 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000013191.4|UniProtKB=F7FAC3 F7FAC3 SMARCE1 PTHR46232:SF1 SMARCE1 REGULATOR OF CHROMATIN SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1 DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;binding#GO:0005488 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000021354.4|UniProtKB=H9H7Z6 H9H7Z6 PTHR21711:SF0 MITOCHONDRIAL INNER MEMBRANE PROTEASE MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;metabolic process#GO:0008152;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein metabolic process#GO:0019538;proteolysis#GO:0006508 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000010241.4|UniProtKB=F6W6Q0 F6W6Q0 TLK2 PTHR22974:SF20 MIXED LINEAGE PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE TOUSLED-LIKE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 chromosome segregation#GO:0007059;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000016148.4|UniProtKB=F7D6Z0 F7D6Z0 NPC1L1 PTHR45727:SF3 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 NPC1-LIKE INTRACELLULAR CHOLESTEROL TRANSPORTER 1 alcohol binding#GO:0043178;lipid binding#GO:0008289;steroid binding#GO:0005496;cholesterol binding#GO:0015485;binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934 homeostatic process#GO:0042592;lipid transport#GO:0006869;digestion#GO:0007586;multicellular organismal process#GO:0032501;macromolecule localization#GO:0033036;lipid homeostasis#GO:0055088;organic hydroxy compound transport#GO:0015850;system process#GO:0003008;localization#GO:0051179;sterol transport#GO:0015918;cholesterol homeostasis#GO:0042632;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;transport#GO:0006810;lipid localization#GO:0010876 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000019537.3|UniProtKB=F6UUJ8 F6UUJ8 RSPO4 PTHR46987:SF6 NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN R-SPONDIN-4 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000024451.2|UniProtKB=F6Z8M9 F6Z8M9 PTHR11711:SF357 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 1 nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf1#P00923 MONDO|Ensembl=ENSMODG00000011196.4|UniProtKB=F6SRH5 F6SRH5 NEK4 PTHR24361:SF859 MITOGEN-ACTIVATED KINASE KINASE KINASE SERINE_THREONINE-PROTEIN KINASE NEK4 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of transmembrane transport#GO:0034762;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;regulation of monoatomic cation transmembrane transport#GO:1904062;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of monoatomic ion transport#GO:0043269;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of canonical Wnt signaling pathway#GO:0060828;response to stress#GO:0006950;positive regulation of Wnt signaling pathway#GO:0030177 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000008597.4|UniProtKB=F7BTZ9 F7BTZ9 C3H22orf31 PTHR15578:SF0 CHROMOSOME 8 C22ORF31 HOMOLOG CHROMOSOME 22 OPEN READING FRAME 31 MONDO|Ensembl=ENSMODG00000000012.4|UniProtKB=F6YTC5 F6YTC5 SPOCK2 PTHR13866:SF18 SPARC OSTEONECTIN TESTICAN-2 enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cation binding#GO:0043169 regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of biological process#GO:0050789 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 MONDO|Ensembl=ENSMODG00000025694.3|UniProtKB=F6TJJ4 F6TJJ4 LOC100017283 PTHR12015:SF103 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 4-LIKE protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009 humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;cell surface receptor signaling pathway#GO:0007166;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;response to chemical#GO:0042221;response to cytokine#GO:0034097;taxis#GO:0042330;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;response to peptide#GO:1901652;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;positive regulation of locomotion#GO:0040017;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;cell migration#GO:0016477;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of cell migration#GO:0030335;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;regulation of cell motility#GO:2000145;chemokine-mediated signaling pathway#GO:0070098;cell chemotaxis#GO:0060326;cytokine-mediated signaling pathway#GO:0019221;chemotaxis#GO:0006935;inflammatory response#GO:0006954;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000011400.4|UniProtKB=F6S6M6 F6S6M6 CFAP57 PTHR32215:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000004246.4|UniProtKB=F6UB43 F6UB43 LRRC19 PTHR31450:SF4 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 19 LRRC19 FAMILY MEMBER LEUCINE-RICH REPEAT-CONTAINING PROTEIN 19 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signaling#GO:0023052;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;toll-like receptor signaling pathway#GO:0002224;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;regulation of response to external stimulus#GO:0032101;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;positive regulation of signal transduction#GO:0009967;cell communication#GO:0007154;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;activation of innate immune response#GO:0002218;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stress#GO:0080134 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000001109.4|UniProtKB=F7DPF6 F7DPF6 NDRG1 PTHR11034:SF18 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG1 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000014607.4|UniProtKB=F6ZE52 F6ZE52 RFTN1 PTHR17601:SF3 RAFTLIN-RELATED RAFTLIN MONDO|Ensembl=ENSMODG00000016488.3|UniProtKB=A0A5F8HJM1 A0A5F8HJM1 PTHR43939:SF130 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 4 cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;mitotic cell cycle process#GO:1903047;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;sister chromatid segregation#GO:0000819;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle#GO:0007049;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;organelle fission#GO:0048285;sexual reproduction#GO:0019953;nuclear division#GO:0000280 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensin complex#GO:0000796;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000006014.3|UniProtKB=F7AJT1 F7AJT1 ACYP1 PTHR10029:SF3 ACYLPHOSPHATASE ACYLPHOSPHATASE-1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000049065.1|UniProtKB=A0A5F8H9F0 A0A5F8H9F0 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010432.4|UniProtKB=A0A5F8H1A7 A0A5F8H1A7 ANK1 PTHR24133:SF38 ANKYRIN DOMAIN-CONTAINING ANKYRIN-1 molecular adaptor activity#GO:0060090;cytoskeletal adaptor activity#GO:0008093;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transmembrane transporter binding#GO:0044325;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 protein localization to plasma membrane#GO:0072659;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013980.4|UniProtKB=F6R5Z0 F6R5Z0 UPK1A PTHR19282:SF25 TETRASPANIN UROPLAKIN-1A membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000023680.2|UniProtKB=F7CQ16 F7CQ16 PTHR43000:SF54 DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED UDP-D-GLUCOSE 4,6-DEHYDRATASE catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 dehydratase#PC00091 O-antigen biosynthesis#P02757>dTDP-glucose 4,6-dehydratase#P03045 MONDO|Ensembl=ENSMODG00000012297.2|UniProtKB=F7EJ94 F7EJ94 HCAR2 PTHR46048:SF6 HYDROXYCARBOXYLIC ACID RECEPTOR 2 HYDROXYCARBOXYLIC ACID RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020427.4|UniProtKB=F7ARM9 F7ARM9 SEC11C PTHR10806:SF12 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11C catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;peptidase complex#GO:1905368;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 serine protease#PC00203 Vasopressin synthesis#P04395>Signal Peptidase#P04589;Endothelin signaling pathway#P00019>signal peptidase#P00573 MONDO|Ensembl=ENSMODG00000000754.4|UniProtKB=F6T8H0 F6T8H0 WLS PTHR13449:SF2 INTEGRAL MEMBRANE PROTEIN GPR177 PROTEIN WNTLESS HOMOLOG binding#GO:0005488;protein binding#GO:0005515;Wnt-protein binding#GO:0017147 regulation of biological process#GO:0050789;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;signaling#GO:0023052;signal release#GO:0023061;secretion by cell#GO:0032940;protein transport#GO:0015031;protein secretion#GO:0009306;localization#GO:0051179;cell communication#GO:0007154;cellular localization#GO:0051641;secretion#GO:0046903;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;establishment of localization#GO:0051234 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000010146.4|UniProtKB=A0A5F8GJ07 A0A5F8GJ07 RPH3AL PTHR45729:SF4 RABPHILIN, ISOFORM A RAB EFFECTOR NOC2 regulation of secretion#GO:0051046;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;positive regulation of secretion#GO:0051047;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of secretion by cell#GO:1903532;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627 MONDO|Ensembl=ENSMODG00000008702.3|UniProtKB=F6PWL5 F6PWL5 GALNT10 PTHR11675:SF41 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 10 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000012398.4|UniProtKB=F6PN02 F6PN02 ABCB9 PTHR24221:SF242 ATP-BINDING CASSETTE SUB-FAMILY B ABC-TYPE OLIGOPEPTIDE TRANSPORTER ABCB9 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000010682.3|UniProtKB=F7C164 F7C164 DGAT1 PTHR10408:SF7 STEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 lipid biosynthetic process#GO:0008610;triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;neutral lipid metabolic process#GO:0006638;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 MONDO|Ensembl=ENSMODG00000001064.4|UniProtKB=F6YQZ8 F6YQZ8 FBXL5 PTHR13318:SF19 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 5 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 catalytic complex#GO:1902494;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 MONDO|Ensembl=ENSMODG00000011475.4|UniProtKB=H9H6I2 H9H6I2 ARRDC2 PTHR11188:SF48 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 2 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000010938.2|UniProtKB=F7EP47 F7EP47 LOC100020820 PTHR47979:SF111 DRAB11-RELATED RAB42, MEMBER RAS ONCO FAMILY hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553 localization#GO:0051179;vacuole organization#GO:0007033;organelle assembly#GO:0070925;endocytosis#GO:0006897;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle organization#GO:0016050;phagolysosome assembly#GO:0001845;phagocytosis#GO:0006909;lytic vacuole organization#GO:0080171;transport#GO:0006810;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membrane fusion#GO:0061025;lysosome organization#GO:0007040;cellular process#GO:0009987 G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000024920.2|UniProtKB=F6SFC1 F6SFC1 PTHR46752:SF1 G-PROTEIN COUPLED RECEPTOR 39 G PROTEIN-COUPLED RECEPTOR 39 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;biological regulation#GO:0065007;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000012202.4|UniProtKB=F7CE83 F7CE83 SLC7A10 PTHR11785:SF73 AMINO ACID TRANSPORTER ASC-TYPE AMINO ACID TRANSPORTER 1 amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;L-amino acid transmembrane transporter activity#GO:0015179 alanine transport#GO:0032328;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;amino acid transport#GO:0006865;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000050949.1|UniProtKB=A0A5F8HJ84 A0A5F8HJ84 PTHR23087:SF12 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-14 chromatin binding#GO:0003682;binding#GO:0005488 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000000894.3|UniProtKB=F7A7I8 F7A7I8 CYB5R1 PTHR19370:SF74 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE 1 oxidoreductase activity, acting on NAD(P)H#GO:0016651;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;reductase#PC00198 MONDO|Ensembl=ENSMODG00000002746.3|UniProtKB=F6Z6L9 F6Z6L9 PTHR24356:SF140 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE_THREONINE-PROTEIN KINASE 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000015628.4|UniProtKB=F7FEU5 F7FEU5 ABCA12 PTHR19229:SF29 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA GLUCOSYLCERAMIDE TRANSPORTER ABCA12 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;signaling receptor binding#GO:0005102;binding#GO:0005488;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;protein binding#GO:0005515;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 transport#GO:0006810;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;localization#GO:0051179 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000018004.1|UniProtKB=Q9TUI7 Q9TUI7 APOBEC1 PTHR13857:SF26 MRNA EDITING ENZYME C-U-EDITING ENZYME APOBEC-1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824;RNA binding#GO:0003723;hydrolase activity#GO:0016787;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;base conversion or substitution editing#GO:0016553;metabolic process#GO:0008152;RNA modification#GO:0009451;nucleobase-containing compound metabolic process#GO:0006139;cytidine to uridine editing#GO:0016554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000003873.3|UniProtKB=F7DTF3 F7DTF3 PABPN1L PTHR23236:SF27 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EMBRYONIC POLYADENYLATE-BINDING PROTEIN 2 binding#GO:0005488;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000004420.4|UniProtKB=F6SD55 F6SD55 ABCF2 PTHR19211:SF15 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 2 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ATP binding#GO:0005524;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265 translation elongation factor#PC00222 MONDO|Ensembl=ENSMODG00000014470.4|UniProtKB=F7A5G5 F7A5G5 SLC25A48 PTHR45624:SF7 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 48 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000011018.4|UniProtKB=F7A1N0 F7A1N0 DSG3 PTHR24025:SF3 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-3 calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell-cell junction#GO:0005911 cadherin#PC00057 MONDO|Ensembl=ENSMODG00000036769.1|UniProtKB=F7E8V8 F7E8V8 LOC100618419 PTHR26450:SF195 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018234.4|UniProtKB=A0A5F8H5A0 A0A5F8H5A0 BORCS5 PTHR31634:SF2 BLOC-1-RELATED COMPLEX SUBUNIT 5 BLOC-1-RELATED COMPLEX SUBUNIT 5 transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;regulation of localization#GO:0032879;regulation of transport#GO:0051049;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;biological regulation#GO:0065007;lysosome localization#GO:0032418;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;regulation of microtubule-based process#GO:0032886;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;regulation of cellular process#GO:0050794;regulation of microtubule-based movement#GO:0060632;regulation of biological process#GO:0050789 vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;vacuolar membrane#GO:0005774;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;presynapse#GO:0098793;lysosomal membrane#GO:0005765;secretory vesicle#GO:0099503;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasmic side of membrane#GO:0098562;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;lytic vacuole#GO:0000323;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;side of membrane#GO:0098552 MONDO|Ensembl=ENSMODG00000010681.4|UniProtKB=H9H6E5 H9H6E5 HKDC1 PTHR19443:SF28 HEXOKINASE HEXOKINASE HKDC1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;hexokinase activity#GO:0004396;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 intracellular chemical homeostasis#GO:0055082;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate metabolic process#GO:0006753;homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;glucose 6-phosphate metabolic process#GO:0051156;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;chemical homeostasis#GO:0048878;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;intracellular glucose homeostasis#GO:0001678;oxoacid metabolic process#GO:0043436;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;carbohydrate homeostasis#GO:0033500;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;cellular homeostasis#GO:0019725;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine nucleoside diphosphate catabolic process#GO:0009137;glucose homeostasis#GO:0042593;nucleobase-containing small molecule metabolic process#GO:0055086;ADP catabolic process#GO:0046032;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;pyruvate metabolic process#GO:0006090;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;monocarboxylic acid metabolic process#GO:0032787 outer membrane#GO:0019867;intracellular organelle#GO:0043229;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic side of membrane#GO:0098562;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cytosol#GO:0005829;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 Glycolysis#P00024>Hexokinase#P00677;Fructose galactose metabolism#P02744>Hexokinase#P02966;Pentose phosphate pathway#P02762>Hexokinase#P03079 MONDO|Ensembl=ENSMODG00000004947.3|UniProtKB=F7ATN5 F7ATN5 MAB21L3 PTHR10656:SF30 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MAB-21-LIKE 3 transferase#PC00220;nucleotidyltransferase#PC00174 MONDO|Ensembl=ENSMODG00000007255.3|UniProtKB=F7EYD9 F7EYD9 OR11H4 PTHR24242:SF381 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11H4 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000011392.5|UniProtKB=F6SNP0 F6SNP0 WDR75 PTHR44215:SF1 WD REPEAT-CONTAINING PROTEIN 75 WD REPEAT-CONTAINING PROTEIN 75 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase I#GO:0045943;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase I#GO:0006356;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000050254.1|UniProtKB=K7E1H9 K7E1H9 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000002395.3|UniProtKB=F7EZU4 F7EZU4 PTHR46047:SF1 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 2 protein binding#GO:0005515;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000023499.2|UniProtKB=F7EGR1 F7EGR1 PTHR26453:SF156 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002868.4|UniProtKB=F7E2A3 F7E2A3 ERP29 PTHR12211:SF0 ENDOPLASMIC RETICULUM PROTEIN ERP29 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 29 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 protein metabolic process#GO:0019538;regulation of cellular response to stress#GO:0080135;regulation of intracellular signal transduction#GO:1902531;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;protein folding#GO:0006457;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;protein maturation#GO:0051604;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000008781.4|UniProtKB=F6RFP8 F6RFP8 ARHGAP21 PTHR23175:SF16 PDZ DOMAIN-CONTAINING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 21 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 cytoskeleton-dependent intracellular transport#GO:0030705;endomembrane system organization#GO:0010256;organelle transport along microtubule#GO:0072384;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;cellular component organization#GO:0016043;Golgi organization#GO:0007030;localization#GO:0051179;cellular localization#GO:0051641;organelle localization#GO:0051640;microtubule-based transport#GO:0099111 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000040780.1|UniProtKB=A0A5F8H351 A0A5F8H351 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005479.4|UniProtKB=F7CFZ9 F7CFZ9 LOC103096308 PTHR45736:SF11 ZINC FINGER MYM-TYPE PROTEIN GLUTAMINE-RICH PROTEIN 1-LIKE DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000020856.4|UniProtKB=A0A5F8GPL0 A0A5F8GPL0 CLPTM1 PTHR21347:SF14 CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED LIPID SCRAMBLASE CLPTM1-RELATED endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000042308.1|UniProtKB=A0A5F8GLQ7 A0A5F8GLQ7 VN2R511 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000014153.4|UniProtKB=F6X316 F6X316 SLC35B4 PTHR10778:SF4 SOLUTE CARRIER FAMILY 35 MEMBER B NUCLEOTIDE SUGAR TRANSPORTER SLC35B4 nucleotide-sugar transmembrane transporter activity#GO:0005338;carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nucleotide-sugar transmembrane transport#GO:0015780 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000012189.4|UniProtKB=A0A5F8GSP8 A0A5F8GSP8 PTHR11699:SF233 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;cellular detoxification of aldehyde#GO:0110095;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887;cellular response to oxygen-containing compound#GO:1901701;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;aldehyde catabolic process#GO:0046185;response to chemical#GO:0042221;metabolic process#GO:0008152 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 MONDO|Ensembl=ENSMODG00000014054.4|UniProtKB=A0A5F8H3J1 A0A5F8H3J1 RBMX PTHR48034:SF18 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED RNA-BINDING MOTIF PROTEIN, X CHROMOSOME RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000020860.4|UniProtKB=F6R080 F6R080 TOMM40 PTHR10802:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 HOMOLOG transmembrane protein transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839 mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane translocase complex#GO:0005742;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000009731.4|UniProtKB=F6XAH5 F6XAH5 FUT8 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 MONDO|Ensembl=ENSMODG00000015728.4|UniProtKB=F7B542 F7B542 MEGF10 PTHR24035:SF136 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 10 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular process#GO:0009987;cellular component organization#GO:0016043;membrane organization#GO:0061024;cell migration#GO:0016477;endocytosis#GO:0006897;cell motility#GO:0048870;transport#GO:0006810;membrane invagination#GO:0010324;phagocytosis#GO:0006909;import into cell#GO:0098657;establishment of localization#GO:0051234;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;apoptotic cell clearance#GO:0043277 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000011641.4|UniProtKB=F6TJ68 F6TJ68 TPR PTHR18898:SF8 NUCLEOPROTEIN TPR-RELATED NUCLEOPROTEIN TPR structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 metabolic process#GO:0008152;regulation of mitotic spindle assembly#GO:1901673;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cell cycle process#GO:0010564;gene expression#GO:0010467;regulation of mitotic spindle organization#GO:0060236;regulation of spindle assembly#GO:0090169;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;regulation of organelle assembly#GO:1902115;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleocytoplasmic transport#GO:0006913;regulation of microtubule-based process#GO:0032886;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;localization#GO:0051179;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA transport#GO:0050658;RNA localization#GO:0006403;regulation of cellular process#GO:0050794;regulation of spindle organization#GO:0090224;regulation of cytoskeleton organization#GO:0051493;nucleobase-containing compound transport#GO:0015931 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634 primary active transporter#PC00068 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000021080.4|UniProtKB=F6V150 F6V150 HUNK PTHR24346:SF80 MAP/MICROTUBULE AFFINITY-REGULATING KINASE HORMONALLY UP-REGULATED NEU TUMOR-ASSOCIATED KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000019511.4|UniProtKB=F6VDB2 F6VDB2 DDX4 PTHR47958:SF11 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organismal reproductive process#GO:0048609;developmental process#GO:0032502;sexual reproduction#GO:0019953;cell differentiation#GO:0030154;gamete generation#GO:0007276;reproductive process#GO:0022414;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;nucleus#GO:0005634 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000021244.4|UniProtKB=F6TJF4 F6TJF4 SLC9A9 PTHR10110:SF61 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 9 secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079 sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;recycling endosome#GO:0055037;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000014803.4|UniProtKB=A0A5F8GRV1 A0A5F8GRV1 ATP6V1C2 PTHR10137:SF4 V-TYPE PROTON ATPASE SUBUNIT C V-TYPE PROTON ATPASE SUBUNIT C 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;monoatomic cation transmembrane transporter activity#GO:0008324 proton-transporting two-sector ATPase complex#GO:0016469;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000010133.4|UniProtKB=A0A5F8GZI9 A0A5F8GZI9 TCF7L2 PTHR10373:SF32 TRANSCRIPTION FACTOR 7 FAMILY MEMBER TRANSCRIPTION FACTOR 7-LIKE 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 cellular response to stimulus#GO:0051716;Wnt signaling pathway#GO:0016055;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of cell communication#GO:0010646;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;regulation of carbohydrate metabolic process#GO:0006109;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;regulation of canonical Wnt signaling pathway#GO:0060828;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;cell surface receptor signaling pathway#GO:0007166 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Wnt signaling pathway#P00057>TCF#P01437;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Angiogenesis#P00005>TCF#P00242;Cadherin signaling pathway#P00012>TCF/LEF#P00465 MONDO|Ensembl=ENSMODG00000013064.4|UniProtKB=F7FQ08 F7FQ08 GRHL3 PTHR11037:SF6 TRANSCRIPTION FACTOR CP2 GRAINYHEAD-LIKE PROTEIN 3 HOMOLOG transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000000252.4|UniProtKB=H9H5V2 H9H5V2 KLHL21 PTHR24412:SF255 KELCH PROTEIN KELCH-LIKE PROTEIN 21 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000011080.4|UniProtKB=F7E5V6 F7E5V6 UBIAD1 PTHR13929:SF17 1,4-DIHYDROXY-2-NAPHTHOATE OCTAPRENYLTRANSFERASE UBIA PRENYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 menaquinone biosynthetic process#GO:0009234;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;vitamin K metabolic process#GO:0042373;ketone metabolic process#GO:0042180;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152 transferase#PC00220 MONDO|Ensembl=ENSMODG00000038638.1|UniProtKB=F7B7R1 F7B7R1 monDomV1R1282 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017993.4|UniProtKB=F7B8E4 F7B8E4 PTHR21356:SF2 ARMADILLO REPEAT CONTAINING 2 ARMADILLO REPEAT-CONTAINING PROTEIN 2 cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;microtubule-based process#GO:0007017;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;spermatogenesis#GO:0007283;developmental process#GO:0032502;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281 MONDO|Ensembl=ENSMODG00000000525.4|UniProtKB=F6Y4Y9 F6Y4Y9 TUBGCP5 PTHR19302:SF33 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 5 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;cytoplasmic microtubule organization#GO:0031122;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000017128.4|UniProtKB=F6U3D0 F6U3D0 NSMF PTHR32061:SF4 NMDA RECEPTOR SYNAPTONUCLEAR SIGNALING AND NEURONAL MIGRATION FACTOR NMDA RECEPTOR SYNAPTONUCLEAR SIGNALING AND NEURONAL MIGRATION FACTOR positive regulation of cell migration#GO:0030335;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell migration#GO:0030334;regulation of neuron migration#GO:2001222;positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000019966.2|UniProtKB=F6SRP0 F6SRP0 LOC100617710 PTHR48002:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010557.4|UniProtKB=F6YRK0 F6YRK0 C1H10orf90 PTHR21553:SF24 ALMS1-RELATED (E2-INDEPENDENT) E3 UBIQUITIN-CONJUGATING ENZYME FATS ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of microtubule-based process#GO:0032886;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of organelle assembly#GO:1902115 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813 MONDO|Ensembl=ENSMODG00000000987.4|UniProtKB=A0A5F8GWM7 A0A5F8GWM7 PROM1 PTHR22730:SF3 PROMININ PROM PROTEIN PROMININ-1 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;visual system development#GO:0150063;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887;cell differentiation#GO:0030154;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;camera-type eye morphogenesis#GO:0048593;sensory system development#GO:0048880;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;retina development in camera-type eye#GO:0060041;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;sensory organ development#GO:0007423;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 cytoskeleton#GO:0005856;apical part of cell#GO:0045177;membraneless organelle#GO:0043228;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;extracellular region#GO:0005576;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;apical plasma membrane#GO:0016324;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 MONDO|Ensembl=ENSMODG00000015925.5|UniProtKB=F6ZQS8 F6ZQS8 ESPNL PTHR24153:SF0 ESPIN ESPIN-LIKE PROTEIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 sensory perception of sound#GO:0007605;actin cytoskeleton organization#GO:0030036;cellular component organization#GO:0016043;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;supramolecular fiber organization#GO:0097435;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;actin filament-based process#GO:0030029;nervous system process#GO:0050877;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;system process#GO:0003008 intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;stereocilium#GO:0032420;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin-based cell projection#GO:0098858;neuron projection#GO:0043005;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000011589.4|UniProtKB=A0A5F8G7J5 A0A5F8G7J5 MFSD6 PTHR16172:SF43 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6 antigen processing and presentation#GO:0019882;immune system process#GO:0002376 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000008684.3|UniProtKB=F6PXW4 F6PXW4 PTHR22811:SF38 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 4 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;cellular component organization#GO:0016043;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000001566.4|UniProtKB=F7FYV2 F7FYV2 JMJD6 PTHR12480:SF32 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD BIFUNCTIONAL ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD6 transport#GO:0006810;phagocytosis#GO:0006909;localization#GO:0051179;endocytosis#GO:0006897;import into cell#GO:0098657;establishment of localization#GO:0051234 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000013561.4|UniProtKB=F7C2W9 F7C2W9 ETV7 PTHR11849:SF77 ETS TRANSCRIPTION FACTOR ETV7 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000021220.4|UniProtKB=F6U1C7 F6U1C7 LOC100021085 PTHR10686:SF37 FOLATE TRANSPORTER THIAMINE TRANSPORTER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000046009.1|UniProtKB=A0A5F8G3V9 A0A5F8G3V9 AUP1 PTHR15486:SF103 ANCIENT UBIQUITOUS PROTEIN LIPID DROPLET-REGULATING VLDL ASSEMBLY FACTOR AUP1 catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004398.5|UniProtKB=A0A5F8GSL4 A0A5F8GSL4 EPRS1 PTHR43382:SF2 PROLYL-TRNA SYNTHETASE BIFUNCTIONAL GLUTAMATE_PROLINE--TRNA LIGASE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 MONDO|Ensembl=ENSMODG00000049860.1|UniProtKB=F6W0F0 F6W0F0 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019666.4|UniProtKB=H9H7E0 H9H7E0 PTHR48094:SF18 PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED GLUTAMINE AMIDOTRANSFERASE-LIKE CLASS 1 DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000038400.1|UniProtKB=A0A5F8H7N6 A0A5F8H7N6 PTHR16201:SF53 SEVEN TRANSMEMBRANE PROTEIN 1-RELATED TRANSMEMBRANE PROTEIN 44 L-amino acid transmembrane transporter activity#GO:0015179;basic amino acid transmembrane transporter activity#GO:0015174;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;homeostatic process#GO:0042592;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;establishment of localization#GO:0051234;vacuolar transmembrane transport#GO:0034486;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;amino acid transport#GO:0006865;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 vacuole#GO:0005773;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000001375.3|UniProtKB=F7FJC6 F7FJC6 SP8 PTHR23235:SF25 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP8 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 C2H2 zinc finger transcription factor#PC00248 Huntington disease#P00029>Sp1#P00803 MONDO|Ensembl=ENSMODG00000022672.2|UniProtKB=H9H8C4 H9H8C4 PTHR12473:SF17 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-3 deubiquitinase activity#GO:0101005;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 MONDO|Ensembl=ENSMODG00000036908.1|UniProtKB=A0A5F8GI52 A0A5F8GI52 KDELR1 PTHR10585:SF61 ER LUMEN PROTEIN RETAINING RECEPTOR ER LUMEN PROTEIN-RETAINING RECEPTOR 1 signal sequence receptor activity#GO:0005048 cellular localization#GO:0051641;protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cis-Golgi network#GO:0005801;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000016289.4|UniProtKB=F7AU44 F7AU44 SLC5A11 PTHR11819:SF171 SOLUTE CARRIER FAMILY 5 SODIUM_MYO-INOSITOL COTRANSPORTER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000001864.4|UniProtKB=F6SNH9 F6SNH9 PDIA4 PTHR18929:SF210 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A4 catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;catalytic activity, acting on a protein#GO:0140096;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853 macromolecule biosynthetic process#GO:0009059;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000004910.3|UniProtKB=F7C1Q4 F7C1Q4 JAG1 PTHR24044:SF448 NOTCH LIGAND FAMILY MEMBER PROTEIN JAGGED-1 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Serrate#P01104;Angiogenesis#P00005>Delta/Serrate#P00226;Notch signaling pathway#P00045>Next#P01103 MONDO|Ensembl=ENSMODG00000017198.4|UniProtKB=F6Z3Z1 F6Z3Z1 IL6R PTHR23036:SF98 CYTOKINE RECEPTOR INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 cell surface receptor signaling pathway#GO:0007166;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;response to peptide#GO:1901652;positive regulation of cell population proliferation#GO:0008284;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 MONDO|Ensembl=ENSMODG00000016855.4|UniProtKB=F6QH03 F6QH03 PTHR24020:SF39 COLLAGEN ALPHA COLLAGEN ALPHA-1(XX) CHAIN extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000016004.5|UniProtKB=A0A5F8GMM4 A0A5F8GMM4 TRIM15 PTHR24103:SF259 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM15 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000019698.2|UniProtKB=F6TCJ3 F6TCJ3 LOC100017044 PTHR48001:SF151 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037386.1|UniProtKB=A0A5F8H7B9 A0A5F8H7B9 PTHR24393:SF100 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 345-RELATED transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000009876.4|UniProtKB=F6VTV0 F6VTV0 INTS14 PTHR13532:SF3 FAMILY NOT NAMED INTEGRATOR COMPLEX SUBUNIT 14 MONDO|Ensembl=ENSMODG00000042972.1|UniProtKB=A0A5F8G5R2 A0A5F8G5R2 ZNF500 PTHR23226:SF74 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 500 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011673.4|UniProtKB=F7GEF7 F7GEF7 TKTL2 PTHR43195:SF4 TRANSKETOLASE TRANSKETOLASE-LIKE PROTEIN 2 ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;cation binding#GO:0043169;transketolase activity#GO:0004802;transketolase or transaldolase activity#GO:0016744;transferase activity#GO:0016740;catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transketolase#PC00221 MONDO|Ensembl=ENSMODG00000047680.1|UniProtKB=A0A5F8GIQ3 A0A5F8GIQ3 VN2R613 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003118.5|UniProtKB=A0A5F8GE21 A0A5F8GE21 RABGGTA PTHR11129:SF2 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT ALPHA catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity, acting on a protein#GO:0140096 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 acyltransferase#PC00042;transferase#PC00220 MONDO|Ensembl=ENSMODG00000042493.1|UniProtKB=A0A5F8G2H3 A0A5F8G2H3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001393.3|UniProtKB=A0A5F8HLB7 A0A5F8HLB7 ATG4C PTHR22624:SF38 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4C hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;protein-phosphatidylethanolamide deconjugating activity#GO:0019786;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 autophagosome assembly#GO:0000045;mitophagy#GO:0000423;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;macroautophagy#GO:0016236;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;autophagy#GO:0006914;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;protein metabolic process#GO:0019538;organelle assembly#GO:0070925;proteolysis#GO:0006508;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000006694.4|UniProtKB=F7F266 F7F266 CALN1 PTHR46311:SF3 CALCIUM-BINDING PROTEIN 8-RELATED CALCIUM-BINDING PROTEIN 8 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000036821.1|UniProtKB=A0A5F8GDB0 A0A5F8GDB0 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000015606.3|UniProtKB=F6Z5J6 F6Z5J6 GGCX PTHR12639:SF6 VITAMIN K-DEPENDENT GAMMA-CARBOXYLASE VITAMIN K-DEPENDENT GAMMA-CARBOXYLASE carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;catalytic activity#GO:0003824;binding#GO:0005488;carboxy-lyase activity#GO:0016831;lyase activity#GO:0016829 metabolic process#GO:0008152;ketone metabolic process#GO:0042180;vitamin K metabolic process#GO:0042373;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000006486.4|UniProtKB=F7F2K0 F7F2K0 PTHR22426:SF1 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 LYSINE-RICH NUCLEOLAR PROTEIN 1 MONDO|Ensembl=ENSMODG00000011412.4|UniProtKB=A0A5F8GDT6 A0A5F8GDT6 EBNA1BP2 PTHR13028:SF0 RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED RRNA-PROCESSING PROTEIN EBP2-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000024140.1|UniProtKB=F7GJQ6 F7GJQ6 PTHR10177:SF444 CYCLINS CYCLIN-A2 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772 transferase complex#GO:1990234;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin A#P04666 MONDO|Ensembl=ENSMODG00000011874.4|UniProtKB=F6XSG8 F6XSG8 BRINP3 PTHR15564:SF2 MACPF DOMAIN-CONTAINING PROTEIN BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 3 neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of mitotic cell cycle#GO:0007346;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;negative regulation of cell cycle#GO:0045786;neuron differentiation#GO:0030182;nervous system development#GO:0007399;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;negative regulation of mitotic cell cycle#GO:0045930;response to oxygen-containing compound#GO:1901700;generation of neurons#GO:0048699;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;regulation of cell cycle#GO:0051726;central nervous system development#GO:0007417;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 dendritic tree#GO:0097447;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622;cell body#GO:0044297;neuron projection#GO:0043005;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000003698.4|UniProtKB=F7FAF3 F7FAF3 TBRG1 PTHR22715:SF0 TRANSFORMING GROWTH FACTOR BETA REGULATED GENE 1 TRANSFORMING GROWTH FACTOR BETA REGULATOR 1 regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 intercellular signal molecule#PC00207;growth factor#PC00112 MONDO|Ensembl=ENSMODG00000051428.1|UniProtKB=F7C951 F7C951 LOC100023657 PTHR26454:SF165 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6T1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017810.3|UniProtKB=F6ZY07 F6ZY07 CSF3R PTHR23036:SF101 CYTOKINE RECEPTOR INTERLEUKIN-13 RECEPTOR SUBUNIT ALPHA-2 cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515 cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;response to peptide#GO:1901652 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 MONDO|Ensembl=ENSMODG00000001336.4|UniProtKB=F7FWC2 F7FWC2 FBXO7 PTHR15537:SF2 F-BOX ONLY PROTEIN 7 F-BOX ONLY PROTEIN 7 MONDO|Ensembl=ENSMODG00000048658.1|UniProtKB=A0A5F8GNQ8 A0A5F8GNQ8 LOC100021720 PTHR26450:SF59 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007658.2|UniProtKB=F7FZB1 F7FZB1 PTHR48002:SF112 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4Q3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003249.4|UniProtKB=F6TH96 F6TH96 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signaling#GO:0023052;biological regulation#GO:0065007;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000003639.4|UniProtKB=F7BM29 F7BM29 LMOD3 PTHR10901:SF3 TROPOMODULIN LEIOMODIN-3 protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 developmental process#GO:0032502;muscle contraction#GO:0006936;system process#GO:0003008;actin filament organization#GO:0007015;cellular developmental process#GO:0048869;multicellular organismal process#GO:0032501;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154 M band#GO:0031430;intracellular organelle#GO:0043229;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;A band#GO:0031672;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;sarcomere#GO:0030017;membraneless organelle#GO:0043228;contractile muscle fiber#GO:0043292;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000007528.4|UniProtKB=F7GJR3 F7GJR3 SLC26A7 PTHR11814:SF75 SULFATE TRANSPORTER ANION EXCHANGE TRANSPORTER carboxylic acid transmembrane transporter activity#GO:0046943;chloride transmembrane transporter activity#GO:0015108;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion transmembrane transporter activity#GO:0015075;dicarboxylic acid transmembrane transporter activity#GO:0005310;active transmembrane transporter activity#GO:0022804 monoatomic anion transmembrane transport#GO:0098656;dicarboxylic acid transport#GO:0006835;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000000079.4|UniProtKB=F7E3L9 F7E3L9 LOC100012477 PTHR31488:SF6 DPY-19-LIKE 1, LIKE (H. SAPIENS) C-MANNOSYLTRANSFERASE DPY19L2-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030 anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;spermatid differentiation#GO:0048515;sexual reproduction#GO:0019953;spermatid development#GO:0007286;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell development#GO:0048468;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;male gamete generation#GO:0048232;cellular process#GO:0009987 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;nuclear inner membrane#GO:0005637;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;nucleus#GO:0005634;membrane#GO:0016020;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000013014.4|UniProtKB=F7C7K6 F7C7K6 CIMIP7 PTHR35539:SF1 CDNA SEQUENCE BC048562 CILIARY MICROTUBULE INNER PROTEIN 7 MONDO|Ensembl=ENSMODG00000043771.1|UniProtKB=A0A5F8GET5 A0A5F8GET5 C6H11orf86 PTHR31831:SF1 HYPOTHETICAL PROTEIN LOC689065 SIMILAR TO HUMAN CHROMOSOME 11 OPEN READING FRAME 86 MONDO|Ensembl=ENSMODG00000000611.4|UniProtKB=F7GG72 F7GG72 PTHR11337:SF14 MUCIN/PORIMIN PORIMIN intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000018033.4|UniProtKB=F6ZWH6 F6ZWH6 POPDC3 PTHR12101:SF18 POPEYE DOMAIN CONTAINING PROTEIN POPEYE DOMAIN-CONTAINING PROTEIN 3 ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 cellular developmental process#GO:0048869;regulation of membrane potential#GO:0042391;animal organ development#GO:0048513;multicellular organism development#GO:0007275;striated muscle cell differentiation#GO:0051146;developmental process#GO:0032502;multicellular organismal process#GO:0032501;heart development#GO:0007507;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;anatomical structure development#GO:0048856;regulation of biological quality#GO:0065008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;muscle structure development#GO:0061061;circulatory system development#GO:0072359;cell differentiation#GO:0030154;muscle cell differentiation#GO:0042692 apical junction complex#GO:0043296;cell junction#GO:0030054;sarcolemma#GO:0042383;tight junction#GO:0070160;anchoring junction#GO:0070161;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000025207.3|UniProtKB=F7BFN1 F7BFN1 PTHR33426:SF30 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000015033.4|UniProtKB=F7BXB4 F7BXB4 EZH1 PTHR45747:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) HISTONE-LYSINE N-METHYLTRANSFERASE EZH1 binding#GO:0005488;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;chromatin binding#GO:0003682;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000000458.4|UniProtKB=A0A5F8G5H3 A0A5F8G5H3 INSIG2 PTHR15301:SF10 INSULIN-INDUCED GENE 1 INSULIN-INDUCED GENE 2 PROTEIN response to endogenous stimulus#GO:0009719;cellular response to endogenous stimulus#GO:0071495;small molecule metabolic process#GO:0044281;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;negative regulation of intracellular signal transduction#GO:1902532;regulation of cellular response to stress#GO:0080135;response to stress#GO:0006950;response to hormone#GO:0009725;response to lipid#GO:0033993;response to chemical#GO:0042221;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;metabolic process#GO:0008152;cellular response to peptide hormone stimulus#GO:0071375;localization#GO:0051179;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;macromolecule localization#GO:0033036;cellular response to nitrogen compound#GO:1901699;regulation of signal transduction#GO:0009966;regulation of response to stress#GO:0080134;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;intracellular protein localization#GO:0008104;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;secondary alcohol metabolic process#GO:1902652;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;cellular localization#GO:0051641;negative regulation of cell communication#GO:0010648;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;alcohol biosynthetic process#GO:0046165;cellular response to lipid#GO:0071396;cholesterol biosynthetic process#GO:0006695;negative regulation of signal transduction#GO:0009968;alcohol metabolic process#GO:0006066;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;lipid biosynthetic process#GO:0008610;negative regulation of response to stimulus#GO:0048585;response to peptide hormone#GO:0043434;SREBP signaling pathway#GO:0032933;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;cholesterol metabolic process#GO:0008203;cellular response to insulin stimulus#GO:0032869;secondary alcohol biosynthetic process#GO:1902653 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000016978.3|UniProtKB=F6ULX3 F6ULX3 STMN3 PTHR10104:SF17 STATHMIN STATHMIN-3 binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 neuron differentiation#GO:0030182;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;nervous system development#GO:0007399;microtubule depolymerization#GO:0007019;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;cellular component disassembly#GO:0022411;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular developmental process#GO:0048869;microtubule polymerization or depolymerization#GO:0031109;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;protein depolymerization#GO:0051261;multicellular organismal process#GO:0032501;regulation of microtubule-based process#GO:0032886;system development#GO:0048731;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;protein-containing complex disassembly#GO:0032984;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794 neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000015281.5|UniProtKB=A0A5F8G2T6 A0A5F8G2T6 FBRSL1 PTHR14429:SF20 FIBROSIN FAMILY MEMBER FIBROSIN-1-LIKE PROTEIN MONDO|Ensembl=ENSMODG00000007308.4|UniProtKB=F7EYB8 F7EYB8 PTHR24242:SF359 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11H6 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000049607.1|UniProtKB=A0A5F8GZJ4 A0A5F8GZJ4 ICAM3 PTHR13771:SF19 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 5 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cell adhesion#GO:0007155;leukocyte cell-cell adhesion#GO:0007159;cell adhesion mediated by integrin#GO:0033627;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000023138.2|UniProtKB=A0A5F8GJ61 A0A5F8GJ61 SSTR4 PTHR24229:SF35 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 4 peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;binding#GO:0005488;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089 cellular response to steroid hormone stimulus#GO:0071383;biological regulation#GO:0065007;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;cell communication#GO:0007154;response to steroid hormone#GO:0048545;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;response to endogenous stimulus#GO:0009719 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 MONDO|Ensembl=ENSMODG00000019816.2|UniProtKB=F6STG3 F6STG3 PTHR26453:SF148 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10A5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000026.4|UniProtKB=F6RF88 F6RF88 CLCA2 PTHR10579:SF66 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 2 monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;chloride channel activity#GO:0005254;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000016086.5|UniProtKB=F7FZ58 F7FZ58 PHC3 PTHR12247:SF88 POLYCOMB GROUP PROTEIN POLYHOMEOTIC-LIKE PROTEIN 3 binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393;protein binding#GO:0005515 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605 protein-containing complex#GO:0032991;PcG protein complex#GO:0031519;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000002210.3|UniProtKB=F7G3F2 F7G3F2 LYSET PTHR31925:SF1 TRANSMEMBRANE PROTEIN 251 LYSOSOMAL ENZYME TRAFFICKING FACTOR MONDO|Ensembl=ENSMODG00000015949.3|UniProtKB=F7G1W9 F7G1W9 FZD5 PTHR11309:SF136 FRIZZLED FRIZZLED-5 signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>Frizzled#P00475;Angiogenesis#P00005>Fzd#P00189;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428 MONDO|Ensembl=ENSMODG00000025204.3|UniProtKB=F7BG00 F7BG00 PTHR10281:SF121 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED VACUOLE MEMBRANE PROTEIN 1 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;intramembrane lipid carrier activity#GO:0140303 catabolic process#GO:0009056;cellular component organization#GO:0016043;Golgi organization#GO:0007030;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;macroautophagy#GO:0016236;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001173.3|UniProtKB=F7GHF2 F7GHF2 HSD17B7 PTHR44442:SF1 3-KETO-STEROID REDUCTASE 3-KETO-STEROID REDUCTASE_17-BETA-HYDROXYSTEROID DEHYDROGENASE 7 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 lipid biosynthetic process#GO:0008610;hormone metabolic process#GO:0042445;cholesterol biosynthetic process#GO:0006695;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;biological regulation#GO:0065007;steroid metabolic process#GO:0008202;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;secondary alcohol biosynthetic process#GO:1902653;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;small molecule metabolic process#GO:0044281;hormone biosynthetic process#GO:0042446;secondary alcohol metabolic process#GO:1902652;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;estrogen metabolic process#GO:0008210;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 reductase#PC00198;metabolite interconversion enzyme#PC00262 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 MONDO|Ensembl=ENSMODG00000028019.2|UniProtKB=K7E1F7 K7E1F7 LOC100617194 PTHR14003:SF33 TRANSCRIPTIONAL REPRESSOR PROTEIN YY TRANSCRIPTIONAL REPRESSOR PROTEIN YY1-LIKE double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell development#GO:0048468;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;PcG protein complex#GO:0031519;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000001020.4|UniProtKB=F6ZFF3 F6ZFF3 VWA3B PTHR46785:SF1 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B MONDO|Ensembl=ENSMODG00000004368.4|UniProtKB=F6W967 F6W967 TRNT1 PTHR46173:SF1 CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL RNA binding#GO:0003723;tRNA binding#GO:0000049;binding#GO:0005488;nucleic acid binding#GO:0003676 mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;mitochondrial RNA 3'-end processing#GO:0000965;tRNA 3'-end processing#GO:0042780;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000018181.4|UniProtKB=F7BTM3 F7BTM3 ZBTB20 PTHR24399:SF19 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 20 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014362.4|UniProtKB=A0A5F8GL42 A0A5F8GL42 ATRIP PTHR28594:SF1 ATR-INTERACTING PROTEIN ATR-INTERACTING PROTEIN macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000043417.1|UniProtKB=Q2ABA2 Q2ABA2 T2R3J PTHR11394:SF49 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 3 taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;transmembrane signaling receptor activity#GO:0004888 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011797.3|UniProtKB=F7CBS2 F7CBS2 GPR62 PTHR22752:SF11 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 62 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000018420.4|UniProtKB=F6XUV5 F6XUV5 ELOVL4 PTHR11157:SF126 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;transferase#PC00220 MONDO|Ensembl=ENSMODG00000040487.1|UniProtKB=K7E1M1 K7E1M1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007648.4|UniProtKB=F7FZH7 F7FZH7 PELI2 PTHR12098:SF5 E3 UBIQUITIN-PROTEIN LIGASE PELLINO-RELATED E3 UBIQUITIN-PROTEIN LIGASE PELLINO HOMOLOG 2 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000020734.4|UniProtKB=F7G8V5 F7G8V5 PTHR23400:SF0 DENTIN MATRIX ACIDIC PHOSPHOPROTEIN 1 DENTIN MATRIX ACIDIC PHOSPHOPROTEIN 1 binding#GO:0005488;extracellular matrix binding#GO:0050840 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000010083.4|UniProtKB=F6XMS8 F6XMS8 NMT2 PTHR11377:SF14 N-MYRISTOYL TRANSFERASE GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;localization within membrane#GO:0051668;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220 MONDO|Ensembl=ENSMODG00000027705.2|UniProtKB=K7DZ26 K7DZ26 SLC2A4RG PTHR13006:SF8 PAPILLOMAVIRUS REGULATORY FACTOR PRF-1 SLC2A4 REGULATOR transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000009620.4|UniProtKB=F6RFA7 F6RFA7 SMAD6 PTHR13703:SF28 SMAD SMAD FAMILY MEMBER 6 molecular function regulator activity#GO:0098772;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to growth factor stimulus#GO:0071363;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 TGF-beta signaling pathway#P00052>I-SMAD#G01548;TGF-beta signaling pathway#P00052>I-Smads#P01289 MONDO|Ensembl=ENSMODG00000011961.3|UniProtKB=F7CUZ4 F7CUZ4 SAMD1 PTHR36292:SF2 UPF0575 PROTEIN C19ORF67 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000005934.4|UniProtKB=F6WW80 F6WW80 TMEM63A PTHR13018:SF24 PROBABLE MEMBRANE PROTEIN DUF221-RELATED MECHANOSENSITIVE CATION CHANNEL TMEM63A gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion-gated channel activity#GO:0022839;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000015869.4|UniProtKB=A0A5F8G6K7 A0A5F8G6K7 DNAJC27 PTHR24073:SF269 DRAB5-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 27 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 G-protein#PC00020;small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 MONDO|Ensembl=ENSMODG00000042965.1|UniProtKB=A0A5F8GI47 A0A5F8GI47 MHC-I PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN peptide binding#GO:0042277;antigen binding#GO:0003823;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789 side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000009633.4|UniProtKB=F6QTZ2 F6QTZ2 TOMM22 PTHR12504:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 HOMOLOG mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000040332.1|UniProtKB=A0A5F8HAB3 A0A5F8HAB3 SYPL2 PTHR10306:SF8 SYNAPTOPHYSIN SYNAPTOPHYSIN-LIKE PROTEIN 2 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;cytoplasm#GO:0005737;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;presynapse#GO:0098793;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000010995.4|UniProtKB=F7DR31 F7DR31 SMAD4 PTHR13703:SF63 SMAD SMAD FAMILY MEMBER 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 cellular response to transforming growth factor beta stimulus#GO:0071560;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;response to transforming growth factor beta#GO:0071559;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;cellular response to growth factor stimulus#GO:0071363;transforming growth factor beta receptor signaling pathway#GO:0007179;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;intracellular signaling cassette#GO:0141124;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Wnt signaling pathway#P00057>Smad4#P01455;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>Co-Smads#P01276 MONDO|Ensembl=ENSMODG00000012011.4|UniProtKB=F7AMG8 F7AMG8 PTHR43895:SF39 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 MONDO|Ensembl=ENSMODG00000019962.2|UniProtKB=F6SRQ3 F6SRQ3 LOC100015106 PTHR48002:SF128 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C6 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000047638.1|UniProtKB=A0A5F8GYX6 A0A5F8GYX6 PTHR12002:SF3 CLAUDIN CLAUDIN-23 cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular process#GO:0009987;cell junction organization#GO:0034330;cellular component assembly#GO:0022607 tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;apical junction complex#GO:0043296;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000038694.1|UniProtKB=A0A5F8HG62 A0A5F8HG62 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000025470.2|UniProtKB=A0A5F8H904 A0A5F8H904 SNAPC5 PTHR15333:SF2 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 5 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 5 MONDO|Ensembl=ENSMODG00000010734.3|UniProtKB=F7G7F7 F7G7F7 PTHR14715:SF4 FAM124 DOMAIN-CONTAINING PROTEIN-RELATED PROTEIN FAM124A MONDO|Ensembl=ENSMODG00000005330.4|UniProtKB=F7D206 F7D206 RNF167 PTHR22765:SF35 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF167 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;biological regulation#GO:0065007;lysosome localization#GO:0032418;cellular process#GO:0009987;protein metabolic process#GO:0019538;localization#GO:0051179;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;organelle localization#GO:0051640;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000004486.3|UniProtKB=F6VR58 F6VR58 MPV17L PTHR11266:SF39 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MPV17-LIKE PROTEIN negative regulation of programmed cell death#GO:0043069;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;regulation of mitochondrial membrane permeability#GO:0046902;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of membrane permeability#GO:0090559;negative regulation of apoptotic process#GO:0043066;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of organelle organization#GO:0033043;regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;regulation of biological quality#GO:0065008;negative regulation of cell communication#GO:0010648 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 transporter#PC00227 MONDO|Ensembl=ENSMODG00000017788.5|UniProtKB=A0A5F8GQ04 A0A5F8GQ04 PPIP5K1 PTHR12750:SF11 DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 nucleotide kinase#PC00172;kinase#PC00137 MONDO|Ensembl=ENSMODG00000009960.4|UniProtKB=F6Y8J3 F6Y8J3 PTER PTHR10819:SF3 PHOSPHOTRIESTERASE-RELATED N-ACETYLTAURINE HYDROLASE esterase#PC00097;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000039155.1|UniProtKB=F7EAU9 F7EAU9 PTHR26453:SF33 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000869.3|UniProtKB=F7AVL1 F7AVL1 TRBV30 PTHR23268:SF31 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 30 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000040906.1|UniProtKB=A0A5F8GXR2 A0A5F8GXR2 CXCR4 PTHR10489:SF594 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 4 protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 regulation of biological process#GO:0050789;signaling#GO:0023052;central nervous system development#GO:0007417;response to stimulus#GO:0050896;cell differentiation#GO:0030154;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;signal transduction#GO:0007165;cellular process#GO:0009987;head development#GO:0060322;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;response to chemical#GO:0042221;taxis#GO:0042330;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cell motility#GO:0048870;chemotaxis#GO:0006935;system development#GO:0048731;cell chemotaxis#GO:0060326;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;anatomical structure development#GO:0048856;immune response#GO:0006955;biological regulation#GO:0065007;brain development#GO:0007420;cell migration#GO:0016477;multicellular organismal process#GO:0032501;developmental process#GO:0032502;response to external stimulus#GO:0009605;neurogenesis#GO:0022008;calcium-mediated signaling#GO:0019722;cellular developmental process#GO:0048869 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854;Axon guidance mediated by Slit/Robo#P00008>Cxcr4#P00351 MONDO|Ensembl=ENSMODG00000051022.1|UniProtKB=K7E5W9 K7E5W9 LOC103105830 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED RETROVIRAL ENVELOPE PROTEIN GP41-LIKE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001251.5|UniProtKB=F7CJ78 F7CJ78 DMRTA2 PTHR12322:SF76 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR A2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 sex differentiation#GO:0007548;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000012600.4|UniProtKB=F6PI76 F6PI76 GFI1B PTHR24393:SF146 ZINC FINGER PROTEIN ZINC FINGER PROTEIN GFI-1B DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal process#GO:0051239;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell development#GO:0060284;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of hemopoiesis#GO:1903706;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000008108.4|UniProtKB=F7G5T9 F7G5T9 NTN4 PTHR10574:SF282 NETRIN/LAMININ-RELATED NETRIN-4 neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;generation of neurons#GO:0048699;cell adhesion#GO:0007155;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;substrate adhesion-dependent cell spreading#GO:0034446;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component assembly#GO:0022607;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;system development#GO:0048731;external encapsulating structure organization#GO:0045229;cell motility#GO:0048870;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cell migration#GO:0016477;extracellular matrix assembly#GO:0085029;multicellular organismal process#GO:0032501;tissue development#GO:0009888;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411 basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 extracellular matrix protein#PC00102 Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344;Axon guidance mediated by netrin#P00009>Netrin#P00357;Integrin signalling pathway#P00034>Laminin#P00947 MONDO|Ensembl=ENSMODG00000003162.3|UniProtKB=F6WDK8 F6WDK8 PTHR18945:SF764 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3E transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 transport#GO:0006810;establishment of localization#GO:0051234;synaptic transmission, cholinergic#GO:0007271;cellular response to nitrogen compound#GO:1901699;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;trans-synaptic signaling#GO:0099537;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;response to nitrogen compound#GO:1901698;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000015562.4|UniProtKB=F7AJ83 F7AJ83 PECR PTHR24317:SF7 PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;terpenoid metabolic process#GO:0006721;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;diterpenoid metabolic process#GO:0016101;isoprenoid metabolic process#GO:0006720 peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000043418.1|UniProtKB=A0A5F8GXQ9 A0A5F8GXQ9 PTHR28604:SF1 FAMILY NOT NAMED PROLINE-RICH PROTEIN 29 MONDO|Ensembl=ENSMODG00000007925.4|UniProtKB=F7GIA4 F7GIA4 SIGMAR1 PTHR10868:SF4 SIGMA 1-TYPE OPIOID RECEPTOR-RELATED SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of programmed cell death#GO:0043067;regulation of neuron apoptotic process#GO:0043523;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of cellular response to stress#GO:0080135 cell junction#GO:0030054;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007327.4|UniProtKB=F7EF09 F7EF09 WNT7B PTHR12027:SF73 WNT RELATED PROTEIN WNT-7B signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125 system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;cell fate commitment#GO:0045165;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;positive regulation of JNK cascade#GO:0046330;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of JNK cascade#GO:0046328;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444;Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206 MONDO|Ensembl=ENSMODG00000023830.1|UniProtKB=F6U994 F6U994 LOC100023386 PTHR26451:SF52 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 12D2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000042532.1|UniProtKB=A0A5F8GUN0 A0A5F8GUN0 PTHR14132:SF11 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 3 ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transmembrane transport#GO:0034765;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of transmembrane transport#GO:0034762;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic cation transmembrane transport#GO:1904062 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000025328.2|UniProtKB=F6X4V0 F6X4V0 BHMT PTHR46120:SF1 BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE 1 BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 proteinogenic amino acid biosynthetic process#GO:0170038;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;aspartate family amino acid biosynthetic process#GO:0009067 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000015460.4|UniProtKB=F6S3L6 F6S3L6 KDM8 PTHR12461:SF106 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED BIFUNCTIONAL PEPTIDASE AND ARGINYL-HYDROXYLASE JMJD5 binding#GO:0005488;chromatin binding#GO:0003682;dioxygenase activity#GO:0051213;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;protein demethylase activity#GO:0140457 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000037498.1|UniProtKB=A0A5F8GWK9 A0A5F8GWK9 TMSB10 PTHR12021:SF10 THYMOSIN BETA THYMOSIN BETA-10 protein binding#GO:0005515;actin monomer binding#GO:0003785;cytoskeletal protein binding#GO:0008092;protein sequestering activity#GO:0140311;actin binding#GO:0003779;binding#GO:0005488;molecular sequestering activity#GO:0140313 regulation of cell motility#GO:2000145;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000040460.1|UniProtKB=A0A5F8G392 A0A5F8G392 SERTAD4 PTHR14272:SF4 SERTA DOMAIN-CONTAINING PROTEIN 4 SERTA DOMAIN-CONTAINING PROTEIN 4 MONDO|Ensembl=ENSMODG00000021198.4|UniProtKB=F6XE46 F6XE46 AP1S3 PTHR11753:SF18 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-1 COMPLEX SUBUNIT SIGMA-3 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000017722.4|UniProtKB=F7FHD1 F7FHD1 MAPK1 PTHR24055:SF584 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Parkinson disease#P00049>ERK#P01211;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Apoptosis signaling pathway#P00006>MAPK#P00269;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;Endothelin signaling pathway#P00019>ERK#P00566;Ras Pathway#P04393>ERK#P04542;T cell activation#P00053>ERK#P01300;PDGF signaling pathway#P00047>ERK#P01143;Angiogenesis#P00005>MEK#P00225;CCKR signaling map#P06959>MAPK1/3#P07228;Integrin signalling pathway#P00034>ERK#P00907;Interleukin signaling pathway#P00036>ERK#P00965;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>MAPK#P05937;B cell activation#P00010>ERK#P00371;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;CCKR signaling map#P06959>MAPK1#P07166;VEGF signaling pathway#P00056>MEK#P01402;FGF signaling pathway#P00021>ERK1-2#P00627;EGF receptor signaling pathway#P00018>ERK1-2#P00543;Angiogenesis#P00005>Erk#P00203;Toll receptor signaling pathway#P00054>ERK2#P01356;Gonadotropin-releasing hormone receptor pathway#P06664>ERK1/2#P06786;VEGF signaling pathway#P00056>Erk#P01407 MONDO|Ensembl=ENSMODG00000000626.4|UniProtKB=F6TAH0 F6TAH0 PLCG1 PTHR10336:SF173 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-1 glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;hydrolase activity#GO:0016787 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;calcium ion transmembrane transport#GO:0070588;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;metabolic process#GO:0008152;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;monoatomic cation transmembrane transport#GO:0098655;regulation of multicellular organismal process#GO:0051239;glycerophospholipid metabolic process#GO:0006650;intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;regulation of cell migration#GO:0030334;lipid metabolic process#GO:0006629;transport#GO:0006810;phosphatidylinositol metabolic process#GO:0046488;positive regulation of locomotion#GO:0040017;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;monoatomic ion transmembrane transport#GO:0034220 ruffle#GO:0001726;cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;ruffle membrane#GO:0032587;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252 hydrolase#PC00121;phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143 5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;PDGF signaling pathway#P00047>PLCgamma#P01171;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;EGF receptor signaling pathway#P00018>PLCgamma#P00556;Axon guidance mediated by netrin#P00009>Phospholipase C#P00362;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;FGF signaling pathway#P00021>PLCgamma#P00638;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Angiogenesis#P00005>PLC-gamma#P00256;CCKR signaling map#P06959>PLCgamma1#P07037;T cell activation#P00053>PLC-gamma#P01320;VEGF signaling pathway#P00056>PLC-gamma#P01414 MONDO|Ensembl=ENSMODG00000015441.3|UniProtKB=F6S4K6 F6S4K6 PANK2 PTHR12280:SF25 PANTOTHENATE KINASE PANTOTHENATE KINASE 2, MITOCHONDRIAL phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 MONDO|Ensembl=ENSMODG00000011702.3|UniProtKB=F7G3R0 F7G3R0 SKIC8 PTHR44090:SF1 WD REPEAT-CONTAINING PROTEIN 61 SUPERKILLER COMPLEX PROTEIN 8 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695 MONDO|Ensembl=ENSMODG00000000699.4|UniProtKB=F6WLR5 F6WLR5 AP4B1 PTHR11134:SF4 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-4 COMPLEX SUBUNIT BETA-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;coated membrane#GO:0048475;membrane coat#GO:0030117;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;AP-type membrane coat adaptor complex#GO:0030119;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000018894.4|UniProtKB=F7CQT2 F7CQT2 CYP39A1 PTHR24304:SF2 CYTOCHROME P450 FAMILY 7 24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000013554.4|UniProtKB=F7C3D4 F7C3D4 KRT12 PTHR23239:SF369 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 12 structural molecule activity#GO:0005198 developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009;organelle organization#GO:0006996;cellular process#GO:0009987;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104 intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000051113.1|UniProtKB=A0A5F8H236 A0A5F8H236 PTHR46479:SF1 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lysosome localization#GO:0032418;vesicle-mediated transport#GO:0016192;organelle localization#GO:0051640;intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;BLOC-1 complex#GO:0031083;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000000483.5|UniProtKB=F6UA74 F6UA74 HOXA5 PTHR45659:SF10 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-A5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;anterior/posterior pattern specification#GO:0009952;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000000822.4|UniProtKB=F6S9A6 F6S9A6 SRBD1 PTHR10724:SF10 30S RIBOSOMAL PROTEIN S1 S1 RNA-BINDING DOMAIN-CONTAINING PROTEIN 1 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000047840.1|UniProtKB=A0A5F8H704 A0A5F8H704 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007843.3|UniProtKB=F7ET99 F7ET99 PHF24 PTHR10891:SF1022 EF-HAND CALCIUM-BINDING DOMAIN CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000017944.4|UniProtKB=F7E3F5 F7E3F5 MGP PTHR10109:SF0 MATRIX GLA PROTEIN MATRIX GLA PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 MONDO|Ensembl=ENSMODG00000007036.4|UniProtKB=A0A5F8GKJ9 A0A5F8GKJ9 TNFSF12 PTHR15151:SF20 PROTEIN EIGER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 12 cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 immune system process#GO:0002376;cell communication#GO:0007154;cell death#GO:0008219;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;signaling#GO:0023052;regulation of cellular process#GO:0050794;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;apoptotic signaling pathway#GO:0097190;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000046916.1|UniProtKB=A0A5F8HBG4 A0A5F8HBG4 PTHR23304:SF189 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000044606.1|UniProtKB=A0A5F8G7D5 A0A5F8G7D5 GOLPH3 PTHR12704:SF3 TRANS-GOLGI PROTEIN GMX33 GOLGI PHOSPHOPROTEIN 3 cargo adaptor activity#GO:0140312;lipid binding#GO:0008289;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001;cellular component organization#GO:0016043;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;Golgi organization#GO:0007030 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000042102.1|UniProtKB=A0A5F8HB01 A0A5F8HB01 LOC130456287 PTHR14256:SF3 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT CYTOCHROME C OXIDASE ASSOCIATED SUBUNIT FA4L3 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000001218.3|UniProtKB=F7G7R1 F7G7R1 PTHR28638:SF2 CELL CYCLE PROGRESSION PROTEIN 1 CELL CYCLE PROGRESSION PROTEIN 1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000007165.4|UniProtKB=A0A5F8GLV5 A0A5F8GLV5 SLIT3 PTHR45836:SF9 SLIT HOMOLOG SLIT HOMOLOG 3 PROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367;heparin binding#GO:0008201 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;neuron projection development#GO:0031175;cellular process#GO:0009987;taxis#GO:0042330;response to chemical#GO:0042221;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;locomotion#GO:0040011;chemotaxis#GO:0006935;anatomical structure development#GO:0048856;system development#GO:0048731;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485 Axon guidance mediated by Slit/Robo#P00008>Slit#P00342 MONDO|Ensembl=ENSMODG00000007881.5|UniProtKB=F6ZH57 F6ZH57 ARID4A PTHR13964:SF26 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 4A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000023714.1|UniProtKB=F6QQI6 F6QQI6 FKRP PTHR13627:SF31 FUKUTIN RELATED PROTEIN RIBITOL 5-PHOSPHATE TRANSFERASE FKRP phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;protein O-linked glycosylation via mannose#GO:0035269;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 MONDO|Ensembl=ENSMODG00000010603.3|UniProtKB=F7G897 F7G897 RELL2 PTHR31481:SF0 RELT-LIKE PROTEIN 2 RELL2 RELT-LIKE PROTEIN 2 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;positive regulation of cell-substrate adhesion#GO:0010811;positive regulation of cell adhesion#GO:0045785;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584 MONDO|Ensembl=ENSMODG00000023656.2|UniProtKB=F7GA43 F7GA43 PTHR33426:SF30 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000004312.4|UniProtKB=A0A5F8G724 A0A5F8G724 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023 cell communication#GO:0007154;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000018342.4|UniProtKB=F6PR86 F6PR86 TULP3 PTHR16517:SF138 TUBBY-RELATED TUBBY-RELATED PROTEIN 3 localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;protein localization to cilium#GO:0061512;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000012768.3|UniProtKB=F6SIN4 F6SIN4 LOC130458969 PTHR26453:SF238 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10N1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007995.5|UniProtKB=F7D594 F7D594 MPHOSPH8 PTHR24184:SF28 SI:CH211-189E2.2 ANKYRIN REPEAT AND SOCS BOX CONTAINING 3 cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000039790.1|UniProtKB=F7CIV5 F7CIV5 VPS28 PTHR12937:SF0 VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;macromolecule localization#GO:0033036;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;protein localization to vacuole#GO:0072665;protein metabolic process#GO:0019538;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;endosomal transport#GO:0016197;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;establishment of protein localization to vacuole#GO:0072666;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein transport#GO:0015031;cellular localization#GO:0051641 cytosol#GO:0005829;vesicle membrane#GO:0012506;membrane#GO:0016020;ESCRT I complex#GO:0000813;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000049711.1|UniProtKB=M9MMI4 M9MMI4 PTHR44427:SF13 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 4-RELATED cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000002502.5|UniProtKB=F7ACN8 F7ACN8 COPS7B PTHR15350:SF8 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 COP9 SIGNALOSOME COMPLEX SUBUNIT 7B primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000001694.4|UniProtKB=F6S7Q0 F6S7Q0 CTSO PTHR12411:SF992 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN O catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000021067.4|UniProtKB=F6V1Y4 F6V1Y4 IFNAR1 PTHR20859:SF54 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON ALPHA_BETA RECEPTOR 1 molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to other organism#GO:0051707;biological regulation#GO:0065007;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;defense response to symbiont#GO:0140546;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cell communication#GO:0007154;response to peptide#GO:1901652;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;cytokine-mediated signaling pathway#GO:0019221 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cytokine receptor#P00866 MONDO|Ensembl=ENSMODG00000023586.3|UniProtKB=F7BPJ1 F7BPJ1 LOC103103403 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000024535.3|UniProtKB=F7F5R2 F7F5R2 KCND2 PTHR11537:SF265 VOLTAGE-GATED POTASSIUM CHANNEL A-TYPE VOLTAGE-GATED POTASSIUM CHANNEL KCND2 transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;metal ion transport#GO:0030001;action potential#GO:0001508;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008 cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;dendritic tree#GO:0097447;transmembrane transporter complex#GO:1902495;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cell body#GO:0044297;plasma membrane protein complex#GO:0098797;dendritic spine#GO:0043197;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuronal cell body#GO:0043025;cell projection#GO:0042995;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000038247.1|UniProtKB=F6Q031 F6Q031 LOC100022225 PTHR26450:SF164 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51B2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009234.3|UniProtKB=F7EE24 F7EE24 SPSB1 PTHR12245:SF8 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 1 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000049178.1|UniProtKB=A0A5F8GAA6 A0A5F8GAA6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000008346.4|UniProtKB=F7EKQ1 F7EKQ1 CDC42EP3 PTHR15344:SF3 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 3 binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;protein binding#GO:0005515 regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;small GTPase-mediated signal transduction#GO:0007264;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;positive regulation of cell projection organization#GO:0031346;regulation of cell projection assembly#GO:0060491;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of supramolecular fiber organization#GO:1902903;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of anatomical structure size#GO:0090066;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of actin cytoskeleton organization#GO:0032956;intracellular signaling cassette#GO:0141124;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;Rho protein signal transduction#GO:0007266;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of plasma membrane bounded cell projection assembly#GO:0120032 cell periphery#GO:0071944;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004804.3|UniProtKB=F6V6A1 F6V6A1 PTHR11158:SF29 MSF1/PX19 RELATED PRELI DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013 macromolecule localization#GO:0033036;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;phospholipid transport#GO:0015914;lipid localization#GO:0010876;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000016163.4|UniProtKB=F7CMD1 F7CMD1 TMEM204 PTHR14627:SF0 TRANSMEMBRANE PROTEIN 204 TRANSMEMBRANE PROTEIN 204 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000013130.4|UniProtKB=F7B062 F7B062 KCNK6 PTHR11003:SF28 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 6 potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000004715.4|UniProtKB=F6QGW7 F6QGW7 THUMPD3 PTHR14911:SF13 THUMP DOMAIN-CONTAINING TRNA (GUANINE(6)-N(2))-METHYLTRANSFERASE THUMP3 tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000042255.1|UniProtKB=F6Q3N8 F6Q3N8 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000047769.1|UniProtKB=F7C9R4 F7C9R4 PTHR24404:SF96 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420-LIKE transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000013566.3|UniProtKB=F7BIF2 F7BIF2 PTHR48617:SF1 FAMILY NOT NAMED SS18-LIKE PROTEIN 2 MONDO|Ensembl=ENSMODG00000017646.4|UniProtKB=F6YKK1 F6YKK1 MFSD2A PTHR11328:SF29 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN SODIUM-DEPENDENT LYSOPHOSPHATIDYLCHOLINE SYMPORTER 1 carbohydrate derivative transmembrane transporter activity#GO:1901505;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;organophosphate ester transmembrane transporter activity#GO:0015605;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;monocarboxylic acid transmembrane transporter activity#GO:0008028;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 circulatory system process#GO:0003013;lipid localization#GO:0010876;transmembrane transport#GO:0055085;fatty acid transport#GO:0015908;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;carbohydrate derivative transport#GO:1901264;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;system process#GO:0003008;macromolecule localization#GO:0033036;cellular process#GO:0009987;multicellular organismal process#GO:0032501;lipid transport#GO:0006869;phospholipid transport#GO:0015914;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid translocation#GO:0045332 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000002168.3|UniProtKB=F6YEF0 F6YEF0 PTHR16275:SF9 COILED-COIL DOMAIN-CONTAINING PROTEIN 40 COILED-COIL DOMAIN-CONTAINING PROTEIN 40 organelle assembly#GO:0070925;embryonic organ development#GO:0048568;microtubule bundle formation#GO:0001578;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;tissue morphogenesis#GO:0048729;localization#GO:0051179;system development#GO:0048731;axoneme assembly#GO:0035082;tube morphogenesis#GO:0035239;heart morphogenesis#GO:0003007;determination of left/right symmetry#GO:0007368;animal organ morphogenesis#GO:0009887;microtubule-based movement#GO:0007018;specification of symmetry#GO:0009799;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;regionalization#GO:0003002;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelium development#GO:0060429;tube development#GO:0035295;plasma membrane bounded cell projection organization#GO:0120036;animal gross anatomical part developmental process#GO:0160108;microtubule-based transport#GO:0099111;cilium movement#GO:0003341;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;circulatory system development#GO:0072359;cell projection organization#GO:0030030;left/right pattern formation#GO:0060972;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;morphogenesis of an epithelium#GO:0002009;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;heart development#GO:0007507;cellular component assembly#GO:0022607;embryo development#GO:0009790;determination of bilateral symmetry#GO:0009855;cytoskeleton organization#GO:0007010 plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000012034.4|UniProtKB=F7ALQ2 F7ALQ2 LSM14A PTHR13586:SF2 SCD6 PROTEIN-RELATED PROTEIN LSM14 HOMOLOG A RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 cellular component assembly#GO:0022607;cytoplasmic stress granule assembly#GO:0034063;P-body assembly#GO:0033962;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925 intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000046352.1|UniProtKB=K7E477 K7E477 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000017162.4|UniProtKB=F6QDN1 F6QDN1 TXLNG PTHR16127:SF14 TAXILIN GAMMA-TAXILIN regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000038185.1|UniProtKB=A0A5F8H926 A0A5F8H926 C2H6orf15 PTHR15817:SF2 STG PROTEIN SIMILAR TO HUMAN CHROMOSOME 6 OPEN READING FRAME 15 MONDO|Ensembl=ENSMODG00000019895.4|UniProtKB=F6W5U6 F6W5U6 ZNF408 PTHR24409:SF450 ZINC FINGER PROTEIN 142 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 17 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004896.3|UniProtKB=F7C2C6 F7C2C6 PTHR24055:SF171 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 6 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 VEGF signaling pathway#P00056>MEK#P01402;PDGF signaling pathway#P00047>ERK#P01143;Angiogenesis#P00005>MEK#P00225;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Interleukin signaling pathway#P00036>ERK#P00965;Integrin signalling pathway#P00034>ERK#P00907 MONDO|Ensembl=ENSMODG00000042945.1|UniProtKB=A0A5F8GM25 A0A5F8GM25 GPN2 PTHR21231:SF3 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 2 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;protein-binding activity modulator#PC00095;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000021451.4|UniProtKB=A0A5F8GYK5 A0A5F8GYK5 MTCL1 PTHR15742:SF3 GIRDIN MICROTUBULE CROSS-LINKING FACTOR 1 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;establishment or maintenance of bipolar cell polarity#GO:0061245;microtubule bundle formation#GO:0001578;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment or maintenance of cell polarity#GO:0007163;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;cellular component organization or biogenesis#GO:0071840 spindle pole#GO:0000922;midbody#GO:0030496;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;plasma membrane region#GO:0098590;supramolecular polymer#GO:0099081;spindle#GO:0005819;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 MONDO|Ensembl=ENSMODG00000007103.4|UniProtKB=F6Q8G8 F6Q8G8 PCNX1 PTHR12372:SF2 PECANEX PECANEX-LIKE PROTEIN 1 MONDO|Ensembl=ENSMODG00000002925.4|UniProtKB=F6PMJ2 F6PMJ2 SDR39U1 PTHR11092:SF0 SUGAR NUCLEOTIDE EPIMERASE RELATED EPIMERASE FAMILY PROTEIN SDR39U1 epimerase/racemase#PC00096 MONDO|Ensembl=ENSMODG00000008141.4|UniProtKB=F7G1L4 F7G1L4 MAF PTHR10129:SF9 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAF sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 animal gross anatomical part developmental process#GO:0160108;eye development#GO:0001654;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;lens development in camera-type eye#GO:0002088;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular process#GO:0009987;sensory system development#GO:0048880;camera-type eye development#GO:0043010;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;visual system development#GO:0150063;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 MONDO|Ensembl=ENSMODG00000027362.2|UniProtKB=K7E1E1 K7E1E1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000041516.1|UniProtKB=A0A5F8GTS4 A0A5F8GTS4 PTHR31294:SF8 FAMILY NOT NAMED DUF4657 DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000046087.1|UniProtKB=K7E644 K7E644 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001398.4|UniProtKB=A0A5F8GAT4 A0A5F8GAT4 RFX2 PTHR12619:SF17 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;male gamete generation#GO:0048232;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;spermatogenesis#GO:0007283;plasma membrane bounded cell projection assembly#GO:0120031;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;regulation of RNA metabolic process#GO:0051252;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;sexual reproduction#GO:0019953;spermatid development#GO:0007286;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell differentiation#GO:0030154;gamete generation#GO:0007276;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;spermatid differentiation#GO:0048515 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000017471.3|UniProtKB=F7FF58 F7FF58 PTHR11430:SF124 LIPOCALIN LIPOCALIN 1-LIKE PROTEIN 1-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000028879.2|UniProtKB=K7E4T7 K7E4T7 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000040747.1|UniProtKB=A0A5F8H3M9 A0A5F8H3M9 OARD1 PTHR12521:SF0 PROTEIN C6ORF130 ADP-RIBOSE GLYCOHYDROLASE OARD1 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 purine nucleoside metabolic process#GO:0042278;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;cellular response to stimulus#GO:0051716;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000007665.4|UniProtKB=F7FNQ9 F7FNQ9 TEKT3 PTHR19960:SF24 TEKTIN TEKTIN-3 cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;organelle assembly#GO:0070925;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000004807.4|UniProtKB=A0A5F8GMR9 A0A5F8GMR9 DROSHA PTHR11207:SF37 RIBONUCLEASE III RIBONUCLEASE 3 nuclease activity#GO:0004518;RNA binding#GO:0003723;hydrolase activity#GO:0016787;double-stranded RNA binding#GO:0003725;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;primary miRNA processing#GO:0031053;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;pre-miRNA processing#GO:0031054;regulation of macromolecule metabolic process#GO:0060255 endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 endoribonuclease#PC00094;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000000188.4|UniProtKB=A0A5F8GC58 A0A5F8GC58 CFAP70 PTHR44314:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;organelle assembly#GO:0070925;cilium movement#GO:0003341 cilium#GO:0005929;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000002926.4|UniProtKB=H9H617 H9H617 EMD PTHR15171:SF2 EMERIN EMERIN binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 membraneless organelle#GO:0043228;nuclear inner membrane#GO:0005637;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;spindle#GO:0005819;cytoskeleton#GO:0005856;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;nucleus#GO:0005634;organelle inner membrane#GO:0019866;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967 MONDO|Ensembl=ENSMODG00000001508.3|UniProtKB=F7F4E8 F7F4E8 PTHR24024:SF13 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A PULMONARY SURFACTANT-ASSOCIATED PROTEIN A1 pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 positive regulation of cellular component organization#GO:0051130;immune system process#GO:0002376;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of endocytosis#GO:0030100;immune effector process#GO:0002252;humoral immune response#GO:0006959;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;defense response to symbiont#GO:0140546;positive regulation of transport#GO:0051050;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;defense response to other organism#GO:0098542;regulation of immune response#GO:0050776;response to external biotic stimulus#GO:0043207;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;complement activation#GO:0006956;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;positive regulation of endocytosis#GO:0045807 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211;surfactant#PC00212 MONDO|Ensembl=ENSMODG00000002254.4|UniProtKB=A0A5F8GUQ2 A0A5F8GUQ2 SLC26A11 PTHR11814:SF282 SULFATE TRANSPORTER SODIUM-INDEPENDENT SULFATE ANION TRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000015864.4|UniProtKB=A0A5F8G1U1 A0A5F8G1U1 LOC100020912 PTHR23024:SF222 ARYLACETAMIDE DEACETYLASE ARYLACETAMIDE DEACETYLASE serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;lipase activity#GO:0016298 catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;neutral lipid metabolic process#GO:0006638;acylglycerol catabolic process#GO:0046464;metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;acylglycerol metabolic process#GO:0006639;neutral lipid catabolic process#GO:0046461;lipid metabolic process#GO:0006629 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 deacetylase#PC00087 MONDO|Ensembl=ENSMODG00000010632.4|UniProtKB=F7D550 F7D550 SCD PTHR11351:SF102 ACYL-COA DESATURASE STEAROYL-COA DESATURASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;unsaturated fatty acid biosynthetic process#GO:0006636;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;oxoacid metabolic process#GO:0043436 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 MONDO|Ensembl=ENSMODG00000000997.4|UniProtKB=A0A5F8GXL7 A0A5F8GXL7 PTHR14167:SF48 SH3 DOMAIN-CONTAINING SH3 DOMAIN-CONTAINING PROTEIN 19 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020969.3|UniProtKB=A0A5F8H1T8 A0A5F8H1T8 SH3BGR PTHR12232:SF1 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 MONDO|Ensembl=ENSMODG00000050379.1|UniProtKB=A0A5F8HCX8 A0A5F8HCX8 BTBD1 PTHR45774:SF1 BTB/POZ DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN 1 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;neurogenesis#GO:0022008;system development#GO:0048731;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000042710.1|UniProtKB=A0A5F8GN76 A0A5F8GN76 VN2R555 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000017662.4|UniProtKB=F6YJW0 F6YJW0 HIC2 PTHR24394:SF22 ZINC FINGER PROTEIN HYPERMETHYLATED IN CANCER 2 PROTEIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006877.4|UniProtKB=F6PWE4 F6PWE4 EXO1 PTHR11081:SF8 FLAP ENDONUCLEASE FAMILY MEMBER EXONUCLEASE 1 hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 MONDO|Ensembl=ENSMODG00000038740.1|UniProtKB=A0A5F8HGG6 A0A5F8HGG6 LOC103103519 PTHR46804:SF4 ADP RIBOSYLATION FACTOR LIKE GTPASE 14 EFFECTOR PROTEIN LIKE ARL14 EFFECTOR PROTEIN-LIKE G-protein#PC00020;protein-binding activity modulator#PC00095;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000009336.4|UniProtKB=F7GAZ5 F7GAZ5 GPR180 PTHR23252:SF29 INTIMAL THICKNESS RECEPTOR-RELATED INTEGRAL MEMBRANE PROTEIN GPR180 MONDO|Ensembl=ENSMODG00000007606.4|UniProtKB=F7C5S5 F7C5S5 LOC100028308 PTHR24092:SF52 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE FETA lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;intramembrane lipid carrier activity#GO:0140303 localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;lipid transport#GO:0006869;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;membrane organization#GO:0061024;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000005037.4|UniProtKB=F7E992 F7E992 PTHR23036:SF101 CYTOKINE RECEPTOR INTERLEUKIN-13 RECEPTOR SUBUNIT ALPHA-2 cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515 response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 MONDO|Ensembl=ENSMODG00000016420.3|UniProtKB=F7ASW0 F7ASW0 CLUAP1 PTHR21547:SF0 CLUSTERIN ASSOCIATED PROTEIN 1 CLUSTERIN-ASSOCIATED PROTEIN 1 cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intraciliary transport particle B#GO:0030992;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000037058.1|UniProtKB=A0A5F8HI68 A0A5F8HI68 YAE1 PTHR18829:SF0 PROTEIN YAE1 HOMOLOG PROTEIN YAE1 HOMOLOG MONDO|Ensembl=ENSMODG00000014938.4|UniProtKB=A0A5F8GM28 A0A5F8GM28 CHERP PTHR12323:SF0 SR-RELATED CTD ASSOCIATED FACTOR 6 CALCIUM HOMEOSTASIS ENDOPLASMIC RETICULUM PROTEIN calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000019296.4|UniProtKB=F6RZ81 F6RZ81 NUP54 PTHR13000:SF0 NUCLEOPORIN P54 NUCLEOPORIN P54 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;localization within membrane#GO:0051668;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear pore organization#GO:0006999;nuclear transport#GO:0051169;cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;organelle organization#GO:0006996;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein-containing complex organization#GO:0043933;intracellular protein localization#GO:0008104;nucleus organization#GO:0006997;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513 transporter#PC00227 MONDO|Ensembl=ENSMODG00000043342.1|UniProtKB=A0A5F8H4I7 A0A5F8H4I7 SRD5A2 PTHR10556:SF37 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;development of primary male sexual characteristics#GO:0046546;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;lipid metabolic process#GO:0006629;male sex differentiation#GO:0046661;multicellular organism development#GO:0007275;steroid biosynthetic process#GO:0006694;animal organ development#GO:0048513;male gonad development#GO:0008584;sex differentiation#GO:0007548;cellular process#GO:0009987;hormone metabolic process#GO:0042445;lipid biosynthetic process#GO:0008610;multicellular organismal process#GO:0032501;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;biological regulation#GO:0065007;gonad development#GO:0008406;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;system development#GO:0048731;reproductive system development#GO:0061458;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;regulation of hormone levels#GO:0010817;hormone biosynthetic process#GO:0042446;reproductive process#GO:0022414;reproductive structure development#GO:0048608 cell body#GO:0044297;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000024334.2|UniProtKB=F7DG85 F7DG85 PTHR26454:SF10 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6V1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012910.4|UniProtKB=F7GKP1 F7GKP1 PTHR47966:SF72 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED GASTRICSIN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;aspartic protease#PC00053 MONDO|Ensembl=ENSMODG00000037708.1|UniProtKB=K7DZ43 K7DZ43 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000014339.4|UniProtKB=K7E5T8 K7E5T8 VMP1 PTHR10281:SF121 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED VACUOLE MEMBRANE PROTEIN 1 intramembrane lipid carrier activity#GO:0140303;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;macroautophagy#GO:0016236;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;organelle assembly#GO:0070925;catabolic process#GO:0009056;cellular component organization#GO:0016043;Golgi organization#GO:0007030 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019412.3|UniProtKB=H9H7D0 H9H7D0 PTHR45706:SF3 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 21 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000010124.5|UniProtKB=F6WNK8 F6WNK8 TCERG1 PTHR15377:SF7 TRANSCRIPTION ELONGATION REGULATOR 1 TRANSCRIPTION ELONGATION REGULATOR 1 protein binding#GO:0005515;RNA polymerase binding#GO:0070063;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;transcription coregulator activity#GO:0003712;binding#GO:0005488 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000008900.4|UniProtKB=F7B4C1 F7B4C1 GRIA1 PTHR18966:SF157 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 1 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836 regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;synaptic signaling#GO:0099536;cellular process#GO:0009987;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051 protein-containing complex#GO:0032991;neuron projection#GO:0043005;transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;neuron spine#GO:0044309;cell projection#GO:0042995;postsynapse#GO:0098794;dendritic spine#GO:0043197;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;dendrite#GO:0030425;postsynaptic density#GO:0014069;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu1#P01018;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 MONDO|Ensembl=ENSMODG00000048047.1|UniProtKB=A0A5F8H1W2 A0A5F8H1W2 PTHR24381:SF478 ZINC FINGER PROTEIN ZFP14 ZINC FINGER PROTEIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000051157.1|UniProtKB=A0A5F8H5A8 A0A5F8H5A8 LOC100020600 PTHR48002:SF45 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000049581.1|UniProtKB=A0A5F8GBT2 A0A5F8GBT2 MC1R PTHR22750:SF2 G-PROTEIN COUPLED RECEPTOR MELANOCYTE-STIMULATING HORMONE RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 positive regulation of response to stimulus#GO:0048584;biosynthetic process#GO:0009058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;pigment metabolic process#GO:0042440;positive regulation of cellular process#GO:0048522;secondary metabolic process#GO:0019748;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of response to stimulus#GO:0048583;pigment biosynthetic process#GO:0046148;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;phenol-containing compound biosynthetic process#GO:0046189;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;secondary metabolite biosynthetic process#GO:0044550;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;phenol-containing compound metabolic process#GO:0018958;positive regulation of signaling#GO:0023056;melanin biosynthetic process#GO:0042438;regulation of intracellular signal transduction#GO:1902531;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000012295.2|UniProtKB=F7GF25 F7GF25 HSPE1 PTHR10772:SF67 10 KDA HEAT SHOCK PROTEIN 10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;protein-folding chaperone binding#GO:0051087;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 chaperonin#PC00073 MONDO|Ensembl=ENSMODG00000015744.4|UniProtKB=F6PPH2 F6PPH2 TIPARP PTHR45740:SF7 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE TIPARP catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763 post-translational protein modification#GO:0043687;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000013333.4|UniProtKB=F6UYF6 F6UYF6 QRICH1 PTHR45736:SF8 ZINC FINGER MYM-TYPE PROTEIN TRANSCRIPTIONAL REGULATOR QRICH1 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000043034.1|UniProtKB=A0A5F8HDM3 A0A5F8HDM3 RABIF PTHR13276:SF0 GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4 GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 post-Golgi vesicle-mediated transport#GO:0006892;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;membrane#GO:0016020 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000047182.1|UniProtKB=A0A5F8H6L7 A0A5F8H6L7 LOC100026408 PTHR48018:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006209.4|UniProtKB=F6ZSU6 F6ZSU6 RNF207 PTHR22635:SF0 RING FINGER PROTEIN 207 RING FINGER PROTEIN 207 protein binding#GO:0005515;Hsp70 protein binding#GO:0030544;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;transmembrane transporter binding#GO:0044325;heat shock protein binding#GO:0031072 regulation of heart contraction#GO:0008016;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of muscle system process#GO:0090257;regulation of biological process#GO:0050789;regulation of anatomical structure morphogenesis#GO:0022603;regulation of system process#GO:0044057;regulation of muscle contraction#GO:0006937 cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000008730.4|UniProtKB=F6PUB7 F6PUB7 ENKUR PTHR21490:SF0 ENKURIN-RELATED ENKURIN protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 intracellular vesicle#GO:0097708;cytoplasmic microtubule#GO:0005881;vesicle#GO:0031982;organelle#GO:0043226;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule#GO:0005874;axoneme#GO:0005930;supramolecular fiber#GO:0099512;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;microtubule cytoskeleton#GO:0015630;secretory vesicle#GO:0099503;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 MONDO|Ensembl=ENSMODG00000003597.4|UniProtKB=A0A5F8GX34 A0A5F8GX34 RBM19 PTHR23147:SF48 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN 19-RELATED nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;membraneless organelle#GO:0043228 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000039717.1|UniProtKB=A0A5F8H603 A0A5F8H603 PTHR11528:SF87 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-ALPHA ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;binding#GO:0005488;ATP binding#GO:0005524;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367 cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein stabilization#GO:0050821;response to heat#GO:0009408;cellular response to heat#GO:0034605;response to stress#GO:0006950;regulation of protein stability#GO:0031647;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biological regulation#GO:0065007;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266 plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;perinuclear region of cytoplasm#GO:0048471;myelin sheath#GO:0043209;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;intracellular membrane-bounded organelle#GO:0043231;cell body#GO:0044297;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072;Hsp90 family chaperone#PC00028 MONDO|Ensembl=ENSMODG00000014041.3|UniProtKB=F6UQG1 F6UQG1 GID4 PTHR15898:SF13 BIFUNCTIONAL APOPTOSIS REGULATOR GLUCOSE-INDUCED DEGRADATION PROTEIN 4 HOMOLOG catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 MONDO|Ensembl=ENSMODG00000011722.4|UniProtKB=F7FSX9 F7FSX9 RIPOR2 PTHR15829:SF2 PROTEIN KINASE PKN/PRK1, EFFECTOR RHO FAMILY-INTERACTING CELL POLARIZATION REGULATOR 2 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000016847.4|UniProtKB=F6QHR2 F6QHR2 SASH1 PTHR12301:SF3 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED SAM AND SH3 DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584 MONDO|Ensembl=ENSMODG00000045915.1|UniProtKB=H9H6K8 H9H6K8 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000005853.4|UniProtKB=F6TKJ5 F6TKJ5 LOC100026625 PTHR14614:SF172 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000020363.3|UniProtKB=F7FJY9 F7FJY9 LMBRD2 PTHR21355:SF19 G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2 G PROTEIN-COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000006651.5|UniProtKB=K7DZC4 K7DZC4 TPRG1L PTHR31108:SF7 TUMOR PROTEIN P63-REGULATED GENE 1-LIKE PROTEIN TUMOR PROTEIN P63-REGULATED GENE 1-LIKE PROTEIN intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000014164.4|UniProtKB=F6U7Q2 F6U7Q2 NDRG4 PTHR11034:SF21 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG4 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of response to stimulus#GO:0048584;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cell communication#GO:0007154;positive regulation of signaling#GO:0023056 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000025641.3|UniProtKB=F6XW30 F6XW30 CEP72 PTHR23311:SF7 HEAT SHOCK REGULATED 2 CENTROSOMAL PROTEIN OF 72 KDA microtubule organizing center organization#GO:0031023;regulation of localization#GO:0032879;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of protein localization#GO:0032880;microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;organelle assembly#GO:0070925;centrosome cycle#GO:0007098;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriolar satellite#GO:0034451;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000016029.4|UniProtKB=F6ZHU3 F6ZHU3 SLC2A2 PTHR23503:SF27 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180;import across plasma membrane#GO:0098739;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643 apical part of cell#GO:0045177;brush border#GO:0005903;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cluster of actin-based cell projections#GO:0098862;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000009361.4|UniProtKB=F7CPR3 F7CPR3 CEP83 PTHR23170:SF2 NY-REN-58 ANTIGEN CENTROSOMAL PROTEIN OF 83 KDA cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;organelle assembly#GO:0070925;organelle localization#GO:0051640;centrosome localization#GO:0051642;cell projection organization#GO:0030030;establishment of organelle localization#GO:0051656;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 cytoskeleton#GO:0005856;Golgi apparatus#GO:0005794;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;ciliary transition fiber#GO:0097539;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000038948.1|UniProtKB=A0A5F8H7N2 A0A5F8H7N2 SPDYA PTHR31545:SF6 SEEDY PROTEIN A/C FAMILY MEMBER SPEEDY_RINGO CELL CYCLE REGULATOR FAMILY MEMBER A protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;protein binding#GO:0005515 G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047;cell cycle G1/S phase transition#GO:0044843;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007;mitotic cell cycle phase transition#GO:0044772;regulation of cell population proliferation#GO:0042127;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;positive regulation of cell population proliferation#GO:0008284;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794 MONDO|Ensembl=ENSMODG00000010867.4|UniProtKB=A0A5F8G6H7 A0A5F8G6H7 FHL1 PTHR47029:SF2 FOUR AND A HALF LIM DOMAINS PROTEIN 1 FOUR AND A HALF LIM DOMAINS PROTEIN 1 protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 MONDO|Ensembl=ENSMODG00000020739.4|UniProtKB=F7AN53 F7AN53 HSD17B11 PTHR24322:SF489 PKSB ESTRADIOL 17-BETA-DEHYDROGENASE 11 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000042915.1|UniProtKB=A0A5F8H724 A0A5F8H724 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010354.4|UniProtKB=F6RPB6 F6RPB6 MCTS1 PTHR22798:SF0 MCT-1 PROTEIN MALIGNANT T-CELL-AMPLIFIED SEQUENCE 1 translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183;translation#GO:0006412;translational initiation#GO:0006413;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000021284.4|UniProtKB=F7GE95 F7GE95 EIF4A2 PTHR24031:SF762 RNA HELICASE EUKARYOTIC INITIATION FACTOR 4A-II primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nucleus#GO:0005634;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000025760.2|UniProtKB=F7G3K6 F7G3K6 PTHR11430:SF79 LIPOCALIN EPIDIDYMAL-SPECIFIC LIPOCALIN-10 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000020684.4|UniProtKB=A0A5F8GDX2 A0A5F8GDX2 EXOC1 PTHR16092:SF33 SEC3/SYNTAXIN-RELATED EXOCYST COMPLEX COMPONENT 1 phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 establishment of localization#GO:0051234;secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;exocytosis#GO:0006887;secretion by cell#GO:0032940;vesicle-mediated transport to the plasma membrane#GO:0098876;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;Golgi to plasma membrane transport#GO:0006893;export from cell#GO:0140352;cellular process#GO:0009987 cell periphery#GO:0071944;cell cortex#GO:0005938;membrane#GO:0016020;exocyst#GO:0000145;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023 SNARE protein#PC00034;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000029321.2|UniProtKB=K7DZY8 K7DZY8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000014722.3|UniProtKB=F6ZD60 F6ZD60 HLA-DRA PTHR19944:SF86 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN protein-containing complex binding#GO:0044877;binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823 positive regulation of leukocyte activation#GO:0002696;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of T cell activation#GO:0050863;immune system process#GO:0002376;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;regulation of lymphocyte activation#GO:0051249;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;regulation of immune response#GO:0050776;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;positive regulation of cell adhesion#GO:0045785;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794 intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;late endosome membrane#GO:0031902;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 MONDO|Ensembl=ENSMODG00000019220.3|UniProtKB=A0A5F8GUY9 A0A5F8GUY9 PTHR15384:SF0 PROTEIN EVI2B PROTEIN EVI2B regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;biological regulation#GO:0065007;regulation of cell development#GO:0060284;positive regulation of myeloid cell differentiation#GO:0045639;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of immune system process#GO:0002684;regulation of hemopoiesis#GO:1903706;regulation of cell division#GO:0051302;regulation of myeloid cell differentiation#GO:0045637;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789 MONDO|Ensembl=ENSMODG00000050120.1|UniProtKB=A0A5F8H2T6 A0A5F8H2T6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016975.4|UniProtKB=A0A5F8HHL3 A0A5F8HHL3 SEMA3D PTHR11036:SF36 SEMAPHORIN SEMAPHORIN-3D protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 neural crest cell migration#GO:0001755;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;taxis#GO:0042330;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;mesenchymal cell differentiation#GO:0048762;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;neural crest cell differentiation#GO:0014033;cell projection morphogenesis#GO:0048858;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axon guidance#GO:0007411;axon development#GO:0061564;stem cell differentiation#GO:0048863;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;tissue development#GO:0009888;multicellular organismal process#GO:0032501;cell migration#GO:0016477;neural crest cell development#GO:0014032;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;mesenchyme development#GO:0060485;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;cell motility#GO:0048870;regulation of cellular process#GO:0050794;chemotaxis#GO:0006935;stem cell development#GO:0048864;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000017326.3|UniProtKB=F7ENP3 F7ENP3 TMSB4X PTHR12021:SF27 THYMOSIN BETA THYMOSIN BETA-4-LIKE actin monomer binding#GO:0003785;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein sequestering activity#GO:0140311;binding#GO:0005488;molecular sequestering activity#GO:0140313;protein binding#GO:0005515 regulation of cellular process#GO:0050794;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cell migration#GO:0030334;regulation of biological process#GO:0050789 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000005499.3|UniProtKB=F6TT81 F6TT81 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019518.4|UniProtKB=F6VD56 F6VD56 ZNF710 PTHR24390:SF43 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 710 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020120.4|UniProtKB=F7DRE2 F7DRE2 VN2R615 PTHR24061:SF0 CALCIUM-SENSING RECEPTOR-RELATED EXTRACELLULAR CALCIUM-SENSING RECEPTOR-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000012535.4|UniProtKB=A0A5F8H9D0 A0A5F8H9D0 SETX PTHR10887:SF552 DNA2/NAM7 HELICASE FAMILY HELICASE SENATAXIN double-stranded DNA binding#GO:0003690;RNA binding#GO:0003723;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 macromolecule metabolic process#GO:0043170;termination of RNA polymerase II transcription#GO:0006369;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription termination#GO:0006353;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000016376.4|UniProtKB=F7ER84 F7ER84 HBP1 PTHR15499:SF3 HMG BOX-CONTAINING PROTEIN 1 HMG BOX-CONTAINING PROTEIN 1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000007100.4|UniProtKB=F6SWY2 F6SWY2 IGF2R PTHR15071:SF17 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR binding#GO:0005488;protein binding#GO:0005515;growth factor binding#GO:0019838 protein localization to organelle#GO:0033365;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;protein localization to lysosome#GO:0061462;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;protein localization to vacuole#GO:0072665;lysosomal transport#GO:0007041;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;endosome#GO:0005768;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;late endosome#GO:0005770;endomembrane system#GO:0012505;plasma membrane#GO:0005886;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737 membrane traffic protein#PC00150 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885;Apoptosis signaling pathway#P00006>IGFR2#P00282;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895 MONDO|Ensembl=ENSMODG00000046168.1|UniProtKB=A0A5F8GWZ1 A0A5F8GWZ1 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000000529.4|UniProtKB=F6XNE9 F6XNE9 SCP2 PTHR24314:SF20 NON-SPECIFIC LIPID TRANSFER PROTEIN-RELATED STEROL CARRIER PROTEIN 2 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000029243.2|UniProtKB=K7E5Q7 K7E5Q7 PTHR14759:SF34 STOP PROTEIN MUCIN-LIKE DOMAIN-CONTAINING PROTEIN cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular localization#GO:0051641;localization#GO:0051179;regulation of microtubule-based process#GO:0032886 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;cis-Golgi network#GO:0005801;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798 MONDO|Ensembl=ENSMODG00000005417.4|UniProtKB=F7FVE6 F7FVE6 VPS26B PTHR12233:SF5 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26B transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;vesicle-mediated transport#GO:0016192;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;cytosolic transport#GO:0016482 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;retromer complex#GO:0030904;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000023920.2|UniProtKB=F7FY05 F7FY05 SFN PTHR18860:SF14 14-3-3 PROTEIN 14-3-3 PROTEIN SIGMA protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;p53 pathway#P00059>14-3-3#P04628;p53 pathway#P00059>14-3-3#G01576;EGF receptor signaling pathway#P00018>14-3-3#P00539;FGF signaling pathway#P00021>14-3-3#P00624 MONDO|Ensembl=ENSMODG00000000044.4|UniProtKB=K7E4E2 K7E4E2 ARSL PTHR42693:SF48 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE L hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000016272.4|UniProtKB=F7BGQ8 F7BGQ8 CARF PTHR14694:SF1 CALCIUM-RESPONSIVE TRANSCRIPTION FACTOR CALCIUM-RESPONSIVE TRANSCRIPTION FACTOR sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000016788.3|UniProtKB=F7G687 F7G687 PTHR24340:SF72 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000050224.1|UniProtKB=A0A5F8GZG7 A0A5F8GZG7 PTHR34649:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 99 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 99 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000040806.1|UniProtKB=A0A5F8GKY3 A0A5F8GKY3 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005323.4|UniProtKB=F7D289 F7D289 LOC100619446 PTHR11461:SF186 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B4 peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000040498.1|UniProtKB=A0A5F8GMR2 A0A5F8GMR2 PTHR23411:SF39 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 1-RELATED antigen binding#GO:0003823;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;defense response#GO:0006952;response to external stimulus#GO:0009605;immune response#GO:0006955;complement activation#GO:0006956;response to other organism#GO:0051707;adaptive immune response#GO:0002250;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;response to bacterium#GO:0009617;response to external biotic stimulus#GO:0043207;regulation of immune system process#GO:0002682;immune effector process#GO:0002252;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;antibacterial humoral response#GO:0019731;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;defense response to bacterium#GO:0042742;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000010677.4|UniProtKB=F7C1J2 F7C1J2 UBA1 PTHR10953:SF155 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 1 ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a protein#GO:0140096 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;DNA damage response#GO:0006974;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490;Ubiquitin proteasome pathway#P00060>E1#P01492 MONDO|Ensembl=ENSMODG00000015214.4|UniProtKB=F6V4G7 F6V4G7 GAN PTHR24412:SF232 KELCH PROTEIN GIGAXONIN ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013753.4|UniProtKB=F6WS57 F6WS57 NSUN5 PTHR22807:SF4 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 28S RRNA (CYTOSINE-C(5))-METHYLTRANSFERASE catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741 methylation#GO:0032259;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA modification#GO:0009451;positive regulation of protein metabolic process#GO:0051247;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;regulation of biological process#GO:0050789;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;rRNA base methylation#GO:0070475;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;positive regulation of translation#GO:0045727;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;positive regulation of biosynthetic process#GO:0009891;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;post-transcriptional regulation of gene expression#GO:0010608;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000002163.5|UniProtKB=F6YEK7 F6YEK7 TBC1D31 PTHR19853:SF1 WD REPEAT CONTAINING PROTEIN 3 WDR3 TBC1 DOMAIN FAMILY MEMBER 31 cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;cilium#GO:0005929;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025 MONDO|Ensembl=ENSMODG00000013669.4|UniProtKB=F6TXC2 F6TXC2 MAPK13 PTHR24055:SF107 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 13 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;EGF receptor signaling pathway#P00018>p38#P00562;TGF-beta signaling pathway#P00052>P38#P01275;B cell activation#P00010>p38#P00384;FGF signaling pathway#P00021>p38#P00644;p38 MAPK pathway#P05918>p38delta#P06020;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Integrin signalling pathway#P00034>ERK#P00907;Gonadotropin-releasing hormone receptor pathway#P06664>p38#P06831;p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;Ras Pathway#P04393>p38#P04558;Oxidative stress response#P00046>p38#P01135 MONDO|Ensembl=ENSMODG00000004380.4|UniProtKB=F6VTH1 F6VTH1 CTBP1 PTHR46029:SF2 C-TERMINAL-BINDING PROTEIN C-TERMINAL-BINDING PROTEIN 1 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription factor binding#GO:0008134;transcription corepressor activity#GO:0003714;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;transcription regulator activity#GO:0140110;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 Wnt signaling pathway#P00057>C-terminal Binding Protein#P01439 MONDO|Ensembl=ENSMODG00000041460.1|UniProtKB=A0A5F8HKW6 A0A5F8HKW6 GYPC PTHR47614:SF2 GLYCOPHORIN-C GLYCOPHORIN-C cortical cytoskeleton#GO:0030863;membrane#GO:0016020;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000036514.1|UniProtKB=A0A5F8GD53 A0A5F8GD53 PDGFA PTHR11633:SF3 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR SUBUNIT A binding#GO:0005488;signaling receptor binding#GO:0005102;growth factor receptor binding#GO:0070851;protein binding#GO:0005515 positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;positive regulation of locomotion#GO:0040017;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;tube development#GO:0035295;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;system development#GO:0048731;positive regulation of signal transduction#GO:0009967;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;angiogenesis#GO:0001525;positive regulation of signaling#GO:0023056;positive regulation of cell motility#GO:2000147;positive regulation of cell population proliferation#GO:0008284;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;circulatory system development#GO:0072359;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;signaling#GO:0023052 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 PDGF signaling pathway#P00047>PDGF#P01170;Angiogenesis#P00005>PDGF#P00224 MONDO|Ensembl=ENSMODG00000012866.4|UniProtKB=F7C935 F7C935 PTHR23267:SF511 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-9 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000036590.1|UniProtKB=A0A5F8GUJ3 A0A5F8GUJ3 monDomV1R1232 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018406.4|UniProtKB=F6Q9I8 F6Q9I8 RAD52 PTHR12132:SF1 DNA REPAIR AND RECOMBINATION PROTEIN RAD52, RAD59 DNA REPAIR PROTEIN RAD52 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;double-strand break repair via homologous recombination#GO:0000724;double-strand break repair via single-strand annealing#GO:0045002;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;mitotic recombination#GO:0006312;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;telomere organization#GO:0032200 intracellular organelle#GO:0043229;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000037355.1|UniProtKB=A0A5F8HGV9 A0A5F8HGV9 PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN protein binding#GO:0005515;peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488;signaling receptor binding#GO:0005102 positive regulation of immune system process#GO:0002684;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of leukocyte mediated cytotoxicity#GO:0001910 side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000000453.5|UniProtKB=F6USH5 F6USH5 HOXA11 PTHR46092:SF3 HOMEOBOX PROTEIN HOX-A11-RELATED HOMEOBOX PROTEIN HOX-A11 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;regulation of primary metabolic process#GO:0080090;skeletal system morphogenesis#GO:0048705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000021143.4|UniProtKB=H9H660 H9H660 PTHR15036:SF52 PIKACHURIN-LIKE PROTEIN NEUREXIN-2 protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888 protein localization to cell junction#GO:1902414;organelle assembly#GO:0070925;cognition#GO:0050890;synapse organization#GO:0050808;localization#GO:0051179;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;postsynaptic specialization organization#GO:0099084;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;postsynapse organization#GO:0099173;developmental process#GO:0032502;system process#GO:0003008;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;postsynaptic density organization#GO:0097106;nervous system process#GO:0050877;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;synapse assembly#GO:0007416;signaling#GO:0023052;excitatory synapse assembly#GO:1904861;protein localization to synapse#GO:0035418;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;cellular process#GO:0009987;postsynaptic density assembly#GO:0097107;cellular component assembly#GO:0022607;nervous system development#GO:0007399 cell junction#GO:0030054;presynaptic active zone#GO:0048786;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;synapse#GO:0045202;cellular anatomical structure#GO:0110165;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;presynaptic active zone membrane#GO:0048787 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000003389.4|UniProtKB=F6Z127 F6Z127 ABCC2 PTHR24223:SF176 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 2 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;xenobiotic transmembrane transporter activity#GO:0042910;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000007980.4|UniProtKB=F7D6A3 F7D6A3 RAB27A PTHR47977:SF20 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-27A heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094 export from cell#GO:0140352;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940;secretion#GO:0046903;regulation of secretion#GO:0051046;localization#GO:0051179;positive regulation of secretion#GO:0051047;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;positive regulation of transport#GO:0051050;exocytosis#GO:0006887;regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of localization#GO:0051234;transport#GO:0006810 intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;melanosome#GO:0042470;transport vesicle#GO:0030133;plasma membrane region#GO:0098590;endomembrane system#GO:0012505 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000027369.2|UniProtKB=A0A5F8GNL2 A0A5F8GNL2 CTRC PTHR24250:SF35 CHYMOTRYPSIN-RELATED CHYMOTRYPSIN-C catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 protein modifying enzyme#PC00260;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000013312.5|UniProtKB=A0A5F8GYR8 A0A5F8GYR8 WDR20 PTHR14107:SF5 WD REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 20 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;peptidase activator activity#GO:0016504;peptidase regulator activity#GO:0061134 negative regulation of protein catabolic process#GO:0042177;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000008440.4|UniProtKB=F7CCJ4 F7CCJ4 GALNT18 PTHR11675:SF37 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 18 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000043017.1|UniProtKB=A0A5F8G799 A0A5F8G799 LOC100619624 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000003578.4|UniProtKB=F7FQB7 F7FQB7 SMARCA2 PTHR10799:SF541 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 2 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094 regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;heterochromatin formation#GO:0031507;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 DNA helicase#PC00011;DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000044786.1|UniProtKB=A0A5F8HA79 A0A5F8HA79 WNT4 PTHR12027:SF101 WNT RELATED PROTEIN WNT-4 signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 MONDO|Ensembl=ENSMODG00000005316.4|UniProtKB=F7DLI8 F7DLI8 HSDL2 PTHR42808:SF3 HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000011421.4|UniProtKB=F6RKI8 F6RKI8 RHPN1 PTHR23031:SF6 RHOPHILIN RHOPHILIN-1 regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of actin filament bundle assembly#GO:0032231;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cytoskeleton organization#GO:0051494 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000796.4|UniProtKB=F6S9U5 F6S9U5 PTHR24302:SF38 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A5 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000013371.4|UniProtKB=F7DTJ4 F7DTJ4 NUDT21 PTHR13047:SF0 PRE-MRNA CLEAVAGE FACTOR IM, 25KD SUBUNIT CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 5 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000013502.3|UniProtKB=F7F8D1 F7F8D1 PPIL1 PTHR45625:SF18 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 1 catalytic activity#GO:0003824;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;cis-trans isomerase activity#GO:0016859;catalytic activity, acting on a protein#GO:0140096 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000029432.2|UniProtKB=K7E1P2 K7E1P2 LOC103097378 PTHR16423:SF12 TREM-LIKE TRANSCRIPT PROTEIN TREM-LIKE TRANSCRIPT 2 PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000020637.5|UniProtKB=F7FXD1 F7FXD1 TET2 PTHR23358:SF3 METHYLCYTOSINE DIOXYGENASE TET METHYLCYTOSINE DIOXYGENASE TET2 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;hemopoiesis#GO:0030097;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biological process#GO:0050789;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell development#GO:0048468;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000019715.3|UniProtKB=F6XMF9 F6XMF9 PTHR48001:SF165 OLFACTORY RECEPTOR OLFACTORY RECEPTOR FAMILY 1 SUBFAMILY AH MEMBER 3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000043856.1|UniProtKB=A0A5F8GBT7 A0A5F8GBT7 monDomV1R1229 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000050352.1|UniProtKB=A0A5F8H7B2 A0A5F8H7B2 PDIK1L PTHR11042:SF58 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED SERINE_THREONINE-PROTEIN KINASE PDIK1L protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of translational initiation#GO:0006446;post-transcriptional regulation of gene expression#GO:0010608 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000001018.4|UniProtKB=F6ZFD1 F6ZFD1 TRPV6 PTHR10582:SF25 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 6 calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;calcium ion transport#GO:0006816;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion import#GO:0070509;calcium ion transmembrane transport#GO:0070588;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000001894.3|UniProtKB=F6WGE6 F6WGE6 CFAP36 PTHR21532:SF0 PHOSPHODIESTERASE HL CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 36 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;axoneme#GO:0005930;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;ciliary base#GO:0097546 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000042527.1|UniProtKB=A0A5F8GK91 A0A5F8GK91 PTHR11414:SF20 CYSTATIN FAMILY MEMBER CYSTATIN-A peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000004124.4|UniProtKB=A0A5F8GKV2 A0A5F8GKV2 DCTD PTHR11086:SF23 DEOXYCYTIDYLATE DEAMINASE-RELATED DEOXYCYTIDYLATE DEAMINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824 nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleoside monophosphate biosynthetic process#GO:0009124;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;organophosphate metabolic process#GO:0019637 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 hydrolase#PC00121;deaminase#PC00088 MONDO|Ensembl=ENSMODG00000043944.1|UniProtKB=A0A5F8GWJ7 A0A5F8GWJ7 PTHR16717:SF1 CYTOCHROME C OXIDASE POLYPEPTIDE VIII CYTOCHROME C OXIDASE SUBUNIT 8A, MITOCHONDRIAL transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;oxidase#PC00175;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000025722.3|UniProtKB=A0A5F8GTZ4 A0A5F8GTZ4 PBLD PTHR13774:SF17 PHENAZINE BIOSYNTHESIS PROTEIN PHENAZINE BIOSYNTHESIS-LIKE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000018736.4|UniProtKB=A0A5F8HDI8 A0A5F8HDI8 BCL9 PTHR15185:SF5 BCL9 B-CELL CLL_LYMPHOMA 9 PROTEIN binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;canonical Wnt signaling pathway#GO:0060070;cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 Wnt signaling pathway#P00057>Bcl9#P01450 MONDO|Ensembl=ENSMODG00000008103.3|UniProtKB=F7G5V2 F7G5V2 GJA3 PTHR11984:SF12 CONNEXIN GAP JUNCTION ALPHA-3 PROTEIN wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;anchoring junction#GO:0070161 gap junction#PC00105;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000000500.4|UniProtKB=F6TU68 F6TU68 SMAD1 PTHR13703:SF23 SMAD SMAD FAMILY MEMBER 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515 response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular response to growth factor stimulus#GO:0071363;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to growth factor#GO:0070848;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;response to transforming growth factor beta#GO:0071559;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;response to BMP#GO:0071772 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD1/5/8#P06787;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292;Wnt signaling pathway#P00057>Smad4#P01455 MONDO|Ensembl=ENSMODG00000040506.1|UniProtKB=A0A5F8GNG0 A0A5F8GNG0 LOC100029087 PTHR19229:SF274 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ABC-TYPE ORGANIC ANION TRANSPORTER ABCA8 ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876;localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000020505.4|UniProtKB=F6UPD9 F6UPD9 C12orf50 PTHR15725:SF1 ZN-FINGER, C-X8-C-X5-C-X3-H TYPE-CONTAINING RIKEN CDNA 1700017N19 GENE RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;biosynthetic process#GO:0009058;gene expression#GO:0010467;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000012748.4|UniProtKB=F6T0Z7 F6T0Z7 MED22 PTHR12434:SF6 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000012964.4|UniProtKB=F7A9E4 F7A9E4 BCL11B PTHR45993:SF4 B-CELL LYMPHOMA/LEUKEMIA 11 B-CELL LYMPHOMA_LEUKEMIA 11B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000027671.2|UniProtKB=K7E5E3 K7E5E3 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025342.2|UniProtKB=F6ZAY9 F6ZAY9 PTHR13710:SF162 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;chromosome#GO:0005694;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA helicase#PC00011;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000028303.2|UniProtKB=K7E676 K7E676 PTHR12080:SF18 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE SLAM FAMILY MEMBER 9 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;immune system process#GO:0002376;cell activation#GO:0001775;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;leukocyte activation#GO:0045321;T cell activation#GO:0042110;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000046510.1|UniProtKB=A0A5F8GW44 A0A5F8GW44 LOC100618004 PTHR13042:SF0 UBIQUITIN-LIKE PROTEIN 5 UBIQUITIN-LIKE PROTEIN 5 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000003088.4|UniProtKB=A0A5F8G7W9 A0A5F8G7W9 DGKD PTHR11255:SF30 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE DELTA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 neutral lipid metabolic process#GO:0006638;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biological regulation#GO:0065007;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;signal transduction#GO:0007165;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 kinase#PC00137;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000047853.1|UniProtKB=A0A5F8GV02 A0A5F8GV02 INHA PTHR11848:SF117 TGF-BETA FAMILY INHIBIN ALPHA CHAIN cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>Inha#P06855 MONDO|Ensembl=ENSMODG00000009307.3|UniProtKB=A0A5F8GL44 A0A5F8GL44 SEC14L2 PTHR23324:SF90 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 2 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000015733.4|UniProtKB=F7B530 F7B530 TMEM212 PTHR23320:SF130 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED TRANSMEMBRANE PROTEIN 212 transporter#PC00227 MONDO|Ensembl=ENSMODG00000025632.2|UniProtKB=A0A5F8GE23 A0A5F8GE23 GNG7 PTHR13809:SF8 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-7 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 catalytic complex#GO:1902494;cytoplasmic side of membrane#GO:0098562;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;membrane protein complex#GO:0098796;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Enkephalin release#P05913>G-Protein (s)#P05977;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (i)#P05974;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;GABA-B receptor II signaling#P05731>Ggamma#P05754;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Wnt signaling pathway#P00057>Ggamma#P01465 MONDO|Ensembl=ENSMODG00000003201.3|UniProtKB=F6VFX4 F6VFX4 HAS3 PTHR22913:SF6 HYALURONAN SYNTHASE HYALURONAN SYNTHASE 3 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 carbohydrate derivative biosynthetic process#GO:1901137;glycosaminoglycan biosynthetic process#GO:0006024;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;extracellular matrix assembly#GO:0085029;cellular component assembly#GO:0022607;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;aminoglycan metabolic process#GO:0006022;polysaccharide biosynthetic process#GO:0000271;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;glycosaminoglycan metabolic process#GO:0030203;aminoglycan biosynthetic process#GO:0006023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000014283.4|UniProtKB=A0A5F8H8P5 A0A5F8H8P5 RPS6KA1 PTHR24351:SF43 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;TOR signaling#GO:0031929;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;signaling#GO:0023052;positive regulation of RNA metabolic process#GO:0051254;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;TORC1 signaling#GO:0038202;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 protein modifying enzyme#PC00260 CCKR signaling map#P06959>RSK1/2#P07153;PDGF signaling pathway#P00047>p90RSK#P01142;Ras Pathway#P04393>p90RSK#P04541;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;Interleukin signaling pathway#P00036>p90RSK#P00964 MONDO|Ensembl=ENSMODG00000011026.4|UniProtKB=F7F4H6 F7F4H6 ALDH3A2 PTHR43570:SF9 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE FAMILY 3 MEMBER A2 catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;metabolic process#GO:0008152 membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 MONDO|Ensembl=ENSMODG00000011208.4|UniProtKB=F6SQC6 F6SQC6 PIGL PTHR12993:SF11 N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE deacetylase activity#GO:0019213;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;deacylase activity#GO:0160215;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 deacetylase#PC00087 MONDO|Ensembl=ENSMODG00000004981.4|UniProtKB=F7FKR0 F7FKR0 CNPY1 PTHR13341:SF4 MIR-INTERACTING SAPOSIN-LIKE PROTEIN CANOPY FGF SIGNALING REGULATOR 1 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000015139.3|UniProtKB=F7CZN8 F7CZN8 ARHGEF18 PTHR13944:SF23 AGAP007712-PA RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 18 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of signal transduction#GO:0009966;intracellular signaling cassette#GO:0141124;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000001652.4|UniProtKB=F6T758 F6T758 SEPTIN9 PTHR18884:SF47 SEPTIN SEPTIN-9 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 cell cycle#GO:0007049;macromolecule localization#GO:0033036;cell division#GO:0051301;cell cycle process#GO:0022402;cellular process#GO:0009987;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;intracellular protein localization#GO:0008104 cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cell periphery#GO:0071944;cell cortex#GO:0005938;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000011666.3|UniProtKB=A0A5F8HKB0 A0A5F8HKB0 ACSBG1 PTHR24096:SF296 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE ACSBG1 ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ligase#PC00142 MONDO|Ensembl=ENSMODG00000017380.4|UniProtKB=A0A5F8HCP5 A0A5F8HCP5 TMEM54 PTHR31258:SF2 KERATINOCYTE-ASSOCIATED PROTEIN 3 TRANSMEMBRANE PROTEIN 54 MONDO|Ensembl=ENSMODG00000044721.1|UniProtKB=A0A5F8GBH5 A0A5F8GBH5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008857.4|UniProtKB=F7CUC2 F7CUC2 C5AR1 PTHR24225:SF29 CHEMOTACTIC RECEPTOR C5A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR 1 immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of immune response#GO:0050776;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000048531.1|UniProtKB=A0A5F8GKD4 A0A5F8GKD4 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000018599.4|UniProtKB=F7BQ26 F7BQ26 COPB2 PTHR19876:SF2 COATOMER COATOMER SUBUNIT BETA' retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;vesicle coat#GO:0030120;cytoplasm#GO:0005737;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular organelle#GO:0043229;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796 vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000019325.3|UniProtKB=F6XTA6 F6XTA6 CRYBA1 PTHR11818:SF8 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN A3 structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;sensory system development#GO:0048880;multicellular organism development#GO:0007275;animal organ development#GO:0048513;system process#GO:0003008;sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;visual perception#GO:0007601;visual system development#GO:0150063;sensory perception of light stimulus#GO:0050953;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;sensory perception#GO:0007600;nervous system process#GO:0050877 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000005944.3|UniProtKB=A0A5F8GNM2 A0A5F8GNM2 ARL6IP1 PTHR20952:SF0 ADP-RIBOSYLATION-LIKE FACTOR 6-INTERACTING PROTEIN ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 1 endoplasmic reticulum membrane organization#GO:0090158;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;endoplasmic reticulum tubular network organization#GO:0071786;cellular component assembly#GO:0022607 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum tubular network#GO:0071782;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000018012.4|UniProtKB=F7AKK5 F7AKK5 SEC63 PTHR24075:SF0 SEC63 DOMAIN-CONTAINING TRANSLOCATION PROTEIN SEC63 HOMOLOG RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization within membrane#GO:0051668;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein targeting to membrane#GO:0006612;establishment of protein localization to endoplasmic reticulum#GO:0072599;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting#GO:0006605;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796;rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;rough endoplasmic reticulum#GO:0005791;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017945.5|UniProtKB=F7E3E8 F7E3E8 WASF1 PTHR12902:SF8 WASP-1 ACTIN-BINDING PROTEIN WASF1 protein kinase A binding#GO:0051018;binding#GO:0005488;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular component organization#GO:0051130;actin filament-based process#GO:0030029;positive regulation of organelle organization#GO:0010638;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cell leading edge#GO:0031252;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000029529.2|UniProtKB=A0A5F8GIJ9 A0A5F8GIJ9 GARIN1A PTHR22574:SF10 FAMILY NOT NAMED GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 1A MONDO|Ensembl=ENSMODG00000047560.1|UniProtKB=K7E4L7 K7E4L7 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000000015.3|UniProtKB=F6SIF5 F6SIF5 PTHR23420:SF2 ADENOSYLHOMOCYSTEINASE S-ADENOSYLHOMOCYSTEINE HYDROLASE-LIKE PROTEIN 2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;proteinogenic amino acid metabolic process#GO:0170039;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000003179.4|UniProtKB=F6VY71 F6VY71 TSTD2 PTHR43268:SF6 THIOSULFATE SULFURTRANSFERASE/RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2 THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2 transferase#PC00220 MONDO|Ensembl=ENSMODG00000045473.1|UniProtKB=A0A5F8G8P1 A0A5F8G8P1 PTHR10223:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4 protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;modification-dependent protein binding#GO:0140030 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;proteasome complex#GO:0000502;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;protease#PC00190 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000039760.1|UniProtKB=A0A5F8H0V6 A0A5F8H0V6 CMTM7 PTHR22776:SF89 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 7 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;immune response#GO:0006955;activation of innate immune response#GO:0002218;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;leukocyte activation#GO:0045321;cell communication#GO:0007154;cell activation#GO:0001775;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of response to external stimulus#GO:0032101;lymphocyte activation#GO:0046649;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;B cell activation#GO:0042113;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;signaling#GO:0023052;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;toll-like receptor signaling pathway#GO:0002224;immune system process#GO:0002376 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000002018.5|UniProtKB=A0A5F8GL94 A0A5F8GL94 LRRC41 PTHR15354:SF1 MUF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 41 catalytic complex#GO:1902494;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;Cul5-RING ubiquitin ligase complex#GO:0031466;ubiquitin ligase complex#GO:0000151 MONDO|Ensembl=ENSMODG00000003012.4|UniProtKB=A0A5F8G8B8 A0A5F8G8B8 AFAP1 PTHR14338:SF8 ACTIN FILAMENT-ASSOCIATED PROTEIN 1 FAMILY MEMBER ACTIN FILAMENT-ASSOCIATED PROTEIN 1 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytosol#GO:0005829;actin cytoskeleton#GO:0015629 MONDO|Ensembl=ENSMODG00000012329.3|UniProtKB=F7E2Q8 F7E2Q8 HOXB9 PTHR45970:SF5 AGAP004664-PA HOMEOBOX PROTEIN HOX-B9 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;skeletal system morphogenesis#GO:0048705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;skeletal system development#GO:0001501;embryo development#GO:0009790;anterior/posterior pattern specification#GO:0009952;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000002725.4|UniProtKB=F6Z7G5 F6Z7G5 PSMC1 PTHR23073:SF24 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 4 isomerase activity#GO:0016853;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 proteasome complex#GO:0000502;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000016180.3|UniProtKB=F7G8N2 F7G8N2 DBNDD2 PTHR16294:SF7 DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN DYSBINDIN DOMAIN-CONTAINING PROTEIN 2 regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 MONDO|Ensembl=ENSMODG00000020456.4|UniProtKB=F7A302 F7A302 PTHR11875:SF70 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1 LIKE 6 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;chromatin remodeling#GO:0006338;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000017600.4|UniProtKB=F6Y2G6 F6Y2G6 HEATR5A PTHR21663:SF1 HYPOTHETICAL HEAT DOMAIN-CONTAINING HEAT REPEAT-CONTAINING PROTEIN 5A intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036 membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708 MONDO|Ensembl=ENSMODG00000003882.4|UniProtKB=F7DT59 F7DT59 TBC1D9B PTHR22957:SF225 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 9B enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000023304.1|UniProtKB=F6VB69 F6VB69 LOC100031601 PTHR11406:SF0 PHOSPHOGLYCERATE KINASE PHOSPHOGLYCERATE KINASE nucleotide binding#GO:0000166;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;catalytic activity#GO:0003824;phosphoglycerate kinase activity#GO:0004618;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;kinase activity#GO:0016301;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;purine ribonucleoside triphosphate binding#GO:0035639;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488 ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;pyruvate metabolic process#GO:0006090;ADP catabolic process#GO:0046032;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate biosynthetic process#GO:0016051;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate catabolic process#GO:1901292;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;ADP metabolic process#GO:0046031;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;oxoacid metabolic process#GO:0043436;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;ribonucleoside diphosphate metabolic process#GO:0009185;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;gluconeogenesis#GO:0006094;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;nucleoside diphosphate catabolic process#GO:0009134;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleotide catabolic process#GO:0009166;small molecule biosynthetic process#GO:0044283;energy derivation by oxidation of organic compounds#GO:0015980;nucleobase-containing compound catabolic process#GO:0034655;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphoglycerate kinase#P00671 MONDO|Ensembl=ENSMODG00000024203.3|UniProtKB=A0A5F8HE01 A0A5F8HE01 CFAP97D1 PTHR33768:SF5 MIP11318P SPERM AXONEMAL MAINTENANCE PROTEIN CFAP97D1 MONDO|Ensembl=ENSMODG00000002586.4|UniProtKB=F7G531 F7G531 CD247 PTHR10035:SF2 T-CELL SURFACE GLYCOPROTEIN CD3 ZETA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 ZETA CHAIN immune response-activating signaling pathway#GO:0002757;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;regulation of immune response#GO:0050776;immune system process#GO:0002376;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 T cell activation#P00053>TCR zeta#P01296 MONDO|Ensembl=ENSMODG00000006138.5|UniProtKB=F6TI50 F6TI50 ESPN PTHR24153:SF14 ESPIN ESPIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;cellular component organization#GO:0016043;cell projection organization#GO:0030030;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin-based cell projection#GO:0098858;neuron projection#GO:0043005;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;stereocilium#GO:0032420 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000050760.1|UniProtKB=A0A5F8HFG0 A0A5F8HFG0 LOC103096610 PTHR23226:SF430 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 1010-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010555.3|UniProtKB=F6YRK9 F6YRK9 CXXC1 PTHR46174:SF1 CXXC-TYPE ZINC FINGER PROTEIN 1 CXXC-TYPE ZINC FINGER PROTEIN 1 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000003959.4|UniProtKB=A0A5F8G6V6 A0A5F8G6V6 PDZRN3 PTHR15545:SF5 PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4 E3 UBIQUITIN-PROTEIN LIGASE PDZRN3 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;neuromuscular junction development#GO:0007528;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;cell junction organization#GO:0034330;protein modification by small protein conjugation#GO:0032446;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;synapse organization#GO:0050808;protein modification by small protein conjugation or removal#GO:0070647 neuromuscular junction#GO:0031594;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000020361.4|UniProtKB=F7FK00 F7FK00 SKP2 PTHR16134:SF32 F-BOX/TPR REPEAT PROTEIN POF3 S-PHASE KINASE-ASSOCIATED PROTEIN 2 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;proteasomal protein catabolic process#GO:0010498;positive regulation of macromolecule metabolic process#GO:0010604;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of double-strand break repair via homologous recombination#GO:0010569;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of DNA recombination#GO:0000018;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of DNA repair#GO:0045739;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;positive regulation of DNA metabolic process#GO:0051054;primary metabolic process#GO:0044238;positive regulation of double-strand break repair#GO:2000781;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;regulation of double-strand break repair#GO:2000779;protein metabolic process#GO:0019538 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000014213.4|UniProtKB=F6T9Y7 F6T9Y7 PTHR11802:SF471 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE CARBOXYPEPTIDASE serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000023765.3|UniProtKB=A0A5F8GEE1 A0A5F8GEE1 PTHR11258:SF3 2-5 OLIGOADENYLATE SYNTHETASE 2'-5'-OLIGOADENYLATE SYNTHASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;adenylyltransferase activity#GO:0070566;double-stranded RNA binding#GO:0003725 response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;antiviral innate immune response#GO:0140374;cellular response to stimulus#GO:0051716;response to virus#GO:0009615;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;defense response to virus#GO:0051607;response to peptide#GO:1901652;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular process#GO:0009987;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cell surface receptor signaling pathway#GO:0007166 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226 nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000042266.1|UniProtKB=A0A5F8GMH6 A0A5F8GMH6 LOC103094021 PTHR11431:SF134 FERRITIN FERRITIN HEAVY CHAIN small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;ferrous iron binding#GO:0008198;iron ion binding#GO:0005506 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 storage protein#PC00210 MONDO|Ensembl=ENSMODG00000008879.4|UniProtKB=F7GHL5 F7GHL5 LOC100018508 PTHR45690:SF15 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 14 regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000006703.3|UniProtKB=F7DGZ4 F7DGZ4 PTHR24381:SF479 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 432 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016390.4|UniProtKB=A0A5F8GSG6 A0A5F8GSG6 ZFP64 PTHR24403:SF43 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 64 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000039642.1|UniProtKB=A0A5F8HEH5 A0A5F8HEH5 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000003093.4|UniProtKB=F6PIW4 F6PIW4 TDRD7 PTHR22948:SF14 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 7 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013680.3|UniProtKB=F6QQ58 F6QQ58 MDH2 PTHR11540:SF76 MALATE AND LACTATE DEHYDROGENASE MALATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000019209.4|UniProtKB=F6ZI91 F6ZI91 RAB11FIP4 PTHR15726:SF5 RAB11-FAMILY INTERACTING PROTEIN RAB11 FAMILY-INTERACTING PROTEIN 4 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;endocytic recycling#GO:0032456;regulation of cell cycle#GO:0051726;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876 cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;cell division site#GO:0032153;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;recycling endosome#GO:0055037;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;cleavage furrow#GO:0032154;vesicle#GO:0031982;intracellular vesicle#GO:0097708;midbody#GO:0030496;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 MONDO|Ensembl=ENSMODG00000021359.4|UniProtKB=H9H800 H9H800 PTHR33906:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 25 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 25 HOMOLOG cellular process#GO:0009987;signal transduction#GO:0007165;male gamete generation#GO:0048232;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;spermatogenesis#GO:0007283;developmental process involved in reproduction#GO:0003006;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;gamete generation#GO:0007276;response to stimulus#GO:0050896;reproductive process#GO:0022414;signaling#GO:0023052;sexual reproduction#GO:0019953;cell communication#GO:0007154;multicellular organismal reproductive process#GO:0048609;smoothened signaling pathway#GO:0007224 intraciliary transport particle B#GO:0030992;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cilium#GO:0005929;intracellular organelle#GO:0043229;intraciliary transport particle#GO:0030990;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000001063.2|UniProtKB=F6YR15 F6YR15 PTHR47230:SF1 TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1 TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 cellular response to stimulus#GO:0051716;positive regulation of type I interferon production#GO:0032481;innate immune response-activating signaling pathway#GO:0002758;positive regulation of signal transduction#GO:0009967;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;activation of innate immune response#GO:0002218;regulation of cytokine production#GO:0001817;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;pattern recognition receptor signaling pathway#GO:0002221;regulation of gene expression#GO:0010468;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;positive regulation of multicellular organismal process#GO:0051240;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;toll-like receptor signaling pathway#GO:0002224;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;positive regulation of signaling#GO:0023056;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of response to external stimulus#GO:0032103;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;immune response-activating signaling pathway#GO:0002757 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TRIF#P01344 MONDO|Ensembl=ENSMODG00000046608.1|UniProtKB=A0A5F8HHW6 A0A5F8HHW6 PTHR10204:SF33 NAD P H OXIDOREDUCTASE-RELATED RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE] catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000009892.4|UniProtKB=F6VCC6 F6VCC6 RREB1 PTHR46451:SF1 RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1 RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1 transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000011857.4|UniProtKB=A0A5F8GVJ8 A0A5F8GVJ8 CHRNA5 PTHR18945:SF76 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-5 transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;acetylcholine receptor activity#GO:0015464;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089 neuromuscular synaptic transmission#GO:0007274;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;transport#GO:0006810;establishment of localization#GO:0051234;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;modulation of chemical synaptic transmission#GO:0050804 transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNA5#P06593;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 MONDO|Ensembl=ENSMODG00000029590.2|UniProtKB=K7E602 K7E602 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000020356.4|UniProtKB=A0A5F8HIK8 A0A5F8HIK8 TKFC PTHR28629:SF4 TRIOKINASE/FMN CYCLASE TRIOKINASE_FMN CYCLASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cyclase#PC00079 MONDO|Ensembl=ENSMODG00000004760.3|UniProtKB=F6X165 F6X165 COTL1 PTHR10829:SF25 CORTACTIN AND DREBRIN COACTOSIN-LIKE PROTEIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament polymerization#GO:0030833;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840 actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;actin filament#GO:0005884;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000038921.1|UniProtKB=F6TKV2 F6TKV2 UAP1L1 PTHR11952:SF6 UDP- GLUCOSE PYROPHOSPHORYLASE UDP-N-ACETYLHEXOSAMINE PYROPHOSPHORYLASE-LIKE PROTEIN 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-sugar metabolic process#GO:0009225;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;UDP-N-acetylglucosamine metabolic process#GO:0006047;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine biosynthetic process#GO:0006048 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000010408.3|UniProtKB=F6PVW2 F6PVW2 PTHR10177:SF70 CYCLINS G1_S-SPECIFIC CYCLIN-E2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234 mitotic cell cycle process#GO:1903047;positive regulation of mitotic cell cycle#GO:0045931;positive regulation of cell cycle G1/S phase transition#GO:1902808;G1/S transition of mitotic cell cycle#GO:0000082;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;positive regulation of cell cycle#GO:0045787;positive regulation of biological process#GO:0048518;cell cycle G1/S phase transition#GO:0044843;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;mitotic cell cycle phase transition#GO:0044772;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;nucleus#GO:0005634;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234 kinase activator#PC00138 Parkinson disease#P00049>Cyclin E#P01213;Cell cycle#P00013>CdkC#P00489 MONDO|Ensembl=ENSMODG00000036815.1|UniProtKB=A0A5F8H7F3 A0A5F8H7F3 PTHR37885:SF1 CMT1A DUPLICATED REGION TRANSCRIPT 4 PROTEIN CMT1A DUPLICATED REGION TRANSCRIPT 4 PROTEIN MONDO|Ensembl=ENSMODG00000020746.4|UniProtKB=F6ZZX9 F6ZZX9 TMPRSS11A PTHR24253:SF41 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 11A peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000000236.4|UniProtKB=F6SGG3 F6SGG3 GPR83 PTHR24238:SF82 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 83 neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;neuropeptide signaling pathway#GO:0007218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013843.4|UniProtKB=F6X6J8 F6X6J8 USF2 PTHR46117:SF2 FI24210P1 UPSTREAM STIMULATORY FACTOR 2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055 PDGF signaling pathway#P00047>c-fos#P01145 MONDO|Ensembl=ENSMODG00000048343.1|UniProtKB=A0A5F8HBS8 A0A5F8HBS8 MPZL3 PTHR13869:SF20 MYELIN P0 RELATED MYELIN PROTEIN ZERO-LIKE PROTEIN 3 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 myelin protein#PC00161 MONDO|Ensembl=ENSMODG00000045759.1|UniProtKB=A0A5F8G551 A0A5F8G551 PTHR48002:SF21 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010700.4|UniProtKB=H9H6E6 H9H6E6 SUPV3L1 PTHR12131:SF31 ATP-DEPENDENT RNA AND DNA HELICASE ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial RNA 3'-end processing#GO:0000965;nucleic acid biosynthetic process#GO:0141187;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000045501.1|UniProtKB=A0A5F8GJM6 A0A5F8GJM6 PTHR10339:SF24 ADP-RIBOSYLTRANSFERASE T-CELL ECTO-ADP-RIBOSYLTRANSFERASE 1-RELATED glycosyltransferase activity#GO:0016757;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763 transferase#PC00220 MONDO|Ensembl=ENSMODG00000015215.3|UniProtKB=F6V4F8 F6V4F8 VWA7 PTHR14905:SF7 NG37 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 7 MONDO|Ensembl=ENSMODG00000000885.4|UniProtKB=F7A851 F7A851 FAM135B PTHR12482:SF3 LIPASE ROG1-RELATED-RELATED PROTEIN FAM135B hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 MONDO|Ensembl=ENSMODG00000018509.4|UniProtKB=K7E3M6 K7E3M6 ANKRD16 PTHR24173:SF95 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000023548.1|UniProtKB=F7C8Z4 F7C8Z4 PTHR48001:SF56 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1Q1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048457.1|UniProtKB=A0A5F8HJ68 A0A5F8HJ68 TXNDC9 PTHR21148:SF11 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000019728.4|UniProtKB=F6X4S3 F6X4S3 ARSB PTHR10342:SF276 ARYLSULFATASE ARYLSULFATASE B hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 MONDO|Ensembl=ENSMODG00000005822.4|UniProtKB=F6U200 F6U200 PTHR10676:SF356 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 14 macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;microtubule motor activity#GO:0003777;protein binding#GO:0005515 cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017 9+2 motile cilium#GO:0097729;cilium#GO:0005929;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000002107.4|UniProtKB=A0A5F8H2W9 A0A5F8H2W9 CERT1 PTHR19308:SF53 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN CERAMIDE TRANSFER PROTEIN lipid transport#GO:0006869;ceramide transport#GO:0035627;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;intracellular transport#GO:0046907;lipid localization#GO:0010876;transport#GO:0006810 MONDO|Ensembl=ENSMODG00000036469.1|UniProtKB=F6Z5E5 F6Z5E5 PTHR48018:SF157 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011782.4|UniProtKB=F7CVQ8 F7CVQ8 ABHD14B PTHR46197:SF2 PROTEIN ABHD14B-LIKE PROTEIN-LYSINE DEACYLASE ABHD14B-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000049713.1|UniProtKB=A0A5F8GHJ4 A0A5F8GHJ4 PTHR24055:SF171 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 6 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 VEGF signaling pathway#P00056>MEK#P01402;PDGF signaling pathway#P00047>ERK#P01143;Angiogenesis#P00005>MEK#P00225;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Interleukin signaling pathway#P00036>ERK#P00965;Integrin signalling pathway#P00034>ERK#P00907 MONDO|Ensembl=ENSMODG00000018819.4|UniProtKB=F6YYR9 F6YYR9 EFHC1 PTHR12086:SF9 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cilium or flagellum-dependent cell motility#GO:0001539;cytokinesis#GO:0000910;microtubule cytoskeleton organization#GO:0000226;cilium-dependent cell motility#GO:0060285;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell division#GO:0051301;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;mitotic cytokinesis#GO:0000281;mitotic spindle organization#GO:0007052;cell motility#GO:0048870;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010 cilium#GO:0005929;intracellular organelle#GO:0043229;microtubule#GO:0005874;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoplasmic microtubule#GO:0005881;organelle#GO:0043226;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;spindle#GO:0005819;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000017994.4|UniProtKB=F7B7W4 F7B7W4 FOXO3 PTHR45767:SF4 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O3-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;response to nutrient levels#GO:0031667;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;response to starvation#GO:0042594;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 winged helix/forkhead transcription factor#PC00246 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>FKHR#P00898;Interleukin signaling pathway#P00036>FKHRL1#P00994;PI3 kinase pathway#P00048>FOXO#P01198;CCKR signaling map#P06959>FOXO3#P07073 MONDO|Ensembl=ENSMODG00000005293.4|UniProtKB=F7DMN3 F7DMN3 PDLIM1 PTHR24214:SF5 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 1 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;heart development#GO:0007507;cellular process#GO:0009987;organelle organization#GO:0006996;system development#GO:0048731;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;circulatory system development#GO:0072359;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;actomyosin#GO:0042641;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;cell-cell junction#GO:0005911;adherens junction#GO:0005912;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cell junction#GO:0030054;actin filament#GO:0005884;I band#GO:0031674;cytoskeleton#GO:0005856;stress fiber#GO:0001725;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512;actin filament bundle#GO:0032432;myofibril#GO:0030016;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000009212.4|UniProtKB=F6YZ52 F6YZ52 GRB10 PTHR11243:SF4 GROWTH FACTOR RECEPTOR-BOUND PROTEIN GROWTH FACTOR RECEPTOR-BOUND PROTEIN 10 binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor complex adaptor activity#GO:0030159;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;protein binding#GO:0005515 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to peptide hormone#GO:0043434;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;negative regulation of signal transduction#GO:0009968 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019387.5|UniProtKB=F7DXF2 F7DXF2 MEX3B PTHR23285:SF5 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING PROTEIN MEX3B RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000020916.4|UniProtKB=A0A5F8G3Q6 A0A5F8G3Q6 PTHR24356:SF170 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C ZETA TYPE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 protein localization to cell periphery#GO:1990778;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;cellular response to insulin stimulus#GO:0032869;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;cellular response to nitrogen compound#GO:1901699;localization within membrane#GO:0051668;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;localization#GO:0051179;establishment of cell polarity#GO:0030010;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;protein localization to plasma membrane#GO:0072659;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167 Endothelin signaling pathway#P00019>PKC#P00568;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKCzeta#P00829;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKC#P00861;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109 MONDO|Ensembl=ENSMODG00000025426.2|UniProtKB=F6W3C1 F6W3C1 MACIR PTHR31224:SF2 UNC119-BINDING PROTEIN C5ORF30 MACROPHAGE IMMUNOMETABOLISM REGULATOR regulation of cell motility#GO:2000145;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell migration#GO:0030334;negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of locomotion#GO:0040012;regulation of multicellular organismal process#GO:0051239 MONDO|Ensembl=ENSMODG00000050123.1|UniProtKB=A0A5F8G7H6 A0A5F8G7H6 PTHR20515:SF0 BETA-DEFENSIN BETA-DEFENSIN 103 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488 response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;locomotion#GO:0040011;response to stimulus#GO:0050896;cell motility#GO:0048870;cellular response to stimulus#GO:0051716;cell chemotaxis#GO:0060326;defense response to bacterium#GO:0042742;chemotaxis#GO:0006935;cellular response to chemical stimulus#GO:0070887;response to bacterium#GO:0009617;response to other organism#GO:0051707;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000014078.4|UniProtKB=F6R519 F6R519 KLHL18 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000008985.3|UniProtKB=F7BQE3 F7BQE3 DNAJC3 PTHR44140:SF3 LD25575P DNAJ HOMOLOG SUBFAMILY C MEMBER 3 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000016381.4|UniProtKB=A0A5F8GMD2 A0A5F8GMD2 ATP9A PTHR24092:SF49 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IIA-RELATED transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;intramembrane lipid carrier activity#GO:0140303 cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;endocytosis#GO:0006897;lipid translocation#GO:0034204;lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008;macromolecule localization#GO:0033036;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;lipid transport#GO:0006869;vesicle-mediated transport#GO:0016192;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;regulation of membrane lipid distribution#GO:0097035 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;plasma membrane#GO:0005886;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;Golgi apparatus#GO:0005794 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000025317.3|UniProtKB=F7END4 F7END4 PTHR28601:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 24 COILED-COIL DOMAIN-CONTAINING PROTEIN 24 MONDO|Ensembl=ENSMODG00000012170.4|UniProtKB=F7CY98 F7CY98 HECW2 PTHR11254:SF127 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HECW2 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;regulation of dendrite morphogenesis#GO:0048814;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;regulation of developmental process#GO:0050793;regulation of cell projection organization#GO:0031344;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of plasma membrane bounded cell projection organization#GO:0120035;macromolecule metabolic process#GO:0043170;regulation of anatomical structure morphogenesis#GO:0022603;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000025724.3|UniProtKB=F6T2K4 F6T2K4 LOC103104062 PTHR10671:SF42 EPITHELIAL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 202 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000027879.2|UniProtKB=A0A5F8HFE8 A0A5F8HFE8 LOC103093910 PTHR24377:SF1028 IP01015P-RELATED ZINC FINGER PROTEIN 84 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006074.3|UniProtKB=F7FET1 F7FET1 LOC100017162 PTHR26453:SF214 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2AJ1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018392.4|UniProtKB=A0A5F8HE22 A0A5F8HE22 LRCH3 PTHR16083:SF7 LEUCINE RICH REPEAT CONTAINING PROTEIN DISP COMPLEX PROTEIN LRCH3 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007358.4|UniProtKB=F7ADR4 F7ADR4 LOC100024923 PTHR10271:SF28 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 5 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to virus#GO:0051607;antiviral innate immune response#GO:0140374;cellular response to cytokine stimulus#GO:0071345;response to virus#GO:0009615;response to peptide#GO:1901652;immune system process#GO:0002376;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to other organism#GO:0051707;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000008305.4|UniProtKB=A0A5F8G360 A0A5F8G360 CLINT1 PTHR12276:SF126 EPSIN/ENT-RELATED CLATHRIN INTERACTOR 1 phospholipid binding#GO:0005543;binding#GO:0005488;clathrin binding#GO:0030276;protein binding#GO:0005515;lipid binding#GO:0008289 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle coat#GO:0030120;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;clathrin-coated vesicle membrane#GO:0030665;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle#GO:0030136;clathrin vesicle coat#GO:0030125;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000028015.2|UniProtKB=K7E2A6 K7E2A6 PTHR11467:SF176 HISTONE H1 HISTONE H1.1 chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;chromatin DNA binding#GO:0031490 regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of DNA recombination#GO:0045910;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;chromosome condensation#GO:0030261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA recombination#GO:0000018 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000040451.1|UniProtKB=A0A5F8HJ74 A0A5F8HJ74 LOC100013918 PTHR26450:SF422 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012158.3|UniProtKB=F7CYQ7 F7CYQ7 NODAL PTHR11848:SF159 TGF-BETA FAMILY NODAL HOMOLOG molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;activin receptor signaling pathway#GO:0032924;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cellular developmental process#GO:0048869 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000049956.1|UniProtKB=A0A5F8HHS6 A0A5F8HHS6 CENPA PTHR11426:SF191 HISTONE H3 HISTONE H3-LIKE CENTROMERIC PROTEIN A mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic metaphase chromosome alignment#GO:0007080;protein-containing complex assembly#GO:0065003;mitotic cell cycle#GO:0000278;nuclear division#GO:0000280;organelle localization#GO:0051640;organelle assembly#GO:0070925;kinetochore assembly#GO:0051382;organelle fission#GO:0048285;localization#GO:0051179;kinetochore organization#GO:0051383 chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 MONDO|Ensembl=ENSMODG00000039082.1|UniProtKB=A0A5F8G7X8 A0A5F8G7X8 LOC103097840 PTHR39299:SF1 TRANSMEMBRANE PROTEIN DUF7789 DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000013304.4|UniProtKB=A0A5F8H7R5 A0A5F8H7R5 PTHR24376:SF245 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 585A zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000016823.4|UniProtKB=F7FIF6 F7FIF6 PTHR24023:SF866 COLLAGEN ALPHA COLLAGEN ALPHA-3(IX) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;interstitial matrix#GO:0005614 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000024697.3|UniProtKB=F7B2D5 F7B2D5 TICRR PTHR21556:SF2 TRESLIN TRESLIN chromatin binding#GO:0003682;binding#GO:0005488 DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;regulation of cell cycle process#GO:0010564;regulation of DNA-templated DNA replication initiation#GO:0030174;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of DNA replication#GO:0006275;cellular response to stress#GO:0033554;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;mitotic DNA replication checkpoint signaling#GO:0033314;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA damage checkpoint signaling#GO:0000077;mitotic G2/M transition checkpoint#GO:0044818;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA integrity checkpoint signaling#GO:0031570;regulation of primary metabolic process#GO:0080090;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of metabolic process#GO:0019222;intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;mitotic DNA damage checkpoint signaling#GO:0044773;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;regulation of DNA-templated DNA replication#GO:0090329;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000002955.2|UniProtKB=F6PJU2 F6PJU2 PTHR21237:SF25 GRPE PROTEIN GRPE PROTEIN HOMOLOG 1, MITOCHONDRIAL enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein localization to mitochondrion#GO:0070585;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;protein transport#GO:0015031 membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;organelle lumen#GO:0043233;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000037521.1|UniProtKB=F7B9H6 F7B9H6 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002162.3|UniProtKB=F6YET9 F6YET9 NFYB PTHR11064:SF9 CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 MONDO|Ensembl=ENSMODG00000001282.4|UniProtKB=A0A5F8G682 A0A5F8G682 KCND3 PTHR11537:SF182 VOLTAGE-GATED POTASSIUM CHANNEL A-TYPE VOLTAGE-GATED POTASSIUM CHANNEL KCND3 transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079 cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;action potential#GO:0001508;export from cell#GO:0140352;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811 transmembrane transporter complex#GO:1902495;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;dendritic tree#GO:0097447;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cell body#GO:0044297;dendritic spine#GO:0043197;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;transporter complex#GO:1990351;cation channel complex#GO:0034703;synaptic membrane#GO:0097060;voltage-gated potassium channel complex#GO:0008076;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 voltage-gated ion channel#PC00241;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000036964.1|UniProtKB=A0A5F8H8M1 A0A5F8H8M1 CAMLG PTHR15026:SF0 CALCIUM-SIGNAL MODULATING CYCLOPHILIN LIGAND CAML GUIDED ENTRY OF TAIL-ANCHORED PROTEINS FACTOR CAMLG membrane organization#GO:0061024;endomembrane system organization#GO:0010256;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000018680.5|UniProtKB=A0A5F8GWV7 A0A5F8GWV7 IWS1 PTHR46010:SF1 PROTEIN IWS1 HOMOLOG PROTEIN IWS1 HOMOLOG transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;localization#GO:0051179;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000049030.1|UniProtKB=F7EEM6 F7EEM6 LOC100013748 PTHR23428:SF374 HISTONE H2B HISTONE H2B TYPE 1-B defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to other organism#GO:0051707;defense response to other organism#GO:0098542 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000011244.4|UniProtKB=F7CI40 F7CI40 NAPRT PTHR11098:SF1 NICOTINATE PHOSPHORIBOSYLTRANSFERASE NICOTINATE PHOSPHORIBOSYLTRANSFERASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;pyridine-containing compound metabolic process#GO:0072524;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000005797.4|UniProtKB=F6XFE8 F6XFE8 TMEM114 PTHR20516:SF2 TRANSMEMBRANE PROTEIN 114/235 FAMILY MEMBER TRANSMEMBRANE PROTEIN 114 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000007187.3|UniProtKB=F6XAJ9 F6XAJ9 NT5C PTHR16504:SF5 5'(3')-DEOXYRIBONUCLEOTIDASE 5'(3')-DEOXYRIBONUCLEOTIDASE, CYTOSOLIC TYPE 5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139 MONDO|Ensembl=ENSMODG00000006102.4|UniProtKB=A0A5F8H211 A0A5F8H211 SMG1 PTHR11139:SF71 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE_THREONINE-PROTEIN KINASE SMG1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;cellular response to stress#GO:0033554;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular process#GO:0009987;response to stress#GO:0006950;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000019060.3|UniProtKB=H9H792 H9H792 PTHR11525:SF23 FARNESYL-PYROPHOSPHATE SYNTHETASE FARNESYL PYROPHOSPHATE SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;terpenoid biosynthetic process#GO:0016114;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;metabolic process#GO:0008152;terpenoid metabolic process#GO:0006721;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;organophosphate biosynthetic process#GO:0090407;isoprenoid metabolic process#GO:0006720 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739 transferase#PC00220;acyltransferase#PC00042 Cholesterol biosynthesis#P00014>Geranyl trans-transferase#P00493 MONDO|Ensembl=ENSMODG00000012130.3|UniProtKB=A0A5F8HCK3 A0A5F8HCK3 PTHR15453:SF8 TUMOR SUPPRESSOR CANDIDATE 2 TUMOR SUPPRESSOR CANDIDATE 2 response to stimulus#GO:0050896;regulation of membrane potential#GO:0042391;biological regulation#GO:0065007;defense response#GO:0006952;regulation of biological quality#GO:0065008;response to stress#GO:0006950;inflammatory response#GO:0006954 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000010321.4|UniProtKB=F6S9Y2 F6S9Y2 TRMT2A PTHR45904:SF2 TRNA (URACIL-5-)-METHYLTRANSFERASE TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG A RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000039530.1|UniProtKB=A0A5F8GWL9 A0A5F8GWL9 PTHR11738:SF199 MHC CLASS I NK CELL RECEPTOR IG-LIKE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000015681.4|UniProtKB=A0A5F8H4U2 A0A5F8H4U2 DHX37 PTHR18934:SF99 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX37-RELATED RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000016120.4|UniProtKB=F7EAK9 F7EAK9 MYNN PTHR23226:SF170 ZINC FINGER AND SCAN DOMAIN-CONTAINING MYONEURIN transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015545.5|UniProtKB=F6SKM7 F6SKM7 WDR43 PTHR44267:SF1 WD REPEAT-CONTAINING PROTEIN 43 WD REPEAT-CONTAINING PROTEIN 43 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000009613.4|UniProtKB=A0A5F8G323 A0A5F8G323 GTPBP1 PTHR43721:SF9 ELONGATION FACTOR TU-RELATED GTP-BINDING PROTEIN 1 translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 translation elongation factor#PC00222 MONDO|Ensembl=ENSMODG00000000249.3|UniProtKB=A0A5F8GWG3 A0A5F8GWG3 RMDN3 PTHR16056:SF18 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 3 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;spindle pole#GO:0000922;mitochondrion#GO:0005739;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;mitotic spindle pole#GO:0097431;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;spindle#GO:0005819 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000023872.2|UniProtKB=A0A5F8H885 A0A5F8H885 YTHDF2 PTHR12357:SF8 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN 2 protein-RNA adaptor activity#GO:0140517;nucleic acid binding#GO:0003676;binding#GO:0005488;molecular adaptor activity#GO:0060090;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;RNA binding#GO:0003723 regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;positive regulation of mRNA catabolic process#GO:0061014;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;positive regulation of macromolecule metabolic process#GO:0010604;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000005356.4|UniProtKB=K7E2U8 K7E2U8 STK11 PTHR43895:SF181 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE STK11 protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;kinase activity#GO:0016301;transferase activity#GO:0016740;enzyme activator activity#GO:0008047;protein kinase activity#GO:0004672;molecular function activator activity#GO:0140677;phosphotransferase activity, alcohol group as acceptor#GO:0016773;enzyme regulator activity#GO:0030234;protein serine/threonine kinase activity#GO:0004674;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein kinase activator activity#GO:0030295;catalytic activity#GO:0003824;kinase activator activity#GO:0019209 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 p53 pathway by glucose deprivation#P04397>LKB1#P04647 MONDO|Ensembl=ENSMODG00000001316.4|UniProtKB=F7BE06 F7BE06 ARPC1B PTHR10709:SF10 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 1B actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;cortical actin cytoskeleton organization#GO:0030866;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912;Huntington disease#P00029>Arp2/3 complex#P00811;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876 MONDO|Ensembl=ENSMODG00000006670.4|UniProtKB=A0A5F8GU90 A0A5F8GU90 MIGA2 PTHR21508:SF4 MITOGUARDIN MITOGUARDIN 2 mitochondrial fusion#GO:0008053;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;organelle fusion#GO:0048284;mitochondrion organization#GO:0007005 MONDO|Ensembl=ENSMODG00000040534.1|UniProtKB=A0A5F8HCR5 A0A5F8HCR5 PTHR24206:SF57 OS06G0237300 PROTEIN LIM DOMAIN AND ACTIN-BINDING PROTEIN 1 binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;actin filament bundle assembly#GO:0051017 organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000001742.4|UniProtKB=A0A5F8GBH3 A0A5F8GBH3 FCHO2 PTHR23065:SF8 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 F-BAR DOMAIN ONLY PROTEIN 2 cellular localization#GO:0051641;localization#GO:0051179;endocytosis#GO:0006897;clathrin-dependent endocytosis#GO:0072583;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;synaptic vesicle endocytosis#GO:0048488;protein-containing complex organization#GO:0043933;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085 vesicle#GO:0031982;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;clathrin-coated vesicle#GO:0030136 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000016953.4|UniProtKB=A0A5F8GDW8 A0A5F8GDW8 DMTF1 PTHR46380:SF2 CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1 CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000005979.4|UniProtKB=F6VZ72 F6VZ72 SDE2 PTHR12786:SF1 SPLICING FACTOR SF3A-RELATED SPLICING REGULATOR SDE2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515 RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000012746.4|UniProtKB=F6T103 F6T103 LHX9 PTHR24208:SF95 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX9 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000002661.4|UniProtKB=F7DI36 F7DI36 TIMM23B PTHR15371:SF0 TIM23 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM23 transmembrane protein transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;mitochondrial transmembrane transport#GO:1990542;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036 inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 secondary carrier transporter#PC00258;amino acid transporter#PC00046;transporter#PC00227 MONDO|Ensembl=ENSMODG00000049522.1|UniProtKB=A0A5F8G752 A0A5F8G752 PIM3 PTHR22984:SF26 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE PIM-3 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of mitotic cell cycle#GO:0007346;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000008191.4|UniProtKB=F7DJU9 F7DJU9 RNF141 PTHR12109:SF3 RING FINGER PROTEIN 141-RELATED RING FINGER PROTEIN 141 ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 MONDO|Ensembl=ENSMODG00000045528.1|UniProtKB=A0A5F8GE74 A0A5F8GE74 PTHR10075:SF138 BASIGIN RELATED PROTEIN-TYROSINE-PHOSPHATASE cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000001944.4|UniProtKB=F6VJV6 F6VJV6 KLHL38 PTHR24412:SF462 KELCH PROTEIN KELCH-LIKE PROTEIN 38 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000043220.1|UniProtKB=A0A5F8GHR6 A0A5F8GHR6 ZWINT PTHR31504:SF1 ZW10 INTERACTOR ZWINT OUTER KINETOCHORE KNL1 COMPLEX SUBUNIT ZWINT cellular component organization or biogenesis#GO:0071840;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of chromosome segregation#GO:0051985;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;signal transduction#GO:0007165;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;cellular localization#GO:0051641;nuclear division#GO:0000280;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;chromosome organization#GO:0051276;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of cellular process#GO:0050794;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;negative regulation of organelle organization#GO:0010639;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of cell cycle#GO:0045786;chromosome segregation#GO:0007059;regulation of chromosome segregation#GO:0051983;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of mitotic nuclear division#GO:0007088;establishment of localization#GO:0051234;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;regulation of mitotic cell cycle#GO:0007346;mitotic sister chromatid segregation#GO:0000070;intracellular signal transduction#GO:0035556;organelle fission#GO:0048285;localization#GO:0051179;cell communication#GO:0007154;negative regulation of chromosome organization#GO:2001251;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;negative regulation of cellular component organization#GO:0051129;mitotic cell cycle checkpoint signaling#GO:0007093 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;organelle lumen#GO:0043233;chromosome#GO:0005694;kinetochore#GO:0000776;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;dendrite#GO:0030425;intracellular organelle lumen#GO:0070013;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;nuclear body#GO:0016604;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;membrane-enclosed lumen#GO:0031974;condensed chromosome, centromeric region#GO:0000779;cytosol#GO:0005829;nucleus#GO:0005634;neuron projection#GO:0043005;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775 MONDO|Ensembl=ENSMODG00000000621.4|UniProtKB=F6TAR2 F6TAR2 CYTH4 PTHR10663:SF323 GUANYL-NUCLEOTIDE EXCHANGE FACTOR CYTOHESIN-4 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000016781.4|UniProtKB=F7G6J3 F7G6J3 IYD PTHR23026:SF128 NADPH NITROREDUCTASE IODOTYROSINE DEIODINASE 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolic process#GO:0008152;regulation of biological quality#GO:0065008;modified amino acid metabolic process#GO:0006575;phenol-containing compound metabolic process#GO:0018958;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;hormone metabolic process#GO:0042445;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;reductase#PC00198 MONDO|Ensembl=ENSMODG00000016837.4|UniProtKB=F6R217 F6R217 CCDC3 PTHR31663:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 3 COILED-COIL DOMAIN-CONTAINING PROTEIN 3 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of biological process#GO:0048519;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of gene expression#GO:0010629;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000007505.4|UniProtKB=F7GK24 F7GK24 KLHL28 PTHR24412:SF441 KELCH PROTEIN KELCH-LIKE PROTEIN 28 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020894.3|UniProtKB=H9H7Q8 H9H7Q8 PTHR21250:SF0 PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000002721.5|UniProtKB=H9H613 H9H613 INHBA PTHR11848:SF133 TGF-BETA FAMILY INHIBIN BETA A CHAIN molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>Inhba#P06723;Gonadotropin-releasing hormone receptor pathway#P06664>Inhba/b#P06700;TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000050980.1|UniProtKB=A0A5F8HAR9 A0A5F8HAR9 RAB27B PTHR47977:SF33 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-27B ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;establishment of localization#GO:0051234;regulation of localization#GO:0032879;regulation of transport#GO:0051049;exocytosis#GO:0006887;transport#GO:0006810;regulation of cellular process#GO:0050794;export from cell#GO:0140352;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;secretion#GO:0046903;localization#GO:0051179;regulation of secretion#GO:0051046;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;positive regulation of secretion#GO:0051047 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;apical plasma membrane#GO:0016324;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;Golgi apparatus#GO:0005794;apical part of cell#GO:0045177 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000017324.3|UniProtKB=F6WWK3 F6WWK3 GUCA2B PTHR11318:SF4 GUANYLIN FAMILY MEMBER GUANYLATE CYCLASE ACTIVATOR 2B enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;cyclase regulator activity#GO:0010851 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000000005.4|UniProtKB=A0A5F8GZW0 A0A5F8GZW0 PRKX PTHR24353:SF160 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cell adhesion#GO:0007155;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;GABA-B receptor II signaling#P05731>PKA#P05752;Endothelin signaling pathway#P00019>PKA#P00570;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Enkephalin release#P05913>PKA#P05972;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862 MONDO|Ensembl=ENSMODG00000009991.3|UniProtKB=F6USQ4 F6USQ4 PIGM PTHR12886:SF0 PIG-M MANNOSYLTRANSFERASE GPI ALPHA-1,4-MANNOSYLTRANSFERASE I, CATALYTIC SUBUNIT glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247;phospholipid metabolic process#GO:0006644;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mannosyltransferase complex#GO:0031501 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000018355.4|UniProtKB=F6PQG6 F6PQG6 SNX14 PTHR22775:SF44 SORTING NEXIN SORTING NEXIN-14 binding#GO:0005488;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;small molecule binding#GO:0036094;ion binding#GO:0043167 autophagosome maturation#GO:0097352;metabolic process#GO:0008152;cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;process utilizing autophagic mechanism#GO:0061919;cellular component organization#GO:0016043;cellular process#GO:0009987;autophagy#GO:0006914;catabolic process#GO:0009056;macroautophagy#GO:0016236;protein-containing complex disassembly#GO:0032984 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;late endosome#GO:0005770;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004730.4|UniProtKB=A0A5F8H0C9 A0A5F8H0C9 ETS1 PTHR11849:SF314 ETS PROTEIN C-ETS-1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 Angiogenesis#P00005>Ets#P00188;Ras Pathway#P04393>Ets#P04563;PDGF signaling pathway#P00047>Ets#P01167;VEGF signaling pathway#P00056>Ets#P01419 MONDO|Ensembl=ENSMODG00000017064.4|UniProtKB=A0A5F8HI41 A0A5F8HI41 CLDND1 PTHR14347:SF3 CLAUDIN DOMAIN-CONTAINING PROTEIN 1 CLAUDIN DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000015531.5|UniProtKB=F6VHJ5 F6VHJ5 PTHR24416:SF276 TYROSINE-PROTEIN KINASE RECEPTOR ALK TYROSINE KINASE RECEPTOR transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of neuron differentiation#GO:0045664;regulation of cell differentiation#GO:0045595;cell surface receptor signaling pathway#GO:0007166;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001523.4|UniProtKB=A0A5F8H2U2 A0A5F8H2U2 ADAMTS16 PTHR13723:SF140 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 16 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000050489.1|UniProtKB=F6QLJ0 F6QLJ0 LOC100014148 PTHR48001:SF39 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045167.1|UniProtKB=A0A5F8G993 A0A5F8G993 DYNLL2 PTHR11886:SF113 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN 2, CYTOPLASMIC microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000003784.2|UniProtKB=F7AA51 F7AA51 TRMT6 PTHR12945:SF0 TRANSLATION INITIATION FACTOR EIF3-RELATED TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT TRM6 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;methyltransferase complex#GO:0034708;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000019647.4|UniProtKB=F6UAL2 F6UAL2 PPWD1 PTHR45625:SF4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;cis-trans isomerase activity#GO:0016859;catalytic activity#GO:0003824 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000004843.4|UniProtKB=F6U5E4 F6U5E4 GADD45B PTHR10411:SF5 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 BETA protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;regulation of JNK cascade#GO:0046328;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;regulation of intracellular signal transduction#GO:1902531;positive regulation of JNK cascade#GO:0046330;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 p53 pathway#P00059>GADD45#P04626;p53 pathway#P00059>GADD45#G01575 MONDO|Ensembl=ENSMODG00000011577.4|UniProtKB=F6XX15 F6XX15 VPS29 PTHR11124:SF12 VACUOLAR SORTING PROTEIN VPS29 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 29 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;retromer complex#GO:0030904;vesicle#GO:0031982;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020 vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000024174.1|UniProtKB=F7FUU3 F7FUU3 VPS25 PTHR13149:SF0 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS25 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 25 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular localization#GO:0051641;protein transport#GO:0015031;establishment of protein localization to vacuole#GO:0072666;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;protein localization to vacuole#GO:0072665;protein metabolic process#GO:0019538;localization#GO:0051179;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein localization to organelle#GO:0033365;catabolic process#GO:0009056 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000018532.2|UniProtKB=A0A5F8GVR4 A0A5F8GVR4 PTHR10496:SF21 40S RIBOSOMAL PROTEIN S24 40S RIBOSOMAL PROTEIN S24 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000023388.3|UniProtKB=A0A5F8G4N5 A0A5F8G4N5 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000021403.3|UniProtKB=F7CVG3 F7CVG3 LOC100020165 PTHR23245:SF25 TRNA METHYLTRANSFERASE TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 2 HOMOLOG catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;methylation#GO:0032259;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000019639.4|UniProtKB=F7DDG4 F7DDG4 TRAF1 PTHR10131:SF96 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 1 binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;tumor necrosis factor receptor superfamily binding#GO:0032813 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;signal transduction#GO:0007165;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;response to tumor necrosis factor#GO:0034612;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to peptide#GO:1901652;cell communication#GO:0007154;tumor necrosis factor-mediated signaling pathway#GO:0033209;regulation of signaling#GO:0023051;cytokine-mediated signaling pathway#GO:0019221;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013740.5|UniProtKB=A0A5F8G4A2 A0A5F8G4A2 SRPK1 PTHR47634:SF4 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED SRSF PROTEIN KINASE 1 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;response to stimulus#GO:0050896;ribonucleoprotein complex biogenesis#GO:0022613;signaling#GO:0023052;mRNA metabolic process#GO:0016071;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of mRNA metabolic process#GO:1903311;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000017206.4|UniProtKB=F6XEY4 F6XEY4 SLC34A3 PTHR10010:SF35 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2C solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;phosphate transmembrane transporter activity#GO:0005315;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 transport#GO:0006810;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;establishment of localization#GO:0051234;localization#GO:0051179;cellular homeostasis#GO:0019725;inorganic anion transport#GO:0015698;intracellular chemical homeostasis#GO:0055082;phosphate ion transport#GO:0006817;homeostatic process#GO:0042592 apical plasma membrane#GO:0016324;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;brush border#GO:0005903;organelle#GO:0043226;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical part of cell#GO:0045177;membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000005214.3|UniProtKB=F7A1U3 F7A1U3 NOP16 PTHR13243:SF1 HSPC111 PROTEIN-RELATED NUCLEOLAR PROTEIN 16 cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000020459.4|UniProtKB=F7FJJ1 F7FJJ1 OSBPL8 PTHR10972:SF216 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 8 steroid binding#GO:0005496;cholesterol binding#GO:0015485;lipid binding#GO:0008289;alcohol binding#GO:0043178;sterol binding#GO:0032934;small molecule binding#GO:0036094;binding#GO:0005488 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cytosol#GO:0005829 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000016207.4|UniProtKB=F7FY23 F7FY23 ADA PTHR11409:SF53 ADENOSINE DEAMINASE ADENOSINE DEAMINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;adenosine deaminase activity#GO:0004000;catalytic activity#GO:0003824 glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;regulation of circadian rhythm#GO:0042752;carbohydrate derivative metabolic process#GO:1901135;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;small molecule biosynthetic process#GO:0044283;nucleobase metabolic process#GO:0009112;primary metabolic process#GO:0044238;leukocyte activation#GO:0045321;nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;cell activation#GO:0001775;purine nucleoside metabolic process#GO:0042278;cellular process#GO:0009987;adenosine metabolic process#GO:0046085;lymphocyte activation#GO:0046649;regulation of multicellular organismal process#GO:0051239;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;T cell activation#GO:0042110;nucleobase-containing small molecule catabolic process#GO:0034656;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;purine-containing compound biosynthetic process#GO:0072522;immune system process#GO:0002376;nucleoside catabolic process#GO:0009164 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 deaminase#PC00088 Adenine and hypoxanthine salvage pathway#P02723>Adenosine deaminase#P02811;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine deaminase#P02807 MONDO|Ensembl=ENSMODG00000013641.4|UniProtKB=F6UE19 F6UE19 AP3S1 PTHR11753:SF12 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-3 COMPLEX SUBUNIT SIGMA-1 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000002848.5|UniProtKB=A0A5F8HCX0 A0A5F8HCX0 APBA1 PTHR12345:SF14 SYNTENIN RELATED AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 1 binding#GO:0005488;peptide binding#GO:0042277 synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular process#GO:0009987;anterograde trans-synaptic signaling#GO:0098916;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 postsynapse#GO:0098794;dendritic spine#GO:0043197;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell junction#GO:0030054 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093;Alzheimer disease-amyloid secretase pathway#P00003>X11alpha#P00084 MONDO|Ensembl=ENSMODG00000006321.4|UniProtKB=H9H5W0 H9H5W0 PTHR24377:SF980 IP01015P-RELATED ZINC FINGER PROTEIN 420 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006734.4|UniProtKB=F7CX06 F7CX06 KCNC1 PTHR11537:SF87 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL KCNC1 potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;action potential#GO:0001508;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;potassium ion transport#GO:0006813;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220 cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell body#GO:0044297;postsynapse#GO:0098794;cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;postsynaptic membrane#GO:0045211;protein-containing complex#GO:0032991;presynapse#GO:0098793;neuron projection#GO:0043005;cell leading edge#GO:0031252;transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;neuron projection terminus#GO:0044306;neuronal cell body#GO:0043025;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;transmembrane transporter complex#GO:1902495;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;axon terminus#GO:0043679;voltage-gated potassium channel complex#GO:0008076;neuron projection membrane#GO:0032589 voltage-gated ion channel#PC00241;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000016048.3|UniProtKB=F6YUI1 F6YUI1 LOC100023508 PTHR26453:SF216 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2I1-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000446.4|UniProtKB=F6USZ0 F6USZ0 LRP8 PTHR24270:SF3 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 8 endocytosis#GO:0006897;central nervous system development#GO:0007417;anatomical structure development#GO:0048856;localization#GO:0051179;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;multicellular organism development#GO:0007275;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;developmental process#GO:0032502 membrane microdomain#GO:0098857;plasma membrane raft#GO:0044853;cell periphery#GO:0071944;caveola#GO:0005901;membrane#GO:0016020;membrane raft#GO:0045121;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 apolipoprotein#PC00052;transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000008086.4|UniProtKB=F6YJ34 F6YJ34 RPS6KA3 PTHR24351:SF58 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-3 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;TOR signaling#GO:0031929;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;TORC1 signaling#GO:0038202 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142;CCKR signaling map#P06959>RSK1/2#P07153;Interleukin signaling pathway#P00036>p90RSK#P00964;Ras Pathway#P04393>p90RSK#P04541;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888 MONDO|Ensembl=ENSMODG00000002141.4|UniProtKB=F6YF50 F6YF50 PTHR11860:SF82 POLYMERIC-IMMUNOGLOBULIN RECEPTOR POLYMERIC IMMUNOGLOBULIN RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000013715.4|UniProtKB=A0A5F8GAV4 A0A5F8GAV4 SLC26A8 PTHR11814:SF11 SULFATE TRANSPORTER TESTIS ANION TRANSPORTER 1 carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;chloride transmembrane transporter activity#GO:0015108;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000004627.4|UniProtKB=F6UNN8 F6UNN8 TM9SF3 PTHR10766:SF41 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 3 localization within membrane#GO:0051668;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;intracellular protein localization#GO:0008104;localization#GO:0051179;cellular localization#GO:0051641 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000005043.4|UniProtKB=F7BER2 F7BER2 MPZ PTHR13869:SF7 MYELIN P0 RELATED MYELIN PROTEIN P0 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;system development#GO:0048731;myelination#GO:0042552 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 myelin protein#PC00161 MONDO|Ensembl=ENSMODG00000017673.5|UniProtKB=F7GFY1 F7GFY1 MTCL3 PTHR15742:SF2 GIRDIN MICROTUBULE CROSS-LINKING FACTOR 3 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000011674.3|UniProtKB=F7GEF1 F7GEF1 CDS2 PTHR13773:SF4 PHOSPHATIDATE CYTIDYLYLTRANSFERASE PHOSPHATIDATE CYTIDYLYLTRANSFERASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 organelle assembly#GO:0070925;lipid droplet organization#GO:0034389;organophosphate biosynthetic process#GO:0090407;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;lipid storage#GO:0019915;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organophosphate metabolic process#GO:0019637;organelle organization#GO:0006996;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;cellular component assembly#GO:0022607;lipid biosynthetic process#GO:0008610 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 transferase#PC00220 MONDO|Ensembl=ENSMODG00000015769.3|UniProtKB=F6ZSC2 F6ZSC2 KCNK3 PTHR11003:SF138 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 3 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249 potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 Dopamine receptor mediated signaling pathway#P05912>K+ channel#P05957;5HT3 type receptor mediated signaling pathway#P04375>K+ channel#P04425;5HT4 type receptor mediated signaling pathway#P04376>K+ channel#P04426;Opioid proenkephalin pathway#P05915>K+ channel#P05990;Nicotine pharmacodynamics pathway#P06587>KCNK3/9#P06605;5HT2 type receptor mediated signaling pathway#P04374>K+ channel#P04413;Opioid proopiomelanocortin pathway#P05917>K+ channel#P06009;5HT1 type receptor mediated signaling pathway#P04373>K+ channel#P04407 MONDO|Ensembl=ENSMODG00000018847.4|UniProtKB=H9H780 H9H780 LMBR1L PTHR12625:SF2 LIPOCALIN-1 INTERACTING MEMBRANE RECEPTOR LIMR PROTEIN LMBR1L transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;signal transduction#GO:0007165;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;signaling#GO:0023052;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;localization#GO:0051179;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003655.4|UniProtKB=F7AZ94 F7AZ94 HACD4 PTHR11035:SF16 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 4 catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 dehydratase#PC00091 MONDO|Ensembl=ENSMODG00000009800.5|UniProtKB=A0A5F8GVJ5 A0A5F8GVJ5 LZTS1 PTHR19354:SF5 ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED ZIPPER PUTATIVE TUMOR SUPPRESSOR 1-RELATED regulation of signaling#GO:0023051;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of dendrite morphogenesis#GO:0048814;regulation of developmental process#GO:0050793;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular component organization#GO:0051128;regulation of dendrite development#GO:0050773;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344;regulation of synaptic plasticity#GO:0048167;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;regulation of neuron projection development#GO:0010975;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 dendrite#GO:0030425;dendritic tree#GO:0097447;cell junction#GO:0030054;postsynapse#GO:0098794;dendritic spine#GO:0043197;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;somatodendritic compartment#GO:0036477;cell projection#GO:0042995 MONDO|Ensembl=ENSMODG00000027463.2|UniProtKB=K7E0V8 K7E0V8 CCL20 PTHR12015:SF108 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 20 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000013768.4|UniProtKB=F6TWD8 F6TWD8 PTHR11515:SF11 GLYCOPROTEIN HORMONE BETA CHAIN LUTROPIN SUBUNIT BETA receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;molecular function regulator activity#GO:0098772 sex differentiation#GO:0007548;cellular process#GO:0009987;signal transduction#GO:0007165;gonad development#GO:0008406;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;reproductive structure development#GO:0048608;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;reproductive system development#GO:0061458;female gonad development#GO:0008585;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>LHbeta#G06688;Gonadotropin-releasing hormone receptor pathway#P06664>3' LHbeta#G06903;Gonadotropin-releasing hormone receptor pathway#P06664>5' LHbeta#G06889;Gonadotropin-releasing hormone receptor pathway#P06664>LHbeta#P06751 MONDO|Ensembl=ENSMODG00000001289.4|UniProtKB=F7C0A0 F7C0A0 TLDC2 PTHR23354:SF65 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED TLD DOMAIN-CONTAINING PROTEIN 2 response to stimulus#GO:0050896;response to oxidative stress#GO:0006979;response to stress#GO:0006950 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000018510.1|UniProtKB=F7B352 F7B352 ANAPC13 PTHR28672:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT 13 ANAPHASE-PROMOTING COMPLEX SUBUNIT 13 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein K11-linked ubiquitination#GO:0070979;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680 MONDO|Ensembl=ENSMODG00000023762.2|UniProtKB=F6SWX7 F6SWX7 LOC130457211 PTHR24028:SF73 CADHERIN-87A PROTOCADHERIN GAMMA-B1 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000001339.4|UniProtKB=F7FWB8 F7FWB8 DUS3L PTHR45846:SF1 TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000044548.1|UniProtKB=F6YNI3 F6YNI3 PTHR15327:SF0 MICROFIBRIL-ASSOCIATED PROTEIN MICROFIBRILLAR-ASSOCIATED PROTEIN 1 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000006203.3|UniProtKB=F6ZTN8 F6ZTN8 MATCAP1 PTHR31817:SF1 FAMILY NOT NAMED MICROTUBULE-ASSOCIATED TYROSINE CARBOXYPEPTIDASE 1 MONDO|Ensembl=ENSMODG00000002664.4|UniProtKB=F7DHX4 F7DHX4 TP53INP2 PTHR31671:SF2 DIABETES AND OBESITY REGULATED, ISOFORM G TUMOR PROTEIN P53-INDUCIBLE NUCLEAR PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713;protein-membrane adaptor activity#GO:0043495 metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;process utilizing autophagic mechanism#GO:0061919;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;macroautophagy#GO:0016236;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;organelle assembly#GO:0070925;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;vacuole organization#GO:0007033;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000006453.3|UniProtKB=F7FH09 F7FH09 RAB3D PTHR47980:SF17 LD44762P RAS-RELATED PROTEIN RAB-3D binding#GO:0005488;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;exocytosis#GO:0006887;secretion by cell#GO:0032940;transport#GO:0006810 cell junction#GO:0030054;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;secretory vesicle#GO:0099503;presynapse#GO:0098793;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;exocytic vesicle#GO:0070382;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle#GO:0008021 MONDO|Ensembl=ENSMODG00000010130.4|UniProtKB=F6WN53 F6WN53 PTHR11477:SF1 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 1 transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000003263.4|UniProtKB=F6T003 F6T003 PTHR40141:SF2 3',5'-CYCLIC-AMP PHOSPHODIESTERASE-RELATED 3',5'-CYCLIC-AMP PHOSPHODIESTERASE MONDO|Ensembl=ENSMODG00000017181.4|UniProtKB=A0A5F8G995 A0A5F8G995 GRIN1 PTHR18966:SF377 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 1 carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of membrane potential#GO:0042391;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of biological quality#GO:0065008;glutamate receptor signaling pathway#GO:0007215;trans-synaptic signaling#GO:0099537 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;transmembrane transporter complex#GO:1902495 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NR1#P01010 MONDO|Ensembl=ENSMODG00000009854.4|UniProtKB=F7EF78 F7EF78 PJVK PTHR16399:SF10 GASDERMIN PEJVAKIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transporter#PC00227 MONDO|Ensembl=ENSMODG00000008018.4|UniProtKB=F7CL07 F7CL07 RUVBL1 PTHR11093:SF6 RUVB-RELATED REPTIN AND PONTIN RUVB-LIKE 1 macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;cellular component biogenesis#GO:0044085;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;protein-RNA complex organization#GO:0071826;chromatin remodeling#GO:0006338;ribonucleoprotein complex biogenesis#GO:0022613;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;protein-RNA complex assembly#GO:0022618;regulation of DNA-templated transcription#GO:0006355 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000012621.2|UniProtKB=F6S2M4 F6S2M4 PTHR26453:SF95 OLFACTORY RECEPTOR OLFACTORY RECEPTOR FAMILY 10 SUBFAMILY AI MEMBER 1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019704.4|UniProtKB=F6TC65 F6TC65 SERINC5 PTHR10383:SF16 SERINE INCORPORATOR SERINE INCORPORATOR 5 membrane#GO:0016020;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000012378.3|UniProtKB=F7DHI4 F7DHI4 DIPK1C PTHR21093:SF2 DIVERGENT PROTEIN KINASE DOMAIN 1C-RELATED DIVERGENT PROTEIN KINASE DOMAIN 1C MONDO|Ensembl=ENSMODG00000012222.3|UniProtKB=F6Z725 F6Z725 PTHR12466:SF8 CDC73 DOMAIN PROTEIN PARAFIBROMIN RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023 MONDO|Ensembl=ENSMODG00000046023.1|UniProtKB=K7E4N5 K7E4N5 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000015077.3|UniProtKB=F7F3W0 F7F3W0 ABHD8 PTHR42886:SF83 RE40534P-RELATED PROTEIN ABHD8 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;transferase activity#GO:0016740 organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;phosphorus metabolic process#GO:0006793;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;homeostatic process#GO:0042592;phospholipid metabolic process#GO:0006644;organophosphate biosynthetic process#GO:0090407 MONDO|Ensembl=ENSMODG00000009009.4|UniProtKB=F7GL63 F7GL63 ITGA6 PTHR23220:SF9 INTEGRIN ALPHA INTEGRIN ALPHA-6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;immune system process#GO:0002376;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;integrin-mediated signaling pathway#GO:0007229;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;cell surface receptor signaling pathway#GO:0007166;cell migration#GO:0016477;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;signal transduction#GO:0007165 membrane#GO:0016020;membrane protein complex#GO:0098796;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;integrin complex#GO:0008305 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 MONDO|Ensembl=ENSMODG00000013695.3|UniProtKB=F6QNZ2 F6QNZ2 PTHR16451:SF11 MITOCHONDRIAL DYNAMICS PROTEINS 49/51 FAMILY MEMBER MITOCHONDRIAL DYNAMICS PROTEIN MID49 regulation of mitochondrial fission#GO:0090140;biological regulation#GO:0065007;positive regulation of mitochondrial fission#GO:0090141;regulation of developmental process#GO:0050793;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;positive regulation of developmental process#GO:0051094 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 MONDO|Ensembl=ENSMODG00000007509.6|UniProtKB=A0A5F8G5C1 A0A5F8G5C1 CHD3 PTHR45623:SF9 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD3 nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;DNA binding#GO:0003677;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;pyrophosphatase activity#GO:0016462;histone binding#GO:0042393;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000020904.3|UniProtKB=H9H7R7 H9H7R7 RSAD1 PTHR13932:SF5 COPROPORPHYRINIGEN III OXIDASE RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL iron-sulfur cluster binding#GO:0051536;binding#GO:0005488;small molecule binding#GO:0036094 metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;cellular process#GO:0009987;porphyrin-containing compound metabolic process#GO:0006778;porphyrin-containing compound biosynthetic process#GO:0006779;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidase#PC00175 Heme biosynthesis#P02746>Coproporphyrinogen oxidase (oxygen independent)#P02970 MONDO|Ensembl=ENSMODG00000001160.4|UniProtKB=F7CK93 F7CK93 FBXO11 PTHR22990:SF20 F-BOX ONLY PROTEIN F-BOX ONLY PROTEIN 11 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000037325.1|UniProtKB=H9H675 H9H675 LOC107652075 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000012341.4|UniProtKB=F7E260 F7E260 HIP1R PTHR10407:SF10 HUNTINGTIN INTERACTING PROTEIN 1 HUNTINGTIN-INTERACTING PROTEIN 1-RELATED PROTEIN cytoskeletal adaptor activity#GO:0008093;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;phosphatidylinositol phosphate binding#GO:1901981;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein-containing complex binding#GO:0044877;protein-membrane adaptor activity#GO:0043495;lipid binding#GO:0008289;protein binding#GO:0005515 transport#GO:0006810;regulation of response to stimulus#GO:0048583;actin filament organization#GO:0007015;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;localization#GO:0051179;regulation of ERBB signaling pathway#GO:1901184;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;positive regulation of cell communication#GO:0010647;regulation of apoptotic process#GO:0042981;protein-containing complex organization#GO:0043933;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;endocytosis#GO:0006897 cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;cell periphery#GO:0071944;membraneless organelle#GO:0043228;clathrin-coated vesicle#GO:0030136;cytoskeleton#GO:0005856;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell cortex#GO:0005938;vesicle#GO:0031982;cortical cytoskeleton#GO:0030863;intracellular vesicle#GO:0097708;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 Huntington disease#P00029>Hip-12#P00763 MONDO|Ensembl=ENSMODG00000042348.1|UniProtKB=A0A5F8H6U2 A0A5F8H6U2 monDomV1R1246 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017132.4|UniProtKB=F6W9F0 F6W9F0 PTHR23226:SF302 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 20-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000012711.5|UniProtKB=F6TYH3 F6TYH3 LUC7L3 PTHR12375:SF47 RNA-BINDING PROTEIN LUC7-RELATED LUC7-LIKE PROTEIN 3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003 small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000005456.3|UniProtKB=F7CGR3 F7CGR3 SERPINB2 PTHR11461:SF61 SERINE PROTEASE INHIBITOR, SERPIN PLASMINOGEN ACTIVATOR INHIBITOR 2 enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Plasminogen activating cascade#P00050>PAI-2#P01244;CCKR signaling map#P06959>PAI2#G06977;CCKR signaling map#P06959>PAI2#G07270;Blood coagulation#P00011>PAI-2#P00409 MONDO|Ensembl=ENSMODG00000017091.3|UniProtKB=F6V3X3 F6V3X3 CDK1 PTHR24056:SF334 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;histone modifying activity#GO:0140993;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;G2/M transition of mitotic cell cycle#GO:0000086;cell cycle phase transition#GO:0044770;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic cell cycle process#GO:1903047;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;mitotic G2/M transition checkpoint#GO:0044818;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;regulation of mitotic cell cycle phase transition#GO:1901990;cellular response to stress#GO:0033554;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;signal transduction#GO:0007165;cell cycle G2/M phase transition#GO:0044839;cellular process#GO:0009987;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;nucleus#GO:0005634;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>Cdc2#P04634 MONDO|Ensembl=ENSMODG00000047605.1|UniProtKB=H9H830 H9H830 PTHR48018:SF157 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009373.3|UniProtKB=F7CQ20 F7CQ20 TGDS PTHR43000:SF54 DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED UDP-D-GLUCOSE 4,6-DEHYDRATASE carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 dehydratase#PC00091 O-antigen biosynthesis#P02757>dTDP-glucose 4,6-dehydratase#P03045 MONDO|Ensembl=ENSMODG00000018493.3|UniProtKB=F7BRN2 F7BRN2 SRPRB PTHR11485:SF34 TRANSFERRIN SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT BETA protein targeting#GO:0006605;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;protein targeting to ER#GO:0045047;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization#GO:0045184 endoplasmic reticulum protein-containing complex#GO:0140534;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum#GO:0005791;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000010812.4|UniProtKB=F7BZN6 F7BZN6 GLB1 PTHR23421:SF172 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996 lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;lysosome#GO:0005764 galactosidase#PC00104;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000015123.4|UniProtKB=F7DJK4 F7DJK4 PLAAT1 PTHR13943:SF37 HRAS-LIKE SUPPRESSOR - RELATED PHOSPHOLIPASE A AND ACYLTRANSFERASE 1 A2-type glycerophospholipase activity#GO:0004623;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;carboxylic ester hydrolase activity#GO:0052689 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000042150.1|UniProtKB=A0A5F8HEH6 A0A5F8HEH6 BET1 PTHR12791:SF64 GOLGI SNARE BET1-RELATED BET1 HOMOLOG SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;Golgi organization#GO:0007030;cellular component organization#GO:0016043;vesicle fusion#GO:0006906 membrane#GO:0016020;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 MONDO|Ensembl=ENSMODG00000047247.1|UniProtKB=A0A5F8G842 A0A5F8G842 LOC100030007 PTHR15710:SF243 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF181 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000007311.5|UniProtKB=F7EY18 F7EY18 ARX PTHR24329:SF583 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN ARX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 system development#GO:0048731;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neuron differentiation#GO:0030182;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000041391.1|UniProtKB=A0A5F8G1V4 A0A5F8G1V4 PTHR45935:SF15 PROTEIN ZBED8-RELATED SCAN DOMAIN-CONTAINING PROTEIN 3 MONDO|Ensembl=ENSMODG00000018814.4|UniProtKB=F6YZC2 F6YZC2 ARNT PTHR23042:SF50 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;signaling receptor complex#GO:0043235;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 Hypoxia response via HIF activation#P00030>HIF-1beta#P00820 MONDO|Ensembl=ENSMODG00000050935.1|UniProtKB=A0A5F8GMF7 A0A5F8GMF7 PTHR11387:SF12 CYTOCHROME C OXIDASE SUBUNIT 6B CYTOCHROME C OXIDASE SUBUNIT 6B2 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxidase#PC00175 MONDO|Ensembl=ENSMODG00000004536.4|UniProtKB=A0A5F8HFH9 A0A5F8HFH9 PTHR32222:SF1 CENTROMERE PROTEIN U CENTROMERE PROTEIN U nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000015370.3|UniProtKB=F6WHI3 F6WHI3 HYAL4 PTHR11769:SF7 HYALURONIDASE HYALURONIDASE-4 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 glycosaminoglycan metabolic process#GO:0030203;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;glycosaminoglycan catabolic process#GO:0006027;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000000818.4|UniProtKB=F6S9D1 F6S9D1 TRIP13 PTHR45991:SF1 PACHYTENE CHECKPOINT PROTEIN 2 PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG DNA recombination#GO:0006310;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;meiosis I#GO:0007127;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;regulation of reproductive process#GO:2000241;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organelle fission#GO:0048285;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of organelle organization#GO:0010639;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of cellular component organization#GO:0051129;reproductive process#GO:0022414;homologous recombination#GO:0035825;regulation of cellular process#GO:0050794 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000023162.2|UniProtKB=F7FZS6 F7FZS6 EGR3 PTHR23235:SF78 KRUEPPEL-LIKE TRANSCRIPTION FACTOR EARLY GROWTH RESPONSE PROTEIN 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000007801.4|UniProtKB=F6ZIQ5 F6ZIQ5 B3GAT3 PTHR10896:SF73 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 3 hexosyltransferase activity#GO:0016758;glucuronosyltransferase activity#GO:0015020;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan metabolic process#GO:0050654;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000001876.4|UniProtKB=A0A5F8GFW5 A0A5F8GFW5 GSTM3 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 transferase#PC00220 MONDO|Ensembl=ENSMODG00000049432.1|UniProtKB=A0A5F8G1Y0 A0A5F8G1Y0 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000002448.4|UniProtKB=A0A5F8H7S6 A0A5F8H7S6 DDX39A PTHR47958:SF10 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX39A catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;mRNA transport#GO:0051028;RNA biosynthetic process#GO:0032774;establishment of RNA localization#GO:0051236;RNA splicing, via transesterification reactions#GO:0000375;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;nucleic acid transport#GO:0050657;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nuclear transport#GO:0051169;nuclear export#GO:0051168;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000020570.4|UniProtKB=A0A5F8H435 A0A5F8H435 LIMCH1 PTHR15551:SF3 LIM DOMAIN ONLY 7 LIM AND CALPONIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;binding#GO:0005488;protein binding#GO:0005515 regulation of actin filament-based process#GO:0032970;positive regulation of actin filament bundle assembly#GO:0032233;regulation of actin filament organization#GO:0110053;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of cell adhesion#GO:0030155;positive regulation of cellular component biogenesis#GO:0044089;regulation of cell junction assembly#GO:1901888;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;regulation of cell-matrix adhesion#GO:0001952;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of actin filament bundle assembly#GO:0032231;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actomyosin#GO:0042641;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin filament bundle#GO:0032432;intracellular organelle#GO:0043229;stress fiber#GO:0001725;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000006945.3|UniProtKB=F6RG35 F6RG35 RPS3 PTHR11760:SF76 30S/40S RIBOSOMAL PROTEIN S3 SMALL RIBOSOMAL SUBUNIT PROTEIN US3 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of programmed cell death#GO:0043067;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosol#GO:0005829;nucleus#GO:0005634;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000024544.1|UniProtKB=F6WZ98 F6WZ98 LOC100030238 PTHR10351:SF28 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000013087.3|UniProtKB=F7EXR1 F7EXR1 NOD2 PTHR24106:SF64 NACHT, LRR AND CARD DOMAINS-CONTAINING NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-CONTAINING PROTEIN 2 molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187 regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;defense response to bacterium#GO:0042742;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101;immune response-activating signaling pathway#GO:0002757;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of response to external stimulus#GO:0032103;positive regulation of signal transduction#GO:0009967;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;response to bacterium#GO:0009617;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;activation of innate immune response#GO:0002218;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005056.4|UniProtKB=F7AT26 F7AT26 MYO16 PTHR47335:SF1 UNCONVENTIONAL MYOSIN-XVI UNCONVENTIONAL MYOSIN-XVI anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;myosin complex#GO:0016459;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;actin cytoskeleton#GO:0015629;organelle lumen#GO:0043233 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000001934.4|UniProtKB=A0A5F8H821 A0A5F8H821 MYO9A PTHR46184:SF3 UNCONVENTIONAL MYOSIN-IXB-LIKE PROTEIN UNCONVENTIONAL MYOSIN-IXA polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;ATP-dependent activity#GO:0140657;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 cell differentiation#GO:0030154;establishment of cell polarity#GO:0030010;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;tissue morphogenesis#GO:0048729;establishment or maintenance of bipolar cell polarity#GO:0061245;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment or maintenance of cell polarity#GO:0007163;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;cellular process#GO:0009987;morphogenesis of an epithelium#GO:0002009;cellular developmental process#GO:0048869;developmental process#GO:0032502 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;actin filament#GO:0005884;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;neuron projection#GO:0043005;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;intracellular organelle#GO:0043229;axon#GO:0030424;axonal growth cone#GO:0044295;growth cone#GO:0030426;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;actin cytoskeleton#GO:0015629 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000050406.1|UniProtKB=A0A5F8HKC5 A0A5F8HKC5 LOC100020427 PTHR48002:SF45 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004783.4|UniProtKB=F6WK38 F6WK38 KCNJ5 PTHR11767:SF52 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 4 channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215 monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741 MONDO|Ensembl=ENSMODG00000007471.4|UniProtKB=F7DAC9 F7DAC9 PTHR11242:SF3 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED AH RECEPTOR-INTERACTING PROTEIN protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 cellular anatomical structure#GO:0110165;membrane#GO:0016020 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000025436.1|UniProtKB=F6VLC7 F6VLC7 NFIL3 PTHR15284:SF1 NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;rhythmic process#GO:0048511;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;circadian rhythm#GO:0007623;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;basic leucine zipper transcription factor#PC00056 MONDO|Ensembl=ENSMODG00000003141.5|UniProtKB=F6WUL0 F6WUL0 UTP20 PTHR17695:SF11 SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490 90S preribosome#GO:0030686;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000004202.4|UniProtKB=A0A5F8HGH4 A0A5F8HGH4 SERPINC1 PTHR11461:SF53 SERINE PROTEASE INHIBITOR, SERPIN ANTITHROMBIN-III extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 Blood coagulation#P00011>ATIII#P00440 MONDO|Ensembl=ENSMODG00000015913.4|UniProtKB=F6ZRQ0 F6ZRQ0 SCLY PTHR11601:SF62 CYSTEINE DESULFURYLASE FAMILY MEMBER SELENOCYSTEINE LYASE metabolite interconversion enzyme#PC00262;lyase#PC00144 MONDO|Ensembl=ENSMODG00000024105.1|UniProtKB=F6X0M1 F6X0M1 ARL11 PTHR11711:SF172 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 11 carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein#PC00020 MONDO|Ensembl=ENSMODG00000041643.1|UniProtKB=A0A5F8HB41 A0A5F8HB41 LOC100617932 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018010.4|UniProtKB=F7AKL1 F7AKL1 OSTM1 PTHR15644:SF2 OSTEOPETROSIS ASSOCIATED TRANSMEMBRANE PROTEIN 1 OSTEOPETROSIS ASSOCIATED TRANSMEMBRANE PROTEIN 1 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000008646.4|UniProtKB=F6PGG3 F6PGG3 SIX4 PTHR10390:SF36 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000036491.1|UniProtKB=A0A5F8GX83 A0A5F8GX83 PTHR21462:SF2 CELL SURFACE GLYCOPROTEIN OX2 RECEPTOR PRECURSOR CD200 RECEPTOR 1A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;side of membrane#GO:0098552 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003674.5|UniProtKB=A0A5F8GHC3 A0A5F8GHC3 UBAP2 PTHR16308:SF19 UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER UBIQUITIN-ASSOCIATED PROTEIN 2 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000007817.3|UniProtKB=A0A5F8HE64 A0A5F8HE64 UBAC2 PTHR43066:SF28 RHOMBOID-RELATED PROTEIN UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 2 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000009175.4|UniProtKB=F7ADE2 F7ADE2 IKBKG PTHR31553:SF3 NF-KAPPA-B ESSENTIAL MODULATOR NF-KAPPA-B ESSENTIAL MODULATOR protein binding#GO:0005515;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;modification-dependent protein binding#GO:0140030 positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of canonical NF-kappaB signal transduction#GO:0043123 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000000260.4|UniProtKB=F7AHC3 F7AHC3 IZUMO1R PTHR10517:SF14 FOLATE RECEPTOR FOLATE RECEPTOR 1-RELATED cargo receptor activity#GO:0038024;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 vitamin transport#GO:0051180;dicarboxylic acid transport#GO:0006835;nitrogen compound transport#GO:0071705;localization#GO:0051179;establishment of localization#GO:0051234;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000003516.3|UniProtKB=F7C814 F7C814 PTHR48018:SF14 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8B4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045765.1|UniProtKB=A0A5F8HBI6 A0A5F8HBI6 PTHR24134:SF25 ANKYRIN REPEAT-CONTAINING PROTEIN DDB_G0279043 CYCLIN-DEPENDENT KINASE 4 INHIBITOR C-RELATED p53 pathway#P00059>ARF#P01482;p53 pathway#P00059>ARF#G01574 MONDO|Ensembl=ENSMODG00000023241.2|UniProtKB=F6UCS8 F6UCS8 LAMTOR5 PTHR13342:SF2 RAGULATOR COMPLEX PROTEIN LAMTOR5 RAGULATOR COMPLEX PROTEIN LAMTOR5 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of TORC1 signaling#GO:1903432;positive regulation of TORC1 signaling#GO:1904263;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;response to acid chemical#GO:0001101;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;membrane#GO:0016020;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000041266.1|UniProtKB=A0A5F8GRL2 A0A5F8GRL2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000002814.4|UniProtKB=F7EJD0 F7EJD0 NTNG1 PTHR10574:SF28 NETRIN/LAMININ-RELATED NETRIN-G1 plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;axon development#GO:0061564;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;tissue development#GO:0009888;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030 extracellular matrix protein#PC00102 Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344;Axon guidance mediated by netrin#P00009>Netrin#P00357 MONDO|Ensembl=ENSMODG00000045925.1|UniProtKB=A0A5F8H7P2 A0A5F8H7P2 PTHR12768:SF4 BECLIN 1 BECLIN-1 protein binding#GO:0005515;phosphatidylinositol 3-kinase binding#GO:0043548;binding#GO:0005488;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 response to nutrient levels#GO:0031667;macroautophagy#GO:0016236;transport#GO:0006810;vacuolar transport#GO:0007034;cellular response to nutrient levels#GO:0031669;autophagy of mitochondrion#GO:0000422;intracellular transport#GO:0046907;cellular response to starvation#GO:0009267;establishment of localization#GO:0051234;mitophagy#GO:0000423;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;catabolic process#GO:0009056;organelle assembly#GO:0070925;vacuole organization#GO:0007033;localization#GO:0051179;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;late endosome to vacuole transport#GO:0045324;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641 extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;phosphatidylinositol 3-kinase complex, class III#GO:0035032;catalytic complex#GO:1902494;transferase complex#GO:1990234;phagophore assembly site#GO:0000407;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000048666.1|UniProtKB=A0A5F8HHZ7 A0A5F8HHZ7 LOC100028477 PTHR26452:SF977 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005452.3|UniProtKB=F7CGZ6 F7CGZ6 TSTD1 PTHR45544:SF1 THIOSULFATE:GLUTATHIONE SULFURTRANSFERASE THIOSULFATE:GLUTATHIONE SULFURTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000048794.1|UniProtKB=A0A5F8GGH7 A0A5F8GGH7 SHOX2 PTHR46255:SF1 SHORT STATURE HOMEOBOX SHORT STATURE HOMEOBOX PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000009794.4|UniProtKB=F6SYY6 F6SYY6 DPF2 PTHR45888:SF7 HL01030P-RELATED ZINC FINGER PROTEIN UBI-D4 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523 SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000015706.3|UniProtKB=F7DGG3 F7DGG3 INO80E PTHR21812:SF1 INO80 COMPLEX SUBUNIT E INO80 COMPLEX SUBUNIT E regulation of DNA replication#GO:0006275;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;Ino80 complex#GO:0031011;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000036975.1|UniProtKB=A0A5F8HI66 A0A5F8HI66 LOC100012600 PTHR26453:SF115 OLFACTORY RECEPTOR OLFACTORY RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007585.4|UniProtKB=A0A5F8H2N8 A0A5F8H2N8 CNTROB PTHR34439:SF1 CENTROBIN CENTROBIN microtubule organizing center organization#GO:0031023;mitotic cell cycle process#GO:1903047;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;centriole replication#GO:0007099;cytokinetic process#GO:0032506;organelle assembly#GO:0070925;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;microtubule cytoskeleton organization#GO:0000226;mitotic cytokinetic process#GO:1902410;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell division#GO:0051301;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281 centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000011256.4|UniProtKB=F6R1W9 F6R1W9 ACTR1A PTHR11937:SF370 ACTIN ALPHA-CENTRACTIN structural molecule activity#GO:0005198;protein-membrane adaptor activity#GO:0043495;cytoskeletal adaptor activity#GO:0008093;structural constituent of cytoskeleton#GO:0005200;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 organelle localization#GO:0051640;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;nuclear migration#GO:0007097;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232 actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090 MONDO|Ensembl=ENSMODG00000001927.4|UniProtKB=F6W0S3 F6W0S3 ZBTB11 PTHR24384:SF196 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 11 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000009477.4|UniProtKB=A0A5F8GD29 A0A5F8GD29 NDST1 PTHR10605:SF30 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE 1 transferase activity#GO:0016740;deacylase activity#GO:0160215;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000009527.4|UniProtKB=F7C4E9 F7C4E9 MAP2K5 PTHR48013:SF36 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672 MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>MAP2K5#P07160 MONDO|Ensembl=ENSMODG00000012042.4|UniProtKB=A0A5F8H5M5 A0A5F8H5M5 SCAPER PTHR31434:SF2 S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM MONDO|Ensembl=ENSMODG00000037297.1|UniProtKB=A0A5F8GPL8 A0A5F8GPL8 LOC100018872 PTHR10352:SF9 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 4 negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;nervous system development#GO:0007399;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;regulation of mRNA metabolic process#GO:1903311;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;negative regulation of catabolic process#GO:0009895;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894 nucleus#GO:0005634;cell body#GO:0044297;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;perikaryon#GO:0043204;membrane-bounded organelle#GO:0043227 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000028845.2|UniProtKB=K7E309 K7E309 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000010968.4|UniProtKB=F7BC34 F7BC34 ME2 PTHR23406:SF27 MALIC ENZYME-RELATED NAD-DEPENDENT MALIC ENZYME, MITOCHONDRIAL oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000024930.2|UniProtKB=F6RAZ9 F6RAZ9 PTHR46811:SF1 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000006574.4|UniProtKB=F7B866 F7B866 HPS5 PTHR23287:SF18 RUBY-EYE2-LIKE PROTEIN BLOC-2 COMPLEX MEMBER HPS5 pigmentation#GO:0043473;developmental pigmentation#GO:0048066 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000006373.4|UniProtKB=F7GCS1 F7GCS1 PTHR22691:SF8 YEAST SPT2-RELATED PROTEIN SPT2 HOMOLOG protein binding#GO:0005515;DNA binding#GO:0003677;histone binding#GO:0042393;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription by RNA polymerase I#GO:0006360;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;chromatin organization#GO:0006325;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000047989.1|UniProtKB=K7E364 K7E364 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000004541.4|UniProtKB=A0A5F8GT53 A0A5F8GT53 PRCP PTHR11010:SF127 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED LYSOSOMAL PRO-X CARBOXYPEPTIDASE regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system development#GO:0072359;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;wound healing#GO:0042060;system development#GO:0048731;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;animal gross anatomical part developmental process#GO:0160108;regulation of locomotion#GO:0040012;tube development#GO:0035295;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;response to stress#GO:0006950;response to wounding#GO:0009611;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of cell migration#GO:0030334 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;lysosome#GO:0005764;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000025564.3|UniProtKB=F6UHU8 F6UHU8 PLET1 PTHR22527:SF2 PLACENTA-EXPRESSED TRANSCRIPT 1 PROTEIN PLACENTA-EXPRESSED TRANSCRIPT 1 PROTEIN anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;regulation of cell motility#GO:2000145;cell motility#GO:0048870;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of cell migration#GO:0030334;negative regulation of cellular process#GO:0048523;positive regulation of locomotion#GO:0040017;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;response to wounding#GO:0009611;regulation of locomotion#GO:0040012;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;cell migration#GO:0016477;regulation of cell adhesion#GO:0030155;tissue development#GO:0009888;negative regulation of cell adhesion#GO:0007162;epithelium development#GO:0060429;animal gross anatomical part developmental process#GO:0160108;wound healing#GO:0042060;regulation of cell-matrix adhesion#GO:0001952;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;negative regulation of biological process#GO:0048519;response to stimulus#GO:0050896;morphogenesis of an epithelium#GO:0002009;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to stress#GO:0006950 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;external side of plasma membrane#GO:0009897;apical part of cell#GO:0045177;side of membrane#GO:0098552 MONDO|Ensembl=ENSMODG00000015684.4|UniProtKB=F6QUL4 F6QUL4 RSRC1 PTHR31968:SF4 SERINE/ARGININE-RELATED PROTEIN 53 SERINE_ARGININE-RELATED PROTEIN 53 macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000016012.2|UniProtKB=F7EG66 F7EG66 EEF1B2 PTHR11595:SF92 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-BETA molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 translation elongation factor#PC00222 MONDO|Ensembl=ENSMODG00000011930.4|UniProtKB=A0A5F8HA54 A0A5F8HA54 TMEM150C PTHR21324:SF7 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED TRANSMEMBRANE PROTEIN 150C plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000049233.1|UniProtKB=A0A5F8GG44 A0A5F8GG44 COLEC10 PTHR24024:SF20 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A COLLECTIN-10 pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;immune system process#GO:0002376;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;defense response to symbiont#GO:0140546;complement activation#GO:0006956;immune response#GO:0006955;defense response to other organism#GO:0098542;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007;humoral immune response#GO:0006959;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 surfactant#PC00212;structural protein#PC00211 MONDO|Ensembl=ENSMODG00000009366.4|UniProtKB=A0A5F8G465 A0A5F8G465 WIPF1 PTHR10652:SF23 ADENYLYL CYCLASE-ASSOCIATED PROTEIN WAS_WASL-INTERACTING PROTEIN FAMILY MEMBER 1 binding#GO:0005488;enzyme binding#GO:0019899;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515 actin filament-based process#GO:0030029;developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000014182.4|UniProtKB=F6U6R7 F6U6R7 PTHR14949:SF53 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 VON WILLEBRAND FACTOR D AND EGF DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000047786.1|UniProtKB=A0A5F8GJL1 A0A5F8GJL1 CCDC97 PTHR31840:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 97 COILED-COIL DOMAIN-CONTAINING PROTEIN 97 MONDO|Ensembl=ENSMODG00000018854.4|UniProtKB=F7DW23 F7DW23 PIP5K1A PTHR23086:SF54 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE TYPE-1 ALPHA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772 glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 kinase#PC00137;transferase#PC00220 MONDO|Ensembl=ENSMODG00000021308.4|UniProtKB=A0A5F8GDY1 A0A5F8GDY1 ZMAT3 PTHR46786:SF1 ZINC FINGER MATRIN-TYPE PROTEIN 3 ZINC FINGER MATRIN-TYPE PROTEIN 3 RNA metabolism protein#PC00031;RNA processing factor#PC00147 p53 pathway#P00059>PAG608#G04690 MONDO|Ensembl=ENSMODG00000045645.1|UniProtKB=A0A5F8H820 A0A5F8H820 PTHR21409:SF1 HEMATOPOIETIC CELL SIGNAL TRANSDUCER HEMATOPOIETIC CELL SIGNAL TRANSDUCER protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signaling#GO:0023056 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000017265.4|UniProtKB=F6T4A1 F6T4A1 HERC4 PTHR45622:SF5 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC4-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000044087.1|UniProtKB=A0A5F8HEW7 A0A5F8HEW7 PGPEP1 PTHR23402:SF16 PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED PYROGLUTAMYL-PEPTIDASE 1 peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000004304.4|UniProtKB=F6SX19 F6SX19 SLBP PTHR17408:SF7 HISTONE RNA HAIRPIN-BINDING PROTEIN HISTONE RNA HAIRPIN-BINDING PROTEIN mRNA binding#GO:0003729;binding#GO:0005488;pre-mRNA binding#GO:0036002;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 transport#GO:0006810;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nitrogen compound transport#GO:0071705;mRNA processing#GO:0006397;macromolecule localization#GO:0033036;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;nucleic acid transport#GO:0050657;RNA metabolic process#GO:0016070;localization#GO:0051179;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;mRNA metabolic process#GO:0016071;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000001770.4|UniProtKB=F6WZ01 F6WZ01 LPCAT4 PTHR23063:SF7 PHOSPHOLIPID ACYLTRANSFERASE LYSOPHOSPHOLIPID ACYLTRANSFERASE LPCAT4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 metabolite interconversion enzyme#PC00262;transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000007807.4|UniProtKB=F7EQV3 F7EQV3 ARMH4 PTHR21585:SF0 FULL-LENGTH CDNA CLONE CS0DC025YL05 OF NEUROBLASTOMA ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 4 MONDO|Ensembl=ENSMODG00000013500.4|UniProtKB=F7F8D9 F7F8D9 CD3G PTHR10570:SF8 T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN / DELTA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cellular developmental process#GO:0048869;signal transduction#GO:0007165;cellular process#GO:0009987;hemopoiesis#GO:0030097;T cell differentiation#GO:0030217;biological regulation#GO:0065007;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;lymphocyte differentiation#GO:0030098;cell activation#GO:0001775;immune system process#GO:0002376;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;mononuclear cell differentiation#GO:1903131;leukocyte activation#GO:0045321;leukocyte differentiation#GO:0002521;T cell activation#GO:0042110;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;side of membrane#GO:0098552;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>CD3 gamma#P01317 MONDO|Ensembl=ENSMODG00000049350.1|UniProtKB=A0A5F8G2V0 A0A5F8G2V0 CCKBR PTHR24243:SF45 G-PROTEIN COUPLED RECEPTOR GASTRIN_CHOLECYSTOKININ TYPE B RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CCKR signaling map#P06959>CCK2R#P07042 MONDO|Ensembl=ENSMODG00000043147.1|UniProtKB=A0A5F8HFV7 A0A5F8HFV7 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000006208.3|UniProtKB=F6ZSS4 F6ZSS4 PTHR48001:SF124 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1M1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012826.4|UniProtKB=F7DD57 F7DD57 FAM177A1 PTHR31206:SF5 LP10445P PROTEIN FAM177A1 MONDO|Ensembl=ENSMODG00000006727.4|UniProtKB=F7CXF5 F7CXF5 UBFD1 PTHR16470:SF0 UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1 UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1 MONDO|Ensembl=ENSMODG00000012573.4|UniProtKB=F6PKT5 F6PKT5 TKT PTHR43195:SF3 TRANSKETOLASE TRANSKETOLASE transketolase activity#GO:0004802;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;heterocyclic compound binding#GO:1901363;transferase activity#GO:0016740;catalytic activity#GO:0003824;transketolase or transaldolase activity#GO:0016744 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;pentose-phosphate shunt, non-oxidative branch#GO:0009052;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt#GO:0006098;NADPH regeneration#GO:0006740;glyceraldehyde-3-phosphate metabolic process#GO:0019682;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transketolase#PC00221 Pentose phosphate pathway#P02762>Transketolase#P03082 MONDO|Ensembl=ENSMODG00000010305.4|UniProtKB=F7D2J9 F7D2J9 DBF4 PTHR15375:SF22 ACTIVATOR OF S-PHASE KINASE-RELATED PROTEIN DBF4 HOMOLOG A protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 positive regulation of metabolic process#GO:0009893;regulation of DNA replication#GO:0006275;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell cycle#GO:0051726;positive regulation of DNA metabolic process#GO:0051054;regulation of cell cycle phase transition#GO:1901987;regulation of DNA metabolic process#GO:0051052;regulation of DNA-templated DNA replication#GO:0090329;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of DNA replication#GO:0045740;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140;kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000012318.4|UniProtKB=F7EIN6 F7EIN6 MON1A PTHR13027:SF14 SAND PROTEIN-RELATED VACUOLAR FUSION PROTEIN MON1 HOMOLOG A molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;guanyl-nucleotide exchange factor activity#GO:0005085 transport#GO:0006810;secretion#GO:0046903;establishment of localization#GO:0051234;protein secretion#GO:0009306;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;protein transport#GO:0015031;secretion by cell#GO:0032940;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;protein localization to extracellular region#GO:0071692;establishment of protein localization#GO:0045184;export from cell#GO:0140352 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;late endosome#GO:0005770;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535 MONDO|Gene=AMEL|UniProtKB=Q28462 Q28462 AMEL PTHR46794:SF2 AMELOGENIN, Y ISOFORM AMELOGENIN, X ISOFORM extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 biomineral tissue development#GO:0031214;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;enamel mineralization#GO:0070166;anatomical structure formation involved in morphogenesis#GO:0048646;anatomical structure development#GO:0048856;animal organ development#GO:0048513;anatomical structure morphogenesis#GO:0009653;amelogenesis#GO:0097186;odontogenesis#GO:0042476;odontogenesis of dentin-containing tooth#GO:0042475;animal organ morphogenesis#GO:0009887;tissue development#GO:0009888 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000044048.1|UniProtKB=F6PZK0 F6PZK0 LOC100021363 PTHR26450:SF19 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000285.4|UniProtKB=F6WAV4 F6WAV4 CCN1 PTHR11348:SF18 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 1 carbohydrate derivative binding#GO:0097367;cell adhesion molecule binding#GO:0050839;heparin binding#GO:0008201;integrin binding#GO:0005178;signaling receptor binding#GO:0005102;binding#GO:0005488;glycosaminoglycan binding#GO:0005539;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of cell migration#GO:0030334;positive regulation of locomotion#GO:0040017;positive regulation of cell migration#GO:0030335;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;cell adhesion#GO:0007155;cell communication#GO:0007154;regulation of cell motility#GO:2000145;positive regulation of cell motility#GO:2000147;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;signaling#GO:0023052 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 MONDO|Ensembl=ENSMODG00000021074.3|UniProtKB=F6V188 F6V188 CFAP298 PTHR13238:SF0 PROTEIN C21ORF59 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 298 MONDO|Ensembl=ENSMODG00000012988.4|UniProtKB=A0A5F8GZF1 A0A5F8GZF1 ZNF423 PTHR24388:SF100 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 423 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000044790.1|UniProtKB=A0A5F8G3X5 A0A5F8G3X5 PTHR48001:SF105 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012603.4|UniProtKB=F6S334 F6S334 ELP1 PTHR12747:SF0 ELONGATOR COMPLEX PROTEIN 1 ELONGATOR COMPLEX PROTEIN 1 tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;elongator holoenzyme complex#GO:0033588;cytoplasm#GO:0005737;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 general transcription factor#PC00259 PDGF signaling pathway#P00047>Ikk#P01146 MONDO|Ensembl=ENSMODG00000021544.4|UniProtKB=F6WV31 F6WV31 RTN2 PTHR45799:SF3 RETICULON-LIKE PROTEIN RETICULON-2 endomembrane system organization#GO:0010256;membrane organization#GO:0061024;endoplasmic reticulum tubular network organization#GO:0071786;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum membrane organization#GO:0090158 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000013476.4|UniProtKB=F7FMG8 F7FMG8 CETP PTHR47616:SF1 CHOLESTERYL ESTER TRANSFER PROTEIN CHOLESTERYL ESTER TRANSFER PROTEIN phospholipid binding#GO:0005543;alcohol binding#GO:0043178;steroid binding#GO:0005496;phosphatidylcholine binding#GO:0031210;small molecule binding#GO:0036094;binding#GO:0005488;sterol binding#GO:0032934;ion binding#GO:0043167;cholesterol binding#GO:0015485;lipid binding#GO:0008289;cation binding#GO:0043169 lipid transport#GO:0006869;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;macromolecule localization#GO:0033036;organophosphate metabolic process#GO:0019637;neutral lipid metabolic process#GO:0006638;establishment of localization#GO:0051234;sterol metabolic process#GO:0016125;cholesterol homeostasis#GO:0042632;acylglycerol metabolic process#GO:0006639;transport#GO:0006810;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;triglyceride metabolic process#GO:0006641;homeostatic process#GO:0042592;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;localization#GO:0051179;triglyceride homeostasis#GO:0070328;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;steroid metabolic process#GO:0008202;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;chemical homeostasis#GO:0048878;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;secondary alcohol metabolic process#GO:1902652;lipid homeostasis#GO:0055088;cellular component organization#GO:0016043;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;lipid localization#GO:0010876 plasma lipoprotein particle#GO:0034358;high-density lipoprotein particle#GO:0034364;protein-lipid complex#GO:0032994;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;lipoprotein particle#GO:1990777;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 CCKR signaling map#P06959>CETP#P07189 MONDO|Ensembl=ENSMODG00000019503.4|UniProtKB=K7E3K1 K7E3K1 TTLL13 PTHR12241:SF91 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL13 catalytic activity#GO:0003824;ligase activity#GO:0016874;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000010485.4|UniProtKB=F7ESI4 F7ESI4 FUOM PTHR31690:SF4 FUCOSE MUTAROTASE FUCOSE MUTAROTASE monosaccharide binding#GO:0048029;isomerase activity#GO:0016853;carbohydrate binding#GO:0030246;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;small molecule binding#GO:0036094;binding#GO:0005488 carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318 MONDO|Ensembl=ENSMODG00000016678.4|UniProtKB=F7E6J7 F7E6J7 RAB11FIP3 PTHR15726:SF6 RAB11-FAMILY INTERACTING PROTEIN RAB11 FAMILY-INTERACTING PROTEIN 3 localization within membrane#GO:0051668;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;cellular localization#GO:0051641;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;endocytic recycling#GO:0032456;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;vesicle-mediated transport#GO:0016192 endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;midbody#GO:0030496;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;recycling endosome#GO:0055037;cleavage furrow#GO:0032154;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;cell division site#GO:0032153;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000040787.1|UniProtKB=A0A5F8H5F4 A0A5F8H5F4 PTHR23304:SF189 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000010393.4|UniProtKB=F7A7Q9 F7A7Q9 PARP10 PTHR14453:SF94 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP10 glycosyltransferase activity#GO:0016757;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;transferase activity#GO:0016740;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950 regulation of biological process#GO:0050789;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biological process#GO:0048519;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of gene expression#GO:0010629;regulation of metabolic process#GO:0019222;negative regulation of metabolic process#GO:0009892;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000008374.4|UniProtKB=A0A5F8GR37 A0A5F8GR37 PTHR24064:SF591 SOLUTE CARRIER FAMILY 22 MEMBER STEROID TRANSMEMBRANE TRANSPORTER SLC22A24 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000019351.3|UniProtKB=H9H7C1 H9H7C1 ALKBH2 PTHR31573:SF1 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 2 DNA OXIDATIVE DEMETHYLASE ALKBH2 metal ion binding#GO:0046872;binding#GO:0005488;iron ion binding#GO:0005506;demethylase activity#GO:0032451;catalytic activity, acting on DNA#GO:0140097;ferrous iron binding#GO:0008198;cation binding#GO:0043169;hydrolase activity#GO:0016787;dioxygenase activity#GO:0051213;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;ion binding#GO:0043167;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000010205.5|UniProtKB=F6SAX6 F6SAX6 EHD1 PTHR11216:SF127 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cell periphery#GO:1990778;intracellular transport#GO:0046907;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;protein localization to membrane#GO:0072657;cilium assembly#GO:0060271;protein localization to plasma membrane#GO:0072659;cellular component organization#GO:0016043;cell projection organization#GO:0030030;endocytic recycling#GO:0032456;endocytosis#GO:0006897;localization within membrane#GO:0051668;organelle assembly#GO:0070925;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641 cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;recycling endosome#GO:0055037;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000013832.4|UniProtKB=A0A5F8HEE4 A0A5F8HEE4 LSR PTHR15923:SF1 TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN LIPOLYSIS-STIMULATED LIPOPROTEIN RECEPTOR cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell-cell junction assembly#GO:0007043;nervous system development#GO:0007399;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;central nervous system development#GO:0007417;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000009006.5|UniProtKB=F6QFJ1 F6QFJ1 SLC10A3 PTHR10361:SF3 SODIUM-BILE ACID COTRANSPORTER P3 PROTEIN carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;bile acid transmembrane transporter activity#GO:0015125;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873 lipid transport#GO:0006869;macromolecule localization#GO:0033036;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;localization#GO:0051179;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;bile acid and bile salt transport#GO:0015721;lipid localization#GO:0010876 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000029481.2|UniProtKB=K7E2F9 K7E2F9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000966.4|UniProtKB=F6QHP1 F6QHP1 PTHR12066:SF0 TELOMERASE REVERSE TRANSCRIPTASE TELOMERASE REVERSE TRANSCRIPTASE telomerase activity#GO:0003720;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;RNA-directed DNA polymerase activity#GO:0003964;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;telomere maintenance via telomere lengthening#GO:0010833;telomere maintenance via telomerase#GO:0007004;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;RNA-templated DNA biosynthetic process#GO:0006278;metabolic process#GO:0008152;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleic acid biosynthetic process#GO:0141187;telomere organization#GO:0032200 intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000004307.4|UniProtKB=F6XNK0 F6XNK0 TGFB2 PTHR11848:SF141 TGF-BETA FAMILY TRANSFORMING GROWTH FACTOR BETA-2 PROPROTEIN receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 animal gross anatomical part developmental process#GO:0160108;response to transforming growth factor beta#GO:0071559;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;circulatory system development#GO:0072359;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;animal organ development#GO:0048513;transforming growth factor beta receptor signaling pathway#GO:0007179;signal transduction#GO:0007165;cellular process#GO:0009987;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286;Gonadotropin-releasing hormone receptor pathway#P06664>TGFbeta#P06778 MONDO|Ensembl=ENSMODG00000024179.2|UniProtKB=F6SJ10 F6SJ10 PTHR10836:SF111 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891;oxidoreductase activity#GO:0016491 purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nicotinamide nucleotide metabolic process#GO:0046496;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 dehydrogenase#PC00092 Huntington disease#P00029>GAPDH#P00810;Glycolysis#P00024>Glyceraldehyde 3-phosphate dehydrogenase#P00676 MONDO|Ensembl=ENSMODG00000013001.4|UniProtKB=F7C8N3 F7C8N3 USP4 PTHR21646:SF45 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 4 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;regulation of protein stability#GO:0031647;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000051449.1|UniProtKB=F6QLL6 F6QLL6 LOC100012829 PTHR48001:SF39 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006888.3|UniProtKB=F6PVQ1 F6PVQ1 TNPO2 PTHR10527:SF17 IMPORTIN BETA TRANSPORTIN-2 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein localization to organelle#GO:0033365;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nucleocytoplasmic transport#GO:0006913 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 transporter#PC00227 MONDO|Ensembl=ENSMODG00000023740.2|UniProtKB=F6WRH0 F6WRH0 GRXCR2 PTHR46926:SF1 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 2 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 2 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;system process#GO:0003008 actin cytoskeleton#GO:0015629;neuron projection#GO:0043005;actin-based cell projection#GO:0098858;microvillus#GO:0005902;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;stereocilium#GO:0032420;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000002713.4|UniProtKB=A0A5F8GW23 A0A5F8GW23 CCDC137 PTHR21838:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 137 COILED-COIL DOMAIN-CONTAINING PROTEIN 137 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000038421.1|UniProtKB=A0A5F8GML3 A0A5F8GML3 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000018753.3|UniProtKB=F7EF18 F7EF18 LIX1L PTHR31139:SF3 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG LIX1-LIKE PROTEIN organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000001427.4|UniProtKB=F7BCP7 F7BCP7 AAR2 PTHR12689:SF4 A1 CISTRON SPLICING FACTOR AAR2-RELATED PROTEIN AAR2 HOMOLOG RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000014369.4|UniProtKB=F6TNK3 F6TNK3 BCO2 PTHR10543:SF122 BETA-CAROTENE DIOXYGENASE CAROTENOID-CLEAVING DIOXYGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 catabolic process#GO:0009056;lipid catabolic process#GO:0016042;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;primary metabolic process#GO:0044238;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;olefinic compound metabolic process#GO:0120254 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000010688.4|UniProtKB=F7C0R4 F7C0R4 HPS4 PTHR14407:SF9 HERMANSKY-PUDLAK SYNDROME 4 PROTEIN LIGHT-EAR PROTEIN-RELATED BLOC-3 COMPLEX MEMBER HPS4 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 protein targeting#GO:0006605;cellular component assembly#GO:0022607;cellular pigmentation#GO:0033059;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;organelle assembly#GO:0070925;melanosome organization#GO:0032438;pigmentation#GO:0043473 intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;membrane#GO:0016020;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773 MONDO|Ensembl=ENSMODG00000043495.1|UniProtKB=K7E2B5 K7E2B5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007919.3|UniProtKB=A0A5F8G5L9 A0A5F8G5L9 LOC103102040 PTHR31980:SF1 PROTEIN FAM220A PROTEIN FAM220A nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000006806.4|UniProtKB=F6PGR8 F6PGR8 SLC22A2 PTHR24064:SF432 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 2 quaternary ammonium group transmembrane transporter activity#GO:0015651;transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 organic hydroxy compound transport#GO:0015850;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000006752.4|UniProtKB=F7CCN4 F7CCN4 NTMT1 PTHR12753:SF1 AD-003 - RELATED N-TERMINAL XAA-PRO-LYS N-METHYLTRANSFERASE 1 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity#GO:0003824;transferase activity#GO:0016740 cytoskeleton organization#GO:0007010;cellular process#GO:0009987;cell cycle process#GO:0022402;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000024782.3|UniProtKB=F7DHB7 F7DHB7 GORASP2 PTHR12893:SF1 GOLGI REASSEMBLY STACKING PROTEIN GRASP GOLGI REASSEMBLY-STACKING PROTEIN 2 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000003235.4|UniProtKB=A0A5F8G806 A0A5F8G806 AFTPH PTHR16156:SF9 AFTIPHILIN A-RELATED AFTIPHILIN binding#GO:0005488;clathrin binding#GO:0030276;protein binding#GO:0005515 protein-containing complex#GO:0032991;trans-Golgi network membrane#GO:0032588;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;vesicle coat#GO:0030120;clathrin-coated vesicle membrane#GO:0030665;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin vesicle coat#GO:0030125;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;coated membrane#GO:0048475;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982;membrane coat#GO:0030117;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;trans-Golgi network transport vesicle#GO:0030140;AP-1 adaptor complex#GO:0030121 MONDO|Ensembl=ENSMODG00000024996.2|UniProtKB=F6TU13 F6TU13 PTHR24356:SF170 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C ZETA TYPE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;response to hormone#GO:0009725;response to chemical#GO:0042221;protein localization to cell periphery#GO:1990778;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;protein localization to membrane#GO:0072657;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;macromolecule localization#GO:0033036;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;cellular response to insulin stimulus#GO:0032869;intracellular protein localization#GO:0008104;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;establishment of cell polarity#GO:0030010;protein localization to plasma membrane#GO:0072659;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;localization within membrane#GO:0051668;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;localization#GO:0051179 non-receptor serine/threonine protein kinase#PC00167 Endothelin signaling pathway#P00019>PKC#P00568;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKCzeta#P00829;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKC#P00861;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109 MONDO|Ensembl=ENSMODG00000050358.1|UniProtKB=K7E0V0 K7E0V0 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000011852.3|UniProtKB=F7GDF3 F7GDF3 ANXA4 PTHR10502:SF28 ANNEXIN ANNEXIN A4 lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;binding#GO:0005488;small molecule binding#GO:0036094;phospholipid binding#GO:0005543;anion binding#GO:0043168;ion binding#GO:0043167 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle#GO:0031982;nucleus#GO:0005634;cell periphery#GO:0071944 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000010887.4|UniProtKB=F7FJF3 F7FJF3 MYL4 PTHR23048:SF1 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 4 structural molecule activity#GO:0005198;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;actin monomer binding#GO:0003785;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;protein binding#GO:0005515;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488 multicellular organismal process#GO:0032501;blood circulation#GO:0008015;striated muscle contraction#GO:0006941;heart process#GO:0003015;muscle system process#GO:0003012;system process#GO:0003008;heart contraction#GO:0060047;circulatory system process#GO:0003013;muscle contraction#GO:0006936;cardiac muscle contraction#GO:0060048 organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;A band#GO:0031672;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;myosin complex#GO:0016459;sarcomere#GO:0030017;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000028415.2|UniProtKB=K7E1V9 K7E1V9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000019293.4|UniProtKB=A0A5F8HGJ8 A0A5F8HGJ8 ART3 PTHR10339:SF4 ADP-RIBOSYLTRANSFERASE ECTO-ADP-RIBOSYLTRANSFERASE 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 transferase#PC00220 MONDO|Ensembl=ENSMODG00000016323.3|UniProtKB=H9H6T5 H9H6T5 PTHR24098:SF14 OUTER SEGMENT 5 TRIPARTITE MOTIF-CONTAINING PROTEIN 59 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 membrane-bounded organelle#GO:0043227;intraciliary transport particle B#GO:0030992;cilium#GO:0005929;intraciliary transport particle#GO:0030990;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000000785.4|UniProtKB=F6SSD8 F6SSD8 MAP3K19 PTHR48011:SF4 CCR4-NOT TRANSCRIPTIONAL COMPLEX SUBUNIT CAF120-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000011954.4|UniProtKB=A0A5F8GVJ1 A0A5F8GVJ1 DOCK3 PTHR45653:SF4 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 3 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;enzyme binding#GO:0019899;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000020903.4|UniProtKB=H9H7R6 H9H7R6 CHAD PTHR24373:SF277 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN CHONDROADHERIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025773.2|UniProtKB=F7FT18 F7FT18 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000018249.4|UniProtKB=K7E358 K7E358 STYK1 PTHR24418:SF269 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE STYK1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;non-membrane spanning protein tyrosine kinase activity#GO:0004715;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 MONDO|Ensembl=ENSMODG00000003778.5|UniProtKB=F7AAD2 F7AAD2 MGAT4B PTHR12062:SF1 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE B hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;Golgi stack#GO:0005795 transferase#PC00220 MONDO|Ensembl=ENSMODG00000039611.1|UniProtKB=F7FQG9 F7FQG9 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000042477.1|UniProtKB=F6Q020 F6Q020 PTHR26450:SF164 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51B2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000029525.1|UniProtKB=K7E625 K7E625 PTHR10424:SF72 VIRAL ENVELOPE PROTEIN BC035947 PROTEIN-RELATED myoblast fusion#GO:0007520;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;cell differentiation#GO:0030154;muscle structure development#GO:0061061;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;syncytium formation by cell-cell fusion#GO:0000768;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;striated muscle cell differentiation#GO:0051146 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000011574.3|UniProtKB=A0A5F8GW40 A0A5F8GW40 PTHR15679:SF8 PCNA-ASSOCIATED FACTOR PCNA-ASSOCIATED FACTOR macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA synthesis involved in DNA replication#GO:0090592 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000048955.1|UniProtKB=A0A5F8H930 A0A5F8H930 monDomV1R1240 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000035824.2|UniProtKB=A0A5F8H812 A0A5F8H812 GSG1L PTHR10671:SF35 EPITHELIAL MEMBRANE PROTEIN-RELATED GERM CELL-SPECIFIC GENE 1-LIKE PROTEIN regulation of endocytosis#GO:0030100;regulation of synaptic plasticity#GO:0048167;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of neuronal synaptic plasticity#GO:0048168;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259 synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000002565.5|UniProtKB=F7GFA4 F7GFA4 CCDC88C PTHR18947:SF31 HOOK PROTEINS PROTEIN DAPLE binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;cytoplasmic microtubule organization#GO:0031122;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226 intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000009657.4|UniProtKB=F6QS92 F6QS92 RPL4 PTHR19431:SF0 60S RIBOSOMAL PROTEIN L4 LARGE RIBOSOMAL SUBUNIT PROTEIN UL4 structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000011210.4|UniProtKB=A0A5F8G916 A0A5F8G916 MED4 PTHR13208:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;nucleus#GO:0005634 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000018089.5|UniProtKB=F7FT76 F7FT76 PRDM13 PTHR16515:SF21 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 13 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000014957.4|UniProtKB=A0A5F8HLT8 A0A5F8HLT8 STAG2 PTHR11199:SF3 STROMAL ANTIGEN COHESIN SUBUNIT SA-2 chromatin binding#GO:0003682;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle process#GO:0022402 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;protein-containing complex#GO:0032991;cohesin complex#GO:0008278;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000006861.4|UniProtKB=F6PXN5 F6PXN5 ZFYVE1 PTHR46624:SF3 AGAP002036-PA ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 1 phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;phospholipid binding#GO:0005543;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;lipid droplet organization#GO:0034389;cellular component assembly#GO:0022607;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;lipid storage#GO:0019915 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000005055.4|UniProtKB=A0A5F8GS67 A0A5F8GS67 UNC5A PTHR12582:SF4 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5A molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 MONDO|Ensembl=ENSMODG00000019524.4|UniProtKB=F6VCJ3 F6VCJ3 MAP3K1 PTHR24361:SF414 MITOGEN-ACTIVATED KINASE KINASE KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Apoptosis signaling pathway#P00006>MEKK1#P00291;T cell activation#P00053>MEKK#P01297;FGF signaling pathway#P00021>MEKK1-5#P00634;Toll receptor signaling pathway#P00054>MEKK1#P01357;Integrin signalling pathway#P00034>ERK#P00907;Angiogenesis#P00005>MEKK1#P00208;Ras Pathway#P04393>MEKK1/4#P04543;EGF receptor signaling pathway#P00018>MEKK1-5#P00553 MONDO|Ensembl=ENSMODG00000006444.3|UniProtKB=F7EGI1 F7EGI1 HHEX PTHR24324:SF5 HOMEOBOX PROTEIN HHEX HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000043637.1|UniProtKB=A0A5F8GC37 A0A5F8GC37 PTHR41694:SF8 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 11 POL PROTEIN-LIKE binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000017824.4|UniProtKB=F6ZXC1 F6ZXC1 STK40 PTHR22961:SF16 SER/THR PROTEIN KINASE-TRB SERINE_THREONINE-PROTEIN KINASE 40 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of biological process#GO:0050789 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000048062.1|UniProtKB=A0A5F8G4Z5 A0A5F8G4Z5 RFLB PTHR12004:SF13 RELAXIN PRORELAXIN H2 intercellular signal molecule#PC00207;peptide hormone#PC00179 MONDO|Ensembl=ENSMODG00000021566.1|UniProtKB=Q65CJ2 Q65CJ2 MT-ND2 PTHR46552:SF1 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity, acting on NAD(P)H#GO:0016651;electron transfer activity#GO:0009055;NADH dehydrogenase activity#GO:0003954 aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000008777.4|UniProtKB=F6RG93 F6RG93 SYT16 PTHR46129:SF4 SYNAPTOTAGMIN 14, ISOFORM D SYNAPTOTAGMIN-16 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000045203.1|UniProtKB=A0A5F8HJF4 A0A5F8HJF4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000014974.3|UniProtKB=H9H6Q6 H9H6Q6 PTHR12629:SF6 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 2-RELATED hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 nucleoside phosphate metabolic process#GO:0006753;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;alcohol metabolic process#GO:0006066 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000025479.3|UniProtKB=F6QZ90 F6QZ90 ARSF PTHR42693:SF2 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE F hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000005668.3|UniProtKB=A0A5F8GEG8 A0A5F8GEG8 GFOD2 PTHR43818:SF8 BCDNA.GH03377 GLUCOSE-FRUCTOSE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000016060.2|UniProtKB=F7GIT8 F7GIT8 COX5B PTHR10122:SF20 CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;transporter complex#GO:1990351 oxidoreductase#PC00176;oxidase#PC00175 MONDO|Ensembl=ENSMODG00000009433.4|UniProtKB=F7BKQ1 F7BKQ1 ZBTB25 PTHR24399:SF28 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 25 DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565 regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000010846.4|UniProtKB=F7ARK8 F7ARK8 SESN2 PTHR12474:SF2 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN-2 anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;organic acid binding#GO:0043177;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;cation binding#GO:0043169;catalytic activity#GO:0003824;amino acid binding#GO:0016597;oxidoreductase activity#GO:0016491 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;response to nitrogen compound#GO:1901698;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;cellular response to nitrogen compound#GO:1901699;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;positive regulation of catabolic process#GO:0009896;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;positive regulation of macroautophagy#GO:0016239;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;response to chemical#GO:0042221;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;regulation of macroautophagy#GO:0016241;negative regulation of TORC1 signaling#GO:1904262 oxidoreductase#PC00176;peroxidase#PC00180 MONDO|Ensembl=ENSMODG00000039221.1|UniProtKB=A0A5F8GHH2 A0A5F8GHH2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000040843.1|UniProtKB=A0A5F8GW28 A0A5F8GW28 PTHR48071:SF15 SRCR DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR FAMILY 12 SUBFAMILY J MEMBER 2 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000014937.3|UniProtKB=H9H6Q2 H9H6Q2 MIF PTHR11954:SF49 D-DOPACHROME DECARBOXYLASE MACROPHAGE MIGRATION INHIBITORY FACTOR signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;catalytic activity#GO:0003824;intramolecular oxidoreductase activity#GO:0016860;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;isomerase activity#GO:0016853;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 lyase#PC00144;metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 MONDO|Ensembl=ENSMODG00000037075.1|UniProtKB=A0A5F8G2T4 A0A5F8G2T4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013840.4|UniProtKB=A0A5F8H2I4 A0A5F8H2I4 PTHR11616:SF233 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER amino acid transport#GO:0006865;transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000013567.4|UniProtKB=F7BHX6 F7BHX6 PTHR22589:SF55 CARNITINE O-ACYLTRANSFERASE PALMITOYL THIOESTERASE CPT1C catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carnitine metabolic process#GO:0009437;small molecule metabolic process#GO:0044281;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629 mitochondrion#GO:0005739;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000050335.1|UniProtKB=A0A5F8GH00 A0A5F8GH00 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000017726.4|UniProtKB=F7ELG6 F7ELG6 ST8SIA1 PTHR11987:SF3 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-N-ACETYLNEURAMINIDE ALPHA-2,8-SIALYLTRANSFERASE glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;oligosaccharide metabolic process#GO:0009311;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000013940.3|UniProtKB=F6SBW6 F6SBW6 HMGA1 PTHR23341:SF1 HIGH MOBILITY GROUP PROTEINS HMG-A AND C HIGH MOBILITY GROUP PROTEIN HMG-I_HMG-Y DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 HMG box transcription factor#PC00024 MONDO|Ensembl=ENSMODG00000007182.4|UniProtKB=F6XS39 F6XS39 PANK3 PTHR12280:SF21 PANTOTHENATE KINASE PANTOTHENATE KINASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 MONDO|Ensembl=ENSMODG00000019395.4|UniProtKB=F6WC84 F6WC84 IL16 PTHR48484:SF2 PRO-INTERLEUKIN-16 PRO-INTERLEUKIN-16 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515 Interleukin signaling pathway#P00036>Interleukin#P00970 MONDO|Ensembl=ENSMODG00000003303.3|UniProtKB=A0A5F8H245 A0A5F8H245 AP2M1 PTHR10529:SF373 AP COMPLEX SUBUNIT MU AP-2 COMPLEX SUBUNIT MU protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vacuolar transport#GO:0007034;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;receptor internalization#GO:0031623;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;Golgi to vacuole transport#GO:0006896;cellular localization#GO:0051641;localization#GO:0051179;regulation of biological quality#GO:0065008;post-Golgi vesicle-mediated transport#GO:0006892;endocytosis#GO:0006897;postsynaptic neurotransmitter receptor internalization#GO:0098884;clathrin-dependent endocytosis#GO:0072583 organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;synapse#GO:0045202;coated vesicle membrane#GO:0030662;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;coated membrane#GO:0048475;endocytic vesicle#GO:0030139;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;secretory vesicle#GO:0099503;presynapse#GO:0098793;cell junction#GO:0030054;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated endocytic vesicle#GO:0045334;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin vesicle coat#GO:0030125;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982;synaptic vesicle#GO:0008021;plasma membrane protein complex#GO:0098797;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytosol#GO:0005829;vesicle membrane#GO:0012506;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136 membrane traffic protein#PC00150 CCKR signaling map#P06959>AP2M1#P07067 MONDO|Ensembl=ENSMODG00000003962.4|UniProtKB=A0A5F8H9M1 A0A5F8H9M1 DNM3 PTHR11566:SF54 DYNAMIN DYNAMIN-3 hydrolase activity#GO:0016787;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;GTPase activity#GO:0003924;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817 organelle organization#GO:0006996;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987;synaptic vesicle recycling#GO:0036465;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;establishment of vesicle localization#GO:0051650;membrane organization#GO:0061024;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;synaptic vesicle endocytosis#GO:0048488;cellular component organization#GO:0016043;establishment of organelle localization#GO:0051656;endocytosis#GO:0006897;organelle localization#GO:0051640;localization#GO:0051179;cellular localization#GO:0051641 intracellular organelle#GO:0043229;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000020543.4|UniProtKB=F7BBU1 F7BBU1 PTHR14920:SF1 OSMOTIC AVOIDANCE ABNORMAL PROTEIN 1/WD REPEAT MEMBRANE PROTEIN WD REPEAT-CONTAINING PROTEIN 19 cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;intraciliary retrograde transport#GO:0035721;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017 intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000016914.3|UniProtKB=F6VNB0 F6VNB0 PTHR14235:SF0 OSTEOCALCIN OSTEOCALCIN small molecule binding#GO:0036094;binding#GO:0005488;structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;osteoblast differentiation#GO:0001649;cellular developmental process#GO:0048869;animal organ development#GO:0048513;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;system development#GO:0048731;cellular process#GO:0009987;bone development#GO:0060348;multicellular organismal process#GO:0032501;ossification#GO:0001503;cell differentiation#GO:0030154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000042092.1|UniProtKB=A0A5F8GY68 A0A5F8GY68 PTHR24377:SF1028 IP01015P-RELATED ZINC FINGER PROTEIN 84 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000046904.1|UniProtKB=A0A5F8GE50 A0A5F8GE50 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000049629.1|UniProtKB=A0A5F8G4W7 A0A5F8G4W7 PTHR37346:SF1 PROLINE-RICH PROTEIN 19 PROLINE-RICH PROTEIN 19 MONDO|Ensembl=ENSMODG00000044064.1|UniProtKB=F6WED1 F6WED1 LOC100030172 PTHR26453:SF119 OLFACTORY RECEPTOR ODORANT RECEPTOR M34 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006926.2|UniProtKB=F6PRH1 F6PRH1 TMEM102 PTHR10656:SF48 CELL FATE DETERMINING PROTEIN MAB21-RELATED TRANSMEMBRANE PROTEIN 102 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transferase#PC00220;nucleotidyltransferase#PC00174 FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000041374.1|UniProtKB=A0A5F8H6M1 A0A5F8H6M1 ITPKC PTHR12400:SF106 INOSITOL POLYPHOSPHATE KINASE INOSITOL-TRISPHOSPHATE 3-KINASE C phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;organophosphate biosynthetic process#GO:0090407 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 kinase#PC00137 MONDO|Ensembl=ENSMODG00000040489.1|UniProtKB=A0A5F8HA68 A0A5F8HA68 UBE2V1 PTHR24068:SF323 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 response to stress#GO:0006950;cellular process#GO:0009987;protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;macromolecule metabolic process#GO:0043170;protein K63-linked ubiquitination#GO:0070534;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to stimulus#GO:0050896;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 Toll receptor signaling pathway#P00054>Uev1A#P01376 MONDO|Ensembl=ENSMODG00000014173.3|UniProtKB=F6U7C1 F6U7C1 SETD6 PTHR13271:SF34 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE N-LYSINE METHYLTRANSFERASE SETD6 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;lysine N-methyltransferase activity#GO:0016278;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 methyltransferase#PC00155;transferase#PC00220 MONDO|Ensembl=ENSMODG00000042315.1|UniProtKB=A0A5F8GFC8 A0A5F8GFC8 LOC100018839 PTHR11467:SF179 HISTONE H1 HISTONE H1.4 chromatin DNA binding#GO:0031490;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;double-stranded DNA binding#GO:0003690 chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;chromosome condensation#GO:0030261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA recombination#GO:0000018;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of DNA recombination#GO:0045910;negative regulation of biological process#GO:0048519 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000003734.4|UniProtKB=F7EDC3 F7EDC3 WDR17 PTHR44464:SF1 WD REPEAT-CONTAINING PROTEIN 17 WD REPEAT-CONTAINING PROTEIN 17 MONDO|Ensembl=ENSMODG00000022863.2|UniProtKB=F6PHI2 F6PHI2 GPR174 PTHR24232:SF86 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 174-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015806.4|UniProtKB=F7FRY3 F7FRY3 ST7 PTHR12745:SF8 SUPPRESSION OF TUMORIGENICITY 7 SUPPRESSOR OF TUMORIGENICITY 7 PROTEIN MONDO|Ensembl=ENSMODG00000004884.3|UniProtKB=F7C2N4 F7C2N4 CC2D2B PTHR20837:SF2 CENTROSOMAL PROTEIN-RELATED PROTEIN CC2D2B cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;protein localization to cilium#GO:0061512;cellular component organization#GO:0016043;cilium assembly#GO:0060271;non-motile cilium assembly#GO:1905515;localization#GO:0051179;cilium organization#GO:0044782;organelle assembly#GO:0070925 ciliary transition zone#GO:0035869;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995 MONDO|Ensembl=ENSMODG00000040931.1|UniProtKB=A0A5F8GC31 A0A5F8GC31 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000044766.1|UniProtKB=A0A5F8HJZ6 A0A5F8HJZ6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000006252.4|UniProtKB=F6TSC9 F6TSC9 SPTAN1 PTHR11915:SF427 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell junction#GO:0030054;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;membrane#GO:0016020;cell periphery#GO:0071944 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000007009.4|UniProtKB=F6XTX6 F6XTX6 POLR2A PTHR19376:SF37 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;termination of RNA polymerase II transcription#GO:0006369;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription termination#GO:0006353;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;nucleoplasm#GO:0005654;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000017803.4|UniProtKB=F7CFH2 F7CFH2 GOPC PTHR16528:SF2 GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING PROTEIN transmembrane transporter binding#GO:0044325;binding#GO:0005488;protein binding#GO:0005515 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of protein localization#GO:0032880 transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;trans-Golgi network transport vesicle#GO:0030140;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000000790.4|UniProtKB=F6SS62 F6SS62 IFT27 PTHR47979:SF7 DRAB11-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 27 HOMOLOG hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817 microtubule-based transport#GO:0099111;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intraciliary transport particle B#GO:0030992;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000018984.4|UniProtKB=F7FP77 F7FP77 FUT10 PTHR11929:SF194 ALPHA- 1,3 -FUCOSYLTRANSFERASE GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 3 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000008049.4|UniProtKB=F6Z9Z3 F6Z9Z3 AMDHD1 PTHR42752:SF1 IMIDAZOLONEPROPIONASE IMIDAZOLONEPROPIONASE-RELATED hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000028158.2|UniProtKB=K7E520 K7E520 PTHR16675:SF289 MHC CLASS I-RELATED ZINC-ALPHA-2-GLYCOPROTEIN positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000013450.3|UniProtKB=F7G9C7 F7G9C7 TTC36 PTHR21405:SF0 CDNA SEQUENCE BC021608 TETRATRICOPEPTIDE REPEAT PROTEIN 36 MONDO|Ensembl=ENSMODG00000008656.2|UniProtKB=F6PGA1 F6PGA1 PNOC PTHR11438:SF2 PROENKEPHALIN PREPRONOCICEPTIN molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 system process#GO:0003008;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;synaptic signaling#GO:0099536;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;neuropeptide signaling pathway#GO:0007218;sensory perception of pain#GO:0019233 membrane#GO:0016020;cell periphery#GO:0071944;cell body#GO:0044297;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054 neuropeptide#PC00162;peptide hormone#PC00179;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000003718.4|UniProtKB=F7DK47 F7DK47 PTHR43943:SF15 DEHYDROGENASE/REDUCTASE (SDR FAMILY) MEMBER 4 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 4 alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000015121.2|UniProtKB=F7DJM2 F7DJM2 RUNDC1 PTHR47194:SF5 SORTING NEXIN-29-RELATED RUN DOMAIN-CONTAINING PROTEIN 1 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000024592.2|UniProtKB=A0A5F8HCT7 A0A5F8HCT7 TUBB2A PTHR36527:SF5 OS01G0282866 PROTEIN TUBULIN_FTSZ GTPASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000007511.4|UniProtKB=F7GJY3 F7GJY3 DORIP1 PTHR35350:SF1 HYPOTHETICAL LOC314168 DOPAMINE RECEPTOR-INTERACTING PROTEIN 1 MONDO|Ensembl=ENSMODG00000006337.4|UniProtKB=F7AG71 F7AG71 CEP350 PTHR13958:SF3 CENTROSOME-ASSOCIATED PROTEIN 350 CAP-GLY DOMAIN-CONTAINING PROTEIN-RELATED non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000039936.1|UniProtKB=A0A5F8GSJ7 A0A5F8GSJ7 MRPS17 PTHR24088:SF0 28S RIBOSOMAL PROTEIN S17, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN US17M cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000014540.4|UniProtKB=F7E9E2 F7E9E2 NOTCH3 PTHR24049:SF41 CRUMBS FAMILY MEMBER ATTRACTIN cell adhesion#GO:0007155;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell-cell adhesion#GO:0098609 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000020667.4|UniProtKB=F7E5K9 F7E5K9 CHIC2 PTHR13005:SF3 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN CYSTEINE-RICH HYDROPHOBIC DOMAIN-CONTAINING PROTEIN 2 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi-associated vesicle#GO:0005798;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708 MONDO|Ensembl=ENSMODG00000037978.1|UniProtKB=A0A5F8G3F7 A0A5F8G3F7 OTX1 PTHR45793:SF9 HOMEOBOX PROTEIN HOMEOBOX PROTEIN OTX1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;head development#GO:0060322;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>OTX#P06818 MONDO|Ensembl=ENSMODG00000019092.4|UniProtKB=F7FN05 F7FN05 DCK PTHR10513:SF19 DEOXYNUCLEOSIDE KINASE DEOXYCYTIDINE KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;deoxynucleoside kinase activity#GO:0019136 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000040176.1|UniProtKB=A0A5F8GA07 A0A5F8GA07 C2H6orf132 PTHR35077:SF2 SIMILAR TO AI661453 PROTEIN SIMILAR TO HUMAN CHROMOSOME 6 OPEN READING FRAME 132 MONDO|Ensembl=ENSMODG00000022833.3|UniProtKB=A0A5F8GTP2 A0A5F8GTP2 PTHR24376:SF258 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 814 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017584.4|UniProtKB=F7B5B3 F7B5B3 ARG1 PTHR43782:SF2 ARGINASE ARGINASE-1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914 small molecule metabolic process#GO:0044281;regulation of lymphocyte activation#GO:0051249;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;carboxylic acid metabolic process#GO:0019752;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;oxoacid metabolic process#GO:0043436;negative regulation of cell-cell adhesion#GO:0022408;regulation of T cell activation#GO:0050863;negative regulation of lymphocyte activation#GO:0051250;negative regulation of leukocyte activation#GO:0002695;arginine metabolic process#GO:0006525;regulation of multicellular organismal process#GO:0051239;regulation of mononuclear cell proliferation#GO:0032944;cellular process#GO:0009987;regulation of leukocyte proliferation#GO:0070663;negative regulation of T cell proliferation#GO:0042130;metabolic process#GO:0008152;regulation of T cell proliferation#GO:0042129;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;negative regulation of leukocyte cell-cell adhesion#GO:1903038;negative regulation of multicellular organismal process#GO:0051241;primary metabolic process#GO:0044238;regulation of cell population proliferation#GO:0042127;negative regulation of T cell activation#GO:0050868;negative regulation of cell adhesion#GO:0007162;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;biosynthetic process#GO:0009058;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;amino acid metabolic process#GO:0006520;negative regulation of cell population proliferation#GO:0008285;negative regulation of cell activation#GO:0050866;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000004985.4|UniProtKB=F7FKP9 F7FKP9 PTHR47083:SF1 TESTIS-EXPRESSED PROTEIN 11 TESTIS-EXPRESSED PROTEIN 11 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;homologous chromosome pairing at meiosis#GO:0007129;male meiotic nuclear division#GO:0007140;cellular component assembly#GO:0022607;synaptonemal complex assembly#GO:0007130;chromosome segregation#GO:0007059;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;cell cycle process#GO:0022402;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;gamete generation#GO:0007276;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;male gamete generation#GO:0048232;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;reciprocal homologous recombination#GO:0140527;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;homologous recombination#GO:0035825;reproductive process#GO:0022414;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;multicellular organismal reproductive process#GO:0048609;organelle fission#GO:0048285 condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;synaptonemal structure#GO:0099086;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;central element#GO:0000801;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000042661.1|UniProtKB=F7GHL9 F7GHL9 LOC100021467 PTHR11691:SF37 TYPE I INTERFERON INTERFERON OMEGA-1 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488 response to peptide#GO:1901652;cell activation involved in immune response#GO:0002263;type I interferon-mediated signaling pathway#GO:0060337;B cell activation involved in immune response#GO:0002312;immune system process#GO:0002376;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;B cell activation#GO:0042113;cell surface receptor signaling pathway#GO:0007166;leukocyte activation involved in immune response#GO:0002366;immune effector process#GO:0002252;natural killer cell activation#GO:0030101;humoral immune response#GO:0006959;T cell activation involved in immune response#GO:0002286;defense response to other organism#GO:0098542;lymphocyte activation#GO:0046649;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;defense response to symbiont#GO:0140546;lymphocyte activation involved in immune response#GO:0002285;signal transduction#GO:0007165;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cell activation#GO:0001775;cytokine-mediated signaling pathway#GO:0019221;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;response to other organism#GO:0051707;adaptive immune response#GO:0002250;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response#GO:0006955 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interferon superfamily#PC00127;cytokine#PC00083 MONDO|Ensembl=ENSMODG00000007296.4|UniProtKB=A0A5F8H119 A0A5F8H119 SLC8A3 PTHR11878:SF7 SODIUM/CALCIUM EXCHANGER SODIUM_CALCIUM EXCHANGER 3 metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;export from cell#GO:0140352;homeostatic process#GO:0042592;sodium ion transport#GO:0006814;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;sarcolemma#GO:0042383;axon#GO:0030424 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000039652.1|UniProtKB=F6RNV9 F6RNV9 LOC100021101 PTHR48018:SF32 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5L1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000041238.1|UniProtKB=A0A5F8GPF3 A0A5F8GPF3 LOC100023660 PTHR24083:SF174 NUCLEAR HORMONE RECEPTOR HEPATIC NUCLEAR FACTOR 4BETA transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000016344.4|UniProtKB=A0A5F8GXY0 A0A5F8GXY0 LOC100024299 PTHR24376:SF85 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 600-RELATED regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000019655.4|UniProtKB=A0A5F8G755 A0A5F8G755 POFUT2 PTHR13398:SF0 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000005236.3|UniProtKB=F6ZCG6 F6ZCG6 JAGN1 PTHR20955:SF4 PROTEIN JAGUNAL HOMOLOG 1 PROTEIN JAGUNAL HOMOLOG 1 response to cytokine#GO:0034097;response to chemical#GO:0042221;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;endoplasmic reticulum organization#GO:0007029;localization#GO:0051179;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000003305.4|UniProtKB=F7DZ33 F7DZ33 ST8SIA5 PTHR11987:SF4 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-2,8-SIALYLTRANSFERASE 8E glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373;catalytic activity#GO:0003824;transferase activity#GO:0016740 carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;oligosaccharide metabolic process#GO:0009311;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000015431.4|UniProtKB=F6YUN3 F6YUN3 CTDSP1 PTHR12210:SF139 DULLARD PROTEIN PHOSPHATASE CARBOXY-TERMINAL DOMAIN RNA POLYMERASE II POLYPEPTIDE A SMALL PHOSPHATASE 1 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000029253.2|UniProtKB=K7E259 K7E259 LUZP2 PTHR22414:SF0 LEUCINE ZIPPER PROTEIN 2 LEUCINE ZIPPER PROTEIN 2 MONDO|Ensembl=ENSMODG00000016258.4|UniProtKB=A0A5F8GJZ9 A0A5F8GJZ9 PREX1 PTHR22829:SF6 DEP DOMAIN PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE-DEPENDENT RAC EXCHANGER 1 PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function inhibitor activity#GO:0140678;enzyme activator activity#GO:0008047;enzyme inhibitor activity#GO:0004857;kinase inhibitor activity#GO:0019210;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;protein kinase regulator activity#GO:0019887;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GEF#P00875 MONDO|Ensembl=ENSMODG00000041026.1|UniProtKB=A0A5F8GVS5 A0A5F8GVS5 PTHR10036:SF28 CD59 GLYCOPROTEIN MAC-INHIBITORY PROTEIN MONDO|Ensembl=ENSMODG00000004162.5|UniProtKB=A0A5F8GE66 A0A5F8GE66 NSD2 PTHR22884:SF293 SET DOMAIN PROTEINS HISTONE-LYSINE N-METHYLTRANSFERASE NSD2 protein methyltransferase activity#GO:0008276;histone H3K36 methyltransferase activity#GO:0046975;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000015926.4|UniProtKB=A0A5F8HD97 A0A5F8HD97 ATAT1 PTHR12327:SF0 ALPHA-TUBULIN N-ACETYLTRANSFERASE 1 ALPHA-TUBULIN N-ACETYLTRANSFERASE 1 protein N-acyltransferase activity#GO:0140186;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;N-acetyltransferase activity#GO:0008080;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 MONDO|Ensembl=ENSMODG00000049771.1|UniProtKB=K7E1G5 K7E1G5 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000012515.4|UniProtKB=A0A5F8GBB5 A0A5F8GBB5 LOC100019334 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015330.4|UniProtKB=F6XFJ4 F6XFJ4 CPVL PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000014033.4|UniProtKB=F6URE0 F6URE0 PAFAH2 PTHR10272:SF6 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE 2, CYTOPLASMIC carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000014282.4|UniProtKB=K7E0E6 K7E0E6 DGCR6L PTHR13054:SF2 DIGEORGE SYNDROME CRITICAL REGION 6 DGCR6 FAMILY MEMBER PROTEIN DGCR6 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000016568.3|UniProtKB=F7D3R0 F7D3R0 PRSS33 PTHR24256:SF219 TRYPTASE-RELATED SERINE PROTEASE 33 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000006558.3|UniProtKB=F7BUW1 F7BUW1 PAG1 PTHR16322:SF0 PHOSPHOPROTEIN ASSOCIATED WITH GLYCOSPHINGOLIPID-ENRICHED MICRODOMAINS 1 PHOSPHOPROTEIN ASSOCIATED WITH GLYCOSPHINGOLIPID-ENRICHED MICRODOMAINS 1 negative regulation of T cell activation#GO:0050868;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of leukocyte activation#GO:0002694;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;signaling#GO:0023052;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;negative regulation of cell activation#GO:0050866;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of cell-cell adhesion#GO:0022408;negative regulation of cell adhesion#GO:0007162;regulation of T cell activation#GO:0050863;regulation of cell adhesion#GO:0030155;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695 membrane#GO:0016020;membrane raft#GO:0045121;cell periphery#GO:0071944;membrane microdomain#GO:0098857;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000015192.4|UniProtKB=A0A5F8GPD8 A0A5F8GPD8 PTPRD PTHR19134:SF430 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE DELTA catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609;synaptic membrane adhesion#GO:0099560;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;synapse organization#GO:0050808;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000007913.4|UniProtKB=F6QIH4 F6QIH4 LOC100021878 PTHR45935:SF15 PROTEIN ZBED8-RELATED SCAN DOMAIN-CONTAINING PROTEIN 3 MONDO|Ensembl=ENSMODG00000014017.4|UniProtKB=F6VAA7 F6VAA7 MTFR1L PTHR14215:SF3 PROTEIN OF UNKNOWN FUNCTION DUF729 MITOCHONDRIAL FISSION REGULATOR 1-LIKE cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;mitochondrial fission#GO:0000266;mitochondrion organization#GO:0007005;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;organelle fission#GO:0048285;cellular respiration#GO:0045333;cellular component organization or biogenesis#GO:0071840;aerobic respiration#GO:0009060 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000017825.3|UniProtKB=A0A5F8GBG5 A0A5F8GBG5 LCMT2 PTHR46529:SF1 TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4 TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4 methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;tRNA methyltransferase activity#GO:0008175 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 RNA processing factor#PC00147;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000005288.3|UniProtKB=F7E6S6 F7E6S6 FLRT3 PTHR45712:SF12 AGAP008170-PA LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT3 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000008102.3|UniProtKB=F7G5V5 F7G5V5 VAT1L PTHR44054:SF2 SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE NADPH-DEPENDENT QUINONE OXIDOREDUCTASE VAT1L-RELATED Huntington disease#P00029>PIG3#G01535 MONDO|Ensembl=ENSMODG00000004558.4|UniProtKB=F6R5C5 F6R5C5 RNF212B PTHR22663:SF29 RING FINGER PROTEIN NARYA-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF212B catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787 chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular process#GO:0009987;organelle organization#GO:0006996;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;reproductive process#GO:0022414;cell cycle process#GO:0022402;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;meiosis I#GO:0007127 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;synaptonemal structure#GO:0099086;condensed chromosome#GO:0000793;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000017190.4|UniProtKB=A0A5F8H1H6 A0A5F8H1H6 TDRD10 PTHR22948:SF12 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 10 protein binding#GO:0005515;protein kinase A binding#GO:0051018;binding#GO:0005488;protein kinase A regulatory subunit binding#GO:0034237 membrane#GO:0016020;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000039598.1|UniProtKB=K7E4B5 K7E4B5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000042297.1|UniProtKB=F7C4G3 F7C4G3 PTHR13308:SF5 NEDD4-BINDING PROTEIN 2-LIKE 1 NEDD4-BINDING PROTEIN 2-LIKE 1 MONDO|Ensembl=ENSMODG00000007110.4|UniProtKB=F6SI04 F6SI04 HID1 PTHR21575:SF12 PROTEIN HID1 PROTEIN HID1 anatomical structure development#GO:0048856;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;developmental process#GO:0032502;developmental maturation#GO:0021700;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;anatomical structure maturation#GO:0071695;Golgi organization#GO:0007030 cytosol#GO:0005829;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;Golgi stack#GO:0005795;organelle#GO:0043226;Golgi cisterna#GO:0031985;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000025707.3|UniProtKB=F6TIE4 F6TIE4 PTHR23239:SF371 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 24-LIKE structural molecule activity#GO:0005198 cytoskeleton organization#GO:0007010;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;cellular process#GO:0009987;organelle organization#GO:0006996;morphogenesis of an epithelium#GO:0002009;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000014043.4|UniProtKB=F6UQE2 F6UQE2 SETD2 PTHR46711:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096;histone H3K36 methyltransferase activity#GO:0046975;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000013013.4|UniProtKB=F7C7J2 F7C7J2 DBH PTHR10157:SF29 DOPAMINE BETA HYDROXYLASE RELATED DOPAMINE BETA-HYDROXYLASE catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 phenol-containing compound metabolic process#GO:0018958;cellular process#GO:0009987;phenol-containing compound biosynthetic process#GO:0046189;amine metabolic process#GO:0009308;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to alcohol#GO:0097305;catabolic process#GO:0009056;multicellular organismal process#GO:0032501;response to oxygen-containing compound#GO:1901700;amine catabolic process#GO:0009310;metabolic process#GO:0008152;catecholamine metabolic process#GO:0006584 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 hydroxylase#PC00122 Dopamine receptor mediated signaling pathway#P05912>DBH#P05955;Adrenaline and noradrenaline biosynthesis#P00001>DBH#P00063 MONDO|Ensembl=ENSMODG00000009959.3|UniProtKB=F6Y8J9 F6Y8J9 TRARG1 PTHR14948:SF1 NG5 TRAFFICKING REGULATOR OF GLUT4 1 intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;cellular response to insulin stimulus#GO:0032869;transport#GO:0006810;intracellular transport#GO:0046907;response to peptide hormone#GO:0043434;cellular response to nitrogen compound#GO:1901699;endosome to plasma membrane protein transport#GO:0099638;macromolecule localization#GO:0033036;response to nitrogen compound#GO:1901698;localization#GO:0051179;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;cellular response to peptide hormone stimulus#GO:0071375;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;protein localization to plasma membrane#GO:0072659;endosomal transport#GO:0016197;intracellular protein transport#GO:0006886;protein localization to cell periphery#GO:1990778;response to chemical#GO:0042221;vesicle-mediated transport#GO:0016192;cellular response to oxygen-containing compound#GO:1901701;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;response to hormone#GO:0009725;protein transport#GO:0015031;cellular localization#GO:0051641;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;endocytic recycling#GO:0032456;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;protein localization to membrane#GO:0072657;response to endogenous stimulus#GO:0009719 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;organelle#GO:0043226;cytoplasmic vesicle membrane#GO:0030659;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000687.4|UniProtKB=A0A5F8GHX5 A0A5F8GHX5 ADK PTHR45769:SF3 ADENOSINE KINASE ADENOSINE KINASE transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;nucleoside kinase activity#GO:0019206 purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000004165.2|UniProtKB=F6R9U8 F6R9U8 SNAI3 PTHR24388:SF40 ZINC FINGER PROTEIN ZINC FINGER PROTEIN SNAI3 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000023520.2|UniProtKB=F6Z2F7 F6Z2F7 PTHR12929:SF4 SOLUTE CARRIER FAMILY 52 SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 vitamin transport#GO:0051180;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;nitrogen compound transport#GO:0071705 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000029468.2|UniProtKB=K7E407 K7E407 LOC100018359 PTHR24256:SF219 TRYPTASE-RELATED SERINE PROTEASE 33 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000038176.1|UniProtKB=K7E1S8 K7E1S8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000012365.4|UniProtKB=F7DHN0 F7DHN0 PTHR16207:SF1 SET DOMAIN-CONTAINING PROTEIN PROTEIN TASOR chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;intracellular protein localization#GO:0008104;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;macromolecule localization#GO:0033036;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of macromolecule metabolic process#GO:0060255 organelle lumen#GO:0043233;chromosome#GO:0005694;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;heterochromatin#GO:0000792 MONDO|Ensembl=ENSMODG00000009913.4|UniProtKB=F6Y7Z8 F6Y7Z8 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000017272.3|UniProtKB=F6T3M3 F6T3M3 FUT7 PTHR11929:SF12 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE 7 glycosyltransferase activity#GO:0016757;alpha-(1->3)-fucosyltransferase activity#GO:0046920;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000008147.4|UniProtKB=F7ELI9 F7ELI9 CFAP210 PTHR28663:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 173 CILIA- AND FLAGELLA- ASSOCIATED PROTEIN 210 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;axoneme#GO:0005930;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasmic microtubule#GO:0005881 MONDO|Ensembl=ENSMODG00000002478.3|UniProtKB=F7BVY0 F7BVY0 PTHR13420:SF7 UPF0235 PROTEIN C15ORF40 UPF0235 PROTEIN C15ORF40 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000020550.4|UniProtKB=F7AQ46 F7AQ46 KLB PTHR10353:SF68 GLYCOSYL HYDROLASE BETA-KLOTHO hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;beta-glucosidase activity#GO:0008422;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000024656.2|UniProtKB=A0A5F8HB26 A0A5F8HB26 GREM2 PTHR15283:SF2 GREMLIN 1 GREMLIN-2 binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine binding#GO:0019955 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000013516.4|UniProtKB=F7D761 F7D761 PTHR12015:SF92 SMALL INDUCIBLE CYTOKINE A FRACTALKINE protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to external biotic stimulus#GO:0043207;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;cytokine-mediated signaling pathway#GO:0019221;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cell communication#GO:0007154;regulation of cell motility#GO:2000145;chemokine-mediated signaling pathway#GO:0070098;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;cell migration#GO:0016477;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to peptide#GO:1901652;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular process#GO:0009987;taxis#GO:0042330;response to chemical#GO:0042221;response to cytokine#GO:0034097;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000028779.2|UniProtKB=K7E2R0 K7E2R0 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000045265.1|UniProtKB=A0A5F8HDK1 A0A5F8HDK1 MIOX PTHR12588:SF0 MYOINOSITOL OXYGENASE INOSITOL OXYGENASE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;cellular process#GO:0009987 oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000002404.4|UniProtKB=F7GK52 F7GK52 PLXNA2 PTHR22625:SF37 PLEXIN PLEXIN-A2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;positive regulation of cell differentiation#GO:0045597;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of axonogenesis#GO:0050770;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;cellular component assembly#GO:0022607;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;animal gross anatomical part developmental process#GO:0160108;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;positive regulation of axonogenesis#GO:0050772;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;negative regulation of biological process#GO:0048519;regulation of cell shape#GO:0008360;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;synapse assembly#GO:0007416;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of cell differentiation#GO:0045595;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025532.3|UniProtKB=F6V1J3 F6V1J3 PTHR10010:SF23 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;phosphate transmembrane transporter activity#GO:0005315;symporter activity#GO:0015293 homeostatic process#GO:0042592;phosphate ion transport#GO:0006817;transport#GO:0006810;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;inorganic anion transport#GO:0015698;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;localization#GO:0051179;establishment of localization#GO:0051234 membrane#GO:0016020;apical plasma membrane#GO:0016324;brush border#GO:0005903;cell periphery#GO:0071944;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;organelle#GO:0043226;plasma membrane#GO:0005886;apical part of cell#GO:0045177;cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000020941.3|UniProtKB=H9H7U0 H9H7U0 PTHR19303:SF61 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 1-LIKE binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000038767.1|UniProtKB=A0A5F8GZN3 A0A5F8GZN3 SOWAHD PTHR14491:SF8 SOSONDOWAH, ISOFORM G ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHD MONDO|Ensembl=ENSMODG00000041639.1|UniProtKB=K7E3Q9 K7E3Q9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000006634.4|UniProtKB=F7G4H7 F7G4H7 PTHR23281:SF20 MERLIN/MOESIN/EZRIN/RADIXIN MERLIN cell adhesion molecule binding#GO:0050839;cytoskeletal protein binding#GO:0008092;integrin binding#GO:0005178;signaling receptor binding#GO:0005102;binding#GO:0005488;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular component biogenesis#GO:0044087;regulation of hippo signaling#GO:0035330;regulation of cellular component organization#GO:0051128;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of organelle assembly#GO:1902115;regulation of cell development#GO:0060284;negative regulation of cell population proliferation#GO:0008285;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of neurogenesis#GO:0050767;regulation of cell population proliferation#GO:0042127;regulation of nervous system development#GO:0051960 intracellular organelle#GO:0043229;filopodium#GO:0030175;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;adherens junction#GO:0005912;membraneless organelle#GO:0043228;cell junction#GO:0030054;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000046892.1|UniProtKB=A0A5F8GYJ0 A0A5F8GYJ0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003937.3|UniProtKB=F7GIR2 F7GIR2 ABCB8 PTHR24221:SF662 ATP-BINDING CASSETTE SUB-FAMILY B MITOCHONDRIAL POTASSIUM CHANNEL ATP-BINDING SUBUNIT primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000009550.4|UniProtKB=F7BJZ3 F7BJZ3 HOXD13 PTHR45804:SF4 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-D13 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000010884.5|UniProtKB=F7FVW4 F7FVW4 PHACTR4 PTHR12751:SF4 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 4 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;cell migration#GO:0016477;tissue development#GO:0009888;neural crest cell development#GO:0014032;cellular process#GO:0009987;neural crest cell migration#GO:0001755;organelle organization#GO:0006996;stem cell differentiation#GO:0048863;mesenchyme development#GO:0060485;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;animal organ development#GO:0048513;neural crest cell differentiation#GO:0014033;developmental process#GO:0032502;mesenchymal cell differentiation#GO:0048762;cell development#GO:0048468;cell differentiation#GO:0030154;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;stem cell development#GO:0048864;animal gross anatomical part developmental process#GO:0160108 phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000016196.4|UniProtKB=F7FY89 F7FY89 TOMM34 PTHR45984:SF2 RNA (RNA) POLYMERASE II ASSOCIATED PROTEIN HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM34 heat shock protein binding#GO:0031072;binding#GO:0005488;protein binding#GO:0005515 protein localization to mitochondrion#GO:0070585;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000050531.1|UniProtKB=F7E1L0 F7E1L0 monDomV1R1224 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000029706.2|UniProtKB=A0A5F8GL34 A0A5F8GL34 TMEM42 PTHR31965:SF1 TRANSMEMBRANE PROTEIN 42 TRANSMEMBRANE PROTEIN 42 MONDO|Ensembl=ENSMODG00000013146.4|UniProtKB=F7ACJ5 F7ACJ5 WARS1 PTHR10055:SF1 TRYPTOPHANYL-TRNA SYNTHETASE TRYPTOPHAN--TRNA LIGASE, CYTOPLASMIC ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000017653.5|UniProtKB=F6YKE1 F6YKE1 PTHR10985:SF79 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY_ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF-LIKE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of multicellular organismal process#GO:0051239;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cell surface receptor signaling pathway#GO:0007166;anterior/posterior pattern specification#GO:0009952;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 MONDO|Ensembl=ENSMODG00000003953.4|UniProtKB=A0A5F8HI30 A0A5F8HI30 LOC100012618 PTHR16716:SF0 CYTOCHROME C OXIDASE SUBUNIT 7B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 7B, MITOCHONDRIAL cytoplasm#GO:0005737;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;transporter complex#GO:1990351;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;oxidase#PC00175;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000006934.2|UniProtKB=F6PQX0 F6PQX0 FGF11 PTHR11486:SF67 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 11 channel regulator activity#GO:0016247;molecular function activator activity#GO:0140677;protein binding#GO:0005515;transporter regulator activity#GO:0141108;binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;fibroblast growth factor receptor binding#GO:0005104;growth factor activity#GO:0008083;ion channel regulator activity#GO:0099106;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545 positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;system development#GO:0048731;positive regulation of cellular process#GO:0048522;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000007569.3|UniProtKB=F7FPJ1 F7FPJ1 PAAF1 PTHR19857:SF19 MITOCHONDRIAL DIVISION PROTEIN 1-RELATED 26S PROTEASOME REGULATORY SUBUNIT RPN14 cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000019008.3|UniProtKB=A0A5F8G495 A0A5F8G495 PTHR11157:SF125 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 6 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000013895.4|UniProtKB=A0A5F8GLN6 A0A5F8GLN6 BLTP3A PTHR22774:SF15 CHOREIN N-TERMINAL DOMAIN-CONTAINING PROTEIN BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 3A lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;lipid transfer activity#GO:0120013 localization#GO:0051179;cellular localization#GO:0051641;lipid localization#GO:0010876;cytosolic transport#GO:0016482;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;lipid transport#GO:0006869;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 MONDO|Ensembl=ENSMODG00000041691.1|UniProtKB=A0A5F8GW09 A0A5F8GW09 LOC100027639 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000003967.5|UniProtKB=H9H640 H9H640 SPECC1L PTHR23167:SF18 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED CYTOSPIN-A actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament-based process#GO:0030029;cellular process#GO:0009987 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;actin filament#GO:0005884;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014881.4|UniProtKB=F7GGK6 F7GGK6 AGER PTHR11973:SF20 CELL SURFACE GLYCOPROTEIN MUC18-RELATED ADVANCED GLYCATION END PRODUCT-SPECIFIC RECEPTOR regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;regulation of biological quality#GO:0065008;cellular process#GO:0009987;neuron projection development#GO:0031175;response to stress#GO:0006950;microglial cell activation#GO:0001774;nervous system development#GO:0007399;myeloid leukocyte activation#GO:0002274;regulation of trans-synaptic signaling#GO:0099177;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;leukocyte activation#GO:0045321;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;inflammatory response#GO:0006954;cell activation#GO:0001775;system development#GO:0048731;anatomical structure development#GO:0048856;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of synaptic plasticity#GO:0048167;defense response#GO:0006952;neurogenesis#GO:0022008;macrophage activation#GO:0042116;cellular developmental process#GO:0048869 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000023228.1|UniProtKB=F6VEI8 F6VEI8 NHLH2 PTHR13864:SF19 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED HELIX-LOOP-HELIX PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000012440.4|UniProtKB=A0A5F8G762 A0A5F8G762 EDA2R PTHR12120:SF8 TNFR-CYS DOMAIN-CONTAINING PROTEIN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 27 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000010691.4|UniProtKB=A0A5F8H4T7 A0A5F8H4T7 NSD3 PTHR22884:SF473 SET DOMAIN PROTEINS HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;histone H3K36 methyltransferase activity#GO:0046975;catalytic activity, acting on a protein#GO:0140096;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000008397.2|UniProtKB=F7BVB0 F7BVB0 HSCB PTHR14021:SF20 IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;iron-sulfur cluster assembly#GO:0016226;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987 mitochondrion#GO:0005739;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000001467.4|UniProtKB=F7APD3 F7APD3 CHIA PTHR11177:SF188 CHITINASE ACIDIC MAMMALIAN CHITINASE chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000002778.3|UniProtKB=A0A5F8G6Z7 A0A5F8G6Z7 PTHR12606:SF11 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 2 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190 MONDO|Ensembl=ENSMODG00000008254.4|UniProtKB=F6SEM8 F6SEM8 TIAM2 PTHR46001:SF5 TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR TIAM2 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;regulation of axonogenesis#GO:0050770;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202 MONDO|Ensembl=ENSMODG00000005088.4|UniProtKB=F7A3T7 F7A3T7 IL2RG PTHR23037:SF47 CYTOKINE RECEPTOR INTERLEUKIN 2 RECEPTOR SUBUNIT GAMMA transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375 cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002249.4|UniProtKB=F7DF68 F7DF68 DNAAF6 PTHR21083:SF1 TWISTER DYNEIN AXONEMAL ASSEMBLY FACTOR 6 protein binding#GO:0005515;binding#GO:0005488 reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;sperm motility#GO:0097722;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;cilium-dependent cell motility#GO:0060285;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000002910.4|UniProtKB=A0A5F8GZ96 A0A5F8GZ96 DTL PTHR22852:SF2 LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN DENTICLELESS PROTEIN HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;mitotic G2/M transition checkpoint#GO:0044818;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;primary metabolic process#GO:0044238;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;protein metabolic process#GO:0019538;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;intracellular signal transduction#GO:0035556;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;proteasomal protein catabolic process#GO:0010498;regulation of cell cycle process#GO:0010564;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000044929.1|UniProtKB=A0A5F8H754 A0A5F8H754 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000040392.1|UniProtKB=A0A5F8HAF2 A0A5F8HAF2 NWD2 PTHR19871:SF39 BETA TRANSDUCIN-RELATED PROTEIN NACHT AND WD REPEAT DOMAIN-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000006738.4|UniProtKB=F7CDC2 F7CDC2 TNKS2 PTHR24180:SF11 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED POLY [ADP-RIBOSE] POLYMERASE TANKYRASE-2 glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of cellular component organization#GO:0051128;regulation of Wnt signaling pathway#GO:0030111;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;positive regulation of organelle organization#GO:0010638;positive regulation of metabolic process#GO:0009893;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of macromolecule metabolic process#GO:0010604;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;positive regulation of DNA metabolic process#GO:0051054;positive regulation of signal transduction#GO:0009967;localization#GO:0051179;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of telomere maintenance#GO:0032204;intracellular protein localization#GO:0008104;regulation of chromosome organization#GO:0033044;regulation of response to stimulus#GO:0048583 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase inhibitor#PC00139;kinase modulator#PC00140 MONDO|Ensembl=ENSMODG00000045482.1|UniProtKB=A0A5F8HA62 A0A5F8HA62 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000004721.4|UniProtKB=F6Y2P1 F6Y2P1 PTHR24082:SF313 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1, GROUP H, MEMBER 5 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;lipid homeostasis#GO:0055088;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of RNA biosynthetic process#GO:1902679;chemical homeostasis#GO:0048878;negative regulation of RNA metabolic process#GO:0051253;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of response to external stimulus#GO:0032102;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;homeostatic process#GO:0042592;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cholesterol homeostasis#GO:0042632;cellular developmental process#GO:0048869;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;positive regulation of DNA-templated transcription#GO:0045893 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000004785.4|UniProtKB=F7FDE6 F7FDE6 LOXL3 PTHR45817:SF2 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 3 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 oxidoreductase#PC00176;oxidase#PC00175 MONDO|Ensembl=ENSMODG00000045848.1|UniProtKB=A0A5F8HK05 A0A5F8HK05 SUB1 PTHR13215:SF0 RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000024469.1|UniProtKB=F6YI02 F6YI02 RAG2 PTHR10960:SF0 V D J RECOMBINATION-ACTIVATING PROTEIN 2 V(D)J RECOMBINATION-ACTIVATING PROTEIN 2 nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677 macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;developmental process#GO:0032502;multicellular organismal process#GO:0032501;somatic cell DNA recombination#GO:0016444;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;anatomical structure development#GO:0048856;immune system development#GO:0002520;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;V(D)J recombination#GO:0033151;somatic diversification of immune receptors#GO:0002200 protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993 MONDO|Ensembl=ENSMODG00000019410.3|UniProtKB=A0A5F8GWZ9 A0A5F8GWZ9 NAB2 PTHR12623:SF6 NGFI-A BINDING PROTEIN NGFI-A-BINDING PROTEIN 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Gonadotropin-releasing hormone receptor pathway#P06664>NAB#P06801 MONDO|Ensembl=ENSMODG00000050866.1|UniProtKB=F7EK59 F7EK59 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008911.3|UniProtKB=F7GL92 F7GL92 XKR6 PTHR16024:SF9 XK-RELATED PROTEIN XK-RELATED PROTEIN 6 phospholipid translocation#GO:0045332;membrane organization#GO:0061024;phospholipid transport#GO:0015914;biological regulation#GO:0065007;lipid transport#GO:0006869;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502;phagocytosis#GO:0006909;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cell death#GO:0008219;programmed cell death#GO:0012501;anatomical structure development#GO:0048856;localization#GO:0051179;endomembrane system organization#GO:0010256;cellular process#GO:0009987;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277;membrane invagination#GO:0010324;endocytosis#GO:0006897;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;lipid localization#GO:0010876 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000013383.2|UniProtKB=A0A5F8GDJ7 A0A5F8GDJ7 SLC25A20 PTHR45624:SF56 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL CARNITINE_ACYLCARNITINE CARRIER PROTEIN quaternary ammonium group transmembrane transporter activity#GO:0015651;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular transport#GO:0046907;transport#GO:0006810;mitochondrial transport#GO:0006839;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000018221.5|UniProtKB=F6PGM3 F6PGM3 GPR156 PTHR10519:SF80 GABA-B RECEPTOR G PROTEIN-COUPLED RECEPTOR 156-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;regulation of biological process#GO:0050789;cell communication#GO:0007154;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052 signaling receptor complex#GO:0043235;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000011918.4|UniProtKB=A0A5F8H752 A0A5F8H752 PARD6G PTHR14102:SF3 PAR-6-RELATED PARTITIONING DEFECTIVE 6 HOMOLOG GAMMA protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell-cell junction organization#GO:0045216;establishment or maintenance of cell polarity#GO:0007163;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;microtubule cytoskeleton organization#GO:0000226;cell-cell junction maintenance#GO:0045217;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;cell junction organization#GO:0034330 protein kinase complex#GO:1902911;transferase complex#GO:1990234;apical part of cell#GO:0045177;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;apical plasma membrane#GO:0016324;cell cortex#GO:0005938 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000020338.4|UniProtKB=F7FWM2 F7FWM2 PRPF19 PTHR43995:SF1 PRE-MRNA-PROCESSING FACTOR 19 PRE-MRNA-PROCESSING FACTOR 19 ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA metabolism protein#PC00031;RNA processing factor#PC00147 mRNA splicing#P00058>U4#P01476 MONDO|Ensembl=ENSMODG00000021336.3|UniProtKB=H9H7Y0 H9H7Y0 NDUFV1 PTHR11780:SF10 NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1 NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775 membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000043273.1|UniProtKB=K7E567 K7E567 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000021281.4|UniProtKB=F7GEA8 F7GEA8 IGSF10 PTHR45842:SF2 SYNAPTIC ADHESION-LIKE MOLECULE SALM IMMUNOGLOBULIN SUPERFAMILY MEMBER 10 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000016539.4|UniProtKB=F7E839 F7E839 PTHR10648:SF7 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 1 LIKE (PSEUDO structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000003689.4|UniProtKB=K7E3D9 K7E3D9 UPF1 PTHR10887:SF364 DNA2/NAM7 HELICASE FAMILY REGULATOR OF NONSENSE TRANSCRIPTS 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543 RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000015198.3|UniProtKB=F7BVQ6 F7BVQ6 CMTM6 PTHR22776:SF25 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 6 regulation of biological process#GO:0050789;immune response#GO:0006955;immune system process#GO:0002376;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896 recycling endosome#GO:0055037;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000022951.5|UniProtKB=A0A5F8G988 A0A5F8G988 SH2B1 PTHR10872:SF3 SH2B ADAPTER PROTEIN SH2B ADAPTER PROTEIN 1 signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;binding#GO:0005488;kinase binding#GO:0019900;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;signaling adaptor activity#GO:0035591;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018277.3|UniProtKB=F6Q6J4 F6Q6J4 PTHR24068:SF581 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 J1 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000014644.3|UniProtKB=F6YNW4 F6YNW4 TMEM38B PTHR12454:SF5 TRIMERIC INTRACELLULAR CATION CHANNEL TRIMERIC INTRACELLULAR CATION CHANNEL TYPE B monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;transport#GO:0006810;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;release of sequestered calcium ion into cytosol by sarcoplasmic reticulum#GO:0014808;potassium ion transport#GO:0006813 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;sarcoplasmic reticulum membrane#GO:0033017;sarcoplasmic reticulum#GO:0016529;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;sarcoplasm#GO:0016528;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000019702.3|UniProtKB=F6TC82 F6TC82 CDK7 PTHR24056:SF0 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 7 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIIH holo complex#GO:0005675;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000019194.3|UniProtKB=F7A8Y1 F7A8Y1 AREG PTHR10740:SF12 TRANSFORMING GROWTH FACTOR ALPHA AMPHIREGULIN signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 epidermal growth factor receptor signaling pathway#GO:0007173;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;positive regulation of cell cycle#GO:0045787;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic nuclear division#GO:0007088;positive regulation of mitotic nuclear division#GO:0045840;cell surface receptor signaling pathway#GO:0007166;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 MONDO|Ensembl=ENSMODG00000046887.1|UniProtKB=A0A5F8GW31 A0A5F8GW31 LOC100023092 PTHR12471:SF2 VACUOLAR ATP SYNTHASE SUBUNIT S1 V-TYPE PROTON ATPASE SUBUNIT S1 monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;biological regulation#GO:0065007;homeostatic process#GO:0042592 cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;ATPase complex#GO:1904949;proton-transporting V-type ATPase complex#GO:0033176;ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ATP synthase#PC00002;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000008192.2|UniProtKB=F7DJS8 F7DJS8 PNCK PTHR24347:SF440 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1B catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;calmodulin binding#GO:0005516;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;calcium/calmodulin-dependent protein kinase activity#GO:0004683;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000012671.6|UniProtKB=F6VH23 F6VH23 ASPM PTHR22590:SF4 MYOSIN MOTOR DOMAIN-CONTAINING PROTEIN ABNORMAL SPINDLE-LIKE MICROCEPHALY-ASSOCIATED PROTEIN MONDO|Ensembl=ENSMODG00000041868.1|UniProtKB=F7BNH3 F7BNH3 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000016807.4|UniProtKB=F7FVH6 F7FVH6 PTHR47051:SF1 NESTIN NESTIN cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;protein binding#GO:0005515 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;biological regulation#GO:0065007;regulation of protein-containing complex disassembly#GO:0043244;regulation of organelle organization#GO:0033043;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of organelle organization#GO:0010638;regulation of protein depolymerization#GO:1901879;positive regulation of cellular component organization#GO:0051130 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000000866.4|UniProtKB=F7BHN3 F7BHN3 FOXK1 PTHR45881:SF4 CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED FORKHEAD BOX PROTEIN K1 MONDO|Ensembl=ENSMODG00000014769.3|UniProtKB=F7G767 F7G767 LOC100012586 PTHR48002:SF15 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010345.4|UniProtKB=A0A5F8H4T8 A0A5F8H4T8 CUL4B PTHR11932:SF66 CULLIN CULLIN-4B binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein complex scaffold activity#GO:0140378;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;structural molecule activity#GO:0005198 protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;ribonucleoprotein complex biogenesis#GO:0022613;protein modification by small protein conjugation or removal#GO:0070647;ribosome biogenesis#GO:0042254;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ubiquitin-dependent protein catabolic process#GO:0006511 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000029695.2|UniProtKB=K7E3E5 K7E3E5 LOC103101986 PTHR35825:SF2 CASEIN KINASE II SUBUNIT ALPHA PRIME-INTERACTING PROTEIN CASEIN KINASE II SUBUNIT ALPHA'-INTERACTING PROTEIN MONDO|Ensembl=ENSMODG00000018178.3|UniProtKB=F7BU11 F7BU11 GJA10 PTHR11984:SF9 CONNEXIN GAP JUNCTION ALPHA-10 PROTEIN wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cellular process#GO:0009987;regulation of biological process#GO:0050789 anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 gap junction#PC00105;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000002974.3|UniProtKB=A0A5F8GGV9 A0A5F8GGV9 ATP6V0B PTHR10263:SF18 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 21 KDA PROTEOLIPID SUBUNIT C'' cellular anatomical structure#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000018053.4|UniProtKB=F7GEM3 F7GEM3 CD9 PTHR19282:SF163 TETRASPANIN CD9 ANTIGEN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000039042.1|UniProtKB=K7DZT5 K7DZT5 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000011742.2|UniProtKB=F7DFJ0 F7DFJ0 DPCD PTHR31921:SF1 PROTEIN DPCD PROTEIN DPCD molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of organelle assembly#GO:1902115;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;regulation of cell projection organization#GO:0031344;regulation of cilium assembly#GO:1902017;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection assembly#GO:0060491 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000043207.1|UniProtKB=A0A5F8H5J1 A0A5F8H5J1 RAB4A PTHR47979:SF73 DRAB11-RELATED RAS-RELATED PROTEIN RAB-4A nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 regulation of endocytosis#GO:0030100;transport#GO:0006810;regulation of transport#GO:0051049;regulation of localization#GO:0032879;localization#GO:0051179;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;vesicle-mediated transport#GO:0016192 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;endosome#GO:0005768;intracellular organelle#GO:0043229;recycling endosome#GO:0055037 G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000049110.1|UniProtKB=F7C1G3 F7C1G3 PTHR11909:SF20 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242;Hedgehog signaling pathway#P00025>Casein kinase I#P00681 MONDO|Ensembl=ENSMODG00000023399.3|UniProtKB=F7C9N7 F7C9N7 VN2R544 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020762.4|UniProtKB=A0A5F8GMX0 A0A5F8GMX0 PTPN13 PTHR46900:SF1 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 13 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 13 phosphoprotein phosphatase activity#GO:0004721;protein binding#GO:0005515;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphatidylinositol 3-kinase binding#GO:0043548;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of synapse assembly#GO:0051963;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;negative regulation of cellular component organization#GO:0051129;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell junction assembly#GO:1901888;regulation of signaling#GO:0023051;regulation of synapse organization#GO:0050807;regulation of intracellular signal transduction#GO:1902531;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of biological quality#GO:0065008;regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000000452.4|UniProtKB=F6USJ3 F6USJ3 RPF1 PTHR22734:SF3 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 RIBOSOME PRODUCTION FACTOR 1 binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome, large subunit precursor#GO:0030687;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000043314.1|UniProtKB=A0A5F8HG72 A0A5F8HG72 LOC103099055 PTHR11036:SF146 SEMAPHORIN HOMER SCAFFOLD PROTEIN 3 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515 nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;taxis#GO:0042330;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axon guidance#GO:0007411;axon development#GO:0061564;neurogenesis#GO:0022008;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;chemotaxis#GO:0006935 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000025675.3|UniProtKB=F6U0U5 F6U0U5 LOC103100557 PTHR45618:SF13 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL DICARBOXYLATE CARRIER C4-dicarboxylate transmembrane transporter activity#GO:0015556;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;dicarboxylic acid transmembrane transporter activity#GO:0005310;succinate transmembrane transporter activity#GO:0015141 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;succinate transport#GO:0015744;phosphate ion transport#GO:0006817;carboxylic acid transmembrane transport#GO:1905039;dicarboxylic acid transport#GO:0006835;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000017125.4|UniProtKB=F6U3F5 F6U3F5 DCST2 PTHR21041:SF6 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN DC-STAMP DOMAIN-CONTAINING PROTEIN 2 cell-cell recognition#GO:0009988;sexual reproduction#GO:0019953;cell recognition#GO:0008037;sperm-egg recognition#GO:0035036;fertilization#GO:0009566;reproductive process#GO:0022414;cellular process#GO:0009987;single fertilization#GO:0007338 MONDO|Ensembl=ENSMODG00000047783.1|UniProtKB=A0A5F8GZL5 A0A5F8GZL5 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000043274.1|UniProtKB=A0A5F8G8J9 A0A5F8G8J9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000448.4|UniProtKB=F7BMC3 F7BMC3 PPP1R16B PTHR24179:SF31 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 16B enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 anatomical structure development#GO:0048856;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of angiogenesis#GO:0045765;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;cell development#GO:0048468;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of anatomical structure morphogenesis#GO:0022603;cellular developmental process#GO:0048869;regulation of vasculature development#GO:1901342;developmental process#GO:0032502;endothelial cell differentiation#GO:0045446;regulation of response to stimulus#GO:0048583;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of multicellular organismal process#GO:0051239;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000019669.4|UniProtKB=H9H7E2 H9H7E2 TALDO1 PTHR10683:SF44 TRANSALDOLASE TRANSALDOLASE transketolase or transaldolase activity#GO:0016744;transaldolase activity#GO:0004801;catalytic activity#GO:0003824;transferase activity#GO:0016740 nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;pentose-phosphate shunt, non-oxidative branch#GO:0009052;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;glyceraldehyde-3-phosphate metabolic process#GO:0019682;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;pentose-phosphate shunt#GO:0006098;nucleotide metabolic process#GO:0009117 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 lyase#PC00144;aldolase#PC00044;metabolite interconversion enzyme#PC00262 Pentose phosphate pathway#P02762>Transaldolase#P03081 MONDO|Ensembl=ENSMODG00000013984.4|UniProtKB=F6QL09 F6QL09 PDLIM4 PTHR24214:SF6 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 4 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;system development#GO:0048731;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;heart development#GO:0007507;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 Z disc#GO:0030018;actomyosin#GO:0042641;contractile muscle fiber#GO:0043292;cell-cell junction#GO:0005911;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;actin filament#GO:0005884;I band#GO:0031674;stress fiber#GO:0001725;cytoskeleton#GO:0005856;adherens junction#GO:0005912;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;sarcomere#GO:0030017;cell junction#GO:0030054;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512;myofibril#GO:0030016;actin filament bundle#GO:0032432 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000017007.4|UniProtKB=F6QF60 F6QF60 PTHR24416:SF618 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-A RECEPTOR 5 protein kinase activity#GO:0004672;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002629.4|UniProtKB=F7FUB8 F7FUB8 SLC38A10 PTHR22950:SF646 AMINO ACID TRANSPORTER SOLUTE CARRIER FAMILY 38 MEMBER 10 carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;amino acid transporter#PC00046 MONDO|Ensembl=ENSMODG00000012273.4|UniProtKB=A0A5F8H184 A0A5F8H184 SLC38A3 PTHR22950:SF22 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 3 carboxylic acid transmembrane transporter activity#GO:0046943;aromatic amino acid transmembrane transporter activity#GO:0015173;basic amino acid transmembrane transporter activity#GO:0015174;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;L-amino acid transmembrane transporter activity#GO:0015179 neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179;amino acid transport#GO:0006865;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;amino acid transporter#PC00046 MONDO|Ensembl=ENSMODG00000016682.4|UniProtKB=F6ZW91 F6ZW91 CAPN15 PTHR10183:SF382 CALPAIN CALPAIN-15 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000040670.1|UniProtKB=A0A5F8GVI3 A0A5F8GVI3 PTHR23262:SF248 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-6 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000006184.4|UniProtKB=F6T0B9 F6T0B9 CREBRF PTHR21552:SF2 ADULT RETINA PROTEIN CREB3 REGULATORY FACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000028020.2|UniProtKB=K7E2K1 K7E2K1 PTHR43323:SF1 3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE HYDROXYMETHYLGLUTARYL-COA SYNTHASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 acetyl-CoA metabolic process#GO:0006084;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000008658.4|UniProtKB=F6PG58 F6PG58 ATG4B PTHR22624:SF39 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4B hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;protein-phosphatidylethanolamide deconjugating activity#GO:0019786;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096 autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;biosynthetic process#GO:0009058;proteolysis#GO:0006508;organelle assembly#GO:0070925;protein metabolic process#GO:0019538;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000014293.5|UniProtKB=A0A5F8GUT5 A0A5F8GUT5 MED13 PTHR48249:SF4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000029197.1|UniProtKB=K7DZL8 K7DZL8 PTHR24377:SF1052 IP01015P-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000027321.2|UniProtKB=K7E4A5 K7E4A5 PTHR24147:SF53 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN 26 MONDO|Ensembl=ENSMODG00000013436.4|UniProtKB=F6WI51 F6WI51 SNX2 PTHR10555:SF31 SORTING NEXIN SORTING NEXIN-2 ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;retromer complex#GO:0030904;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000011103.4|UniProtKB=A0A5F8GN48 A0A5F8GN48 DSC2 PTHR24025:SF0 DESMOGLEIN FAMILY MEMBER DESMOCOLLIN-2 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 cadherin#PC00057 MONDO|Ensembl=ENSMODG00000047609.1|UniProtKB=A0A5F8GIX8 A0A5F8GIX8 PTHR23226:SF184 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 29 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008899.4|UniProtKB=F7B4F2 F7B4F2 DLX2 PTHR24327:SF23 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-2 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 embryo development#GO:0009790;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;embryo development ending in birth or egg hatching#GO:0009792;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000003412.5|UniProtKB=F7GKW2 F7GKW2 ZBTB7C PTHR46105:SF7 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 7C sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000000409.4|UniProtKB=F6QME7 F6QME7 SSX2IP PTHR46507:SF1 AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN cellular component organization#GO:0016043;cilium assembly#GO:0060271;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;intraciliary transport involved in cilium assembly#GO:0035735;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;centrosome#GO:0005813;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;cell projection#GO:0042995;centriolar satellite#GO:0034451;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000006841.3|UniProtKB=F6PFY4 F6PFY4 USH1C PTHR23116:SF36 PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED HARMONIN cell development#GO:0048468;cell projection organization#GO:0030030;sensory perception of sound#GO:0007605;cell differentiation#GO:0030154;inner ear receptor cell stereocilium organization#GO:0060122;cellular component organization#GO:0016043;system development#GO:0048731;neuron development#GO:0048666;ear development#GO:0043583;anatomical structure development#GO:0048856;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;generation of neurons#GO:0048699;nervous system process#GO:0050877;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;inner ear development#GO:0048839;system process#GO:0003008;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;sensory organ development#GO:0007423 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;stereocilium#GO:0032420;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;photoreceptor inner segment#GO:0001917;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000006869.4|UniProtKB=F6PX24 F6PX24 PTHR12259:SF2 RGS-GAIP INTERACTING PROTEIN GIPC PDZ DOMAIN-CONTAINING PROTEIN GIPC3 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000375.4|UniProtKB=F6R929 F6R929 PTHR10907:SF54 REGUCALCIN REGUCALCIN hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of calcium-mediated signaling#GO:0050848;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;esterase#PC00097 MONDO|Ensembl=ENSMODG00000012298.3|UniProtKB=H9H6J9 H9H6J9 PTHR24381:SF479 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 432 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011512.3|UniProtKB=F6UIV0 F6UIV0 ARMH3 PTHR13608:SF3 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000001878.4|UniProtKB=A0A5F8G4K4 A0A5F8G4K4 TRPC4AP PTHR31743:SF1 TRANSIENT RECEPTOR POTENTIAL CHANNEL 4-ASSOCIATED PROTEIN TCPC4AP SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 4-ASSOCIATED PROTEIN protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000005036.4|UniProtKB=F7EIB0 F7EIB0 CPNE9 PTHR10857:SF112 COPINE COPINE-9 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to metal ion#GO:0010038;response to calcium ion#GO:0051592;response to chemical#GO:0042221;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000009166.4|UniProtKB=F7ADU0 F7ADU0 PGBD5 PTHR28576:SF2 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 5 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 5 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001096.4|UniProtKB=A0A5F8HH95 A0A5F8HH95 HYCC1 PTHR31220:SF4 HYCCIN RELATED HYCCIN biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule localization#GO:0033036;organophosphate metabolic process#GO:0019637;intracellular protein localization#GO:0008104;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;protein localization to cell periphery#GO:1990778;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;protein localization to membrane#GO:0072657;phosphorus metabolic process#GO:0006793;protein localization to plasma membrane#GO:0072659;primary metabolic process#GO:0044238;localization#GO:0051179;organophosphate biosynthetic process#GO:0090407;cellular localization#GO:0051641;localization within membrane#GO:0051668;phosphatidylinositol phosphate biosynthetic process#GO:0046854 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000037262.1|UniProtKB=A0A5F8GPF1 A0A5F8GPF1 VN2R585 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000044530.1|UniProtKB=A0A5F8HB31 A0A5F8HB31 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000038140.1|UniProtKB=A0A5F8GBP5 A0A5F8GBP5 ZBED1 PTHR46169:SF2 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A E3 SUMO-PROTEIN LIGASE ZBED1 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000007501.4|UniProtKB=F6YX78 F6YX78 ARHGEF39 PTHR47056:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 39 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 39 biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of cell migration#GO:0030335;positive regulation of cell motility#GO:2000147;positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145;regulation of cell migration#GO:0030334 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000045204.1|UniProtKB=K7E5G4 K7E5G4 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000000367.3|UniProtKB=F6R986 F6R986 BCAS2 PTHR13296:SF0 BCAS2 PROTEIN PRE-MRNA-SPLICING FACTOR SPF27 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000009867.4|UniProtKB=A0A5F8G6E4 A0A5F8G6E4 CAPRIN1 PTHR22922:SF3 GPI-ANCHORED PROTEIN P137 CAPRIN-1 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000024862.2|UniProtKB=F7A966 F7A966 PTHR14386:SF2 PROTEIN FAM204A PROTEIN FAM204A MONDO|Ensembl=ENSMODG00000017997.4|UniProtKB=F7B7U4 F7B7U4 RIMKLB PTHR21621:SF5 RIBOSOMAL PROTEIN S6 MODIFICATION PROTEIN BETA-CITRYLGLUTAMATE SYNTHASE B ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000038217.1|UniProtKB=F6S960 F6S960 PTHR26452:SF256 OLFACTORY RECEPTOR OLFACTORY RECEPTOR FAMILY 12 SUBFAMILY J MEMBER 2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010033.4|UniProtKB=F6TUH7 F6TUH7 PTHR11537:SF265 VOLTAGE-GATED POTASSIUM CHANNEL A-TYPE VOLTAGE-GATED POTASSIUM CHANNEL KCND2 voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 action potential#GO:0001508;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391 synaptic membrane#GO:0097060;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;dendritic tree#GO:0097447;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495;dendritic spine#GO:0043197;plasma membrane protein complex#GO:0098797;cell body#GO:0044297;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;cell projection#GO:0042995;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;synapse#GO:0045202 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000001322.4|UniProtKB=A0A5F8GNI2 A0A5F8GNI2 CLCN1 PTHR45720:SF4 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN 1 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic anion channel activity#GO:0008308;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;chloride transport#GO:0006821;monoatomic anion transport#GO:0006820 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000004306.4|UniProtKB=F6XXV4 F6XXV4 LOC100619984 PTHR24376:SF85 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 600-RELATED regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000002053.4|UniProtKB=A0A5F8HA95 A0A5F8HA95 FNIP2 PTHR21634:SF11 RE13835P FOLLICULIN-INTERACTING PROTEIN 2 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000000347.4|UniProtKB=F6RUR1 F6RUR1 PLCXD1 PTHR13593:SF24 FAMILY NOT NAMED PI-PLC X DOMAIN-CONTAINING PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 MONDO|Ensembl=ENSMODG00000017979.4|UniProtKB=F7BUT7 F7BUT7 NANOG PTHR24327:SF72 HOMEOBOX PROTEIN HOMEOBOX PROTEIN NANOG RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;stem cell population maintenance#GO:0019827;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;maintenance of cell number#GO:0098727;regulation of biological process#GO:0050789 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000017557.4|UniProtKB=A0A5F8GR42 A0A5F8GR42 G2E3 PTHR12420:SF37 PHD FINGER PROTEIN G2_M PHASE-SPECIFIC E3 UBIQUITIN-PROTEIN LIGASE ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 negative regulation of programmed cell death#GO:0043069;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000011566.4|UniProtKB=F6QBJ8 F6QBJ8 HIBCH PTHR43176:SF38 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000016842.4|UniProtKB=F6QHV0 F6QHV0 YTHDF1 PTHR12357:SF65 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN 1 RNA binding#GO:0003723;protein-RNA adaptor activity#GO:0140517;nucleic acid binding#GO:0003676;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;mRNA binding#GO:0003729 positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;organelle assembly#GO:0070925;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;positive regulation of RNA metabolic process#GO:0051254;cytoplasmic stress granule assembly#GO:0034063;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000017476.4|UniProtKB=A0A5F8H327 A0A5F8H327 AHI1 PTHR44499:SF1 JOUBERIN JOUBERIN cilium organization#GO:0044782;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815 MONDO|Ensembl=ENSMODG00000047615.1|UniProtKB=A0A5F8H2L7 A0A5F8H2L7 KLHDC7B PTHR45972:SF5 BTB_2 DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 7B MONDO|Ensembl=ENSMODG00000024732.1|UniProtKB=F7DXV9 F7DXV9 MMGT1 PTHR21181:SF7 ER membrane protein complex subunit 5-related ER MEMBRANE PROTEIN COMPLEX SUBUNIT 5 protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104 protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;EMC complex#GO:0072546 MONDO|Ensembl=ENSMODG00000008434.4|UniProtKB=A0A5F8G9F9 A0A5F8G9F9 ATE1 PTHR21367:SF1 ARGININE-TRNA-PROTEIN TRANSFERASE 1 ARGINYL-TRNA--PROTEIN TRANSFERASE 1 catalytic activity, acting on RNA#GO:0140098;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;acyltransferase activity#GO:0016746 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 translational protein#PC00263 MONDO|Ensembl=ENSMODG00000023470.1|UniProtKB=F6T6U1 F6T6U1 HTR1B PTHR24247:SF16 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1B neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cellular process#GO:0009987;signal transduction#GO:0007165;synaptic signaling#GO:0099536;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 MONDO|Ensembl=ENSMODG00000028107.2|UniProtKB=K7DZ10 K7DZ10 LOC103102448 PTHR10015:SF336 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK TRANSCRIPTION FACTOR, Y-LINKED helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000039914.1|UniProtKB=A0A5F8GXS7 A0A5F8GXS7 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000007900.4|UniProtKB=F6YSL5 F6YSL5 C1H10orf120 PTHR47509:SF1 MCG1612 SIMILAR TO HUMAN CHROMOSOME 10 OPEN READING FRAME 120 MONDO|Ensembl=ENSMODG00000044744.1|UniProtKB=A0A5F8G999 A0A5F8G999 PTHR11954:SF22 D-DOPACHROME DECARBOXYLASE D-DOPACHROME DECARBOXYLASE catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;lyase#PC00144;decarboxylase#PC00089 MONDO|Ensembl=ENSMODG00000002094.4|UniProtKB=F6UHD5 F6UHD5 FASTKD3 PTHR21228:SF9 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;regulation of RNA stability#GO:0043487;mitochondrial RNA metabolic process#GO:0000959;regulation of RNA metabolic process#GO:0051252;mitochondrial gene expression#GO:0140053;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000018578.4|UniProtKB=F7FRB4 F7FRB4 TIMM10B PTHR13172:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 B molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597 membrane-enclosed lumen#GO:0031974;mitochondrial envelope#GO:0005740;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial intermembrane space#GO:0005758;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000005406.4|UniProtKB=F7G620 F7G620 NOXRED1 PTHR11645:SF58 PYRROLINE-5-CARBOXYLATE REDUCTASE NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058 metabolite interconversion enzyme#PC00262;reductase#PC00198 MONDO|Ensembl=ENSMODG00000045030.1|UniProtKB=A0A5F8HL97 A0A5F8HL97 PTHR23238:SF3 RNA BINDING PROTEIN RNA-BINDING PROTEIN EWS transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;RNA binding#GO:0003723 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000004972.4|UniProtKB=A0A5F8GV34 A0A5F8GV34 KLKB1 PTHR24253:SF64 TRANSMEMBRANE PROTEASE SERINE PLASMA KALLIKREIN serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 negative regulation of multicellular organismal process#GO:0051241;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;regulation of coagulation#GO:0050818;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;biosynthetic process#GO:0009058;plasminogen activation#GO:0031639;negative regulation of wound healing#GO:0061045;regulation of hemostasis#GO:1900046;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;macromolecule metabolic process#GO:0043170;negative regulation of blood coagulation#GO:0030195;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of blood coagulation#GO:0030193;regulation of body fluid levels#GO:0050878;regulation of wound healing#GO:0061041;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;zymogen activation#GO:0031638;negative regulation of coagulation#GO:0050819;regulation of biological quality#GO:0065008;proteolysis#GO:0006508;negative regulation of hemostasis#GO:1900047;regulation of response to external stimulus#GO:0032101;protein maturation#GO:0051604;gene expression#GO:0010467;negative regulation of response to external stimulus#GO:0032102;regulation of multicellular organismal process#GO:0051239;regulation of response to wounding#GO:1903034;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of response to wounding#GO:1903035;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 Blood coagulation#P00011>Prekallikrein#P00439;Blood coagulation#P00011>Kallikrein#P00437 MONDO|Ensembl=ENSMODG00000002202.3|UniProtKB=F7G3Q0 F7G3Q0 PUS10 PTHR21568:SF0 TRNA PSEUDOURIDINE SYNTHASE PUS10 TRNA PSEUDOURIDINE SYNTHASE PUS10 catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;catalytic activity, acting on a tRNA#GO:0140101 cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;primary miRNA processing#GO:0031053;tRNA processing#GO:0008033;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;tRNA modification#GO:0006400;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;macromolecule modification#GO:0043412 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000017886.3|UniProtKB=F7GFM1 F7GFM1 FAM229B PTHR35355:SF2 PROTEIN FAM229A PROTEIN FAM229B MONDO|Ensembl=ENSMODG00000009313.5|UniProtKB=A0A5F8H5H6 A0A5F8H5H6 PTHR24543:SF320 MULTICOPPER OXIDASE-RELATED COAGULATION FACTOR VIII metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;blood coagulation#GO:0007596;response to stress#GO:0006950;response to wounding#GO:0009611;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;coagulation#GO:0050817;protein maturation#GO:0051604;gene expression#GO:0010467;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;biosynthetic process#GO:0009058;blood coagulation, fibrin clot formation#GO:0072378;protein metabolic process#GO:0019538;protein activation cascade#GO:0072376;wound healing#GO:0042060;regulation of biological quality#GO:0065008;hemostasis#GO:0007599;primary metabolic process#GO:0044238;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 Blood coagulation#P00011>FVIII#P00405;Blood coagulation#P00011>FVIIIa#P00446 MONDO|Ensembl=ENSMODG00000010438.4|UniProtKB=F6YT13 F6YT13 SPG21 PTHR15913:SF1 ACID CLUSTER PROTEIN 33 MASPARDIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;trans-Golgi network transport vesicle#GO:0030140;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytosol#GO:0005829;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136 MONDO|Ensembl=ENSMODG00000025655.2|UniProtKB=F6XDV0 F6XDV0 PTHR23023:SF70 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000012411.4|UniProtKB=F6PME9 F6PME9 NETO1 PTHR24251:SF27 OVOCHYMASE-RELATED NEUROPILIN AND TOLLOID-LIKE PROTEIN 1 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;protein localization to cell junction#GO:1902414;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular localization#GO:0051641;regulation of protein localization to membrane#GO:1905475;cellular process#GO:0009987;macromolecule localization#GO:0033036;biological regulation#GO:0065007;protein localization to cell periphery#GO:1990778;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular protein localization#GO:0008104;regulation of localization#GO:0032879;protein localization to synapse#GO:0035418 synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000025274.1|UniProtKB=F7A3B0 F7A3B0 LOC100028642 PTHR26452:SF125 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13A1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019534.4|UniProtKB=F6UV20 F6UV20 ANPEP PTHR11533:SF172 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE N metalloexopeptidase activity#GO:0008235;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;exopeptidase activity#GO:0008238 macromolecule metabolic process#GO:0043170;system process#GO:0003008;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;hormone metabolic process#GO:0042445;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;peptide hormone processing#GO:0016486;peptide catabolic process#GO:0043171;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of biological quality#GO:0065008;peptide metabolic process#GO:0006518;circulatory system process#GO:0003013;proteolysis#GO:0006508;catabolic process#GO:0009056;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000039182.1|UniProtKB=A0A5F8GGH6 A0A5F8GGH6 HMGB2 PTHR48112:SF3 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B2 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 MONDO|Ensembl=ENSMODG00000015252.4|UniProtKB=F6U3X4 F6U3X4 PTHR37347:SF1 MEGAKARYOCYTE AND PLATELET INHIBITORY RECEPTOR G6B MEGAKARYOCYTE AND PLATELET INHIBITORY RECEPTOR G6B regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;hemostasis#GO:0007599;negative regulation of multicellular organismal process#GO:0051241;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of platelet activation#GO:0010543;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;regulation of coagulation#GO:0050818;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of wound healing#GO:0061045;response to wounding#GO:0009611;regulation of hemostasis#GO:1900046;negative regulation of cell activation#GO:0050866;blood coagulation#GO:0007596;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;negative regulation of blood coagulation#GO:0030195;regulation of response to stimulus#GO:0048583;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;response to stimulus#GO:0050896;regulation of wound healing#GO:0061041;signaling#GO:0023052;integrin-mediated signaling pathway#GO:0007229;negative regulation of biological process#GO:0048519;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;negative regulation of coagulation#GO:0050819;wound healing#GO:0042060;negative regulation of cell communication#GO:0010648;regulation of biological quality#GO:0065008;regulation of platelet aggregation#GO:0090330;negative regulation of signaling#GO:0023057;negative regulation of hemostasis#GO:1900047;regulation of signaling#GO:0023051;regulation of response to external stimulus#GO:0032101;negative regulation of cell-cell adhesion#GO:0022408;regulation of multicellular organismal process#GO:0051239;negative regulation of signal transduction#GO:0009968;negative regulation of response to external stimulus#GO:0032102;response to stress#GO:0006950;regulation of response to wounding#GO:1903034;cellular process#GO:0009987;signal transduction#GO:0007165;coagulation#GO:0050817;negative regulation of response to wounding#GO:1903035;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040866.1|UniProtKB=A0A5F8H886 A0A5F8H886 KRTAP8-1 PTHR36131:SF1 KERATIN-ASSOCIATED PROTEIN 8-1 KERATIN-ASSOCIATED PROTEIN 8-1 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000009695.4|UniProtKB=F6Y2F6 F6Y2F6 MRC1 PTHR22803:SF104 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED MACROPHAGE MANNOSE RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000005432.4|UniProtKB=F7D0P2 F7D0P2 DPP4 PTHR11731:SF128 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE 4 peptidase activity#GO:0008233;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000036427.1|UniProtKB=A0A5F8GQP9 A0A5F8GQP9 HIF1AN PTHR12461:SF108 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 negative regulation of signal transduction#GO:0009968;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of Notch signaling pathway#GO:0045746;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;negative regulation of signaling#GO:0023057 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000006344.4|UniProtKB=F7AFL4 F7AFL4 CYP26A1 PTHR24286:SF101 CYTOCHROME P450 26 CYTOCHROME P450 26A1 catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 regulation of hormone levels#GO:0010817;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;central nervous system development#GO:0007417;catabolic process#GO:0009056;terpenoid metabolic process#GO:0006721;oxoacid metabolic process#GO:0043436;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;isoprenoid metabolic process#GO:0006720;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;hormone metabolic process#GO:0042445;multicellular organismal process#GO:0032501;monocarboxylic acid catabolic process#GO:0072329;developmental process#GO:0032502;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;diterpenoid metabolic process#GO:0016101;multicellular organism development#GO:0007275;retinoid metabolic process#GO:0001523 oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000007923.4|UniProtKB=F6R2Y0 F6R2Y0 PTHR10579:SF52 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;chloride channel activity#GO:0005254;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000051362.1|UniProtKB=A0A5F8G7Y0 A0A5F8G7Y0 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000013585.4|UniProtKB=F7AVX2 F7AVX2 KLHL40 PTHR24412:SF22 KELCH PROTEIN KELCH-LIKE PROTEIN 40 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;striated muscle cell differentiation#GO:0051146;animal organ development#GO:0048513;striated muscle tissue development#GO:0014706;muscle organ development#GO:0007517;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;proteasomal protein catabolic process#GO:0010498;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;regulation of post-translational protein modification#GO:1901873;striated muscle cell development#GO:0055002;negative regulation of protein ubiquitination#GO:0031397;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;negative regulation of metabolic process#GO:0009892;cell development#GO:0048468;cell differentiation#GO:0030154;negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of protein modification process#GO:0031399;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of protein ubiquitination#GO:0031396;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biological regulation#GO:0065007;tissue development#GO:0009888;negative regulation of macromolecule metabolic process#GO:0010605;skeletal muscle tissue development#GO:0007519;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of catabolic process#GO:0009895;muscle tissue development#GO:0060537;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of protein metabolic process#GO:0051248;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;muscle cell differentiation#GO:0042692;modification-dependent protein catabolic process#GO:0019941;muscle cell development#GO:0055001;primary metabolic process#GO:0044238 A band#GO:0031672;cullin-RING ubiquitin ligase complex#GO:0031461;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;myofibril#GO:0030016;contractile muscle fiber#GO:0043292;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;I band#GO:0031674;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;sarcomere#GO:0030017;Cul3-RING ubiquitin ligase complex#GO:0031463;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014394.3|UniProtKB=F6SRJ7 F6SRJ7 PLPPR1 PTHR10165:SF41 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;phosphate-containing compound metabolic process#GO:0006796;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;dephosphorylation#GO:0016311;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 phosphatase#PC00181;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000015244.3|UniProtKB=F6UJI5 F6UJI5 DDAH2 PTHR12737:SF16 DIMETHYLARGININE DIMETHYLAMINOHYDROLASE HYDROLASE DDAH2-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;oxoacid metabolic process#GO:0043436;regulation of cellular process#GO:0050794;small molecule metabolic process#GO:0044281;regulation of biological process#GO:0050789;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;regulation of biosynthetic process#GO:0009889;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000050476.1|UniProtKB=A0A5F8GXL1 A0A5F8GXL1 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000004770.4|UniProtKB=F6WKY0 F6WKY0 ALG8 PTHR12413:SF2 DOLICHYL GLYCOSYLTRANSFERASE DOLICHYL PYROPHOSPHATE GLC1MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000046638.1|UniProtKB=K7E3U6 K7E3U6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000047730.1|UniProtKB=A0A5F8H6U1 A0A5F8H6U1 PTHR10505:SF4 CALCITONIN-RELATED ISLET AMYLOID POLYPEPTIDE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 MONDO|Ensembl=ENSMODG00000014632.4|UniProtKB=A0A5F8H4J6 A0A5F8H4J6 TRIM37 PTHR36754:SF2 E3 UBIQUITIN-PROTEIN LIGASE TRIM37 E3 UBIQUITIN-PROTEIN LIGASE TRIM37 enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;cytokine receptor binding#GO:0005126;binding#GO:0005488;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;signaling receptor binding#GO:0005102;ubiquitin-like protein ligase binding#GO:0044389;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;ubiquitin protein ligase binding#GO:0031625;tumor necrosis factor receptor superfamily binding#GO:0032813;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;cellular component assembly#GO:0022607;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular component biogenesis#GO:0044085;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000010645.4|UniProtKB=A0A5F8GG95 A0A5F8GG95 HK1 PTHR19443:SF10 HEXOKINASE HEXOKINASE-1 catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;hexokinase activity#GO:0004396 nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;catabolic process#GO:0009056;glucose 6-phosphate metabolic process#GO:0051156;nucleoside phosphate metabolic process#GO:0006753;homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;nucleobase-containing compound catabolic process#GO:0034655;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;intracellular chemical homeostasis#GO:0055082;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;ribonucleoside diphosphate metabolic process#GO:0009185;carbohydrate homeostasis#GO:0033500;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;oxoacid metabolic process#GO:0043436;intracellular glucose homeostasis#GO:0001678;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;ADP metabolic process#GO:0046031;cellular homeostasis#GO:0019725;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;pyruvate metabolic process#GO:0006090;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ADP catabolic process#GO:0046032;purine nucleoside diphosphate catabolic process#GO:0009137;glucose homeostasis#GO:0042593;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasmic side of membrane#GO:0098562;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cytosol#GO:0005829;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;outer membrane#GO:0019867;intracellular organelle#GO:0043229;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 Glycolysis#P00024>Hexokinase#P00677;Pentose phosphate pathway#P02762>Hexokinase#P03079;Fructose galactose metabolism#P02744>Hexokinase#P02966 MONDO|Ensembl=ENSMODG00000007350.5|UniProtKB=F7ADU8 F7ADU8 SLC16A12 PTHR11360:SF318 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 12 carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monocarboxylic acid transmembrane transporter activity#GO:0008028 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178 transporter#PC00227 MONDO|Ensembl=ENSMODG00000039051.1|UniProtKB=A0A5F8GLV9 A0A5F8GLV9 PTHR10885:SF24 ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824 cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;metabolic process#GO:0008152;isoprenoid metabolic process#GO:0006720;organophosphate biosynthetic process#GO:0090407 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;peroxisome#GO:0005777;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 isomerase#PC00135 MONDO|Ensembl=ENSMODG00000002887.3|UniProtKB=A0A5F8HGT7 A0A5F8HGT7 COMMD1 PTHR21199:SF1 COMM DOMAIN-CONTAINING PROTEIN 1 COMM DOMAIN-CONTAINING PROTEIN 1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein metabolic process#GO:0051247;regulation of protein catabolic process#GO:0042176;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;localization#GO:0051179;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;positive regulation of protein ubiquitination#GO:0031398;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;regulation of protein ubiquitination#GO:0031396;transport#GO:0006810;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of catabolic process#GO:0009894;regulation of protein modification process#GO:0031399;establishment of localization#GO:0051234 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000007683.3|UniProtKB=F7FN78 F7FN78 PTHR14303:SF0 DNA POLYMERASE DELTA SUBUNIT 4 DNA POLYMERASE DELTA SUBUNIT 4 catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;DNA-directed DNA polymerase activity#GO:0003887 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA-templated DNA replication#GO:0006261;response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;replication fork#GO:0005657;replisome#GO:0030894;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear replication fork#GO:0043596;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575 DNA metabolism protein#PC00009;DNA-directed DNA polymerase#PC00018 MONDO|Ensembl=ENSMODG00000045334.1|UniProtKB=A0A5F8GGX3 A0A5F8GGX3 PTHR24388:SF109 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 221-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000040849.1|UniProtKB=K7DZ50 K7DZ50 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016014.4|UniProtKB=F7EG37 F7EG37 TSC2 PTHR10063:SF0 TUBERIN TUBERIN nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;positive regulation of macroautophagy#GO:0016239;signaling#GO:0023052;negative regulation of TORC1 signaling#GO:1904262;regulation of macroautophagy#GO:0016241;positive regulation of autophagy#GO:0010508;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;intracellular signaling cassette#GO:0141124;negative regulation of signal transduction#GO:0009968;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;positive regulation of catabolic process#GO:0009896;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GTPase-activating protein#PC00257;G-protein modulator#PC00022 p53 pathway by glucose deprivation#P04397>TSC2#P04644;p53 pathway by glucose deprivation#P04397>TSC2#G04706;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>TSC2#P04494 MONDO|Ensembl=ENSMODG00000000583.4|UniProtKB=F6WNZ4 F6WNZ4 TTC29 PTHR46630:SF2 TETRATRICOPEPTIDE REPEAT PROTEIN 29 TETRATRICOPEPTIDE REPEAT PROTEIN 29 cilium movement#GO:0003341;cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 cilium#GO:0005929;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000018394.4|UniProtKB=F6QAG5 F6QAG5 CCDC77 PTHR22091:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 77 COILED-COIL DOMAIN-CONTAINING PROTEIN 77 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000009939.4|UniProtKB=A0A5F8GSH2 A0A5F8GSH2 PTHR36864:SF1 CANCER-ASSOCIATED GENE 1 PROTEIN CANCER-ASSOCIATED GENE 1 PROTEIN MONDO|Ensembl=ENSMODG00000039145.1|UniProtKB=A0A5F8HGE3 A0A5F8HGE3 DCUN1D1 PTHR12281:SF10 RP42 RELATED DCN1-LIKE PROTEIN 1 ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;protein binding#GO:0005515;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;positive regulation of macromolecule metabolic process#GO:0010604;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;regulation of protein modification process#GO:0031399;positive regulation of protein metabolic process#GO:0051247 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000013300.4|UniProtKB=F6ZJC0 F6ZJC0 VPS11 PTHR23323:SF24 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;organelle fusion#GO:0048284;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;vesicle organization#GO:0016050;vacuole organization#GO:0007033 vesicle tethering complex#GO:0099023;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000010623.4|UniProtKB=A0A5F8HGX9 A0A5F8HGX9 ADD3 PTHR10672:SF5 ADDUCIN GAMMA-ADDUCIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 regulation of actin cytoskeleton organization#GO:0032956;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of actin filament length#GO:0030832;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;regulation of protein depolymerization#GO:1901879;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament depolymerization#GO:0030834;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex assembly#GO:0031333;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272 postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000020979.4|UniProtKB=F6S588 F6S588 ETS2 PTHR11849:SF188 ETS PROTEIN C-ETS-2 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000014098.4|UniProtKB=F6QJN6 F6QJN6 TRIM63 PTHR24103:SF570 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM63 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000015922.3|UniProtKB=F6ZR18 F6ZR18 ZNF277 PTHR13267:SF3 ZINC FINGER PROTEIN 277 ZINC FINGER PROTEIN 277 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000017783.4|UniProtKB=F7D003 F7D003 FAM184A PTHR18870:SF7 PROTEIN TAG-278-RELATED PROTEIN FAM184A MONDO|Ensembl=ENSMODG00000004073.2|UniProtKB=A0A5F8G279 A0A5F8G279 PTHR45688:SF1 FAMILY NOT NAMED ETHANOLAMINE-PHOSPHATE PHOSPHO-LYASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 MONDO|Ensembl=ENSMODG00000014782.4|UniProtKB=F7G6X4 F7G6X4 DHX58 PTHR14074:SF7 HELICASE WITH DEATH DOMAIN-RELATED ATP-DEPENDENT RNA HELICASE DHX58 zinc ion binding#GO:0008270;single-stranded RNA binding#GO:0003727;ion binding#GO:0043167;nucleic acid binding#GO:0003676;binding#GO:0005488;small molecule binding#GO:0036094;double-stranded RNA binding#GO:0003725;transition metal ion binding#GO:0046914;RNA binding#GO:0003723;metal ion binding#GO:0046872;cation binding#GO:0043169 regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;intracellular receptor signaling pathway#GO:0030522;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;innate immune response-activating signaling pathway#GO:0002758;antiviral innate immune response#GO:0140374;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to virus#GO:0009615;intracellular signal transduction#GO:0035556;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;response to other organism#GO:0051707;activation of innate immune response#GO:0002218;immune response#GO:0006955;positive regulation of innate immune response#GO:0045089;regulation of innate immune response#GO:0045088;innate immune response#GO:0045087;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;negative regulation of signal transduction#GO:0009968;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;cellular process#GO:0009987;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000037453.1|UniProtKB=A0A5F8GYV2 A0A5F8GYV2 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009416.3|UniProtKB=A0A5F8G2K8 A0A5F8G2K8 FIBIN PTHR31185:SF0 FIN BUD INITIATION FACTOR FIBIN FIN BUD INITIATION FACTOR HOMOLOG MONDO|Ensembl=ENSMODG00000029696.2|UniProtKB=K7E591 K7E591 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003254.2|UniProtKB=F6T1M0 F6T1M0 NEDD8 PTHR10666:SF173 UBIQUITIN UBIQUITIN-LIKE PROTEIN NEDD8 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211 ribosome#GO:0005840;nucleus#GO:0005634;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000002211.4|UniProtKB=F7G3E0 F7G3E0 C4BPB PTHR19325:SF565 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING C4B-BINDING PROTEIN BETA CHAIN complement component#PC00078;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000002073.4|UniProtKB=A0A5F8GZM0 A0A5F8GZM0 GLDN PTHR23192:SF85 OLFACTOMEDIN-RELATED GLIOMEDIN signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000009862.4|UniProtKB=F6VV93 F6VV93 FKBP7 PTHR46222:SF2 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7/14 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000016592.3|UniProtKB=H9H704 H9H704 PTHR23105:SF38 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER NHP2-LIKE PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;rRNA processing#GO:0006364;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular membraneless organelle#GO:0043232;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small-subunit processome#GO:0032040;spliceosomal complex#GO:0005681;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;precatalytic spliceosome#GO:0071011;preribosome#GO:0030684 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000006902.3|UniProtKB=F6PU70 F6PU70 PI15 PTHR10334:SF63 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR 15 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000005285.3|UniProtKB=A0A5F8H303 A0A5F8H303 VPS4B PTHR23074:SF72 AAA DOMAIN-CONTAINING VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4B ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;localization#GO:0051179;protein metabolic process#GO:0019538;cellular localization#GO:0051641;vacuole organization#GO:0007033;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;metabolic process#GO:0008152;intracellular transport#GO:0046907;macromolecule catabolic process#GO:0009057;transport#GO:0006810;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;endosomal transport#GO:0016197;ubiquitin-dependent protein catabolic process#GO:0006511;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000014279.3|UniProtKB=F6X0R8 F6X0R8 POU3F4 PTHR11636:SF83 POU DOMAIN POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000027639.2|UniProtKB=K7E3U9 K7E3U9 PTHR19303:SF26 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013250.4|UniProtKB=F6PHP5 F6PHP5 BCORL1 PTHR24117:SF6 AGAP007537-PB BCL-6 COREPRESSOR-LIKE PROTEIN 1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000018821.4|UniProtKB=F6YYP8 F6YYP8 SETDB1 PTHR46024:SF2 HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS HISTONE-LYSINE N-METHYLTRANSFERASE SETDB1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993 heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000008406.3|UniProtKB=F7BUP6 F7BUP6 CCDC117 PTHR36128:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 117 COILED-COIL DOMAIN-CONTAINING PROTEIN 117 MONDO|Ensembl=ENSMODG00000025387.2|UniProtKB=F6XHW4 F6XHW4 LOC100031303 PTHR26452:SF812 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AC2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000018880.4|UniProtKB=F7DA61 F7DA61 PTHR45813:SF3 IG-LIKE DOMAIN-CONTAINING PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR F1 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;generation of neurons#GO:0048699;neuron development#GO:0048666;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789;synapse assembly#GO:0007416;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component assembly#GO:0022607;nervous system development#GO:0007399;synapse organization#GO:0050808;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;cellular response to stimulus#GO:0051716;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000029178.2|UniProtKB=K7E610 K7E610 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000010591.4|UniProtKB=A0A5F8HDM4 A0A5F8HDM4 PTHR21713:SF38 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED NAC ALPHA DOMAIN CONTAINING protein targeting#GO:0006605;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000012121.4|UniProtKB=F7FU71 F7FU71 STK17B PTHR24342:SF5 SERINE/THREONINE-PROTEIN KINASE 17 SERINE_THREONINE-PROTEIN KINASE 17B catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000049046.1|UniProtKB=F6WZI0 F6WZI0 LOC100022659 PTHR46291:SF8 C2 DOMAIN-CONTAINING PROTEIN C2 CALCIUM DEPENDENT DOMAIN CONTAINING 4A MONDO|Ensembl=ENSMODG00000005970.3|UniProtKB=F6VZG6 F6VZG6 SLC27A4 PTHR43107:SF11 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 4 monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;carboxylic acid transmembrane transporter activity#GO:0046943;ligase activity, forming carbon-sulfur bonds#GO:0016877 monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;establishment of localization#GO:0051234;import into cell#GO:0098657;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;lipid metabolic process#GO:0006629;transport#GO:0006810;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;long-chain fatty acid metabolic process#GO:0001676 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000018468.2|UniProtKB=F7CAK2 F7CAK2 LOC100022818 PTHR26452:SF930 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038451.1|UniProtKB=A0A5F8GDK8 A0A5F8GDK8 RLN3 PTHR20968:SF0 ILGF DOMAIN-CONTAINING PROTEIN RELAXIN-3 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646 MONDO|Ensembl=ENSMODG00000018506.4|UniProtKB=F7B3M9 F7B3M9 GDI2 PTHR11787:SF1 RAB GDP-DISSOCIATION INHIBITOR RAB GDP DISSOCIATION INHIBITOR BETA nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;transport#GO:0006810 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000002838.4|UniProtKB=A0A5F8HHF8 A0A5F8HHF8 UBE4B PTHR13931:SF2 UBIQUITINATION FACTOR E4 UBIQUITIN CONJUGATION FACTOR E4 B acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 catabolic process#GO:0009056;response to stimulus#GO:0050896;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;response to endoplasmic reticulum stress#GO:0034976;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000019030.4|UniProtKB=F7BLI6 F7BLI6 BICRAL PTHR15572:SF2 GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1 BRD4-INTERACTING CHROMATIN-REMODELING COMPLEX-ASSOCIATED PROTEIN-LIKE regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000000309.4|UniProtKB=F6WA41 F6WA41 SUSD2 PTHR13802:SF63 MUCIN 4-RELATED SUSHI DOMAIN-CONTAINING PROTEIN 2 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000015785.4|UniProtKB=A0A5F8GGF6 A0A5F8GGF6 NFKBIL1 PTHR15263:SF2 I-KAPPA-B-LIKE PROTEIN IKBL NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1 molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 B cell activation#P00010>I kappa B#P00392 MONDO|Ensembl=ENSMODG00000021472.4|UniProtKB=F7GDI0 F7GDI0 METTL4 PTHR12829:SF9 N6-ADENOSINE-METHYLTRANSFERASE N(6)-ADENINE-SPECIFIC METHYLTRANSFERASE METTL4 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000028316.2|UniProtKB=K7E3U1 K7E3U1 PTHR46890:SF56 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED OS06G0484800 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000045385.1|UniProtKB=A0A5F8GMB1 A0A5F8GMB1 PTHR23073:SF7 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6A isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;proteasome complex#GO:0000502;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000009156.4|UniProtKB=A0A5F8GBG7 A0A5F8GBG7 PTHR28422:SF1 SIMILAR TO HUMAN CHROMOSOME 15 OPEN READING FRAME 39 SIMILAR TO HUMAN CHROMOSOME 15 OPEN READING FRAME 39 regulation of canonical NF-kappaB signal transduction#GO:0043122;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;negative regulation of defense response#GO:0031348;regulation of cellular process#GO:0050794;negative regulation of inflammatory response#GO:0050728;regulation of signaling#GO:0023051;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000019222.4|UniProtKB=A0A5F8HAM6 A0A5F8HAM6 SPTLC1 PTHR13693:SF2 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 1 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;ceramide metabolic process#GO:0006672;sphingoid biosynthetic process#GO:0046520;primary metabolic process#GO:0044238;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transaminase#PC00216 MONDO|Ensembl=ENSMODG00000019270.4|UniProtKB=F6SI41 F6SI41 ATOH1 PTHR19290:SF82 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED TRANSCRIPTION FACTOR ATOH1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of primary metabolic process#GO:0080090;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell projection organization#GO:0030030;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000042884.1|UniProtKB=A0A5F8GWM3 A0A5F8GWM3 PTHR23268:SF28 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 27 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000049625.1|UniProtKB=A0A5F8GG60 A0A5F8GG60 NUDT2 PTHR21340:SF0 DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL] hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside phosphate biosynthetic process#GO:1901293;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;nucleoside monophosphate metabolic process#GO:0009123;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;ATP biosynthetic process#GO:0006754;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000018002.3|UniProtKB=F7AL68 F7AL68 AICDA PTHR13857:SF10 MRNA EDITING ENZYME SINGLE-STRANDED DNA CYTOSINE DEAMINASE RNA binding#GO:0003723;hydrolase activity#GO:0016787;nucleic acid binding#GO:0003676;binding#GO:0005488;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824 cellular process#GO:0009987;response to biotic stimulus#GO:0009607;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stress#GO:0006950;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;regulation of biological process#GO:0050789;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;biological process involved in interspecies interaction between organisms#GO:0044419;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;RNA modification#GO:0009451;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;base conversion or substitution editing#GO:0016553;RNA metabolic process#GO:0016070;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;response to external stimulus#GO:0009605;defense response#GO:0006952;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;cytidine to uridine editing#GO:0016554;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to external biotic stimulus#GO:0043207;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;macromolecule modification#GO:0043412;response to virus#GO:0009615 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000007246.4|UniProtKB=F6VWW7 F6VWW7 NUP85 PTHR13373:SF21 FROUNT PROTEIN-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP85 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 intracellular protein transport#GO:0006886;metabolic process#GO:0008152;gene expression#GO:0010467;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein transport#GO:0015031;protein import into nucleus#GO:0006606;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931 organelle envelope#GO:0031967;nuclear pore outer ring#GO:0031080;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000024182.2|UniProtKB=F6T4J5 F6T4J5 C15orf62 PTHR15344:SF8 CDC42 EFFECTOR PROTEIN BORG SIMILAR TO HUMAN CHROMOSOME 15 OPEN READING FRAME 62 small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;Rho protein signal transduction#GO:0007266;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of anatomical structure size#GO:0090066;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of actin cytoskeleton organization#GO:0032956;intracellular signaling cassette#GO:0141124;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of cell projection organization#GO:0031346;regulation of cell projection assembly#GO:0060491;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of supramolecular fiber organization#GO:1902903;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273 membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010621.3|UniProtKB=F7DPB1 F7DPB1 PTHR45752:SF50 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1 biological regulation#GO:0065007;response to other organism#GO:0051707;defense response to other organism#GO:0098542;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;immune response#GO:0006955;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;inflammatory response#GO:0006954;immune system process#GO:0002376 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000001565.5|UniProtKB=F7BX50 F7BX50 LRIF1 PTHR16131:SF2 LIGAND-DEPENDENT NUCLEAR RECEPTOR-INTERACTING FACTOR 1 LIGAND-DEPENDENT NUCLEAR RECEPTOR-INTERACTING FACTOR 1 MONDO|Ensembl=ENSMODG00000028106.2|UniProtKB=H9H6T6 H9H6T6 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000044211.1|UniProtKB=A0A5F8GAA9 A0A5F8GAA9 PTHR33588:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000007905.5|UniProtKB=F6YSG1 F6YSG1 PODXL2 PTHR15594:SF1 PODOCALYXIN-LIKE PROTEIN 2 PODOCALYXIN-LIKE PROTEIN 2 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000017712.4|UniProtKB=F7FUJ2 F7FUJ2 HDDC2 PTHR11845:SF13 5'-DEOXYNUCLEOTIDASE HDDC2 5'-DEOXYNUCLEOTIDASE HDDC2 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000014194.4|UniProtKB=A0A5F8GXK8 A0A5F8GXK8 ARHGEF10 PTHR12877:SF14 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 10 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 nuclear division#GO:0000280;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;regulation of actin filament bundle assembly#GO:0032231;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;mitotic nuclear division#GO:0140014;regulation of cellular component organization#GO:0051128;mitotic spindle organization#GO:0007052;regulation of cellular component biogenesis#GO:0044087;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component assembly#GO:0022607;positive regulation of cellular component biogenesis#GO:0044089;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;organelle assembly#GO:0070925;actin filament-based process#GO:0030029;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of supramolecular fiber organization#GO:1902903;mitotic cell cycle#GO:0000278;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of stress fiber assembly#GO:0051492;regulation of actin filament-based process#GO:0032970;spindle organization#GO:0007051;positive regulation of actin filament bundle assembly#GO:0032233;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;mitotic sister chromatid segregation#GO:0000070;positive regulation of cellular process#GO:0048522;mitotic spindle assembly#GO:0090307;regulation of actin filament organization#GO:0110053;biological regulation#GO:0065007 cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000018662.4|UniProtKB=A0A5F8GC01 A0A5F8GC01 LIMS2 PTHR24210:SF10 LIM DOMAIN-CONTAINING PROTEIN LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 2 positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;regulation of response to stimulus#GO:0048583;positive regulation of cell communication#GO:0010647;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cell adhesion#GO:0007155;regulation of signaling#GO:0023051 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;cell-cell junction#GO:0005911;cytoplasm#GO:0005737;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165 cell junction protein#PC00070 Integrin signalling pathway#P00034>PINCH#P00921 MONDO|Ensembl=ENSMODG00000023555.3|UniProtKB=F6Z119 F6Z119 LOC100020073 PTHR24377:SF710 IP01015P-RELATED ZINC FINGER PROTEIN 181-RELATED DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000023112.1|UniProtKB=F7ABF7 F7ABF7 ARL4C PTHR11711:SF119 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4C guanyl nucleotide binding#GO:0019001;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;endocytic recycling#GO:0032456;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 MONDO|Ensembl=ENSMODG00000003618.4|UniProtKB=F7BN42 F7BN42 LRRC39 PTHR45752:SF6 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 39 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014700.4|UniProtKB=F7D3L3 F7D3L3 TNPO3 PTHR12363:SF42 TRANSPORTIN 3 AND IMPORTIN 13 TRANSPORTIN-3 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000038141.1|UniProtKB=A0A5F8GC15 A0A5F8GC15 PTHR24192:SF3 ANKYRIN REPEAT DOMAIN 40 ANKYRIN REPEAT DOMAIN 40 MONDO|Ensembl=ENSMODG00000014256.3|UniProtKB=F6XJK0 F6XJK0 GOT2 PTHR11879:SF58 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;transaminase#PC00216;metabolite interconversion enzyme#PC00262 Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854 MONDO|Ensembl=ENSMODG00000040234.1|UniProtKB=A0A5F8GDQ7 A0A5F8GDQ7 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000042729.1|UniProtKB=A0A5F8H6X5 A0A5F8H6X5 PTHR19446:SF479 REVERSE TRANSCRIPTASES RNA-DIRECTED DNA POLYMERASE viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000021542.3|UniProtKB=F7DZP8 F7DZP8 OPA3 PTHR12499:SF30 OPTIC ATROPHY 3 PROTEIN OPA3 OPTIC ATROPHY 3 PROTEIN nervous system process#GO:0050877;neuromuscular process#GO:0050905;multicellular organismal process#GO:0032501;system process#GO:0003008 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000002989.4|UniProtKB=F6Q4F7 F6Q4F7 C3orf49 PTHR36473:SF1 CHROMOSOME 3 OPEN READING FRAME 49 GENE 11100-RELATED MONDO|Ensembl=ENSMODG00000021099.4|UniProtKB=F6UIC5 F6UIC5 MED14 PTHR12809:SF2 MEDIATOR COMPLEX SUBUNIT MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 14 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000040587.1|UniProtKB=A0A5F8HEV3 A0A5F8HEV3 DHRSX PTHR24320:SF264 RETINOL DEHYDROGENASE POLYPRENOL DEHYDROGENASE oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000003720.4|UniProtKB=F7E9J9 F7E9J9 ATP4B PTHR11523:SF11 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671 cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion import across plasma membrane#GO:0099587;export from cell#GO:0140352;metal ion transport#GO:0030001;homeostatic process#GO:0042592;import across plasma membrane#GO:0098739;inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;potassium ion homeostasis#GO:0055075 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;ATPase dependent transmembrane transport complex#GO:0098533;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cation-transporting ATPase complex#GO:0090533 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000009294.4|UniProtKB=K7DZB6 K7DZB6 MEDAG PTHR33769:SF3 TESTIS-EXPRESSED PROTEIN 26 ISOFORM X3 MESENTERIC ESTROGEN-DEPENDENT ADIPOGENESIS PROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000006490.4|UniProtKB=A0A5F8GQC1 A0A5F8GQC1 PTHR18905:SF12 NINEIN NINEIN-LIKE PROTEIN microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule anchoring at microtubule organizing center#GO:0072393;microtubule cytoskeleton organization#GO:0000226;microtubule anchoring#GO:0034453;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 PDGF signaling pathway#P00047>GSK3#P01153 MONDO|Ensembl=ENSMODG00000020343.4|UniProtKB=F7FWK6 F7FWK6 VPS37C PTHR13678:SF8 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37C catabolic process#GO:0009056;protein localization to organelle#GO:0033365;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;localization#GO:0051179;protein metabolic process#GO:0019538;protein localization to vacuole#GO:0072665;localization within membrane#GO:0051668;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;macromolecule localization#GO:0033036;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;cellular localization#GO:0051641;protein transport#GO:0015031;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;establishment of protein localization to membrane#GO:0090150;protein targeting to vacuole#GO:0006623;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;metabolic process#GO:0008152;protein targeting to membrane#GO:0006612;macromolecule catabolic process#GO:0009057;intracellular protein transport#GO:0006886 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;ESCRT I complex#GO:0000813;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000007389.4|UniProtKB=F6ZMN3 F6ZMN3 ZNF750 PTHR14678:SF1 PROLINE-RICH PROTEIN 35-RELATED ZINC FINGER PROTEIN 750 nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;epidermis development#GO:0008544;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;tissue development#GO:0009888;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000044487.1|UniProtKB=A0A5F8GNU2 A0A5F8GNU2 LEPROT PTHR12050:SF3 LEPTIN RECEPTOR-RELATED LEPTIN RECEPTOR GENE-RELATED PROTEIN intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482 vesicle membrane#GO:0012506;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015443.4|UniProtKB=F6S4I5 F6S4I5 AMDHD2 PTHR11113:SF14 N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE deacetylase activity#GO:0019213;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;deacylase activity#GO:0160215;catalytic activity#GO:0003824 metabolic process#GO:0008152;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;catabolic process#GO:0009056;amino sugar catabolic process#GO:0046348;amino sugar metabolic process#GO:0006040;carbohydrate derivative catabolic process#GO:1901136 deacetylase#PC00087;metabolite interconversion enzyme#PC00262 N-acetylglucosamine metabolism#P02756>N-acetylglucosamine-6-phosphate deacetylase#P03036 MONDO|Ensembl=ENSMODG00000045941.1|UniProtKB=A0A5F8GHM4 A0A5F8GHM4 PTHR23232:SF163 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018741.3|UniProtKB=F7EFK1 F7EFK1 RNF115 PTHR15710:SF16 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF115 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968;regulation of response to external stimulus#GO:0032101;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of innate immune response#GO:0045088;macromolecule metabolic process#GO:0043170;regulation of ERBB signaling pathway#GO:1901184;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;catabolic process#GO:0009056;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000007814.3|UniProtKB=F7ETU4 F7ETU4 C10orf88 PTHR14787:SF1 C10ORF188 FAMILY MEMBER ATPASE PAAT ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000000665.4|UniProtKB=F6SBD5 F6SBD5 HIPK1 PTHR24058:SF43 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cellular response to stress#GO:0033554;signal transduction by p53 class mediator#GO:0072331;intracellular signal transduction#GO:0035556;smoothened signaling pathway#GO:0007224;intrinsic apoptotic signaling pathway#GO:0097193;cell communication#GO:0007154;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;cell surface receptor signaling pathway#GO:0007166;DNA damage response#GO:0006974;apoptotic signaling pathway#GO:0097190;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nuclear body#GO:0016604;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000017717.3|UniProtKB=F7FHI4 F7FHI4 UTP11 PTHR12838:SF0 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;small-subunit processome#GO:0032040;organelle lumen#GO:0043233 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000005460.4|UniProtKB=F7CGN7 F7CGN7 SERPINB10 PTHR11461:SF175 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B10 enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000007930.4|UniProtKB=F7G964 F7G964 PTHR10418:SF2 SECURIN-3 SECURIN MONDO|Ensembl=ENSMODG00000011495.3|UniProtKB=F6V1Q9 F6V1Q9 MYL2 PTHR23049:SF9 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 2, VENTRICULAR_CARDIAC MUSCLE ISOFORM cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872 cellular process#GO:0009987;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;heart development#GO:0007507;cell fate specification#GO:0001708;muscle contraction#GO:0006936;developmental process#GO:0032502;system process#GO:0003008;heart contraction#GO:0060047;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;heart process#GO:0003015;muscle cell differentiation#GO:0042692;muscle system process#GO:0003012;striated muscle contraction#GO:0006941;muscle structure development#GO:0061061;circulatory system development#GO:0072359;cell differentiation#GO:0030154;cardiac muscle contraction#GO:0060048;animal gross anatomical part developmental process#GO:0160108;circulatory system process#GO:0003013;system development#GO:0048731;cell fate commitment#GO:0045165;anatomical structure development#GO:0048856 myosin complex#GO:0016459;contractile muscle fiber#GO:0043292;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000027664.2|UniProtKB=K7E0A6 K7E0A6 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000009138.4|UniProtKB=F7B100 F7B100 MLLT10 PTHR13793:SF93 PHD FINGER PROTEINS PROTEIN AF-10 histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000002071.4|UniProtKB=F6UZX8 F6UZX8 ALDH1L2 PTHR11699:SF131 ALDEHYDE DEHYDROGENASE-RELATED MITOCHONDRIAL 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;tetrahydrofolate metabolic process#GO:0046653 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 MONDO|Ensembl=ENSMODG00000011158.4|UniProtKB=F7AN33 F7AN33 BMPR1A PTHR23255:SF50 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1A catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transforming growth factor beta receptor activity#GO:0005024;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;transmembrane signaling receptor activity#GO:0004888 enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of biological process#GO:0050789;dorsal/ventral pattern formation#GO:0009953;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;regionalization#GO:0003002;multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 serine/threonine protein kinase receptor#PC00205 Gonadotropin-releasing hormone receptor pathway#P06664>BMPR-IA/IB/II#P06740;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442 MONDO|Ensembl=ENSMODG00000040635.1|UniProtKB=A0A5F8GSY8 A0A5F8GSY8 LOC103093866 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000023737.3|UniProtKB=F6X7Z5 F6X7Z5 LOC100017222 PTHR24377:SF1029 IP01015P-RELATED ZINC FINGER PROTEIN 135 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014943.4|UniProtKB=F7FIE3 F7FIE3 PSIP1 PTHR12550:SF42 HEPATOMA-DERIVED GROWTH FACTOR-RELATED PC4 AND SFRS1-INTERACTING PROTEIN cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000002070.4|UniProtKB=F6UZY8 F6UZY8 EIF2D PTHR12217:SF4 EUKARYOTIC TRANSLATION INITIATION FACTOR 2D EUKARYOTIC TRANSLATION INITIATION FACTOR 2D translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000048365.1|UniProtKB=A0A5F8GCM3 A0A5F8GCM3 PTHR31594:SF14 AIG1-TYPE G DOMAIN-CONTAINING PROTEIN FIBRONECTIN TYPE III AND SPRY DOMAIN CONTAINING 1 LIKE MONDO|Ensembl=ENSMODG00000012447.2|UniProtKB=F6PJA5 F6PJA5 LOC100010080 PTHR26453:SF627 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000044182.1|UniProtKB=A0A5F8HBF2 A0A5F8HBF2 PTHR24366:SF172 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LRRCT DOMAIN-CONTAINING PROTEIN immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000012226.4|UniProtKB=F6Z6Q3 F6Z6Q3 GPATCH1 PTHR13384:SF19 G PATCH DOMAIN-CONTAINING PROTEIN 1 G PATCH DOMAIN-CONTAINING PROTEIN 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000018598.4|UniProtKB=F7BQ34 F7BQ34 MRPS22 PTHR13071:SF4 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S22 SMALL RIBOSOMAL SUBUNIT PROTEIN MS22 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000010040.4|UniProtKB=A0A5F8GEJ8 A0A5F8GEJ8 PTHR18952:SF134 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 15 catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000023181.4|UniProtKB=A0A5F8GIN8 A0A5F8GIN8 KCTD7 PTHR14499:SF122 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD7 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of membrane potential#GO:0042391;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000041176.1|UniProtKB=K7DZA5 K7DZA5 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000036371.1|UniProtKB=F7A7Q4 F7A7Q4 LOC100030411 PTHR26452:SF99 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000018302.3|UniProtKB=F6PVK8 F6PVK8 FGF23 PTHR11486:SF69 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 23 receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;fibroblast growth factor receptor binding#GO:0005104;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 nervous system development#GO:0007399;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;system development#GO:0048731;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000010407.2|UniProtKB=F7A787 F7A787 GRINA PTHR23291:SF16 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 1 calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;endoplasmic reticulum unfolded protein response#GO:0030968;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;cellular response to topologically incorrect protein#GO:0035967;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of apoptotic process#GO:0042981;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;negative regulation of neuron apoptotic process#GO:0043524;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;response to unfolded protein#GO:0006986;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 ion channel#PC00133;transporter#PC00227 Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060 MONDO|Ensembl=ENSMODG00000036893.1|UniProtKB=A0A5F8HEP9 A0A5F8HEP9 FNDC11 PTHR14537:SF0 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 11 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 11 MONDO|Ensembl=ENSMODG00000009288.3|UniProtKB=F6YXN6 F6YXN6 CPLX3 PTHR16705:SF5 COMPLEXIN COMPLEXIN-3 protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488 neurotransmitter transport#GO:0006836;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic signaling#GO:0099536;regulation of transport#GO:0051049;regulation of localization#GO:0032879;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;regulated exocytosis#GO:0045055;signaling#GO:0023052;export from cell#GO:0140352;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;signal release#GO:0023061;trans-synaptic signaling#GO:0099537 membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;terminal bouton#GO:0043195;distal axon#GO:0150034;neuron projection terminus#GO:0044306;cell projection#GO:0042995;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;synapse#GO:0045202;axon#GO:0030424;intracellular anatomical structure#GO:0005622;presynapse#GO:0098793;neuron projection#GO:0043005;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000002284.4|UniProtKB=F7CVL5 F7CVL5 HDC PTHR11999:SF68 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE HISTIDINE DECARBOXYLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831 biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;amine metabolic process#GO:0009308;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;lyase#PC00144 CCKR signaling map#P06959>HDC#G07262;CCKR signaling map#P06959>HDC#G06969;Histamine synthesis#P04387>Histidine decarboxylase#P04493 MONDO|Ensembl=ENSMODG00000047836.1|UniProtKB=A0A5F8H6W5 A0A5F8H6W5 LOC100617005 PTHR38503:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 1 SMALL INTEGRAL MEMBRANE PROTEIN 1 homeostasis of number of cells#GO:0048872;developmental process#GO:0032502;immune system process#GO:0002376;multicellular organismal-level homeostasis#GO:0048871;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;erythrocyte differentiation#GO:0030218;cellular process#GO:0009987;cell development#GO:0048468;homeostatic process#GO:0042592;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000008497.4|UniProtKB=F7FTS3 F7FTS3 GAL3ST3 PTHR14647:SF83 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSE-3-O-SULFOTRANSFERASE 3 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220 MONDO|Ensembl=ENSMODG00000046733.1|UniProtKB=A0A5F8G2Q5 A0A5F8G2Q5 VTA1 PTHR46009:SF1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;late endosome to vacuole transport#GO:0045324;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197 late endosome#GO:0005770;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000003697.2|UniProtKB=F7F5D3 F7F5D3 PTHR47958:SF26 ATP-DEPENDENT RNA HELICASE DBP3 EUKARYOTIC INITIATION FACTOR 4A-III catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;organelle lumen#GO:0043233 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000020280.2|UniProtKB=F7C0G7 F7C0G7 NIM1K PTHR24343:SF0 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE NIM1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000016748.2|UniProtKB=F6YL87 F6YL87 JMJD8 PTHR12480:SF35 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD JMJC DOMAIN-CONTAINING PROTEIN 8 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000008729.4|UniProtKB=F6PUC5 F6PUC5 CYBRD1 PTHR10106:SF12 CYTOCHROME B561-RELATED PLASMA MEMBRANE ASCORBATE-DEPENDENT REDUCTASE CYBRD1 oxidoreductase activity#GO:0016491;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity, acting on metal ions#GO:0016722;catalytic activity#GO:0003824;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;carbohydrate homeostasis#GO:0033500;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592 cell periphery#GO:0071944;brush border#GO:0005903;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;brush border membrane#GO:0031526;plasma membrane region#GO:0098590;apical part of cell#GO:0045177;cluster of actin-based cell projections#GO:0098862;cell projection membrane#GO:0031253 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000040576.1|UniProtKB=A0A5F8H4I2 A0A5F8H4I2 ALG2 PTHR45918:SF1 ALPHA-1,3/1,6-MANNOSYLTRANSFERASE ALG2 ALPHA-1,3_1,6-MANNOSYLTRANSFERASE ALG2 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000007050.4|UniProtKB=K7E0I7 K7E0I7 NAGA PTHR11452:SF25 ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE ALPHA-N-ACETYLGALACTOSAMINIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 galactosidase#PC00104;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000017677.4|UniProtKB=F7GFR6 F7GFR6 RSPO3 PTHR46987:SF1 NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN R-SPONDIN-3 G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000008756.4|UniProtKB=F6PRN4 F6PRN4 LOC100617762 PTHR26453:SF117 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2C3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040938.1|UniProtKB=A0A5F8HAC1 A0A5F8HAC1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000021191.4|UniProtKB=F7FR73 F7FR73 SGPP2 PTHR14969:SF14 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE SPHINGOSINE-1-PHOSPHATE PHOSPHATASE 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 alcohol metabolic process#GO:0006066;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;dephosphorylation#GO:0016311;primary metabolic process#GO:0044238;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;small molecule metabolic process#GO:0044281 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000017200.4|UniProtKB=F6XFL1 F6XFL1 NDOR1 PTHR19384:SF10 NITRIC OXIDE SYNTHASE-RELATED NADPH-DEPENDENT DIFLAVIN OXIDOREDUCTASE 1 ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;binding#GO:0005488;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000028242.2|UniProtKB=F6V0G8 F6V0G8 LOC103101465 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020300.4|UniProtKB=F7BFH7 F7BFH7 PTHR22797:SF36 CARD6/NUCLEOLAR PROTEIN 3 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 6 MONDO|Ensembl=ENSMODG00000002023.4|UniProtKB=F6QWP3 F6QWP3 PTHR24089:SF196 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL ADENYL NUCLEOTIDE ANTIPORTER SLC25A23 phosphate transmembrane transporter activity#GO:0005315;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;purine nucleotide transmembrane transporter activity#GO:0015216;active transmembrane transporter activity#GO:0022804 nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;carbohydrate derivative transport#GO:1901264;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;mitochondrial calcium ion transmembrane transport#GO:0006851;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;transport#GO:0006810 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000009524.2|UniProtKB=F7EUZ2 F7EUZ2 N4BP2L1 PTHR13308:SF5 NEDD4-BINDING PROTEIN 2-LIKE 1 NEDD4-BINDING PROTEIN 2-LIKE 1 MONDO|Ensembl=ENSMODG00000048340.1|UniProtKB=A0A5F8G3T7 A0A5F8G3T7 PTHR13947:SF48 GNAT FAMILY N-ACETYLTRANSFERASE N-ACETYLTRANSFERASE 8-RELATED N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000001364.3|UniProtKB=F7FVZ4 F7FVZ4 WDR77 PTHR46853:SF3 METHYLOSOME PROTEIN 50 METHYLOSOME PROTEIN WDR77 organelle#GO:0043226;methyltransferase complex#GO:0034708;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000002997.3|UniProtKB=F6Q3X0 F6Q3X0 KYNU PTHR14084:SF0 KYNURENINASE KYNURENINASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000007725.4|UniProtKB=F7EUH4 F7EUH4 WBP2 PTHR31606:SF4 WW DOMAIN BINDING PROTEIN 2, ISOFORM E WW DOMAIN-BINDING PROTEIN 2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;chromatin DNA binding#GO:0031490 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000046311.1|UniProtKB=A0A5F8H7P0 A0A5F8H7P0 PTHR10553:SF2 SMALL NUCLEAR RIBONUCLEOPROTEIN SMALL NUCLEAR RIBONUCLEOPROTEIN G RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398 P granule#GO:0043186;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;small nuclear ribonucleoprotein complex#GO:0030532;SMN-Sm protein complex#GO:0034719;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;U2-type spliceosomal complex#GO:0005684;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U12-type spliceosomal complex#GO:0005689;U1 snRNP#GO:0005685;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;precatalytic spliceosome#GO:0071011;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;U2-type prespliceosome#GO:0071004;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000046540.1|UniProtKB=A0A5F8GVP1 A0A5F8GVP1 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018850.4|UniProtKB=F7DWE4 F7DWE4 PTHR24300:SF302 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 tetrapyrrole binding#GO:0046906;binding#GO:0005488;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000039781.1|UniProtKB=A0A5F8GUW3 A0A5F8GUW3 LOC100617634 PTHR48018:SF5 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8A1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005624.2|UniProtKB=F7CFH9 F7CFH9 POLR3F PTHR12780:SF1 RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC6 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000010580.4|UniProtKB=A0A5F8GXK5 A0A5F8GXK5 PHACTR1 PTHR12751:SF6 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 1 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;contractile actin filament bundle assembly#GO:0030038;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;supramolecular fiber organization#GO:0097435;stress fiber assembly#GO:0043149;actin filament-based process#GO:0030029;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;cellular component organization#GO:0016043 phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000006557.2|UniProtKB=F7BUV5 F7BUV5 EPOR PTHR23037:SF28 CYTOKINE RECEPTOR ERYTHROPOIETIN RECEPTOR signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001574.4|UniProtKB=A0A5F8GZ28 A0A5F8GZ28 RBM26 PTHR14398:SF2 RNA RECOGNITION RRM/RNP DOMAIN RNA-BINDING PROTEIN 26 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000047179.1|UniProtKB=A0A5F8G3H8 A0A5F8G3H8 PTHR44427:SF13 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 4-RELATED cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000024396.1|UniProtKB=F6Z4A1 F6Z4A1 GPR20 PTHR24232:SF7 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 20 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038227.1|UniProtKB=A0A5F8GB72 A0A5F8GB72 DOC2B PTHR45729:SF9 RABPHILIN, ISOFORM A DOUBLE C2-LIKE DOMAIN-CONTAINING PROTEIN BETA trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;regulation of secretion#GO:0051046;regulation of exocytosis#GO:0017157;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of secretion#GO:0051047;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;regulation of organelle organization#GO:0033043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;export from cell#GO:0140352;regulated exocytosis#GO:0045055;vesicle-mediated transport in synapse#GO:0099003;regulation of localization#GO:0032879;exocytosis#GO:0006887;regulation of transport#GO:0051049;positive regulation of vesicle fusion#GO:0031340;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;synaptic vesicle exocytosis#GO:0016079;positive regulation of secretion by cell#GO:1903532;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000002133.4|UniProtKB=A0A5F8H1G9 A0A5F8H1G9 PTHR23333:SF16 UBX DOMAIN CONTAINING PROTEIN UBX DOMAIN-CONTAINING PROTEIN 2A binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 establishment of organelle localization#GO:0051656;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;spindle localization#GO:0051653;cellular localization#GO:0051641;regulation of cellular response to stress#GO:0080135;establishment or maintenance of cell polarity#GO:0007163;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;proteasomal protein catabolic process#GO:0010498;cytoskeleton organization#GO:0007010;establishment of mitotic spindle localization#GO:0040001;regulation of protein metabolic process#GO:0051246;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component organization or biogenesis#GO:0071840;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;mitotic cell cycle#GO:0000278;catabolic process#GO:0009056;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteasomal protein catabolic process#GO:1901799;regulation of ERAD pathway#GO:1904292;primary metabolic process#GO:0044238;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;regulation of response to endoplasmic reticulum stress#GO:1905897;modification-dependent protein catabolic process#GO:0019941;establishment of cell polarity#GO:0030010;protein metabolic process#GO:0019538;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;organelle localization#GO:0051640;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;establishment of spindle localization#GO:0051293;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;mitotic cell cycle process#GO:1903047;regulation of response to stress#GO:0080134;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000027867.2|UniProtKB=A0A5F8GV22 A0A5F8GV22 PTHR24100:SF149 BUTYROPHILIN BG ANTIGEN 1, MHCB REGION-RELATED signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000024260.2|UniProtKB=F6ZU44 F6ZU44 LOC100013789 PTHR16231:SF5 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 6 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;tumor necrosis factor-mediated signaling pathway#GO:0033209;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;cellular process#GO:0009987;response to tumor necrosis factor#GO:0034612;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000047936.1|UniProtKB=A0A5F8G7R3 A0A5F8G7R3 TMEM160 PTHR16236:SF0 TRANSMEMBRANE PROTEIN 160 TRANSMEMBRANE PROTEIN 160 MONDO|Ensembl=ENSMODG00000010209.4|UniProtKB=F6SAT6 F6SAT6 UBE2A PTHR24067:SF243 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 A acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000002375.3|UniProtKB=A0A5F8H3H2 A0A5F8H3H2 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;immune response-regulating signaling pathway#GO:0002764;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000040993.1|UniProtKB=A0A5F8H7T7 A0A5F8H7T7 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000042277.1|UniProtKB=A0A5F8GT62 A0A5F8GT62 FASTKD5 PTHR21228:SF70 FAST LEU-RICH DOMAIN-CONTAINING NON-CANONICAL PRE-MRNAS ENDONUCLEASE FASTKD5, MITOCHONDRIAL RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;regulation of RNA stability#GO:0043487;mitochondrial RNA metabolic process#GO:0000959;regulation of RNA metabolic process#GO:0051252;mitochondrial gene expression#GO:0140053;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000003211.4|UniProtKB=A0A5F8GR59 A0A5F8GR59 PROX1 PTHR12198:SF6 HOMEOBOX PROTEIN PROSPERO/PROX-1/CEH-26 PROSPERO HOMEOBOX PROTEIN 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000000102.4|UniProtKB=F6YC85 F6YC85 PLA2G12B PTHR12824:SF2 GROUP XII SECRETORY PHOSPHOLIPASE A2 FAMILY MEMBER GROUP XIIB SECRETORY PHOSPHOLIPASE A2-LIKE PROTEIN cholesterol homeostasis#GO:0042632;homeostatic process#GO:0042592;triglyceride homeostasis#GO:0070328;lipid homeostasis#GO:0055088;chemical homeostasis#GO:0048878 hydrolase#PC00121;phospholipase#PC00186;lipase#PC00143 MONDO|Ensembl=ENSMODG00000014097.4|UniProtKB=F7CEW7 F7CEW7 WDR91 PTHR13083:SF3 WD REPEAT-CONTAINING PROTEIN 91 WD REPEAT-CONTAINING PROTEIN 91 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;early endosome to late endosome transport#GO:0045022;vesicle-mediated transport#GO:0016192 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;early endosome membrane#GO:0031901;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000041414.1|UniProtKB=A0A5F8GQL9 A0A5F8GQL9 PTHR23304:SF189 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000005279.5|UniProtKB=F7E6W5 F7E6W5 MMP14 PTHR10201:SF24 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-14 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;developmental process#GO:0032502;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;gene expression#GO:0010467;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;skeletal system development#GO:0001501;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;system development#GO:0048731;external encapsulating structure organization#GO:0045229;proteolysis#GO:0006508;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;catabolic process#GO:0009056;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;zymogen activation#GO:0031638 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 metalloprotease#PC00153 Gonadotropin-releasing hormone receptor pathway#P06664>MT1-MMP#P06716;Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 MONDO|Ensembl=ENSMODG00000003800.3|UniProtKB=A0A5F8GQD1 A0A5F8GQD1 ESAM PTHR44549:SF1 ENDOTHELIAL CELL-SELECTIVE ADHESION MOLECULE ENDOTHELIAL CELL-SELECTIVE ADHESION MOLECULE cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609 anchoring junction#GO:0070161;adherens junction#GO:0005912;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000049857.1|UniProtKB=A0A5F8GQD3 A0A5F8GQD3 TNFAIP1 PTHR11145:SF17 BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER BTB_POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 2 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;negative regulation of response to stimulus#GO:0048585;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of small GTPase mediated signal transduction#GO:0051056;cellular process#GO:0009987;protein ubiquitination#GO:0016567;negative regulation of signal transduction#GO:0009968;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Rho protein signal transduction#GO:0035023 intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000029198.2|UniProtKB=K7E1L9 K7E1L9 PTHR39232:SF1 TESTIS-EXPRESSED PROTEIN 50 TESTIS-EXPRESSED PROTEIN 50 MONDO|Ensembl=ENSMODG00000010578.4|UniProtKB=A0A5F8G8G8 A0A5F8G8G8 NUP35 PTHR21527:SF6 NUCLEOPORIN NUP35 NUCLEOPORIN NUP35 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198;lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear pore organization#GO:0006999;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nucleocytoplasmic transport#GO:0006913;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;organelle organization#GO:0006996;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;nucleus organization#GO:0006997;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622 transporter#PC00227 MONDO|Ensembl=ENSMODG00000028606.2|UniProtKB=A0A5F8HGN8 A0A5F8HGN8 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010743.3|UniProtKB=A0A5F8GPF4 A0A5F8GPF4 TRIP4 PTHR12963:SF6 THYROID RECEPTOR INTERACTING PROTEIN RELATED ACTIVATING SIGNAL COINTEGRATOR 1 modification-dependent protein catabolic process#GO:0019941;rescue of stalled cytosolic ribosome#GO:0072344;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cytoplasmic translation#GO:0002181;catabolic process#GO:0009056;protein biosynthetic process#GO:0160307;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;translation#GO:0006412;organelle disassembly#GO:1903008;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organelle organization#GO:0006996;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;gene expression#GO:0010467;metabolic process#GO:0008152;translational elongation#GO:0006414;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000004882.4|UniProtKB=F7C2P0 F7C2P0 ACHE PTHR43918:SF11 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 esterase#PC00097 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080;Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093 MONDO|Ensembl=ENSMODG00000010274.4|UniProtKB=F6VPB7 F6VPB7 ERH PTHR12373:SF0 ENHANCER OF RUDIMENTARY ERH ENHANCER OF RUDIMENTARY HOMOLOG molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 regulation of chromatin organization#GO:1902275;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nuclear mRNA surveillance#GO:0071028;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;regulation of cellular component organization#GO:0051128;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000020189.3|UniProtKB=F7G8K1 F7G8K1 OR5A2 PTHR26452:SF176 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5A2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000041060.1|UniProtKB=A0A5F8GXC3 A0A5F8GXC3 LOC100617847 PTHR24381:SF434 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 436 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000038256.1|UniProtKB=A0A5F8HK42 A0A5F8HK42 PTHR31450:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 19 LRRC19 FAMILY MEMBER TYPE III ENDOSOME MEMBRANE PROTEIN TEMP MONDO|Ensembl=ENSMODG00000004659.4|UniProtKB=F6UMU5 F6UMU5 SSUH2 PTHR15852:SF54 PLASTID TRANSCRIPTIONALLY ACTIVE PROTEIN PROTEIN SSUH2 HOMOLOG MONDO|Ensembl=ENSMODG00000015808.4|UniProtKB=F7FE98 F7FE98 GPR149 PTHR24229:SF32 NEUROPEPTIDES RECEPTOR G PROTEIN-COUPLED RECEPTOR 149-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;neuropeptide signaling pathway#GO:0007218 plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000126.4|UniProtKB=A0A5F8H8F7 A0A5F8H8F7 ITPKA PTHR12400:SF55 INOSITOL POLYPHOSPHATE KINASE INOSITOL-TRISPHOSPHATE 3-KINASE A phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 kinase#PC00137 MONDO|Ensembl=ENSMODG00000008884.4|UniProtKB=F7G1H8 F7G1H8 TRIM58 PTHR24103:SF393 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM58 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 response to biotic stimulus#GO:0009607;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;immune system process#GO:0002376 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000019130.4|UniProtKB=F7EUL3 F7EUL3 SLFN14 PTHR12155:SF50 SCHLAFEN MGC83227 PROTEIN endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000000761.2|UniProtKB=A0A5F8HB46 A0A5F8HB46 SIX2 PTHR10390:SF77 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;kidney development#GO:0001822;renal system development#GO:0072001;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000023267.2|UniProtKB=F6WR39 F6WR39 BHLHE23 PTHR19290:SF53 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 23 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of primary metabolic process#GO:0080090;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell projection organization#GO:0030030;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000008757.3|UniProtKB=F6PRP1 F6PRP1 ARHGEF33 PTHR46944:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 33 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 33 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000017291.4|UniProtKB=F6SM08 F6SM08 ORC5 PTHR12705:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 binding#GO:0005488;DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565 DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular process#GO:0009987 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear origin of replication recognition complex#GO:0005664;origin recognition complex#GO:0000808;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232 replication origin binding protein#PC00199 MONDO|Ensembl=ENSMODG00000002175.4|UniProtKB=F7GEH2 F7GEH2 GOLGA5 PTHR13815:SF7 GOLGIN-84 GOLGIN SUBFAMILY A MEMBER 5 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;retrograde transport, vesicle recycling within Golgi#GO:0000301;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi stack#GO:0005795;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;Golgi cisterna#GO:0031985;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000023265.3|UniProtKB=F7GGK9 F7GGK9 PTHR15107:SF3 RETINOBLASTOMA BINDING PROTEIN 8 RBBP8 N-TERMINAL-LIKE PROTEIN DNA binding#GO:0003677;damaged DNA binding#GO:0003684;binding#GO:0005488;nucleic acid binding#GO:0003676 DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;DNA double-strand break processing#GO:0000729;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;double-strand break repair via single-strand annealing#GO:0045002;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000023817.2|UniProtKB=F6QKU6 F6QKU6 PTHR48001:SF52 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014239.5|UniProtKB=F6T918 F6T918 SLC39A7 PTHR16950:SF25 ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4 ZINC TRANSPORTER SLC39A7 metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385 cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;zinc ion transmembrane transport#GO:0071577;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000015425.3|UniProtKB=F6SMN2 F6SMN2 PBK PTHR43289:SF14 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED LYMPHOKINE-ACTIVATED KILLER T-CELL-ORIGINATED PROTEIN KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000020520.3|UniProtKB=F7ENS8 F7ENS8 DTHD1 PTHR28336:SF4 BA1-643 DEATH DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000001263.4|UniProtKB=A0A5F8G834 A0A5F8G834 PTHR45702:SF1 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER ADAM10 ENDOPEPTIDASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;Notch signaling pathway#GO:0007219;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;signal transduction#GO:0007165;biological regulation#GO:0065007;membrane protein ectodomain proteolysis#GO:0006509;proteolysis#GO:0006508;protein metabolic process#GO:0019538;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000009685.3|UniProtKB=F6YBK3 F6YBK3 PTHR13410:SF9 PROTEIN PBDC1 PROTEIN PBDC1 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 MONDO|Ensembl=ENSMODG00000000305.4|UniProtKB=A0A5F8HHD7 A0A5F8HHD7 LOC100011334 PTHR11199:SF2 STROMAL ANTIGEN COHESIN SUBUNIT SA chromatin binding#GO:0003682;binding#GO:0005488 cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cohesin complex#GO:0008278;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000016635.4|UniProtKB=A0A5F8GPS1 A0A5F8GPS1 LOC130453478 PTHR11442:SF41 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT ZETA tetrapyrrole binding#GO:0046906;heme binding#GO:0020037;binding#GO:0005488;molecular carrier activity#GO:0140104 transport#GO:0006810;developmental process#GO:0032502;multicellular organismal-level homeostasis#GO:0048871;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;cellular process#GO:0009987;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;homeostasis of number of cells#GO:0048872;immune system process#GO:0002376;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;localization#GO:0051179;cell development#GO:0048468;homeostatic process#GO:0042592;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 globin#PC00107;transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000028171.2|UniProtKB=K7E162 K7E162 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000007174.3|UniProtKB=F6RC94 F6RC94 MED6 PTHR13104:SF0 MED-6-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 6 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000004356.4|UniProtKB=F6T3S9 F6T3S9 GBX1 PTHR24334:SF2 HOMEOBOX PROTEIN GBX HOMEOBOX PROTEIN GBX-1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000010311.4|UniProtKB=F6W221 F6W221 LAMP2 PTHR11506:SF6 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 2 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;protein targeting to vacuole#GO:0006623;response to stress#GO:0006950;establishment of protein localization#GO:0045184;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lysosomal transport#GO:0007041;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;cellular component disassembly#GO:0022411;cellular localization#GO:0051641;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;protein localization to lysosome#GO:0061462;cellular component organization#GO:0016043;response to stimulus#GO:0050896;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;cellular response to starvation#GO:0009267;intracellular transport#GO:0046907;autophagosome maturation#GO:0097352;vacuolar transport#GO:0007034;cellular response to nutrient levels#GO:0031669;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;response to nutrient levels#GO:0031667;macroautophagy#GO:0016236;protein localization to vacuole#GO:0072665;localization#GO:0051179;protein metabolic process#GO:0019538;response to starvation#GO:0042594;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;protein-containing complex disassembly#GO:0032984 autophagosome#GO:0005776;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000011876.3|UniProtKB=F7G2Q5 F7G2Q5 C19orf53 PTHR16967:SF1 LEYDIG CELL TUMOR 10 KDA PROTEIN HOMOLOG LEYDIG CELL TUMOR 10 KDA PROTEIN HOMOLOG biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of cell population proliferation#GO:0008284 MONDO|Ensembl=ENSMODG00000004220.3|UniProtKB=F6X8U4 F6X8U4 CYBA PTHR15168:SF0 CYTOCHROME B-245 LIGHT CHAIN CYTOCHROME B-245 LIGHT CHAIN oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664 immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;superoxide metabolic process#GO:0006801;cellular process#GO:0009987;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542 catalytic complex#GO:1902494;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204 MONDO|Ensembl=ENSMODG00000009823.4|UniProtKB=F6RX51 F6RX51 PRKRA PTHR46205:SF2 LOQUACIOUS, ISOFORM B INTERFERON-INDUCIBLE DOUBLE-STRANDED RNA-DEPENDENT PROTEIN KINASE ACTIVATOR A binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;siRNA processing#GO:0030422;regulation of gene silencing by regulatory ncRNA#GO:0060966;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 Apoptosis signaling pathway#P00006>PACT#P00280 MONDO|Ensembl=ENSMODG00000050797.1|UniProtKB=A0A5F8GB75 A0A5F8GB75 PTHR38498:SF1 TRANSMEMBRANE PROTEIN 191B-RELATED TRANSMEMBRANE PROTEIN 191C MONDO|Ensembl=ENSMODG00000010945.5|UniProtKB=F7EP22 F7EP22 DSG2 PTHR24025:SF1 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-2 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 cadherin#PC00057 MONDO|Ensembl=ENSMODG00000001986.4|UniProtKB=F6RIB0 F6RIB0 PTHR45847:SF3 FATTY ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;amidase activity#GO:0004040;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid catabolic process#GO:0072329;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;fatty acid catabolic process#GO:0009062;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629 hydrolase#PC00121 Anandamide degradation#P05728>FAAH#P05741 MONDO|Ensembl=ENSMODG00000020680.4|UniProtKB=F7DL69 F7DL69 PDCL2 PTHR45809:SF1 VIRAL IAP-ASSOCIATED FACTOR HOMOLOG PHOSDUCIN-LIKE PROTEIN 2 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000021098.4|UniProtKB=F6UID4 F6UID4 USP9X PTHR24006:SF925 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITINYL HYDROLASE 1 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cell migration#GO:0016477;cell motility#GO:0048870;cellular process#GO:0009987;regulation of protein stability#GO:0031647 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000018586.4|UniProtKB=F7FD35 F7FD35 LMBRD1 PTHR16130:SF3 LYSOSOMAL COBALAMIN TRANSPORTER-RELATED LYSOSOMAL COBALAMIN TRANSPORT ESCORT PROTEIN LMBD1 protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to vacuole#GO:0072665;protein localization to lysosome#GO:0061462 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;lysosomal membrane#GO:0005765;cytoplasm#GO:0005737;vacuole#GO:0005773 transporter#PC00227 MONDO|Ensembl=ENSMODG00000017859.5|UniProtKB=F6YIK3 F6YIK3 PDE3A PTHR11347:SF104 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;cyclic-nucleotide phosphodiesterase activity#GO:0004112 regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphodiesterase#PC00185;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000010605.3|UniProtKB=F7G895 F7G895 PTHR21650:SF4 MEMBRALIN/KINETOCHORE PROTEIN NUF2 MEMBRALIN positive regulation of response to stimulus#GO:0048584;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of ERAD pathway#GO:1904292;positive regulation of proteasomal protein catabolic process#GO:1901800;cellular response to stimulus#GO:0051716;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;regulation of cellular response to stress#GO:0080135;response to endoplasmic reticulum stress#GO:0034976;positive regulation of protein metabolic process#GO:0051247;cellular response to stress#GO:0033554 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000003215.4|UniProtKB=A0A5F8GJE4 A0A5F8GJE4 TANGO6 PTHR20959:SF1 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 FAMILY MEMBER TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 HOMOLOG transport#GO:0006810;protein transport#GO:0015031;establishment of protein localization to extracellular region#GO:0035592;secretion by cell#GO:0032940;intracellular protein localization#GO:0008104;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;protein secretion#GO:0009306;protein localization to extracellular region#GO:0071692;cellular process#GO:0009987;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;export from cell#GO:0140352 MONDO|Ensembl=ENSMODG00000045839.1|UniProtKB=A0A5F8H9D8 A0A5F8H9D8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000046410.1|UniProtKB=A0A5F8GW64 A0A5F8GW64 PTHR10489:SF689 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 2 cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515 neutrophil chemotaxis#GO:0030593;taxis#GO:0042330;neutrophil migration#GO:1990266;response to chemical#GO:0042221;granulocyte migration#GO:0097530;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of biological quality#GO:0065008;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;leukocyte chemotaxis#GO:0030595;leukocyte migration#GO:0050900;cell migration#GO:0016477;biological regulation#GO:0065007;immune response#GO:0006955;cell communication#GO:0007154;cell chemotaxis#GO:0060326;intracellular signal transduction#GO:0035556;chemotaxis#GO:0006935;regulation of cellular process#GO:0050794;cell motility#GO:0048870;locomotion#GO:0040011;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 cell adhesion molecule#PC00069 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000018886.2|UniProtKB=F7CR88 F7CR88 PLA2G7 PTHR10272:SF12 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000013039.5|UniProtKB=F7GBL6 F7GBL6 MSL1 PTHR21656:SF2 MALE-SPECIFIC LETHAL-1 PROTEIN MALE-SPECIFIC LETHAL 1 HOMOLOG chromatin binding#GO:0003682;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000022929.1|UniProtKB=F7A114 F7A114 LOC100020685 PTHR26450:SF117 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007432.3|UniProtKB=F7EDP2 F7EDP2 PTHR12510:SF4 TROPONIN C-AKIN-1 PROTEIN GAMMA-GLUTAMYLAMINECYCLOTRANSFERASE cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000005447.3|UniProtKB=F7CH07 F7CH07 DCSTAMP PTHR21041:SF2 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN developmental process#GO:0032502;cellular developmental process#GO:0048869;single fertilization#GO:0007338;cellular process#GO:0009987;hemopoiesis#GO:0030097;cell-cell fusion#GO:0140253;sexual reproduction#GO:0019953;syncytium formation by cell-cell fusion#GO:0000768;anatomical structure development#GO:0048856;osteoclast differentiation#GO:0030316;leukocyte differentiation#GO:0002521;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;reproductive process#GO:0022414;cell development#GO:0048468;fertilization#GO:0009566 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;cell surface#GO:0009986;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000006294.4|UniProtKB=F7CAC4 F7CAC4 PTHR45623:SF6 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD5 catalytic activity, acting on a nucleic acid#GO:0140640;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;histone binding#GO:0042393;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;hydrolase activity#GO:0016787;DNA binding#GO:0003677;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000047927.1|UniProtKB=A0A5F8HH53 A0A5F8HH53 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008733.6|UniProtKB=F7FKE8 F7FKE8 KRT76 PTHR45616:SF38 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 3 structural molecule activity#GO:0005198 organelle organization#GO:0006996;cellular process#GO:0009987;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epidermis development#GO:0008544;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;animal organ development#GO:0048513;cellular component organization#GO:0016043;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;intermediate filament-based process#GO:0045103;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000028809.2|UniProtKB=K7DZ94 K7DZ94 PTHR23226:SF430 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 1010-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008485.4|UniProtKB=A0A5F8GPW8 A0A5F8GPW8 PTHR10751:SF32 GUANYLATE BINDING PROTEIN ATLASTIN-3 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 organelle organization#GO:0006996;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 heterotrimeric G-protein#PC00117;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000013714.3|UniProtKB=F6Y9C6 F6Y9C6 PTHR12186:SF3 SIKE FAMILY MEMBER FGFR1 ONCOGENE PARTNER 2 response to stimulus#GO:0050896;response to stress#GO:0006950;response to wounding#GO:0009611 MONDO|Ensembl=ENSMODG00000012201.4|UniProtKB=F7CE89 F7CE89 AIFM2 PTHR43735:SF27 APOPTOSIS-INDUCING FACTOR 1 FERROPTOSIS SUPPRESSOR PROTEIN 1 catalytic activity#GO:0003824;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;binding#GO:0005488;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;electron transfer activity#GO:0009055 regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;organelle organization#GO:0006996;apoptotic mitochondrial changes#GO:0008637;biological regulation#GO:0065007;mitochondrion organization#GO:0007005;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;programmed cell death#GO:0012501;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 p53 pathway#P00059>NOXA#G01572 MONDO|Ensembl=ENSMODG00000001811.4|UniProtKB=F6T5S0 F6T5S0 SQLE PTHR10835:SF0 SQUALENE MONOOXYGENASE SQUALENE MONOOXYGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxygenase#PC00177 Cholesterol biosynthesis#P00014>Squalene monooxygenas#P00494 MONDO|Ensembl=ENSMODG00000050854.1|UniProtKB=A0A5F8GF86 A0A5F8GF86 CYP4V2 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000012703.5|UniProtKB=F6UY85 F6UY85 PTHR12207:SF27 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2B cellular anatomical structure#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000001412.3|UniProtKB=F6YYE6 F6YYE6 TWIST2 PTHR23349:SF70 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TWIST-RELATED PROTEIN 2 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000010634.3|UniProtKB=F7D539 F7D539 HDAC3 PTHR10625:SF36 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 3 catalytic activity#GO:0003824;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096;histone modifying activity#GO:0140993 epigenetic regulation of gene expression#GO:0040029;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513 Wnt signaling pathway#P00057>Histone deacetylase#P01472 MONDO|Ensembl=ENSMODG00000015219.4|UniProtKB=A0A5F8GBT6 A0A5F8GBT6 PTHR21665:SF2 CATION CHANNEL SPERM-ASSOCIATED TARGETING SUBUNIT TAU CATION CHANNEL SPERM-ASSOCIATED TARGETING SUBUNIT TAU MONDO|Ensembl=ENSMODG00000047150.1|UniProtKB=A0A5F8G8L6 A0A5F8G8L6 LOC100013123 PTHR26453:SF729 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011028.4|UniProtKB=F7F4D5 F7F4D5 DCC PTHR10075:SF115 BASIGIN RELATED NETRIN RECEPTOR DCC cell adhesion molecule#PC00069 Axon guidance mediated by Slit/Robo#P00008>DCC#P00352;Axon guidance mediated by netrin#P00009>DCC/UNC-40#P00360 MONDO|Ensembl=ENSMODG00000043177.1|UniProtKB=A0A5F8H4U3 A0A5F8H4U3 PTHR16674:SF2 B-LYMPHOCYTE ANTIGEN CD19 B-LYMPHOCYTE ANTIGEN CD19 signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;B cell receptor signaling pathway#GO:0050853;cellular process#GO:0009987;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune system process#GO:0002376;regulation of immune response#GO:0050776;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 B cell activation#P00010>CD19#P00393 MONDO|Ensembl=ENSMODG00000021017.3|UniProtKB=F6QZD4 F6QZD4 TFF3 PTHR13826:SF16 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 3 multicellular organismal-level homeostasis#GO:0048871;system process#GO:0003008;tissue homeostasis#GO:0001894;homeostatic process#GO:0042592;epithelial structure maintenance#GO:0010669;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;digestion#GO:0007586 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000005745.4|UniProtKB=F6QE74 F6QE74 KEAP1 PTHR24412:SF162 KELCH PROTEIN KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006211.3|UniProtKB=F6ZSN4 F6ZSN4 LOC100616964 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019421.2|UniProtKB=F6SYE5 F6SYE5 AK6 PTHR12595:SF0 POS9-ACTIVATING FACTOR FAP7-RELATED ADENYLATE KINASE ISOENZYME 6 nucleobase-containing compound kinase activity#GO:0019205;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;phosphotransferase activity, phosphate group as acceptor#GO:0016776;kinase activity#GO:0016301;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;transferase activity#GO:0016740;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;nucleotide binding#GO:0000166 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000042817.1|UniProtKB=A0A5F8HFQ2 A0A5F8HFQ2 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000044303.1|UniProtKB=A0A5F8G7T3 A0A5F8G7T3 PTHR11213:SF6 GLUCAGON-FAMILY NEUROPEPTIDE SOMATOLIBERIN receptor ligand activity#GO:0048018;neuropeptide receptor binding#GO:0071855;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;neuropeptide hormone activity#GO:0005184;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179 establishment of localization#GO:0051234;regulation of response to stimulus#GO:0048583;transport#GO:0006810;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;positive regulation of cellular process#GO:0048522;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;peptide hormone secretion#GO:0030072;signal release#GO:0023061;peptide secretion#GO:0002790;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of localization#GO:0032879;hormone transport#GO:0009914;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;hormone secretion#GO:0046879;regulation of biological quality#GO:0065008;secretion by cell#GO:0032940;regulation of protein localization#GO:0032880;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;signaling#GO:0023052;export from cell#GO:0140352;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789 axon#GO:0030424;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron projection terminus#GO:0044306;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;terminal bouton#GO:0043195;cell body#GO:0044297;cell junction#GO:0030054;perikaryon#GO:0043204;axon terminus#GO:0043679;somatodendritic compartment#GO:0036477;presynapse#GO:0098793;neuron projection#GO:0043005 neuropeptide#PC00162 MONDO|Ensembl=ENSMODG00000038708.1|UniProtKB=A0A5F8H485 A0A5F8H485 PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN protein binding#GO:0005515;peptide binding#GO:0042277;antigen binding#GO:0003823;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;regulation of leukocyte mediated cytotoxicity#GO:0001910;antigen processing and presentation#GO:0019882;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of leukocyte mediated immunity#GO:0002705 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000028924.2|UniProtKB=K7E408 K7E408 PTHR24366:SF134 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS CHONDROADHERIN-LIKE PROTEIN immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000022965.3|UniProtKB=F6UYX5 F6UYX5 SEC22C PTHR46258:SF2 LONGIN DOMAIN-CONTAINING PROTEIN VESICLE-TRAFFICKING PROTEIN SEC22C vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 MONDO|Ensembl=ENSMODG00000005331.4|UniProtKB=A0A5F8H3E9 A0A5F8H3E9 OPCML PTHR42757:SF17 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED OPIOID-BINDING PROTEIN_CELL ADHESION MOLECULE biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of synapse assembly#GO:0051963;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell-cell adhesion#GO:0098609;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803;cell adhesion#GO:0007155;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807 cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;organelle#GO:0043226;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;plasma membrane#GO:0005886;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;postsynaptic density#GO:0014069 immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000014860.4|UniProtKB=F7BYK6 F7BYK6 CNTLN PTHR18957:SF0 CENTLEIN CENTLEIN cellular process#GO:0009987;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000014378.4|UniProtKB=F6T7T7 F6T7T7 MYT1L PTHR10816:SF11 MYELIN TRANSCRIPTION FACTOR 1-RELATED MYELIN TRANSCRIPTION FACTOR 1-LIKE PROTEIN transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000007892.3|UniProtKB=F6ZG99 F6ZG99 TOMM20L PTHR12430:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 TOMM20-LIKE PROTEIN 1 intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;transmembrane transport#GO:0055085;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;protein localization to mitochondrion#GO:0070585;establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;nucleobase-containing compound transport#GO:0015931;mitochondrial transport#GO:0006839 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane translocase complex#GO:0005742;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000013654.4|UniProtKB=F6UD58 F6UD58 SSC4D PTHR19331:SF439 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING GROUP B PROTEIN cargo receptor activity#GO:0038024 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000025413.3|UniProtKB=F6QFT6 F6QFT6 KCNJ15 PTHR11767:SF20 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 15 voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857 monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;cellular process#GO:0009987;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;transport#GO:0006810;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000015155.4|UniProtKB=F7CFN3 F7CFN3 TGFBR2 PTHR23255:SF55 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II TGF-BETA RECEPTOR TYPE-2 catalytic activity, acting on a protein#GO:0140096;cytokine binding#GO:0019955;transmembrane receptor protein kinase activity#GO:0019199;transforming growth factor beta binding#GO:0050431;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;signaling receptor binding#GO:0005102;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;activin binding#GO:0048185;transforming growth factor beta receptor activity#GO:0005024;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;cytokine receptor binding#GO:0005126;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;transmembrane signaling receptor activity#GO:0004888 nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;cellular process#GO:0009987;signal transduction#GO:0007165;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;activin receptor signaling pathway#GO:0032924;animal gross anatomical part developmental process#GO:0160108 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283 MONDO|Ensembl=ENSMODG00000025206.2|UniProtKB=F7BFQ5 F7BFQ5 PTHR10476:SF18 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 1B cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;late endosome to vacuole transport#GO:0045324;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;late endosome#GO:0005770;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000001526.4|UniProtKB=A0A5F8H3I2 A0A5F8H3I2 LOC100014897 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020339.3|UniProtKB=F7FWL8 F7FWL8 TMEM109 PTHR14550:SF2 TRANSMEMBRANE PROTEIN 109 VOLTAGE-GATED MONOATOMIC CATION CHANNEL TMEM109 biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;response to radiation#GO:0009314;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;apoptotic signaling pathway#GO:0097190;cellular response to abiotic stimulus#GO:0071214;DNA damage response#GO:0006974;cellular response to radiation#GO:0071478;signaling#GO:0023052;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to ionizing radiation#GO:0010212;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;signal transduction by p53 class mediator#GO:0072331 MONDO|Ensembl=ENSMODG00000012104.4|UniProtKB=F7FUE8 F7FUE8 DLX4 PTHR24327:SF21 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;embryo development#GO:0009790;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;embryo development ending in birth or egg hatching#GO:0009792 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000003352.4|UniProtKB=A0A5F8GNI1 A0A5F8GNI1 GGNBP2 PTHR13601:SF4 GAMETOGENETIN-BINDING PROTEIN 2 GAMETOGENETIN-BINDING PROTEIN 2 cellular developmental process#GO:0048869;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000014482.3|UniProtKB=F6ZG19 F6ZG19 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000025618.3|UniProtKB=F6QB63 F6QB63 PTHR16866:SF2 GASTRIN-RELEASING PEPTIDE GASTRIN-RELEASING PEPTIDE regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;regulation of defense response#GO:0031347;regulation of response to stimulus#GO:0048583;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239 MONDO|Ensembl=ENSMODG00000002220.4|UniProtKB=F7DG08 F7DG08 USP8 PTHR21646:SF27 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 8 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of signaling#GO:0023051;regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;response to stimulus#GO:0050896;endosome organization#GO:0007032;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of protein stability#GO:0031647;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of canonical Wnt signaling pathway#GO:0060828;organelle organization#GO:0006996;intracellular signaling cassette#GO:0141124;endomembrane system organization#GO:0010256;positive regulation of Wnt signaling pathway#GO:0030177;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584 intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;postsynaptic density#GO:0014069;cytoplasm#GO:0005737;organelle#GO:0043226;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;postsynapse#GO:0098794;midbody#GO:0030496 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000027820.2|UniProtKB=K7E1Z1 K7E1Z1 EIF1AX PTHR21668:SF6 EIF-1A EUKARYOTIC TRANSLATION INITIATION FACTOR 1A, X-CHROMOSOMAL translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000018853.5|UniProtKB=A0A5F8H831 A0A5F8H831 PTHR10686:SF12 FOLATE TRANSPORTER REDUCED FOLATE TRANSPORTER carboxylic acid binding#GO:0031406;binding#GO:0005488;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;organic acid binding#GO:0043177;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;dicarboxylic acid transmembrane transporter activity#GO:0005310;active transmembrane transporter activity#GO:0022804 vitamin transport#GO:0051180;dicarboxylic acid transport#GO:0006835;carboxylic acid transmembrane transport#GO:1905039;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;apical plasma membrane#GO:0016324;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177 transporter#PC00227 MONDO|Ensembl=ENSMODG00000021346.4|UniProtKB=H9H7Y7 H9H7Y7 OS9 PTHR15414:SF5 OS-9-RELATED PROTEIN OS-9 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to unfolded protein#GO:0006986;cellular localization#GO:0051641;regulation of biological process#GO:0050789;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;intracellular protein localization#GO:0008104;macromolecule metabolic process#GO:0043170;macromolecule localization#GO:0033036;endoplasmic reticulum unfolded protein response#GO:0030968;biological regulation#GO:0065007;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;localization#GO:0051179;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788 MONDO|Ensembl=ENSMODG00000016144.4|UniProtKB=F7D7F0 F7D7F0 HNRNPR PTHR21245:SF5 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN R RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000019476.3|UniProtKB=F6WAD9 F6WAD9 PTHR19321:SF1 PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED PROTEIN REGULATOR OF CYTOKINESIS 1 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;microtubule cytoskeleton organization involved in mitosis#GO:1902850;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;organelle assembly#GO:0070925;nuclear division#GO:0000280;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000004343.4|UniProtKB=F6X5V3 F6X5V3 GPD2 PTHR11985:SF15 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000003552.4|UniProtKB=F7GBE2 F7GBE2 MYO10 PTHR46049:SF2 AGAP003327-PA UNCONVENTIONAL MYOSIN-X isomerase activity#GO:0016853;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;phospholipid binding#GO:0005543;macromolecular conformation isomerase activity#GO:0120543;ion binding#GO:0043167;polypeptide conformation or assembly isomerase activity#GO:0120544;anion binding#GO:0043168;small molecule binding#GO:0036094;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;ATP-dependent activity#GO:0140657 regulation of cell projection organization#GO:0031344;intracellular transport#GO:0046907;transport#GO:0006810;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;establishment of localization#GO:0051234;regulation of filopodium assembly#GO:0051489;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;localization#GO:0051179;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;regulation of cell projection assembly#GO:0060491;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;filopodium#GO:0030175 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000051346.1|UniProtKB=A0A5F8HFN1 A0A5F8HFN1 PTHR13026:SF1 NNP-1 PROTEIN NOVEL NUCLEAR PROTEIN 1 NOP52 RIBOSOMAL RNA PROCESSING PROTEIN 1 HOMOLOG A transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000004706.4|UniProtKB=F6QH65 F6QH65 CRISPLD2 PTHR10334:SF64 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN LCCL DOMAIN-CONTAINING 2 binding#GO:0005488;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367 anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;head development#GO:0060322;anatomical structure development#GO:0048856 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000010039.4|UniProtKB=F7B6F0 F7B6F0 CFAP45 PTHR15504:SF1 NASOPHARYNGEAL EPITHELIUM SPECIFIC PROTEIN 1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 45 sperm motility#GO:0097722;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;cell motility#GO:0048870;regulation of microtubule-based movement#GO:0060632;reproductive process#GO:0022414;regulation of microtubule-based process#GO:0032886;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;regulation of cell motility#GO:2000145;cilium-dependent cell motility#GO:0060285;regulation of biological quality#GO:0065008;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;flagellated sperm motility#GO:0030317;microtubule-based process#GO:0007017 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;cytoplasmic microtubule#GO:0005881;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ciliary plasm#GO:0097014;sperm flagellum#GO:0036126;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000021348.3|UniProtKB=H9H7Z0 H9H7Z0 CYP27B1 PTHR24291:SF3 CYTOCHROME P450 FAMILY 4 25-HYDROXYVITAMIN D-1 ALPHA HYDROXYLASE, MITOCHONDRIAL monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 response to oxygen-containing compound#GO:1901700;steroid catabolic process#GO:0006706;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;vitamin D metabolic process#GO:0042359;steroid biosynthetic process#GO:0006694;alcohol biosynthetic process#GO:0046165;lipid catabolic process#GO:0016042;cellular process#GO:0009987;response to nutrient levels#GO:0031667;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;response to chemical#GO:0042221;response to lipid#GO:0033993;lipid biosynthetic process#GO:0008610 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>1alpha-Hydroxylase#P04603;Vitamin D metabolism and pathway#P04396>25-Hydroxylase#P04601 MONDO|Ensembl=ENSMODG00000001359.4|UniProtKB=F7FJA3 F7FJA3 PTHR47966:SF24 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED RENIN aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;circulatory system process#GO:0003013;proteolysis#GO:0006508;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of biological quality#GO:0065008;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;peptide hormone processing#GO:0016486;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;gene expression#GO:0010467;blood circulation#GO:0008015;hormone metabolic process#GO:0042445;biosynthetic process#GO:0009058;biological regulation#GO:0065007;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;system process#GO:0003008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 aspartic protease#PC00053;protease#PC00190 MONDO|Ensembl=ENSMODG00000000973.3|UniProtKB=F7ESU5 F7ESU5 CRIPT PTHR11805:SF2 CYSTEINE-RICH PDZ-BINDING PROTEIN CYSTEINE-RICH PDZ-BINDING PROTEIN microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122;cytoskeleton organization#GO:0007010 plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;neuron projection#GO:0043005;dendrite#GO:0030425 MONDO|Ensembl=ENSMODG00000013415.5|UniProtKB=F7CNI7 F7CNI7 PRDM6 PTHR16515:SF22 PR DOMAIN ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE PRDM6-RELATED regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000011164.3|UniProtKB=F6ZZV4 F6ZZV4 LOC100021201 PTHR26450:SF393 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR FAMILY 51 SUBFAMILY AC MEMBER 9, PSEUDO signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000043457.1|UniProtKB=A0A5F8GJ34 A0A5F8GJ34 HCCS PTHR12743:SF0 CYTOCHROME C1 HEME LYASE HOLOCYTOCHROME C-TYPE SYNTHASE catalytic activity#GO:0003824;carbon-sulfur lyase activity#GO:0016846;catalytic activity, acting on a protein#GO:0140096;lyase activity#GO:0016829 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 lyase#PC00144 MONDO|Ensembl=ENSMODG00000045266.1|UniProtKB=A0A5F8GWE0 A0A5F8GWE0 PTHR23262:SF50 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-8 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000011152.2|UniProtKB=F7ANM5 F7ANM5 PTHR26450:SF29 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR FAMILY 51 SUBFAMILY AF MEMBER 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010024.4|UniProtKB=F6U9U7 F6U9U7 IGSF9 PTHR10075:SF139 BASIGIN RELATED PROTEIN TURTLE HOMOLOG A cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000020485.4|UniProtKB=F7F5G2 F7F5G2 METTL25 PTHR12496:SF9 CGI-41 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 25-RELATED RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000012555.4|UniProtKB=A0A5F8GZ27 A0A5F8GZ27 DDX31 PTHR24031:SF89 RNA HELICASE ATP-DEPENDENT DNA HELICASE DDX31 cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000042671.1|UniProtKB=A0A5F8GIM9 A0A5F8GIM9 IQCJ PTHR35976:SF1 IQ DOMAIN-CONTAINING PROTEIN J IQ DOMAIN-CONTAINING PROTEIN J MONDO|Ensembl=ENSMODG00000043822.1|UniProtKB=A0A5F8GN30 A0A5F8GN30 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000015190.4|UniProtKB=F7BW00 F7BW00 MEOX1 PTHR24328:SF8 HOMEOBOX PROTEIN MOX HOMEOBOX PROTEIN MOX-1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;embryo development#GO:0009790;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000011438.4|UniProtKB=F6RJN0 F6RJN0 MFSD1 PTHR23512:SF13 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 LYSOSOMAL DIPEPTIDE TRANSPORTER MFSD1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764 MONDO|Ensembl=ENSMODG00000023068.2|UniProtKB=F7GBX1 F7GBX1 LOC103093381 PTHR16675:SF67 MHC CLASS I-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000000420.5|UniProtKB=F6VAR6 F6VAR6 C1QL2 PTHR22923:SF69 CEREBELLIN-RELATED COMPLEMENT C1Q-LIKE PROTEIN 2 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017096.4|UniProtKB=K7E5N6 K7E5N6 ZNF362 PTHR24393:SF151 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 956 transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011373.2|UniProtKB=F6SPP7 F6SPP7 LOC100022548 PTHR26450:SF72 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000039354.1|UniProtKB=A0A5F8H995 A0A5F8H995 LOC100619160 PTHR26454:SF165 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6T1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008566.4|UniProtKB=A0A5F8HFF2 A0A5F8HFF2 MBNL2 PTHR12675:SF4 MUSCLEBLIND-LIKE PROTEIN MUSCLEBLIND-LIKE PROTEIN 2 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000009394.3|UniProtKB=A0A5F8G7M2 A0A5F8G7M2 PDZD8 PTHR21519:SF1 PDZ DOMAIN-CONTAINING PROTEIN 8 PDZ DOMAIN-CONTAINING PROTEIN 8 mitochondrial calcium ion homeostasis#GO:0051560;homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080 organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondria-associated endoplasmic reticulum membrane contact site#GO:0044233;organelle membrane contact site#GO:0044232 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018136.4|UniProtKB=A0A5F8HFG9 A0A5F8HFG9 PTHR11890:SF18 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER LYMPHOCYTE ACTIVATION GENE 3 PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015939.2|UniProtKB=F6Z365 F6Z365 CRYGA PTHR11818:SF145 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN D structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600;visual perception#GO:0007601;visual system development#GO:0150063;sensory perception of light stimulus#GO:0050953;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;multicellular organismal process#GO:0032501;sensory system development#GO:0048880 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000023380.3|UniProtKB=F6TR60 F6TR60 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000027336.2|UniProtKB=K7E4J9 K7E4J9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000028680.2|UniProtKB=K7E3E3 K7E3E3 LOC103098148 PTHR38654:SF1 BUCKY BALL-RELATED BUCKY BALL MONDO|Ensembl=ENSMODG00000007870.4|UniProtKB=A0A5F8HGK0 A0A5F8HGK0 PDE2A PTHR11347:SF102 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC PHOSPHODIESTERASE PDE-2-RELATED phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;identical protein binding#GO:0042802;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;protein binding#GO:0005515;binding#GO:0005488 purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cyclic purine nucleotide metabolic process#GO:0052652;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968;regulation of intracellular signal transduction#GO:1902531;ribonucleotide metabolic process#GO:0009259;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;nucleotide metabolic process#GO:0009117;negative regulation of cell communication#GO:0010648;phosphorus metabolic process#GO:0006793;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;small molecule metabolic process#GO:0044281;regulation of cellular component organization#GO:0051128;nucleotide catabolic process#GO:0009166;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;cyclic nucleotide metabolic process#GO:0009187;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;positive regulation of cellular process#GO:0048522;ribonucleotide catabolic process#GO:0009261;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of signal transduction#GO:0009966;purine nucleotide catabolic process#GO:0006195;positive regulation of biosynthetic process#GO:0009891;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;purine ribonucleotide catabolic process#GO:0009154;regulation of mitochondrion organization#GO:0010821;nucleoside phosphate catabolic process#GO:1901292;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;regulation of cell communication#GO:0010646 perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;organelle inner membrane#GO:0019866;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;synaptic membrane#GO:0097060;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;outer membrane#GO:0019867;intracellular organelle lumen#GO:0070013;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;cell periphery#GO:0071944;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;cytosol#GO:0005829;mitochondrial inner membrane#GO:0005743;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000037101.1|UniProtKB=H9H694 H9H694 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000017753.4|UniProtKB=F7E523 F7E523 HSF2 PTHR10015:SF185 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000006942.4|UniProtKB=F6RGD5 F6RGD5 FDXR PTHR11938:SF151 FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE NADPH:ADRENODOXIN OXIDOREDUCTASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid biosynthetic process#GO:0008610;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FdxR#P04604 MONDO|Ensembl=ENSMODG00000019271.3|UniProtKB=F6SI25 F6SI25 LOC100014953 PTHR22792:SF166 LUPUS LA PROTEIN-RELATED LUPUS LA PROTEIN HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000024504.3|UniProtKB=F7B7Y2 F7B7Y2 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010219.3|UniProtKB=F6RRY1 F6RRY1 DCAF5 PTHR15574:SF43 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 5 negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of lipid biosynthetic process#GO:0046890;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of biological process#GO:0048519;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of lipid metabolic process#GO:0019216 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000011958.4|UniProtKB=F7CV05 F7CV05 LOC100023534 PTHR45973:SF2 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED CENTROSOMAL PROTEIN OF 97 KDA regulation of cell projection assembly#GO:0060491;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344;regulation of cilium assembly#GO:1902017;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000016136.3|UniProtKB=F7DRU9 F7DRU9 LOC100022960 PTHR26453:SF52 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017533.3|UniProtKB=F7EHW4 F7EHW4 TAAR5 PTHR24249:SF307 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 5 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000001212.4|UniProtKB=F7G7S6 F7G7S6 RET PTHR24416:SF485 TYROSINE-PROTEIN KINASE RECEPTOR PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000029792.2|UniProtKB=K7E3G0 K7E3G0 PTHR22810:SF1 TESTIS DEVELOPMENT PROTEIN NYD-SP26 CALCIUM-BINDING AND SPERMATID-SPECIFIC PROTEIN 1 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;sperm motility#GO:0097722;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017 intracellular vesicle#GO:0097708;sperm principal piece#GO:0097228;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;acrosomal vesicle#GO:0001669;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;sperm flagellum#GO:0036126;endomembrane system#GO:0012505;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000005947.4|UniProtKB=F6WG08 F6WG08 PHF13 PTHR14571:SF13 HISTONE-LYSINE N-METHYLTRANSFERASE SET-26-RELATED PHD FINGER PROTEIN 13 chromatin binding#GO:0003682;binding#GO:0005488 chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;organelle fission#GO:0048285;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cell cycle#GO:0007049;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000004569.4|UniProtKB=F6R4S4 F6R4S4 MOB3A PTHR22599:SF10 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 3A kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000047142.1|UniProtKB=A0A5F8HKC1 A0A5F8HKC1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003325.4|UniProtKB=A0A5F8HI21 A0A5F8HI21 LOC100027703 PTHR43655:SF7 ATP-DEPENDENT PROTEASE MITOCHONDRIAL INNER MEMBRANE M-AAA PROTEASE COMPONENT AFG3L1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059 membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;peptidase complex#GO:1905368;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000017144.4|UniProtKB=A0A5F8GY03 A0A5F8GY03 SCML2 PTHR12247:SF84 POLYCOMB GROUP PROTEIN SEX COMB ON MIDLEG-LIKE PROTEIN 2 protein binding#GO:0005515;histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000020429.4|UniProtKB=F7ARM2 F7ARM2 RAX PTHR46271:SF3 HOMEOBOX PROTEIN, PUTATIVE-RELATED RETINAL HOMEOBOX PROTEIN RX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000023933.2|UniProtKB=F7F897 F7F897 RNF186 PTHR22791:SF28 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF186 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000003327.4|UniProtKB=F7DDI2 F7DDI2 ORC4 PTHR12087:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;protein-macromolecule adaptor activity#GO:0030674;nucleic acid binding#GO:0003676;DNA replication origin binding#GO:0003688;binding#GO:0005488;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170 chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nuclear origin of replication recognition complex#GO:0005664;origin recognition complex#GO:0000808;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 MONDO|Ensembl=ENSMODG00000028496.2|UniProtKB=M9MMH8 M9MMH8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000002341.4|UniProtKB=A0A5F8GTA3 A0A5F8GTA3 ATPSCKMT PTHR13610:SF8 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN ATP SYNTHASE SUBUNIT C LYSINE N-METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of system process#GO:0044057;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000006061.4|UniProtKB=F7FF88 F7FF88 EIF2B2 PTHR45859:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA TRANSLATION INITIATION FACTOR EIF2B SUBUNIT BETA translation factor activity#GO:0180051;guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412 cellular anatomical structure#GO:0110165;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000037714.1|UniProtKB=A0A5F8GZE1 A0A5F8GZE1 CIR1 PTHR13151:SF2 CBF1 INTERACTING COREPRESSOR CIR COREPRESSOR OF RBPJ AND SPLICING REGULATOR transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 Notch signaling pathway#P00045>CoR#P01112 MONDO|Ensembl=ENSMODG00000038707.1|UniProtKB=A0A5F8GFH2 A0A5F8GFH2 DSG4 PTHR24025:SF10 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-4 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell-cell junction#GO:0005911 cadherin#PC00057 MONDO|Ensembl=ENSMODG00000016968.3|UniProtKB=F6V4R7 F6V4R7 EGR4 PTHR23235:SF58 KRUEPPEL-LIKE TRANSCRIPTION FACTOR EARLY GROWTH RESPONSE PROTEIN 4 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000003744.4|UniProtKB=A0A5F8HKN2 A0A5F8HKN2 PTHR12509:SF8 SPERMATOGENESIS-ASSOCIATED 4-RELATED SPERMATOGENESIS-ASSOCIATED PROTEIN 4 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789 plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;axoneme#GO:0005930;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000002234.4|UniProtKB=F7DFT7 F7DFT7 HSP90B1 PTHR11528:SF144 HEAT SHOCK PROTEIN 90 FAMILY MEMBER ENDOPLASMIN ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367 protein folding#GO:0006457;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Hsp90 family chaperone#PC00028;chaperone#PC00072 MONDO|Ensembl=ENSMODG00000017773.4|UniProtKB=F7DJF8 F7DJF8 GNL2 PTHR11089:SF9 GTP-BINDING PROTEIN-RELATED NUCLEOLAR GTP-BINDING PROTEIN 2 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000006166.4|UniProtKB=F7B5L7 F7B5L7 COQ7 PTHR11237:SF6 COENZYME Q10 BIOSYNTHESIS PROTEIN 7 NADPH-DEPENDENT 3-DEMETHOXYUBIQUINONE 3-HYDROXYLASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 ketone metabolic process#GO:0042180;regulation of metabolic process#GO:0019222;ubiquinone biosynthetic process#GO:0006744;regulation of biological process#GO:0050789;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;small molecule metabolic process#GO:0044281;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;regulation of reactive oxygen species metabolic process#GO:2000377;small molecule biosynthetic process#GO:0044283 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000015119.4|UniProtKB=F7ELX9 F7ELX9 MB21D2 PTHR10656:SF47 CELL FATE DETERMINING PROTEIN MAB21-RELATED NUCLEOTIDYLTRANSFERASE MB21D2 nucleotidyltransferase#PC00174;transferase#PC00220 MONDO|Ensembl=ENSMODG00000038017.1|UniProtKB=A0A5F8GFK1 A0A5F8GFK1 LDLRAD1 PTHR22722:SF20 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000014670.2|UniProtKB=F7E803 F7E803 RAB39A PTHR47979:SF3 DRAB11-RELATED RAS-RELATED PROTEIN RAB-39A heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 membrane fusion#GO:0061025;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;lysosome organization#GO:0007040;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;phagocytosis#GO:0006909;phagolysosome assembly#GO:0001845;transport#GO:0006810;lytic vacuole organization#GO:0080171;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;cellular component organization#GO:0016043;endocytosis#GO:0006897;vesicle fusion#GO:0006906;organelle assembly#GO:0070925;localization#GO:0051179;vacuole organization#GO:0007033 G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000015152.3|UniProtKB=F7CFQ6 F7CFQ6 SMAD5 PTHR13703:SF36 SMAD SMAD FAMILY MEMBER 5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of macromolecule metabolic process#GO:0060255;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;BMP signaling pathway#GO:0030509;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;response to transforming growth factor beta#GO:0071559 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD1/5/8#P06787;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292;Wnt signaling pathway#P00057>Smad4#P01455 MONDO|Ensembl=ENSMODG00000011805.3|UniProtKB=F7CBJ3 F7CBJ3 NFU1 PTHR11178:SF1 IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000003456.5|UniProtKB=A0A5F8G7I3 A0A5F8G7I3 ITGB2 PTHR10082:SF15 INTEGRIN BETA SUBUNIT INTEGRIN BETA-2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;peptide binding#GO:0042277;integrin binding#GO:0005178;cell adhesion molecule binding#GO:0050839 regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;leukocyte cell-cell adhesion#GO:0007159;signal transduction#GO:0007165;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;neutrophil migration#GO:1990266;taxis#GO:0042330;response to chemical#GO:0042221;granulocyte migration#GO:0097530;cell surface receptor signaling pathway#GO:0007166;neutrophil chemotaxis#GO:0030593;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;cell motility#GO:0048870;regulation of cellular process#GO:0050794;chemotaxis#GO:0006935;cell chemotaxis#GO:0060326;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;biological regulation#GO:0065007;cell migration#GO:0016477;cell adhesion mediated by integrin#GO:0033627;leukocyte migration#GO:0050900;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;leukocyte chemotaxis#GO:0030595 cell junction#GO:0030054;integrin complex#GO:0008305;anchoring junction#GO:0070161;signaling receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944 integrin#PC00126 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853;Integrin signalling pathway#P00034>Integrin beta#P00931 MONDO|Ensembl=ENSMODG00000012108.3|UniProtKB=F7FUD7 F7FUD7 PRDM12 PTHR16515:SF20 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 12 protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000000134.4|UniProtKB=A0A5F8HFK7 A0A5F8HFK7 PPP2R3B PTHR14095:SF1 PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT BETA molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000015843.5|UniProtKB=F6PJ24 F6PJ24 PTHR19229:SF98 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA3 ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876;lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000005141.4|UniProtKB=A0A5F8GV11 A0A5F8GV11 DCTN1 PTHR18916:SF95 DYNACTIN 1-RELATED MICROTUBULE-BINDING DYNACTIN SUBUNIT 1 transport#GO:0006810;intracellular transport#GO:0046907;mitotic cell cycle process#GO:1903047;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle orientation#GO:0000132;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;establishment of spindle localization#GO:0051293;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;cytoskeleton organization#GO:0007010;establishment or maintenance of cell polarity#GO:0007163;organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;spindle localization#GO:0051653;cellular localization#GO:0051641;nuclear migration#GO:0007097;establishment of cell polarity#GO:0030010;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;establishment of organelle localization#GO:0051656 spindle#GO:0005819;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;neuron projection#GO:0043005;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;axon#GO:0030424;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;spindle pole#GO:0000922;chromosome#GO:0005694;kinetochore#GO:0000776;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 chaperone#PC00072 Huntington disease#P00029>Dynactin#P00781 MONDO|Ensembl=ENSMODG00000017765.4|UniProtKB=F7E4K1 F7E4K1 AIRIM PTHR16234:SF5 SIMILAR TO HYPOTHETICAL PROTEIN FLJ20508 AFG2-INTERACTING RIBOSOME MATURATION FACTOR intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000029399.2|UniProtKB=K7E4J8 K7E4J8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003843.4|UniProtKB=F7EBP1 F7EBP1 SH3BP2 PTHR15126:SF4 SH3-BINDING SH3 DOMAIN-BINDING PROTEIN 2 MONDO|Ensembl=ENSMODG00000028361.2|UniProtKB=K7E3L5 K7E3L5 PTHR19422:SF123 GAG RETROVIRAL POLYPROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000005379.4|UniProtKB=F7GGM0 F7GGM0 PTHR45870:SF3 TUBULIN MONOGLYCYLASE TTLL3 PROTEIN MONOGLYCYLASE TTLL8 ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a protein#GO:0140096;ligase activity#GO:0016874;catalytic activity#GO:0003824 developmental process involved in reproduction#GO:0003006;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;microtubule cytoskeleton organization#GO:0000226;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;gamete generation#GO:0007276;cell projection organization#GO:0030030;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;sperm flagellum#GO:0036126;ciliary plasm#GO:0097014;intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514 MONDO|Ensembl=ENSMODG00000023272.1|UniProtKB=F6TDM5 F6TDM5 ABHD16B PTHR12277:SF37 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ABHD16B carboxylic ester hydrolase activity#GO:0052689;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;glycerolipid catabolic process#GO:0046503;organophosphate catabolic process#GO:0046434;cellular process#GO:0009987;lipid catabolic process#GO:0016042;organophosphate metabolic process#GO:0019637;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;acylglycerol catabolic process#GO:0046464;glycerophospholipid catabolic process#GO:0046475;neutral lipid metabolic process#GO:0006638 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000013269.3|UniProtKB=F7D9I2 F7D9I2 RAB33A PTHR47978:SF30 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-33A carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787 metabolic process#GO:0008152;organelle assembly#GO:0070925;autophagosome assembly#GO:0000045;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;catabolic process#GO:0009056 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endosome#GO:0005768 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000023541.2|UniProtKB=F7DDD9 F7DDD9 PTHR46729:SF1 LEUKOCYTE RECEPTOR CLUSTER MEMBER 9 LEUKOCYTE RECEPTOR CLUSTER MEMBER 9 MONDO|Ensembl=ENSMODG00000049927.1|UniProtKB=A0A5F8G5G3 A0A5F8G5G3 MYH1 PTHR45615:SF2 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-1 binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;actin filament binding#GO:0051015;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 muscle system process#GO:0003012;muscle contraction#GO:0006936;system process#GO:0003008;multicellular organismal process#GO:0032501 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867 MONDO|Ensembl=ENSMODG00000002508.3|UniProtKB=A0A5F8GH79 A0A5F8GH79 C8H2orf49 PTHR28359:SF1 ASHWIN TRNA-SPLICING LIGASE COMPLEX SUBUNIT ASW tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000016913.4|UniProtKB=F6VNC9 F6VNC9 TEKT4 PTHR19960:SF12 TEKTIN TEKTIN-4 microtubule-based movement#GO:0007018;cell motility#GO:0048870;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;organelle assembly#GO:0070925;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031 cilium#GO:0005929;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000004290.3|UniProtKB=F6SY37 F6SY37 TMEM129 PTHR31322:SF2 E3 UBIQUITIN-PROTEIN LIGASE TM129 E3 UBIQUITIN-PROTEIN LIGASE TM129 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000001125.4|UniProtKB=F7D533 F7D533 PTHR14096:SF27 APOLIPOPROTEIN L APOLIPOPROTEIN L2 binding#GO:0005488;lipid binding#GO:0008289 membrane#GO:0016020;cellular anatomical structure#GO:0110165 apolipoprotein#PC00052;transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000018489.4|UniProtKB=A0A5F8HHS9 A0A5F8HHS9 MYO6 PTHR13140:SF745 MYOSIN UNCONVENTIONAL MYOSIN-VI isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544 cellular developmental process#GO:0048869;actin filament organization#GO:0007015;neurogenesis#GO:0022008;sensory organ development#GO:0007423;epidermis development#GO:0008544;developmental process#GO:0032502;epithelium development#GO:0060429;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;tissue development#GO:0009888;inner ear development#GO:0048839;actin filament-based movement#GO:0030048;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;system development#GO:0048731;embryonic organ development#GO:0048568;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;animal organ morphogenesis#GO:0009887;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;embryo development#GO:0009790;organelle organization#GO:0006996;inner ear morphogenesis#GO:0042472;hair cell differentiation#GO:0035315;cellular process#GO:0009987;ear development#GO:0043583;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;sensory organ morphogenesis#GO:0090596;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;actin cytoskeleton#GO:0015629;intracellular vesicle#GO:0097708;membraneless organelle#GO:0043228;ruffle#GO:0001726;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000015809.3|UniProtKB=A0A5F8GG55 A0A5F8GG55 HADHB PTHR18919:SF153 ACETYL-COA C-ACYLTRANSFERASE TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;lipid modification#GO:0030258;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282 membrane-enclosed lumen#GO:0031974;oxidoreductase complex#GO:1990204;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex#GO:1990234;organelle lumen#GO:0043233;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;transferase#PC00220 MONDO|Ensembl=ENSMODG00000023801.2|UniProtKB=A0A5F8G6E6 A0A5F8G6E6 PTHR12035:SF125 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 5 binding#GO:0005488;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;anion binding#GO:0043168;carbohydrate derivative binding#GO:0097367;ion binding#GO:0043167;organic acid binding#GO:0043177 cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000017052.5|UniProtKB=K7DZF9 K7DZF9 SOX18 PTHR10270:SF204 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-18 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;tube development#GO:0035295;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;angiogenesis#GO:0001525;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;vasculogenesis#GO:0001570;positive regulation of transcription by RNA polymerase II#GO:0045944;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 MONDO|Ensembl=ENSMODG00000020106.4|UniProtKB=F7EAH4 F7EAH4 SKIC3 PTHR15704:SF7 SUPERKILLER 3 PROTEIN-RELATED SUPERKILLER COMPLEX PROTEIN 3 regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000016153.3|UniProtKB=F7D6K1 F7D6K1 JPT2 PTHR34930:SF5 GEO05313P1 JUPITER MICROTUBULE ASSOCIATED HOMOLOG 2 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000016851.4|UniProtKB=F6QH58 F6QH58 MCM10 PTHR13454:SF11 PROTEIN MCM10 HOMOLOG PROTEIN MCM10 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170 membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000045425.1|UniProtKB=F7FSJ3 F7FSJ3 LOC100029949 PTHR26453:SF69 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000568.4|UniProtKB=A0A5F8GR06 A0A5F8GR06 BUB1B PTHR14030:SF29 MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 MITOTIC CHECKPOINT SERINE_THREONINE-PROTEIN KINASE BUB1 BETA phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 negative regulation of cell cycle phase transition#GO:1901988;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;cellular process#GO:0009987;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;negative regulation of chromosome segregation#GO:0051985;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;regulation of chromosome segregation#GO:0051983;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;meiotic sister chromatid cohesion#GO:0051177;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;negative regulation of chromosome organization#GO:2001251;sister chromatid cohesion#GO:0007062;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic metaphase/anaphase transition#GO:0030071;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;regulation of mitotic sister chromatid separation#GO:0010965;chromosome organization#GO:0051276;regulation of mitotic nuclear division#GO:0007088;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;kinetochore#GO:0000776;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;membraneless organelle#GO:0043228;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000004445.3|UniProtKB=F6RSW7 F6RSW7 NONO PTHR23189:SF15 RNA RECOGNITION MOTIF-CONTAINING NON-POU DOMAIN-CONTAINING OCTAMER-BINDING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000049022.1|UniProtKB=A0A5F8GPM0 A0A5F8GPM0 PTHR24070:SF395 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-1A ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;regulation of exocytosis#GO:0017157;cell communication#GO:0007154;regulation of secretion#GO:0051046;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of transport#GO:0051049;regulation of localization#GO:0032879;intracellular signaling cassette#GO:0141124;response to chemical#GO:0042221;regulation of trans-synaptic signaling#GO:0099177;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;regulation of secretion by cell#GO:1903530;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of neurotransmitter transport#GO:0051588;signaling#GO:0023052;regulation of synaptic vesicle exocytosis#GO:2000300;response to stimulus#GO:0050896;regulation of neurotransmitter secretion#GO:0046928;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;negative regulation of biological process#GO:0048519 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 MONDO|Ensembl=ENSMODG00000002766.4|UniProtKB=F7FBA4 F7FBA4 TERF2 PTHR46833:SF1 TELOMERIC REPEAT-BINDING FACTOR 2 TERF2 TELOMERIC REPEAT-BINDING FACTOR 2 nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleic acid binding#GO:0003676;RNA-directed DNA polymerase activity#GO:0003964;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;transferase activity#GO:0016740;catalytic activity, acting on DNA#GO:0140097;telomerase activity#GO:0003720;DNA polymerase activity#GO:0034061;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;binding#GO:0005488;single-stranded DNA binding#GO:0003697 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;regulation of telomere maintenance via telomere lengthening#GO:1904356;response to stress#GO:0006950;telomere capping#GO:0016233;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of DNA recombination#GO:0000018;cellular response to stress#GO:0033554;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;regulation of telomere maintenance#GO:0032204;telomere maintenance#GO:0000723;intracellular protein localization#GO:0008104;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of chromosome organization#GO:2001251;localization#GO:0051179;telomere organization#GO:0032200;negative regulation of DNA recombination#GO:0045910;primary metabolic process#GO:0044238;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;nuclear telomere cap complex#GO:0000783;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000010792.4|UniProtKB=F7CIB8 F7CIB8 CRTAP PTHR13986:SF3 PROTEIN LYSINE HYDROXYLATION COMPLEX COMPONENT CARTILAGE-ASSOCIATED PROTEIN protein-containing complex binding#GO:0044877;collagen binding#GO:0005518;binding#GO:0005488 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000015258.4|UniProtKB=A0A5F8HGA6 A0A5F8HGA6 TMEM237 PTHR28388:SF1 TRANSMEMBRANE PROTEIN 237 TRANSMEMBRANE PROTEIN 237 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 MONDO|Ensembl=ENSMODG00000011560.4|UniProtKB=F6QCF6 F6QCF6 RENBP PTHR15108:SF0 N-ACYLGLUCOSAMINE-2-EPIMERASE N-ACYLGLUCOSAMINE 2-EPIMERASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;isomerase activity#GO:0016853 epimerase/racemase#PC00096 MONDO|Ensembl=ENSMODG00000018887.4|UniProtKB=F7CR95 F7CR95 ANKRD50 PTHR24123:SF65 ANKYRIN REPEAT-CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 50 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000048277.1|UniProtKB=F7FQM8 F7FQM8 PTHR26450:SF7 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017486.3|UniProtKB=F7FEX5 F7FEX5 PTHR11875:SF67 TESTIS-SPECIFIC Y-ENCODED PROTEIN PROTEIN SET protein binding#GO:0005515;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000040659.1|UniProtKB=A0A5F8GGB9 A0A5F8GGB9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000002186.3|UniProtKB=A0A5F8H348 A0A5F8H348 PTHR10969:SF114 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN-LIKE 2 lipid binding#GO:0008289;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;phospholipid binding#GO:0005543;ubiquitin-like protein ligase binding#GO:0044389 response to stimulus#GO:0050896;catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;cellular component disassembly#GO:0022411;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925;cellular response to stress#GO:0033554;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;autophagosome membrane#GO:0000421;autophagosome#GO:0005776;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000001582.4|UniProtKB=F7BWV8 F7BWV8 BZW2 PTHR14208:SF7 BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN EIF5-MIMIC PROTEIN 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 MONDO|Ensembl=ENSMODG00000003599.3|UniProtKB=A0A5F8GXQ3 A0A5F8GXQ3 PCK2 PTHR11561:SF11 PHOSPHOENOLPYRUVATE CARBOXYKINASE PHOSPHOENOLPYRUVATE CARBOXYKINASE [GTP], MITOCHONDRIAL transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;lyase activity#GO:0016829;metal ion binding#GO:0046872;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 response to nitrogen compound#GO:1901698;system development#GO:0048731;carbohydrate metabolic process#GO:0005975;homeostatic process#GO:0042592;cellular response to peptide hormone stimulus#GO:0071375;hexose biosynthetic process#GO:0019319;response to starvation#GO:0042594;intracellular chemical homeostasis#GO:0055082;cellular developmental process#GO:0048869;developmental process#GO:0032502;small molecule biosynthetic process#GO:0044283;cellular response to nitrogen compound#GO:1901699;tissue development#GO:0009888;response to nutrient levels#GO:0031667;intracellular glucose homeostasis#GO:0001678;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;carbohydrate homeostasis#GO:0033500;response to endogenous stimulus#GO:0009719;response to hexose#GO:0009746;carboxylic acid metabolic process#GO:0019752;animal organ development#GO:0048513;glucose metabolic process#GO:0006006;chemical homeostasis#GO:0048878;cellular response to glucose stimulus#GO:0071333;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;response to chemical#GO:0042221;response to lipid#GO:0033993;gluconeogenesis#GO:0006094;response to hormone#GO:0009725;response to stress#GO:0006950;anatomical structure development#GO:0048856;response to steroid hormone#GO:0048545;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular homeostasis#GO:0019725;cellular response to insulin stimulus#GO:0032869;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;response to peptide hormone#GO:0043434;epithelium development#GO:0060429;response to glucose#GO:0009749;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;response to carbohydrate#GO:0009743;cellular response to chemical stimulus#GO:0070887;response to monosaccharide#GO:0034284;animal gross anatomical part developmental process#GO:0160108;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;liver development#GO:0001889;glucose homeostasis#GO:0042593;multicellular organism development#GO:0007275;cellular response to steroid hormone stimulus#GO:0071383;alcohol metabolic process#GO:0006066;carbohydrate biosynthetic process#GO:0016051;cellular response to lipid#GO:0071396;alcohol biosynthetic process#GO:0046165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000018291.4|UniProtKB=F6PW91 F6PW91 CASR PTHR24061:SF358 CALCIUM-SENSING RECEPTOR-RELATED EXTRACELLULAR CALCIUM-SENSING RECEPTOR G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;metal ion binding#GO:0046872;cation binding#GO:0043169 response to calcium ion#GO:0051592;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;detection of chemical stimulus#GO:0009593;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;regulation of transport#GO:0051049;intracellular calcium ion homeostasis#GO:0006874;regulation of localization#GO:0032879;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;response to metal ion#GO:0010038;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;response to chemical#GO:0042221;regulation of monoatomic ion transport#GO:0043269;monoatomic ion homeostasis#GO:0050801;detection of stimulus#GO:0051606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016425.4|UniProtKB=F7ASR7 F7ASR7 ZSCAN32 PTHR23226:SF209 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 32 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000048858.1|UniProtKB=A0A5F8GP17 A0A5F8GP17 CNEP1R1 PTHR20996:SF1 NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000049184.1|UniProtKB=A0A5F8HIG2 A0A5F8HIG2 TMEM98 PTHR32510:SF3 TRANSMEMBRANE PROTEIN 98 TRANSMEMBRANE PROTEIN 98 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000007547.5|UniProtKB=F7G0J3 F7G0J3 DNAJB13 PTHR24078:SF553 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 13 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000013872.3|UniProtKB=F6W995 F6W995 PTHR46958:SF1 B-CELL RECEPTOR CD22 B-CELL RECEPTOR CD22 carbohydrate derivative binding#GO:0097367;protein phosphatase binding#GO:0019903;enzyme binding#GO:0019899;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;signaling receptor binding#GO:0005102;carboxylic acid binding#GO:0031406;binding#GO:0005488;small molecule binding#GO:0036094;phosphatase binding#GO:0019902;protein binding#GO:0005515 leukocyte activation#GO:0045321;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646;regulation of B cell receptor signaling pathway#GO:0050855;cell activation#GO:0001775;regulation of immune response#GO:0050776;regulation of cell population proliferation#GO:0042127;regulation of lymphocyte proliferation#GO:0050670;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of lymphocyte activation#GO:0051249;negative regulation of signaling#GO:0023057;immune system process#GO:0002376;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;regulation of mononuclear cell proliferation#GO:0032944;regulation of B cell activation#GO:0050864;cellular process#GO:0009987;lymphocyte activation#GO:0046649;negative regulation of signal transduction#GO:0009968;regulation of multicellular organismal process#GO:0051239;regulation of B cell proliferation#GO:0030888;regulation of leukocyte proliferation#GO:0070663;B cell activation#GO:0042113 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;external side of plasma membrane#GO:0009897;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell surface#GO:0009986;recycling endosome#GO:0055037 B cell activation#P00010>CD22#P00387 MONDO|Ensembl=ENSMODG00000015275.4|UniProtKB=A0A5F8HLD4 A0A5F8HLD4 NOD1 PTHR24106:SF18 NACHT, LRR AND CARD DOMAINS-CONTAINING NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-CONTAINING PROTEIN 1 molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187 response to bacterium#GO:0009617;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;positive regulation of signal transduction#GO:0009967;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of defense response#GO:0031349;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;regulation of signaling#GO:0023051;defense response to bacterium#GO:0042742;positive regulation of signaling#GO:0023056;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;positive regulation of response to external stimulus#GO:0032103;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017016.4|UniProtKB=F6QEZ5 F6QEZ5 ZGPAT PTHR46297:SF1 ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000028294.2|UniProtKB=A0A5F8HFV3 A0A5F8HFV3 PTHR11875:SF67 TESTIS-SPECIFIC Y-ENCODED PROTEIN PROTEIN SET binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393;protein binding#GO:0005515 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000003654.2|UniProtKB=F7AZ99 F7AZ99 PLEK PTHR12092:SF1 PLECKSTRIN PLECKSTRIN actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament-based process#GO:0030029;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000010197.3|UniProtKB=F6ST98 F6ST98 STEEP1 PTHR46355:SF1 UPF0428 PROTEIN CXORF56 STING ER EXIT PROTEIN endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;endoplasmic reticulum membrane organization#GO:0090158;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996 MONDO|Ensembl=ENSMODG00000000908.2|UniProtKB=A0A5F8GQA0 A0A5F8GQA0 LRIG2 PTHR24373:SF306 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;sensory perception of sound#GO:0007605;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000051477.1|UniProtKB=A0A5F8H9Q3 A0A5F8H9Q3 LOC103094754 PTHR24390:SF290 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 184 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000004186.4|UniProtKB=F6YA46 F6YA46 ARL6IP6 PTHR28640:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 6 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 6 MONDO|Ensembl=ENSMODG00000018715.4|UniProtKB=F7FCC2 F7FCC2 PRIM2 PTHR10537:SF3 DNA PRIMASE LARGE SUBUNIT DNA PRIMASE LARGE SUBUNIT RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;RNA metabolic process#GO:0016070;DNA-templated DNA replication#GO:0006261;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA replication initiation#GO:0006270 DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;transferase complex, transferring phosphorus-containing groups#GO:0061695;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;replisome#GO:0030894;nuclear DNA-directed RNA polymerase complex#GO:0055029;replication fork#GO:0005657;organelle#GO:0043226;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 primase#PC00189 DNA replication#P00017>Primase#P00528 MONDO|Ensembl=ENSMODG00000038697.1|UniProtKB=A0A5F8GL29 A0A5F8GL29 HOXA7 PTHR45659:SF12 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-A7 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502;anterior/posterior pattern specification#GO:0009952 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000010250.4|UniProtKB=F6W659 F6W659 SH3RF2 PTHR14167:SF60 SH3 DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE SH3RF2 molecular adaptor activity#GO:0060090;transferase activity#GO:0016740;protein phosphatase binding#GO:0019903;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;phosphatase binding#GO:0019902;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;regulation of JNK cascade#GO:0046328;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018556.4|UniProtKB=F7G2I3 F7G2I3 LRRK2 PTHR45752:SF7 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT SERINE_THREONINE-PROTEIN KINASE 2 MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cellular component organization#GO:0016043;regulation of autophagy#GO:0010506;endoplasmic reticulum organization#GO:0007029;regulation of biological process#GO:0050789;Golgi organization#GO:0007030;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of signaling#GO:0023051;positive regulation of metabolic process#GO:0009893;regulation of metabolic process#GO:0019222;regulation of canonical Wnt signaling pathway#GO:0060828;organelle organization#GO:0006996;positive regulation of autophagy#GO:0010508;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;endomembrane system organization#GO:0010256;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell projection organization#GO:0031344;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;regulation of endocytosis#GO:0030100;positive regulation of catabolic process#GO:0009896;cellular component organization or biogenesis#GO:0071840;regulation of catabolic process#GO:0009894;regulation of transport#GO:0051049;regulation of localization#GO:0032879 dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007624.4|UniProtKB=F7BLC2 F7BLC2 RELT PTHR47397:SF2 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 19L RELT TNF RECEPTOR programmed cell death#GO:0012501;cell death#GO:0008219;cellular process#GO:0009987;apoptotic process#GO:0006915 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019264.4|UniProtKB=A0A5F8GGK5 A0A5F8GGK5 PDLIM5 PTHR24214:SF32 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 5 protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;circulatory system development#GO:0072359;cellular component organization#GO:0016043;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;heart development#GO:0007507;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;myofibril#GO:0030016;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;stress fiber#GO:0001725;actin filament#GO:0005884;I band#GO:0031674;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;sarcomere#GO:0030017;cell junction#GO:0030054;adherens junction#GO:0005912;cell-cell junction#GO:0005911;Z disc#GO:0030018;actomyosin#GO:0042641;contractile muscle fiber#GO:0043292;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000045051.1|UniProtKB=A0A5F8HJF9 A0A5F8HJF9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000018360.4|UniProtKB=F6PPW0 F6PPW0 ITGB5 PTHR10082:SF26 INTEGRIN BETA SUBUNIT INTEGRIN BETA-5 integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102 actin filament organization#GO:0007015;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell adhesion mediated by integrin#GO:0033627;cell migration#GO:0016477;contractile actin filament bundle assembly#GO:0030038;biological regulation#GO:0065007;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;enzyme-linked receptor protein signaling pathway#GO:0007167;supramolecular fiber organization#GO:0097435;response to transforming growth factor beta#GO:0071559;actin filament-based process#GO:0030029;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;actin filament bundle assembly#GO:0051017;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;cellular component assembly#GO:0022607;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cytoskeleton organization#GO:0007010;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;cellular process#GO:0009987;stress fiber assembly#GO:0043149;cellular response to growth factor stimulus#GO:0071363;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;actomyosin structure organization#GO:0031032;response to endogenous stimulus#GO:0009719;cellular component organization#GO:0016043;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;actin filament bundle organization#GO:0061572 anchoring junction#GO:0070161;integrin complex#GO:0008305;cell junction#GO:0030054;signaling receptor complex#GO:0043235;cell-substrate junction#GO:0030055;plasma membrane#GO:0005886;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 MONDO|Ensembl=ENSMODG00000007342.4|UniProtKB=A0A5F8GED2 A0A5F8GED2 GRB2 PTHR46037:SF4 PROTEIN ENHANCER OF SEVENLESS 2B GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 protein binding#GO:0005515;growth factor receptor binding#GO:0070851;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cell communication#GO:0007154 plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cell periphery#GO:0071944;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;COP9 signalosome#GO:0008180;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 EGF receptor signaling pathway#P00018>Grb2#P00550;Angiogenesis#P00005>Grb2#P00252;T cell activation#P00053>Grb2#P01303;B cell activation#P00010>Grb2#P00372;FGF signaling pathway#P00021>Grb2#P00631;CCKR signaling map#P06959>GRB2#P07237;Integrin signalling pathway#P00034>Grb2#P00910;PDGF signaling pathway#P00047>Grb2#P01148;Ras Pathway#P04393>Grb2#P04544;Dopamine receptor mediated signaling pathway#P05912>Grb2#P05949;PI3 kinase pathway#P00048>Grb2#P01178;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Grb2#P00892;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Grb#P00848;Interleukin signaling pathway#P00036>Grb2#P00971;Gonadotropin-releasing hormone receptor pathway#P06664>Grb2#P06856;Nicotine pharmacodynamics pathway#P06587>Grb2#P06596;Angiogenesis#P00005>Grb2#P00234 MONDO|Ensembl=ENSMODG00000008172.2|UniProtKB=F7E5D5 F7E5D5 ZDHHC24 PTHR22883:SF414 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC24-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096 protein targeting#GO:0006605;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000010960.5|UniProtKB=F7BCA9 F7BCA9 PPP1R16A PTHR24179:SF30 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 16A enzyme inhibitor activity#GO:0004857;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000018826.3|UniProtKB=F6YYM0 F6YYM0 ANXA9 PTHR10502:SF122 ANNEXIN ANNEXIN A9 ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;phospholipid binding#GO:0005543;small molecule binding#GO:0036094;lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786 cellular process#GO:0009987;cell adhesion#GO:0007155 vesicle#GO:0031982;nucleus#GO:0005634;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000025311.2|UniProtKB=A0A5F8GSC8 A0A5F8GSC8 NYX PTHR24373:SF264 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN NYCTALOPIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000767.4|UniProtKB=F6SSU7 F6SSU7 PTHR10201:SF215 MATRIX METALLOPROTEINASE STROMELYSIN-1 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 catabolic process#GO:0009056;cellular process#GO:0009987;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;metabolic process#GO:0008152 metalloprotease#PC00153 CCKR signaling map#P06959>MMP3#P07105;Plasminogen activating cascade#P00050>pro-MMP-3#P01260;Plasminogen activating cascade#P00050>MMP-3#P01251 MONDO|Ensembl=ENSMODG00000002012.2|UniProtKB=F6QXR2 F6QXR2 PTHR15222:SF2 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 1 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 1 respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000048823.1|UniProtKB=A0A5F8GIL6 A0A5F8GIL6 PTHR35001:SF5 COLLAGEN IV NC1 DOMAIN-CONTAINING PROTEIN COLLAGEN IV NC1 DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000010352.3|UniProtKB=F6RP87 F6RP87 LOC100030313 PTHR26453:SF154 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037020.1|UniProtKB=K7E3D1 K7E3D1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024736.2|UniProtKB=A0A5F8HAS1 A0A5F8HAS1 ATF3 PTHR23351:SF23 FOS TRANSCRIPTION FACTOR-RELATED CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-3 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302;Gonadotropin-releasing hormone receptor pathway#P06664>Atf3#G06902;Gonadotropin-releasing hormone receptor pathway#P06664>Atf3#G06689;Gonadotropin-releasing hormone receptor pathway#P06664>Atf3#P06821 MONDO|Ensembl=ENSMODG00000013009.3|UniProtKB=A0A5F8GPA0 A0A5F8GPA0 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009874.4|UniProtKB=A0A5F8G500 A0A5F8G500 ATP2B1 PTHR24093:SF245 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 1 monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657 calcium ion homeostasis#GO:0055074;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cytosolic calcium ion concentration#GO:0051480;homeostatic process#GO:0042592 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000041919.1|UniProtKB=A0A5F8G369 A0A5F8G369 PTHR12022:SF0 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 7 oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987 membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex III#GO:0045275 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000008731.4|UniProtKB=A0A5F8GP07 A0A5F8GP07 RPL10 PTHR11726:SF10 60S RIBOSOMAL PROTEIN L10 LARGE RIBOSOMAL SUBUNIT PROTEIN UL16 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000040363.1|UniProtKB=A0A5F8H545 A0A5F8H545 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000008123.4|UniProtKB=F7ELV9 F7ELV9 PDE7A PTHR11347:SF96 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 7A cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794 phosphodiesterase#PC00185;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000016618.4|UniProtKB=A0A5F8G9V1 A0A5F8G9V1 FGFR1OP2 PTHR12186:SF3 SIKE FAMILY MEMBER FGFR1 ONCOGENE PARTNER 2 response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950 MONDO|Ensembl=ENSMODG00000015589.4|UniProtKB=F6ZUJ6 F6ZUJ6 SLC4A1AP PTHR23308:SF66 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 KANADAPTIN molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000023269.1|UniProtKB=F6TV72 F6TV72 LOC100032657 PTHR19424:SF3 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR-BINDING PROTEIN 1 cellular response to stress#GO:0033554;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950;heat acclimation#GO:0010286;response to heat#GO:0009408;cellular response to heat#GO:0034605;response to temperature stimulus#GO:0009266;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000028404.2|UniProtKB=K7E2L3 K7E2L3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000021112.4|UniProtKB=F6U2W0 F6U2W0 LANCL3 PTHR12736:SF29 LANC-LIKE PROTEIN LANC-LIKE PROTEIN 3 regulation of abscisic acid-activated signaling pathway#GO:0009787;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of response to alcohol#GO:1901419;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular response to alcohol#GO:1905957 MONDO|Ensembl=ENSMODG00000003240.4|UniProtKB=F6T1L2 F6T1L2 ACACA PTHR45728:SF5 ACETYL-COA CARBOXYLASE, ISOFORM A ACETYL-COA CARBOXYLASE 1 ligase activity#GO:0016874;catalytic activity#GO:0003824 monocarboxylic acid biosynthetic process#GO:0072330;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000044037.1|UniProtKB=A0A5F8G9P0 A0A5F8G9P0 SAC3D1 PTHR12436:SF38 80 KDA MCM3-ASSOCIATED PROTEIN SAC3 DOMAIN-CONTAINING PROTEIN 1 mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;chromosome segregation#GO:0007059;metabolic process#GO:0008152;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleocytoplasmic transport#GO:0006913;organelle assembly#GO:0070925;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;cell cycle#GO:0007049;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;establishment of localization#GO:0051234;spindle organization#GO:0007051;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transcription export complex 2#GO:0070390;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;cytoskeleton#GO:0005856 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000008598.4|UniProtKB=F7BTY5 F7BTY5 GEMIN5 PTHR46362:SF1 GEM-ASSOCIATED PROTEIN 5 GEM-ASSOCIATED PROTEIN 5 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;SMN complex#GO:0032797;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000039640.1|UniProtKB=A0A5F8GTT2 A0A5F8GTT2 PTHR11227:SF27 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 2 phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936 polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;polysaccharide catabolic process#GO:0000272;carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;localization#GO:0051179;vacuole organization#GO:0007033;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;macroautophagy#GO:0016236;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036;energy derivation by oxidation of organic compounds#GO:0015980;pexophagy#GO:0000425;macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091 phagophore assembly site#GO:0000407;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000533.4|UniProtKB=A0A5F8GWW1 A0A5F8GWW1 DDX18 PTHR24031:SF301 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX18 rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000038634.1|UniProtKB=F7FZ41 F7FZ41 LOC100619724 PTHR26451:SF52 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 12D2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000007743.4|UniProtKB=F7BKB4 F7BKB4 TRIM47 PTHR25465:SF21 B-BOX DOMAIN CONTAINING E3 UBIQUITIN-PROTEIN LIGASE TRIM47 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000018626.3|UniProtKB=F7B2Z7 F7B2Z7 PTHR22237:SF2 APC MEMBRANE RECRUITMENT PROTEIN 2-RELATED APC MEMBRANE RECRUITMENT PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000019891.5|UniProtKB=A0A5F8GL02 A0A5F8GL02 AMBRA1 PTHR22874:SF1 ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1 ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;cellular component organization#GO:0016043;catabolic process#GO:0009056;organelle assembly#GO:0070925;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000010897.5|UniProtKB=F7FJ41 F7FJ41 KIAA2013 PTHR31386:SF2 UNCHARACTERIZED PROTEIN KIAA2013 RIKEN CDNA 2510039O18 GENE LIKE MONDO|Ensembl=ENSMODG00000012633.4|UniProtKB=F6WU66 F6WU66 INVS PTHR24178:SF2 MOLTING PROTEIN MLT-4 INVERSIN intracellular protein localization#GO:0008104;system development#GO:0048731;localization#GO:0051179;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;multicellular organismal process#GO:0032501;kidney development#GO:0001822;macromolecule localization#GO:0033036;renal system development#GO:0072001 cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000019188.4|UniProtKB=F7A9K2 F7A9K2 LOC100023783 PTHR12015:SF192 SMALL INDUCIBLE CYTOKINE A GROWTH-REGULATED ALPHA PROTEIN cytokine#PC00083 CCKR signaling map#P06959>CXCL1#G07268;CCKR signaling map#P06959>CXCL1#G06975 MONDO|Ensembl=ENSMODG00000003634.4|UniProtKB=F7BM63 F7BM63 FOCAD PTHR16212:SF4 FOCADHESIN FAMILY MEMBER FOCADHESIN MONDO|Ensembl=ENSMODG00000013750.2|UniProtKB=F6WS80 F6WS80 FMC1 PTHR31716:SF1 PROTEIN FMC1 HOMOLOG PROTEIN FMC1 HOMOLOG protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000000121.4|UniProtKB=A0A5F8GGX2 A0A5F8GGX2 P4HA1 PTHR10869:SF101 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-1 dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;oxidoreductase complex#GO:1990204;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000042098.1|UniProtKB=A0A5F8G9R2 A0A5F8G9R2 PTHR35157:SF1 PROTEIN FAM209A PROTEIN FAM209A MONDO|Ensembl=ENSMODG00000043428.1|UniProtKB=A0A5F8GB54 A0A5F8GB54 PTHR11267:SF125 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX21 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 mononuclear cell migration#GO:0071674;immune system process#GO:0002376;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;leukocyte migration#GO:0050900;cell fate specification#GO:0001708;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;lymphocyte migration#GO:0072676;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cell migration#GO:0016477;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 MONDO|Ensembl=ENSMODG00000021510.4|UniProtKB=F7FSI0 F7FSI0 SS18 PTHR23107:SF2 SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN PROTEIN SSXT transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000005327.4|UniProtKB=F7D238 F7D238 PTHR23187:SF3 FLJ44216 PROTEIN-RELATED SUMO-INTERACTING MOTIF-CONTAINING PROTEIN 1 molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;peptidase inhibitor activity#GO:0030414 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 MONDO|Ensembl=ENSMODG00000016970.4|UniProtKB=A0A5F8GJW2 A0A5F8GJW2 ARHGEF2 PTHR13944:SF20 AGAP007712-PA RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;regulation of small GTPase mediated signal transduction#GO:0051056;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;small GTPase-mediated signal transduction#GO:0007264;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;actin filament-based process#GO:0030029;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;actin cytoskeleton organization#GO:0030036;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052 leading edge membrane#GO:0031256;intracellular organelle#GO:0043229;cell projection membrane#GO:0031253;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;ruffle membrane#GO:0032587;cytoskeleton#GO:0005856;ruffle#GO:0001726;membraneless organelle#GO:0043228;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000018787.4|UniProtKB=F6WTA1 F6WTA1 HCRTR2 PTHR24241:SF75 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OREXIN RECEPTOR TYPE 2 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000002009.4|UniProtKB=F6QXS1 F6QXS1 ETFDH PTHR10617:SF107 ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;electron transfer activity#GO:0009055;catalytic activity#GO:0003824 electron transport chain#GO:0022900;metabolic process#GO:0008152;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000013711.4|UniProtKB=F6Y9F4 F6Y9F4 PLTP PTHR10504:SF16 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED PHOSPHOLIPID TRANSFER PROTEIN transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;ceramide transport#GO:0035627;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;localization#GO:0051179;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biological regulation#GO:0065007;phospholipid transport#GO:0015914;multicellular organismal process#GO:0032501;lipid transport#GO:0006869;transport#GO:0006810;protein-containing complex organization#GO:0043933;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000006335.4|UniProtKB=F7AGC0 F7AGC0 RPL32 PTHR47225:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 12 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 12 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000009636.4|UniProtKB=F6QTV6 F6QTV6 KL PTHR10353:SF10 GLYCOSYL HYDROLASE KLOTHO hydrolase activity, acting on glycosyl bonds#GO:0016798;fibroblast growth factor receptor binding#GO:0005104;fibroblast growth factor binding#GO:0017134;growth factor receptor binding#GO:0070851;beta-glucosidase activity#GO:0008422;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;protein binding#GO:0005515;growth factor binding#GO:0019838;glucosidase activity#GO:0015926;binding#GO:0005488;signaling receptor binding#GO:0005102 response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;signaling#GO:0023052;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;signal transduction#GO:0007165;fibroblast growth factor receptor signaling pathway#GO:0008543;biological regulation#GO:0065007;response to fibroblast growth factor#GO:0071774;cell surface receptor signaling pathway#GO:0007166 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000005160.4|UniProtKB=A0A5F8GEA8 A0A5F8GEA8 TRIM45 PTHR25462:SF291 BONUS, ISOFORM C-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM45 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000028811.1|UniProtKB=K7DZ34 K7DZ34 PTHR37492:SF4 SI:CH211-171H4.7-RELATED INWARD RECTIFIER POTASSIUM CHANNEL 13 ISOFORM X1 MONDO|Ensembl=ENSMODG00000011627.4|UniProtKB=F6U139 F6U139 IRAK1 PTHR24419:SF1 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1 protein serine/threonine kinase activity#GO:0004674;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173 regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;cellular response to lipid#GO:0071396;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;cellular response to oxygen-containing compound#GO:1901701;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;immune response-activating signaling pathway#GO:0002757;response to lipopolysaccharide#GO:0032496;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;immune response-regulating signaling pathway#GO:0002764;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of innate immune response#GO:0045088;innate immune response#GO:0045087;positive regulation of response to biotic stimulus#GO:0002833;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646;cell cycle#GO:0007049;positive regulation of signal transduction#GO:0009967;innate immune response-activating signaling pathway#GO:0002758;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;cytokine-mediated signaling pathway#GO:0019221;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to lipid#GO:0033993;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of response to external stimulus#GO:0032103;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;toll-like receptor 4 signaling pathway#GO:0034142;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;regulation of response to stress#GO:0080134;positive regulation of intracellular signal transduction#GO:1902533;mitotic cell cycle#GO:0000278;positive regulation of cell communication#GO:0010647;response to external biotic stimulus#GO:0043207;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of response to biotic stimulus#GO:0002831;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;lipopolysaccharide-mediated signaling pathway#GO:0031663;response to bacterium#GO:0009617 membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>IRAK1#P01343 MONDO|Ensembl=ENSMODG00000029280.2|UniProtKB=K7E527 K7E527 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003016.4|UniProtKB=F6Q2Q1 F6Q2Q1 ARHGAP15 PTHR23176:SF108 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 15 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 MONDO|Ensembl=ENSMODG00000048060.1|UniProtKB=A0A5F8GAD2 A0A5F8GAD2 PTHR12489:SF13 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 3 PROTEIN nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000016750.3|UniProtKB=A0A5F8H964 A0A5F8H964 RMND1 PTHR16255:SF1 REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein metabolic process#GO:0051247;positive regulation of translation#GO:0045727;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 MONDO|Ensembl=ENSMODG00000027541.2|UniProtKB=K7E1W5 K7E1W5 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED RETROVIRAL ENVELOPE PROTEIN GP41-LIKE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000044895.1|UniProtKB=A0A5F8GNW1 A0A5F8GNW1 CFAP90 PTHR34444:SF1 LOC361192 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 90 MONDO|Ensembl=ENSMODG00000048171.1|UniProtKB=A0A5F8G434 A0A5F8G434 PTHR48188:SF3 60S RIBOSOMAL PROTEIN L43 60S RIBOSOMAL PROTEIN L37A intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000005474.3|UniProtKB=F7CG88 F7CG88 ITPA PTHR11067:SF9 INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN INOSINE TRIPHOSPHATE PYROPHOSPHATASE hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;nucleoside triphosphate diphosphatase activity#GO:0047429 nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate catabolic process#GO:0046434;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;cellular process#GO:0009987;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 nucleotide phosphatase#PC00173 MONDO|Ensembl=ENSMODG00000014504.4|UniProtKB=A0A5F8GSP2 A0A5F8GSP2 POU2AF1 PTHR15363:SF3 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000006958.3|UniProtKB=F6QW29 F6QW29 PTHR24068:SF543 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 D3 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein K11-linked ubiquitination#GO:0070979;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000020072.4|UniProtKB=F7GID7 F7GID7 ERAP1 PTHR11533:SF156 PROTEASE M1 ZINC METALLOPROTEASE ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1 metallopeptidase activity#GO:0008237;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metalloexopeptidase activity#GO:0008235;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;peptide catabolic process#GO:0043171;primary metabolic process#GO:0044238 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000041388.1|UniProtKB=A0A5F8GMH8 A0A5F8GMH8 LOC100025151 PTHR26453:SF255 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027776.2|UniProtKB=K7E183 K7E183 LOC103105936 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000019692.4|UniProtKB=A0A5F8GBM1 A0A5F8GBM1 PTHR11903:SF6 PROSTAGLANDIN G/H SYNTHASE PROSTAGLANDIN G_H SYNTHASE 1 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 carboxylic acid biosynthetic process#GO:0046394;arachidonate metabolic process#GO:0019369;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;prostaglandin metabolic process#GO:0006693;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;fatty acid biosynthetic process#GO:0006633;icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;unsaturated fatty acid biosynthetic process#GO:0006636;lipid biosynthetic process#GO:0008610;icosanoid metabolic process#GO:0006690;unsaturated fatty acid metabolic process#GO:0033559;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;neuron projection#GO:0043005 oxygenase#PC00177;oxidoreductase#PC00176 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cyclooxygenase#P00845 MONDO|Ensembl=ENSMODG00000001949.4|UniProtKB=F6VJQ9 F6VJQ9 NR2E3 PTHR24083:SF4 NUCLEAR HORMONE RECEPTOR PHOTORECEPTOR-SPECIFIC NUCLEAR RECEPTOR transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 developmental process#GO:0032502;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000004026.4|UniProtKB=F7D6F9 F7D6F9 PTHR12329:SF52 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 Apoptosis signaling pathway#P00006>Bag#P00278 MONDO|Ensembl=ENSMODG00000010476.4|UniProtKB=F7ET02 F7ET02 PIF1 PTHR23274:SF11 DNA HELICASE-RELATED ATP-DEPENDENT DNA HELICASE PIF1 macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 DNA helicase#PC00011 MONDO|Ensembl=ENSMODG00000006701.3|UniProtKB=A0A5F8GEQ9 A0A5F8GEQ9 CEP170 PTHR15715:SF17 CENTROSOMAL PROTEIN OF 170 KDA CENTROSOMAL PROTEIN OF 170 KDA protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 microtubule cytoskeleton organization#GO:0000226;microtubule anchoring#GO:0034453;cellular component organization or biogenesis#GO:0071840;microtubule anchoring at microtubule organizing center#GO:0072393;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cytoskeleton organization#GO:0007010 centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000046939.1|UniProtKB=H9H8F2 H9H8F2 LOC100618142 PTHR48002:SF109 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K15 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010411.3|UniProtKB=F7A766 F7A766 PTHR22192:SF16 SPERIOLIN SPERIOLIN intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813 MONDO|Ensembl=ENSMODG00000000131.4|UniProtKB=A0A5F8H3Z7 A0A5F8H3Z7 CEP57 PTHR19336:SF11 UNCHARACTERIZED DUF1167 CENTROSOMAL PROTEIN OF 57 KDA microtubule binding#GO:0008017;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;cytoskeletal adaptor activity#GO:0008093;tubulin binding#GO:0015631;molecular adaptor activity#GO:0060090 cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;attachment of spindle microtubules to kinetochore#GO:0008608;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000040879.1|UniProtKB=A0A5F8GY47 A0A5F8GY47 IL2 PTHR48487:SF1 INTERLEUKIN-2 INTERLEUKIN-2 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;response to peptide#GO:1901652;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;interleukin-2-mediated signaling pathway#GO:0038110;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 Interleukin signaling pathway#P00036>Interleukin#P00970;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 MONDO|Ensembl=ENSMODG00000003999.4|UniProtKB=F7DRX5 F7DRX5 LPAR1 PTHR22750:SF22 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 1 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;developmental process#GO:0032502;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000018448.4|UniProtKB=F7CUF2 F7CUF2 CECR2 PTHR47092:SF1 CAT EYE SYNDROME CRITICAL REGION PROTEIN 2 CHROMATIN REMODELING REGULATOR CECR2 fertilization#GO:0009566;reproductive process#GO:0022414;single fertilization#GO:0007338;sexual reproduction#GO:0019953 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;ISWI-type complex#GO:0031010;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000008950.4|UniProtKB=F7GD01 F7GD01 RHOJ PTHR24072:SF17 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOJ nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;kinase binding#GO:0019900 cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;actin filament organization#GO:0007015;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;signaling#GO:0023052;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;localization#GO:0051179;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Huntington disease#P00029>Rac#P00775;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507;EGF receptor signaling pathway#P00018>Rac#P00564 MONDO|Ensembl=ENSMODG00000028819.2|UniProtKB=K7E298 K7E298 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000014862.2|UniProtKB=A0A5F8HKI1 A0A5F8HKI1 PTHR21297:SF0 DNA-DIRECTED RNA POLYMERASE II DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 binding#GO:0005488;protein binding#GO:0005515;translation initiation factor binding#GO:0031369 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 MONDO|Ensembl=ENSMODG00000014516.3|UniProtKB=A0A5F8GKM0 A0A5F8GKM0 MEST PTHR43139:SF52 SI:DKEY-122A22.2 MESODERM-SPECIFIC TRANSCRIPT PROTEIN protein modifying enzyme#PC00260;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000013410.4|UniProtKB=F7CNL5 F7CNL5 NCKIPSD PTHR13357:SF1 SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN NCK-INTERACTING PROTEIN WITH SH3 DOMAIN protein-containing complex binding#GO:0044877;binding#GO:0005488 localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;endocytosis#GO:0006897;transport#GO:0006810 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000008502.4|UniProtKB=F7FTG4 F7FTG4 SPATC1L PTHR22192:SF1 SPERIOLIN SPERIOLIN-LIKE PROTEIN intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000050064.1|UniProtKB=A0A5F8HF83 A0A5F8HF83 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002696.4|UniProtKB=F7CY56 F7CY56 CALM1 PTHR23048:SF63 MYOSIN LIGHT CHAIN 1, 3 CALMODULIN-LIKE 5 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000007442.4|UniProtKB=F7DW73 F7DW73 TRIM66 PTHR45915:SF7 TRANSCRIPTION INTERMEDIARY FACTOR TRIPARTITE MOTIF-CONTAINING PROTEIN 66 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transcription coregulator activity#GO:0003712;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;transcription regulator activity#GO:0140110 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000005209.2|UniProtKB=A0A5F8H9W0 A0A5F8H9W0 PTHR12755:SF6 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 mRNA polyadenylation factor#PC00146;RNA processing factor#PC00147;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000029231.2|UniProtKB=K7E306 K7E306 TOPAZ1 PTHR35671:SF1 PROTEIN TOPAZ1 PROTEIN TOPAZ1 spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;developmental process#GO:0032502;multicellular organismal reproductive process#GO:0048609;cellular process#GO:0009987;cell division#GO:0051301;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;male gamete generation#GO:0048232;gamete generation#GO:0007276 MONDO|Ensembl=ENSMODG00000024576.3|UniProtKB=F7BTA9 F7BTA9 LOC100618883 PTHR48018:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 974 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003438.3|UniProtKB=F7DX20 F7DX20 FBXL7 PTHR13318:SF50 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 7 MONDO|Ensembl=ENSMODG00000025281.2|UniProtKB=F7A2R1 F7A2R1 PTHR12391:SF11 ARP2/3 COMPLEX 21 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 3 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 organelle organization#GO:0006996;cellular component organization#GO:0016043;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876 MONDO|Ensembl=ENSMODG00000002680.4|UniProtKB=F7AZJ1 F7AZJ1 EIF4E2 PTHR11960:SF17 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 2 nucleic acid binding#GO:0003676;binding#GO:0005488;translation factor activity#GO:0180051;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 MONDO|Ensembl=ENSMODG00000005544.4|UniProtKB=F6TGT0 F6TGT0 PTHR10913:SF71 FOLLISTATIN-RELATED SERINE PROTEASE INHIBITOR KAZAL-TYPE 5 peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;developmental process#GO:0032502;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000002266.3|UniProtKB=F7CW50 F7CW50 PTHR11905:SF136 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 9 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 animal gross anatomical part developmental process#GO:0160108;proteolysis#GO:0006508;reproductive system development#GO:0061458;system development#GO:0048731;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;reproductive structure development#GO:0048608;reproductive process#GO:0022414;male sex differentiation#GO:0046661;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;metabolic process#GO:0008152;development of primary male sexual characteristics#GO:0046546;animal organ development#GO:0048513;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;sex differentiation#GO:0007548;cellular process#GO:0009987;male gonad development#GO:0008584;gonad development#GO:0008406;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane region#GO:0098590;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 protease#PC00190;metalloprotease#PC00153 Alzheimer disease-amyloid secretase pathway#P00003>MDC9#P00090 MONDO|Ensembl=ENSMODG00000025348.1|UniProtKB=F6YLY5 F6YLY5 LOC130455815 PTHR28632:SF2 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7 MONDO|Ensembl=ENSMODG00000012271.4|UniProtKB=F6YG84 F6YG84 MFSD8 PTHR23510:SF83 INNER MEMBRANE TRANSPORT PROTEIN YAJR MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 8 monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509 catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;cellular component disassembly#GO:0022411;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;macroautophagy#GO:0016236;organelle organization#GO:0006996;autophagy#GO:0006914;lysosome organization#GO:0007040;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;autophagosome maturation#GO:0097352;lytic vacuole organization#GO:0080171 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765 MONDO|Ensembl=ENSMODG00000011651.4|UniProtKB=F6YES1 F6YES1 BTK PTHR24418:SF92 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE BTK phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;non-membrane spanning protein tyrosine kinase activity#GO:0004715;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 B cell activation#P00010>Btk#P00400 MONDO|Ensembl=ENSMODG00000013280.4|UniProtKB=A0A5F8GT54 A0A5F8GT54 C2CD2L PTHR21119:SF8 C2 DOMAIN-CONTAINING PROTEIN PHOSPHOLIPID TRANSFER PROTEIN C2CD2L small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;molecular carrier activity#GO:0140104;ion binding#GO:0043167;lipid carrier activity#GO:0005319;lipid transfer activity#GO:0120013;phosphatidylinositol binding#GO:0035091;transporter activity#GO:0005215;phosphatidylinositol transfer activity#GO:0008526 regulation of hormone levels#GO:0010817;regulation of protein secretion#GO:0050708;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;positive regulation of secretion#GO:0051047;positive regulation of hormone secretion#GO:0046887;positive regulation of signaling#GO:0023056;regulation of secretion#GO:0051046;regulation of hormone secretion#GO:0046883;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of insulin secretion#GO:0050796;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;positive regulation of protein secretion#GO:0050714;regulation of localization#GO:0032879;regulation of transport#GO:0051049 side of membrane#GO:0098552;apical part of cell#GO:0045177;cytoplasmic side of membrane#GO:0098562;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000037721.1|UniProtKB=A0A5F8GCG3 A0A5F8GCG3 CHODL PTHR14789:SF1 CHONDROLECTIN VARIANT CHODLFDELTAE. CHONDROLECTIN regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of axonogenesis#GO:0050770;regulation of cell projection organization#GO:0031344;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;biological regulation#GO:0065007;regulation of cell development#GO:0060284;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;regulation of nervous system development#GO:0051960;positive regulation of axonogenesis#GO:0050772;positive regulation of cell projection organization#GO:0031346;positive regulation of cellular component organization#GO:0051130;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000000766.3|UniProtKB=A0A5F8GET8 A0A5F8GET8 PTHR24070:SF269 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN DI-RAS3 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000019593.4|UniProtKB=A0A5F8GYP0 A0A5F8GYP0 NTRK3 PTHR24416:SF66 TYROSINE-PROTEIN KINASE RECEPTOR NT-3 GROWTH FACTOR RECEPTOR transferase activity#GO:0016740;kinase activity#GO:0016301;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular response to nerve growth factor stimulus#GO:1990090;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 signaling receptor complex#GO:0043235;axon#GO:0030424;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000044607.1|UniProtKB=A0A5F8GZC0 A0A5F8GZC0 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000015137.4|UniProtKB=F7D009 F7D009 ATP13A4 PTHR45630:SF1 CATION-TRANSPORTING ATPASE-RELATED CATION-TRANSPORTING ATPASE 13A4-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;polyamine transmembrane transporter activity#GO:0015203 cellular process#GO:0009987;nitrogen compound transport#GO:0071705;monoatomic ion homeostasis#GO:0050801;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;transmembrane transport#GO:0055085;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074 membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783;late endosome membrane#GO:0031902;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000050639.1|UniProtKB=A0A5F8HJB5 A0A5F8HJB5 monDomV1R1209 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023358.2|UniProtKB=F6Y3Y9 F6Y3Y9 OR52W1 PTHR26450:SF58 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52W1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016719.4|UniProtKB=F7CHI9 F7CHI9 ESR1 PTHR48092:SF16 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN RECEPTOR sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to steroid hormone#GO:0048545;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;steroid hormone receptor signaling pathway#GO:0043401;cellular response to stimulus#GO:0051716;intracellular receptor signaling pathway#GO:0030522;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to steroid hormone stimulus#GO:0071383;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;estrogen receptor signaling pathway#GO:0030520;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to hormone stimulus#GO:0032870 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000020068.3|UniProtKB=F7GIJ2 F7GIJ2 LOC100024664 PTHR48018:SF129 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 9G4 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006509.3|UniProtKB=F7EJX3 F7EJX3 LDHC PTHR43128:SF10 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A CHAIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;monocarboxylic acid catabolic process#GO:0072329;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000019120.4|UniProtKB=F7EV69 F7EV69 LOC100020842 PTHR12015:SF103 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 4-LIKE signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677 positive regulation of cell motility#GO:2000147;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to peptide#GO:1901652;response to stress#GO:0006950;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;taxis#GO:0042330;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;cell surface receptor signaling pathway#GO:0007166;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;cytokine-mediated signaling pathway#GO:0019221;inflammatory response#GO:0006954;chemotaxis#GO:0006935;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cell chemotaxis#GO:0060326;positive regulation of cell migration#GO:0030335;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;cell migration#GO:0016477;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;positive regulation of locomotion#GO:0040017 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000051590.1|UniProtKB=K7E1M3 K7E1M3 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000019364.4|UniProtKB=F6WTI9 F6WTI9 SEC11A PTHR10806:SF28 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11A peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;cytoplasm#GO:0005737;peptidase complex#GO:1905368;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 serine protease#PC00203 Endothelin signaling pathway#P00019>signal peptidase#P00573;Vasopressin synthesis#P04395>Signal Peptidase#P04589 MONDO|Ensembl=ENSMODG00000019706.4|UniProtKB=F6TBV7 F6TBV7 THBS4 PTHR10199:SF92 THROMBOSPONDIN THROMBOSPONDIN-4 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;response to stress#GO:0006950;response to endoplasmic reticulum stress#GO:0034976;response to stimulus#GO:0050896 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000019078.4|UniProtKB=F7FNM9 F7FNM9 CRYZ PTHR44154:SF1 QUINONE OXIDOREDUCTASE ZETA-CRYSTALLIN RNA binding#GO:0003723;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;binding#GO:0005488;mRNA binding#GO:0003729;nucleoside phosphate binding#GO:1901265;mRNA 3'-UTR binding#GO:0003730;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Huntington disease#P00029>PIG3#G01535 MONDO|Ensembl=ENSMODG00000017716.4|UniProtKB=F7FHS3 F7FHS3 RNF217 PTHR11685:SF479 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF217 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;binding#GO:0005488;acyltransferase activity#GO:0016746;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000014500.4|UniProtKB=F7F778 F7F778 PSMC6 PTHR23073:SF31 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 10B polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;isomerase activity#GO:0016853 positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription initiation#GO:2000142;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;response to endoplasmic reticulum stress#GO:0034976;regulation of RNA metabolic process#GO:0051252;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular component organization#GO:0051128;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;positive regulation of cellular component organization#GO:0051130;protein catabolic process#GO:0030163;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;proteasome complex#GO:0000502;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000042094.1|UniProtKB=A0A5F8GK67 A0A5F8GK67 PTHR23050:SF427 CALCIUM BINDING PROTEIN CALMODULIN-3 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;cation binding#GO:0043169;kinase activator activity#GO:0019209;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 cellular response to stimulus#GO:0051716;detection of chemical stimulus#GO:0009593;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762;calcineurin-mediated signaling#GO:0097720;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to calcium ion#GO:0051592;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;signal transduction#GO:0007165;detection of stimulus#GO:0051606;intracellular signaling cassette#GO:0141124;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;response to chemical#GO:0042221;regulation of monoatomic ion transport#GO:0043269;response to metal ion#GO:0010038;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of release of sequestered calcium ion into cytosol#GO:0051279;calcium-mediated signaling#GO:0019722;regulation of localization#GO:0032879;regulation of transport#GO:0051049 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;myelin sheath#GO:0043209;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 calmodulin-related#PC00061;calcium-binding protein#PC00060 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 MONDO|Ensembl=ENSMODG00000016358.3|UniProtKB=F7F6U0 F7F6U0 KCNG1 PTHR11537:SF88 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL REGULATORY SUBUNIT KCNG1 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;ion channel regulator activity#GO:0099106 metal ion transport#GO:0030001;action potential#GO:0001508;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000051256.1|UniProtKB=F6Z372 F6Z372 CRYGD PTHR11818:SF145 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN D structural molecule activity#GO:0005198 visual perception#GO:0007601;visual system development#GO:0150063;sensory perception of light stimulus#GO:0050953;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;multicellular organism development#GO:0007275;animal organ development#GO:0048513;system process#GO:0003008;sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000023733.2|UniProtKB=F6Y8V7 F6Y8V7 SLC25A53 PTHR46131:SF5 SD08549P SOLUTE CARRIER FAMILY 25 MEMBER 53 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;purine nucleotide transmembrane transporter activity#GO:0015216;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000001517.5|UniProtKB=K7E0B1 K7E0B1 ARMC5 PTHR23312:SF8 ARMC5 ARMADILLO REPEAT-CONTAINING -RELATED ARMADILLO REPEAT-CONTAINING PROTEIN 5 anatomical structure development#GO:0048856;developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653 MONDO|Ensembl=ENSMODG00000019737.4|UniProtKB=F6X3V6 F6X3V6 DENND1A PTHR13196:SF22 DENN DOMAIN-CONTAINING DENN DOMAIN-CONTAINING PROTEIN 1A lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488;phospholipid binding#GO:0005543 endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular localization#GO:0051641;localization within membrane#GO:0051668;transport#GO:0006810;intracellular transport#GO:0046907;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular organelle#GO:0043229;clathrin-coated vesicle#GO:0030136;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;cytosol#GO:0005829;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000019429.4|UniProtKB=F6SFL4 F6SFL4 BCL2A1 PTHR11256:SF10 BCL-2 RELATED BCL-2-RELATED PROTEIN A1 channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;programmed cell death#GO:0012501;mitochondrial fusion#GO:0008053;cellular response to stimulus#GO:0051716;cell death#GO:0008219;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;apoptotic signaling pathway#GO:0097190;positive regulation of cellular process#GO:0048522;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway#GO:0097193;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;release of cytochrome c from mitochondria#GO:0001836;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;organelle fusion#GO:0048284;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005 mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Apoptosis signaling pathway#P00006>A1#P00283 MONDO|Ensembl=ENSMODG00000010324.4|UniProtKB=F6S9W3 F6S9W3 SUV39H1 PTHR46223:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H1 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;lysine N-methyltransferase activity#GO:0016278;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000045589.1|UniProtKB=A0A5F8GQ12 A0A5F8GQ12 LOC130453489 PTHR24384:SF261 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 719 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000011261.3|UniProtKB=F6R191 F6R191 EXOSC7 PTHR11097:SF8 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP42 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;rRNA metabolic process#GO:0016072;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494 exoribonuclease#PC00099;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000018988.4|UniProtKB=F7FP03 F7FP03 KLC4 PTHR45783:SF6 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 4 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 microtubule binding motor protein#PC00156 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 MONDO|Ensembl=ENSMODG00000012674.4|UniProtKB=F6VGY3 F6VGY3 WFIKKN2 PTHR45938:SF7 ACP24A4-RELATED WAP, KAZAL, IMMUNOGLOBULIN, KUNITZ AND NTR DOMAIN-CONTAINING PROTEIN 2 growth factor binding#GO:0019838;protein binding#GO:0005515;signaling receptor inhibitor activity#GO:0030547;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;cytokine binding#GO:0019955;molecular function regulator activity#GO:0098772;transforming growth factor beta binding#GO:0050431;signaling receptor regulator activity#GO:0030545 cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;response to transforming growth factor beta#GO:0071559;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000011632.5|UniProtKB=F6TJV4 F6TJV4 PPM1M PTHR13832:SF236 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1M hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000000524.4|UniProtKB=A0A5F8H4N8 A0A5F8H4N8 GGA1 PTHR45905:SF4 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1 enzyme binding#GO:0019899;binding#GO:0005488;small GTPase binding#GO:0031267;protein binding#GO:0005515 transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization within membrane#GO:0051668;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;post-Golgi vesicle-mediated transport#GO:0006892;macromolecule localization#GO:0033036;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;Golgi to plasma membrane transport#GO:0006893 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000002493.4|UniProtKB=F7BVL7 F7BVL7 DDX52 PTHR24031:SF594 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX52-RELATED biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000016363.4|UniProtKB=A0A5F8GT26 A0A5F8GT26 NFATC2 PTHR12533:SF4 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;calcium-mediated signaling#GO:0019722;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;calcineurin-mediated signaling#GO:0097720;calcineurin-NFAT signaling cascade#GO:0033173;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252;gene-specific transcriptional regulator#PC00264 Axon guidance mediated by netrin#P00009>NFAT#P00359;T cell activation#P00053>NFAT#P01294;B cell activation#P00010>NFAT#P00367;Wnt signaling pathway#P00057>NFAT#P01452;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851;Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;CCKR signaling map#P06959>NFAT1#P07176 MONDO|Ensembl=ENSMODG00000025173.2|UniProtKB=F7FXG0 F7FXG0 LOC100616968 PTHR47979:SF3 DRAB11-RELATED RAS-RELATED PROTEIN RAB-39A catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;cellular component biogenesis#GO:0044085;membrane fusion#GO:0061025;organelle organization#GO:0006996;lysosome organization#GO:0007040;cellular process#GO:0009987;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;phagocytosis#GO:0006909;phagolysosome assembly#GO:0001845;lytic vacuole organization#GO:0080171;transport#GO:0006810;endocytosis#GO:0006897;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;localization#GO:0051179;vacuole organization#GO:0007033;organelle assembly#GO:0070925 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000042566.1|UniProtKB=A0A5F8GVQ1 A0A5F8GVQ1 LOC100617881 PTHR38503:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 1 SMALL INTEGRAL MEMBRANE PROTEIN 1 immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;erythrocyte differentiation#GO:0030218;multicellular organismal-level homeostasis#GO:0048871;cellular process#GO:0009987;multicellular organismal process#GO:0032501;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;cell development#GO:0048468;homeostatic process#GO:0042592;hemopoiesis#GO:0030097 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000011199.4|UniProtKB=F6SRE0 F6SRE0 SPCS1 PTHR13202:SF0 MICROSOMAL SIGNAL PEPTIDASE 12 KDA SUBUNIT SIGNAL PEPTIDASE COMPLEX SUBUNIT 1 primary metabolic process#GO:0044238;protein targeting#GO:0006605;protein metabolic process#GO:0019538;localization#GO:0051179;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of protein localization#GO:0045184;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;establishment of protein localization to endoplasmic reticulum#GO:0072599;metabolic process#GO:0008152;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047 membrane#GO:0016020;peptidase complex#GO:1905368;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protease#PC00190 Vasopressin synthesis#P04395>Signal Peptidase#P04589 MONDO|Ensembl=ENSMODG00000020202.3|UniProtKB=F7G826 F7G826 LOC100028068 PTHR26452:SF263 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10V1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000016797.3|UniProtKB=F7FVU8 F7FVU8 PTHR12801:SF78 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED INTERFERON-STIMULATED 20 KDA EXONUCLEASE-LIKE 2 catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;exoribonuclease#PC00099 MONDO|Ensembl=ENSMODG00000013812.4|UniProtKB=F6SXD4 F6SXD4 PTHR24367:SF268 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH REPEAT LGI FAMILY MEMBER 4 neuron differentiation#GO:0030182;developmental process#GO:0032502;myelination#GO:0042552;neurogenesis#GO:0022008;gliogenesis#GO:0042063;cellular developmental process#GO:0048869;cell maturation#GO:0048469;multicellular organism development#GO:0007275;cellular process#GO:0009987;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;developmental maturation#GO:0021700;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;anatomical structure maturation#GO:0071695;peripheral nervous system development#GO:0007422;cell development#GO:0048468;cell differentiation#GO:0030154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000018992.3|UniProtKB=A0A5F8HKB8 A0A5F8HKB8 HNRNPK PTHR10288:SF356 KH DOMAIN CONTAINING RNA BINDING PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000022966.3|UniProtKB=F6ZJF8 F6ZJF8 NDUFAF3 PTHR21192:SF2 NUCLEAR PROTEIN E3-3 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3 cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000009948.1|UniProtKB=F6QMU8 F6QMU8 C1QL3 PTHR22923:SF96 CEREBELLIN-RELATED COMPLEMENT C1Q-LIKE PROTEIN 3 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000025180.1|UniProtKB=F7FXB8 F7FXB8 LOC100016464 PTHR11599:SF6 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-2 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;proteasome complex#GO:0000502;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368 protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000007209.2|UniProtKB=F6WTC2 F6WTC2 KCNE3 PTHR15282:SF6 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 3 transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;potassium channel regulator activity#GO:0015459;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;voltage-gated channel activity#GO:0022832;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;channel activity#GO:0015267;channel regulator activity#GO:0016247;potassium ion transmembrane transporter activity#GO:0015079 export from cell#GO:0140352;regulation of biological process#GO:0050789;muscle system process#GO:0003012;action potential#GO:0001508;heart process#GO:0003015;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transmembrane transport#GO:0098655;regulation of multicellular organismal process#GO:0051239;cardiac muscle cell action potential involved in contraction#GO:0086002;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;striated muscle contraction#GO:0006941;metal ion transport#GO:0030001;regulation of heart contraction#GO:0008016;actin-mediated cell contraction#GO:0070252;monoatomic cation transport#GO:0006812;localization#GO:0051179;cardiac muscle contraction#GO:0060048;actin filament-based process#GO:0030029;circulatory system process#GO:0003013;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;blood circulation#GO:0008015;potassium ion transport#GO:0006813;multicellular organismal process#GO:0032501;actin filament-based movement#GO:0030048;heart contraction#GO:0060047;system process#GO:0003008;cardiac muscle cell contraction#GO:0086003;establishment of localization#GO:0051234;muscle contraction#GO:0006936;transport#GO:0006810;regulation of system process#GO:0044057 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000018158.3|UniProtKB=F7CD18 F7CD18 USF3 PTHR46970:SF1 BASIC HELIX-LOOP-HELIX DOMAIN-CONTAINING PROTEIN USF3 BASIC HELIX-LOOP-HELIX DOMAIN-CONTAINING PROTEIN USF3 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000046214.1|UniProtKB=A0A5F8H7Q7 A0A5F8H7Q7 NDUFS7 PTHR11995:SF14 NADH DEHYDROGENASE NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;NADH dehydrogenase activity#GO:0003954;oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;monoatomic ion transport#GO:0006811;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;establishment of localization#GO:0051234;cellular respiration#GO:0045333;transmembrane transport#GO:0055085;localization#GO:0051179;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812 membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidoreductase#PC00176;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000012219.4|UniProtKB=F7CE04 F7CE04 VPS33A PTHR11679:SF85 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33A establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;lytic vacuole#GO:0000323 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000000905.4|UniProtKB=F7A6R6 F7A6R6 SLC6A19 PTHR11616:SF125 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT1 neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;brush border#GO:0005903;cellular anatomical structure#GO:0110165;brush border membrane#GO:0031526;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;apical part of cell#GO:0045177;cell projection membrane#GO:0031253;cluster of actin-based cell projections#GO:0098862 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 MONDO|Ensembl=ENSMODG00000043384.1|UniProtKB=A0A5F8H6D0 A0A5F8H6D0 PTHR47634:SF6 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED SRSF PROTEIN KINASE 2 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;signaling#GO:0023052;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;signal transduction#GO:0007165;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000025065.2|UniProtKB=F6SA37 F6SA37 ABHD13 PTHR12277:SF207 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD13 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000042209.1|UniProtKB=A0A5F8GBD1 A0A5F8GBD1 LOC100617160 PTHR23226:SF353 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008173.4|UniProtKB=F7E5C1 F7E5C1 METAP2 PTHR45777:SF2 METHIONINE AMINOPEPTIDASE 2 METHIONINE AMINOPEPTIDASE 2 aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000013593.4|UniProtKB=A0A5F8GFN9 A0A5F8GFN9 PTHR10872:SF4 SH2B ADAPTER PROTEIN SH2B ADAPTER PROTEIN 2 receptor tyrosine kinase binding#GO:0030971;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;enzyme binding#GO:0019899;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674 positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;B cell receptor signaling pathway#GO:0050853;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;immune system process#GO:0002376;regulation of immune response#GO:0050776;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000009429.4|UniProtKB=F7BKT5 F7BKT5 SUN3 PTHR12911:SF24 SAD1/UNC-84-LIKE PROTEIN-RELATED SUN DOMAIN-CONTAINING PROTEIN 3 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;nucleus#GO:0005634;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000023146.3|UniProtKB=F6YVT7 F6YVT7 PTHR24377:SF885 IP01015P-RELATED ZINC FINGER PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008061.4|UniProtKB=F6Z9G0 F6Z9G0 GPR137B PTHR15146:SF0 INTEGRAL MEMBRANE PROTEIN GPR137 INTEGRAL MEMBRANE PROTEIN GPR137B positive regulation of intracellular signal transduction#GO:1902533;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of bone remodeling#GO:0046850;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of TOR signaling#GO:0032008;regulation of tissue remodeling#GO:0034103;regulation of hemopoiesis#GO:1903706;negative regulation of multicellular organismal process#GO:0051241;positive regulation of signal transduction#GO:0009967;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;regulation of multicellular organismal process#GO:0051239;regulation of bone resorption#GO:0045124;regulation of signaling#GO:0023051;regulation of myeloid cell differentiation#GO:0045637;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519 lysosomal membrane#GO:0005765;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000016138.4|UniProtKB=F7D7I0 F7D7I0 KDM1A PTHR10742:SF423 FLAVIN MONOAMINE OXIDASE LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A protein demethylase activity#GO:0140457;heterocyclic compound binding#GO:1901363;demethylase activity#GO:0032451;histone demethylase activity#GO:0032452;histone modifying activity#GO:0140993;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;nucleotide binding#GO:0000166;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;chromatin binding#GO:0003682;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular process#GO:0009987;regulation of biological process#GO:0050789;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 oxidase#PC00175 MONDO|Ensembl=ENSMODG00000009589.4|UniProtKB=F7A9G3 F7A9G3 CCDC172 PTHR22419:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 172 COILED-COIL DOMAIN-CONTAINING PROTEIN 172 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000040468.1|UniProtKB=A0A5F8G937 A0A5F8G937 PTHR24372:SF70 GLYCOPROTEIN HORMONE RECEPTOR RELAXIN FAMILY PEPTIDE RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000017329.4|UniProtKB=F6WWD7 F6WWD7 EDF1 PTHR10245:SF15 ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 MULTIPROTEIN BRIDGING FACTOR 1 ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891 MONDO|Ensembl=ENSMODG00000017160.4|UniProtKB=F6QDP5 F6QDP5 ADAR PTHR10910:SF107 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN DOUBLE-STRANDED RNA-SPECIFIC ADENOSINE DEAMINASE catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity, acting on RNA#GO:0140098;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;tRNA-specific adenosine deaminase activity#GO:0008251;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on a tRNA#GO:0140101;adenosine deaminase activity#GO:0004000;hydrolase activity#GO:0016787;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;base conversion or substitution editing#GO:0016553;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;adenosine to inosine editing#GO:0006382;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000010585.4|UniProtKB=F7GHS2 F7GHS2 FCHSD1 PTHR15735:SF4 FCH AND DOUBLE SH3 DOMAINS PROTEIN F-BAR AND DOUBLE SH3 DOMAINS PROTEIN 1 phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 regulation of protein-containing complex assembly#GO:0043254;chemical synaptic transmission#GO:0007268;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;regulation of actin filament length#GO:0030832;cell communication#GO:0007154;regulation of biological quality#GO:0065008;synaptic signaling#GO:0099536;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament-based process#GO:0032970;neuromuscular synaptic transmission#GO:0007274;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;recycling endosome#GO:0055037;neuromuscular junction#GO:0031594;cell junction#GO:0030054;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000015435.4|UniProtKB=F6SLS5 F6SLS5 LTBP1 PTHR24034:SF140 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 1 binding#GO:0005488;extracellular matrix binding#GO:0050840 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000037675.1|UniProtKB=A0A5F8GHT3 A0A5F8GHT3 PTHR11771:SF216 LIPOXYGENASE ARACHIDONATE 12-LIPOXYGENASE, 12S-TYPE-LIKE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 icosanoid metabolic process#GO:0006690;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid modification#GO:0030258;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;arachidonate metabolic process#GO:0019369;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000000821.4|UniProtKB=F6S9B4 F6S9B4 EIF3D PTHR12399:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 7 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT D translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000007694.4|UniProtKB=A0A5F8G7S2 A0A5F8G7S2 CERS6 PTHR12560:SF43 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 6 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 ceramide metabolic process#GO:0006672;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000013692.4|UniProtKB=F6QP52 F6QP52 BACE1 PTHR47965:SF69 ASPARTYL PROTEASE-RELATED BETA-SECRETASE 1 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;membrane protein proteolysis#GO:0033619;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;membrane protein ectodomain proteolysis#GO:0006509 Golgi apparatus#GO:0005794;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>Pro-BACE-1#P00081;Alzheimer disease-presenilin pathway#P00004>Pro-BACE-1#P00162;Alzheimer disease-amyloid secretase pathway#P00003>BACE-1#P00101;Alzheimer disease-amyloid secretase pathway#P00003>BACE-1 pro-domain#P00094;Alzheimer disease-presenilin pathway#P00004>BACE-1#P00172;Alzheimer disease-presenilin pathway#P00004>BACE-1 pro-domain#P00178 MONDO|Ensembl=ENSMODG00000049062.1|UniProtKB=A0A5F8GAL5 A0A5F8GAL5 PTHR17271:SF10 PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN TRIO AND F-ACTIN-BINDING PROTEIN binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of cell-substrate adhesion#GO:0010811;positive regulation of cell adhesion#GO:0045785;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000016021.3|UniProtKB=F7EG31 F7EG31 PTHR20835:SF0 E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED E3 UBIQUITIN-PROTEIN LIGASE PPP1R11 phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase binding#GO:0019903 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000001669.4|UniProtKB=K7E547 K7E547 SPAG4 PTHR12911:SF16 SAD1/UNC-84-LIKE PROTEIN-RELATED SPERM-ASSOCIATED ANTIGEN 4 PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane#GO:0016020;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000010399.4|UniProtKB=F7A7C5 F7A7C5 RBM20 PTHR15592:SF11 MATRIN 3/NUCLEAR PROTEIN 220-RELATED RNA-BINDING PROTEIN 20 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000000672.4|UniProtKB=F6X212 F6X212 DCLRE1B PTHR23240:SF26 DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED 5' EXONUCLEASE APOLLO catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity#GO:0004529;damaged DNA binding#GO:0003684;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;binding#GO:0005488;nucleic acid binding#GO:0003676;hydrolase activity#GO:0016787;DNA binding#GO:0003677;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;5'-3' exonuclease activity#GO:0008409 response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;double-strand break repair via nonhomologous end joining#GO:0006303;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;double-strand break repair#GO:0006302;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;telomere organization#GO:0032200 intracellular membraneless organelle#GO:0043232;chromosome, telomeric region#GO:0000781;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000004657.4|UniProtKB=F6U7G6 F6U7G6 ST3GAL4 PTHR13713:SF57 SIALYLTRANSFERASE CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 4 glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000028868.2|UniProtKB=K7E0W1 K7E0W1 PTHR10500:SF8 BETA-MICROSEMINOPROTEIN BETA-MICROSEMINOPROTEIN intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000028149.2|UniProtKB=K7E2T0 K7E2T0 PTHR10751:SF117 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 6 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 heterotrimeric G-protein#PC00117;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000028278.2|UniProtKB=A0A5F8H5D0 A0A5F8H5D0 CD99L2 PTHR15076:SF12 CD99/MIC2 PROTEIN RELATED CD99 ANTIGEN-LIKE PROTEIN 2 MONDO|Ensembl=ENSMODG00000023992.2|UniProtKB=F7DPU8 F7DPU8 LOC100617162 PTHR26450:SF177 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52I1-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037387.1|UniProtKB=A0A5F8GJ90 A0A5F8GJ90 VN2R599 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017415.3|UniProtKB=F7AJD6 F7AJD6 PTHR22850:SF90 WD40 REPEAT FAMILY HISTONE-BINDING PROTEIN RBBP4 histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338 transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;histone deacetylase complex#GO:0000118;PcG protein complex#GO:0031519;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000004589.3|UniProtKB=F6QJE2 F6QJE2 LRSAM1 PTHR16083:SF39 LEUCINE RICH REPEAT CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE LRSAM1 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000028134.2|UniProtKB=K7E051 K7E051 PTHR24390:SF230 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 362 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005000.4|UniProtKB=F7F731 F7F731 HK3 PTHR19443:SF1 HEXOKINASE HEXOKINASE-3 hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200 carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;pyruvate metabolic process#GO:0006090;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine nucleoside diphosphate catabolic process#GO:0009137;glucose homeostasis#GO:0042593;nucleobase-containing small molecule metabolic process#GO:0055086;ADP catabolic process#GO:0046032;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;nucleoside phosphate catabolic process#GO:1901292;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine nucleoside triphosphate metabolic process#GO:0009144;ADP metabolic process#GO:0046031;cellular homeostasis#GO:0019725;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;intracellular glucose homeostasis#GO:0001678;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;carbohydrate homeostasis#GO:0033500;ribonucleoside diphosphate metabolic process#GO:0009185;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;catabolic process#GO:0009056;glucose 6-phosphate metabolic process#GO:0051156;nucleoside phosphate metabolic process#GO:0006753;homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;energy derivation by oxidation of organic compounds#GO:0015980;intracellular chemical homeostasis#GO:0055082;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135 outer membrane#GO:0019867;intracellular organelle#GO:0043229;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic side of membrane#GO:0098562;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cytosol#GO:0005829;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 MONDO|Ensembl=ENSMODG00000017020.3|UniProtKB=A0A5F8GMQ8 A0A5F8GMQ8 ZBTB46 PTHR24394:SF29 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 46 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000003992.4|UniProtKB=F7DSD1 F7DSD1 SUGP2 PTHR23340:SF2 ARGININE/SERINE RICH SPLICING FACTOR SF4/14 SURP AND G-PATCH DOMAIN-CONTAINING PROTEIN 2 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000009950.4|UniProtKB=H9H6C8 H9H6C8 CACNB3 PTHR11824:SF8 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-3 voltage-gated ion channel#PC00241 5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587 MONDO|Ensembl=ENSMODG00000027611.2|UniProtKB=K7E4Q5 K7E4Q5 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000046796.1|UniProtKB=A0A5F8HLF1 A0A5F8HLF1 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000005365.3|UniProtKB=A0A5F8H3D0 A0A5F8H3D0 PTHR24369:SF157 ANTIGEN BSP, PUTATIVE-RELATED LRRCT DOMAIN-CONTAINING PROTEIN cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000011579.5|UniProtKB=F6XWP3 F6XWP3 DNAH1 PTHR10676:SF402 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 1 isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;microtubule motor activity#GO:0003777;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488 flagellated sperm motility#GO:0030317;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;cilium movement involved in cell motility#GO:0060294;sperm motility#GO:0097722;cellular process#GO:0009987;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;dynein complex#GO:0030286;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;9+2 motile cilium#GO:0097729;intracellular membraneless organelle#GO:0043232;sperm flagellum#GO:0036126;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000018526.4|UniProtKB=A0A5F8G511 A0A5F8G511 PCCB PTHR43842:SF2 PROPIONYL-COA CARBOXYLASE BETA CHAIN PROPIONYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;ligase#PC00142 Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163;Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033 MONDO|Ensembl=ENSMODG00000006750.4|UniProtKB=F7CCR6 F7CCR6 PPP1R3C PTHR12307:SF15 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3C enzyme binding#GO:0019899;binding#GO:0005488;polysaccharide binding#GO:0030247;phosphatase binding#GO:0019902;protein phosphatase binding#GO:0019903;protein binding#GO:0005515;carbohydrate binding#GO:0030246 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of polysaccharide metabolic process#GO:0032881;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of carbohydrate metabolic process#GO:0006109;regulation of glycogen biosynthetic process#GO:0005979 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000019903.4|UniProtKB=F7DJP0 F7DJP0 PACSIN3 PTHR23065:SF18 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 3 lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 regulation of endocytosis#GO:0030100;cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;membrane organization#GO:0061024 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000016276.5|UniProtKB=A0A5F8G1Q3 A0A5F8G1Q3 STAU1 PTHR46054:SF2 MATERNAL EFFECT PROTEIN STAUFEN DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725 intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;protein localization to synapse#GO:0035418;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;developmental process#GO:0032502;transport#GO:0006810;intracellular transport#GO:0046907;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;axo-dendritic transport#GO:0008088;multicellular organismal reproductive process#GO:0048609;localization#GO:0051179;cellular localization#GO:0051641;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;microtubule-based transport#GO:0099111;protein localization to cell junction#GO:1902414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;reproductive process#GO:0022414;cell differentiation#GO:0030154;RNA localization#GO:0006403;microtubule-based movement#GO:0007018;gamete generation#GO:0007276;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006 membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cell body#GO:0044297 MONDO|Ensembl=ENSMODG00000044404.1|UniProtKB=A0A5F8GJM8 A0A5F8GJM8 WBP1L PTHR16209:SF4 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 WW DOMAIN BINDING PROTEIN 1-LIKE cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemokine#GO:1990868;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;G protein-coupled receptor signaling pathway#GO:0007186;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to chemokine#GO:1990869;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 MONDO|Ensembl=ENSMODG00000013989.6|UniProtKB=A0A5F8GN42 A0A5F8GN42 SLC13A4 PTHR10283:SF63 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000023509.3|UniProtKB=F7DES8 F7DES8 PTHR24393:SF100 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 345-RELATED sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000013148.4|UniProtKB=F7ACJ0 F7ACJ0 PTHR44566:SF1 TRANSDUCIN/WD40 REPEAT-LIKE SUPERFAMILY PROTEIN WD REPEAT-CONTAINING PROTEIN 25 MONDO|Ensembl=ENSMODG00000008498.4|UniProtKB=F7FTS0 F7FTS0 FAM20C PTHR12450:SF11 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 EXTRACELLULAR SERINE_THREONINE PROTEIN KINASE FAM20C catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 developmental process#GO:0032502;biomineral tissue development#GO:0031214;enamel mineralization#GO:0070166;animal gross anatomical part developmental process#GO:0160108;anatomical structure formation involved in morphogenesis#GO:0048646;anatomical structure development#GO:0048856;animal organ development#GO:0048513;anatomical structure morphogenesis#GO:0009653;amelogenesis#GO:0097186;odontogenesis#GO:0042476;odontogenesis of dentin-containing tooth#GO:0042475;tissue development#GO:0009888;animal organ morphogenesis#GO:0009887 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000019152.3|UniProtKB=F7BK66 F7BK66 CCT6B PTHR11353:SF21 CHAPERONIN CHAPERONIN CONTAINING TCP1 SUBUNIT 6A-RELATED metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604 protein folding chaperone complex#GO:0101031;chaperonin-containing T-complex#GO:0005832;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 chaperonin#PC00073 MONDO|Ensembl=ENSMODG00000025766.3|UniProtKB=F7G3B9 F7G3B9 PTHR11905:SF158 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 18 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 cell-cell recognition#GO:0009988;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;animal organ development#GO:0048513;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;male sex differentiation#GO:0046661;development of primary male sexual characteristics#GO:0046546;metabolic process#GO:0008152;sperm-egg recognition#GO:0035036;gonad development#GO:0008406;multicellular organismal process#GO:0032501;male gonad development#GO:0008584;cellular process#GO:0009987;sex differentiation#GO:0007548;single fertilization#GO:0007338;system development#GO:0048731;reproductive system development#GO:0061458;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;binding of sperm to zona pellucida#GO:0007339;sexual reproduction#GO:0019953;cell adhesion#GO:0007155;cell recognition#GO:0008037;proteolysis#GO:0006508;animal gross anatomical part developmental process#GO:0160108;reproductive structure development#GO:0048608;reproductive process#GO:0022414;fertilization#GO:0009566;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000004901.3|UniProtKB=A0A5F8G890 A0A5F8G890 AAMDC PTHR15811:SF5 MTH938 DOMAIN-CONTAINING PROTEIN MTH938 DOMAIN-CONTAINING PROTEIN positive regulation of developmental process#GO:0051094;positive regulation of fat cell differentiation#GO:0045600;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000011816.2|UniProtKB=F6YD14 F6YD14 SPATA24 PTHR35155:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 24 SPERMATOGENESIS-ASSOCIATED PROTEIN 24 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000011821.4|UniProtKB=F6YCI3 F6YCI3 SOS2 PTHR23113:SF150 GUANINE NUCLEOTIDE EXCHANGE FACTOR SON OF SEVENLESS HOMOLOG 2 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 T cell activation#P00053>SOS#P01307;FGF signaling pathway#P00021>SOS#P00641;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>SOS#P00883;PI3 kinase pathway#P00048>SOS#P01185;Interleukin signaling pathway#P00036>SOS#P00981;Ras Pathway#P04393>SOS#P04552;Gonadotropin-releasing hormone receptor pathway#P06664>Sos#P06849;EGF receptor signaling pathway#P00018>SOS#P00558;PDGF signaling pathway#P00047>SOS#P01159;Angiogenesis#P00005>SOS-1#P00193;B cell activation#P00010>SOS#P00379;Integrin signalling pathway#P00034>SOS#P00920 MONDO|Ensembl=ENSMODG00000017531.4|UniProtKB=A0A5F8HFI7 A0A5F8HFI7 KCNT1 PTHR10027:SF14 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN POTASSIUM CHANNEL SUBFAMILY T MEMBER 1 monoatomic ion-gated channel activity#GO:0022839;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transport#GO:0006813 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000016020.4|UniProtKB=F7EFY2 F7EFY2 PTHR12308:SF22 ANOCTAMIN ANOCTAMIN-7 molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 lipid localization#GO:0010876;plasma membrane organization#GO:0007009;localization#GO:0051179;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;membrane organization#GO:0061024;phospholipid transport#GO:0015914;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;endomembrane system organization#GO:0010256 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000016392.4|UniProtKB=F7E919 F7E919 ZNF217 PTHR45925:SF4 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 217 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000023321.2|UniProtKB=F6Y6T7 F6Y6T7 TMEM200A PTHR31815:SF0 AGAP005329-PA TRANSMEMBRANE PROTEIN 200A MONDO|Ensembl=ENSMODG00000045391.1|UniProtKB=A0A5F8GQE1 A0A5F8GQE1 PTHR11437:SF69 RIBONUCLEASE RIBONUCLEASE A-DOMAIN DOMAIN-CONTAINING PROTEIN nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707 RNA metabolism protein#PC00031;endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000045062.1|UniProtKB=A0A5F8HJ19 A0A5F8HJ19 FBP1 PTHR11556:SF11 FRUCTOSE-1,6-BISPHOSPHATASE-RELATED FRUCTOSE-1,6-BISPHOSPHATASE 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;sugar-phosphatase activity#GO:0050308;catalytic activity#GO:0003824 carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;glucose metabolic process#GO:0006006;small molecule biosynthetic process#GO:0044283;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 phosphatase#PC00181;carbohydrate phosphatase#PC00066;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000018735.4|UniProtKB=A0A5F8GKB6 A0A5F8GKB6 PLA2G6 PTHR24139:SF34 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 85_88 KDA CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 glycerophospholipase activity#GO:0004620;deacylase activity#GO:0160215;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;A2-type glycerophospholipase activity#GO:0004623;acyl-CoA hydrolase activity#GO:0016289;lipase activity#GO:0016298;fatty acyl-CoA hydrolase activity#GO:0047617;carboxylic ester hydrolase activity#GO:0052689;thiolester hydrolase activity#GO:0016790;hydrolase activity#GO:0016787 regulation of biosynthetic process#GO:0009889;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;regulation of lipid biosynthetic process#GO:0046890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of lipid metabolic process#GO:0019216;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;glycerolipid metabolic process#GO:0046486;phosphatidylglycerol metabolic process#GO:0046471;regulation of cellular component biogenesis#GO:0044087;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 lipase#PC00143;phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738 MONDO|Ensembl=ENSMODG00000003324.4|UniProtKB=F7DDM9 F7DDM9 PTHR10782:SF12 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS2 ubiquitin-like protein ligase activity#GO:0061659;molecular function inhibitor activity#GO:0140678;acyltransferase activity#GO:0016746;SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein sumoylation#GO:0016925;metabolic process#GO:0008152;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;protein modification by small protein conjugation or removal#GO:0070647;regulation of signaling#GO:0023051;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of biological process#GO:0048519;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;post-translational protein modification#GO:0043687;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;macromolecule modification#GO:0043412;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;protein modification process#GO:0036211 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958;JAK/STAT signaling pathway#P00038>PIAS#P01031 MONDO|Ensembl=ENSMODG00000001838.4|UniProtKB=A0A5F8GZF3 A0A5F8GZF3 ARHGEF28 PTHR13944:SF22 AGAP007712-PA RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 28 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;response to stimulus#GO:0050896 CCKR signaling map#P06959>p190RhoGEF#P07157 MONDO|Ensembl=ENSMODG00000044282.1|UniProtKB=A0A5F8GTQ8 A0A5F8GTQ8 LOC100616696 PTHR24404:SF96 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000001837.4|UniProtKB=F6SPR9 F6SPR9 BCKDK PTHR11947:SF20 PYRUVATE DEHYDROGENASE KINASE BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of lipid metabolic process#GO:0019216;regulation of carbohydrate metabolic process#GO:0006109;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000003845.4|UniProtKB=F7E6D1 F7E6D1 PTHR31854:SF2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 2 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000003635.4|UniProtKB=A0A5F8HJQ1 A0A5F8HJQ1 TXNDC8 PTHR10438:SF230 THIOREDOXIN THIOREDOXIN DOMAIN-CONTAINING PROTEIN 8 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;multicellular organismal reproductive process#GO:0048609;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;developmental process#GO:0032502;homeostatic process#GO:0042592;reproductive process#GO:0022414;gamete generation#GO:0007276;male gamete generation#GO:0048232;developmental process involved in reproduction#GO:0003006 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000012209.4|UniProtKB=F7CE47 F7CE47 LRP3 PTHR24270:SF22 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 3 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 apolipoprotein#PC00052;transfer/carrier protein#PC00219 Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112;Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP#P00150 MONDO|Ensembl=ENSMODG00000014392.4|UniProtKB=F6SRL5 F6SRL5 FCSK PTHR32463:SF0 L-FUCOSE KINASE L-FUCOSE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-sugar metabolic process#GO:0009225;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407 kinase#PC00137;transferase#PC00220 MONDO|Ensembl=ENSMODG00000017889.4|UniProtKB=F7FGR4 F7FGR4 SNAP23 PTHR19305:SF4 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 23 binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484;protein binding#GO:0005515 signal release#GO:0023061;trans-synaptic signaling#GO:0099537;synaptic vesicle fusion to presynaptic active zone membrane#GO:0031629;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;anterograde trans-synaptic signaling#GO:0098916;vesicle fusion#GO:0006906;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;membrane fusion#GO:0061025;synaptic vesicle membrane organization#GO:0048499;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;neurotransmitter secretion#GO:0007269;cellular localization#GO:0051641;secretion by cell#GO:0032940;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;export from cell#GO:0140352;signaling#GO:0023052;regulated exocytosis#GO:0045055;vesicle fusion to plasma membrane#GO:0099500;exocytic process#GO:0140029;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174 intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;protein-containing complex#GO:0032991 SNARE protein#PC00034;membrane traffic protein#PC00150 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423 MONDO|Ensembl=ENSMODG00000008119.4|UniProtKB=F7FV41 F7FV41 NID1 PTHR46513:SF6 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED NIDOGEN-1 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010976.4|UniProtKB=A0A5F8GXA9 A0A5F8GXA9 MTHFR PTHR45754:SF3 METHYLENETETRAHYDROFOLATE REDUCTASE METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH) oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 sulfur compound metabolic process#GO:0006790;aspartate family amino acid biosynthetic process#GO:0009067;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;oxoacid metabolic process#GO:0043436;tetrahydrofolate biosynthetic process#GO:0046654;tetrahydrofolate metabolic process#GO:0046653 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 reductase#PC00198 MONDO|Ensembl=ENSMODG00000047092.1|UniProtKB=A0A5F8HIB4 A0A5F8HIB4 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000004872.4|UniProtKB=A0A5F8H5Z6 A0A5F8H5Z6 CCDC18 PTHR18875:SF8 SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO COILED-COIL DOMAIN-CONTAINING PROTEIN 18 microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriolar satellite#GO:0034451;intracellular membraneless organelle#GO:0043232 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000018699.4|UniProtKB=A0A5F8H6A0 A0A5F8H6A0 PHF3 PTHR11477:SF10 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN PHD FINGER PROTEIN 3 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000045403.1|UniProtKB=A0A5F8H893 A0A5F8H893 ATP6V0E2 PTHR12263:SF2 VACUOLAR ATP SYNTHASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT E 2 proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810 cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;proton-transporting two-sector ATPase complex#GO:0016469;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;vacuolar membrane#GO:0005774 ATP synthase#PC00002;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000003273.4|UniProtKB=F6XNN0 F6XNN0 DNMBP PTHR22834:SF19 NUCLEAR FUSION PROTEIN FUS2 DYNAMIN-BINDING PROTEIN molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;guanyl-nucleotide exchange factor activity#GO:0005085 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000017371.5|UniProtKB=A0A5F8HL37 A0A5F8HL37 ARHGAP6 PTHR12635:SF7 RHO-GTPASE-ACTIVATING PROTEIN 6 FAMILY MEMBER RHO GTPASE ACTIVATING PROTEIN 36-RELATED molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 PDGF signaling pathway#P00047>Rho#P01174 MONDO|Ensembl=ENSMODG00000005522.4|UniProtKB=F7G587 F7G587 THAP11 PTHR22794:SF2 THAP DOMAIN PROTEIN 11 THAP DOMAIN-CONTAINING PROTEIN 11 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000001835.1|UniProtKB=F6SPU8 F6SPU8 LOC100032028 PTHR31423:SF3 YBAK DOMAIN-CONTAINING PROTEIN PROLYL-TRNA SYNTHETASE ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED MONDO|Ensembl=ENSMODG00000024609.1|UniProtKB=F7C2G9 F7C2G9 LOC100013658 PTHR26453:SF58 OLFACTORY RECEPTOR OLFACTORY RECEPTOR FAMILY 13 SUBFAMILY P MEMBER 9 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019871.3|UniProtKB=A0A5F8HHJ7 A0A5F8HHJ7 TSPAN18 PTHR19282:SF249 TETRASPANIN TETRASPANIN-18 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000027935.2|UniProtKB=A0A5F8GUL8 A0A5F8GUL8 EMCN PTHR15869:SF0 ENDOMUCIN-RELATED ENDOMUCIN negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell adhesion#GO:0007162;negative regulation of cell-cell adhesion#GO:0022408;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;negative regulation of leukocyte cell-cell adhesion#GO:1903038;biological regulation#GO:0065007;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 MONDO|Ensembl=ENSMODG00000037252.1|UniProtKB=A0A5F8HJS5 A0A5F8HJS5 PFDN1 PTHR20903:SF0 PREFOLDIN SUBUNIT 1-RELATED PREFOLDIN SUBUNIT 1 protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000046995.1|UniProtKB=A0A5F8HJ88 A0A5F8HJ88 FGF7 PTHR11486:SF20 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 7 receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;fibroblast growth factor receptor binding#GO:0005104;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515 regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;system development#GO:0048731;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;positive regulation of epithelial cell proliferation#GO:0050679;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of cell migration#GO:0030334;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of cellular process#GO:0048522;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;tube development#GO:0035295;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 extracellular region#GO:0005576;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 Fructose galactose metabolism#P02744>Galactokinase#P02960;FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000015551.4|UniProtKB=F6SK59 F6SK59 PUS1 PTHR11142:SF4 PSEUDOURIDYLATE SYNTHASE PSEUDOURIDYLATE SYNTHASE 1 HOMOLOG catalytic activity, acting on a tRNA#GO:0140101;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;catalytic activity, acting on a nucleic acid#GO:0140640 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;pseudouridine synthesis#GO:0001522;mRNA modification#GO:0016556;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 lyase#PC00144 MONDO|Ensembl=ENSMODG00000008228.4|UniProtKB=F6ZY60 F6ZY60 BHLHE22 PTHR19290:SF52 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 22 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;axon development#GO:0061564;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;sensory organ development#GO:0007423;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000037740.1|UniProtKB=A0A5F8G6X3 A0A5F8G6X3 PTHR23087:SF27 NONHISTONE CHROMOSOMAL PROTEIN HMG DRESDEN PROSTATE CARCINOMA PROTEIN 2-RELATED chromatin binding#GO:0003682;binding#GO:0005488 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000017568.3|UniProtKB=F7BSG6 F7BSG6 ENTR1 PTHR31259:SF3 ENDOSOME-ASSOCIATED TRAFFICKING REGULATOR 1 ENDOSOME-ASSOCIATED-TRAFFICKING REGULATOR 1 regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;recycling endosome#GO:0055037;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;midbody#GO:0030496;intracellular vesicle#GO:0097708;vesicle#GO:0031982 MONDO|Ensembl=ENSMODG00000049482.1|UniProtKB=A0A5F8HGD9 A0A5F8HGD9 PTHR15907:SF32 DUF614 FAMILY PROTEIN-RELATED PLACENTA-SPECIFIC GENE 8 PROTEIN regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219 MONDO|Ensembl=ENSMODG00000018966.2|UniProtKB=F7G048 F7G048 LOC107651142 PTHR19424:SF3 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR-BINDING PROTEIN 1 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;heat acclimation#GO:0010286;response to heat#GO:0009408;cellular response to heat#GO:0034605;response to temperature stimulus#GO:0009266;response to stimulus#GO:0050896;cellular response to stress#GO:0033554 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000038191.1|UniProtKB=A0A5F8GN91 A0A5F8GN91 monDomV1R1255 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005139.3|UniProtKB=F7EQG0 F7EQG0 PLA2G15 PTHR11440:SF47 LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED LYSOSOMAL PHOSPHOLIPASE A AND ACYLTRANSFERASE hydrolase activity#GO:0016787;acyltransferase activity#GO:0016746;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;A2-type glycerophospholipase activity#GO:0004623;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;glycerophospholipase activity#GO:0004620;transferase activity#GO:0016740;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 ceramide metabolic process#GO:0006672;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phosphatidylcholine metabolic process#GO:0046470;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosome#GO:0005764;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 acyltransferase#PC00042;transferase#PC00220 MONDO|Ensembl=ENSMODG00000025474.3|UniProtKB=F6QZQ2 F6QZQ2 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010660.4|UniProtKB=F7CKI2 F7CKI2 PTHR16932:SF25 INTERFERON ALPHA-INDUCIBLE PROTEIN 27 INTERFERON ALPHA-INDUCIBLE PROTEIN 6 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;apoptotic signaling pathway#GO:0097190;intrinsic apoptotic signaling pathway#GO:0097193;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;cell death#GO:0008219;programmed cell death#GO:0012501;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000001296.3|UniProtKB=F7BZZ9 F7BZZ9 PTHR46473:SF6 GH08155P LEUCINE-RICH REPEAT-CONTAINING PROTEIN 52 transmembrane transporter binding#GO:0044325;transporter regulator activity#GO:0141108;potassium channel activity#GO:0005267;channel regulator activity#GO:0016247;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;ion channel regulator activity#GO:0099106;passive transmembrane transporter activity#GO:0022803;molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;voltage-gated potassium channel activity#GO:0005249;potassium channel regulator activity#GO:0015459;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;binding#GO:0005488;molecular function activator activity#GO:0140677;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 MONDO|Ensembl=ENSMODG00000025697.3|UniProtKB=F6TJ39 F6TJ39 PTHR13930:SF0 S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399 lyase#PC00144 MONDO|Ensembl=ENSMODG00000009553.3|UniProtKB=F7BJX5 F7BJX5 SFTPC PTHR10800:SF7 PULMONARY SURFACTANT-ASSOCIATED PROTEIN C SURFACTANT PROTEIN C extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 surfactant#PC00212;structural protein#PC00211 MONDO|Ensembl=ENSMODG00000038095.1|UniProtKB=A0A5F8G696 A0A5F8G696 PTHR23262:SF186 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 1-1 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000048367.1|UniProtKB=A0A5F8G932 A0A5F8G932 PTHR21366:SF14 GLYOXALASE FAMILY PROTEIN GLYOXALASE DOMAIN-CONTAINING PROTEIN 5 MONDO|Ensembl=ENSMODG00000005696.3|UniProtKB=F6UKR9 F6UKR9 DTD1 PTHR10472:SF5 D-TYROSYL-TRNA TYR DEACYLASE D-AMINOACYL-TRNA DEACYLASE 1 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;deacylase activity#GO:0160215;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098 nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;esterase#PC00097;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000023300.1|UniProtKB=F6VBX1 F6VBX1 PTHR17045:SF5 MELANOCYTE SPECIFIC GENE RELATED CITED CBP_P300-INTERACTING TRANSACTIVATOR 4 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to hormone#GO:0009725;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 MONDO|Ensembl=ENSMODG00000018587.3|UniProtKB=F7FD53 F7FD53 SMPD1 PTHR10340:SF34 SPHINGOMYELIN PHOSPHODIESTERASE SPHINGOMYELIN PHOSPHODIESTERASE phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;cellular process#GO:0009987;lipid catabolic process#GO:0016042;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingomyelin metabolic process#GO:0006684;ceramide metabolic process#GO:0006672;organophosphate catabolic process#GO:0046434;phosphorus metabolic process#GO:0006793;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;lysosome#GO:0005764;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 hydrolase#PC00121;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000046652.1|UniProtKB=A0A5F8GQ33 A0A5F8GQ33 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000044492.1|UniProtKB=A0A5F8HM05 A0A5F8HM05 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000039367.1|UniProtKB=A0A5F8G828 A0A5F8G828 YAP1 PTHR17616:SF9 YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER TRANSCRIPTIONAL COACTIVATOR YAP1 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 positive regulation of transcription by RNA polymerase II#GO:0045944;hippo signaling#GO:0035329;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;positive regulation of epithelial cell proliferation#GO:0050679;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000008046.4|UniProtKB=F6ZA19 F6ZA19 CYTH3 PTHR10663:SF320 GUANYL-NUCLEOTIDE EXCHANGE FACTOR CYTOHESIN-3 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000019517.4|UniProtKB=F6VD48 F6VD48 IL6ST PTHR23036:SF83 CYTOKINE RECEPTOR INTERLEUKIN-6 RECEPTOR SUBUNIT BETA cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515 cell surface receptor signaling pathway#GO:0007166;response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Signaling subunit#P00969 MONDO|Ensembl=ENSMODG00000036979.1|UniProtKB=A0A5F8G8I2 A0A5F8G8I2 DDRGK1 PTHR48176:SF4 DDRGK DOMAIN-CONTAINING PROTEIN 1 DDRGK DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899 regulation of biological process#GO:0050789;regulation of response to endoplasmic reticulum stress#GO:1905897;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;system development#GO:0048731;regulation of cellular response to stress#GO:0080135;cartilage development#GO:0051216;negative regulation of cell communication#GO:0010648;skeletal system development#GO:0001501;negative regulation of intracellular signal transduction#GO:1902532;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;tissue development#GO:0009888;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;connective tissue development#GO:0061448;multicellular organism development#GO:0007275;animal organ development#GO:0048513 MONDO|Ensembl=ENSMODG00000006907.4|UniProtKB=F6PTR3 F6PTR3 CASTOR2 PTHR31131:SF2 CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE CYTOSOLIC ARGININE SENSOR FOR MTORC1 SUBUNIT 2 regulation of TORC1 signaling#GO:1903432;negative regulation of cellular process#GO:0048523;negative regulation of TORC1 signaling#GO:1904262;regulation of response to stimulus#GO:0048583;response to chemical#GO:0042221;negative regulation of response to stimulus#GO:0048585;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;response to acid chemical#GO:0001101;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;negative regulation of intracellular signal transduction#GO:1902532;response to nitrogen compound#GO:1901698;negative regulation of cell communication#GO:0010648;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to amino acid stimulus#GO:0071230;negative regulation of TOR signaling#GO:0032007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000007762.4|UniProtKB=F7EQS9 F7EQS9 PTHR16065:SF2 COILED-COIL DOMAIN CONTAINING 198 FACTOR ASSOCIATED WITH METABOLISM AND ENERGY MONDO|Ensembl=ENSMODG00000013505.4|UniProtKB=F7F8B9 F7F8B9 RSPRY1 PTHR13363:SF6 RING FINGER AND SRY DOMAIN-CONTAINING RING FINGER AND SPRY DOMAIN-CONTAINING PROTEIN 1 ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000018180.4|UniProtKB=F7BU08 F7BU08 CASP8AP2 PTHR15489:SF2 CASPASE 8 ASSOCIATED PROTEIN 2 CASP8-ASSOCIATED PROTEIN 2 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cell surface receptor signaling pathway#GO:0007166;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;apoptotic signaling pathway#GO:0097190;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;cell communication#GO:0007154;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;cell death#GO:0008219;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;organelle lumen#GO:0043233;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear body#GO:0016604;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000000974.4|UniProtKB=F7A2Q4 F7A2Q4 UBE3A PTHR45622:SF82 UBIQUITIN-PROTEIN LIGASE E3A-RELATED UBIQUITIN-PROTEIN LIGASE E3A catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of protein catabolic process#GO:0042176;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 MONDO|Ensembl=ENSMODG00000011778.4|UniProtKB=A0A5F8GJD8 A0A5F8GJD8 MAP4K5 PTHR48012:SF19 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 5 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>GCK#P00268;Apoptosis signaling pathway#P00006>GCKR#P00311;Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861 MONDO|Ensembl=ENSMODG00000005438.4|UniProtKB=F7D0K5 F7D0K5 SERPINB11 PTHR11461:SF199 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B11 peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000016191.4|UniProtKB=F7FYE1 F7FYE1 KCNS1 PTHR11537:SF61 VOLTAGE-GATED POTASSIUM CHANNEL DELAYED-RECTIFIER POTASSIUM CHANNEL REGULATORY SUBUNIT KCNS1 potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;action potential#GO:0001508;metal ion transport#GO:0030001 cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000002439.4|UniProtKB=F7DF31 F7DF31 PTHR19964:SF11 MULTIPLE PDZ DOMAIN PROTEIN INAD-LIKE PROTEIN cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell junction organization#GO:0034330 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cytoplasm#GO:0005737;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;apical junction complex#GO:0043296;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;tight junction#GO:0070160 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006656.4|UniProtKB=F7FTQ0 F7FTQ0 MIDEAS PTHR16089:SF24 REST COREPRESSOR COREST PROTEIN-RELATED MITOTIC DEACETYLASE-ASSOCIATED SANT DOMAIN PROTEIN transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000029174.2|UniProtKB=K7E501 K7E501 PTHR48018:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 974 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004860.3|UniProtKB=F6TP16 F6TP16 MKKS PTHR46787:SF1 SYNDROMES PUTATIVE CHAPERONIN-RELATED MOLECULAR CHAPERONE MKKS organelle assembly#GO:0070925;chaperone-mediated protein complex assembly#GO:0051131;cilium organization#GO:0044782;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;neuron projection#GO:0043005;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000029736.2|UniProtKB=K7E203 K7E203 TEX46 PTHR39412:SF1 TESTIS-EXPRESSED PROTEIN 46 TESTIS-EXPRESSED PROTEIN 46 fertilization#GO:0009566;reproductive process#GO:0022414;sexual reproduction#GO:0019953;single fertilization#GO:0007338 MONDO|Ensembl=ENSMODG00000010453.4|UniProtKB=F7F7T0 F7F7T0 GTPBP10 PTHR11702:SF43 DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED GTP-BINDING PROTEIN 10 heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000003670.4|UniProtKB=A0A5F8HLS9 A0A5F8HLS9 CDH18 PTHR24027:SF106 CADHERIN-23 CADHERIN-18 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component assembly#GO:0022607;cell migration#GO:0016477;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;cell junction organization#GO:0034330;cell motility#GO:0048870;cell morphogenesis#GO:0000902;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000005109.4|UniProtKB=F6ZDS8 F6ZDS8 LHFPL1 PTHR12489:SF15 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 1 PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000001568.4|UniProtKB=A0A5F8H746 A0A5F8H746 ITGAL PTHR23220:SF84 INTEGRIN ALPHA INTEGRIN ALPHA-L molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589 integrin complex#GO:0008305;signaling receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797 integrin#PC00126;cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Integrin alpha#P00941;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853 MONDO|Ensembl=ENSMODG00000001241.4|UniProtKB=F7AQN9 F7AQN9 MGAT4A PTHR12062:SF4 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE A hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;Golgi stack#GO:0005795;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 transferase#PC00220 MONDO|Ensembl=ENSMODG00000010522.4|UniProtKB=F7DQL3 F7DQL3 HGH1 PTHR13387:SF9 PROTEIN HGH1 HOMOLOG CO-CHAPERONE PROTEIN HGH1 HOMOLOG MONDO|Ensembl=ENSMODG00000005454.3|UniProtKB=F7CGR9 F7CGR9 UBOX5 PTHR13492:SF2 RING FINGER PROTEIN 37 RING FINGER PROTEIN 37 catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;transferase activity#GO:0016740;ubiquitin protein ligase binding#GO:0031625;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000008643.4|UniProtKB=F6PGG6 F6PGG6 GET4 PTHR12875:SF3 GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein insertion into membrane#GO:0051205;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000024987.1|UniProtKB=F6U9L6 F6U9L6 PEX2 PTHR48178:SF3 PEROXISOME BIOGENESIS FACTOR 2 PEROXISOME BIOGENESIS FACTOR 2 lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;peroxisome organization#GO:0007031;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;very long-chain fatty acid metabolic process#GO:0000038;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;lipid modification#GO:0030258;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;monocarboxylic acid catabolic process#GO:0072329;organelle organization#GO:0006996;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 nuclear protein-containing complex#GO:0140513;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;peroxisomal membrane#GO:0005778;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;microbody#GO:0042579;RNA polymerase complex#GO:0030880;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;organelle lumen#GO:0043233;peroxisome#GO:0005777;nuclear DNA-directed RNA polymerase complex#GO:0055029 MONDO|Ensembl=ENSMODG00000028004.2|UniProtKB=K7E030 K7E030 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000021246.4|UniProtKB=F6TJE3 F6TJE3 PLOD2 PTHR10730:SF6 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE 2 dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;extracellular region#GO:0005576;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000017440.3|UniProtKB=F6ZTY7 F6ZTY7 FAM229A PTHR35355:SF1 PROTEIN FAM229A PROTEIN FAM229A MONDO|Ensembl=ENSMODG00000013204.3|UniProtKB=F7EWH6 F7EWH6 PTHR15953:SF0 APELIN APELIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000008778.3|UniProtKB=F6RG45 F6RG45 LOC100011278 PTHR26451:SF237 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 13G1 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000019497.4|UniProtKB=F6VUW8 F6VUW8 HM13 PTHR12174:SF23 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;cytoplasmic side of membrane#GO:0098562;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;endomembrane system#GO:0012505;membrane#GO:0016020 aspartic protease#PC00053;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000015989.5|UniProtKB=F7EGD9 F7EGD9 TNIK PTHR48015:SF39 SERINE/THREONINE-PROTEIN KINASE TAO TRAF2 AND NCK-INTERACTING PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;intracellular signaling cassette#GO:0141124;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000025314.3|UniProtKB=F7ENK3 F7ENK3 GPR82 PTHR47392:SF1 G-PROTEIN COUPLED RECEPTOR 82-RELATED G PROTEIN-COUPLED RECEPTOR 82-RELATED transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000024321.1|UniProtKB=F7E0L5 F7E0L5 PTHR48018:SF44 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8J1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016356.4|UniProtKB=F6XRX5 F6XRX5 DPM1 PTHR43398:SF1 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030 glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000037529.1|UniProtKB=A0A5F8G4Z1 A0A5F8G4Z1 PTHR24070:SF396 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN R-RAS2 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 establishment or maintenance of cell polarity#GO:0007163;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 EGF receptor signaling pathway#P00018>Ras#P00552;TGF-beta signaling pathway#P00052>Ras-GDP#P01291;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;TGF-beta signaling pathway#P00052>Ras-GTP#P01280 MONDO|Ensembl=ENSMODG00000014061.4|UniProtKB=F6U836 F6U836 PTHR13856:SF31 VHS DOMAIN CONTAINING PROTEIN FAMILY TOM1-LIKE PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;clathrin binding#GO:0030276 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000012186.3|UniProtKB=F7CXY2 F7CXY2 B3GNT4 PTHR11214:SF368 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 aminoglycan biosynthetic process#GO:0006023;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000049079.1|UniProtKB=A0A5F8GFR8 A0A5F8GFR8 PTHR13622:SF14 THIAMIN PYROPHOSPHOKINASE THIAMINE PYROPHOSPHOKINASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;alcohol biosynthetic process#GO:0046165;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 transferase#PC00220;kinase#PC00137 Thiamin metabolism#P02780>Thiamine kinase#P03176 MONDO|Ensembl=ENSMODG00000015648.3|UniProtKB=A0A5F8GPZ7 A0A5F8GPZ7 TMEM132C PTHR13388:SF4 DETONATOR, ISOFORM E TRANSMEMBRANE PROTEIN 132C membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000004869.3|UniProtKB=F6TN79 F6TN79 CCNJ PTHR10177:SF62 CYCLINS CYCLIN-J cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887 cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047 intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;transferase complex#GO:1990234;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000021006.2|UniProtKB=F6Z9T0 F6Z9T0 CLDN14 PTHR12002:SF99 CLAUDIN CLAUDIN-14 cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216 bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;apical junction complex#GO:0043296 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000006071.4|UniProtKB=F7FF03 F7FF03 PGF PTHR12025:SF9 VASCULAR ENDOTHELIAL GROWTH FACTOR PLACENTA GROWTH FACTOR molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083 regulation of response to external stimulus#GO:0032101;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of response to external stimulus#GO:0032103;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;signaling#GO:0023052;response to abiotic stimulus#GO:0009628;blood vessel morphogenesis#GO:0048514;response to endogenous stimulus#GO:0009719;positive regulation of cell motility#GO:2000147;regulation of chemotaxis#GO:0050920;vascular endothelial growth factor receptor signaling pathway#GO:0048010;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;sprouting angiogenesis#GO:0002040;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;tube development#GO:0035295;biological regulation#GO:0065007;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;positive regulation of locomotion#GO:0040017;response to hypoxia#GO:0001666;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of leukocyte migration#GO:0002685;response to growth factor#GO:0070848;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of chemotaxis#GO:0050921;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 MONDO|Ensembl=ENSMODG00000038114.1|UniProtKB=A0A5F8GUW0 A0A5F8GUW0 PTHR10206:SF2 CATHELICIDIN CATHELICIDIN ANTIMICROBIAL PEPTIDE lipid binding#GO:0008289;carbohydrate derivative binding#GO:0097367;binding#GO:0005488;lipopolysaccharide binding#GO:0001530 humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to other organism#GO:0051707;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;defense response to Gram-negative bacterium#GO:0050829;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051 MONDO|Ensembl=ENSMODG00000038045.1|UniProtKB=A0A5F8GVG5 A0A5F8GVG5 TMEM262 PTHR37998:SF1 TRANSMEMBRANE PROTEIN 262 CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT ETA MONDO|Ensembl=ENSMODG00000014548.4|UniProtKB=F7E8Y9 F7E8Y9 CPA5 PTHR11705:SF16 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A5 carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000016101.5|UniProtKB=F7EB26 F7EB26 EPHA8 PTHR46877:SF7 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 8 signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;axon development#GO:0061564;axon guidance#GO:0007411;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013238.4|UniProtKB=F7DV65 F7DV65 PTHR14150:SF12 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 UTP14A SMALL SUBUNIT PROCESSOME COMPONENT enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000007025.4|UniProtKB=F6UFV2 F6UFV2 CCNE2 PTHR10177:SF70 CYCLINS G1_S-SPECIFIC CYCLIN-E2 enzyme regulator activity#GO:0030234;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 G1/S transition of mitotic cell cycle#GO:0000082;positive regulation of cell cycle G1/S phase transition#GO:1902808;positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of G1/S transition of mitotic cell cycle#GO:2000045;mitotic cell cycle phase transition#GO:0044772;regulation of mitotic cell cycle phase transition#GO:1901990;cell cycle process#GO:0022402;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;nucleus#GO:0005634 kinase activator#PC00138 Parkinson disease#P00049>Cyclin E#P01213;Cell cycle#P00013>CdkC#P00489 MONDO|Ensembl=ENSMODG00000007082.3|UniProtKB=F6UEL3 F6UEL3 LOC100022712 PTHR26453:SF758 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000022854.2|UniProtKB=F6PJB2 F6PJB2 SPMAP2 PTHR15901:SF16 TESTICULAR HAPLOID EXPRESSED GENE PROTEIN SPERM MICROTUBULE ASSOCIATED PROTEIN 2 multicellular organismal reproductive process#GO:0048609;developmental process#GO:0032502;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;reproductive process#GO:0022414;male gamete generation#GO:0048232;gamete generation#GO:0007276;developmental process involved in reproduction#GO:0003006 MONDO|Ensembl=ENSMODG00000005638.4|UniProtKB=A0A5F8GVC7 A0A5F8GVC7 PTHR24133:SF36 ANKYRIN DOMAIN-CONTAINING ANKYRIN-2 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;cytoskeletal adaptor activity#GO:0008093;cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090 localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;protein localization to plasma membrane#GO:0072659;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006443.3|UniProtKB=F7EGJ1 F7EGJ1 GINS1 PTHR12914:SF2 PARTNER OF SLD5 DNA REPLICATION COMPLEX GINS PROTEIN PSF1 macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;DNA metabolic process#GO:0006259;nuclear DNA replication#GO:0033260;mitotic DNA replication#GO:1902969;cell cycle DNA replication#GO:0044786;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA-templated DNA replication#GO:0006261;mitotic cell cycle#GO:0000278;DNA strand elongation involved in DNA replication#GO:0006271;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;DNA replication#GO:0006260;cell cycle process#GO:0022402 DNA replication preinitiation complex#GO:0031261;organelle lumen#GO:0043233;chromosome#GO:0005694;GINS complex#GO:0000811;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;CMG complex#GO:0071162;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000016284.4|UniProtKB=F7AUL0 F7AUL0 FAM117B PTHR14972:SF6 AGAP011572-PA PROTEIN FAM117B MONDO|Ensembl=ENSMODG00000012283.4|UniProtKB=F6YFV8 F6YFV8 SEMA3F PTHR11036:SF27 SEMAPHORIN SEMAPHORIN-3F binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 locomotion#GO:0040011;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cellular response to stimulus#GO:0051716;system development#GO:0048731;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;chemotaxis#GO:0006935;stem cell development#GO:0048864;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;tissue development#GO:0009888;neural crest cell development#GO:0014032;cell migration#GO:0016477;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon development#GO:0061564;stem cell differentiation#GO:0048863;axon guidance#GO:0007411;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;neurogenesis#GO:0022008;mesenchyme development#GO:0060485;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;taxis#GO:0042330;response to chemical#GO:0042221;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;neural crest cell migration#GO:0001755;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;neuron differentiation#GO:0030182;neural crest cell differentiation#GO:0014033;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;mesenchymal cell differentiation#GO:0048762 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000009988.3|UniProtKB=A0A5F8HDP0 A0A5F8HDP0 KCNJ9 PTHR11767:SF17 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 3 metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724 MONDO|Ensembl=ENSMODG00000000067.4|UniProtKB=A0A5F8GVM3 A0A5F8GVM3 MICU1 PTHR12294:SF1 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 1, MITOCHONDRIAL calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;mitochondrial calcium ion homeostasis#GO:0051560;metal ion transport#GO:0030001;homeostatic process#GO:0042592;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;mitochondrial calcium ion transmembrane transport#GO:0006851;cellular process#GO:0009987 transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;calcium channel complex#GO:0034704;mitochondrion#GO:0005739;transporter complex#GO:1990351;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cation channel complex#GO:0034703;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000025524.3|UniProtKB=A0A5F8GLQ1 A0A5F8GLQ1 PTHR31102:SF1 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 9 MEMBER B2 MONDO|Ensembl=ENSMODG00000050774.1|UniProtKB=A0A5F8G428 A0A5F8G428 NDP PTHR28611:SF1 NORRIN NORRIN binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604 MONDO|Ensembl=ENSMODG00000003993.4|UniProtKB=F7DSA7 F7DSA7 SNX7 PTHR45949:SF3 SORTING NEXIN-4 SORTING NEXIN-7 transport#GO:0006810;autophagy of mitochondrion#GO:0000422;intracellular transport#GO:0046907;metabolic process#GO:0008152;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;mitophagy#GO:0000423;cellular process#GO:0009987;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;reticulophagy#GO:0061709;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;vesicle-mediated transport#GO:0016192;localization within membrane#GO:0051668;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;localization#GO:0051179;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;endocytic recycling#GO:0032456 endosome#GO:0005768;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000015996.4|UniProtKB=F7EZ13 F7EZ13 KANSL3 PTHR13136:SF16 TESTIS DEVELOPMENT PROTEIN PRTD KAT8 REGULATORY NSL COMPLEX SUBUNIT 3 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944 protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;NSL complex#GO:0044545;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;chromatin#GO:0000785;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000024959.2|UniProtKB=F6UCA5 F6UCA5 NPY2R PTHR24235:SF20 NEUROPEPTIDE Y RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 2 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;membrane-bounded organelle#GO:0043227 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000001900.3|UniProtKB=A0A5F8GTP0 A0A5F8GTP0 NSA2 PTHR12642:SF0 RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000004099.5|UniProtKB=F6VF05 F6VF05 MMS19 PTHR12891:SF1 DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19 MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000012691.3|UniProtKB=F6UZ04 F6UZ04 NKX2-1 PTHR24340:SF33 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000002658.4|UniProtKB=F6ZI23 F6ZI23 ABHD17B PTHR12277:SF48 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17B catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096 regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of postsynapse organization#GO:0099175;regulation of synapse structure or activity#GO:0050803;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of synapse organization#GO:0050807 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000008955.4|UniProtKB=F7GCN9 F7GCN9 GTF3A PTHR24388:SF76 ZINC FINGER PROTEIN TRANSCRIPTION FACTOR IIIA transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005376.4|UniProtKB=A0A5F8GWY2 A0A5F8GWY2 AHSA1 PTHR13009:SF7 HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1 ACTIVATOR OF 90 KDA HEAT SHOCK PROTEIN ATPASE HOMOLOG 1 ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000003762.3|UniProtKB=F7AAN3 F7AAN3 SLC22A31 PTHR24064:SF196 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 31-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000008675.2|UniProtKB=F6PFU2 F6PFU2 ZNF395 PTHR13006:SF6 PAPILLOMAVIRUS REGULATORY FACTOR PRF-1 ZINC FINGER PROTEIN 395 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000025057.2|UniProtKB=Q2AB99 Q2AB99 T2R7B PTHR11394:SF58 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 7 molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of taste#GO:0050909;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010527.4|UniProtKB=F6VEX0 F6VEX0 MYO18B PTHR45615:SF8 MYOSIN HEAVY CHAIN, NON-MUSCLE UNCONVENTIONAL MYOSIN-XVIIIB actin binding#GO:0003779;actin filament binding#GO:0051015;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000024275.1|UniProtKB=F6Z5D8 F6Z5D8 LOC100619945 PTHR48018:SF168 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013971.3|UniProtKB=F6R6Y3 F6R6Y3 PTHR23267:SF483 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-25 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000007564.2|UniProtKB=F7FZY8 F7FZY8 LOC100616733 PTHR24242:SF388 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000044147.1|UniProtKB=A0A5F8H266 A0A5F8H266 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000008964.2|UniProtKB=F7G2D0 F7G2D0 EIF1AD PTHR21641:SF0 TRANSLATION INITIATION FACTOR-RELATED RNA-BINDING PROTEIN EIF1AD-RELATED cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 translation initiation factor#PC00224;translation factor#PC00223 MONDO|Ensembl=ENSMODG00000038109.1|UniProtKB=A0A5F8G9G2 A0A5F8G9G2 OST4 PTHR48164:SF1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 4 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 4 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000049071.1|UniProtKB=A0A5F8G6K4 A0A5F8G6K4 KIFBP PTHR46321:SF1 KIF1-BINDING PROTEIN KIF-BINDING PROTEIN neuron projection organization#GO:0106027;cell projection organization#GO:0030030;cell differentiation#GO:0030154;central nervous system development#GO:0007417;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;microtubule-based process#GO:0007017;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;system development#GO:0048731;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;central nervous system neuron differentiation#GO:0021953 MONDO|Ensembl=ENSMODG00000036508.1|UniProtKB=A0A5F8GZN5 A0A5F8GZN5 PTHR23428:SF326 HISTONE H2B HISTONE H2B TYPE 1-J immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;defense response#GO:0006952;response to external stimulus#GO:0009605;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000013800.3|UniProtKB=F6TDD2 F6TDD2 BUD23 PTHR12734:SF0 METHYLTRANSFERASE-RELATED 18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;rRNA (guanine) methyltransferase activity#GO:0016435;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640 gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;rRNA metabolic process#GO:0016072;transport#GO:0006810;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;localization#GO:0051179;nuclear transport#GO:0051169;nuclear export#GO:0051168;rRNA processing#GO:0006364;organelle localization#GO:0051640;ribosome localization#GO:0033750;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000001515.4|UniProtKB=F7F485 F7F485 POU4F1 PTHR11636:SF42 POU DOMAIN POU DOMAIN, CLASS 4, TRANSCRIPTION FACTOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000046047.1|UniProtKB=H9H9G4 H9H9G4 PTHR24381:SF479 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 432 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002501.4|UniProtKB=A0A5F8GFU0 A0A5F8GFU0 ALDH1A1 PTHR11699:SF140 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE 1A1 oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity#GO:0016491 carboxylic acid biosynthetic process#GO:0046394;regulation of hormone levels#GO:0010817;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;terpenoid metabolic process#GO:0006721;isoprenoid biosynthetic process#GO:0008299;oxoacid metabolic process#GO:0043436;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;biosynthetic process#GO:0009058;biological regulation#GO:0065007;aldehyde catabolic process#GO:0046185;hormone metabolic process#GO:0042445;lipid biosynthetic process#GO:0008610;terpenoid biosynthetic process#GO:0016114;diterpenoid biosynthetic process#GO:0016102;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;monocarboxylic acid biosynthetic process#GO:0072330 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 MONDO|Ensembl=ENSMODG00000017225.4|UniProtKB=F6RVX3 F6RVX3 PTHR15175:SF4 NEUTROPHIL CYTOSOLIC FACTOR 2, NEUTROPHIL NADPH OXIDASE FACTOR 2 NADPH OXIDASE ACTIVATOR 1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of reactive oxygen species metabolic process#GO:2000377;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;superoxide metabolic process#GO:0006801 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;catalytic complex#GO:1902494 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000049716.1|UniProtKB=A0A5F8GKS8 A0A5F8GKS8 MLX PTHR15741:SF25 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR MAX-LIKE PROTEIN X sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000049656.1|UniProtKB=A0A5F8HBV5 A0A5F8HBV5 LOC100020394 PTHR48002:SF45 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018459.4|UniProtKB=F7CU42 F7CU42 PTHR48015:SF22 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE PAK 2 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to starvation#GO:0042594;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to starvation#GO:0009267;regulation of MAPK cascade#GO:0043408;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cell migration#GO:0016477;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to nutrient levels#GO:0031667;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Ras Pathway#P04393>PAK#P04553;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;T cell activation#P00053>PAK#P01319;Angiogenesis#P00005>PAK#P00249 MONDO|Ensembl=ENSMODG00000007750.3|UniProtKB=F7BJH6 F7BJH6 LOC103094823 PTHR48001:SF15 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002115.3|UniProtKB=F6UG76 F6UG76 IL20 PTHR48482:SF2 INTERLEUKIN-19-RELATED INTERLEUKIN-20 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000008866.3|UniProtKB=F7CU24 F7CU24 UBXN2B PTHR23333:SF14 UBX DOMAIN CONTAINING PROTEIN UBX DOMAIN-CONTAINING PROTEIN 2B ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 microtubule cytoskeleton organization#GO:0000226;protein metabolic process#GO:0019538;localization#GO:0051179;organelle localization#GO:0051640;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;microtubule cytoskeleton organization involved in mitosis#GO:1902850;primary metabolic process#GO:0044238;cell cycle#GO:0007049;establishment of cell polarity#GO:0030010;modification-dependent protein catabolic process#GO:0019941;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;establishment of spindle localization#GO:0051293;spindle localization#GO:0051653;cellular localization#GO:0051641;establishment or maintenance of cell polarity#GO:0007163;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;establishment of organelle localization#GO:0051656;regulation of cell cycle#GO:0051726;cellular component organization#GO:0016043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;positive regulation of cell cycle#GO:0045787;proteasomal protein catabolic process#GO:0010498;cytoskeleton organization#GO:0007010;regulation of cell cycle process#GO:0010564;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000008630.4|UniProtKB=F6PGT5 F6PGT5 TGFB1 PTHR11848:SF125 TGF-BETA FAMILY TRANSFORMING GROWTH FACTOR BETA-1 PROPROTEIN signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 system development#GO:0048731;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;response to transforming growth factor beta#GO:0071559;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;circulatory system development#GO:0072359;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cell surface receptor signaling pathway#GO:0007166;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>TGFbeta#P06778;TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000001955.4|UniProtKB=F6VJ90 F6VJ90 OSTF1 PTHR24155:SF10 OSTEOCLAST-STIMULATING FACTOR 1 OSTEOCLAST-STIMULATING FACTOR 1 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 MONDO|Ensembl=ENSMODG00000045052.1|UniProtKB=A0A5F8G625 A0A5F8G625 PTHR22763:SF192 RING ZINC FINGER PROTEIN RING-TYPE DOMAIN-CONTAINING PROTEIN ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000017690.4|UniProtKB=F7G5L3 F7G5L3 PATL2 PTHR21551:SF3 TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1 PROTEIN PAT1 HOMOLOG 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 positive regulation of macromolecule metabolic process#GO:0010604;organelle organization#GO:0006996;mRNA catabolic process#GO:0006402;cellular component biogenesis#GO:0044085;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;mRNA metabolic process#GO:0016071;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;negative regulation of translation#GO:0017148;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;negative regulation of protein metabolic process#GO:0051248;primary metabolic process#GO:0044238;P-body assembly#GO:0033962;RNA decapping#GO:0110154;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;cellular component assembly#GO:0022607;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;membraneless organelle assembly#GO:0140694;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of gene expression#GO:0010468;catabolic process#GO:0009056;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;organelle assembly#GO:0070925 nucleus#GO:0005634;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000040868.1|UniProtKB=A0A5F8H8G7 A0A5F8H8G7 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000021332.4|UniProtKB=H9H7X6 H9H7X6 UNC93B1 PTHR46744:SF1 PROTEIN UNC-93 HOMOLOG B1 PROTEIN UNC-93 HOMOLOG B1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;protein transport#GO:0015031;cellular localization#GO:0051641;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;regulation of response to external stimulus#GO:0032101;intracellular protein transport#GO:0006886;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;regulation of response to biotic stimulus#GO:0002831;intracellular receptor signaling pathway#GO:0030522;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;localization#GO:0051179;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;macromolecule localization#GO:0033036;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;transport#GO:0006810;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;intracellular transport#GO:0046907;regulation of response to stress#GO:0080134;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;regulation of innate immune response#GO:0045088 intracellular organelle#GO:0043229;endosome#GO:0005768;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000000953.4|UniProtKB=F7F7N2 F7F7N2 PTHR23043:SF35 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA HIF-1 ALPHA C-TERMINAL TRANSACTIVATION DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;intracellular chemical homeostasis#GO:0055082;response to hypoxia#GO:0001666;regulation of gene expression#GO:0010468;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;response to abiotic stimulus#GO:0009628;cellular response to hypoxia#GO:0071456;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000006848.4|UniProtKB=A0A5F8HH10 A0A5F8HH10 LAPTM4B PTHR12479:SF6 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 4B regulation of membrane permeability#GO:0090559;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 lysosomal membrane#GO:0005765;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 MONDO|Ensembl=ENSMODG00000007931.3|UniProtKB=F7GI49 F7GI49 RAB4B PTHR47979:SF17 DRAB11-RELATED RAS-RELATED PROTEIN RAB-4B pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;regulation of endocytosis#GO:0030100;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;vesicle-mediated transport#GO:0016192;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;regulation of biological process#GO:0050789 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;recycling endosome#GO:0055037;intracellular organelle#GO:0043229;endosome#GO:0005768 G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000010857.3|UniProtKB=F7AR32 F7AR32 LOC100028830 PTHR11246:SF3 PRE-MRNA SPLICING FACTOR CROOKED NECK-LIKE PROTEIN 1 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;post-mRNA release spliceosomal complex#GO:0071014;nucleus#GO:0005634;protein-containing complex#GO:0032991 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000009413.4|UniProtKB=F7C5G1 F7C5G1 ITGA11 PTHR23220:SF21 INTEGRIN ALPHA INTEGRIN ALPHA-11 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 MONDO|Ensembl=ENSMODG00000043833.1|UniProtKB=A0A5F8GPK3 A0A5F8GPK3 PTHR24221:SF237 ATP-BINDING CASSETTE SUB-FAMILY B ANTIGEN PEPTIDE TRANSPORTER 2 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000003766.4|UniProtKB=F7AAK8 F7AAK8 ASB5 PTHR24136:SF18 SOWAH (DROSOPHILA) HOMOLOG ANKYRIN REPEAT AND SOCS BOX PROTEIN 5 positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;positive regulation of protein metabolic process#GO:0051247;protein modification by small protein conjugation or removal#GO:0070647;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;metabolic process#GO:0008152;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246 MONDO|Ensembl=ENSMODG00000048621.1|UniProtKB=A0A5F8H7W0 A0A5F8H7W0 BDKRB2 PTHR24228:SF25 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR B2 BRADYKININ RECEPTOR peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;regulation of anatomical structure size#GO:0090066;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;vasodilation#GO:0042311;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 MONDO|Ensembl=ENSMODG00000050775.1|UniProtKB=A0A5F8GJW8 A0A5F8GJW8 PTHR24390:SF290 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 184 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000029170.2|UniProtKB=A0A5F8GL55 A0A5F8GL55 PTHR46804:SF4 ADP RIBOSYLATION FACTOR LIKE GTPASE 14 EFFECTOR PROTEIN LIKE ARL14 EFFECTOR PROTEIN-LIKE small GTPase#PC00208;protein-binding activity modulator#PC00095;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000013518.4|UniProtKB=A0A5F8G1N5 A0A5F8G1N5 JAKMIP3 PTHR18935:SF9 GOLGIN SUBFAMILY A MEMBER 4-LIKE ISOFORM X1 JANUS KINASE AND MICROTUBULE-INTERACTING PROTEIN 3 MONDO|Ensembl=ENSMODG00000005604.3|UniProtKB=F7CZY0 F7CZY0 PTHR11108:SF1 FERROCHELATASE FERROCHELATASE, MITOCHONDRIAL lyase activity#GO:0016829;catalytic activity#GO:0003824 pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;cellular process#GO:0009987;tetrapyrrole biosynthetic process#GO:0033014;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;porphyrin-containing compound biosynthetic process#GO:0006779 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 lyase#PC00144 Heme biosynthesis#P02746>Ferrochelatase#P02972 MONDO|Ensembl=ENSMODG00000019023.2|UniProtKB=F7BLM2 F7BLM2 PPP1R3B PTHR12307:SF13 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3B protein binding#GO:0005515;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903;polysaccharide binding#GO:0030247;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899 regulation of glycogen biosynthetic process#GO:0005979;regulation of carbohydrate metabolic process#GO:0006109;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of polysaccharide metabolic process#GO:0032881;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000005358.3|UniProtKB=F6YLG2 F6YLG2 SLC25A11 PTHR45618:SF9 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL 2-OXOGLUTARATE_MALATE CARRIER PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000001603.4|UniProtKB=F7BAL7 F7BAL7 GUCY1A1 PTHR45655:SF4 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT ALPHA-1 phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824;guanylate cyclase activity#GO:0004383;lyase activity#GO:0016829 nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;response to oxygen levels#GO:0070482;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cyclic purine nucleotide metabolic process#GO:0052652;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;phosphorus metabolic process#GO:0006793;response to abiotic stimulus#GO:0009628;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;catalytic complex#GO:1902494 cyclase#PC00079;guanylate cyclase#PC00114 Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 MONDO|Ensembl=ENSMODG00000027481.2|UniProtKB=K7E3N7 K7E3N7 WFDC3 PTHR19441:SF102 WAP four-disulfide core domain protein ACTIVATED MACROPHAGE_MICROGLIA WAP DOMAIN PROTEIN-RELATED peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to other organism#GO:0051707;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;response to external stimulus#GO:0009605;defense response#GO:0006952 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000018066.4|UniProtKB=F7G487 F7G487 PTHR10836:SF111 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491;glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891 pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 Huntington disease#P00029>GAPDH#P00810;Glycolysis#P00024>Glyceraldehyde 3-phosphate dehydrogenase#P00676 MONDO|Ensembl=ENSMODG00000041290.1|UniProtKB=A0A5F8GPA9 A0A5F8GPA9 PTHR12884:SF18 60S RIBOSOMAL PROTEIN L29 60S RIBOSOMAL PROTEIN L29 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000049334.1|UniProtKB=A0A5F8HB43 A0A5F8HB43 PTHR11753:SF19 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-1 COMPLEX SUBUNIT SIGMA-2 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000011586.6|UniProtKB=F6XWM2 F6XWM2 NEMF PTHR15239:SF6 NUCLEAR EXPORT MEDIATOR FACTOR NEMF RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF nucleic acid binding#GO:0003676;binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;protein-containing complex binding#GO:0044877;tRNA binding#GO:0000049;ribosome binding#GO:0043022;ribosomal large subunit binding#GO:0043023 ubiquitin-dependent protein catabolic process#GO:0006511;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;translational elongation#GO:0006414;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organelle organization#GO:0006996;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;organelle disassembly#GO:1903008;modification-dependent macromolecule catabolic process#GO:0043632;translation#GO:0006412;protein catabolic process#GO:0030163;protein biosynthetic process#GO:0160307;catabolic process#GO:0009056;cytoplasmic translation#GO:0002181;rescue of stalled cytosolic ribosome#GO:0072344;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000001674.3|UniProtKB=F6SQP5 F6SQP5 PTHR45818:SF4 PROTEIN VAV GUANINE NUCLEOTIDE EXCHANGE FACTOR VAV2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;regulation of signal transduction#GO:0009966;immune response-regulating cell surface receptor signaling pathway#GO:0002768;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;intracellular signal transduction#GO:0035556;regulation of immune response#GO:0050776 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 B cell activation#P00010>vav#P00368;T cell activation#P00053>vav#P01295;PDGF signaling pathway#P00047>Vav#P01169 MONDO|Ensembl=ENSMODG00000005639.4|UniProtKB=A0A5F8HBA4 A0A5F8HBA4 AK1 PTHR23359:SF59 NUCLEOTIDE KINASE ADENYLATE KINASE ISOENZYME 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 MONDO|Ensembl=ENSMODG00000012205.4|UniProtKB=F7CE67 F7CE67 KIF20A PTHR24115:SF352 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF20A hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000012900.4|UniProtKB=A0A5F8GT69 A0A5F8GT69 PHKB PTHR10749:SF8 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT BETA protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 MONDO|Ensembl=ENSMODG00000017270.4|UniProtKB=F6T3N6 F6T3N6 MOSPD2 PTHR46384:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 organelle membrane contact site#GO:0044232;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000003375.5|UniProtKB=F6VA14 F6VA14 HSPB7 PTHR46907:SF2 HEAT SHOCK PROTEIN BETA-7-RELATED HEAT SHOCK PROTEIN BETA-7 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000028629.2|UniProtKB=K7E4A0 K7E4A0 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000016019.3|UniProtKB=A0A5F8GMK1 A0A5F8GMK1 NDUFS1 PTHR11615:SF377 NITRATE, FORMATE, IRON DEHYDROGENASE NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL NADH dehydrogenase activity#GO:0003954;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity, acting on NAD(P)H#GO:0016651;electron transfer activity#GO:0009055;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;active transmembrane transporter activity#GO:0022804;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075 electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120 organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;oxidoreductase complex#GO:1990204;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;respiratory chain complex I#GO:0045271;transporter complex#GO:1990351;organelle membrane#GO:0031090 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000014863.3|UniProtKB=F7BYD6 F7BYD6 STXBP4 PTHR19964:SF16 MULTIPLE PDZ DOMAIN PROTEIN SYNTAXIN-BINDING PROTEIN 4 protein binding#GO:0005515;syntaxin binding#GO:0019905;SNARE binding#GO:0000149;binding#GO:0005488 response to endogenous stimulus#GO:0009719;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000022858.3|UniProtKB=H9H9Q0 H9H9Q0 C7orf25 PTHR13379:SF0 UNCHARACTERIZED DUF1308 UPF0415 PROTEIN C7ORF25 MONDO|Ensembl=ENSMODG00000005023.4|UniProtKB=F7ERE2 F7ERE2 PTHR11662:SF207 SOLUTE CARRIER FAMILY 17 VESICULAR GLUTAMATE TRANSPORTER 3 carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313 signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;cell communication#GO:0007154;localization#GO:0051179;regulation of synapse structure or activity#GO:0050803;cellular localization#GO:0051641;trans-synaptic signaling#GO:0099537;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic signaling#GO:0099536;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;transport#GO:0006810;synaptic vesicle cycle#GO:0099504 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054;presynapse#GO:0098793;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;cytoplasm#GO:0005737;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202 secondary carrier transporter#PC00258 Ionotropic glutamate receptor pathway#P00037>Vglut#P01021 MONDO|Ensembl=ENSMODG00000002246.3|UniProtKB=F7DFE8 F7DFE8 CLDN2 PTHR12002:SF110 CLAUDIN CLAUDIN-2 transporter activity#GO:0005215;paracellular tight junction channel activity#GO:0160187 cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;transport#GO:0006810;cell-cell junction assembly#GO:0007043;cell adhesion#GO:0007155;cell-cell junction organization#GO:0045216;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;paracellular transport#GO:0160184;localization#GO:0051179 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000005404.3|UniProtKB=A0A5F8H337 A0A5F8H337 PCSK2 PTHR42884:SF13 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED NEUROENDOCRINE CONVERTASE 2 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;proteolysis#GO:0006508;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;peptide hormone processing#GO:0016486;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;hormone metabolic process#GO:0042445;gene expression#GO:0010467;protein maturation#GO:0051604;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;neuron projection#GO:0043005;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;Alzheimer disease-presenilin pathway#P00004>Furin#P00157 MONDO|Ensembl=ENSMODG00000018974.5|UniProtKB=F7CTC9 F7CTC9 ZNF318 PTHR15577:SF2 ZINC FINGER CONTAINING PROTEIN ZINC FINGER PROTEIN 318 positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000009964.4|UniProtKB=F6Y7X8 F6Y7X8 RIOK1 PTHR45723:SF5 SERINE/THREONINE-PROTEIN KINASE RIO1 SERINE_THREONINE-PROTEIN KINASE RIO1 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000014683.4|UniProtKB=A0A5F8GFA4 A0A5F8GFA4 ADAMTSL1 PTHR13723:SF157 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000003757.4|UniProtKB=F7DUZ0 F7DUZ0 MFSD10 PTHR23504:SF121 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 SOLUTE CARRIER FAMILY 75 MEMBER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cell projection membrane#GO:0031253;cluster of actin-based cell projections#GO:0098862;apical part of cell#GO:0045177;brush border membrane#GO:0031526;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;brush border#GO:0005903 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000012196.5|UniProtKB=A0A5F8H9N4 A0A5F8H9N4 GTF3C3 PTHR23082:SF0 TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 3-RELATED GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 3 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000022927.1|UniProtKB=F6PZA0 F6PZA0 LOC100617296 PTHR26450:SF146 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020727.3|UniProtKB=F7ANT2 F7ANT2 TECRL PTHR10556:SF27 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE TRANS-2,3-ENOYL-COA REDUCTASE-LIKE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000023132.3|UniProtKB=F7ED12 F7ED12 DGKG PTHR11255:SF36 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE GAMMA catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 signaling#GO:0023052;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;intracellular signal transduction#GO:0035556;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;biological regulation#GO:0065007;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637;neutral lipid metabolic process#GO:0006638;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;kinase#PC00137 MONDO|Ensembl=ENSMODG00000014398.3|UniProtKB=A0A5F8GV98 A0A5F8GV98 FAR2 PTHR11011:SF120 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000028155.2|UniProtKB=K7DZA2 K7DZA2 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000002928.4|UniProtKB=F6PMH2 F6PMH2 AZGP1 PTHR16675:SF289 MHC CLASS I-RELATED ZINC-ALPHA-2-GLYCOPROTEIN regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte mediated immunity#GO:0002708;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of immune system process#GO:0002684;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of leukocyte mediated immunity#GO:0002705 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000039483.1|UniProtKB=A0A5F8GB63 A0A5F8GB63 HIKESHI PTHR12925:SF2 HIKESHI FAMILY MEMBER PROTEIN HIKESHI protein binding#GO:0005515;Hsp70 protein binding#GO:0030544;binding#GO:0005488;molecular carrier activity#GO:0140104;protein-folding chaperone binding#GO:0051087;nucleocytoplasmic carrier activity#GO:0140142;heat shock protein binding#GO:0031072 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000049647.1|UniProtKB=A0A5F8H174 A0A5F8H174 PTHR15169:SF0 DAMAGE-SPECIFIC DNA BINDING PROTEIN 2 DNA DAMAGE-BINDING PROTEIN 2 damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 nucleobase-containing compound metabolic process#GO:0006139;response to radiation#GO:0009314;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;response to UV#GO:0009411;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;nucleic acid metabolic process#GO:0090304;cellular response to stress#GO:0033554 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 damaged DNA-binding protein#PC00086 p53 pathway#P00059>p48#G04705 MONDO|Ensembl=ENSMODG00000004677.4|UniProtKB=F6U6G7 F6U6G7 GMIP PTHR15228:SF16 SPERMATHECAL PHYSIOLOGY VARIANT GEM-INTERACTING PROTEIN enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;intracellular signal transduction#GO:0035556;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000004103.4|UniProtKB=F6VFA6 F6VFA6 MED30 PTHR31705:SF4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000020518.4|UniProtKB=A0A5F8GG54 A0A5F8GG54 ARAP2 PTHR45899:SF1 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;phosphatidylinositol phosphate binding#GO:1901981;enzyme activator activity#GO:0008047;phospholipid binding#GO:0005543;lipid binding#GO:0008289;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 regulation of actin filament-based process#GO:0032970;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000019461.5|UniProtKB=F6RWB3 F6RWB3 MAN2A2 PTHR11607:SF57 ALPHA-MANNOSIDASE ALPHA-MANNOSIDASE 2X hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 glycosidase#PC00110;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000015748.4|UniProtKB=A0A5F8GSC4 A0A5F8GSC4 SEZ6L2 PTHR45656:SF2 PROTEIN CBR-CLEC-78 SEIZURE 6-LIKE PROTEIN 2 cellular process#GO:0009987;cellular component organization#GO:0016043;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell junction organization#GO:0034330;developmental maturation#GO:0021700;developmental process#GO:0032502;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell body#GO:0044297;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000027767.2|UniProtKB=K7DYY0 K7DYY0 PTHR12307:SF40 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3F protein phosphatase binding#GO:0019903;protein binding#GO:0005515;carbohydrate binding#GO:0030246;enzyme binding#GO:0019899;phosphatase binding#GO:0019902;polysaccharide binding#GO:0030247;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of carbohydrate biosynthetic process#GO:0043255;biological regulation#GO:0065007;regulation of polysaccharide metabolic process#GO:0032881;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of glycogen biosynthetic process#GO:0005979;regulation of carbohydrate metabolic process#GO:0006109;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000039243.1|UniProtKB=A0A5F8H963 A0A5F8H963 SVBP PTHR34762:SF1 SMALL VASOHIBIN-BINDING PROTEIN SMALL VASOHIBIN-BINDING PROTEIN negative regulation of protein ubiquitination#GO:0031397;secretion by cell#GO:0032940;protein transport#GO:0015031;protein secretion#GO:0009306;localization#GO:0051179;regulation of post-translational protein modification#GO:1901873;secretion#GO:0046903;regulation of biological process#GO:0050789;protein localization to extracellular region#GO:0071692;negative regulation of biological process#GO:0048519;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of metabolic process#GO:0009892;export from cell#GO:0140352;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;transport#GO:0006810;regulation of protein ubiquitination#GO:0031396;negative regulation of cellular process#GO:0048523;regulation of protein modification process#GO:0031399;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;establishment of localization#GO:0051234;negative regulation of macromolecule metabolic process#GO:0010605;establishment of protein localization#GO:0045184;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177 MONDO|Ensembl=ENSMODG00000016950.2|UniProtKB=A0A5F8H3B2 A0A5F8H3B2 PTHR15840:SF10 CGI-121 FAMILY MEMBER EKC_KEOPS COMPLEX SUBUNIT TPRKB tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000038703.1|UniProtKB=A0A5F8G8R5 A0A5F8G8R5 PTHR12436:SF38 80 KDA MCM3-ASSOCIATED PROTEIN SAC3 DOMAIN-CONTAINING PROTEIN 1 nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;spindle organization#GO:0007051;cell cycle#GO:0007049;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;organelle assembly#GO:0070925;nucleocytoplasmic transport#GO:0006913;microtubule cytoskeleton organization#GO:0000226;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;metabolic process#GO:0008152;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;microtubule organizing center organization#GO:0031023;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;transcription export complex 2#GO:0070390;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000003446.4|UniProtKB=F7DWW2 F7DWW2 SLC25A34 PTHR45928:SF3 RE38146P SOLUTE CARRIER FAMILY 25 MEMBER 34 MONDO|Ensembl=ENSMODG00000020980.4|UniProtKB=F6S580 F6S580 ERG PTHR11849:SF216 ETS TRANSCRIPTIONAL REGULATOR ERG DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 MONDO|Ensembl=ENSMODG00000004468.4|UniProtKB=F6VRR3 F6VRR3 TSC22D4 PTHR47610:SF1 TSC22 DOMAIN FAMILY PROTEIN 4 TSC22 DOMAIN FAMILY PROTEIN 4 MONDO|Ensembl=ENSMODG00000037283.1|UniProtKB=A0A5F8H262 A0A5F8H262 PTHR11009:SF4 DER1-LIKE PROTEIN, DERLIN DERLIN-3 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to unfolded protein#GO:0006986;protein metabolic process#GO:0019538;signal transduction#GO:0007165;cellular process#GO:0009987;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000013464.4|UniProtKB=F7FYU4 F7FYU4 ZNF475 PTHR13555:SF67 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER PROTEIN 474 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000042553.1|UniProtKB=A0A5F8GNK2 A0A5F8GNK2 FBXO45 PTHR12245:SF7 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN F-BOX_SPRY DOMAIN-CONTAINING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 system development#GO:0048731;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;synapse assembly#GO:0007416;cell junction organization#GO:0034330;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;ubiquitin-dependent protein catabolic process#GO:0006511;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 cellular anatomical structure#GO:0110165;synapse#GO:0045202;protein-containing complex#GO:0032991;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;cell junction#GO:0030054;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000040284.1|UniProtKB=A0A5F8HFM1 A0A5F8HFM1 PTHR22880:SF143 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN-CONTAINING PROTEIN 4 chromatin-protein adaptor activity#GO:0140463;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000009077.3|UniProtKB=A0A5F8GKC8 A0A5F8GKC8 LOC100010218 PTHR11909:SF20 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of canonical Wnt signaling pathway#GO:0060828;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242;Hedgehog signaling pathway#P00025>Casein kinase I#P00681 MONDO|Ensembl=ENSMODG00000017115.4|UniProtKB=F6UJJ3 F6UJJ3 EFNA4 PTHR11304:SF42 EPHRIN EPHRIN-A4 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 intercellular signal molecule#PC00207;membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000017937.5|UniProtKB=A0A5F8GPT0 A0A5F8GPT0 SFPQ PTHR23189:SF51 RNA RECOGNITION MOTIF-CONTAINING SPLICING FACTOR, PROLINE- AND GLUTAMINE-RICH binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 alternative mRNA splicing, via spliceosome#GO:0000380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;regulation of DNA-templated transcription#GO:0006355;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions#GO:0000375;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000014822.2|UniProtKB=F7D292 F7D292 LOC100013689 PTHR48001:SF52 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013546.5|UniProtKB=A0A5F8GRE7 A0A5F8GRE7 PPP1R13B PTHR24131:SF5 APOPTOSIS-STIMULATING OF P53 PROTEIN APOPTOSIS-STIMULATING OF P53 PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515 apoptotic signaling pathway#GO:0097190;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;signal transduction by p53 class mediator#GO:0072331;intracellular signal transduction#GO:0035556;intrinsic apoptotic signaling pathway#GO:0097193;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;signaling#GO:0023052;regulation of cellular process#GO:0050794;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;response to stimulus#GO:0050896 nucleus#GO:0005634;cell-cell junction#GO:0005911;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;adherens junction#GO:0005912;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell junction#GO:0030054 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000005951.3|UniProtKB=F6WFU0 F6WFU0 COQ4 PTHR12922:SF10 UBIQUINONE BIOSYNTHESIS PROTEIN UBIQUINONE BIOSYNTHESIS PROTEIN COQ4 HOMOLOG, MITOCHONDRIAL lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000048698.1|UniProtKB=A0A5F8GWV3 A0A5F8GWV3 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000016109.3|UniProtKB=F7EAX1 F7EAX1 LOC100023238 PTHR26453:SF195 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014469.2|UniProtKB=F7A5I1 F7A5I1 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024086.3|UniProtKB=F7GGE9 F7GGE9 PTHR24377:SF1029 IP01015P-RELATED ZINC FINGER PROTEIN 135 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000043557.1|UniProtKB=A0A5F8G9Z7 A0A5F8G9Z7 PTHR28599:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 12 SMALL INTEGRAL MEMBRANE PROTEIN 12 MONDO|Ensembl=ENSMODG00000015555.5|UniProtKB=A0A5F8HIF6 A0A5F8HIF6 DNAH6 PTHR10676:SF339 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 6 microtubule motor activity#GO:0003777;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824 cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based process#GO:0007017;cilium-dependent cell motility#GO:0060285 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;catalytic complex#GO:1902494;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;dynein complex#GO:0030286 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000001457.4|UniProtKB=F7AQ53 F7AQ53 LOC100031587 PTHR22422:SF1 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 5B-RELATED TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 5B MONDO|Ensembl=ENSMODG00000003789.4|UniProtKB=F6ZKN9 F6ZKN9 TMCO3 PTHR16254:SF14 POTASSIUM/PROTON ANTIPORTER-RELATED SOLUTE CARRIER FAMILY 9 MEMBER D1 MONDO|Ensembl=ENSMODG00000020473.4|UniProtKB=F7FIY8 F7FIY8 OTOGL PTHR11339:SF225 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED OTOGELIN-LIKE PROTEIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000019056.4|UniProtKB=A0A5F8HB09 A0A5F8HB09 ZDHHC2 PTHR22883:SF207 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC2 catalytic activity, acting on a protein#GO:0140096;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 cell junction organization#GO:0034330;synapse assembly#GO:0007416;protein targeting#GO:0006605;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;anatomical structure development#GO:0048856;cellular localization#GO:0051641;localization#GO:0051179;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;localization within membrane#GO:0051668;synapse organization#GO:0050808;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;protein targeting to membrane#GO:0006612;developmental process#GO:0032502 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000004578.4|UniProtKB=F6R4B7 F6R4B7 AMPD1 PTHR11359:SF1 AMP DEAMINASE AMP DEAMINASE 1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824 IMP metabolic process#GO:0046040;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 deaminase#PC00088 MONDO|Ensembl=ENSMODG00000016274.4|UniProtKB=F7BGP1 F7BGP1 SLC44A1 PTHR12385:SF56 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000008873.4|UniProtKB=F7CAT6 F7CAT6 PTPN9 PTHR19134:SF285 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 9 phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000007717.4|UniProtKB=F6SW34 F6SW34 SLC25A3 PTHR45671:SF10 SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;phosphate transmembrane transporter activity#GO:0005315;active transmembrane transporter activity#GO:0022804 phosphate ion transport#GO:0006817;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 mitochondrial carrier protein#PC00158 MONDO|Ensembl=ENSMODG00000028380.2|UniProtKB=A0A5F8GC83 A0A5F8GC83 PTHR15076:SF15 CD99/MIC2 PROTEIN RELATED CD99 ANTIGEN positive regulation of locomotion#GO:0040017;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;cell migration#GO:0016477;biological regulation#GO:0065007;homotypic cell-cell adhesion#GO:0034109;regulation of locomotion#GO:0040012;cell-cell adhesion#GO:0098609;lymphocyte migration#GO:0072676;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of cell migration#GO:0030335;regulation of cell motility#GO:2000145;immune system process#GO:0002376;mononuclear cell migration#GO:0071674;cell adhesion#GO:0007155;regulation of leukocyte migration#GO:0002685;cell motility#GO:0048870;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000003063.4|UniProtKB=F6PNS3 F6PNS3 PIP5K1B PTHR23086:SF34 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE TYPE-1 BETA transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 kinase#PC00137;transferase#PC00220 MONDO|Ensembl=ENSMODG00000048176.1|UniProtKB=F7B4D3 F7B4D3 LOC100013937 PTHR26453:SF17 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000046813.1|UniProtKB=A0A5F8G267 A0A5F8G267 BOLA3 PTHR46188:SF1 BOLA-LIKE PROTEIN 3 BOLA-LIKE PROTEIN 3 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000018168.4|UniProtKB=F7CCF4 F7CCF4 ZDHHC23 PTHR22883:SF475 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC23 catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;establishment of protein localization to membrane#GO:0090150;protein localization to plasma membrane#GO:0072659;protein targeting#GO:0006605;localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;protein targeting to membrane#GO:0006612;intracellular protein localization#GO:0008104;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000025002.1|UniProtKB=F6TD48 F6TD48 SLC10A5 PTHR10361:SF29 SODIUM-BILE ACID COTRANSPORTER SODIUM_BILE ACID COTRANSPORTER 5 symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic cation transmembrane transporter activity#GO:0008324;bile acid transmembrane transporter activity#GO:0015125;solute:sodium symporter activity#GO:0015370;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075 lipid localization#GO:0010876;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;bile acid and bile salt transport#GO:0015721;establishment of localization#GO:0051234;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;macromolecule localization#GO:0033036;lipid transport#GO:0006869 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000049776.1|UniProtKB=A0A5F8HBV9 A0A5F8HBV9 UBE2D2 PTHR24068:SF330 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 D2 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000004964.3|UniProtKB=F7FL81 F7FL81 PTHR33663:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 177 COILED-COIL DOMAIN-CONTAINING PROTEIN 185 MONDO|Ensembl=ENSMODG00000003269.5|UniProtKB=F6SJ89 F6SJ89 PTPN14 PTHR45706:SF10 TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000040685.1|UniProtKB=A0A5F8GGG1 A0A5F8GGG1 LOC100618871 PTHR26453:SF232 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2A5 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012182.4|UniProtKB=F7CXZ4 F7CXZ4 PTHR45973:SF35 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 43 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000013380.3|UniProtKB=F7DSW9 F7DSW9 IL4I1 PTHR10742:SF21 FLAVIN MONOAMINE OXIDASE L-AMINO-ACID OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987 oxidase#PC00175 5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 MONDO|Ensembl=ENSMODG00000049963.1|UniProtKB=A0A5F8G5B2 A0A5F8G5B2 LOC100031238 PTHR24249:SF220 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 4 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888 response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to chemical#GO:0042221;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;defense response#GO:0006952 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000048199.1|UniProtKB=A0A5F8GUA7 A0A5F8GUA7 LOC100617657 PTHR26450:SF79 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001803.5|UniProtKB=A0A5F8G3C1 A0A5F8G3C1 RTN4 PTHR45799:SF1 RETICULON-LIKE PROTEIN RETICULON-4 endoplasmic reticulum membrane organization#GO:0090158;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;endoplasmic reticulum tubular network organization#GO:0071786 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 MONDO|Ensembl=ENSMODG00000009251.3|UniProtKB=H9H6B0 H9H6B0 LOC130455208 PTHR26452:SF292 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5G3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005032.4|UniProtKB=F7EQU7 F7EQU7 MARCHF7 PTHR14471:SF1 MARCH7/10 E3 UBIQUITIN PROTEIN LIGASE FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE MARCHF7 binding#GO:0005488;enzyme binding#GO:0019899;ubiquitin binding#GO:0043130;protein binding#GO:0005515 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000010462.4|UniProtKB=F7F7L0 F7F7L0 CRYBB2 PTHR11818:SF11 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN B2 structural molecule activity#GO:0005198 lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423;system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000040061.1|UniProtKB=A0A5F8GN13 A0A5F8GN13 LOC100028438 PTHR48002:SF97 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045199.1|UniProtKB=A0A5F8G5M0 A0A5F8G5M0 monDomV1R1207 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003922.3|UniProtKB=F6YTT8 F6YTT8 PTHR34829:SF1 SECRETOGLOBIN FAMILY 3A MEMBER 2 SECRETOGLOBIN FAMILY 3A MEMBER 1 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of cellular component organization#GO:0051130;positive regulation of biological process#GO:0048518 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000051279.1|UniProtKB=A0A5F8GGM6 A0A5F8GGM6 PTHR10010:SF23 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;phosphate transmembrane transporter activity#GO:0005315;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 homeostatic process#GO:0042592;phosphate ion transport#GO:0006817;localization#GO:0051179;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;inorganic anion transport#GO:0015698;cellular homeostasis#GO:0019725;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;transport#GO:0006810 apical part of cell#GO:0045177;cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;apical plasma membrane#GO:0016324;brush border#GO:0005903;cell periphery#GO:0071944;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000025090.2|UniProtKB=F6V8H9 F6V8H9 LOC100014211 PTHR10351:SF29 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 HOMOLOG 4 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000017516.4|UniProtKB=F7F0J1 F7F0J1 TCF21 PTHR23349:SF67 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 21 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000017215.4|UniProtKB=F6WYG5 F6WYG5 PTHR14938:SF2 HCLS1-ASSOCIATED PROTEIN X-1 HCLS1-ASSOCIATED PROTEIN X-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 regulation of actin filament length#GO:0030832;response to peptide#GO:1901652;regulation of biological quality#GO:0065008;regulation of organelle organization#GO:0033043;cellular response to cytokine stimulus#GO:0071345;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of actin cytoskeleton organization#GO:0032956;response to chemical#GO:0042221;response to cytokine#GO:0034097;cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament-based process#GO:0032970;regulation of actin filament organization#GO:0110053;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;clathrin-coated vesicle#GO:0030136;endoplasmic reticulum#GO:0005783;apical part of cell#GO:0045177;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;sarcoplasmic reticulum#GO:0016529;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;sarcoplasm#GO:0016528;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708;actin cytoskeleton#GO:0015629;vesicle#GO:0031982;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000024491.1|UniProtKB=F7E3I3 F7E3I3 LOC130456252 PTHR11437:SF69 RIBONUCLEASE RIBONUCLEASE A-DOMAIN DOMAIN-CONTAINING PROTEIN catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 response to external stimulus#GO:0009605;defense response#GO:0006952;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to Gram-positive bacterium#GO:0050830 endoribonuclease#PC00094;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000017787.4|UniProtKB=A0A5F8G242 A0A5F8G242 PTHR13476:SF0 CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6 CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6 transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;chromatin#GO:0000785;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000043794.1|UniProtKB=Q2ABA5 Q2ABA5 T2R3F PTHR11394:SF49 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 3 transmembrane signaling receptor activity#GO:0004888;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000049785.1|UniProtKB=A0A5F8HCS1 A0A5F8HCS1 NDUFB9 PTHR12868:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B22 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 9 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000002194.4|UniProtKB=F7GE36 F7GE36 GLT8D2 PTHR13778:SF2 GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000010161.4|UniProtKB=F6TAL6 F6TAL6 VTI1A PTHR21230:SF102 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1A binding#GO:0005488;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;SNAP receptor activity#GO:0005484 vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular process#GO:0009987;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;endosomal transport#GO:0016197;metabolic process#GO:0008152;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;cellular component organization#GO:0016043;cellular localization#GO:0051641;process utilizing autophagic mechanism#GO:0061919;post-Golgi vesicle-mediated transport#GO:0006892;macroautophagy#GO:0016236;membrane organization#GO:0061024;retrograde transport, endosome to Golgi#GO:0042147;membrane fusion#GO:0061025;establishment of localization#GO:0051234;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;catabolic process#GO:0009056;vesicle fusion#GO:0006906;intra-Golgi vesicle-mediated transport#GO:0006891;Golgi organization#GO:0007030;Golgi to vacuole transport#GO:0006896;localization#GO:0051179 coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506 SNARE protein#PC00034;membrane traffic protein#PC00150 Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042 MONDO|Ensembl=ENSMODG00000005719.4|UniProtKB=F6U312 F6U312 MED16 PTHR13224:SF6 THYROID HORMONE RECEPTOR-ASSOCIATED PROTEIN-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 16 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription initiation#GO:2000142;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000006868.4|UniProtKB=F6PX48 F6PX48 RGS8 PTHR10845:SF147 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 8 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695 negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 MONDO|Ensembl=ENSMODG00000042460.1|UniProtKB=A0A5F8G4Q3 A0A5F8G4Q3 PTHR11267:SF125 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX21 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;mononuclear cell migration#GO:0071674;immune system process#GO:0002376;cell migration#GO:0016477;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;lymphocyte migration#GO:0072676;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;leukocyte migration#GO:0050900;cell fate specification#GO:0001708;developmental process#GO:0032502 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 MONDO|Ensembl=ENSMODG00000014660.4|UniProtKB=A0A5F8H4V8 A0A5F8H4V8 KIDINS220 PTHR24116:SF0 KINASE D-INTERACTING SUBSTRATE OF 220 KDA KINASE D-INTERACTING SUBSTRATE OF 220 KDA enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cellular response to nerve growth factor stimulus#GO:1990090;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000016887.4|UniProtKB=F6XJB6 F6XJB6 SRMS PTHR24418:SF23 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SRMS protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;signaling receptor binding#GO:0005102;binding#GO:0005488;non-membrane spanning protein tyrosine kinase activity#GO:0004715;catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cell communication#GO:0007154;cellular developmental process#GO:0048869;enzyme-linked receptor protein signaling pathway#GO:0007167;developmental process#GO:0032502;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 MONDO|Ensembl=ENSMODG00000018479.4|UniProtKB=A0A5F8GAR7 A0A5F8GAR7 LTF PTHR11485:SF31 TRANSFERRIN SEROTRANSFERRIN immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542;transport#GO:0006810;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;defense response#GO:0006952;response to external stimulus#GO:0009605;establishment of localization#GO:0051234;antibacterial humoral response#GO:0019731;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;metal ion transport#GO:0030001;response to stimulus#GO:0050896;transition metal ion transport#GO:0000041;defense response to bacterium#GO:0042742;iron ion transport#GO:0006826;immune system process#GO:0002376;response to bacterium#GO:0009617;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179 recycling endosome#GO:0055037;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;extracellular region#GO:0005576;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000015044.3|UniProtKB=H9H6R5 H9H6R5 LSM4 PTHR23338:SF16 SMALL NUCLEAR RIBONUCLEOPROTEIN SM U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM4 snRNA binding#GO:0017069;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;P-body assembly#GO:0033962;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;organelle assembly#GO:0070925 membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U6 snRNP#GO:0005688;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;P-body#GO:0000932;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000023362.2|UniProtKB=F6XKU0 F6XKU0 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000046716.1|UniProtKB=A0A5F8HG52 A0A5F8HG52 LOC103106351 PTHR16675:SF67 MHC CLASS I-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000009213.3|UniProtKB=F7EEE6 F7EEE6 LOC100019585 PTHR26450:SF53 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51H1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000039920.1|UniProtKB=A0A5F8GZV0 A0A5F8GZV0 LOC100011978 PTHR23430:SF28 HISTONE H2A HISTONE H2A TYPE 1-C structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular component assembly#GO:0022607;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789 protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000018487.4|UniProtKB=F7C9W3 F7C9W3 PTHR12199:SF3 INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN 1 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000019105.4|UniProtKB=A0A5F8H662 A0A5F8H662 GC PTHR11385:SF11 SERUM ALBUMIN-RELATED VITAMIN D-BINDING PROTEIN small molecule binding#GO:0036094;binding#GO:0005488;steroid binding#GO:0005496;lipid binding#GO:0008289 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;vitamin D metabolic process#GO:0042359;response to nutrient levels#GO:0031667;primary metabolic process#GO:0044238;cellular process#GO:0009987;response to stimulus#GO:0050896;steroid metabolic process#GO:0008202 transfer/carrier protein#PC00219 Vitamin D metabolism and pathway#P04396>DBP#P04600 MONDO|Ensembl=ENSMODG00000008797.4|UniProtKB=A0A5F8G6F4 A0A5F8G6F4 NSMAF PTHR13743:SF123 BEIGE/BEACH-RELATED PROTEIN FAN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000039331.1|UniProtKB=A0A5F8H3J4 A0A5F8H3J4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000014579.6|UniProtKB=F7ASD0 F7ASD0 RAD23B PTHR10621:SF13 UV EXCISION REPAIR PROTEIN RAD23 LYSINE-SPECIFIC DEMETHYLASE RAD23B ubiquitin binding#GO:0043130;modification-dependent protein binding#GO:0140030;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000018937.3|UniProtKB=F7GJP0 F7GJP0 PTHR24070:SF395 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-1A hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 negative regulation of biological process#GO:0048519;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of neurotransmitter secretion#GO:0046928;signaling#GO:0023052;regulation of synaptic vesicle exocytosis#GO:2000300;cellular response to chemical stimulus#GO:0070887;regulation of neurotransmitter transport#GO:0051588;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;regulation of trans-synaptic signaling#GO:0099177;intracellular signaling cassette#GO:0141124;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular response to stimulus#GO:0051716;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of secretion#GO:0051046;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;regulation of exocytosis#GO:0017157;intracellular signal transduction#GO:0035556;cellular response to nitrogen compound#GO:1901699;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 MONDO|Ensembl=ENSMODG00000009375.4|UniProtKB=A0A5F8GDK7 A0A5F8GDK7 GNPAT PTHR12563:SF17 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746 lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000049250.1|UniProtKB=A0A5F8GAW4 A0A5F8GAW4 ARFIP2 PTHR12141:SF3 ARFAPTIN-RELATED ARFAPTIN-2 molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;trans-Golgi network membrane#GO:0032588;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791 vesicle coat protein#PC00235 Huntington disease#P00029>Arfaptin-2#P00793 MONDO|Ensembl=ENSMODG00000003994.4|UniProtKB=F7DSB8 F7DSB8 CCN3 PTHR11348:SF8 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 3 carbohydrate derivative binding#GO:0097367;cell adhesion molecule binding#GO:0050839;heparin binding#GO:0008201;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102;glycosaminoglycan binding#GO:0005539;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;tissue development#GO:0009888;chondrocyte differentiation#GO:0002062;biological regulation#GO:0065007;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;connective tissue development#GO:0061448;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;cell communication#GO:0007154;skeletal system development#GO:0001501;cartilage development#GO:0051216;system development#GO:0048731 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 MONDO|Ensembl=ENSMODG00000029272.2|UniProtKB=K7E2Y9 K7E2Y9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000016217.4|UniProtKB=H9H8J6 H9H8J6 NRTN PTHR12173:SF3 GDNF SUBFAMILY OF TGF-BETA FAMILY NEURTURIN signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;biological regulation#GO:0065007;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;generation of neurons#GO:0048699;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 neurotrophic factor#PC00163;intercellular signal molecule#PC00207;growth factor#PC00112 MONDO|Ensembl=ENSMODG00000049447.1|UniProtKB=H9H9J8 H9H9J8 PTHR24393:SF100 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 345-RELATED transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000017515.3|UniProtKB=F7F0J5 F7F0J5 TBPL1 PTHR10126:SF69 TATA-BOX BINDING PROTEIN TATA BOX-BINDING PROTEIN-LIKE 1 gene expression#GO:0010467;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187 general transcription factor#PC00259;RNA metabolism protein#PC00031 Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;General transcription by RNA polymerase I#P00022>TBP#P00657;General transcription by RNA polymerase I#P00022>SL1 complex#P00653;General transcription regulation#P00023>TBP#P00670 MONDO|Ensembl=ENSMODG00000003089.4|UniProtKB=F6PKN0 F6PKN0 DHRS1 PTHR44147:SF2 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 1 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 1 oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000012355.4|UniProtKB=F7E1U4 F7E1U4 TRAIP PTHR46569:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRAIP E3 UBIQUITIN-PROTEIN LIGASE TRAIP ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;replication fork processing#GO:0031297;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;DNA-templated DNA replication#GO:0006261;protein modification by small protein conjugation or removal#GO:0070647;DNA replication#GO:0006260;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211 chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000022596.3|UniProtKB=H9H875 H9H875 ISG15 PTHR10666:SF267 UBIQUITIN UBIQUITIN-LIKE PROTEIN ISG15 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein modification by small protein conjugation#GO:0032446;defense response to virus#GO:0051607;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;modification-dependent macromolecule catabolic process#GO:0043632;defense response to bacterium#GO:0042742;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;immune system process#GO:0002376;cellular process#GO:0009987;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;protein ubiquitination#GO:0016567;defense response to other organism#GO:0098542;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;ISG15-protein conjugation#GO:0032020;response to external biotic stimulus#GO:0043207;catabolic process#GO:0009056;response to bacterium#GO:0009617;response to virus#GO:0009615;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;immune response#GO:0006955;response to other organism#GO:0051707;post-translational protein modification#GO:0043687;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;nucleus#GO:0005634;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000009134.4|UniProtKB=F7EFG9 F7EFG9 MAP3K20 PTHR44329:SF320 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stress#GO:0033554;stress-activated MAPK cascade#GO:0051403;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stress#GO:0006950;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000044858.1|UniProtKB=A0A5F8HLQ1 A0A5F8HLQ1 LOC103092701 PTHR19303:SF27 TRANSPOSON HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016885.3|UniProtKB=F6XJF1 F6XJF1 LOC100619449 PTHR24377:SF878 IP01015P-RELATED ZINC FINGER PROTEIN 670 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004260.4|UniProtKB=F6TVK6 F6TVK6 AXIN2 PTHR46102:SF1 AXIN AXIN-2 kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;beta-catenin binding#GO:0008013;ubiquitin-like protein ligase binding#GO:0044389;ubiquitin protein ligase binding#GO:0031625 negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of cell cycle#GO:0051726;regulation of Wnt signaling pathway#GO:0030111;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of cell cycle process#GO:0010564;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;negative regulation of signal transduction#GO:0009968;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of protein metabolic process#GO:0051246;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;anatomical structure development#GO:0048856;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of catabolic process#GO:0009894;cellular developmental process#GO:0048869;positive regulation of catabolic process#GO:0009896;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Angiogenesis#P00005>Axin#P00253;Wnt signaling pathway#P00057>Axin#P01429 MONDO|Ensembl=ENSMODG00000012221.4|UniProtKB=A0A5F8GYG4 A0A5F8GYG4 ATXN2 PTHR12854:SF11 ATAXIN 2-RELATED ATAXIN-2 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 cellular component assembly#GO:0022607;cytoplasmic stress granule assembly#GO:0034063;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000044688.1|UniProtKB=A0A5F8G8N3 A0A5F8G8N3 SNX3 PTHR45963:SF1 RE52028P SORTING NEXIN-3 binding#GO:0005488;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;phosphatidylinositol-3-phosphate binding#GO:0032266 vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization within membrane#GO:0051668;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 MONDO|Ensembl=ENSMODG00000044731.1|UniProtKB=K7DZ13 K7DZ13 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000040839.1|UniProtKB=A0A5F8GG69 A0A5F8GG69 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001611.3|UniProtKB=F7BAG9 F7BAG9 SH2D4B PTHR14388:SF7 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 4B protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000043227.1|UniProtKB=K7E5F8 K7E5F8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012316.4|UniProtKB=F7EIS0 F7EIS0 PTHR11783:SF14 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1B1 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000013616.4|UniProtKB=F7G5C9 F7G5C9 AGK PTHR12358:SF116 SPHINGOSINE KINASE ACYLGLYCEROL KINASE, MITOCHONDRIAL kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 sphingoid biosynthetic process#GO:0046520;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000001027.3|UniProtKB=F6ZF90 F6ZF90 GRAMD2B PTHR46645:SF2 GRAM DOMAIN-CONTAINING PROTEIN 2B-RELATED GRAM DOMAIN-CONTAINING PROTEIN 2B supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881 MONDO|Ensembl=ENSMODG00000023180.2|UniProtKB=F7CN52 F7CN52 PTHR13025:SF5 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN-CONTAINING PROTEIN D1 molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000045739.1|UniProtKB=A0A5F8H854 A0A5F8H854 PFDN2 PTHR13303:SF0 PREFOLDIN SUBUNIT 2 PREFOLDIN SUBUNIT 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058 protein-containing complex#GO:0032991 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000015573.4|UniProtKB=F7AIP6 F7AIP6 TCF7L1 PTHR10373:SF25 TRANSCRIPTION FACTOR 7 FAMILY MEMBER TRANSCRIPTION FACTOR 7-LIKE 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 cell surface receptor signaling pathway#GO:0007166;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;chromatin#GO:0000785 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Wnt signaling pathway#P00057>TCF#P01437;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Gonadotropin-releasing hormone receptor pathway#P06664>TCF#P06701;Cadherin signaling pathway#P00012>TCF/LEF#P00465 MONDO|Ensembl=ENSMODG00000051435.1|UniProtKB=F6W387 F6W387 LOC100618111 PTHR26454:SF18 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C76 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013693.4|UniProtKB=F6QP11 F6QP11 AKT1 PTHR24356:SF171 SERINE/THREONINE-PROTEIN KINASE RAC-ALPHA SERINE_THREONINE-PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular response to chemical stimulus#GO:0070887;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;regulation of programmed cell death#GO:0043067;positive regulation of cell motility#GO:2000147;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;regulation of cell motility#GO:2000145;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;cellular response to insulin stimulus#GO:0032869;positive regulation of locomotion#GO:0040017;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;negative regulation of apoptotic process#GO:0043066;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;response to peptide hormone#GO:0043434 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>AKT#P06779;Hypoxia response via HIF activation#P00030>AKT#P00819;VEGF signaling pathway#P00056>Akt/PKB#P01408;Angiogenesis#P00005>Akt#P00223;Endothelin signaling pathway#P00019>Akt#P00589;FGF signaling pathway#P00021>Akt#P00632;Huntington disease#P00029>Akt#P00805;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AKT#P00827;EGF receptor signaling pathway#P00018>Akt#P00551;PI3 kinase pathway#P00048>PKB#P01179;FAS signaling pathway#P00020>ASK1#P00614;p53 pathway feedback loops 2#P04398>AKT#P04665;p53 pathway by glucose deprivation#P04397>Akt#P04641;T cell activation#P00053>Akt#P01332;p53 pathway#P00059>Akt#P01486;CCKR signaling map#P06959>AKT1#P07152;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>AKT#P00894;Apoptosis signaling pathway#P00006>AKT#P00260;Interleukin signaling pathway#P00036>PKB#P00973;Ras Pathway#P04393>AKT#P04570 MONDO|Ensembl=ENSMODG00000050374.1|UniProtKB=A0A5F8GI72 A0A5F8GI72 PTHR24286:SF397 CYTOCHROME P450 26 LANOSTEROL 14-ALPHA DEMETHYLASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451 lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;secondary alcohol biosynthetic process#GO:1902653;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281 oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000044552.1|UniProtKB=A0A5F8HLH0 A0A5F8HLH0 PTHR19282:SF216 TETRASPANIN TETRASPANIN-1 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000040523.1|UniProtKB=A0A5F8GWP1 A0A5F8GWP1 CTTNBP2NL PTHR23166:SF9 FILAMIN/GPBP-INTERACTING PROTEIN CTTNBP2 N-TERMINAL-LIKE PROTEIN intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179;protein localization to cytoskeleton#GO:0044380;macromolecule localization#GO:0033036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000014497.2|UniProtKB=F7FKJ6 F7FKJ6 OR1I1 PTHR48001:SF53 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1I1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008328.3|UniProtKB=A0A5F8H5P4 A0A5F8H5P4 THG1L PTHR12729:SF6 TRNA(HIS) GUANYLYLTRANSFERASE-RELATED TRNA(HIS) GUANYLYLTRANSFERASE-RELATED catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 MONDO|Ensembl=ENSMODG00000007964.4|UniProtKB=F7DRE7 F7DRE7 MYBL1 PTHR45614:SF9 MYB PROTEIN-RELATED MYB-RELATED PROTEIN A cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;mitotic cell cycle#GO:0000278;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;cell cycle#GO:0007049;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000007777.4|UniProtKB=F7AWT7 F7AWT7 PTHR24072:SF400 RHO FAMILY GTPASE RAS HOMOLOG FAMILY MEMBER D purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein kinase binding#GO:0019901;protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;cell migration#GO:0016477;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;regulation of cytoskeleton organization#GO:0051493;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789 cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000009201.4|UniProtKB=F6Z008 F6Z008 AGT PTHR11461:SF13 SERINE PROTEASE INHIBITOR, SERPIN ANGIOTENSINOGEN enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867 response to endogenous stimulus#GO:0009719;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>AngII#P05935 MONDO|Ensembl=ENSMODG00000025482.3|UniProtKB=A0A5F8G697 A0A5F8G697 PTHR11783:SF327 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1C4 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000013105.4|UniProtKB=F7BN09 F7BN09 SAV1 PTHR47522:SF2 SALVADOR FAMILY WW DOMAIN-CONTAINING PROTEIN 1 PROTEIN SALVADOR HOMOLOG 1 regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;positive regulation of apoptotic process#GO:0043065;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;negative regulation of cell population proliferation#GO:0008285;hippo signaling#GO:0035329;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000038744.1|UniProtKB=A0A5F8GJE2 A0A5F8GJE2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000004664.4|UniProtKB=F6U7F3 F6U7F3 HLX PTHR46808:SF1 H2.0-LIKE HOMEOBOX PROTEIN H2.0-LIKE HOMEOBOX PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000011929.4|UniProtKB=F7DET5 F7DET5 ADNP2 PTHR15740:SF2 NEUROPROTECTIVE PEPTIDE-CONTAINING PROTEIN ACTIVITY-DEPENDENT NEUROPROTECTOR HOMEOBOX PROTEIN 2 biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000039075.1|UniProtKB=K7E4R4 K7E4R4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009342.2|UniProtKB=F7GAN6 F7GAN6 PTHR13031:SF0 RIBONUCLEASE P SUBUNIT P30 RIBONUCLEASE P PROTEIN SUBUNIT P30 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 endonuclease complex#GO:1905348;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;multimeric ribonuclease P complex#GO:0030681;nucleolar ribonuclease P complex#GO:0005655;intracellular membrane-bounded organelle#GO:0043231 endoribonuclease#PC00094;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000047130.1|UniProtKB=A0A5F8H0H1 A0A5F8H0H1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000006181.4|UniProtKB=F6ZJR4 F6ZJR4 SLC16A13 PTHR11360:SF19 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 13 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000042869.1|UniProtKB=A0A5F8GDV8 A0A5F8GDV8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024637.3|UniProtKB=F6XU70 F6XU70 B3GALNT1 PTHR11214:SF153 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GALNAC:BETA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 1 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 metabolic process#GO:0008152;oligosaccharide biosynthetic process#GO:0009312;oligosaccharide metabolic process#GO:0009311;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000002184.3|UniProtKB=A0A5F8HJC6 A0A5F8HJC6 ZHX2 PTHR15467:SF5 ZINC-FINGERS AND HOMEOBOXES RELATED ZINC FINGERS AND HOMEOBOXES PROTEIN 2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000023260.1|UniProtKB=F6X789 F6X789 PPP1R3D PTHR12307:SF4 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3D enzyme binding#GO:0019899;polysaccharide binding#GO:0030247;phosphatase binding#GO:0019902;binding#GO:0005488;protein phosphatase binding#GO:0019903;protein binding#GO:0005515;carbohydrate binding#GO:0030246 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of polysaccharide metabolic process#GO:0032881;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of carbohydrate metabolic process#GO:0006109;regulation of glycogen biosynthetic process#GO:0005979;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000008468.3|UniProtKB=F7GER8 F7GER8 RMDN2 PTHR16056:SF15 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 2 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cytoskeleton#GO:0005856;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;mitotic spindle pole#GO:0097431;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;spindle microtubule#GO:0005876;microtubule#GO:0005874;mitochondrion#GO:0005739;spindle pole#GO:0000922;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000015289.4|UniProtKB=F6T6L9 F6T6L9 GPATCH11 PTHR21032:SF3 G PATCH DOMAIN-CONTAINING PROTEIN 11 G PATCH DOMAIN-CONTAINING PROTEIN 11 RNA metabolic process#GO:0016070;nervous system process#GO:0050877;sensory perception#GO:0007600;nucleic acid biosynthetic process#GO:0141187;visual perception#GO:0007601;RNA biosynthetic process#GO:0032774;sensory perception of light stimulus#GO:0050953;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;system process#GO:0003008;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;multicellular organismal process#GO:0032501;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000028099.2|UniProtKB=K7E4G8 K7E4G8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000040419.1|UniProtKB=A0A5F8GVT8 A0A5F8GVT8 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000037162.1|UniProtKB=A0A5F8GFC0 A0A5F8GFC0 TOMM6 PTHR15527:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM6 HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM6 HOMOLOG organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000049957.1|UniProtKB=A0A5F8HEF1 A0A5F8HEF1 LOC130458149 PTHR24390:SF250 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 763 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002288.4|UniProtKB=F7CC16 F7CC16 NASP PTHR15081:SF1 NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED NUCLEAR AUTOANTIGENIC SPERM PROTEIN protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromatin organization#GO:0006325;organelle assembly#GO:0070925;kinetochore assembly#GO:0051382;kinetochore organization#GO:0051383;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000038548.1|UniProtKB=F7DG75 F7DG75 LOC100022719 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001460.4|UniProtKB=F7APT5 F7APT5 BDP1 PTHR22929:SF0 RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR B TRANSCRIPTION FACTOR TFIIIB COMPONENT B'' HOMOLOG general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000018328.4|UniProtKB=F6PST2 F6PST2 PDIA5 PTHR45672:SF2 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED PROTEIN DISULFIDE-ISOMERASE A5 intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000021269.3|UniProtKB=F6T2V7 F6T2V7 PFN2 PTHR13936:SF15 PROFILIN PROFILIN-2 protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of actin filament bundle assembly#GO:0032233;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Profilin#P00521 MONDO|Ensembl=ENSMODG00000019076.3|UniProtKB=F7FNN8 F7FNN8 PTHR24070:SF455 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY SMALL MONOMERIC GTPASE hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;EGF receptor signaling pathway#P00018>Ras#P00552;PDGF signaling pathway#P00047>Ras#P01154;Ras Pathway#P04393>Ras#P04547;Integrin signalling pathway#P00034>Ras#P00916;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;VEGF signaling pathway#P00056>Ras#P01411;Angiogenesis#P00005>Ras#P00238;p53 pathway feedback loops 2#P04398>Ras#P04651;FGF signaling pathway#P00021>Ras#P00633 MONDO|Ensembl=ENSMODG00000021040.4|UniProtKB=F6W0D3 F6W0D3 SCAF4 PTHR23140:SF3 RNA PROCESSING PROTEIN LD23810P SR-RELATED AND CTD-ASSOCIATED FACTOR 4 RNA polymerase binding#GO:0070063;RNA polymerase core enzyme binding#GO:0043175;nucleic acid binding#GO:0003676;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;RNA binding#GO:0003723;RNA polymerase II complex binding#GO:0000993 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;regulation of biological process#GO:0050789;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of protein-containing complex disassembly#GO:0043244;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000023887.3|UniProtKB=A0A0B4J1D9 A0A0B4J1D9 PTHR23266:SF368 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823 immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000005256.5|UniProtKB=A0A5F8G4V7 A0A5F8G4V7 EBF4 PTHR10747:SF36 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE4 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 P53-like transcription factor#PC00253;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000009840.4|UniProtKB=F6WAQ4 F6WAQ4 SLC18A1 PTHR23506:SF31 GH10249P CHROMAFFIN GRANULE AMINE TRANSPORTER monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;solute:sodium symporter activity#GO:0015370;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;chloride transmembrane transporter activity#GO:0015108;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857 synaptic vesicle cycle#GO:0099504;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192 vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;axon terminus#GO:0043679;organelle membrane#GO:0031090;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;neuron projection terminus#GO:0044306;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;terminal bouton#GO:0043195;intracellular membrane-bounded organelle#GO:0043231;axon#GO:0030424;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory vesicle#GO:0099503;neuron projection#GO:0043005;presynapse#GO:0098793;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382 secondary carrier transporter#PC00258;transporter#PC00227 5HT1 type receptor mediated signaling pathway#P04373>5HT vesicular transporter#P04410;5HT4 type receptor mediated signaling pathway#P04376>5HT vesicular transporter#P04432;Adrenaline and noradrenaline biosynthesis#P00001>VAT1#P00071;5HT3 type receptor mediated signaling pathway#P04375>5HT vesicular transporter#P04424;5HT2 type receptor mediated signaling pathway#P04374>5HT vesicular transporter#P04418 MONDO|Ensembl=ENSMODG00000000241.3|UniProtKB=H9H5U8 H9H5U8 AQP5 PTHR19139:SF38 AQUAPORIN TRANSPORTER AQUAPORIN-5 water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 water transport#GO:0006833;localization#GO:0051179;establishment of localization#GO:0051234;fluid transport#GO:0042044;transport#GO:0006810 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transporter#PC00227 MONDO|Ensembl=ENSMODG00000014100.2|UniProtKB=F6QIY9 F6QIY9 CYREN PTHR14566:SF0 CELL CYCLE REGULATOR OF NON-HOMOLOGOUS END JOINING CELL CYCLE REGULATOR OF NON-HOMOLOGOUS END JOINING metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;chromosome#GO:0005694;site of double-strand break#GO:0035861;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000024111.3|UniProtKB=F6PWH1 F6PWH1 GPR158 PTHR32546:SF11 G-PROTEIN COUPLED RECEPTOR 158-RELATED METABOTROPIC GLYCINE RECEPTOR transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000016782.2|UniProtKB=F7G6I0 F7G6I0 STC1 PTHR11245:SF1 STANNIOCALCIN STANNIOCALCIN-1 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;calcium ion homeostasis#GO:0055074;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 MONDO|Ensembl=ENSMODG00000021243.4|UniProtKB=F6TJG1 F6TJG1 CHST2 PTHR10704:SF3 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;Golgi apparatus subcompartment#GO:0098791;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000029494.2|UniProtKB=K7E2R5 K7E2R5 PTHR23105:SF31 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER RIBOSOMAL L1 DOMAIN-CONTAINING PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000025446.3|UniProtKB=H9H9Q9 H9H9Q9 PTHR48071:SF39 SRCR DOMAIN-CONTAINING PROTEIN MACROPHAGE SCAVENGER RECEPTOR 1 MONDO|Ensembl=ENSMODG00000017342.4|UniProtKB=F6WFI7 F6WFI7 FRMPD4 PTHR46221:SF4 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 4 lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794;neuron projection#GO:0043005;dendritic spine#GO:0043197 MONDO|Ensembl=ENSMODG00000022923.2|UniProtKB=F6PZD0 F6PZD0 PTHR26450:SF64 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000162.4|UniProtKB=A0A5F8G282 A0A5F8G282 IQCE PTHR22590:SF3 MYOSIN MOTOR DOMAIN-CONTAINING PROTEIN IQ DOMAIN-CONTAINING PROTEIN E MONDO|Ensembl=ENSMODG00000020511.5|UniProtKB=H9H969 H9H969 MELTF PTHR11485:SF21 TRANSFERRIN MELANOTRANSFERRIN transition metal ion transport#GO:0000041;transport#GO:0006810;iron ion transport#GO:0006826;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;extracellular region#GO:0005576;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;recycling endosome#GO:0055037 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000018034.4|UniProtKB=F6ZWG8 F6ZWG8 POPDC1 PTHR12101:SF17 POPEYE DOMAIN CONTAINING PROTEIN POPEYE DOMAIN-CONTAINING PROTEIN 1 heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 developmental process#GO:0032502;striated muscle cell differentiation#GO:0051146;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of membrane potential#GO:0042391;animal organ development#GO:0048513;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;heart development#GO:0007507;multicellular organismal process#GO:0032501;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;circulatory system development#GO:0072359;cell differentiation#GO:0030154;muscle structure development#GO:0061061 sarcolemma#GO:0042383;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;apical junction complex#GO:0043296;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000038179.1|UniProtKB=A0A5F8G516 A0A5F8G516 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000012446.2|UniProtKB=A0A5F8G666 A0A5F8G666 PNPO PTHR10851:SF0 PYRIDOXINE-5-PHOSPHATE OXIDASE PYRIDOXINE-5'-PHOSPHATE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 organophosphate biosynthetic process#GO:0090407;pyridine-containing compound metabolic process#GO:0072524;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidase#PC00175;oxidoreductase#PC00176 Vitamin B6 metabolism#P02787>Pyridoxamine phosphate oxidase#P03236;Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine-5-phosphate oxidase#P03120;Pyridoxal phosphate salvage pathway#P02770>Pyridoxine-5-phosphate oxidase#P03123;Pyridoxal-5-phosphate biosynthesis#P02759>Pyridoxine-5-phosphate oxidase#P03061 MONDO|Ensembl=ENSMODG00000006008.4|UniProtKB=F6SKB2 F6SKB2 POGLUT2 PTHR12203:SF21 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED PROTEIN O-GLUCOSYLTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000009177.3|UniProtKB=F7AD31 F7AD31 OR9K2 PTHR26452:SF361 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000008677.4|UniProtKB=F6PJP1 F6PJP1 L1CAM PTHR45080:SF15 CONTACTIN 5 NEURAL CELL ADHESION MOLECULE L1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987;cell junction organization#GO:0034330;cell adhesion#GO:0007155;synapse organization#GO:0050808;cellular component organization or biogenesis#GO:0071840 axon#GO:0030424;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;cell body#GO:0044297;neuron projection#GO:0043005 MONDO|Ensembl=ENSMODG00000019656.3|UniProtKB=A0A5F8G3C5 A0A5F8G3C5 TRAPPC13 PTHR13134:SF3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000040574.1|UniProtKB=A0A5F8HBF5 A0A5F8HBF5 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000006976.5|UniProtKB=A0A5F8HBY4 A0A5F8HBY4 PTHR10480:SF1 PROTEIN UNC-13 HOMOLOG PROTEIN UNC-13 HOMOLOG A binding#GO:0005488;SNARE binding#GO:0000149;calmodulin binding#GO:0005516;protein binding#GO:0005515;syntaxin binding#GO:0019905 anterograde trans-synaptic signaling#GO:0098916;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;signal release#GO:0023061;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;vesicle localization#GO:0051648;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;calcium-ion regulated exocytosis#GO:0017156;signaling#GO:0023052;export from cell#GO:0140352;establishment of organelle localization#GO:0051656;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;secretion by cell#GO:0032940;cellular localization#GO:0051641;neurotransmitter transport#GO:0006836;synaptic transmission, glutamatergic#GO:0035249;establishment of vesicle localization#GO:0051650;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;exocytic process#GO:0140029;regulated exocytosis#GO:0045055 organelle membrane#GO:0031090;axon terminus#GO:0043679;neuromuscular junction#GO:0031594;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;axon#GO:0030424;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;neuron projection terminus#GO:0044306;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;terminal bouton#GO:0043195;intracellular membrane-bounded organelle#GO:0043231;synaptic membrane#GO:0097060;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;neuron projection#GO:0043005;presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular vesicle#GO:0097708;cell projection#GO:0042995;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000012744.4|UniProtKB=F6T186 F6T186 SURF6 PTHR14369:SF0 SURFEIT LOCUS PROTEIN 6 SURFEIT LOCUS PROTEIN 6 molecular condensate scaffold activity#GO:0140693;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 ribosomal small subunit biogenesis#GO:0042274;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000000601.2|UniProtKB=F6TBD9 F6TBD9 CCDC127 PTHR31958:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 127 COILED-COIL DOMAIN-CONTAINING PROTEIN 127 MONDO|Ensembl=ENSMODG00000012382.3|UniProtKB=F6PQ73 F6PQ73 PTHR23024:SF603 ARYLACETAMIDE DEACETYLASE ARYLACETAMIDE DEACETYLASE-LIKE 4 cellular anatomical structure#GO:0110165;membrane#GO:0016020 deacetylase#PC00087 MONDO|Ensembl=ENSMODG00000007303.4|UniProtKB=F7FBS3 F7FBS3 PSMA1 PTHR11599:SF244 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-1 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;proteasome complex#GO:0000502 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 MONDO|Ensembl=ENSMODG00000008713.3|UniProtKB=F7A794 F7A794 PTHR10177:SF70 CYCLINS G1_S-SPECIFIC CYCLIN-E2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;mitotic cell cycle phase transition#GO:0044772;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;cell cycle G1/S phase transition#GO:0044843;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;positive regulation of cell cycle G1/S phase transition#GO:1902808 cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 Parkinson disease#P00049>Cyclin E#P01213;Cell cycle#P00013>CdkC#P00489 MONDO|Ensembl=ENSMODG00000009355.3|UniProtKB=F7G0B4 F7G0B4 PDLIM2 PTHR24214:SF1 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 2 protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular component organization#GO:0016043;circulatory system development#GO:0072359;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;heart development#GO:0007507;multicellular organismal process#GO:0032501;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513 Z disc#GO:0030018;actomyosin#GO:0042641;contractile muscle fiber#GO:0043292;cell-cell junction#GO:0005911;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;actin filament#GO:0005884;I band#GO:0031674;cytoskeleton#GO:0005856;stress fiber#GO:0001725;adherens junction#GO:0005912;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cell junction#GO:0030054;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin filament bundle#GO:0032432;myofibril#GO:0030016 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000010755.4|UniProtKB=F7FWI0 F7FWI0 CPSF1 PTHR10644:SF26 DNA REPAIR/RNA PROCESSING CPSF FAMILY CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 1 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 RNA processing factor#PC00147;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000005242.4|UniProtKB=F6YNL8 F6YNL8 BCL2 PTHR11256:SF11 BCL-2 RELATED APOPTOSIS REGULATOR BCL-2 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267 cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway#GO:0097193;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;signaling#GO:0023052;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;release of cytochrome c from mitochondria#GO:0001836;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cell death#GO:0008219;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;regulation of cellular process#GO:0050794;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;apoptotic signaling pathway#GO:0097190;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066 organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867 Apoptosis signaling pathway#P00006>Bcl-2#P00270;Oxidative stress response#P00046>Bcl-2#P01123;CCKR signaling map#P06959>BCL2#P07059 MONDO|Ensembl=ENSMODG00000019434.4|UniProtKB=F6SFJ0 F6SFJ0 TMED3 PTHR22811:SF60 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 3 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;cellular component organization#GO:0016043;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179 intracellular organelle#GO:0043229;coated membrane#GO:0048475;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle#GO:0043226;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;COPI-coated vesicle#GO:0030137;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000019817.4|UniProtKB=A0A5F8H936 A0A5F8H936 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000043453.1|UniProtKB=A0A5F8GSQ0 A0A5F8GSQ0 PSMG1 PTHR15069:SF1 PROTEASOME ASSEMBLY CHAPERONE 1 PROTEASOME ASSEMBLY CHAPERONE 1 binding#GO:0005488;protein-containing complex binding#GO:0044877 chaperone-mediated protein complex assembly#GO:0051131;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular component assembly#GO:0022607 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;protein folding chaperone complex#GO:0101031;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000001019.4|UniProtKB=A0A5F8HIM2 A0A5F8HIM2 SPATA46 PTHR33517:SF4 PROTEIN FAM170B-RELATED SPERMATOGENESIS-ASSOCIATED PROTEIN 46 sexual reproduction#GO:0019953;reproductive process#GO:0022414;fertilization#GO:0009566 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear membrane#GO:0031965;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle envelope#GO:0031967;membrane#GO:0016020;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000009471.4|UniProtKB=F7FNT7 F7FNT7 NSUN6 PTHR22807:SF34 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING TRNA (CYTOSINE(72)-C(5))-METHYLTRANSFERASE NSUN6 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173 macromolecule modification#GO:0043412;RNA methylation#GO:0001510;methylation#GO:0032259;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA modification#GO:0000154;tRNA processing#GO:0008033;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA methylation#GO:0031167;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;rRNA metabolic process#GO:0016072;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;rRNA base methylation#GO:0070475;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000029017.2|UniProtKB=K7E425 K7E425 PTHR14352:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 7 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 7 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cell cycle process#GO:0022402;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226 HAUS complex#GO:0070652;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000010789.3|UniProtKB=F7CIH0 F7CIH0 CFP PTHR22906:SF43 PROPERDIN PROPERDIN MONDO|Ensembl=ENSMODG00000001152.6|UniProtKB=A0A5F8H017 A0A5F8H017 MCM5 PTHR11630:SF42 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM5 catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 DNA damage response#GO:0006974;DNA replication initiation#GO:0006270;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;DNA-templated DNA replication#GO:0006261;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 MONDO|Ensembl=ENSMODG00000017560.3|UniProtKB=A0A5F8GRU4 A0A5F8GRU4 PTHR20922:SF13 DNL-TYPE ZINC FINGER PROTEIN DNL-TYPE ZINC FINGER PROTEIN protein folding#GO:0006457;mitochondrial transport#GO:0006839;protein-containing complex assembly#GO:0065003;protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;mitochondrial transmembrane transport#GO:1990542;cellular component assembly#GO:0022607;protein maturation#GO:0051604;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;intracellular protein transmembrane transport#GO:0065002;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;protein localization to organelle#GO:0033365;primary metabolic process#GO:0044238;localization#GO:0051179;protein metabolic process#GO:0019538;chaperone-mediated protein complex assembly#GO:0051131;biosynthetic process#GO:0009058;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000015202.3|UniProtKB=F7BA17 F7BA17 PTHR45682:SF1 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE 3 hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;regulation of cell cycle#GO:0051726;regulation of lymphocyte activation#GO:0051249;regulation of MAPK cascade#GO:0043408;regulation of JNK cascade#GO:0046328;positive regulation of biological process#GO:0048518;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of cell-cell adhesion#GO:0022408;regulation of T cell activation#GO:0050863;positive regulation of cell cycle#GO:0045787;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;negative regulation of signal transduction#GO:0009968;negative regulation of lymphocyte activation#GO:0051250;negative regulation of T cell activation#GO:0050868;regulation of immune response#GO:0050776;negative regulation of multicellular organismal process#GO:0051241;negative regulation of MAPK cascade#GO:0043409;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of cell communication#GO:0010646;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of cell activation#GO:0050866;positive regulation of mitotic cell cycle#GO:0045931;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;negative regulation of cell adhesion#GO:0007162;regulation of cell adhesion#GO:0030155;negative regulation of response to stimulus#GO:0048585;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000003056.4|UniProtKB=F6PNX7 F6PNX7 ARL1 PTHR11711:SF41 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 1 nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf1#P00923 MONDO|Ensembl=ENSMODG00000009698.4|UniProtKB=F6YB55 F6YB55 DRG1 PTHR43127:SF1 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 1 ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000019018.2|UniProtKB=F7C5H5 F7C5H5 GNMT PTHR16458:SF2 GLYCINE N-METHYLTRANSFERASE GLYCINE N-METHYLTRANSFERASE methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;N-methyltransferase activity#GO:0008170 oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220;methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000042772.1|UniProtKB=A0A5F8HA56 A0A5F8HA56 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000051300.1|UniProtKB=A0A5F8GSD5 A0A5F8GSD5 monDomV1R1211 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013181.3|UniProtKB=A0A5F8H414 A0A5F8H414 CCR7 PTHR10489:SF635 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 7 immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;cytokine receptor activity#GO:0004896;protein binding#GO:0005515;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;cell communication#GO:0007154;chemotaxis#GO:0006935;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;locomotion#GO:0040011;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000013952.4|UniProtKB=F6RT32 F6RT32 LOC100022501 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 enzyme binding#GO:0019899;extracellular matrix structural constituent#GO:0005201;binding#GO:0005488;structural molecule activity#GO:0005198;protein binding#GO:0005515 sperm-egg recognition#GO:0035036;developmental process#GO:0032502;cellular developmental process#GO:0048869;cell-cell recognition#GO:0009988;single fertilization#GO:0007338;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of reproductive process#GO:2000241;oogenesis#GO:0048477;biological regulation#GO:0065007;cell recognition#GO:0008037;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;regulation of biological process#GO:0050789;gamete generation#GO:0007276;cell differentiation#GO:0030154;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;fertilization#GO:0009566;cell development#GO:0048468 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 MONDO|Ensembl=ENSMODG00000046946.1|UniProtKB=A0A5F8HI54 A0A5F8HI54 LOC100028436 PTHR26452:SF977 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000007792.3|UniProtKB=F7A943 F7A943 VAMP2 PTHR45701:SF5 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 2 syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488 vesicle fusion#GO:0006906;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;localization#GO:0051179;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membrane fusion#GO:0061025;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Circadian clock system#P00015>per#G01499;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Synaptic vesicle trafficking#P05734>Synaptobrevin#P05779;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Circadian clock system#P00015>Per#P00504;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Circadian clock system#P00015>per#G01503 MONDO|Ensembl=ENSMODG00000001640.4|UniProtKB=F6T882 F6T882 MCCC2 PTHR22855:SF13 ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED METHYLCROTONOYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ligase#PC00142;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000015975.4|UniProtKB=F7FCW1 F7FCW1 MAB21L4 PTHR10656:SF7 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MAB-21-LIKE 4 nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of double-strand break repair via homologous recombination#GO:0010569;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;regulation of DNA metabolic process#GO:0051052;positive regulation of metabolic process#GO:0009893;regulation of cellular response to stress#GO:0080135;regulation of DNA recombination#GO:0000018;cellular response to stress#GO:0033554;response to chemical#GO:0042221;regulation of multicellular organismal process#GO:0051239;response to stress#GO:0006950;positive regulation of response to external stimulus#GO:0032103;negative regulation of double-strand break repair via homologous recombination#GO:2000042;positive regulation of cytokine production#GO:0001819;regulation of response to biotic stimulus#GO:0002831;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;response to nitrogen compound#GO:1901698;cellular response to nitrogen compound#GO:1901699;negative regulation of DNA metabolic process#GO:0051053;activation of innate immune response#GO:0002218;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of innate immune response#GO:0045089;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of response to stress#GO:0080134;response to stimulus#GO:0050896;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of type I interferon production#GO:0032481;negative regulation of DNA recombination#GO:0045910;cellular response to stimulus#GO:0051716;regulation of double-strand break repair#GO:2000779;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;positive regulation of response to biotic stimulus#GO:0002833;negative regulation of cellular process#GO:0048523;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;DNA damage response#GO:0006974;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromosome#GO:0005694;site of double-strand break#GO:0035861;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 nucleotidyltransferase#PC00174;transferase#PC00220 MONDO|Ensembl=ENSMODG00000000315.4|UniProtKB=F6VV05 F6VV05 PTHR31915:SF8 SKICH DOMAIN-CONTAINING PROTEIN TAX1-BINDING PROTEIN 1 negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007 MONDO|Ensembl=ENSMODG00000008380.2|UniProtKB=A0A5F8H9R1 A0A5F8H9R1 PTHR21237:SF25 GRPE PROTEIN GRPE PROTEIN HOMOLOG 1, MITOCHONDRIAL molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589 intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585 mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000013694.3|UniProtKB=F6QP22 F6QP22 FBL PTHR10335:SF28 RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN RRNA 2'-O-METHYLTRANSFERASE FIBRILLARIN histone methyltransferase activity#GO:0042054;binding#GO:0005488;methyltransferase activity#GO:0008168;histone modifying activity#GO:0140993;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;nucleic acid binding#GO:0003676;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a rRNA#GO:0140102;RNA binding#GO:0003723;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on a protein#GO:0140096 rRNA processing#GO:0006364;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;rRNA methylation#GO:0031167;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000024668.3|UniProtKB=F7AGL6 F7AGL6 CATSPERE PTHR33722:SF3 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT DELTA-RELATED CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT EPSILON developmental process#GO:0032502;spermatogenesis#GO:0007283;flagellated sperm motility#GO:0030317;microtubule-based process#GO:0007017;cellular developmental process#GO:0048869;cell maturation#GO:0048469;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;sperm capacitation#GO:0048240;male gamete generation#GO:0048232;developmental maturation#GO:0021700;spermatid development#GO:0007286;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;sexual reproduction#GO:0019953;spermatid differentiation#GO:0048515;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;cilium-dependent cell motility#GO:0060285;sperm motility#GO:0097722;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cell differentiation#GO:0030154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;sperm flagellum#GO:0036126;cation channel complex#GO:0034703;transporter complex#GO:1990351;calcium channel complex#GO:0034704;plasma membrane protein complex#GO:0098797;sperm principal piece#GO:0097228;membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495 transporter#PC00227;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000045849.1|UniProtKB=A0A5F8G301 A0A5F8G301 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025543.3|UniProtKB=F6UJ92 F6UJ92 PTHR10068:SF16 BONE MARROW PROTEOGLYCAN BONE MARROW PROTEOGLYCAN extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000050965.1|UniProtKB=A0A5F8G7Q9 A0A5F8G7Q9 PTHR10489:SF958 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR 5 LIKE-RELATED transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930 calcium-mediated signaling#GO:0019722;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cell communication#GO:0007154;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;external side of plasma membrane#GO:0009897 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000009200.4|UniProtKB=F7CCH6 F7CCH6 TLE3 PTHR10814:SF24 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 3 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 MONDO|Ensembl=ENSMODG00000049526.1|UniProtKB=A0A5F8HAF1 A0A5F8HAF1 PTHR34349:SF1 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 32 STABILIZER OF AXONEMAL MICROTUBULES 4 protein binding#GO:0005515;enzyme binding#GO:0019899;phosphatase binding#GO:0019902;binding#GO:0005488 phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000011610.3|UniProtKB=F6UHF8 F6UHF8 NAB1 PTHR12623:SF9 NGFI-A BINDING PROTEIN NGFI-A-BINDING PROTEIN 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 Gonadotropin-releasing hormone receptor pathway#P06664>NAB#P06801 MONDO|Ensembl=ENSMODG00000023115.2|UniProtKB=F6ZLA0 F6ZLA0 PTHR23292:SF46 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR HOMOLOG metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;zinc ion binding#GO:0008270;ion binding#GO:0043167;transition metal ion binding#GO:0046914 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239 lysosomal membrane#GO:0005765;nucleus#GO:0005634;vesicle membrane#GO:0012506;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;cytoplasmic side of membrane#GO:0098562;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000046933.1|UniProtKB=F6XY90 F6XY90 PTHR19343:SF0 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 23_DELTA VARIABLE 6 binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000002120.4|UniProtKB=F6U118 F6U118 PTHR11860:SF59 POLYMERIC-IMMUNOGLOBULIN RECEPTOR IMMUNOGLOBULIN MU FC RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000006998.4|UniProtKB=A0A5F8HKE0 A0A5F8HKE0 FNBP1 PTHR15735:SF13 FCH AND DOUBLE SH3 DOMAINS PROTEIN FORMIN-BINDING PROTEIN 1 plasma membrane organization#GO:0007009;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000017925.4|UniProtKB=F7EKC6 F7EKC6 EPS8 PTHR12287:SF21 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE 8 protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 regulation of cell projection organization#GO:0031344;regulation of response to stimulus#GO:0048583;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of cellular component biogenesis#GO:0044089;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;intracellular signaling cassette#GO:0141124;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;positive regulation of cell projection organization#GO:0031346;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;regulation of cell projection assembly#GO:0060491;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;response to stimulus#GO:0050896;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646 membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;ruffle#GO:0001726;cell projection membrane#GO:0031253 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000002092.4|UniProtKB=A0A5F8H7D1 A0A5F8H7D1 RAPGEF2 PTHR45161:SF2 CYTOSKELETON-ASSOCIATED PROTEIN 4 RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 2 MONDO|Ensembl=ENSMODG00000005496.4|UniProtKB=F7AIF0 F7AIF0 TATDN2 PTHR46363:SF1 DEOXYRIBONUCLEASE TATDN2-RELATED 3'-5' RNA NUCLEASE TATDN2 endodeoxyribonuclease#PC00093 MONDO|Ensembl=ENSMODG00000002160.4|UniProtKB=A0A5F8G3M1 A0A5F8G3M1 PAPOLG PTHR10682:SF6 POLY A POLYMERASE POLY(A) POLYMERASE GAMMA adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000014071.3|UniProtKB=F6TST8 F6TST8 MMP15 PTHR10201:SF25 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-15 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;catabolic process#GO:0009056;cellular process#GO:0009987;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130;Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141 MONDO|Ensembl=ENSMODG00000019621.4|UniProtKB=F6XQ71 F6XQ71 RNF180 PTHR46717:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF180 E3 UBIQUITIN-PROTEIN LIGASE RNF180 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746 positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;catecholamine metabolic process#GO:0006584;regulation of protein catabolic process#GO:0042176;serotonin metabolic process#GO:0042428;positive regulation of protein catabolic process#GO:0045732;positive regulation of proteasomal protein catabolic process#GO:1901800;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;indole-containing compound metabolic process#GO:0042430;regulation of biological process#GO:0050789;phenol-containing compound metabolic process#GO:0018958;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;amine metabolic process#GO:0009308;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;biogenic amine metabolic process#GO:0006576;biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000014950.3|UniProtKB=F7FI80 F7FI80 CYP21A2 PTHR24281:SF318 STEROID 21-HYDROXYLASE-RELATED STEROID 21-HYDROXYLASE tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;binding#GO:0005488;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;steroid biosynthetic process#GO:0006694 hydroxylase#PC00122 MONDO|Ensembl=ENSMODG00000015156.4|UniProtKB=A0A5F8HGH0 A0A5F8HGH0 OPA1 PTHR11566:SF67 DYNAMIN DYNAMIN-LIKE GTPASE OPA1, MITOCHONDRIAL tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;protein binding#GO:0005515 organelle fusion#GO:0048284;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;mitochondrial intermembrane space#GO:0005758;cytoskeleton#GO:0005856;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000024892.1|UniProtKB=F6RD08 F6RD08 B3GALT2 PTHR11214:SF19 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 2 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000013501.2|UniProtKB=F7F8D6 F7F8D6 COPS9 PTHR28562:SF1 COP9 SIGNALOSOME COMPLEX SUBUNIT 9 COP9 SIGNALOSOME COMPLEX SUBUNIT 9 MONDO|Ensembl=ENSMODG00000010819.3|UniProtKB=F7BZB1 F7BZB1 PPIB PTHR11071:SF477 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000038423.1|UniProtKB=A0A5F8HED7 A0A5F8HED7 LOC100028465 PTHR48002:SF97 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000050317.1|UniProtKB=A0A5F8H3L1 A0A5F8H3L1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012716.4|UniProtKB=F6TYC2 F6TYC2 LYSMD4 PTHR20932:SF7 LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 4-RELATED MONDO|Ensembl=ENSMODG00000028392.2|UniProtKB=K7E657 K7E657 PTHR10037:SF221 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 9 SUBUNIT ALPHA channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;voltage-gated sodium channel activity#GO:0005248 cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;transport#GO:0006810;transmission of nerve impulse#GO:0019226;system process#GO:0003008;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;sodium ion transport#GO:0006814;action potential#GO:0001508;sensory perception of pain#GO:0019233;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;nervous system process#GO:0050877;sensory perception#GO:0007600;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154 plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;axon#GO:0030424;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cation channel complex#GO:0034703;transporter complex#GO:1990351 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000016769.4|UniProtKB=A0A5F8H2S6 A0A5F8H2S6 PTHR10442:SF24 40S RIBOSOMAL PROTEIN S21 SMALL RIBOSOMAL SUBUNIT PROTEIN ES21 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;maturation of 5.8S rRNA#GO:0000460;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;rRNA processing#GO:0006364;translation#GO:0006412;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000038042.1|UniProtKB=F7F345 F7F345 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000019813.2|UniProtKB=F6STH9 F6STH9 PTHR12411:SF902 CYSTEINE PROTEASE FAMILY C1-RELATED PROCATHEPSIN L catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000049191.1|UniProtKB=F7CT09 F7CT09 LOC100030307 PTHR26453:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G7 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009376.3|UniProtKB=F7CQ03 F7CQ03 ANO3 PTHR12308:SF16 ANOCTAMIN ANOCTAMIN-3 intramembrane lipid carrier activity#GO:0140303;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 MONDO|Gene=B2M|UniProtKB=Q864T8 Q864T8 B2M PTHR19944:SF62 MHC CLASS II-RELATED BETA-2-MICROGLOBULIN protein-containing complex binding#GO:0044877;binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277 regulation of lymphocyte activation#GO:0051249;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;immune system process#GO:0002376;regulation of multicellular organismal process#GO:0051239;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of T cell activation#GO:0050863;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of leukocyte activation#GO:0002696;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell adhesion#GO:0045785;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of cellular process#GO:0048522;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037 late endosome membrane#GO:0031902;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;late endosome#GO:0005770;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 MONDO|Ensembl=ENSMODG00000002117.3|UniProtKB=F6UG44 F6UG44 CHST11 PTHR12137:SF32 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 11 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 transferase#PC00220 MONDO|Ensembl=ENSMODG00000001703.1|UniProtKB=F6S6P8 F6S6P8 PTHR21353:SF8 FAMILY NOT NAMED CARDIOTROPHIN-2 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125 cell surface receptor signaling pathway#GO:0007166;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor signaling pathway via STAT#GO:0097696;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000002794.4|UniProtKB=F6YG07 F6YG07 PTHR24073:SF839 DRAB5-RELATED RAS-RELATED PROTEIN RAB-38 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;developmental pigmentation#GO:0048066;macromolecule localization#GO:0033036;cellular pigmentation#GO:0033059;developmental maturation#GO:0021700;developmental process#GO:0032502;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;response to external stimulus#GO:0009605;intracellular protein localization#GO:0008104;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell differentiation#GO:0030154;pigmentation#GO:0043473;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641 Golgi apparatus subcompartment#GO:0098791;melanosome#GO:0042470;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;mitochondrion#GO:0005739;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000041809.1|UniProtKB=F6UPJ4 F6UPJ4 PTHR48002:SF63 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038834.1|UniProtKB=A0A5F8GIW1 A0A5F8GIW1 IKZF5 PTHR24404:SF55 ZINC FINGER PROTEIN ZINC FINGER PROTEIN PEGASUS sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000040608.1|UniProtKB=A0A5F8GY16 A0A5F8GY16 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003321.2|UniProtKB=F7DYE9 F7DYE9 JUN PTHR11462:SF8 JUN TRANSCRIPTION FACTOR-RELATED TRANSCRIPTION FACTOR JUN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to steroid hormone#GO:0048545;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of cell cycle#GO:0051726;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;response to lipid#GO:0033993;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;positive regulation of transcription by RNA polymerase II#GO:0045944 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AP-1#P00838;T cell activation#P00053>jun#P01335;Angiogenesis#P00005>c-Jun#P00220;CCKR signaling map#P06959>JUN#G07276;Ras Pathway#P04393>AP1#P04560;Gonadotropin-releasing hormone receptor pathway#P06664>JUN#P06757;B cell activation#P00010>jun#P00401;FAS signaling pathway#P00020>c-Jun#P00601;Gonadotropin-releasing hormone receptor pathway#P06664>Junc#P06710;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;PDGF signaling pathway#P00047>c-Jun#P01163;Huntington disease#P00029>c-Jun#P00776;CCKR signaling map#P06959>JUN#G06983;Gonadotropin-releasing hormone receptor pathway#P06664>Junc#G06677;Toll receptor signaling pathway#P00054>AP1#P01355;CCKR signaling map#P06959>JUN#P07114;Apoptosis signaling pathway#P00006>c-Jun#P00303;Oxidative stress response#P00046>c-jun#P01132;Gonadotropin-releasing hormone receptor pathway#P06664>Junc#G06891 MONDO|Ensembl=ENSMODG00000048123.1|UniProtKB=A0A5F8G5L0 A0A5F8G5L0 PTHR19879:SF4 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;peptidase complex#GO:1905368;transferase complex#GO:1990234;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear DNA-directed RNA polymerase complex#GO:0055029;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;SAGA-type complex#GO:0070461;chromatin#GO:0000785;SAGA complex#GO:0000124;intracellular membraneless organelle#GO:0043232;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;acetyltransferase complex#GO:1902493 MONDO|Ensembl=ENSMODG00000050731.1|UniProtKB=A0A5F8GAI7 A0A5F8GAI7 PTHR31266:SF2 TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN A FAMILY MEMBER TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN A response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;regulation of innate immune response#GO:0045088;innate immune response#GO:0045087;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of innate immune response#GO:0045089;regulation of canonical NF-kappaB signal transduction#GO:0043122;activation of innate immune response#GO:0002218;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;intracellular receptor signaling pathway#GO:0030522;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;positive regulation of signal transduction#GO:0009967;immune response-activating signaling pathway#GO:0002757;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000051438.1|UniProtKB=A0A5F8GQ69 A0A5F8GQ69 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 transferase#PC00220 MONDO|Ensembl=ENSMODG00000020838.4|UniProtKB=F6R1I7 F6R1I7 PTHR24332:SF15 HOMEOBOX PROTEIN CDX HOMEOBOX PROTEIN CDX-4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;embryonic pattern specification#GO:0009880;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;tube development#GO:0035295;embryo development#GO:0009790;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;anterior/posterior axis specification#GO:0009948;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000010036.4|UniProtKB=F6TUG0 F6TUG0 GNAZ PTHR10218:SF65 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(Z) SUBUNIT ALPHA hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186 membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897 heterotrimeric G-protein#PC00117;G-protein#PC00020 Dopamine receptor mediated signaling pathway#P05912>GNAZ#P05964 MONDO|Ensembl=ENSMODG00000044079.1|UniProtKB=A0A5F8H3A9 A0A5F8H3A9 ABRAXAS2 PTHR31728:SF1 ABRAXAS FAMILY MEMBER BRISC COMPLEX SUBUNIT ABRAXAS 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;modification-dependent protein binding#GO:0140030;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593 organelle assembly#GO:0070925;organelle localization#GO:0051640;localization#GO:0051179;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;mitotic sister chromatid segregation#GO:0000070;mitotic spindle assembly#GO:0090307;nuclear division#GO:0000280;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic spindle organization#GO:0007052;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;attachment of spindle microtubules to kinetochore#GO:0008608;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000021009.3|UniProtKB=F6QZU6 F6QZU6 HLCS PTHR12835:SF5 BIOTIN PROTEIN LIGASE BIOTIN--PROTEIN LIGASE catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096;ligase activity, forming carbon-nitrogen bonds#GO:0016879 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ligase#PC00142 MONDO|Ensembl=ENSMODG00000002559.5|UniProtKB=A0A5F8GIL1 A0A5F8GIL1 AATK PTHR24417:SF0 SERINE/THREONINE-PROTEIN KINASE LMTK1 SERINE_THREONINE-PROTEIN KINASE LMTK1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 programmed cell death#GO:0012501;apoptotic process#GO:0006915;cell death#GO:0008219;central nervous system development#GO:0007417;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;neuron apoptotic process#GO:0051402;system development#GO:0048731;cellular process#GO:0009987;multicellular organismal process#GO:0032501;brain development#GO:0007420;nervous system development#GO:0007399;head development#GO:0060322;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000013530.3|UniProtKB=F7D6L5 F7D6L5 COQ9 PTHR21427:SF19 UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL lipid binding#GO:0008289;binding#GO:0005488 ketone metabolic process#GO:0042180;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000008013.3|UniProtKB=F7CL95 F7CL95 PTHR11216:SF29 EH DOMAIN INTERSECTIN-2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular localization#GO:0051641;localization#GO:0051179;synaptic vesicle endocytosis#GO:0048488;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;intracellular transport#GO:0046907;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;endosomal transport#GO:0016197;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000048042.1|UniProtKB=A0A5F8GXR8 A0A5F8GXR8 CST3 PTHR46186:SF2 CYSTATIN CYSTATIN-RELATED enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678 vesicle#GO:0031982;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000018179.4|UniProtKB=A0A5F8GJJ8 A0A5F8GJJ8 CSMD2 PTHR45656:SF6 PROTEIN CBR-CLEC-78 CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 2 multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;postsynaptic density assembly#GO:0097107;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;synapse assembly#GO:0007416;cell junction organization#GO:0034330;excitatory synapse assembly#GO:1904861;postsynapse organization#GO:0099173;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;anatomical structure development#GO:0048856;system development#GO:0048731;postsynaptic specialization organization#GO:0099084;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;postsynaptic density organization#GO:0097106;synapse organization#GO:0050808 cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;glutamatergic synapse#GO:0098978;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cell periphery#GO:0071944;membrane#GO:0016020;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794 MONDO|Ensembl=ENSMODG00000014856.4|UniProtKB=F7BYM9 F7BYM9 TNFSF11 PTHR11471:SF3 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 11 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of myeloid cell differentiation#GO:0045637;regulation of signaling#GO:0023051;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell differentiation#GO:0045597;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716;regulation of hemopoiesis#GO:1903706;cell communication#GO:0007154;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell development#GO:0060284;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of myeloid cell differentiation#GO:0045639;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;positive regulation of intracellular signal transduction#GO:1902533 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000001936.3|UniProtKB=F6VKC1 F6VKC1 PTHR11227:SF27 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 2 phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090 autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;energy derivation by oxidation of organic compounds#GO:0015980;pexophagy#GO:0000425;macromolecule metabolic process#GO:0043170;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;glycogen catabolic process#GO:0005980;vacuole organization#GO:0007033;localization#GO:0051179;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977 membrane#GO:0016020;phagophore assembly site#GO:0000407;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000009660.4|UniProtKB=F6Q891 F6Q891 DMTN PTHR24213:SF17 ACTIN-BINDING LIM PROTEIN DEMATIN binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular process#GO:0009987;cell projection assembly#GO:0030031;lamellipodium assembly#GO:0030032;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000040346.1|UniProtKB=A0A5F8G554 A0A5F8G554 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000027732.2|UniProtKB=K7E040 K7E040 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000020695.4|UniProtKB=F7DKD6 F7DKD6 PAICS PTHR43599:SF11 MULTIFUNCTIONAL PROTEIN ADE2 BIFUNCTIONAL PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE_PHOSPHORIBOSYLAMINOIMIDAZOLE SUCCINOCARBOXAMIDE SYNTHETASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;IMP metabolic process#GO:0046040;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000002761.4|UniProtKB=F6YH24 F6YH24 SLC24A5 PTHR10846:SF61 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 5 antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;plasma membrane#GO:0005886;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000010836.3|UniProtKB=F7BDF0 F7BDF0 PTHR10489:SF627 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 8 signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;locomotion#GO:0040011;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;chemotaxis#GO:0006935;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cell communication#GO:0007154 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000004890.4|UniProtKB=F7C2F7 F7C2F7 TMEM45B PTHR16007:SF59 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45B MONDO|Ensembl=ENSMODG00000047318.1|UniProtKB=A0A5F8GSF6 A0A5F8GSF6 C1QA PTHR15427:SF26 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q SUBCOMPONENT SUBUNIT A signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 regulation of immune response#GO:0050776;immune system process#GO:0002376;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;humoral immune response#GO:0006959;positive regulation of biological process#GO:0048518;immune response#GO:0006955;complement activation#GO:0006956;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;adaptive immune response#GO:0002250;positive regulation of response to stimulus#GO:0048584 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000008714.4|UniProtKB=F6PVV4 F6PVV4 MCMBP PTHR13489:SF0 MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN binding#GO:0005488;chromatin binding#GO:0003682 macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000015782.3|UniProtKB=F6Z4C5 F6Z4C5 LTA PTHR11471:SF31 TUMOR NECROSIS FACTOR FAMILY MEMBER LYMPHOTOXIN-ALPHA signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;signaling#GO:0023052;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;cell communication#GO:0007154;regulation of apoptotic signaling pathway#GO:2001233;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870;Apoptosis signaling pathway#P00006>TNF#P00259 MONDO|Ensembl=ENSMODG00000013916.4|UniProtKB=A0A5F8GTM4 A0A5F8GTM4 SPDEF PTHR11849:SF182 ETS SAM POINTED DOMAIN-CONTAINING ETS TRANSCRIPTION FACTOR DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 MONDO|Ensembl=ENSMODG00000038172.1|UniProtKB=A0A5F8GLN2 A0A5F8GLN2 UBE2J2 PTHR24068:SF135 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 J2 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein modification process#GO:0036211;response to stimulus#GO:0050896;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;response to chemical#GO:0042221 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>Ubc6#P01222 MONDO|Ensembl=ENSMODG00000001962.3|UniProtKB=F6V2H6 F6V2H6 MAPK6 PTHR24055:SF171 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 6 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 VEGF signaling pathway#P00056>MEK#P01402;PDGF signaling pathway#P00047>ERK#P01143;Angiogenesis#P00005>MEK#P00225;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Interleukin signaling pathway#P00036>ERK#P00965;Integrin signalling pathway#P00034>ERK#P00907 MONDO|Ensembl=ENSMODG00000046208.1|UniProtKB=A0A5F8G683 A0A5F8G683 TPPP2 PTHR12932:SF21 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN FAMILY MEMBER 2 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cellular component organization or biogenesis#GO:0071840;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of protein polymerization#GO:0032273;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;microtubule bundle formation#GO:0001578;positive regulation of cellular component organization#GO:0051130;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular component biogenesis#GO:0044087 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000049484.1|UniProtKB=A0A5F8G1S9 A0A5F8G1S9 LOC100026938 PTHR48018:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010254.3|UniProtKB=F6W632 F6W632 NHLRC3 PTHR24104:SF31 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED NHL REPEAT-CONTAINING PROTEIN 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 MONDO|Ensembl=ENSMODG00000003505.4|UniProtKB=F7C8K3 F7C8K3 ENTPD7 PTHR11782:SF37 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 7 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 nucleoside diphosphate metabolic process#GO:0009132;ribonucleotide metabolic process#GO:0009259;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;nucleotide metabolic process#GO:0009117;nucleoside diphosphate catabolic process#GO:0009134;ribonucleoside diphosphate metabolic process#GO:0009185;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 phosphatase#PC00181;hydrolase#PC00121;nucleotide phosphatase#PC00173 MONDO|Ensembl=ENSMODG00000049590.1|UniProtKB=A0A5F8G8V5 A0A5F8G8V5 SLC16A8 PTHR11360:SF26 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 3 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;monocarboxylic acid transmembrane transporter activity#GO:0008028 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 transporter#PC00227 MONDO|Ensembl=ENSMODG00000006807.3|UniProtKB=F6PGR5 F6PGR5 DHPS PTHR11703:SF0 DEOXYHYPUSINE SYNTHASE DEOXYHYPUSINE SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 biogenic amine metabolic process#GO:0006576;polyamine metabolic process#GO:0006595;cellular process#GO:0009987;metabolic process#GO:0008152;amine metabolic process#GO:0009308 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000011274.4|UniProtKB=F6WZZ5 F6WZZ5 HTR2A PTHR24247:SF30 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2A G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;synaptic signaling#GO:0099536;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;trans-synaptic signaling#GO:0099537;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to xenobiotic stimulus#GO:0009410;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268 plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414 MONDO|Ensembl=ENSMODG00000012251.4|UniProtKB=F6YGX4 F6YGX4 SLC22A13 PTHR24064:SF198 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000049848.1|UniProtKB=A0A5F8GKN6 A0A5F8GKN6 SUSD3 PTHR46879:SF1 SUSHI DOMAIN-CONTAINING PROTEIN 3 SUSHI DOMAIN-CONTAINING PROTEIN 3 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000017841.4|UniProtKB=F6Z8E8 F6Z8E8 LOC100029911 PTHR32261:SF4 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 6 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000048492.1|UniProtKB=F7DV22 F7DV22 PTHR23226:SF425 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 24 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017468.3|UniProtKB=F6Z545 F6Z545 PTHR11430:SF124 LIPOCALIN LIPOCALIN 1-LIKE PROTEIN 1-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000006219.4|UniProtKB=F7FS88 F7FS88 CHD8 PTHR45623:SF3 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD8 ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;histone binding#GO:0042393;DNA binding#GO:0003677;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of Wnt signaling pathway#GO:0030111;central nervous system development#GO:0007417;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of signal transduction#GO:0009968;head development#GO:0060322;nervous system development#GO:0007399;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of signal transduction#GO:0009966;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;tube development#GO:0035295;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585 transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000018007.2|UniProtKB=F7AL46 F7AL46 KCNA6 PTHR11537:SF104 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 6 monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;action potential#GO:0001508;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000014514.3|UniProtKB=F7F6R0 F7F6R0 LOC100016814 PTHR10196:SF69 SUGAR KINASE GLYCEROL KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate metabolic process#GO:0005975;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;alcohol metabolic process#GO:0006066;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;neutral lipid metabolic process#GO:0006638;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase#PC00137;carbohydrate kinase#PC00065 MONDO|Ensembl=ENSMODG00000001933.3|UniProtKB=F6W0P2 F6W0P2 GNAT2 PTHR10218:SF68 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-2 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 signal transduction#GO:0007165;cellular process#GO:0009987;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;biological regulation#GO:0065007;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;regulation of biological process#GO:0050789;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;detection of chemical stimulus involved in sensory perception#GO:0050907;cell communication#GO:0007154 plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;cilium#GO:0005929;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;photoreceptor inner segment#GO:0001917;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897 G-protein#PC00020;heterotrimeric G-protein#PC00117 Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;PI3 kinase pathway#P00048>Galpha#P01199 MONDO|Ensembl=ENSMODG00000007219.4|UniProtKB=F6WSI6 F6WSI6 MDM2 PTHR46858:SF13 OS05G0521000 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE MDM2 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;regulation of apoptotic process#GO:0042981;positive regulation of cell cycle#GO:0045787;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;positive regulation of mitotic cell cycle#GO:0045931;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;protein metabolic process#GO:0019538;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;regulation of intrinsic apoptotic signaling pathway#GO:2001242;modification-dependent protein catabolic process#GO:0019941 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 p53 pathway feedback loops 2#P04398>MDM-2#G04709;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#G04674;P53 pathway feedback loops 1#P04392>Mdm2#P04536;P53 pathway feedback loops 1#P04392>MDM-2#G04682;p53 pathway#P00059>Mdm2#P01483;Ubiquitin proteasome pathway#P00060>E3#P01490;p53 pathway#P00059>MDM-2#G01563;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#P04496;p53 pathway feedback loops 2#P04398>Mdm2#P04663 MONDO|Ensembl=ENSMODG00000002987.4|UniProtKB=F6Q4T5 F6Q4T5 DPH2 PTHR10762:SF2 DIPHTHAMIDE BIOSYNTHESIS PROTEIN 2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 2 cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 MONDO|Ensembl=ENSMODG00000039453.1|UniProtKB=A0A5F8GJY9 A0A5F8GJY9 HYKK PTHR21064:SF1 AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED HYDROXYLYSINE KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 MONDO|Ensembl=ENSMODG00000020261.4|UniProtKB=F7CJH8 F7CJH8 ZCCHC9 PTHR46242:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 ZCCHC9 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000036414.1|UniProtKB=F6Q011 F6Q011 PTHR26450:SF22 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51B6 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003135.6|UniProtKB=F6WVF1 F6WVF1 ABCC5 PTHR24223:SF196 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 5 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000017535.5|UniProtKB=F7E1H7 F7E1H7 CAMSAP1 PTHR21595:SF3 PATRONIN CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of protein depolymerization#GO:1901880;regulation of microtubule-based process#GO:0032886;supramolecular fiber organization#GO:0097435;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;microtubule cytoskeleton organization#GO:0000226;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;cellular component organization#GO:0016043;negative regulation of organelle organization#GO:0010639;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;cytoplasmic microtubule organization#GO:0031122 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;microtubule end#GO:1990752;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000009642.3|UniProtKB=F6QTD9 F6QTD9 FHIP2B PTHR21705:SF9 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK-INTERACTING PROTEIN 2B MONDO|Ensembl=ENSMODG00000016246.4|UniProtKB=F7A5M5 F7A5M5 LAMB1 PTHR10574:SF233 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-1 protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;signaling receptor binding#GO:0005102;binding#GO:0005488 cell motility#GO:0048870;cell-substrate adhesion#GO:0031589;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;external encapsulating structure organization#GO:0045229;system development#GO:0048731;axon development#GO:0061564;axon guidance#GO:0007411;cell migration#GO:0016477;tissue development#GO:0009888;extracellular matrix assembly#GO:0085029;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;generation of neurons#GO:0048699;cell adhesion#GO:0007155;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;substrate adhesion-dependent cell spreading#GO:0034446;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 MONDO|Ensembl=ENSMODG00000003985.4|UniProtKB=A0A5F8GPX1 A0A5F8GPX1 LOC100026465 PTHR24377:SF980 IP01015P-RELATED ZINC FINGER PROTEIN 420 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000036546.1|UniProtKB=A0A5F8GLX2 A0A5F8GLX2 PTHR11860:SF49 POLYMERIC-IMMUNOGLOBULIN RECEPTOR HIGH AFFINITY IMMUNOGLOBULIN ALPHA AND IMMUNOGLOBULIN MU FC RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000024584.1|UniProtKB=F6PGD3 F6PGD3 KCNJ10 PTHR11767:SF21 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10 ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873 import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000000074.4|UniProtKB=F6ZBK8 F6ZBK8 ASMT PTHR11746:SF362 O-METHYLTRANSFERASE ACETYLSEROTONIN O-METHYLTRANSFERASE transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-methyltransferase activity#GO:0008171 regulation of biological quality#GO:0065008;methylation#GO:0032259;metabolic process#GO:0008152;hormone biosynthetic process#GO:0042446;biosynthetic process#GO:0009058;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;regulation of hormone levels#GO:0010817;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987 methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000013899.4|UniProtKB=F6VS98 F6VS98 PTN PTHR13850:SF1 PLEIOTROPHIN FAMILY MEMBER PLEIOTROPHIN growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000005669.4|UniProtKB=F6VKQ2 F6VKQ2 LARP7 PTHR22792:SF159 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 7 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000021252.3|UniProtKB=F6TIT8 F6TIT8 PTHR11627:SF2 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE B catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832;fructose-bisphosphate aldolase activity#GO:0004332 ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 lyase#PC00144;aldolase#PC00044 Glycolysis#P00024>Aldolase#P00679;Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959 MONDO|Ensembl=ENSMODG00000000043.4|UniProtKB=F6YTG5 F6YTG5 DNAJB12 PTHR43908:SF8 AT29763P-RELATED DNAJ HOMOLOG SUBFAMILY B MEMBER 12 protein binding#GO:0005515;Hsp70 protein binding#GO:0030544;binding#GO:0005488;protein-folding chaperone binding#GO:0051087;heat shock protein binding#GO:0031072 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;cellular response to misfolded protein#GO:0071218;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;protein folding#GO:0006457;response to misfolded protein#GO:0051788;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000005476.4|UniProtKB=F7CG27 F7CG27 MRPL4 PTHR10746:SF18 50S RIBOSOMAL PROTEIN L4 LARGE RIBOSOMAL SUBUNIT PROTEIN UL4M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of Notch signaling pathway#GO:0045747;regulation of response to stimulus#GO:0048583;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000005101.4|UniProtKB=F6ZEC9 F6ZEC9 ZCCHC2 PTHR46939:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 2 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000005184.4|UniProtKB=F7DNG6 F7DNG6 NOP56 PTHR10894:SF0 NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58 NUCLEOLAR PROTEIN 56 binding#GO:0005488;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000022798.2|UniProtKB=H9H938 H9H938 LOC100020116 PTHR22894:SF1 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF170 MONDO|Ensembl=ENSMODG00000039229.1|UniProtKB=A0A5F8HCU9 A0A5F8HCU9 LOC100021601 PTHR26450:SF43 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025477.3|UniProtKB=F6QZI7 F6QZI7 SUSD5 PTHR32493:SF0 SUSHI DOMAIN-CONTAINING PROTEIN 5 SUSHI DOMAIN-CONTAINING PROTEIN 5 cell communication#GO:0007154;Notch signaling pathway#GO:0007219;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000024084.1|UniProtKB=F7GG65 F7GG65 CDC42EP2 PTHR15344:SF4 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 2 protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488;enzyme binding#GO:0019899 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344;regulation of actin filament-based process#GO:0032970;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cell projection assembly#GO:0060491;positive regulation of cell projection organization#GO:0031346;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of supramolecular fiber organization#GO:1902903;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;regulation of anatomical structure size#GO:0090066;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin cytoskeleton organization#GO:0032956;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of organelle organization#GO:0010638;Rho protein signal transduction#GO:0007266;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018195.4|UniProtKB=F7B743 F7B743 POGLUT1 PTHR12203:SF126 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED PROTEIN O-GLUCOSYLTRANSFERASE 1 xylosyltransferase activity#GO:0042285;glucosyltransferase activity#GO:0046527;pentosyltransferase activity#GO:0016763;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-xylosyltransferase activity#GO:0035252;hexosyltransferase activity#GO:0016758;UDP-glucosyltransferase activity#GO:0035251 regulation of response to stimulus#GO:0048583;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of Notch signaling pathway#GO:0045747 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000003308.4|UniProtKB=A0A5F8HFR9 A0A5F8HFR9 HOOK1 PTHR18947:SF36 HOOK PROTEINS PROTEIN HOOK HOMOLOG 1 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular component organization#GO:0016043;cytoplasmic microtubule organization#GO:0031122;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000000438.5|UniProtKB=F7FKR9 F7FKR9 EN1 PTHR24341:SF4 HOMEOBOX PROTEIN ENGRAILED HOMEOBOX PROTEIN ENGRAILED-1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 MONDO|Ensembl=ENSMODG00000023295.2|UniProtKB=F6VSN8 F6VSN8 PTHR11430:SF142 LIPOCALIN LIPOCALIN_CYTOSOLIC FATTY-ACID BINDING DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000010814.4|UniProtKB=H9H6F4 H9H6F4 ARHGAP8 PTHR45808:SF4 RHO GTPASE-ACTIVATING PROTEIN 68F RHO GTPASE-ACTIVATING PROTEIN 8 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of localization#GO:0032879;regulation of transport#GO:0051049;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;negative regulation of transport#GO:0051051;signaling#GO:0023052;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 VEGF signaling pathway#P00056>Rac#P01421;PDGF signaling pathway#P00047>Rho#P01174;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520;Angiogenesis#P00005>Rac#P00245 MONDO|Ensembl=ENSMODG00000000967.4|UniProtKB=F7ESY9 F7ESY9 UBXN6 PTHR23153:SF38 UBX-RELATED UBX DOMAIN-CONTAINING PROTEIN 6 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000009467.4|UniProtKB=A0A5F8GDT2 A0A5F8GDT2 PIAS1 PTHR10782:SF11 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS1 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;molecular function inhibitor activity#GO:0140678 negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of DNA-templated transcription#GO:0045892;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;protein sumoylation#GO:0016925;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;metabolic process#GO:0008152;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558 membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226 ubiquitin-protein ligase#PC00234 JAK/STAT signaling pathway#P00038>PIAS#P01031;Interferon-gamma signaling pathway#P00035>PIAS#P00958 MONDO|Ensembl=ENSMODG00000011862.4|UniProtKB=F7G343 F7G343 NABP1 PTHR13356:SF5 OB FOLD NUCLEIC ACID BINDING PROTEIN-RELATED SOSS COMPLEX SUBUNIT B2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;mitotic G2/M transition checkpoint#GO:0044818;response to radiation#GO:0009314;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;response to ionizing radiation#GO:0010212;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 MONDO|Ensembl=ENSMODG00000016933.5|UniProtKB=A0A5F8H7I3 A0A5F8H7I3 CACNA1H PTHR10037:SF192 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1H monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated sodium channel activity#GO:0005248;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;sodium channel activity#GO:0005272;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 biological regulation#GO:0065007;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;calcium ion transport#GO:0006816;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;regulation of cellular process#GO:0050794;calcium ion import#GO:0070509;action potential#GO:0001508;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of secretion#GO:0051046;monoatomic cation transport#GO:0006812;localization#GO:0051179;positive regulation of secretion#GO:0051047 cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;neuron projection#GO:0043005;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000009020.3|UniProtKB=F7BPL0 F7BPL0 PTHR11584:SF363 SERINE/THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 15 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;MAP kinase kinase kinase activity#GO:0004709;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of cellular process#GO:0050794;JNK cascade#GO:0007254;p38MAPK cascade#GO:0038066;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000020962.4|UniProtKB=A0A5F8GNJ9 A0A5F8GNJ9 FAM3B PTHR14592:SF2 UNCHARACTERIZED FAM3 PROTEIN FAM3B molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000025043.2|UniProtKB=F6W7R9 F6W7R9 PTHR11200:SF176 INOSITOL 5-PHOSPHATASE INOSITOL POLYPHOSPHATE 5-PHOSPHATASE OCRL hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;neuron projection#GO:0043005 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000045978.1|UniProtKB=A0A5F8H5G8 A0A5F8H5G8 NDUFA5 PTHR12653:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5 electron transport chain#GO:0022900;metabolic process#GO:0008152;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980 respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000008142.4|UniProtKB=F7ELK5 F7ELK5 NOX3 PTHR11972:SF12 NADPH OXIDASE NADPH OXIDASE 3 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664 defense response#GO:0006952;response to stimulus#GO:0050896;superoxide metabolic process#GO:0006801;cellular process#GO:0009987;metabolic process#GO:0008152;response to stress#GO:0006950;reactive oxygen species metabolic process#GO:0072593 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;catalytic complex#GO:1902494 oxidase#PC00175;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000002732.4|UniProtKB=F6Z7A1 F6Z7A1 ITCH PTHR11254:SF66 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE ITCHY HOMOLOG aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 MONDO|Ensembl=ENSMODG00000024645.2|UniProtKB=F6XBZ2 F6XBZ2 PTHR23291:SF133 BAX INHIBITOR-RELATED BAX INHIBITOR 1 passive transmembrane transporter activity#GO:0022803;enzyme inhibitor activity#GO:0004857;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;molecular function inhibitor activity#GO:0140678;calcium ion transmembrane transporter activity#GO:0015085 response to unfolded protein#GO:0006986;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;cellular response to unfolded protein#GO:0034620;negative regulation of apoptotic signaling pathway#GO:2001234;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;regulation of cell communication#GO:0010646;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;response to stress#GO:0006950;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227;ion channel#PC00133 Apoptosis signaling pathway#P00006>Bi1#P00277 MONDO|Ensembl=ENSMODG00000001208.4|UniProtKB=F7G7X1 F7G7X1 RGS5 PTHR10845:SF42 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 5 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of cell communication#GO:0010648;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 MONDO|Ensembl=ENSMODG00000003318.3|UniProtKB=F7DYG8 F7DYG8 TACSTD2 PTHR14168:SF5 TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER 2 cell adhesion#GO:0007155;negative regulation of cellular process#GO:0048523;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;negative regulation of cell adhesion#GO:0007162;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;regulation of biological process#GO:0050789;cellular process#GO:0009987;negative regulation of biological process#GO:0048519;cell-cell adhesion#GO:0098609 extracellular region#GO:0005576;apical junction complex#GO:0043296;anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000013088.4|UniProtKB=F7EXQ1 F7EXQ1 APOBEC2 PTHR13857:SF4 MRNA EDITING ENZYME C-U-EDITING ENZYME APOBEC-2 deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA modification#GO:0009451;metabolic process#GO:0008152;base conversion or substitution editing#GO:0016553;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cytidine to uridine editing#GO:0016554;nucleobase-containing compound metabolic process#GO:0006139 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000006592.4|UniProtKB=F7AKV7 F7AKV7 COQ6 PTHR43876:SF7 UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000043426.1|UniProtKB=A0A5F8GK07 A0A5F8GK07 PTHR19282:SF163 TETRASPANIN CD9 ANTIGEN cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000027352.2|UniProtKB=A0A5F8GNJ8 A0A5F8GNJ8 PTHR19339:SF0 T CELL RECEPTOR ALPHA VARIABLE 39 T CELL RECEPTOR ALPHA VARIABLE 41 MONDO|Ensembl=ENSMODG00000048622.1|UniProtKB=A0A5F8HCQ2 A0A5F8HCQ2 RAB25 PTHR47979:SF8 DRAB11-RELATED RAS-RELATED PROTEIN RAB-25 guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;exocytosis#GO:0006887;secretion by cell#GO:0032940;transport#GO:0006810;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000009217.4|UniProtKB=F7EEE3 F7EEE3 SPHK1 PTHR12358:SF47 SPHINGOSINE KINASE SPHINGOSINE KINASE 1 lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;regulation of cellular component organization#GO:0051128;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;response to growth factor#GO:0070848;sphingoid biosynthetic process#GO:0046520;cellular response to growth factor stimulus#GO:0071363;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;negative regulation of programmed cell death#GO:0043069;biosynthetic process#GO:0009058;biological regulation#GO:0065007;lipid biosynthetic process#GO:0008610;negative regulation of apoptotic process#GO:0043066;lipid metabolic process#GO:0006629;regulation of apoptotic process#GO:0042981;small molecule biosynthetic process#GO:0044283;regulation of endocytosis#GO:0030100;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;regulation of transport#GO:0051049;regulation of localization#GO:0032879 metabolite interconversion enzyme#PC00262;kinase#PC00137;transferase#PC00220 VEGF signaling pathway#P00056>SPK#P01404;Angiogenesis#P00005>SPK#P00229 MONDO|Ensembl=ENSMODG00000015361.5|UniProtKB=F6SGX8 F6SGX8 WNT10A PTHR12027:SF89 WNT RELATED PROTEIN WNT-10A protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;system development#GO:0048731;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 MONDO|Ensembl=ENSMODG00000012983.2|UniProtKB=F7CS84 F7CS84 CBLN1 PTHR22923:SF5 CEREBELLIN-RELATED CEREBELLIN-1 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006648.4|UniProtKB=F7G408 F7G408 HEY1 PTHR10985:SF78 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY_ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF PROTEIN 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of neuron differentiation#GO:0045664;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 MONDO|Ensembl=ENSMODG00000003535.4|UniProtKB=F7GBQ6 F7GBQ6 SDS PTHR48078:SF8 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED L-SERINE DEHYDRATASE_L-THREONINE DEAMINASE lyase activity#GO:0016829;catalytic activity#GO:0003824 proteinogenic amino acid biosynthetic process#GO:0170038;branched-chain amino acid biosynthetic process#GO:0009082;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 dehydratase#PC00091;lyase#PC00144 MONDO|Ensembl=ENSMODG00000010553.4|UniProtKB=F6YRN5 F6YRN5 RTN4RL1 PTHR24369:SF239 ANTIGEN BSP, PUTATIVE-RELATED RETICULON 4 RECEPTOR LIKE 1 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000002047.3|UniProtKB=F6QC34 F6QC34 PTHR10502:SF133 ANNEXIN ANNEXIN A8-RELATED small molecule binding#GO:0036094;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488;ion binding#GO:0043167;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;intracellular transport#GO:0046907;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;endosome organization#GO:0007032;endosomal transport#GO:0016197 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;sarcolemma#GO:0042383;vesicle#GO:0031982;nucleus#GO:0005634;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000008869.4|UniProtKB=F7CAZ5 F7CAZ5 ATP6AP1 PTHR12471:SF2 VACUOLAR ATP SYNTHASE SUBUNIT S1 V-TYPE PROTON ATPASE SUBUNIT S1 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;biological regulation#GO:0065007;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;intracellular chemical homeostasis#GO:0055082 catalytic complex#GO:1902494;ATPase complex#GO:1904949;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;proton-transporting V-type ATPase complex#GO:0033176;ATPase dependent transmembrane transport complex#GO:0098533;membrane protein complex#GO:0098796;membrane#GO:0016020;cation-transporting ATPase complex#GO:0090533;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ATP synthase#PC00002;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000013378.4|UniProtKB=F7DT90 F7DT90 OGFOD1 PTHR12117:SF0 HISTONE ACETYLTRANSFERASE COMPLEX PROLYL 3-HYDROXYLASE OGFOD1 dioxygenase activity#GO:0051213;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein-containing complex disassembly#GO:0043244 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000048789.1|UniProtKB=A0A5F8HIZ9 A0A5F8HIZ9 PEX26 PTHR16262:SF2 PEROXISOME ASSEMBLY PROTEIN 26 PEROXISOME ASSEMBLY PROTEIN 26 binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515 peroxisome organization#GO:0007031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;peroxisomal transport#GO:0043574;protein transport#GO:0015031;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000003797.3|UniProtKB=F6ZKE7 F6ZKE7 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008850.4|UniProtKB=A0A5F8G2K5 A0A5F8G2K5 DHX34 PTHR18934:SF278 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX34-RELATED ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;isomerase activity#GO:0016853;helicase activity#GO:0004386 regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000008526.4|UniProtKB=A0A5F8HAB2 A0A5F8HAB2 SLC35F3 PTHR19346:SF3 SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN SOLUTE CARRIER FAMILY 35 MEMBER F3 transport#GO:0006810;nitrogen compound transport#GO:0071705;vitamin transport#GO:0051180;establishment of localization#GO:0051234;localization#GO:0051179 MONDO|Ensembl=ENSMODG00000011533.2|UniProtKB=F6QXV8 F6QXV8 FAM136A PTHR21096:SF0 PROTEIN FAM136A TIM DOUBLE TWIN CX3C MOTIF PROTEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000051099.1|UniProtKB=A0A5F8GSK6 A0A5F8GSK6 SYCP3 PTHR19368:SF15 XLR/SCP3/FAM9 SYNAPTONEMAL COMPLEX PROTEIN 3 anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;spermatid differentiation#GO:0048515;sexual reproduction#GO:0019953;spermatid development#GO:0007286;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;cell cycle#GO:0007049;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cellular developmental process#GO:0048869;meiotic cell cycle#GO:0051321;developmental process#GO:0032502;spermatogenesis#GO:0007283;male gamete generation#GO:0048232;cellular process#GO:0009987 condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;synaptonemal structure#GO:0099086;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000019739.5|UniProtKB=F6X3T3 F6X3T3 LHX2 PTHR24208:SF80 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX2 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>LHX2#P06756 MONDO|Ensembl=ENSMODG00000014875.3|UniProtKB=F6YKU5 F6YKU5 DNAJC15 PTHR12763:SF7 FAMILY NOT NAMED DNAJ HOMOLOG SUBFAMILY C MEMBER 15 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671 protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594 cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000042419.1|UniProtKB=A0A5F8HL87 A0A5F8HL87 DISP1 PTHR45951:SF4 PROTEIN DISPATCHED-RELATED PROTEIN DISPATCHED HOMOLOG 1 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;smoothened signaling pathway#GO:0007224;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000008758.1|UniProtKB=F6PRL3 F6PRL3 PTHR45616:SF10 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 79 structural molecule activity#GO:0005198 developmental process#GO:0032502;epidermis development#GO:0008544;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;cellular component organization#GO:0016043;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000004305.4|UniProtKB=F6XNL7 F6XNL7 PTHR12801:SF152 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED ZGC:152968 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;catalytic activity#GO:0003824;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 exoribonuclease#PC00099;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000015183.4|UniProtKB=F7BWD5 F7BWD5 CASP8 PTHR10454:SF162 CASPASE CASPASE-8 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 apoptotic signaling pathway#GO:0097190;cellular developmental process#GO:0048869;developmental process#GO:0032502;positive regulation of neuron apoptotic process#GO:0043525;biological regulation#GO:0065007;hemopoiesis#GO:0030097;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;cell death#GO:0008219;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;positive regulation of apoptotic process#GO:0043065;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;signaling#GO:0023052;cell development#GO:0048468;extrinsic apoptotic signaling pathway#GO:0097191;cell differentiation#GO:0030154;response to stimulus#GO:0050896;myeloid cell differentiation#GO:0030099;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;mononuclear cell differentiation#GO:1903131;regulation of programmed cell death#GO:0043067;leukocyte differentiation#GO:0002521 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protease#PC00190 Apoptosis signaling pathway#P00006>Caspase 8#P00299;FAS signaling pathway#P00020>Caspase8#P00594;FAS signaling pathway#P00020>Pro-Caspase8#P00604;Huntington disease#P00029>Pro-caspase 8#P00767;Huntington disease#P00029>Caspase 8#P00808 MONDO|Ensembl=ENSMODG00000021219.3|UniProtKB=A0A5F8GS38 A0A5F8GS38 SPHKAP PTHR10226:SF7 A KINASE ANCHOR PROTEIN A-KINASE ANCHOR PROTEIN SPHKAP binding#GO:0005488;protein kinase A binding#GO:0051018;protein binding#GO:0005515 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000024245.2|UniProtKB=F7D5A0 F7D5A0 LOC100026143 PTHR26452:SF253 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10Q1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000039245.1|UniProtKB=A0A5F8HBQ8 A0A5F8HBQ8 PTHR19305:SF4 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 23 SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484;protein binding#GO:0005515 transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;synaptic vesicle membrane organization#GO:0048499;membrane fusion#GO:0061025;neurotransmitter secretion#GO:0007269;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;synaptic vesicle fusion to presynaptic active zone membrane#GO:0031629;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;anterograde trans-synaptic signaling#GO:0098916;vesicle fusion#GO:0006906;vesicle fusion to plasma membrane#GO:0099500;regulated exocytosis#GO:0045055;exocytic process#GO:0140029;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;exocytosis#GO:0006887;synaptic signaling#GO:0099536;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;organelle membrane fusion#GO:0090174;neurotransmitter transport#GO:0006836;endomembrane system organization#GO:0010256;cellular localization#GO:0051641;secretion by cell#GO:0032940;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;export from cell#GO:0140352;signaling#GO:0023052 plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423 MONDO|Ensembl=ENSMODG00000015264.3|UniProtKB=F6U355 F6U355 PTHR48034:SF1 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED TRANSFORMER-2 PROTEIN HOMOLOG BETA mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000040070.1|UniProtKB=A0A5F8HEC1 A0A5F8HEC1 PARK7 PTHR48094:SF25 PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED PARKINSON DISEASE PROTEIN 7 HOMOLOG catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;lyase activity#GO:0016829;oxidoreductase activity#GO:0016491;carbon-oxygen lyase activity#GO:0016835 response to toxic substance#GO:0009636;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;ketone metabolic process#GO:0042180;cellular detoxification of aldehyde#GO:0110095;monocarboxylic acid metabolic process#GO:0032787;cellular response to stimulus#GO:0051716;carboxylic acid biosynthetic process#GO:0046394;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;aldehyde catabolic process#GO:0046185;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;biosynthetic process#GO:0009058;response to stress#GO:0006950;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;alcohol biosynthetic process#GO:0046165;monocarboxylic acid biosynthetic process#GO:0072330;response to oxidative stress#GO:0006979;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 nucleus#GO:0005634;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000018546.3|UniProtKB=F7GCW4 F7GCW4 DDX43 PTHR47958:SF195 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000042358.1|UniProtKB=F7EKZ9 F7EKZ9 VN2R543 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013929.4|UniProtKB=F6SDA2 F6SDA2 RPS10 PTHR12146:SF10 40S RIBOSOMAL PROTEIN S10 SMALL RIBOSOMAL SUBUNIT PROTEIN ES10 structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000005555.4|UniProtKB=A0A5F8H9J7 A0A5F8H9J7 TMEM175 PTHR31462:SF5 ENDOSOMAL/LYSOSOMAL POTASSIUM CHANNEL TMEM175 ENDOSOMAL_LYSOSOMAL PROTON CHANNEL TMEM175 potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;lytic vacuole#GO:0000323 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000009682.4|UniProtKB=F6YBV4 F6YBV4 EPYC PTHR46269:SF3 EPIPHYCAN-RELATED EPIPHYCAN anatomical structure development#GO:0048856;animal organ development#GO:0048513;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;cartilage development#GO:0051216;connective tissue development#GO:0061448;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;tissue development#GO:0009888;multicellular organismal process#GO:0032501;bone development#GO:0060348 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000048303.1|UniProtKB=A0A5F8G861 A0A5F8G861 DSTYK PTHR46392:SF1 DUAL SERINE/THREONINE AND TYROSINE PROTEIN KINASE DUAL SERINE_THREONINE AND TYROSINE PROTEIN KINASE positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523;response to fibroblast growth factor#GO:0071774;positive regulation of MAPK cascade#GO:0043410;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;cellular response to fibroblast growth factor stimulus#GO:0044344;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of apoptotic process#GO:0042981;regulation of MAPK cascade#GO:0043408;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000021265.3|UniProtKB=F6T2Z9 F6T2Z9 TM4SF4 PTHR14198:SF15 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 4 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000017304.4|UniProtKB=F6S463 F6S463 GPM6B PTHR11683:SF10 MYELIN PROTEOLIPID NEURONAL MEMBRANE GLYCOPROTEIN M6-B structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;cell projection organization#GO:0030030;central nervous system development#GO:0007417;cell development#GO:0048468;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;gliogenesis#GO:0042063;myelination#GO:0042552;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;oligodendrocyte differentiation#GO:0048709;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;axon development#GO:0061564;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;myelin sheath#GO:0043209;plasma membrane#GO:0005886 myelin protein#PC00161 MONDO|Ensembl=ENSMODG00000020350.4|UniProtKB=A0A5F8GQ62 A0A5F8GQ62 VWCE PTHR47333:SF1 VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN response to biotic stimulus#GO:0009607;response to stimulus#GO:0050896;response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to external stimulus#GO:0009605;response to other organism#GO:0051707 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000015196.4|UniProtKB=F7BVQ1 F7BVQ1 PLCG2 PTHR10336:SF25 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2 phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;lipase activity#GO:0016298 intracellular signal transduction#GO:0035556;localization#GO:0051179;cell communication#GO:0007154;regulation of cell motility#GO:2000145;monoatomic cation transport#GO:0006812;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;metal ion transport#GO:0030001;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;phosphatidylinositol metabolic process#GO:0046488;transport#GO:0006810;lipid metabolic process#GO:0006629;regulation of cell migration#GO:0030334;positive regulation of locomotion#GO:0040017;establishment of localization#GO:0051234;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;organophosphate metabolic process#GO:0019637;regulation of locomotion#GO:0040012;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;positive regulation of cell motility#GO:2000147;calcium ion transmembrane transport#GO:0070588;signaling#GO:0023052;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;metabolic process#GO:0008152;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;monoatomic cation transmembrane transport#GO:0098655;glycerophospholipid metabolic process#GO:0006650 leading edge membrane#GO:0031256;ruffle membrane#GO:0032587;cell projection membrane#GO:0031253;ruffle#GO:0001726;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262;phospholipase#PC00186 VEGF signaling pathway#P00056>PLC-gamma#P01414;FGF signaling pathway#P00021>PLCgamma#P00638;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;B cell activation#P00010>PLC gamma2#P00388;Angiogenesis#P00005>PLC-gamma#P00256;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Axon guidance mediated by netrin#P00009>Phospholipase C#P00362;EGF receptor signaling pathway#P00018>PLCgamma#P00556;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;PDGF signaling pathway#P00047>PLCgamma#P01171;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412 MONDO|Ensembl=ENSMODG00000011892.4|UniProtKB=A0A5F8HCP1 A0A5F8HCP1 MIA2 PTHR23158:SF38 MELANOMA INHIBITORY ACTIVITY-RELATED MELANOMA INHIBITORY ACTIVITY PROTEIN 2 transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;secretion by cell#GO:0032940;secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;protein secretion#GO:0009306;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352 endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000014951.3|UniProtKB=F7FI75 F7FI75 NWD1 PTHR45013:SF1 NACHT DOMAIN- AND WD REPEAT-CONTAINING PROTEIN 1 NACHT DOMAIN- AND WD REPEAT-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000003411.4|UniProtKB=F6VQG1 F6VQG1 SPEN PTHR23189:SF48 RNA RECOGNITION MOTIF-CONTAINING MSX2-INTERACTING PROTEIN mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA splicing#GO:0043484;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of DNA-templated transcription#GO:0006355;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000012304.4|UniProtKB=F7EJ15 F7EJ15 ZNF236 PTHR24396:SF21 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 236 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000023630.3|UniProtKB=F6PJY0 F6PJY0 LOC100019400 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000033067.2|UniProtKB=A0A5F8GDX6 A0A5F8GDX6 AARD PTHR32289:SF2 PROTEIN FAM167A ALANINE- AND ARGININE-RICH DOMAIN-CONTAINING PROTEIN response to lipid#GO:0033993;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700 MONDO|Ensembl=ENSMODG00000001369.3|UniProtKB=A0A5F8GCW4 A0A5F8GCW4 AQR PTHR10887:SF5 DNA2/NAM7 HELICASE FAMILY RNA HELICASE AQUARIUS RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000010420.3|UniProtKB=F7A6S5 F7A6S5 VPS36 PTHR13128:SF12 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36 localization#GO:0051179;protein metabolic process#GO:0019538;protein localization to vacuole#GO:0072665;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;macromolecule localization#GO:0033036;protein transport#GO:0015031;cellular localization#GO:0051641;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization to vacuole#GO:0072666;endosomal transport#GO:0016197;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 vesicle membrane#GO:0012506;membrane#GO:0016020;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 membrane traffic protein#PC00150 MONDO|Gene=DUSP29|UniProtKB=P0C593 P0C593 DUSP29 PTHR45682:SF6 AGAP008228-PA DUAL SPECIFICITY PHOSPHATASE 29 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000018341.4|UniProtKB=F6PR65 F6PR65 MYLK PTHR47633:SF1 IMMUNOGLOBULIN MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 muscle contraction#GO:0006936;muscle system process#GO:0003012;multicellular organismal process#GO:0032501;system process#GO:0003008 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;stress fiber#GO:0001725;cytoskeleton#GO:0005856;cleavage furrow#GO:0032154;membraneless organelle#GO:0043228;cell periphery#GO:0071944;actomyosin#GO:0042641;cell leading edge#GO:0031252;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cell division site#GO:0032153;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;lamellipodium#GO:0030027 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877;Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514 MONDO|Ensembl=ENSMODG00000027892.2|UniProtKB=K7E453 K7E453 LOC100032600 PTHR10454:SF13 CASPASE CASPASE-4 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197 inflammatory response#GO:0006954;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cell death#GO:0008219;apoptotic process#GO:0006915;positive regulation of apoptotic process#GO:0043065;positive regulation of response to external stimulus#GO:0032103;defense response#GO:0006952;positive regulation of neuron apoptotic process#GO:0043525;positive regulation of inflammatory response#GO:0050729;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;canonical inflammasome complex#GO:0061702;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000045171.1|UniProtKB=A0A5F8G5R3 A0A5F8G5R3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000022836.2|UniProtKB=H9H9J7 H9H9J7 PTHR11205:SF60 RIBOSOMAL PROTEIN S7 RIBOSOMAL_S7 DOMAIN-CONTAINING PROTEIN ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000008663.6|UniProtKB=F6PG47 F6PG47 LARP1 PTHR22792:SF51 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000015650.3|UniProtKB=F7F0U2 F7F0U2 SULT1A2 PTHR11783:SF324 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1A2 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000015397.3|UniProtKB=F6TJW4 F6TJW4 RNF25 PTHR13198:SF4 RING FINGER PROTEIN 25 E3 UBIQUITIN-PROTEIN LIGASE RNF25 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 protein catabolic process#GO:0030163;translation#GO:0006412;modification-dependent macromolecule catabolic process#GO:0043632;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;rescue of stalled cytosolic ribosome#GO:0072344;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;catabolic process#GO:0009056;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;translational elongation#GO:0006414;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organelle organization#GO:0006996;biosynthetic process#GO:0009058;gene expression#GO:0010467 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000016753.4|UniProtKB=F7GGL1 F7GGL1 LAMA5 PTHR10574:SF448 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-5 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;neuron projection development#GO:0031175;axon guidance#GO:0007411;axon development#GO:0061564;cellular process#GO:0009987;multicellular organismal process#GO:0032501;tissue development#GO:0009888;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 MONDO|Ensembl=ENSMODG00000015928.4|UniProtKB=F6ZQM3 F6ZQM3 IDH1 PTHR11822:SF44 NADP-SPECIFIC ISOCITRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC pyridine-containing compound metabolic process#GO:0072524;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;NADP+ metabolic process#GO:0006739;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;microbody#GO:0042579;peroxisome#GO:0005777;cytosol#GO:0005829 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000017127.4|UniProtKB=F6U3E7 F6U3E7 ZBTB7B PTHR46105:SF4 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 7B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011562.3|UniProtKB=F6QBL8 F6QBL8 TGFA PTHR10740:SF1 TRANSFORMING GROWTH FACTOR ALPHA PROTRANSFORMING GROWTH FACTOR ALPHA binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;positive regulation of cellular component organization#GO:0051130;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of organelle organization#GO:0010638;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;ERBB signaling pathway#GO:0038127;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cell cycle#GO:0045787;regulation of nuclear division#GO:0051783;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;epidermal growth factor receptor signaling pathway#GO:0007173;cell surface receptor signaling pathway#GO:0007166;positive regulation of mitotic nuclear division#GO:0045840;regulation of mitotic nuclear division#GO:0007088 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 MONDO|Ensembl=ENSMODG00000010384.4|UniProtKB=F7AV84 F7AV84 CERKL PTHR12358:SF26 SPHINGOSINE KINASE CERAMIDE KINASE-LIKE PROTEIN lipid kinase activity#GO:0001727;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000005096.4|UniProtKB=F6ZEK4 F6ZEK4 PTGFRN PTHR12207:SF3 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN PROSTAGLANDIN F2 RECEPTOR NEGATIVE REGULATOR membrane#GO:0016020;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000001935.4|UniProtKB=F6W0L9 F6W0L9 PPP4R3B PTHR23318:SF18 ATP SYNTHASE GAMMA-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3B protein phosphatase regulator activity#GO:0019888;phosphatase activator activity#GO:0019211;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;enzyme activator activity#GO:0008047 biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;regulation of response to stress#GO:0080134;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA metabolic process#GO:0051052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of double-strand break repair#GO:2000779;regulation of cellular response to stress#GO:0080135;cellular response to stress#GO:0033554 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000009378.1|UniProtKB=F7CPZ0 F7CPZ0 FAM204A PTHR14386:SF2 PROTEIN FAM204A PROTEIN FAM204A MONDO|Ensembl=ENSMODG00000038398.1|UniProtKB=A0A5F8HHN0 A0A5F8HHN0 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000012754.2|UniProtKB=F6SJL4 F6SJL4 RPL7A PTHR23105:SF1 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN EL8 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000008268.4|UniProtKB=F6Z865 F6Z865 TTPA PTHR10174:SF225 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN transporter activity#GO:0005215;heterocyclic compound binding#GO:1901363;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;lipid carrier activity#GO:0005319;ion binding#GO:0043167;molecular carrier activity#GO:0140104;phosphatidylinositol bisphosphate binding#GO:1902936;lipid transfer activity#GO:0120013 localization#GO:0051179;vitamin transport#GO:0051180;establishment of localization#GO:0051234;vitamin E metabolic process#GO:0042360;metabolic process#GO:0008152;cellular process#GO:0009987;transport#GO:0006810 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;late endosome#GO:0005770;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000019901.4|UniProtKB=F6VQC8 F6VQC8 ARFGAP2 PTHR45686:SF10 ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000047978.1|UniProtKB=A0A5F8GHY6 A0A5F8GHY6 PTHR12560:SF6 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000005809.4|UniProtKB=F6XEG6 F6XEG6 PCYOX1L PTHR15944:SF2 FARNESYLCYSTEINE LYASE PRENYLCYSTEINE OXIDASE 1-LIKE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 lyase#PC00144;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000012771.4|UniProtKB=F6SIL8 F6SIL8 PTHR23402:SF15 PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED PYROGLUTAMYL-PEPTIDASE 1-LIKE PROTEIN catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000023099.3|UniProtKB=F7EXE4 F7EXE4 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010952.4|UniProtKB=F7BCM2 F7BCM2 CCSER2 PTHR22461:SF2 SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 2-RELATED SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule bundle formation#GO:0001578;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000015064.4|UniProtKB=F7FHK6 F7FHK6 BECN1 PTHR12768:SF4 BECLIN 1 BECLIN-1 phosphatidylinositol 3-kinase binding#GO:0043548;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein binding#GO:0005515 organelle assembly#GO:0070925;localization#GO:0051179;vacuole organization#GO:0007033;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;intracellular transport#GO:0046907;autophagy of mitochondrion#GO:0000422;cellular response to starvation#GO:0009267;transport#GO:0006810;vacuolar transport#GO:0007034;cellular response to nutrient levels#GO:0031669;establishment of localization#GO:0051234;mitophagy#GO:0000423;response to nutrient levels#GO:0031667;macroautophagy#GO:0016236;cellular response to stress#GO:0033554;cellular localization#GO:0051641;process utilizing autophagic mechanism#GO:0061919;cellular component organization#GO:0016043;response to stimulus#GO:0050896;late endosome to vacuole transport#GO:0045324;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;phagophore assembly site#GO:0000407;catalytic complex#GO:1902494;transferase complex#GO:1990234;phosphatidylinositol 3-kinase complex, class III#GO:0035032;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane#GO:0016020 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000018714.3|UniProtKB=F7FCC7 F7FCC7 KHDRBS2 PTHR11208:SF34 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 2 single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143;binding#GO:0005488;mRNA binding#GO:0003729 regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000015434.4|UniProtKB=F6SLT4 F6SLT4 NTN3 PTHR10574:SF292 NETRIN/LAMININ-RELATED NETRIN-3 plasma membrane bounded cell projection organization#GO:0120036;tissue development#GO:0009888;multicellular organismal process#GO:0032501;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;system development#GO:0048731;anatomical structure development#GO:0048856;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;axonogenesis#GO:0007409;neuron development#GO:0048666;dendrite development#GO:0016358;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix protein#PC00102 Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344;Axon guidance mediated by netrin#P00009>Netrin#P00357 MONDO|Ensembl=ENSMODG00000048225.1|UniProtKB=A0A5F8GYL6 A0A5F8GYL6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016939.4|UniProtKB=F6VMU4 F6VMU4 CHMP2B PTHR10476:SF72 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 2B multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;late endosome to vacuole transport#GO:0045324;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000022774.2|UniProtKB=H9H8V5 H9H8V5 LOC100017127 PTHR10722:SF0 60S RIBOSOMAL PROTEIN L19 LARGE RIBOSOMAL SUBUNIT PROTEIN EL19 binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;RNA binding#GO:0003723 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000021490.4|UniProtKB=F7G2T8 F7G2T8 MIB1 PTHR24202:SF53 E3 UBIQUITIN-PROTEIN LIGASE MIB2 E3 UBIQUITIN-PROTEIN LIGASE MIB1 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 signal transduction#GO:0007165;cellular process#GO:0009987;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219;establishment of localization#GO:0051234;import into cell#GO:0098657;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;signaling#GO:0023052;protein modification by small protein conjugation or removal#GO:0070647;localization#GO:0051179;cell communication#GO:0007154;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000048012.1|UniProtKB=A0A5F8G2B5 A0A5F8G2B5 PTHR21213:SF0 GEO09665P1-RELATED ZINC FINGER PROTEIN 706 MONDO|Ensembl=ENSMODG00000015738.4|UniProtKB=A0A5F8H6B5 A0A5F8H6B5 AGBL5 PTHR12756:SF12 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE-LIKE PROTEIN 5 carboxypeptidase activity#GO:0004180;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;protein binding#GO:0005515;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237;binding#GO:0005488;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cytoskeletal protein binding#GO:0008092;metalloexopeptidase activity#GO:0008235;tubulin binding#GO:0015631;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000022949.1|UniProtKB=F6PIS1 F6PIS1 C16orf54 PTHR36134:SF1 TRANSMEMBRANE PROTEIN C16ORF54 TRANSMEMBRANE PROTEIN C16ORF54 MONDO|Ensembl=ENSMODG00000027908.2|UniProtKB=K7E0A0 K7E0A0 CLBA1 PTHR16156:SF7 AFTIPHILIN A-RELATED CLATHRIN BINDING BOX OF AFTIPHILIN CONTAINING 1 clathrin binding#GO:0030276;binding#GO:0005488;protein binding#GO:0005515 intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;trans-Golgi network transport vesicle#GO:0030140;AP-1 adaptor complex#GO:0030121;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;trans-Golgi network transport vesicle membrane#GO:0012510;clathrin-coated vesicle#GO:0030136;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;coated membrane#GO:0048475;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;trans-Golgi network membrane#GO:0032588;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;vesicle coat#GO:0030120;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;clathrin-coated vesicle membrane#GO:0030665;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin vesicle coat#GO:0030125 MONDO|Ensembl=ENSMODG00000001344.4|UniProtKB=F7FWA1 F7FWA1 SLC6A3 PTHR11616:SF38 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT DOPAMINE TRANSPORTER monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810;amino acid transport#GO:0006865 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>DAT#P00065;Parkinson disease#P00049>DAT#P01228;Dopamine receptor mediated signaling pathway#P05912>DAT#P05962;Parkinson disease#P00049>DAT#G01547 MONDO|Ensembl=ENSMODG00000005714.3|UniProtKB=A0A5F8GM96 A0A5F8GM96 MTMR1 PTHR10807:SF40 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3-PHOSPHATE PHOSPHATASE MTMR1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;dephosphorylation#GO:0016311;lipid modification#GO:0030258 membrane#GO:0016020;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000001319.4|UniProtKB=A0A5F8HKC4 A0A5F8HKC4 ZNF518B PTHR24403:SF100 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 518B transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005949.4|UniProtKB=F6WFY1 F6WFY1 TMED10 PTHR22811:SF226 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 10 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 transport#GO:0006810;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;organelle organization#GO:0006996;macromolecule localization#GO:0033036;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;Golgi organization#GO:0007030;cellular component organization#GO:0016043 endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;cytoplasm#GO:0005737;endomembrane system#GO:0012505;COPI-coated vesicle#GO:0030137;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane traffic protein#PC00150;vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000008504.4|UniProtKB=F7FTF7 F7FTF7 TARBP1 PTHR12029:SF11 RNA METHYLTRANSFERASE TRNA (GUANOSINE(18)-2'-O)-METHYLTRANSFERASE TARBP1 catalytic activity, acting on a tRNA#GO:0140101;tRNA (guanine) methyltransferase activity#GO:0016423;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000009372.3|UniProtKB=F7CQ39 F7CQ39 PTCD3 PTHR16276:SF1 PENTATRICOPEPTIDE REPEAT DOMAIN-CONTAINING PROTEIN 3 SMALL RIBOSOMAL SUBUNIT PROTEIN MS39 rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;binding#GO:0005488;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723 biosynthetic process#GO:0009058;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000018964.4|UniProtKB=F7G057 F7G057 POLR1C PTHR11800:SF13 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1 nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;RNA polymerase III complex#GO:0005666;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000012960.3|UniProtKB=F7DC74 F7DC74 PSAT1 PTHR43247:SF1 PHOSPHOSERINE AMINOTRANSFERASE PHOSPHOSERINE AMINOTRANSFERASE heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 proteinogenic amino acid biosynthetic process#GO:0170038;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transaminase#PC00216 Vitamin B6 metabolism#P02787>Phosphoserine transaminase#P03227;Serine glycine biosynthesis#P02776>Phosphoserine aminotransferase#P03157;Pyridoxal-5-phosphate biosynthesis#P02759>Phosphohydroxythreonine aminotransferase#P03058 MONDO|Ensembl=ENSMODG00000001538.4|UniProtKB=A0A5F8GVB3 A0A5F8GVB3 PTHR24376:SF210 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 721-RELATED gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000003889.4|UniProtKB=F7D8N1 F7D8N1 TRAPPC2L PTHR12403:SF11 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-LIKE PROTEIN cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000008205.3|UniProtKB=F7DJ33 F7DJ33 CCDC42 PTHR21683:SF8 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 42 cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;male gamete generation#GO:0048232;cellular process#GO:0009987;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;spermatid development#GO:0007286;spermatid differentiation#GO:0048515;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;cell development#GO:0048468;cell differentiation#GO:0030154;gamete generation#GO:0007276;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000001870.4|UniProtKB=F6S6G5 F6S6G5 PM20D1 PTHR45962:SF4 N-FATTY-ACYL-AMINO ACID SYNTHASE/HYDROLASE PM20D1 N-FATTY-ACYL-AMINO ACID SYNTHASE_HYDROLASE PM20D1 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 homeostatic process#GO:0042592;multicellular organismal process#GO:0032501;cellular process#GO:0009987;primary metabolic process#GO:0044238;multicellular organismal-level homeostasis#GO:0048871;lipid metabolic process#GO:0006629;adaptive thermogenesis#GO:1990845;temperature homeostasis#GO:0001659;metabolic process#GO:0008152 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000009267.4|UniProtKB=F7DAK5 F7DAK5 MPP1 PTHR23122:SF37 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK 55 KDA ERYTHROCYTE MEMBRANE PROTEIN signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of transport#GO:0051049;intracellular protein localization#GO:0008104;regulation of localization#GO:0032879;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;macromolecule localization#GO:0033036;regulation of secretion#GO:0051046;localization#GO:0051179;regulation of secretion by cell#GO:1903530;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of neurotransmitter secretion#GO:0046928;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000012932.4|UniProtKB=F7G1U7 F7G1U7 GNA14 PTHR10218:SF213 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-14 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;regulation of biological quality#GO:0065008;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;action potential#GO:0001508;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;G protein-coupled dopamine receptor signaling pathway#GO:0007212;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221 side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 heterotrimeric G-protein#PC00117;G-protein#PC00020 PI3 kinase pathway#P00048>Galpha#P01199;Wnt signaling pathway#P00057>Galpha#P01451;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Endothelin signaling pathway#P00019>Gq#P00586;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073 MONDO|Ensembl=ENSMODG00000011247.4|UniProtKB=F6RLX0 F6RLX0 C1QL1 PTHR22923:SF64 CEREBELLIN-RELATED C1Q-RELATED FACTOR cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000044002.1|UniProtKB=F7GKU7 F7GKU7 LOC100017021 PTHR48018:SF168 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020948.4|UniProtKB=H9H9J5 H9H9J5 PTHR11783:SF9 SULFOTRANSFERASE SULT SULFOTRANSFERASE 2B1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000001353.4|UniProtKB=F7FW54 F7FW54 NDRG3 PTHR11034:SF20 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG3 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000021059.3|UniProtKB=F6VIW3 F6VIW3 CRYZL1 PTHR44461:SF1 QUINONE OXIDOREDUCTASE-LIKE PROTEIN 1 FERRY ENDOSOMAL RAB5 EFFECTOR COMPLEX SUBUNIT 4 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000002257.4|UniProtKB=A0A5F8GTY4 A0A5F8GTY4 PTHR33820:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 17 COILED-COIL DOMAIN-CONTAINING PROTEIN 17 MONDO|Ensembl=ENSMODG00000003620.4|UniProtKB=A0A5F8HC04 A0A5F8HC04 VLDLR PTHR24270:SF16 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED VERY LOW-DENSITY LIPOPROTEIN RECEPTOR binding#GO:0005488;protein binding#GO:0005515 central nervous system development#GO:0007417;endocytosis#GO:0006897;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;localization#GO:0051179;anatomical structure development#GO:0048856;cellular process#GO:0009987;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;developmental process#GO:0032502;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;multicellular organism development#GO:0007275;establishment of localization#GO:0051234;import into cell#GO:0098657 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transfer/carrier protein#PC00219;apolipoprotein#PC00052 MONDO|Ensembl=ENSMODG00000020093.3|UniProtKB=F7ESP5 F7ESP5 RFESD PTHR21496:SF0 FERREDOXIN-RELATED RIESKE DOMAIN-CONTAINING PROTEIN small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000008417.4|UniProtKB=F7B7Q4 F7B7Q4 ARID4B PTHR13964:SF24 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 4B transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000044984.1|UniProtKB=A0A5F8GK30 A0A5F8GK30 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000021365.4|UniProtKB=H9H804 H9H804 MRPL37 PTHR15889:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN L37 LARGE RIBOSOMAL SUBUNIT PROTEIN ML37 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000007723.4|UniProtKB=A0A5F8G4Y9 A0A5F8G4Y9 TMPO PTHR12019:SF24 LAMINA-ASSOCIATED POLYPEPTIDE THYMOPOIETIN LAMINA-ASSOCIATED POLYPEPTIDE 2, ISOFORM ALPHA intercellular signal molecule#PC00207;peptide hormone#PC00179 MONDO|Ensembl=ENSMODG00000016835.3|UniProtKB=F6R247 F6R247 GID8 PTHR12864:SF85 RAN BINDING PROTEIN 9-RELATED GLUCOSE-INDUCED DEGRADATION PROTEIN 8 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein metabolic process#GO:0019538;positive regulation of signaling#GO:0023056;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of canonical Wnt signaling pathway#GO:0090263;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828 ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013425.3|UniProtKB=F7CMZ5 F7CMZ5 PPIC PTHR11071:SF11 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE C cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000008109.2|UniProtKB=F7G5J7 F7G5J7 CLEC3A PTHR22799:SF2 TETRANECTIN-RELATED C-TYPE LECTIN DOMAIN FAMILY 3 MEMBER A ossification#GO:0001503;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000009090.4|UniProtKB=A0A5F8HCX1 A0A5F8HCX1 PTHR31159:SF1 COMM DOMAIN-CONTAINING PROTEIN 3 COMM DOMAIN-CONTAINING PROTEIN 3 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000021100.2|UniProtKB=F6UI20 F6UI20 CXorf38 PTHR35083:SF1 RGD1565685 PROTEIN RGD1565685 PROTEIN MONDO|Ensembl=ENSMODG00000011978.4|UniProtKB=F7B9T8 F7B9T8 SLC66A2 PTHR14856:SF10 PQ-LOOP REPEAT-CONTAINING PROTEIN 1-LIKE PROTEIN SOLUTE CARRIER FAMILY 66 MEMBER 2 macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lipid transport#GO:0006869;vesicle-mediated transport#GO:0016192;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;endosomal transport#GO:0016197;regulation of membrane lipid distribution#GO:0097035;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cytosolic transport#GO:0016482;lipid localization#GO:0010876;localization#GO:0051179;cellular localization#GO:0051641;regulation of biological quality#GO:0065008 trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000018566.3|UniProtKB=F7FRR4 F7FRR4 TPP1 PTHR14218:SF41 PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2 TRIPEPTIDYL-PEPTIDASE 1 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 developmental process#GO:0032502;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;protein catabolic process#GO:0030163;protein catabolic process in the vacuole#GO:0007039;proteolysis#GO:0006508;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;primary metabolic process#GO:0044238;catabolic process#GO:0009056;central nervous system development#GO:0007417 lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000023736.2|UniProtKB=F6X8T7 F6X8T7 PTHR21324:SF11 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED DNA DAMAGE-REGULATED AUTOPHAGY MODULATOR PROTEIN 1 regulation of metabolic process#GO:0019222;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of catabolic process#GO:0009894;biological regulation#GO:0065007 lysosome#GO:0005764;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006736.4|UniProtKB=F7CDE4 F7CDE4 MMP23B PTHR10201:SF7 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-23 metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;extracellular structure organization#GO:0043062;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;cellular process#GO:0009987;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 MONDO|Ensembl=ENSMODG00000012545.4|UniProtKB=F6PM24 F6PM24 ATP6V0A2 PTHR11629:SF22 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A 2 proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;binding#GO:0005488;enzyme binding#GO:0019899;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324 transmembrane transport#GO:0055085;cellular component disassembly#GO:0022411;monoatomic ion transport#GO:0006811;process utilizing autophagic mechanism#GO:0061919;regulation of biological quality#GO:0065008;intracellular monoatomic ion homeostasis#GO:0006873;cellular component organization#GO:0016043;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;monoatomic ion homeostasis#GO:0050801;autophagy#GO:0006914;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;monoatomic cation transport#GO:0006812;localization#GO:0051179;catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;homeostatic process#GO:0042592;autophagosome maturation#GO:0097352;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;proton transmembrane transport#GO:1902600;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;macroautophagy#GO:0016236 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;proton-transporting two-sector ATPase complex#GO:0016469;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000004066.4|UniProtKB=F6VWE8 F6VWE8 CNOT3 PTHR23326:SF34 CCR4 NOT-RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3 regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;CCR4-NOT complex#GO:0030014 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000008893.4|UniProtKB=F7BRG5 F7BRG5 ZCRB1 PTHR46259:SF1 ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000015959.4|UniProtKB=F7FRF0 F7FRF0 METTL21A PTHR14614:SF14 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN N-LYSINE METHYLTRANSFERASE METTL21A lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000028817.1|UniProtKB=K7E3C1 K7E3C1 LOC100018892 PTHR26450:SF141 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012527.5|UniProtKB=F6PZU3 F6PZU3 NLRP12 PTHR45690:SF24 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NLR FAMILY PYRIN DOMAIN CONTAINING 12 regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000049990.1|UniProtKB=A0A5F8H527 A0A5F8H527 PTHR10502:SF26 ANNEXIN ANNEXIN A5 ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phospholipid binding#GO:0005543;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289 nucleus#GO:0005634;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 calcium-binding protein#PC00060 Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#G06684;Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#G06897;Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#P06814 MONDO|Ensembl=ENSMODG00000042880.1|UniProtKB=A0A5F8GQY6 A0A5F8GQY6 PTHR26450:SF76 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51B5 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018567.4|UniProtKB=F7FRQ1 F7FRQ1 PTHR12482:SF11 LIPASE ROG1-RELATED-RELATED ESTERASE_LIPASE_THIOESTERASE DOMAIN-CONTAINING PROTEIN lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 MONDO|Ensembl=ENSMODG00000017011.2|UniProtKB=F6QF22 F6QF22 ARFRP1 PTHR45909:SF1 ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1 ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;protein localization to Golgi apparatus#GO:0034067;protein localization to cell periphery#GO:1990778;intracellular transport#GO:0046907;Golgi to plasma membrane protein transport#GO:0043001;Golgi to plasma membrane transport#GO:0006893;protein localization to organelle#GO:0033365;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000014731.5|UniProtKB=F6ZCQ5 F6ZCQ5 KBTBD3 PTHR24412:SF418 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017552.4|UniProtKB=F7E0Y0 F7E0Y0 PRKD1 PTHR22968:SF9 PROTEIN KINASE C, MU SERINE_THREONINE-PROTEIN KINASE D1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CCKR signaling map#P06959>PRKD1#P07103;EGF receptor signaling pathway#P00018>PKC#P00565;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219 MONDO|Ensembl=ENSMODG00000010658.4|UniProtKB=F7FZN4 F7FZN4 TSR1 PTHR12858:SF1 RIBOSOME BIOGENESIS PROTEIN PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;nucleic acid binding#GO:0003676;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;hydrolase activity#GO:0016787;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000009241.4|UniProtKB=A0A5F8HHT2 A0A5F8HHT2 CAPN9 PTHR10183:SF385 CALPAIN CALPAIN-9 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protease#PC00190;cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 MONDO|Ensembl=ENSMODG00000036563.1|UniProtKB=A0A5F8GAA2 A0A5F8GAA2 PTHR48002:SF99 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003266.3|UniProtKB=F6SJY5 F6SJY5 CHMP4A PTHR22761:SF14 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 4A late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;membrane assembly#GO:0071709;cellular localization#GO:0051641;localization#GO:0051179;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular component assembly#GO:0022607;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;establishment of localization in cell#GO:0051649;nucleus organization#GO:0006997;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;nuclear envelope organization#GO:0006998;vesicle budding from membrane#GO:0006900;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034 endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;side of membrane#GO:0098552;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;organelle envelope#GO:0031967;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic side of membrane#GO:0098562;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;nucleus#GO:0005634;cell periphery#GO:0071944;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;plasma membrane#GO:0005886 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000047616.1|UniProtKB=A0A5F8H2Q5 A0A5F8H2Q5 SLC35C2 PTHR11132:SF238 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER H1 active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;nucleotide-sugar transmembrane transport#GO:0015780;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;cis-Golgi network#GO:0005801;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000009478.4|UniProtKB=F7FNK2 F7FNK2 METTL15 PTHR11265:SF0 S-ADENOSYL-METHYLTRANSFERASE MRAW 12S RRNA N(4)-CYTIDINE METHYLTRANSFERASE METTL15 catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a rRNA#GO:0140102 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;rRNA base methylation#GO:0070475;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA methylation#GO:0031167;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000041262.1|UniProtKB=A0A5F8GM89 A0A5F8GM89 PTHR23262:SF248 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-6 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000015680.4|UniProtKB=F6QUG0 F6QUG0 MLF1 PTHR13105:SF22 MYELOID LEUKEMIA FACTOR MYELOID LEUKEMIA FACTOR 1 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000018923.4|UniProtKB=F7GJW1 F7GJW1 CDC5L PTHR45885:SF6 CELL DIVISION CYCLE 5-LIKE PROTEIN CELL DIVISION CYCLE 5-LIKE PROTEIN transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of transcription by RNA polymerase II#GO:0006357;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions#GO:0000375;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of DNA-templated transcription#GO:0006355;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889 Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 MONDO|Ensembl=ENSMODG00000004761.4|UniProtKB=F6X146 F6X146 PTHR21686:SF12 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000000346.4|UniProtKB=A0A5F8HF40 A0A5F8HF40 SEC24C PTHR13803:SF5 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24C cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;SNARE binding#GO:0000149;zinc ion binding#GO:0008270 cellular component organization#GO:0016043;COPII-coated vesicle budding#GO:0090114;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900 protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;cytoplasm#GO:0005737;vesicle coat#GO:0030120;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;ER to Golgi transport vesicle membrane#GO:0012507;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000011693.4|UniProtKB=H9H6I4 H9H6I4 LOC100011973 PTHR19306:SF6 STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stress#GO:0033554;recombinational repair#GO:0000725 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;nucleus#GO:0005634;site of double-strand break#GO:0035861;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000019705.3|UniProtKB=F6TC58 F6TC58 PTHR48001:SF135 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1N2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028470.2|UniProtKB=A0A5F8GHD7 A0A5F8GHD7 PTHR34833:SF1 GENE, 17359-RELATED PROTEIN SPMIP2 MONDO|Ensembl=ENSMODG00000041104.1|UniProtKB=A0A5F8H283 A0A5F8H283 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000022840.2|UniProtKB=H9H6J0 H9H6J0 RLIM PTHR45931:SF30 SI:CH211-59O9.10 RING-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000019463.4|UniProtKB=A0A5F8H2A3 A0A5F8H2A3 FST PTHR10913:SF6 FOLLISTATIN-RELATED FOLLISTATIN protein-containing complex binding#GO:0044877;activin binding#GO:0048185;binding#GO:0005488 regulation of cell communication#GO:0010646;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Gonadotropin-releasing hormone receptor pathway#P06664>Follistatin#G06671;Gonadotropin-releasing hormone receptor pathway#P06664>Follistatin#P06835;Gonadotropin-releasing hormone receptor pathway#P06664>Follistatin#G06885 MONDO|Ensembl=ENSMODG00000002738.3|UniProtKB=F6Z773 F6Z773 FEZF2 PTHR24393:SF135 ZINC FINGER PROTEIN FEZ FAMILY ZINC FINGER PROTEIN ERM sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025601.3|UniProtKB=F6QC79 F6QC79 PTHR48122:SF1 CENTROMERE PROTEIN H CENTROMERE PROTEIN H binding#GO:0005488 microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;microtubule cytoskeleton organization#GO:0000226;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;organelle organization#GO:0006996;cell cycle#GO:0007049 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694;membraneless organelle#GO:0043228;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779 MONDO|Ensembl=ENSMODG00000011012.2|UniProtKB=F7A0H0 F7A0H0 OR52E1 PTHR26450:SF3 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040687.1|UniProtKB=A0A5F8GQ56 A0A5F8GQ56 PTHR26452:SF930 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000018077.4|UniProtKB=F7EVA4 F7EVA4 NOP2 PTHR22807:SF30 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a rRNA#GO:0140102 rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;rRNA methylation#GO:0031167;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;rRNA base methylation#GO:0070475;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA modification#GO:0000154;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000005398.3|UniProtKB=F7G6E7 F7G6E7 OTOR PTHR47146:SF1 OTORAPLIN OTORAPLIN skeletal system morphogenesis#GO:0048705;cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;tissue development#GO:0009888;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;animal organ development#GO:0048513;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;cartilage development#GO:0051216;connective tissue development#GO:0061448;system development#GO:0048731 MONDO|Ensembl=ENSMODG00000038041.1|UniProtKB=A0A5F8GT22 A0A5F8GT22 LOC103097786 PTHR26453:SF33 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015932.4|UniProtKB=F6Z395 F6Z395 PTK2B PTHR24418:SF94 TYROSINE-PROTEIN KINASE PROTEIN-TYROSINE KINASE 2-BETA transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cellular process#GO:0009987;positive regulation of cell migration#GO:0030335;ERBB signaling pathway#GO:0038127;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of cell adhesion#GO:0030155;cell surface receptor signaling pathway#GO:0007166;regulation of cell migration#GO:0030334;positive regulation of locomotion#GO:0040017 plasma membrane#GO:0005886;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;anchoring junction#GO:0070161;cell junction#GO:0030054 non-receptor tyrosine protein kinase#PC00168 Integrin signalling pathway#P00034>FAK#P00932;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PYK2#P00852;Gonadotropin-releasing hormone receptor pathway#P06664>Pyk2#P06730;CCKR signaling map#P06959>FAK2#P07218 MONDO|Ensembl=ENSMODG00000008170.4|UniProtKB=A0A5F8GCY5 A0A5F8GCY5 PTHR48071:SF15 SRCR DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR FAMILY 12 SUBFAMILY J MEMBER 2 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000015766.4|UniProtKB=F6ZT09 F6ZT09 VN2R653 PTHR24061:SF1 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 2-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016388.4|UniProtKB=F7E9F9 F7E9F9 CCDC71L PTHR14484:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 71 COILED-COIL DOMAIN-CONTAINING PROTEIN 71L MONDO|Ensembl=ENSMODG00000046180.1|UniProtKB=A0A5F8GB51 A0A5F8GB51 FBXL22 PTHR16134:SF1 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX AND LEUCINE-RICH PROTEIN 22 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 response to light stimulus#GO:0009416;response to stimulus#GO:0050896;catabolic process#GO:0009056;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;response to radiation#GO:0009314;cellular process#GO:0009987;regulation of circadian rhythm#GO:0042752;ubiquitin-dependent protein catabolic process#GO:0006511;response to external stimulus#GO:0009605;macromolecule metabolic process#GO:0043170;photoperiodism#GO:0009648;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 cytosol#GO:0005829;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000023891.3|UniProtKB=A0A5F8GX90 A0A5F8GX90 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 immune system process#GO:0002376;immune effector process#GO:0002252;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000042676.1|UniProtKB=A0A5F8GVW6 A0A5F8GVW6 PTHR37871:SF1 PROLINE-RICH PROTEIN 22 PROLINE-RICH PROTEIN 22 MONDO|Ensembl=ENSMODG00000050649.1|UniProtKB=A0A5F8GDY3 A0A5F8GDY3 PTHR10424:SF82 VIRAL ENVELOPE PROTEIN ENVELOPE POLYPROTEIN cellular process#GO:0009987;muscle cell differentiation#GO:0042692;myoblast fusion#GO:0007520;muscle structure development#GO:0061061;cell differentiation#GO:0030154;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;cell-cell fusion#GO:0140253;striated muscle cell differentiation#GO:0051146;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;syncytium formation by cell-cell fusion#GO:0000768 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009582.4|UniProtKB=F7AWE8 F7AWE8 LGI3 PTHR24367:SF10 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH REPEAT LGI FAMILY MEMBER 3 regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of secretion#GO:0051046 cell junction#GO:0030054;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;presynapse#GO:0098793;secretory vesicle#GO:0099503;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708 MONDO|Ensembl=ENSMODG00000024126.2|UniProtKB=F6Y0Q4 F6Y0Q4 KRTAP3-1 PTHR23260:SF3 KERATIN ASSOCIATED PROTEIN 3-3-RELATED KERATIN-ASSOCIATED PROTEIN 3-1 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000014741.4|UniProtKB=F6ZC29 F6ZC29 ODAD4 PTHR23040:SF1 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 4 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 4 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000035078.2|UniProtKB=F6QPM9 F6QPM9 STYXL1 PTHR46659:SF1 SERINE/THREONINE/TYROSINE-INTERACTING-LIKE PROTEIN 1 SERINE_THREONINE_TYROSINE-INTERACTING-LIKE PROTEIN 1 phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase binding#GO:0019903;phosphatase inhibitor activity#GO:0019212 regulation of intracellular signal transduction#GO:1902531;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;positive regulation of signal transduction#GO:0009967;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of cellular component organization#GO:0051128;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of cellular component biogenesis#GO:0044087;positive regulation of apoptotic signaling pathway#GO:2001235;negative regulation of cellular process#GO:0048523;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;positive regulation of cellular process#GO:0048522;regulation of organelle assembly#GO:1902115;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000009546.4|UniProtKB=F7BK12 F7BK12 EVX2 PTHR46294:SF1 SEGMENTATION PROTEIN EVEN-SKIPPED HOMEOBOX EVEN-SKIPPED HOMOLOG PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000039004.1|UniProtKB=A0A5F8GFS8 A0A5F8GFS8 PTHR48439:SF1 HEMIMETHYLATED DNA-BINDING DOMAIN-CONTAINING PROTEIN HEMIMETHYLATED DNA-BINDING DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000025647.3|UniProtKB=F6XEA7 F6XEA7 PTHR24377:SF980 IP01015P-RELATED ZINC FINGER PROTEIN 420 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010362.4|UniProtKB=A0A5F8HHU2 A0A5F8HHU2 ARHGAP26 PTHR12552:SF4 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN 26 enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174;Integrin signalling pathway#P00034>GRAF#P00926 MONDO|Ensembl=ENSMODG00000004133.4|UniProtKB=F6UVJ1 F6UVJ1 RAD21 PTHR12585:SF20 SCC1 / RAD21 FAMILY MEMBER DOUBLE-STRAND-BREAK REPAIR PROTEIN RAD21 HOMOLOG chromatin binding#GO:0003682;binding#GO:0005488 response to stimulus#GO:0050896;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;sister chromatid cohesion#GO:0007062;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974 chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cohesin complex#GO:0008278;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000014772.4|UniProtKB=F7G763 F7G763 MTRF1 PTHR43804:SF1 LD18447P PEPTIDE CHAIN RELEASE FACTOR 1, MITOCHONDRIAL cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;translational termination#GO:0006415;translation#GO:0006412;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;protein-containing complex disassembly#GO:0032984;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 translational protein#PC00263;translation factor#PC00223;translation release factor#PC00225 MONDO|Ensembl=ENSMODG00000041855.1|UniProtKB=A0A5F8HH22 A0A5F8HH22 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009276.3|UniProtKB=H9H6B2 H9H6B2 C5H12orf57 PTHR13463:SF3 PROTEIN C10 PROTEIN C10 multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;post-embryonic development#GO:0009791 MONDO|Ensembl=ENSMODG00000039316.1|UniProtKB=F6Q3N3 F6Q3N3 PTHR23267:SF313 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 5-2 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000001715.4|UniProtKB=A0A5F8GG21 A0A5F8GG21 CDHR1 PTHR24028:SF263 CADHERIN-87A CADHERIN-RELATED FAMILY MEMBER 1 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000020566.4|UniProtKB=F7APL6 F7APL6 APBB2 PTHR14058:SF11 AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B AMYLOID BETA PRECURSOR PROTEIN BINDING FAMILY B MEMBER 2 peptide binding#GO:0042277;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 Alzheimer disease-presenilin pathway#P00004>Fe65#P00126 MONDO|Ensembl=ENSMODG00000017880.3|UniProtKB=F6YHQ9 F6YHQ9 ADPRS PTHR16222:SF24 ADP-RIBOSYLGLYCOHYDROLASE ADP-RIBOSYLHYDROLASE ARH3 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;metabolic process#GO:0008152;cellular response to chemical stress#GO:0062197;macromolecule metabolic process#GO:0043170;response to oxidative stress#GO:0006979;response to reactive oxygen species#GO:0000302 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000013364.5|UniProtKB=A0A5F8GEK6 A0A5F8GEK6 AMFR PTHR15067:SF5 E3 UBIQUITIN-PROTEIN LIGASE RNF8 E3 UBIQUITIN-PROTEIN LIGASE AMFR acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cell communication#GO:0007154;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;intracellular signal transduction#GO:0035556;endoplasmic reticulum unfolded protein response#GO:0030968;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;protein K48-linked ubiquitination#GO:0070936;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;response to unfolded protein#GO:0006986;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000019455.5|UniProtKB=F6RXF1 F6RXF1 NOL4L PTHR12449:SF19 DEATH DOMAIN-CONTAINING PROTEIN NUCLEOLAR PROTEIN 4-LIKE MONDO|Ensembl=ENSMODG00000010956.4|UniProtKB=F7BCC7 F7BCC7 LOC100020131 PTHR43570:SF15 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE, DIMERIC NADP-PREFERRING oxidoreductase activity#GO:0016491;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081 membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 MONDO|Ensembl=ENSMODG00000050431.1|UniProtKB=A0A5F8GF85 A0A5F8GF85 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000039154.1|UniProtKB=F7CQB3 F7CQB3 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000005872.3|UniProtKB=F7D222 F7D222 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004411.4|UniProtKB=F6SV50 F6SV50 ACVR1C PTHR23255:SF58 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-1C molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;activin binding#GO:0048185 signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;activin receptor signaling pathway#GO:0032924;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731 protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;signaling receptor complex#GO:0043235;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796 serine/threonine protein kinase receptor#PC00205 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283 MONDO|Ensembl=ENSMODG00000001797.4|UniProtKB=F6WI67 F6WI67 STRIP1 PTHR13239:SF7 PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2 STRIATIN-INTERACTING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of hippo signaling#GO:0035331;negative regulation of intracellular signal transduction#GO:1902532;cellular process#GO:0009987;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000028390.2|UniProtKB=K7E4J7 K7E4J7 CST6 PTHR47033:SF1 CYSTATIN-M CYSTATIN-M enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 anatomical structure development#GO:0048856;tissue development#GO:0009888;epidermis development#GO:0008544;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000011215.3|UniProtKB=A0A5F8HCR9 A0A5F8HCR9 PTHR45931:SF2 SI:CH211-59O9.10 E3 UBIQUITIN-PROTEIN LIGASE RNF6 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of RNA metabolic process#GO:0051254;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;macromolecule modification#GO:0043412;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-translational protein modification#GO:0043687;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000049550.1|UniProtKB=A0A5F8GCF4 A0A5F8GCF4 OTUB2 PTHR12931:SF3 UBIQUITIN THIOLESTERASE PROTEIN OTUB UBIQUITIN THIOESTERASE OTUB2 hydrolase activity#GO:0016787;protein binding#GO:0005515;deubiquitinase activity#GO:0101005;binding#GO:0005488;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;ubiquitin binding#GO:0043130;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000004697.4|UniProtKB=A0A5F8GMA6 A0A5F8GMA6 PLCB4 PTHR10336:SF36 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4 hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;hydrolase activity#GO:0016787 metabolic process#GO:0008152;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;signal transduction#GO:0007165;glycerophospholipid metabolic process#GO:0006650;monoatomic cation transmembrane transport#GO:0098655;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;phosphorus metabolic process#GO:0006793;calcium ion transmembrane transport#GO:0070588;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;signaling#GO:0023052;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;transport#GO:0006810;establishment of localization#GO:0051234;organophosphate metabolic process#GO:0019637;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;phospholipid metabolic process#GO:0006644 lipase#PC00143;metabolite interconversion enzyme#PC00262;phospholipase#PC00186;hydrolase#PC00121 Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Metabotropic glutamate receptor group I pathway#P00041>PLC#P01053;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Endothelin signaling pathway#P00019>PLCbeta#P00591;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PLC#P01068;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Wnt signaling pathway#P00057>Phospholipase C#P01443;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874 MONDO|Ensembl=ENSMODG00000005539.4|UniProtKB=F7FHW3 F7FHW3 UGCG PTHR12726:SF0 CERAMIDE GLUCOSYLTRANSFERASE CERAMIDE GLUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758 ceramide metabolic process#GO:0006672;glycolipid biosynthetic process#GO:0009247;glycosphingolipid biosynthetic process#GO:0006688;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cellular anatomical structure#GO:0110165;membrane#GO:0016020 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000048890.1|UniProtKB=A0A5F8GTP3 A0A5F8GTP3 NIPSNAP1 PTHR21017:SF11 NIPSNAP-RELATED PROTEIN NIPSNAP HOMOLOG 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 autophagy#GO:0006914;cellular process#GO:0009987;macroautophagy#GO:0016236;catabolic process#GO:0009056;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;process utilizing autophagic mechanism#GO:0061919;mitophagy#GO:0000423 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000020194.3|UniProtKB=F7G8B5 F7G8B5 PTHR24100:SF149 BUTYROPHILIN BG ANTIGEN 1, MHCB REGION-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;regulation of immune response#GO:0050776;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000005337.4|UniProtKB=F7CHT9 F7CHT9 PSMD14 PTHR10410:SF5 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED UBIQUITIN C-TERMINAL HYDROLASE PSMD14 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;deubiquitinase activity#GO:0101005 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;proteasome regulatory particle, lid subcomplex#GO:0008541;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;proteasome complex#GO:0000502;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translation factor#PC00223;translation initiation factor#PC00224 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 MONDO|Ensembl=ENSMODG00000004062.4|UniProtKB=F7BIW7 F7BIW7 SLC9C2 PTHR10110:SF91 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 11 potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;import into cell#GO:0098657;establishment of localization#GO:0051234;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000011819.4|UniProtKB=F7CBB5 F7CBB5 AAK1 PTHR47907:SF9 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE MONDO|Ensembl=ENSMODG00000045917.1|UniProtKB=A0A5F8HG99 A0A5F8HG99 PTHR46880:SF14 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE KIAA1586 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659 cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein sumoylation#GO:0016925;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 MONDO|Ensembl=ENSMODG00000018592.4|UniProtKB=F7FCU2 F7FCU2 CNGA4 PTHR45638:SF2 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL ALPHA-4 heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;guanyl ribonucleotide binding#GO:0032561;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;nucleotide binding#GO:0000166;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;multicellular organismal process#GO:0032501;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;system process#GO:0003008;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000006150.4|UniProtKB=F7BSM7 F7BSM7 E2F4 PTHR12081:SF42 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000009368.4|UniProtKB=A0A5F8G8H6 A0A5F8G8H6 PTHR14167:SF31 SH3 DOMAIN-CONTAINING NOSTRIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000003938.4|UniProtKB=F7G9U7 F7G9U7 RNF4 PTHR23041:SF82 RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF4 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;response to stress#GO:0006950;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;DNA repair#GO:0006281;DNA damage response#GO:0006974;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;nucleobase-containing compound metabolic process#GO:0006139;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000000725.3|UniProtKB=F6W611 F6W611 CIMIP4 PTHR31702:SF2 TESTIS-EXPRESSED PROTEIN 33 CILIARY MICROTUBULE INNER PROTEIN 4 MONDO|Ensembl=ENSMODG00000015780.4|UniProtKB=F6Z4E0 F6Z4E0 TNF PTHR11471:SF23 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;programmed cell death#GO:0012501;regulation of extrinsic apoptotic signaling pathway#GO:2001236;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cell death#GO:0008219;tumor necrosis factor-mediated signaling pathway#GO:0033209;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to tumor necrosis factor#GO:0034612;regulation of canonical NF-kappaB signal transduction#GO:0043122;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;apoptotic signaling pathway#GO:0097190;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;regulation of signaling#GO:0023051;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Apoptosis signaling pathway#P00006>TNF#P00259 MONDO|Ensembl=ENSMODG00000015084.3|UniProtKB=A0A5F8GB17 A0A5F8GB17 MCOLN1 PTHR12127:SF6 MUCOLIPIN MUCOLIPIN-1 monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857 cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;membrane#GO:0016020;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000047093.1|UniProtKB=A0A5F8HAU9 A0A5F8HAU9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000001533.4|UniProtKB=F7EMV4 F7EMV4 PHF20 PTHR15856:SF27 PHD FINGER PROTEIN 20-RELATED PHD FINGER PROTEIN 20 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;intracellular organelle lumen#GO:0070013;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;NSL complex#GO:0044545;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000017674.3|UniProtKB=F7GFX6 F7GFX6 PTHR15705:SF1 MCG7194, ISOFORM CRA_A RIKEN CDNA 9330159F19 GENE MONDO|Ensembl=ENSMODG00000025602.2|UniProtKB=F6QC63 F6QC63 PTHR17102:SF4 NEURONAL REGENERATION-RELATED PROTEIN NEURONAL REGENERATION-RELATED PROTEIN regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;system development#GO:0048731;anatomical structure development#GO:0048856;plasma membrane bounded cell projection organization#GO:0120036;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of neuron differentiation#GO:0045664;axon development#GO:0061564;response to wounding#GO:0009611;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;cell development#GO:0048468;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;cellular response to stress#GO:0033554;animal gross anatomical part developmental process#GO:0160108;regeneration#GO:0031099;nervous system development#GO:0007399;cellular process#GO:0009987;response to stress#GO:0006950;neuron projection development#GO:0031175;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182 MONDO|Ensembl=ENSMODG00000019498.4|UniProtKB=F6VUT5 F6VUT5 VPS33B PTHR11679:SF92 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33B macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031 lytic vacuole#GO:0000323;vesicle tethering complex#GO:0099023;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000015322.5|UniProtKB=F6XXI9 F6XXI9 RETREG2 PTHR20952:SF4 ADP-RIBOSYLATION-LIKE FACTOR 6-INTERACTING PROTEIN RETICULOPHAGY REGULATOR 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 process utilizing autophagic mechanism#GO:0061919;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;endoplasmic reticulum tubular network organization#GO:0071786;catabolic process#GO:0009056;metabolic process#GO:0008152;endoplasmic reticulum membrane organization#GO:0090158;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;reticulophagy#GO:0061709;autophagy#GO:0006914;cellular process#GO:0009987;cellular component assembly#GO:0022607;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;macroautophagy#GO:0016236 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum tubular network#GO:0071782;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000012132.2|UniProtKB=F6Y5Y1 F6Y5Y1 QRFP PTHR36476:SF1 OREXIGENIC NEUROPEPTIDE QRFP OREXIGENIC NEUROPEPTIDE QRFP binding#GO:0005488;signaling receptor binding#GO:0005102;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;neuropeptide hormone activity#GO:0005184 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;regulation of multicellular organismal process#GO:0051239;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 MONDO|Ensembl=ENSMODG00000011041.4|UniProtKB=F7F443 F7F443 MBD2 PTHR12396:SF62 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG BINDING DOMAIN PROTEIN 2 negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of gene expression, epigenetic#GO:0045814;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;cellular component organization or biogenesis#GO:0071840;constitutive heterochromatin formation#GO:0140719;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000015705.4|UniProtKB=F7DGH4 F7DGH4 TRIM36 PTHR24099:SF18 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM36 aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule-based process#GO:0007017;sexual reproduction#GO:0019953;fertilization#GO:0009566;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;single fertilization#GO:0007338;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;acrosome reaction#GO:0007340 secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000019746.3|UniProtKB=F6WNR0 F6WNR0 NR5A1 PTHR24086:SF24 NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A STEROIDOGENIC FACTOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of RNA metabolic process#GO:0051252;hormone-mediated signaling pathway#GO:0009755;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;tissue development#GO:0009888;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of metabolic process#GO:0019222;response to hormone#GO:0009725;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 Gonadotropin-releasing hormone receptor pathway#P06664>SF1#P06848 MONDO|Ensembl=ENSMODG00000009845.4|UniProtKB=F6WAK9 F6WAK9 PTHR13179:SF8 DEP DOMAIN CONTAINING PROTEIN 5 GATOR1 COMPLEX PROTEIN DEPDC5 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;positive regulation of catabolic process#GO:0009896;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;negative regulation of TORC1 signaling#GO:1904262 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;Seh1-associated complex#GO:0035859;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000002532.4|UniProtKB=A0A5F8GMI8 A0A5F8GMI8 PTGER1 PTHR11866:SF3 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP1 SUBTYPE transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of biological quality#GO:0065008;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 PI3 kinase pathway#P00048>GPCR#P01204;Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 MONDO|Ensembl=ENSMODG00000045604.1|UniProtKB=A0A5F8H465 A0A5F8H465 REP15 PTHR36682:SF1 RAB15 EFFECTOR PROTEIN RAB15 EFFECTOR PROTEIN iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;transport#GO:0006810;metabolic process#GO:0008152;intracellular protein localization#GO:0008104;monoatomic ion transport#GO:0006811;protein transport#GO:0015031;monoatomic cation transport#GO:0006812;macromolecule metabolic process#GO:0043170;localization#GO:0051179;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;metal ion transport#GO:0030001 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;recycling endosome#GO:0055037;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 MONDO|Ensembl=ENSMODG00000011324.3|UniProtKB=F6WIJ1 F6WIJ1 ELOVL1 PTHR11157:SF19 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 1 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000024865.3|UniProtKB=F6ZIE0 F6ZIE0 ATG10 PTHR14957:SF1 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10 catalytic activity#GO:0003824;transferase activity#GO:0016740;Atg12 conjugating enzyme activity#GO:0061651;catalytic activity, acting on a protein#GO:0140096;Atg12 transferase activity#GO:0019777;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650 macroautophagy#GO:0016236;post-translational protein modification#GO:0043687;cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;mitophagy#GO:0000423;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;cellular component organization#GO:0016043;protein modification process#GO:0036211;primary metabolic process#GO:0044238;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;organelle assembly#GO:0070925 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000007366.4|UniProtKB=F7ADC1 F7ADC1 NIBAN1 PTHR14392:SF3 NIBAN FAMILY MEMBER PROTEIN NIBAN 1 MONDO|Ensembl=ENSMODG00000050290.1|UniProtKB=A0A5F8HFS8 A0A5F8HFS8 PTHR22803:SF116 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED REGENERATING ISLET-DERIVED PROTEIN 3-GAMMA molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 response to oxygen-containing compound#GO:1901700;immune system process#GO:0002376;response to nitrogen compound#GO:1901698;regulation of cell population proliferation#GO:0042127;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;response to external stimulus#GO:0009605;defense response#GO:0006952;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to hormone#GO:0009725;biological regulation#GO:0065007;response to other organism#GO:0051707;response to peptide hormone#GO:0043434;response to chemical#GO:0042221;defense response to other organism#GO:0098542 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000016177.4|UniProtKB=F7G8P3 F7G8P3 WFDC2 PTHR19441:SF34 WAP four-disulfide core domain protein WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 2 molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;defense response#GO:0006952;response to external stimulus#GO:0009605;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000019258.3|UniProtKB=F6QSH6 F6QSH6 PTHR13025:SF5 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN-CONTAINING PROTEIN D1 metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000011341.4|UniProtKB=F6W363 F6W363 NT5DC2 PTHR12103:SF14 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 2 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phosphatase#PC00181;nucleotide phosphatase#PC00173;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000040148.1|UniProtKB=A0A5F8GDR4 A0A5F8GDR4 C1orf115 PTHR14680:SF1 SI:DKEY-126G1.9-RELATED REQUIRED FOR DRUG-INDUCED DEATH PROTEIN 1 MONDO|Ensembl=ENSMODG00000010776.4|UniProtKB=F7FZQ6 F7FZQ6 PAFAH1B1 PTHR44129:SF16 WD REPEAT-CONTAINING PROTEIN POP1 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT BETA microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cell motility#GO:0048870;microtubule-based movement#GO:0007018;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;axonal transport#GO:0098930;retrograde axonal transport#GO:0008090;microtubule-based transport#GO:0099111;generation of neurons#GO:0048699;cellular localization#GO:0051641;anatomical structure development#GO:0048856;localization#GO:0051179;system development#GO:0048731;axo-dendritic transport#GO:0008088;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell migration#GO:0016477;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;intracellular transport#GO:0046907;transport#GO:0006810;developmental process#GO:0032502;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;neuron migration#GO:0001764;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;microtubule-based process#GO:0007017 microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;centrosome#GO:0005813;microtubule organizing center#GO:0005815;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;membraneless organelle#GO:0043228;chromosome#GO:0005694;kinetochore#GO:0000776;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687 MONDO|Ensembl=ENSMODG00000013594.3|UniProtKB=Q2ABA7 Q2ABA7 T2R3A PTHR11394:SF49 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 3 transmembrane signaling receptor activity#GO:0004888;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001989.3|UniProtKB=A0A5F8HFN7 A0A5F8HFN7 CYB561D1 PTHR15422:SF9 OS05G0565100 PROTEIN TRANSMEMBRANE REDUCTASE CYB561D1-RELATED MONDO|Ensembl=ENSMODG00000035743.2|UniProtKB=A0A5F8HED1 A0A5F8HED1 LOC103096080 PTHR31882:SF9 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER TNFAIP3 INTERACTING PROTEIN 1 cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to bacterium#GO:0009617;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;cellular response to molecule of bacterial origin#GO:0071219;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;response to lipopolysaccharide#GO:0032496 MONDO|Ensembl=ENSMODG00000017638.4|UniProtKB=F6Z4J7 F6Z4J7 PPT1 PTHR11247:SF81 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 PALMITOYL-PROTEIN THIOESTERASE 1 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;palmitoyl hydrolase activity#GO:0098599;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788 nervous system development#GO:0007399;endocytosis#GO:0006897;multicellular organismal process#GO:0032501;system development#GO:0048731;import into cell#GO:0098657;anatomical structure development#GO:0048856;establishment of localization#GO:0051234;localization#GO:0051179;multicellular organism development#GO:0007275;transport#GO:0006810;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000037260.1|UniProtKB=A0A5F8GJG8 A0A5F8GJG8 RRAS PTHR24070:SF245 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN R-RAS ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;establishment or maintenance of cell polarity#GO:0007163;Ras protein signal transduction#GO:0007265;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 Integrin signalling pathway#P00034>Ras#P00916;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;EGF receptor signaling pathway#P00018>Ras#P00552;TGF-beta signaling pathway#P00052>Ras-GDP#P01291 MONDO|Ensembl=ENSMODG00000013831.4|UniProtKB=A0A5F8H314 A0A5F8H314 SCUBE3 PTHR24046:SF2 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 3 animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;muscle cell development#GO:0055001;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;muscle cell differentiation#GO:0042692;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cell development#GO:0048468;signaling#GO:0023052;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 extracellular matrix glycoprotein#PC00100 MONDO|Ensembl=ENSMODG00000029528.2|UniProtKB=K7DZ42 K7DZ42 PTHR21687:SF5 PLASMALEMMA VESICLE-ASSOCIATED PROTEIN PLASMALEMMA VESICLE-ASSOCIATED PROTEIN blood circulation#GO:0008015;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of immune system process#GO:0002684;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cell migration#GO:0030335;positive regulation of locomotion#GO:0040017;system process#GO:0003008;regulation of cell migration#GO:0030334;regulation of leukocyte migration#GO:0002685;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;regulation of cell motility#GO:2000145;regulation of biological quality#GO:0065008;circulatory system process#GO:0003013 MONDO|Ensembl=ENSMODG00000047279.1|UniProtKB=A0A5F8GH08 A0A5F8GH08 LOC100028667 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018700.5|UniProtKB=F7AVD5 F7AVD5 NOTCH2 PTHR22804:SF62 AGGRECAN/VERSICAN PROTEOGLYCAN NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 2 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 Angiogenesis#P00005>Notch#P00255;Notch signaling pathway#P00045>Notch#P01099;Notch signaling pathway#P00045>NIct#P01119;Notch signaling pathway#P00045>NIcs#P01120;Alzheimer disease-presenilin pathway#P00004>Notch N-terminal fragment#P00171;Alzheimer disease-presenilin pathway#P00004>Notch fragment#P00154;Notch signaling pathway#P00045>Ntm#P01114;Alzheimer disease-presenilin pathway#P00004>Notch#P00176;Notch signaling pathway#P00045>Next#P01103;Alzheimer disease-presenilin pathway#P00004>Notch extracellular fragment#P00179;Alzheimer disease-presenilin pathway#P00004>Notch transmembrane fragment#P00135;Alzheimer disease-presenilin pathway#P00004>Notch C-terminal fragment#P00120;Alzheimer disease-presenilin pathway#P00004>NICD#P00122 MONDO|Ensembl=ENSMODG00000011943.4|UniProtKB=F7DDZ3 F7DDZ3 PTHR10996:SF257 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000027410.2|UniProtKB=K7E260 K7E260 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000002281.3|UniProtKB=F7CVN3 F7CVN3 PTHR22776:SF98 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MARVEL DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005495.3|UniProtKB=F7BXN1 F7BXN1 MGME1 PTHR31340:SF3 MITOCHONDRIAL GENOME MAINTENANCE EXONUCLEASE 1 MITOCHONDRIAL GENOME MAINTENANCE EXONUCLEASE 1 exonuclease activity#GO:0004527;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;5'-3' exonuclease activity#GO:0008409;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity#GO:0003824;DNA exonuclease activity#GO:0004529;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519 MONDO|Ensembl=ENSMODG00000002902.4|UniProtKB=F6PNJ3 F6PNJ3 MRPL12 PTHR45987:SF29 39S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;RNA binding#GO:0003723 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000003610.4|UniProtKB=F7C6F1 F7C6F1 MYO1F PTHR13140:SF663 MYOSIN UNCONVENTIONAL MYOSIN-IF isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146 establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;transport#GO:0006810;actin filament-based process#GO:0030029;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;actin-based cell projection#GO:0098858;microvillus#GO:0005902;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000016749.4|UniProtKB=A0A5F8GLW5 A0A5F8GLW5 LOC100023666 PTHR24342:SF19 SERINE/THREONINE-PROTEIN KINASE 17 OBSCURIN protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000012858.4|UniProtKB=A0A5F8GRK3 A0A5F8GRK3 ERBB2 PTHR24416:SF137 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of cellular process#GO:0048522;ERBB signaling pathway#GO:0038127;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;epidermal growth factor receptor signaling pathway#GO:0007173;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of epithelial cell proliferation#GO:0050679;regulation of cell communication#GO:0010646 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>EGFR#P00466;EGF receptor signaling pathway#P00018>EGFR#P00542 MONDO|Ensembl=ENSMODG00000048862.1|UniProtKB=A0A5F8GUC8 A0A5F8GUC8 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000000190.3|UniProtKB=F6TFR6 F6TFR6 CHAC1 PTHR12192:SF26 CATION TRANSPORT PROTEIN CHAC-RELATED GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 1 lyase activity#GO:0016829;catalytic activity#GO:0003824 catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000018119.4|UniProtKB=F7F1Y6 F7F1Y6 FAXC PTHR12289:SF76 METAXIN RELATED FAILED AXON CONNECTIONS HOMOLOG transporter#PC00227 MONDO|Ensembl=ENSMODG00000036973.1|UniProtKB=A0A5F8G4T5 A0A5F8G4T5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013400.5|UniProtKB=A0A5F8GRL3 A0A5F8GRL3 PNKP PTHR12083:SF9 BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE hydrolase activity#GO:0016787;phosphotransferase activity, alcohol group as acceptor#GO:0016773;nucleobase-containing compound kinase activity#GO:0019205;phosphoric ester hydrolase activity#GO:0042578;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;response to stimulus#GO:0050896;cellular response to stress#GO:0033554 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 nucleotide phosphatase#PC00173;phosphatase#PC00181;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000005189.4|UniProtKB=F7DNC3 F7DNC3 PLA2R1 PTHR22803:SF74 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED SECRETORY PHOSPHOLIPASE A2 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000016726.5|UniProtKB=A0A5F8HAZ9 A0A5F8HAZ9 TAF3 PTHR46452:SF1 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 3 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 3 protein binding#GO:0005515;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000044684.1|UniProtKB=F6Q1N0 F6Q1N0 LOC100023562 PTHR26450:SF194 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52N4 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001116.4|UniProtKB=F7DP72 F7DP72 ZMIZ1 PTHR10782:SF7 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN 1 ubiquitin-like protein ligase activity#GO:0061659;molecular function inhibitor activity#GO:0140678;acyltransferase activity#GO:0016746;SUMO ligase activity#GO:0061665;transcription regulator activity#GO:0140110;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;transcription coactivator activity#GO:0003713;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;regulation of RNA metabolic process#GO:0051252;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;metabolic process#GO:0008152;protein sumoylation#GO:0016925;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of transcription by RNA polymerase II#GO:0006357;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;chromosome#GO:0005694;organelle lumen#GO:0043233 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000025424.1|UniProtKB=F6W3D7 F6W3D7 PTHR11426:SF293 HISTONE H3 HISTONE H3.3C organelle assembly#GO:0070925;organelle localization#GO:0051640;nuclear division#GO:0000280;kinetochore assembly#GO:0051382;localization#GO:0051179;kinetochore organization#GO:0051383;organelle fission#GO:0048285;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic cell cycle#GO:0000278;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromosome localization#GO:0050000 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 MONDO|Ensembl=ENSMODG00000014440.4|UniProtKB=F7AUG9 F7AUG9 PTHR36462:SF1 CHROMOSOME 12 OPEN READING FRAME 71 CHROMOSOME 11 C12ORF71 HOMOLOG MONDO|Ensembl=ENSMODG00000014993.4|UniProtKB=F7CG33 F7CG33 ZDHHC21 PTHR22883:SF11 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC21 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 protein targeting#GO:0006605;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000006479.4|UniProtKB=F7F2Y7 F7F2Y7 C1orf174 PTHR28491:SF1 UPF0688 PROTEIN C1ORF174 UPF0688 PROTEIN C1ORF174 MONDO|Ensembl=ENSMODG00000004199.3|UniProtKB=F6Y900 F6Y900 DNAJC22 PTHR44733:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 22 DNAJ HOMOLOG SUBFAMILY C MEMBER 22 membrane#GO:0016020;cellular anatomical structure#GO:0110165 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000051526.1|UniProtKB=A0A5F8GED3 A0A5F8GED3 TMEM52B PTHR33955:SF1 TRANSMEMBRANE PROTEIN 52 TRANSMEMBRANE PROTEIN 52B MONDO|Ensembl=ENSMODG00000029353.2|UniProtKB=K7E120 K7E120 PTHR10500:SF7 BETA-MICROSEMINOPROTEIN MICROSEMINOPROTEIN BETA intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000019876.3|UniProtKB=F6WL30 F6WL30 PTHR31443:SF1 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 263 MONDO|Ensembl=ENSMODG00000013586.4|UniProtKB=F7AVV1 F7AVV1 PNPLA1 PTHR12406:SF23 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED OMEGA-HYDROXYCERAMIDE TRANSACYLASE hydrolase activity, acting on ester bonds#GO:0016788;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;triacylglycerol lipase activity#GO:0004806;acyltransferase activity#GO:0016746;hydrolase activity#GO:0016787 triglyceride catabolic process#GO:0019433;glycerolipid catabolic process#GO:0046503;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;homeostatic process#GO:0042592;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;acylglycerol metabolic process#GO:0006639;ceramide biosynthetic process#GO:0046513;neutral lipid catabolic process#GO:0046461;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid metabolic process#GO:0006638;acylglycerol catabolic process#GO:0046464;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000014358.2|UniProtKB=F6U4R6 F6U4R6 YPEL1 PTHR13848:SF1 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 1 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000003191.4|UniProtKB=F6VGS3 F6VGS3 VPS54 PTHR12965:SF0 VACUOLAR PROTEIN SORTING 54 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54 syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876 intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000010835.4|UniProtKB=F7BDF7 F7BDF7 PTHR10127:SF814 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING MEPRIN A SUBUNIT BETA catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000005467.2|UniProtKB=F7CGB0 F7CGB0 LOC100030289 PTHR26454:SF2 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6E1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000041596.1|UniProtKB=F7CX27 F7CX27 LOC100030333 PTHR26453:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G7 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011116.4|UniProtKB=F7BBG6 F7BBG6 PTHR15012:SF35 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM4 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840 apical junction complex#GO:0043296;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;cell junction#GO:0030054;membraneless organelle#GO:0043228;adherens junction#GO:0005912;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;plasma membrane region#GO:0098590;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000044528.1|UniProtKB=K7E2R6 K7E2R6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000046640.1|UniProtKB=A0A5F8H7D8 A0A5F8H7D8 LOC100010291 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000008456.4|UniProtKB=F7FRJ7 F7FRJ7 KIF27 PTHR24115:SF889 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF27 protein binding#GO:0005515;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000027909.2|UniProtKB=K7DZH0 K7DZH0 PTHR28584:SF1 FAMILY WITH SEQUENCE SIMILARITY 228 MEMBER A PROTEIN FAM228A MONDO|Ensembl=ENSMODG00000004824.5|UniProtKB=F6UM44 F6UM44 LMNB2 PTHR45721:SF2 LAMIN DM0-RELATED LAMIN-B2 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 establishment of organelle localization#GO:0051656;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;cellular localization#GO:0051641;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;heterochromatin formation#GO:0031507;nuclear migration#GO:0007097;localization#GO:0051179;organelle localization#GO:0051640;localization within membrane#GO:0051668;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;membrane organization#GO:0061024;macromolecule localization#GO:0033036;epigenetic regulation of gene expression#GO:0040029;protein localization to nucleus#GO:0034504;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleus organization#GO:0006997;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;regulation of gene expression#GO:0010468;nuclear envelope organization#GO:0006998;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;transport#GO:0006810 intracellular organelle lumen#GO:0070013;nuclear periphery#GO:0034399;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 FAS signaling pathway#P00020>Nuclear Lamin#P00616 MONDO|Ensembl=ENSMODG00000013727.4|UniProtKB=F6Z9W6 F6Z9W6 LLGL1 PTHR10241:SF21 LETHAL 2 GIANT LARVAE PROTEIN LETHAL(2) GIANT LARVAE PROTEIN HOMOLOG 1 binding#GO:0005488;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;syntaxin binding#GO:0019905;SNARE binding#GO:0000149;enzyme activator activity#GO:0008047;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 Golgi vesicle transport#GO:0048193;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;exocytosis#GO:0006887;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;regulation of establishment or maintenance of cell polarity#GO:0032878;vesicle-mediated transport#GO:0016192;regulation of signaling#GO:0023051;establishment or maintenance of cell polarity#GO:0007163;secretion by cell#GO:0032940;post-Golgi vesicle-mediated transport#GO:0006892;spindle localization#GO:0051653;cellular localization#GO:0051641;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;export from cell#GO:0140352;establishment of organelle localization#GO:0051656;regulation of response to stimulus#GO:0048583;transport#GO:0006810;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;establishment of spindle localization#GO:0051293;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of Notch signaling pathway#GO:0008593;actin filament-based process#GO:0030029;localization within membrane#GO:0051668;organelle localization#GO:0051640;cortical cytoskeleton organization#GO:0030865;secretion#GO:0046903;microtubule cytoskeleton organization#GO:0000226;cortical actin cytoskeleton organization#GO:0030866;localization#GO:0051179;establishment of cell polarity#GO:0030010;cell cycle#GO:0007049;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;Golgi to plasma membrane transport#GO:0006893 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;membrane#GO:0016020;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000025353.2|UniProtKB=F7E656 F7E656 C21orf140 PTHR35969:SF1 PROTEIN FAM243A-RELATED SIMILAR TO HUMAN CHROMOSOME 21 OPEN READING FRAME 140 MONDO|Ensembl=ENSMODG00000007090.3|UniProtKB=F6UEF7 F6UEF7 PTHR24031:SF221 RNA HELICASE EUKARYOTIC INITIATION FACTOR 4A-I protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;translational initiation#GO:0006413;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;cytoplasmic stress granule#GO:0010494;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000004313.3|UniProtKB=F6X726 F6X726 FAM53A PTHR28567:SF2 PROTEIN FAM53A-LIKE ISOFORM X1 PROTEIN FAM53A establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000017540.4|UniProtKB=A0A5F8HCZ7 A0A5F8HCZ7 UBAC1 PTHR46738:SF1 UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 MONDO|Ensembl=ENSMODG00000001274.4|UniProtKB=A0A5F8H950 A0A5F8H950 MEIS2 PTHR11850:SF47 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN MEIS2 sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 positive regulation of biological process#GO:0048518;sensory system development#GO:0048880;embryonic pattern specification#GO:0009880;head development#GO:0060322;nervous system development#GO:0007399;embryo development#GO:0009790;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;animal gross anatomical part developmental process#GO:0160108;eye development#GO:0001654;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;visual system development#GO:0150063;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000006389.4|UniProtKB=A0A5F8GVK3 A0A5F8GVK3 UEVLD PTHR23306:SF18 TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 3 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;ESCRT I complex#GO:0000813 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000051518.1|UniProtKB=A0A5F8H361 A0A5F8H361 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010367.3|UniProtKB=F6RN57 F6RN57 PTHR22705:SF0 ZINC FINGER, ZZ DOMAIN CONTAINING 3 ZZ-TYPE ZINC FINGER-CONTAINING PROTEIN 3 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000041779.1|UniProtKB=K7E0V1 K7E0V1 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000024805.1|UniProtKB=F7FAR7 F7FAR7 B3GALT1 PTHR11214:SF20 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 1 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 metabolic process#GO:0008152;oligosaccharide biosynthetic process#GO:0009312;oligosaccharide metabolic process#GO:0009311;primary metabolic process#GO:0044238;cellular process#GO:0009987;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;carbohydrate biosynthetic process#GO:0016051 membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000001351.3|UniProtKB=A0A5F8HK34 A0A5F8HK34 ATP5PB PTHR12733:SF3 MITOCHONDRIAL ATP SYNTHASE B CHAIN ATP SYNTHASE PERIPHERAL STALK SUBUNIT B, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;proton channel activity#GO:0015252;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;nucleoside phosphate biosynthetic process#GO:1901293;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407 cytoplasm#GO:0005737;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;proton-transporting ATP synthase complex#GO:0045259;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 primary active transporter#PC00068;ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000015663.3|UniProtKB=A0A5F8G6G1 A0A5F8G6G1 PTHR47634:SF6 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED SRSF PROTEIN KINASE 2 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;response to stimulus#GO:0050896;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions#GO:0000375;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000000934.4|UniProtKB=F7F7Y5 F7F7Y5 OSBPL9 PTHR10972:SF200 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 9 steroid binding#GO:0005496;lipid binding#GO:0008289;binding#GO:0005488;sterol binding#GO:0032934 cytosol#GO:0005829;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000005672.3|UniProtKB=F6VKP1 F6VKP1 CPLX1 PTHR16705:SF6 COMPLEXIN COMPLEXIN-1 binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic signaling#GO:0099536;neurotransmitter transport#GO:0006836;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;regulation of transport#GO:0051049;regulation of localization#GO:0032879;vesicle-mediated transport in synapse#GO:0099003;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;signaling#GO:0023052;export from cell#GO:0140352;regulation of cellular component organization#GO:0051128;regulation of signaling#GO:0023051;secretion by cell#GO:0032940;cellular localization#GO:0051641 axon#GO:0030424;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;synapse#GO:0045202;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;neuron projection terminus#GO:0044306;cell projection#GO:0042995;terminal bouton#GO:0043195;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cell junction#GO:0030054;axon terminus#GO:0043679;membrane#GO:0016020;neuron projection#GO:0043005;presynapse#GO:0098793;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000015127.4|UniProtKB=F7DJG4 F7DJG4 LOC100027167 PTHR24377:SF956 IP01015P-RELATED ZINC FINGER PROTEIN 892 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010356.4|UniProtKB=F6RP97 F6RP97 SHOC2 PTHR45752:SF26 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT PROTEIN SHOC-2 monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253 acidic amino acid transport#GO:0015800;cell surface receptor signaling pathway#GO:0007166;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;amino acid transport#GO:0006865;cellular response to nerve growth factor stimulus#GO:1990090;import into cell#GO:0098657;regulation of small GTPase mediated signal transduction#GO:0051056;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;monoatomic anion transmembrane transport#GO:0098656;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;import across plasma membrane#GO:0098739;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of response to stimulus#GO:0048583;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810;positive regulation of intracellular signal transduction#GO:1902533;establishment of localization#GO:0051234;nitrogen compound transport#GO:0071705;aspartate transmembrane transport#GO:0015810;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;monoatomic ion transmembrane transport#GO:0034220;dicarboxylic acid transport#GO:0006835;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;cell communication#GO:0007154;regulation of Ras protein signal transduction#GO:0046578;intracellular signal transduction#GO:0035556;positive regulation of signal transduction#GO:0009967;monoatomic anion transport#GO:0006820;cellular response to stimulus#GO:0051716;carbohydrate derivative transport#GO:1901264;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;carboxylic acid transmembrane transport#GO:1905039 intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000042523.1|UniProtKB=A0A5F8GWL1 A0A5F8GWL1 PTHR33426:SF30 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000001321.4|UniProtKB=F6RRP5 F6RRP5 PTHR11699:SF228 ALDEHYDE DEHYDROGENASE-RELATED 4-TRIMETHYLAMINOBUTYRALDEHYDE DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 biosynthetic process#GO:0009058;cellular process#GO:0009987;carnitine metabolic process#GO:0009437;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 MONDO|Ensembl=ENSMODG00000014076.2|UniProtKB=F6R525 F6R525 CFAP20 PTHR12458:SF11 ORF PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 20 cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;spermatogenesis#GO:0007283;developmental process#GO:0032502;male gamete generation#GO:0048232;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;sexual reproduction#GO:0019953;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;motile cilium assembly#GO:0044458;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;anatomical structure morphogenesis#GO:0009653 cytoplasmic microtubule#GO:0005881;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ciliary plasm#GO:0097014;sperm flagellum#GO:0036126;supramolecular polymer#GO:0099081;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 MONDO|Ensembl=ENSMODG00000013095.4|UniProtKB=F7EXM4 F7EXM4 EML1 PTHR13720:SF22 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 1 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;mitotic spindle#GO:0072686;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000016810.3|UniProtKB=F7FV94 F7FV94 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000003074.4|UniProtKB=F6PLG4 F6PLG4 PSMD6 PTHR14145:SF1 26S PROTESOME SUBUNIT 6 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 nucleus#GO:0005634;proteasome complex#GO:0000502;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000016308.3|UniProtKB=F7A674 F7A674 RNF114 PTHR46016:SF3 ZINC FINGER, RING/FYVE/PHD-TYPE E3 UBIQUITIN-PROTEIN LIGASE RNF114 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 MONDO|Ensembl=ENSMODG00000020329.4|UniProtKB=F7FWY4 F7FWY4 EGFLAM PTHR15036:SF88 PIKACHURIN-LIKE PROTEIN PIKACHURIN developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cell periphery#GO:0071944;basement membrane#GO:0005604;cell junction#GO:0030054;extracellular region#GO:0005576 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000046831.1|UniProtKB=A0A5F8HEL4 A0A5F8HEL4 SLC35F1 PTHR14233:SF10 DUF914-RELATED SOLUTE CARRIER FAMILY 35 MEMBER F1 MONDO|Ensembl=ENSMODG00000020835.4|UniProtKB=F6RL68 F6RL68 CADM4 PTHR45889:SF3 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 4 growth factor receptor binding#GO:0070851;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of wound healing#GO:0061041;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;cell adhesion#GO:0007155;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;regulation of response to wounding#GO:1903034;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-cell contact zone#GO:0044291;cell-cell junction#GO:0005911 MONDO|Ensembl=ENSMODG00000009406.4|UniProtKB=F6PUK6 F6PUK6 ABCA13 PTHR19229:SF113 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 13 ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876;establishment of localization#GO:0051234;localization#GO:0051179;lipid transport#GO:0006869 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000000968.2|UniProtKB=A0A5F8H8R4 A0A5F8H8R4 PIGF PTHR43157:SF79 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED GPI ETHANOLAMINE PHOSPHATE TRANSFERASE, STABILIZING SUBUNIT carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000025651.3|UniProtKB=F6XDZ9 F6XDZ9 PTHR10751:SF141 GUANYLATE BINDING PROTEIN GB1_RHD3-TYPE G DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 G-protein#PC00020;heterotrimeric G-protein#PC00117 MONDO|Ensembl=ENSMODG00000013356.3|UniProtKB=A0A5F8GUM8 A0A5F8GUM8 PTHR45913:SF11 EPM2A-INTERACTING PROTEIN 1 EPM2A-INTERACTING PROTEIN 1 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889;regulation of glycogen biosynthetic process#GO:0005979;regulation of carbohydrate metabolic process#GO:0006109;regulation of polysaccharide metabolic process#GO:0032881;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 MONDO|Ensembl=ENSMODG00000011776.4|UniProtKB=A0A5F8HKA3 A0A5F8HKA3 TRPM1 PTHR13800:SF13 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085 monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;transport#GO:0006810;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000014589.4|UniProtKB=F6V9Z6 F6V9Z6 WIZ PTHR24396:SF22 ZINC FINGER PROTEIN PROTEIN WIZ transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004594.4|UniProtKB=F6QIP9 F6QIP9 PIK3AP1 PTHR16267:SF12 BANK1/PIK3AP1 FAMILY MEMBER PHOSPHOINOSITIDE 3-KINASE ADAPTER PROTEIN 1 protein binding#GO:0005515;phosphatidylinositol 3-kinase binding#GO:0043548;signaling receptor binding#GO:0005102;binding#GO:0005488 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000045967.1|UniProtKB=A0A5F8GQW7 A0A5F8GQW7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000009781.4|UniProtKB=F6SZT8 F6SZT8 HIPK3 PTHR24058:SF53 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 3 protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transcription regulator activity#GO:0140110;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;transcription coactivator activity#GO:0003713;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transcription coregulator activity#GO:0003712;protein tyrosine kinase activity#GO:0004713;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;transferase activity#GO:0016740 response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;intrinsic apoptotic signaling pathway#GO:0097193;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;positive regulation of macromolecule metabolic process#GO:0010604;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;smoothened signaling pathway#GO:0007224;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;apoptotic signaling pathway#GO:0097190;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;DNA damage response#GO:0006974 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000011489.4|UniProtKB=F6V1R8 F6V1R8 PTHR24300:SF400 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C9 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;binding#GO:0005488;tetrapyrrole binding#GO:0046906 oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;olefinic compound metabolic process#GO:0120254;xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000005854.4|UniProtKB=F6T4X4 F6T4X4 PTHR24376:SF266 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 582 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000000333.3|UniProtKB=A0A5F8GSG0 A0A5F8GSG0 PTHR11711:SF422 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 3 guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf1#P00923 MONDO|Ensembl=ENSMODG00000006377.4|UniProtKB=F7G2I7 F7G2I7 CAND2 PTHR12696:SF2 TIP120 CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 2 metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular component assembly#GO:0022607;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein-containing complex assembly#GO:0065003;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein modification process#GO:0036211 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000013871.3|UniProtKB=F6W9C4 F6W9C4 TMIE PTHR28635:SF1 TRANSMEMBRANE INNER EAR EXPRESSED PROTEIN TRANSMEMBRANE INNER EAR EXPRESSED PROTEIN animal gross anatomical part developmental process#GO:0160108;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;nervous system process#GO:0050877;embryonic organ development#GO:0048568;anatomical structure development#GO:0048856;ear development#GO:0043583;anatomical structure morphogenesis#GO:0009653;sensory perception of sound#GO:0007605;animal organ morphogenesis#GO:0009887;sensory organ morphogenesis#GO:0090596;sensory organ development#GO:0007423;developmental process#GO:0032502;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;system process#GO:0003008;inner ear morphogenesis#GO:0042472;inner ear development#GO:0048839;multicellular organismal process#GO:0032501;embryo development#GO:0009790 MONDO|Ensembl=ENSMODG00000000661.3|UniProtKB=F6SBJ3 F6SBJ3 EXOC3 PTHR21292:SF13 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3 SNARE binding#GO:0000149;binding#GO:0005488;protein binding#GO:0005515 establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;exocytosis#GO:0006887;transport#GO:0006810;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987 cell periphery#GO:0071944;cell cortex#GO:0005938;cytoplasm#GO:0005737;exocyst#GO:0000145;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000004496.4|UniProtKB=F6VQI6 F6VQI6 EFS PTHR10654:SF14 CAS SCAFFOLDING PROTEIN EMBRYONAL FYN-ASSOCIATED SUBSTRATE signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell migration#GO:0016477;cell motility#GO:0048870;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cell-substrate junction#GO:0030055;plasma membrane#GO:0005886;focal adhesion#GO:0005925;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000048460.1|UniProtKB=A0A5F8HDQ9 A0A5F8HDQ9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010636.4|UniProtKB=F7D4X9 F7D4X9 SIRT5 PTHR11085:SF24 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;acyltransferase activity#GO:0016746;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;hydrolase activity#GO:0016787;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on a protein#GO:0140096;NAD-dependent protein lysine deacetylase activity#GO:0034979 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytosol#GO:0005829;nucleus#GO:0005634;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000010216.2|UniProtKB=F6RS10 F6RS10 IKBKB PTHR22969:SF7 IKB KINASE INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT BETA protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of DNA-templated transcription#GO:0045893;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;response to tumor necrosis factor#GO:0034612;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;tumor necrosis factor-mediated signaling pathway#GO:0033209;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cytokine-mediated signaling pathway#GO:0019221;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>IKK#P00313;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IKK#P00871;Interleukin signaling pathway#P00036>Ikk#P00968;Toll receptor signaling pathway#P00054>IKKbeta#P01360;B cell activation#P00010>IKK#P00397;T cell activation#P00053>IKK#P01330;PDGF signaling pathway#P00047>Ikk#P01146 MONDO|Ensembl=ENSMODG00000010648.4|UniProtKB=F7D4H4 F7D4H4 INTS6 PTHR12957:SF23 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED INTEGRATOR COMPLEX SUBUNIT 6 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;integrator complex#GO:0032039;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000005229.4|UniProtKB=F6ZCN0 F6ZCN0 B4GALT3 PTHR19300:SF33 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000004523.4|UniProtKB=F6UQB2 F6UQB2 F12 PTHR24253:SF26 TRANSMEMBRANE PROTEASE SERINE COAGULATION FACTOR XII serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000047598.1|UniProtKB=K7E059 K7E059 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000029617.2|UniProtKB=K7DZQ7 K7DZQ7 TAFA4 PTHR31770:SF7 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER TAFA CHEMOKINE LIKE FAMILY MEMBER 4 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chemokine#PC00074;cytokine#PC00083 MONDO|Ensembl=ENSMODG00000012593.4|UniProtKB=F6PIJ2 F6PIJ2 SFRP4 PTHR11309:SF7 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 4 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089 cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;non-canonical Wnt signaling pathway#GO:0035567;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>FrzB#P01461 MONDO|Ensembl=ENSMODG00000015393.4|UniProtKB=F6TKK2 F6TKK2 PTHR12635:SF7 RHO-GTPASE-ACTIVATING PROTEIN 6 FAMILY MEMBER RHO GTPASE ACTIVATING PROTEIN 36-RELATED molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 MONDO|Ensembl=ENSMODG00000040149.1|UniProtKB=A0A5F8GV67 A0A5F8GV67 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 cellular process#GO:0009987;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of immune response#GO:0050776;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000009529.3|UniProtKB=F7C4E3 F7C4E3 ARL14EP PTHR46536:SF1 ARL14 EFFECTOR PROTEIN ARL14 EFFECTOR PROTEIN MONDO|Ensembl=ENSMODG00000000730.4|UniProtKB=A0A5F8G8K9 A0A5F8G8K9 CC2D1B PTHR13076:SF5 COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1B cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000041379.1|UniProtKB=A0A5F8G336 A0A5F8G336 LOC100020204 PTHR24376:SF265 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 865 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000044935.1|UniProtKB=A0A5F8GSV9 A0A5F8GSV9 LOC100027468 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000036822.1|UniProtKB=A0A5F8G908 A0A5F8G908 PTHR16155:SF18 DED DOMAIN-CONTAINING PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 9-LIKE cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000002798.4|UniProtKB=A0A5F8GQ86 A0A5F8GQ86 AOPEP PTHR46627:SF1 AMINOPEPTIDASE O AMINOPEPTIDASE O membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 protease#PC00190 MONDO|Ensembl=ENSMODG00000006956.4|UniProtKB=F7CRQ5 F7CRQ5 CDH5 PTHR24027:SF89 CADHERIN-23 CADHERIN-5 enzyme binding#GO:0019899;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;phosphatase binding#GO:0019902;beta-catenin binding#GO:0008013;protein phosphatase binding#GO:0019903;protein binding#GO:0005515 anatomical structure development#GO:0048856;cell adhesion#GO:0007155;cell junction organization#GO:0034330;cell motility#GO:0048870;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell migration#GO:0016477;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;bicellular tight junction#GO:0005923;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;apical junction complex#GO:0043296;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;tight junction#GO:0070160;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000050585.1|UniProtKB=A0A5F8HC63 A0A5F8HC63 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000017449.4|UniProtKB=F6YLT2 F6YLT2 SHROOM2 PTHR15012:SF8 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;apical junction complex#GO:0043296;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;cell junction#GO:0030054;membraneless organelle#GO:0043228;adherens junction#GO:0005912 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000037718.1|UniProtKB=F6V6X4 F6V6X4 LOC100018829 PTHR48002:SF118 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025747.3|UniProtKB=F6T1S9 F6T1S9 PTHR11903:SF6 PROSTAGLANDIN G/H SYNTHASE PROSTAGLANDIN G_H SYNTHASE 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;unsaturated fatty acid biosynthetic process#GO:0006636;icosanoid biosynthetic process#GO:0046456;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;prostaglandin metabolic process#GO:0006693;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;arachidonate metabolic process#GO:0019369;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 neuron projection#GO:0043005;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cyclooxygenase#P00845 MONDO|Ensembl=ENSMODG00000005550.4|UniProtKB=A0A5F8GRP6 A0A5F8GRP6 FMR1 PTHR10603:SF4 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN FRAGILE X MESSENGER RIBONUCLEOPROTEIN 1 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 RNA localization#GO:0006403;RNA transport#GO:0050658;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleobase-containing compound transport#GO:0015931;positive regulation of neurogenesis#GO:0050769;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;establishment of RNA localization#GO:0051236;regulation of developmental process#GO:0050793;mRNA transport#GO:0051028;regulation of neurogenesis#GO:0050767;regulation of nervous system development#GO:0051960;nucleic acid transport#GO:0050657;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;localization#GO:0051179;regulation of RNA metabolic process#GO:0051252;positive regulation of translation#GO:0045727;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nitrogen compound transport#GO:0071705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;regulation of translation#GO:0006417;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;regulation of neuronal synaptic plasticity#GO:0048168;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;post-transcriptional regulation of gene expression#GO:0010608;regulation of synaptic plasticity#GO:0048167;regulation of cell differentiation#GO:0045595;transport#GO:0006810;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;positive regulation of nervous system development#GO:0051962;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;regulation of trans-synaptic signaling#GO:0099177;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;animal organ development#GO:0048513;regulation of mRNA metabolic process#GO:1903311;positive regulation of cell differentiation#GO:0045597 neuron projection#GO:0043005;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translation factor#PC00223;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000011696.4|UniProtKB=F7G3S4 F7G3S4 ACAD11 PTHR48083:SF42 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED ACYL-COA DEHYDROGENASE FAMILY MEMBER 11 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000019249.5|UniProtKB=F7C4K2 F7C4K2 SLC13A2 PTHR10283:SF139 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000010101.2|UniProtKB=F6X4N9 F6X4N9 GPR151 PTHR45695:SF1 LEUCOKININ RECEPTOR-RELATED G PROTEIN-COUPLED RECEPTOR 151 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037139.1|UniProtKB=A0A5F8GLL5 A0A5F8GLL5 MED11 PTHR22890:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000015676.4|UniProtKB=F7EHR6 F7EHR6 GTF3C2 PTHR15052:SF2 RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR COMPLEX SUBUNIT GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;rDNA binding#GO:0000182;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;rRNA transcription#GO:0009303;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular organelle#GO:0043229;transcription factor TFIIIC complex#GO:0000127;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000001920.4|UniProtKB=F7FIN7 F7FIN7 LOC100015874 PTHR14705:SF0 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT BETA CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT BETA sperm capacitation#GO:0048240;male gamete generation#GO:0048232;developmental maturation#GO:0021700;cellular process#GO:0009987;cellular developmental process#GO:0048869;cell maturation#GO:0048469;developmental process#GO:0032502;spermatogenesis#GO:0007283;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;gamete generation#GO:0007276;cell differentiation#GO:0030154;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;spermatid development#GO:0007286;sexual reproduction#GO:0019953;spermatid differentiation#GO:0048515 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;cilium#GO:0005929;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;cell periphery#GO:0071944;membrane#GO:0016020;transporter complex#GO:1990351;cation channel complex#GO:0034703 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000003881.4|UniProtKB=F7D789 F7D789 KANK3 PTHR24168:SF23 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 3 negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament length#GO:0030832;negative regulation of protein polymerization#GO:0032272;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex assembly#GO:0031333;regulation of biological quality#GO:0065008;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000049328.1|UniProtKB=A0A5F8GSD0 A0A5F8GSD0 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000010554.2|UniProtKB=A0A5F8GGJ8 A0A5F8GGJ8 TM2D2 PTHR21016:SF4 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 2 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;positive regulation of Notch signaling pathway#GO:0045747;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 MONDO|Ensembl=ENSMODG00000006159.4|UniProtKB=F7BS89 F7BS89 SYN2 PTHR10841:SF20 SYNAPSIN SYNAPSIN-2 cytoskeletal adaptor activity#GO:0008093;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 localization#GO:0051179;cellular localization#GO:0051641;synapse organization#GO:0050808;organelle localization#GO:0051640;cell junction organization#GO:0034330;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054;presynapse#GO:0098793;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synapsin#P05775 MONDO|Ensembl=ENSMODG00000045317.1|UniProtKB=A0A5F8H7E8 A0A5F8H7E8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000050332.1|UniProtKB=A0A5F8G4C7 A0A5F8G4C7 PTHR26453:SF601 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013907.2|UniProtKB=A0A5F8G7X3 A0A5F8G7X3 PTHR47979:SF12 DRAB11-RELATED RAS-RELATED PROTEIN RAB-2A GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000001070.3|UniProtKB=A0A5F8G6F3 A0A5F8G6F3 TMEM131 PTHR22050:SF1 RW1 PROTEIN HOMOLOG TRANSMEMBRANE PROTEIN 131 metabolic process#GO:0008152;cellular process#GO:0009987;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000004628.3|UniProtKB=F6UNQ1 F6UNQ1 HELT PTHR10985:SF8 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY AND ENHANCER OF SPLIT-RELATED PROTEIN HELT sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;anterior/posterior pattern specification#GO:0009952;regulation of multicellular organismal process#GO:0051239;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;Notch signaling pathway#GO:0007219;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;pattern specification process#GO:0007389;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 MONDO|Ensembl=ENSMODG00000016751.4|UniProtKB=H9H957 H9H957 VN2R657 PTHR24061:SF495 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2 RECEPTOR 657 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000011563.4|UniProtKB=F6QBL0 F6QBL0 PTHR15237:SF2 DNA REPAIR PROTEIN RAD9 CELL CYCLE CHECKPOINT CONTROL PROTEIN RAD9B DNA integrity checkpoint signaling#GO:0031570;mitotic DNA integrity checkpoint signaling#GO:0044774;response to radiation#GO:0009314;regulation of mitotic cell cycle#GO:0007346;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;mitotic cell cycle#GO:0000278;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular response to abiotic stimulus#GO:0071214;negative regulation of cell cycle#GO:0045786;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle phase transition#GO:1901988;response to abiotic stimulus#GO:0009628;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;response to ionizing radiation#GO:0010212;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;response to stimulus#GO:0050896;cellular response to radiation#GO:0071478;signaling#GO:0023052;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;negative regulation of mitotic cell cycle#GO:0045930 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;condensed chromosome#GO:0000793;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991 exodeoxyribonuclease#PC00098 MONDO|Ensembl=ENSMODG00000046768.1|UniProtKB=H9H6K1 H9H6K1 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000000896.4|UniProtKB=F7A7G7 F7A7G7 VDAC2 PTHR11743:SF12 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL NON-SELECTIVE VOLTAGE-GATED ION CHANNEL VDAC2 passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mitochondrial transport#GO:0006839;intracellular transport#GO:0046907;mitochondrial transmembrane transport#GO:1990542;transport#GO:0006810;transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000011569.3|UniProtKB=A0A5F8GCV2 A0A5F8GCV2 PRNP PTHR15506:SF2 DOPPEL PRION MAJOR PRION PROTEIN copper ion binding#GO:0005507;molecular adaptor activity#GO:0060090;cation binding#GO:0043169;metal ion binding#GO:0046872;molecular condensate scaffold activity#GO:0140693;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674 positive regulation of intracellular signal transduction#GO:1902533;response to metal ion#GO:0010038;regulation of response to stimulus#GO:0048583;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;positive regulation of calcium-mediated signaling#GO:0050850;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 cell periphery#GO:0071944;membrane microdomain#GO:0098857;membrane#GO:0016020;membrane raft#GO:0045121;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000013362.4|UniProtKB=F7DTU1 F7DTU1 DALRD3 PTHR16043:SF1 DALRD3 PROTEIN DALR ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 3 RNA binding#GO:0003723;tRNA binding#GO:0000049;binding#GO:0005488;nucleic acid binding#GO:0003676 gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414 MONDO|Ensembl=ENSMODG00000027534.2|UniProtKB=K7E442 K7E442 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000023394.2|UniProtKB=F6WQ56 F6WQ56 VN2R552 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009287.3|UniProtKB=A0A5F8GW05 A0A5F8GW05 ST3GAL5 PTHR13713:SF60 SIALYLTRANSFERASE LACTOSYLCERAMIDE ALPHA-2,3-SIALYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000008488.4|UniProtKB=F7G444 F7G444 CHD7 PTHR45623:SF20 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD7 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;histone binding#GO:0042393;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;ribonucleoside triphosphate phosphatase activity#GO:0017111;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;ATP hydrolysis activity#GO:0016887;DNA binding#GO:0003677;hydrolase activity#GO:0016787 animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;embryonic morphogenesis#GO:0048598;cellular process#GO:0009987;inner ear morphogenesis#GO:0042472;embryo development#GO:0009790;nervous system development#GO:0007399;heart development#GO:0007507;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;ear development#GO:0043583;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;sensory organ morphogenesis#GO:0090596;central nervous system development#GO:0007417;circulatory system development#GO:0072359;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222;inner ear development#GO:0048839;regulation of macromolecule biosynthetic process#GO:0010556;chromatin organization#GO:0006325;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;system development#GO:0048731;anatomical structure development#GO:0048856;heart morphogenesis#GO:0003007;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000009473.3|UniProtKB=F7FNS4 F7FNS4 CHMP3 PTHR10476:SF1 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 3 establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;late endosome to vacuole transport#GO:0045324 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000008033.4|UniProtKB=F6ZYR7 F6ZYR7 PTHR11915:SF232 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 4 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;central nervous system development#GO:0007417;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;system development#GO:0048731;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;central nervous system neuron differentiation#GO:0021953;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon development#GO:0061564 cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000041709.1|UniProtKB=A0A5F8HCI4 A0A5F8HCI4 LOC100023355 PTHR26451:SF52 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 12D2 binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000011975.4|UniProtKB=F7B9Y3 F7B9Y3 MRPL43 PTHR21396:SF2 39S RIBOSOMAL PROTEIN L43 LARGE RIBOSOMAL SUBUNIT PROTEIN ML43 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000044618.1|UniProtKB=A0A5F8GHE4 A0A5F8GHE4 LOC100023047 PTHR26452:SF930 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000006130.4|UniProtKB=F7E1Q6 F7E1Q6 GLE1 PTHR12960:SF0 GLE-1-RELATED MRNA EXPORT FACTOR GLE1 protein binding#GO:0005515;lipid binding#GO:0008289;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;translation initiation factor binding#GO:0031369;alcohol binding#GO:0043178;phospholipid binding#GO:0005543 establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;biosynthetic process#GO:0009058;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907 nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513 translation factor#PC00223 MONDO|Ensembl=ENSMODG00000051297.1|UniProtKB=A0A5F8GAT3 A0A5F8GAT3 LOC100619999 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011594.4|UniProtKB=F6UZN6 F6UZN6 CDKN3 PTHR23339:SF103 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE CYCLIN-DEPENDENT KINASE INHIBITOR 3 phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000003383.4|UniProtKB=A0A5F8H561 A0A5F8H561 RASAL1 PTHR10194:SF3 RAS GTPASE-ACTIVATING PROTEINS RASGAP-ACTIVATING-LIKE PROTEIN 1 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646;EGF receptor signaling pathway#P00018>GAP#P00546 MONDO|Ensembl=ENSMODG00000001485.4|UniProtKB=F7F4T7 F7F4T7 CHI3L2 PTHR11177:SF82 CHITINASE CHITINASE-3-LIKE PROTEIN 2 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 macromolecule metabolic process#GO:0043170;amino sugar catabolic process#GO:0046348;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000042718.1|UniProtKB=A0A5F8G5A2 A0A5F8G5A2 CABYR PTHR15494:SF0 CALCIUM-BINDING TYROSINE PHOSPHORYLATION-REGULATED PROTEIN CALCIUM-BINDING TYROSINE PHOSPHORYLATION-REGULATED PROTEIN metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000000279.3|UniProtKB=A0A5F8GGW1 A0A5F8GGW1 UBE2S PTHR24068:SF126 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 S ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;catabolic process#GO:0009056 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000027363.2|UniProtKB=K7E1Y0 K7E1Y0 TNFRSF9 PTHR47139:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;biological regulation#GO:0065007;regulation of biological process#GO:0050789 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017370.3|UniProtKB=A0A5F8HJ87 A0A5F8HJ87 AMELX PTHR46794:SF2 AMELOGENIN, Y ISOFORM AMELOGENIN, X ISOFORM extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 anatomical structure formation involved in morphogenesis#GO:0048646;anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502;biomineral tissue development#GO:0031214;animal gross anatomical part developmental process#GO:0160108;enamel mineralization#GO:0070166;odontogenesis#GO:0042476;odontogenesis of dentin-containing tooth#GO:0042475;tissue development#GO:0009888;animal organ morphogenesis#GO:0009887;anatomical structure morphogenesis#GO:0009653;amelogenesis#GO:0097186 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 MONDO|Ensembl=ENSMODG00000025165.2|UniProtKB=A8E6E4 A8E6E4 LOC100021258 PTHR11691:SF73 TYPE I INTERFERON INTERFERON BETA protein binding#GO:0005515;protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 response to chemical#GO:0042221;lymphocyte activation#GO:0046649;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;T cell activation involved in immune response#GO:0002286;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;lymphocyte activation involved in immune response#GO:0002285;cellular process#GO:0009987;B cell activation#GO:0042113;humoral immune response#GO:0006959;immune effector process#GO:0002252;natural killer cell activation#GO:0030101;cell surface receptor signaling pathway#GO:0007166;leukocyte activation involved in immune response#GO:0002366;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;T cell activation#GO:0042110;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to peptide#GO:1901652;cell activation involved in immune response#GO:0002263;immune system process#GO:0002376;B cell activation involved in immune response#GO:0002312;type I interferon-mediated signaling pathway#GO:0060337;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;adaptive immune response#GO:0002250;response to other organism#GO:0051707;immune response#GO:0006955;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cytokine-mediated signaling pathway#GO:0019221;cell activation#GO:0001775 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127;cytokine#PC00083 Toll receptor signaling pathway#P00054>Gene trancription#G01550 MONDO|Ensembl=ENSMODG00000004897.3|UniProtKB=F7C222 F7C222 AGTR2 PTHR24228:SF8 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR TYPE-2 ANGIOTENSIN II RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 defense response#GO:0006952;system process#GO:0003008;regulation of anatomical structure size#GO:0090066;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;biological regulation#GO:0065007;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;regulation of biological quality#GO:0065008;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;inflammatory response#GO:0006954;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;vasodilation#GO:0042311;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000025553.3|UniProtKB=F6UIL6 F6UIL6 C4HXorf58 PTHR33504:SF1 NADH DEHYDROGENASE (UBIQUINONE) 1 BETA SUBCOMPLEX, 4 SIMILAR TO HUMAN CHROMOSOME X OPEN READING FRAME 58 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000018602.3|UniProtKB=F7BQ22 F7BQ22 RBP2 PTHR11955:SF59 FATTY ACID BINDING PROTEIN RETINOL-BINDING PROTEIN 2 organic acid binding#GO:0043177;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;lipid binding#GO:0008289;fatty acid binding#GO:0005504 monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;localization#GO:0051179;fatty acid transport#GO:0015908;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;lipid localization#GO:0010876;lipid transport#GO:0006869;macromolecule localization#GO:0033036 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000020605.3|UniProtKB=F6ZBI7 F6ZBI7 HADH PTHR43561:SF3 FAMILY NOT NAMED HYDROXYACYL-COENZYME A DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;lipid modification#GO:0030258;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329 MONDO|Ensembl=ENSMODG00000023433.3|UniProtKB=F6WKP9 F6WKP9 LOC103106539 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000049145.1|UniProtKB=A0A5F8H7H5 A0A5F8H7H5 RNF223 PTHR22791:SF4 RING-TYPE DOMAIN-CONTAINING PROTEIN RING FINGER PROTEIN 223 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000015094.5|UniProtKB=F7F3E0 F7F3E0 ANO8 PTHR12308:SF51 ANOCTAMIN ANOCTAMIN-8 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 biological regulation#GO:0065007;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000024547.3|UniProtKB=F7FFE9 F7FFE9 LOC100018588 PTHR24256:SF173 TRYPTASE-RELATED SERINE PROTEASE 30 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000011083.3|UniProtKB=F7E5T5 F7E5T5 LOC100017911 PTHR26450:SF70 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR OLFR593 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012906.3|UniProtKB=F7GKQ3 F7GKQ3 GMPPB PTHR22572:SF15 SUGAR-1-PHOSPHATE GUANYL TRANSFERASE MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE CATALYTIC SUBUNIT BETA nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;macromolecule metabolic process#GO:0043170;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organophosphate metabolic process#GO:0019637;glycoprotein biosynthetic process#GO:0009101 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220 Mannose metabolism#P02752>Mannose 1-P guanylyl transferase#P03018 MONDO|Ensembl=ENSMODG00000049437.1|UniProtKB=A0A5F8H4D5 A0A5F8H4D5 PTHR19965:SF22 RNA AND EXPORT FACTOR BINDING PROTEIN CHROMATIN TARGET OF PRMT1-LIKE 1 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000011227.3|UniProtKB=F6S7J7 F6S7J7 NHLRC1 PTHR24104:SF64 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED E3 UBIQUITIN-PROTEIN LIGASE NHLRC1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000016430.3|UniProtKB=F6XQW0 F6XQW0 MC3R PTHR22750:SF4 G-PROTEIN COUPLED RECEPTOR MELANOCORTIN RECEPTOR 3 hormone binding#GO:0042562;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;peptide hormone binding#GO:0017046;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000042501.1|UniProtKB=A0A5F8GUY7 A0A5F8GUY7 C1H9orf43 PTHR36130:SF1 RIKEN CDNA 4933430I17 GENE RIKEN CDNA 4933430I17 GENE MONDO|Ensembl=ENSMODG00000028962.1|UniProtKB=K7E0B4 K7E0B4 PTHR24068:SF72 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2Q-LIKE PROTEIN 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000046111.1|UniProtKB=A0A5F8HH31 A0A5F8HH31 ILKAP PTHR13832:SF883 PROTEIN PHOSPHATASE 2C INTEGRIN-LINKED KINASE-ASSOCIATED SERINE_THREONINE PHOSPHATASE 2C hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000021072.5|UniProtKB=F6V1S7 F6V1S7 PAXBP1 PTHR12214:SF2 GC-RICH SEQUENCE DNA-BINDING FACTOR PAX3- AND PAX7-BINDING PROTEIN 1 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000020864.3|UniProtKB=F6XL36 F6XL36 PTHR44427:SF21 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CEA CELL ADHESION MOLECULE 19 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000049693.1|UniProtKB=A0A5F8GKD2 A0A5F8GKD2 PENK PTHR11438:SF3 PROENKEPHALIN PROENKEPHALIN-A molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;system process#GO:0003008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;sensory perception of pain#GO:0019233;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;neuronal cell body#GO:0043025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell body#GO:0044297;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle lumen#GO:0043233;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;endomembrane system#GO:0012505;secretory vesicle#GO:0099503;membrane-enclosed lumen#GO:0031974 intercellular signal molecule#PC00207;peptide hormone#PC00179;neuropeptide#PC00162 Opioid proenkephalin pathway#P05915>proenkephalin#P05995;Opioid proenkephalin pathway#P05915>Enkephalin#P05991;Enkephalin release#P05913>preproenkephalin mRNA#G06046;Enkephalin release#P05913>preproenkephalin#G06045;Opioid proenkephalin pathway#P05915>peptide F#P05987;Opioid proenkephalin pathway#P05915>leu-Enkephalin#P05989;Enkephalin release#P05913>Enkephalin#P05976;Opioid proenkephalin pathway#P05915>met-Enkephalin#P05992;Opioid proenkephalin pathway#P05915>peptide E#P05988 MONDO|Ensembl=ENSMODG00000012842.4|UniProtKB=F7CT40 F7CT40 PTHR15141:SF75 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 ELONGIN-A macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000018936.4|UniProtKB=F7GJP3 F7GJP3 ANXA5 PTHR10502:SF26 ANNEXIN ANNEXIN A5 lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;phospholipid binding#GO:0005543;ion binding#GO:0043167 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle#GO:0031982;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 calcium-binding protein#PC00060 Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#G06684;Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#G06897;Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#P06814 MONDO|Ensembl=ENSMODG00000049721.1|UniProtKB=A0A5F8H2I2 A0A5F8H2I2 LOC100027742 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019398.4|UniProtKB=H9H7C5 H9H7C5 TAC3 PTHR15536:SF1 TACHYKININ-3 TACHYKININ-3 multicellular organismal process#GO:0032501;positive regulation of blood pressure#GO:0045777;blood circulation#GO:0008015;biological regulation#GO:0065007;regulation of blood pressure#GO:0008217;regulation of biological quality#GO:0065008;system process#GO:0003008;circulatory system process#GO:0003013 MONDO|Ensembl=ENSMODG00000013202.4|UniProtKB=F7EWI7 F7EWI7 IRX5 PTHR11211:SF17 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-5 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000021192.4|UniProtKB=F6XVT6 F6XVT6 FARSB PTHR10947:SF0 PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 PHENYLALANINE--TRNA LIGASE BETA SUBUNIT catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;catalytic complex#GO:1902494 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000016966.4|UniProtKB=F6UMR7 F6UMR7 HELZ2 PTHR43788:SF16 DNA2/NAM7 HELICASE FAMILY MEMBER 3'-5' EXORIBONUCLEASE HELZ2 ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to stimulus#GO:0050896 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000025691.3|UniProtKB=F6TJN3 F6TJN3 CIMAP3 PTHR31508:SF2 PROTEIN PITCHFORK CILIARY MICROTUBULE-ASSOCIATED PROTEIN 3 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000043719.1|UniProtKB=A0A5F8GIY4 A0A5F8GIY4 PTHR40389:SF3 ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED IGE-BINDING PROTEIN MONDO|Ensembl=ENSMODG00000003070.4|UniProtKB=A0A5F8GNH0 A0A5F8GNH0 TOX2 PTHR45781:SF5 AGAP000281-PA TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 2 DNA binding#GO:0003677;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 MONDO|Ensembl=ENSMODG00000001966.4|UniProtKB=F6V274 F6V274 NMRK1 PTHR10285:SF126 URIDINE KINASE NICOTINAMIDE RIBOSIDE KINASE 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 kinase#PC00137;nucleotide kinase#PC00172 MONDO|Ensembl=ENSMODG00000001925.4|UniProtKB=F6W0T8 F6W0T8 LOC100619241 PTHR14705:SF0 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT BETA CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT BETA sperm capacitation#GO:0048240;developmental maturation#GO:0021700;male gamete generation#GO:0048232;cellular process#GO:0009987;cell maturation#GO:0048469;cellular developmental process#GO:0048869;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;reproductive process#GO:0022414;cell differentiation#GO:0030154;gamete generation#GO:0007276;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;spermatid development#GO:0007286;spermatid differentiation#GO:0048515 membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;calcium channel complex#GO:0034704;plasma membrane protein complex#GO:0098797;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transporter complex#GO:1990351 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000011485.4|UniProtKB=F6V2Q2 F6V2Q2 PHF7 PTHR12420:SF47 PHD FINGER PROTEIN E3 UBIQUITIN-PROTEIN LIGASE PHF7 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000004252.4|UniProtKB=F6TW41 F6TW41 PTHR11616:SF129 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER serotonin binding#GO:0051378;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;heterocyclic compound binding#GO:1901363;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;solute:sodium symporter activity#GO:0015370;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857 organic hydroxy compound transport#GO:0015850;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;import into cell#GO:0098657;amino acid transport#GO:0006865;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;neurotransmitter transport#GO:0006836;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;nitrogen compound transport#GO:0071705 cell junction#GO:0030054;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000009094.3|UniProtKB=F7FCB4 F7FCB4 LOC100010462 PTHR26453:SF18 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T2-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005632.4|UniProtKB=F7GGD2 F7GGD2 IFT43 PTHR33724:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 43 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 43 HOMOLOG cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996 intraciliary transport particle#GO:0030990;cilium#GO:0005929;intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 MONDO|Ensembl=ENSMODG00000020196.4|UniProtKB=F7FXQ0 F7FXQ0 ADGRV1 PTHR46682:SF1 ADHESION G-PROTEIN COUPLED RECEPTOR V1 ADHESION G PROTEIN-COUPLED RECEPTOR V1 cyclase regulator activity#GO:0010851;enzyme inhibitor activity#GO:0004857;G protein-coupled receptor activity#GO:0004930;molecular function regulator activity#GO:0098772;signaling receptor activity#GO:0038023;cyclase inhibitor activity#GO:0010852;binding#GO:0005488;adenylate cyclase regulator activity#GO:0010854;transmembrane signaling receptor activity#GO:0004888;adenylate cyclase inhibitor activity#GO:0010855;protein binding#GO:0005515;molecular transducer activity#GO:0060089;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 system process#GO:0003008;response to calcium ion#GO:0051592;sensory perception#GO:0007600;response to metal ion#GO:0010038;sensory perception of mechanical stimulus#GO:0050954;nervous system process#GO:0050877;cellular response to chemical stimulus#GO:0070887;visual perception#GO:0007601;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of sound#GO:0007605;multicellular organismal process#GO:0032501;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;sensory perception of light stimulus#GO:0050953 cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;stereocilium#GO:0032420;cytoskeleton#GO:0005856;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000003392.3|UniProtKB=F6Z111 F6Z111 PTHR18952:SF95 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 4 catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 intracellular organelle#GO:0043229;apical part of cell#GO:0045177;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000015471.5|UniProtKB=F6ZVL3 F6ZVL3 PTPRZ1 PTHR19134:SF461 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;oligodendrocyte differentiation#GO:0048709;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;gliogenesis#GO:0042063;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000013029.4|UniProtKB=H9H6L6 H9H6L6 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020565.3|UniProtKB=A0A5F8GRD1 A0A5F8GRD1 PTHR13204:SF1 PTD012 PROTEIN BETA-KETO L-GULONATE DECARBOXYLASE hydrolase activity, acting on ester bonds#GO:0016788;zinc ion binding#GO:0008270;catalytic activity#GO:0003824;cation binding#GO:0043169;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000015271.4|UniProtKB=F7CM76 F7CM76 CENPN PTHR46790:SF1 CENTROMERE PROTEIN N CENTROMERE PROTEIN N nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000016222.4|UniProtKB=F7FLY6 F7FLY6 SERPINI1 PTHR11461:SF50 SERINE PROTEASE INHIBITOR, SERPIN NEUROSERPIN endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000016043.3|UniProtKB=A0A5F8GEX1 A0A5F8GEX1 PTHR26453:SF617 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2H2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048105.1|UniProtKB=A0A5F8GA12 A0A5F8GA12 PTHR22776:SF98 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MARVEL DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000050926.1|UniProtKB=A0A5F8GZQ4 A0A5F8GZQ4 PTHR23267:SF486 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 14_DELTA VARIABLE 4 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000045894.1|UniProtKB=A0A5F8GEE2 A0A5F8GEE2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000018127.4|UniProtKB=F7F1R1 F7F1R1 MMS22L PTHR28547:SF1 PROTEIN MMS22-LIKE PROTEIN MMS22-LIKE response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;DNA-templated DNA replication#GO:0006261;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310 membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000016661.4|UniProtKB=H9H714 H9H714 PTHR44813:SF1 MITOGEN-ACTIVATED PROTEIN KINASE-BINDING PROTEIN 1 MITOGEN-ACTIVATED PROTEIN KINASE-BINDING PROTEIN 1 MONDO|Ensembl=ENSMODG00000012302.4|UniProtKB=A0A5F8GGX6 A0A5F8GGX6 DENR PTHR12789:SF0 DENSITY-REGULATED PROTEIN HOMOLOG DENSITY-REGULATED PROTEIN binding#GO:0005488;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021 biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000024214.2|UniProtKB=A0A5F8H1N1 A0A5F8H1N1 LOC130454611 PTHR10903:SF199 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000024137.3|UniProtKB=F6UKS9 F6UKS9 PTHR10877:SF145 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-1-LIKE PROTEIN 1 calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873 response to stimulus#GO:0050896;response to external stimulus#GO:0009605;detection of stimulus#GO:0051606;detection of mechanical stimulus#GO:0050982;response to abiotic stimulus#GO:0009628;response to mechanical stimulus#GO:0009612 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000046603.1|UniProtKB=A0A5F8GL38 A0A5F8GL38 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000037836.1|UniProtKB=A0A5F8G2G6 A0A5F8G2G6 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000005063.4|UniProtKB=F7A7Z0 F7A7Z0 IGSF3 PTHR12207:SF21 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 3 membrane#GO:0016020;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000004861.4|UniProtKB=F6TNZ8 F6TNZ8 TLR3 PTHR24365:SF524 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;regulation of innate immune response#GO:0045088;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;toll-like receptor signaling pathway#GO:0002224;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000029770.2|UniProtKB=K7E5U9 K7E5U9 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000049253.1|UniProtKB=A0A5F8HI93 A0A5F8HI93 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000005827.2|UniProtKB=F6U1V1 F6U1V1 MYL5 PTHR23049:SF8 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN LIGHT CHAIN 5 myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092;metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000008941.4|UniProtKB=F7GD46 F7GD46 RASL11A PTHR45704:SF3 RAS-LIKE FAMILY MEMBER 11 RAS-LIKE PROTEIN FAMILY MEMBER 11A MONDO|Ensembl=ENSMODG00000038833.1|UniProtKB=F6V0J2 F6V0J2 LOC100026580 PTHR48018:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000029382.2|UniProtKB=K7E3S4 K7E3S4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001744.3|UniProtKB=F6WZU5 F6WZU5 SLC6A17 PTHR11616:SF102 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER SLC6A17 metal ion transport#GO:0030001;L-leucine transport#GO:0015820;sodium ion transport#GO:0006814;monoatomic ion transport#GO:0006811;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;glycine transport#GO:0015816;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;branched-chain amino acid transport#GO:0015803;establishment of localization#GO:0051234;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;amino acid transport#GO:0006865;alanine transport#GO:0032328 cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 MONDO|Ensembl=ENSMODG00000009963.4|UniProtKB=F6R843 F6R843 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000017195.4|UniProtKB=F6XFR4 F6XFR4 SHE PTHR15127:SF29 HEAVYWEIGHT, ISOFORM A SH2 DOMAIN-CONTAINING ADAPTER PROTEIN E protein binding#GO:0005515;binding#GO:0005488 MONDO|Ensembl=ENSMODG00000007016.4|UniProtKB=F6XCC9 F6XCC9 ACSM3 PTHR43605:SF7 ACYL-COENZYME A SYNTHETASE ACYL-COENZYME A SYNTHETASE ACSM3, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 carboxylic acid biosynthetic process#GO:0046394;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;monocarboxylic acid biosynthetic process#GO:0072330 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;ligase#PC00142 MONDO|Ensembl=ENSMODG00000004011.4|UniProtKB=F7D7E1 F7D7E1 MAL2 PTHR22776:SF42 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN PROTEIN MAL2 regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;membrane microdomain#GO:0098857;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;membrane#GO:0016020;membrane raft#GO:0045121;vesicle#GO:0031982 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007076.4|UniProtKB=A0A5F8G5N0 A0A5F8G5N0 LYRM1 PTHR14273:SF0 LYR MOTIF-CONTAINING PROTEIN 1 LYR MOTIF-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000046582.1|UniProtKB=A0A5F8H4B7 A0A5F8H4B7 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000007352.3|UniProtKB=F7B0C1 F7B0C1 FKBP3 PTHR46493:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000017281.2|UniProtKB=F6SMX3 F6SMX3 GJE1 PTHR11984:SF1 CONNEXIN GAP JUNCTION EPSILON-1 PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;anchoring junction#GO:0070161;cell junction#GO:0030054 gap junction#PC00105;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000007437.4|UniProtKB=A0A5F8GJU6 A0A5F8GJU6 TENM2 PTHR11219:SF8 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-2 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 axonogenesis#GO:0007409;neuron development#GO:0048666;synaptic membrane adhesion#GO:0099560;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175;cellular process#GO:0009987;anatomical structure development#GO:0048856;system development#GO:0048731;synapse organization#GO:0050808;cell junction organization#GO:0034330;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411 cell junction#GO:0030054;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000044926.1|UniProtKB=A0A5F8GZN1 A0A5F8GZN1 JUNB PTHR11462:SF37 JUN TRANSCRIPTION FACTOR-RELATED TRANSCRIPTION FACTOR JUNB cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 response to steroid hormone#GO:0048545;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cell cycle#GO:0051726;positive regulation of transcription by RNA polymerase II#GO:0045944;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;response to lipid#GO:0033993;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>JUN#P06757;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AP-1#P00838 MONDO|Ensembl=ENSMODG00000010740.4|UniProtKB=A0A5F8HAC6 A0A5F8HAC6 LOC100019992 PTHR10340:SF25 SPHINGOMYELIN PHOSPHODIESTERASE ACID SPHINGOMYELINASE-LIKE PHOSPHODIESTERASE 3B phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000018477.4|UniProtKB=F7CAD9 F7CAD9 MEI4 PTHR28575:SF1 MEIOSIS-SPECIFIC PROTEIN MEI4 MEIOSIS-SPECIFIC PROTEIN MEI4 meiotic nuclear division#GO:0140013;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;developmental process#GO:0032502;spermatogenesis#GO:0007283;male gamete generation#GO:0048232;nucleobase-containing compound metabolic process#GO:0006139;organelle fission#GO:0048285;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;germ cell development#GO:0007281;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;metabolic process#GO:0008152;chromosome segregation#GO:0007059;homologous chromosome pairing at meiosis#GO:0007129;oogenesis#GO:0048477;meiotic DNA double-strand break formation#GO:0042138;organelle organization#GO:0006996;cellular process#GO:0009987;nuclear division#GO:0000280;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle process#GO:0022402 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;synaptonemal structure#GO:0099086;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228 MONDO|Ensembl=ENSMODG00000015909.3|UniProtKB=F6ZS16 F6ZS16 PTHR22760:SF3 GLYCOSYLTRANSFERASE GPI ALPHA-1,2-MANNOSYLTRANSFERASE 4 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030 protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000009414.4|UniProtKB=F7C5D6 F7C5D6 CHRNA1 PTHR18945:SF74 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA acetylcholine receptor activity#GO:0015464;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic cation transmembrane transporter activity#GO:0008324;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261 regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;neuromuscular synaptic transmission#GO:0007274;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cellular response to chemical stimulus#GO:0070887;nervous system process#GO:0050877;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;signaling#GO:0023052;skeletal muscle contraction#GO:0003009;muscle system process#GO:0003012;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;system process#GO:0003008;transport#GO:0006810;muscle contraction#GO:0006936;multicellular organismal process#GO:0032501;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;response to nitrogen compound#GO:1901698;trans-synaptic signaling#GO:0099537;neuromuscular process#GO:0050905;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;striated muscle contraction#GO:0006941;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;modulation of chemical synaptic transmission#GO:0050804;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716 plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088 MONDO|Ensembl=ENSMODG00000016018.4|UniProtKB=F7EG41 F7EG41 PNPLA8 PTHR24185:SF10 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA A2-type glycerophospholipase activity#GO:0004623;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;olefinic compound metabolic process#GO:0120254;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;icosanoid metabolic process#GO:0006690;monocarboxylic acid metabolic process#GO:0032787;long-chain fatty acid metabolic process#GO:0001676;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;arachidonate metabolic process#GO:0019369 membrane#GO:0016020;cellular anatomical structure#GO:0110165 phospholipase#PC00186;lipase#PC00143;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000045138.1|UniProtKB=A0A5F8H2V0 A0A5F8H2V0 PTHR22891:SF46 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PIWI-LIKE PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;nuclease activity#GO:0004518;RNA binding#GO:0003723;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519 RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;piRNA processing#GO:0034587;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;male gamete generation#GO:0048232;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulatory ncRNA-mediated gene silencing#GO:0031047;spermatogenesis#GO:0007283;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;membraneless organelle#GO:0043228 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000010441.5|UniProtKB=F6YSE3 F6YSE3 PCDH12 PTHR24028:SF42 CADHERIN-87A PROTOCADHERIN-12 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000016704.4|UniProtKB=F7D2F1 F7D2F1 WFIKKN1 PTHR45938:SF6 ACP24A4-RELATED WAP, KAZAL, IMMUNOGLOBULIN, KUNITZ AND NTR DOMAIN-CONTAINING PROTEIN 1 transforming growth factor beta binding#GO:0050431;signaling receptor regulator activity#GO:0030545;cytokine binding#GO:0019955;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor inhibitor activity#GO:0030547;molecular function inhibitor activity#GO:0140678;growth factor binding#GO:0019838;protein binding#GO:0005515 regulation of biological process#GO:0050789;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to transforming growth factor beta#GO:0071559;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000044591.1|UniProtKB=A0A5F8GQL4 A0A5F8GQL4 C8orf82 PTHR31449:SF3 UPF0598 PROTEIN C8ORF82 UPF0598 PROTEIN C8ORF82 MONDO|Ensembl=ENSMODG00000021274.4|UniProtKB=A0A5F8GK84 A0A5F8GK84 PTHR23093:SF11 SIMILAR TO CHROMOSOME 3 OPEN READING FRAME 20 GLUTAMATE-RICH PROTEIN 6 MONDO|Ensembl=ENSMODG00000039999.1|UniProtKB=A0A5F8GAV5 A0A5F8GAV5 GCSH PTHR11715:SF3 GLYCINE CLEAVAGE SYSTEM H PROTEIN GLYCINE CLEAVAGE SYSTEM H PROTEIN-RELATED oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000019629.4|UniProtKB=F7GLC9 F7GLC9 CDK5RAP2 PTHR46930:SF1 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 2 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;establishment of organelle localization#GO:0051656;centrosome cycle#GO:0007098;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular localization#GO:0051641;regulation of signaling#GO:0023051;regulation of chromosome separation#GO:1905818;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;centrosome duplication#GO:0051298;cellular component organization or biogenesis#GO:0071840;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;establishment of cell polarity#GO:0030010;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of organelle organization#GO:0010639;regulation of mitotic sister chromatid segregation#GO:0033047;microtubule bundle formation#GO:0001578;regulation of microtubule-based process#GO:0032886;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;establishment of spindle localization#GO:0051293;mitotic cell cycle process#GO:1903047;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of sister chromatid segregation#GO:0033045;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;regulation of mitotic cell cycle phase transition#GO:1901990;spindle localization#GO:0051653;establishment or maintenance of cell polarity#GO:0007163;regulation of intracellular signal transduction#GO:1902531;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;establishment of mitotic spindle localization#GO:0040001;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;negative regulation of cell cycle#GO:0045786;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;regulation of cytoskeleton organization#GO:0051493;negative regulation of cellular component organization#GO:0051129;microtubule cytoskeleton organization involved in mitosis#GO:1902850;localization#GO:0051179;negative regulation of cytoskeleton organization#GO:0051494;microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;organelle assembly#GO:0070925;organelle localization#GO:0051640;regulation of signal transduction#GO:0009966;regulation of nuclear division#GO:0051783;regulation of organelle assembly#GO:1902115;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic nuclear division#GO:0007088;establishment of mitotic spindle orientation#GO:0000132;regulation of mitotic sister chromatid separation#GO:0010965;establishment of localization#GO:0051234;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044 microtubule end#GO:1990752;spindle pole#GO:0000922;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;mitotic spindle pole#GO:0097431;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371 MONDO|Ensembl=ENSMODG00000009230.3|UniProtKB=F7EE29 F7EE29 LIF PTHR10633:SF0 LEUKEMIA INHIBITORY FACTOR LEUKEMIA INHIBITORY FACTOR receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function activator activity#GO:0140677 positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of developmental process#GO:0050793;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;regulation of cell differentiation#GO:0045595 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000009648.3|UniProtKB=F6QSG8 F6QSG8 ZWILCH PTHR15995:SF1 PROTEIN ZWILCH HOMOLOG PROTEIN ZWILCH HOMOLOG regulation of chromosome separation#GO:1905818;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cell cycle process#GO:0010564;negative regulation of sister chromatid segregation#GO:0033046;cellular process#GO:0009987;signal transduction#GO:0007165;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of cell cycle#GO:0045786;negative regulation of chromosome segregation#GO:0051985;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;regulation of chromosome segregation#GO:0051983;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;biological regulation#GO:0065007;protein localization to kinetochore#GO:0034501;macromolecule localization#GO:0033036;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic sister chromatid separation#GO:0010965;intracellular protein localization#GO:0008104;mitotic cell cycle process#GO:1903047;regulation of mitotic nuclear division#GO:0007088;negative regulation of chromosome separation#GO:1905819;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cell communication#GO:0007154;localization#GO:0051179;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;negative regulation of chromosome organization#GO:2001251 chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779 MONDO|Ensembl=ENSMODG00000050414.1|UniProtKB=A0A5F8HB39 A0A5F8HB39 PTHR10989:SF22 ANDROGEN-INDUCED PROTEIN 1-RELATED ANDROGEN DEPENDENT TFPI REGULATING PROTEIN hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436 plasma membrane raft#GO:0044853;membrane microdomain#GO:0098857;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane raft#GO:0045121;membrane#GO:0016020;caveola#GO:0005901 MONDO|Ensembl=ENSMODG00000029659.2|UniProtKB=K7DZP7 K7DZP7 LYNX1 PTHR16983:SF27 UPAR/LY6 DOMAIN-CONTAINING PROTEIN LY-6_NEUROTOXIN-LIKE PROTEIN 1 acetylcholine receptor regulator activity#GO:0030548;signaling receptor binding#GO:0005102;acetylcholine receptor inhibitor activity#GO:0030550;binding#GO:0005488;molecular function inhibitor activity#GO:0140678;neurotransmitter receptor regulator activity#GO:0099602;signaling receptor inhibitor activity#GO:0030547;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000019362.3|UniProtKB=H9H7C3 H9H7C3 PTHR12210:SF43 DULLARD PROTEIN PHOSPHATASE CTD SMALL PHOSPHATASE-LIKE PROTEIN catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000002655.4|UniProtKB=F7DI62 F7DI62 WWP2 PTHR11254:SF396 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE E3 UBIQUITIN-PROTEIN LIGASE WWP2 catalytic activity#GO:0003824;transcription factor binding#GO:0008134;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629 regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of monoatomic ion transport#GO:0043269;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of transmembrane transport#GO:0034762;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of localization#GO:0032879;regulation of transport#GO:0051049;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;proteasomal protein catabolic process#GO:0010498;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 MONDO|Ensembl=ENSMODG00000008858.2|UniProtKB=F7CUI4 F7CUI4 LOC100018200 PTHR26450:SF177 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52I1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002022.4|UniProtKB=A0A5F8GRC3 A0A5F8GRC3 PTHR24176:SF14 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 31-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 31 MONDO|Ensembl=ENSMODG00000004828.4|UniProtKB=F6ULW8 F6ULW8 TSPAN2 PTHR19282:SF155 TETRASPANIN TETRASPANIN-2 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004039.2|UniProtKB=F7CMB2 F7CMB2 LENG1 PTHR22093:SF0 LEUKOCYTE RECEPTOR CLUSTER LRC MEMBER 1 LEUKOCYTE RECEPTOR CLUSTER MEMBER 1 MONDO|Ensembl=ENSMODG00000014253.4|UniProtKB=A0A5F8H1R0 A0A5F8H1R0 PTHR23239:SF97 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA1 structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009;organelle organization#GO:0006996;cellular process#GO:0009987;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000012164.3|UniProtKB=F7CYI5 F7CYI5 HYAL3 PTHR11769:SF19 HYALURONIDASE HYALURONIDASE-3 macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;glycosaminoglycan catabolic process#GO:0006027;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycosaminoglycan metabolic process#GO:0030203 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229 glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000012139.4|UniProtKB=F7DI23 F7DI23 PEPD PTHR43226:SF1 XAA-PRO AMINOPEPTIDASE 3 XAA-PRO DIPEPTIDASE peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000029211.2|UniProtKB=K7E5J5 K7E5J5 LOC107648932 PTHR10903:SF199 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000017083.4|UniProtKB=F6VKJ7 F6VKJ7 CD36 PTHR11923:SF12 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 PLATELET GLYCOPROTEIN 4 low-density lipoprotein particle binding#GO:0030169;protein-lipid complex binding#GO:0071814;lipoprotein particle binding#GO:0071813;binding#GO:0005488;protein-containing complex binding#GO:0044877;cargo receptor activity#GO:0038024;low-density lipoprotein particle receptor activity#GO:0005041 endocytosis#GO:0006897;catabolic process#GO:0009056;regulation of biological process#GO:0050789;localization#GO:0051179;fatty acid transport#GO:0015908;protein transport#GO:0015031;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;lipid transport#GO:0006869;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid storage#GO:0019915;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;plasma lipoprotein particle clearance#GO:0034381;import into cell#GO:0098657;intracellular protein localization#GO:0008104;receptor-mediated endocytosis#GO:0006898;metabolic process#GO:0008152;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 plasma membrane raft#GO:0044853;membrane microdomain#GO:0098857;cell surface#GO:0009986;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane raft#GO:0045121;caveola#GO:0005901;membrane#GO:0016020;cell periphery#GO:0071944 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000000573.4|UniProtKB=A0A5F8G979 A0A5F8G979 TOP1 PTHR10290:SF5 DNA TOPOISOMERASE I DNA TOPOISOMERASE 1 nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 DNA topoisomerase#PC00017;DNA metabolism protein#PC00009 DNA replication#P00017>DNA Topisomerase#P00536;DNA replication#P00017>Top#P00530 MONDO|Ensembl=ENSMODG00000004918.4|UniProtKB=F7BH19 F7BH19 ZNF346 PTHR46144:SF5 ZINC FINGER PROTEIN 385B-LIKE ZINC FINGER PROTEIN 346 double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 MONDO|Ensembl=ENSMODG00000050145.1|UniProtKB=A0A5F8G9N1 A0A5F8G9N1 LOC100619493 PTHR26453:SF44 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1330-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012317.4|UniProtKB=F7EIR6 F7EIR6 TSHZ1 PTHR12487:SF6 TEASHIRT-RELATED TEASHIRT HOMOLOG 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000004823.4|UniProtKB=F6UM79 F6UM79 C5orf22 PTHR13225:SF3 MISEXPRESSION SUPPRESSOR OF RAS 6 UPF0489 PROTEIN C5ORF22 MONDO|Ensembl=ENSMODG00000011684.3|UniProtKB=F7GE69 F7GE69 GCH1 PTHR11109:SF11 GTP CYCLOHYDROLASE I GTP CYCLOHYDROLASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824 small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;biosynthetic process#GO:0009058;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Tetrahydrofolate biosynthesis#P02742>GTP cyclohydrolase#P02951 MONDO|Ensembl=ENSMODG00000003283.4|UniProtKB=F7EGA4 F7EGA4 PTHR46110:SF1 HOMEOBOX PROTEIN HMX HOMEOBOX PROTEIN HMX1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000010737.4|UniProtKB=F7G7A0 F7G7A0 SORCS1 PTHR12106:SF8 SORTILIN RELATED VPS10 DOMAIN-CONTAINING RECEPTOR SORCS1 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;post-Golgi vesicle-mediated transport#GO:0006892;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000000574.4|UniProtKB=F6X490 F6X490 GPR37L1 PTHR46216:SF4 PROSAPOSIN RECEPTOR GPR37 FAMILY MEMBER G PROTEIN-COUPLED RECEPTOR 37-LIKE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;positive regulation of MAPK cascade#GO:0043410;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;signaling#GO:0023052;regulation of cell communication#GO:0010646;G protein-coupled receptor signaling pathway#GO:0007186;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of signaling#GO:0023056 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Parkinson disease#P00049>Pael-R#P01229 MONDO|Ensembl=ENSMODG00000040680.1|UniProtKB=A0A5F8GJP0 A0A5F8GJP0 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000018884.4|UniProtKB=K7E2H9 K7E2H9 PTHR10127:SF824 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING MEPRIN A SUBUNIT ALPHA hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000015046.3|UniProtKB=F7FUY5 F7FUY5 LURAP1L PTHR33767:SF1 LEUCINE RICH ADAPTOR PROTEIN 1-LIKE LEUCINE RICH ADAPTOR PROTEIN 1-LIKE regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 MONDO|Ensembl=ENSMODG00000003189.4|UniProtKB=F6VEK6 F6VEK6 MSI1 PTHR48032:SF3 RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 RNA-BINDING PROTEIN MUSASHI HOMOLOG 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000024603.2|UniProtKB=F6PRG5 F6PRG5 TMEM60 PTHR13568:SF4 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 60 MONDO|Ensembl=ENSMODG00000008531.4|UniProtKB=F7DH99 F7DH99 SH3KBP1 PTHR14167:SF6 SH3 DOMAIN-CONTAINING SH3 DOMAIN-CONTAINING KINASE-BINDING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004077.3|UniProtKB=F6VW37 F6VW37 PTHR48068:SF4 TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 9 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;transferase complex#GO:1990234;peptidase complex#GO:1905368;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;nuclear DNA-directed RNA polymerase complex#GO:0055029;chromosome#GO:0005694 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 MONDO|Ensembl=ENSMODG00000004392.4|UniProtKB=F6SVR1 F6SVR1 ALAD PTHR11458:SF0 DELTA-AMINOLEVULINIC ACID DEHYDRATASE DELTA-AMINOLEVULINIC ACID DEHYDRATASE catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 porphyrin-containing compound biosynthetic process#GO:0006779;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;cellular process#GO:0009987 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydratase#PC00091 Heme biosynthesis#P02746>porphobilinogen synthase#P02979 MONDO|Ensembl=ENSMODG00000047806.1|UniProtKB=F6U030 F6U030 PTHR11426:SF247 HISTONE H3 HISTONE H3.3C-LIKE cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;kinetochore assembly#GO:0051382;nuclear division#GO:0000280;organelle localization#GO:0051640;organelle assembly#GO:0070925;organelle fission#GO:0048285;localization#GO:0051179;kinetochore organization#GO:0051383;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 MONDO|Ensembl=ENSMODG00000045778.1|UniProtKB=A0A5F8H379 A0A5F8H379 MFSD4B PTHR23121:SF9 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SOLUTE CARRIER FAMILY 60 MEMBER 2 transporter#PC00227 MONDO|Ensembl=ENSMODG00000029386.2|UniProtKB=K7E3E1 K7E3E1 PTHR14672:SF1 MUCIN-16 MUCIN-16 MONDO|Ensembl=ENSMODG00000007789.4|UniProtKB=F7A990 F7A990 IGSF6 PTHR15297:SF2 IMMUNOGLOBULIN SUPERFAMILY MEMBER 6 IMMUNOGLOBULIN SUPERFAMILY MEMBER 6 immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000017860.4|UniProtKB=F6YIM6 F6YIM6 HDAC2 PTHR10625:SF3 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 2 histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824;deacylase activity#GO:0160215;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043 transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233 Wnt signaling pathway#P00057>Histone deacetylase#P01472;p53 pathway#P00059>HDAC1#P04612 MONDO|Ensembl=ENSMODG00000016669.5|UniProtKB=F7E6Q5 F7E6Q5 PGAP6 PTHR14319:SF7 FIVE-SPAN TRANSMEMBRANE PROTEIN M83 POST-GPI ATTACHMENT TO PROTEINS FACTOR 6 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000003396.3|UniProtKB=F6Z0Y6 F6Z0Y6 MEIS1 PTHR11850:SF126 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN MEIS1 sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 positive regulation of macromolecule metabolic process#GO:0010604;head development#GO:0060322;nervous system development#GO:0007399;embryo development#GO:0009790;embryonic pattern specification#GO:0009880;sensory system development#GO:0048880;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;central nervous system development#GO:0007417;circulatory system development#GO:0072359;cell development#GO:0048468;positive regulation of cell population proliferation#GO:0008284;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;angiogenesis#GO:0001525;eye development#GO:0001654;animal gross anatomical part developmental process#GO:0160108;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;hemopoiesis#GO:0030097;tube development#GO:0035295;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;visual system development#GO:0150063;positive regulation of RNA metabolic process#GO:0051254;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000025023.2|UniProtKB=A0A5F8G2M6 A0A5F8G2M6 PTHR15316:SF1 SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED SPLICING FACTOR 3A SUBUNIT 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U2 snRNP#GO:0005686;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;U2-type prespliceosome#GO:0071004;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000048341.1|UniProtKB=A0A5F8GGL6 A0A5F8GGL6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000495.3|UniProtKB=F6TUS7 F6TUS7 DHX35 PTHR18934:SF136 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX35-RELATED catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000027636.2|UniProtKB=K7DYW6 K7DYW6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000049959.1|UniProtKB=A0A5F8HD94 A0A5F8HD94 PTHR15001:SF3 BETA-DEFENSIN 123-RELATED BETA-DEFENSIN 123 innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376;cell killing#GO:0001906;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;cellular process#GO:0009987 defense/immunity protein#PC00090;antimicrobial response protein#PC00051 MONDO|Ensembl=ENSMODG00000013315.4|UniProtKB=F6YVK0 F6YVK0 GOLGA4 PTHR19327:SF0 GOLGIN GOLGIN SUBFAMILY A MEMBER 4 small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000028632.2|UniProtKB=A0A5F8HBR1 A0A5F8HBR1 LOC130458773 PTHR22574:SF12 FAMILY NOT NAMED GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 5B MONDO|Ensembl=ENSMODG00000009121.4|UniProtKB=F7EYI2 F7EYI2 FIBP PTHR13223:SF2 ACIDIC FIBROBLAST GROWTH FACTOR INTRACELLULAR BINDING PROTEIN ACIDIC FIBROBLAST GROWTH FACTOR INTRACELLULAR-BINDING PROTEIN binding#GO:0005488;growth factor binding#GO:0019838;protein binding#GO:0005515;fibroblast growth factor binding#GO:0017134 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000051344.1|UniProtKB=A0A5F8GEH8 A0A5F8GEH8 ATP5MG PTHR12386:SF12 ATP SYNTHASE SUBUNIT ATP SYNTHASE F(0) COMPLEX SUBUNIT G, MITOCHONDRIAL-RELATED monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;channel activity#GO:0015267;ligase activity#GO:0016874;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261 purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;small molecule metabolic process#GO:0044281;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986 transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;proton-transporting ATP synthase complex#GO:0045259;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000014506.3|UniProtKB=A0A5F8G7X7 A0A5F8G7X7 POU2AF2 PTHR28376:SF1 RGD1562914 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 2 sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000008993.4|UniProtKB=F7BQA5 F7BQA5 G3BP1 PTHR10693:SF21 RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;mRNA binding#GO:0003729;binding#GO:0005488;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;catalytic activity, acting on RNA#GO:0140098 cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cytoplasmic stress granule assembly#GO:0034063;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cellular process#GO:0009987 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000043438.1|UniProtKB=A0A5F8H411 A0A5F8H411 GCA PTHR46735:SF5 CALPAIN, SMALL SUBUNIT 1 A-RELATED GRANCALCIN metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 MONDO|Ensembl=ENSMODG00000019474.4|UniProtKB=F6RBA8 F6RBA8 CCM2L PTHR21642:SF2 CEREBRAL CAVERNOUS MALFORMATIONS PROTEIN 2 HOMOLOG CEREBRAL CAVERNOUS MALFORMATIONS 2 PROTEIN-LIKE developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;heart morphogenesis#GO:0003007;anatomical structure morphogenesis#GO:0009653;heart development#GO:0007507;circulatory system development#GO:0072359;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501 MONDO|Ensembl=ENSMODG00000018271.4|UniProtKB=F6Q735 F6Q735 EAF2 PTHR15970:SF7 ELL-ASSOCIATED FACTOR EAF ELL-ASSOCIATED FACTOR 2 transcription regulator activity#GO:0140110;transcription elongation factor activity#GO:0003711 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 MONDO|Ensembl=ENSMODG00000016883.4|UniProtKB=F6XJH1 F6XJH1 CCT3 PTHR11353:SF24 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT GAMMA metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 chaperonin-containing T-complex#GO:0005832;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein folding chaperone complex#GO:0101031;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829 chaperonin#PC00073 MONDO|Ensembl=ENSMODG00000016892.3|UniProtKB=F6XIM1 F6XIM1 TMEM79 PTHR31004:SF1 TRANSMEMBRANE PROTEIN 79 TRANSMEMBRANE PROTEIN 79 vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;exocytosis#GO:0006887;secretion by cell#GO:0032940;regulated exocytosis#GO:0045055;transport#GO:0006810 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;vacuole#GO:0005773;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;lysosomal membrane#GO:0005765;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794 MONDO|Ensembl=ENSMODG00000009649.4|UniProtKB=F6QSF2 F6QSF2 RPIA PTHR11934:SF0 RIBOSE-5-PHOSPHATE ISOMERASE RIBOSE-5-PHOSPHATE ISOMERASE isomerase activity#GO:0016853;ribose-5-phosphate isomerase activity#GO:0004751;intramolecular oxidoreductase activity#GO:0016860;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824 NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;pentose-phosphate shunt, non-oxidative branch#GO:0009052;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;pentose-phosphate shunt#GO:0006098;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;glyceraldehyde-3-phosphate metabolic process#GO:0019682;nucleotide metabolic process#GO:0009117 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 isomerase#PC00135;metabolite interconversion enzyme#PC00262 Pentose phosphate pathway#P02762>Ribulose 5-P Isomerase#P03071 MONDO|Ensembl=ENSMODG00000051175.1|UniProtKB=A0A5F8HFD6 A0A5F8HFD6 LOC100027267 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014319.5|UniProtKB=F7GC75 F7GC75 MTSS2 PTHR15708:SF8 ACTIN BUNDLING/MISSING IN METASTASIS-RELATED PROTEIN MTSS 2 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289;protein binding#GO:0005515 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;membrane organization#GO:0061024;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000002914.4|UniProtKB=A0A5F8HJ99 A0A5F8HJ99 RANBP2 PTHR23138:SF190 RAN BINDING PROTEIN E3 SUMO-PROTEIN LIGASE RANBP2 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787 protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;protein transport#GO:0015031;nuclear export#GO:0051168;protein import into nucleus#GO:0006606;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020993.4|UniProtKB=A0A5F8G524 A0A5F8G524 CCT8 PTHR11353:SF78 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT THETA protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;protein folding chaperone complex#GO:0101031;chaperonin-containing T-complex#GO:0005832;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 chaperonin#PC00073 MONDO|Ensembl=ENSMODG00000011402.3|UniProtKB=F6S6J6 F6S6J6 CCR9 PTHR10489:SF664 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 9 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023 calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cell communication#GO:0007154;chemotaxis#GO:0006935;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;locomotion#GO:0040011;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000040104.1|UniProtKB=A0A5F8H5S1 A0A5F8H5S1 PTHR38503:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 1 SMALL INTEGRAL MEMBRANE PROTEIN 1 cellular process#GO:0009987;cell development#GO:0048468;homeostatic process#GO:0042592;hemopoiesis#GO:0030097;myeloid cell differentiation#GO:0030099;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;developmental process#GO:0032502;homeostasis of number of cells#GO:0048872;immune system process#GO:0002376;multicellular organismal-level homeostasis#GO:0048871;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;erythrocyte differentiation#GO:0030218 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000025217.3|UniProtKB=F7FKF1 F7FKF1 PTHR11866:SF10 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of transport#GO:0051049;regulation of localization#GO:0032879;system process#GO:0003008;defense response#GO:0006952;regulation of system process#GO:0044057;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;muscle contraction#GO:0006936;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;negative regulation of transport#GO:0051051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of biological process#GO:0050789;muscle system process#GO:0003012;cellular response to stimulus#GO:0051716;regulation of secretion#GO:0051046;cell communication#GO:0007154;regulation of biological quality#GO:0065008;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;inflammatory response#GO:0006954;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836;PI3 kinase pathway#P00048>GPCR#P01204 MONDO|Ensembl=ENSMODG00000018849.4|UniProtKB=F6Z2B1 F6Z2B1 RHAG PTHR11730:SF32 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER RH TYPE A channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;transport#GO:0006810;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000005159.4|UniProtKB=K7E2G1 K7E2G1 PTHR12419:SF58 OTU DOMAIN CONTAINING PROTEIN BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE TRANSFERASE AND DEUBIQUITINASE ALG13 ISOFORM X1 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000015273.4|UniProtKB=F6TMI5 F6TMI5 PTHR12935:SF0 GAMMA-GLUTAMYLCYCLOTRANSFERASE GAMMA-GLUTAMYLCYCLOTRANSFERASE catalytic activity#GO:0003824;lyase activity#GO:0016829 MONDO|Ensembl=ENSMODG00000007756.4|UniProtKB=F7BJC0 F7BJC0 TRIM65 PTHR25465:SF14 B-BOX DOMAIN CONTAINING E3 UBIQUITIN-PROTEIN LIGASE TRIM65 positive regulation of autophagy#GO:0010508;regulation of autophagy#GO:0010506;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of metabolic process#GO:0009893;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000046007.1|UniProtKB=K7E5S3 K7E5S3 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000013313.3|UniProtKB=F6YWA6 F6YWA6 ST6GAL1 PTHR46059:SF2 BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 1 sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule modification#GO:0043412;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000005114.4|UniProtKB=F6YQ84 F6YQ84 CAMK1 PTHR24347:SF197 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;calcium/calmodulin-dependent protein kinase activity#GO:0004683;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of synapse organization#GO:0050807;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of synapse structure or activity#GO:0050803 postsynapse#GO:0098794;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynaptic density#GO:0014069;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000014692.4|UniProtKB=A0A5F8G891 A0A5F8G891 PTHR19944:SF99 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ BETA 1 CHAIN antigen binding#GO:0003823;peptide binding#GO:0042277;binding#GO:0005488;protein-containing complex binding#GO:0044877 regulation of lymphocyte activation#GO:0051249;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;immune system process#GO:0002376;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of T cell activation#GO:0050863;regulation of multicellular organismal process#GO:0051239;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;positive regulation of leukocyte activation#GO:0002696;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell adhesion#GO:0045785;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;positive regulation of cellular process#GO:0048522;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583 vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768 major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000008648.2|UniProtKB=F6PGF5 F6PGF5 STK35L3 PTHR11042:SF169 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of translational initiation#GO:0006446;post-transcriptional regulation of gene expression#GO:0010608 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000010111.3|UniProtKB=F6X3S5 F6X3S5 LOC100012619 PTHR48001:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018455.4|UniProtKB=F7CU66 F7CU66 PIGX PTHR28650:SF1 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS X PROTEIN GPI ALPHA-1,4-MANNOSYLTRANSFERASE I, STABILIZING SUBUNIT MONDO|Ensembl=ENSMODG00000018212.4|UniProtKB=F6PGQ4 F6PGQ4 NR1I2 PTHR24082:SF39 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 2 sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 Angiogenesis#P00005>PAR#P00192 MONDO|Ensembl=ENSMODG00000004371.3|UniProtKB=F6W927 F6W927 GALNT5 PTHR11675:SF130 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 5 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000014249.4|UniProtKB=F6Y1I2 F6Y1I2 RXRB PTHR24083:SF90 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR RXR-BETA signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;hormone-mediated signaling pathway#GO:0009755;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;response to hormone#GO:0009725;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;intracellular receptor signaling pathway#GO:0030522;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000012649.4|UniProtKB=F6WDS9 F6WDS9 LASP1 PTHR46218:SF2 LASP LIM AND SH3 DOMAIN PROTEIN 1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000002714.4|UniProtKB=H9H612 H9H612 GLI3 PTHR45718:SF5 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS TRANSCRIPTION ACTIVATOR GLI3 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cellular process#GO:0009987;signal transduction#GO:0007165;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;smoothened signaling pathway#GO:0007224;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Hedgehog signaling pathway#P00025>Cubitus interruptus repressor#P00687;Hedgehog signaling pathway#P00025>Cubitus interruptus#P00690 MONDO|Ensembl=ENSMODG00000004916.3|UniProtKB=F7BHJ2 F7BHJ2 PTHR12560:SF6 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 ceramide metabolic process#GO:0006672;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000023518.1|UniProtKB=F6Z2L7 F6Z2L7 PAQR8 PTHR20855:SF22 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR BETA transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;lipid binding#GO:0008289;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;steroid binding#GO:0005496 response to lipid#GO:0033993;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to steroid hormone#GO:0048545;response to hormone#GO:0009725;response to endogenous stimulus#GO:0009719 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000014131.4|UniProtKB=A0A5F8HFI1 A0A5F8HFI1 RAPGEF6 PTHR23113:SF249 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 6 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 anatomical structure development#GO:0048856;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;system development#GO:0048731;Ras protein signal transduction#GO:0007265;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000018433.4|UniProtKB=A0A5F8GTU1 A0A5F8GTU1 CACNA1C PTHR45628:SF10 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1C voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261 calcium ion import#GO:0070509;calcium ion transmembrane transport#GO:0070588;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;calcium ion transport#GO:0006816;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234 cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;calcium channel complex#GO:0034704;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 voltage-gated ion channel#PC00241 Nicotine pharmacodynamics pathway#P06587>CACNA#P06600;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Gonadotropin-releasing hormone receptor pathway#P06664>L-type Ca2+#P06812;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096 MONDO|Ensembl=ENSMODG00000027936.2|UniProtKB=K7E5L0 K7E5L0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000025563.3|UniProtKB=F6UI35 F6UI35 FXYD2 PTHR14132:SF3 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106 biological regulation#GO:0065007;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of cellular process#GO:0050794;positive regulation of transport#GO:0051050;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000005682.4|UniProtKB=F6V3J1 F6V3J1 ECPAS PTHR23346:SF19 TRANSLATIONAL ACTIVATOR GCN1-RELATED PROTEASOME ADAPTER AND SCAFFOLD PROTEIN ECM29 macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005616.4|UniProtKB=A0A5F8GRY1 A0A5F8GRY1 ZMYND15 PTHR47085:SF1 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 15 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 15 protein binding#GO:0005515;histone deacetylase binding#GO:0042826;binding#GO:0005488;enzyme binding#GO:0019899 developmental process#GO:0032502;spermatogenesis#GO:0007283;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;male gamete generation#GO:0048232;sexual reproduction#GO:0019953;spermatid development#GO:0007286;regulation of RNA metabolic process#GO:0051252;multicellular organismal reproductive process#GO:0048609;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;spermatid differentiation#GO:0048515;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell differentiation#GO:0030154;gamete generation#GO:0007276 MONDO|Ensembl=ENSMODG00000042551.1|UniProtKB=A0A5F8GT12 A0A5F8GT12 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011476.4|UniProtKB=F6VJZ6 F6VJZ6 SEMA3G PTHR11036:SF20 SEMAPHORIN SEMAPHORIN-3G molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;taxis#GO:0042330;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;neurogenesis#GO:0022008;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axon guidance#GO:0007411;axon development#GO:0061564;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;chemotaxis#GO:0006935;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000021511.4|UniProtKB=F7FSH0 F7FSH0 PSMA8 PTHR11599:SF144 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA-TYPE 8 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 nucleus#GO:0005634;proteasome complex#GO:0000502;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 MONDO|Ensembl=ENSMODG00000036891.1|UniProtKB=A0A5F8H7Z6 A0A5F8H7Z6 LOC100618966 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000029129.2|UniProtKB=K7E013 K7E013 RSPH14 PTHR15599:SF1 RTDR1 RADIAL SPOKE HEAD 14 HOMOLOG MONDO|Ensembl=ENSMODG00000025064.1|UniProtKB=F6SA46 F6SA46 LIG4 PTHR45997:SF4 DNA LIGASE 4 DNA LIGASE 4 DNA binding#GO:0003677;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;ion binding#GO:0043167;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;purine ribonucleotide binding#GO:0032555;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;ligase activity#GO:0016874;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367 DNA damage response#GO:0006974;developmental process#GO:0032502;DNA repair#GO:0006281;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;somatic cell DNA recombination#GO:0016444;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501;system development#GO:0048731;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;somatic diversification of immune receptors#GO:0002200;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;double-strand break repair#GO:0006302;multicellular organism development#GO:0007275;cellular process#GO:0009987;somatic recombination of immunoglobulin gene segments#GO:0016447;response to stress#GO:0006950;nucleotide-excision repair#GO:0006289;gene expression#GO:0010467;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;cellular response to stress#GO:0033554;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;immune system development#GO:0002520;V(D)J recombination#GO:0033151;production of molecular mediator of immune response#GO:0002440;response to stimulus#GO:0050896 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nonhomologous end joining complex#GO:0070419;DNA repair complex#GO:1990391;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000028574.1|UniProtKB=K7E4B1 K7E4B1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000020289.4|UniProtKB=F7C0D8 F7C0D8 OXCT1 PTHR13707:SF23 KETOACID-COENZYME A TRANSFERASE SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000045520.1|UniProtKB=A0A5F8GRN0 A0A5F8GRN0 VN2R591 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000013758.4|UniProtKB=F6TX39 F6TX39 TULP1 PTHR16517:SF12 TUBBY-RELATED TUBBY-RELATED PROTEIN 1 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 localization#GO:0051179;protein localization to organelle#GO:0033365;protein localization to cilium#GO:0061512;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014898.3|UniProtKB=A0A5F8HK94 A0A5F8HK94 EGFL8 PTHR14949:SF27 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 EPIDERMAL GROWTH FACTOR-LIKE PROTEIN 8 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 tube development#GO:0035295;multicellular organismal process#GO:0032501;vasculogenesis#GO:0001570;cellular process#GO:0009987;vasculature development#GO:0001944;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell differentiation#GO:0030154;circulatory system development#GO:0072359;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000023298.2|UniProtKB=F6VSF3 F6VSF3 CITED2 PTHR17045:SF7 MELANOCYTE SPECIFIC GENE RELATED CITED CBP_P300-INTERACTING TRANSACTIVATOR 2 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;transforming growth factor beta receptor signaling pathway#GO:0007179;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;cellular response to growth factor stimulus#GO:0071363;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to transforming growth factor beta#GO:0071559;regulation of RNA metabolic process#GO:0051252;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to growth factor#GO:0070848 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 MONDO|Ensembl=ENSMODG00000050413.1|UniProtKB=K7E2L2 K7E2L2 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000013823.4|UniProtKB=F6SEX9 F6SEX9 HSPA4 PTHR45639:SF6 HSC70CB, ISOFORM G-RELATED HEAT SHOCK 70 KDA PROTEIN 4 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072;Hsp70 family chaperone#PC00027 MONDO|Ensembl=ENSMODG00000000748.4|UniProtKB=F6VPM9 F6VPM9 AGO2 PTHR22891:SF59 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-2 RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;single-stranded RNA binding#GO:0003727;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;pre-miRNA processing#GO:0031054;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulatory ncRNA-mediated gene silencing#GO:0031047;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;RNA metabolic process#GO:0016070;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000001442.4|UniProtKB=A0A5F8HB29 A0A5F8HB29 HDAC9 PTHR10625:SF41 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 9 histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213 chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000009045.4|UniProtKB=A0A5F8GPN9 A0A5F8GPN9 FLT3 PTHR24416:SF356 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515;kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096 positive regulation of cellular process#GO:0048522;cell migration#GO:0016477;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;hemopoiesis#GO:0030097;developmental process#GO:0032502;cellular developmental process#GO:0048869;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;lymphocyte differentiation#GO:0030098;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell activation#GO:0001775;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to cytokine#GO:0034097;response to chemical#GO:0042221;lymphocyte activation#GO:0046649;cell surface receptor signaling pathway#GO:0007166;B cell activation#GO:0042113;positive regulation of cell population proliferation#GO:0008284;leukocyte differentiation#GO:0002521;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;mononuclear cell differentiation#GO:1903131;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;cell development#GO:0048468;immune system process#GO:0002376;response to peptide#GO:1901652 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015976.3|UniProtKB=A0A5F8GHY4 A0A5F8GHY4 CCDC25 PTHR13049:SF2 DUF814-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 25 MONDO|Ensembl=ENSMODG00000051450.1|UniProtKB=A0A5F8HF35 A0A5F8HF35 PODN PTHR45712:SF20 AGAP008170-PA PODOCAN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000011646.4|UniProtKB=A0A5F8GCJ5 A0A5F8GCJ5 CGRRF1 PTHR15379:SF2 CELL GROWTH REGULATOR WITH RING FINGER DOMAIN PROTEIN 1 CELL GROWTH REGULATOR WITH RING FINGER DOMAIN PROTEIN 1 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of growth#GO:0040008;regulation of cellular process#GO:0050794;regulation of cell growth#GO:0001558;regulation of cellular component organization#GO:0051128;negative regulation of cell growth#GO:0030308;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523 MONDO|Ensembl=ENSMODG00000050742.1|UniProtKB=A0A5F8HE95 A0A5F8HE95 PTHR10707:SF11 CYTOCHROME C OXIDASE SUBUNIT IV CYTOCHROME C OXIDASE SUBUNIT 4 ISOFORM 2, MITOCHONDRIAL electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;generation of precursor metabolites and energy#GO:0006091 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 oxidoreductase#PC00176;oxidase#PC00175 MONDO|Ensembl=ENSMODG00000023110.2|UniProtKB=Q2AB91 Q2AB91 MODO-T2R28 PTHR11394:SF58 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 7 transmembrane signaling receptor activity#GO:0004888;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004514.3|UniProtKB=F6V923 F6V923 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000044236.1|UniProtKB=A0A5F8H588 A0A5F8H588 PTHR23267:SF176 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 8-61 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000005407.4|UniProtKB=F6W754 F6W754 PTHR11461:SF186 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B4 peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000011117.4|UniProtKB=F7BB51 F7BB51 PTHR10338:SF119 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H4 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000039008.1|UniProtKB=A0A5F8H7U2 A0A5F8H7U2 NUDT15 PTHR16099:SF5 8-OXO-DGTP DIPHOSPHATES NUDT15 NUCLEOTIDE TRIPHOSPHATE DIPHOSPHATASE NUDT15 MONDO|Ensembl=ENSMODG00000013979.4|UniProtKB=F6R601 F6R601 SLC22A4 PTHR24064:SF222 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;quaternary ammonium group transmembrane transporter activity#GO:0015651 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000009139.4|UniProtKB=F7B105 F7B105 POMP PTHR12828:SF3 PROTEASOME MATURATION PROTEIN UMP1 PROTEASOME MATURATION PROTEIN protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000010582.3|UniProtKB=F7GI08 F7GI08 OVCA2 PTHR48070:SF6 ESTERASE OVCA2 ESTERASE OVCA2 catalytic activity#GO:0003824;hydrolase activity#GO:0016787 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 esterase#PC00097;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000010075.5|UniProtKB=F6ZDY3 F6ZDY3 LOC130457244 PTHR10514:SF51 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 proteolysis#GO:0006508;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;positive regulation of blood pressure#GO:0045777;metabolic process#GO:0008152;system process#GO:0003008;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;peptide hormone processing#GO:0016486;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;biological regulation#GO:0065007;biosynthetic process#GO:0009058;hormone metabolic process#GO:0042445;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;gene expression#GO:0010467 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000048109.1|UniProtKB=A0A5F8H6K4 A0A5F8H6K4 NKX1-2 PTHR24340:SF17 HOMEOBOX PROTEIN NKX NK1 TRANSCRIPTION FACTOR-RELATED PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000020306.3|UniProtKB=F7G7Q4 F7G7Q4 PTGER4 PTHR11866:SF6 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP4 SUBTYPE transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 response to alcohol#GO:0097305;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;negative regulation of response to external stimulus#GO:0032102;response to hormone#GO:0009725;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cellular response to alcohol#GO:0097306;cell communication#GO:0007154;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of response to stimulus#GO:0048583 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 MONDO|Ensembl=ENSMODG00000023991.2|UniProtKB=F7DPV6 F7DPV6 PTHR26450:SF100 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011645.3|UniProtKB=F6TIQ7 F6TIQ7 ANAPC7 PTHR12558:SF36 CELL DIVISION CYCLE 16,23,27 ANAPHASE-PROMOTING COMPLEX SUBUNIT 7 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of organelle organization#GO:0033043;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of cellular component organization#GO:0051128;positive regulation of cellular component organization#GO:0051130;protein modification by small protein conjugation or removal#GO:0070647;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of organelle organization#GO:0010638;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;positive regulation of cell cycle#GO:0045787;regulation of chromosome separation#GO:1905818;regulation of chromosome segregation#GO:0051983;positive regulation of mitotic nuclear division#GO:0045840;metabolic process#GO:0008152;cell division#GO:0051301;regulation of cell cycle phase transition#GO:1901987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular process#GO:0050794;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of nuclear division#GO:0051783;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of chromosome organization#GO:0033044;regulation of mitotic nuclear division#GO:0007088;positive regulation of mitotic cell cycle#GO:0045931;macromolecule metabolic process#GO:0043170;regulation of mitotic sister chromatid separation#GO:0010965 organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000004858.3|UniProtKB=F6TP23 F6TP23 PTHR35252:SF1 RETINITIS PIGMENTOSA 9 PROTEIN RETINITIS PIGMENTOSA 9 PROTEIN MONDO|Ensembl=ENSMODG00000004248.4|UniProtKB=F6UB24 F6UB24 MCRS1 PTHR13233:SF0 MICROSPHERULE PROTEIN 1 MICROSPHERULE PROTEIN 1 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893 chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;NSL complex#GO:0044545 MONDO|Ensembl=ENSMODG00000037759.1|UniProtKB=A0A5F8GIH7 A0A5F8GIH7 PTHR11486:SF41 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 22 receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;developmental process#GO:0032502;response to fibroblast growth factor#GO:0071774;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000004182.5|UniProtKB=A0A5F8H4X7 A0A5F8H4X7 SGSM1 PTHR22957:SF187 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000016597.4|UniProtKB=H9H706 H9H706 PRADC1 PTHR22702:SF1 PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000014350.4|UniProtKB=F6U5M3 F6U5M3 PFKFB4 PTHR10606:SF14 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE 4 phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydrolase activity#GO:0016787;sugar-phosphatase activity#GO:0050308;phosphoric ester hydrolase activity#GO:0042578;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;kinase activity#GO:0016301;phosphatase activity#GO:0016791;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate kinase activity#GO:0019200 organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 hydrolase#PC00121;carbohydrate phosphatase#PC00066;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000011089.4|UniProtKB=F7E5G9 F7E5G9 GOSR2 PTHR21230:SF99 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED GOLGI SNAP RECEPTOR COMPLEX MEMBER 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;SNAP receptor activity#GO:0005484;protein binding#GO:0005515 localization#GO:0051179;cellular component organization#GO:0016043;intra-Golgi vesicle-mediated transport#GO:0006891;vesicle fusion#GO:0006906;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 membrane traffic protein#PC00150;SNARE protein#PC00034 MONDO|Ensembl=ENSMODG00000027492.2|UniProtKB=K7E2R7 K7E2R7 PTHR10424:SF72 VIRAL ENVELOPE PROTEIN BC035947 PROTEIN-RELATED cell differentiation#GO:0030154;muscle structure development#GO:0061061;myoblast fusion#GO:0007520;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;syncytium formation by cell-cell fusion#GO:0000768;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;striated muscle cell differentiation#GO:0051146;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007123.4|UniProtKB=A0A5F8H051 A0A5F8H051 CPSF6 PTHR23204:SF3 CLEAVAGE AND POLYADENYLATION SPECIFIC FACTOR CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 6 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 RNA processing factor#PC00147;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000016563.3|UniProtKB=A0A5F8H6V3 A0A5F8H6V3 POLR3H PTHR12709:SF1 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC8 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383 nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000004603.3|UniProtKB=F6Y4N9 F6Y4N9 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000004961.4|UniProtKB=F7FL90 F7FL90 MOGS PTHR10412:SF11 MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE alpha-glucosidase activity#GO:0090599;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;glucosidase activity#GO:0015926 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 glucosidase#PC00108;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000003346.4|UniProtKB=F7CTI6 F7CTI6 TMEFF1 PTHR21632:SF3 REGULATORY PROTEIN ZESTE TOMOREGULIN-1 molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000002764.3|UniProtKB=F6YH14 F6YH14 SULT1C2 PTHR11783:SF73 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1C2 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000013793.3|UniProtKB=F6TE40 F6TE40 MRPL55 PTHR34095:SF1 39S RIBOSOMAL PROTEIN L55, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML55 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000006983.4|UniProtKB=F6QAS8 F6QAS8 KLHL35 PTHR24412:SF187 KELCH PROTEIN KELCH-LIKE PROTEIN 35 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000001947.4|UniProtKB=F6VJT5 F6VJT5 LOC100016550 PTHR21357:SF2 FAM172 FAMILY PROTEIN HOMOLOG CG10038 PROTEIN ARB2BP-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulatory ncRNA-mediated heterochromatin formation#GO:0031048;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;cellular component assembly#GO:0022607;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000013236.3|UniProtKB=F7ECW8 F7ECW8 DRC12 PTHR28656:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 153 DYNEIN REGULATORY COMPLEX PROTEIN 12 MONDO|Ensembl=ENSMODG00000029479.2|UniProtKB=K7E6E0 K7E6E0 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015956.3|UniProtKB=A0A5F8HDF2 A0A5F8HDF2 FAM43B PTHR11232:SF34 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PROTEIN FAM43B signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 circulatory system development#GO:0072359;multicellular organismal process#GO:0032501;system development#GO:0048731;vasculature development#GO:0001944;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000038178.1|UniProtKB=A0A5F8G923 A0A5F8G923 VN2R572 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007836.4|UniProtKB=F7ETD3 F7ETD3 IPO7 PTHR10997:SF27 IMPORTIN-7, 8, 11 IMPORTIN-7 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein localization to organelle#GO:0033365;cellular localization#GO:0051641;localization#GO:0051179;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913 organelle envelope#GO:0031967;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 MONDO|Ensembl=ENSMODG00000016629.4|UniProtKB=F6YML4 F6YML4 PTHR24027:SF78 CADHERIN-23 CADHERIN-LIKE PROTEIN 26 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155;cell migration#GO:0016477;cell motility#GO:0048870 extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 MONDO|Ensembl=ENSMODG00000005301.3|UniProtKB=F7DMK5 F7DMK5 PTHR10239:SF28 ISTHMIN-2 ISTHMIN-2 MONDO|Ensembl=ENSMODG00000021443.4|UniProtKB=F7BT67 F7BT67 PTHR24073:SF588 DRAB5-RELATED RAS-RELATED PROTEIN RAB-31 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 localization#GO:0051179;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000001279.4|UniProtKB=F7CIN4 F7CIN4 FGG PTHR19143:SF338 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN GAMMA CHAIN response to stress#GO:0006950;cell-cell adhesion#GO:0098609;response to wounding#GO:0009611;coagulation#GO:0050817;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;biological regulation#GO:0065007;homotypic cell-cell adhesion#GO:0034109;metabolic process#GO:0008152;platelet aggregation#GO:0070527;platelet activation#GO:0030168;macromolecule metabolic process#GO:0043170;blood coagulation#GO:0007596;hemostasis#GO:0007599;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;blood coagulation, fibrin clot formation#GO:0072378;cell activation#GO:0001775;cell-substrate adhesion#GO:0031589;protein activation cascade#GO:0072376;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;wound healing#GO:0042060 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Plasminogen activating cascade#P00050>Fibrin#P01253;Blood coagulation#P00011>Fibrin polymer cross-linked#P00443;Blood coagulation#P00011>Fibrinogen#P00406;Blood coagulation#P00011>Fibrin monomer#P00418 MONDO|Ensembl=ENSMODG00000040055.1|UniProtKB=F7BLS2 F7BLS2 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005656.5|UniProtKB=F6VL57 F6VL57 GRIN3B PTHR18966:SF364 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 3B transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;regulation of trans-synaptic signaling#GO:0099177;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;glutamate receptor signaling pathway#GO:0007215;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537 cell junction#GO:0030054;synaptic membrane#GO:0097060;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794 transmembrane signal receptor#PC00197 Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Ionotropic glutamate receptor pathway#P00037>NR3#P01009;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071 MONDO|Ensembl=ENSMODG00000023910.1|UniProtKB=F7F9V8 F7F9V8 PTHR43986:SF1 ELONGATION FACTOR 1-GAMMA ELONGATION FACTOR 1-GAMMA biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000010862.4|UniProtKB=F7AR16 F7AR16 ZFAND4 PTHR46728:SF1 AN1-TYPE ZINC FINGER PROTEIN 4 AN1-TYPE ZINC FINGER PROTEIN 4 MONDO|Ensembl=ENSMODG00000050577.1|UniProtKB=A0A5F8GFT0 A0A5F8GFT0 BRME1 PTHR14583:SF0 UNCHARACTERIZED PROTEIN C19ORF57 FAMILY MEMBER BREAK REPAIR MEIOTIC RECOMBINASE RECRUITMENT FACTOR 1 MONDO|Ensembl=ENSMODG00000005441.3|UniProtKB=F7CH01 F7CH01 OXT PTHR11681:SF16 NEUROPHYSIN MESOTOCIN_NEUROPHYSIN I PREPROPEPTIDE neuropeptide hormone activity#GO:0005184;hormone activity#GO:0005179;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 peptide hormone#PC00179;neuropeptide#PC00162 MONDO|Ensembl=ENSMODG00000017313.4|UniProtKB=A0A5F8HAN7 A0A5F8HAN7 PTHR11430:SF13 LIPOCALIN NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000024499.3|UniProtKB=F7G7R8 F7G7R8 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018011.3|UniProtKB=A0A5F8GU83 A0A5F8GU83 NTF3 PTHR11589:SF4 NERVE GROWTH FACTOR NGF -RELATED NEUROTROPHIN-3 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;negative regulation of apoptotic process#GO:0043066;multicellular organismal process#GO:0032501;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;cellular component organization#GO:0016043;cellular response to growth factor stimulus#GO:0071363;neuron development#GO:0048666;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;regulation of trans-synaptic signaling#GO:0099177;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;neuron projection development#GO:0031175;regulation of neuron apoptotic process#GO:0043523;negative regulation of neuron apoptotic process#GO:0043524;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular response to nerve growth factor stimulus#GO:1990090;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;plasma membrane bounded cell projection morphogenesis#GO:0120039 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cytoplasm#GO:0005737;endomembrane system#GO:0012505;transport vesicle#GO:0030133;presynapse#GO:0098793;secretory vesicle#GO:0099503 growth factor#PC00112;neurotrophic factor#PC00163 MONDO|Ensembl=ENSMODG00000025541.2|UniProtKB=F6UJB4 F6UJB4 PTHR48018:SF28 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8K3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002139.4|UniProtKB=F6YF70 F6YF70 PTHR10155:SF2 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT GAMMA enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 cell surface receptor signaling pathway#GO:0007166;cellular response to insulin stimulus#GO:0032869;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;insulin receptor signaling pathway#GO:0008286;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;cellular response to peptide hormone stimulus#GO:0071375;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719 extrinsic component of membrane#GO:0019898;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane#GO:0016020 kinase modulator#PC00140 Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;PDGF signaling pathway#P00047>PI3K#P01168;Angiogenesis#P00005>PI3K#P00236;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;PI3 kinase pathway#P00048>p85#P01202;Integrin signalling pathway#P00034>PI3K#P00936;VEGF signaling pathway#P00056>PI3K#P01413;Axon guidance mediated by netrin#P00009>PI3K#P00363;T cell activation#P00053>PI3K#P01322;p53 pathway feedback loops 2#P04398>PI3K#P04661 MONDO|Ensembl=ENSMODG00000027465.2|UniProtKB=K7E4H7 K7E4H7 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000013209.4|UniProtKB=F7EWG1 F7EWG1 PTHR22588:SF5 VWFA DOMAIN-CONTAINING PROTEIN COLLAGEN ALPHA-6(VI) CHAIN external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000038927.1|UniProtKB=A0A5F8GDZ0 A0A5F8GDZ0 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000039382.1|UniProtKB=A0A5F8GGS6 A0A5F8GGS6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000028179.1|UniProtKB=K7E138 K7E138 PTHR24409:SF447 ZINC FINGER PROTEIN 142 NOVEL ZINC FINGER PROTEIN ISOFORM X1 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002551.4|UniProtKB=F7ALU7 F7ALU7 GIPC1 PTHR12259:SF4 RGS-GAIP INTERACTING PROTEIN GIPC PDZ DOMAIN-CONTAINING PROTEIN GIPC1 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019807.4|UniProtKB=A0A5F8GBL8 A0A5F8GBL8 ACAP2 PTHR23180:SF241 CENTAURIN/ARF ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 actin filament-based process#GO:0030029;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036 intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000005219.4|UniProtKB=F6ZD15 F6ZD15 CAMTA2 PTHR23335:SF9 CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 2 transcription coregulator activity#GO:0003712;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000042796.1|UniProtKB=A0A5F8GUK4 A0A5F8GUK4 NXPH1 PTHR17103:SF13 NEUREXOPHILIN NEUREXOPHILIN-1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;GABA-ergic synapse#GO:0098982 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000003877.2|UniProtKB=A0A5F8HKL0 A0A5F8HKL0 PTHR12595:SF0 POS9-ACTIVATING FACTOR FAP7-RELATED ADENYLATE KINASE ISOENZYME 6 kinase activity#GO:0016301;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleobase-containing compound kinase activity#GO:0019205;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000006837.3|UniProtKB=F6PFY9 F6PFY9 CACTIN PTHR21737:SF6 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 SPLICING FACTOR CACTIN RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of immune response#GO:0050776;negative regulation of immune response#GO:0050777;regulation of defense response#GO:0031347;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;regulation of response to biotic stimulus#GO:0002831;negative regulation of defense response#GO:0031348;regulation of immune system process#GO:0002682;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of innate immune response#GO:0045088;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of immune system process#GO:0002683;biosynthetic process#GO:0009058;negative regulation of response to stimulus#GO:0048585;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of response to external stimulus#GO:0032102;RNA processing#GO:0006396;negative regulation of innate immune response#GO:0045824;regulation of response to external stimulus#GO:0032101;gene expression#GO:0010467;cellular process#GO:0009987;mRNA processing#GO:0006397 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;spliceosomal complex#GO:0005681;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000043350.1|UniProtKB=A0A5F8GY91 A0A5F8GY91 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000011313.4|UniProtKB=F7C6S5 F7C6S5 PSD PTHR10663:SF334 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 1 ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;ruffle#GO:0001726;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000014538.4|UniProtKB=F7E9F3 F7E9F3 CPA1 PTHR11705:SF94 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A1 catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000003561.2|UniProtKB=F7GBA7 F7GBA7 C1D PTHR15341:SF3 SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D DNA binding#GO:0003677;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000009674.4|UniProtKB=F6SH52 F6SH52 PATZ1 PTHR24399:SF15 ZINC FINGER AND BTB DOMAIN-CONTAINING POZ-, AT HOOK-, AND ZINC FINGER-CONTAINING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217 regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000008001.4|UniProtKB=F7CLK9 F7CLK9 CNKSR2 PTHR12844:SF21 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;postsynapse organization#GO:0099173;signaling#GO:0023052;synapse organization#GO:0050808;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;postsynaptic specialization organization#GO:0099084;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840 synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000016461.4|UniProtKB=F7BTN7 F7BTN7 CASP16 PTHR22576:SF41 MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE CASPASE 14, APOPTOSIS-RELATED CYSTEINE PEPTIDASE regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000008753.4|UniProtKB=F6TLP1 F6TLP1 CDK8 PTHR24056:SF243 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 8 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911;mediator complex#GO:0016592;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000050075.1|UniProtKB=A0A5F8GUH0 A0A5F8GUH0 PTHR48614:SF3 AT03386P MAPK-REGULATED COREPRESSOR-INTERACTING PROTEIN 1 MONDO|Ensembl=ENSMODG00000007474.4|UniProtKB=F7CRI9 F7CRI9 COPS8 PTHR13339:SF2 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005520.2|UniProtKB=F7G5A0 F7G5A0 CIPC PTHR34648:SF1 CLOCK-INTERACTING PACEMAKER CLOCK-INTERACTING PACEMAKER negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000025379.1|UniProtKB=F6ZAA7 F6ZAA7 CLDN17 PTHR12002:SF75 CLAUDIN CLAUDIN-17 transporter activity#GO:0005215;paracellular tight junction channel activity#GO:0160187 cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cell-cell junction assembly#GO:0007043;transport#GO:0006810;cell-cell junction organization#GO:0045216;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;paracellular transport#GO:0160184;localization#GO:0051179 apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000017586.4|UniProtKB=A0A5F8HDZ2 A0A5F8HDZ2 PTHR15934:SF6 RNA 2',3'-CYCLIC PHOSPHODIESTERASE A-KINASE ANCHOR PROTEIN 7 ISOFORM GAMMA protein kinase A regulatory subunit binding#GO:0034237;binding#GO:0005488;protein kinase A binding#GO:0051018;protein binding#GO:0005515 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000037505.1|UniProtKB=A0A5F8H255 A0A5F8H255 PTHR10078:SF27 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-1 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;response to lipopolysaccharide#GO:0032496;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;cellular response to cytokine stimulus#GO:0071345;response to peptide#GO:1901652;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to oxygen-containing compound#GO:1901700;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955;cellular response to molecule of bacterial origin#GO:0071219;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to bacterium#GO:0009617;cytokine-mediated signaling pathway#GO:0019221;inflammatory response#GO:0006954 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interleukin superfamily#PC00128;cytokine#PC00083;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000010452.4|UniProtKB=F7F7S7 F7F7S7 ANKDD1A PTHR24125:SF0 ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1A MONDO|Ensembl=ENSMODG00000021087.4|UniProtKB=A0A5F8GYB6 A0A5F8GYB6 KDM6A PTHR14017:SF9 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 6A transcription cis-regulatory region binding#GO:0000976;chromatin binding#GO:0003682;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;dioxygenase activity#GO:0051213;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;chromatin DNA binding#GO:0031490;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;sequence-specific double-stranded DNA binding#GO:1990837;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;binding#GO:0005488;histone modifying activity#GO:0140993;transcription regulatory region nucleic acid binding#GO:0001067;histone demethylase activity#GO:0032452;sequence-specific DNA binding#GO:0043565;protein demethylase activity#GO:0140457;demethylase activity#GO:0032451 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;multicellular organismal process#GO:0032501;heart development#GO:0007507;biological regulation#GO:0065007;developmental process#GO:0032502;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000042731.1|UniProtKB=A0A5F8H8U8 A0A5F8H8U8 PTHR45935:SF10 PROTEIN ZBED8-RELATED SCAN DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000015109.4|UniProtKB=F7F360 F7F360 AARSD1 PTHR43462:SF1 ALANYL-TRNA EDITING PROTEIN ALANYL-TRNA EDITING PROTEIN AARSD1 carboxylic ester hydrolase activity#GO:0052689;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;deacylase activity#GO:0160215;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098 biological regulation#GO:0065007;regulation of biological quality#GO:0065008 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000043753.1|UniProtKB=F7A138 F7A138 LOC100020596 PTHR26450:SF392 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040001.1|UniProtKB=A0A5F8H419 A0A5F8H419 PTHR11073:SF11 CALRETICULIN AND CALNEXIN CALNEXIN small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein folding#GO:0006457;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000038459.1|UniProtKB=A0A5F8HF11 A0A5F8HF11 LOC100618856 PTHR48018:SF170 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5D3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000710.4|UniProtKB=F6WL84 F6WL84 RPE65 PTHR10543:SF57 BETA-CAROTENE DIOXYGENASE RETINOID ISOMEROHYDROLASE carboxylic ester hydrolase activity#GO:0052689;dioxygenase activity#GO:0051213;hydrolase activity#GO:0016787;cis-trans isomerase activity#GO:0016859;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;oxidoreductase activity#GO:0016491;isomerase activity#GO:0016853 lipid metabolic process#GO:0006629;pigment biosynthetic process#GO:0046148;metabolic process#GO:0008152;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;tetraterpenoid biosynthetic process#GO:0016109;lipid catabolic process#GO:0016042;pigment metabolic process#GO:0042440;xanthophyll biosynthetic process#GO:0016123;biosynthetic process#GO:0009058;terpenoid biosynthetic process#GO:0016114;lipid biosynthetic process#GO:0008610;isoprenoid biosynthetic process#GO:0008299;terpenoid metabolic process#GO:0006721;olefinic compound metabolic process#GO:0120254;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;carotenoid metabolic process#GO:0016116;carotenoid biosynthetic process#GO:0016117;catabolic process#GO:0009056 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000004388.4|UniProtKB=F6SVU9 F6SVU9 TCHP PTHR31183:SF2 TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN FAMILY MEMBER TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN cellular process#GO:0009987;cell death#GO:0008219;apoptotic process#GO:0006915;programmed cell death#GO:0012501 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000013438.3|UniProtKB=F7GIL5 F7GIL5 FBXO27 PTHR12125:SF9 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 27 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000021302.4|UniProtKB=F7G3S7 F7G3S7 ACTL6A PTHR11937:SF487 ACTIN ACTIN-LIKE PROTEIN 6A structural molecule activity#GO:0005198;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;chromatin binding#GO:0003682 animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219 H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514 actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000017228.4|UniProtKB=A0A5F8HHY8 A0A5F8HHY8 BMX PTHR24418:SF91 TYROSINE-PROTEIN KINASE CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX non-membrane spanning protein tyrosine kinase activity#GO:0004715;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 MONDO|Ensembl=ENSMODG00000019854.4|UniProtKB=F6RRK5 F6RRK5 API5 PTHR12758:SF25 APOPTOSIS INHIBITOR 5-RELATED APOPTOSIS INHIBITOR 5 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000038776.1|UniProtKB=A0A5F8HEG2 A0A5F8HEG2 PTHR33166:SF1 GAG_P30 DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000016952.3|UniProtKB=F6V6A8 F6V6A8 PTHR24256:SF521 TRYPTASE-RELATED TRYPTASE DELTA catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000008883.3|UniProtKB=F7CA90 F7CA90 PRSS55 PTHR24253:SF8 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 52 serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000019485.3|UniProtKB=F6WAA9 F6WAA9 PTHR11829:SF370 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN S1 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000025164.2|UniProtKB=F7G8E3 F7G8E3 GPR45 PTHR24245:SF4 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 45-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 MONDO|Ensembl=ENSMODG00000038800.1|UniProtKB=A0A5F8H9X0 A0A5F8H9X0 PTHR11753:SF58 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP COMPLEX MU_SIGMA SUBUNIT DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150;vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000050605.1|UniProtKB=A0A5F8GQZ1 A0A5F8GQZ1 PTHR48018:SF170 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5D3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005609.3|UniProtKB=F7CZS5 F7CZS5 ABHD4 PTHR42886:SF21 RE40534P-RELATED (LYSO)-N-ACYLPHOSPHATIDYLETHANOLAMINE LIPASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;transferase activity#GO:0016740;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;acyltransferase activity#GO:0016746;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622 organophosphate biosynthetic process#GO:0090407;homeostatic process#GO:0042592;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;lipid homeostasis#GO:0055088;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycerophospholipid biosynthetic process#GO:0046474;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000008962.3|UniProtKB=F7G2D6 F7G2D6 MTIF3 PTHR10938:SF9 TRANSLATION INITIATION FACTOR IF-3 TRANSLATION INITIATION FACTOR IF-3, MITOCHONDRIAL translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000018548.4|UniProtKB=A0A5F8H836 A0A5F8H836 KCNQ5 PTHR47735:SF8 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 5 voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 voltage-gated ion channel#PC00241;transporter#PC00227 MONDO|Ensembl=ENSMODG00000017988.4|UniProtKB=F7B8I0 F7B8I0 A2M PTHR11412:SF165 MACROGLOBULIN / COMPLEMENT ALPHA-2-MACROGLOBULIN peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 response to stress#GO:0006950;inflammatory response#GO:0006954;response to stimulus#GO:0050896;defense response#GO:0006952 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494 protease inhibitor#PC00191 Blood coagulation#P00011>alpha2-macroglobulin#P00427 MONDO|Ensembl=ENSMODG00000029342.2|UniProtKB=K7E0E4 K7E0E4 PTHR13163:SF2 SPINAL CORD EXPRESSION PROTEIN 4 TRANSMEMBRANE PROTEIN 35B chaperone-mediated protein complex assembly#GO:0051131;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;biological regulation#GO:0065007;cellular component assembly#GO:0022607 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000039260.1|UniProtKB=F6R3F5 F6R3F5 LOC100022203 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000050821.1|UniProtKB=A0A5F8GZT4 A0A5F8GZT4 PTHR11716:SF4 PHOSPHOLIPASE A2 FAMILY MEMBER GROUP 10 SECRETORY PHOSPHOLIPASE A2 glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;lipid binding#GO:0008289;catalytic activity#GO:0003824;phospholipid binding#GO:0005543;hydrolase activity, acting on ester bonds#GO:0016788;small molecule binding#GO:0036094;lipase activity#GO:0016298;ion binding#GO:0043167;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylcholine metabolic process#GO:0046470;phosphatidylglycerol metabolic process#GO:0046471;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000025703.3|UniProtKB=F6TIH7 F6TIH7 PTHR13483:SF3 BOX C_D SNORNA PROTEIN 1-RELATED BOX C_D SNORNA PROTEIN 1 protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular component assembly#GO:0022607;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000016809.5|UniProtKB=A0A5F8G478 A0A5F8G478 PTHR21678:SF6 GROWTH INHIBITION AND DIFFERENTIATION RELATED PROTEIN 88 R3H AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000003902.5|UniProtKB=F7D7U6 F7D7U6 GPR27 PTHR19268:SF8 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 27-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000007997.3|UniProtKB=A0A5F8GN45 A0A5F8GN45 LTA4H PTHR45726:SF7 LEUKOTRIENE A-4 HYDROLASE LEUKOTRIENE A-4 HYDROLASE catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;peptidase activity#GO:0008233;ether hydrolase activity#GO:0016803;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;peptide metabolic process#GO:0006518;carboxylic acid metabolic process#GO:0019752;peptide catabolic process#GO:0043171;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;icosanoid metabolic process#GO:0006690;biosynthetic process#GO:0009058;icosanoid biosynthetic process#GO:0046456 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000008310.4|UniProtKB=F7FGX3 F7FGX3 TTC34 PTHR44874:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 34 TETRATRICOPEPTIDE REPEAT PROTEIN 34 MONDO|Ensembl=ENSMODG00000050157.1|UniProtKB=A0A5F8GH78 A0A5F8GH78 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000005589.4|UniProtKB=F7DJV5 F7DJV5 PTHR47161:SF1 LYMPHOID-SPECIFIC HELICASE LYMPHOID-SPECIFIC HELICASE ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;protein-macromolecule adaptor activity#GO:0030674;chromatin-protein adaptor activity#GO:0140463;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;molecular adaptor activity#GO:0060090;catalytic activity, acting on a nucleic acid#GO:0140640 response to stress#GO:0006950;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;constitutive heterochromatin formation#GO:0140719;double-strand break repair#GO:0006302;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;double-strand break repair via homologous recombination#GO:0000724;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular response to stress#GO:0033554;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;DNA damage response#GO:0006974;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;recombinational repair#GO:0000725 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;heterochromatin#GO:0000792;membraneless organelle#GO:0043228 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000018413.3|UniProtKB=F6XV15 F6XV15 FBXL14 PTHR13318:SF273 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 14 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 transferase complex#GO:1990234;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000025685.2|UniProtKB=F6U018 F6U018 LOC100011472 PTHR15333:SF2 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 5 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 5 MONDO|Ensembl=ENSMODG00000018665.4|UniProtKB=H9H769 H9H769 PTHR19302:SF13 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 2 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;reproductive process#GO:0022414;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000005687.3|UniProtKB=F6V3D4 F6V3D4 SEC23B PTHR11141:SF10 PROTEIN TRANSPORT PROTEIN SEC23 PROTEIN TRANSPORT PROTEIN SEC23B enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 cellular component organization#GO:0016043;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;ER to Golgi transport vesicle membrane#GO:0012507;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;cytoplasm#GO:0005737;vesicle coat#GO:0030120;intracellular organelle#GO:0043229;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000009496.4|UniProtKB=A0A5F8G8S8 A0A5F8G8S8 NCSTN PTHR21092:SF1 NICASTRIN NICASTRIN biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 Alzheimer disease-presenilin pathway#P00004>Nicastrin#P00115;Notch signaling pathway#P00045>Nicastrin#P01108;Alzheimer disease-amyloid secretase pathway#P00003>Nicastrin#P00095 MONDO|Ensembl=ENSMODG00000041089.1|UniProtKB=A0A5F8G6Q5 A0A5F8G6Q5 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013479.4|UniProtKB=F7FM65 F7FM65 MTCH1 PTHR10780:SF3 MITOCHONDRIAL CARRIER HOMOLOG MITOCHONDRIAL CARRIER HOMOLOG 1 membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein insertion into mitochondrial outer membrane#GO:0045040;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of biological process#GO:0050789;protein localization to mitochondrion#GO:0070585;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of apoptotic process#GO:0042981;membrane organization#GO:0061024;biological regulation#GO:0065007;mitochondrion organization#GO:0007005;protein insertion into membrane#GO:0051205;establishment of protein localization#GO:0045184;positive regulation of biological process#GO:0048518;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150 intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000006522.3|UniProtKB=Q9XT87 Q9XT87 LDHA PTHR43128:SF10 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A CHAIN oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 energy derivation by oxidation of organic compounds#GO:0015980;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;monocarboxylic acid catabolic process#GO:0072329;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000001939.4|UniProtKB=F7C6Q0 F7C6Q0 CTSE PTHR47966:SF26 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED CATHEPSIN E endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;antigen processing and presentation#GO:0019882;protein metabolic process#GO:0019538;proteolysis#GO:0006508;immune system process#GO:0002376;metabolic process#GO:0008152 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 protease#PC00190;aspartic protease#PC00053 MONDO|Ensembl=ENSMODG00000003002.4|UniProtKB=F6Q3R3 F6Q3R3 NME7 PTHR43109:SF2 NUCLEOSIDE DIPHOSPHATE KINASE 7 NUCLEOSIDE DIPHOSPHATE KINASE 7 supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;cytoplasmic microtubule#GO:0005881;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630 transferase#PC00220;kinase#PC00137 De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo purine biosynthesis#P02738>dADP kinase#P02907 MONDO|Ensembl=ENSMODG00000012914.4|UniProtKB=F7GCF3 F7GCF3 ABCC12 PTHR24223:SF10 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 12 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000008771.4|UniProtKB=F6RGK9 F6RGK9 SNAPC1 PTHR15131:SF3 SMALL NUCLEAR RNA ACTIVATING COMPLEX, POLYPEPTIDE 1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 1 binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677 transcription by RNA polymerase III#GO:0006383;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;snRNA transcription#GO:0009301;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA transcription by RNA polymerase III#GO:0042796;snRNA metabolic process#GO:0016073;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000000650.4|UniProtKB=A0A5F8GG79 A0A5F8GG79 C1QTNF6 PTHR22923:SF70 CEREBELLIN-RELATED COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 6 pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000044425.1|UniProtKB=F6RPI6 F6RPI6 LOC100020937 PTHR48018:SF170 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5D3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016382.2|UniProtKB=F7EQQ4 F7EQQ4 ADCY9 PTHR45627:SF8 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 9 catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016 organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;ribonucleotide metabolic process#GO:0009259;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;cyclic nucleotide biosynthetic process#GO:0009190;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 adenylate cyclase#PC00043 GABA-B receptor II signaling#P05731>AC#P05760;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 MONDO|Ensembl=ENSMODG00000010444.4|UniProtKB=F6YSA8 F6YSA8 GPAA1 PTHR13304:SF0 GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN GPI-ANCHOR TRANSAMIDASE COMPONENT GPAA1 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;GPI anchored protein biosynthesis#GO:0180046;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;cytoplasm#GO:0005737;caspase complex#GO:0008303;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000014571.3|UniProtKB=F7AST0 F7AST0 BTD PTHR10609:SF14 BIOTINIDASE-RELATED BIOTINIDASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;biotin metabolic process#GO:0006768 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000045059.1|UniProtKB=A0A5F8HBB0 A0A5F8HBB0 GLRB PTHR18945:SF29 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT BETA extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;chloride channel activity#GO:0005254;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;monoatomic anion transmembrane transport#GO:0098656;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization#GO:0051234;chloride transport#GO:0006821;transport#GO:0006810 postsynaptic specialization#GO:0099572;organelle#GO:0043226;plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944;cell junction#GO:0030054;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;synaptic membrane#GO:0097060 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000018983.4|UniProtKB=F7FP29 F7FP29 PTK7 PTHR45080:SF21 CONTACTIN 5 INACTIVE TYROSINE-PROTEIN KINASE 7 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;cellular component organization#GO:0016043 axon#GO:0030424;anchoring junction#GO:0070161;cell junction#GO:0030054;neuron projection#GO:0043005;cell body#GO:0044297;cell-cell junction#GO:0005911;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000006973.4|UniProtKB=F6QUP0 F6QUP0 SHCBP1L PTHR14695:SF7 SHC SH2-DOMAIN BINDING PROTEIN 1-RELATED TESTICULAR SPINDLE-ASSOCIATED PROTEIN SHCBP1L cellular process#GO:0009987;organelle organization#GO:0006996;male meiotic nuclear division#GO:0007140;male gamete generation#GO:0048232;spermatogenesis#GO:0007283;developmental process#GO:0032502;meiotic cell cycle#GO:0051321;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;cell cycle process#GO:0022402;cell division#GO:0051301;cell cycle#GO:0007049;cellular component organization#GO:0016043;developmental process involved in reproduction#GO:0003006;meiotic cell cycle process#GO:1903046;reproductive process#GO:0022414;gamete generation#GO:0007276;sexual reproduction#GO:0019953;cytokinesis#GO:0000910;nuclear division#GO:0000280;multicellular organismal reproductive process#GO:0048609;cytoskeleton-dependent cytokinesis#GO:0061640;organelle fission#GO:0048285 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000025181.3|UniProtKB=F7FJV1 F7FJV1 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000013414.5|UniProtKB=F7CNJ4 F7CNJ4 SCN11A PTHR10037:SF210 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 11 SUBUNIT ALPHA monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;voltage-gated sodium channel activity#GO:0005248;sodium ion transmembrane transporter activity#GO:0015081 sensory perception#GO:0007600;nervous system process#GO:0050877;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;sensory perception of pain#GO:0019233;action potential#GO:0001508;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;system process#GO:0003008;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;multicellular organismal process#GO:0032501;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220 cation channel complex#GO:0034703;transporter complex#GO:1990351;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;axon#GO:0030424;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000011202.4|UniProtKB=F6SQW8 F6SQW8 SRM PTHR11558:SF11 SPERMIDINE/SPERMINE SYNTHASE SPERMIDINE SYNTHASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596;polyamine metabolic process#GO:0006595;cellular process#GO:0009987;metabolic process#GO:0008152;amine metabolic process#GO:0009308 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 transferase#PC00220 MONDO|Ensembl=ENSMODG00000021031.3|UniProtKB=F6W0L0 F6W0L0 SIK1 PTHR24343:SF204 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE SIK1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000015111.4|UniProtKB=F7F363 F7F363 SAXO5 PTHR34828:SF1 TESTIS-EXPRESSED PROTEIN 45 STABILIZER OF AXONEMAL MICROTUBULES 5 MONDO|Ensembl=ENSMODG00000041541.1|UniProtKB=A0A5F8GA70 A0A5F8GA70 PTHR14652:SF2 TYPE 2 DNA TOPOISOMERASE 6 SUBUNIT B-LIKE TYPE 2 DNA TOPOISOMERASE 6 SUBUNIT B-LIKE organelle fission#GO:0048285;reciprocal meiotic recombination#GO:0007131;sexual reproduction#GO:0019953;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;homologous recombination#GO:0035825;cell cycle process#GO:0022402;reciprocal homologous recombination#GO:0140527;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;primary metabolic process#GO:0044238;meiosis I#GO:0007127;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;meiotic DNA double-strand break formation#GO:0042138;organelle organization#GO:0006996 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000016639.4|UniProtKB=A0A5F8GZC8 A0A5F8GZC8 WSCD1 PTHR45964:SF8 WSCD FAMILY MEMBER CG9164 SIALATE:O-SULFOTRANSFERASE 1 MONDO|Ensembl=ENSMODG00000009161.3|UniProtKB=A0A5F8GCS7 A0A5F8GCS7 PUF60 PTHR47330:SF1 POLY(U)-BINDING-SPLICING FACTOR PUF60-B-RELATED POLY(U)-BINDING-SPLICING FACTOR PUF60 macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA splicing#GO:0043484;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions#GO:0000375;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA metabolic process#GO:1903311;protein-RNA complex organization#GO:0071826;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000007047.3|UniProtKB=F6UFF9 F6UFF9 NR2C2 PTHR24083:SF48 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP C MEMBER 2 signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 CCKR signaling map#P06959>TAK1#P07170 MONDO|Ensembl=ENSMODG00000013745.4|UniProtKB=F6X7M8 F6X7M8 PTHR11783:SF9 SULFOTRANSFERASE SULT SULFOTRANSFERASE 2B1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000013956.2|UniProtKB=F6RSB1 F6RSB1 IL5 PTHR48491:SF1 INTERLEUKIN-5 INTERLEUKIN-5 signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 Interleukin signaling pathway#P00036>Interleukin#P00970;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 MONDO|Ensembl=ENSMODG00000000988.5|UniProtKB=F7DNC9 F7DNC9 HDGFL2 PTHR12550:SF18 HEPATOMA-DERIVED GROWTH FACTOR-RELATED HEPATOMA-DERIVED GROWTH FACTOR-RELATED PROTEIN 2 histone H3K9me2/3 reader activity#GO:0062072;histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;chromatin-protein adaptor activity#GO:0140463 chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000044737.1|UniProtKB=A0A5F8HB24 A0A5F8HB24 MTCP1 PTHR14060:SF8 PROTEIN P13 MTCP-1 PROTEIN P13 MTCP-1 protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 MONDO|Ensembl=ENSMODG00000011715.4|UniProtKB=F7FT59 F7FT59 MAPK1IP1L PTHR35973:SF1 MAPK-INTERACTING AND SPINDLE-STABILIZING PROTEIN-LIKE MAPK-INTERACTING AND SPINDLE-STABILIZING PROTEIN-LIKE MONDO|Ensembl=ENSMODG00000050464.1|UniProtKB=A0A5F8H813 A0A5F8H813 VN2R563 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000037384.1|UniProtKB=A0A5F8GLN3 A0A5F8GLN3 LOC100015725 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015163.5|UniProtKB=F7CF43 F7CF43 HSD17B2 PTHR43313:SF3 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 hormone metabolic process#GO:0042445;lipid biosynthetic process#GO:0008610;steroid metabolic process#GO:0008202;hormone biosynthetic process#GO:0042446;biosynthetic process#GO:0009058;biological regulation#GO:0065007;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;steroid biosynthetic process#GO:0006694;regulation of biological quality#GO:0065008;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 MONDO|Ensembl=ENSMODG00000006739.4|UniProtKB=F7CDB5 F7CDB5 DGAT2 PTHR12317:SF14 DIACYLGLYCEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 neutral lipid metabolic process#GO:0006638;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000003731.5|UniProtKB=F7EVS0 F7EVS0 GTF2A1 PTHR12694:SF7 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription coregulator activity#GO:0003712;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;core promoter sequence-specific DNA binding#GO:0001046;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366 transferase complex#GO:1990234;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 MONDO|Ensembl=ENSMODG00000011699.4|UniProtKB=F7G3R6 F7G3R6 IFT81 PTHR15614:SF2 INTRAFLAGELLAR TRANSPORT PROTEIN 81 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 81 HOMOLOG cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;protein binding#GO:0005515 microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;microtubule-based transport#GO:0099111;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810 intraciliary transport particle B#GO:0030992;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000004457.4|UniProtKB=A0A5F8H046 A0A5F8H046 MEPCE PTHR12315:SF0 BICOID-INTERACTING PROTEIN RELATED 7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;methyltransferase activity#GO:0008168;binding#GO:0005488;nucleic acid binding#GO:0003676;O-methyltransferase activity#GO:0008171;RNA binding#GO:0003723;snRNA binding#GO:0017069 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 MONDO|Ensembl=ENSMODG00000021261.4|UniProtKB=F6T3A4 F6T3A4 CP PTHR11709:SF226 MULTI-COPPER OXIDASE CERULOPLASMIN catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 oxidase#PC00175 MONDO|Ensembl=ENSMODG00000002148.4|UniProtKB=A0A5F8H1Y2 A0A5F8H1Y2 SPPL2A PTHR12174:SF34 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 2A aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;endoplasmic reticulum membrane#GO:0005789;Golgi-associated vesicle#GO:0005798;endomembrane system#GO:0012505;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle subcompartment#GO:0031984;side of membrane#GO:0098552;intracellular organelle#GO:0043229;Golgi-associated vesicle membrane#GO:0030660;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;cytoplasmic side of membrane#GO:0098562;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;vacuole#GO:0005773;cytoplasmic vesicle membrane#GO:0030659;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;lysosomal membrane#GO:0005765 protein modifying enzyme#PC00260;aspartic protease#PC00053 MONDO|Ensembl=ENSMODG00000003642.4|UniProtKB=A0A5F8GV78 A0A5F8GV78 CPNE7 PTHR10857:SF6 COPINE COPINE-7 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 response to stimulus#GO:0050896;response to chemical#GO:0042221;response to calcium ion#GO:0051592;cellular response to chemical stimulus#GO:0070887;response to metal ion#GO:0010038;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000021013.4|UniProtKB=F6QZF9 F6QZF9 PTHR42753:SF9 MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN ML39 ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000004528.4|UniProtKB=F6UQ83 F6UQ83 SLC22A17 PTHR24064:SF216 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 17 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 metal ion transport#GO:0030001;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;transition metal ion transport#GO:0000041;iron ion transport#GO:0006826;iron coordination entity transport#GO:1901678 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000002291.5|UniProtKB=F6ZEF4 F6ZEF4 SH2D3A PTHR14247:SF11 BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN SH2 DOMAIN-CONTAINING PROTEIN 3A MONDO|Ensembl=ENSMODG00000020049.4|UniProtKB=F6ZGE0 F6ZGE0 LOC100617233 PTHR48018:SF109 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8U3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037083.1|UniProtKB=A0A5F8GU28 A0A5F8GU28 monDomV1R1204 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007304.4|UniProtKB=F7EYF8 F7EYF8 PTHR13255:SF1 ATAXIN-10 ATAXIN-10 cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;system development#GO:0048731;cilium organization#GO:0044782;neuron development#GO:0048666;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031 cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;dendritic tree#GO:0097447;dendrite#GO:0030425 MONDO|Ensembl=ENSMODG00000002366.4|UniProtKB=A0A5F8GUZ3 A0A5F8GUZ3 PTHR22574:SF12 FAMILY NOT NAMED GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 5B MONDO|Ensembl=ENSMODG00000025643.2|UniProtKB=F6XW03 F6XW03 PTHR15607:SF14 SYNAPTONEMAL COMPLEX PROTEIN-RELATED SYNAPTONEMAL COMPLEX PROTEIN 2-LIKE condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;synaptonemal structure#GO:0099086;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000015610.3|UniProtKB=F6Z530 F6Z530 FNDC4 PTHR14470:SF2 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 4 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of response to stress#GO:0080134 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000001511.4|UniProtKB=A0A5F8HBI8 A0A5F8HBI8 PLEKHA6 PTHR12752:SF5 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 6 MONDO|Ensembl=ENSMODG00000019472.4|UniProtKB=F6RBC9 F6RBC9 PTHR15036:SF15 PIKACHURIN-LIKE PROTEIN CHONDROITIN SULFATE PROTEOGLYCAN 4B developmental process#GO:0032502;multicellular organism development#GO:0007275;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000005421.3|UniProtKB=F7FVC1 F7FVC1 PSMB10 PTHR11599:SF41 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-10 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;proteasome complex#GO:0000502;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 MONDO|Ensembl=ENSMODG00000039692.1|UniProtKB=A0A5F8GSI3 A0A5F8GSI3 PTHR24103:SF648 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM11 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 response to other organism#GO:0051707;biological regulation#GO:0065007;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to biotic stimulus#GO:0009607;regulation of gene expression#GO:0010468;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000018929.3|UniProtKB=F7GJU9 F7GJU9 NFKBIE PTHR24118:SF37 POTE ANKYRIN DOMAIN NF-KAPPA-B INHIBITOR EPSILON protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 Toll receptor signaling pathway#P00054>IkappaB#P01338;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859 MONDO|Ensembl=ENSMODG00000000693.4|UniProtKB=A0A5F8G910 A0A5F8G910 TMPRSS6 PTHR24253:SF62 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 6 peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000015265.3|UniProtKB=F6VBJ6 F6VBJ6 PTHR32286:SF10 LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G6F LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G6F MONDO|Ensembl=ENSMODG00000012199.4|UniProtKB=F7CEA1 F7CEA1 PTHR47829:SF3 HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12880)-RELATED AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000008627.4|UniProtKB=F6PGT9 F6PGT9 WDR11 PTHR14593:SF5 WD REPEAT-CONTAINING PROTEIN 11 WD REPEAT-CONTAINING PROTEIN 11 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000019402.3|UniProtKB=F6SZG5 F6SZG5 MESD PTHR17600:SF3 MESODERM DEVELOPMENT CANDIDATE 2 LRP CHAPERONE MESD protein binding#GO:0005515;lipoprotein particle receptor binding#GO:0070325;signaling receptor binding#GO:0005102;binding#GO:0005488 MONDO|Ensembl=ENSMODG00000015652.4|UniProtKB=A0A5F8G7L5 A0A5F8G7L5 WDR36 PTHR22840:SF12 WD REPEAT-CONTAINING PROTEIN 36 WD REPEAT-CONTAINING PROTEIN 36 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000002873.4|UniProtKB=F6TSP0 F6TSP0 NMNAT1 PTHR12039:SF21 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE_NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566 nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;pyridine-containing compound metabolic process#GO:0072524;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 nucleotidyltransferase#PC00174;transferase#PC00220 MONDO|Ensembl=ENSMODG00000045785.1|UniProtKB=A0A5F8H0N6 A0A5F8H0N6 PTHR48018:SF170 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5D3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000694.3|UniProtKB=F6WLW5 F6WLW5 PTHR23268:SF92 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 3-1 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000046220.1|UniProtKB=K7DZK2 K7DZK2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000018202.4|UniProtKB=F7B6S6 F7B6S6 PLA1A PTHR11610:SF111 LIPASE PHOSPHOLIPASE A1 MEMBER A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;lipase activity#GO:0016298;glycerophospholipase activity#GO:0004620 lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 2-arachidonoylglycerol biosynthesis#P05726>PLA1#P05735 MONDO|Ensembl=ENSMODG00000001879.2|UniProtKB=A0A5F8GXG1 A0A5F8GXG1 PTHR10836:SF111 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE oxidoreductase activity#GO:0016491;glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 Huntington disease#P00029>GAPDH#P00810;Glycolysis#P00024>Glyceraldehyde 3-phosphate dehydrogenase#P00676 MONDO|Ensembl=ENSMODG00000016696.4|UniProtKB=F7AKT0 F7AKT0 PTHR21650:SF2 MEMBRALIN/KINETOCHORE PROTEIN NUF2 KINETOCHORE PROTEIN NUF2 binding#GO:0005488;protein-containing complex binding#GO:0044877 microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;localization#GO:0051179;kinetochore organization#GO:0051383;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;sexual reproduction#GO:0019953;organelle localization#GO:0051640;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;mitotic metaphase chromosome alignment#GO:0007080;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;meiotic nuclear division#GO:0140013;spindle organization#GO:0007051;mitotic sister chromatid segregation#GO:0000070;nuclear division#GO:0000280;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;sister chromatid segregation#GO:0000819;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;metaphase chromosome alignment#GO:0051310;chromosome localization#GO:0050000;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;attachment of spindle microtubules to kinetochore#GO:0008608;organelle organization#GO:0006996 condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;kinetochore#GO:0000776;supramolecular complex#GO:0099080;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;outer kinetochore#GO:0000940;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000038263.1|UniProtKB=A0A5F8HI99 A0A5F8HI99 EFNB2 PTHR11304:SF18 EPHRIN EPHRIN-B2 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;circulatory system development#GO:0072359;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;vasculature development#GO:0001944;cell projection morphogenesis#GO:0048858;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;regulation of cellular process#GO:0050794;blood vessel development#GO:0001568;ephrin receptor signaling pathway#GO:0048013;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;tube development#GO:0035295;biological regulation#GO:0065007;axon development#GO:0061564;axon guidance#GO:0007411;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502 cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;synaptic membrane#GO:0097060;cell junction#GO:0030054 intercellular signal molecule#PC00207;membrane-bound signaling molecule#PC00152 Angiogenesis#P00005>Eph#P00239 MONDO|Ensembl=ENSMODG00000006213.3|UniProtKB=F7FSC5 F7FSC5 FOXA2 PTHR11829:SF167 FORKHEAD BOX PROTEIN HEPATOCYTE NUCLEAR FACTOR 3-BETA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000007884.4|UniProtKB=F6ZH16 F6ZH16 RBM14 PTHR48039:SF7 RNA-BINDING MOTIF PROTEIN 14B RNA-BINDING PROTEIN 28 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 MONDO|Ensembl=ENSMODG00000041125.1|UniProtKB=K7DZG9 K7DZG9 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000025735.2|UniProtKB=F6T235 F6T235 PTHR17901:SF14 MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1 MAGNESIUM-DEPENDENT PHOSPHATASE 1 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000017583.4|UniProtKB=F7B5A1 F7B5A1 SEC16A PTHR13402:SF13 RGPR-RELATED PROTEIN TRANSPORT PROTEIN SEC16A intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 MONDO|Ensembl=ENSMODG00000015440.4|UniProtKB=A0A5F8HEM5 A0A5F8HEM5 TTC27 PTHR16193:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 27 TETRATRICOPEPTIDE REPEAT PROTEIN 27 MONDO|Ensembl=ENSMODG00000021353.2|UniProtKB=H9H7Z5 H9H7Z5 CTDSP2 PTHR12210:SF187 DULLARD PROTEIN PHOSPHATASE CARBOXY-TERMINAL DOMAIN RNA POLYMERASE II POLYPEPTIDE A SMALL PHOSPHATASE 2 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000044482.1|UniProtKB=A0A5F8H6B2 A0A5F8H6B2 PTHR23226:SF448 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 23 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002599.4|UniProtKB=F7CMJ4 F7CMJ4 TEPSIN PTHR21514:SF0 AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cellular anatomical structure#GO:0110165;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000042954.1|UniProtKB=F6SIU6 F6SIU6 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000043328.1|UniProtKB=A0A5F8GVC6 A0A5F8GVC6 PTHR15601:SF20 STRESS ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN SERP1/RAMP4 STRESS-ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN 2 signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;response to unfolded protein#GO:0006986;cell communication#GO:0007154;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000045500.1|UniProtKB=F7GHL8 F7GHL8 PTHR26452:SF52 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000013437.4|UniProtKB=A0A5F8HFM9 A0A5F8HFM9 WDR48 PTHR19862:SF14 WD REPEAT-CONTAINING PROTEIN 48 WD REPEAT-CONTAINING PROTEIN 48 protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 MONDO|Ensembl=ENSMODG00000001290.3|UniProtKB=A0A5F8GUR2 A0A5F8GUR2 HS3ST1 PTHR10605:SF16 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000049724.1|UniProtKB=A0A5F8GDB2 A0A5F8GDB2 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000025465.2|UniProtKB=F6RJK7 F6RJK7 PTHR23268:SF47 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 11-1 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000005443.3|UniProtKB=F7D0G6 F7D0G6 USF1 PTHR46117:SF1 FI24210P1 UPSTREAM STIMULATORY FACTOR 1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000008383.4|UniProtKB=F7CDR0 F7CDR0 IRF4 PTHR11949:SF6 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 4 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000022859.2|UniProtKB=H9H9Q2 H9H9Q2 LOC100030815 PTHR24237:SF40 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 141B G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000005312.4|UniProtKB=F7DM10 F7DM10 SERPINB12 PTHR11461:SF125 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B12 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000013568.4|UniProtKB=K7DZS5 K7DZS5 PTHR14149:SF12 RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP2 actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;cytoskeletal protein binding#GO:0008092;enzyme activator activity#GO:0008047;calmodulin binding#GO:0005516;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 cytokinesis#GO:0000910;cortical cytoskeleton organization#GO:0030865;cytokinetic process#GO:0032506;actin filament-based process#GO:0030029;mitotic cytokinetic process#GO:1902410;cortical actin cytoskeleton organization#GO:0030866;cytoskeleton-dependent cytokinesis#GO:0061640;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;cell division#GO:0051301;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;actomyosin structure organization#GO:0031032;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;mitotic cell cycle process#GO:1903047;actomyosin contractile ring assembly#GO:0000915;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 cell cortex#GO:0005938;cell periphery#GO:0071944;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000020607.5|UniProtKB=F6ZBI1 F6ZBI1 CYP2U1 PTHR24300:SF364 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 tetrapyrrole binding#GO:0046906;binding#GO:0005488;steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 response to chemical#GO:0042221;response to stimulus#GO:0050896;steroid metabolic process#GO:0008202;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000043632.1|UniProtKB=F6YCY9 F6YCY9 TMEM101 PTHR31034:SF2 TRANSMEMBRANE PROTEIN 101 TRANSMEMBRANE PROTEIN 101 MONDO|Ensembl=ENSMODG00000001840.3|UniProtKB=F6SPH7 F6SPH7 TATDN1 PTHR10060:SF15 TATD FAMILY DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE TATDN1 DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;3'-5'-DNA exonuclease activity#GO:0008296;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 endodeoxyribonuclease#PC00093;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000007115.4|UniProtKB=F6SHV7 F6SHV7 PTHR21354:SF0 ZINC FINGER PROTEIN 511 ZINC FINGER PROTEIN 511 MONDO|Ensembl=ENSMODG00000005538.4|UniProtKB=F7FUP9 F7FUP9 WNT11 PTHR12027:SF7 WNT RELATED PROTEIN WNT-11 binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;system development#GO:0048731;cell fate commitment#GO:0045165;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 MONDO|Ensembl=ENSMODG00000044218.1|UniProtKB=F6RPE1 F6RPE1 LOC100021023 PTHR48018:SF65 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5D14 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017219.4|UniProtKB=F6WYD3 F6WYD3 PTHR15032:SF38 N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;hydrolase activity#GO:0016787 alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;neuronal cell body#GO:0043025;neuron projection#GO:0043005;cell body#GO:0044297 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000038065.1|UniProtKB=A0A5F8G6A2 A0A5F8G6A2 EMP2 PTHR10671:SF32 EPITHELIAL MEMBRANE PROTEIN-RELATED EPITHELIAL MEMBRANE PROTEIN 2 cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031;bleb assembly#GO:0032060;regulation of response to stimulus#GO:0048583;cellular component assembly#GO:0022607;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;regulation of signal transduction#GO:0009966;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;cell projection assembly#GO:0030031;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;localization#GO:0051179;regulation of cell-matrix adhesion#GO:0001952;positive regulation of signaling#GO:0023056;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;cell projection organization#GO:0030030;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000013691.4|UniProtKB=F6QP60 F6QP60 TOP3A PTHR11390:SF21 PROKARYOTIC DNA TOPOISOMERASE DNA TOPOISOMERASE 3-ALPHA isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640 cellular response to stress#GO:0033554;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;DNA helicase complex#GO:0033202;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000015510.2|UniProtKB=F6VZJ2 F6VZJ2 PTHR10489:SF689 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 2 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375 neutrophil chemotaxis#GO:0030593;intracellular signaling cassette#GO:0141124;granulocyte migration#GO:0097530;taxis#GO:0042330;neutrophil migration#GO:1990266;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological quality#GO:0065008;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;leukocyte chemotaxis#GO:0030595;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;leukocyte migration#GO:0050900;biological regulation#GO:0065007;cell migration#GO:0016477;immune response#GO:0006955;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;cell communication#GO:0007154;chemotaxis#GO:0006935;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 cell adhesion molecule#PC00069 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000051217.1|UniProtKB=A0A5F8GVP4 A0A5F8GVP4 monDomV1R1210 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019602.3|UniProtKB=F6Y817 F6Y817 AGBL1 PTHR12756:SF5 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 4 metallopeptidase activity#GO:0008237;binding#GO:0005488;carboxypeptidase activity#GO:0004180;protein binding#GO:0005515;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;metalloexopeptidase activity#GO:0008235;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000021008.4|UniProtKB=F6Z9V8 F6Z9V8 SIM2 PTHR23043:SF19 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA SINGLE-MINDED HOMOLOG 2 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000010094.3|UniProtKB=F6UXK9 F6UXK9 WDR35 PTHR16517:SF1 TUBBY-RELATED WD REPEAT-CONTAINING PROTEIN 35 cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;intraciliary transport#GO:0042073;cellular component organization#GO:0016043;cilium assembly#GO:0060271;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;intraciliary transport particle A#GO:0030991 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000009312.4|UniProtKB=F7GJZ4 F7GJZ4 GAS2 PTHR46756:SF9 TRANSGELIN GROWTH ARREST-SPECIFIC PROTEIN 2 actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000004744.3|UniProtKB=F6XJ86 F6XJ86 PTHR46465:SF4 LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG MAX DIMERIZATION PROTEIN 3 regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;negative regulation of biological process#GO:0048519;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;membrane#GO:0016020;vesicle membrane#GO:0012506 MONDO|Ensembl=ENSMODG00000027318.2|UniProtKB=K7E154 K7E154 PTHR23169:SF21 ENVOPLAKIN EPIPLAKIN binding#GO:0005488 intermediate filament bundle assembly#GO:0045110;cellular component organization or biogenesis#GO:0071840;response to wounding#GO:0009611;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;wound healing#GO:0042060;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;response to stimulus#GO:0050896;intermediate filament cytoskeleton organization#GO:0045104 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;membrane#GO:0016020;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 intermediate filament#PC00129;intermediate filament binding protein#PC00130 MONDO|Ensembl=ENSMODG00000012413.4|UniProtKB=F6PMD7 F6PMD7 SPATS2L PTHR15623:SF8 SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 2-RELATED SPATS2-LIKE PROTEIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000017129.5|UniProtKB=F6WPG6 F6WPG6 ZSCAN20 PTHR23226:SF440 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 20 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010331.4|UniProtKB=F6S9F7 F6S9F7 SPTA1 PTHR11915:SF431 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN ALPHA CHAIN, ERYTHROCYTIC 1 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000004322.4|UniProtKB=F6X6Y2 F6X6Y2 SH3BGRL PTHR12232:SF5 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN ADAPTER SH3BGRL protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-RNA adaptor activity#GO:0140517;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;proteasomal protein catabolic process#GO:0010498;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of biological process#GO:0050789;regulation of translational initiation#GO:0006446;protein catabolic process#GO:0030163;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of cellular process#GO:0048522;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of translation#GO:0045727;positive regulation of biosynthetic process#GO:0009891;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000019406.6|UniProtKB=F6SZE2 F6SZE2 ABHD17C PTHR12277:SF55 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17C palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;catalytic activity#GO:0003824 regulation of biological quality#GO:0065008;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;regulation of synapse structure or activity#GO:0050803;regulation of synapse organization#GO:0050807;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of postsynapse organization#GO:0099175;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000018754.4|UniProtKB=F7EER1 F7EER1 PTHR15367:SF4 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC7-LIKE transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000009506.2|UniProtKB=A0A5F8G1U4 A0A5F8G1U4 PTHR21139:SF2 TRIOSEPHOSPHATE ISOMERASE TRIOSEPHOSPHATE ISOMERASE isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;small molecule biosynthetic process#GO:0044283;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside diphosphate catabolic process#GO:0009134;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;ATP metabolic process#GO:0046034;aldehyde metabolic process#GO:0006081;nicotinamide nucleotide metabolic process#GO:0046496;gluconeogenesis#GO:0006094;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;ribonucleoside diphosphate metabolic process#GO:0009185;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;glyceraldehyde-3-phosphate metabolic process#GO:0019682;oxoacid metabolic process#GO:0043436;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;ADP metabolic process#GO:0046031;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate biosynthetic process#GO:0016051;ADP catabolic process#GO:0046032;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052 metabolite interconversion enzyme#PC00262;isomerase#PC00135 Glycolysis#P00024>Triosephosphate isomerase#P00673 MONDO|Ensembl=ENSMODG00000040537.1|UniProtKB=A0A5F8GR54 A0A5F8GR54 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000013599.4|UniProtKB=A0A5F8H0E1 A0A5F8H0E1 CCDC13 PTHR31935:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 13 COILED-COIL DOMAIN-CONTAINING PROTEIN 13 plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;cytoplasmic microtubule organization#GO:0031122;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;non-motile cilium assembly#GO:1905515;organelle assembly#GO:0070925 MONDO|Ensembl=ENSMODG00000019733.4|UniProtKB=F6X3Z0 F6X3Z0 AP3B1 PTHR11134:SF10 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-3 COMPLEX SUBUNIT BETA-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 microtubule-based transport#GO:0099111;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;cellular component organization#GO:0016043;establishment of organelle localization#GO:0051656;melanosome organization#GO:0032438;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;microtubule-based process#GO:0007017;organelle organization#GO:0006996;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;lysosome organization#GO:0007040;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;cellular pigmentation#GO:0033059;axonal transport#GO:0098930;organelle localization#GO:0051640;pigmentation#GO:0043473;localization#GO:0051179;Golgi to vacuole transport#GO:0006896;vacuole organization#GO:0007033;anterograde axonal transport#GO:0008089;microtubule-based movement#GO:0007018;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;vacuolar transport#GO:0007034;lytic vacuole organization#GO:0080171;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vesicle cytoskeletal trafficking#GO:0099518;anterograde synaptic vesicle transport#GO:0048490;axo-dendritic transport#GO:0008088;vesicle localization#GO:0051648;cytoskeleton-dependent intracellular transport#GO:0030705 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000001387.4|UniProtKB=A0A5F8GXD7 A0A5F8GXD7 EIF5B PTHR43381:SF4 TRANSLATION INITIATION FACTOR IF-2-RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 5B translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000008058.4|UniProtKB=A0A5F8H0L9 A0A5F8H0L9 SPMIP6 PTHR35664:SF1 SPERMATID-SPECIFIC MANCHETTE-RELATED PROTEIN 1 SPERM MICROTUBULE INNER PROTEIN 6 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;perinuclear region of cytoplasm#GO:0048471;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000047515.1|UniProtKB=H9H8F1 H9H8F1 LOC100618260 PTHR48002:SF109 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K15 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000922.4|UniProtKB=F6ZGK3 F6ZGK3 DEUP1 PTHR18875:SF5 SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO DEUTEROSOME ASSEMBLY PROTEIN 1 centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell differentiation#GO:0030154;centriole replication#GO:0007099;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;epithelium development#GO:0060429;cellular component assembly#GO:0022607;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;developmental process#GO:0032502;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869 intracellular organelle#GO:0043229;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000020496.4|UniProtKB=F7F529 F7F529 RASSF9 PTHR15286:SF10 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 9 vesicle membrane#GO:0012506;cytosol#GO:0005829;membrane#GO:0016020;cytoplasm#GO:0005737;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi-associated vesicle#GO:0005798;recycling endosome#GO:0055037;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;vesicle#GO:0031982;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;trans-Golgi network transport vesicle#GO:0030140;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006452.5|UniProtKB=F7FH14 F7FH14 CSRNP3 PTHR13580:SF13 TGF-BETA INDUCED APOPTOSIS PROTEIN CYSTEINE_SERINE-RICH NUCLEAR PROTEIN 3 sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000010534.3|UniProtKB=F6ZF04 F6ZF04 PTHR46174:SF1 CXXC-TYPE ZINC FINGER PROTEIN 1 CXXC-TYPE ZINC FINGER PROTEIN 1 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000020107.3|UniProtKB=F7EAI4 F7EAI4 CLP1 PTHR12755:SF6 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000006078.4|UniProtKB=F7FEG2 F7FEG2 ODF2 PTHR23162:SF8 OUTER DENSE FIBER OF SPERM TAILS 2 OUTER DENSE FIBER PROTEIN 2 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of organelle assembly#GO:1902115;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of cilium assembly#GO:1902017;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection assembly#GO:0060491 intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000005080.4|UniProtKB=F7A4N4 F7A4N4 PTHR24383:SF20 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 44 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000000720.5|UniProtKB=F6W6G7 F6W6G7 CHD6 PTHR45623:SF8 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD6 ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;DNA binding#GO:0003677;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;ribonucleoside triphosphate phosphatase activity#GO:0017111;histone binding#GO:0042393;catalytic activity, acting on a nucleic acid#GO:0140640;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 chromatin organization#GO:0006325;biological regulation#GO:0065007;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000009678.4|UniProtKB=F6YBW3 F6YBW3 EIF3M PTHR15350:SF2 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT M translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 eukaryotic translation initiation factor 3 complex#GO:0005852;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000024910.3|UniProtKB=F6WBL8 F6WBL8 ELMOD2 PTHR12771:SF47 ENGULFMENT AND CELL MOTILITY ELMO DOMAIN-CONTAINING PROTEIN 2 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cilium organization#GO:0044782;organelle assembly#GO:0070925;regulation of defense response#GO:0031347;cell projection organization#GO:0030030;regulation of response to biotic stimulus#GO:0002831;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of response to stress#GO:0080134;plasma membrane bounded cell projection assembly#GO:0120031;regulation of response to stimulus#GO:0048583;regulation of response to external stimulus#GO:0032101;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010547.3|UniProtKB=F6YRY9 F6YRY9 HIVEP1 PTHR45944:SF3 SCHNURRI, ISOFORM F ZINC FINGER PROTEIN 40 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000005145.4|UniProtKB=F7EQ64 F7EQ64 TTF2 PTHR45626:SF50 TRANSCRIPTION TERMINATION FACTOR 2-RELATED TRANSCRIPTION TERMINATION FACTOR 2 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094 macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 MONDO|Ensembl=ENSMODG00000019203.4|UniProtKB=F6ZIV3 F6ZIV3 CRLF3 PTHR23389:SF12 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 CYTOKINE RECEPTOR-LIKE FACTOR 3 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000025689.3|UniProtKB=F6TJQ0 F6TJQ0 SFT2D1 PTHR23137:SF24 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN SFT2A MONDO|Ensembl=ENSMODG00000002310.3|UniProtKB=H9H605 H9H605 MRPL32 PTHR21026:SF2 39S RIBOSOMAL PROTEIN L32, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL32M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000007562.4|UniProtKB=F7FZZ2 F7FZZ2 PTHR13464:SF0 TRANSCRIPTIONAL REGULATOR PROTEIN HCNGP SAP30-BINDING PROTEIN nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000015789.4|UniProtKB=F6Z426 F6Z426 CRELD2 PTHR24034:SF110 EGF-LIKE DOMAIN-CONTAINING PROTEIN PROTEIN DISULFIDE ISOMERASE CRELD2 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000018625.4|UniProtKB=F7B305 F7B305 PXYLP1 PTHR11567:SF213 ACID PHOSPHATASE-RELATED 2-PHOSPHOXYLOSE PHOSPHATASE 1 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000018373.4|UniProtKB=F6QVX5 F6QVX5 WASHC1 PTHR23331:SF5 CXYORF1 WAS PROTEIN FAMILY HOMOLOG 2-RELATED cellular component organization#GO:0016043;export from cell#GO:0140352;cytosolic transport#GO:0016482;endocytic recycling#GO:0032456;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;localization within membrane#GO:0051668;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;secretion by cell#GO:0032940;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;exocytosis#GO:0006887;endosomal transport#GO:0016197;actin filament organization#GO:0007015;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;endosome#GO:0005768;recycling endosome#GO:0055037;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000019343.3|UniProtKB=H9H7B4 H9H7B4 LOC100618178 PTHR48002:SF112 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4Q3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012138.3|UniProtKB=A0A5F8HF22 A0A5F8HF22 FIBCD1 PTHR19143:SF45 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C DOMAIN-CONTAINING PROTEIN 1 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000016684.6|UniProtKB=F7DMG1 F7DMG1 TAF4 PTHR15138:SF18 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Huntington disease#P00029>TAFII130#P00806;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 MONDO|Ensembl=ENSMODG00000004898.4|UniProtKB=K7E1D6 K7E1D6 DPP6 PTHR11731:SF20 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED A-TYPE POTASSIUM CHANNEL MODULATORY PROTEIN DPP6 molecular function regulator activity#GO:0098772;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;ion channel regulator activity#GO:0099106;catalytic activity#GO:0003824;channel regulator activity#GO:0016247;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108 biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;regulation of localization#GO:0032879;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;proteolysis#GO:0006508 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000014578.4|UniProtKB=F7ASM8 F7ASM8 CMPK2 PTHR10344:SF5 THYMIDYLATE KINASE UMP-CMP KINASE 2, MITOCHONDRIAL kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleoside diphosphate metabolic process#GO:0009132 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 nucleotide kinase#PC00172;kinase#PC00137;transferase#PC00220 MONDO|Ensembl=ENSMODG00000046045.1|UniProtKB=A0A5F8GFH3 A0A5F8GFH3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000039655.1|UniProtKB=A0A5F8G5F9 A0A5F8G5F9 PTHR40389:SF3 ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED IGE-BINDING PROTEIN MONDO|Ensembl=ENSMODG00000043542.1|UniProtKB=A0A5F8G9I9 A0A5F8G9I9 PTHR13596:SF2 SMALL EDRK-RICH FACTOR 1 SMALL EDRK-RICH FACTOR 2 MONDO|Ensembl=ENSMODG00000001355.3|UniProtKB=A0A5F8GEA7 A0A5F8GEA7 BPIFC PTHR10504:SF17 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED BPI FOLD-CONTAINING FAMILY C PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000014471.4|UniProtKB=F7A5E1 F7A5E1 ALG9 PTHR22760:SF2 GLYCOSYLTRANSFERASE ALPHA-1,2-MANNOSYLTRANSFERASE ALG9 glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000011968.4|UniProtKB=F7CUT8 F7CUT8 MAPKAPK3 PTHR24349:SF64 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-ACTIVATED PROTEIN KINASE 3 catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;kinase binding#GO:0019900;protein serine/threonine kinase activity#GO:0004674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;calcium/calmodulin-dependent protein kinase activity#GO:0004683;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;transferase activity#GO:0016740;calmodulin binding#GO:0005516;kinase activity#GO:0016301;mitogen-activated protein kinase binding#GO:0051019 response to peptide#GO:1901652;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;toll-like receptor signaling pathway#GO:0002224;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;regulation of response to external stimulus#GO:0032101;response to chemical#GO:0042221;response to cytokine#GO:0034097;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Angiogenesis#P00005>MAPKAPK2/3#P00244;p38 MAPK pathway#P05918>MAPKAP-K3#P05919;VEGF signaling pathway#P00056>MAPKAPK2/3#P01415;Ras Pathway#P04393>MAPKAP#P04564 MONDO|Ensembl=ENSMODG00000028384.2|UniProtKB=K7E3U4 K7E3U4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000025739.3|UniProtKB=F6T1Z5 F6T1Z5 C14orf39 PTHR35449:SF1 PROTEIN SIX6OS1 PROTEIN SIX6OS1 homologous chromosome pairing at meiosis#GO:0007129;oogenesis#GO:0048477;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;chromosome segregation#GO:0007059;DNA recombination#GO:0006310;chromosome organization involved in meiotic cell cycle#GO:0070192;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cell differentiation#GO:0030154;response to stimulus#GO:0050896;gamete generation#GO:0007276;cell cycle process#GO:0022402;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;meiosis I#GO:0007127;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;male gamete generation#GO:0048232;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;DNA double-strand break processing#GO:0000729;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;DNA damage response#GO:0006974;DNA repair#GO:0006281;reproductive process#GO:0022414;homologous recombination#GO:0035825;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;germ cell development#GO:0007281;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982 organelle lumen#GO:0043233;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;central element#GO:0000801;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;synaptonemal structure#GO:0099086;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794 MONDO|Ensembl=ENSMODG00000017197.4|UniProtKB=A0A5F8GPC6 A0A5F8GPC6 AP1S2 PTHR11753:SF19 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-1 COMPLEX SUBUNIT SIGMA-2 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000014680.4|UniProtKB=F7E7J3 F7E7J3 SMO PTHR11309:SF35 FRIZZLED PROTEIN SMOOTHENED transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor activity#GO:0038023;protein binding#GO:0005515;molecular transducer activity#GO:0060089;Wnt-protein binding#GO:0017147 developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon development#GO:0061564;axon guidance#GO:0007411;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;pattern specification process#GO:0007389;smoothened signaling pathway#GO:0007224;system development#GO:0048731;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;central nervous system development#GO:0007417;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902 somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;dendritic tree#GO:0097447;cilium#GO:0005929;dendrite#GO:0030425 transmembrane signal receptor#PC00197 Hedgehog signaling pathway#P00025>Smoothened#P00685 MONDO|Ensembl=ENSMODG00000037969.1|UniProtKB=A0A5F8HIH9 A0A5F8HIH9 PDE12 PTHR12121:SF37 CARBON CATABOLITE REPRESSOR PROTEIN 4 2',5'-PHOSPHODIESTERASE 12 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000011535.4|UniProtKB=F6QXE7 F6QXE7 PMS1 PTHR10073:SF54 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL PMS1 PROTEIN HOMOLOG 1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;endonuclease activity#GO:0004519 macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mismatch repair#GO:0006298;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000019456.2|UniProtKB=F6RWR2 F6RWR2 FES PTHR24418:SF197 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FES_FPS catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;signaling receptor binding#GO:0005102;non-membrane spanning protein tyrosine kinase activity#GO:0004715 developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;response to external stimulus#GO:0009605;cellular developmental process#GO:0048869;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;response to chemical#GO:0042221;taxis#GO:0042330;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell adhesion#GO:0007155;chemotaxis#GO:0006935;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;locomotion#GO:0040011;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 Axon guidance mediated by semaphorins#P00007>Fes#P00332 MONDO|Ensembl=ENSMODG00000039529.1|UniProtKB=A0A5F8G2U5 A0A5F8G2U5 PTHR46091:SF1 BLR7054 PROTEIN ALL-TRANS-RETINOL 13,14-REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 terpenoid metabolic process#GO:0006721;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;cellular process#GO:0009987;biological regulation#GO:0065007;hormone metabolic process#GO:0042445 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000016824.4|UniProtKB=F7B3H4 F7B3H4 NUDT5 PTHR11839:SF1 UDP/ADP-SUGAR PYROPHOSPHATASE ADP-SUGAR PYROPHOSPHATASE hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787 cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 metabolite interconversion enzyme#PC00262;pyrophosphatase#PC00196 MONDO|Ensembl=ENSMODG00000044101.1|UniProtKB=F7A2G3 F7A2G3 LOC100028283 PTHR26452:SF55 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000009507.3|UniProtKB=A0A5F8H2S4 A0A5F8H2S4 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000019544.5|UniProtKB=F7B2B5 F7B2B5 PLIN1 PTHR47138:SF1 PERILIPIN-1 PERILIPIN-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 catabolic process#GO:0009056;lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811 MONDO|Ensembl=ENSMODG00000011055.3|UniProtKB=F7EML9 F7EML9 STARD6 PTHR46374:SF2 PROTEIN CBG07384 STAR-RELATED LIPID TRANSFER PROTEIN 6 MONDO|Ensembl=ENSMODG00000019504.4|UniProtKB=F6VU14 F6VU14 C1H20orf96 PTHR28574:SF1 RIKEN CDNA 6820408C15 RIKEN CDNA 6820408C15 GENE MONDO|Ensembl=ENSMODG00000051305.1|UniProtKB=A0A5F8G8B6 A0A5F8G8B6 PTHR24020:SF90 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXI) CHAIN extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000006533.4|UniProtKB=F7CDN2 F7CDN2 DESI2 PTHR12378:SF6 DESUMOYLATING ISOPEPTIDASE DEUBIQUITINASE DESI2 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;deubiquitinase activity#GO:0101005 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000020044.2|UniProtKB=F6ZH50 F6ZH50 LOC100023762 PTHR48018:SF35 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006596.4|UniProtKB=F7AK33 F7AK33 MGRN1 PTHR22996:SF2 MAHOGUNIN E3 UBIQUITIN-PROTEIN LIGASE MGRN1 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 cell communication#GO:0007154;localization#GO:0051179;cellular localization#GO:0051641;smoothened signaling pathway#GO:0007224;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;establishment of localization#GO:0051234;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;signal transduction#GO:0007165;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000029109.2|UniProtKB=A0A5F8GK04 A0A5F8GK04 PTHR31594:SF14 AIG1-TYPE G DOMAIN-CONTAINING PROTEIN FIBRONECTIN TYPE III AND SPRY DOMAIN CONTAINING 1 LIKE MONDO|Ensembl=ENSMODG00000045802.1|UniProtKB=A0A5F8HBC6 A0A5F8HBC6 LOC100617486 PTHR24381:SF27 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 180 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000037530.1|UniProtKB=A0A5F8H3N1 A0A5F8H3N1 LOC107649133 PTHR13172:SF5 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597 mitochondrial intermembrane space#GO:0005758;membrane-enclosed lumen#GO:0031974;mitochondrial envelope#GO:0005740;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000010363.4|UniProtKB=A0A5F8G447 A0A5F8G447 MAK PTHR24055:SF194 MITOGEN-ACTIVATED PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE MAK protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;organelle assembly#GO:0070925;localization#GO:0051179;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;intraciliary transport#GO:0042073;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;signal transduction#GO:0007165;cellular component assembly#GO:0022607;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell projection organization#GO:0030030;response to stimulus#GO:0050896;signaling#GO:0023052 nucleus#GO:0005634;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000051201.1|UniProtKB=F6WG96 F6WG96 PTHR13011:SF0 TFIIF-ALPHA GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1 RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;transcription factor binding#GO:0008134;binding#GO:0005488 DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription regulation#P00023>TFIIFalpha#P00663;Transcription regulation by bZIP transcription factor#P00055>TFIIFalpha#P01391 MONDO|Ensembl=ENSMODG00000001269.4|UniProtKB=F7CIY3 F7CIY3 PTHR24024:SF15 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A PULMONARY SURFACTANT-ASSOCIATED PROTEIN D molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;positive regulation of endocytosis#GO:0045807;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955;complement activation#GO:0006956;positive regulation of cellular process#GO:0048522;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;regulation of transport#GO:0051049;regulation of localization#GO:0032879;humoral immune response#GO:0006959;immune effector process#GO:0002252;regulation of endocytosis#GO:0030100;defense response to other organism#GO:0098542;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;activation of immune response#GO:0002253;positive regulation of transport#GO:0051050;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;immune system process#GO:0002376;positive regulation of cellular component organization#GO:0051130;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211;surfactant#PC00212 MONDO|Ensembl=ENSMODG00000012366.4|UniProtKB=F7G1X3 F7G1X3 CNDP1 PTHR43270:SF1 BETA-ALA-HIS DIPEPTIDASE BETA-ALA-HIS DIPEPTIDASE catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000014011.3|UniProtKB=F7GKY6 F7GKY6 ADGRG1 PTHR12011:SF318 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G1 molecular transducer activity#GO:0060089;binding#GO:0005488;glycosaminoglycan binding#GO:0005539;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;carbohydrate derivative binding#GO:0097367;heparin binding#GO:0008201 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000014826.4|UniProtKB=F7D1Q7 F7D1Q7 ANKFN1 PTHR21437:SF3 WIDE AWAKE ANKYRIN REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 1 mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of establishment or maintenance of cell polarity#GO:0032878;establishment of spindle localization#GO:0051293;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;localization#GO:0051179;spindle localization#GO:0051653;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;establishment or maintenance of cell polarity#GO:0007163;organelle localization#GO:0051640;mitotic cell cycle#GO:0000278;establishment of organelle localization#GO:0051656;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000003735.4|UniProtKB=F7EW19 F7EW19 GPCPD1 PTHR22958:SF43 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1 phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 glycerophospholipid catabolic process#GO:0046475;organophosphate catabolic process#GO:0046434;lipid metabolic process#GO:0006629;glycerolipid catabolic process#GO:0046503;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;cellular process#GO:0009987;lipid catabolic process#GO:0016042;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000005742.3|UniProtKB=F6QEA6 F6QEA6 PTHR19367:SF51 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 16 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000047165.1|UniProtKB=A0A5F8H2Z5 A0A5F8H2Z5 PTHR23227:SF86 BUCENTAUR RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000027423.2|UniProtKB=K7E2B1 K7E2B1 STUM PTHR21676:SF1 PROTEIN STUM PROTEIN STUM HOMOLOG MONDO|Ensembl=ENSMODG00000005943.3|UniProtKB=A0A5F8G614 A0A5F8G614 ZDHHC1 PTHR22883:SF8 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC1 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 localization within membrane#GO:0051668;immune system process#GO:0002376;response to virus#GO:0009615;cellular localization#GO:0051641;localization#GO:0051179;antiviral innate immune response#GO:0140374;defense response to virus#GO:0051607;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;protein targeting#GO:0006605;response to stimulus#GO:0050896;protein targeting to membrane#GO:0006612;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of protein localization#GO:0045184;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;establishment of protein localization to membrane#GO:0090150;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000010927.4|UniProtKB=F7F4Y9 F7F4Y9 TRNAU1AP PTHR37457:SF2 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1 tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of macromolecule metabolic process#GO:0060255;protein biosynthetic process#GO:0160307;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;translation#GO:0006412;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;translational elongation#GO:0006414;post-transcriptional regulation of gene expression#GO:0010608 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000044649.1|UniProtKB=A0A5F8GTC7 A0A5F8GTC7 PTHR21454:SF31 DPH3 HOMOLOG-RELATED DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3 cation binding#GO:0043169;iron ion binding#GO:0005506;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein modification process#GO:0036211 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000015768.3|UniProtKB=F6ZSZ1 F6ZSZ1 ZG16 PTHR33589:SF4 OS11G0524900 PROTEIN ZYMOGEN GRANULE MEMBRANE PROTEIN 16 MONDO|Ensembl=ENSMODG00000020275.4|UniProtKB=F7C0X4 F7C0X4 NNT PTHR10160:SF22 NAD(P) TRANSHYDROGENASE NAD(P) TRANSHYDROGENASE, MITOCHONDRIAL nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488;purine nucleotide binding#GO:0017076;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000021357.4|UniProtKB=H9H7Z8 H9H7Z8 YIPF1 PTHR12822:SF4 PROTEIN YIPF PROTEIN YIPF1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000043556.1|UniProtKB=A0A5F8GFQ5 A0A5F8GFQ5 monDomV1R1264 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000043724.1|UniProtKB=A0A5F8H1G4 A0A5F8H1G4 PTHR23267:SF486 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 14_DELTA VARIABLE 4 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000007739.4|UniProtKB=F7C403 F7C403 PTHR19878:SF7 AUTOPHAGY PROTEIN 16-LIKE PROTEIN ATG16L2 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macroautophagy#GO:0016236;catabolic process#GO:0009056;cellular component assembly#GO:0022607;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;autophagosome#GO:0005776;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000019367.4|UniProtKB=F6WTD3 F6WTD3 SLC28A1 PTHR10590:SF16 SODIUM/NUCLEOSIDE COTRANSPORTER SODIUM_NUCLEOSIDE COTRANSPORTER 1 solute:sodium symporter activity#GO:0015370;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:monoatomic cation symporter activity#GO:0015294;nucleoside transmembrane transporter activity#GO:0005337;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000004615.3|UniProtKB=F6Y3C1 F6Y3C1 OGT PTHR44366:SF1 UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000048497.1|UniProtKB=A0A5F8H4G7 A0A5F8H4G7 KCTD6 PTHR14499:SF10 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING POTASSIUM CHANNEL TETRAMERIZATION DOMAIN CONTAINING 6 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014273.4|UniProtKB=F6X1I7 F6X1I7 INTS2 PTHR28608:SF1 INTEGRATOR COMPLEX SUBUNIT 2 INTEGRATOR COMPLEX SUBUNIT 2 DNA-templated transcription#GO:0006351;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;catabolic process#GO:0009056;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound catabolic process#GO:0034655;snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular organelle#GO:0043229;integrator complex#GO:0032039;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000013249.4|UniProtKB=A0A5F8GNB3 A0A5F8GNB3 NLRX1 PTHR24106:SF152 NACHT, LRR AND CARD DOMAINS-CONTAINING NLR FAMILY MEMBER X1 molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;regulation of defense response#GO:0031347;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000016377.4|UniProtKB=F6Q6Q3 F6Q6Q3 TFAP4 PTHR15741:SF27 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR AP-4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000039829.1|UniProtKB=A0A5F8HKE6 A0A5F8HKE6 monDomV1R1215 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012618.4|UniProtKB=F6S2L8 F6S2L8 TEX10 PTHR16056:SF39 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN TESTIS-EXPRESSED PROTEIN 10 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000003496.4|UniProtKB=F7CS02 F7CS02 SPATA2L PTHR15326:SF7 SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC SPERMATOGENESIS-ASSOCIATED PROTEIN 2-LIKE PROTEIN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000008449.4|UniProtKB=A0A5F8H2V3 A0A5F8H2V3 TRRAP PTHR11139:SF1 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to stress#GO:0033554;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;DNA damage response#GO:0006974 nucleus#GO:0005634;chromatin#GO:0000785;SAGA complex#GO:0000124;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000009424.4|UniProtKB=F7BLF1 F7BLF1 SLC18A2 PTHR23506:SF30 GH10249P SYNAPTIC VESICULAR AMINE TRANSPORTER solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;chloride transmembrane transporter activity#GO:0015108;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;solute:sodium symporter activity#GO:0015370;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 localization#GO:0051179;vesicle-mediated transport in synapse#GO:0099003;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 axon terminus#GO:0043679;organelle membrane#GO:0031090;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;axon#GO:0030424;neuron projection terminus#GO:0044306;intracellular membrane-bounded organelle#GO:0043231;terminal bouton#GO:0043195;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;neuron projection#GO:0043005;presynapse#GO:0098793;secretory vesicle#GO:0099503;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular vesicle#GO:0097708 secondary carrier transporter#PC00258;transporter#PC00227 5HT4 type receptor mediated signaling pathway#P04376>5HT vesicular transporter#P04432;5HT1 type receptor mediated signaling pathway#P04373>5HT vesicular transporter#P04410;CCKR signaling map#P06959>VMAT2#G07295;Dopamine receptor mediated signaling pathway#P05912>VAT2#P05960;Nicotine pharmacodynamics pathway#P06587>SLC18A2#P06604;5HT2 type receptor mediated signaling pathway#P04374>5HT vesicular transporter#P04418;5HT3 type receptor mediated signaling pathway#P04375>5HT vesicular transporter#P04424;CCKR signaling map#P06959>VMAT2#P07137;CCKR signaling map#P06959>VMAT2#G07002;Adrenaline and noradrenaline biosynthesis#P00001>VAT2#P00070;Adrenaline and noradrenaline biosynthesis#P00001>VAT1#P00071 MONDO|Ensembl=ENSMODG00000005308.4|UniProtKB=F7DM73 F7DM73 ARSJ PTHR10342:SF69 ARYLSULFATASE ARYLSULFATASE J catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 MONDO|Ensembl=ENSMODG00000001264.4|UniProtKB=F7CJ04 F7CJ04 LARGE1 PTHR12270:SF48 GLYCOSYLTRANSFERASE-RELATED XYLOSYL- AND GLUCURONYLTRANSFERASE LARGE1 pentosyltransferase activity#GO:0016763;glucuronosyltransferase activity#GO:0015020;xylosyltransferase activity#GO:0042285;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein O-linked glycosylation via mannose#GO:0035269;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000001540.4|UniProtKB=F7EMG8 F7EMG8 PTHR11852:SF4 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE LITTLE ELONGATION COMPLEX SUBUNIT 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase III#GO:0042796;RNA metabolic process#GO:0016070;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;snRNA transcription#GO:0009301;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000001085.4|UniProtKB=A0A5F8GK14 A0A5F8GK14 MFAP4 PTHR19143:SF225 FIBRINOGEN/TENASCIN/ANGIOPOEITIN MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 4 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;extracellular matrix assembly#GO:0085029;cellular component assembly#GO:0022607;extracellular structure organization#GO:0043062;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000003313.2|UniProtKB=F7DYL6 F7DYL6 LOC100015999 PTHR48018:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 974 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019499.4|UniProtKB=F6VUV1 F6VUV1 PLPP1 PTHR10165:SF26 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;lipid modification#GO:0030258 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000008370.3|UniProtKB=F7CDX7 F7CDX7 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019338.4|UniProtKB=A0A5F8GZ73 A0A5F8GZ73 TMEM145 PTHR23252:SF24 INTIMAL THICKNESS RECEPTOR-RELATED TRANSMEMBRANE PROTEIN 145 MONDO|Ensembl=ENSMODG00000003795.4|UniProtKB=F6ZKK3 F6ZKK3 LOC100020352 PTHR19282:SF120 TETRASPANIN TETRASPANIN-36 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000762.4|UniProtKB=F6SSZ9 F6SSZ9 DUSP13B PTHR45682:SF10 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE 13B hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000019032.4|UniProtKB=F7BLI0 F7BLI0 PRPH2 PTHR19282:SF202 TETRASPANIN PERIPHERIN-2 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019855.4|UniProtKB=H9H7I9 H9H7I9 PTGES3 PTHR22932:SF3 TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE PROSTAGLANDIN E SYNTHASE 3 protein binding#GO:0005515;Hsp90 protein binding#GO:0051879;binding#GO:0005488;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;heat shock protein binding#GO:0031072;catalytic activity#GO:0003824;protein-folding chaperone binding#GO:0051087 cellular component organization#GO:0016043;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;protein-containing complex assembly#GO:0065003;small molecule metabolic process#GO:0044281;ribonucleoprotein complex biogenesis#GO:0022613;protein folding#GO:0006457;oxoacid metabolic process#GO:0043436;nucleic acid biosynthetic process#GO:0141187;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;telomere maintenance via telomerase#GO:0007004;telomere maintenance via telomere lengthening#GO:0010833;gene expression#GO:0010467;icosanoid metabolic process#GO:0006690;protein maturation#GO:0051604;cellular component assembly#GO:0022607;icosanoid biosynthetic process#GO:0046456;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;unsaturated fatty acid metabolic process#GO:0033559;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;carboxylic acid biosynthetic process#GO:0046394;chaperone-mediated protein complex assembly#GO:0051131;prostaglandin metabolic process#GO:0006693;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;telomere organization#GO:0032200;macromolecule biosynthetic process#GO:0009059;lipid biosynthetic process#GO:0008610;unsaturated fatty acid biosynthetic process#GO:0006636;nucleobase-containing compound metabolic process#GO:0006139;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;fatty acid metabolic process#GO:0006631;RNA-templated DNA biosynthetic process#GO:0006278;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;telomere maintenance#GO:0000723 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000024097.2|UniProtKB=F6Y2D6 F6Y2D6 PTHR10540:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED COP9 SIGNALOSOME COMPLEX SUBUNIT 6 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000047376.1|UniProtKB=K7E341 K7E341 PTHR26450:SF52 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR FAMILY 56 SUBFAMILY A MEMBER 41, PSEUDOGENE 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016593.2|UniProtKB=F6ZDB9 F6ZDB9 PRSS27 PTHR24253:SF144 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27 catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000037654.1|UniProtKB=F7FBN9 F7FBN9 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000017202.4|UniProtKB=F6XEZ3 F6XEZ3 ZRSR2 PTHR12620:SF4 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT ZINC FINGER (CCCH TYPE), RNA-BINDING MOTIF AND SERINE_ARGININE RICH 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;pre-mRNA binding#GO:0036002 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000010044.4|UniProtKB=A0A5F8GZN9 A0A5F8GZN9 SLC35B3 PTHR10778:SF8 SOLUTE CARRIER FAMILY 35 MEMBER B ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 2 nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;purine nucleotide transmembrane transporter activity#GO:0015216;carbohydrate derivative transmembrane transporter activity#GO:1901505;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nitrogen compound transport#GO:0071705 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000019012.3|UniProtKB=F7C5Y6 F7C5Y6 PTHR14054:SF14 REPETIN REPETIN cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000004743.4|UniProtKB=F7AEJ7 F7AEJ7 LOC130457150 PTHR23158:SF54 MELANOMA INHIBITORY ACTIVITY-RELATED TRANSPORT AND GOLGI ORGANIZATION PROTEIN 1 HOMOLOG localization#GO:0051179;protein secretion#GO:0009306;secretion#GO:0046903;cellular localization#GO:0051641;secretion by cell#GO:0032940;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;export from cell#GO:0140352;protein localization to extracellular region#GO:0071692;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000003554.3|UniProtKB=A0A5F8GAQ1 A0A5F8GAQ1 ETAA1 PTHR16434:SF2 EWING'S TUMOR-ASSOCIATED ANTIGEN 1 ETAA1 EWING'S TUMOR-ASSOCIATED ANTIGEN 1 protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;regulation of response to stress#GO:0080134;nucleobase-containing compound metabolic process#GO:0006139;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;replication fork processing#GO:0031297;cellular process#GO:0009987;response to stress#GO:0006950;regulation of cellular response to stress#GO:0080135;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000024477.2|UniProtKB=F7GFG7 F7GFG7 PTHR23087:SF12 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-14 chromatin binding#GO:0003682;binding#GO:0005488 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000024183.2|UniProtKB=F6T4H5 F6T4H5 PTHR14350:SF2 ARGININE VASOPRESSIN-INDUCED PROTEIN 1 ARGININE VASOPRESSIN-INDUCED PROTEIN 1 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 MONDO|Ensembl=ENSMODG00000010517.3|UniProtKB=F7DR85 F7DR85 IDO1 PTHR28657:SF2 INDOLEAMINE 2,3-DIOXYGENASE INDOLEAMINE 2,3-DIOXYGENASE 1 oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;pyridine-containing compound metabolic process#GO:0072524;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;indole-containing compound metabolic process#GO:0042430;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000016983.4|UniProtKB=F6Q9V8 F6Q9V8 SEMA3A PTHR11036:SF23 SEMAPHORIN SEMAPHORIN-3A signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102 locomotion#GO:0040011;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;axon development#GO:0061564;stem cell differentiation#GO:0048863;tissue development#GO:0009888;neural crest cell development#GO:0014032;cell migration#GO:0016477;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;positive regulation of cell motility#GO:2000147;cell differentiation#GO:0030154;cell projection organization#GO:0030030;signaling#GO:0023052;generation of neurons#GO:0048699;response to chemical#GO:0042221;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;mesenchymal cell differentiation#GO:0048762;neural crest cell differentiation#GO:0014033;animal organ development#GO:0048513;cell projection morphogenesis#GO:0048858;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;regulation of cellular process#GO:0050794;stem cell development#GO:0048864;chemotaxis#GO:0006935;anatomical structure development#GO:0048856;axon guidance#GO:0007411;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;mesenchyme development#GO:0060485;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;neuron projection development#GO:0031175;neural crest cell migration#GO:0001755;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;taxis#GO:0042330;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;axon#GO:0030424;extracellular region#GO:0005576;cell junction#GO:0030054 membrane-bound signaling molecule#PC00152 Axon guidance mediated by semaphorins#P00007>Sema3A#P00337 MONDO|Ensembl=ENSMODG00000024653.1|UniProtKB=F6XB87 F6XB87 ACTL7B PTHR11937:SF59 ACTIN ACTIN-LIKE PROTEIN 7B structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000021313.3|UniProtKB=F7FPN8 F7FPN8 PTHR10880:SF48 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000006775.3|UniProtKB=A0A5F8GZM6 A0A5F8GZM6 CDH16 PTHR24028:SF1 CADHERIN-87A CADHERIN-16 cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000038553.1|UniProtKB=A0A5F8GM06 A0A5F8GM06 PTHR12044:SF11 BCL2 INTERACTING MEDIATOR OF CELL DEATH SLP ADAPTER AND CSK-INTERACTING MEMBRANE PROTEIN cellular process#GO:0009987;positive regulation of biological process#GO:0048518;organelle organization#GO:0006996;regulation of response to external stimulus#GO:0032101;meiotic cell cycle#GO:0051321;positive regulation of response to external stimulus#GO:0032103;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;regulation of signaling#GO:0023051;nuclear division#GO:0000280;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of response to biotic stimulus#GO:0002833;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;positive regulation of signal transduction#GO:0009967;regulation of response to biotic stimulus#GO:0002831;reproductive process#GO:0022414;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000007889.5|UniProtKB=F6ZGE5 F6ZGE5 IL11RA PTHR23036:SF29 CYTOKINE RECEPTOR INTERLEUKIN-11 RECEPTOR SUBUNIT ALPHA transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375 cytokine-mediated signaling pathway#GO:0019221;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;response to peptide#GO:1901652;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 MONDO|Ensembl=ENSMODG00000043319.1|UniProtKB=A0A5F8G1X1 A0A5F8G1X1 PTHR24070:SF221 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-2A hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of cell motility#GO:2000145;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of locomotion#GO:0040012;small GTPase-mediated signal transduction#GO:0007264;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;regulation of cell migration#GO:0030334 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906 MONDO|Ensembl=ENSMODG00000018745.3|UniProtKB=F7EF59 F7EF59 POLR3C PTHR12949:SF0 RNA POLYMERASE III DNA DIRECTED -RELATED DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000050581.1|UniProtKB=A0A5F8HAV4 A0A5F8HAV4 LOC100028222 PTHR48002:SF122 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4F6 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020620.5|UniProtKB=F6ZAS9 F6ZAS9 NPNT PTHR24050:SF19 PA14 DOMAIN-CONTAINING PROTEIN NEPHRONECTIN MONDO|Ensembl=ENSMODG00000003164.4|UniProtKB=A0A5F8GAI4 A0A5F8GAI4 SELP PTHR19325:SF484 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING P-SELECTIN ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;carboxylic acid binding#GO:0031406;organic acid binding#GO:0043177;carbohydrate binding#GO:0030246;oligosaccharide binding#GO:0070492;carbohydrate derivative binding#GO:0097367 response to peptide#GO:1901652;cell adhesion#GO:0007155;leukocyte migration#GO:0050900;immune system process#GO:0002376;response to cytokine#GO:0034097;response to stimulus#GO:0050896;response to chemical#GO:0042221;cell migration#GO:0016477;cell motility#GO:0048870;leukocyte cell-cell adhesion#GO:0007159;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell-cell adhesion#GO:0098609 side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;complement component#PC00078 MONDO|Ensembl=ENSMODG00000001243.4|UniProtKB=A0A5F8GR18 A0A5F8GR18 FAF1 PTHR23322:SF96 FAS-ASSOCIATED PROTEIN FAS-ASSOCIATED FACTOR 1 DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;ubiquitin binding#GO:0043130;transcription factor binding#GO:0008134;binding#GO:0005488 macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 FAS signaling pathway#P00020>FAF1#P00609 MONDO|Ensembl=ENSMODG00000010532.4|UniProtKB=F6XH11 F6XH11 PTHR24376:SF185 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 786 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000047552.1|UniProtKB=F7EGS5 F7EGS5 LOC100010915 PTHR26453:SF156 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017663.5|UniProtKB=F6YJE9 F6YJE9 PTHR14234:SF21 RIM BINDING PROTEIN-RELATED RIMS-BINDING PROTEIN 3A-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular process#GO:0009987;male gamete generation#GO:0048232;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;gamete generation#GO:0007276;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;fertilization#GO:0009566;reproductive process#GO:0022414;spermatid differentiation#GO:0048515;spermatid development#GO:0007286;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017430.4|UniProtKB=F6ZV92 F6ZV92 BSDC1 PTHR16019:SF5 SYNAPSE-ASSOCIATED PROTEIN BSD DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000050195.1|UniProtKB=A0A5F8G838 A0A5F8G838 TP53TG5 PTHR15562:SF0 TP53-TARGET GENE 5 PROTEIN TP53-TARGET GENE 5 PROTEIN MONDO|Ensembl=ENSMODG00000045963.1|UniProtKB=A0A5F8GK87 A0A5F8GK87 PTHR28582:SF1 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15 MONDO|Ensembl=ENSMODG00000025549.3|UniProtKB=F6UJ46 F6UJ46 PTHR10010:SF23 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;symporter activity#GO:0015293;phosphate transmembrane transporter activity#GO:0005315;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370 cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;localization#GO:0051179;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;phosphate ion transport#GO:0006817;homeostatic process#GO:0042592 cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;apical part of cell#GO:0045177;plasma membrane region#GO:0098590;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;vesicle#GO:0031982;brush border#GO:0005903;cell periphery#GO:0071944 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000046972.1|UniProtKB=F7ATB3 F7ATB3 LOC100013141 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045149.1|UniProtKB=F7D1P0 F7D1P0 LOC100031889 PTHR26453:SF20 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6B9 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002014.4|UniProtKB=F6QXN0 F6QXN0 TIMP2 PTHR11844:SF24 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 2 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162;regulation of catabolic process#GO:0009894;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;response to hormone#GO:0009725;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;response to chemical#GO:0042221;negative regulation of protein catabolic process#GO:0042177;response to cytokine#GO:0034097;biological regulation#GO:0065007;response to peptide#GO:1901652;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000014208.4|UniProtKB=F6WRR2 F6WRR2 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000041074.1|UniProtKB=A0A5F8GEN6 A0A5F8GEN6 ZSWIM7 PTHR28498:SF1 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000009879.4|UniProtKB=F6VD33 F6VD33 PDE6A PTHR11347:SF115 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;retina development in camera-type eye#GO:0060041;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;multicellular organism development#GO:0007275;animal organ development#GO:0048513;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;sensory organ development#GO:0007423;negative regulation of cellular process#GO:0048523;visual system development#GO:0150063;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;system development#GO:0048731;negative regulation of cell communication#GO:0010648;eye development#GO:0001654;negative regulation of intracellular signal transduction#GO:1902532;anatomical structure development#GO:0048856;regulation of signaling#GO:0023051;camera-type eye development#GO:0043010;negative regulation of signaling#GO:0023057;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531 cilium#GO:0005929;cell projection membrane#GO:0031253;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;ciliary membrane#GO:0060170 phosphodiesterase#PC00185;hydrolase#PC00121 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PDEalphabeta#P00759 MONDO|Ensembl=ENSMODG00000012479.4|UniProtKB=F6Q419 F6Q419 PTHR21502:SF2 ZINC FINGER PROTEIN DZIP1 RILP-LIKE PROTEIN 2 binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000013214.3|UniProtKB=A0A5F8H9W3 A0A5F8H9W3 MMP2 PTHR10201:SF29 MATRIX METALLOPROTEINASE 72 KDA TYPE IV COLLAGENASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 extracellular structure organization#GO:0043062;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;cellular component organization#GO:0016043;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896;catabolic process#GO:0009056;tissue remodeling#GO:0048771;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;response to hypoxia#GO:0001666;response to stress#GO:0006950;cellular process#GO:0009987;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 MONDO|Ensembl=ENSMODG00000040432.1|UniProtKB=A0A5F8HJX9 A0A5F8HJX9 SNX10 PTHR46209:SF2 PX DOMAIN-CONTAINING PROTEIN SORTING NEXIN-10 binding#GO:0005488;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;vesicle organization#GO:0016050;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 MONDO|Ensembl=ENSMODG00000003122.4|UniProtKB=A0A5F8G2X3 A0A5F8G2X3 PYCR1 PTHR11645:SF0 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;proteinogenic amino acid biosynthetic process#GO:0170038;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283 reductase#PC00198;metabolite interconversion enzyme#PC00262 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 MONDO|Ensembl=ENSMODG00000039727.1|UniProtKB=H9H8K9 H9H8K9 PTHR26453:SF601 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000597.4|UniProtKB=F6TBG1 F6TBG1 PTPN7 PTHR19134:SF527 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 7 hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 protein phosphatase#PC00195;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000017413.3|UniProtKB=F7AJG4 F7AJG4 PTHR11022:SF12 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN RECOGNITION PROTEIN 3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;signaling receptor activity#GO:0038023;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;peptidoglycan muralytic activity#GO:0061783;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745 defense response to Gram-positive bacterium#GO:0050830;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000016405.4|UniProtKB=F7E8P9 F7E8P9 DOK5 PTHR21258:SF45 DOCKING PROTEIN RELATED DOCKING PROTEIN 5 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000003644.4|UniProtKB=A0A5F8G7L7 A0A5F8G7L7 LOC100017544 PTHR10903:SF199 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000041448.1|UniProtKB=A0A5F8GNZ1 A0A5F8GNZ1 PTHR24404:SF129 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 835 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000018166.4|UniProtKB=F7CCG4 F7CCG4 GRAMD1C PTHR23319:SF1 GRAM DOMAIN CONTAINING 1B, ISOFORM E PROTEIN ASTER-C cholesterol transfer activity#GO:0120020;alcohol binding#GO:0043178;steroid binding#GO:0005496;transporter activity#GO:0005215;sterol transfer activity#GO:0120015;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;cholesterol binding#GO:0015485;small molecule binding#GO:0036094;binding#GO:0005488;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;sterol binding#GO:0032934 organic hydroxy compound transport#GO:0015850;localization#GO:0051179;sterol transport#GO:0015918;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;lipid localization#GO:0010876;intracellular transport#GO:0046907;intracellular sterol transport#GO:0032366;lipid transport#GO:0006869;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;organelle membrane contact site#GO:0044232;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000048025.1|UniProtKB=A0A5F8GA90 A0A5F8GA90 PTHR11435:SF1 NADH UBIQUINONE OXIDOREDUCTASE SUBUNIT ND6 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 6 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000046803.1|UniProtKB=K7E3Q7 K7E3Q7 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000004826.4|UniProtKB=A0A5F8GCJ0 A0A5F8GCJ0 SNX30 PTHR45949:SF1 SORTING NEXIN-4 SORTING NEXIN-30 catabolic process#GO:0009056;endocytic recycling#GO:0032456;piecemeal microautophagy of the nucleus#GO:0034727;cellular localization#GO:0051641;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;macroautophagy#GO:0016236;reticulophagy#GO:0061709;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;establishment of localization#GO:0051234;mitophagy#GO:0000423;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;autophagy of mitochondrion#GO:0000422;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;phagophore assembly site#GO:0000407;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020416.4|UniProtKB=F7BDM3 F7BDM3 MTMR12 PTHR10807:SF37 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 12 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;lipid modification#GO:0030258;dephosphorylation#GO:0016311;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000039161.1|UniProtKB=A0A5F8GCT3 A0A5F8GCT3 IL26 PTHR48482:SF1 INTERLEUKIN-19-RELATED INTERLEUKIN-26 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125 response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;negative regulation of biological process#GO:0048519;cell surface receptor signaling pathway#GO:0007166;negative regulation of response to external stimulus#GO:0032102;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell communication#GO:0007154;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;cytokine-mediated signaling pathway#GO:0019221;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;negative regulation of defense response#GO:0031348;positive regulation of cell communication#GO:0010647;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;immune response#GO:0006955 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000015730.3|UniProtKB=F7B550 F7B550 EMILIN1 PTHR15427:SF1 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMILIN-1 binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;structural molecule activity#GO:0005198 positive regulation of angiogenesis#GO:0045766;positive regulation of cell-substrate adhesion#GO:0010811;regulation of multicellular organismal development#GO:2000026;positive regulation of cell adhesion#GO:0045785;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;cell adhesion#GO:0007155;regulation of angiogenesis#GO:0045765;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of cell adhesion#GO:0030155;regulation of multicellular organismal process#GO:0051239;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;regulation of vasculature development#GO:1901342;cell adhesion mediated by integrin#GO:0033627;positive regulation of developmental process#GO:0051094;regulation of anatomical structure morphogenesis#GO:0022603 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020176.4|UniProtKB=F7GI24 F7GI24 PTHR15298:SF4 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000051179.1|UniProtKB=A0A5F8HJY5 A0A5F8HJY5 SNX11 PTHR46209:SF1 PX DOMAIN-CONTAINING PROTEIN SORTING NEXIN-11 phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000006944.4|UniProtKB=F6RG61 F6RG61 CUL2 PTHR11932:SF174 CULLIN CULLIN-2 protein complex scaffold activity#GO:0140378;enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;structural molecule activity#GO:0005198;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515 primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000004717.4|UniProtKB=F6QGD2 F6QGD2 FLCN PTHR31441:SF4 FOLLICULIN FAMILY MEMBER FOLLICULIN enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 regulation of gene expression#GO:0010468;regulation of TORC1 signaling#GO:1903432;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of TORC1 signaling#GO:1904263;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;positive regulation of TOR signaling#GO:0032008;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000010888.4|UniProtKB=A0A5F8G2L4 A0A5F8G2L4 LOC100017154 PTHR23235:SF77 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 7 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000041648.1|UniProtKB=A0A5F8GKE6 A0A5F8GKE6 SPATA1 PTHR14421:SF3 SPERMATOGENESIS-ASSOCIATED PROTEIN 1 SPERMATOGENESIS-ASSOCIATED PROTEIN 1 MONDO|Ensembl=ENSMODG00000017770.2|UniProtKB=F7DJX8 F7DJX8 STRC PTHR23412:SF14 STEREOCILIN RELATED STEREOCILIN-RELATED cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589 actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862;neuron projection#GO:0043005;cell surface#GO:0009986;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;stereocilium#GO:0032420;membraneless organelle#GO:0043228 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000004929.5|UniProtKB=K7E2Y2 K7E2Y2 PAXIP1 PTHR23196:SF48 PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN PAX-INTERACTING PROTEIN 1 positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;DNA damage response#GO:0006974;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription initiation#GO:2000142;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;cellular response to stress#GO:0033554 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000004034.4|UniProtKB=A0A5F8H2P6 A0A5F8H2P6 HELZ PTHR10887:SF365 DNA2/NAM7 HELICASE FAMILY ATP-DEPENDENT RNA HELICASE WITH ZINC FINGER DOMAIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000025517.4|UniProtKB=A0A5F8G5J8 A0A5F8G5J8 ATXN7 PTHR15117:SF2 ATAXIN 7 RELATED ATAXIN-7 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;microtubule-based process#GO:0007017;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;microtubule cytoskeleton organization#GO:0000226;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000014676.4|UniProtKB=F7E7K9 F7E7K9 SAXO1 PTHR31516:SF9 STABILIZER OF AXONEMAL MICROTUBULES 2 STABILIZER OF AXONEMAL MICROTUBULES 1 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;sperm flagellum#GO:0036126;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;microtubule#GO:0005874;cytoplasmic microtubule#GO:0005881;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000013367.3|UniProtKB=F7DTL3 F7DTL3 CXCR5 PTHR10489:SF618 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 5 protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;chemotaxis#GO:0006935;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000006113.4|UniProtKB=F7EIC0 F7EIC0 TOX4 PTHR45781:SF2 AGAP000281-PA TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 4 DNA binding#GO:0003677;chromatin binding#GO:0003682;chromatin DNA binding#GO:0031490;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 MONDO|Ensembl=ENSMODG00000039486.1|UniProtKB=A0A5F8H0J2 A0A5F8H0J2 PTHR35252:SF1 RETINITIS PIGMENTOSA 9 PROTEIN RETINITIS PIGMENTOSA 9 PROTEIN MONDO|Ensembl=ENSMODG00000012776.4|UniProtKB=F6S1I1 F6S1I1 E2F2 PTHR12081:SF50 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000017509.4|UniProtKB=A0A5F8HJ36 A0A5F8HJ36 SGK1 PTHR24351:SF184 RIBOSOMAL PROTEIN S6 KINASE SERINE_THREONINE-PROTEIN KINASE SGK1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000016110.3|UniProtKB=A0A5F8G3Q3 A0A5F8G3Q3 FAHD1 PTHR11820:SF7 ACYLPYRUVASE OXALOACETATE TAUTOMERASE FAHD1, MITOCHONDRIAL catalytic activity#GO:0003824;hydrolase activity#GO:0016787 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000004214.3|UniProtKB=F6XR43 F6XR43 P2RY10 PTHR24232:SF6 G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 10-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000488.3|UniProtKB=F6U9P9 F6U9P9 SLC35D2 PTHR11132:SF262 SOLUTE CARRIER FAMILY 35 NUCLEOTIDE SUGAR TRANSPORTER SLC35D2 active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;nucleotide-sugar transmembrane transporter activity#GO:0005338;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;carboxylic acid transmembrane transporter activity#GO:0046943 carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nucleotide-sugar transmembrane transport#GO:0015780;nitrogen compound transport#GO:0071705;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000029291.2|UniProtKB=K7E2S0 K7E2S0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013759.3|UniProtKB=F6UBB7 F6UBB7 IFT56 PTHR14781:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 56 INTRAFLAGELLAR TRANSPORT PROTEIN 56 protein-containing complex binding#GO:0044877;binding#GO:0005488 microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;cilium assembly#GO:0060271;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;intraciliary transport involved in cilium assembly#GO:0035735;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;intraciliary transport particle B#GO:0030992;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;ciliary base#GO:0097546 MONDO|Ensembl=ENSMODG00000013676.5|UniProtKB=A0A5F8H177 A0A5F8H177 ALDH16A1 PTHR11699:SF211 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 MONDO|Ensembl=ENSMODG00000013704.4|UniProtKB=A0A5F8GJU8 A0A5F8GJU8 MAPK14 PTHR24055:SF110 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 14 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 FGF signaling pathway#P00021>p38#P00644;EGF receptor signaling pathway#P00018>p38#P00562;B cell activation#P00010>p38#P00384;TGF-beta signaling pathway#P00052>P38#P01275;Gonadotropin-releasing hormone receptor pathway#P06664>p38#P06831;VEGF signaling pathway#P00056>p38MAPK#P01423;JAK/STAT signaling pathway#P00038>Serine kinase#P01029;Parkinson disease#P00049>p38 MAPK#P01212;p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;Oxidative stress response#P00046>p38#P01135;p38 MAPK pathway#P05918>p38alpha#P06031;CCKR signaling map#P06959>p38MAPK#P07079;Toll receptor signaling pathway#P00054>p38#P01352;Angiogenesis#P00005>p38MAPK#P00182;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;CCKR signaling map#P06959>MAPKAP-K2#P07217;Ras Pathway#P04393>p38#P04558 MONDO|Ensembl=ENSMODG00000003051.4|UniProtKB=F6PP28 F6PP28 PTHR45917:SF1 CALCIUM-BINDING PROTEIN 1-RELATED CALCIUM-BINDING PROTEIN 1 transporter regulator activity#GO:0141108;calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;detection of stimulus#GO:0051606;signal transduction#GO:0007165;response to radiation#GO:0009314;cellular process#GO:0009987;system process#GO:0003008;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;visual perception#GO:0007601;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to abiotic stimulus#GO:0009628;sensory perception of light stimulus#GO:0050953;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877 postsynaptic density#GO:0014069;cell junction#GO:0030054;cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020;plasma membrane#GO:0005886;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron to neuron synapse#GO:0098984 MONDO|Ensembl=ENSMODG00000010299.4|UniProtKB=F6SSJ9 F6SSJ9 TFAP2A PTHR10812:SF8 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-ALPHA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of apoptotic process#GO:0042981;multicellular organism development#GO:0007275;animal organ development#GO:0048513;renal system development#GO:0072001;kidney development#GO:0001822;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;skeletal system development#GO:0001501;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of apoptotic process#GO:0043066;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000017245.4|UniProtKB=F6TKX6 F6TKX6 SLC26A5 PTHR11814:SF32 SULFATE TRANSPORTER PRESTIN active transmembrane transporter activity#GO:0022804;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;chloride transmembrane transporter activity#GO:0015108;carboxylic acid transmembrane transporter activity#GO:0046943 cellular process#GO:0009987;dicarboxylic acid transport#GO:0006835;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;multicellular organismal process#GO:0032501;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;chloride transport#GO:0006821;system process#GO:0003008;establishment of localization#GO:0051234;monoatomic anion transport#GO:0006820;sensory perception of sound#GO:0007605;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;nervous system process#GO:0050877;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000014811.4|UniProtKB=F7DLQ1 F7DLQ1 PDIA6 PTHR45815:SF3 PROTEIN DISULFIDE-ISOMERASE A6 PROTEIN DISULFIDE-ISOMERASE A6 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036 response to stimulus#GO:0050896;cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;response to endoplasmic reticulum stress#GO:0034976 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000020720.4|UniProtKB=F7BAB1 F7BAB1 RAP1GDS1 PTHR10957:SF2 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000019906.4|UniProtKB=F6VQ87 F6VQ87 NR1H3 PTHR24082:SF259 NUCLEAR HORMONE RECEPTOR OXYSTEROLS RECEPTOR LXR-ALPHA molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;positive regulation of DNA-templated transcription#GO:0045893;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of gene expression#GO:0010468;cholesterol homeostasis#GO:0042632;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;homeostatic process#GO:0042592;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;negative regulation of defense response#GO:0031348;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of response to external stimulus#GO:0032102;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;chemical homeostasis#GO:0048878;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;lipid homeostasis#GO:0055088;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000010296.3|UniProtKB=F6SSK8 F6SSK8 CILP PTHR15031:SF3 CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP CARTILAGE INTERMEDIATE LAYER PROTEIN 1 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000027500.2|UniProtKB=K7DZJ5 K7DZJ5 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000004268.4|UniProtKB=A0A5F8GLT3 A0A5F8GLT3 FGFR3 PTHR24416:SF505 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 3 transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;kinase activity#GO:0016301;fibroblast growth factor binding#GO:0017134;signaling receptor activity#GO:0038023 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;response to fibroblast growth factor#GO:0071774;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636 MONDO|Ensembl=ENSMODG00000003649.4|UniProtKB=F7AZZ7 F7AZZ7 LOC100027354 PTHR24257:SF19 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 2B serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;cellular process#GO:0009987;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;regulation of platelet aggregation#GO:0090330;proteolysis#GO:0006508;regulation of platelet activation#GO:0010543;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000028521.2|UniProtKB=K7E2S8 K7E2S8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000010261.4|UniProtKB=F6VQ35 F6VQ35 AP3M1 PTHR10529:SF342 AP COMPLEX SUBUNIT MU AP-3 COMPLEX SUBUNIT MU-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;receptor internalization#GO:0031623;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;receptor-mediated endocytosis#GO:0006898;intracellular transport#GO:0046907;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;vacuolar transport#GO:0007034;transport#GO:0006810;Golgi vesicle transport#GO:0048193;endocytosis#GO:0006897;postsynaptic neurotransmitter receptor internalization#GO:0098884;localization#GO:0051179;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;post-Golgi vesicle-mediated transport#GO:0006892;regulation of biological quality#GO:0065008 Golgi apparatus#GO:0005794;AP-type membrane coat adaptor complex#GO:0030119;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000004257.4|UniProtKB=A0A5F8HEN7 A0A5F8HEN7 NGDN PTHR13237:SF9 SOMETHING ABOUT SILENCING PROTEIN 10-RELATED NEUROGUIDIN nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 organelle lumen#GO:0043233;small-subunit processome#GO:0032040;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000015000.4|UniProtKB=F7CFW3 F7CFW3 BZW1 PTHR14208:SF0 BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN EIF5-MIMIC PROTEIN 2 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 MONDO|Ensembl=ENSMODG00000007936.4|UniProtKB=F7G8Z9 F7G8Z9 HEATR1 PTHR13457:SF1 BAP28 HEAT REPEAT-CONTAINING PROTEIN 1 snoRNA binding#GO:0030515;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;regulation of transcription by RNA polymerase I#GO:0006356;rRNA processing#GO:0006364;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of transcription by RNA polymerase I#GO:0045943;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;small-subunit processome#GO:0032040;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000007335.3|UniProtKB=F7EEU7 F7EEU7 COPB1 PTHR10635:SF0 COATOMER SUBUNIT BETA COATOMER SUBUNIT BETA intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;cytoplasm#GO:0005737;COPI-coated vesicle#GO:0030137;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794 vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000001186.4|UniProtKB=A0A5F8G3R8 A0A5F8G3R8 PPP1R21 PTHR21448:SF0 SMOOTH MUSCLE MYOSIN HEAVY CHAIN-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 21 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000002183.4|UniProtKB=F7GEB8 F7GEB8 ANXA1 PTHR10502:SF17 ANNEXIN ANNEXIN A1 ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488;small molecule binding#GO:0036094;lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to steroid hormone#GO:0048545;cellular response to chemical stimulus#GO:0070887;localization#GO:0051179;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;transport#GO:0006810;phagocytosis#GO:0006909;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular response to steroid hormone stimulus#GO:0071383 vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000008592.4|UniProtKB=F7BUF5 F7BUF5 HNRNPUL1 PTHR12381:SF41 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U-LIKE PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000020276.4|UniProtKB=A0A5F8HJ07 A0A5F8HJ07 PAIP1 PTHR23254:SF15 EIF4G DOMAIN PROTEIN POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 1 translation regulator activity#GO:0045182 regulation of translational initiation#GO:0006446;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000039966.1|UniProtKB=A0A5F8GSQ9 A0A5F8GSQ9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000002444.4|UniProtKB=A0A5F8GRX4 A0A5F8GRX4 DIAPH2 PTHR45691:SF3 PROTEIN DIAPHANOUS PROTEIN DIAPHANOUS HOMOLOG 2 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;actin filament#GO:0005884;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>mDia#P00510 MONDO|Ensembl=ENSMODG00000000777.4|UniProtKB=F6SSP4 F6SSP4 STK31 PTHR43289:SF6 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED SERINE_THREONINE KINASE 31 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000000930.4|UniProtKB=F7F820 F7F820 TAPT1 PTHR13317:SF5 TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG regulation of organelle assembly#GO:1902115;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;regulation of cell projection organization#GO:0031344;regulation of cilium assembly#GO:1902017;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component biogenesis#GO:0044087;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;positive regulation of cellular component organization#GO:0051130;positive regulation of cell projection organization#GO:0031346;regulation of cell projection assembly#GO:0060491;positive regulation of organelle organization#GO:0010638 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cilium#GO:0005929;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;endoplasmic reticulum#GO:0005783;ciliary basal body#GO:0036064;endoplasmic reticulum membrane#GO:0005789;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;endomembrane system#GO:0012505;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000047022.1|UniProtKB=A0A5F8GVZ7 A0A5F8GVZ7 PTHR43340:SF6 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE pentosyltransferase activity#GO:0016763;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;magnesium ion binding#GO:0000287;cation binding#GO:0043169;metal ion binding#GO:0046872;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleobase metabolic process#GO:0009112;nucleoside phosphate biosynthetic process#GO:1901293;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;IMP metabolic process#GO:0046040;primary metabolic process#GO:0044238;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247;Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804;Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245 MONDO|Ensembl=ENSMODG00000028672.2|UniProtKB=K7E235 K7E235 LOC103103724 PTHR10206:SF2 CATHELICIDIN CATHELICIDIN ANTIMICROBIAL PEPTIDE lipid binding#GO:0008289;lipopolysaccharide binding#GO:0001530;binding#GO:0005488;carbohydrate derivative binding#GO:0097367 biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;defense response to Gram-positive bacterium#GO:0050830;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051 MONDO|Ensembl=ENSMODG00000049556.1|UniProtKB=F7DXY9 F7DXY9 PTHR48018:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 974 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001493.4|UniProtKB=A0A5F8GC78 A0A5F8GC78 DENND2D PTHR15288:SF2 DENN DOMAIN-CONTAINING PROTEIN 2 DENN DOMAIN-CONTAINING PROTEIN 2D GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000012187.4|UniProtKB=F7CXX6 F7CXX6 GFRA3 PTHR10269:SF15 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;nervous system development#GO:0007399;system development#GO:0048731 signaling receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010822.4|UniProtKB=F7BZ92 F7BZ92 BRF2 PTHR11618:SF5 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION FACTOR IIIB 50 KDA SUBUNIT protein binding#GO:0005515;binding#GO:0005488;transcription factor binding#GO:0008134 transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 general transcription factor#PC00259 General transcription regulation#P00023>TFIIB#P00668;Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397 MONDO|Ensembl=ENSMODG00000040474.1|UniProtKB=A0A5F8GQV1 A0A5F8GQV1 VN2R551 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000017058.3|UniProtKB=F6XHU5 F6XHU5 TCEA2 PTHR11477:SF3 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 2 transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000006553.3|UniProtKB=F7BUW7 F7BUW7 DVL2 PTHR10878:SF8 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-2 G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 biological regulation#GO:0065007;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dsh#P00200;Wnt signaling pathway#P00057>Dishevelled#P01447;Alzheimer disease-presenilin pathway#P00004>Dsh#P00132 MONDO|Ensembl=ENSMODG00000022903.2|UniProtKB=F6Q0V7 F6Q0V7 PTHR10677:SF9 UBIQUILIN UBIQUILIN-LIKE PROTEIN protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;binding#GO:0005488 catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010719.4|UniProtKB=F7G7M7 F7G7M7 ADCK5 PTHR43173:SF28 ABC1 FAMILY PROTEIN AARF DOMAIN CONTAINING KINASE 5 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000023035.2|UniProtKB=F6S140 F6S140 PTHR13947:SF48 GNAT FAMILY N-ACETYLTRANSFERASE N-ACETYLTRANSFERASE 8-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000048684.1|UniProtKB=A0A5F8H8U3 A0A5F8H8U3 LOC100026687 PTHR42748:SF10 NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER NMRA-LIKE FAMILY DOMAIN-CONTAINING PROTEIN 1 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000041714.1|UniProtKB=A0A5F8G7W0 A0A5F8G7W0 PIRT PTHR16100:SF4 PHOSPHOINOSITIDE-INTERACTING PROTEIN FAMILY MEMBER PHOSPHOINOSITIDE-INTERACTING PROTEIN protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;transmembrane transporter binding#GO:0044325 biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of biological process#GO:0050789;regulation of system process#GO:0044057 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000006749.3|UniProtKB=F7CCS4 F7CCS4 MYOD1 PTHR11534:SF2 MYOGENIC FACTOR MYOBLAST DETERMINATION PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;animal organ development#GO:0048513;positive regulation of cell differentiation#GO:0045597;striated muscle tissue development#GO:0014706;muscle organ development#GO:0007517;regulation of developmental process#GO:0050793;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;muscle tissue development#GO:0060537;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;tissue development#GO:0009888;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell development#GO:0060284;skeletal muscle tissue development#GO:0007519;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000025484.3|UniProtKB=A0A5F8HGI4 A0A5F8HGI4 GTF2F2 PTHR10445:SF0 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367 RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription regulation#P00023>TFIIFbeta#P00667;Transcription regulation by bZIP transcription factor#P00055>TFIIFbeta#P01396 MONDO|Ensembl=ENSMODG00000036372.1|UniProtKB=K7E0M3 K7E0M3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008345.5|UniProtKB=F6UPU9 F6UPU9 PTHR10098:SF108 RAPSYN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 28 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000040715.1|UniProtKB=A0A5F8G4T0 A0A5F8G4T0 CLDN10 PTHR12002:SF13 CLAUDIN CLAUDIN-10 transporter activity#GO:0005215;paracellular tight junction channel activity#GO:0160187 transport#GO:0006810;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;paracellular transport#GO:0160184;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell junction organization#GO:0034330;cellular component assembly#GO:0022607 cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;apical junction complex#GO:0043296;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000049231.1|UniProtKB=A0A5F8H6S9 A0A5F8H6S9 PEAK3 PTHR22972:SF6 SERINE/THREONINE PROTEIN KINASE PROTEIN PEAK3 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of biological process#GO:0050789;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell motility#GO:2000145 actin cytoskeleton#GO:0015629;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;membraneless organelle#GO:0043228 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000019158.2|UniProtKB=F7BK30 F7BK30 B3GNT3 PTHR11214:SF405 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 3 glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;aminoglycan biosynthetic process#GO:0006023;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000036577.1|UniProtKB=F7FAE4 F7FAE4 PTHR45885:SF6 CELL DIVISION CYCLE 5-LIKE PROTEIN CELL DIVISION CYCLE 5-LIKE PROTEIN transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions#GO:0000375;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;regulation of transcription by RNA polymerase II#GO:0006357;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987 spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000001883.4|UniProtKB=F6RYT7 F6RYT7 PTHR24276:SF62 POLYSERASE-RELATED POLYSERASE-2 catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 serine protease#PC00203;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000003133.2|UniProtKB=F6WUZ7 F6WUZ7 DYNLL1 PTHR11886:SF91 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN-RELATED binding#GO:0005488;protein binding#GO:0005515 microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;cilium assembly#GO:0060271;cellular component organization#GO:0016043;intraciliary transport#GO:0042073;intraciliary retrograde transport#GO:0035721;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;dynein complex#GO:0030286;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000043132.1|UniProtKB=A0A5F8HCQ7 A0A5F8HCQ7 HES1 PTHR10985:SF153 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;anterior/posterior pattern specification#GO:0009952;regulation of multicellular organismal process#GO:0051239;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;Notch signaling pathway#GO:0007219;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of neuron differentiation#GO:0045664;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 MONDO|Ensembl=ENSMODG00000044114.1|UniProtKB=A0A5F8H2G2 A0A5F8H2G2 PTHR26453:SF57 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T6 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028745.2|UniProtKB=K7E3T8 K7E3T8 LOC103102293 PTHR47499:SF4 SERINE PROTEASE INHIBITOR KAZAL-TYPE 7 SPINK7 SERINE PROTEASE INHIBITOR KAZAL-TYPE 12 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414 negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000016675.4|UniProtKB=A0A5F8H1L8 A0A5F8H1L8 CDH4 PTHR24027:SF81 CADHERIN-23 CADHERIN-4 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell motility#GO:0048870;cell migration#GO:0016477;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000002650.4|UniProtKB=F7DI96 F7DI96 SLC5A7 PTHR45897:SF2 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH AFFINITY CHOLINE TRANSPORTER 1 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324 establishment of localization#GO:0051234;metabolic process#GO:0008152;neuromuscular synaptic transmission#GO:0007274;transport#GO:0006810;synaptic transmission, cholinergic#GO:0007271;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;biosynthetic process#GO:0009058;synaptic signaling#GO:0099536;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;cell communication#GO:0007154;localization#GO:0051179;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789 dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;cell body#GO:0044297;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;synapse#GO:0045202;perikaryon#GO:0043204;cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886 transporter#PC00227 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084;Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072 MONDO|Ensembl=ENSMODG00000046008.1|UniProtKB=A0A5F8GQH5 A0A5F8GQH5 SPOP PTHR24413:SF97 SPECKLE-TYPE POZ PROTEIN SPECKLE-TYPE POZ PROTEIN protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of proteolysis#GO:0030162;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000002529.4|UniProtKB=A0A5F8GGB6 A0A5F8GGB6 PPP4R3A PTHR23318:SF3 ATP SYNTHASE GAMMA-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3A enzyme activator activity#GO:0008047;protein phosphatase regulator activity#GO:0019888;phosphatase activator activity#GO:0019211;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;DNA damage response#GO:0006974;regulation of response to stress#GO:0080134;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to stress#GO:0033554;regulation of cellular response to stress#GO:0080135;regulation of double-strand break repair#GO:2000779;regulation of DNA metabolic process#GO:0051052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleoplasm#GO:0005654 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000014162.4|UniProtKB=F6UN36 F6UN36 HTR3B PTHR18945:SF53 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3B ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324 synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;transport#GO:0006810;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;metal ion transport#GO:0030001;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;trans-synaptic signaling#GO:0099537 cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 5HT3 type receptor mediated signaling pathway#P04375>5HT3 Rec#P04422 MONDO|Ensembl=ENSMODG00000012962.2|UniProtKB=F7DC81 F7DC81 BSX PTHR24327:SF35 HOMEOBOX PROTEIN BRAIN-SPECIFIC HOMEOBOX PROTEIN HOMOLOG nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;maintenance of cell number#GO:0098727;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;feeding behavior#GO:0007631;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;stem cell population maintenance#GO:0019827;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000039817.1|UniProtKB=F6S985 F6S985 LOC100020689 PTHR48002:SF60 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017121.4|UniProtKB=F6U405 F6U405 ADAM15 PTHR11905:SF130 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 15 signaling receptor binding#GO:0005102;binding#GO:0005488;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;catalytic activity#GO:0003824;cell adhesion molecule binding#GO:0050839;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;integrin binding#GO:0005178;metalloendopeptidase activity#GO:0004222 proteolysis#GO:0006508;immune system process#GO:0002376;protein metabolic process#GO:0019538;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological regulation#GO:0065007;defense response to other organism#GO:0098542 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000005042.4|UniProtKB=F7BES5 F7BES5 HTR2C PTHR24247:SF32 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2C G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227 synaptic signaling#GO:0099536;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698 cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414 MONDO|Ensembl=ENSMODG00000028578.2|UniProtKB=K7E3F4 K7E3F4 LOC103093164 PTHR11860:SF121 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 8 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000001810.4|UniProtKB=F6T5U1 F6T5U1 PRSS53 PTHR24276:SF61 POLYSERASE-RELATED SERINE PROTEASE 53 catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein modifying enzyme#PC00260;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000038122.1|UniProtKB=F7FMX4 F7FMX4 PTHR45632:SF11 LD33804P KELCH-LIKE PROTEIN 13 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell cycle#GO:0051726;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 transferase complex#GO:1990234;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005448.2|UniProtKB=F7CH12 F7CH12 PTHR33668:SF3 PROTEIN BRICK1 PROTEIN BRICK1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;regulation of anatomical structure size#GO:0090066;regulation of actin nucleation#GO:0051125;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;positive regulation of cell projection organization#GO:0031346;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of cell projection assembly#GO:0060491;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component biogenesis#GO:0044087 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000006508.4|UniProtKB=F7EJY9 F7EJY9 TLX3 PTHR45921:SF1 IP01054P T-CELL LEUKEMIA HOMEOBOX PROTEIN 3 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000012782.4|UniProtKB=A0A5F8HBV7 A0A5F8HBV7 PKP2 PTHR10372:SF25 PLAKOPHILLIN-RELATED PLAKOPHILIN-2 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 intermediate filament cytoskeleton organization#GO:0045104;circulatory system development#GO:0072359;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;cellular localization#GO:0051641;intermediate filament organization#GO:0045109;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;heart development#GO:0007507;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;intermediate filament bundle assembly#GO:0045110;protein localization to cell periphery#GO:1990778;cell junction organization#GO:0034330;protein localization to plasma membrane#GO:0072659;supramolecular fiber organization#GO:0097435;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;localization within membrane#GO:0051668;multicellular organismal process#GO:0032501;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;developmental process#GO:0032502;cell-cell junction organization#GO:0045216 cell junction#GO:0030054;adherens junction#GO:0005912;cell-cell contact zone#GO:0044291;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intercalated disc#GO:0014704;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 intermediate filament binding protein#PC00130;intermediate filament#PC00129;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000020360.4|UniProtKB=A0A5F8HAA5 A0A5F8HAA5 TMEM138 PTHR13306:SF6 TRANSMEMBRANE PROTEIN 138 TRANSMEMBRANE PROTEIN 138 cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000012747.3|UniProtKB=F6T0H1 F6T0H1 BDKRB1 PTHR24228:SF28 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR B1 BRADYKININ RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 MONDO|Ensembl=ENSMODG00000006464.4|UniProtKB=F7FGS3 F7FGS3 FBXW11 PTHR44156:SF9 SUPERNUMERARY LIMBS, ISOFORM B-RELATED F-BOX AND WD REPEAT DOMAIN CONTAINING 11 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;regulation of proteasomal protein catabolic process#GO:0061136;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;regulation of protein catabolic process#GO:0042176;protein metabolic process#GO:0019538 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461 Hedgehog signaling pathway#P00025>Slimb#P00683;Wnt signaling pathway#P00057>betaTrCP#P01454;Parkinson disease#P00049>hSel10#P01240 MONDO|Ensembl=ENSMODG00000010166.4|UniProtKB=A0A5F8H1G5 A0A5F8H1G5 HDAC6 PTHR10625:SF21 HISTONE DEACETYLASE HDAC1-RELATED PROTEIN DEACETYLASE HDAC6 histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity#GO:0003824 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;chromatin organization#GO:0006325 cytoplasm#GO:0005737;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000017289.5|UniProtKB=A0A5F8H694 A0A5F8H694 ABCA2 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810;establishment of localization#GO:0051234;lipid transport#GO:0006869;localization#GO:0051179 intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000019462.4|UniProtKB=F6RWM1 F6RWM1 POFUT1 PTHR21420:SF3 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1 protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neurotic#P01115 MONDO|Ensembl=ENSMODG00000036931.1|UniProtKB=A0A5F8H3Z8 A0A5F8H3Z8 GPR150 PTHR24241:SF83 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 150-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000005915.5|UniProtKB=A0A5F8G7F9 A0A5F8G7F9 GOLGA2 PTHR10881:SF46 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 2 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000037336.1|UniProtKB=A0A5F8GCV4 A0A5F8GCV4 SOST PTHR14903:SF4 SCLEROSTIN-RELATED SCLEROSTIN binding#GO:0005488;protein binding#GO:0005515;cytokine binding#GO:0019955 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of BMP signaling pathway#GO:0030514;regulation of BMP signaling pathway#GO:0030510;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789;ossification#GO:0001503;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000025234.3|UniProtKB=F7B3M3 F7B3M3 PTHR24377:SF980 IP01015P-RELATED ZINC FINGER PROTEIN 420 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014474.4|UniProtKB=F7A5B7 F7A5B7 MKLN1 PTHR15526:SF5 MUSKELIN MUSKELIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000017226.3|UniProtKB=F6WXM4 F6WXM4 PPIH PTHR11071:SF602 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE H intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000042386.1|UniProtKB=A0A5F8HIY5 A0A5F8HIY5 LOC103105522 PTHR15498:SF73 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN CONTAINING TIM HEPATITIS A VIRUS CELLULAR RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 positive regulation of innate immune response#GO:0045089;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;activation of innate immune response#GO:0002218;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stress#GO:0080134;pattern recognition receptor signaling pathway#GO:0002221;regulation of gene expression#GO:0010468;positive regulation of response to biotic stimulus#GO:0002833;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;regulation of response to biotic stimulus#GO:0002831;intracellular receptor signaling pathway#GO:0030522;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;immune system process#GO:0002376;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753 membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000037352.1|UniProtKB=A0A5F8GEZ2 A0A5F8GEZ2 PTHR11758:SF16 40S RIBOSOMAL PROTEIN S15A SMALL RIBOSOMAL SUBUNIT PROTEIN US8 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000016858.4|UniProtKB=A0A5F8G3U4 A0A5F8G3U4 PHYH PTHR21308:SF1 PHYTANOYL-COA ALPHA-HYDROXYLASE PHYTANOYL-COA DIOXYGENASE, PEROXISOMAL dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;peroxisome#GO:0005777 metabolite interconversion enzyme#PC00262;hydroxylase#PC00122 MONDO|Ensembl=ENSMODG00000004854.3|UniProtKB=F6U4M1 F6U4M1 KCNG4 PTHR11537:SF167 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL REGULATORY SUBUNIT KCNG4 potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;metal ion transport#GO:0030001;action potential#GO:0001508 cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165 voltage-gated ion channel#PC00241;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000008183.4|UniProtKB=F7E4D6 F7E4D6 KLHL23 PTHR24412:SF304 KELCH PROTEIN KELCH-LIKE PROTEIN 23 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000023661.2|UniProtKB=A0A5F8H9J0 A0A5F8H9J0 GPR4 PTHR24234:SF10 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000008436.4|UniProtKB=F7AKF5 F7AKF5 RBM34 PTHR23236:SF25 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H RNA-BINDING PROTEIN 34 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000011436.3|UniProtKB=F6RJU3 F6RJU3 PTHR10677:SF10 UBIQUILIN UBIQUILIN-LIKE PROTEIN protein binding#GO:0005515;modification-dependent protein binding#GO:0140030;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000047009.1|UniProtKB=A0A5F8GEZ1 A0A5F8GEZ1 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000012002.3|UniProtKB=F7B8Y1 F7B8Y1 PTHR45880:SF1 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;U2 snRNP#GO:0005686;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681 MONDO|Ensembl=ENSMODG00000004037.3|UniProtKB=F7CME1 F7CME1 LOC100031849 PTHR18884:SF50 SEPTIN SEPTIN-10 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cell cycle#GO:0007049;cell cycle process#GO:0022402;cell division#GO:0051301;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000039417.1|UniProtKB=F7BX16 F7BX16 LOC100618665 PTHR26453:SF116 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2F1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009548.4|UniProtKB=F7BK04 F7BK04 MPPED2 PTHR12905:SF13 METALLOPHOSPHOESTERASE METALLOPHOSPHOESTERASE MPPED2 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 MONDO|Ensembl=ENSMODG00000012220.4|UniProtKB=A0A5F8GX50 A0A5F8GX50 PTHR37456:SF5 SI:CH211-266K2.1 COLLAGEN TYPE XIII ALPHA 1 CHAIN MONDO|Ensembl=ENSMODG00000008605.4|UniProtKB=A0A5F8GQ98 A0A5F8GQ98 PTHR15427:SF23 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMI DOMAIN-CONTAINING PROTEIN 1 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cell-substrate adhesion#GO:0010811;positive regulation of cell adhesion#GO:0045785;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000016417.4|UniProtKB=H9H6U7 H9H6U7 LOC100027598 PTHR12103:SF19 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING 2 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181;hydrolase#PC00121;nucleotide phosphatase#PC00173 MONDO|Ensembl=ENSMODG00000011429.2|UniProtKB=F6RKE3 F6RKE3 LOC100022691 PTHR26450:SF132 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR OLFR654 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027673.2|UniProtKB=A0A5F8GYZ7 A0A5F8GYZ7 CELF3 PTHR24012:SF739 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 3 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of mRNA splicing, via spliceosome#GO:0048024;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions#GO:0000375;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of RNA splicing#GO:0043484;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000049633.1|UniProtKB=A0A5F8GK13 A0A5F8GK13 SBK1 PTHR24359:SF0 SERINE/THREONINE-PROTEIN KINASE SBK1 SERINE_THREONINE-PROTEIN KINASE SBK1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000003943.4|UniProtKB=F7FZ67 F7FZ67 TAF2 PTHR15137:SF9 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170 RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 MONDO|Ensembl=ENSMODG00000005925.4|UniProtKB=F6WX46 F6WX46 ALG1 PTHR13036:SF0 BETA1,4 MANNOSYLTRANSFERASE CHITOBIOSYLDIPHOSPHODOLICHOL BETA-MANNOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000019789.3|UniProtKB=F6TAA3 F6TAA3 LMX1B PTHR24208:SF96 LIM/HOMEOBOX PROTEIN LHX LIM HOMEOBOX TRANSCRIPTION FACTOR 1-BETA transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000021216.4|UniProtKB=F6UGH9 F6UGH9 SLC19A3 PTHR10686:SF37 FOLATE TRANSPORTER THIAMINE TRANSPORTER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000015845.4|UniProtKB=F7DUX6 F7DUX6 TFEC PTHR45776:SF1 MIP04163P TRANSCRIPTION FACTOR EC cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000008894.3|UniProtKB=A0A5F8GQB8 A0A5F8GQB8 PTHR48001:SF115 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1S1-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040256.1|UniProtKB=A0A5F8H8T7 A0A5F8H8T7 VN2R614 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000008335.3|UniProtKB=F6S950 F6S950 PITPNA PTHR10658:SF28 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PHOSPHATIDYLINOSITOL TRANSFER PROTEIN ALPHA ISOFORM phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol transfer activity#GO:0008526;phosphatidylcholine binding#GO:0031210;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylcholine intramembrane carrier activity#GO:0008525;lipid carrier activity#GO:0005319;cation binding#GO:0043169;intramembrane lipid carrier activity#GO:0140303;transporter activity#GO:0005215;binding#GO:0005488;molecular carrier activity#GO:0140104;lipid binding#GO:0008289;lipid transfer activity#GO:0120013 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000016588.4|UniProtKB=A0A5F8G2M1 A0A5F8G2M1 PTHR19288:SF44 4-NITROPHENYLPHOSPHATASE-RELATED PHOSPHOLYSINE PHOSPHOHISTIDINE INORGANIC PYROPHOSPHATE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity, acting on acid anhydrides#GO:0016817;phosphatase activity#GO:0016791 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000000998.4|UniProtKB=F7DNE7 F7DNE7 PTHR47538:SF1 PERILIPIN 4 PERILIPIN-4 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000046351.1|UniProtKB=A0A5F8H910 A0A5F8H910 PROK1 PTHR18821:SF7 PROKINETICIN PROKINETICIN-1 endothelial cell proliferation#GO:0001935;epithelial cell proliferation#GO:0050673;cell population proliferation#GO:0008283;cellular process#GO:0009987 peptide hormone#PC00179 MONDO|Ensembl=ENSMODG00000015539.4|UniProtKB=A0A5F8H9U3 A0A5F8H9U3 TOGARAM2 PTHR21567:SF42 CLASP TOG ARRAY REGULATOR OF AXONEMAL MICROTUBULES PROTEIN 2 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;microtubule#GO:0005874;cytoplasmic microtubule#GO:0005881;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000050983.1|UniProtKB=A0A5F8G9C7 A0A5F8G9C7 PTHR13738:SF2 TROPONIN I TROPONIN I, CARDIAC MUSCLE cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 heart process#GO:0003015;muscle system process#GO:0003012;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;nervous system process#GO:0050877;muscle contraction#GO:0006936;neuromuscular process#GO:0050905;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;heart contraction#GO:0060047;system process#GO:0003008 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;sarcomere#GO:0030017;contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000010174.3|UniProtKB=F6TA21 F6TA21 YWHAE PTHR18860:SF176 14-3-3 PROTEIN 14-3-3 PROTEIN EPSILON binding#GO:0005488;protein binding#GO:0005515 biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;EGF receptor signaling pathway#P00018>14-3-3#P00539;FGF signaling pathway#P00021>14-3-3#P00624 MONDO|Ensembl=ENSMODG00000019419.4|UniProtKB=F6SYH6 F6SYH6 MARVELD2 PTHR23288:SF3 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL MARVEL DOMAIN-CONTAINING PROTEIN 2 transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;positive regulation of RNA metabolic process#GO:0051254;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;snRNA metabolic process#GO:0016073;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;transcription by RNA polymerase II#GO:0006366;cell-cell junction organization#GO:0045216;snRNA transcription#GO:0009301;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;nucleic acid biosynthetic process#GO:0141187;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cell-cell junction assembly#GO:0007043 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;bicellular tight junction#GO:0005923;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;cell-cell junction#GO:0005911;nucleus#GO:0005634;cell periphery#GO:0071944;tight junction#GO:0070160;nuclear protein-containing complex#GO:0140513;cell junction#GO:0030054;apical junction complex#GO:0043296;apical part of cell#GO:0045177;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;organelle lumen#GO:0043233;apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708;vesicle#GO:0031982;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000037195.1|UniProtKB=A0A5F8GYN1 A0A5F8GYN1 MED18 PTHR13321:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 18 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 18 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription initiation#GO:2000142;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000038298.1|UniProtKB=A0A5F8HFX3 A0A5F8HFX3 PTHR12876:SF28 N4BP1-RELATED PROTEIN KHNYN catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;nuclease activity#GO:0004518;RNA binding#GO:0003723 positive regulation of mRNA catabolic process#GO:0061014;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000041349.1|UniProtKB=A0A5F8GF89 A0A5F8GF89 GM2A PTHR17357:SF0 GM2 GANGLIOSIDE ACTIVATOR PROTEIN GANGLIOSIDE GM2 ACTIVATOR lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;localization#GO:0051179;lipid localization#GO:0010876;lipid transport#GO:0006869;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid metabolic process#GO:0006629;transport#GO:0006810;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000004100.4|UniProtKB=F6VFF2 F6VFF2 STT3A PTHR13872:SF43 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3A catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000042278.1|UniProtKB=A0A5F8GTY9 A0A5F8GTY9 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000014958.4|UniProtKB=K7E4P4 K7E4P4 SIAH3 PTHR45877:SF5 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 SEVEN IN ABSENTIA HOMOLOG 3 protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000040449.1|UniProtKB=A0A5F8G7N6 A0A5F8G7N6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000049276.1|UniProtKB=A0A5F8H5H3 A0A5F8H5H3 LOC100619972 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018074.4|UniProtKB=A0A5F8H2E2 A0A5F8H2E2 RETNLB PTHR21101:SF13 RESISTIN RESISTIN-LIKE BETA signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 epithelial cell proliferation#GO:0050673;cellular process#GO:0009987;cell population proliferation#GO:0008283 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000024287.2|UniProtKB=Q2AB84 Q2AB84 T2R62 PTHR11394:SF69 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 134 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016722.3|UniProtKB=A0A5F8H6Y4 A0A5F8H6Y4 SGCE PTHR10132:SF17 ALPHA-/EPSILON-SARCOGLYCAN FAMILY MEMBER EPSILON-SARCOGLYCAN cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 cadherin#PC00057 MONDO|Ensembl=ENSMODG00000022826.3|UniProtKB=H9H9E3 H9H9E3 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010051.3|UniProtKB=F6TCY0 F6TCY0 PTHR22812:SF162 CHROMOBOX PROTEIN CHROMOBOX 3 binding#GO:0005488;chromatin binding#GO:0003682 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular component assembly#GO:0022607;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987 intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000023074.3|UniProtKB=F7G1M3 F7G1M3 CEBPZ PTHR12048:SF0 CCAAT-BINDING FACTOR-RELATED CCAAT_ENHANCER-BINDING PROTEIN ZETA nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000006415.4|UniProtKB=F7FCU7 F7FCU7 VPS13B PTHR12517:SF0 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 13B INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13B membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000039842.1|UniProtKB=F7DM99 F7DM99 LOC100618906 PTHR26453:SF712 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10H1-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048278.1|UniProtKB=A0A5F8H4F7 A0A5F8H4F7 PTHR26453:SF156 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004286.3|UniProtKB=F6TDR6 F6TDR6 TAF6 PTHR10221:SF9 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;transferase complex#GO:1990234;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP#P00670;General transcription regulation#P00023>TBP-associated factors#P00658 MONDO|Ensembl=ENSMODG00000009635.4|UniProtKB=F6QTU7 F6QTU7 ST18 PTHR10816:SF9 MYELIN TRANSCRIPTION FACTOR 1-RELATED SUPPRESSION OF TUMORIGENICITY 18 PROTEIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000012662.4|UniProtKB=A0A5F8HG93 A0A5F8HG93 PTHR48207:SF3 SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE SUCCINYL-COA:GLUTARATE COA-TRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 Carnitine metabolism#P02733>Carnitine dehydratase#P02866;Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864 MONDO|Ensembl=ENSMODG00000007337.4|UniProtKB=A0A5F8GS28 A0A5F8GS28 CLEC4E PTHR22802:SF402 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER E binding#GO:0005488;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;signaling receptor activity#GO:0038023 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000019638.4|UniProtKB=F6XPF6 F6XPF6 CWC27 PTHR45625:SF6 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED SPLICEOSOME-ASSOCIATED PROTEIN CWC27 HOMOLOG catalytic activity#GO:0003824;cis-trans isomerase activity#GO:0016859;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;catalytic activity, acting on a protein#GO:0140096 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000006874.4|UniProtKB=F6PWX1 F6PWX1 HTR7 PTHR24247:SF116 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 7 G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 MONDO|Ensembl=ENSMODG00000047340.1|UniProtKB=A0A5F8GLU4 A0A5F8GLU4 KCTD15 PTHR14499:SF27 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD15 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000041962.1|UniProtKB=A0A5F8HKT4 A0A5F8HKT4 LOC100018857 PTHR26450:SF141 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006296.3|UniProtKB=A0A5F8HE51 A0A5F8HE51 CPTP PTHR10219:SF20 GLYCOLIPID TRANSFER PROTEIN-RELATED CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;phospholipid transfer activity#GO:0120014;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;phospholipid binding#GO:0005543;transporter activity#GO:0005215 transport#GO:0006810;lipid localization#GO:0010876;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;membrane organization#GO:0061024;ceramide transport#GO:0035627;lipid transport#GO:0006869 cytosol#GO:0005829;membrane#GO:0016020;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000011681.4|UniProtKB=A0A5F8HF90 A0A5F8HF90 OGA PTHR13170:SF16 O-GLCNACASE PROTEIN O-GLCNACASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000002592.3|UniProtKB=F7G4Y2 F7G4Y2 PTHR11596:SF30 ALKALINE PHOSPHATASE INTESTINAL-TYPE ALKALINE PHOSPHATASE catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000028982.2|UniProtKB=K7E134 K7E134 PTHR19331:SF458 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN SCART1 cargo receptor activity#GO:0038024 multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;hemopoiesis#GO:0030097;T cell differentiation#GO:0030217;cellular process#GO:0009987;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell differentiation#GO:0030154;cell development#GO:0048468;leukocyte differentiation#GO:0002521;T cell activation#GO:0042110;leukocyte activation#GO:0045321;mononuclear cell differentiation#GO:1903131;anatomical structure development#GO:0048856;cell fate commitment#GO:0045165;immune system process#GO:0002376;cell activation#GO:0001775;lymphocyte differentiation#GO:0030098 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000019345.4|UniProtKB=H9H7B6 H9H7B6 ZNF574 PTHR24377:SF770 IP01015P-RELATED ZINC FINGER PROTEIN 526 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000023670.3|UniProtKB=F6VXQ5 F6VXQ5 PTHR24376:SF245 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 585A gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016468.5|UniProtKB=H9H6V5 H9H6V5 DLX5 PTHR24327:SF31 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;embryo development ending in birth or egg hatching#GO:0009792;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;developmental process#GO:0032502;embryo development#GO:0009790;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000014290.4|UniProtKB=A0A5F8GXU5 A0A5F8GXU5 KLHL22 PTHR45632:SF5 LD33804P KELCH-LIKE PROTEIN 22 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017792.4|UniProtKB=F7CZE6 F7CZE6 CEP85L PTHR31075:SF2 CENTROSOMAL PROTEIN OF 85 KDA CENTROSOMAL PROTEIN OF 85 KDA-LIKE intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000010281.4|UniProtKB=F6VNS7 F6VNS7 PTHR11920:SF500 GUANYLYL CYCLASE GUANYLATE CYCLASE 2G peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;molecular transducer activity#GO:0060089;lyase activity#GO:0016829 ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;cell communication#GO:0007154;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 lyase#PC00144;guanylate cyclase#PC00114 MONDO|Ensembl=ENSMODG00000024642.1|UniProtKB=F6XCC1 F6XCC1 LOC100029204 PTHR23212:SF0 BRAIN ACID SOLUBLE PROTEIN 1 BRAIN ACID SOLUBLE PROTEIN 1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000042253.1|UniProtKB=A0A5F8H9Z0 A0A5F8H9Z0 ZNF775 PTHR24377:SF614 IP01015P-RELATED ZINC FINGER PROTEIN 775 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016079.3|UniProtKB=F7G9H8 F7G9H8 PTHR15854:SF4 THAP4 PROTEIN PEROXYNITRITE ISOMERASE THAP4 MONDO|Ensembl=ENSMODG00000000686.5|UniProtKB=F6WM34 F6WM34 DEPDC1 PTHR16206:SF12 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 1A regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000015171.4|UniProtKB=F7CEM7 F7CEM7 POLE PTHR10670:SF0 DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A DNA-directed DNA polymerase activity#GO:0003887;hydrolase activity#GO:0016787;DNA nuclease activity#GO:0004536;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;DNA exonuclease activity#GO:0004529;transferase activity#GO:0016740;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170 intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;epsilon DNA polymerase complex#GO:0008622;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;chromosome#GO:0005694;organelle lumen#GO:0043233 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000013603.4|UniProtKB=F6VVK5 F6VVK5 IRF3 PTHR11949:SF1 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 3 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 Toll receptor signaling pathway#P00054>IRF3#P01374 MONDO|Ensembl=ENSMODG00000041003.1|UniProtKB=F7EVM8 F7EVM8 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005384.3|UniProtKB=A0A5F8H7F9 A0A5F8H7F9 JAM3 PTHR44598:SF2 JUNCTIONAL ADHESION MOLECULE C JUNCTIONAL ADHESION MOLECULE C cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000051124.1|UniProtKB=A0A5F8G410 A0A5F8G410 SPAG1 PTHR45984:SF3 RNA (RNA) POLYMERASE II ASSOCIATED PROTEIN HOMOLOG SPERM-ASSOCIATED ANTIGEN 1 binding#GO:0005488;heat shock protein binding#GO:0031072;protein binding#GO:0005515 intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179;protein localization to mitochondrion#GO:0070585;macromolecule localization#GO:0033036 cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000013473.4|UniProtKB=F7FML1 F7FML1 GPC1 PTHR10822:SF8 GLYPICAN GLYPICAN-1 fibroblast growth factor binding#GO:0017134;protein binding#GO:0005515;growth factor binding#GO:0019838;binding#GO:0005488 negative regulation of cell communication#GO:0010648;regulation of protein localization#GO:0032880;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;cell migration#GO:0016477;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of protein localization to membrane#GO:1905475 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell junction#GO:0030054;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;synapse#GO:0045202 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000049455.1|UniProtKB=A0A5F8H371 A0A5F8H371 monDomV1R1270 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006666.4|UniProtKB=A0A5F8HGC6 A0A5F8HGC6 MERTK PTHR24416:SF257 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE MER kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;cell motility#GO:0048870;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;localization#GO:0051179;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell migration#GO:0016477;developmental process#GO:0032502;transport#GO:0006810;cell surface receptor signaling pathway#GO:0007166;phagocytosis#GO:0006909;multicellular organism development#GO:0007275;establishment of localization#GO:0051234;import into cell#GO:0098657 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015296.3|UniProtKB=F6QDI3 F6QDI3 MLANA PTHR15305:SF0 MELANOMA ANTIGEN RECOGNIZED BY T-CELLS 1 MELANOMA ANTIGEN RECOGNIZED BY T-CELLS 1 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;melanosome#GO:0042470;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000010201.4|UniProtKB=F6SBN2 F6SBN2 ZNF385B PTHR23067:SF8 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385B nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000008084.3|UniProtKB=F6Y1S9 F6Y1S9 CCDC87 PTHR16078:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 87 COILED-COIL DOMAIN-CONTAINING PROTEIN 87 MONDO|Ensembl=ENSMODG00000010687.4|UniProtKB=F7C0S0 F7C0S0 CALCRL PTHR45620:SF21 PDF RECEPTOR-LIKE PROTEIN-RELATED CALCITONIN GENE-RELATED PEPTIDE TYPE 1 RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;cell communication#GO:0007154;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;system development#GO:0048731;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;response to stimulus#GO:0050896;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;developmental process#GO:0032502;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019693.3|UniProtKB=F6TCK3 F6TCK3 PTHR48001:SF146 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000043704.1|UniProtKB=A0A5F8G4M0 A0A5F8G4M0 ITGB3BP PTHR15581:SF0 CENTROMERE PROTEIN R CENTROMERE PROTEIN R intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000018808.4|UniProtKB=F6Z040 F6Z040 CILK1 PTHR24055:SF260 MITOGEN-ACTIVATED PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE ICK catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;organelle assembly#GO:0070925;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;localization#GO:0051179;cellular response to stimulus#GO:0051716;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;signal transduction#GO:0007165;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component assembly#GO:0022607;microtubule-based transport#GO:0099111;cilium organization#GO:0044782;cellular localization#GO:0051641;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cilium assembly#GO:0060271;signaling#GO:0023052;cell projection organization#GO:0030030;response to stimulus#GO:0050896 cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000045767.1|UniProtKB=A0A5F8GC68 A0A5F8GC68 CTTN PTHR10829:SF15 CORTACTIN AND DREBRIN SRC SUBSTRATE CORTACTIN cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 regulation of anatomical structure size#GO:0090066;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;nervous system development#GO:0007399;regulation of actin cytoskeleton organization#GO:0032956;animal gross anatomical part developmental process#GO:0160108;regulation of actin filament length#GO:0030832;cell-matrix adhesion#GO:0007160;generation of neurons#GO:0048699;cell adhesion#GO:0007155;regulation of biological quality#GO:0065008;neuron development#GO:0048666;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular component size#GO:0032535;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament-based process#GO:0032970;focal adhesion assembly#GO:0048041;neuron projection morphogenesis#GO:0048812;cell-substrate junction organization#GO:0150115;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of actin filament organization#GO:0110053;cell migration#GO:0016477;multicellular organismal process#GO:0032501;regulation of actin filament polymerization#GO:0030833;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;synapse organization#GO:0050808;anatomical structure development#GO:0048856;cell-substrate adhesion#GO:0031589;system development#GO:0048731;cell-substrate junction assembly#GO:0007044;regulation of supramolecular fiber organization#GO:1902903;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271 cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin filament#GO:0005884;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;lamellipodium#GO:0030027;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;glutamatergic synapse#GO:0098978;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;supramolecular fiber#GO:0099512;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000007229.4|UniProtKB=A0A5F8HKX2 A0A5F8HKX2 CILP2 PTHR15031:SF0 CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP CARTILAGE INTERMEDIATE LAYER PROTEIN 2 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000046322.1|UniProtKB=F7G7H5 F7G7H5 PTHR24028:SF234 CADHERIN-87A PROTOCADHERIN GAMMA-A7 cell adhesion#GO:0007155;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000003381.4|UniProtKB=F6ZP40 F6ZP40 SKOR2 PTHR10005:SF7 SKI ONCOGENE-RELATED SKI FAMILY TRANSCRIPTIONAL COREPRESSOR 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 negative regulation of BMP signaling pathway#GO:0030514;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;negative regulation of macromolecule metabolic process#GO:0010605;regulation of BMP signaling pathway#GO:0030510;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of signal transduction#GO:0009968;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000010213.3|UniProtKB=F6SAE1 F6SAE1 PTHR11630:SF66 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM4 isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676 DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;double-strand break repair via break-induced replication#GO:0000727;response to stress#GO:0006950;double-strand break repair#GO:0006302;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA replication initiation#GO:0006270;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;mitotic DNA replication#GO:1902969;nuclear DNA replication#GO:0033260;DNA repair#GO:0006281;cell cycle DNA replication#GO:0044786;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;MCM complex#GO:0042555 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000001009.3|UniProtKB=F6ZFK9 F6ZFK9 MYOG PTHR11534:SF5 MYOGENIC FACTOR MYOGENIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 animal organ development#GO:0048513;positive regulation of cell differentiation#GO:0045597;striated muscle tissue development#GO:0014706;positive regulation of transcription by RNA polymerase II#GO:0045944;muscle organ development#GO:0007517;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;tissue development#GO:0009888;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell development#GO:0060284;skeletal muscle tissue development#GO:0007519;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;muscle tissue development#GO:0060537;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000000392.2|UniProtKB=F6R7W3 F6R7W3 HAAO PTHR15497:SF1 3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE 3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000019554.4|UniProtKB=F6UTH0 F6UTH0 FKBP1A PTHR10516:SF301 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1A-RELATED catalytic activity, acting on a protein#GO:0140096;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;catalytic activity#GO:0003824 cell communication#GO:0007154;protein metabolic process#GO:0019538;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;regulation of transmembrane transport#GO:0034762;cellular response to stimulus#GO:0051716;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;regulation of heart contraction#GO:0008016;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of system process#GO:0044057;macromolecule metabolic process#GO:0043170;calcium-mediated signaling#GO:0019722;macromolecule biosynthetic process#GO:0009059;regulation of monoatomic ion transport#GO:0043269;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of muscle contraction#GO:0006937;regulation of muscle system process#GO:0090257;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;protein folding#GO:0006457;metabolic process#GO:0008152;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of release of sequestered calcium ion into cytosol#GO:0051279;signal transduction#GO:0007165;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;regulation of multicellular organismal process#GO:0051239;intracellular signaling cassette#GO:0141124 sarcoplasm#GO:0016528;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;sarcoplasmic reticulum#GO:0016529;sarcoplasmic reticulum membrane#GO:0033017;endomembrane system#GO:0012505;cytoplasm#GO:0005737 chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 MONDO|Ensembl=ENSMODG00000025138.3|UniProtKB=A0A5F8H5G4 A0A5F8H5G4 ADH5 PTHR43880:SF4 ALCOHOL DEHYDROGENASE ALCOHOL DEHYDROGENASE CLASS-3 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;zinc ion binding#GO:0008270;catalytic activity#GO:0003824;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;transition metal ion binding#GO:0046914;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;metal ion binding#GO:0046872 small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to toxic substance#GO:0009636;small molecule catabolic process#GO:0044282;cellular detoxification of aldehyde#GO:0110095;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;response to chemical#GO:0042221;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;aldehyde catabolic process#GO:0046185;cellular response to oxygen-containing compound#GO:1901701;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;metabolic process#GO:0008152 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000017554.4|UniProtKB=F7E0W0 F7E0W0 PTP4A2 PTHR23339:SF65 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE TYPE IVA 2 phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000043711.1|UniProtKB=A0A5F8GYN3 A0A5F8GYN3 PTHR14938:SF2 HCLS1-ASSOCIATED PROTEIN X-1 HCLS1-ASSOCIATED PROTEIN X-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 regulation of actin filament-based process#GO:0032970;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;cellular response to stimulus#GO:0051716;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;signal transduction#GO:0007165;response to peptide#GO:1901652;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of cellular component size#GO:0032535 mitochondrion#GO:0005739;vesicle#GO:0031982;intracellular vesicle#GO:0097708;actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;sarcoplasm#GO:0016528;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;sarcoplasmic reticulum#GO:0016529;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;apical part of cell#GO:0045177;endoplasmic reticulum#GO:0005783;cytoskeleton#GO:0005856;clathrin-coated vesicle#GO:0030136;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000009640.4|UniProtKB=A0A5F8GKZ2 A0A5F8GKZ2 ATRNL1 PTHR23244:SF467 KELCH REPEAT DOMAIN EF-HAND DOMAIN-CONTAINING PROTEIN signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 MONDO|Ensembl=ENSMODG00000003344.4|UniProtKB=A0A5F8GXD9 A0A5F8GXD9 KCNK10 PTHR11003:SF32 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 10 channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215 monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000010684.3|UniProtKB=F7C147 F7C147 DIAPH1 PTHR45691:SF4 PROTEIN DIAPHANOUS PROTEIN DIAPHANOUS HOMOLOG 1 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;actin cytoskeleton organization#GO:0030036;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 actin cytoskeleton#GO:0015629;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>mDia#P00510 MONDO|Ensembl=ENSMODG00000003296.3|UniProtKB=F7EFZ7 F7EFZ7 TM9SF1 PTHR10766:SF177 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 1 cellular process#GO:0009987;localization within membrane#GO:0051668;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000049183.1|UniProtKB=A0A5F8H5L9 A0A5F8H5L9 PTHR10177:SF444 CYCLINS CYCLIN-A2 enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin A#P04666 MONDO|Ensembl=ENSMODG00000016715.4|UniProtKB=A0A5F8GYN9 A0A5F8GYN9 ADRM1 PTHR12225:SF0 ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN PROTEASOMAL UBIQUITIN RECEPTOR ADRM1 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;proteasome regulatory particle, lid subcomplex#GO:0008541 MONDO|Ensembl=ENSMODG00000005494.2|UniProtKB=A0A5F8HKJ0 A0A5F8HKJ0 POLR2E PTHR10535:SF0 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription by RNA polymerase I#GO:0006360;DNA-templated transcription elongation#GO:0006354 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;RNA polymerase I complex#GO:0005736;RNA polymerase III complex#GO:0005666;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 MONDO|Ensembl=ENSMODG00000051194.1|UniProtKB=A0A5F8GM82 A0A5F8GM82 PTHR26454:SF77 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006517.4|UniProtKB=A0A5F8GV44 A0A5F8GV44 PTHR10075:SF107 BASIGIN RELATED BASIGIN cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000005811.3|UniProtKB=F6XEC4 F6XEC4 SLC10A2 PTHR10361:SF19 SODIUM-BILE ACID COTRANSPORTER ILEAL SODIUM_BILE ACID COTRANSPORTER solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;bile acid transmembrane transporter activity#GO:0015125;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;bile acid and bile salt transport#GO:0015721;lipid localization#GO:0010876;lipid transport#GO:0006869;macromolecule localization#GO:0033036 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000019141.3|UniProtKB=F7ECH0 F7ECH0 RAD51D PTHR46457:SF1 DNA REPAIR PROTEIN RAD51 HOMOLOG 4 DNA REPAIR PROTEIN RAD51 HOMOLOG 4 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;four-way junction DNA binding#GO:0000400 cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;response to stimulus#GO:0050896;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA damage response#GO:0006974;DNA repair#GO:0006281;reproductive process#GO:0022414;homologous recombination#GO:0035825;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;telomere organization#GO:0032200;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;replication fork#GO:0005657;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000013297.4|UniProtKB=F7BYE8 F7BYE8 PTHR17469:SF14 SPERM SPECIFIC ANTIGEN 2-RELATED PROTEIN ITPRID1 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000018156.4|UniProtKB=F7CWQ1 F7CWQ1 PTPN6 PTHR46257:SF4 TYROSINE-PROTEIN PHOSPHATASE CORKSCREW TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;protein binding#GO:0005515;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 mitotic cell cycle#GO:0000278;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;developmental process#GO:0032502;cellular process#GO:0009987;cell cycle#GO:0007049 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Interferon-gamma signaling pathway#P00035>PTP#P00960;Angiogenesis#P00005>SHP2#P00181;FGF signaling pathway#P00021>SHP2#P00647;B cell activation#P00010>SHP-1#P00378 MONDO|Ensembl=ENSMODG00000000881.4|UniProtKB=F7A885 F7A885 FSD1 PTHR24099:SF4 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FIBRONECTIN TYPE III AND SPRY DOMAIN-CONTAINING PROTEIN 1 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 regulation of mitotic spindle organization#GO:0060236;regulation of microtubule-based process#GO:0032886;regulation of cell division#GO:0051302;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of spindle organization#GO:0090224;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789 microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000003919.4|UniProtKB=F6YTW9 F6YTW9 FERMT1 PTHR16160:SF12 FERMITIN 2-RELATED FERMITIN FAMILY HOMOLOG 1 signaling receptor binding#GO:0005102;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178 cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589 anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000000351.4|UniProtKB=F6RUD2 F6RUD2 CFAP221 PTHR46500:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 221 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 221 cilium organization#GO:0044782;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 membrane-bounded organelle#GO:0043227;9+2 motile cilium#GO:0097729;cilium#GO:0005929;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000044770.1|UniProtKB=A0A5F8G717 A0A5F8G717 PTHR11227:SF27 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 2 small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;protein-macromolecule adaptor activity#GO:0030674;ion binding#GO:0043167;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981 cellular component assembly#GO:0022607;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052;macroautophagy#GO:0016236;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;pexophagy#GO:0000425;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;vacuole organization#GO:0007033;localization#GO:0051179;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;phagophore assembly site#GO:0000407 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019390.4|UniProtKB=F6WCE2 F6WCE2 TMC3 PTHR23302:SF35 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 3 gated channel activity#GO:0022836;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000013275.4|UniProtKB=F7AAB2 F7AAB2 KRT24 PTHR23239:SF207 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 24 structural molecule activity#GO:0005198 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular process#GO:0009987;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;morphogenesis of an epithelium#GO:0002009 intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000011190.4|UniProtKB=F6ZAG0 F6ZAG0 PTHR23310:SF53 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4 binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289 small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000003076.4|UniProtKB=F6PLF5 F6PLF5 SIRT7 PTHR11085:SF1 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-7 histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;NAD-dependent protein lysine deacetylase activity#GO:0034979;catalytic activity#GO:0003824;transferase activity#GO:0016740;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407 response to stimulus#GO:0050896;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000015417.4|UniProtKB=F6T3D8 F6T3D8 PUM3 PTHR13389:SF0 PUMILIO HOMOLOG 3 PUMILIO HOMOLOG 3 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000017807.4|UniProtKB=F7CFE9 F7CFE9 DCBLD1 PTHR46806:SF1 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN DISCOIDIN, CUB AND LCCL DOMAIN-CONTAINING PROTEIN 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000025472.2|UniProtKB=F6RJE2 F6RJE2 DPH3 PTHR21454:SF31 DPH3 HOMOLOG-RELATED DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3 cation binding#GO:0043169;metal ion binding#GO:0046872;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification process#GO:0036211;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000009328.4|UniProtKB=F7FZS2 F7FZS2 CCAR2 PTHR14304:SF12 CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN CELL CYCLE AND APOPTOSIS REGULATOR PROTEIN 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000046458.1|UniProtKB=A0A5F8GZT5 A0A5F8GZT5 monDomV1R1256 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045279.1|UniProtKB=A0A5F8HCR2 A0A5F8HCR2 PRUNE1 PTHR12112:SF47 BNIP - RELATED EXOPOLYPHOSPHATASE PRUNE1 hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000047164.1|UniProtKB=A0A5F8H971 A0A5F8H971 PTHR11753:SF18 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-1 COMPLEX SUBUNIT SIGMA-3 vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000020889.3|UniProtKB=A0A5F8HDQ4 A0A5F8HDQ4 HSD17B10 PTHR43658:SF17 SHORT-CHAIN DEHYDROGENASE/REDUCTASE 3-HYDROXYACYL-COA DEHYDROGENASE TYPE-2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 steroid metabolic process#GO:0008202;biological regulation#GO:0065007;small molecule metabolic process#GO:0044281;hormone metabolic process#GO:0042445;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;estrogen metabolic process#GO:0008210;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000005903.3|UniProtKB=F6XD58 F6XD58 AGRP PTHR16551:SF4 AGOUTI RELATED AGOUTI-RELATED PROTEIN molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;neuropeptide hormone activity#GO:0005184;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;receptor ligand activity#GO:0048018 feeding behavior#GO:0007631;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000003449.4|UniProtKB=F6TCQ0 F6TCQ0 SCYL3 PTHR12984:SF15 SCY1-RELATED S/T PROTEIN KINASE-LIKE PROTEIN-ASSOCIATING WITH THE CARBOXYL-TERMINAL DOMAIN OF EZRIN non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000047161.1|UniProtKB=A0A5F8HJW1 A0A5F8HJW1 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000007554.5|UniProtKB=F7G0A5 F7G0A5 KCNAB3 PTHR43150:SF3 HYPERKINETIC, ISOFORM M VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-3 potassium channel regulator activity#GO:0015459;transmembrane transporter binding#GO:0044325;transporter regulator activity#GO:0141108;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;binding#GO:0005488;channel regulator activity#GO:0016247;protein binding#GO:0005515;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;ion channel regulator activity#GO:0099106;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of transport#GO:0051049;regulation of localization#GO:0032879 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000010134.4|UniProtKB=F6WN26 F6WN26 ZFPL1 PTHR12981:SF0 ZINC FINGER PROTEIN-LIKE 1 ZINC FINGER PROTEIN-LIKE 1 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000018782.4|UniProtKB=F7AD87 F7AD87 BMP5 PTHR11848:SF139 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 5 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125 regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;response to growth factor#GO:0070848;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;multicellular organismal process#GO:0032501;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;multicellular organism development#GO:0007275;animal organ development#GO:0048513 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000011070.3|UniProtKB=O62738 O62738 RPS4X PTHR11581:SF0 30S/40S RIBOSOMAL PROTEIN S4 RIBOSOMAL PROTEIN S4 Y1-RELATED structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000016779.4|UniProtKB=F7G6J7 F7G6J7 PRCC PTHR13621:SF2 PROLINE-RICH PROTEIN PRCC PROLINE-RICH PROTEIN PRCC intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000015216.4|UniProtKB=A0A5F8GG15 A0A5F8GG15 STRADB PTHR48014:SF13 SERINE/THREONINE-PROTEIN KINASE FRAY2 STE20-RELATED KINASE ADAPTER PROTEIN BETA enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295 cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;protein export from nucleus#GO:0006611;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000025021.1|UniProtKB=F6X454 F6X454 LOC100028998 PTHR31551:SF1 PRE-MRNA-SPLICING FACTOR CWF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 12 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000008482.4|UniProtKB=F7G4C7 F7G4C7 MIPEP PTHR11804:SF79 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED MITOCHONDRIAL INTERMEDIATE PEPTIDASE metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000015513.3|UniProtKB=F6VYQ3 F6VYQ3 PTHR10183:SF302 CALPAIN CALPAIN-14 cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000046328.1|UniProtKB=K7E661 K7E661 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000004709.3|UniProtKB=F7FKY8 F7FKY8 DGAT2L6 PTHR12317:SF19 DIACYLGLYCEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 2-LIKE PROTEIN 6 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid biosynthetic process#GO:0008610;triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;neutral lipid metabolic process#GO:0006638;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 acyltransferase#PC00042;transferase#PC00220 MONDO|Ensembl=ENSMODG00000016316.4|UniProtKB=F7A5J6 F7A5J6 PTHR22912:SF151 DISULFIDE OXIDOREDUCTASE DIHYDROLIPOYL DEHYDROGENASE, MITOCHONDRIAL ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166 cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000038661.1|UniProtKB=A0A5F8GDU0 A0A5F8GDU0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010587.4|UniProtKB=F7GHS5 F7GHS5 AKAP9 PTHR44981:SF1 PERICENTRIN-LIKE PROTEIN, ISOFORM F A-KINASE ANCHOR PROTEIN 9 molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;protein kinase A binding#GO:0051018;channel regulator activity#GO:0016247;protein binding#GO:0005515;potassium channel regulator activity#GO:0015459;protein kinase A regulatory subunit binding#GO:0034237;transporter regulator activity#GO:0141108;binding#GO:0005488 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;centrosome localization#GO:0051642;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;organelle localization#GO:0051640 intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi stack#GO:0005795;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;synaptic membrane#GO:0097060;Golgi apparatus#GO:0005794;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;cis-Golgi network#GO:0005801;cell junction#GO:0030054;membraneless organelle#GO:0043228;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000002966.4|UniProtKB=F6Q5D3 F6Q5D3 HNF1A PTHR11568:SF4 HEPATOCYTE NUCLEAR FACTOR 1 HEPATOCYTE NUCLEAR FACTOR 1-ALPHA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000049591.1|UniProtKB=A0A5F8HK39 A0A5F8HK39 CCDC69 PTHR24200:SF6 TOUCAN, ISOFORM A COILED-COIL DOMAIN-CONTAINING PROTEIN 69 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000018306.4|UniProtKB=F6PVH5 F6PVH5 KPNA1 PTHR23316:SF3 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-5 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;cell communication#GO:0007154;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;signal transduction#GO:0007165;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 MONDO|Ensembl=ENSMODG00000011824.3|UniProtKB=F6YCS6 F6YCS6 LOC100010326 PTHR26453:SF148 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10A5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005643.4|UniProtKB=F7BW91 F7BW91 HTR4 PTHR24248:SF66 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 4 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000014448.3|UniProtKB=F7ATU3 F7ATU3 HSPB2 PTHR45640:SF27 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN BETA-2 protein folding#GO:0006457;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;protein refolding#GO:0042026;protein metabolic process#GO:0019538;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;response to heat#GO:0009408;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 chaperone#PC00072 VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 MONDO|Ensembl=ENSMODG00000007576.4|UniProtKB=F7CPW4 F7CPW4 MRPL48 PTHR13473:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L48 LARGE RIBOSOMAL SUBUNIT PROTEIN ML48 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000029086.2|UniProtKB=K7E4F5 K7E4F5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000046554.1|UniProtKB=A0A5F8G5X0 A0A5F8G5X0 PTHR45633:SF56 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 positive regulation of lymphocyte activation#GO:0051251;cellular response to topologically incorrect protein#GO:0035967;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;positive regulation of type I interferon production#GO:0032481;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;transport#GO:0006810;intracellular transport#GO:0046907;biosynthetic process#GO:0009058;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular localization#GO:0051641;immune system process#GO:0002376;response to topologically incorrect protein#GO:0035966;protein folding#GO:0006457;response to stimulus#GO:0050896;mitochondrial transport#GO:0006839;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;positive regulation of multicellular organismal process#GO:0051240;cellular component organization or biogenesis#GO:0071840;lymphocyte activation#GO:0046649;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;protein maturation#GO:0051604;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;positive regulation of immune system process#GO:0002684;localization#GO:0051179;positive regulation of biosynthetic process#GO:0009891;protein metabolic process#GO:0019538;cell activation#GO:0001775;cellular response to unfolded protein#GO:0034620;positive regulation of cytokine production#GO:0001819;cell death#GO:0008219;positive regulation of cell adhesion#GO:0045785;leukocyte activation#GO:0045321;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;establishment of localization#GO:0051234;regulation of leukocyte cell-cell adhesion#GO:1903037;mitochondrial protein import pathway#GO:7770058;regulation of macromolecule biosynthetic process#GO:0010556;response to unfolded protein#GO:0006986;positive regulation of metabolic process#GO:0009893;cellular response to stress#GO:0033554;regulation of lymphocyte activation#GO:0051249;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;T cell activation#GO:0042110;positive regulation of leukocyte activation#GO:0002696;metabolic process#GO:0008152;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;regulation of multicellular organismal process#GO:0051239;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;positive regulation of cell-cell adhesion#GO:0022409;response to stress#GO:0006950 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000016100.3|UniProtKB=F7EB35 F7EB35 RPL3L PTHR11363:SF7 60S RIBOSOMAL PROTEIN L3-RELATED RIBOSOMAL PROTEIN UL3-LIKE binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000041719.1|UniProtKB=A0A5F8G751 A0A5F8G751 PTHR13318:SF275 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX AND LEUCINE-RICH REPEAT PROTEIN 13 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;metabolic process#GO:0008152 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;catalytic complex#GO:1902494;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000040252.1|UniProtKB=A0A5F8GCR0 A0A5F8GCR0 EXOSC8 PTHR11097:SF9 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP43 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 nuclear mRNA surveillance#GO:0071028;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of gene expression#GO:0010468;snRNA processing#GO:0016180;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;snRNA metabolic process#GO:0016073;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular component biogenesis#GO:0044085;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;snRNA 3'-end processing#GO:0034472;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;maturation of 5.8S rRNA#GO:0000460;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 exoribonuclease#PC00099;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000001105.3|UniProtKB=F7DPK0 F7DPK0 PRELP PTHR45712:SF8 AGAP008170-PA PROLARGIN binding#GO:0005488;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367;heparin binding#GO:0008201 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000047876.1|UniProtKB=A0A5F8GW96 A0A5F8GW96 PTHR23169:SF7 ENVOPLAKIN ENVOPLAKIN organelle organization#GO:0006996;cellular component organization#GO:0016043;response to wounding#GO:0009611;response to stress#GO:0006950;cellular process#GO:0009987;response to stimulus#GO:0050896;intermediate filament cytoskeleton organization#GO:0045104;cytoskeleton organization#GO:0007010;intermediate filament-based process#GO:0045103;cellular component organization or biogenesis#GO:0071840;wound healing#GO:0042060 membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 intermediate filament#PC00129;intermediate filament binding protein#PC00130 MONDO|Ensembl=ENSMODG00000014047.3|UniProtKB=F6UPL0 F6UPL0 KIFC3 PTHR47972:SF5 KINESIN-LIKE PROTEIN KLP-3 KINESIN-LIKE PROTEIN KIFC3 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 microtubule-based process#GO:0007017;cellular process#GO:0009987 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000014223.2|UniProtKB=F6T9J4 F6T9J4 PTHR24072:SF136 RHO FAMILY GTPASE CELL DIVISION CONTROL PROTEIN 42 HOMOLOG guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 transport#GO:0006810;regulation of cell projection organization#GO:0031344;regulation of filopodium assembly#GO:0051489;actin filament organization#GO:0007015;establishment of localization#GO:0051234;import into cell#GO:0098657;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;regulation of cell projection assembly#GO:0060491;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;localization#GO:0051179;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of plasma membrane bounded cell projection assembly#GO:0120032 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein#PC00020;small GTPase#PC00208 Integrin signalling pathway#P00034>Cdc42#P00938;Gonadotropin-releasing hormone receptor pathway#P06664>Cdc42#P06743;CCKR signaling map#P06959>CDC42-GDP#P07044;Ras Pathway#P04393>Cdc42#P04569;Cytoskeletal regulation by Rho GTPase#P00016>Cdc42#P00515;CCKR signaling map#P06959>CDC42-GTP#P07155;T cell activation#P00053>cdc42#P01333;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Huntington disease#P00029>Rac#P00775;Axon guidance mediated by Slit/Robo#P00008>Cdc42#P00349;p38 MAPK pathway#P05918>Cdc42#P06041;Axon guidance mediated by netrin#P00009>cdc42#P00364 MONDO|Ensembl=ENSMODG00000040383.1|UniProtKB=A0A5F8HLQ7 A0A5F8HLQ7 SELENOH PTHR33638:SF1 SELENOPROTEIN H SELENOPROTEIN H cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000009587.3|UniProtKB=F7AW92 F7AW92 FABP1 PTHR11955:SF96 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, LIVER fatty acid binding#GO:0005504;lipid binding#GO:0008289;ion binding#GO:0043167;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;organic acid binding#GO:0043177 establishment of localization#GO:0051234;fatty acid transport#GO:0015908;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;lipid transport#GO:0006869;macromolecule localization#GO:0033036 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000014353.4|UniProtKB=A0A5F8GBZ8 A0A5F8GBZ8 PPIL2 PTHR45625:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED RING-TYPE E3 UBIQUITIN-PROTEIN LIGASE PPIL2 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;cis-trans isomerase activity#GO:0016859;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000023728.2|UniProtKB=F6TXR1 F6TXR1 GTF2H3 PTHR12831:SF0 TRANSCRIPTION INITIATION FACTOR IIH TFIIH , POLYPEPTIDE 3-RELATED GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 3 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;response to stimulus#GO:0050896;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;transcription regulator complex#GO:0005667;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;transcription factor TFIIH core complex#GO:0000439;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription factor TFIIH holo complex#GO:0005675 RNA metabolism protein#PC00031;general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392;General transcription regulation#P00023>TFIIH complex#P00664 MONDO|Ensembl=ENSMODG00000012885.3|UniProtKB=A0A5F8GS72 A0A5F8GS72 PTHR11910:SF1 ATP SYNTHASE DELTA CHAIN ATP SYNTHASE PERIPHERAL STALK SUBUNIT OSCP, MITOCHONDRIAL proton channel activity#GO:0015252;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;channel activity#GO:0015267 nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;ATP biosynthetic process#GO:0006754;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;phosphorus metabolic process#GO:0006793;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;aerobic respiration#GO:0009060;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227;ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000017346.4|UniProtKB=F6WFF7 F6WFF7 CTPS1 PTHR11550:SF8 CTP SYNTHASE CTP SYNTHASE 1 identical protein binding#GO:0042802;ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515;ligase activity#GO:0016874;binding#GO:0005488;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;ribose phosphate biosynthetic process#GO:0046390;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;pyrimidine nucleobase metabolic process#GO:0006206;ribonucleoside triphosphate biosynthetic process#GO:0009201 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080 ligase#PC00142;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>CTP synthase#P02931 MONDO|Ensembl=ENSMODG00000014424.4|UniProtKB=F7BGK1 F7BGK1 MRPS35 PTHR13490:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN MS35 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000019494.4|UniProtKB=F6VUX5 F6VUX5 MTREX PTHR12131:SF7 ATP-DEPENDENT RNA AND DNA HELICASE EXOSOME RNA HELICASE MTR4 helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657 nucleobase-containing compound catabolic process#GO:0034655;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule catabolic process#GO:0009057;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000017315.4|UniProtKB=F6XCL7 F6XCL7 RIMKLA PTHR21621:SF1 RIBOSOMAL PROTEIN S6 MODIFICATION PROTEIN N-ACETYLASPARTYLGLUTAMATE SYNTHASE A ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000039656.1|UniProtKB=A0A5F8GSU4 A0A5F8GSU4 PTHR16515:SF79 PR DOMAIN ZINC FINGER PROTEIN ZINC FINGER PROTEIN 883-LIKE regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000003111.4|UniProtKB=F6S3G1 F6S3G1 RNF10 PTHR12983:SF10 RING FINGER 10 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RNF10 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;regulation of system process#GO:0044057;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;regulation of multicellular organismal process#GO:0051239;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;protein metabolic process#GO:0019538;regulation of nervous system development#GO:0051960;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000013999.4|UniProtKB=F7C2Z8 F7C2Z8 MAN1C1 PTHR11742:SF28 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IC hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000023552.2|UniProtKB=F7BQV5 F7BQV5 ZBTB26 PTHR24399:SF14 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 26 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110 negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000000837.3|UniProtKB=A0A5F8H8V0 A0A5F8H8V0 TXN2 PTHR43601:SF39 THIOREDOXIN, MITOCHONDRIAL THIOREDOXIN, MITOCHONDRIAL cellular homeostasis#GO:0019725;homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 MONDO|Ensembl=ENSMODG00000041059.1|UniProtKB=A0A5F8G3Y5 A0A5F8G3Y5 PTHR15484:SF8 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA34 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA34 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase I complex#GO:0005736 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000021267.4|UniProtKB=F6T2Y0 F6T2Y0 COMMD2 PTHR15857:SF0 COMM DOMAIN CONTAINING PROTEIN 2 COMM DOMAIN-CONTAINING PROTEIN 2 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000000542.4|UniProtKB=A0A5F8HEB4 A0A5F8HEB4 PTHR11941:SF44 ENOYL-COA HYDRATASE-RELATED ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 2, MITOCHONDRIAL hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 hydratase#PC00120;lyase#PC00144;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000020825.4|UniProtKB=F6RM18 F6RM18 LOC100028548 PTHR12035:SF125 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 5 organic acid binding#GO:0043177;ion binding#GO:0043167;carbohydrate derivative binding#GO:0097367;binding#GO:0005488;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;anion binding#GO:0043168 cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000040115.1|UniProtKB=F7BX10 F7BX10 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008649.3|UniProtKB=F6PGB4 F6PGB4 PTHR10344:SF9 THYMIDYLATE KINASE THYMIDYLATE KINASE phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleoside diphosphate metabolic process#GO:0009132 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;nucleotide kinase#PC00172;kinase#PC00137 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTMP kinase#P02916 MONDO|Ensembl=ENSMODG00000000964.5|UniProtKB=F7ESY3 F7ESY3 TBC1D4 PTHR22957:SF195 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 4 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000000348.4|UniProtKB=F6RUI0 F6RUI0 DENND2C PTHR15288:SF6 DENN DOMAIN-CONTAINING PROTEIN 2 DENN DOMAIN-CONTAINING PROTEIN 2C molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000005442.2|UniProtKB=F7D0J2 F7D0J2 PTHR24250:SF66 CHYMOTRYPSIN-RELATED CHYMOTRYPSIN-LIKE PROTEASE CTRL-1 catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein modifying enzyme#PC00260;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000002734.4|UniProtKB=A0A5F8HB11 A0A5F8HB11 USP34 PTHR24006:SF827 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 34 cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000023350.2|UniProtKB=F6TSC0 F6TSC0 PTHR23121:SF9 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SOLUTE CARRIER FAMILY 60 MEMBER 2 transporter#PC00227 MONDO|Ensembl=ENSMODG00000007351.2|UniProtKB=F7B0E1 F7B0E1 LOC100029283 PTHR24242:SF183 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11G2 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000006818.4|UniProtKB=A0A5F8HDM6 A0A5F8HDM6 GPRC5C PTHR14511:SF15 G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5 G PROTEIN-COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER C kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887 vesicle#GO:0031982;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000004497.4|UniProtKB=A0A5F8HC77 A0A5F8HC77 ABCD3 PTHR11384:SF62 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 3 carboxylic acid transmembrane transporter activity#GO:0046943;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;monocarboxylic acid transmembrane transporter activity#GO:0008028;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076 organelle organization#GO:0006996;lipid catabolic process#GO:0016042;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;metabolic process#GO:0008152;fatty acid oxidation#GO:0019395;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;cellular component organization or biogenesis#GO:0071840;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;cellular component organization#GO:0016043;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;small molecule catabolic process#GO:0044282;lipid localization#GO:0010876;oxoacid metabolic process#GO:0043436;peroxisome organization#GO:0007031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;fatty acid catabolic process#GO:0009062;macromolecule localization#GO:0033036;carboxylic acid catabolic process#GO:0046395;lipid transport#GO:0006869;monocarboxylic acid catabolic process#GO:0072329;intracellular transport#GO:0046907;fatty acid metabolic process#GO:0006631;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;transport#GO:0006810;lipid modification#GO:0030258;establishment of localization#GO:0051234;primary metabolic process#GO:0044238;catabolic process#GO:0009056;carboxylic acid transmembrane transport#GO:1905039;fatty acid transport#GO:0015908;localization#GO:0051179;lipid oxidation#GO:0034440;monocarboxylic acid transport#GO:0015718;peroxisomal transport#GO:0043574 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579 primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000027407.2|UniProtKB=K7DYW3 K7DYW3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000019919.5|UniProtKB=F6VP12 F6VP12 MTCH2 PTHR10780:SF20 MITOCHONDRIAL CARRIER HOMOLOG MITOCHONDRIAL CARRIER HOMOLOG 2 membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 regulation of apoptotic process#GO:0042981;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;positive regulation of apoptotic process#GO:0043065;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;positive regulation of cellular process#GO:0048522;establishment of protein localization#GO:0045184;mitochondrial membrane organization#GO:0007006;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;localization within membrane#GO:0051668;protein insertion into mitochondrial outer membrane#GO:0045040;localization#GO:0051179;cellular localization#GO:0051641;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein localization to mitochondrion#GO:0070585;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;positive regulation of programmed cell death#GO:0043068 mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000017641.4|UniProtKB=F6Z4J1 F6Z4J1 SNAP29 PTHR19305:SF42 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 29 protein binding#GO:0005515;SNAP receptor activity#GO:0005484;syntaxin binding#GO:0019905;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488 localization#GO:0051179;secretion#GO:0046903;secretion by cell#GO:0032940;cellular component organization#GO:0016043;export from cell#GO:0140352;vesicle fusion#GO:0006906;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;exocytosis#GO:0006887;vesicle organization#GO:0016050;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular process#GO:0009987;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174 cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;plasma membrane#GO:0005886;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049 MONDO|Ensembl=ENSMODG00000004548.4|UniProtKB=F6R5H6 F6R5H6 FKBP15 PTHR44927:SF1 FK506-BINDING PROTEIN 15 FK506-BINDING PROTEIN 15 neuron projection#GO:0043005;cell projection#GO:0042995;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;axon#GO:0030424;growth cone#GO:0030426;site of polarized growth#GO:0030427 MONDO|Ensembl=ENSMODG00000017875.4|UniProtKB=K7E4J1 K7E4J1 PTHR47117:SF13 STAR-RELATED LIPID TRANSFER PROTEIN 9 STAR-RELATED LIPID TRANSFER PROTEIN 9 MONDO|Ensembl=ENSMODG00000036569.1|UniProtKB=A0A5F8G7B9 A0A5F8G7B9 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000039608.1|UniProtKB=A0A5F8GYP1 A0A5F8GYP1 CANT1 PTHR13023:SF3 APYRASE SOLUBLE CALCIUM-ACTIVATED NUCLEOTIDASE 1 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058 membrane#GO:0016020;cellular anatomical structure#GO:0110165 nucleotide phosphatase#PC00173;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000006814.4|UniProtKB=F6PGJ9 F6PGJ9 SERPINH1 PTHR11461:SF27 SERINE PROTEASE INHIBITOR, SERPIN SERPIN H1 peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000011251.3|UniProtKB=F6RLS7 F6RLS7 VAX2 PTHR24339:SF34 HOMEOBOX PROTEIN EMX-RELATED VENTRAL ANTERIOR HOMEOBOX 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;animal organ development#GO:0048513;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;head development#GO:0060322;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000015829.4|UniProtKB=A0A5F8H5N3 A0A5F8H5N3 CCHCR1 PTHR46822:SF1 COILED-COIL ALPHA-HELICAL ROD PROTEIN 1 COILED-COIL ALPHA-HELICAL ROD PROTEIN 1 intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;protein export from nucleus#GO:0006611;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;nuclear transport#GO:0051169;nuclear export#GO:0051168;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000024904.2|UniProtKB=F6WSF7 F6WSF7 PTHR15641:SF1 ELONGATOR COMPLEX PROTEIN 5 ELONGATOR COMPLEX PROTEIN 5 nucleic acid binding#GO:0003676;binding#GO:0005488;tRNA binding#GO:0000049;RNA binding#GO:0003723 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;elongator holoenzyme complex#GO:0033588;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000003358.4|UniProtKB=F6ZPW2 F6ZPW2 KATNAL2 PTHR23074:SF78 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 2 ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cellular process#GO:0009987;cell cycle process#GO:0022402;cytoskeleton organization#GO:0007010;reproductive process#GO:0022414;meiotic cell cycle#GO:0051321;sexual reproduction#GO:0019953;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000037887.1|UniProtKB=A0A5F8GHE8 A0A5F8GHE8 PTHR12448:SF0 ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL ATP SYNTHASE F(1) COMPLEX SUBUNIT EPSILON, MITOCHONDRIAL monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252 nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;proton motive force-driven ATP synthesis#GO:0015986;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000003301.4|UniProtKB=F7EFQ7 F7EFQ7 ARHGEF19 PTHR12845:SF6 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 19 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 response to stress#GO:0006950;response to wounding#GO:0009611;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cytoskeleton organization#GO:0051493;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;wound healing#GO:0042060 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000005699.4|UniProtKB=F6UK12 F6UK12 KCNH7 PTHR10217:SF466 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED INWARDLY RECTIFYING POTASSIUM CHANNEL KCNH7 gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000025295.2|UniProtKB=F7A2C6 F7A2C6 MID1IP1 PTHR14315:SF16 SPOT14 FAMILY MEMBER MID1-INTERACTING PROTEIN 1 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of lipid biosynthetic process#GO:0046890;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;regulation of lipid metabolic process#GO:0019216 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000019718.3|UniProtKB=F6XMD5 F6XMD5 LOC100017590 PTHR26452:SF119 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5C1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000001973.4|UniProtKB=F6RIP7 F6RIP7 RXFP1 PTHR24372:SF68 GLYCOPROTEIN HORMONE RECEPTOR RELAXIN RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000001646.4|UniProtKB=A0A5F8H5U8 A0A5F8H5U8 CRPPA PTHR43015:SF1 D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220 MONDO|Ensembl=ENSMODG00000006218.4|UniProtKB=F7BLY3 F7BLY3 PTHR26453:SF685 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019353.4|UniProtKB=F6X9M8 F6X9M8 PAX2 PTHR45636:SF19 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000009422.4|UniProtKB=F7BLH3 F7BLH3 C7orf57 PTHR31097:SF2 SI:DKEY-276J7.1 CHROMOSOME 7 OPEN READING FRAME 57 MONDO|Ensembl=ENSMODG00000012737.3|UniProtKB=F6TGU8 F6TGU8 FBXL20 PTHR13382:SF67 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B F-BOX AND LEUCINE RICH REPEAT PROTEIN 20 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000000929.4|UniProtKB=F7F824 F7F824 SLC16A1 PTHR11360:SF24 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;proton transmembrane transporter activity#GO:0015078;monocarboxylic acid transmembrane transporter activity#GO:0008028;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000013475.4|UniProtKB=F7FMJ6 F7FMJ6 UQCRC1 PTHR11851:SF116 METALLOPROTEASE CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585;localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104 endopeptidase complex#GO:1905369;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000024328.2|UniProtKB=F7DGB9 F7DGB9 LOC100023056 PTHR26452:SF828 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007176.4|UniProtKB=F6RC78 F6RC78 CHRDL2 PTHR46303:SF3 VWFC DOMAIN-CONTAINING PROTEIN CHORDIN-LIKE PROTEIN 2 cytokine binding#GO:0019955;protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of BMP signaling pathway#GO:0030514;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cell communication#GO:0010646;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000043705.1|UniProtKB=A0A5F8GRE5 A0A5F8GRE5 PTHR10681:SF182 THIOREDOXIN PEROXIDASE THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE, MITOCHONDRIAL oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601 hydrogen peroxide metabolic process#GO:0042743;homeostatic process#GO:0042592;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular process#GO:0009987;response to stress#GO:0006950;cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;response to oxidative stress#GO:0006979;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 peroxidase#PC00180;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000003997.4|UniProtKB=F7DS70 F7DS70 SUCO PTHR12953:SF10 MEMBRANE PROTEIN CH1 RELATED SUN DOMAIN-CONTAINING OSSIFICATION FACTOR biological regulation#GO:0065007;regulation of tissue remodeling#GO:0034103;regulation of multicellular organismal process#GO:0051239;regulation of biological process#GO:0050789;regulation of bone remodeling#GO:0046850 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000006163.3|UniProtKB=A0A5F8H4P8 A0A5F8H4P8 XRN2 PTHR12341:SF41 5'->3' EXORIBONUCLEASE 5'-3' EXORIBONUCLEASE 2 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;exonuclease activity#GO:0004527;nucleic acid binding#GO:0003676;binding#GO:0005488;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409 regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;exoribonuclease#PC00099 DNA replication#P00017>5' to 3' Exoribonulcease#P00535 MONDO|Ensembl=ENSMODG00000007703.4|UniProtKB=F7F9E8 F7F9E8 TMEM260 PTHR16214:SF3 TRANSMEMBRANE PROTEIN 260 PROTEIN O-MANNOSYL-TRANSFERASE TMEM260 MONDO|Ensembl=ENSMODG00000009778.5|UniProtKB=F6SZX9 F6SZX9 EIF3B PTHR14068:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 eukaryotic translation initiation factor 3 complex#GO:0005852;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000037190.1|UniProtKB=K7E5X6 K7E5X6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001166.3|UniProtKB=F6W006 F6W006 SPRED1 PTHR11202:SF18 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004622.4|UniProtKB=A0A5F8G9U0 A0A5F8G9U0 MARK1 PTHR24346:SF21 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE MARK1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000013492.4|UniProtKB=F6WK12 F6WK12 PSME3IP1 PTHR13495:SF0 NEFA-INTERACTING NUCLEAR PROTEIN NIP30 PSME3-INTERACTING PROTEIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000019587.5|UniProtKB=F6QM51 F6QM51 PTHR13374:SF3 DET1 HOMOLOG DE-ETIOLATED-1 HOMOLOG DET1 HOMOLOG binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin-like ligase-substrate adaptor activity#GO:1990756;ubiquitin-like protein ligase binding#GO:0044389;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin protein ligase binding#GO:0031625 positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;protein ubiquitination#GO:0016567;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;positive regulation of protein metabolic process#GO:0051247;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of metabolic process#GO:0009893 intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000008867.4|UniProtKB=F7CU18 F7CU18 EIF3F PTHR10540:SF6 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F translation factor activity#GO:0180051;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;translation initiation factor activity#GO:0003743;catalytic activity, acting on a protein#GO:0140096;translation initiation factor binding#GO:0031369;metallopeptidase activity#GO:0008237;deubiquitinase activity#GO:0101005;binding#GO:0005488;hydrolase activity#GO:0016787;protein binding#GO:0005515 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000028616.2|UniProtKB=K7E4A7 K7E4A7 PTHR14759:SF34 STOP PROTEIN MUCIN-LIKE DOMAIN-CONTAINING PROTEIN microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of microtubule-based process#GO:0032886;localization#GO:0051179;cellular localization#GO:0051641 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;cis-Golgi network#GO:0005801;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;supramolecular complex#GO:0099080 MONDO|Ensembl=ENSMODG00000003404.2|UniProtKB=F6Z0A4 F6Z0A4 PTHR18937:SF172 STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;nuclear division#GO:0000280 chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;condensin complex#GO:0000796;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000025521.3|UniProtKB=F6VJ03 F6VJ03 LOC100024418 PTHR28583:SF4 ACID AMIDASE N-ACYLETHANOLAMINE-HYDROLYZING ACID AMIDASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000006978.4|UniProtKB=A0A5F8H055 A0A5F8H055 PRDX2 PTHR10681:SF161 THIOREDOXIN PEROXIDASE PEROXIREDOXIN-2 peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 response to toxic substance#GO:0009636;response to stimulus#GO:0050896;catabolic process#GO:0009056;hydrogen peroxide metabolic process#GO:0042743;homeostatic process#GO:0042592;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular detoxification#GO:1990748;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;response to stress#GO:0006950;cellular process#GO:0009987;cellular oxidant detoxification#GO:0098869;cellular response to oxygen-containing compound#GO:1901701;cellular response to chemical stress#GO:0062197;superoxide metabolic process#GO:0006801;response to oxidative stress#GO:0006979;cellular homeostasis#GO:0019725;response to reactive oxygen species#GO:0000302;cell redox homeostasis#GO:0045454;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 oxidoreductase#PC00176;peroxidase#PC00180 MONDO|Ensembl=ENSMODG00000010751.4|UniProtKB=F7FWJ5 F7FWJ5 CRTC3 PTHR13589:SF4 CREB-REGULATED TRANSCRIPTION COACTIVATOR CREB-REGULATED TRANSCRIPTION COACTIVATOR 3 transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;binding#GO:0005488;transcription coregulator activity#GO:0003712;DNA-binding transcription factor binding#GO:0140297;transcription coactivator activity#GO:0003713;protein binding#GO:0005515 regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to nitrogen compound#GO:1901699;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;negative regulation of signal transduction#GO:0009968;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000025717.2|UniProtKB=F6T2R6 F6T2R6 PTHR10500:SF7 BETA-MICROSEMINOPROTEIN MICROSEMINOPROTEIN BETA intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000001253.4|UniProtKB=F7CJ73 F7CJ73 PTHR11660:SF50 SOLUTE CARRIER FAMILY 40 MEMBER FERROPORTIN ISOFORM X1 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000041754.1|UniProtKB=F7FUJ7 F7FUJ7 LOC100032661 PTHR12882:SF1 SUPPRESSOR OF TY 4 TRANSCRIPTION ELONGATION FACTOR SPT4 binding#GO:0005488;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000004147.4|UniProtKB=F6RA79 F6RA79 PRKCA PTHR24356:SF193 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C ALPHA TYPE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>PKCs#P00318;Alpha adrenergic receptor signaling pathway#P00002>PKC#P00075;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;CCKR signaling map#P06959>PKCalpha#P07095;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PKC#P05942;PDGF signaling pathway#P00047>PKC#P01150;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs(3)#P06850;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Angiogenesis#P00005>PKC#P00219;VEGF signaling pathway#P00056>PKC#P01425;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Endothelin signaling pathway#P00019>PKC#P00568 MONDO|Ensembl=ENSMODG00000016680.3|UniProtKB=A0A5F8G2L5 A0A5F8G2L5 DPYSL2 PTHR11647:SF56 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;dihydropyrimidinase activity#GO:0004157 cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;pyrimidine nucleobase catabolic process#GO:0006208;primary metabolic process#GO:0044238;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;metabolic process#GO:0008152;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;pyrimidine nucleobase metabolic process#GO:0006206 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 MONDO|Ensembl=ENSMODG00000000947.5|UniProtKB=F7F4V4 F7F4V4 FAM83G PTHR16181:SF39 PROTEIN FAM83A-RELATED PROTEIN FAM83G binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515 cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000000975.3|UniProtKB=F7ESF8 F7ESF8 KHDRBS3 PTHR11208:SF29 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 3 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000010181.4|UniProtKB=F6SUN5 F6SUN5 PGRMC1 PTHR10281:SF23 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT 1 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009466.4|UniProtKB=A0A5F8GPM3 A0A5F8GPM3 VANGL2 PTHR20886:SF10 VANG-LIKE PROTEIN VANG-LIKE PROTEIN 2 signaling#GO:0023052;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;non-canonical Wnt signaling pathway#GO:0035567;anatomical structure development#GO:0048856;cell communication#GO:0007154;tissue morphogenesis#GO:0048729;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;tissue development#GO:0009888;epithelium development#GO:0060429;cellular process#GO:0009987;signal transduction#GO:0007165;morphogenesis of an epithelium#GO:0002009;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000024861.3|UniProtKB=F7A982 F7A982 CFAP95 PTHR35069:SF1 PROTEIN C9ORF135 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 95 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000002230.4|UniProtKB=A0A5F8GCZ4 A0A5F8GCZ4 C4BPA PTHR19325:SF551 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING C4B-BINDING PROTEIN ALPHA CHAIN adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;T cell mediated immunity#GO:0002456;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 complement component#PC00078;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000007818.4|UniProtKB=F7ETR3 F7ETR3 ABCB11 PTHR24221:SF165 ATP-BINDING CASSETTE SUB-FAMILY B BILE SALT EXPORT PUMP active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000007480.3|UniProtKB=A0A5F8GDJ6 A0A5F8GDJ6 RPL27A PTHR11721:SF3 60S RIBOSOMAL PROTEIN L27A LARGE RIBOSOMAL SUBUNIT PROTEIN UL15 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000013717.3|UniProtKB=F6Y9A7 F6Y9A7 PSMC4 PTHR23073:SF155 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6B isomerase activity#GO:0016853;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 proteasome complex#GO:0000502;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protease#PC00190 Ubiquitin proteasome pathway#P00060>19S proteasome#P01494;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000029229.2|UniProtKB=K7DYW1 K7DYW1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000005914.4|UniProtKB=F6R2B1 F6R2B1 CFI PTHR24253:SF91 TRANSMEMBRANE PROTEASE SERINE COMPLEMENT FACTOR I catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000019005.4|UniProtKB=F7CP70 F7CP70 GTF2E2 PTHR12716:SF8 TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;transcription factor binding#GO:0008134;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIE#P00666;General transcription regulation#P00023>TFIIEbeta#P00659;Transcription regulation by bZIP transcription factor#P00055>TFIIEbeta#P01386;Transcription regulation by bZIP transcription factor#P00055>TFIIE#P01395 MONDO|Ensembl=ENSMODG00000043109.1|UniProtKB=A0A5F8G8G4 A0A5F8G8G4 PTHR11721:SF3 60S RIBOSOMAL PROTEIN L27A LARGE RIBOSOMAL SUBUNIT PROTEIN UL15 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000006341.3|UniProtKB=A0A5F8GFR6 A0A5F8GFR6 UBTD2 PTHR13609:SF20 UBIQUITIN DOMAIN CONTAINING 1 PROTEIN-RELATED UBIQUITIN DOMAIN-CONTAINING PROTEIN 2 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000005955.4|UniProtKB=F6WF95 F6WF95 LOC100025162 PTHR24376:SF85 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 600-RELATED negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000020166.2|UniProtKB=F6YRB1 F6YRB1 PTHR48018:SF131 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023465.3|UniProtKB=F7BP19 F7BP19 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000045706.1|UniProtKB=A0A5F8GP24 A0A5F8GP24 RPL39 PTHR19970:SF0 RIBOSOMAL PROTEIN L39E LARGE RIBOSOMAL SUBUNIT PROTEIN EL39 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000044320.1|UniProtKB=F6TBR5 F6TBR5 LOC100017340 PTHR26453:SF302 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018438.4|UniProtKB=F6XBQ2 F6XBQ2 TMEM121B PTHR47399:SF1 TRANSMEMBRANE PROTEIN 121B TRANSMEMBRANE PROTEIN 121B MONDO|Ensembl=ENSMODG00000012544.4|UniProtKB=F6PNM9 F6PNM9 BARHL1 PTHR24330:SF8 HOMEOBOX PROTEIN BARH-LIKE BARH-LIKE 1 HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000004455.4|UniProtKB=F6R7I1 F6R7I1 SLC26A1 PTHR11814:SF31 SULFATE TRANSPORTER SULFATE ANION TRANSPORTER 1 carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic ion transmembrane transporter activity#GO:0015075;dicarboxylic acid transmembrane transporter activity#GO:0005310;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000041990.1|UniProtKB=A0A5F8HHM7 A0A5F8HHM7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000011352.4|UniProtKB=F6W2L7 F6W2L7 SACM1L PTHR45662:SF2 PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 phosphatase#PC00181;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000015754.4|UniProtKB=F7AH12 F7AH12 CTTNBP2 PTHR24166:SF27 ROLLING PEBBLES, ISOFORM B CORTACTIN-BINDING PROTEIN 2 regulation of synapse organization#GO:0050807;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of synapse structure or activity#GO:0050803;regulation of cellular component organization#GO:0051128;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000012946.5|UniProtKB=F7G1J7 F7G1J7 BAZ1A PTHR46510:SF1 BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of DNA replication#GO:0045740;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;regulation of DNA replication#GO:0006275;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of chromatin organization#GO:1902275;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;positive regulation of DNA metabolic process#GO:0051054;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789 SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ISWI-type complex#GO:0031010;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000009516.4|UniProtKB=F6XH22 F6XH22 PTHR11289:SF0 BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2 BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 cellular process#GO:0009987;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;double-strand break repair#GO:0006302;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000046267.1|UniProtKB=A0A5F8GN39 A0A5F8GN39 PTHR14273:SF0 LYR MOTIF-CONTAINING PROTEIN 1 LYR MOTIF-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000028951.2|UniProtKB=K7E654 K7E654 SHB PTHR15127:SF31 HEAVYWEIGHT, ISOFORM A SH2 DOMAIN-CONTAINING ADAPTER PROTEIN B protein binding#GO:0005515;binding#GO:0005488 MONDO|Ensembl=ENSMODG00000020253.4|UniProtKB=F6ZI76 F6ZI76 XRCC4 PTHR28559:SF2 DNA REPAIR PROTEIN XRCC4 DNA REPAIR PROTEIN XRCC4 anatomical structure development#GO:0048856;system development#GO:0048731;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;somatic diversification of immune receptors#GO:0002200;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;DNA repair#GO:0006281;DNA damage response#GO:0006974;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;somatic cell DNA recombination#GO:0016444;response to radiation#GO:0009314;macromolecule biosynthetic process#GO:0009059;immune system development#GO:0002520;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;production of molecular mediator of immune response#GO:0002440;response to abiotic stimulus#GO:0009628;response to ionizing radiation#GO:0010212;V(D)J recombination#GO:0033151;multicellular organism development#GO:0007275;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;gene expression#GO:0010467;response to stress#GO:0006950;somatic recombination of immunoglobulin gene segments#GO:0016447;cellular process#GO:0009987 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;DNA repair complex#GO:1990391;intracellular membrane-bounded organelle#GO:0043231;nonhomologous end joining complex#GO:0070419;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000014886.2|UniProtKB=F7GGI4 F7GGI4 RNF5 PTHR12313:SF4 E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF5 cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;regulation of autophagosome assembly#GO:2000785;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;catabolic process#GO:0009056;response to stimulus#GO:0050896;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;regulation of organelle assembly#GO:1902115;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;response to chemical#GO:0042221 membrane#GO:0016020;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000015595.3|UniProtKB=F6ZUE1 F6ZUE1 ELMOD3 PTHR12771:SF2 ENGULFMENT AND CELL MOTILITY ELMO DOMAIN-CONTAINING PROTEIN 3 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 Golgi apparatus#GO:0005794;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017872.4|UniProtKB=A0A5F8GBX9 A0A5F8GBX9 PLEKHA5 PTHR12752:SF3 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 5 lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000004336.4|UniProtKB=F7B2P3 F7B2P3 UVSSA PTHR28670:SF1 UV-STIMULATED SCAFFOLD PROTEIN A UV-STIMULATED SCAFFOLD PROTEIN A enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515 cellular process#GO:0009987;response to radiation#GO:0009314;response to stress#GO:0006950;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;response to UV#GO:0009411;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to stress#GO:0033554 chromosome#GO:0005694;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000050823.1|UniProtKB=A0A5F8GT36 A0A5F8GT36 COA8 PTHR31107:SF2 APOPTOGENIC PROTEIN 1, MITOCHONDRIAL CYTOCHROME C OXIDASE ASSEMBLY FACTOR 8 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000028254.2|UniProtKB=K7E3H1 K7E3H1 PTHR12125:SF9 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 27 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000046159.1|UniProtKB=A0A5F8GFE2 A0A5F8GFE2 PTHR19134:SF297 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE H phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon development#GO:0061564;axon guidance#GO:0007411;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000008737.3|UniProtKB=F6PTF8 F6PTF8 PTHR26450:SF177 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52I1-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015142.4|UniProtKB=F7CZL9 F7CZL9 TRPC7 PTHR10117:SF9 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 7 transporter activity#GO:0005215;alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;channel activity#GO:0015267 sexual reproduction#GO:0019953;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;homeostatic process#GO:0042592;fertilization#GO:0009566;reproductive process#GO:0022414;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;single fertilization#GO:0007338;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 MONDO|Ensembl=ENSMODG00000049826.1|UniProtKB=F6PZ52 F6PZ52 LOC100017286 PTHR26450:SF77 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000041902.1|UniProtKB=A0A5F8GP20 A0A5F8GP20 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000018944.4|UniProtKB=F7GB10 F7GB10 MAD2L1 PTHR11842:SF11 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of chromosome organization#GO:2001251;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;cell communication#GO:0007154;regulation of mitotic cell cycle#GO:0007346;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;regulation of mitotic nuclear division#GO:0007088;negative regulation of chromosome separation#GO:1905819;regulation of mitotic sister chromatid separation#GO:0010965;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cellular process#GO:0009987;signal transduction#GO:0007165;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of sister chromatid segregation#GO:0033046;regulation of cell cycle process#GO:0010564;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of chromosome separation#GO:1905818;regulation of chromosome segregation#GO:0051983;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of chromosome segregation#GO:0051985;negative regulation of cell cycle#GO:0045786 intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779 MONDO|Ensembl=ENSMODG00000015631.4|UniProtKB=F7FET6 F7FET6 BARD1 PTHR24171:SF8 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1 MONDO|Ensembl=ENSMODG00000006599.3|UniProtKB=F7AK58 F7AK58 PTHR18914:SF30 ALPHA CATENIN VINCULIN_ALPHA-CATENIN FAMILY MEMBER 1 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;beta-catenin binding#GO:0008013 cell motility#GO:0048870;cell migration#GO:0016477;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 anchoring junction#GO:0070161;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000016752.4|UniProtKB=F6YL80 F6YL80 WDR24 PTHR46200:SF1 GATOR COMPLEX PROTEIN WDR24 GATOR2 COMPLEX PROTEIN WDR24 positive regulation of TOR signaling#GO:0032008;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular response to nutrient levels#GO:0031669;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;positive regulation of macroautophagy#GO:0016239;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;regulation of macroautophagy#GO:0016241;cellular response to amino acid starvation#GO:0034198;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 vacuolar membrane#GO:0005774;Seh1-associated complex#GO:0035859;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000007798.3|UniProtKB=F7A8C7 F7A8C7 BORCS6 PTHR13440:SF8 BLOC-1 RELATED COMPLEX SUBUNIT 6 BLOC-1-RELATED COMPLEX SUBUNIT 6 lysosome localization#GO:0032418;organelle localization#GO:0051640;localization#GO:0051179 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000000813.3|UniProtKB=F6S9Q4 F6S9Q4 MED28 PTHR13512:SF2 MEDIATOR COMPLEX SUBUNIT 28 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 28 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000020692.4|UniProtKB=F7DKF4 F7DKF4 AASDH PTHR44394:SF1 BETA-ALANINE-ACTIVATING ENZYME BETA-ALANINE-ACTIVATING ENZYME metabolite interconversion enzyme#PC00262;ligase#PC00142 MONDO|Ensembl=ENSMODG00000003429.4|UniProtKB=F7GCD0 F7GCD0 TMEM82 PTHR35257:SF1 TRANSMEMBRANE PROTEIN 82 TRANSMEMBRANE PROTEIN 82 MONDO|Ensembl=ENSMODG00000014175.4|UniProtKB=F6U7B4 F6U7B4 TBCB PTHR18916:SF97 DYNACTIN 1-RELATED MICROTUBULE-BINDING TUBULIN-FOLDING COFACTOR B microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 microtubule-based process#GO:0007017;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cytoplasmic microtubule organization#GO:0031122 cell cortex#GO:0005938;microtubule end#GO:1990752;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;cell periphery#GO:0071944;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000044611.1|UniProtKB=A0A5F8GEI1 A0A5F8GEI1 PTHR10369:SF3 60S RIBOSOMAL PROTEIN L36A/L44 RIBOSOMAL PROTEIN L36A structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000018147.5|UniProtKB=F7CXA7 F7CXA7 CFAP44 PTHR14885:SF3 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 44 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;sperm motility#GO:0097722;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458 membraneless organelle#GO:0043228;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995 MONDO|Ensembl=ENSMODG00000020487.4|UniProtKB=F7F5F8 F7F5F8 TMTC2 PTHR44216:SF3 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000036961.1|UniProtKB=A0A5F8H422 A0A5F8H422 OR12D3 PTHR26451:SF819 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 12D3 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000010466.3|UniProtKB=F7F7J7 F7F7J7 PLEKHO2 PTHR15871:SF2 PH DOMAIN-CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY O MEMBER 2 cell death#GO:0008219;apoptotic process#GO:0006915;cellular process#GO:0009987;programmed cell death#GO:0012501 MONDO|Ensembl=ENSMODG00000010898.4|UniProtKB=F7FIU7 F7FIU7 SNX1 PTHR10555:SF129 SORTING NEXIN SORTING NEXIN-1 phosphatidylinositol binding#GO:0035091;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;retromer complex#GO:0030904;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000025680.3|UniProtKB=F6U094 F6U094 PTHR28625:SF1 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 35 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 35 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cilium assembly#GO:1902017;regulation of cell projection organization#GO:0031344;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;positive regulation of organelle organization#GO:0010638;regulation of cell projection assembly#GO:0060491;regulation of microtubule-based process#GO:0032886;positive regulation of cell projection organization#GO:0031346;positive regulation of cellular component organization#GO:0051130;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000007423.4|UniProtKB=F6YZ23 F6YZ23 DNAH2 PTHR10676:SF183 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 2 polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;microtubule motor activity#GO:0003777;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based process#GO:0007017;cilium-dependent cell motility#GO:0060285 dynein complex#GO:0030286;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;catalytic complex#GO:1902494;cilium#GO:0005929;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000024766.1|UniProtKB=F7DAY4 F7DAY4 P2RY12 PTHR24233:SF0 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 12 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028096.2|UniProtKB=K7E6D5 K7E6D5 LOC100032606 PTHR47901:SF6 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18 CASPASE 4 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 regulation of response to stress#GO:0080134;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;biological regulation#GO:0065007;proteolysis#GO:0006508;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;canonical inflammasome complex#GO:0061702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000001709.4|UniProtKB=F6RMC1 F6RMC1 PTHR24291:SF149 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4B1 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000047337.1|UniProtKB=F7ETY5 F7ETY5 TUFT1 PTHR23171:SF4 GDOWN1 TUFTELIN intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II, core complex#GO:0005665;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;I band#GO:0031674;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;supramolecular fiber#GO:0099512;myofibril#GO:0030016;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;nuclear protein-containing complex#GO:0140513;sarcomere#GO:0030017 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000003798.4|UniProtKB=F6ZK39 F6ZK39 KCNH2 PTHR10217:SF506 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED INWARDLY RECTIFYING POTASSIUM CHANNEL KCNH2 passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000018987.3|UniProtKB=F7FP07 F7FP07 TBCC PTHR15139:SF0 TUBULIN FOLDING COFACTOR C TUBULIN-SPECIFIC CHAPERONE C cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000011516.5|UniProtKB=F6RI44 F6RI44 ITGA2B PTHR23220:SF73 INTEGRIN ALPHA INTEGRIN ALPHA-IIB signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;tube development#GO:0035295;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;system development#GO:0048731;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;circulatory system development#GO:0072359;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;integrin-mediated signaling pathway#GO:0007229;blood vessel morphogenesis#GO:0048514 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 integrin#PC00126;cell adhesion molecule#PC00069 Blood coagulation#P00011>GP IIb#P00410;Integrin signalling pathway#P00034>Integrin alpha#P00941 MONDO|Ensembl=ENSMODG00000014659.4|UniProtKB=A0A5F8HJT7 A0A5F8HJT7 PTHR15751:SF14 TRAFFICKING KINESIN-BINDING PROTEIN HUNTINGTIN-ASSOCIATED PROTEIN 1 binding#GO:0005488;myosin binding#GO:0017022;signaling receptor binding#GO:0005102;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;protein targeting#GO:0006605;establishment of organelle localization#GO:0051656;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular localization#GO:0051641;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;microtubule-based transport#GO:0099111;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;nervous system development#GO:0007399;establishment of protein localization#GO:0045184;signal transduction#GO:0007165;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;multicellular organism development#GO:0007275;microtubule-based process#GO:0007017;cell surface receptor signaling pathway#GO:0007166;response to growth factor#GO:0070848;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;localization#GO:0051179;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;organelle localization#GO:0051640;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;vesicle localization#GO:0051648;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;vesicle cytoskeletal trafficking#GO:0099518;neurogenesis#GO:0022008;mitochondrion localization#GO:0051646;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;developmental process#GO:0032502;transport#GO:0006810 intracellular vesicle#GO:0097708;vesicle#GO:0031982;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737 membrane traffic protein#PC00150 Huntington disease#P00029>HAP1#P00762 MONDO|Ensembl=ENSMODG00000006501.4|UniProtKB=F7EKI1 F7EKI1 TTC21B PTHR14699:SF1 STI2 PROTEIN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 21B microtubule-based transport#GO:0099111;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;protein localization to cilium#GO:0061512;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;intraciliary retrograde transport#GO:0035721;protein localization to organelle#GO:0033365;microtubule-based movement#GO:0007018;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705 intraciliary transport particle#GO:0030990;protein-containing complex#GO:0032991;intraciliary transport particle A#GO:0030991 MONDO|Ensembl=ENSMODG00000023124.3|UniProtKB=F6YY43 F6YY43 PTHR44873:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL chaperone#PC00072 MONDO|Ensembl=ENSMODG00000016412.5|UniProtKB=F7AT45 F7AT45 SLX4 PTHR21541:SF3 BTB POZ DOMAIN CONTAINING 12 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX4 reproductive process#GO:0022414;homologous recombination#GO:0035825;meiosis I#GO:0007127;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;meiotic cell cycle process#GO:1903046;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cell cycle process#GO:0022402;reciprocal homologous recombination#GO:0140527;organelle fission#GO:0048285;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;sexual reproduction#GO:0019953;nucleobase-containing compound metabolic process#GO:0006139;organelle organization#GO:0006996;cellular process#GO:0009987;resolution of meiotic recombination intermediates#GO:0000712;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA recombination#GO:0006310 chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000043399.1|UniProtKB=F7A1K6 F7A1K6 LOC100024194 PTHR26450:SF23 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E5 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027830.2|UniProtKB=K7E1T4 K7E1T4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000051024.1|UniProtKB=A0A5F8GZ62 A0A5F8GZ62 LOC100026660 PTHR24028:SF133 CADHERIN-87A PROTOCADHERIN ALPHA-9 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000017747.4|UniProtKB=F7EKT9 F7EKT9 SERINC4 PTHR10383:SF5 SERINE INCORPORATOR SERINE INCORPORATOR 4 cellular anatomical structure#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000013918.3|UniProtKB=F6SVB3 F6SVB3 RBM7 PTHR13798:SF4 RNA BINDING MOTIF RBM PROTEIN -RELATED RNA-BINDING PROTEIN 7 RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;binding#GO:0005488 biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000001792.5|UniProtKB=F6WIE9 F6WIE9 GDF5 PTHR11848:SF44 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 5 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;positive regulation of cell differentiation#GO:0045597;cell surface receptor signaling pathway#GO:0007166;regulation of cell differentiation#GO:0045595;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;positive regulation of developmental process#GO:0051094;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of multicellular organismal development#GO:2000026;BMP signaling pathway#GO:0030509;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of developmental process#GO:0050793;signaling#GO:0023052 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000023109.2|UniProtKB=Q2AB93 Q2AB93 T2R26 PTHR11394:SF58 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 7 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028227.2|UniProtKB=K7E553 K7E553 PTHR14759:SF34 STOP PROTEIN MUCIN-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;localization#GO:0051179;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;microtubule#GO:0005874;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cis-Golgi network#GO:0005801 MONDO|Ensembl=ENSMODG00000040493.1|UniProtKB=A0A5F8H1P5 A0A5F8H1P5 LOC103097016 PTHR16675:SF67 MHC CLASS I-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000012741.4|UniProtKB=F6TGM5 F6TGM5 TTC23 PTHR14485:SF3 TETRATRICOPEPTIDE REPEAT PROTEIN 23 TETRATRICOPEPTIDE REPEAT PROTEIN 23 MONDO|Ensembl=ENSMODG00000017357.4|UniProtKB=F6VZY0 F6VZY0 AZIN2 PTHR11482:SF4 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ANTIZYME INHIBITOR 2 molecular function regulator activity#GO:0098772;carbon-carbon lyase activity#GO:0016830;enzyme activator activity#GO:0008047;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;molecular function activator activity#GO:0140677;ornithine decarboxylase activity#GO:0004586;lyase activity#GO:0016829;enzyme regulator activity#GO:0030234 regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of transmembrane transport#GO:0034762;negative regulation of biological process#GO:0048519;polyamine metabolic process#GO:0006595;regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;regulation of localization#GO:0032879;regulation of transport#GO:0051049;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;negative regulation of protein catabolic process#GO:0042177;polyamine biosynthetic process#GO:0006596;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;amine metabolic process#GO:0009308;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 MONDO|Ensembl=ENSMODG00000001710.4|UniProtKB=A0A5F8GMU5 A0A5F8GMU5 PTHR47905:SF1 UBIQUITIN-LIKE PROTEIN 4B UBIQUITIN-LIKE PROTEIN 4B MONDO|Ensembl=ENSMODG00000011609.4|UniProtKB=F6UHH2 F6UHH2 LOC100029725 PTHR31233:SF10 BICAUDAL D FAMILY MEMBER BICD CARGO ADAPTOR 2 LIKE L HOMEOLOG cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule anchoring at microtubule organizing center#GO:0072393;microtubule anchoring#GO:0034453;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of microtubule-based process#GO:0032886;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000009519.3|UniProtKB=F7EV24 F7EV24 PNLIPRP2 PTHR11610:SF165 LIPASE PANCREATIC LIPASE-RELATED PROTEIN 2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 organophosphate catabolic process#GO:0046434;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000019909.4|UniProtKB=A0A5F8G6A3 A0A5F8G6A3 SPI1 PTHR11849:SF16 ETS TRANSCRIPTION FACTOR PU.1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 Interleukin signaling pathway#P00036>Ets#P00989 MONDO|Ensembl=ENSMODG00000043798.1|UniProtKB=A0A5F8H671 A0A5F8H671 C2orf76 PTHR18444:SF9 UPF0538 FAMILY MEMBER UPF0538 PROTEIN C2ORF76 MONDO|Ensembl=ENSMODG00000027546.2|UniProtKB=K7E1P8 K7E1P8 LOC103103839 PTHR23098:SF17 AGAP001331-PA-RELATED MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000013859.4|UniProtKB=A0A5F8GAG7 A0A5F8GAG7 MAG PTHR12035:SF107 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN MYELIN-ASSOCIATED GLYCOPROTEIN organic acid binding#GO:0043177;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;carbohydrate derivative binding#GO:0097367 cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000020802.4|UniProtKB=H9H7N0 H9H7N0 NEXN PTHR10075:SF52 BASIGIN RELATED NEXILIN intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512;myofibril#GO:0030016;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;organelle#GO:0043226;I band#GO:0031674;membraneless organelle#GO:0043228;cell junction#GO:0030054;sarcomere#GO:0030017;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000011942.4|UniProtKB=H9H6I6 H9H6I6 ABCB7 PTHR24221:SF402 ATP-BINDING CASSETTE SUB-FAMILY B IRON-SULFUR CLUSTERS TRANSPORTER ABCB7, MITOCHONDRIAL transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;inorganic ion homeostasis#GO:0098771 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000041285.1|UniProtKB=F6T6S4 F6T6S4 PTHR26450:SF70 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR OLFR593 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007323.4|UniProtKB=A0A5F8GZ94 A0A5F8GZ94 RAP1B PTHR24070:SF393 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-1B-RELATED ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;negative regulation of cellular process#GO:0048523;cellular response to stimulus#GO:0051716;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of secretion#GO:0051046;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;regulation of exocytosis#GO:0017157;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;regulation of trans-synaptic signaling#GO:0099177;intracellular signaling cassette#GO:0141124;regulation of localization#GO:0032879;regulation of transport#GO:0051049;negative regulation of biological process#GO:0048519;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of neurotransmitter secretion#GO:0046928;signaling#GO:0023052;regulation of synaptic vesicle exocytosis#GO:2000300;regulation of neurotransmitter transport#GO:0051588;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 Gonadotropin-releasing hormone receptor pathway#P06664>Rap1b#G06881;Gonadotropin-releasing hormone receptor pathway#P06664>Rap1b#P06803;Gonadotropin-releasing hormone receptor pathway#P06664>Rap1b#G06668;Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 MONDO|Ensembl=ENSMODG00000039345.1|UniProtKB=A0A5F8GHP4 A0A5F8GHP4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024045.1|UniProtKB=F6YNL2 F6YNL2 PTHR12786:SF2 SPLICING FACTOR SF3A-RELATED SPLICING FACTOR 3A SUBUNIT 3 snoRNA binding#GO:0030515;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;U2 snRNP#GO:0005686;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000006642.4|UniProtKB=A0A5F8HEJ8 A0A5F8HEJ8 SDCCAG8 PTHR34343:SF1 SEROLOGICALLY DEFINED COLON CANCER ANTIGEN 8 SEROLOGICALLY DEFINED COLON CANCER ANTIGEN 8 cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;tube development#GO:0035295;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell migration#GO:0016477;developmental process#GO:0032502;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;neurogenesis#GO:0022008;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;neuron migration#GO:0001764;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;establishment of cell polarity#GO:0030010;tube morphogenesis#GO:0035239;cellular component organization#GO:0016043;cell differentiation#GO:0030154;cell motility#GO:0048870;generation of neurons#GO:0048699;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226 microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000008164.2|UniProtKB=F7EL12 F7EL12 CHRM1 PTHR24247:SF182 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M1 neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;acetylcholine receptor activity#GO:0015464;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;molecular transducer activity#GO:0060089 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;trans-synaptic signaling#GO:0099537;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;dendrite#GO:0030425;dendritic tree#GO:0097447;cell junction#GO:0030054 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>mAChR1/3#P01069;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 MONDO|Ensembl=ENSMODG00000034930.2|UniProtKB=A0A5F8G239 A0A5F8G239 AJUBA PTHR24219:SF7 LIM DOMAIN-CONTAINING PROTEIN JUB LIM DOMAIN-CONTAINING PROTEIN AJUBA transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cell communication#GO:0010646;negative regulation of protein metabolic process#GO:0051248;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of response to stimulus#GO:0048583;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of signal transduction#GO:0009966;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of signaling#GO:0023051;negative regulation of translation#GO:0017148;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of hippo signaling#GO:0035331;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;miRNA-mediated post-transcriptional gene silencing#GO:0035195;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of hippo signaling#GO:0035330;negative regulation of metabolic process#GO:0009892;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of signal transduction#GO:0009968 adherens junction#GO:0005912;cell junction#GO:0030054;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;cell-cell junction#GO:0005911;membrane-bounded organelle#GO:0043227;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000017118.3|UniProtKB=F6U431 F6U431 ARRDC1 PTHR11188:SF182 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000006737.4|UniProtKB=F7CDC6 F7CDC6 FZD8 PTHR11309:SF90 FRIZZLED FRIZZLED-8 signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 biological regulation#GO:0065007;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;non-canonical Wnt signaling pathway#GO:0035567;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475;Angiogenesis#P00005>Fzd#P00189 MONDO|Ensembl=ENSMODG00000016422.4|UniProtKB=F7ASU7 F7ASU7 NAA60 PTHR14744:SF15 N-ALPHA-ACETYLTRANSFERASE 60 N-ALPHA-ACETYLTRANSFERASE 60 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;protein N-acyltransferase activity#GO:0140186 chromosome segregation#GO:0007059;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 transferase#PC00220;acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000008892.4|UniProtKB=F7BRI6 F7BRI6 DLX1 PTHR24327:SF33 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;embryo development ending in birth or egg hatching#GO:0009792;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;skeletal system development#GO:0001501;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000005099.2|UniProtKB=F6ZEE7 F6ZEE7 OGG1 PTHR10242:SF2 8-OXOGUANINE DNA GLYCOSYLASE N-GLYCOSYLASE_DNA LYASE catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA N-glycosylase activity#GO:0019104;catalytic activity, acting on DNA#GO:0140097;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;base-excision repair#GO:0006284;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000018332.2|UniProtKB=F6PSQ7 F6PSQ7 PTHR19282:SF198 TETRASPANIN TETRASPANIN-11 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006693.5|UniProtKB=F7F258 F7F258 PLK1 PTHR24345:SF93 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;kinetochore#GO:0000776;spindle pole#GO:0000922;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000011747.4|UniProtKB=F7DFB0 F7DFB0 STAT1 PTHR11801:SF18 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA_BETA DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;cellular response to cytokine stimulus#GO:0071345;response to peptide#GO:1901652;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;response to oxygen-containing compound#GO:1901700;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;defense response to other organism#GO:0098542;interleukin-9-mediated signaling pathway#GO:0038113;cell surface receptor signaling pathway via STAT#GO:0097696;response to biotic stimulus#GO:0009607;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;response to hormone#GO:0009725;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;interleukin-7-mediated signaling pathway#GO:0038111;response to lipopolysaccharide#GO:0032496;cell surface receptor signaling pathway#GO:0007166;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;lipopolysaccharide-mediated signaling pathway#GO:0031663;response to bacterium#GO:0009617;cytokine-mediated signaling pathway#GO:0019221;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;response to peptide hormone#GO:0043434;response to other organism#GO:0051707;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;immune response#GO:0006955;cellular response to molecule of bacterial origin#GO:0071219;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;cell surface receptor signaling pathway via JAK-STAT#GO:0007259 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>STAT#P00832;JAK/STAT signaling pathway#P00038>STAT#P01027;Oxidative stress response#P00046>Stat1#P01125;Oxidative stress response#P00046>Myc#P01124;EGF receptor signaling pathway#P00018>STAT#P00561;PDGF signaling pathway#P00047>STAT#P01173;Interferon-gamma signaling pathway#P00035>STAT1#P00961;Angiogenesis#P00005>STAT1#P00218;Ras Pathway#P04393>Stat 1/3#P04566;p53 pathway feedback loops 2#P04398>Myc#P04649;Interleukin signaling pathway#P00036>STAT#P00996 MONDO|Ensembl=ENSMODG00000005064.4|UniProtKB=F7ASK3 F7ASK3 ST14 PTHR24253:SF50 TRANSMEMBRANE PROTEASE SERINE SUPPRESSOR OF TUMORIGENICITY 14 PROTEIN catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233 cell differentiation#GO:0030154;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;proteolysis#GO:0006508;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;protein maturation#GO:0051604;epidermal cell differentiation#GO:0009913;gene expression#GO:0010467;epithelium development#GO:0060429;skin development#GO:0043588;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;animal organ development#GO:0048513;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;epidermis development#GO:0008544;metabolic process#GO:0008152;developmental process#GO:0032502 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000007760.4|UniProtKB=F7BJ22 F7BJ22 KIF5B PTHR24115:SF513 KINESIN-RELATED KINESIN-1 HEAVY CHAIN protein binding#GO:0005515;plus-end-directed microtubule motor activity#GO:0008574;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631 cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;axo-dendritic transport#GO:0008088;synaptic vesicle transport#GO:0048489;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;mitochondrion localization#GO:0051646;vesicle cytoskeletal trafficking#GO:0099518;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;axonal transport#GO:0098930;anterograde axonal transport#GO:0008089;cellular localization#GO:0051641;localization#GO:0051179 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000011001.4|UniProtKB=F7A143 F7A143 MEX3C PTHR23285:SF8 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING E3 UBIQUITIN-PROTEIN LIGASE MEX3C RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000010469.2|UniProtKB=F7F7I1 F7F7I1 GINS4 PTHR21206:SF0 SLD5 PROTEIN DNA REPLICATION COMPLEX GINS PROTEIN SLD5 cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725 DNA replication preinitiation complex#GO:0031261;chromosome#GO:0005694;organelle lumen#GO:0043233;GINS complex#GO:0000811;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000014165.4|UniProtKB=F6U7N1 F6U7N1 MYOM2 PTHR13817:SF22 TITIN MYOMESIN-2 structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;cell differentiation#GO:0030154;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;actomyosin structure organization#GO:0031032;cell development#GO:0048468;muscle cell development#GO:0055001;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;anatomical structure morphogenesis#GO:0009653;muscle cell differentiation#GO:0042692 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;contractile muscle fiber#GO:0043292;A band#GO:0031672;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular organelle#GO:0043229;M band#GO:0031430 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000039843.1|UniProtKB=A0A5F8GEF0 A0A5F8GEF0 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000006663.3|UniProtKB=A0A5F8GU73 A0A5F8GU73 DCTN5 PTHR46126:SF1 DYNACTIN SUBUNIT 5 DYNACTIN SUBUNIT 5 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000028755.2|UniProtKB=K7E503 K7E503 PTHR24256:SF577 TRYPTASE-RELATED INACTIVE SERINE PROTEASE 54 catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000004781.4|UniProtKB=A0A5F8HHB5 A0A5F8HHB5 SETD5 PTHR46462:SF1 UPSET, ISOFORM A HISTONE-LYSINE N-METHYLTRANSFERASE SETD5 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Rpd3L-Expanded complex#GO:0070210;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000005322.4|UniProtKB=A0A5F8HI52 A0A5F8HI52 NTM PTHR42757:SF9 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED NEUROTRIMIN regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;cell adhesion#GO:0007155;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of synapse assembly#GO:0051963;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007 synaptic membrane#GO:0097060;cell junction#GO:0030054;presynaptic active zone#GO:0048786;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;presynaptic active zone membrane#GO:0048787;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202 immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000021128.4|UniProtKB=F6QWX8 F6QWX8 FTHL17 PTHR11431:SF54 FERRITIN FERRITIN ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;ferrous iron binding#GO:0008198;iron ion binding#GO:0005506 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 storage protein#PC00210 MONDO|Ensembl=ENSMODG00000020827.4|UniProtKB=A0A5F8GSL8 A0A5F8GSL8 HAS1 PTHR22913:SF4 HYALURONAN SYNTHASE HYALURONAN SYNTHASE 1 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;glycosaminoglycan biosynthetic process#GO:0006024;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;extracellular matrix assembly#GO:0085029;cellular component assembly#GO:0022607;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;extracellular structure organization#GO:0043062;aminoglycan metabolic process#GO:0006022;polysaccharide biosynthetic process#GO:0000271;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan metabolic process#GO:0030203;primary metabolic process#GO:0044238;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000013158.4|UniProtKB=F6ZM50 F6ZM50 CHD2 PTHR45623:SF19 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD2 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;histone binding#GO:0042393;catalytic activity, acting on a nucleic acid#GO:0140640;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;DNA binding#GO:0003677 protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000047313.1|UniProtKB=A0A5F8H644 A0A5F8H644 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000641.4|UniProtKB=F6SUT9 F6SUT9 PACRGL PTHR21207:SF1 PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED PACRG-LIKE PROTEIN MONDO|Ensembl=ENSMODG00000038142.1|UniProtKB=A0A5F8GIN1 A0A5F8GIN1 LOC100011172 PTHR31475:SF6 UPF0462 PROTEIN UPF0462 PROTEIN C4ORF33 HOMOLOG MONDO|Ensembl=ENSMODG00000044626.1|UniProtKB=K7E5S1 K7E5S1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013544.4|UniProtKB=F7C3M7 F7C3M7 SCN4B PTHR13869:SF14 MYELIN P0 RELATED SODIUM CHANNEL REGULATORY SUBUNIT BETA-4 protein binding#GO:0005515;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;binding#GO:0005488;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325 actin-mediated cell contraction#GO:0070252;regulation of heart contraction#GO:0008016;striated muscle contraction#GO:0006941;membrane depolarization#GO:0051899;heart process#GO:0003015;muscle system process#GO:0003012;action potential#GO:0001508;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;circulatory system process#GO:0003013;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;cardiac muscle cell action potential involved in contraction#GO:0086002;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;actin filament-based movement#GO:0030048;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;cardiac muscle cell contraction#GO:0086003;heart contraction#GO:0060047;system process#GO:0003008;regulation of system process#GO:0044057;muscle contraction#GO:0006936 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703 myelin protein#PC00161 MONDO|Ensembl=ENSMODG00000006250.4|UniProtKB=F7FE75 F7FE75 GDE1 PTHR46320:SF1 GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1 GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;amine metabolic process#GO:0009308;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 phosphodiesterase#PC00185;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000018648.4|UniProtKB=F7B1X6 F7B1X6 SAP130 PTHR13497:SF3 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP130 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP130 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;chromosome#GO:0005694 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000042115.1|UniProtKB=A0A5F8G956 A0A5F8G956 SCNM1 PTHR32297:SF1 SODIUM CHANNEL MODIFIER 1 SODIUM CHANNEL MODIFIER 1 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000010808.5|UniProtKB=F7BZP8 F7BZP8 KLHL14 PTHR45632:SF6 LD33804P KELCH-LIKE PROTEIN 14 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 cell body#GO:0044297;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;neuron projection#GO:0043005;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004881.4|UniProtKB=F7C2Q6 F7C2Q6 FAM149A PTHR31997:SF2 AGAP003710-PA PROTEIN FAM149A MONDO|Ensembl=ENSMODG00000018646.5|UniProtKB=H9H762 H9H762 PTHR47282:SF1 PGC-1 AND ERR-INDUCED REGULATOR IN MUSCLE PROTEIN 1 PGC-1 AND ERR-INDUCED REGULATOR IN MUSCLE PROTEIN 1 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000027399.2|UniProtKB=K7E4G7 K7E4G7 PTHR45725:SF10 FORMIN HOMOLOGY 2 FAMILY MEMBER FH2 DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000016073.2|UniProtKB=F7G9T7 F7G9T7 LOC100023412 PTHR24242:SF378 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11A1 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000015432.4|UniProtKB=F6S2G2 F6S2G2 TEDC2 PTHR14870:SF1 TUBULIN EPSILON AND DELTA COMPLEX PROTEIN 2 TUBULIN EPSILON AND DELTA COMPLEX PROTEIN 2 MONDO|Ensembl=ENSMODG00000036596.1|UniProtKB=A0A5F8HHL4 A0A5F8HHL4 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000042725.1|UniProtKB=A0A5F8G6Z4 A0A5F8G6Z4 LOC100619815 PTHR24393:SF126 ZINC FINGER PROTEIN RB-ASSOCIATED KRAB ZINC FINGER PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018619.4|UniProtKB=H9H754 H9H754 TXNRD2 PTHR48105:SF21 THIOREDOXIN REDUCTASE 1-RELATED-RELATED THIOREDOXIN REDUCTASE 2, MITOCHONDRIAL protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;disulfide oxidoreductase activity#GO:0015036;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000000322.3|UniProtKB=F6VUC1 F6VUC1 PTHR11477:SF1 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 1 transcription regulator activity#GO:0140110;transcription elongation factor activity#GO:0003711 transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000019259.4|UniProtKB=A0A5F8HD33 A0A5F8HD33 ALDOC PTHR11627:SF3 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE C carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;fructose-bisphosphate aldolase activity#GO:0004332;aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829 ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523;ADP catabolic process#GO:0046032;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nicotinamide nucleotide metabolic process#GO:0046496;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 aldolase#PC00044;lyase#PC00144 Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959;Glycolysis#P00024>Aldolase#P00679 MONDO|Ensembl=ENSMODG00000010490.3|UniProtKB=F7ES90 F7ES90 PTHR26451:SF876 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10K2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000045510.1|UniProtKB=A0A5F8HIC7 A0A5F8HIC7 FADD PTHR48169:SF3 DED DOMAIN-CONTAINING PROTEIN CASP8 AND FADD-LIKE APOPTOSIS REGULATOR negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;negative regulation of programmed cell death#GO:0043069;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057 MONDO|Ensembl=ENSMODG00000013036.4|UniProtKB=A0A5F8GQ44 A0A5F8GQ44 SLC25A17 PTHR45939:SF5 PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED PEROXISOMAL MEMBRANE PROTEIN PMP34 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;purine nucleotide transmembrane transporter activity#GO:0015216;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000008473.4|UniProtKB=A0A5F8GIP5 A0A5F8GIP5 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002558.3|UniProtKB=A0A5F8GQT3 A0A5F8GQT3 PTHR11937:SF195 ACTIN BETA-CENTRACTIN structural molecule activity#GO:0005198;protein-membrane adaptor activity#GO:0043495;structural constituent of cytoskeleton#GO:0005200;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cytoskeletal adaptor activity#GO:0008093 microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;nuclear migration#GO:0007097 microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090 MONDO|Ensembl=ENSMODG00000025044.3|UniProtKB=F6W7J7 F6W7J7 BHLHA15 PTHR19290:SF160 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED CLASS A BASIC HELIX-LOOP-HELIX PROTEIN 15 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;neuron development#GO:0048666;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;plasma membrane bounded cell projection organization#GO:0120036;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;sensory organ development#GO:0007423;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000029131.2|UniProtKB=K7E6A1 K7E6A1 ABCC11 PTHR24223:SF168 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 11 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 bile acid and bile salt transport#GO:0015721;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;macromolecule localization#GO:0033036;lipid transport#GO:0006869 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000024870.2|UniProtKB=F6WFF1 F6WFF1 GPBAR1 PTHR24246:SF31 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR G PROTEIN-COUPLED BILE ACID RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell surface receptor signaling pathway#GO:0007166;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001246.4|UniProtKB=F7FWP6 F7FWP6 PTHR47743:SF1 KIAA1210 / KIAA1211 FAMILY MEMBER CRACD-LIKE PROTEIN MONDO|Ensembl=ENSMODG00000020553.3|UniProtKB=F7AQ39 F7AQ39 RPL9 PTHR11655:SF16 60S/50S RIBOSOMAL PROTEIN L6/L9 LARGE RIBOSOMAL SUBUNIT PROTEIN UL6 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000001184.4|UniProtKB=F7GHC1 F7GHC1 PTHR15725:SF2 ZN-FINGER, C-X8-C-X5-C-X3-H TYPE-CONTAINING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 11A mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 gene expression#GO:0010467;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;transport#GO:0006810;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000013138.3|UniProtKB=F7AZF2 F7AZF2 TLCD5 PTHR31898:SF1 TRANSMEMBRANE PROTEIN 136 TLC DOMAIN-CONTAINING PROTEIN 5 MONDO|Ensembl=ENSMODG00000001956.4|UniProtKB=F6VJA4 F6VJA4 TMEM144 PTHR16119:SF17 TRANSMEMBRANE PROTEIN 144 TRANSMEMBRANE PROTEIN 144 MONDO|Ensembl=ENSMODG00000044888.1|UniProtKB=A0A5F8GDP5 A0A5F8GDP5 LOC100027064 PTHR48018:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001082.4|UniProtKB=F7AYI9 F7AYI9 CHIT1 PTHR11177:SF407 CHITINASE CHITOTRIOSIDASE-1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568 chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;chitin metabolic process#GO:0006030;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000009670.2|UniProtKB=F6SHQ2 F6SHQ2 FGF17 PTHR11486:SF71 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 17 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;fibroblast growth factor receptor binding#GO:0005104;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;nervous system development#GO:0007399;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of cell migration#GO:0030334 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000010633.4|UniProtKB=F7D544 F7D544 PTHR11481:SF64 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;immune system process#GO:0002376;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000017149.4|UniProtKB=A0A5F8GKT0 A0A5F8GKT0 REPS2 PTHR11216:SF64 EH DOMAIN RALBP1-ASSOCIATED EPS DOMAIN-CONTAINING PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;import into cell#GO:0098657;establishment of localization#GO:0051234;endosomal transport#GO:0016197;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000014038.5|UniProtKB=F6UQI6 F6UQI6 ARHGAP33 PTHR15729:SF11 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 33 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000017587.4|UniProtKB=F7B563 F7B563 RIMS3 PTHR12157:SF25 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 3 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;regulation of synaptic vesicle exocytosis#GO:2000300;signaling#GO:0023052;export from cell#GO:0140352;regulation of neurotransmitter secretion#GO:0046928;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;regulation of localization#GO:0032879;exocytosis#GO:0006887;regulation of transport#GO:0051049;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;exocytic process#GO:0140029;regulated exocytosis#GO:0045055;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;regulation of exocytosis#GO:0017157;secretion#GO:0046903;regulation of secretion#GO:0051046;cell communication#GO:0007154;localization#GO:0051179;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 synaptic membrane#GO:0097060;cell junction#GO:0030054;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;presynapse#GO:0098793;cell cortex#GO:0005938;cell periphery#GO:0071944;plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;presynaptic membrane#GO:0042734 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000005362.4|UniProtKB=F6YLD9 F6YLD9 PTHR15583:SF10 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR E-LIKE PROTEIN molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;response to cytokine#GO:0034097;cell surface receptor signaling pathway#GO:0007166;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000049039.1|UniProtKB=F6SN42 F6SN42 LOC100033123 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020457.4|UniProtKB=A0A5F8G3S3 A0A5F8G3S3 CCDC68 PTHR23171:SF3 GDOWN1 COILED-COIL DOMAIN-CONTAINING PROTEIN 68 membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;I band#GO:0031674;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;RNA polymerase II, core complex#GO:0005665;intracellular membrane-bounded organelle#GO:0043231;nuclear DNA-directed RNA polymerase complex#GO:0055029;sarcomere#GO:0030017;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;contractile muscle fiber#GO:0043292;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000005749.3|UniProtKB=F6QDW8 F6QDW8 FIGN PTHR23074:SF14 AAA DOMAIN-CONTAINING FIDGETIN hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000019450.3|UniProtKB=F6RXG2 F6RXG2 COMMD7 PTHR16231:SF2 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 7 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;response to tumor necrosis factor#GO:0034612;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;tumor necrosis factor-mediated signaling pathway#GO:0033209;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000014314.4|UniProtKB=A0A5F8GFD5 A0A5F8GFD5 NCAM1 PTHR12231:SF239 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN NEURAL CELL ADHESION MOLECULE 1 protein binding#GO:0005515;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 system development#GO:0048731;anatomical structure development#GO:0048856;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neuron development#GO:0048666;axonogenesis#GO:0007409;cell adhesion#GO:0007155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;neuron projection development#GO:0031175;cell-cell adhesion#GO:0098609;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039 cell junction#GO:0030054;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000014843.5|UniProtKB=F7CHE6 F7CHE6 MLYCD PTHR28641:SF1 FAMILY NOT NAMED MALONYL-COA DECARBOXYLASE, MITOCHONDRIAL MONDO|Ensembl=ENSMODG00000050246.1|UniProtKB=F7E0K9 F7E0K9 PTHR48018:SF28 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8K3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017447.4|UniProtKB=F6ZTW3 F6ZTW3 PTHR15268:SF4 THRAP3/BCLAF1 BCL-2-ASSOCIATED TRANSCRIPTION FACTOR 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000045438.1|UniProtKB=A0A5F8H0R7 A0A5F8H0R7 SYS1 PTHR12952:SF0 SYS1 PROTEIN SYS1 HOMOLOG protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;Golgi to endosome transport#GO:0006895;Golgi to plasma membrane transport#GO:0006893;protein localization to organelle#GO:0033365;cytosolic transport#GO:0016482;Golgi to plasma membrane protein transport#GO:0043001;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;protein localization to cell periphery#GO:1990778;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000018827.3|UniProtKB=F7GKG5 F7GKG5 MINDY1 PTHR18063:SF7 NF-E2 INDUCIBLE PROTEIN UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-1 deubiquitinase activity#GO:0101005;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000020671.4|UniProtKB=F7A906 F7A906 KIT PTHR24416:SF46 TYROSINE-PROTEIN KINASE RECEPTOR MAST_STEM CELL GROWTH FACTOR RECEPTOR KIT molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515;kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023 positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;immune system process#GO:0002376;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;cell development#GO:0048468;positive regulation of cell population proliferation#GO:0008284;positive regulation of cell motility#GO:2000147;leukocyte differentiation#GO:0002521;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;mononuclear cell differentiation#GO:1903131;B cell activation#GO:0042113;cell surface receptor signaling pathway#GO:0007166;response to cytokine#GO:0034097;response to chemical#GO:0042221;lymphocyte activation#GO:0046649;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cytokine-mediated signaling pathway#GO:0019221;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;lymphocyte differentiation#GO:0030098;cell activation#GO:0001775;positive regulation of cell communication#GO:0010647;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;hemopoiesis#GO:0030097;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000036527.1|UniProtKB=A0A5F8GR83 A0A5F8GR83 PTHR11388:SF89 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1B1 transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804;bile acid transmembrane transporter activity#GO:0015125 monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;bile acid and bile salt transport#GO:0015721;lipid localization#GO:0010876;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transporter#PC00227 MONDO|Ensembl=ENSMODG00000013405.4|UniProtKB=F7CP16 F7CP16 LGALS4 PTHR11346:SF32 GALECTIN GALECTIN-4 carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000040769.1|UniProtKB=K7DZE8 K7DZE8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010916.3|UniProtKB=F7F5D7 F7F5D7 ERCC6L PTHR45629:SF13 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE DNA translocase activity#GO:0015616;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 damaged DNA-binding protein#PC00086 MONDO|Ensembl=ENSMODG00000018750.4|UniProtKB=F7EF34 F7EF34 PEX11B PTHR12652:SF7 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11B cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;organelle organization#GO:0006996;cellular component organization#GO:0016043;peroxisome organization#GO:0007031;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778 MONDO|Ensembl=ENSMODG00000021583.1|UniProtKB=Q65CI5 Q65CI5 MT-ND4L PTHR11434:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT ND4L NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4L transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000006268.3|UniProtKB=F7FDU0 F7FDU0 PTHR10093:SF26 IRON-SULFUR CLUSTER ASSEMBLY ENZYME NIFU HOMOLOG IRON-SULFUR CLUSTER ASSEMBLY ENZYME ISCU iron-sulfur cluster binding#GO:0051536;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;iron ion binding#GO:0005506;ferrous iron binding#GO:0008198 cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873 mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000018366.4|UniProtKB=F6RFU2 F6RFU2 CYB5R4 PTHR46237:SF2 CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER CYTOCHROME B5 REDUCTASE 4 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824 superoxide metabolic process#GO:0006801;cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 reductase#PC00198 MONDO|Ensembl=ENSMODG00000016878.3|UniProtKB=F6Y1D7 F6Y1D7 PTHR22803:SF116 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED REGENERATING ISLET-DERIVED PROTEIN 3-GAMMA receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;hormone activity#GO:0005179;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;regulation of cell population proliferation#GO:0042127;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to nitrogen compound#GO:1901698;immune system process#GO:0002376;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;defense response to other organism#GO:0098542;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to hormone#GO:0009725;defense response to symbiont#GO:0140546;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;response to external stimulus#GO:0009605;defense response#GO:0006952;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000025621.3|UniProtKB=F6XWY4 F6XWY4 DOK6 PTHR21258:SF43 DOCKING PROTEIN RELATED DOCKING PROTEIN 6 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005251.4|UniProtKB=F7GH27 F7GH27 UGT8 PTHR48043:SF54 EG:EG0003.4 PROTEIN-RELATED 2-HYDROXYACYLSPHINGOSINE 1-BETA-GALACTOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378 lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;glycolipid biosynthetic process#GO:0009247;glycosphingolipid biosynthetic process#GO:0006688 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000043007.1|UniProtKB=A0A5F8H8H2 A0A5F8H8H2 PTHR10338:SF155 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H6 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000039120.1|UniProtKB=A0A5F8H0Z3 A0A5F8H0Z3 monDomV1R1250 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000036466.1|UniProtKB=F6YEM6 F6YEM6 PTHR26450:SF170 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E8 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000043105.1|UniProtKB=A0A5F8H850 A0A5F8H850 PTHR31796:SF2 SUZ DOMAIN-CONTAINING PROTEIN 1 SUZ RNA-BINDING DOMAIN-CONTAINING MONDO|Ensembl=ENSMODG00000005517.2|UniProtKB=F7G5K7 F7G5K7 NUTF2 PTHR12612:SF48 NUCLEAR TRANSPORT FACTOR 2 NUCLEAR TRANSPORT FACTOR 2 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000003696.3|UniProtKB=F7FAF7 F7FAF7 FMO2 PTHR23023:SF84 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824 response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000007785.3|UniProtKB=F7A9U2 F7A9U2 PTHR19282:SF234 TETRASPANIN ROD OUTER SEGMENT MEMBRANE PROTEIN 1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000015771.4|UniProtKB=F6ZS67 F6ZS67 CFTR PTHR24223:SF19 ATP-BINDING CASSETTE SUB-FAMILY C CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR gated channel activity#GO:0022836;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic ion channel activity#GO:0015276;polypeptide conformation or assembly isomerase activity#GO:0120544;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;transmembrane transporter activity#GO:0022857;macromolecular conformation isomerase activity#GO:0120543;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;catalytic activity#GO:0003824;isomerase activity#GO:0016853 chloride transmembrane transport#GO:1902476;water transport#GO:0006833;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;fluid transport#GO:0042044;monoatomic ion transport#GO:0006811;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cytosol#GO:0005829;apical plasma membrane#GO:0016324;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;intracellular anatomical structure#GO:0005622;apical part of cell#GO:0045177 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000005997.4|UniProtKB=A0A5F8G1R6 A0A5F8G1R6 PTHR45845:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED PURATROPHIN-1 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000020100.4|UniProtKB=F7ESB8 F7ESB8 SLC43A3 PTHR20765:SF1 SOLUTE CARRIER FAMILY 43 MEMBER 3-RELATED EQUILIBRATIVE NUCLEOBASE TRANSPORTER 1 secondary carrier transporter#PC00258;amino acid transporter#PC00046 MONDO|Ensembl=ENSMODG00000010584.3|UniProtKB=F7GHT5 F7GHT5 OSR1 PTHR14196:SF5 ODD-SKIPPED - RELATED PROTEIN ODD-SKIPPED-RELATED 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;kidney development#GO:0001822;renal system development#GO:0072001;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000043681.1|UniProtKB=A0A5F8G8K7 A0A5F8G8K7 PTHR23304:SF189 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000019475.4|UniProtKB=F6RB99 F6RB99 GZMA PTHR24271:SF69 KALLIKREIN-RELATED GRANZYME A serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;signal transduction#GO:0007165;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;cell communication#GO:0007154;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell death#GO:0008219;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000018904.3|UniProtKB=F7C7G1 F7C7G1 OAZ3 PTHR10279:SF9 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME 3 molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000007418.3|UniProtKB=F7EE69 F7EE69 PPME1 PTHR14189:SF0 PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED PROTEIN PHOSPHATASE METHYLESTERASE 1 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000025611.3|UniProtKB=F6QBD7 F6QBD7 XKR4 PTHR16024:SF16 XK-RELATED PROTEIN XK-RELATED PROTEIN 4 developmental process#GO:0032502;transport#GO:0006810;phagocytosis#GO:0006909;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;localization#GO:0051179;anatomical structure development#GO:0048856;cell death#GO:0008219;programmed cell death#GO:0012501;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;membrane invagination#GO:0010324;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;apoptotic cell clearance#GO:0043277;import into cell#GO:0098657;cellular process#GO:0009987;endomembrane system organization#GO:0010256;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cellular component organization#GO:0016043;endocytosis#GO:0006897 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000047059.1|UniProtKB=A0A5F8HCY3 A0A5F8HCY3 DACT3 PTHR15919:SF1 DAPPER-RELATED DAPPER HOMOLOG 3 negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000007492.4|UniProtKB=A0A5F8GFM8 A0A5F8GFM8 ZSCAN16 PTHR23226:SF52 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 16 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000045306.1|UniProtKB=A0A5F8G8P8 A0A5F8G8P8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013877.3|UniProtKB=F6W8J7 F6W8J7 FFAR1 PTHR45822:SF4 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 1 bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of protein secretion#GO:0050708;cellular response to stimulus#GO:0051716;regulation of establishment of protein localization#GO:0070201;response to fatty acid#GO:0070542;cell communication#GO:0007154;regulation of secretion#GO:0051046;positive regulation of hormone secretion#GO:0046887;response to chemical#GO:0042221;response to lipid#GO:0033993;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;cellular process#GO:0009987;regulation of insulin secretion#GO:0050796;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of protein secretion#GO:0050714;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of protein transport#GO:0051223;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;regulation of hormone secretion#GO:0046883;positive regulation of signaling#GO:0023056;response to oxygen-containing compound#GO:1901700;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000041010.1|UniProtKB=A0A5F8HAM8 A0A5F8HAM8 LOC103102859 PTHR11960:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 1B nucleic acid binding#GO:0003676;binding#GO:0005488;translation factor activity#GO:0180051;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000041650.1|UniProtKB=A0A5F8HIY2 A0A5F8HIY2 PTHR42707:SF2 ACYL-COA DEHYDROGENASE ACD11 DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000014325.4|UniProtKB=A0A5F8GBK0 A0A5F8GBK0 PPM1H PTHR13832:SF287 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1H hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000025433.3|UniProtKB=F6VLV3 F6VLV3 ZBED4 PTHR46481:SF15 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 MONDO|Ensembl=ENSMODG00000024673.2|UniProtKB=F6U039 F6U039 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000005650.4|UniProtKB=F7BW45 F7BW45 ADRB2 PTHR24248:SF21 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR BETA-2 ADRENERGIC RECEPTOR cation binding#GO:0043169;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;G protein-coupled amine receptor activity#GO:0008227 cell communication#GO:0007154;regulation of biological quality#GO:0065008;adrenergic receptor signaling pathway#GO:0071875;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;vasodilation#GO:0042311;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;system process#GO:0003008;regulation of anatomical structure size#GO:0090066;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;biological regulation#GO:0065007;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;cellular process#GO:0009987;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Beta2 adrenergic receptor signaling pathway#P04378>Beta2#P04440 MONDO|Ensembl=ENSMODG00000021271.5|UniProtKB=F6T2U7 F6T2U7 TSC22D2 PTHR46894:SF1 TSC22 DOMAIN FAMILY PROTEIN 2 TSC22 DOMAIN FAMILY PROTEIN 2 MONDO|Ensembl=ENSMODG00000011194.4|UniProtKB=F6T6Q0 F6T6Q0 EXOSC10 PTHR12124:SF47 POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED EXOSOME COMPLEX COMPONENT 10 MONDO|Ensembl=ENSMODG00000011255.3|UniProtKB=F6R1U9 F6R1U9 LOC100618852 PTHR26450:SF63 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52Z1P olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021531.3|UniProtKB=F7E0A8 F7E0A8 MYPOP PTHR32345:SF3 MYB-RELATED TRANSCRIPTION FACTOR, PARTNER OF PROFILIN MYB-RELATED TRANSCRIPTION FACTOR, PARTNER OF PROFILIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000044740.1|UniProtKB=F7DDF1 F7DDF1 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000041843.1|UniProtKB=A0A5F8GPH0 A0A5F8GPH0 FAM83E PTHR16181:SF36 PROTEIN FAM83A-RELATED PROTEIN FAM83E protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 MONDO|Ensembl=ENSMODG00000011923.4|UniProtKB=A0A5F8H9A0 A0A5F8H9A0 PTHR16230:SF4 CAPPUCCINO BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 4 melanosome organization#GO:0032438;platelet aggregation#GO:0070527;vesicle organization#GO:0016050;blood coagulation#GO:0007596;cellular component organization or biogenesis#GO:0071840;platelet activation#GO:0030168;cellular process#GO:0009987;coagulation#GO:0050817;response to wounding#GO:0009611;cell-cell adhesion#GO:0098609;response to stress#GO:0006950;organelle organization#GO:0006996;homotypic cell-cell adhesion#GO:0034109;cellular pigmentation#GO:0033059;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell activation#GO:0001775;pigmentation#GO:0043473;cell adhesion#GO:0007155;regulation of biological quality#GO:0065008;wound healing#GO:0042060;cellular component organization#GO:0016043;hemostasis#GO:0007599;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896 BLOC-1 complex#GO:0031083;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000012451.3|UniProtKB=F6PI20 F6PI20 CDK2AP1 PTHR22607:SF2 DELETED IN ORAL CANCER 1/CDK2-ASSOCIATED PROTEIN 1 CYCLIN-DEPENDENT KINASE 2-ASSOCIATED PROTEIN 1 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase modulator#PC00140;kinase inhibitor#PC00139 MONDO|Ensembl=ENSMODG00000000951.4|UniProtKB=F7CJP1 F7CJP1 DNAI4 PTHR12442:SF12 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 4 protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;cilium movement#GO:0003341;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axonemal dynein complex#GO:0005858;dynein complex#GO:0030286;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000013139.3|UniProtKB=F7AZE3 F7AZE3 SLC25A47 PTHR45624:SF3 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 47 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 MONDO|Ensembl=ENSMODG00000014411.4|UniProtKB=F7C1U2 F7C1U2 EXOC4 PTHR14146:SF4 EXOCYST COMPLEX COMPONENT 4 EXOCYST COMPLEX COMPONENT 4 synaptic signaling#GO:0099536;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;transport#GO:0006810;establishment of localization#GO:0051234;exocytosis#GO:0006887;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;export from cell#GO:0140352;trans-synaptic signaling#GO:0099537;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;secretion by cell#GO:0032940 site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;axon#GO:0030424;growth cone#GO:0030426;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cell cortex#GO:0005938;cell junction#GO:0030054;vesicle tethering complex#GO:0099023;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;exocyst#GO:0000145;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000004328.4|UniProtKB=F6X6T6 F6X6T6 C9orf72 PTHR31855:SF2 GUANINE NUCLEOTIDE EXCHANGE C9ORF72 GUANINE NUCLEOTIDE EXCHANGE FACTOR C9ORF72 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 regulation of response to stimulus#GO:0048583;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of TOR signaling#GO:0032006;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;localization#GO:0051179;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 endosome#GO:0005768;intracellular organelle#GO:0043229;autophagosome#GO:0005776;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000021413.3|UniProtKB=F7CBR7 F7CBR7 MC2R PTHR22750:SF3 G-PROTEIN COUPLED RECEPTOR ADRENOCORTICOTROPIC HORMONE RECEPTOR transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000006526.4|UniProtKB=F7E3K1 F7E3K1 SOX9 PTHR45803:SF1 SOX100B TRANSCRIPTION FACTOR SOX-9 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;cartilage development#GO:0051216;regulation of RNA metabolic process#GO:0051252;tissue morphogenesis#GO:0048729;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;connective tissue development#GO:0061448;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;chondrocyte differentiation#GO:0002062;tissue development#GO:0009888;oligodendrocyte differentiation#GO:0048709;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;skeletal system development#GO:0001501;negative regulation of DNA-templated transcription#GO:0045892;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;cell differentiation#GO:0030154;circulatory system development#GO:0072359;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of cell differentiation#GO:0045597;gliogenesis#GO:0042063;morphogenesis of an epithelium#GO:0002009;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;heart development#GO:0007507 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 MONDO|Ensembl=ENSMODG00000006559.4|UniProtKB=A0A5F8G4H9 A0A5F8G4H9 ADSS PTHR11846:SF13 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE ISOZYME 2 ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;IMP metabolic process#GO:0046040;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;nucleoside phosphate biosynthetic process#GO:1901293;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;ligase#PC00142 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890 MONDO|Ensembl=ENSMODG00000018734.3|UniProtKB=F7EY56 F7EY56 LOC100618180 PTHR26452:SF204 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000001579.4|UniProtKB=A0A5F8HHG5 A0A5F8HHG5 CRY1 PTHR11455:SF16 CRYPTOCHROME CRYPTOCHROME-1 carbon-carbon lyase activity#GO:0016830;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;lyase activity#GO:0016829;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleic acid binding#GO:0003676;deoxyribodipyrimidine photo-lyase activity#GO:0003904;DNA binding#GO:0003677 negative regulation of biological process#GO:0048519;response to abiotic stimulus#GO:0009628;circadian regulation of gene expression#GO:0032922;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;rhythmic process#GO:0048511;negative regulation of DNA-templated transcription#GO:0045892;circadian rhythm#GO:0007623;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of macromolecule metabolic process#GO:0060255;response to light stimulus#GO:0009416;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of circadian rhythm#GO:0042752;response to radiation#GO:0009314;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;photoperiodism#GO:0009648;regulation of biosynthetic process#GO:0009889;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DNA photolyase#PC00014 Circadian clock system#P00015>cry#G01497;Circadian clock system#P00015>cry#G01501;Circadian clock system#P00015>Cry#P00505 MONDO|Ensembl=ENSMODG00000018783.3|UniProtKB=F7AD79 F7AD79 MRPS21 PTHR21109:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S21 SMALL RIBOSOMAL SUBUNIT PROTEIN BS21M translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000003729.3|UniProtKB=F7EVS6 F7EVS6 COPE PTHR10805:SF0 COATOMER SUBUNIT EPSILON COATOMER SUBUNIT EPSILON localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810 coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020 vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000024516.1|UniProtKB=F7EB83 F7EB83 LOC100028544 PTHR48002:SF88 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028732.2|UniProtKB=H9H6S5 H9H6S5 LOC103105268 PTHR24377:SF878 IP01015P-RELATED ZINC FINGER PROTEIN 670 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016287.5|UniProtKB=F7AU53 F7AU53 BMPR2 PTHR23255:SF63 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-2 catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transforming growth factor beta receptor activity#GO:0005024;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;transmembrane signaling receptor activity#GO:0004888 response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;blood vessel development#GO:0001568;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;response to stimulus#GO:0050896;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;vasculature development#GO:0001944 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>BMPR-IA/IB/II#P06740 MONDO|Ensembl=ENSMODG00000001609.4|UniProtKB=A0A5F8HBF7 A0A5F8HBF7 LOC100017133 PTHR23023:SF131 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000024148.1|UniProtKB=F6U3G0 F6U3G0 CLP1 PTHR12755:SF6 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;phosphotransferase activity, alcohol group as acceptor#GO:0016773 RNA splicing#GO:0008380;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000000487.4|UniProtKB=F6UA26 F6UA26 OTUD4 PTHR12419:SF9 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 4 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 negative regulation of cell communication#GO:0010648;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;negative regulation of signaling#GO:0023057;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;negative regulation of response to cytokine stimulus#GO:0060761;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cytokine-mediated signaling pathway#GO:0001959;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;negative regulation of cytokine-mediated signaling pathway#GO:0001960;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;negative regulation of signal transduction#GO:0009968;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of response to cytokine stimulus#GO:0060759 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000019796.4|UniProtKB=F6TA67 F6TA67 ANGPTL2 PTHR19143:SF24 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 2 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000004999.3|UniProtKB=F7F741 F7F741 MTNR1A PTHR24228:SF53 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR MELATONIN RECEPTOR TYPE 1A G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 MONDO|Ensembl=ENSMODG00000039982.1|UniProtKB=A0A5F8HE40 A0A5F8HE40 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009999.4|UniProtKB=F6URW8 F6URW8 DPYSL3 PTHR11647:SF57 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;dihydropyrimidinase activity#GO:0004157;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 nucleobase catabolic process#GO:0046113;actin cytoskeleton organization#GO:0030036;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;pyrimidine nucleobase catabolic process#GO:0006208;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;nucleobase-containing compound metabolic process#GO:0006139;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;organelle organization#GO:0006996;nucleobase metabolic process#GO:0009112;actin filament organization#GO:0007015;nucleobase-containing small molecule metabolic process#GO:0055086;pyrimidine nucleobase metabolic process#GO:0006206;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 MONDO|Ensembl=ENSMODG00000009579.4|UniProtKB=A0A5F8GUR6 A0A5F8GUR6 SLC45A1 PTHR19432:SF6 SUGAR TRANSPORTER PROTON-ASSOCIATED SUGAR TRANSPORTER A solute:proton symporter activity#GO:0015295;symporter activity#GO:0015293;carbohydrate transmembrane transporter activity#GO:0015144;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000018311.4|UniProtKB=F6PUL4 F6PUL4 PTHR12622:SF41 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX3L acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000039889.1|UniProtKB=A0A5F8GRH8 A0A5F8GRH8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010240.4|UniProtKB=F6WLC3 F6WLC3 PROSER1 PTHR14880:SF2 PROLINE AND SERINE-RICH PROTEIN 1 PROLINE AND SERINE-RICH PROTEIN 1 MONDO|Ensembl=ENSMODG00000002850.4|UniProtKB=A0A5F8HEL8 A0A5F8HEL8 FAM161A PTHR21501:SF3 PROTEIN FAM-161 PROTEIN FAM161A cilium organization#GO:0044782;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;9+0 non-motile cilium#GO:0097731;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;ciliary transition zone#GO:0035869;cilium#GO:0005929 MONDO|Ensembl=ENSMODG00000039528.1|UniProtKB=A0A5F8H5J5 A0A5F8H5J5 monDomV1R1220 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003052.4|UniProtKB=F6PNZ1 F6PNZ1 CCDC181 PTHR14320:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 181 COILED-COIL DOMAIN-CONTAINING PROTEIN 181 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 MONDO|Ensembl=ENSMODG00000005519.4|UniProtKB=F7G594 F7G594 PTHR21312:SF28 SERINE PROTEASE INHIBITOR OVOINHIBITOR-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000024112.4|UniProtKB=F6WJI3 F6WJI3 TMEM134 PTHR13558:SF1 TRANSMEMBRANE PROTEIN 134 TRANSMEMBRANE PROTEIN 134 MONDO|Ensembl=ENSMODG00000007796.3|UniProtKB=F7A8G2 F7A8G2 PTHR24237:SF38 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000051190.1|UniProtKB=A0A5F8GX65 A0A5F8GX65 TAF11 PTHR13218:SF8 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11 protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840 transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013 RNA metabolism protein#PC00031;general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 MONDO|Ensembl=ENSMODG00000015175.3|UniProtKB=F7BWL0 F7BWL0 LECT2 PTHR11329:SF0 LEUKOCYTE CELL-DERIVED CHEMOTAXIN 2 LEUKOCYTE CELL-DERIVED CHEMOTAXIN-2 cytokine#PC00083;chemokine#PC00074 MONDO|Ensembl=ENSMODG00000024252.1|UniProtKB=F7AIJ2 F7AIJ2 CHRM5 PTHR24247:SF209 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M5 G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;acetylcholine receptor activity#GO:0015464;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;trans-synaptic signaling#GO:0099537;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896 plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell junction#GO:0030054;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 MONDO|Ensembl=ENSMODG00000025637.3|UniProtKB=A0A5F8G9D2 A0A5F8G9D2 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015560.3|UniProtKB=F7AJE3 F7AJE3 TRABD2A PTHR31120:SF7 METALLOPROTEASE TIKI METALLOPROTEASE TIKI1 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000006471.4|UniProtKB=F7FG90 F7FG90 GALNT3 PTHR11675:SF33 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 3 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000005896.4|UniProtKB=F6SLL2 F6SLL2 KLF10 PTHR23235:SF64 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 10 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017044.5|UniProtKB=F6XZS7 F6XZS7 RUSC1 PTHR15591:SF11 RUN AND SH3 DOMAIN CONTAINING AP-4 COMPLEX ACCESSORY SUBUNIT RUSC1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 MONDO|Ensembl=ENSMODG00000015599.3|UniProtKB=A0A5F8GR00 A0A5F8GR00 CAPG PTHR11977:SF127 VILLIN MACROPHAGE-CAPPING PROTEIN actin binding#GO:0003779;actin filament binding#GO:0051015;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;multicellular organismal process#GO:0032501;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;system development#GO:0048731;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of actin filament depolymerization#GO:0030834;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of protein-containing complex disassembly#GO:0043244;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;negative regulation of biological process#GO:0048519;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;cell projection organization#GO:0030030;central nervous system development#GO:0007417;regulation of cellular component organization#GO:0051128;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 FAS signaling pathway#P00020>Gelsolin#P00611 MONDO|Ensembl=ENSMODG00000015210.2|UniProtKB=F6V4K5 F6V4K5 DYNC1LI1 PTHR12688:SF2 DYNEIN LIGHT INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 LIGHT INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule-based movement#GO:0007018;cytoskeleton organization#GO:0007010 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;kinetochore#GO:0000776;dynein complex#GO:0030286;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;centrosome#GO:0005813;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;condensed chromosome, centromeric region#GO:0000779;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000016033.4|UniProtKB=F7BU73 F7BU73 HDLBP PTHR10627:SF34 SCP160 VIGILIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000020090.4|UniProtKB=F7ESQ8 F7ESQ8 LOC100010920 PTHR22589:SF53 CARNITINE O-ACYLTRANSFERASE CHOLINE_CARNITINE ACYLTRANSFERASE DOMAIN-CONTAINING PROTEIN palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000017615.4|UniProtKB=A0A5F8G4J2 A0A5F8G4J2 SAMD3 PTHR47302:SF1 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 3 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 3 MONDO|Ensembl=ENSMODG00000040173.1|UniProtKB=A0A5F8G8J3 A0A5F8G8J3 PTHR10666:SF424 UBIQUITIN UBIQUITIN-RIBOSOMAL PROTEIN EL40 FUSION PROTEIN structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;nucleus#GO:0005634;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000002046.4|UniProtKB=F6QC71 F6QC71 RORB PTHR45805:SF6 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR ROR-BETA sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulator activity#GO:0140110;transmembrane signaling receptor activity#GO:0004888;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;G protein-coupled receptor activity#GO:0004930;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000043809.1|UniProtKB=A0A5F8H880 A0A5F8H880 XNDC1N PTHR11370:SF4 DNA-REPAIR PROTEIN XRCC1 XRCC1 N-TERMINAL DOMAIN CONTAINING 1, N-TERMINAL LIKE nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000020747.3|UniProtKB=F6ZZZ4 F6ZZZ4 C4orf36 PTHR38002:SF1 C4ORF36 ISOFORM 11 CHROMOSOME 8 C4ORF36 HOMOLOG MONDO|Ensembl=ENSMODG00000005341.4|UniProtKB=F7CHS1 F7CHS1 APEX2 PTHR22748:SF4 AP ENDONUCLEASE DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE 2 hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;DNA endonuclease activity#GO:0004520;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;exonuclease activity#GO:0004527;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081;3'-5' exonuclease activity#GO:0008408;DNA exonuclease activity#GO:0004529 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000012929.3|UniProtKB=F7GC21 F7GC21 LOC100011572 PTHR43675:SF1 ARSENITE METHYLTRANSFERASE RIKEN CDNA 2700097O09 GENE transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000011736.4|UniProtKB=F7DFP1 F7DFP1 DUSP7 PTHR10159:SF305 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 7 hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000007108.5|UniProtKB=F7E374 F7E374 PIP4P1 PTHR21014:SF2 PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE TYPE 1 PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 4-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 dephosphorylation#GO:0016311;lipid modification#GO:0030258;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839 intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;cytoplasmic vesicle membrane#GO:0030659;phagocytic vesicle#GO:0045335;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;late endosome membrane#GO:0031902;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000036976.1|UniProtKB=A0A5F8GSJ6 A0A5F8GSJ6 PTHR10078:SF27 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-1 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;response to peptide#GO:1901652;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to lipopolysaccharide#GO:0032496;cell surface receptor signaling pathway#GO:0007166;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;inflammatory response#GO:0006954;response to bacterium#GO:0009617;cytokine-mediated signaling pathway#GO:0019221;biological regulation#GO:0065007;response to other organism#GO:0051707;immune response#GO:0006955;response to external stimulus#GO:0009605;defense response#GO:0006952;cellular response to molecule of bacterial origin#GO:0071219 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interleukin superfamily#PC00128;cytokine#PC00083;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000024454.2|UniProtKB=F6Z7Z8 F6Z7Z8 PTHR19339:SF0 T CELL RECEPTOR ALPHA VARIABLE 39 T CELL RECEPTOR ALPHA VARIABLE 41 MONDO|Ensembl=ENSMODG00000013407.4|UniProtKB=F7CNZ6 F7CNZ6 CDC42BPB PTHR22988:SF84 MYOTONIC DYSTROPHY S/T KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE MRCK BETA protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000012873.4|UniProtKB=A0A5F8HA09 A0A5F8HA09 DDX59 PTHR47958:SF30 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX59-RELATED isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000045708.1|UniProtKB=A0A5F8GR66 A0A5F8GR66 PTHR10844:SF16 CAVEOLIN CAVEOLIN-3 protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 monoatomic ion homeostasis#GO:0050801;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;developmental process#GO:0032502;regulation of membrane potential#GO:0042391;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular component organization#GO:0016043;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cytosolic calcium ion concentration#GO:0051480;membrane assembly#GO:0071709;cell differentiation#GO:0030154;homeostatic process#GO:0042592;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008 anchoring junction#GO:0070161;cell junction#GO:0030054;sarcolemma#GO:0042383;plasma membrane raft#GO:0044853;membrane microdomain#GO:0098857;cell-substrate junction#GO:0030055;plasma membrane#GO:0005886;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane raft#GO:0045121;membrane#GO:0016020;caveola#GO:0005901 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000008852.4|UniProtKB=F7CUM4 F7CUM4 SNUPN PTHR13403:SF6 SNURPORTIN1 RNUT1 PROTEIN RNA, U TRANSPORTER 1 SNURPORTIN-1 transporter#PC00227 MONDO|Ensembl=ENSMODG00000050482.1|UniProtKB=A0A5F8H5U5 A0A5F8H5U5 RASSF1 PTHR22738:SF12 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 1 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000009826.4|UniProtKB=F6WB80 F6WB80 RPP40 PTHR15396:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P40 RIBONUCLEASE P PROTEIN SUBUNIT P40 nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;ribonuclease P activity#GO:0004526;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460 ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;ribonuclease P complex#GO:0030677;catalytic complex#GO:1902494;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;multimeric ribonuclease P complex#GO:0030681;ribonuclease MRP complex#GO:0000172 RNA metabolism protein#PC00031;endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000008578.4|UniProtKB=F7CDD2 F7CDD2 PCNX4 PTHR12372:SF6 PECANEX PECANEX-LIKE PROTEIN 4 MONDO|Ensembl=ENSMODG00000020773.4|UniProtKB=F6Z9N3 F6Z9N3 MRPS18C PTHR13479:SF40 30S RIBOSOMAL PROTEIN S18 SMALL RIBOSOMAL SUBUNIT PROTEIN BS18M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000011765.4|UniProtKB=F7CW81 F7CW81 PSD2 PTHR10663:SF329 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 2 cell projection membrane#GO:0031253;ruffle#GO:0001726;ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000045268.1|UniProtKB=F7FQW0 F7FQW0 PTHR24242:SF197 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000405.4|UniProtKB=F6QMN3 F6QMN3 PI4K2B PTHR12865:SF6 PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-BETA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular component organization#GO:0016043;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;Golgi organization#GO:0007030;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;organelle organization#GO:0006996;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;endomembrane system organization#GO:0010256;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;vesicle organization#GO:0016050 Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000010874.4|UniProtKB=F7FW28 F7FW28 TRAPPC8 PTHR12975:SF6 TRANSPORT PROTEIN TRAPP TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 8 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;TRAPP complex#GO:0030008;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000002361.4|UniProtKB=A0A5F8H7A4 A0A5F8H7A4 HENMT1 PTHR21404:SF3 HEN1 SMALL RNA 2'-O-METHYLTRANSFERASE MONDO|Ensembl=ENSMODG00000028255.2|UniProtKB=K7DZS2 K7DZS2 SPMIP7 PTHR34759:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 48 PROTEIN SPMIP7 spermatogenesis#GO:0007283;developmental process#GO:0032502;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;gamete generation#GO:0007276;male gamete generation#GO:0048232 MONDO|Ensembl=ENSMODG00000004289.3|UniProtKB=F6SY20 F6SY20 RC3H1 PTHR13139:SF6 RING FINGER AND CCCH-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN ROQUIN-1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;RNA binding#GO:0003723;ubiquitin-like protein transferase activity#GO:0019787;double-stranded RNA binding#GO:0003725;ubiquitin protein ligase activity#GO:0061630;mRNA binding#GO:0003729;acyltransferase activity#GO:0016746;nucleic acid binding#GO:0003676;binding#GO:0005488 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;protein ubiquitination#GO:0016567;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;regulation of mRNA metabolic process#GO:1903311;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;protein catabolic process#GO:0030163;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;modification-dependent protein catabolic process#GO:0019941;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein modification process#GO:0036211;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000013928.4|UniProtKB=F6SUY0 F6SUY0 ATP4A PTHR43294:SF10 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 inorganic ion homeostasis#GO:0098771;localization#GO:0051179;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;export from cell#GO:0140352;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000010963.4|UniProtKB=F7BC55 F7BC55 SPPL2C PTHR12174:SF38 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 2C catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619 organelle subcompartment#GO:0031984;side of membrane#GO:0098552;intracellular organelle#GO:0043229;Golgi-associated vesicle membrane#GO:0030660;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;cytoplasmic side of membrane#GO:0098562;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;vacuole#GO:0005773;cytoplasmic vesicle membrane#GO:0030659;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;lysosomal membrane#GO:0005765;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;endoplasmic reticulum membrane#GO:0005789;Golgi-associated vesicle#GO:0005798;endomembrane system#GO:0012505;membrane#GO:0016020;vesicle membrane#GO:0012506 protein modifying enzyme#PC00260;aspartic protease#PC00053 MONDO|Ensembl=ENSMODG00000041874.1|UniProtKB=A0A5F8GDW2 A0A5F8GDW2 PTHR19229:SF274 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ABC-TYPE ORGANIC ANION TRANSPORTER ABCA8 ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;localization#GO:0051179;lipid transport#GO:0006869;macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000001846.4|UniProtKB=F6SNJ6 F6SNJ6 SYNGR2 PTHR10838:SF19 SYNAPTOGYRIN SYNAPTOGYRIN-2 LIKE PROTEIN-RELATED synaptic vesicle membrane organization#GO:0048499;cellular component organization#GO:0016043;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;export from cell#GO:0140352;regulated exocytosis#GO:0045055;transport#GO:0006810;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;secretion by cell#GO:0032940;exocytosis#GO:0006887 cell junction#GO:0030054;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;presynapse#GO:0098793;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000029155.2|UniProtKB=K7E4A3 K7E4A3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010390.3|UniProtKB=F7AUR7 F7AUR7 PDCD4 PTHR12626:SF3 PROGRAMMED CELL DEATH 4 PROGRAMMED CELL DEATH PROTEIN 4 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 translation factor#PC00223 MONDO|Ensembl=ENSMODG00000020020.3|UniProtKB=F7A800 F7A800 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028017.2|UniProtKB=K7E499 K7E499 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000037361.1|UniProtKB=K7DZ61 K7DZ61 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000008347.2|UniProtKB=A0A5F8GHF9 A0A5F8GHF9 STIM1 PTHR15136:SF9 STROMAL INTERACTION MOLECULE HOMOLOG STROMAL INTERACTION MOLECULE 1 molecular function regulator activity#GO:0098772;calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106;cation binding#GO:0043169;channel regulator activity#GO:0016247;metal ion binding#GO:0046872;transporter regulator activity#GO:0141108;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000013881.3|UniProtKB=F6W8G6 F6W8G6 PTHR16165:SF42 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 1 MONDO|Ensembl=ENSMODG00000038756.1|UniProtKB=A0A5F8G5M1 A0A5F8G5M1 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED RETROVIRAL ENVELOPE PROTEIN GP41-LIKE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000048458.1|UniProtKB=A0A5F8H9X9 A0A5F8H9X9 PTHR14024:SF11 PERILIPIN PERILIPIN-3 lipid storage#GO:0019915;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of localization#GO:0032879 cytosol#GO:0005829;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000015294.3|UniProtKB=F6QDL2 F6QDL2 C6orf47 PTHR14307:SF0 C6ORF47 FAMILY MEMBER SI:CH73-25F10.6 MONDO|Ensembl=ENSMODG00000040663.1|UniProtKB=A0A5F8HDD8 A0A5F8HDD8 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006227.4|UniProtKB=F6RPV0 F6RPV0 TMC5 PTHR23302:SF5 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 5 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;gated channel activity#GO:0022836;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000008956.2|UniProtKB=F7GCN7 F7GCN7 GPHB5 PTHR11515:SF14 GLYCOPROTEIN HORMONE BETA CHAIN GLYCOPROTEIN HORMONE BETA-5 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 MONDO|Ensembl=ENSMODG00000008848.4|UniProtKB=F7CUP0 F7CUP0 RHOU PTHR24072:SF148 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOU hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;protein binding#GO:0005515;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein kinase binding#GO:0019901;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cellular component organization#GO:0016043;signaling#GO:0023052;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;transport#GO:0006810;actin filament organization#GO:0007015;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein#PC00020;small GTPase#PC00208 Axon guidance mediated by netrin#P00009>cdc42#P00364;Cytoskeletal regulation by Rho GTPase#P00016>Cdc42#P00515 MONDO|Ensembl=ENSMODG00000007574.4|UniProtKB=F7CPX8 F7CPX8 FBXW10B PTHR19872:SF7 UBIQUITIN LIGASE SPECIFICITY FACTOR/HREP PROTEIN F-BOX DOMAIN-CONTAINING PROTEIN ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000016454.4|UniProtKB=F7A424 F7A424 RAE1 PTHR10971:SF11 MRNA EXPORT FACTOR AND BUB3 MRNA EXPORT FACTOR RAE1 RNA binding#GO:0003723;protein binding#GO:0005515;ubiquitin binding#GO:0043130;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular component organization#GO:0016043;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;nitrogen compound transport#GO:0071705;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000000325.4|UniProtKB=A0A5F8G8Z8 A0A5F8G8Z8 PTPN4 PTHR45706:SF7 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 4 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 cytoplasmic side of membrane#GO:0098562;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000016208.4|UniProtKB=A0A5F8G8V9 A0A5F8G8V9 PTHR24256:SF219 TRYPTASE-RELATED SERINE PROTEASE 33 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000020677.4|UniProtKB=F7DL81 F7DL81 TMEM165 PTHR12608:SF1 TRANSMEMBRANE PROTEIN HTP-1 RELATED DIVALENT CATION_PROTON ANTIPORTER TMEM165-RELATED calcium ion transmembrane transporter activity#GO:0015085;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transition metal ion transmembrane transporter activity#GO:0046915 metal ion transport#GO:0030001;homeostatic process#GO:0042592;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000049921.1|UniProtKB=A0A5F8GF87 A0A5F8GF87 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000006980.5|UniProtKB=A0A5F8HDS8 A0A5F8HDS8 GDF6 PTHR11848:SF43 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 6 cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to BMP#GO:0071772;developmental process#GO:0032502;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;multicellular organism development#GO:0007275;animal organ development#GO:0048513;signal transduction#GO:0007165;cellular process#GO:0009987;renal system development#GO:0072001;kidney development#GO:0001822;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000000663.4|UniProtKB=F6SBF4 F6SBF4 SLC45A4 PTHR19432:SF7 SUGAR TRANSPORTER POLYAMINE-TRANSPORTER SLC45A4 monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;solute:proton symporter activity#GO:0015295;symporter activity#GO:0015293;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000003641.4|UniProtKB=A0A5F8G2F9 A0A5F8G2F9 CPNE6 PTHR10857:SF5 COPINE COPINE-6 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 response to metal ion#GO:0010038;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;response to calcium ion#GO:0051592;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000009971.3|UniProtKB=F6Y7V7 F6Y7V7 CXCL12 PTHR12015:SF193 SMALL INDUCIBLE CYTOKINE A STROMAL CELL-DERIVED FACTOR 1 cytokine#PC00083 Axon guidance mediated by Slit/Robo#P00008>Sdf1#P00346 MONDO|Ensembl=ENSMODG00000015407.4|UniProtKB=F6T468 F6T468 PLCD4 PTHR10336:SF31 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA-4 glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;lipase activity#GO:0016298;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 MONDO|Gene=SPA17|UniProtKB=O62771 O62771 SPA17 PTHR10699:SF16 NEUROMODULIN SPERM SURFACE PROTEIN SP17 protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 sperm principal piece#GO:0097228;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;cilium#GO:0005929;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000013350.4|UniProtKB=A0A5F8H1W1 A0A5F8H1W1 RCOR1 PTHR16089:SF11 REST COREPRESSOR COREST PROTEIN-RELATED REST COREPRESSOR 1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000048217.1|UniProtKB=A0A5F8H857 A0A5F8H857 PTHR24381:SF487 ZINC FINGER PROTEIN MHCY REGION ZINC FINGER PROTEIN 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000020937.3|UniProtKB=H9H7T2 H9H7T2 PTHR45616:SF52 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CUTICULAR HB3 structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;epidermis development#GO:0008544;developmental process#GO:0032502;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;epithelium development#GO:0060429;skin development#GO:0043588;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000012709.2|UniProtKB=F6UY50 F6UY50 UQCRFS1 PTHR10134:SF50 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060 catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex III#GO:0045275;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000001021.4|UniProtKB=A0A5F8GPI5 A0A5F8GPI5 FHIP1A PTHR21705:SF6 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK-INTERACTING PROTEIN 1A MONDO|Ensembl=ENSMODG00000037837.1|UniProtKB=A0A5F8GVD6 A0A5F8GVD6 TMEM19 PTHR13353:SF5 TRANSMEMBRANE PROTEIN 19 TRANSMEMBRANE PROTEIN 19 membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000027683.2|UniProtKB=K7DZM4 K7DZM4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009920.4|UniProtKB=F6R9A7 F6R9A7 SH2D4A PTHR14388:SF5 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 4A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000014030.3|UniProtKB=F6V8I8 F6V8I8 PTHR24248:SF176 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 101-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000047610.1|UniProtKB=A0A5F8GIS9 A0A5F8GIS9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000002217.3|UniProtKB=F7DG26 F7DG26 PEX13 PTHR19332:SF1 PEROXISOMAL MEMBRANE PROTEIN PEX13 PEROXISOMAL MEMBRANE PROTEIN PEX13 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein import into peroxisome matrix#GO:0016558;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein transport#GO:0015031;peroxisomal transport#GO:0043574;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;peroxisome organization#GO:0007031 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peroxisomal membrane#GO:0005778;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;transporter complex#GO:1990351;intracellular organelle#GO:0043229 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000024705.3|UniProtKB=F7CB39 F7CB39 PIEZO2 PTHR13167:SF24 PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 biological regulation#GO:0065007;response to stimulus#GO:0050896;cellular response to environmental stimulus#GO:0104004;response to mechanical stimulus#GO:0009612;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;response to external stimulus#GO:0009605;regulation of biological quality#GO:0065008;cellular response to abiotic stimulus#GO:0071214;regulation of membrane potential#GO:0042391;detection of mechanical stimulus#GO:0050982 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000003328.4|UniProtKB=A0A5F8GDQ1 A0A5F8GDQ1 OAS3 PTHR11258:SF4 2-5 OLIGOADENYLATE SYNTHETASE 2'-5'-OLIGOADENYLATE SYNTHASE 3 binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;adenylyltransferase activity#GO:0070566;RNA binding#GO:0003723;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 cell communication#GO:0007154;response to virus#GO:0009615;cytokine-mediated signaling pathway#GO:0019221;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;antiviral innate immune response#GO:0140374;cellular response to stimulus#GO:0051716;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;biological regulation#GO:0065007;response to other organism#GO:0051707;immune response#GO:0006955;response to peptide#GO:1901652;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 nucleus#GO:0005634;cytosol#GO:0005829;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;nucleotidyltransferase#PC00174 MONDO|Ensembl=ENSMODG00000049094.1|UniProtKB=A0A5F8GDA7 A0A5F8GDA7 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000041711.1|UniProtKB=A0A5F8GF39 A0A5F8GF39 C1orf116 PTHR21555:SF0 SPECIFICALLY ANDROGEN-REGULATED GENE PROTEIN SPECIFICALLY ANDROGEN-REGULATED GENE PROTEIN hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to steroid hormone#GO:0048545;cellular response to chemical stimulus#GO:0070887;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;intracellular receptor signaling pathway#GO:0030522;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;steroid hormone receptor signaling pathway#GO:0043401;regulation of biological process#GO:0050789;cellular response to steroid hormone stimulus#GO:0071383;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;nuclear receptor-mediated signaling pathway#GO:0141193;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000004085.3|UniProtKB=A0A5F8H616 A0A5F8H616 LTO1 PTHR28532:SF1 GEO13458P1 LTO1 MATURATION FACTOR OF ABCE1 MONDO|Ensembl=ENSMODG00000007224.4|UniProtKB=F6WCR8 F6WCR8 SOX6 PTHR45789:SF1 FI18025P1 TRANSCRIPTION FACTOR SOX-6 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000002449.3|UniProtKB=F7DF53 F7DF53 EIF1B PTHR10388:SF51 EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 EUKARYOTIC TRANSLATION INITIATION FACTOR 1B translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;nucleic acid binding#GO:0003676;binding#GO:0005488 ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000002372.4|UniProtKB=A0A5F8GPG3 A0A5F8GPG3 ENDOV PTHR28511:SF1 ENDONUCLEASE V ENDONUCLEASE V nucleic acid binding#GO:0003676;binding#GO:0005488;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;single-stranded RNA binding#GO:0003727 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000007244.3|UniProtKB=F6WBQ4 F6WBQ4 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037158.1|UniProtKB=K7E3W4 K7E3W4 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000038153.1|UniProtKB=A0A5F8GJH1 A0A5F8GJH1 GABRD PTHR18945:SF34 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT DELTA transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;chloride channel activity#GO:0005254;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;monoatomic anion channel activity#GO:0005253;ligand-gated monoatomic ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108 establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;synaptic signaling#GO:0099536;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;cell communication#GO:0007154;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;trans-synaptic signaling#GO:0099537;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268 signaling receptor complex#GO:0043235;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;GABA-ergic synapse#GO:0098982;protein-containing complex#GO:0032991;synapse#GO:0045202;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000020028.2|UniProtKB=F7A7E1 F7A7E1 LOC100022828 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000049847.1|UniProtKB=A0A5F8GYR4 A0A5F8GYR4 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000019288.4|UniProtKB=F6RZV1 F6RZV1 GIN1 PTHR47266:SF6 ENDONUCLEASE-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 MONDO|Ensembl=ENSMODG00000017625.4|UniProtKB=F6ZT25 F6ZT25 EGLN3 PTHR12907:SF28 EGL NINE HOMOLOG-RELATED PROLYL HYDROXYLASE EGLN3 metal ion binding#GO:0046872;dioxygenase activity#GO:0051213;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;iron ion binding#GO:0005506;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;ferrous iron binding#GO:0008198;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;regulation of programmed cell death#GO:0043067;cellular response to hypoxia#GO:0071456;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;response to hypoxia#GO:0001666 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 Hypoxia response via HIF activation#P00030>Prolyl Hydroxylase#P00821 MONDO|Ensembl=ENSMODG00000010329.2|UniProtKB=F6S9H8 F6S9H8 ADRA2A PTHR24248:SF24 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-2A ADRENERGIC RECEPTOR cation binding#GO:0043169;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;G protein-coupled amine receptor activity#GO:0008227;hormone binding#GO:0042562 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 MONDO|Ensembl=ENSMODG00000016774.4|UniProtKB=F7GG55 F7GG55 GATA5 PTHR10071:SF289 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANSCRIPTION FACTOR GATA-5 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;muscle tissue development#GO:0060537;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;tissue development#GO:0009888;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;cardiac muscle tissue development#GO:0048738;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;heart development#GO:0007507;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;striated muscle tissue development#GO:0014706;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;animal organ development#GO:0048513 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000018381.3|UniProtKB=A0A5F8H3H4 A0A5F8H3H4 PRSS35 PTHR15462:SF17 SERINE PROTEASE INACTIVE SERINE PROTEASE 35 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000017706.3|UniProtKB=F7FUR3 F7FUR3 PTHR24390:SF290 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 184 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000019685.4|UniProtKB=F6TD14 F6TD14 PIK3R1 PTHR10155:SF3 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 response to nitrogen compound#GO:1901698;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to oxygen-containing compound#GO:1901700;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;insulin receptor signaling pathway#GO:0008286;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;cellular response to peptide hormone stimulus#GO:0071375;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;response to endogenous stimulus#GO:0009719;cell surface receptor signaling pathway#GO:0007166;cellular response to insulin stimulus#GO:0032869;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725 transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898;membrane protein complex#GO:0098796;membrane#GO:0016020;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 kinase modulator#PC00140 CCKR signaling map#P06959>p85#P07212;T cell activation#P00053>PI3K#P01322;p53 pathway feedback loops 2#P04398>PI3K#P04661;Integrin signalling pathway#P00034>PI3K#P00936;VEGF signaling pathway#P00056>PI3K#P01413;Gonadotropin-releasing hormone receptor pathway#P06664>PI3K#P06766;Axon guidance mediated by netrin#P00009>PI3K#P00363;Angiogenesis#P00005>PI3K#P00236;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;PI3 kinase pathway#P00048>p85#P01202;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;PDGF signaling pathway#P00047>PI3K#P01168 MONDO|Ensembl=ENSMODG00000002590.4|UniProtKB=F7G517 F7G517 TECR PTHR10556:SF31 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE VERY-LONG-CHAIN ENOYL-COA REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 cellular process#GO:0009987;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000003883.3|UniProtKB=A0A5F8GPH7 A0A5F8GPH7 CRLS1 PTHR14269:SF60 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED CARDIOLIPIN SYNTHASE (CMP-FORMING) transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity#GO:0016740;catalytic activity#GO:0003824 organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;phosphatidylglycerol metabolic process#GO:0046471;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;phosphatidylglycerol biosynthetic process#GO:0006655;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000008022.4|UniProtKB=A0A5F8G2W9 A0A5F8G2W9 KLHL41 PTHR21351:SF0 BARDET-BIEDL SYNDROME PROTEIN 5 BBSOME COMPLEX MEMBER BBS5 phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;BBSome#GO:0034464;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000008855.4|UniProtKB=F7CUJ1 F7CUJ1 CYP7A1 PTHR24304:SF1 CYTOCHROME P450 FAMILY 7 CYTOCHROME P450 7A1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;cellular process#GO:0009987;cholesterol homeostasis#GO:0042632;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;small molecule metabolic process#GO:0044281;homeostatic process#GO:0042592;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000037106.1|UniProtKB=A0A5F8GD38 A0A5F8GD38 PTHR13025:SF5 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN-CONTAINING PROTEIN D1 calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000020435.3|UniProtKB=F7AR66 F7AR66 PTHR47091:SF2 ALPHA-PROTEIN KINASE 2-RELATED ALPHA-PROTEIN KINASE 2 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000002308.4|UniProtKB=F6YDR8 F6YDR8 PTHR19325:SF545 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING COMPLEMENT RECEPTOR TYPE 1 immune response#GO:0006955;negative regulation of response to stimulus#GO:0048585;adaptive immune response#GO:0002250;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;negative regulation of biological process#GO:0048519;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of immune response#GO:0050776;T cell mediated immunity#GO:0002456;negative regulation of immune response#GO:0050777;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;regulation of immune effector process#GO:0002697;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 complement component#PC00078;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000001303.4|UniProtKB=F7BZM9 F7BZM9 LOC103104271 PTHR10709:SF11 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 1A cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cortical actin cytoskeleton organization#GO:0030866;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 Huntington disease#P00029>Arp2/3 complex#P00811;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 MONDO|Ensembl=ENSMODG00000012598.5|UniProtKB=F6PI81 F6PI81 MLLT6 PTHR13793:SF90 PHD FINGER PROTEINS PROTEIN AF-17 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000006217.3|UniProtKB=F7FSA4 F7FSA4 PTHR48001:SF124 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1M1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004994.4|UniProtKB=F7F7E6 F7F7E6 THOP1 PTHR11804:SF50 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED THIMET OLIGOPEPTIDASE endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000043984.1|UniProtKB=A0A5F8GXC7 A0A5F8GXC7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000020191.3|UniProtKB=F7G8C3 F7G8C3 OR4D6 PTHR48002:SF23 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D6 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024822.2|UniProtKB=F7AB25 F7AB25 PTHR21668:SF6 EIF-1A EUKARYOTIC TRANSLATION INITIATION FACTOR 1A, X-CHROMOSOMAL translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000045038.1|UniProtKB=A0A5F8GT98 A0A5F8GT98 PTHR33426:SF45 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IMMUNODEFICIENCY LENTIVIRAL MATRIX N-TERMINAL DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000012142.4|UniProtKB=A0A5F8H8J6 A0A5F8H8J6 KAT7 PTHR10615:SF222 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT7 N-acetyltransferase activity#GO:0008080;chromatin binding#GO:0003682;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;histone acetyltransferase activity#GO:0004402;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;transcription regulator activity#GO:0140110;binding#GO:0005488;acetyltransferase activity#GO:0016407;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;protein N-acetyltransferase activity#GO:0034212 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 Alzheimer disease-presenilin pathway#P00004>Tip60#P00137 MONDO|Ensembl=ENSMODG00000010985.4|UniProtKB=F7APG4 F7APG4 SLK PTHR48012:SF11 STERILE20-LIKE KINASE, ISOFORM B-RELATED STE20-LIKE SERINE_THREONINE-PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;regulation of cell motility#GO:2000145;intracellular signal transduction#GO:0035556;regulation of apoptotic process#GO:0042981;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of locomotion#GO:0040012;signaling#GO:0023052;biological regulation#GO:0065007;regulation of programmed cell death#GO:0043067;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000047582.1|UniProtKB=A0A5F8GSS6 A0A5F8GSS6 CXCL13 PTHR12015:SF198 SMALL INDUCIBLE CYTOKINE A INTERLEUKIN-8 protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664 response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;biological process involved in interspecies interaction between organisms#GO:0044419;response to molecule of bacterial origin#GO:0002237;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;neutrophil migration#GO:1990266;taxis#GO:0042330;response to chemical#GO:0042221;granulocyte migration#GO:0097530;cellular response to lipid#GO:0071396;defense response to other organism#GO:0098542;response to lipid#GO:0033993;response to biotic stimulus#GO:0009607;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;defense response to symbiont#GO:0140546;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;neutrophil chemotaxis#GO:0030593;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;cell motility#GO:0048870;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326;response to bacterium#GO:0009617;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cell migration#GO:0016477;response to other organism#GO:0051707;immune response#GO:0006955;cellular response to molecule of bacterial origin#GO:0071219;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;leukocyte migration#GO:0050900 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 CCKR signaling map#P06959>IL8#G07296;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856;CCKR signaling map#P06959>IL8#G07001;CCKR signaling map#P06959>IL8#P07136;Interleukin signaling pathway#P00036>Interleukin#P00970 MONDO|Ensembl=ENSMODG00000008603.4|UniProtKB=F6PHE0 F6PHE0 GAL3ST2 PTHR14647:SF55 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSE-3-O-SULFOTRANSFERASE 2 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 transferase#PC00220 MONDO|Ensembl=ENSMODG00000018377.4|UniProtKB=F6QVT1 F6QVT1 SNX4 PTHR46596:SF1 SORTING NEXIN-4 SORTING NEXIN-4 phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488;phospholipid binding#GO:0005543 transport#GO:0006810;establishment of localization#GO:0051234;positive regulation of catabolic process#GO:0009896;intracellular protein localization#GO:0008104;regulation of macroautophagy#GO:0016241;regulation of catabolic process#GO:0009894;positive regulation of autophagy#GO:0010508;macromolecule localization#GO:0033036;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;regulation of organelle assembly#GO:1902115;establishment of protein localization#GO:0045184;positive regulation of cellular process#GO:0048522;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of autophagosome assembly#GO:2000785;positive regulation of cellular component organization#GO:0051130;localization#GO:0051179;positive regulation of metabolic process#GO:0009893;positive regulation of organelle organization#GO:0010638;protein transport#GO:0015031;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;positive regulation of macroautophagy#GO:0016239;regulation of cellular component biogenesis#GO:0044087 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005464.4|UniProtKB=F7CGB6 F7CGB6 ACAD8 PTHR43831:SF1 ISOBUTYRYL-COA DEHYDROGENASE ISOBUTYRYL-COA DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000008092.4|UniProtKB=F7GFV6 F7GFV6 ZMYM2 PTHR45736:SF6 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 2 zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000012904.4|UniProtKB=A0A5F8H9C0 A0A5F8H9C0 VRK1 PTHR11909:SF78 CASEIN KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE VRK1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;response to stress#GO:0006950;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000040047.1|UniProtKB=A0A5F8GAS1 A0A5F8GAS1 PLAGL2 PTHR24390:SF173 ZINC FINGER PROTEIN PLAG1 LIKE ZINC FINGER 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000008261.4|UniProtKB=F6Z8P2 F6Z8P2 PELI3 PTHR12098:SF9 E3 UBIQUITIN-PROTEIN LIGASE PELLINO-RELATED E3 UBIQUITIN-PROTEIN LIGASE PELLINO HOMOLOG 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein K63-linked ubiquitination#GO:0070534;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000016357.3|UniProtKB=F7F6V0 F7F6V0 DNAJA3 PTHR44145:SF6 DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000013446.4|UniProtKB=F7G9L6 F7G9L6 YEATS2 PTHR23195:SF7 YEATS DOMAIN YEATS DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338 protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;SAGA-type complex#GO:0070461;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000045104.1|UniProtKB=A0A5F8GR15 A0A5F8GR15 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012279.2|UniProtKB=F6YFY5 F6YFY5 GNAT1 PTHR10218:SF67 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-1 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 signal transduction#GO:0007165;cellular process#GO:0009987;response to radiation#GO:0009314;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;system process#GO:0003008;response to external stimulus#GO:0009605;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;sensory perception of light stimulus#GO:0050953;signaling#GO:0023052;visual perception#GO:0007601;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;side of membrane#GO:0098552;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cilium#GO:0005929;catalytic complex#GO:1902494;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796 heterotrimeric G-protein#PC00117;G-protein#PC00020 Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Opioid proenkephalin pathway#P05915>G-protein#P05994;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;PI3 kinase pathway#P00048>Galpha#P01199;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gtalpha#P00760;Enkephalin release#P05913>G-Protein (i)#P05974 MONDO|Ensembl=ENSMODG00000008546.4|UniProtKB=F7DGY8 F7DGY8 PTHR14562:SF3 TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT D TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT D intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000045299.1|UniProtKB=A0A5F8GWS0 A0A5F8GWS0 CREG1 PTHR13343:SF21 CREG1 PROTEIN PROTEIN CREG1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000028382.2|UniProtKB=K7E107 K7E107 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016711.4|UniProtKB=F7D1S5 F7D1S5 KCTD9 PTHR14136:SF17 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 MONDO|Ensembl=ENSMODG00000014238.3|UniProtKB=F6T927 F6T927 TDRP PTHR35663:SF1 TESTIS DEVELOPMENT-RELATED PROTEIN-RELATED TESTIS DEVELOPMENT-RELATED PROTEIN multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;developmental process#GO:0032502;spermatogenesis#GO:0007283;gamete generation#GO:0007276;male gamete generation#GO:0048232;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000007844.2|UniProtKB=F7ET94 F7ET94 PTHR48002:SF59 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4L1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000039204.1|UniProtKB=F7EVQ1 F7EVQ1 LOC100028856 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000039657.1|UniProtKB=A0A5F8GZL1 A0A5F8GZL1 PTHR12669:SF14 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1 binding#GO:0005488;translation regulator activity#GO:0045182;protein binding#GO:0005515;translation initiation factor binding#GO:0031369 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of translation#GO:0017148;regulation of translational initiation#GO:0006446;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 translation initiation factor#PC00224;translation factor#PC00223 p53 pathway by glucose deprivation#P04397>4E-BP1#P04637;p38 MAPK pathway#P05918>4E-BP1#P06042;CCKR signaling map#P06959>4E-BP1#P07230 MONDO|Ensembl=ENSMODG00000013741.4|UniProtKB=F6X875 F6X875 MMP9 PTHR10201:SF30 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-9 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 catabolic process#GO:0009056;cellular process#GO:0009987;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Plasminogen activating cascade#P00050>pro-MMP-9#P01259;CCKR signaling map#P06959>MMP9#G06994;CCKR signaling map#P06959>MMP9#G07288;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 MONDO|Ensembl=ENSMODG00000047935.1|UniProtKB=A0A5F8GWN1 A0A5F8GWN1 PTHR23304:SF189 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000005688.4|UniProtKB=A0A5F8GCJ1 A0A5F8GCJ1 EEIG1 PTHR21456:SF2 FAMILY WITH SEQUENCE SIMILARITY 102 EARLY ESTROGEN-INDUCED GENE 1 PROTEIN MONDO|Ensembl=ENSMODG00000000304.3|UniProtKB=F6WA61 F6WA61 LOC100012635 PTHR10010:SF23 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;phosphate transmembrane transporter activity#GO:0005315;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370 homeostatic process#GO:0042592;phosphate ion transport#GO:0006817;intracellular chemical homeostasis#GO:0055082;inorganic anion transport#GO:0015698;cellular homeostasis#GO:0019725;localization#GO:0051179;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;organelle#GO:0043226;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;brush border#GO:0005903;cell periphery#GO:0071944;vesicle#GO:0031982;cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;apical part of cell#GO:0045177 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000016041.4|UniProtKB=F6YUL8 F6YUL8 SEPTIN2 PTHR18884:SF67 SEPTIN SEPTIN-2 hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 plasma membrane bounded cell projection assembly#GO:0120031;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;cytokinesis#GO:0000910;cilium organization#GO:0044782;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;cell cycle process#GO:0022402;cell division#GO:0051301;cell cycle#GO:0007049;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell periphery#GO:0071944;cell cortex#GO:0005938;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 MONDO|Ensembl=ENSMODG00000023648.3|UniProtKB=F6YU87 F6YU87 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025284.2|UniProtKB=F7A2K9 F7A2K9 TMEM125 PTHR31416:SF1 TRANSMEMBRANE PROTEIN 125 TRANSMEMBRANE PROTEIN 125 MONDO|Ensembl=ENSMODG00000019837.4|UniProtKB=F6SAI1 F6SAI1 TRAF6 PTHR10131:SF152 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 6 molecular adaptor activity#GO:0060090;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;signaling adaptor activity#GO:0035591 regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;defense response#GO:0006952;cellular response to molecule of bacterial origin#GO:0071219;innate immune response#GO:0045087;immune response#GO:0006955;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to other organism#GO:0051707;response to bacterium#GO:0009617;lipopolysaccharide-mediated signaling pathway#GO:0031663;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;defense response to other organism#GO:0098542;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;cell junction#GO:0030054;side of membrane#GO:0098552 scaffold/adaptor protein#PC00226 p38 MAPK pathway#P05918>TRAF6#P06038;p53 pathway#P00059>TRAF#P04620;Apoptosis signaling pathway#P00006>TRAF2#P00306;Toll receptor signaling pathway#P00054>TRAF6#P01371 MONDO|Ensembl=ENSMODG00000002825.4|UniProtKB=F7EJ31 F7EJ31 WFS1 PTHR13098:SF3 WOLFRAMIN WOLFRAMIN monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;endoplasmic reticulum unfolded protein response#GO:0030968;monoatomic ion homeostasis#GO:0050801;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;calcium ion homeostasis#GO:0055074;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to stress#GO:0033554;inorganic ion homeostasis#GO:0098771;cellular response to topologically incorrect protein#GO:0035967;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;homeostatic process#GO:0042592 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000050948.1|UniProtKB=A0A5F8HEE8 A0A5F8HEE8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000048659.1|UniProtKB=A0A5F8GKU4 A0A5F8GKU4 PTHR11571:SF282 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE-RELATED glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;glutathione metabolic process#GO:0006749 transferase#PC00220 MONDO|Ensembl=ENSMODG00000046795.1|UniProtKB=A0A5F8GSZ6 A0A5F8GSZ6 PTHR22674:SF4 NTPASE, KAP FAMILY P-LOOP DOMAIN-CONTAINING 1 NTPASE KAP FAMILY P-LOOP DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000000567.4|UniProtKB=F6X4G0 F6X4G0 CFAP300 PTHR31078:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 300 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 300 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000003440.5|UniProtKB=F7DX14 F7DX14 SPIRE2 PTHR21345:SF5 SPIRE PROTEIN SPIRE HOMOLOG 2 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 organelle localization#GO:0051640;actin filament-based process#GO:0030029;sexual reproduction#GO:0019953;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;multicellular organismal reproductive process#GO:0048609;supramolecular fiber organization#GO:0097435;cell cycle#GO:0007049;cell division#GO:0051301;actin cytoskeleton organization#GO:0030036;reproductive process#GO:0022414;intracellular transport#GO:0046907;transport#GO:0006810;meiotic nuclear division#GO:0140013;establishment of localization#GO:0051234;actin filament organization#GO:0007015;establishment of spindle localization#GO:0051293;membrane organization#GO:0061024;cytokinesis#GO:0000910;nuclear division#GO:0000280;cytokinetic process#GO:0032506;cellular localization#GO:0051641;spindle localization#GO:0051653;cytoskeleton-dependent cytokinesis#GO:0061640;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;gamete generation#GO:0007276;establishment of organelle localization#GO:0051656;meiotic cell cycle#GO:0051321;Golgi vesicle transport#GO:0048193;membrane invagination#GO:0010324;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytoskeleton organization#GO:0007010 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;cell cortex#GO:0005938;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000042939.1|UniProtKB=K7E4B6 K7E4B6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013946.4|UniProtKB=F6SBT0 F6SBT0 TGM3 PTHR11590:SF36 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE E catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;epithelium development#GO:0060429;cell differentiation#GO:0030154;skin development#GO:0043588;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;epidermis development#GO:0008544;developmental process#GO:0032502;cellular developmental process#GO:0048869;animal organ development#GO:0048513;anatomical structure development#GO:0048856 transferase#PC00220 MONDO|Ensembl=ENSMODG00000045709.1|UniProtKB=H9H885 H9H885 monDomV1R1239 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000050770.1|UniProtKB=A0A5F8GCY1 A0A5F8GCY1 LOC100619254 PTHR23226:SF430 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 1010-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000021060.5|UniProtKB=F6VIV5 F6VIV5 DONSON PTHR12972:SF0 DOWNSTREAM NEIGHBOR OF SON PROTEIN DOWNSTREAM NEIGHBOR OF SON nucleobase-containing compound metabolic process#GO:0006139;DNA replication#GO:0006260;cellular process#GO:0009987;cell cycle process#GO:0022402;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA metabolic process#GO:0006259;nuclear DNA replication#GO:0033260;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000025366.3|UniProtKB=A0A5F8H0Q8 A0A5F8H0Q8 PDE9A PTHR11347:SF236 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 9A cyclic-nucleotide phosphodiesterase activity#GO:0004112;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;nucleotide metabolic process#GO:0009117;regulation of signaling#GO:0023051;ribonucleotide metabolic process#GO:0009259;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;cyclic purine nucleotide metabolic process#GO:0052652;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;regulation of response to stimulus#GO:0048583;cyclic nucleotide metabolic process#GO:0009187;negative regulation of cellular process#GO:0048523;nucleotide catabolic process#GO:0009166 phosphodiesterase#PC00185;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000002005.4|UniProtKB=A0A5F8GD15 A0A5F8GD15 EFEMP1 PTHR24039:SF33 FIBRILLIN-RELATED EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 1 extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000010883.4|UniProtKB=F7FVX7 F7FVX7 PTHR23235:SF46 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 8 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000028018.2|UniProtKB=K7E0B2 K7E0B2 PTHR31954:SF2 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cilium assembly#GO:0060271;cellular component organization#GO:0016043;sperm motility#GO:0097722;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;microtubule-based process#GO:0007017;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;organelle assembly#GO:0070925;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000016866.3|UniProtKB=F6Y243 F6Y243 PTHR22803:SF116 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED REGENERATING ISLET-DERIVED PROTEIN 3-GAMMA signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179 humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to hormone#GO:0009725;response to biotic stimulus#GO:0009607;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;response to other organism#GO:0051707;biological regulation#GO:0065007;immune system process#GO:0002376;response to oxygen-containing compound#GO:1901700;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;regulation of cell population proliferation#GO:0042127;response to nitrogen compound#GO:1901698;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000037689.1|UniProtKB=A0A5F8G1V1 A0A5F8G1V1 PTHR46427:SF1 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 1 STRUCTURE-SPECIFIC ENDONUCLEASE ANKLE1 DNA endonuclease activity#GO:0004520;catalytic activity, acting on DNA#GO:0140097;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536 nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA recombination#GO:0006310;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;organelle fission#GO:0048285;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;reproductive process#GO:0022414;homologous recombination#GO:0035825;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;resolution of meiotic recombination intermediates#GO:0000712 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000043355.1|UniProtKB=A0A5F8GDC5 A0A5F8GDC5 LOC130458129 PTHR23428:SF386 HISTONE H2B HISTONE H2B 1-RELATED chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000016766.4|UniProtKB=F7GGJ4 F7GGJ4 USP6NL PTHR22957:SF193 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN USP6 N-TERMINAL-LIKE PROTEIN enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cellular process#GO:0009987;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000013019.4|UniProtKB=F7BP50 F7BP50 HEATR3 PTHR13347:SF1 HEAT REPEAT-CONTAINING PROTEIN 3 HEAT REPEAT-CONTAINING PROTEIN 3 intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;protein localization to organelle#GO:0033365;ribonucleoprotein complex biogenesis#GO:0022613 MONDO|Ensembl=ENSMODG00000021273.3|UniProtKB=F6T2H6 F6T2H6 PTHR13544:SF0 SELENOPROTEIN T THIOREDOXIN REDUCTASE-LIKE SELENOPROTEIN T antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000023931.2|UniProtKB=F7FLC9 F7FLC9 PTHR11620:SF106 60S RIBOSOMAL PROTEIN L23A LARGE RIBOSOMAL SUBUNIT PROTEIN UL23 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000016072.4|UniProtKB=F7G9S6 F7G9S6 LOC100026235 PTHR24257:SF22 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 3B catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000012390.5|UniProtKB=F6PNB5 F6PNB5 TSHZ3 PTHR12487:SF5 TEASHIRT-RELATED TEASHIRT HOMOLOG 3 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of system process#GO:0044057;regulation of biosynthetic process#GO:0009889;system process#GO:0003008;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;nervous system process#GO:0050877;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000018037.3|UniProtKB=F7GES5 F7GES5 monDomV1R1283 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015255.4|UniProtKB=F6U3V1 F6U3V1 GASK1A PTHR15905:SF5 GOLGI-ASSOCIATED KINASE 1B-RELATED GOLGI-ASSOCIATED KINASE 1A organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000008799.2|UniProtKB=F6QVF8 F6QVF8 LOC100011081 PTHR26453:SF112 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2B11 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002977.4|UniProtKB=F6Q552 F6Q552 NECAB3 PTHR12178:SF3 EF-HAND DOMAIN-CONTAINING PROTEIN N-TERMINAL EF-HAND CALCIUM-BINDING PROTEIN 3 regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi cis cisterna#GO:0000137;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;Golgi cisterna#GO:0031985;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000018641.4|UniProtKB=A0A5F8GFJ5 A0A5F8GFJ5 PTHR12687:SF4 NUCLEOLAR COMPLEX 2 AND RAD4-RELATED NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;cellular process#GO:0009987 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687 MONDO|Ensembl=ENSMODG00000015062.3|UniProtKB=F7FHQ3 F7FHQ3 CMC1 PTHR22977:SF5 COX ASSEMBLY MITOCHONDRIAL PROTEIN COX ASSEMBLY MITOCHONDRIAL PROTEIN HOMOLOG intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000012531.4|UniProtKB=A0A5F8H890 A0A5F8H890 SERPINA7 PTHR11461:SF375 SERINE PROTEASE INHIBITOR, SERPIN THYROXINE-BINDING GLOBULIN peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000041139.1|UniProtKB=A0A5F8H7A5 A0A5F8H7A5 GSTP1 PTHR11571:SF141 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE P catalytic activity#GO:0003824;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220 MONDO|Ensembl=ENSMODG00000022893.2|UniProtKB=F6Q1M1 F6Q1M1 PTHR26450:SF83 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52P1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013734.4|UniProtKB=F6XQG8 F6XQG8 HPN PTHR24253:SF166 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE HEPSIN hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000000596.4|UniProtKB=A0A5F8GPS3 A0A5F8GPS3 TTLL7 PTHR12241:SF147 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL7 catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 intracellular organelle#GO:0043229;cilium#GO:0005929;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000000352.3|UniProtKB=F6RUC5 F6RUC5 PTHR24369:SF161 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 53 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000015821.4|UniProtKB=F7FDY9 F7FDY9 RAB10 PTHR47980:SF87 LD44762P RAS-RELATED PROTEIN RAB-10 endocytic recycling#GO:0032456;export from cell#GO:0140352;localization within membrane#GO:0051668;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;secretion by cell#GO:0032940;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;exocytosis#GO:0006887;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;endomembrane system#GO:0012505;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000008032.3|UniProtKB=A0A5F8GC71 A0A5F8GC71 LOC100015543 PTHR10517:SF14 FOLATE RECEPTOR FOLATE RECEPTOR 1-RELATED signaling receptor activity#GO:0038023;cargo receptor activity#GO:0038024;molecular transducer activity#GO:0060089 vitamin transport#GO:0051180;dicarboxylic acid transport#GO:0006835;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;localization#GO:0051179;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000039771.1|UniProtKB=A0A5F8HJN3 A0A5F8HJN3 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004059.4|UniProtKB=A0A5F8G4P3 A0A5F8G4P3 CDH10 PTHR24027:SF290 CADHERIN-23 CADHERIN-10 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 anatomical structure morphogenesis#GO:0009653;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cell adhesion#GO:0007155;synapse organization#GO:0050808;synaptic membrane adhesion#GO:0099560;anatomical structure development#GO:0048856;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular component assembly#GO:0022607;cell migration#GO:0016477;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840 membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;anchoring junction#GO:0070161 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000029177.2|UniProtKB=K7E1J2 K7E1J2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000015797.4|UniProtKB=F7FS23 F7FS23 DRC1 PTHR21625:SF1 NYD-SP28 PROTEIN DYNEIN REGULATORY COMPLEX PROTEIN 1 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;regulation of microtubule-based process#GO:0032886;cilium or flagellum-dependent cell motility#GO:0001539;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cilium-dependent cell motility#GO:0060285;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;cell motility#GO:0048870 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000012123.3|UniProtKB=F7FU55 F7FU55 LOC100619459 PTHR26453:SF730 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021304.3|UniProtKB=A0A5F8G366 A0A5F8G366 MFN1 PTHR10465:SF2 TRANSMEMBRANE GTPASE FZO1 MITOFUSIN-1 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 organelle fusion#GO:0048284;mitochondrion organization#GO:0007005;mitochondrial fusion#GO:0008053;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitochondrion localization#GO:0051646;organelle localization#GO:0051640 mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000016929.2|UniProtKB=F6VN17 F6VN17 MSANTD7 PTHR47595:SF4 HEAT SHOCK 70 KDA PROTEIN 14 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 7 MONDO|Ensembl=ENSMODG00000008128.4|UniProtKB=F7ELU9 F7ELU9 AIMP2 PTHR13438:SF2 AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000041416.1|UniProtKB=A0A5F8GC81 A0A5F8GC81 MRPL47 PTHR21183:SF18 RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000048003.1|UniProtKB=A0A5F8GLG3 A0A5F8GLG3 LOC103096484 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000027603.2|UniProtKB=K7E5M2 K7E5M2 KRBA1 PTHR22740:SF3 PROTEIN KRBA1 KRAB DOMAIN-CONTAINING PROTEIN 3 MONDO|Ensembl=ENSMODG00000021226.4|UniProtKB=F6U0N6 F6U0N6 SLC16A14 PTHR11360:SF239 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 14 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000020863.3|UniProtKB=A0A5F8GN23 A0A5F8GN23 CEACAM16 PTHR44427:SF10 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CELL ADHESION MOLECULE CEACAM16 sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;nervous system process#GO:0050877;system process#GO:0003008;sensory perception of sound#GO:0007605;multicellular organismal process#GO:0032501 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000013990.3|UniProtKB=F6QKE5 F6QKE5 LDLRAP1 PTHR11232:SF35 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER LOW DENSITY LIPOPROTEIN RECEPTOR ADAPTER PROTEIN 1 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;regulation of biological process#GO:0050789;receptor internalization#GO:0031623;biological regulation#GO:0065007;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;plasma lipoprotein particle clearance#GO:0034381;import into cell#GO:0098657;localization#GO:0051179 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000001058.2|UniProtKB=F7E7S4 F7E7S4 FEM1A PTHR24173:SF12 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG A ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of response to stress#GO:0080134;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;catabolic process#GO:0009056;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;regulation of inflammatory response#GO:0050727;modification-dependent macromolecule catabolic process#GO:0043632;regulation of defense response#GO:0031347;protein catabolic process#GO:0030163 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000038104.1|UniProtKB=A0A5F8GPH8 A0A5F8GPH8 PTHR23267:SF482 IMMUNOGLOBULIN LIGHT CHAIN NON-FUNCTIONAL IMMUNOGLOBULIN KAPPA VARIABLE 6D-41-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000010315.4|UniProtKB=A0A5F8GAW6 A0A5F8GAW6 MYO1C PTHR13140:SF255 MYOSIN UNCONVENTIONAL MYOSIN-IC microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament-based movement#GO:0030048;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;cytoskeleton organization#GO:0007010;transport#GO:0006810;actin filament-based process#GO:0030029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microvillus#GO:0005902;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000023543.3|UniProtKB=F7DCU2 F7DCU2 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006273.3|UniProtKB=F7FDN5 F7FDN5 PTHR24242:SF253 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000011521.4|UniProtKB=F6RI15 F6RI15 BAP1 PTHR10589:SF28 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE BAP1 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000009191.4|UniProtKB=A0A5F8GVG9 A0A5F8GVG9 COG2 PTHR12961:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 2 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 2 organelle organization#GO:0006996;cellular component organization#GO:0016043;Golgi organization#GO:0007030;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;COG complex#GO:0017119;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000004440.4|UniProtKB=F6RTQ1 F6RTQ1 STAG3 PTHR11199:SF8 STROMAL ANTIGEN COHESIN SUBUNIT SA-3 binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;meiotic sister chromatid cohesion#GO:0051177 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000038689.1|UniProtKB=A0A5F8H424 A0A5F8H424 RASL12 PTHR24070:SF252 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-LIKE PROTEIN FAMILY MEMBER 12 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 Ras protein signal transduction#GO:0007265;establishment or maintenance of cell polarity#GO:0007163;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000049843.1|UniProtKB=A0A5F8H1X6 A0A5F8H1X6 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000011680.4|UniProtKB=A0A5F8H0U1 A0A5F8H0U1 STARD8 PTHR12659:SF3 RHO-TYPE GTPASE ACTIVATING PROTEIN STAR-RELATED LIPID TRANSFER PROTEIN 8 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;actin filament-based process#GO:0030029;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of Rho protein signal transduction#GO:0035023 GTPase-activating protein#PC00257;G-protein modulator#PC00022 PDGF signaling pathway#P00047>Rho#P01174 MONDO|Ensembl=ENSMODG00000040002.1|UniProtKB=A0A5F8HG07 A0A5F8HG07 PTHR24377:SF885 IP01015P-RELATED ZINC FINGER PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004822.4|UniProtKB=F6ULY9 F6ULY9 FNBP1L PTHR15735:SF14 FCH AND DOUBLE SH3 DOMAINS PROTEIN FORMIN-BINDING PROTEIN 1-LIKE cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;membrane invagination#GO:0010324;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;clathrin-dependent endocytosis#GO:0072583;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;localization#GO:0051179;plasma membrane organization#GO:0007009 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000051603.1|UniProtKB=A0A5F8GBE1 A0A5F8GBE1 APCDD1L PTHR31021:SF3 ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1 PROTEIN APCDD1-LIKE MONDO|Ensembl=ENSMODG00000010204.4|UniProtKB=F6SAU5 F6SAU5 LOC100028608 PTHR24300:SF400 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C9 tetrapyrrole binding#GO:0046906;binding#GO:0005488;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;response to xenobiotic stimulus#GO:0009410;olefinic compound metabolic process#GO:0120254;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000015672.4|UniProtKB=F7EI39 F7EI39 AACS PTHR42921:SF5 ACETOACETYL-COA SYNTHETASE ACETOACETYL-COA SYNTHETASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 positive regulation of protein secretion#GO:0050714;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of insulin secretion#GO:0050796;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of secretion by cell#GO:1903532;biological regulation#GO:0065007;positive regulation of secretion#GO:0051047;positive regulation of hormone secretion#GO:0046887;regulation of signaling#GO:0023051;regulation of hormone secretion#GO:0046883;regulation of secretion#GO:0051046;positive regulation of signaling#GO:0023056;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;regulation of protein secretion#GO:0050708;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of cell communication#GO:0010646 ligase#PC00142;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000007015.4|UniProtKB=F6XCE7 F6XCE7 NUCB2 PTHR19237:SF22 NUCLEOBINDIN NUCLEOBINDIN-2 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000038580.1|UniProtKB=A0A5F8GV05 A0A5F8GV05 PTHR24381:SF27 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 180 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000003364.3|UniProtKB=F6ZPQ4 F6ZPQ4 ACTR2 PTHR11937:SF37 ACTIN ACTIN-RELATED PROTEIN 2 structural molecule activity#GO:0005198;cytoskeletal protein binding#GO:0008092;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cell periphery#GO:0071944;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629 actin and actin related protein#PC00039 Cadherin signaling pathway#P00012>F-actin#P00470;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Huntington disease#P00029>Actin#P00807 MONDO|Ensembl=ENSMODG00000042726.1|UniProtKB=A0A5F8HLK7 A0A5F8HLK7 MMP19 PTHR10201:SF166 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-19 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 MONDO|Ensembl=ENSMODG00000028503.2|UniProtKB=K7E129 K7E129 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000049.4|UniProtKB=F6REK2 F6REK2 ARSD PTHR42693:SF5 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE D hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000008505.4|UniProtKB=F7FTF3 F7FTF3 RIPK1 PTHR44329:SF6 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED RECEPTOR-INTERACTING SERINE_THREONINE-PROTEIN KINASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;MAP kinase kinase kinase activity#GO:0004709;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;necroptotic process#GO:0070266;programmed cell death#GO:0012501;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cell death#GO:0008219;cellular response to stimulus#GO:0051716 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>RIP#P00315 MONDO|Ensembl=ENSMODG00000018771.4|UniProtKB=F7AE31 F7AE31 VPS45 PTHR11679:SF3 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 45 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000004739.4|UniProtKB=F6XJC5 F6XJC5 EPHB4 PTHR24416:SF296 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-B RECEPTOR 4 molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;response to stimulus#GO:0050896;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;ephrin receptor signaling pathway#GO:0048013;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;tube development#GO:0035295;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007935.5|UniProtKB=F7G951 F7G951 ABTB1 PTHR46231:SF1 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 MONDO|Ensembl=ENSMODG00000017424.4|UniProtKB=F7AIS9 F7AIS9 ZBTB8A PTHR46105:SF12 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 8A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020468.4|UniProtKB=A0A5F8G335 A0A5F8G335 PAWR PTHR15093:SF1 PROSTATE APOPTOSIS RESPONSE PROTEIN PAR-4 PRKC APOPTOSIS WT1 REGULATOR PROTEIN regulation of neuron apoptotic process#GO:0043523;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;positive regulation of neuron apoptotic process#GO:0043525;regulation of apoptotic process#GO:0042981;apoptotic signaling pathway#GO:0097190;positive regulation of apoptotic process#GO:0043065;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;cell death#GO:0008219;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;signaling#GO:0023052;cell communication#GO:0007154 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000039210.1|UniProtKB=A0A5F8GBY8 A0A5F8GBY8 PTHR14340:SF15 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 IG-LIKE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000011576.4|UniProtKB=F6XX24 F6XX24 INPP1 PTHR43028:SF3 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 INOSITOL POLYPHOSPHATE 1-PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;regulation of biological process#GO:0050789;cellular process#GO:0009987;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000001087.4|UniProtKB=A0A5F8GB44 A0A5F8GB44 ARFIP1 PTHR12141:SF4 ARFAPTIN-RELATED ARFAPTIN-1 molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin nucleation#GO:0051125;intracellular transport#GO:0046907;regulation of actin filament-based process#GO:0032970;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;trans-Golgi network membrane#GO:0032588;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791 vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000046165.1|UniProtKB=A0A5F8HD68 A0A5F8HD68 LOC100017853 PTHR48002:SF123 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4B1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000043700.1|UniProtKB=A0A5F8G6K0 A0A5F8G6K0 MYL12B PTHR23049:SF58 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 12B protein binding#GO:0005515;binding#GO:0005488;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092 intracellular organelle#GO:0043229;myofibril#GO:0030016;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;stress fiber#GO:0001725;membraneless organelle#GO:0043228;myosin complex#GO:0016459;contractile muscle fiber#GO:0043292;actomyosin#GO:0042641;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000015645.4|UniProtKB=A0A5F8GK11 A0A5F8GK11 SLC15A4 PTHR11654:SF80 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916;L-amino acid transmembrane transporter activity#GO:0015179;carboxylic acid transmembrane transporter activity#GO:0046943;basic amino acid transmembrane transporter activity#GO:0015174;aromatic amino acid transmembrane transporter activity#GO:0015173 import across plasma membrane#GO:0098739;cellular process#GO:0009987;oligopeptide transmembrane transport#GO:0035672;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;oligopeptide transport#GO:0006857;dipeptide transport#GO:0042938;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;amino acid transport#GO:0006865 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000022884.2|UniProtKB=F7GDY2 F7GDY2 LOC100024002 PTHR26450:SF106 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001163.4|UniProtKB=F7CK49 F7CK49 HMOX1 PTHR10720:SF1 HEME OXYGENASE HEME OXYGENASE 1 tetrapyrrole binding#GO:0046906;binding#GO:0005488;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 pigment metabolic process#GO:0042440;response to stress#GO:0006950;cellular process#GO:0009987;catabolic process#GO:0009056;response to stimulus#GO:0050896;heme metabolic process#GO:0042168;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;porphyrin-containing compound metabolic process#GO:0006778;response to oxidative stress#GO:0006979 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000009289.3|UniProtKB=A0A5F8GHK6 A0A5F8GHK6 PTHR22765:SF345 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING RING FINGER PROTEIN 215 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000010519.4|UniProtKB=A0A5F8HAQ0 A0A5F8HAQ0 FRZB PTHR11309:SF97 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;non-canonical Wnt signaling pathway#GO:0035567;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>FrzB#P01461;Angiogenesis#P00005>FRP#P00237 MONDO|Ensembl=ENSMODG00000011988.3|UniProtKB=F7B9A8 F7B9A8 KCNG2 PTHR11537:SF90 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL REGULATORY SUBUNIT KCNG2 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108 transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;action potential#GO:0001508;metal ion transport#GO:0030001 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000027786.2|UniProtKB=H9H9L0 H9H9L0 ZNF446 PTHR23226:SF210 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 446 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000040169.1|UniProtKB=F6VDP4 F6VDP4 PTHR12882:SF1 SUPPRESSOR OF TY 4 TRANSCRIPTION ELONGATION FACTOR SPT4 RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;binding#GO:0005488 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000000036.4|UniProtKB=F6S0C9 F6S0C9 ARSH PTHR42693:SF16 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE H hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000043090.1|UniProtKB=F6Q2J6 F6Q2J6 PTHR26450:SF40 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56A3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000051211.1|UniProtKB=A0A5F8G4G5 A0A5F8G4G5 PTHR15225:SF4 INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN N-MYC-INTERACTOR intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000039537.1|UniProtKB=A0A5F8H0W2 A0A5F8H0W2 SRL PTHR11216:SF1 EH DOMAIN SARCALUMENIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000003216.3|UniProtKB=H9H624 H9H624 TMEM150B PTHR21324:SF3 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED MODULATOR OF MACROAUTOPHAGY TMEM150B membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007996.4|UniProtKB=F7CLL4 F7CLL4 LRP2 PTHR22722:SF11 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2 binding#GO:0005488;hormone binding#GO:0042562 transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;signaling receptor complex#GO:0043235 Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173 MONDO|Ensembl=ENSMODG00000023947.3|UniProtKB=A0A5F8HDP5 A0A5F8HDP5 LOC103092471 PTHR11848:SF78 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 15 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000017564.4|UniProtKB=F7BSJ2 F7BSJ2 ENPP1 PTHR10151:SF77 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 1 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081 biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of bone mineralization#GO:0030500;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;establishment of localization#GO:0051234;regulation of cell differentiation#GO:0045595;transport#GO:0006810;negative regulation of cellular process#GO:0048523;regulation of developmental process#GO:0050793;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;localization#GO:0051179;regulation of multicellular organismal process#GO:0051239;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;small molecule metabolic process#GO:0044281;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;regulation of multicellular organismal development#GO:2000026;purine-containing compound metabolic process#GO:0072521;negative regulation of biological process#GO:0048519;phosphorus metabolic process#GO:0006793;inorganic anion transport#GO:0015698;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259 basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;cell surface#GO:0009986;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000044426.1|UniProtKB=A0A5F8GBJ2 A0A5F8GBJ2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001573.3|UniProtKB=F7ACM7 F7ACM7 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000039017.1|UniProtKB=A0A5F8GEU0 A0A5F8GEU0 PTHR33426:SF30 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000046771.1|UniProtKB=F7FE53 F7FE53 PTHR26452:SF310 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013274.3|UniProtKB=K7E2K7 K7E2K7 LSM5 PTHR20971:SF0 U6 SNRNA-ASSOCIATED PROTEIN U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U6 snRNP#GO:0005688;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Lsm2-8 complex#GO:0120115;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000006972.3|UniProtKB=F6QUQ6 F6QUQ6 ANG PTHR11437:SF60 RIBONUCLEASE ANGIOGENIN catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098 developmental process#GO:0032502;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune response#GO:0006955;multicellular organismal process#GO:0032501;response to other organism#GO:0051707;tube development#GO:0035295;response to bacterium#GO:0009617;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;anatomical structure development#GO:0048856;system development#GO:0048731;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;response to external biotic stimulus#GO:0043207;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;multicellular organism development#GO:0007275;antibacterial humoral response#GO:0019731;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;defense response to bacterium#GO:0042742;angiogenesis#GO:0001525;blood vessel morphogenesis#GO:0048514;defense response to Gram-positive bacterium#GO:0050830;anatomical structure morphogenesis#GO:0009653;response to stimulus#GO:0050896;circulatory system development#GO:0072359;biological process involved in interspecies interaction between organisms#GO:0044419 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 endoribonuclease#PC00094;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000015345.4|UniProtKB=F6WYF8 F6WYF8 CENPB PTHR19303:SF69 TRANSPOSON MAJOR CENTROMERE AUTOANTIGEN B binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000017109.4|UniProtKB=F6UJJ9 F6UJJ9 PHKA2 PTHR10749:SF5 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA, LIVER ISOFORM cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 MONDO|Ensembl=ENSMODG00000025321.2|UniProtKB=F6PS88 F6PS88 LOC100017278 PTHR19918:SF1 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED FIZZY-RELATED PROTEIN HOMOLOG enzyme regulator activity#GO:0030234;protein-containing complex binding#GO:0044877;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;binding#GO:0005488;enzyme activator activity#GO:0008047 macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;protein metabolic process#GO:0019538;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;proteasomal protein catabolic process#GO:0010498;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000011048.3|UniProtKB=F7EN14 F7EN14 RAB8B PTHR47980:SF6 LD44762P RAS-RELATED PROTEIN RAB-8B localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;secretion#GO:0046903;secretion by cell#GO:0032940;endocytic recycling#GO:0032456;export from cell#GO:0140352;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 trans-Golgi network transport vesicle#GO:0030140;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136;membrane#GO:0016020;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000001873.5|UniProtKB=F6YFT5 F6YFT5 MYO5A PTHR13140:SF273 MYOSIN UNCONVENTIONAL MYOSIN-VA cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657 cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 actin cytoskeleton#GO:0015629;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000017629.4|UniProtKB=F6ZSF4 F6ZSF4 ARHGAP18 PTHR14963:SF6 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 18 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of cellular component biogenesis#GO:0044087;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of small GTPase mediated signal transduction#GO:0051056;cellular component organization or biogenesis#GO:0071840;regulation of response to stimulus#GO:0048583;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of signal transduction#GO:0009966;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament polymerization#GO:0030833;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000010720.4|UniProtKB=F7G7L7 F7G7L7 HTR2B PTHR24247:SF31 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2B neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;cell-cell signaling#GO:0007267 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414 MONDO|Ensembl=ENSMODG00000045013.1|UniProtKB=A0A5F8GX53 A0A5F8GX53 SAMD5 PTHR12301:SF8 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 5 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 MONDO|Ensembl=ENSMODG00000010370.4|UniProtKB=F6TAJ1 F6TAJ1 PLEC PTHR23169:SF20 ENVOPLAKIN PLECTIN structural molecule activity#GO:0005198;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200 intermediate filament-based process#GO:0045103;wound healing#GO:0042060;cellular component organization#GO:0016043;cell-substrate junction assembly#GO:0007044;cell junction assembly#GO:0034329;cell junction organization#GO:0034330;intermediate filament cytoskeleton organization#GO:0045104;response to stimulus#GO:0050896;cell-substrate junction organization#GO:0150115;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;response to wounding#GO:0009611;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;membrane#GO:0016020;intermediate filament#GO:0005882;sarcolemma#GO:0042383;cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular fiber#GO:0099512;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 intermediate filament#PC00129;intermediate filament binding protein#PC00130 MONDO|Ensembl=ENSMODG00000012630.4|UniProtKB=F6R7P7 F6R7P7 CLMN PTHR47535:SF7 MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G CALMIN actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;negative regulation of cell population proliferation#GO:0008285;cellular localization#GO:0051641;regulation of cell population proliferation#GO:0042127;localization#GO:0051179;organelle localization#GO:0051640;regulation of cellular process#GO:0050794;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;nuclear migration#GO:0007097;negative regulation of biological process#GO:0048519 membrane#GO:0016020;nucleus#GO:0005634;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;nuclear protein-containing complex#GO:0140513;nuclear membrane#GO:0031965;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000029595.2|UniProtKB=K7DZI0 K7DZI0 LOC103092432 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000000228.3|UniProtKB=F6SYQ9 F6SYQ9 GCHFR PTHR16852:SF2 GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000043503.1|UniProtKB=A0A5F8GTR9 A0A5F8GTR9 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000014935.3|UniProtKB=F7FIQ6 F7FIQ6 PTHR10445:SF0 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;protein-containing complex#GO:0032991;transferase complex#GO:1990234;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription regulation#P00023>TFIIFbeta#P00667;Transcription regulation by bZIP transcription factor#P00055>TFIIFbeta#P01396 MONDO|Ensembl=ENSMODG00000020865.3|UniProtKB=A0A5F8H4F6 A0A5F8H4F6 PTHR23277:SF109 NECTIN-RELATED POLIOVIRUS RECEPTOR cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;virus receptor activity#GO:0001618;protein binding#GO:0005515 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;natural killer cell mediated cytotoxicity#GO:0042267;immune effector process#GO:0002252;cell killing#GO:0001906;response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;homophilic cell-cell adhesion#GO:0007156;response to stress#GO:0006950;cell-cell adhesion#GO:0098609;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;cell adhesion#GO:0007155;immune system process#GO:0002376;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;natural killer cell mediated immunity#GO:0002228;leukocyte mediated cytotoxicity#GO:0001909 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell junction#GO:0030054 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000050796.1|UniProtKB=K7E1Z4 K7E1Z4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008620.3|UniProtKB=F6PH18 F6PH18 FAXDC2 PTHR11863:SF241 STEROL DESATURASE FATTY ACID HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2 monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;primary metabolic process#GO:0044238;cellular process#GO:0009987 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 oxidase#PC00175 MONDO|Ensembl=ENSMODG00000018378.4|UniProtKB=F6QVR2 F6QVR2 SLC6A12 PTHR11616:SF118 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT BETAINE TRANSPORTER solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810;amino acid transport#GO:0006865 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000051475.1|UniProtKB=A0A5F8H040 A0A5F8H040 ZNRF1 PTHR46661:SF2 E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE ZNRF1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein K48-linked ubiquitination#GO:0070936;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000005725.4|UniProtKB=A0A5F8GBG4 A0A5F8GBG4 SLC25A25 PTHR24089:SF762 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL ADENYL NUCLEOTIDE ANTIPORTER SLC25A25 nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;phosphate transmembrane transporter activity#GO:0005315;active transmembrane transporter activity#GO:0022804;purine nucleotide transmembrane transporter activity#GO:0015216;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;carbohydrate derivative transport#GO:1901264;nitrogen compound transport#GO:0071705 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000039894.1|UniProtKB=K7E4H1 K7E4H1 PTHR46890:SF56 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED OS06G0484800 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000005543.3|UniProtKB=F7FHH1 F7FHH1 KAT14 PTHR20916:SF26 CYSTEINE AND GLYCINE-RICH PROTEIN 2 BINDING PROTEIN CYSTEINE-RICH PROTEIN 2-BINDING PROTEIN protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 MONDO|Ensembl=ENSMODG00000007993.4|UniProtKB=F7D5B1 F7D5B1 CYP2F1 PTHR24300:SF275 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2F1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;tetrapyrrole binding#GO:0046906;binding#GO:0005488 xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;olefinic compound metabolic process#GO:0120254;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;response to xenobiotic stimulus#GO:0009410;cellular response to xenobiotic stimulus#GO:0071466;icosanoid metabolic process#GO:0006690;response to chemical#GO:0042221;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000009149.2|UniProtKB=F7B0T2 F7B0T2 PTHR26452:SF22 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000006397.4|UniProtKB=A0A5F8GZY6 A0A5F8GZY6 LIN52 PTHR31489:SF2 LIN52 FAMILY MEMBER PROTEIN LIN-52 HOMOLOG MONDO|Ensembl=ENSMODG00000006955.4|UniProtKB=F6QW04 F6QW04 DHX9 PTHR18934:SF119 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE A RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000011921.4|UniProtKB=F7DZE9 F7DZE9 PTHR26450:SF104 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011886.4|UniProtKB=F7FSI2 F7FSI2 SLC23A1 PTHR11119:SF21 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SOLUTE CARRIER FAMILY 23 MEMBER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;sugar transmembrane transporter activity#GO:0051119;solute:monoatomic cation symporter activity#GO:0015294;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;carbohydrate transmembrane transporter activity#GO:0015144;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;carbohydrate transport#GO:0008643;carboxylic acid transmembrane transport#GO:1905039;carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180;cellular process#GO:0009987 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000015029.4|UniProtKB=F7FUL6 F7FUL6 CDH13 PTHR24027:SF80 CADHERIN-23 CADHERIN-13 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cell motility#GO:0048870;cell migration#GO:0016477;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000001436.3|UniProtKB=F7BCE9 F7BCE9 SMN1 PTHR13681:SF27 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED SURVIVAL MOTOR NEURON PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;ribonucleoprotein complex biogenesis#GO:0022613;cell development#GO:0048468;mRNA metabolic process#GO:0016071;animal gross anatomical part developmental process#GO:0160108;nucleic acid biosynthetic process#GO:0141187;generation of neurons#GO:0048699;RNA metabolic process#GO:0016070;neuron development#GO:0048666;axonogenesis#GO:0007409;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;protein-RNA complex organization#GO:0071826;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cell projection morphogenesis#GO:0048858;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;anatomical structure development#GO:0048856;system development#GO:0048731;axon development#GO:0061564;macromolecule biosynthetic process#GO:0009059;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;neurogenesis#GO:0022008 SMN complex#GO:0032797;membrane-bounded organelle#GO:0043227;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000008817.4|UniProtKB=F6QA54 F6QA54 NAPA PTHR13768:SF23 SOLUBLE NSF ATTACHMENT PROTEIN SNAP ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;protein transport#GO:0015031;cellular localization#GO:0051641;cellular component disassembly#GO:0022411;synaptic transmission, glutamatergic#GO:0035249;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic signaling#GO:0099536;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;protein-containing complex disassembly#GO:0032984;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;chemical synaptic transmission#GO:0007268;localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907 membrane protein complex#GO:0098796;SNARE complex#GO:0031201;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron projection terminus#GO:0044306;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;terminal bouton#GO:0043195;distal axon#GO:0150034;axon#GO:0030424;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;presynapse#GO:0098793;neuron projection#GO:0043005;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cell junction#GO:0030054;axon terminus#GO:0043679 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000000098.3|UniProtKB=F6YCC9 F6YCC9 NDUFC1 PTHR17097:SF0 NADH-UBIQUINONE OXIDOREDUCTASE KFYI SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 SUBUNIT C1, MITOCHONDRIAL protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000045107.1|UniProtKB=A0A5F8HHX1 A0A5F8HHX1 PTHR26450:SF141 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000051252.1|UniProtKB=A0A5F8H454 A0A5F8H454 LOC100026636 PTHR10177:SF444 CYCLINS CYCLIN-A2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082 serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;transferase complex#GO:1990234;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin A#P04666 MONDO|Ensembl=ENSMODG00000038601.1|UniProtKB=A0A5F8HAS6 A0A5F8HAS6 LOC103106173 PTHR13999:SF4 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 3 cytokine-mediated signaling pathway#GO:0019221;response to virus#GO:0009615;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune response#GO:0006955;response to other organism#GO:0051707;biological regulation#GO:0065007;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;response to peptide#GO:1901652;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;defense response to virus#GO:0051607;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;response to type II interferon#GO:0034341;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000020748.3|UniProtKB=F6ZZW4 F6ZZW4 SLC10A6 PTHR10361:SF55 SODIUM-BILE ACID COTRANSPORTER SODIUM-DEPENDENT ORGANIC ANION TRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;bile acid transmembrane transporter activity#GO:0015125;solute:sodium symporter activity#GO:0015370 lipid transport#GO:0006869;macromolecule localization#GO:0033036;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;establishment of localization#GO:0051234;bile acid and bile salt transport#GO:0015721;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000025588.3|UniProtKB=F6U2A3 F6U2A3 PTHR15727:SF4 RING FINGER PROTEIN 214 E3 UBIQUITIN-PROTEIN LIGASE DZIP3 transferase activity#GO:0016740;polyubiquitin modification-dependent protein binding#GO:0031593;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;nucleic acid binding#GO:0003676;modification-dependent protein binding#GO:0140030;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;RNA binding#GO:0003723;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000013332.4|UniProtKB=A0A5F8GYV4 A0A5F8GYV4 TECPR2 PTHR23287:SF16 RUBY-EYE2-LIKE PROTEIN TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000021263.4|UniProtKB=A0A5F8GQQ0 A0A5F8GQQ0 TM4SF18 PTHR14198:SF14 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 18 membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000014750.4|UniProtKB=F6ZE90 F6ZE90 TBC1D5 PTHR22957:SF337 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 5 GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;retromer complex#GO:0030904;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000005815.4|UniProtKB=F6WY21 F6WY21 ABCC6 PTHR24223:SF339 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 6 ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;xenobiotic transmembrane transporter activity#GO:0042910;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000002581.4|UniProtKB=F7G570 F7G570 PTHR10560:SF0 THROMBOPOIETIN THROMBOPOIETIN signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;chemokine-mediated signaling pathway#GO:0070098;cytokine-mediated signaling pathway#GO:0019221;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;cellular response to chemokine#GO:1990869;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of cell population proliferation#GO:0008284;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;regulation of ERK1 and ERK2 cascade#GO:0070372;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to chemokine#GO:1990868 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000002425.4|UniProtKB=A0A5F8GUQ7 A0A5F8GUQ7 ZNF821 PTHR24404:SF1 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 821 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000022912.1|UniProtKB=F6PZT2 F6PZT2 LOC100022107 PTHR26450:SF164 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51B2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008537.4|UniProtKB=F7DHA5 F7DHA5 TIMD4 PTHR46608:SF3 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;ion binding#GO:0043167;small molecule binding#GO:0036094;phospholipid binding#GO:0005543;anion binding#GO:0043168;binding#GO:0005488 endocytosis#GO:0006897;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;apoptotic cell clearance#GO:0043277;phagocytosis#GO:0006909;transport#GO:0006810 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000001738.4|UniProtKB=F6WZW9 F6WZW9 HSD3B7 PTHR10366:SF847 NAD DEPENDENT EPIMERASE/DEHYDRATASE 3 BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 7 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 metabolite interconversion enzyme#PC00262;lyase#PC00144;dehydratase#PC00091 Androgen/estrogene/progesterone biosynthesis#P02727>3beta-hydroxy-Delta5-steroid dehydrogenase#P02837 MONDO|Ensembl=ENSMODG00000025343.2|UniProtKB=F6ZAU2 F6ZAU2 PTHR11904:SF12 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;purine-containing compound catabolic process#GO:0072523;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule catabolic process#GO:0034656;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleoside catabolic process#GO:0009164;nucleotide metabolic process#GO:0009117;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;glycosyl compound catabolic process#GO:1901658;nucleoside phosphate biosynthetic process#GO:1901293;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;pyridine-containing compound metabolic process#GO:0072524;purine nucleoside metabolic process#GO:0042278 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137;nucleotide kinase#PC00172 Xanthine and guanine salvage pathway#P02788>Guanosine phosphorylase#P03250;Adenine and hypoxanthine salvage pathway#P02723>Deoxyinosine phosphorylase#P02812;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphorylase#P02805;Purine metabolism#P02769>Nucleoside Phosphorylase#P03115;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine phosphorylase#P02808;Adenine and hypoxanthine salvage pathway#P02723>Inosine phosphorylase#P02813;Xanthine and guanine salvage pathway#P02788>Deoxyguanosine phosphorylase#P03248 MONDO|Ensembl=ENSMODG00000014444.3|UniProtKB=F7ATW7 F7ATW7 EIPR1 PTHR14205:SF15 WD-REPEAT PROTEIN EARP AND GARP COMPLEX-INTERACTING PROTEIN 1 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 MONDO|Ensembl=ENSMODG00000050881.1|UniProtKB=A0A5F8GQ15 A0A5F8GQ15 DTWD2 PTHR21392:SF0 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2 MONDO|Ensembl=ENSMODG00000003178.4|UniProtKB=F6VY61 F6VY61 PTHR24356:SF140 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE_THREONINE-PROTEIN KINASE 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;signal transduction#GO:0007165;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000002531.4|UniProtKB=F7AME6 F7AME6 SYNRG PTHR15463:SF2 AP1 GAMMA SUBUNIT BINDING PROTEIN 1 SYNERGIN GAMMA trans-Golgi network transport vesicle#GO:0030140;membrane coat#GO:0030117;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;clathrin-coated vesicle#GO:0030136;Golgi-associated vesicle#GO:0005798;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;intracellular organelle#GO:0043229;coated membrane#GO:0048475;coated vesicle#GO:0030135;intracellular vesicle#GO:0097708;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle membrane#GO:0030665;bounding membrane of organelle#GO:0098588;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle coat#GO:0030120 MONDO|Ensembl=ENSMODG00000006488.3|UniProtKB=F7F2J1 F7F2J1 RHO PTHR24240:SF15 OPSIN RHODOPSIN signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;response to radiation#GO:0009314;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;signal transduction#GO:0007165;detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;signaling#GO:0023052;cellular response to radiation#GO:0071478;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cilium#GO:0005929;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;photoreceptor outer segment#GO:0001750;organelle#GO:0043226 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin#P00747 MONDO|Ensembl=ENSMODG00000001725.4|UniProtKB=A0A5F8GEB6 A0A5F8GEB6 SLC12A6 PTHR11827:SF66 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 6 potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic anion transport#GO:0006820;cellular process#GO:0009987 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000048031.1|UniProtKB=A0A5F8GCD4 A0A5F8GCD4 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017194.3|UniProtKB=F6XXJ8 F6XXJ8 TMEM203 PTHR13568:SF9 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 203 calcium ion homeostasis#GO:0055074;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000024726.1|UniProtKB=F7EXT1 F7EXT1 LOC100019980 PTHR13362:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S33 SMALL RIBOSOMAL SUBUNIT PROTEIN MS33 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000007513.4|UniProtKB=F7GJX5 F7GJX5 FADS3 PTHR19353:SF11 FATTY ACID DESATURASE 2 FATTY ACID DESATURASE 3 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000015344.4|UniProtKB=F6WYE1 F6WYE1 RIC1 PTHR22746:SF11 RAB6A-GEF COMPLEX PARTNER PROTEIN 1 GUANINE NUCLEOTIDE EXCHANGE FACTOR SUBUNIT RIC1 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 protein localization to cell junction#GO:1902414;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;developmental process#GO:0032502;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;intracellular protein localization#GO:0008104;neurogenesis#GO:0022008;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cytosolic transport#GO:0016482;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cellular localization#GO:0051641;axonogenesis#GO:0007409;neuron development#GO:0048666;protein transport#GO:0015031;neuron projection development#GO:0031175;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;protein localization to synapse#GO:0035418;endosomal transport#GO:0016197;cell projection morphogenesis#GO:0048858 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000023384.2|UniProtKB=A0A5F8HBF0 A0A5F8HBF0 FUT9 PTHR11929:SF10 ALPHA- 1,3 -FUCOSYLTRANSFERASE 4-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 3-ALPHA-L-FUCOSYLTRANSFERASE 9 glycosyltransferase activity#GO:0016757;alpha-(1->3)-fucosyltransferase activity#GO:0046920;transferase activity#GO:0016740;catalytic activity#GO:0003824;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000013370.4|UniProtKB=A0A5F8H0X0 A0A5F8H0X0 ACTN4 PTHR11915:SF425 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-4 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;cellular component organization#GO:0016043;muscle cell development#GO:0055001;cell development#GO:0048468;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154 intracellular organelle#GO:0043229;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cytoskeleton#GO:0005856;I band#GO:0031674;cell junction#GO:0030054;sarcomere#GO:0030017;membraneless organelle#GO:0043228;membrane#GO:0016020;contractile muscle fiber#GO:0043292;cell periphery#GO:0071944;Z disc#GO:0030018;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 MONDO|Ensembl=ENSMODG00000006248.3|UniProtKB=F7FEC7 F7FEC7 ISCA2 PTHR43011:SF1 IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;iron-sulfur cluster binding#GO:0051536;metal ion binding#GO:0046872 protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;iron-sulfur cluster assembly#GO:0016226;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000043284.1|UniProtKB=A0A5F8G562 A0A5F8G562 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000003005.4|UniProtKB=F6Q3H7 F6Q3H7 PIK3CD PTHR10048:SF35 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 lipid biosynthetic process#GO:0008610;cell migration#GO:0016477;glycerophospholipid metabolic process#GO:0006650;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;cell motility#GO:0048870;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;phosphatidylinositol phosphate biosynthetic process#GO:0046854 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622 kinase#PC00137 Integrin signalling pathway#P00034>PI3K#P00936;Axon guidance mediated by netrin#P00009>PI3K#P00363;p53 pathway feedback loops 2#P04398>PI3K#P04661;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Hypoxia response via HIF activation#P00030>PI3K#P00823;PDGF signaling pathway#P00047>PI3K#P01168;Ras Pathway#P04393>PI3K#P04567;Apoptosis signaling pathway#P00006>PI3K#P00310;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;VEGF signaling pathway#P00056>PI3K#P01413;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;T cell activation#P00053>PI3K#P01322;FGF signaling pathway#P00021>PI3K#P00640;B cell activation#P00010>PI3K#P00391;EGF receptor signaling pathway#P00018>PI3K#P00557;Angiogenesis#P00005>PI3K#P00236 MONDO|Ensembl=ENSMODG00000007891.4|UniProtKB=F6ZG72 F6ZG72 MCM2 PTHR11630:SF44 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM2 macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094 response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;nuclear DNA replication#GO:0033260;mitotic DNA replication#GO:1902969;DNA repair#GO:0006281;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;DNA replication initiation#GO:0006270;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;mitotic cell cycle process#GO:1903047;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;DNA replication#GO:0006260;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261 MCM complex#GO:0042555;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000015151.4|UniProtKB=F7CFR9 F7CFR9 RBM28 PTHR48039:SF7 RNA-BINDING MOTIF PROTEIN 14B RNA-BINDING PROTEIN 28 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000021539.2|UniProtKB=F7DZR8 F7DZR8 SNRPD2 PTHR12777:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2 SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;spliceosomal snRNP assembly#GO:0000387 catalytic step 2 spliceosome#GO:0071013;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686;cytoplasm#GO:0005737;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000046451.1|UniProtKB=A0A5F8G3B0 A0A5F8G3B0 PTHR23304:SF189 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000023192.2|UniProtKB=A0A5F8HGF8 A0A5F8HGF8 PTHR14625:SF3 MICROCEPHALIN MICROCEPHALIN mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cellular process#GO:0009987 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 MONDO|Ensembl=ENSMODG00000039312.1|UniProtKB=K7E5H3 K7E5H3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010593.3|UniProtKB=F7G8H7 F7G8H7 PLEKHA2 PTHR14336:SF5 TANDEM PH DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 2 ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;phospholipid binding#GO:0005543;small molecule binding#GO:0036094;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000015542.4|UniProtKB=F6SKQ6 F6SKQ6 LNPEP PTHR11533:SF42 PROTEASE M1 ZINC METALLOPROTEASE LEUCYL-CYSTINYL AMINOPEPTIDASE metalloexopeptidase activity#GO:0008235;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238 multicellular organismal process#GO:0032501;blood circulation#GO:0008015;biological regulation#GO:0065007;regulation of blood pressure#GO:0008217;cellular process#GO:0009987;peptide catabolic process#GO:0043171;macromolecule metabolic process#GO:0043170;system process#GO:0003008;metabolic process#GO:0008152;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;peptide metabolic process#GO:0006518;circulatory system process#GO:0003013;proteolysis#GO:0006508 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000005679.4|UniProtKB=A0A5F8GIY0 A0A5F8GIY0 SH3TC2 PTHR22647:SF2 SH3 DOMAIN AND TETRATRICOPEPTIDE REPEATS CONTAINING PROTEIN SH3 DOMAIN AND TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;regulation of establishment of protein localization#GO:0070201;regulation of transport#GO:0051049;regulation of protein localization#GO:0032880;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018683.4|UniProtKB=F7AEE9 F7AEE9 PROC PTHR24278:SF0 COAGULATION FACTOR VITAMIN K-DEPENDENT PROTEIN C catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 Blood coagulation#P00011>PC#P00426;Blood coagulation#P00011>APC#P00423 MONDO|Ensembl=ENSMODG00000037227.1|UniProtKB=A0A5F8G202 A0A5F8G202 LOC103095529 PTHR24100:SF156 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 2 MEMBER A2 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000003365.4|UniProtKB=F6ZPP5 F6ZPP5 APTX PTHR12486:SF4 APRATAXIN-RELATED APRATAXIN nucleic acid binding#GO:0003676;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;double-stranded RNA binding#GO:0003725;single-stranded DNA binding#GO:0003697;hydrolase activity#GO:0016787;RNA binding#GO:0003723;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;damaged DNA binding#GO:0003684 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 MONDO|Ensembl=ENSMODG00000046448.1|UniProtKB=A0A5F8GUZ0 A0A5F8GUZ0 PTHR23299:SF63 METALLOTHIONEIN METALLOTHIONEIN metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;response to metal ion#GO:0010038;response to cadmium ion#GO:0046686;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;response to stress#GO:0006950;detoxification of inorganic compound#GO:0061687;detoxification#GO:0098754;response to chemical#GO:0042221;inorganic ion homeostasis#GO:0098771;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;response to toxic substance#GO:0009636;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000016099.5|UniProtKB=F7EB43 F7EB43 ZMIZ2 PTHR10782:SF38 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN 2 acyltransferase activity#GO:0016746;transcription regulator activity#GO:0140110;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;molecular function inhibitor activity#GO:0140678;transferase activity#GO:0016740;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;catalytic activity, acting on a protein#GO:0140096;transcription coactivator activity#GO:0003713;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;metabolic process#GO:0008152;protein sumoylation#GO:0016925;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;negative regulation of biological process#GO:0048519;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648 organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000023206.1|UniProtKB=F7CMS2 F7CMS2 TNFAIP8L2 PTHR12757:SF4 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8-LIKE PROTEIN 2 regulation of response to external stimulus#GO:0032101;regulation of T cell activation#GO:0050863;negative regulation of cell-cell adhesion#GO:0022408;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;negative regulation of response to external stimulus#GO:0032102;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cell adhesion#GO:0030155;negative regulation of response to stimulus#GO:0048585;negative regulation of cell adhesion#GO:0007162;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of cell activation#GO:0050866;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of response to stimulus#GO:0048583;regulation of cell-cell adhesion#GO:0022407;negative regulation of inflammatory response#GO:0050728;regulation of immune system process#GO:0002682;negative regulation of defense response#GO:0031348;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of leukocyte cell-cell adhesion#GO:1903038;negative regulation of multicellular organismal process#GO:0051241;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;negative regulation of T cell activation#GO:0050868 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000015339.4|UniProtKB=F6XEQ0 F6XEQ0 IHH PTHR11889:SF39 HEDGEHOG INDIAN HEDGEHOG PROTEIN protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;signaling receptor binding#GO:0005102;calcium ion binding#GO:0005509 developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell fate specification#GO:0001708;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224;cell fate commitment#GO:0045165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000039203.1|UniProtKB=K7DZR4 K7DZR4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000024971.2|UniProtKB=F6QLU4 F6QLU4 PTHR12226:SF3 MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED SOLUTE CARRIER FAMILY 66 MEMBER 3 MONDO|Ensembl=ENSMODG00000003715.3|UniProtKB=F7EWL3 F7EWL3 SPG7 PTHR43655:SF8 ATP-DEPENDENT PROTEASE MITOCHONDRIAL INNER MEMBRANE M-AAA PROTEASE COMPONENT PARAPLEGIN catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;peptidase complex#GO:1905368;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000008105.3|UniProtKB=F7G5U6 F7G5U6 ANKRD61 PTHR24197:SF52 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 61 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 61 protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000012821.3|UniProtKB=F7DY13 F7DY13 ELOVL6 PTHR11157:SF125 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 6 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000010889.2|UniProtKB=F7FJD8 F7FJD8 ERLIN2 PTHR15351:SF4 ERLIN (ER LIPID RAFT ASSOCIATED PROTEIN) HOMOLOG ERLIN-2 response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;cell communication#GO:0007154;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;SREBP signaling pathway#GO:0032933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 MONDO|Ensembl=ENSMODG00000025494.3|UniProtKB=F6QYK0 F6QYK0 PTHR14677:SF11 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED AN1-TYPE ZINC FINGER PROTEIN 2A metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;ubiquitin-dependent protein catabolic process#GO:0006511;protein targeting to ER#GO:0045047;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to endoplasmic reticulum#GO:0072599;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;localization#GO:0051179;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;protein targeting#GO:0006605 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000020770.4|UniProtKB=F6ZA47 F6ZA47 MAPK10 PTHR24055:SF162 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 10 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;JNK cascade#GO:0007254;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Angiogenesis#P00005>JNK1#P00221;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Ras Pathway#P04393>JNK#P04572;B cell activation#P00010>Jnk#P00402;PDGF signaling pathway#P00047>ERK#P01143;CCKR signaling map#P06959>MAPK8-10#P07090;Apoptosis signaling pathway#P00006>JNK#P00274;Integrin signalling pathway#P00034>ERK#P00907;Parkinson disease#P00049>SAPK#P01219;Toll receptor signaling pathway#P00054>JNK#P01375;Oxidative stress response#P00046>JNK1/2#P01129;FGF signaling pathway#P00021>JNK1-3#P00628;TGF-beta signaling pathway#P00052>JNK#P01284;T cell activation#P00053>Jnk#P01336;FAS signaling pathway#P00020>JNK#P00615;EGF receptor signaling pathway#P00018>JNK1-3#P00545;Integrin signalling pathway#P00034>Jnk#P00951 MONDO|Ensembl=ENSMODG00000036449.1|UniProtKB=A0A5F8G1N7 A0A5F8G1N7 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011207.4|UniProtKB=F7CHM1 F7CHM1 TIGD5 PTHR19303:SF56 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 5 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000015979.2|UniProtKB=A0A5F8GHN4 A0A5F8GHN4 PTHR28359:SF1 ASHWIN TRNA-SPLICING LIGASE COMPLEX SUBUNIT ASW RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000047370.1|UniProtKB=A0A5F8GLM1 A0A5F8GLM1 PTHR11334:SF60 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G-PROTEIN COUPLED RECEPTOR MEMBER H G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004049.3|UniProtKB=F7C3W6 F7C3W6 PTHR11334:SF57 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G PROTEIN-COUPLED RECEPTOR MEMBER D plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000510.4|UniProtKB=F6Y610 F6Y610 LOC100014635 PTHR24247:SF14 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 5B molecular transducer activity#GO:0060089;cation binding#GO:0043169;serotonin binding#GO:0051378;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;heterocyclic compound binding#GO:1901363;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227 response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 MONDO|Ensembl=ENSMODG00000043586.1|UniProtKB=A0A5F8HGN7 A0A5F8HGN7 HOXC6 PTHR45659:SF1 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-C6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000017157.4|UniProtKB=F6QE05 F6QE05 RBBP7 PTHR22850:SF82 WD40 REPEAT FAMILY HISTONE-BINDING PROTEIN RBBP7 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;PcG protein complex#GO:0031519;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000021329.4|UniProtKB=H9H7X3 H9H7X3 CHKA PTHR22603:SF36 CHOLINE/ETHANOALAMINE KINASE CHOLINE KINASE ALPHA phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;phosphatidylcholine metabolic process#GO:0046470;phosphatidylcholine biosynthetic process#GO:0006656;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 MONDO|Ensembl=ENSMODG00000011732.4|UniProtKB=F7FSS2 F7FSS2 FBXW4 PTHR14381:SF1 DACTYLIN F-BOX_WD REPEAT-CONTAINING PROTEIN 4 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;DNA damage response#GO:0006974;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;protein metabolic process#GO:0019538;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716 catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461 MONDO|Ensembl=ENSMODG00000049307.1|UniProtKB=A0A5F8HCA9 A0A5F8HCA9 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000046032.1|UniProtKB=A0A5F8H6R6 A0A5F8H6R6 PTHR46771:SF3 DETERIN BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5 negative regulation of apoptotic process#GO:0043066;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;organelle organization#GO:0006996;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;negative regulation of cellular process#GO:0048523;chromosome segregation#GO:0007059;regulation of apoptotic process#GO:0042981;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;regulation of cellular process#GO:0050794;mitotic cytokinesis#GO:0000281;regulation of programmed cell death#GO:0043067;cell cycle#GO:0007049;negative regulation of biological process#GO:0048519;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cell division#GO:0051301;cytoskeleton-dependent cytokinesis#GO:0061640;microtubule cytoskeleton organization#GO:0000226;cytokinesis#GO:0000910 spindle#GO:0005819;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular organelle#GO:0043229;spindle midzone#GO:0051233;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;kinetochore#GO:0000776;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Angiogenesis#P00005>Survivin#P00198 MONDO|Ensembl=ENSMODG00000002142.3|UniProtKB=F6YF57 F6YF57 CBX4 PTHR46727:SF1 E3 SUMO-PROTEIN LIGASE CBX4 E3 SUMO-PROTEIN LIGASE CBX4 binding#GO:0005488;acyltransferase activity#GO:0016746;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;macromolecule modification#GO:0043412;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;metabolic process#GO:0008152;protein sumoylation#GO:0016925 protein-containing complex#GO:0032991;PcG protein complex#GO:0031519;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000040491.1|UniProtKB=A0A5F8H0J7 A0A5F8H0J7 LOC100013013 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006435.4|UniProtKB=F7EZ55 F7EZ55 FSTL3 PTHR10913:SF16 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 3 activin binding#GO:0048185;binding#GO:0005488;protein-containing complex binding#GO:0044877 regulation of cell communication#GO:0010646;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000036709.1|UniProtKB=A0A5F8GFF8 A0A5F8GFF8 LOC100619355 PTHR10666:SF438 UBIQUITIN UBIQUITIN-RIBOSOMAL PROTEIN ES31 FUSION PROTEIN structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;nucleus#GO:0005634;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000024778.2|UniProtKB=F7C721 F7C721 PTHR35156:SF1 TESTIS-EXPRESSED PROTEIN 52 TESTIS-EXPRESSED PROTEIN 52 MONDO|Ensembl=ENSMODG00000020919.3|UniProtKB=F6W395 F6W395 PTHR26453:SF45 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025042.1|UniProtKB=F6W7S6 F6W7S6 NPY4R2 PTHR24235:SF25 NEUROPEPTIDE Y RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 4-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014543.3|UniProtKB=F7E9B9 F7E9B9 EAF1 PTHR15970:SF8 ELL-ASSOCIATED FACTOR EAF ELL-ASSOCIATED FACTOR 1 transcription regulator activity#GO:0140110;transcription elongation factor activity#GO:0003711 transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000000396.5|UniProtKB=F6RP28 F6RP28 ZSWIM8 PTHR22619:SF1 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 8 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul2-RING ubiquitin ligase complex#GO:0031462;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535 MONDO|Ensembl=ENSMODG00000002677.3|UniProtKB=F7CYX5 F7CYX5 NOB1 PTHR12814:SF2 RNA-BINDING PROTEIN NOB1 RNA-BINDING PROTEIN NOB1 catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000016861.5|UniProtKB=A0A5F8GX77 A0A5F8GX77 MEF2D PTHR11945:SF23 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2D cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MADS box transcription factor#PC00250 p38 MAPK pathway#P05918>MEF#P06023;CCKR signaling map#P06959>MEF2#P07032;CCKR signaling map#P06959>MEF2D#P07048 MONDO|Ensembl=ENSMODG00000002460.3|UniProtKB=F7F1R9 F7F1R9 POU3F3 PTHR11636:SF125 POU DOMAIN POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 3 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000024731.1|UniProtKB=F7EEV8 F7EEV8 TLNRD1 PTHR47133:SF1 TALIN ROD DOMAIN-CONTAINING PROTEIN 1 TALIN ROD DOMAIN-CONTAINING PROTEIN 1 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 MONDO|Ensembl=ENSMODG00000039945.1|UniProtKB=F7DBL9 F7DBL9 PTHR23226:SF425 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 24 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025364.2|UniProtKB=F7D195 F7D195 PTHR15825:SF4 UBIQUITIN-FOLD MODIFIER 1 UBIQUITIN-FOLD MODIFIER 1 cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;process utilizing autophagic mechanism#GO:0061919;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;autophagy#GO:0006914;response to stress#GO:0006950;reticulophagy#GO:0061709;macroautophagy#GO:0016236;response to stimulus#GO:0050896;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000043161.1|UniProtKB=A0A5F8HG14 A0A5F8HG14 PTHR26450:SF128 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025699.3|UniProtKB=F6TJ06 F6TJ06 PTHR24291:SF39 CYTOCHROME P450 FAMILY 4 TAUROCHENODEOXYCHOLIC 6 ALPHA-HYDROXYLASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000046374.1|UniProtKB=A0A5F8H4S4 A0A5F8H4S4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008163.4|UniProtKB=F7EL24 F7EL24 LMO4 PTHR45787:SF5 LD11652P LIM DOMAIN TRANSCRIPTION FACTOR LMO4 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;cell fate specification#GO:0001708;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cell fate commitment#GO:0045165;regulation of biological process#GO:0050789;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of primary metabolic process#GO:0080090;neuron fate commitment#GO:0048663;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000048979.1|UniProtKB=A0A5F8HFW6 A0A5F8HFW6 PTHR36291:SF1 UBAP1-MVB12-ASSOCIATED (UMA)-DOMAIN CONTAINING PROTEIN 1 UBAP1-MVB12-ASSOCIATED (UMA)-DOMAIN CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000003867.4|UniProtKB=F7DTP3 F7DTP3 PALMD PTHR46881:SF1 PALMDELPHIN PALMDELPHIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000047561.1|UniProtKB=A0A5F8GT40 A0A5F8GT40 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000006624.3|UniProtKB=A0A5F8H9H4 A0A5F8H9H4 FBLN7 PTHR24034:SF94 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBULIN-7 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000014795.4|UniProtKB=F7E6F4 F7E6F4 PTHR13832:SF837 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 2C-LIKE DOMAIN-CONTAINING PROTEIN 1 phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000004451.4|UniProtKB=A0A5F8GXW2 A0A5F8GXW2 SMARCD3 PTHR13844:SF5 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 3 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000048359.1|UniProtKB=A0A5F8GXY2 A0A5F8GXY2 PTHR48083:SF6 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED ACYL-COA DEHYDROGENASE 6 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000047471.1|UniProtKB=A0A5F8GC84 A0A5F8GC84 C17orf67 PTHR48415:SF1 GENE 525-RELATED C17ORF67 HOMOLOG MONDO|Ensembl=ENSMODG00000001580.3|UniProtKB=F7BWX3 F7BWX3 MFSD11 PTHR23294:SF0 ET TRANSLATION PRODUCT-RELATED UNC93-LIKE PROTEIN MFSD11 MONDO|Ensembl=ENSMODG00000045687.1|UniProtKB=H9H9R0 H9H9R0 LOC130458967 PTHR26453:SF238 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10N1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006046.5|UniProtKB=A0A5F8GYY2 A0A5F8GYY2 FHOD1 PTHR45920:SF2 FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I FH1_FH2 DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 regulation of actin filament bundle assembly#GO:0032231;cellular component organization#GO:0016043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;positive regulation of cellular component organization#GO:0051130;actin filament-based process#GO:0030029;positive regulation of organelle organization#GO:0010638;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of cellular component biogenesis#GO:0044089;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;positive regulation of actin filament bundle assembly#GO:0032233;actin filament organization#GO:0007015 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000051238.1|UniProtKB=A0A5F8HF80 A0A5F8HF80 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015773.4|UniProtKB=F6ZS82 F6ZS82 CIB4 PTHR45791:SF4 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 4 cation binding#GO:0043169;magnesium ion binding#GO:0000287;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 MONDO|Ensembl=ENSMODG00000019699.3|UniProtKB=F6TCH9 F6TCH9 CCNB1 PTHR10177:SF193 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B1 enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;chromosome localization#GO:0050000;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;mitotic metaphase chromosome alignment#GO:0007080;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;mitotic cell cycle phase transition#GO:0044772;nuclear division#GO:0000280;organelle localization#GO:0051640;localization#GO:0051179;organelle fission#GO:0048285 protein kinase complex#GO:1902911;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739 kinase activator#PC00138 p53 pathway#P00059>Cyclin B#P04614;Cell cycle#P00013>Cyclin B#P00486 MONDO|Ensembl=ENSMODG00000029483.2|UniProtKB=K7E2U0 K7E2U0 PTHR10331:SF25 T COMPLEX PROTEIN 10 T-COMPLEX PROTEIN 10A-RELATED binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;microtubule organizing center organization#GO:0031023;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cilium assembly#GO:0060271;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;organelle assembly#GO:0070925;centriole replication#GO:0007099 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000008947.4|UniProtKB=F7GD11 F7GD11 INTS1 PTHR21224:SF1 INTEGRATOR COMPLEX SUBUNIT 1 INTEGRATOR COMPLEX SUBUNIT 1 nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;DNA-templated transcription#GO:0006351;catabolic process#GO:0009056;DNA-templated transcription initiation#GO:0006352;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;integrator complex#GO:0032039;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000048221.1|UniProtKB=A0A5F8GNR2 A0A5F8GNR2 LOC100010078 PTHR35252:SF1 RETINITIS PIGMENTOSA 9 PROTEIN RETINITIS PIGMENTOSA 9 PROTEIN MONDO|Ensembl=ENSMODG00000011245.3|UniProtKB=F6RMS8 F6RMS8 DCAKD PTHR10695:SF46 DEPHOSPHO-COA KINASE-RELATED DEPHOSPHO-COA KINASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293 kinase#PC00137;metabolite interconversion enzyme#PC00262 Coenzyme A biosynthesis#P02736>Pantetheine-phosphate adenyltransferase#P02886;Coenzyme A biosynthesis#P02736>Dephospho-CoA kinase#P02884 MONDO|Ensembl=ENSMODG00000001068.4|UniProtKB=F6YQK1 F6YQK1 ZFAT PTHR24388:SF73 ZINC FINGER PROTEIN ZINC FINGER PROTEIN ZFAT sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000016352.2|UniProtKB=F7F775 F7F775 NDUFAB1 PTHR20863:SF80 ACYL CARRIER PROTEIN ACYL CARRIER PROTEIN, MITOCHONDRIAL small molecule binding#GO:0036094;binding#GO:0005488;molecular carrier activity#GO:0140104 mitochondrion#GO:0005739;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;respiratory chain complex I#GO:0045271;transporter complex#GO:1990351 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000000209.4|UniProtKB=F6VWS6 F6VWS6 TBC1D9 PTHR22957:SF536 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 9 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000011079.4|UniProtKB=F6XJP0 F6XJP0 FNDC3A PTHR24099:SF9 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 3A anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;spermatid differentiation#GO:0048515;sexual reproduction#GO:0019953;spermatid development#GO:0007286;cell differentiation#GO:0030154;gamete generation#GO:0007276;reproductive process#GO:0022414;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;male gamete generation#GO:0048232;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000003691.3|UniProtKB=F7FAH7 F7FAH7 PTHR43943:SF8 DEHYDROGENASE/REDUCTASE (SDR FAMILY) MEMBER 4 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 4-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000036794.1|UniProtKB=A0A5F8HB05 A0A5F8HB05 ZNF629 PTHR24376:SF78 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 629 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000039477.1|UniProtKB=A0A5F8GWD5 A0A5F8GWD5 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000004446.5|UniProtKB=F6Y8C8 F6Y8C8 TNN PTHR19143:SF348 FIBRINOGEN/TENASCIN/ANGIOPOEITIN TENASCIN-N protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;signaling receptor binding#GO:0005102;binding#GO:0005488 cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;developmental growth involved in morphogenesis#GO:0060560;neuron projection extension#GO:1990138;animal gross anatomical part developmental process#GO:0160108;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;generation of neurons#GO:0048699;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;cell growth#GO:0016049;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;growth#GO:0040007;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;developmental cell growth#GO:0048588;anatomical structure development#GO:0048856;cell-substrate adhesion#GO:0031589;system development#GO:0048731;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;developmental growth#GO:0048589;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000010674.4|UniProtKB=F7CJE2 F7CJE2 ZSWIM2 PTHR21540:SF3 RING FINGER AND SWIM DOMAIN-CONTAINING PROTEIN 2 E3 UBIQUITIN-PROTEIN LIGASE ZSWIM2 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000020201.4|UniProtKB=F7G829 F7G829 PATL1 PTHR21551:SF2 TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1 PROTEIN PAT1 HOMOLOG 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;negative regulation of translation#GO:0017148;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;cellular component organization or biogenesis#GO:0071840;regulation of mRNA metabolic process#GO:1903311;primary metabolic process#GO:0044238;P-body assembly#GO:0033962;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of protein metabolic process#GO:0051248;positive regulation of RNA metabolic process#GO:0051254;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;RNA decapping#GO:0110154;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;cellular component assembly#GO:0022607;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;catabolic process#GO:0009056;organelle assembly#GO:0070925;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound metabolic process#GO:0006139;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of gene expression#GO:0010468 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000020507.4|UniProtKB=F7EPF4 F7EPF4 RLIG1 PTHR31219:SF2 CHROMOSOME 28 C12ORF29 HOMOLOG RNA LIGASE 1 MONDO|Ensembl=ENSMODG00000004639.4|UniProtKB=F6UNG8 F6UNG8 SLC25A4 PTHR45635:SF32 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE 1 antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;purine nucleotide transmembrane transporter activity#GO:0015216;active transmembrane transporter activity#GO:0022804;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505 cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nitrogen compound transport#GO:0071705;biological regulation#GO:0065007;regulation of mitochondrial membrane permeability#GO:0046902;organophosphate ester transport#GO:0015748;regulation of membrane permeability#GO:0090559;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000028182.2|UniProtKB=K7E6D1 K7E6D1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000011755.4|UniProtKB=F7CWI4 F7CWI4 LOC100027243 PTHR23427:SF14 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 4 Golgi organization#GO:0007030;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000047799.1|UniProtKB=A0A5F8H1M1 A0A5F8H1M1 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000023282.2|UniProtKB=F6SDY0 F6SDY0 CYSRT1 PTHR37879:SF1 CYSTEINE-RICH TAIL PROTEIN 1 CYSTEINE-RICH TAIL PROTEIN 1 MONDO|Ensembl=ENSMODG00000009951.4|UniProtKB=A0A5F8HIT6 A0A5F8HIT6 BBS4 PTHR44186:SF1 FAMILY NOT NAMED BBSOME COMPLEX MEMBER BBS4 MONDO|Ensembl=ENSMODG00000007984.4|UniProtKB=K7E561 K7E561 POLR2G PTHR12709:SF4 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000024054.4|UniProtKB=A0A5F8GFL3 A0A5F8GFL3 UBTF PTHR46318:SF3 UPSTREAM BINDING TRANSCRIPTION FACTOR NUCLEOLAR TRANSCRIPTION FACTOR 1 nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;core promoter sequence-specific DNA binding#GO:0001046;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of transcription by RNA polymerase I#GO:0006356;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;DNA-templated transcription#GO:0006351;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;transcription by RNA polymerase I#GO:0006360;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase I#GO:0045943;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 General transcription by RNA polymerase I#P00022>UBF1#P00655 MONDO|Ensembl=ENSMODG00000049403.1|UniProtKB=A0A5F8HFQ8 A0A5F8HFQ8 CIMIP5 PTHR31909:SF2 CHROMOSOME 20 ORF85 FAMILY MEMBER CILIARY MICROTUBULE INNER PROTEIN 5 MONDO|Ensembl=ENSMODG00000040272.1|UniProtKB=A0A5F8HBL8 A0A5F8HBL8 GPR162 PTHR16518:SF6 G-PROTEIN COUPLED RECEPTOR 153, 162 G PROTEIN-COUPLED RECEPTOR 162-RELATED transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000047740.1|UniProtKB=A0A5F8GPG6 A0A5F8GPG6 PTHR13082:SF0 SAP18 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 Hedgehog signaling pathway#P00025>Sap18#P00697 MONDO|Ensembl=ENSMODG00000003150.4|UniProtKB=F6WE42 F6WE42 ACOX3 PTHR10909:SF390 ELECTRON TRANSPORT OXIDOREDUCTASE PEROXISOMAL ACYL-COENZYME A OXIDASE 3 heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;fatty acid binding#GO:0005504;lipid binding#GO:0008289;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;organic acid binding#GO:0043177 fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;peroxisome#GO:0005777;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000011369.4|UniProtKB=F6SPX0 F6SPX0 SLC6A20 PTHR11616:SF44 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT TRANSPORTER XTRP3 carboxylic acid transmembrane transporter activity#GO:0046943;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;sodium ion transport#GO:0006814;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;monoatomic ion transport#GO:0006811;glycine transport#GO:0015816;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;amino acid transport#GO:0006865;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 MONDO|Ensembl=ENSMODG00000005645.4|UniProtKB=F7BWA4 F7BWA4 ERMARD PTHR31701:SF2 ENDOPLASMIC RETICULUM MEMBRANE-ASSOCIATED RNA DEGRADATION PROTEIN ENDOPLASMIC RETICULUM MEMBRANE-ASSOCIATED RNA DEGRADATION PROTEIN animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neuron migration#GO:0001764;neurogenesis#GO:0022008;system development#GO:0048731;cellular process#GO:0009987;cell migration#GO:0016477;multicellular organismal process#GO:0032501;cell motility#GO:0048870;cell differentiation#GO:0030154;nervous system development#GO:0007399 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000019187.5|UniProtKB=F7FMA0 F7FMA0 C17orf75 PTHR14416:SF2 PROTEIN NJMU-R1 PROTEIN NJMU-R1 Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000023936.3|UniProtKB=F6ZRZ5 F6ZRZ5 PTHR11716:SF9 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2, MEMBRANE ASSOCIATED cation binding#GO:0043169;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;ion binding#GO:0043167;small molecule binding#GO:0036094;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phospholipid binding#GO:0005543;lipid binding#GO:0008289;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;A2-type glycerophospholipase activity#GO:0004623;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620 lipid metabolic process#GO:0006629;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;negative regulation of cell activation#GO:0050866;organophosphate metabolic process#GO:0019637;negative regulation of cell population proliferation#GO:0008285;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of cell adhesion#GO:0007162;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;negative regulation of multicellular organismal process#GO:0051241;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of T cell proliferation#GO:0042129;phosphatidylglycerol metabolic process#GO:0046471;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;metabolic process#GO:0008152;negative regulation of T cell proliferation#GO:0042130;regulation of leukocyte proliferation#GO:0070663;cellular process#GO:0009987;regulation of mononuclear cell proliferation#GO:0032944;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell-cell adhesion#GO:0022408;glycerophospholipid metabolic process#GO:0006650;phosphatidylcholine metabolic process#GO:0046470;regulation of T cell activation#GO:0050863;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;phosphorus metabolic process#GO:0006793;regulation of lymphocyte activation#GO:0051249;glycerolipid metabolic process#GO:0046486 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000006438.4|UniProtKB=F7EYW1 F7EYW1 AJAP1 PTHR32422:SF0 ADHERENS JUNCTION-ASSOCIATED PROTEIN 1 ADHERENS JUNCTION-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488 cytoplasmic side of membrane#GO:0098562;anchoring junction#GO:0070161;cell-cell contact zone#GO:0044291;adherens junction#GO:0005912;side of membrane#GO:0098552;cell junction#GO:0030054;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000019477.3|UniProtKB=F6RB74 F6RB74 XKR7 PTHR16024:SF7 XK-RELATED PROTEIN XK-RELATED PROTEIN 7 macromolecule localization#GO:0033036;lipid transport#GO:0006869;membrane organization#GO:0061024;phospholipid transport#GO:0015914;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;phagocytosis#GO:0006909;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;programmed cell death#GO:0012501;cell death#GO:0008219;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;anatomical structure development#GO:0048856;localization#GO:0051179;cellular process#GO:0009987;endomembrane system organization#GO:0010256;membrane invagination#GO:0010324;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277;cellular component organization#GO:0016043;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;endocytosis#GO:0006897;lipid localization#GO:0010876;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000014581.5|UniProtKB=F7ASB6 F7ASB6 AKAP8L PTHR12190:SF4 A-KINASE ANCHOR PROTEIN AKAP 8 A-KINASE ANCHOR PROTEIN 8-LIKE protein binding#GO:0005515;binding#GO:0005488;protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237 organelle fission#GO:0048285;mitotic chromosome condensation#GO:0007076;chromosome condensation#GO:0030261;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;chromosome segregation#GO:0007059;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014582.4|UniProtKB=A0A5F8HEJ4 A0A5F8HEJ4 ANKRD28 PTHR24123:SF75 ANKYRIN REPEAT-CONTAINING SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY ANKYRIN REPEAT SUBUNIT A phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular component biogenesis#GO:0044089;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;regulation of cell junction assembly#GO:1901888;positive regulation of cellular component organization#GO:0051130;regulation of cell-matrix adhesion#GO:0001952 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000003899.3|UniProtKB=F7D857 F7D857 EIF4E3 PTHR11960:SF66 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3 translation initiation factor activity#GO:0003743;RNA binding#GO:0003723;translation factor activity#GO:0180051;binding#GO:0005488;nucleic acid binding#GO:0003676 translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000008365.4|UniProtKB=F7E484 F7E484 CGNL1 PTHR46349:SF2 CINGULIN-LIKE PROTEIN 1-RELATED CINGULIN-LIKE PROTEIN 1 localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to cell junction#GO:1902414;macromolecule localization#GO:0033036 cell-cell junction#GO:0005911;apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000006492.4|UniProtKB=F7F2F7 F7F2F7 DFFB PTHR13067:SF2 CASPASE-ACTIVATED DNASE DNAATION FACTOR-RELATED PROTEIN 4 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;nuclease activity#GO:0004518 cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;catabolic process#GO:0009056;nucleic acid metabolic process#GO:0090304;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;apoptotic process#GO:0006915;cell death#GO:0008219;execution phase of apoptosis#GO:0097194;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>CAD#P00618 MONDO|Ensembl=ENSMODG00000024425.2|UniProtKB=F7FUP6 F7FUP6 PTHR21622:SF0 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;mitochondrial protein import pathway#GO:7770058;gene expression#GO:0010467;protein maturation#GO:0051604;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;primary metabolic process#GO:0044238;mitochondrial transport#GO:0006839;localization#GO:0051179;protein metabolic process#GO:0019538;cellular localization#GO:0051641 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 MONDO|Ensembl=ENSMODG00000000644.4|UniProtKB=F6SUR6 F6SUR6 PRPF38A PTHR23142:SF1 PRE-MRNA-SPLICING FACTOR 38A-RELATED PRE-MRNA-SPLICING FACTOR 38A gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000004734.3|UniProtKB=F6Y1B2 F6Y1B2 PAK5 PTHR48015:SF27 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE PAK 5 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;cellular response to nutrient levels#GO:0031669;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;signal transduction#GO:0007165;cellular process#GO:0009987;response to nutrient levels#GO:0031667;response to stress#GO:0006950 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837 MONDO|Ensembl=ENSMODG00000009621.4|UniProtKB=A0A5F8HC41 A0A5F8HC41 DCAF8 PTHR15574:SF21 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1 AND CUL4 ASSOCIATED FACTOR 8 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000014859.4|UniProtKB=F7BYL2 F7BYL2 CAVIN1 PTHR15240:SF3 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;transcription by RNA polymerase I#GO:0006360;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;transcription initiation at RNA polymerase I promoter#GO:0006361 cell periphery#GO:0071944;caveola#GO:0005901;membrane raft#GO:0045121;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;membrane microdomain#GO:0098857;intracellular anatomical structure#GO:0005622;plasma membrane raft#GO:0044853 membrane traffic protein#PC00150 General transcription by RNA polymerase I#P00022>PTRF#P00656 MONDO|Ensembl=ENSMODG00000005485.4|UniProtKB=F7CFZ3 F7CFZ3 LOC100010647 PTHR19143:SF263 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN-LIKE PROTEIN 1 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 negative regulation of cell activation#GO:0050866;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of cell adhesion#GO:0007162;negative regulation of cell-cell adhesion#GO:0022408;regulation of T cell activation#GO:0050863;regulation of cell adhesion#GO:0030155;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;negative regulation of lymphocyte activation#GO:0051250;negative regulation of leukocyte activation#GO:0002695;regulation of immune response#GO:0050776;negative regulation of T cell activation#GO:0050868;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of lymphocyte activation#GO:0051249;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000039617.1|UniProtKB=A0A5F8GG13 A0A5F8GG13 LOC100022003 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023561.3|UniProtKB=A0A5F8G719 A0A5F8G719 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000036722.1|UniProtKB=F7E687 F7E687 LOC100020819 PTHR26450:SF38 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR FAMILY 52 SUBFAMILY S MEMBER 6 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017423.4|UniProtKB=F7AIU0 F7AIU0 LOC100013639 PTHR10880:SF48 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000031755.2|UniProtKB=A0A5F8GK55 A0A5F8GK55 PTHR22435:SF0 CHROMOSOME 6 OPEN READING FRAME 222 PROTEIN BNIP5 MONDO|Ensembl=ENSMODG00000018841.2|UniProtKB=F7EDT9 F7EDT9 LYSMD1 PTHR20932:SF2 LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 1-RELATED MONDO|Ensembl=ENSMODG00000023111.2|UniProtKB=Q2AB97 Q2AB97 T2R22 PTHR11394:SF58 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 7 transmembrane signaling receptor activity#GO:0004888;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089 sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007552.4|UniProtKB=F7G0H2 F7G0H2 HMX3 PTHR46110:SF2 HOMEOBOX PROTEIN HMX HOMEOBOX PROTEIN HMX3 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000013401.5|UniProtKB=F6UYJ2 F6UYJ2 IP6K2 PTHR12400:SF47 INOSITOL POLYPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE KINASE 2 phosphotransferase activity, phosphate group as acceptor#GO:0016776;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 kinase#PC00137 MONDO|Ensembl=ENSMODG00000043386.1|UniProtKB=A0A5F8H297 A0A5F8H297 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000020324.4|UniProtKB=F7G7B8 F7G7B8 MS4A1 PTHR23320:SF79 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED B-LYMPHOCYTE ANTIGEN CD20 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transporter#PC00227 MONDO|Ensembl=ENSMODG00000019467.3|UniProtKB=A0A5F8GCI1 A0A5F8GCI1 ARL15 PTHR46693:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 15 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 15 MONDO|Ensembl=ENSMODG00000004288.4|UniProtKB=F6SY45 F6SY45 RRP15 PTHR13245:SF14 RRP15-LIKE PROTEIN RRP15-LIKE PROTEIN primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 MONDO|Ensembl=ENSMODG00000004036.4|UniProtKB=A0A5F8G8G5 A0A5F8G8G5 SMC2 PTHR43941:SF15 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2 chromatin binding#GO:0003682;binding#GO:0005488 mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;mitotic chromosome condensation#GO:0007076;chromosome condensation#GO:0030261;organelle fission#GO:0048285;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensin complex#GO:0000796;condensed chromosome#GO:0000793 MONDO|Ensembl=ENSMODG00000000926.4|UniProtKB=F6UU29 F6UU29 RADIL PTHR16027:SF3 DILUTE DOMAIN-CONTAINING PROTEIN YPR089W RAS-ASSOCIATING AND DILUTE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 cell migration#GO:0016477;neural crest cell development#GO:0014032;tissue development#GO:0009888;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;cellular process#GO:0009987;animal organ development#GO:0048513;cellular developmental process#GO:0048869;mesenchyme development#GO:0060485;mesenchymal cell differentiation#GO:0048762;developmental process#GO:0032502;neural crest cell differentiation#GO:0014033;substrate adhesion-dependent cell spreading#GO:0034446;cell motility#GO:0048870;cell differentiation#GO:0030154;cell development#GO:0048468;anatomical structure development#GO:0048856;cell-substrate adhesion#GO:0031589;animal gross anatomical part developmental process#GO:0160108;stem cell development#GO:0048864;cell adhesion#GO:0007155 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 MONDO|Ensembl=ENSMODG00000017684.4|UniProtKB=F7G5Q1 F7G5Q1 TERB2 PTHR35345:SF1 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 2 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 2 chromosome localization#GO:0050000;homologous chromosome pairing at meiosis#GO:0007129;cellular process#GO:0009987;organelle organization#GO:0006996;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;reproductive process#GO:0022414;cell cycle process#GO:0022402;cell cycle#GO:0007049;telomere localization#GO:0034397;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;localization#GO:0051179;organelle fission#GO:0048285;sexual reproduction#GO:0019953;telomere tethering at nuclear periphery#GO:0034398;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;organelle localization#GO:0051640 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;nuclear membrane#GO:0031965;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;organelle inner membrane#GO:0019866;nucleus#GO:0005634;membrane#GO:0016020;organelle envelope#GO:0031967 MONDO|Ensembl=ENSMODG00000013134.4|UniProtKB=F7B035 F7B035 ARHGEF12 PTHR45872:SF3 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 12 guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;signaling receptor binding#GO:0005102;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000018520.4|UniProtKB=F7AG87 F7AG87 CD109 PTHR11412:SF136 MACROGLOBULIN / COMPLEMENT CD109 ANTIGEN enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;catalytic complex#GO:1902494;extracellular protein-containing complex#GO:0140392 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000009992.4|UniProtKB=F6USP2 F6USP2 VTI1B PTHR21230:SF89 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1B binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;SNAP receptor activity#GO:0005484;protein binding#GO:0005515 post-Golgi vesicle-mediated transport#GO:0006892;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;cellular component organization#GO:0016043;cytosolic transport#GO:0016482;Golgi vesicle transport#GO:0048193;metabolic process#GO:0008152;endosomal transport#GO:0016197;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;cellular process#GO:0009987;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;localization#GO:0051179;Golgi to vacuole transport#GO:0006896;Golgi organization#GO:0007030;intra-Golgi vesicle-mediated transport#GO:0006891;vesicle fusion#GO:0006906;catabolic process#GO:0009056;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;establishment of localization#GO:0051234;retrograde transport, endosome to Golgi#GO:0042147;membrane fusion#GO:0061025;membrane organization#GO:0061024;macroautophagy#GO:0016236 late endosome membrane#GO:0031902;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasm#GO:0005737;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;intracellular vesicle#GO:0097708;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;coated vesicle membrane#GO:0030662;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;ER to Golgi transport vesicle membrane#GO:0012507;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;endoplasmic reticulum subcompartment#GO:0098827;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;vesicle#GO:0031982;SNARE complex#GO:0031201;intracellular membrane-bounded organelle#GO:0043231 SNARE protein#PC00034;membrane traffic protein#PC00150 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072 MONDO|Ensembl=ENSMODG00000039319.1|UniProtKB=A0A5F8HLA0 A0A5F8HLA0 MPC2 PTHR14154:SF154 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER 2 transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 carboxylic acid transport#GO:0046942;transport#GO:0006810;mitochondrial transmembrane transport#GO:1990542;organic acid transport#GO:0015849;intracellular transport#GO:0046907;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839 inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000000111.4|UniProtKB=F6YC25 F6YC25 RPAP1 PTHR21483:SF18 RNA POLYMERASE II-ASSOCIATED PROTEIN 1 RNA POLYMERASE II-ASSOCIATED PROTEIN 1 MONDO|Ensembl=ENSMODG00000048980.1|UniProtKB=F6T7G9 F6T7G9 LOC100619512 PTHR26452:SF930 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048728.1|UniProtKB=A0A5F8GPD2 A0A5F8GPD2 monDomV1R1230 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000044460.1|UniProtKB=A0A5F8H4I9 A0A5F8H4I9 LOC100013386 PTHR48002:SF113 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002093.4|UniProtKB=F6UHE2 F6UHE2 PTHR12011:SF305 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G7 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000041986.1|UniProtKB=A0A5F8G261 A0A5F8G261 PTHR23262:SF248 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-6 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000042099.1|UniProtKB=A0A5F8H083 A0A5F8H083 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024588.2|UniProtKB=F6PFW3 F6PFW3 LOC100009865 PTHR19282:SF163 TETRASPANIN CD9 ANTIGEN cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005395.3|UniProtKB=A0A5F8HBH8 A0A5F8HBH8 CHRNE PTHR18945:SF59 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT EPSILON ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230 cellular response to chemical stimulus#GO:0070887;nervous system process#GO:0050877;response to oxygen-containing compound#GO:1901700;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;regulation of biological process#GO:0050789;muscle system process#GO:0003012;response to stimulus#GO:0050896;skeletal muscle contraction#GO:0003009;signaling#GO:0023052;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;trans-synaptic signaling#GO:0099537;neuromuscular process#GO:0050905;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;transport#GO:0006810;muscle contraction#GO:0006936;establishment of localization#GO:0051234;system process#GO:0003008;acetylcholine receptor signaling pathway#GO:0095500;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 MONDO|Ensembl=ENSMODG00000019352.5|UniProtKB=H9H7C2 H9H7C2 USP30 PTHR24006:SF888 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30 catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000038209.1|UniProtKB=A0A5F8G399 A0A5F8G399 RYBP PTHR12920:SF3 RYBP AND YAF2-RELATED RING1 AND YY1-BINDING PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transcription cofactor#PC00217 MONDO|Gene=MT-CYB|UniProtKB=Q04911 Q04911 MT-CYB PTHR19271:SF42 CYTOCHROME B CYTOCHROME B monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055;oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075 electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex III#GO:0045275;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069 MONDO|Ensembl=ENSMODG00000021157.4|UniProtKB=F6QBP6 F6QBP6 KANSL2 PTHR13453:SF1 KAT8 REGULATORY NSL COMPLEX SUBUNIT 2 KAT8 REGULATORY NSL COMPLEX SUBUNIT 2 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;chromatin#GO:0000785;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;NSL complex#GO:0044545;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000010750.4|UniProtKB=F7FWJ1 F7FWJ1 PTHR23055:SF67 CALCIUM BINDING PROTEINS RIKEN CDNA 1700109H08 GENE calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000006805.4|UniProtKB=F6PGS0 F6PGS0 HNF4G PTHR24083:SF42 NUCLEAR HORMONE RECEPTOR HEPATOCYTE NUCLEAR FACTOR 4-GAMMA transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000008484.3|UniProtKB=A0A5F8H3K1 A0A5F8H3K1 ITPRIPL1 PTHR10656:SF40 CELL FATE DETERMINING PROTEIN MAB21-RELATED INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-INTERACTING PROTEIN-LIKE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;membrane#GO:0016020 nucleotidyltransferase#PC00174;transferase#PC00220 MONDO|Ensembl=ENSMODG00000015461.4|UniProtKB=F6S3L1 F6S3L1 AASS PTHR11133:SF28 SACCHAROPINE DEHYDROGENASE ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000014650.4|UniProtKB=A0A5F8GGT5 A0A5F8GGT5 FSD1L PTHR24099:SF8 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FSD1-LIKE PROTEIN ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000008269.4|UniProtKB=A0A5F8GG89 A0A5F8GG89 DOCK9 PTHR23317:SF77 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 9 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000025656.2|UniProtKB=F6XDT8 F6XDT8 PTHR17534:SF4 OX40 LIGAND TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 4 tumor necrosis factor receptor superfamily binding#GO:0032813;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102 positive regulation of cell adhesion#GO:0045785;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255;regulation of T cell proliferation#GO:0042129;inflammatory response#GO:0006954;positive regulation of lymphocyte proliferation#GO:0050671;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;positive regulation of lymphocyte activation#GO:0051251;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;positive regulation of leukocyte proliferation#GO:0070665;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of gene expression#GO:0010468;defense response#GO:0006952;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;regulation of leukocyte activation#GO:0002694;regulation of lymphocyte activation#GO:0051249;positive regulation of T cell proliferation#GO:0042102;response to stimulus#GO:0050896;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of cell-cell adhesion#GO:0022409;regulation of multicellular organismal process#GO:0051239;regulation of T cell activation#GO:0050863;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of T cell activation#GO:0050870;positive regulation of leukocyte activation#GO:0002696;positive regulation of mononuclear cell proliferation#GO:0032946;regulation of leukocyte proliferation#GO:0070663 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000000227.4|UniProtKB=F6SYP1 F6SYP1 SLMAP PTHR15715:SF22 CENTROSOMAL PROTEIN OF 170 KDA SARCOLEMMAL MEMBRANE-ASSOCIATED PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of hippo signaling#GO:0035331;regulation of biological quality#GO:0065008;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of membrane potential#GO:0042391;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000048663.1|UniProtKB=A0A5F8GMI5 A0A5F8GMI5 PTHR24381:SF27 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 180 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000003252.4|UniProtKB=F6T1N6 F6T1N6 PTHR11258:SF13 2-5 OLIGOADENYLATE SYNTHETASE 2'-5'-OLIGOADENYLATE SYNTHASE 1 double-stranded RNA binding#GO:0003725;adenylyltransferase activity#GO:0070566;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to cytokine#GO:0034097;response to chemical#GO:0042221;defense response to other organism#GO:0098542;cell surface receptor signaling pathway#GO:0007166;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;response to peptide#GO:1901652;immune response#GO:0006955;biological regulation#GO:0065007;response to other organism#GO:0051707;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;antiviral innate immune response#GO:0140374;cellular response to stimulus#GO:0051716;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;response to virus#GO:0009615 organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;membrane#GO:0016020;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;nucleotidyltransferase#PC00174 MONDO|Ensembl=ENSMODG00000000479.4|UniProtKB=A0A5F8HFA0 A0A5F8HFA0 SLC9A7 PTHR10110:SF62 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 7 potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;import across plasma membrane#GO:0098739;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000021234.4|UniProtKB=F6U0I3 F6U0I3 TFDP2 PTHR12548:SF5 TRANSCRIPTION FACTOR DP TRANSCRIPTION FACTOR DP-2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000037224.1|UniProtKB=A0A5F8HEI3 A0A5F8HEI3 BCL10 PTHR34920:SF1 B-CELL LYMPHOMA/LEUKEMIA 10 B-CELL LYMPHOMA_LEUKEMIA 10 enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;transcription coactivator activity#GO:0003713;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;kinase binding#GO:0019900;binding#GO:0005488;molecular function activator activity#GO:0140677;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription coregulator activity#GO:0003712;transcription factor binding#GO:0008134;molecular function regulator activity#GO:0098772;kinase activator activity#GO:0019209 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;immune system process#GO:0002376;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of programmed cell death#GO:0043067;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;adaptive immune response#GO:0002250;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;immune response#GO:0006955 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000007901.3|UniProtKB=F6YSK2 F6YSK2 PTHR10339:SF24 ADP-RIBOSYLTRANSFERASE T-CELL ECTO-ADP-RIBOSYLTRANSFERASE 1-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 transferase#PC00220 MONDO|Ensembl=ENSMODG00000039931.1|UniProtKB=A0A5F8G903 A0A5F8G903 PTHR26453:SF607 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2AG2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016872.2|UniProtKB=F6Y217 F6Y217 TSACC PTHR37368:SF1 TSSK6-ACTIVATING CO-CHAPERONE PROTEIN TSSK6-ACTIVATING CO-CHAPERONE PROTEIN binding#GO:0005488;protein-folding chaperone binding#GO:0051087;protein binding#GO:0005515 positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of metabolic process#GO:0009893 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein folding chaperone complex#GO:0101031 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000000989.3|UniProtKB=F7ES17 F7ES17 MCM6 PTHR11630:SF73 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM6 helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697 nuclear DNA replication#GO:0033260;mitotic DNA replication#GO:1902969;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cell cycle DNA replication#GO:0044786;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;mitotic cell cycle process#GO:1903047;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;MCM complex#GO:0042555;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000013121.5|UniProtKB=A0A5F8HB51 A0A5F8HB51 BRD3 PTHR22880:SF246 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN-CONTAINING PROTEIN 3 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000013024.4|UniProtKB=F7BP31 F7BP31 SORL1 PTHR12106:SF50 SORTILIN RELATED SORTILIN-RELATED RECEPTOR protein localization to vacuole#GO:0072665;lysosomal transport#GO:0007041;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;protein localization to lysosome#GO:0061462;protein localization to organelle#GO:0033365;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;intracellular transport#GO:0046907;protein localization to Golgi apparatus#GO:0034067;intracellular protein transport#GO:0006886;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000010128.1|UniProtKB=F6WNJ3 F6WNJ3 SMIM19 PTHR31888:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 19 SMALL INTEGRAL MEMBRANE PROTEIN 19 MONDO|Ensembl=ENSMODG00000015824.4|UniProtKB=F7FDX1 F7FDX1 KIF3C PTHR24115:SF734 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3C ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;microtubule-based movement#GO:0007018;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000040453.1|UniProtKB=F6QLD9 F6QLD9 LOC100013975 PTHR48001:SF39 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023369.3|UniProtKB=A0A5F8G741 A0A5F8G741 SLC31A1 PTHR12483:SF22 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS HIGH AFFINITY COPPER UPTAKE PROTEIN 1 transition metal ion transmembrane transporter activity#GO:0046915;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810;transition metal ion transport#GO:0000041;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;copper ion transmembrane transport#GO:0035434;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000025483.3|UniProtKB=A0A5F8G3D7 A0A5F8G3D7 PTHR22529:SF1 EPITHELIAL-STROMAL INTERACTION PROTEIN 1 EPITHELIAL-STROMAL INTERACTION PROTEIN 1 immune system process#GO:0002376;cell activation#GO:0001775;inflammatory response#GO:0006954;macrophage activation#GO:0042116;defense response#GO:0006952;response to stress#GO:0006950;leukocyte activation#GO:0045321;cellular process#GO:0009987;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;myeloid leukocyte activation#GO:0002274 MONDO|Ensembl=ENSMODG00000040057.1|UniProtKB=A0A5F8GMU4 A0A5F8GMU4 PTHR37680:SF1 C130050O18RIK PROTEIN C130050O18RIK PROTEIN MONDO|Ensembl=ENSMODG00000038162.1|UniProtKB=A0A5F8HJ90 A0A5F8HJ90 TAAR8 PTHR24249:SF271 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 6 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000019828.4|UniProtKB=H9H7H8 H9H7H8 LSG1 PTHR45709:SF6 LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED LARGE SUBUNIT GTPASE 1 HOMOLOG hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle localization#GO:0051640;ribosome biogenesis#GO:0042254;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000019371.5|UniProtKB=F7AXA6 F7AXA6 WHAMM PTHR23330:SF6 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED WASP HOMOLOG-ASSOCIATED PROTEIN WITH ACTIN, MEMBRANES AND MICROTUBULES binding#GO:0005488;protein-containing complex binding#GO:0044877 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;supramolecular fiber organization#GO:0097435;cellular localization#GO:0051641;localization#GO:0051179;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cellular component organization#GO:0016043;actin filament organization#GO:0007015;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000028628.2|UniProtKB=K7E2Q1 K7E2Q1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000023777.3|UniProtKB=F6RVP1 F6RVP1 PTHR14132:SF12 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA PHOSPHOLEMMAN transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of transmembrane transport#GO:0034762;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000015496.4|UniProtKB=F6WES7 F6WES7 KATNIP PTHR21534:SF0 KATANIN-INTERACTING PROTEIN KATANIN-INTERACTING PROTEIN MONDO|Ensembl=ENSMODG00000040380.1|UniProtKB=A0A5F8G208 A0A5F8G208 MTFP1 PTHR11001:SF2 MITOCHONDRIAL FISSION PROCESS PROTEIN 1 MITOCHONDRIAL FISSION PROCESS PROTEIN 1 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840;mitochondrial fission#GO:0000266;mitochondrion organization#GO:0007005 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000005628.4|UniProtKB=A0A5F8GBV6 A0A5F8GBV6 IFIH1 PTHR14074:SF14 HELICASE WITH DEATH DOMAIN-RELATED INTERFERON-INDUCED HELICASE C DOMAIN-CONTAINING PROTEIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;ion binding#GO:0043167;single-stranded RNA binding#GO:0003727;zinc ion binding#GO:0008270 immune system process#GO:0002376;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;defense response to virus#GO:0051607;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;intracellular signal transduction#GO:0035556;response to virus#GO:0009615;cell communication#GO:0007154;antiviral innate immune response#GO:0140374;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;regulation of response to biotic stimulus#GO:0002831;response to external biotic stimulus#GO:0043207;intracellular receptor signaling pathway#GO:0030522;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stress#GO:0080134;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;positive regulation of innate immune response#GO:0045089;immune response#GO:0006955;activation of innate immune response#GO:0002218;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000000417.3|UniProtKB=F6VAS4 F6VAS4 PTHR45739:SF5 MATRIX PROTEIN, PUTATIVE-RELATED FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 3 cell-substrate adhesion#GO:0031589;multicellular organismal-level homeostasis#GO:0048871;tissue homeostasis#GO:0001894;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;homeostatic process#GO:0042592;epithelial structure maintenance#GO:0010669;cellular process#GO:0009987 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000004899.4|UniProtKB=F7C211 F7C211 FGFR4 PTHR24416:SF343 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 4 catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transferase activity#GO:0016740;kinase activity#GO:0016301;signaling receptor activity#GO:0038023;fibroblast growth factor binding#GO:0017134;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515;protein kinase activity#GO:0004672 regulation of biosynthetic process#GO:0009889;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;response to fibroblast growth factor#GO:0071774;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;fibroblast growth factor receptor signaling pathway#GO:0008543;regulation of steroid biosynthetic process#GO:0050810;regulation of lipid biosynthetic process#GO:0046890;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of lipid metabolic process#GO:0019216;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;regulation of ERK1 and ERK2 cascade#GO:0070372;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636 MONDO|Ensembl=ENSMODG00000009119.4|UniProtKB=F7EYJ5 F7EYJ5 TMEM178A PTHR32005:SF4 TRANSMEMBRANE PROTEIN 178B-RELATED TRANSMEMBRANE PROTEIN 178A intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;regulation of cell differentiation#GO:0045595;chemical homeostasis#GO:0048878;negative regulation of cellular process#GO:0048523;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;regulation of cell development#GO:0060284;monoatomic ion homeostasis#GO:0050801;regulation of multicellular organismal process#GO:0051239;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;regulation of myeloid cell differentiation#GO:0045637;regulation of hemopoiesis#GO:1903706;regulation of multicellular organismal development#GO:2000026;regulation of cytosolic calcium ion concentration#GO:0051480;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of developmental process#GO:0050793;homeostatic process#GO:0042592;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000014318.4|UniProtKB=A0A5F8GAD4 A0A5F8GAD4 MON2 PTHR10663:SF333 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PROTEIN MON2 HOMOLOG localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;protein localization to vacuole#GO:0072665;establishment of protein localization to vacuole#GO:0072666;protein localization to organelle#GO:0033365;protein targeting#GO:0006605;cytosolic transport#GO:0016482;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;intracellular protein transport#GO:0006886;transport#GO:0006810;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;protein targeting to vacuole#GO:0006623;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;early endosome membrane#GO:0031901;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000045014.1|UniProtKB=K7E5J7 K7E5J7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000020778.4|UniProtKB=F6Z980 F6Z980 NKX6-1 PTHR24340:SF31 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-6.1 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000014910.4|UniProtKB=F7G653 F7G653 PRRT1 PTHR14948:SF21 NG5 PROLINE-RICH TRANSMEMBRANE PROTEIN 1 molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545 cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;cellular component organization#GO:0016043;synapse organization#GO:0050808;cellular process#GO:0009987 cell junction#GO:0030054;postsynaptic membrane#GO:0045211;synaptic membrane#GO:0097060;plasma membrane region#GO:0098590;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018800.4|UniProtKB=A0A5F8HLU9 A0A5F8HLU9 GCLC PTHR11164:SF0 GLUTAMATE CYSTEINE LIGASE GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;biosynthetic process#GO:0009058 catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262;ligase#PC00142 MONDO|Ensembl=ENSMODG00000011246.4|UniProtKB=F6RLN2 F6RLN2 CCNB3 PTHR10177:SF214 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B3 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772 cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000002106.4|UniProtKB=F6UGR6 F6UGR6 POMGNT1 PTHR46396:SF1 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1 glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000010761.3|UniProtKB=A0A5F8HKX1 A0A5F8HKX1 ASH2L PTHR10598:SF0 SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 SET1_ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000046028.1|UniProtKB=A0A5F8HF36 A0A5F8HF36 PTHR26453:SF156 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000046226.1|UniProtKB=A0A5F8GZV2 A0A5F8GZV2 PTHR23268:SF131 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 19 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000017393.5|UniProtKB=A0A5F8HHA7 A0A5F8HHA7 NHSL1 PTHR23039:SF3 NANCE-HORAN SYNDROME PROTEIN NHS-LIKE PROTEIN 1 MONDO|Ensembl=ENSMODG00000005711.4|UniProtKB=F6U3S9 F6U3S9 ASTN1 PTHR16592:SF8 ASTROTACTIN-1-LIKE ASTROTACTIN-1 cellular process#GO:0009987;cell-cell adhesion#GO:0098609;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell migration#GO:0016477;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cell motility#GO:0048870;generation of neurons#GO:0048699;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000004588.4|UniProtKB=H9H654 H9H654 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000040698.1|UniProtKB=A0A5F8HG86 A0A5F8HG86 LOC100618039 PTHR48002:SF21 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000046284.1|UniProtKB=F6ZH36 F6ZH36 LOC100023908 PTHR48018:SF109 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8U3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028708.2|UniProtKB=A0A5F8HDP8 A0A5F8HDP8 TRH PTHR17530:SF2 PRO-THYROTROPIN-RELEASING HORMONE PRO-THYROTROPIN-RELEASING HORMONE signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708 peptide hormone#PC00179 Thyrotropin-releasing hormone receptor signaling pathway#P04394>ProTRH (Pro Thyrotropin-releasing Hormone)#P04586;Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH#P04585 MONDO|Ensembl=ENSMODG00000000343.4|UniProtKB=A0A5F8H1I0 A0A5F8H1I0 ADPRM PTHR16509:SF1 FAMILY NOT NAMED MANGANESE-DEPENDENT ADP-RIBOSE_CDP-ALCOHOL DIPHOSPHATASE transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081 MONDO|Ensembl=ENSMODG00000040174.1|UniProtKB=A0A5F8HC71 A0A5F8HC71 ERI1 PTHR23044:SF77 3'-5' EXONUCLEASE ERI1-RELATED 3'-5' EXORIBONUCLEASE 1 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;positive regulation of biosynthetic process#GO:0009891;rRNA processing#GO:0006364;regulation of chromatin organization#GO:1902275;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of cellular component organization#GO:0051129;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of cellular component organization#GO:0051128;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 exoribonuclease#PC00099 MONDO|Ensembl=ENSMODG00000009462.4|UniProtKB=F7FZE4 F7FZE4 ZAR1L PTHR31054:SF5 ZYGOTE ARREST PROTEIN 1-LIKE ISOFORM X1 PROTEIN ZAR1-LIKE nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 negative regulation of translation#GO:0017148;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;oogenesis#GO:0048477;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;reproductive process#GO:0022414;negative regulation of protein metabolic process#GO:0051248;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;developmental process involved in reproduction#GO:0003006;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cell maturation#GO:0048469;developmental process#GO:0032502;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;developmental maturation#GO:0021700;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000029102.2|UniProtKB=K7E3F8 K7E3F8 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED RETROVIRAL ENVELOPE PROTEIN GP41-LIKE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000015236.4|UniProtKB=F6RCL7 F6RCL7 PTPRN PTHR46106:SF1 IA-2 PROTEIN TYROSINE PHOSPHATASE, ISOFORM C RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE-LIKE N peptide secretion#GO:0002790;signal release#GO:0023061;peptide hormone secretion#GO:0030072;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;protein localization to extracellular region#GO:0071692;cellular response to stimulus#GO:0051716;homeostatic process#GO:0042592;transport#GO:0006810;intracellular chemical homeostasis#GO:0055082;intracellular protein localization#GO:0008104;cellular homeostasis#GO:0019725;establishment of protein localization to extracellular region#GO:0035592;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;peptide transport#GO:0015833;nitrogen compound transport#GO:0071705;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;insulin secretion#GO:0030073;response to glucose#GO:0009749;response to oxygen-containing compound#GO:1901700;response to monosaccharide#GO:0034284;cellular response to chemical stimulus#GO:0070887;intracellular glucose homeostasis#GO:0001678;secretion by cell#GO:0032940;response to carbohydrate#GO:0009743;protein transport#GO:0015031;hormone secretion#GO:0046879;regulation of biological quality#GO:0065008;protein secretion#GO:0009306;cellular localization#GO:0051641;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;carbohydrate homeostasis#GO:0033500;response to hexose#GO:0009746;signaling#GO:0023052;export from cell#GO:0140352;response to stimulus#GO:0050896;chemical homeostasis#GO:0048878;hormone transport#GO:0009914;cellular response to glucose stimulus#GO:0071333;glucose homeostasis#GO:0042593;regulation of transport#GO:0051049;regulation of localization#GO:0032879;establishment of localization in cell#GO:0051649;cellular response to oxygen-containing compound#GO:1901701;establishment of protein localization#GO:0045184;cellular process#GO:0009987;response to chemical#GO:0042221 intracellular organelle#GO:0043229;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000000942.4|UniProtKB=F7F7V7 F7F7V7 PDGFD PTHR11633:SF4 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR D growth factor receptor binding#GO:0070851;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 positive regulation of MAPK cascade#GO:0043410;positive regulation of locomotion#GO:0040017;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;regulation of ERK1 and ERK2 cascade#GO:0070372;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Angiogenesis#P00005>PDGF#P00224 MONDO|Ensembl=ENSMODG00000046913.1|UniProtKB=A0A5F8GUE2 A0A5F8GUE2 PTHR26450:SF411 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51A7 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006776.4|UniProtKB=A0A5F8GTC8 A0A5F8GTC8 PTHR10689:SF9 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 PROSTAGLANDIN E SYNTHASE isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity#GO:0003824 monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;prostaglandin metabolic process#GO:0006693;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;icosanoid metabolic process#GO:0006690;biosynthetic process#GO:0009058;icosanoid biosynthetic process#GO:0046456;fatty acid biosynthetic process#GO:0006633;unsaturated fatty acid biosynthetic process#GO:0006636;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000006711.4|UniProtKB=H9H677 H9H677 GPR137 PTHR15146:SF5 INTEGRAL MEMBRANE PROTEIN GPR137 INTEGRAL MEMBRANE PROTEIN GPR137 regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;regulation of signaling#GO:0023051;regulation of bone resorption#GO:0045124;regulation of intracellular signal transduction#GO:1902531;regulation of myeloid cell differentiation#GO:0045637;positive regulation of signaling#GO:0023056;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;positive regulation of TORC1 signaling#GO:1904263;regulation of bone remodeling#GO:0046850;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of tissue remodeling#GO:0034103;positive regulation of TOR signaling#GO:0032008;regulation of hemopoiesis#GO:1903706;negative regulation of multicellular organismal process#GO:0051241;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764 MONDO|Ensembl=ENSMODG00000005050.4|UniProtKB=F7AT74 F7AT74 PTHR12300:SF133 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 6 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000014046.4|UniProtKB=F6UPL8 F6UPL8 PRODH2 PTHR13914:SF29 PROLINE OXIDASE HYDROXYPROLINE DEHYDROGENASE nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidase#PC00175 Huntington disease#P00029>Proline oxidase#G01529 MONDO|Ensembl=ENSMODG00000016024.3|UniProtKB=F7EFW0 F7EFW0 LOC100023632 PTHR41403:SF4 RCG43477-RELATED SIMILAR TO RIKEN CDNA 1700022C21 MONDO|Ensembl=ENSMODG00000002678.4|UniProtKB=A0A5F8H5X1 A0A5F8H5X1 TTC7B PTHR23083:SF365 TETRATRICOPEPTIDE REPEAT PROTEIN, TPR TETRATRICOPEPTIDE REPEAT PROTEIN 7B phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;protein localization to plasma membrane#GO:0072659;phosphorus metabolic process#GO:0006793;protein localization to membrane#GO:0072657;cellular localization#GO:0051641;organophosphate biosynthetic process#GO:0090407;localization#GO:0051179;localization within membrane#GO:0051668;phosphatidylinositol phosphate biosynthetic process#GO:0046854;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;protein localization to cell periphery#GO:1990778 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000028594.2|UniProtKB=K7E480 K7E480 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000010167.4|UniProtKB=F6TA59 F6TA59 TRPC4 PTHR10117:SF25 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 4 monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;binding#GO:0005488;alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;channel activity#GO:0015267;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803 monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;regulation of cytosolic calcium ion concentration#GO:0051480;homeostatic process#GO:0042592;metal ion transport#GO:0030001;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 MONDO|Ensembl=ENSMODG00000012443.4|UniProtKB=F6PI25 F6PI25 VPS13D PTHR16166:SF141 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13D molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013 cellular component organization#GO:0016043;catabolic process#GO:0009056;lipid localization#GO:0010876;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;autophagy#GO:0006914;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;macroautophagy#GO:0016236;lipid transport#GO:0006869;transport#GO:0006810;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234 mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle outer membrane#GO:0031968;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;outer membrane#GO:0019867;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle envelope#GO:0031967;mitochondrion#GO:0005739;vesicle#GO:0031982 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000003743.3|UniProtKB=F7ECU0 F7ECU0 DDX5 PTHR47958:SF90 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX5-RELATED nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000040370.1|UniProtKB=A0A5F8GNZ0 A0A5F8GNZ0 PMP2 PTHR11955:SF64 FATTY ACID BINDING PROTEIN MYELIN P2 PROTEIN binding#GO:0005488;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;ion binding#GO:0043167;organic acid binding#GO:0043177;fatty acid binding#GO:0005504;lipid binding#GO:0008289 macromolecule localization#GO:0033036;lipid transport#GO:0006869;lipid localization#GO:0010876;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;fatty acid transport#GO:0015908;localization#GO:0051179;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000011463.4|UniProtKB=F6W0U8 F6W0U8 PTHR10489:SF958 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR 5 LIKE-RELATED molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine receptor activity#GO:0004896 response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;defense response#GO:0006952;signal transduction#GO:0007165;immune response#GO:0006955;cellular process#GO:0009987;response to stress#GO:0006950;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;cell chemotaxis#GO:0060326;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;locomotion#GO:0040011;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000004545.4|UniProtKB=F6R5K0 F6R5K0 WDR86 PTHR44489:SF11 FAMILY NOT NAMED WD REPEAT DOMAIN 86 MONDO|Ensembl=ENSMODG00000036664.1|UniProtKB=A0A5F8HJY3 A0A5F8HJY3 GIMAP5 PTHR10903:SF69 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 5 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000023294.2|UniProtKB=F6VT36 F6VT36 PTHR42693:SF9 ARYLSULFATASE FAMILY MEMBER STERYL-SULFATASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000051411.1|UniProtKB=F6SWM8 F6SWM8 PTHR23262:SF7 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 2-2-RELATED structural protein#PC00211 MONDO|Ensembl=ENSMODG00000015954.4|UniProtKB=F7FRS8 F7FRS8 CCNYL1 PTHR14248:SF32 CYCLIN Y, ISOFORM A CYCLIN-Y-LIKE PROTEIN 1 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209 regulation of biological process#GO:0050789;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000001815.4|UniProtKB=F6T5P8 F6T5P8 ATOSA PTHR13199:SF13 GH03947P ATOS HOMOLOG PROTEIN A MONDO|Ensembl=ENSMODG00000037747.1|UniProtKB=A0A5F8HAD7 A0A5F8HAD7 TIMM21 PTHR13032:SF6 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21 protein localization to mitochondrion#GO:0070585;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966 MONDO|Ensembl=ENSMODG00000015490.4|UniProtKB=A0A5F8H7X2 A0A5F8H7X2 ING3 PTHR10333:SF114 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 3 chromatin-protein adaptor activity#GO:0140463;protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;nucleus#GO:0005634;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000010618.3|UniProtKB=F7G803 F7G803 LOC130456902 PTHR26451:SF876 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10K2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000016315.3|UniProtKB=F7A5K4 F7A5K4 CACNG3 PTHR12107:SF5 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-3 SUBUNIT molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel regulator activity#GO:0016247;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;transporter regulator activity#GO:0141108;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 regulation of biological quality#GO:0065008;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;localization#GO:0051179;cellular localization#GO:0051641;positive regulation of signaling#GO:0023056;localization within membrane#GO:0051668;regulation of signaling#GO:0023051;nervous system process#GO:0050877;positive regulation of synaptic transmission#GO:0050806;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;system process#GO:0003008;transmission of nerve impulse#GO:0019226;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702 voltage-gated ion channel#PC00241;ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000048715.1|UniProtKB=A0A5F8HKM4 A0A5F8HKM4 PTHR45869:SF21 C-REACTIVE PROTEIN-RELATED C-REACTIVE PROTEIN protein-lipid complex binding#GO:0071814;low-density lipoprotein particle binding#GO:0030169;binding#GO:0005488;complement binding#GO:0001848;lipoprotein particle binding#GO:0071813;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 immune system process#GO:0002376;inflammatory response#GO:0006954;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;acute inflammatory response#GO:0002526;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000025653.3|UniProtKB=F6XDY3 F6XDY3 LOC100031907 PTHR24300:SF177 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2J2 catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;binding#GO:0005488;tetrapyrrole binding#GO:0046906 metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000046426.1|UniProtKB=A0A5F8GLT8 A0A5F8GLT8 PON2 PTHR11799:SF17 PARAOXONASE SERUM PARAOXONASE_ARYLESTERASE 2 catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;response to toxic substance#GO:0009636;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;response to chemical#GO:0042221;response to stimulus#GO:0050896;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000013543.4|UniProtKB=F7CLU2 F7CLU2 SCN2B PTHR13869:SF3 MYELIN P0 RELATED SODIUM CHANNEL REGULATORY SUBUNIT BETA-2 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106 muscle contraction#GO:0006936;regulation of system process#GO:0044057;system process#GO:0003008;heart contraction#GO:0060047;cardiac muscle cell contraction#GO:0086003;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;actin filament-based movement#GO:0030048;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;cardiac muscle cell action potential involved in contraction#GO:0086002;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;heart process#GO:0003015;regulation of biological process#GO:0050789;action potential#GO:0001508;muscle system process#GO:0003012;regulation of heart contraction#GO:0008016;membrane depolarization#GO:0051899;striated muscle contraction#GO:0006941;actin-mediated cell contraction#GO:0070252 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;cation channel complex#GO:0034703;sodium channel complex#GO:0034706;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 myelin protein#PC00161 MONDO|Ensembl=ENSMODG00000038280.1|UniProtKB=A0A5F8H4X6 A0A5F8H4X6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000049794.1|UniProtKB=A0A5F8G1R8 A0A5F8G1R8 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000036410.1|UniProtKB=A0A5F8H8H7 A0A5F8H8H7 LOC100029341 PTHR26452:SF701 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 11L1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000014168.2|UniProtKB=F6U7A6 F6U7A6 PPP2CA PTHR45619:SF81 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT ALPHA ISOFORM hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protein phosphatase#PC00195 p53 pathway feedback loops 2#P04398>PP2A-C#P04659;Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;p53 pathway by glucose deprivation#P04397>PP2A-C#P04643;p53 pathway#P00059>PP2A#P04630;EGF receptor signaling pathway#P00018>PP2A#P00547 MONDO|Ensembl=ENSMODG00000043005.1|UniProtKB=F7BHZ8 F7BHZ8 PTHR11904:SF12 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 primary metabolic process#GO:0044238;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;pyridine-containing compound metabolic process#GO:0072524;purine nucleoside metabolic process#GO:0042278;organophosphate biosynthetic process#GO:0090407;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule catabolic process#GO:0034656;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;nucleoside catabolic process#GO:0009164;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine-containing compound catabolic process#GO:0072523;purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule metabolic process#GO:0055086 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 kinase#PC00137;nucleotide kinase#PC00172 Xanthine and guanine salvage pathway#P02788>Guanosine phosphorylase#P03250;Adenine and hypoxanthine salvage pathway#P02723>Deoxyinosine phosphorylase#P02812;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphorylase#P02805;Purine metabolism#P02769>Nucleoside Phosphorylase#P03115;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine phosphorylase#P02808;Adenine and hypoxanthine salvage pathway#P02723>Inosine phosphorylase#P02813;Xanthine and guanine salvage pathway#P02788>Deoxyguanosine phosphorylase#P03248 MONDO|Ensembl=ENSMODG00000007069.4|UniProtKB=A0A5F8GU07 A0A5F8GU07 PARD3 PTHR16484:SF10 PARTITIONING DEFECTIVE 3 RELATED PARTITIONING DEFECTIVE 3 HOMOLOG anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091;binding#GO:0005488;ion binding#GO:0043167 cytoskeleton organization#GO:0007010;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;establishment of cell polarity#GO:0030010;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell adhesion#GO:0007155;establishment or maintenance of bipolar cell polarity#GO:0061245 cell periphery#GO:0071944;cell cortex#GO:0005938;membrane#GO:0016020;cell-cell junction#GO:0005911;apical plasma membrane#GO:0016324;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;apical part of cell#GO:0045177;apical junction complex#GO:0043296;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;adherens junction#GO:0005912;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000005385.4|UniProtKB=F7GGG1 F7GGG1 HAO2 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058 microbody#GO:0042579;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000016553.3|UniProtKB=F7DNS0 F7DNS0 PTHR11005:SF26 LYSOSOMAL ACID LIPASE-RELATED LYSOSOMAL ACID LIPASE_CHOLESTERYL ESTER HYDROLASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 hydrolase#PC00121;lipase#PC00143 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol esterase#P02830 MONDO|Ensembl=ENSMODG00000013545.3|UniProtKB=F7C3L8 F7C3L8 RPS16 PTHR21569:SF16 RIBOSOMAL PROTEIN S9 SMALL RIBOSOMAL SUBUNIT PROTEIN US9 structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000015755.4|UniProtKB=F6ZSZ9 F6ZSZ9 ERBB4 PTHR24416:SF90 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;growth factor receptor binding#GO:0070851;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;signaling receptor binding#GO:0005102;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;nervous system development#GO:0007399;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;multicellular organismal process#GO:0032501;epidermal growth factor receptor signaling pathway#GO:0007173;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;ERBB signaling pathway#GO:0038127;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of epithelial cell proliferation#GO:0050679;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>EGFR#P00466;Alzheimer disease-presenilin pathway#P00004>Erb-B4 transmembrane fragment#P00113;Alzheimer disease-presenilin pathway#P00004>Erb-B4 C-terminal fragment#P00163;Alzheimer disease-presenilin pathway#P00004>Erb-B4#P00128;Alzheimer disease-presenilin pathway#P00004>Erb-B4 N-terminal fragment#P00148;EGF receptor signaling pathway#P00018>EGFR#P00542 MONDO|Ensembl=ENSMODG00000013810.4|UniProtKB=F6SXE3 F6SXE3 WNT3A PTHR12027:SF88 WNT RELATED PROTEIN WNT-3A signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125 regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;system development#GO:0048731;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 MONDO|Ensembl=ENSMODG00000004746.4|UniProtKB=F6XJ69 F6XJ69 SYBU PTHR16208:SF4 MICROTUBULE-ASSOCIATED PROTEIN/SYNTAPHILIN SYNTABULIN establishment of localization in cell#GO:0051649;cellular process#GO:0009987;axo-dendritic transport#GO:0008088;nervous system development#GO:0007399;organelle transport along microtubule#GO:0072384;developmental maturation#GO:0021700;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;developmental process#GO:0032502;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;mitochondrion localization#GO:0051646;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;cell junction organization#GO:0034330;establishment of organelle localization#GO:0051656;microtubule-based transport#GO:0099111;synapse organization#GO:0050808;axonal transport#GO:0098930;animal gross anatomical part developmental process#GO:0160108;organelle localization#GO:0051640;system development#GO:0048731;localization#GO:0051179;cellular localization#GO:0051641;anatomical structure development#GO:0048856 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 SNARE protein#PC00034 MONDO|Ensembl=ENSMODG00000009958.4|UniProtKB=A0A5F8HEW3 A0A5F8HEW3 ATP1A2 PTHR43294:SF6 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-2 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;export from cell#GO:0140352;homeostatic process#GO:0042592;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801 ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;plasma membrane#GO:0005886;cell projection#GO:0042995;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000000218.4|UniProtKB=F6SZJ5 F6SZJ5 VSTM2L PTHR12207:SF31 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000011217.4|UniProtKB=F6S7Y6 F6S7Y6 MASP2 PTHR24255:SF10 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED MANNAN-BINDING LECTIN SERINE PROTEASE 2 serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 positive regulation of immune response#GO:0050778;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;humoral immune response#GO:0006959;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;immune response#GO:0006955;complement activation#GO:0006956;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;defense response to other organism#GO:0098542;regulation of immune response#GO:0050776;immune system process#GO:0002376;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000015793.4|UniProtKB=A0A5F8H2V7 A0A5F8H2V7 CPS1 PTHR11405:SF58 CARBAMOYLTRANSFERASE FAMILY MEMBER CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;ligase#PC00142 De novo pyrimidine ribonucleotides biosythesis#P02740>Carbamoyl phosphate synthetase#P02925;Arginine biosynthesis#P02728>Carbamoyl phosphate synthase#P02845 MONDO|Ensembl=ENSMODG00000025761.3|UniProtKB=F7G3J8 F7G3J8 BCAS4 PTHR16230:SF5 CAPPUCCINO BREAST CARCINOMA-AMPLIFIED SEQUENCE 4 melanosome organization#GO:0032438;pigmentation#GO:0043473;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular pigmentation#GO:0033059 protein-containing complex#GO:0032991;BLOC-1 complex#GO:0031083;intracellular protein-containing complex#GO:0140535 MONDO|Ensembl=ENSMODG00000004020.4|UniProtKB=F7D6H6 F7D6H6 AMBP PTHR46676:SF1 PROTEIN AMBP PROTEIN AMBP endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000006586.3|UniProtKB=F7B7D5 F7B7D5 MED19 PTHR22536:SF1 LUNG CANCER METASTASIS-RELATED LCMR1 PROTEIN MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 19 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000007167.4|UniProtKB=A0A5F8HGH7 A0A5F8HGH7 FAM118A PTHR28623:SF2 PROTEIN FAM118B PROTEIN FAM118A catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 immune system process#GO:0002376;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542 MONDO|Ensembl=ENSMODG00000009209.4|UniProtKB=F6YZ91 F6YZ91 LOC100019315 PTHR45696:SF10 60S ACIDIC RIBOSOMAL PROTEIN P1 LARGE RIBOSOMAL SUBUNIT PROTEIN P1 structural molecule activity#GO:0005198;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;structural constituent of ribosome#GO:0003735;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209;binding#GO:0005488 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000005613.4|UniProtKB=F7CZF3 F7CZF3 FBXO38 PTHR14753:SF3 F-BOX ONLY PROTEIN 38 F-BOX ONLY PROTEIN 38 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;regulation of immune response#GO:0050776;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;regulation of leukocyte mediated immunity#GO:0002703;regulation of immune system process#GO:0002682;catabolic process#GO:0009056;regulation of response to biotic stimulus#GO:0002831;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;positive regulation of leukocyte mediated immunity#GO:0002705;protein K48-linked ubiquitination#GO:0070936;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of response to stimulus#GO:0048584;post-translational protein modification#GO:0043687;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;protein modification by small protein conjugation or removal#GO:0070647;regulation of lymphocyte mediated immunity#GO:0002706;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;positive regulation of adaptive immune response#GO:0002821;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000014923.3|UniProtKB=F7FVR4 F7FVR4 PSMC3IP PTHR15938:SF0 TBP-1 INTERACTING PROTEIN HOMOLOGOUS-PAIRING PROTEIN 2 HOMOLOG enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;double-stranded DNA binding#GO:0003690 nucleobase-containing compound metabolic process#GO:0006139;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;reproductive process#GO:0022414;homologous recombination#GO:0035825;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;reciprocal homologous recombination#GO:0140527;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;homologous chromosome pairing at meiosis#GO:0007129;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;DNA metabolic process#GO:0006259;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;chromosome segregation#GO:0007059;DNA recombination#GO:0006310;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle process#GO:0022402;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;condensed chromosome#GO:0000793;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009 General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;General transcription regulation#P00023>TBP#P00670;General transcription by RNA polymerase I#P00022>SL1 complex#P00653 MONDO|Ensembl=ENSMODG00000042530.1|UniProtKB=A0A5F8GEI0 A0A5F8GEI0 TGIF2 PTHR11850:SF413 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS TGFB INDUCED FACTOR HOMEOBOX 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000006079.4|UniProtKB=F7FER2 F7FER2 OLFML1 PTHR23192:SF13 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 1 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000015622.4|UniProtKB=F6YFN8 F6YFN8 TMEM150A PTHR21324:SF6 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED TRANSMEMBRANE PROTEIN 150A localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;protein localization to plasma membrane#GO:0072659;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018524.3|UniProtKB=A0A5F8GKS1 A0A5F8GKS1 MSL2 PTHR16048:SF3 MSL2-RELATED E3 UBIQUITIN-PROTEIN LIGASE MSL2 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000017702.4|UniProtKB=F7FUS9 F7FUS9 TOP3B PTHR11390:SF20 PROKARYOTIC DNA TOPOISOMERASE DNA TOPOISOMERASE 3-BETA-1 nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853 DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000015640.4|UniProtKB=F7F185 F7F185 ISOC1 PTHR14119:SF17 HYDROLASE ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000029643.2|UniProtKB=K7E1X0 K7E1X0 LOC103102562 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008865.4|UniProtKB=A0A5F8GZL2 A0A5F8GZL2 TIAL1 PTHR10352:SF11 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G NUCLEOLYSIN TIAR regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000018423.4|UniProtKB=A0A5F8GR19 A0A5F8GR19 TNK2 PTHR24418:SF384 TYROSINE-PROTEIN KINASE ACTIVATED CDC42 KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 MONDO|Ensembl=ENSMODG00000037119.1|UniProtKB=A0A5F8HDL2 A0A5F8HDL2 ST6GALNAC6 PTHR45906:SF6 ALPHA-N-ACETYL-NEURAMINYL-2,3-BETA-GALACTOSYL-1, 3-N-ACETYL-GALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE-LIKE ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 6 catalytic activity#GO:0003824;transferase activity#GO:0016740;sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757 metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;carbohydrate derivative biosynthetic process#GO:1901137;oligosaccharide metabolic process#GO:0009311;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;glycosphingolipid biosynthetic process#GO:0006688;glycolipid biosynthetic process#GO:0009247;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;carbohydrate metabolic process#GO:0005975 MONDO|Ensembl=ENSMODG00000043266.1|UniProtKB=A0A5F8GQX7 A0A5F8GQX7 POU6F2 PTHR11636:SF68 POU DOMAIN POU DOMAIN, CLASS 6, TRANSCRIPTION FACTOR 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000044188.1|UniProtKB=A0A5F8H3J0 A0A5F8H3J0 PTHR23267:SF313 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 5-2 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000007853.4|UniProtKB=F7ET62 F7ET62 PPP1R42 PTHR46652:SF7 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 42 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000038165.1|UniProtKB=F7FBW8 F7FBW8 LOC100019050 PTHR26450:SF7 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021493.3|UniProtKB=F7G2T2 F7G2T2 PTHR15107:SF4 RETINOBLASTOMA BINDING PROTEIN 8 DNA ENDONUCLEASE RBBP8 nucleic acid binding#GO:0003676;binding#GO:0005488;damaged DNA binding#GO:0003684;DNA binding#GO:0003677 double-strand break repair via single-strand annealing#GO:0045002;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000006231.4|UniProtKB=F6VC49 F6VC49 PTHR13723:SF159 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE PLAC DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000048752.1|UniProtKB=A0A5F8H619 A0A5F8H619 GDF9 PTHR11848:SF19 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 9 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000001531.4|UniProtKB=F7EM76 F7EM76 PTHR15036:SF51 PIKACHURIN-LIKE PROTEIN NEUREXIN-1 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor activity#GO:0038023;protein binding#GO:0005515;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;macromolecule localization#GO:0033036;system process#GO:0003008;intracellular protein localization#GO:0008104;developmental process#GO:0032502;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;postsynapse organization#GO:0099173;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;cell communication#GO:0007154;localization#GO:0051179;system development#GO:0048731;postsynaptic specialization organization#GO:0099084;cognition#GO:0050890;organelle assembly#GO:0070925;protein localization to cell junction#GO:1902414;synapse organization#GO:0050808;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;postsynaptic density assembly#GO:0097107;signal transduction#GO:0007165;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;protein localization to synapse#GO:0035418;synapse assembly#GO:0007416;response to stimulus#GO:0050896;signaling#GO:0023052;excitatory synapse assembly#GO:1904861;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789;animal gross anatomical part developmental process#GO:0160108;nervous system process#GO:0050877;postsynaptic density organization#GO:0097106 synapse#GO:0045202;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;presynaptic active zone membrane#GO:0048787;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;presynaptic active zone#GO:0048786;cell junction#GO:0030054;synaptic membrane#GO:0097060 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000006355.4|UniProtKB=A0A5F8GLA3 A0A5F8GLA3 PDE10A PTHR11347:SF111 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP AND CAMP-INHIBITED CGMP 3',5'-CYCLIC PHOSPHODIESTERASE 10A hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 phosphodiesterase#PC00185;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000015646.4|UniProtKB=F7F0V5 F7F0V5 PPM1G PTHR13832:SF872 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1G phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000015598.4|UniProtKB=F6ZTR8 F6ZTR8 STX2 PTHR19957:SF36 SYNTAXIN SYNTAXIN-2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;secretion by cell#GO:0032940;vesicle fusion#GO:0006906;export from cell#GO:0140352;cellular component organization#GO:0016043;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;exocytosis#GO:0006887;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;macromolecule localization#GO:0033036;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 intracellular anatomical structure#GO:0005622;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;SNARE complex#GO:0031201;cytoplasm#GO:0005737;plasma membrane#GO:0005886 SNARE protein#PC00034 Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 MONDO|Ensembl=ENSMODG00000006430.4|UniProtKB=A0A5F8HC22 A0A5F8HC22 RABGEF1 PTHR23101:SF122 RAB GDP/GTP EXCHANGE FACTOR RAB5 GDP_GTP EXCHANGE FACTOR nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytosol#GO:0005829 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000017839.3|UniProtKB=F6Z8F3 F6Z8F3 TGM5 PTHR11590:SF38 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 5 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 transferase#PC00220 MONDO|Ensembl=ENSMODG00000009236.4|UniProtKB=F7EDS3 F7EDS3 GAB3 PTHR45960:SF3 GRB2-ASSOCIATED-BINDING PROTEIN GRB2-ASSOCIATED-BINDING PROTEIN 3 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Gab#P00563 MONDO|Ensembl=ENSMODG00000017390.4|UniProtKB=F6SL53 F6SL53 S100A14 PTHR11639:SF4 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A14 metal ion binding#GO:0046872;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;cation binding#GO:0043169;small molecule binding#GO:0036094;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;ion binding#GO:0043167;calcium ion binding#GO:0005509;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway#GO:0007166;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;response to lipopolysaccharide#GO:0032496;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;regulation of response to external stimulus#GO:0032101;response to lipid#GO:0033993;response to chemical#GO:0042221;immune system process#GO:0002376;response to oxygen-containing compound#GO:1901700;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;immune response-regulating signaling pathway#GO:0002764;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of locomotion#GO:0040017;activation of innate immune response#GO:0002218;positive regulation of cell migration#GO:0030335;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;toll-like receptor 4 signaling pathway#GO:0034142;response to bacterium#GO:0009617;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of granulocyte chemotaxis#GO:0071622;positive regulation of chemotaxis#GO:0050921;regulation of cell motility#GO:2000145;cell communication#GO:0007154;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of leukocyte migration#GO:0002685;regulation of response to biotic stimulus#GO:0002831;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to external biotic stimulus#GO:0043207 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;perinuclear region of cytoplasm#GO:0048471;extracellular region#GO:0005576 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000012326.3|UniProtKB=F7E2R5 F7E2R5 PDCD5 PTHR10840:SF0 PROGRAMMED CELL DEATH PROTEIN 5 PROGRAMMED CELL DEATH PROTEIN 5 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000017155.4|UniProtKB=F6QE12 F6QE12 KCNN3 PTHR10153:SF40 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 3 monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;calcium-activated potassium channel activity#GO:0015269;ligand-gated channel activity#GO:0022834;monoatomic ion-gated channel activity#GO:0022839;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;calmodulin binding#GO:0005516;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;gated channel activity#GO:0022836;binding#GO:0005488 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;potassium ion transport#GO:0006813;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cell body#GO:0044297 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000020124.4|UniProtKB=A0A5F8GTI3 A0A5F8GTI3 SLF1 PTHR46677:SF1 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 1 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 1 intracellular protein localization#GO:0008104;localization#GO:0051179;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;protein localization to organelle#GO:0033365;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;macromolecule localization#GO:0033036 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;site of double-strand break#GO:0035861;chromosome#GO:0005694;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000051026.1|UniProtKB=A0A5F8H6Y2 A0A5F8H6Y2 monDomV1R1261 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000042194.1|UniProtKB=A0A5F8G2E0 A0A5F8G2E0 PTHR22932:SF4 TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE PROTEIN PTGES3L-RELATED protein binding#GO:0005515;heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein folding#GO:0006457;chaperone-mediated protein complex assembly#GO:0051131;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000009786.4|UniProtKB=F6SZR6 F6SZR6 ECI2 PTHR43684:SF17 FAMILY NOT NAMED ENOYL-COA DELTA ISOMERASE 2 catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329 intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777 MONDO|Ensembl=ENSMODG00000018072.3|UniProtKB=F7CL62 F7CL62 PTHR23161:SF2 PROTEIN CIP2A PROTEIN CIP2A molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;organelle organization#GO:0006996;cellular component organization#GO:0016043;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000028612.2|UniProtKB=K7E3X4 K7E3X4 PRR11 PTHR23330:SF9 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED PROLINE-RICH PROTEIN 11 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000011014.4|UniProtKB=F7FVC5 F7FVC5 RECQL4 PTHR13710:SF167 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q4 ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678 DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;telomere maintenance#GO:0000723;double-strand break repair#GO:0006302;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;telomere organization#GO:0032200;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896 nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009;DNA helicase#PC00011 MONDO|Ensembl=ENSMODG00000010561.4|UniProtKB=F6YR67 F6YR67 KCNJ13 PTHR11767:SF3 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 13 potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000012505.3|UniProtKB=A0A5F8GZH1 A0A5F8GZH1 KPNB1 PTHR10527:SF1 IMPORTIN BETA IMPORTIN SUBUNIT BETA-1 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 nucleocytoplasmic transport#GO:0006913;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000040330.1|UniProtKB=A0A5F8GHS9 A0A5F8GHS9 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000038881.1|UniProtKB=A0A5F8HDC7 A0A5F8HDC7 PTHR15825:SF5 UBIQUITIN-FOLD MODIFIER 1 UBIQUITIN-FOLD MODIFIER 1 macroautophagy#GO:0016236;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;autophagy#GO:0006914;response to stress#GO:0006950;reticulophagy#GO:0061709;process utilizing autophagic mechanism#GO:0061919;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000027380.2|UniProtKB=A0A5F8H6P1 A0A5F8H6P1 PTHR16675:SF289 MHC CLASS I-RELATED ZINC-ALPHA-2-GLYCOPROTEIN positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of immune system process#GO:0002684;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000014965.3|UniProtKB=F7DQB2 F7DQB2 PTHR23253:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 1 RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;translation factor activity#GO:0180051 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000015608.4|UniProtKB=F6Z550 F6Z550 GCKR PTHR10088:SF4 GLUCOKINASE REGULATORY PROTEIN GLUCOKINASE REGULATORY PROTEIN molecular sensor activity#GO:0140299;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857;carbohydrate derivative binding#GO:0097367;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167 chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;glucose homeostasis#GO:0042593;intracellular glucose homeostasis#GO:0001678;intracellular protein localization#GO:0008104;localization#GO:0051179;carbohydrate homeostasis#GO:0033500;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;homeostatic process#GO:0042592;protein localization to organelle#GO:0033365 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000010228.4|UniProtKB=F6WLQ1 F6WLQ1 EXD2 PTHR13620:SF133 3-5 EXONUCLEASE EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2 catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;DNA exonuclease activity#GO:0004529;hydrolase activity#GO:0016787;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175 cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;recombinational repair#GO:0000725;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;DNA recombination#GO:0006310;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000018481.4|UniProtKB=F7DXB7 F7DXB7 AKR1E2 PTHR11732:SF391 ALDO/KETO REDUCTASE 1,5-ANHYDRO-D-FRUCTOSE REDUCTASE catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 reductase#PC00198;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000017214.4|UniProtKB=F6WXU2 F6WXU2 YBX1 PTHR11544:SF143 COLD SHOCK DOMAIN CONTAINING PROTEINS Y-BOX-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488 biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000008040.4|UniProtKB=A0A5F8GD44 A0A5F8GD44 TRIM55 PTHR25462:SF293 BONUS, ISOFORM C-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM63A acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000006633.3|UniProtKB=F7G4I0 F7G4I0 HMOX2 PTHR10720:SF2 HEME OXYGENASE HEME OXYGENASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;tetrapyrrole binding#GO:0046906;binding#GO:0005488 response to oxidative stress#GO:0006979;porphyrin-containing compound metabolic process#GO:0006778;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;heme metabolic process#GO:0042168;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular process#GO:0009987;response to stress#GO:0006950;pigment metabolic process#GO:0042440 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000023595.3|UniProtKB=A0A5F8GII4 A0A5F8GII4 LOC130458153 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000048736.1|UniProtKB=K7DZE6 K7DZE6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000049680.1|UniProtKB=A0A5F8G3V2 A0A5F8G3V2 PTHR34930:SF5 GEO05313P1 JUPITER MICROTUBULE ASSOCIATED HOMOLOG 2 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000023787.2|UniProtKB=F6WPR1 F6WPR1 TSSK6 PTHR24343:SF166 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 6 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell differentiation#GO:0030154;gamete generation#GO:0007276;reproductive process#GO:0022414;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;spermatid differentiation#GO:0048515;sexual reproduction#GO:0019953;spermatid development#GO:0007286;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000002216.4|UniProtKB=F7CW60 F7CW60 ARHGAP22 PTHR15228:SF22 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 22 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of biological quality#GO:0065008;negative regulation of cell communication#GO:0010648;regulation of synapse structure or activity#GO:0050803;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of synapse organization#GO:0050807;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000037525.1|UniProtKB=A0A5F8H080 A0A5F8H080 ZFP36 PTHR12547:SF58 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36 RNA binding#GO:0003723;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA 3'-UTR binding#GO:0003730;translation regulator activity#GO:0045182;molecular adaptor activity#GO:0060090;protein-RNA adaptor activity#GO:0140517 positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000016813.4|UniProtKB=F7FV80 F7FV80 MSLN PTHR23412:SF6 STEREOCILIN RELATED MESOTHELIN cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cellular process#GO:0009987 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000028191.2|UniProtKB=K7E3Z5 K7E3Z5 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000029411.2|UniProtKB=K7DYS6 K7DYS6 SPMIP1 PTHR35826:SF2 PROTEIN ATP6V1FNB-LIKE PROTEIN SPMIP1 MONDO|Ensembl=ENSMODG00000011982.4|UniProtKB=F7B9K3 F7B9K3 ISL2 PTHR24204:SF2 INSULIN GENE ENHANCER PROTEIN INSULIN GENE ENHANCER PROTEIN ISL-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of metabolic process#GO:0019222;neuron fate commitment#GO:0048663;regulation of primary metabolic process#GO:0080090;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cell fate specification#GO:0001708;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;cell fate commitment#GO:0045165;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000017594.2|UniProtKB=H9H737 H9H737 RPA3 PTHR15114:SF1 REPLICATION PROTEIN A3 REPLICATION PROTEIN A 14 KDA SUBUNIT binding#GO:0005488;nucleic acid binding#GO:0003676;damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;mismatch repair#GO:0006298;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;replisome#GO:0030894;replication fork#GO:0005657;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;site of double-strand break#GO:0035861;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 Cell cycle#P00013>Pre-replication Complex#P00478 MONDO|Ensembl=ENSMODG00000018749.5|UniProtKB=F7EF39 F7EF39 ITGA10 PTHR23220:SF26 INTEGRIN ALPHA INTEGRIN ALPHA-10 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell surface receptor signaling pathway#GO:0007166;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 MONDO|Ensembl=ENSMODG00000009263.4|UniProtKB=A0A5F8H138 A0A5F8H138 PTHR44427:SF1 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CELL ADHESION MOLECULE CEACAM1 protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000019809.4|UniProtKB=F6SU86 F6SU86 SLC2A8 PTHR48021:SF18 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 8 carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;carbohydrate transport#GO:0008643;transport#GO:0006810;carbohydrate transmembrane transport#GO:0034219;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000003550.4|UniProtKB=F7GBI8 F7GBI8 TMEM59L PTHR28652:SF1 TRANSMEMBRANE PROTEIN 59-LIKE PROTEIN TRANSMEMBRANE PROTEIN 59-LIKE MONDO|Ensembl=ENSMODG00000047585.1|UniProtKB=A0A5F8HGX8 A0A5F8HGX8 GEMIN8 PTHR16238:SF7 GEM-ASSOCIATED PROTEIN 8 GEM-ASSOCIATED PROTEIN 8 RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 SMN complex#GO:0032797;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;Sm-like protein family complex#GO:0120114 MONDO|Ensembl=ENSMODG00000048938.1|UniProtKB=A0A5F8GKF2 A0A5F8GKF2 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000015997.4|UniProtKB=F7EZ09 F7EZ09 FASTKD2 PTHR21228:SF1 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 2, MITOCHONDRIAL binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;cellular process#GO:0009987;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 membraneless organelle#GO:0043228;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000017990.4|UniProtKB=F7B8G7 F7B8G7 SESN1 PTHR12474:SF3 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN-1 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;cation binding#GO:0043169;organic acid binding#GO:0043177;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;amino acid binding#GO:0016597 regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;response to nitrogen compound#GO:1901698;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;positive regulation of macroautophagy#GO:0016239;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;negative regulation of signal transduction#GO:0009968;response to chemical#GO:0042221;cellular response to amino acid starvation#GO:0034198;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;regulation of macroautophagy#GO:0016241;negative regulation of TORC1 signaling#GO:1904262 peroxidase#PC00180;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000017290.3|UniProtKB=F6SM16 F6SM16 ABRACL PTHR46334:SF1 COSTARS FAMILY PROTEIN ABRACL COSTARS FAMILY PROTEIN ABRACL regulation of biological process#GO:0050789;regulation of actin filament-based process#GO:0032970;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 MONDO|Ensembl=ENSMODG00000043097.1|UniProtKB=K7E0H6 K7E0H6 PTHR46890:SF56 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED OS06G0484800 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000019887.4|UniProtKB=F7CEN4 F7CEN4 PHF21A PTHR24102:SF6 PHD FINGER PROTEIN PHD FINGER PROTEIN 21A chromatin binding#GO:0003682;binding#GO:0005488 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000037264.1|UniProtKB=A0A5F8GJV6 A0A5F8GJV6 EMILIN3 PTHR15427:SF2 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMILIN-3 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;supramolecular fiber#GO:0099512;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;protein complex involved in cell adhesion#GO:0098636;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;interstitial matrix#GO:0005614 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000037337.1|UniProtKB=F6TC32 F6TC32 LOC100025780 PTHR12960:SF0 GLE-1-RELATED MRNA EXPORT FACTOR GLE1 translation initiation factor binding#GO:0031369;alcohol binding#GO:0043178;phospholipid binding#GO:0005543;protein binding#GO:0005515;lipid binding#GO:0008289;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;biosynthetic process#GO:0009058;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 translation factor#PC00223 MONDO|Ensembl=ENSMODG00000015838.4|UniProtKB=A0A5F8HD99 A0A5F8HD99 MBNL1 PTHR12675:SF7 MUSCLEBLIND-LIKE PROTEIN MUSCLEBLIND-LIKE PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000003103.4|UniProtKB=F6PII5 F6PII5 VASH2 PTHR15750:SF4 VASOHIBIN-1-LIKE ISOFORM X2 TUBULINYL-TYR CARBOXYPEPTIDASE 2 regulation of angiogenesis#GO:0045765;regulation of anatomical structure morphogenesis#GO:0022603;regulation of vasculature development#GO:1901342;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000000617.2|UniProtKB=F6TAY5 F6TAY5 LOC103102954 PTHR10157:SF31 DOPAMINE BETA HYDROXYLASE RELATED DBH-LIKE MONOOXYGENASE PROTEIN 2-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;secretory granule membrane#GO:0030667;intracellular vesicle#GO:0097708;vesicle#GO:0031982;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020 hydroxylase#PC00122 MONDO|Ensembl=ENSMODG00000007011.4|UniProtKB=F6XTW9 F6XTW9 RBSN PTHR13510:SF44 FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED RABENOSYN-5 MONDO|Ensembl=ENSMODG00000002739.4|UniProtKB=F6Z703 F6Z703 NOX4 PTHR11972:SF206 NADPH OXIDASE NADPH OXIDASE 4 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664 metabolic process#GO:0008152;response to stress#GO:0006950;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987;response to stimulus#GO:0050896;superoxide metabolic process#GO:0006801;defense response#GO:0006952 membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;catalytic complex#GO:1902494 oxidase#PC00175;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000016608.3|UniProtKB=F6ZCT5 F6ZCT5 PRELID3B PTHR11158:SF22 MSF1/PX19 RELATED PRELI DOMAIN CONTAINING PROTEIN 3B lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 phospholipid transport#GO:0015914;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;lipid localization#GO:0010876 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000013648.4|UniProtKB=F6UDZ5 F6UDZ5 ATG12 PTHR13385:SF0 AUTOPHAGY PROTEIN 12 UBIQUITIN-LIKE PROTEIN ATG12 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;polysaccharide catabolic process#GO:0000272;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;carbohydrate catabolic process#GO:0016052;cellular component assembly#GO:0022607;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;piecemeal microautophagy of the nucleus#GO:0034727;carbohydrate metabolic process#GO:0005975;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;vacuole organization#GO:0007033;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;macroautophagy#GO:0016236;glycogen catabolic process#GO:0005980;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;generation of precursor metabolites and energy#GO:0006091;autophagosome maturation#GO:0097352;autophagy of mitochondrion#GO:0000422 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;phagophore assembly site#GO:0000407;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000047216.1|UniProtKB=F6Y8H7 F6Y8H7 PTHR24381:SF479 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 432 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000019641.3|UniProtKB=F6URG6 F6URG6 C5 PTHR11412:SF83 MACROGLOBULIN / COMPLEMENT COMPLEMENT C5 chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379 regulation of immune response#GO:0050776;chemotaxis#GO:0006935;regulation of immune system process#GO:0002682;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;adaptive immune response#GO:0002250;biological regulation#GO:0065007;complement activation#GO:0006956;immune response#GO:0006955;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;humoral immune response#GO:0006959;immune effector process#GO:0002252;defense response to other organism#GO:0098542;taxis#GO:0042330;response to chemical#GO:0042221;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;activation of immune response#GO:0002253;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000001844.3|UniProtKB=F6SPF3 F6SPF3 MMP24 PTHR10201:SF138 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-24 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;metabolic process#GO:0008152;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130;Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141 MONDO|Ensembl=ENSMODG00000043293.1|UniProtKB=A0A5F8GBT0 A0A5F8GBT0 PTHR11716:SF9 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2, MEMBRANE ASSOCIATED hydrolase activity, acting on ester bonds#GO:0016788;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;A2-type glycerophospholipase activity#GO:0004623;calcium ion binding#GO:0005509;binding#GO:0005488;lipid binding#GO:0008289;metal ion binding#GO:0046872 lipid metabolic process#GO:0006629;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;negative regulation of cell activation#GO:0050866;organophosphate metabolic process#GO:0019637;negative regulation of cell population proliferation#GO:0008285;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of cell adhesion#GO:0007162;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;negative regulation of multicellular organismal process#GO:0051241;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;negative regulation of leukocyte cell-cell adhesion#GO:1903038;phosphatidylglycerol metabolic process#GO:0046471;regulation of T cell proliferation#GO:0042129;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;metabolic process#GO:0008152;negative regulation of T cell proliferation#GO:0042130;regulation of leukocyte proliferation#GO:0070663;cellular process#GO:0009987;regulation of mononuclear cell proliferation#GO:0032944;regulation of multicellular organismal process#GO:0051239;negative regulation of lymphocyte activation#GO:0051250;negative regulation of leukocyte activation#GO:0002695;glycerophospholipid metabolic process#GO:0006650;negative regulation of cell-cell adhesion#GO:0022408;phosphatidylcholine metabolic process#GO:0046470;regulation of T cell activation#GO:0050863;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;phosphorus metabolic process#GO:0006793;regulation of lymphocyte activation#GO:0051249;glycerolipid metabolic process#GO:0046486 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000014671.3|UniProtKB=F7E7Z8 F7E7Z8 LDHD PTHR11748:SF111 D-LACTATE DEHYDROGENASE D-LACTATE DEHYDROGENASE, MITOCHONDRIAL nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;small molecule binding#GO:0036094;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid catabolic process#GO:0072329;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000012348.5|UniProtKB=A0A5F8G5F3 A0A5F8G5F3 CAMKV PTHR24347:SF18 SERINE/THREONINE-PROTEIN KINASE CAM KINASE-LIKE VESICLE-ASSOCIATED PROTEIN protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;calmodulin binding#GO:0005516;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000002821.3|UniProtKB=F7EJ46 F7EJ46 PTAR1 PTHR11129:SF3 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT PROTEIN PRENYLTRANSFERASE ALPHA SUBUNIT REPEAT-CONTAINING PROTEIN 1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000015160.3|UniProtKB=F6S4W7 F6S4W7 TMEM106A PTHR28556:SF3 TRANSMEMBRANE PROTEIN 106B TRANSMEMBRANE PROTEIN 106A cell activation#GO:0001775;cellular process#GO:0009987;immune system process#GO:0002376;leukocyte activation#GO:0045321;multicellular organismal process#GO:0032501;macrophage activation#GO:0042116;myeloid leukocyte activation#GO:0002274 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852 MONDO|Ensembl=ENSMODG00000036915.1|UniProtKB=A0A5F8H7Z0 A0A5F8H7Z0 PTHR19446:SF479 REVERSE TRANSCRIPTASES RNA-DIRECTED DNA POLYMERASE viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000011554.4|UniProtKB=F6QWC2 F6QWC2 MRS2 PTHR13890:SF0 RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;magnesium ion transmembrane transporter activity#GO:0015095;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;magnesium ion transport#GO:0015693;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000019460.5|UniProtKB=F6RWN1 F6RWN1 KIF3B PTHR24115:SF744 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3B hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;microtubule-based process#GO:0007017 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000006882.4|UniProtKB=F6PWB7 F6PWB7 SDC2 PTHR10915:SF6 SYNDECAN SYNDECAN-2 dendrite morphogenesis#GO:0048813;regulation of cellular process#GO:0050794;regulation of cell junction assembly#GO:1901888;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of synapse organization#GO:0050807;dendrite development#GO:0016358;neuron development#GO:0048666;regulation of biological quality#GO:0065008;neuron projection development#GO:0031175;cellular process#GO:0009987;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000046897.1|UniProtKB=A0A5F8GEM5 A0A5F8GEM5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000049054.1|UniProtKB=F6UEM6 F6UEM6 PTHR48001:SF128 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000044325.1|UniProtKB=A0A5F8H7S5 A0A5F8H7S5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000050525.1|UniProtKB=A0A5F8GFI7 A0A5F8GFI7 FAM180A PTHR34034:SF2 PROTEIN FAM180A-RELATED PROTEIN FAM180A MONDO|Ensembl=ENSMODG00000027514.2|UniProtKB=K7E5C5 K7E5C5 KIAA1586 PTHR46880:SF14 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE KIAA1586 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein sumoylation#GO:0016925;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687 MONDO|Ensembl=ENSMODG00000012878.3|UniProtKB=F6ZP21 F6ZP21 OR4D5 PTHR48002:SF49 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D5 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048266.1|UniProtKB=F6SJ94 F6SJ94 PTHR26453:SF303 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2Y1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019582.3|UniProtKB=F6QMA5 F6QMA5 DEPDC1B PTHR16206:SF11 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 1B positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signal transduction#GO:0009967 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000047827.1|UniProtKB=A0A5F8GH92 A0A5F8GH92 PTHR47166:SF1 ZINC FINGER PROTEIN 831 ZINC FINGER PROTEIN 831 MONDO|Ensembl=ENSMODG00000021146.4|UniProtKB=A0A5F8GXG7 A0A5F8GXG7 RPS6KA4 PTHR24349:SF468 SERINE/THREONINE-PROTEIN KINASE RIBOSOMAL PROTEIN S6 KINASE, POLYPEPTIDE 4 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;calmodulin binding#GO:0005516;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000023957.3|UniProtKB=F6ZFU3 F6ZFU3 TRIM71 PTHR24104:SF55 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM71 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;RNA binding#GO:0003723;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;nucleic acid binding#GO:0003676;binding#GO:0005488;acyltransferase activity#GO:0016746 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;post-transcriptional regulation of gene expression#GO:0010608;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000012432.5|UniProtKB=F6PJX0 F6PJX0 PITPNM2 PTHR10658:SF41 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN MEMBRANE-ASSOCIATED PHOSPHATIDYLINOSITOL TRANSFER PROTEIN 2 transporter activity#GO:0005215;molecular carrier activity#GO:0140104;binding#GO:0005488;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol transfer activity#GO:0008526;phosphatidylcholine binding#GO:0031210;lipid carrier activity#GO:0005319;ion binding#GO:0043167;phosphatidylcholine intramembrane carrier activity#GO:0008525;small molecule binding#GO:0036094;anion binding#GO:0043168;cation binding#GO:0043169;intramembrane lipid carrier activity#GO:0140303 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transporter#PC00227 MONDO|Ensembl=ENSMODG00000024616.2|UniProtKB=F6PPL9 F6PPL9 PTHR43472:SF1 PHOSPHORIBOSYLAMINE--GLYCINE LIGASE PHOSPHORIBOSYLAMINE--GLYCINE LIGASE, CHLOROPLASTIC catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 ligase#PC00142 De novo purine biosynthesis#P02738>Phosphoribosylamine glycine ligase#P02908 MONDO|Ensembl=ENSMODG00000040655.1|UniProtKB=F7GLE7 F7GLE7 monDomV1R1242 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017110.4|UniProtKB=F6UK91 F6UK91 EGR2 PTHR23235:SF54 KRUEPPEL-LIKE TRANSCRIPTION FACTOR E3 SUMO-PROTEIN LIGASE EGR2 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008162.5|UniProtKB=F6R6H3 F6R6H3 PLCH2 PTHR10336:SF166 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE ETA-2 lipase activity#GO:0016298;hydrolase activity#GO:0016787;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 modulation of chemical synaptic transmission#GO:0050804;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;cell communication#GO:0007154;regulation of signaling#GO:0023051 metabolite interconversion enzyme#PC00262;phospholipase#PC00186;lipase#PC00143;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000015765.4|UniProtKB=F6PIR6 F6PIR6 KIF22 PTHR24115:SF1037 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF22 ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000007888.4|UniProtKB=F6YT90 F6YT90 DHRS9 PTHR43313:SF15 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 9 catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;oxoacid metabolic process#GO:0043436;isoprenoid biosynthetic process#GO:0008299;terpenoid metabolic process#GO:0006721;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;regulation of hormone levels#GO:0010817;monocarboxylic acid biosynthetic process#GO:0072330;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;diterpenoid biosynthetic process#GO:0016102;lipid biosynthetic process#GO:0008610;terpenoid biosynthetic process#GO:0016114;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;biosynthetic process#GO:0009058;cellular process#GO:0009987 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000013615.4|UniProtKB=F6VF13 F6VF13 ASPG PTHR11707:SF28 L-ASPARAGINASE 60 KDA LYSOPHOSPHOLIPASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;amidase activity#GO:0004040 MONDO|Ensembl=ENSMODG00000001056.4|UniProtKB=F6YRH4 F6YRH4 DARS1 PTHR43450:SF1 ASPARTYL-TRNA SYNTHETASE ASPARTATE--TRNA LIGASE, CYTOPLASMIC nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098 protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;cytosol#GO:0005829 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000002405.4|UniProtKB=F7EZZ5 F7EZZ5 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;cell communication#GO:0007154;regulation of immune response#GO:0050776;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000001737.4|UniProtKB=F6X050 F6X050 CNOT11 PTHR15975:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 CCR4-NOT complex#GO:0030014;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 MONDO|Ensembl=ENSMODG00000017572.3|UniProtKB=F7BSE2 F7BSE2 PMPCA PTHR11851:SF229 METALLOPROTEASE MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;macromolecule localization#GO:0033036 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;endopeptidase complex#GO:1905369;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000014967.4|UniProtKB=F7CGT6 F7CGT6 TTC39B PTHR31859:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39B negative regulation of cellular process#GO:0048523;regulation of lipid metabolic process#GO:0019216;chemical homeostasis#GO:0048878;cholesterol homeostasis#GO:0042632;regulation of localization#GO:0032879;regulation of transport#GO:0051049;lipid homeostasis#GO:0055088;regulation of metabolic process#GO:0019222;negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;homeostatic process#GO:0042592 MONDO|Ensembl=ENSMODG00000046345.1|UniProtKB=A0A5F8G7E4 A0A5F8G7E4 PTHR24377:SF710 IP01015P-RELATED ZINC FINGER PROTEIN 181-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000047754.1|UniProtKB=F6XKA3 F6XKA3 LOC100617675 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025665.3|UniProtKB=A0A5F8GQM3 A0A5F8GQM3 LOC100029540 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED MONDO|Ensembl=ENSMODG00000028476.2|UniProtKB=K7E363 K7E363 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000045591.1|UniProtKB=K7E4J2 K7E4J2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000004729.4|UniProtKB=A0A5F8GJS8 A0A5F8GJS8 GAB2 PTHR45960:SF1 GRB2-ASSOCIATED-BINDING PROTEIN GRB2-ASSOCIATED-BINDING PROTEIN 2 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;binding#GO:0005488;receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Grb2#P01148;EGF receptor signaling pathway#P00018>Gab#P00563 MONDO|Ensembl=ENSMODG00000018192.4|UniProtKB=F7B771 F7B771 TMEM39A PTHR12995:SF3 FI21814P1 TRANSMEMBRANE PROTEIN 39A regulation of macroautophagy#GO:0016241;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;regulation of autophagosome maturation#GO:1901096;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;negative regulation of macroautophagy#GO:0016242;regulation of protein-containing complex disassembly#GO:0043244;regulation of metabolic process#GO:0019222;negative regulation of catabolic process#GO:0009895;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of autophagosome assembly#GO:2000785;negative regulation of metabolic process#GO:0009892;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 MONDO|Gene=SNRPC|UniProtKB=F7ARS3 F7ARS3 SNRPC PTHR31148:SF1 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;cellular component assembly#GO:0022607;gene expression#GO:0010467;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;Sm-like protein family complex#GO:0120114;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;organelle#GO:0043226;U1 snRNP#GO:0005685;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000042016.1|UniProtKB=A0A5F8HBS3 A0A5F8HBS3 LOC100028052 PTHR10809:SF12 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN B_C protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum membrane organization#GO:0090158;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029 organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000028692.2|UniProtKB=K7E1P0 K7E1P0 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000047078.1|UniProtKB=A0A5F8HCA1 A0A5F8HCA1 AMER2 PTHR22237:SF1 APC MEMBRANE RECRUITMENT PROTEIN 2-RELATED APC MEMBRANE RECRUITMENT PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000025457.3|UniProtKB=F6RK69 F6RK69 PTHR12989:SF10 ALPHA-1,2-GLUCOSYLTRANSFERASE ALG10 DOL-P-GLC:GLC(2)MAN(9)GLCNAC(2)-PP-DOL ALPHA-1,2-GLUCOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transferase#PC00220 MONDO|Ensembl=ENSMODG00000010641.4|UniProtKB=F7D4U2 F7D4U2 NOL7 PTHR32337:SF2 NUCLEOLAR PROTEIN 7 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN NOL7 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000009811.3|UniProtKB=F6SG17 F6SG17 PUM2 PTHR12537:SF52 RNA BINDING PROTEIN PUMILIO-RELATED PUMILIO HOMOLOG 2 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000018901.3|UniProtKB=F7CQE9 F7CQE9 LOC100016035 PTHR23050:SF350 CALCIUM BINDING PROTEIN CENTRIN-4 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;cellular component organization or biogenesis#GO:0071840;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;centriole replication#GO:0007099;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000012697.4|UniProtKB=F6UYM6 F6UYM6 RESF1 PTHR21604:SF0 RETROELEMENT SILENCING FACTOR 1 RETROELEMENT SILENCING FACTOR 1 protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000013911.3|UniProtKB=F6VBM7 F6VBM7 PGAM2 PTHR11931:SF8 PHOSPHOGLYCERATE MUTASE PHOSPHOGLYCERATE MUTASE 2 phosphoglycerate mutase activity#GO:0004619;isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868 nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 isomerase#PC00135;mutase#PC00160 Glycolysis#P00024>Phosphoglyceromutase#P00680 MONDO|Ensembl=ENSMODG00000024859.2|UniProtKB=A0A5F8H9I8 A0A5F8H9I8 ANKRD34B PTHR24156:SF1 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 34B MONDO|Ensembl=ENSMODG00000000936.4|UniProtKB=A0A5F8GQI1 A0A5F8GQI1 LOC100015202 PTHR11481:SF97 IMMUNOGLOBULIN FC RECEPTOR LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR II-B-RELATED molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;protein-containing complex binding#GO:0044877;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049;response to stress#GO:0006950;cellular process#GO:0009987;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;immune system process#GO:0002376;positive regulation of cellular component organization#GO:0051130;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated cytotoxicity#GO:0001909;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;cell killing#GO:0001906;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;defense response#GO:0006952;positive regulation of gene expression#GO:0010628;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of endocytosis#GO:0045807;adaptive immune response#GO:0002250;biological regulation#GO:0065007;inflammatory response#GO:0006954;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;acute inflammatory response#GO:0002526;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000018997.4|UniProtKB=F7AMX7 F7AMX7 WRN PTHR13710:SF166 DNA HELICASE RECQ FAMILY MEMBER BIFUNCTIONAL 3'-5' EXONUCLEASE_ATP-DEPENDENT HELICASE WRN nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;telomere organization#GO:0032200;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA helicase#PC00011;DNA metabolism protein#PC00009 p53 pathway#P00059>WRN#P04617 MONDO|Ensembl=ENSMODG00000014689.4|UniProtKB=F7DN63 F7DN63 CWF19L2 PTHR12072:SF5 CWF19, CELL CYCLE CONTROL PROTEIN CWF19-LIKE PROTEIN 2 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000025301.2|UniProtKB=A0A5F8HL94 A0A5F8HL94 PTHR15718:SF6 G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH C-TERMINAL DOMAIN-CONTAINING PROTEIN G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH 3 developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;cellular component organization#GO:0016043;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000014919.5|UniProtKB=A0A5F8HA64 A0A5F8HA64 TSC22D1 PTHR46745:SF1 TSC22 DOMAIN FAMILY PROTEIN 1 TSC22 DOMAIN FAMILY PROTEIN 1 regulation of cell population proliferation#GO:0042127;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000018457.4|UniProtKB=F7CU55 F7CU55 PTHR35447:SF1 BH3-INTERACTING DOMAIN DEATH AGONIST BH3-INTERACTING DOMAIN DEATH AGONIST positive regulation of organelle organization#GO:0010638;positive regulation of signaling#GO:0023056;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;regulation of release of cytochrome c from mitochondria#GO:0090199;regulation of intracellular signal transduction#GO:1902531;regulation of cellular component organization#GO:0051128;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;regulation of organelle organization#GO:0033043;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;regulation of apoptotic process#GO:0042981;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of apoptotic signaling pathway#GO:2001233;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of mitochondrion organization#GO:0010821;regulation of intrinsic apoptotic signaling pathway#GO:2001242;cell death#GO:0008219;regulation of extrinsic apoptotic signaling pathway#GO:2001236;positive regulation of signal transduction#GO:0009967;programmed cell death#GO:0012501;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000023306.1|UniProtKB=F6VAU4 F6VAU4 PTHR11904:SF12 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740 purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside catabolic process#GO:0009164;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule catabolic process#GO:0034656;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;purine nucleoside metabolic process#GO:0042278;pyridine-containing compound metabolic process#GO:0072524;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 nucleotide kinase#PC00172;kinase#PC00137 Xanthine and guanine salvage pathway#P02788>Guanosine phosphorylase#P03250;Adenine and hypoxanthine salvage pathway#P02723>Deoxyinosine phosphorylase#P02812;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphorylase#P02805;Purine metabolism#P02769>Nucleoside Phosphorylase#P03115;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine phosphorylase#P02808;Adenine and hypoxanthine salvage pathway#P02723>Inosine phosphorylase#P02813;Xanthine and guanine salvage pathway#P02788>Deoxyguanosine phosphorylase#P03248 MONDO|Ensembl=ENSMODG00000003260.3|UniProtKB=F6T0U3 F6T0U3 ARK2C PTHR22937:SF233 E3 UBIQUITIN-PROTEIN LIGASE RNF165 E3 UBIQUITIN-PROTEIN LIGASE ARK2C ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 catabolic process#GO:0009056;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;system development#GO:0048731;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;plasma membrane bounded cell projection organization#GO:0120036;regulation of BMP signaling pathway#GO:0030510;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cellular process#GO:0048522;macromolecule metabolic process#GO:0043170;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;ubiquitin-dependent protein catabolic process#GO:0006511;neurogenesis#GO:0022008;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of response to stimulus#GO:0048583;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;proteasomal protein catabolic process#GO:0010498;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of BMP signaling pathway#GO:0030513;cell projection morphogenesis#GO:0048858;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000006567.4|UniProtKB=F7BUG9 F7BUG9 PTHR14162:SF1 MUCOSAL ADDRESSIN CELL ADHESION MOLECULE-1 MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1 cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;signaling receptor binding#GO:0005102;binding#GO:0005488;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cell communication#GO:0007154;immune system process#GO:0002376;cell adhesion#GO:0007155;cell motility#GO:0048870;regulation of cellular process#GO:0050794;heterotypic cell-cell adhesion#GO:0034113;response to stimulus#GO:0050896;signaling#GO:0023052;integrin-mediated signaling pathway#GO:0007229;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;cell surface receptor signaling pathway#GO:0007166;cell migration#GO:0016477;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;leukocyte cell-cell adhesion#GO:0007159;signal transduction#GO:0007165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000013839.4|UniProtKB=F6X6Q9 F6X6Q9 TCP11 PTHR12832:SF14 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 T-COMPLEX PROTEIN 11 HOMOLOG cell communication#GO:0007154;regulation of cell differentiation#GO:0045595;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of reproductive process#GO:2000241;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;signaling#GO:0023052;regulation of developmental process#GO:0050793;cellular response to stimulus#GO:0051716;regulation of cell development#GO:0060284;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;acrosomal vesicle#GO:0001669;cilium#GO:0005929;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;secretory vesicle#GO:0099503;sperm flagellum#GO:0036126;endomembrane system#GO:0012505;cytoplasm#GO:0005737 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000014702.4|UniProtKB=F7D3L8 F7D3L8 P3H4 PTHR13986:SF4 PROTEIN LYSINE HYDROXYLATION COMPLEX COMPONENT ENDOPLASMIC RETICULUM PROTEIN SC65 binding#GO:0005488;collagen binding#GO:0005518;protein-containing complex binding#GO:0044877 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000008936.4|UniProtKB=A0A5F8GSN4 A0A5F8GSN4 KCNH5 PTHR10217:SF533 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED DELAYED RECTIFIER POTASSIUM CHANNEL KCNH5 voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 transport#GO:0006810;regulation of membrane potential#GO:0042391;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000041512.1|UniProtKB=F6Q1R6 F6Q1R6 LOC100617863 PTHR26450:SF69 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56B1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016802.4|UniProtKB=F7FVJ6 F7FVJ6 DHTKD1 PTHR23152:SF38 2-OXOGLUTARATE DEHYDROGENASE 2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 metabolic process#GO:0008152;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091 membrane-enclosed lumen#GO:0031974;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000017617.4|UniProtKB=F6ZT98 F6ZT98 COL9A2 PTHR24023:SF906 COLLAGEN ALPHA COLLAGEN ALPHA-2(IX) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000007872.4|UniProtKB=A0A5F8H0B7 A0A5F8H0B7 SVIL PTHR11977:SF45 VILLIN SUPERVILLIN cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;actin binding#GO:0003779;actin filament binding#GO:0051015;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936 negative regulation of biological process#GO:0048519;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of actin filament depolymerization#GO:0030834;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000008633.3|UniProtKB=F6PGM1 F6PGM1 SIX6 PTHR10390:SF12 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX6 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;visual system development#GO:0150063;animal gross anatomical part developmental process#GO:0160108;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;eye development#GO:0001654;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;sensory system development#GO:0048880;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000005007.4|UniProtKB=F7F6Z3 F7F6Z3 TXNDC11 PTHR46497:SF1 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000039094.1|UniProtKB=A0A5F8H0M3 A0A5F8H0M3 LOC103098957 PTHR22802:SF14 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER K binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000017760.3|UniProtKB=F7E4L7 F7E4L7 PDIA3 PTHR18929:SF257 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A3 catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;catalytic activity, acting on a protein#GO:0140096;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853 response to stress#GO:0006950;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;response to stimulus#GO:0050896;protein folding#GO:0006457;biosynthetic process#GO:0009058;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell surface#GO:0009986;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000000168.2|UniProtKB=F6XA47 F6XA47 MRPS16 PTHR12919:SF41 30S RIBOSOMAL PROTEIN S16 SMALL RIBOSOMAL SUBUNIT PROTEIN BS16M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000038898.1|UniProtKB=A0A5F8GBW8 A0A5F8GBW8 DCTN4 PTHR13034:SF2 DYNACTIN P62 SUBUNIT DYNACTIN SUBUNIT 4 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;transport#GO:0006810;intracellular transport#GO:0046907 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630 microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000040553.1|UniProtKB=A0A5F8GPR5 A0A5F8GPR5 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000023047.3|UniProtKB=F7C0P9 F7C0P9 PTHR24376:SF258 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 814 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000020355.4|UniProtKB=A0A5F8HDG5 A0A5F8HDG5 RANBP3L PTHR23138:SF88 RAN BINDING PROTEIN RAN-BINDING PROTEIN 3-LIKE nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein transport#GO:0015031;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein export from nucleus#GO:0006611;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018393.4|UniProtKB=A0A5F8GGR2 A0A5F8GGR2 FYTTD1 PTHR21038:SF2 40-2-3 PROTEIN-RELATED UAP56-INTERACTING FACTOR protein-RNA adaptor activity#GO:0140517;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000012651.4|UniProtKB=F6WDN7 F6WDN7 FBXO47 PTHR34098:SF1 F-BOX ONLY PROTEIN 47 F-BOX ONLY PROTEIN 47 MONDO|Ensembl=ENSMODG00000005218.3|UniProtKB=F7A1S6 F7A1S6 PHLPP1 PTHR45752:SF58 LEUCINE-RICH REPEAT-CONTAINING PH DOMAIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN PHOSPHATASE 1 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014529.4|UniProtKB=F7ER43 F7ER43 KRT36 PTHR23239:SF204 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA6 structural molecule activity#GO:0005198 cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009;developmental process#GO:0032502 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000000781.4|UniProtKB=F7CR18 F7CR18 NCAPG PTHR14418:SF5 CONDENSIN COMPLEX SUBUNIT 3-RELATED CONDENSIN COMPLEX SUBUNIT 3 mitotic chromosome condensation#GO:0007076;chromosome condensation#GO:0030261;organelle fission#GO:0048285;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070 nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;condensin complex#GO:0000796;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000037547.1|UniProtKB=F6W0Z0 F6W0Z0 PTHR13011:SF0 TFIIF-ALPHA GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1 RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488;transcription factor binding#GO:0008134 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIFalpha#P00663;Transcription regulation by bZIP transcription factor#P00055>TFIIFalpha#P01391 MONDO|Ensembl=ENSMODG00000010764.4|UniProtKB=F7FK61 F7FK61 NOL4 PTHR12449:SF17 DEATH DOMAIN-CONTAINING PROTEIN NUCLEOLAR PROTEIN 4 MONDO|Ensembl=ENSMODG00000011525.4|UniProtKB=F6QXZ5 F6QXZ5 IL13RA1 PTHR23036:SF89 CYTOKINE RECEPTOR INTERLEUKIN-13 RECEPTOR SUBUNIT ALPHA-1 cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 MONDO|Ensembl=ENSMODG00000018989.3|UniProtKB=F7FNZ9 F7FNZ9 MRPL2 PTHR13691:SF73 RIBOSOMAL PROTEIN L2 LARGE RIBOSOMAL SUBUNIT PROTEIN UL2M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;cytosolic large ribosomal subunit#GO:0022625;mitochondrion#GO:0005739;ribosome#GO:0005840 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000020893.4|UniProtKB=H9H7Q7 H9H7Q7 PTHR13902:SF47 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK3 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;transferase activity#GO:0016740;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;protein serine/threonine kinase activity#GO:0004674;molecular function inhibitor activity#GO:0140678;protein kinase activity#GO:0004672;channel regulator activity#GO:0016247;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;regulation of localization#GO:0032879;regulation of transport#GO:0051049;chemical homeostasis#GO:0048878;regulation of monoatomic cation transmembrane transport#GO:1904062;signaling#GO:0023052;homeostatic process#GO:0042592;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;regulation of transmembrane transport#GO:0034762;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000019050.4|UniProtKB=A0A5F8H1R2 A0A5F8H1R2 SLC7A2 PTHR43243:SF35 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 transport#GO:0006810;amino acid transport#GO:0006865;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;amino acid transporter#PC00046 MONDO|Ensembl=ENSMODG00000012381.4|UniProtKB=F6PQ82 F6PQ82 TYW5 PTHR12461:SF104 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 5 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;dioxygenase activity#GO:0051213;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on RNA#GO:0140098 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000002087.4|UniProtKB=F6UZ64 F6UZ64 MAPKAPK2 PTHR24349:SF63 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-ACTIVATED PROTEIN KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity#GO:0016740;calmodulin binding#GO:0005516;mitogen-activated protein kinase binding#GO:0051019;enzyme binding#GO:0019899;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515 innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of response to biotic stimulus#GO:0002831;regulation of defense response#GO:0031347;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of immune response#GO:0050776;inflammatory response#GO:0006954;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;positive regulation of response to biotic stimulus#GO:0002833;vascular endothelial growth factor receptor signaling pathway#GO:0048010;response to endogenous stimulus#GO:0009719;toll-like receptor signaling pathway#GO:0002224;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;immune system process#GO:0002376;response to peptide#GO:1901652;cellular response to growth factor stimulus#GO:0071363;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;regulation of response to external stimulus#GO:0032101;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Angiogenesis#P00005>MAPKAPK2/3#P00244;p38 MAPK pathway#P05918>MAPKAP-K2#P05920;Interleukin signaling pathway#P00036>MAPKAPK2#P00979;Ras Pathway#P04393>MAPKAP#P04564;PDGF signaling pathway#P00047>MAPKAPK2#P01157;VEGF signaling pathway#P00056>MAPKAPK2/3#P01415 MONDO|Ensembl=ENSMODG00000010880.4|UniProtKB=F7FVW8 F7FVW8 PLOD1 PTHR10730:SF5 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE 1 catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000012769.4|UniProtKB=F6SIL0 F6SIL0 ANKS6 PTHR10627:SF70 SCP160 ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 6 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000007917.3|UniProtKB=F7GID4 F7GID4 PTHR23226:SF127 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 24 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000043722.1|UniProtKB=A0A5F8GYH6 A0A5F8GYH6 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000019574.4|UniProtKB=F6QN45 F6QN45 ATP6V1G1 PTHR12713:SF12 VACUOLAR ATP SYNTHASE SUBUNIT G V-TYPE PROTON ATPASE SUBUNIT G 1 homeostatic process#GO:0042592;cellular component organization#GO:0016043;transmembrane transport#GO:0055085;cellular localization#GO:0051641;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;vesicle-mediated transport#GO:0016192;developmental maturation#GO:0021700;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;synaptic vesicle maturation#GO:0016188;proton transmembrane transport#GO:1902600;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;cellular homeostasis#GO:0019725;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;developmental process#GO:0032502 ATPase dependent transmembrane transport complex#GO:0098533;exocytic vesicle#GO:0070382;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular vesicle#GO:0097708;transporter complex#GO:1990351;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;proton-transporting two-sector ATPase complex#GO:0016469;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vacuole#GO:0005773;secretory vesicle#GO:0099503;presynapse#GO:0098793;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000010119.4|UniProtKB=F6WNP3 F6WNP3 VPS51 PTHR15954:SF4 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;cellular component organization#GO:0016043;cytosolic transport#GO:0016482;endocytic recycling#GO:0032456;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;vesicle tethering complex#GO:0099023;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000046676.1|UniProtKB=A0A5F8H1M9 A0A5F8H1M9 PTHR23226:SF425 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 24 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000007500.4|UniProtKB=F7GK27 F7GK27 RUNX1T1 PTHR10379:SF5 MTG8 ETO EIGHT TWENTY ONE PROTEIN PROTEIN CBFA2T1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000019719.4|UniProtKB=A0A5F8G504 A0A5F8G504 HOMER1 PTHR10918:SF3 HOMER HOMER PROTEIN HOMOLOG 1 signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 signal transduction#GO:0007165;cellular process#GO:0009987;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;cell surface receptor signaling pathway#GO:0007166;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of metal ion transport#GO:0010959;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;glutamate receptor signaling pathway#GO:0007215;cell communication#GO:0007154 cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622;postsynapse#GO:0098794;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279 Metabotropic glutamate receptor group I pathway#P00041>Homer#P01058 MONDO|Ensembl=ENSMODG00000011511.3|UniProtKB=F6UIU3 F6UIU3 LOC100023364 PTHR26450:SF89 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52B4 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004155.4|UniProtKB=A0A5F8GKJ6 A0A5F8GKJ6 PLAA PTHR19849:SF7 PHOSPHOLIPASE A-2-ACTIVATING PROTEIN PHOSPHOLIPASE A-2-ACTIVATING PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;autophagy#GO:0006914;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;cellular process#GO:0009987;regulation of localization#GO:0032879;regulation of transport#GO:0051049;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to stimulus#GO:0050896;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;macroautophagy#GO:0016236;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;macromolecule metabolic process#GO:0043170;positive regulation of locomotion#GO:0040017;defense response#GO:0006952;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of neuron migration#GO:2001222;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of cell migration#GO:0030334;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of cell motility#GO:2000145;protein metabolic process#GO:0019538;inflammatory response#GO:0006954 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000007250.2|UniProtKB=F6VWW2 F6VWW2 LOC100012932 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016974.3|UniProtKB=F6UM87 F6UM87 GMEB2 PTHR10417:SF2 GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN 2 transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000051610.1|UniProtKB=A0A5F8GMT3 A0A5F8GMT3 NDUFB4 PTHR15469:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B15 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 4 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000013263.4|UniProtKB=F7D9Y3 F7D9Y3 ABCG4 PTHR48041:SF75 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;chemical homeostasis#GO:0048878;sterol transport#GO:0015918;cholesterol homeostasis#GO:0042632;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;cholesterol efflux#GO:0033344;cellular process#GO:0009987;lipid transport#GO:0006869;lipid localization#GO:0010876;localization#GO:0051179;transmembrane transport#GO:0055085;organic hydroxy compound transport#GO:0015850;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000014263.3|UniProtKB=F6XIV3 F6XIV3 ALKAL2 PTHR28676:SF2 ALK AND LTK LIGAND 2-RELATED ALK AND LTK LIGAND 2 signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;kinase activator activity#GO:0019209;protein kinase activator activity#GO:0030295;receptor tyrosine kinase binding#GO:0030971;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207 positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967 MONDO|Ensembl=ENSMODG00000007000.4|UniProtKB=F6XUF8 F6XUF8 RGS6 PTHR45746:SF2 LP21163P REGULATOR OF G PROTEIN SIGNALING 6 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 MONDO|Ensembl=ENSMODG00000044017.1|UniProtKB=A0A5F8GJC3 A0A5F8GJC3 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024902.2|UniProtKB=F6WTQ2 F6WTQ2 PTHR24072:SF153 RHO FAMILY GTPASE TRANSFORMING PROTEIN RHOA GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of actin cytoskeleton organization#GO:0032956;intracellular signaling cassette#GO:0141124;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;actin filament bundle organization#GO:0061572;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;actomyosin structure organization#GO:0031032;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;Rho protein signal transduction#GO:0007266;stress fiber assembly#GO:0043149;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cell migration#GO:0016477;contractile actin filament bundle assembly#GO:0030038;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;cellular response to stimulus#GO:0051716;actin filament bundle assembly#GO:0051017;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;intracellular signal transduction#GO:0035556;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154 plasma membrane region#GO:0098590;cell division site#GO:0032153;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cleavage furrow#GO:0032154;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;postsynapse#GO:0098794;dendritic spine#GO:0043197;intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;dendritic tree#GO:0097447 G-protein#PC00020;small GTPase#PC00208 Integrin signalling pathway#P00034>Rho#P00948;Ras Pathway#P04393>Rho#P04578;CCKR signaling map#P06959>RHOA-GDP#P07019;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoA#P00740;Axon guidance mediated by semaphorins#P00007>Rho#P00341;CCKR signaling map#P06959>RHOA-GTP#P07188;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rho#P00860;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>RhoA#P05938;Angiogenesis#P00005>GTPase#P00254 MONDO|Ensembl=ENSMODG00000041988.1|UniProtKB=A0A5F8HCF9 A0A5F8HCF9 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000041838.1|UniProtKB=A0A5F8H865 A0A5F8H865 PTHR10965:SF0 60S RIBOSOMAL PROTEIN L38 LARGE RIBOSOMAL SUBUNIT PROTEIN EL38 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000051240.1|UniProtKB=A0A5F8GGZ5 A0A5F8GGZ5 LOC654275 PTHR10454:SF198 CASPASE CASPASE-3 molecular function regulator activity#GO:0098772;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;enzyme activator activity#GO:0008047;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;molecular function activator activity#GO:0140677;hydrolase activity#GO:0016787;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;positive regulation of cellular process#GO:0048522;neurogenesis#GO:0022008;multicellular organismal-level homeostasis#GO:0048871;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;epidermis development#GO:0008544;positive regulation of neuron apoptotic process#GO:0043525;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;cell death#GO:0008219;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;system development#GO:0048731;erythrocyte differentiation#GO:0030218;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;homeostasis of number of cells#GO:0048872;keratinocyte differentiation#GO:0030216;nervous system development#GO:0007399;skin development#GO:0043588;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron apoptotic process#GO:0043523;animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;neuron differentiation#GO:0030182;metabolic process#GO:0008152;cell development#GO:0048468;myeloid cell differentiation#GO:0030099;positive regulation of programmed cell death#GO:0043068;cell differentiation#GO:0030154;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;proteolysis#GO:0006508;immune system process#GO:0002376 intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;protease#PC00190 CCKR signaling map#P06959>Pro-caspase-3#P07231;Apoptosis signaling pathway#P00006>Caspase 3#P00305;FAS signaling pathway#P00020>Caspase3#P00599;CCKR signaling map#P06959>Caspase-3#P07108;FAS signaling pathway#P00020>Pro-Caspase3#P00608;Huntington disease#P00029>Caspase 3#P00812 MONDO|Ensembl=ENSMODG00000000418.4|UniProtKB=F7EWT8 F7EWT8 ARHGAP40 PTHR14963:SF4 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 40 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of small GTPase mediated signal transduction#GO:0051056;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GTPase-activating protein#PC00257;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000014763.4|UniProtKB=F7GGT3 F7GGT3 PTHR23409:SF20 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 biosynthetic process#GO:0009058;cellular process#GO:0009987;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;reductase#PC00198;oxidoreductase#PC00176 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921;De novo purine biosynthesis#P02738>GDP reductase#P02909;p53 pathway#P00059>R2#G04692;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915 MONDO|Ensembl=ENSMODG00000007280.4|UniProtKB=F7FQK6 F7FQK6 PDE3B PTHR11347:SF29 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057 hydrolase#PC00121;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000019159.4|UniProtKB=F7BK23 F7BK23 LOC103093843 PTHR12015:SF183 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 26-RELATED leukocyte chemotaxis#GO:0030595;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;leukocyte migration#GO:0050900;cell migration#GO:0016477;granulocyte migration#GO:0097530;response to chemical#GO:0042221;taxis#GO:0042330;cellular process#GO:0009987;cell chemotaxis#GO:0060326;chemotaxis#GO:0006935;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;locomotion#GO:0040011;cell motility#GO:0048870;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;cellular response to stimulus#GO:0051716 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000012975.4|UniProtKB=F7DB85 F7DB85 SETD3 PTHR13271:SF159 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE ACTIN-HISTIDINE N-METHYLTRANSFERASE lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276 regulation of muscle system process#GO:0090257;regulation of system process#GO:0044057;regulation of muscle contraction#GO:0006937;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of smooth muscle contraction#GO:0006940;regulation of multicellular organismal process#GO:0051239 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000003978.3|UniProtKB=F7FMD0 F7FMD0 ARL5A PTHR11711:SF147 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 5A nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;protein localization to membrane#GO:0072657;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein localization to Golgi apparatus#GO:0034067;intracellular protein transport#GO:0006886;transport#GO:0006810;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231 G-protein#PC00020 MONDO|Ensembl=ENSMODG00000051481.1|UniProtKB=K7E2P4 K7E2P4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000002597.5|UniProtKB=A0A5F8GVJ9 A0A5F8GVJ9 RCSD1 PTHR21669:SF2 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS CAPZ-INTERACTING PROTEIN phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289 protein localization to organelle#GO:0033365;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810 intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017713.4|UniProtKB=F7FHU1 F7FHU1 POU3F1 PTHR11636:SF75 POU DOMAIN POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000007560.4|UniProtKB=F7G005 F7G005 TRAPPC1 PTHR23249:SF16 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 1 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000016462.4|UniProtKB=F7F1F8 F7F1F8 ZSCAN10 PTHR24377:SF369 IP01015P-RELATED ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 10 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018430.3|UniProtKB=F6XC44 F6XC44 SLC51A PTHR23423:SF11 ORGANIC SOLUTE TRANSPORTER-RELATED ORGANIC SOLUTE TRANSPORTER SUBUNIT ALPHA transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 lipid transport#GO:0006869;macromolecule localization#GO:0033036;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;localization#GO:0051179;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;bile acid and bile salt transport#GO:0015721;lipid localization#GO:0010876 organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000025440.3|UniProtKB=F6S5E8 F6S5E8 PTHR16435:SF5 SPERMATOGENESIS-ASSOCIATED PROTEIN 6 SPATA6 SPERMATOGENESIS ASSOCIATED 6-LIKE PROTEIN MONDO|Ensembl=ENSMODG00000024581.1|UniProtKB=F7B6G1 F7B6G1 LOC100030062 PTHR48018:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 974 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038693.1|UniProtKB=A0A5F8H6J2 A0A5F8H6J2 RERG PTHR24070:SF373 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED AND ESTROGEN-REGULATED GROWTH INHIBITOR hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 Ras protein signal transduction#GO:0007265;establishment or maintenance of cell polarity#GO:0007163;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 PDGF signaling pathway#P00047>Ras#P01154 MONDO|Ensembl=ENSMODG00000013531.4|UniProtKB=A0A5F8GRD6 A0A5F8GRD6 STK32C PTHR24356:SF153 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 32C protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000024277.2|UniProtKB=F6Z5B9 F6Z5B9 LOC100016274 PTHR48018:SF72 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8D1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027565.2|UniProtKB=F7DP37 F7DP37 PTHR12681:SF0 ZINC FINGER-CONTAINING PROTEIN P48ZNF ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 15 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000019277.4|UniProtKB=F6SHF4 F6SHF4 ST8SIA4 PTHR11987:SF48 ALPHA-2,8-SIALYLTRANSFERASE CMP-N-ACETYLNEURAMINATE-POLY-ALPHA-2,8-SIALYLTRANSFERASE glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;oligosaccharide metabolic process#GO:0009311;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000038167.1|UniProtKB=F7BPG0 F7BPG0 H2AX PTHR23430:SF199 HISTONE H2A HISTONE H2AX structural molecule activity#GO:0005198 cellular response to stress#GO:0033554;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000047406.1|UniProtKB=A0A5F8G8P4 A0A5F8G8P4 LOC100031231 PTHR24249:SF220 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227 cell communication#GO:0007154;defense response#GO:0006952;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signaling#GO:0023052;response to stress#GO:0006950;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000020386.4|UniProtKB=F7C078 F7C078 BRIX1 PTHR13634:SF0 RIBOSOME BIOGENESIS PROTEIN BRIX RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;ribosomal large subunit assembly#GO:0000027;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000009878.4|UniProtKB=F6VTR9 F6VTR9 PTHR20838:SF0 LYMPHOCYTE ANTIGEN 86 LYMPHOCYTE ANTIGEN 86 positive regulation of signaling#GO:0023056;immune system process#GO:0002376;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of response to external stimulus#GO:0032103;innate immune response#GO:0045087;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;defense response#GO:0006952;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;immune response#GO:0006955;defense response to symbiont#GO:0140546 MONDO|Ensembl=ENSMODG00000021137.2|UniProtKB=F6QWG6 F6QWG6 LOC100618976 PTHR26453:SF102 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2L13 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015207.4|UniProtKB=F7B9T0 F7B9T0 TRAK2 PTHR15751:SF13 TRAFFICKING KINESIN-BINDING PROTEIN TRAFFICKING KINESIN-BINDING PROTEIN 2 cytoskeletal protein binding#GO:0008092;signaling receptor binding#GO:0005102;myosin binding#GO:0017022;binding#GO:0005488;GABA receptor binding#GO:0050811;protein binding#GO:0005515 cell differentiation#GO:0030154;establishment of organelle localization#GO:0051656;protein targeting#GO:0006605;cellular localization#GO:0051641;animal gross anatomical part developmental process#GO:0160108;microtubule-based transport#GO:0099111;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;nervous system development#GO:0007399;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;multicellular organism development#GO:0007275;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;organelle localization#GO:0051640;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle localization#GO:0051648;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;vesicle cytoskeletal trafficking#GO:0099518;neurogenesis#GO:0022008;mitochondrion localization#GO:0051646;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;developmental process#GO:0032502;transport#GO:0006810 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular vesicle#GO:0097708;vesicle#GO:0031982;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000020977.4|UniProtKB=F6S5B1 F6S5B1 GRIK1 PTHR18966:SF36 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 1 metal ion transmembrane transporter activity#GO:0046873;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;molecular transducer activity#GO:0060089;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943 synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268 plasma membrane protein complex#GO:0098797;postsynapse#GO:0098794;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;transporter complex#GO:1990351;cell junction#GO:0030054 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group I pathway#P00041>GluR5#P01054;Ionotropic glutamate receptor pathway#P00037>KA1#P01004;Ionotropic glutamate receptor pathway#P00037>KA#P01026 MONDO|Ensembl=ENSMODG00000024890.2|UniProtKB=F6RYU7 F6RYU7 LYRM7 PTHR46749:SF1 COMPLEX III ASSEMBLY FACTOR LYRM7 COMPLEX III ASSEMBLY FACTOR LYRM7 cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrion organization#GO:0007005 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000016574.4|UniProtKB=H9H6Z7 H9H6Z7 PMM1 PTHR10466:SF1 PHOSPHOMANNOMUTASE PHOSPHOMANNOMUTASE 1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868 glycoprotein metabolic process#GO:0009100;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 mutase#PC00160;isomerase#PC00135;metabolite interconversion enzyme#PC00262 Mannose metabolism#P02752>P-Mannose mutase#P03019 MONDO|Ensembl=ENSMODG00000007772.4|UniProtKB=F7AWY8 F7AWY8 ARFGEF1 PTHR10663:SF137 GUANYL-NUCLEOTIDE EXCHANGE FACTOR BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 1 cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus subcompartment#GO:0098791;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000047031.1|UniProtKB=A0A5F8GGL9 A0A5F8GGL9 TSNAX PTHR10741:SF5 TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X TRANSLIN-ASSOCIATED PROTEIN X endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000021145.4|UniProtKB=H9H7V3 H9H7V3 LOC100031337 PTHR24064:SF717 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 12-LIKE transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000009667.3|UniProtKB=F6SHS6 F6SHS6 LUM PTHR45712:SF6 AGAP008170-PA LUMICAN binding#GO:0005488;collagen binding#GO:0005518;protein-containing complex binding#GO:0044877 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000038826.1|UniProtKB=A0A5F8G2D7 A0A5F8G2D7 RIPPLY2 PTHR16770:SF3 PROTEIN RIPPLY-LIKE PROTEIN RIPPLY2 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule biosynthetic process#GO:0010558;embryonic pattern specification#GO:0009880;embryo development#GO:0009790;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000019309.3|UniProtKB=F6RYA5 F6RYA5 PLAC8 PTHR15907:SF32 DUF614 FAMILY PROTEIN-RELATED PLACENTA-SPECIFIC GENE 8 PROTEIN regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 MONDO|Ensembl=ENSMODG00000002614.4|UniProtKB=F7G4L6 F7G4L6 ACSS2 PTHR24095:SF126 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE, CYTOPLASMIC ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;acetyl-CoA metabolic process#GO:0006084;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;nucleoside phosphate biosynthetic process#GO:1901293;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ligase#PC00142 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 MONDO|Ensembl=ENSMODG00000001318.4|UniProtKB=F7BDV8 F7BDV8 TSGA10 PTHR23159:SF14 CENTROSOMAL PROTEIN 2 TESTIS-SPECIFIC GENE 10 PROTEIN cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;centriole replication#GO:0007099;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000004576.4|UniProtKB=F6R4C7 F6R4C7 SRPRA PTHR43134:SF1 SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein-containing complex binding#GO:0044877;hydrolase activity#GO:0016787;ribonucleoprotein complex binding#GO:0043021;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111 protein targeting to ER#GO:0045047;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting#GO:0006605;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;establishment of protein localization#GO:0045184 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 G-protein#PC00020;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000005764.4|UniProtKB=F6U8U6 F6U8U6 PTHR12228:SF0 TRANSCRIPTION INITIATION FACTOR TFIID 55 KD SUBUNIT-RELATED TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 7 RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 MONDO|Ensembl=ENSMODG00000004714.3|UniProtKB=F6QGJ3 F6QGJ3 DDX41 PTHR47958:SF103 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX41-RELATED nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000039109.1|UniProtKB=A0A5F8GUI1 A0A5F8GUI1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000013455.3|UniProtKB=F7G996 F7G996 PTHR23239:SF215 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 28 structural molecule activity#GO:0005198 morphogenesis of an epithelium#GO:0002009;cellular developmental process#GO:0048869;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;epidermis development#GO:0008544;skin development#GO:0043588;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cellular process#GO:0009987;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;intermediate filament organization#GO:0045109;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000013708.5|UniProtKB=F6Y9H8 F6Y9H8 FCGBP PTHR11339:SF373 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED IGGFC-BINDING PROTEIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000007749.4|UniProtKB=F7BJT0 F7BJT0 AP5M1 PTHR16082:SF2 AP-5 COMPLEX SUBUNIT MU-1 AP-5 COMPLEX SUBUNIT MU-1 endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 lytic vacuole#GO:0000323;AP-type membrane coat adaptor complex#GO:0030119;cytosol#GO:0005829;membrane#GO:0016020;endomembrane system#GO:0012505;late endosome#GO:0005770;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000005716.3|UniProtKB=F6U3M3 F6U3M3 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000002929.3|UniProtKB=F6PMG6 F6PMG6 TRAFD1 PTHR16295:SF19 TRAF-TYPE ZINC FINGER PROTEIN-RELATED TRAF-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of innate immune response#GO:0045088;negative regulation of innate immune response#GO:0045824;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of response to external stimulus#GO:0032102;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;negative regulation of immune response#GO:0050777;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of response to biotic stimulus#GO:0002831;negative regulation of defense response#GO:0031348;regulation of immune system process#GO:0002682 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000003488.2|UniProtKB=A0A5F8HG77 A0A5F8HG77 EMC9 PTHR12941:SF12 ER MEMBRANE PROTEIN COMPLEX ER MEMBRANE PROTEIN COMPLEX SUBUNIT 9 molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597 localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000042942.1|UniProtKB=A0A5F8GDU6 A0A5F8GDU6 CFAP97D2 PTHR23035:SF2 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97 MONDO|Ensembl=ENSMODG00000003377.4|UniProtKB=F6YST9 F6YST9 DAB1 PTHR47695:SF4 PID DOMAIN-CONTAINING PROTEIN DISABLED HOMOLOG 1 system development#GO:0048731;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;neuron migration#GO:0001764;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;developmental process#GO:0032502;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;cell differentiation#GO:0030154;cell migration#GO:0016477;cell motility#GO:0048870;multicellular organismal process#GO:0032501;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000045440.1|UniProtKB=A0A5F8GUY3 A0A5F8GUY3 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000012068.4|UniProtKB=F7G536 F7G536 LRRK1 PTHR23257:SF986 SERINE-THREONINE PROTEIN KINASE LEUCINE-RICH REPEAT SERINE_THREONINE-PROTEIN KINASE 1 catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000017275.4|UniProtKB=A0A5F8HAF6 A0A5F8HAF6 MYPN PTHR13817:SF67 TITIN MYOPALLADIN structural molecule activity#GO:0005198 developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;myofibril assembly#GO:0030239;anatomical structure morphogenesis#GO:0009653;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;contractile muscle fiber#GO:0043292;A band#GO:0031672;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular organelle#GO:0043229;M band#GO:0031430 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000018705.4|UniProtKB=F7FCL5 F7FCL5 SEC22B PTHR45837:SF3 VESICLE-TRAFFICKING PROTEIN SEC22B VESICLE-TRAFFICKING PROTEIN SEC22B SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;Golgi membrane#GO:0000139;coated vesicle membrane#GO:0030662;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular vesicle#GO:0097708;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;ER to Golgi transport vesicle membrane#GO:0012507;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;vesicle#GO:0031982;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum subcompartment#GO:0098827 MONDO|Ensembl=ENSMODG00000019049.4|UniProtKB=F7AYD0 F7AYD0 PDGFRL PTHR15360:SF1 PLATELET-DERIVED GROWTH FACTOR RECEPTOR LIKE PLATELET-DERIVED GROWTH FACTOR RECEPTOR-LIKE PROTEIN tyrosine protein kinase receptor#PC00233 PDGF signaling pathway#P00047>PDGF receptor A#P01158;PDGF signaling pathway#P00047>PDGF receptor B#P01156 MONDO|Ensembl=ENSMODG00000039437.1|UniProtKB=K7E3G9 K7E3G9 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000025349.2|UniProtKB=F6YLS8 F6YLS8 PTHR12002:SF4 CLAUDIN CLAUDIN-34 cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216 apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000025329.2|UniProtKB=A0A5F8G7D1 A0A5F8G7D1 PTHR28342:SF1 MONOOXYGENASE P33MONOX-RELATED MONOOXYGENASE P33MONOX-RELATED intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000025554.3|UniProtKB=F6UIK7 F6UIK7 APOO PTHR14564:SF2 MICOS COMPLEX SUBUNIT MIC26 / MIC27 FAMILY MEMBER MICOS COMPLEX SUBUNIT MIC26 mitochondrial membrane organization#GO:0007006;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966 MONDO|Ensembl=ENSMODG00000004515.4|UniProtKB=F6VXR9 F6VXR9 AGFG2 PTHR46134:SF4 DRONGO, ISOFORM F ARF-GAP DOMAIN AND FG REPEAT-CONTAINING PROTEIN 2 reproductive process#GO:0022414;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;spermatid development#GO:0007286;sexual reproduction#GO:0019953;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;male gamete generation#GO:0048232;nucleus organization#GO:0006997;cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;acrosome assembly#GO:0001675;intermediate filament organization#GO:0045109;spermatid differentiation#GO:0048515;intermediate filament-based process#GO:0045103;cytoskeleton organization#GO:0007010;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;vesicle organization#GO:0016050;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000006111.3|UniProtKB=F7EIF9 F7EIF9 TTLL2 PTHR12241:SF118 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL2-RELATED catalytic activity, acting on a protein#GO:0140096;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;tubulin binding#GO:0015631;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515;binding#GO:0005488 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000039493.1|UniProtKB=A0A5F8GRZ9 A0A5F8GRZ9 PTHR12015:SF147 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 13 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;cellular response to chemokine#GO:1990869;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326;cytokine-mediated signaling pathway#GO:0019221;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cell migration#GO:0016477;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to peptide#GO:1901652;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to chemical#GO:0042221;taxis#GO:0042330;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;granulocyte migration#GO:0097530;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;response to stress#GO:0006950;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000013953.3|UniProtKB=F6RT62 F6RT62 PDYN PTHR11438:SF4 PROENKEPHALIN PROENKEPHALIN-B molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 system process#GO:0003008;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;sensory perception of pain#GO:0019233 secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;neuronal cell body#GO:0043025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;cell body#GO:0044297;intracellular vesicle#GO:0097708;organelle lumen#GO:0043233;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;endomembrane system#GO:0012505;secretory vesicle#GO:0099503;membrane-enclosed lumen#GO:0031974 intercellular signal molecule#PC00207;peptide hormone#PC00179;neuropeptide#PC00162 Enkephalin release#P05913>Enkephalin#P05976;Opioid prodynorphin pathway#P05916>prodynorphin#P05997;Opioid prodynorphin pathway#P05916>dynorphin#P06003;Enkephalin release#P05913>preproenkephalin#G06045;Enkephalin release#P05913>preproenkephalin mRNA#G06046;Opioid prodynorphin pathway#P05916>preprodynorphin#G06049;Opioid proenkephalin pathway#P05915>Enkephalin#P05991;Opioid prodynorphin pathway#P05916>preprodynorphin#G06047 MONDO|Ensembl=ENSMODG00000023314.2|UniProtKB=F6RSG9 F6RSG9 LOC100031219 PTHR24249:SF271 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 6 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000019164.4|UniProtKB=F7BJP5 F7BJP5 ALB PTHR11385:SF15 SERUM ALBUMIN-RELATED ALBUMIN heterocyclic compound binding#GO:1901363;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 response to stimulus#GO:0050896;response to nutrient levels#GO:0031667 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000007933.4|UniProtKB=F7G957 F7G957 WEE1 PTHR11042:SF72 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED WEE1-LIKE PROTEIN KINASE protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 negative regulation of mitotic cell cycle#GO:0045930;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000004028.4|UniProtKB=F7CMX9 F7CMX9 ARMC6 PTHR22895:SF9 ARMADILLO REPEAT-CONTAINING PROTEIN 6 ARMADILLO REPEAT-CONTAINING PROTEIN 6 cellular process#GO:0009987;developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cell development#GO:0048468;hemopoiesis#GO:0030097 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000024830.3|UniProtKB=F7F9Q2 F7F9Q2 LOC100015966 PTHR11818:SF145 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN D structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;sensory system development#GO:0048880;multicellular organism development#GO:0007275;animal organ development#GO:0048513;system process#GO:0003008;sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;visual perception#GO:0007601;visual system development#GO:0150063;sensory perception of light stimulus#GO:0050953;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;sensory perception#GO:0007600;nervous system process#GO:0050877 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000039603.1|UniProtKB=A0A5F8GX42 A0A5F8GX42 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000050792.1|UniProtKB=A0A5F8GYS5 A0A5F8GYS5 CLDN5 PTHR12002:SF35 CLAUDIN CLAUDIN-5 cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;apical junction complex#GO:0043296 cell junction protein#PC00070;tight junction#PC00214 MONDO|Ensembl=ENSMODG00000013049.3|UniProtKB=F7G154 F7G154 IL22RA1 PTHR20859:SF53 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-22 RECEPTOR SUBUNIT ALPHA-1 transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to cytokine#GO:0034097;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002723.4|UniProtKB=F6Z7K3 F6Z7K3 TRAF5 PTHR10131:SF83 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 5 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;signal transduction#GO:0007165 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000012756.4|UniProtKB=F6SJK0 F6SJK0 MED1 PTHR12881:SF16 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 transcription coregulator activity#GO:0003712;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297;binding#GO:0005488;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to chemical stimulus#GO:0070887;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to hormone#GO:0009725;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000016827.4|UniProtKB=A0A5F8H347 A0A5F8H347 TCFL5 PTHR15402:SF2 TRANSCRIPTION FACTOR-LIKE 5 PROTEIN TRANSCRIPTION FACTOR LIKE 5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000003423.4|UniProtKB=F7GKK4 F7GKK4 FASN PTHR43775:SF7 FATTY ACID SYNTHASE FATTY ACID SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000045980.1|UniProtKB=A0A5F8G4G3 A0A5F8G4G3 CCL28 PTHR12015:SF205 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 28 cytokine#PC00083 MONDO|Ensembl=ENSMODG00000005045.3|UniProtKB=F7GA11 F7GA11 LOC100618250 PTHR24377:SF217 IP01015P-RELATED ZINC FINGER PROTEIN 286A-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000044769.1|UniProtKB=A0A5F8HAW3 A0A5F8HAW3 LOC100022580 PTHR26450:SF104 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017097.4|UniProtKB=F7DQF4 F7DQF4 PTHR24072:SF120 RHO FAMILY GTPASE RHO-RELATED BTB DOMAIN-CONTAINING PROTEIN 1 nucleoside phosphate binding#GO:1901265;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111 regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;actin filament organization#GO:0007015;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;establishment or maintenance of cell polarity#GO:0007163;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of developmental process#GO:0050793 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000004138.5|UniProtKB=A0A5F8GZZ9 A0A5F8GZZ9 FMNL2 PTHR45857:SF5 FORMIN-LIKE PROTEIN FORMIN-LIKE PROTEIN 2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 cellular process#GO:0009987;cell motility#GO:0048870;cell migration#GO:0016477 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000016607.3|UniProtKB=A0A5F8HH96 A0A5F8HH96 SMC1A PTHR18937:SF170 STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 1A nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000005461.5|UniProtKB=F7CGI3 F7CGI3 LZTS3 PTHR19354:SF6 ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED ZIPPER PUTATIVE TUMOR SUPPRESSOR 3-RELATED regulation of cell projection organization#GO:0031344;regulation of dendritic spine morphogenesis#GO:0061001;regulation of synapse organization#GO:0050807;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;regulation of neuron projection development#GO:0010975;regulation of biological process#GO:0050789;regulation of postsynapse organization#GO:0099175;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of developmental process#GO:0050793 cell junction#GO:0030054;dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;dendritic spine#GO:0043197;neuron projection#GO:0043005;postsynapse#GO:0098794 MONDO|Ensembl=ENSMODG00000040085.1|UniProtKB=A0A5F8H2E4 A0A5F8H2E4 PTHR11769:SF37 HYALURONIDASE HYALURONIDASE macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;glycosaminoglycan catabolic process#GO:0006027;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;glycosaminoglycan metabolic process#GO:0030203;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000005713.3|UniProtKB=F6U482 F6U482 LOC100027122 PTHR26452:SF806 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A16 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012017.4|UniProtKB=F7AM83 F7AM83 PIK3R4 PTHR17583:SF0 PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 intracellular protein transport#GO:0006886;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;metabolic process#GO:0008152;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;pexophagy#GO:0000425;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;establishment of protein localization#GO:0045184;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;vesicle-mediated transport#GO:0016192;protein localization to vacuole#GO:0072665;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;localization#GO:0051179;late endosome to vacuole transport#GO:0045324;protein localization to organelle#GO:0033365;protein targeting#GO:0006605;catabolic process#GO:0009056;establishment of protein localization to vacuole#GO:0072666 extrinsic component of membrane#GO:0019898;transferase complex#GO:1990234;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex, class III#GO:0035032;endosome#GO:0005768;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;organelle membrane contact site#GO:0044232 protein-binding activity modulator#PC00095;kinase modulator#PC00140 MONDO|Ensembl=ENSMODG00000024436.3|UniProtKB=F7DK59 F7DK59 CARMIL3 PTHR24112:SF43 LEUCINE-RICH REPEAT, ISOFORM F-RELATED CAPPING PROTEIN, ARP2_3 AND MYOSIN-I LINKER PROTEIN 3 cellular process#GO:0009987;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell migration#GO:0016477;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000000522.4|UniProtKB=F6Y5D0 F6Y5D0 SLC10A7 PTHR18640:SF5 SOLUTE CARRIER FAMILY 10 MEMBER 7 SODIUM_BILE ACID COTRANSPORTER 7 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000042624.1|UniProtKB=A0A5F8G9H3 A0A5F8G9H3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016106.4|UniProtKB=F7EB05 F7EB05 MEIOB PTHR21166:SF2 CELL DIVISION CONTROL PROTEIN 24 OB DOMAIN-CONTAINING PROTEIN-RELATED MEIOSIS-SPECIFIC WITH OB DOMAIN-CONTAINING PROTEIN 3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;hydrolase activity#GO:0016787;exonuclease activity#GO:0004527 homologous recombination#GO:0035825;reproductive process#GO:0022414;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;organelle fission#GO:0048285;sexual reproduction#GO:0019953;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;nucleobase-containing compound metabolic process#GO:0006139;resolution of meiotic recombination intermediates#GO:0000712;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA repair#GO:0006281;response to stimulus#GO:0050896;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000025062.1|UniProtKB=F7BN35 F7BN35 RNF152 PTHR25464:SF1 TRIPARTITE MOTIF-CONTAINING PROTEIN 2-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF152 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;response to stimulus#GO:0050896;negative regulation of TORC1 signaling#GO:1904262;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198 lysosomal membrane#GO:0005765;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000014130.4|UniProtKB=F6XK25 F6XK25 ZBTB16 PTHR24393:SF60 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 16 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002475.4|UniProtKB=F7BW75 F7BW75 NFIA PTHR11492:SF6 NUCLEAR FACTOR I NUCLEAR FACTOR 1 A-TYPE DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000021093.4|UniProtKB=A0A5F8GC14 A0A5F8GC14 MAOA PTHR43563:SF11 AMINE OXIDASE AMINE OXIDASE [FLAVIN-CONTAINING] A oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 serotonin metabolic process#GO:0042428;metabolic process#GO:0008152;amine catabolic process#GO:0009310;catabolic process#GO:0009056;biogenic amine metabolic process#GO:0006576;amine metabolic process#GO:0009308;phenol-containing compound metabolic process#GO:0018958;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;oxidase#PC00175 5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401;Dopamine receptor mediated signaling pathway#P05912>MAO#P05963;Adrenaline and noradrenaline biosynthesis#P00001>MAO#P00067 MONDO|Ensembl=ENSMODG00000045926.1|UniProtKB=F6Q355 F6Q355 LOC100024663 PTHR26450:SF151 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52B2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007577.4|UniProtKB=F7CPV6 F7CPV6 PTHR24242:SF256 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000023686.2|UniProtKB=F6SJE4 F6SJE4 PTHR11690:SF132 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED EPITHELIAL SODIUM CHANNEL SUBUNIT DELTA ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000017771.4|UniProtKB=A0A5F8G687 A0A5F8G687 ABCC9 PTHR24223:SF173 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000025460.2|UniProtKB=F6RK43 F6RK43 PTHR23268:SF101 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 9 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000015308.4|UniProtKB=F6XZ48 F6XZ48 RAP2C PTHR24070:SF200 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-2C hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;regulation of locomotion#GO:0040012;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906 MONDO|Ensembl=ENSMODG00000049690.1|UniProtKB=A0A5F8H8Z7 A0A5F8H8Z7 LOC100027959 PTHR26452:SF310 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000046495.1|UniProtKB=A0A5F8GLK4 A0A5F8GLK4 PTHR23430:SF59 HISTONE H2A HISTONE H2A structural molecule activity#GO:0005198 heterochromatin organization#GO:0070828;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000002823.2|UniProtKB=F6YAM8 F6YAM8 PRMT6 PTHR11006:SF73 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 6 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;histone modifying activity#GO:0140993;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000015247.4|UniProtKB=A0A5F8GQS2 A0A5F8GQS2 PTHR43340:SF6 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;cation binding#GO:0043169;magnesium ion binding#GO:0000287;metal ion binding#GO:0046872;pentosyltransferase activity#GO:0016763;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;IMP metabolic process#GO:0046040;primary metabolic process#GO:0044238;nucleobase metabolic process#GO:0009112;nucleoside phosphate biosynthetic process#GO:1901293;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247;Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804;Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245 MONDO|Ensembl=ENSMODG00000010839.4|UniProtKB=F7BDE2 F7BDE2 LOC100022164 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;glutathione transferase activity#GO:0004364;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491 glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000028700.2|UniProtKB=K7E4C5 K7E4C5 LOC103106146 PTHR24256:SF574 TRYPTASE-RELATED INACTIVE SERINE PROTEASE 39-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000018237.4|UniProtKB=F6PG65 F6PG65 LRP6 PTHR24270:SF51 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN binding#GO:0005488;protein binding#GO:0005515 developmental process#GO:0032502;transport#GO:0006810;multicellular organism development#GO:0007275;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;central nervous system development#GO:0007417;endocytosis#GO:0006897 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 apolipoprotein#PC00052;transfer/carrier protein#PC00219 Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112;Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Wnt signaling pathway#P00057>LRP5/6#P01431 MONDO|Ensembl=ENSMODG00000017168.3|UniProtKB=F6QD61 F6QD61 PTHR16019:SF6 SYNAPSE-ASSOCIATED PROTEIN SYNAPSE-ASSOCIATED PROTEIN 1 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;TORC2 signaling#GO:0038203;regulation of developmental process#GO:0050793;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of fat cell differentiation#GO:0045600;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007;TOR signaling#GO:0031929;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597 organelle#GO:0043226;endomembrane system#GO:0012505;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000002906.4|UniProtKB=F6PNF9 F6PNF9 KIAA0232 PTHR17611:SF3 DNA SEGMENT, CHR 5, ERATO DOI 579, EXPRESSED KIAA0232 HOMOLOG MONDO|Ensembl=ENSMODG00000024803.2|UniProtKB=F7FAT9 F7FAT9 PTHR12701:SF15 BCR-ASSOCIATED PROTEIN, BAP B-CELL RECEPTOR-ASSOCIATED PROTEIN 31 protein carrier activity#GO:0140597;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104 transport#GO:0006810;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;regulation of catabolic process#GO:0009894;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;response to endoplasmic reticulum stress#GO:0034976;localization#GO:0051179;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;primary metabolic process#GO:0044238;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;establishment of protein localization#GO:0045184;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;protein transport#GO:0015031;regulation of biological process#GO:0050789;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000020387.4|UniProtKB=F7C073 F7C073 CNOT2 PTHR23326:SF35 CCR4 NOT-RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2 negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070 CCR4-NOT complex#GO:0030014;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000044792.1|UniProtKB=A0A5F8G2N8 A0A5F8G2N8 THAP7 PTHR47502:SF1 THAP DOMAIN-CONTAINING PROTEIN 7 THAP DOMAIN-CONTAINING PROTEIN 7 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000042298.1|UniProtKB=A0A5F8H0K8 A0A5F8H0K8 VN2R619 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000047170.1|UniProtKB=F7EI19 F7EI19 LOC100024128 PTHR48018:SF166 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017578.4|UniProtKB=F7B5S9 F7B5S9 MED23 PTHR12691:SF10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000006993.5|UniProtKB=A0A5F8HI05 A0A5F8HI05 TCF20 PTHR14955:SF7 RETINOIC ACID INDUCED 1/TRANSCRIPTION FACTOR 20 TRANSCRIPTION FACTOR 20 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000020938.5|UniProtKB=H9H8Z6 H9H8Z6 PTHR45616:SF32 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 5 structural molecule activity#GO:0005198 developmental process#GO:0032502;epidermis development#GO:0008544;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular process#GO:0009987;organelle organization#GO:0006996;skin development#GO:0043588;cytoskeleton organization#GO:0007010;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;cellular component organization#GO:0016043;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104 supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000015527.3|UniProtKB=F6VI36 F6VI36 SPNS1 PTHR23505:SF13 SPINSTER PROTEIN SPINSTER HOMOLOG 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;carbohydrate derivative transport#GO:1901264;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000007077.4|UniProtKB=F6WPM0 F6WPM0 TM6SF2 PTHR14568:SF9 TRANSMEMBRANE SUPERFAMILY 6 MEMBER 1/2 TRANSMEMBRANE 6 SUPERFAMILY MEMBER 2 chemical homeostasis#GO:0048878;regulation of lipid metabolic process#GO:0019216;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;lipid homeostasis#GO:0055088;regulation of metabolic process#GO:0019222;homeostatic process#GO:0042592;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 MONDO|Ensembl=ENSMODG00000006585.4|UniProtKB=A0A5F8GAZ0 A0A5F8GAZ0 PSPH PTHR43344:SF2 PHOSPHOSERINE PHOSPHATASE PHOSPHOSERINE PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cation binding#GO:0043169;magnesium ion binding#GO:0000287;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 Serine glycine biosynthesis#P02776>Phosphoserine phosphatase#P03159 MONDO|Ensembl=ENSMODG00000020369.3|UniProtKB=F7FJP0 F7FJP0 LRRC10B PTHR45752:SF31 LEUCINE-RICH REPEAT-CONTAINING LEUCINE RICH REPEAT CONTAINING 10B scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000009871.2|UniProtKB=A0A5F8GMQ4 A0A5F8GMQ4 PLEKHA3 PTHR22902:SF60 SESQUIPEDALIAN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 3 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000021169.4|UniProtKB=A0A5F8HA81 A0A5F8HA81 MATCAP2 PTHR31817:SF3 FAMILY NOT NAMED TYROSINE CARBOXYPEPTIDASE MATCAP2-RELATED MONDO|Ensembl=ENSMODG00000046100.1|UniProtKB=F6UJX8 F6UJX8 PTHR19367:SF18 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 18 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000009423.4|UniProtKB=F7BKS4 F7BKS4 PTHR18863:SF5 TSEC-2-RELATED TESTIS EXPRESSED GENE 21 MONDO|Ensembl=ENSMODG00000016292.4|UniProtKB=F7AU27 F7AU27 PTHR20920:SF4 RPE-SPONDIN SMB DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000021300.4|UniProtKB=F7G3T4 F7G3T4 NDUFB5 PTHR13178:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SGDH SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 5, MITOCHONDRIAL respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000039770.1|UniProtKB=A0A5F8GBG0 A0A5F8GBG0 TMEM255B PTHR33721:SF3 TRANSMEMBRANE PROTEIN 255B-LIKE TRANSMEMBRANE PROTEIN 255B MONDO|Ensembl=ENSMODG00000018395.4|UniProtKB=A0A5F8HGR7 A0A5F8HGR7 UBE3D PTHR31531:SF2 E3 UBIQUITIN-PROTEIN LIGASE E3D FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE E3D catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;cyclin binding#GO:0030332;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;ubiquitin-like protein transferase activity#GO:0019787 catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000025331.2|UniProtKB=F7AXX7 F7AXX7 LOC100010178 PTHR10797:SF79 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 7 hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;RNA nuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;CCR4-NOT complex#GO:0030014 RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000028042.2|UniProtKB=F6Q199 F6Q199 PTHR12173:SF9 GDNF SUBFAMILY OF TGF-BETA FAMILY ARTEMIN signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083 neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;generation of neurons#GO:0048699;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207;neurotrophic factor#PC00163 MONDO|Ensembl=ENSMODG00000012655.4|UniProtKB=F6VXL8 F6VXL8 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000007145.3|UniProtKB=F6RYJ6 F6RYJ6 UPK3A PTHR15446:SF17 UROPLAKIN III UROPLAKIN-3A transport#GO:0006810;nitrogen compound transport#GO:0071705;fluid transport#GO:0042044;establishment of localization#GO:0051234;water transport#GO:0006833;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000005168.4|UniProtKB=F7E7U6 F7E7U6 PTHR13140:SF369 MYOSIN UNCONVENTIONAL MYOSIN-VIIA isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544 cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin filament-based movement#GO:0030048;cellular process#GO:0009987;organelle organization#GO:0006996;system process#GO:0003008;actin filament organization#GO:0007015;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;sensory organ development#GO:0007423;actin cytoskeleton organization#GO:0030036;sensory perception of sound#GO:0007605;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;animal gross anatomical part developmental process#GO:0160108 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;actin cytoskeleton#GO:0015629 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000040708.1|UniProtKB=F6Q291 F6Q291 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000009906.3|UniProtKB=F6UUX0 F6UUX0 LOC100033060 PTHR24093:SF245 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 1 ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion homeostasis#GO:0055074;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cytosolic calcium ion concentration#GO:0051480 organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000004140.4|UniProtKB=F6UDS3 F6UDS3 UTP23 PTHR12416:SF3 RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RRNA-PROCESSING PROTEIN UTP23 HOMOLOG rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000010439.1|UniProtKB=F6YT06 F6YT06 NKX6-3 PTHR24340:SF20 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-6.3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000006351.3|UniProtKB=F6ZRM4 F6ZRM4 VSX1 PTHR24323:SF3 CEH-10 HOMEODOMAIN-CONTAINING HOMOLOG VISUAL SYSTEM HOMEOBOX 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000037358.1|UniProtKB=A0A5F8GDU3 A0A5F8GDU3 PTHR13723:SF281 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE PAPILIN hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;external encapsulating structure organization#GO:0045229;metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000020138.3|UniProtKB=F7D5Q1 F7D5Q1 VN2R616 PTHR24061:SF0 CALCIUM-SENSING RECEPTOR-RELATED EXTRACELLULAR CALCIUM-SENSING RECEPTOR-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000004595.3|UniProtKB=F6QIQ8 F6QIQ8 FOXRED1 PTHR13847:SF294 SARCOSINE DEHYDROGENASE-RELATED FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000019529.4|UniProtKB=F6UV45 F6UV45 MIER3 PTHR10865:SF22 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN MESODERM INDUCTION EARLY RESPONSE PROTEIN 3 histone deacetylase binding#GO:0042826;protein binding#GO:0005515;transcription corepressor activity#GO:0003714;binding#GO:0005488;transcription coregulator activity#GO:0003712;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110 negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000012145.4|UniProtKB=A0A5F8GLH9 A0A5F8GLH9 ADGRL1 PTHR12011:SF62 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR L1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000016330.4|UniProtKB=F7FKX2 F7FKX2 SLC26A3 PTHR11814:SF19 SULFATE TRANSPORTER CHLORIDE ANION EXCHANGER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;chloride transmembrane transporter activity#GO:0015108;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;active transmembrane transporter activity#GO:0022804;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075;carboxylic acid transmembrane transporter activity#GO:0046943 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000013957.4|UniProtKB=F6RSA1 F6RSA1 RBM42 PTHR47640:SF11 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED RNA-BINDING PROTEIN 42 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 MONDO|Ensembl=ENSMODG00000048521.1|UniProtKB=A0A5F8GK38 A0A5F8GK38 PTHR24028:SF133 CADHERIN-87A PROTOCADHERIN ALPHA-9 cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000003468.4|UniProtKB=F7DC44 F7DC44 TMF1 PTHR46515:SF1 TATA ELEMENT MODULATORY FACTOR TMF1 TATA ELEMENT MODULATORY FACTOR organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000017606.4|UniProtKB=F7AHR6 F7AHR6 LRRC74B PTHR24114:SF37 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 74B MONDO|Ensembl=ENSMODG00000017563.4|UniProtKB=A0A5F8G4V5 A0A5F8G4V5 SCFD1 PTHR11679:SF2 VESICLE PROTEIN SORTING-ASSOCIATED SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;syntaxin binding#GO:0019905;SNARE binding#GO:0000149;binding#GO:0005488 protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein transport#GO:0006886;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000025519.2|UniProtKB=F6VJ37 F6VJ37 PTHR11385:SF11 SERUM ALBUMIN-RELATED VITAMIN D-BINDING PROTEIN steroid binding#GO:0005496;lipid binding#GO:0008289;binding#GO:0005488;small molecule binding#GO:0036094 vitamin D metabolic process#GO:0042359;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;response to stimulus#GO:0050896;steroid metabolic process#GO:0008202;primary metabolic process#GO:0044238;response to nutrient levels#GO:0031667;cellular process#GO:0009987 transfer/carrier protein#PC00219 Vitamin D metabolism and pathway#P04396>DBP#P04600 MONDO|Ensembl=ENSMODG00000008210.4|UniProtKB=F6ZEH0 F6ZEH0 PTHR10117:SF6 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 2 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;alcohol binding#GO:0043178;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;binding#GO:0005488 inorganic ion homeostasis#GO:0098771;sexual reproduction#GO:0019953;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of cytosolic calcium ion concentration#GO:0051480;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;reproductive process#GO:0022414;fertilization#GO:0009566;homeostatic process#GO:0042592;metal ion transport#GO:0030001;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;single fertilization#GO:0007338;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 MONDO|Ensembl=ENSMODG00000010471.4|UniProtKB=F7ET26 F7ET26 PCDH1 PTHR24028:SF247 CADHERIN-87A PROTOCADHERIN-1 cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000007719.3|UniProtKB=F7EUT4 F7EUT4 ATOSB PTHR13199:SF12 GH03947P ATOS HOMOLOG PROTEIN B MONDO|Ensembl=ENSMODG00000000599.3|UniProtKB=F6TBF2 F6TBF2 LRRC14B PTHR14224:SF27 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 14B MONDO|Ensembl=ENSMODG00000020976.3|UniProtKB=F6S5U4 F6S5U4 PTHR46105:SF1 AGAP004733-PA TRANSCRIPTION REGULATOR PROTEIN BACH1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006953.4|UniProtKB=A0A5F8GXI9 A0A5F8GXI9 PTHR21603:SF17 ANTIGEN KI-67-LIKE PROTEIN PROLIFERATION MARKER PROTEIN KI-67 molecular condensate scaffold activity#GO:0140693;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 sexual reproduction#GO:0019953;cell cycle#GO:0007049;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;reproductive process#GO:0022414;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;regulation of mitotic nuclear division#GO:0007088;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of nuclear division#GO:0051783 intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000045587.1|UniProtKB=A0A5F8HBZ2 A0A5F8HBZ2 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008793.3|UniProtKB=A0A5F8H3F2 A0A5F8H3F2 DISC1 PTHR14332:SF3 DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;animal organ development#GO:0048513;neurogenesis#GO:0022008;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;brain development#GO:0007420;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;cell migration#GO:0016477;head development#GO:0060322;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell differentiation#GO:0030154;cell projection organization#GO:0030030;central nervous system development#GO:0007417;cell motility#GO:0048870 membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular membraneless organelle#GO:0043232;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794 MONDO|Ensembl=ENSMODG00000004556.3|UniProtKB=F6R5E1 F6R5E1 EDEM1 PTHR45679:SF5 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 1 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007 MONDO|Ensembl=ENSMODG00000018584.4|UniProtKB=A0A5F8GE10 A0A5F8GE10 COL19A1 PTHR24023:SF938 COLLAGEN ALPHA COLLAGEN ALPHA-1(XIX) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000015633.3|UniProtKB=F7FEN3 F7FEN3 VWC2L PTHR46252:SF2 BRORIN FAMILY MEMBER VON WILLEBRAND FACTOR C DOMAIN-CONTAINING PROTEIN 2-LIKE negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of BMP signaling pathway#GO:0030514;regulation of BMP signaling pathway#GO:0030510;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 signaling receptor complex#GO:0043235;extracellular region#GO:0005576;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000039597.1|UniProtKB=A0A5F8G9T5 A0A5F8G9T5 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000017861.3|UniProtKB=F6YIL8 F6YIL8 LOC100010706 PTHR19282:SF184 TETRASPANIN PERIPHERIN 2 LIKE-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019545.4|UniProtKB=A0A5F8GNK6 A0A5F8GNK6 RAD21L1 PTHR12585:SF19 SCC1 / RAD21 FAMILY MEMBER DOUBLE-STRAND-BREAK REPAIR PROTEIN RAD21-LIKE PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;sister chromatid cohesion#GO:0007062;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;response to stimulus#GO:0050896;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;organelle organization#GO:0006996;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cohesin complex#GO:0008278;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000008657.4|UniProtKB=F6PG98 F6PG98 MNAT1 PTHR12683:SF13 CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1 CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription initiation#GO:0006352;response to stimulus#GO:0050896;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;RNA metabolic process#GO:0016070;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transcription factor TFIIH holo complex#GO:0005675;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II, holoenzyme#GO:0016591;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000015028.4|UniProtKB=F7BXC7 F7BXC7 PTHR24376:SF245 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 585A C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000010556.4|UniProtKB=A0A5F8G1S8 A0A5F8G1S8 NCKAP1 PTHR12093:SF11 NCK-ASSOCIATED PROTEIN 1 NCK-ASSOCIATED PROTEIN 1 nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cell migration#GO:0016477;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;system development#GO:0048731;anatomical structure development#GO:0048856;cortical actin cytoskeleton organization#GO:0030866;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000025746.2|UniProtKB=F6T1T6 F6T1T6 PTHR46019:SF1 BPI FOLD-CONTAINING FAMILY B MEMBER 4-RELATED BPI FOLD-CONTAINING FAMILY B MEMBER 2 MONDO|Ensembl=ENSMODG00000012824.4|UniProtKB=A0A5F8GR43 A0A5F8GR43 PGAP3 PTHR13148:SF0 PER1-RELATED GPI-SPECIFIC PHOSPHOLIPASE A2-LIKE PGAP3 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;GPI anchored protein biosynthesis#GO:0180046;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000006829.4|UniProtKB=F6PG49 F6PG49 RNASEL PTHR24141:SF4 2-5A-DEPENDENT RIBONUCLEASE 2-5A-DEPENDENT RIBONUCLEASE nuclease activity#GO:0004518;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 gene expression#GO:0010467;response to other organism#GO:0051707;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;defense response#GO:0006952;response to external stimulus#GO:0009605;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;response to stimulus#GO:0050896;RNA biosynthetic process#GO:0032774;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to virus#GO:0009615;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000043113.1|UniProtKB=A0A5F8HGX3 A0A5F8HGX3 PTHR24249:SF271 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 6 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000012040.3|UniProtKB=H9H8Y7 H9H8Y7 PTHR24012:SF409 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 1 mRNA binding#GO:0003729;poly(A) binding#GO:0008143;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000042596.1|UniProtKB=A0A5F8GG17 A0A5F8GG17 PTHR45635:SF13 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE 3 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000041128.1|UniProtKB=A0A5F8HGG7 A0A5F8HGG7 LOC130453503 PTHR10500:SF7 BETA-MICROSEMINOPROTEIN MICROSEMINOPROTEIN BETA intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000024815.2|UniProtKB=F7AYF5 F7AYF5 BBIP1 PTHR28596:SF1 BBSOME-INTERACTING PROTEIN 1 BBSOME-INTERACTING PROTEIN 1 cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;protein localization to cilium#GO:0061512;organelle assembly#GO:0070925;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;protein localization to cell periphery#GO:1990778;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104 cilium#GO:0005929;cell projection membrane#GO:0031253;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cell periphery#GO:0071944;BBSome#GO:0034464;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;ciliary membrane#GO:0060170;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000006232.4|UniProtKB=F7FS52 F7FS52 ZFAND1 PTHR14677:SF37 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED AN1-TYPE ZINC FINGER PROTEIN 1 protein-containing complex disassembly#GO:0032984;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cellular component disassembly#GO:0022411;protein-RNA complex organization#GO:0071826;organelle disassembly#GO:1903008;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000019177.3|UniProtKB=A0A5F8G4F8 A0A5F8G4F8 MYO1D PTHR13140:SF417 MYOSIN UNCONVENTIONAL MYOSIN-ID macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based movement#GO:0030048;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;microvillus#GO:0005902;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000017235.4|UniProtKB=F6WHP4 F6WHP4 LOC100022811 PTHR46485:SF2 LIM DOMAIN KINASE 1 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000046888.1|UniProtKB=A0A5F8HC25 A0A5F8HC25 AIF1L PTHR10356:SF5 ALLOGRAFT INFLAMMATORY FACTOR-1 ALLOGRAFT INFLAMMATORY FACTOR 1-LIKE metal ion binding#GO:0046872;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;cell projection organization#GO:0030030;actin cytoskeleton organization#GO:0030036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;cell projection membrane#GO:0031253;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;leading edge membrane#GO:0031256;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;plasma membrane region#GO:0098590;supramolecular polymer#GO:0099081;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;ruffle#GO:0001726;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;ruffle membrane#GO:0032587;actin filament#GO:0005884 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000037031.1|UniProtKB=F6Z5E9 F6Z5E9 LOC100016509 PTHR48018:SF168 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000036730.1|UniProtKB=A0A5F8H9A9 A0A5F8H9A9 PTHR26454:SF77 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012517.4|UniProtKB=A0A5F8G9B2 A0A5F8G9B2 IL17RB PTHR15583:SF11 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 cell surface receptor signaling pathway#GO:0007166;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;cell communication#GO:0007154;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signaling#GO:0023052;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013074.2|UniProtKB=A0A5F8GD21 A0A5F8GD21 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000005619.4|UniProtKB=F7CZ61 F7CZ61 DAD1 PTHR10705:SF0 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000003275.4|UniProtKB=F7EGK9 F7EGK9 TSSK4 PTHR24343:SF345 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 4 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000009178.3|UniProtKB=F7AD23 F7AD23 PTHR10742:SF235 FLAVIN MONOAMINE OXIDASE AMINE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 oxidase#PC00175 MONDO|Ensembl=ENSMODG00000014291.4|UniProtKB=F6WKA0 F6WKA0 USP15 PTHR21646:SF28 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15 cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;RNA biosynthetic process#GO:0032774;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;DNA-templated transcription elongation#GO:0006354;regulation of protein stability#GO:0031647;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;chromatin organization#GO:0006325;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000014774.5|UniProtKB=A0A5F8H1L7 A0A5F8H1L7 ZNF385C PTHR23067:SF6 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385C nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000041452.1|UniProtKB=A0A5F8G5H0 A0A5F8G5H0 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000003796.4|UniProtKB=A0A5F8HHZ8 A0A5F8HHZ8 MYOC PTHR23192:SF33 OLFACTOMEDIN-RELATED MYOCILIN cell differentiation#GO:0030154;response to stimulus#GO:0050896;ossification#GO:0001503;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cellular developmental process#GO:0048869;developmental process#GO:0032502;osteoblast differentiation#GO:0001649 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;extracellular region#GO:0005576;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000018979.4|UniProtKB=A0A5F8G314 A0A5F8G314 DNPH1 PTHR15364:SF0 2'-DEOXYNUCLEOSIDE 5'-PHOSPHATE N-HYDROLASE 1 5-HYDROXYMETHYL-DUMP N-HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824 organophosphate catabolic process#GO:0046434;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;nucleoside monophosphate metabolic process#GO:0009123;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000024020.2|UniProtKB=A0A5F8H121 A0A5F8H121 PTHR13639:SF2 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000029568.2|UniProtKB=K7E1G0 K7E1G0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000005488.5|UniProtKB=F7BXZ6 F7BXZ6 PANX2 PTHR15759:SF7 PANNEXIN PANNEXIN-2 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267 biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;regulation of biological process#GO:0050789;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000011038.4|UniProtKB=A0A5F8GJZ2 A0A5F8GJZ2 EPB41 PTHR23280:SF12 4.1 G PROTEIN PROTEIN 4.1 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 Nicotine pharmacodynamics pathway#P06587>EPB41#P06607;Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 MONDO|Ensembl=ENSMODG00000020351.4|UniProtKB=A0A5F8HDT0 A0A5F8HDT0 NIPBL PTHR21704:SF19 NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED NIPPED-B-LIKE PROTEIN binding#GO:0005488;chromatin binding#GO:0003682 skeletal system development#GO:0001501;cellular response to stress#GO:0033554;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;central nervous system development#GO:0007417;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;double-strand break repair#GO:0006302;animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nervous system development#GO:0007399;embryo development#GO:0009790;head development#GO:0060322;heart development#GO:0007507;cellular process#GO:0009987;establishment of protein localization#GO:0045184;response to stress#GO:0006950;organelle organization#GO:0006996;system development#GO:0048731;sister chromatid cohesion#GO:0007062;anatomical structure development#GO:0048856;localization#GO:0051179;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;recombinational repair#GO:0000725;animal organ morphogenesis#GO:0009887;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;heart morphogenesis#GO:0003007;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;DNA damage response#GO:0006974;developmental process#GO:0032502;DNA repair#GO:0006281;tube development#GO:0035295;nucleobase-containing compound metabolic process#GO:0006139;multicellular organismal process#GO:0032501;brain development#GO:0007420;mitotic sister chromatid cohesion#GO:0007064;skeletal system morphogenesis#GO:0048705;replication-born double-strand break repair via sister chromatid exchange#GO:1990414 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000025260.1|UniProtKB=F7BD96 F7BD96 PTHR19424:SF3 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR-BINDING PROTEIN 1 cellular response to stress#GO:0033554;response to stimulus#GO:0050896;response to temperature stimulus#GO:0009266;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;heat acclimation#GO:0010286;response to heat#GO:0009408;cellular response to heat#GO:0034605;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000017670.3|UniProtKB=A0A5F8HL76 A0A5F8HL76 DUOXA1 PTHR31158:SF3 DUAL OXIDASE 2 DUAL OXIDASE MATURATION FACTOR 1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidase#PC00175;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000002145.4|UniProtKB=F7EM52 F7EM52 PTHR24356:SF136 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE_THREONINE-PROTEIN KINASE 2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;transferase activity#GO:0016740 organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell cycle#GO:0051726;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000005683.4|UniProtKB=A0A5F8GSJ1 A0A5F8GSJ1 PTHR28535:SF1 ZINC FINGER GRF-TYPE CONTAINING 1 5'-3' DNA HELICASE ZGRF1 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000046305.1|UniProtKB=A0A5F8HF50 A0A5F8HF50 LOC100024398 PTHR48018:SF10 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000042792.1|UniProtKB=A0A5F8H584 A0A5F8H584 LOC100028446 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000024981.2|UniProtKB=F6XNZ8 F6XNZ8 PIGC PTHR12982:SF0 PHOSPHATIDYLINOSITOL GLYCAN, CLASS C PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT C biosynthetic process#GO:0009058;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247 endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000002159.4|UniProtKB=F6YEW2 F6YEW2 YOD1 PTHR13312:SF0 HIV-INDUCED PROTEIN-7-LIKE PROTEASE UBIQUITIN THIOESTERASE OTU1 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to topologically incorrect protein#GO:0035967;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;response to unfolded protein#GO:0006986;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000017630.4|UniProtKB=F6ZSD8 F6ZSD8 SLC30A4 PTHR11562:SF27 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A4-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transport#GO:0006810;response to metal ion#GO:0010038;response to chemical#GO:0042221;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;response to stimulus#GO:0050896;metal ion transport#GO:0030001 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000041395.1|UniProtKB=H9H9H2 H9H9H2 PTHR24390:SF250 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 763 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000013577.4|UniProtKB=F7BHV6 F7BHV6 KRT23 PTHR23239:SF44 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 23 structural molecule activity#GO:0005198 morphogenesis of an epithelium#GO:0002009;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;cytoskeleton organization#GO:0007010;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000028900.2|UniProtKB=A0A5F8H8M5 A0A5F8H8M5 MAP7D3 PTHR15073:SF5 MICROTUBULE-ASSOCIATED PROTEIN MAP7 DOMAIN-CONTAINING PROTEIN 3 regulation of cellular process#GO:0050794;regulation of microtubule-based movement#GO:0060632;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of biological process#GO:0050789;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of microtubule-based process#GO:0032886;microtubule bundle formation#GO:0001578 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000027860.2|UniProtKB=K7E1M4 K7E1M4 C2CD4D PTHR46291:SF1 C2 DOMAIN-CONTAINING PROTEIN C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4D MONDO|Ensembl=ENSMODG00000015368.3|UniProtKB=F6WHK7 F6WHK7 SPAM1 PTHR11769:SF20 HYALURONIDASE HYALURONIDASE PH-20 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosaminoglycan metabolic process#GO:0030203;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;glycosaminoglycan catabolic process#GO:0006027;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152 acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000049015.1|UniProtKB=F6QLC5 F6QLC5 PTHR48001:SF39 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000022950.3|UniProtKB=F6PIE2 F6PIE2 DOC2A PTHR45729:SF1 RABPHILIN, ISOFORM A DOUBLE C2-LIKE DOMAIN-CONTAINING PROTEIN ALPHA regulation of secretion#GO:0051046;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;regulation of exocytosis#GO:0017157;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;positive regulation of cellular process#GO:0048522;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;positive regulation of secretion#GO:0051047;positive regulation of cellular component organization#GO:0051130;regulation of cellular component organization#GO:0051128;export from cell#GO:0140352;signaling#GO:0023052;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;vesicle-mediated transport in synapse#GO:0099003;regulation of localization#GO:0032879;exocytosis#GO:0006887;positive regulation of vesicle fusion#GO:0031340;regulation of transport#GO:0051049;regulated exocytosis#GO:0045055;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987 exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;presynapse#GO:0098793;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000011891.4|UniProtKB=F7EHD0 F7EHD0 CHRNB4 PTHR18945:SF385 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-4 monoatomic cation transmembrane transporter activity#GO:0008324;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094 synaptic transmission, cholinergic#GO:0007271;multicellular organismal process#GO:0032501;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;establishment of localization#GO:0051234;system process#GO:0003008;transport#GO:0006810;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;response to nitrogen compound#GO:1901698;trans-synaptic signaling#GO:0099537;response to chemical#GO:0042221;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;renal system process#GO:0003014;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;neuromuscular synaptic transmission#GO:0007274;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700 transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotine pharmacodynamics pathway#P06587>CHRNB4#P06610;Nicotinic acetylcholine receptor signaling pathway#P00044>beta#P01095 MONDO|Ensembl=ENSMODG00000007645.2|UniProtKB=A0A5F8G6X6 A0A5F8G6X6 LOC100026672 PTHR11851:SF226 METALLOPROTEASE CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL protein localization to mitochondrion#GO:0070585;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365 membrane protein complex#GO:0098796;organelle lumen#GO:0043233;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;mitochondrial matrix#GO:0005759;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;peptidase complex#GO:1905368;cytoplasm#GO:0005737;endopeptidase complex#GO:1905369;transporter complex#GO:1990351;respiratory chain complex III#GO:0045275 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000041517.1|UniProtKB=A0A5F8GSD4 A0A5F8GSD4 EPHX3 PTHR43329:SF10 EPOXIDE HYDROLASE EPOXIDE HYDROLASE 3 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ether hydrolase activity#GO:0016803 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000018233.4|UniProtKB=F6PGB5 F6PGB5 GTF2E1 PTHR13097:SF8 TRANSCRIPTION INITIATION FACTOR IIE, ALPHA SUBUNIT GENERAL TRANSCRIPTION FACTOR IIE SUBUNIT 1 DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIEalpha#P00669;General transcription regulation#P00023>TFIIE#P00666;Transcription regulation by bZIP transcription factor#P00055>TFIIEalpha#P01398;Transcription regulation by bZIP transcription factor#P00055>TFIIE#P01395 MONDO|Ensembl=ENSMODG00000006478.4|UniProtKB=F7FG73 F7FG73 PTHR10102:SF28 DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;sequence-specific double-stranded DNA binding#GO:1990837;catalytic activity, acting on RNA#GO:0140098;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mitochondrial transcription#GO:0006390;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;RNA polymerase complex#GO:0030880;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000005263.4|UniProtKB=F7GGQ9 F7GGQ9 ALKBH1 PTHR16557:SF12 ALKYLATED DNA REPAIR PROTEIN ALKB-RELATED NUCLEIC ACID DIOXYGENASE ALKBH1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;ion binding#GO:0043167;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;dioxygenase activity#GO:0051213;cation binding#GO:0043169;ferrous iron binding#GO:0008198;catalytic activity, acting on DNA#GO:0140097;demethylase activity#GO:0032451;iron ion binding#GO:0005506;catalytic activity, acting on RNA#GO:0140098;binding#GO:0005488;metal ion binding#GO:0046872 macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;metabolic process#GO:0008152;RNA modification#GO:0009451;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000029758.2|UniProtKB=F6RJJ9 F6RJJ9 PTHR23268:SF127 T-CELL RECEPTOR BETA CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000001978.4|UniProtKB=F6RII3 F6RII3 APPL2 PTHR46415:SF1 ADAPTOR PROTEIN, PHOSPHOTYROSINE INTERACTION, PH DOMAIN AND LEUCINE ZIPPER-CONTAINING 2 DCC-INTERACTING PROTEIN 13-BETA regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052 intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000009146.4|UniProtKB=F7B0U4 F7B0U4 EFEMP2 PTHR24034:SF96 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 2 cellular component assembly#GO:0022607;extracellular matrix assembly#GO:0085029;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000042610.1|UniProtKB=A0A5F8GD66 A0A5F8GD66 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013998.4|UniProtKB=F6SY02 F6SY02 IGFLR1 PTHR14657:SF2 IGF-LIKE FAMILY RECEPTOR 1 IGF-LIKE FAMILY RECEPTOR 1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000036504.1|UniProtKB=A0A5F8HGJ2 A0A5F8HGJ2 PTHR23239:SF96 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 9 structural molecule activity#GO:0005198 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular process#GO:0009987;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;morphogenesis of an epithelium#GO:0002009 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000007790.4|UniProtKB=F7A8J4 F7A8J4 DENND5A PTHR46070:SF2 PINSTRIPE, ISOFORM A DENN DOMAIN-CONTAINING PROTEIN 5A nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515 retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;Golgi apparatus subcompartment#GO:0098791 MONDO|Ensembl=ENSMODG00000002197.4|UniProtKB=F7GDW9 F7GDW9 CFAP276 PTHR48619:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 276 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 276 MONDO|Ensembl=ENSMODG00000048583.1|UniProtKB=K7DYZ1 K7DYZ1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003963.3|UniProtKB=A0A5F8GMB5 A0A5F8GMB5 HOGA1 PTHR12128:SF74 DIHYDRODIPICOLINATE SYNTHASE 4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;aldehyde catabolic process#GO:0046185;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;glyoxylate metabolic process#GO:0046487;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 lyase#PC00144 MONDO|Ensembl=ENSMODG00000019583.4|UniProtKB=F6QM90 F6QM90 ISG20 PTHR12801:SF59 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED INTERFERON-STIMULATED GENE 20 KDA PROTEIN catalytic activity#GO:0003824;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 response to other organism#GO:0051707;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;defense response#GO:0006952;response to external stimulus#GO:0009605;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;response to external biotic stimulus#GO:0043207;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to virus#GO:0009615;gene expression#GO:0010467;RNA processing#GO:0006396;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;DNA catabolic process#GO:0006308;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 exoribonuclease#PC00099;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000002158.5|UniProtKB=F6YEV5 F6YEV5 TOMM70 PTHR46208:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000037895.1|UniProtKB=F7AI23 F7AI23 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000049228.1|UniProtKB=A0A5F8HEB5 A0A5F8HEB5 LOC100618014 PTHR48002:SF74 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007206.3|UniProtKB=A0A5F8H3T8 A0A5F8H3T8 PTHR35672:SF1 C-U-EDITING ENZYME APOBEC-4-RELATED DEAMINASE APOBEC-4-RELATED MONDO|Ensembl=ENSMODG00000007149.5|UniProtKB=F6RYB4 F6RYB4 MAP3K9 PTHR44329:SF35 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 9 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;MAP kinase kinase kinase activity#GO:0004709 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834 MONDO|Ensembl=ENSMODG00000028389.2|UniProtKB=K7E2H0 K7E2H0 RPS8 PTHR10394:SF3 40S RIBOSOMAL PROTEIN S8 SMALL RIBOSOMAL SUBUNIT PROTEIN ES8 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000007644.3|UniProtKB=F7AYC2 F7AYC2 DECR1 PTHR43658:SF14 SHORT-CHAIN DEHYDROGENASE/REDUCTASE 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING], MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 lipid modification#GO:0030258;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000038175.1|UniProtKB=A0A5F8G6M0 A0A5F8G6M0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016946.4|UniProtKB=F6V6C6 F6V6C6 LMNA PTHR45721:SF5 LAMIN DM0-RELATED PRELAMIN-A_C structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 biological regulation#GO:0065007;membrane organization#GO:0061024;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;protein localization to nucleus#GO:0034504;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;regulation of gene expression#GO:0010468;nuclear envelope organization#GO:0006998;intracellular protein localization#GO:0008104;nucleus organization#GO:0006997;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;nuclear migration#GO:0007097;localization#GO:0051179;localization within membrane#GO:0051668;organelle localization#GO:0051640;heterochromatin organization#GO:0070828;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;cellular localization#GO:0051641 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear lumen#GO:0031981;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 FAS signaling pathway#P00020>Nuclear Lamin#P00616 MONDO|Ensembl=ENSMODG00000041489.1|UniProtKB=A0A5F8GWT2 A0A5F8GWT2 PTHR23268:SF14 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 12-3-RELATED regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000005569.4|UniProtKB=F7F3L8 F7F3L8 SLC25A32 PTHR45683:SF18 MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 32 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000017492.4|UniProtKB=F7FEP0 F7FEP0 PTHR11430:SF124 LIPOCALIN LIPOCALIN 1-LIKE PROTEIN 1-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000000198.4|UniProtKB=F6TFF9 F6TFF9 DLL4 PTHR24044:SF320 NOTCH LIGAND FAMILY MEMBER DELTA-LIKE PROTEIN 4 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;negative regulation of Notch signaling pathway#GO:0045746;Notch signaling pathway#GO:0007219;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Angiogenesis#P00005>Delta/Serrate#P00226;Notch signaling pathway#P00045>Delta#P01116 MONDO|Ensembl=ENSMODG00000041206.1|UniProtKB=A0A5F8GGP6 A0A5F8GGP6 PTHR13025:SF5 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN-CONTAINING PROTEIN D1 molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000047066.1|UniProtKB=A0A5F8GV35 A0A5F8GV35 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005741.3|UniProtKB=F6QE84 F6QE84 DENND6B PTHR13677:SF2 LD41638P PROTEIN DENND6B enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 recycling endosome#GO:0055037;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000037924.1|UniProtKB=F6Q1P8 F6Q1P8 OR52N1 PTHR26450:SF145 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52N1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014505.3|UniProtKB=A0A5F8HFP4 A0A5F8HFP4 GNPNAT1 PTHR13355:SF11 GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE glucosamine 6-phosphate N-acetyltransferase activity#GO:0004343;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080 metabolite interconversion enzyme#PC00262;acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000007695.4|UniProtKB=A0A5F8HHX5 A0A5F8HHX5 GABRG2 PTHR18945:SF498 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;ligand-gated monoatomic ion channel activity#GO:0015276 establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;localization#GO:0051179;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;anatomical structure development#GO:0048856;system development#GO:0048731;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;chloride transport#GO:0006821;cellular component assembly#GO:0022607;monoatomic anion transmembrane transport#GO:0098656;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;cellular process#GO:0009987;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;animal gross anatomical part developmental process#GO:0160108;synapse assembly#GO:0007416;signaling#GO:0023052;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 cell junction#GO:0030054;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell projection membrane#GO:0031253;dendrite#GO:0030425;dendritic tree#GO:0097447;leading edge membrane#GO:0031256;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000021513.4|UniProtKB=F7FSG2 F7FSG2 KCTD1 PTHR14499:SF65 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD1 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000015506.4|UniProtKB=F6VZL0 F6VZL0 AAMP PTHR19857:SF27 MITOCHONDRIAL DIVISION PROTEIN 1-RELATED ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cellular process#GO:0009987;cell adhesion#GO:0007155;cell migration#GO:0016477;cell motility#GO:0048870 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000047620.1|UniProtKB=A0A5F8G7I1 A0A5F8G7I1 PTHR16932:SF2 INTERFERON ALPHA-INDUCIBLE PROTEIN 27 INTERFERON ALPHA-INDUCIBLE PROTEIN 27, MITOCHONDRIAL intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;programmed cell death#GO:0012501;cell death#GO:0008219;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740 MONDO|Ensembl=ENSMODG00000028659.2|UniProtKB=F6PI12 F6PI12 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008441.4|UniProtKB=F7AKC0 F7AKC0 PACS1 PTHR13280:SF16 PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN 1 intracellular protein localization#GO:0008104;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;protein localization to Golgi apparatus#GO:0034067;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;protein localization to plasma membrane#GO:0072659 MONDO|Ensembl=ENSMODG00000027577.2|UniProtKB=K7E1J9 K7E1J9 LOC103096394 PTHR23120:SF46 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT LIKE REPEAT FAMILY MEMBER 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000044220.1|UniProtKB=A0A5F8HA07 A0A5F8HA07 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000010801.3|UniProtKB=A0A5F8GXF5 A0A5F8GXF5 MFN2 PTHR10465:SF1 TRANSMEMBRANE GTPASE FZO1 MITOFUSIN-2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 mitochondrion organization#GO:0007005;organelle fusion#GO:0048284;cellular process#GO:0009987;cellular component organization#GO:0016043;mitochondrial fusion#GO:0008053;organelle organization#GO:0006996;mitochondrion localization#GO:0051646;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;organelle localization#GO:0051640 mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000002667.4|UniProtKB=F7DHV0 F7DHV0 FOLH1 PTHR10404:SF36 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE GLUTAMATE CARBOXYPEPTIDASE 2-RELATED catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000012022.4|UniProtKB=F7FMA5 F7FMA5 FDFT1 PTHR11626:SF8 FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE SQUALENE SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;phospholipid metabolic process#GO:0006644;secondary alcohol metabolic process#GO:1902652;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;organophosphate metabolic process#GO:0019637;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;secondary alcohol biosynthetic process#GO:1902653;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220 Cholesterol biosynthesis#P00014>Farnesyl-diphosphate farnesyltransferase#P00499 MONDO|Ensembl=ENSMODG00000015696.4|UniProtKB=F7E0Q7 F7E0Q7 ALDOA PTHR11627:SF1 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE A catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832;fructose-bisphosphate aldolase activity#GO:0004332 cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 lyase#PC00144;aldolase#PC00044 Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959;Glycolysis#P00024>Aldolase#P00679 MONDO|Ensembl=ENSMODG00000051394.1|UniProtKB=F7FQI2 F7FQI2 PTHR24404:SF96 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000014410.4|UniProtKB=A0A5F8GNA9 A0A5F8GNA9 BAAT PTHR10824:SF1 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COENZYME A AMINO ACID N-ACYLTRANSFERASE 1-RELATED catalytic activity#GO:0003824;deacylase activity#GO:0160215;transferase activity#GO:0016740;hydrolase activity, acting on ester bonds#GO:0016788;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;acyl-CoA hydrolase activity#GO:0016289;fatty acyl-CoA hydrolase activity#GO:0047617;thiolester hydrolase activity#GO:0016790;hydrolase activity#GO:0016787 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;steroid metabolic process#GO:0008202;oxoacid metabolic process#GO:0043436;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;cytosol#GO:0005829;peroxisome#GO:0005777 esterase#PC00097 MONDO|Ensembl=ENSMODG00000046853.1|UniProtKB=A0A5F8H6G2 A0A5F8H6G2 PTHR24377:SF1028 IP01015P-RELATED ZINC FINGER PROTEIN 84 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025626.3|UniProtKB=F6XWT5 F6XWT5 DEPTOR PTHR22829:SF18 DEP DOMAIN PROTEIN DEP DOMAIN-CONTAINING MTOR-INTERACTING PROTEIN protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase inhibitor activity#GO:0019210;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme inhibitor activity#GO:0004857;enzyme activator activity#GO:0008047;molecular function inhibitor activity#GO:0140678;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;negative regulation of TORC1 signaling#GO:1904262;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signaling#GO:0023057 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000045146.1|UniProtKB=A0A5F8H816 A0A5F8H816 PTHR14292:SF2 INTERLEUKIN-18-BINDING PROTEIN INTERLEUKIN-18-BINDING PROTEIN binding#GO:0005488;cytokine binding#GO:0019955;protein binding#GO:0005515 response to stimulus#GO:0050896;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000002744.4|UniProtKB=A0A5F8H6R9 A0A5F8H6R9 MYEF2 PTHR23003:SF15 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN MYELIN EXPRESSION FACTOR 2 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nuclear mRNA surveillance#GO:0071028;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;rRNA processing#GO:0006364 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000007201.4|UniProtKB=F6X8Y4 F6X8Y4 NDUFA13 PTHR12966:SF0 NADH DEHYDROGENASE UBIQUINONE 1 ALPHA SUBCOMPLEX SUBUNIT 13 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 13 respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000004873.4|UniProtKB=F6T8B5 F6T8B5 BARX2 PTHR24330:SF7 HOMEOBOX PROTEIN BARH-LIKE HOMEOBOX PROTEIN BARH-LIKE 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000028393.2|UniProtKB=K7E534 K7E534 MMGT1 PTHR21181:SF7 ER membrane protein complex subunit 5-related ER MEMBRANE PROTEIN COMPLEX SUBUNIT 5 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977 intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 MONDO|Ensembl=ENSMODG00000010909.4|UniProtKB=F7F5F3 F7F5F3 CIAO2A PTHR12377:SF2 CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2A metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000049558.1|UniProtKB=A0A5F8H148 A0A5F8H148 LOC100022823 PTHR26450:SF123 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52H1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023685.1|UniProtKB=F6SJI0 F6SJI0 PTHR11716:SF6 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2 HOMOLOG OTOCONIN-22 A2-type glycerophospholipase activity#GO:0004623;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;metal ion binding#GO:0046872;lipid binding#GO:0008289;binding#GO:0005488;calcium ion binding#GO:0005509;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;cation binding#GO:0043169;small molecule binding#GO:0036094;lipase activity#GO:0016298;ion binding#GO:0043167;carboxylic ester hydrolase activity#GO:0052689 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phosphatidylglycerol metabolic process#GO:0046471;phosphatidylcholine metabolic process#GO:0046470;cellular process#GO:0009987;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000020876.4|UniProtKB=H9H7P3 H9H7P3 IARS1 PTHR42780:SF1 SOLEUCYL-TRNA SYNTHETASE ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;cytosol#GO:0005829 aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000005266.4|UniProtKB=F7CJB9 F7CJB9 PTHR11920:SF477 GUANYLYL CYCLASE GUANYLATE CYCLASE D molecular transducer activity#GO:0060089;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383;peptide receptor activity#GO:0001653 nucleoside phosphate biosynthetic process#GO:1901293;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;cyclic nucleotide metabolic process#GO:0009187;multicellular organismal process#GO:0032501;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;detection of stimulus#GO:0051606;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;sensory perception#GO:0007600;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;response to chemical#GO:0042221;ribose phosphate biosynthetic process#GO:0046390;detection of stimulus involved in sensory perception#GO:0050906;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;detection of chemical stimulus involved in sensory perception#GO:0050907;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nervous system process#GO:0050877;cyclic nucleotide biosynthetic process#GO:0009190;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;detection of chemical stimulus#GO:0009593;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730 guanylate cyclase#PC00114;lyase#PC00144 MONDO|Ensembl=ENSMODG00000014494.4|UniProtKB=A0A5F8GBP1 A0A5F8GBP1 DDX19B PTHR47958:SF93 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX19A RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;macromolecular conformation isomerase activity#GO:0120543 localization#GO:0051179;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000042964.1|UniProtKB=A0A5F8G3J3 A0A5F8G3J3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010017.4|UniProtKB=A0A5F8GVH4 A0A5F8GVH4 SMAD9 PTHR13703:SF41 SMAD SMAD FAMILY MEMBER 9 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;response to transforming growth factor beta#GO:0071559;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;response to BMP#GO:0071772;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular response to growth factor stimulus#GO:0071363;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor signaling pathway#GO:0007179;signal transduction#GO:0007165;cellular process#GO:0009987 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 TGF-beta signaling pathway#P00052>RSmads#P01292;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD1/5/8#P06787;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819 MONDO|Ensembl=ENSMODG00000048472.1|UniProtKB=F7AKN4 F7AKN4 LOC100028676 PTHR48002:SF153 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024984.2|UniProtKB=F6XNS5 F6XNS5 SLC35G2 PTHR22911:SF52 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G2 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 MONDO|Ensembl=ENSMODG00000029466.2|UniProtKB=K7E5Y3 K7E5Y3 PTHR44427:SF1 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CELL ADHESION MOLECULE CEACAM1 protein binding#GO:0005515;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000047332.1|UniProtKB=A0A5F8GYX9 A0A5F8GYX9 PANX3 PTHR15759:SF3 PANNEXIN PANNEXIN-3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000009417.4|UniProtKB=F7C5E7 F7C5E7 UPP1 PTHR43691:SF10 URIDINE PHOSPHORYLASE URIDINE PHOSPHORYLASE 1 glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763 nucleoside catabolic process#GO:0009164;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine phosphorylase#P03152 MONDO|Ensembl=ENSMODG00000003349.3|UniProtKB=F7CTD5 F7CTD5 DEF8 PTHR12326:SF3 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN DIFFERENTIALLY EXPRESSED IN FDCP 8 HOMOLOG MONDO|Ensembl=ENSMODG00000003265.4|UniProtKB=F6SJY7 F6SJY7 PTHR12308:SF15 ANOCTAMIN ANOCTAMIN molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;biological regulation#GO:0065007;membrane organization#GO:0061024;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000051423.1|UniProtKB=K7DYU8 K7DYU8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000744.4|UniProtKB=F6VPW1 F6VPW1 CSF2RB PTHR23037:SF22 CYTOKINE RECEPTOR CYTOKINE RECEPTOR COMMON SUBUNIT BETA transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;coreceptor activity#GO:0015026;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;cytokine-mediated signaling pathway#GO:0019221;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;response to peptide#GO:1901652;immunoglobulin mediated immune response#GO:0016064;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;immune response#GO:0006955;response to chemical#GO:0042221;response to cytokine#GO:0034097;adaptive immune response#GO:0002250;cell surface receptor signaling pathway via STAT#GO:0097696;biological regulation#GO:0065007;positive regulation of leukocyte proliferation#GO:0070665;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;regulation of leukocyte proliferation#GO:0070663 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974 MONDO|Ensembl=ENSMODG00000011597.5|UniProtKB=F6UZE6 F6UZE6 HCFC1 PTHR46003:SF3 HOST CELL FACTOR HOST CELL FACTOR 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000040099.1|UniProtKB=H9H9D2 H9H9D2 PTHR23226:SF425 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 24 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009574.4|UniProtKB=F7AX36 F7AX36 RBM22 PTHR14089:SF6 PRE-MRNA-SPLICING FACTOR RBM22 PRE-MRNA-SPLICING FACTOR RBM22 binding#GO:0005488;pre-mRNA binding#GO:0036002;nucleic acid binding#GO:0003676;snRNA binding#GO:0017069;RNA binding#GO:0003723 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000046498.1|UniProtKB=A0A5F8GKK5 A0A5F8GKK5 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000046954.1|UniProtKB=A0A5F8H6Q9 A0A5F8H6Q9 LOC100021070 PTHR24384:SF261 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 719 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000020258.4|UniProtKB=F7CJK0 F7CJK0 SSBP2 PTHR12610:SF23 SINGLE STRANDED DNA BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN 2 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000017601.4|UniProtKB=F7AHW4 F7AHW4 AGPAT2 PTHR10434:SF2 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE BETA acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000011252.4|UniProtKB=A0A5F8GA47 A0A5F8GA47 LOC100026618 PTHR24300:SF400 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C9 tetrapyrrole binding#GO:0046906;binding#GO:0005488;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;icosanoid metabolic process#GO:0006690;response to chemical#GO:0042221;cellular response to xenobiotic stimulus#GO:0071466;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;arachidonate metabolic process#GO:0019369;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;xenobiotic metabolic process#GO:0006805;olefinic compound metabolic process#GO:0120254;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000045373.1|UniProtKB=A0A5F8GBL1 A0A5F8GBL1 PTHR24068:SF543 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 D3 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;protein K48-linked ubiquitination#GO:0070936;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein K11-linked ubiquitination#GO:0070979;catabolic process#GO:0009056 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000012713.4|UniProtKB=F6TYF6 F6TYF6 ADAMTS17 PTHR13723:SF151 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 17 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000022860.2|UniProtKB=H9H9Q3 H9H9Q3 GPR141 PTHR24237:SF35 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 141-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 defense response#GO:0006952;cell communication#GO:0007154;inflammatory response#GO:0006954;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000051121.1|UniProtKB=A0A5F8HG12 A0A5F8HG12 VMA21 PTHR31792:SF3 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000036618.1|UniProtKB=A0A5F8GQR7 A0A5F8GQR7 VN2R588 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017107.4|UniProtKB=F6UKE3 F6UKE3 ZNF365 PTHR15739:SF2 ZINC FINGER PROTEIN PROTEIN ZNF365 regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;regulation of cellular component organization#GO:0051128;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;cellular component organization#GO:0016043;regulation of cellular response to stress#GO:0080135;regulation of DNA recombination#GO:0000018;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;regulation of plasma membrane bounded cell projection organization#GO:0120035;macromolecule metabolic process#GO:0043170;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of cell projection organization#GO:0031344;regulation of response to stress#GO:0080134;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;telomere organization#GO:0032200;regulation of double-strand break repair#GO:2000779 MONDO|Ensembl=ENSMODG00000011399.3|UniProtKB=F6SNL2 F6SNL2 LOC100619854 PTHR26450:SF31 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 645 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000042364.1|UniProtKB=A0A5F8H1J0 A0A5F8H1J0 TFB1M PTHR11727:SF17 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL transcription regulator activity#GO:0140110;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a rRNA#GO:0140102;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098 mitochondrial RNA metabolic process#GO:0000959;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;mitochondrial gene expression#GO:0140053;rRNA processing#GO:0006364;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;mitochondrial transcription#GO:0006390;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;methylation#GO:0032259;ribosome biogenesis#GO:0042254;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;DNA-templated transcription initiation#GO:0006352;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000041764.1|UniProtKB=A0A5F8HJA8 A0A5F8HJA8 HTD2 PTHR43437:SF3 HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL-RELATED HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000019079.3|UniProtKB=F7FNN2 F7FNN2 PRAG1 PTHR22972:SF3 SERINE/THREONINE PROTEIN KINASE INACTIVE TYROSINE-PROTEIN KINASE PRAG1 catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell motility#GO:2000145;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000037004.1|UniProtKB=A0A5F8H1R7 A0A5F8H1R7 RPL18A PTHR10052:SF1 60S RIBOSOMAL PROTEIN L18A LARGE RIBOSOMAL SUBUNIT PROTEIN EL20 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000003081.3|UniProtKB=F6PL69 F6PL69 MAFG PTHR10129:SF15 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFG sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of epithelial cell differentiation#GO:0030856;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell differentiation#GO:0045595;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000009491.3|UniProtKB=F7FN65 F7FN65 POLR3D PTHR13408:SF0 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;transferase complex, transferring phosphorus-containing groups#GO:0061695 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000000675.4|UniProtKB=F6X204 F6X204 ZFR2 PTHR45762:SF2 ZINC FINGER RNA-BINDING PROTEIN ZINC FINGER RNA-BINDING PROTEIN 2 single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000050385.1|UniProtKB=F6QCJ7 F6QCJ7 LOC100023985 PTHR48001:SF105 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037965.1|UniProtKB=F6S7I0 F6S7I0 PTHR24028:SF318 CADHERIN-87A PROTOCADHERIN BETA-16 cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000005161.4|UniProtKB=F7E8C6 F7E8C6 ADAMTS15 PTHR13723:SF39 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 15 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000019430.4|UniProtKB=F6SFK7 F6SFK7 MTHFS PTHR23407:SF1 ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE 5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 metabolic process#GO:0008152;tetrahydrofolate biosynthetic process#GO:0046654;tetrahydrofolate metabolic process#GO:0046653;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ligase#PC00142 MONDO|Ensembl=ENSMODG00000000087.4|UniProtKB=F6Q946 F6Q946 NOCT PTHR12121:SF45 CARBON CATABOLITE REPRESSOR PROTEIN 4 NOCTURNIN 3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098 regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000016960.4|UniProtKB=F6V5G0 F6V5G0 GRM3 PTHR24060:SF160 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 3 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Ionotropic glutamate receptor pathway#P00037>mGluR 2/3#P01014;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Metabotropic glutamate receptor group II pathway#P00040>mGluR2/3#P01048 MONDO|Ensembl=ENSMODG00000000631.2|UniProtKB=F6TAD7 F6TAD7 PDCD6 PTHR46212:SF3 PEFLIN PROGRAMMED CELL DEATH PROTEIN 6 MONDO|Ensembl=ENSMODG00000021322.3|UniProtKB=F7FT01 F7FT01 GHSR PTHR24243:SF7 G-PROTEIN COUPLED RECEPTOR GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000006543.4|UniProtKB=A0A5F8H7M9 A0A5F8H7M9 CEP104 PTHR13371:SF0 GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN CENTROSOMAL PROTEIN OF 104 KDA cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929 MONDO|Ensembl=ENSMODG00000000541.3|UniProtKB=F6XMM1 F6XMM1 ABCG8 PTHR13236:SF0 DYNEIN 2 LIGHT INTERMEDIATE CHAIN, ISOFORM 2 CYTOPLASMIC DYNEIN 2 LIGHT INTERMEDIATE CHAIN 1 binding#GO:0005488;protein binding#GO:0005515 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;intraciliary transport involved in cilium assembly#GO:0035735;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;intraciliary retrograde transport#GO:0035721;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782 microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;dynein complex#GO:0030286;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000001450.4|UniProtKB=A0A5F8GSW3 A0A5F8GSW3 SLC2A9 PTHR23503:SF35 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 9 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739;transport#GO:0006810;carbohydrate transport#GO:0008643;import into cell#GO:0098657;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000004060.4|UniProtKB=F7AK87 F7AK87 PTHR33426:SF43 C2H2-TYPE DOMAIN-CONTAINING PROTEIN NADH DEHYDROGENASE SUBUNIT 5 MONDO|Ensembl=ENSMODG00000001287.4|UniProtKB=F7C0A7 F7C0A7 CDCA7L PTHR31169:SF4 OS05G0300700 PROTEIN CELL DIVISION CYCLE-ASSOCIATED 7-LIKE PROTEIN intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000046965.1|UniProtKB=A0A5F8HCK5 A0A5F8HCK5 PTHR47398:SF1 PROLINE-RICH PROTEIN 3 PROLINE-RICH PROTEIN 3 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;protein-macromolecule adaptor activity#GO:0030674;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;molecular adaptor activity#GO:0060090;protein phosphatase inhibitor activity#GO:0004864;enzyme-substrate adaptor activity#GO:0140767;enzyme inhibitor activity#GO:0004857 regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular component organization#GO:0051130;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of protein-containing complex disassembly#GO:0043244;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000020807.3|UniProtKB=F6S7B5 F6S7B5 BMP2K PTHR22967:SF10 SERINE/THREONINE PROTEIN KINASE BMP-2-INDUCIBLE PROTEIN KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;phosphatase regulator activity#GO:0019208;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;enzyme regulator activity#GO:0030234 regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of Notch signaling pathway#GO:0045747;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;regulation of multicellular organismal development#GO:2000026;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;regulation of bone mineralization#GO:0030500;regulation of multicellular organismal process#GO:0051239;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of response to stimulus#GO:0048583;regulation of endocytosis#GO:0030100 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000006962.5|UniProtKB=F6QVE7 F6QVE7 ZBTB4 PTHR24388:SF58 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000011682.4|UniProtKB=F7GE78 F7GE78 GMNN PTHR13372:SF4 GEMININ GEMININ transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 negative regulation of cell cycle#GO:0045786;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated DNA replication initiation#GO:0030174;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA replication#GO:0006275;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of DNA-templated DNA replication#GO:0090329 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000028965.2|UniProtKB=K7E4I9 K7E4I9 LOC103098226 PTHR24329:SF303 HOMEOBOX PROTEIN ARISTALESS PAIRED MESODERM HOMEOBOX PROTEIN 2A DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000005440.4|UniProtKB=F7D0H9 F7D0H9 FANCD2 PTHR32086:SF0 FANCONI ANEMIA GROUP D2 PROTEIN FANCONI ANEMIA GROUP D2 PROTEIN protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 regulation of cellular process#GO:0050794;homologous recombination#GO:0035825;primary metabolic process#GO:0044238;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;sexual reproduction#GO:0019953;biological regulation#GO:0065007;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;nuclear chromosome segregation#GO:0098813;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;nucleic acid metabolic process#GO:0090304;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic DNA damage checkpoint signaling#GO:0044773;organelle fission#GO:0048285;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;meiosis I cell cycle process#GO:0061982;DNA damage checkpoint signaling#GO:0000077;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;DNA integrity checkpoint signaling#GO:0031570;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;meiotic chromosome segregation#GO:0045132;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;signaling#GO:0023052;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;negative regulation of mitotic cell cycle#GO:0045930;cellular response to stress#GO:0033554;cell cycle checkpoint signaling#GO:0000075;homologous chromosome pairing at meiosis#GO:0007129;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;metabolic process#GO:0008152;chromosome organization involved in meiotic cell cycle#GO:0070192;DNA recombination#GO:0006310;chromosome segregation#GO:0007059 condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000003489.2|UniProtKB=F7CSK1 F7CSK1 KXD1 PTHR13511:SF0 KXDL MOTIF-CONTAINING PROTEIN 1 KXDL MOTIF-CONTAINING PROTEIN 1 organelle localization#GO:0051640;lysosome localization#GO:0032418;localization#GO:0051179 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000015242.3|UniProtKB=F6UK35 F6UK35 PTHR21665:SF2 CATION CHANNEL SPERM-ASSOCIATED TARGETING SUBUNIT TAU CATION CHANNEL SPERM-ASSOCIATED TARGETING SUBUNIT TAU MONDO|Ensembl=ENSMODG00000017316.4|UniProtKB=F6WX13 F6WX13 REPS1 PTHR11216:SF63 EH DOMAIN RALBP1-ASSOCIATED EPS DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;import into cell#GO:0098657;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000011593.2|UniProtKB=F6UZP5 F6UZP5 PTHR13864:SF6 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED PROTEIN LYL-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000037761.1|UniProtKB=A0A5F8GTW5 A0A5F8GTW5 PTHR43340:SF6 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE metal ion binding#GO:0046872;magnesium ion binding#GO:0000287;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;IMP metabolic process#GO:0046040;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase metabolic process#GO:0009112;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247;Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804;Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245 MONDO|Ensembl=ENSMODG00000021527.2|UniProtKB=F7FSD2 F7FSD2 PGLYRP1 PTHR11022:SF58 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN RECOGNITION PROTEIN 1 N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;peptidoglycan muralytic activity#GO:0061783;pattern recognition receptor activity#GO:0038187;hydrolase activity#GO:0016787;molecular transducer activity#GO:0060089;catalytic activity#GO:0003824;signaling receptor activity#GO:0038023;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to Gram-positive bacterium#GO:0050830;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000021501.3|UniProtKB=A0A5F8H4D6 A0A5F8H4D6 PTHR23095:SF17 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN MA1 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000001585.4|UniProtKB=F7BBK5 F7BBK5 NFS1 PTHR11601:SF65 CYSTEINE DESULFURYLASE FAMILY MEMBER CYSTEINE DESULFURASE transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 cytosol#GO:0005829;nucleus#GO:0005634;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;lyase#PC00144 MONDO|Ensembl=ENSMODG00000048920.1|UniProtKB=A0A5F8G9V6 A0A5F8G9V6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000041702.1|UniProtKB=F7F882 F7F882 PTHR23087:SF12 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-14 binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000013328.4|UniProtKB=A0A5F8HH08 A0A5F8HH08 SLC37A4 PTHR43826:SF3 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;phosphate transmembrane transporter activity#GO:0005315 transport#GO:0006810;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;phosphate ion transport#GO:0006817;organophosphate ester transport#GO:0015748 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000016156.2|UniProtKB=F7CMZ1 F7CMZ1 LOC100022788 PTHR26453:SF169 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2W1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010742.4|UniProtKB=F7FWV4 F7FWV4 LOC100028888 PTHR24377:SF975 IP01015P-RELATED ZINC FINGER PROTEIN 883-LIKE transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025594.3|UniProtKB=F6U215 F6U215 LOC103098786 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375 signaling#GO:0023052;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of immune response#GO:0050776 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000024010.2|UniProtKB=F6YQ48 F6YQ48 PTHR42951:SF4 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING ACYL-COENZYME A THIOESTERASE MBLAC2 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000049998.1|UniProtKB=A0A5F8GZF0 A0A5F8GZF0 DUSP5 PTHR10159:SF40 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 5 phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824 anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;multicellular organismal process#GO:0032501;tissue development#GO:0009888;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;formation of primary germ layer#GO:0001704;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;gastrulation#GO:0007369;negative regulation of biological process#GO:0048519;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of MAPK cascade#GO:0043408;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;endoderm development#GO:0007492;anatomical structure formation involved in morphogenesis#GO:0048646;cellular process#GO:0009987;signal transduction#GO:0007165;endoderm formation#GO:0001706;embryo development#GO:0009790;negative regulation of signal transduction#GO:0009968 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000000648.3|UniProtKB=F6SUE6 F6SUE6 LRPPRC PTHR46669:SF1 LEUCINE-RICH PPR MOTIF-CONTAINING PROTEIN, MITOCHONDRIAL LEUCINE-RICH PPR MOTIF-CONTAINING PROTEIN, MITOCHONDRIAL mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000004728.3|UniProtKB=F6Y235 F6Y235 GSPT1 PTHR23115:SF36 TRANSLATION FACTOR G1 TO S PHASE TRANSITION 2 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 translational termination#GO:0006415;translation#GO:0006412;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;protein-containing complex disassembly#GO:0032984;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation factor#PC00223 MONDO|Ensembl=ENSMODG00000007041.4|UniProtKB=F6UFL2 F6UFL2 GPR107 PTHR21229:SF12 LUNG SEVEN TRANSMEMBRANE RECEPTOR PROTEIN GPR107 clathrin binding#GO:0030276;binding#GO:0005488;protein binding#GO:0005515 transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897 clathrin-coated vesicle#GO:0030136;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012296.4|UniProtKB=A0A5F8GA93 A0A5F8GA93 ATP5MC1 PTHR10031:SF56 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, MITOCHONDRIAL primary active transporter#PC00068;transporter#PC00227;ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000047652.1|UniProtKB=A0A5F8HHR3 A0A5F8HHR3 RBM8A PTHR45894:SF1 RNA-BINDING PROTEIN 8A RNA-BINDING PROTEIN 8A nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exon-exon junction complex#GO:0035145;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000021486.4|UniProtKB=F7G2W9 F7G2W9 PTHR45884:SF1 N-ACETYLTRANSFERASE ECO N-ACETYLTRANSFERASE ESCO1 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;protein N-acyltransferase activity#GO:0140186 chromosome organization#GO:0051276;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;mitotic sister chromatid cohesion#GO:0007064 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000017187.3|UniProtKB=A0A5F8G4R6 A0A5F8G4R6 ANAPC2 PTHR45957:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cell cycle#GO:0007049;protein K11-linked ubiquitination#GO:0070979;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;mitotic cell cycle#GO:0000278;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;protein modification by small protein conjugation or removal#GO:0070647;mitotic cell cycle phase transition#GO:0044772;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of chromosome organization#GO:0033044;metabolic process#GO:0008152;metaphase/anaphase transition of cell cycle#GO:0044784;regulation of chromosome segregation#GO:0051983;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047 cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535 Cell cycle#P00013>APC#P00481 MONDO|Ensembl=ENSMODG00000010487.3|UniProtKB=F7ESH7 F7ESH7 PTHR10501:SF30 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B RNA BINDING PROTEIN, MRNA PROCESSING FACTOR 2-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;negative regulation of cellular process#GO:0048523;negative regulation of biological process#GO:0048519;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000000753.4|UniProtKB=A0A5F8GZX1 A0A5F8GZX1 SIX3 PTHR10390:SF31 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX3 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;visual system development#GO:0150063;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;sensory system development#GO:0048880;regulation of primary metabolic process#GO:0080090;head development#GO:0060322;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000005100.4|UniProtKB=F6ZEA7 F6ZEA7 NDST3 PTHR10605:SF29 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE 3 deacetylase activity#GO:0019213;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824;deacylase activity#GO:0160215 biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000009798.5|UniProtKB=F6SYT4 F6SYT4 HMGXB3 PTHR17609:SF2 HMG DOMAIN-CONTAINING PROTEIN 3 HMG DOMAIN-CONTAINING PROTEIN 3 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000029365.2|UniProtKB=K7E2P9 K7E2P9 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED RETROVIRAL ENVELOPE PROTEIN GP41-LIKE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000027940.2|UniProtKB=K7E4B8 K7E4B8 TEN1 PTHR33905:SF1 CST COMPLEX SUBUNIT TEN1 CST COMPLEX SUBUNIT TEN1 binding#GO:0005488;nucleic acid binding#GO:0003676;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;DNA binding#GO:0003677;enzyme inhibitor activity#GO:0004857;sequence-specific DNA binding#GO:0043565;molecular function regulator activity#GO:0098772;telomeric repeat DNA binding#GO:0042162 negative regulation of chromosome organization#GO:2001251;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of telomere maintenance#GO:0032204;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of telomere maintenance via telomere lengthening#GO:1904356;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053 intracellular organelle#GO:0043229;nuclear telomere cap complex#GO:0000783;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;chromosome#GO:0005694;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromosome, telomeric region#GO:0000781 MONDO|Ensembl=ENSMODG00000014082.4|UniProtKB=F6R4X5 F6R4X5 RAI1 PTHR14955:SF6 RETINOIC ACID INDUCED 1/TRANSCRIPTION FACTOR 20 RETINOIC ACID-INDUCED PROTEIN 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;circadian regulation of gene expression#GO:0032922;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;circadian rhythm#GO:0007623;rhythmic process#GO:0048511 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000000207.4|UniProtKB=F6TF29 F6TF29 RHOV PTHR24072:SF144 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOV heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;actin filament organization#GO:0007015;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;establishment or maintenance of cell polarity#GO:0007163;actin filament-based process#GO:0030029;localization#GO:0051179;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000018347.4|UniProtKB=F6PR25 F6PR25 LOC100014247 PTHR14952:SF12 ROPPORIN-1-LIKE PROTEIN ROPPORIN-1B cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;developmental maturation#GO:0021700;male gamete generation#GO:0048232;sperm capacitation#GO:0048240;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;cell maturation#GO:0048469;cellular developmental process#GO:0048869;microtubule-based process#GO:0007017;developmental process involved in reproduction#GO:0003006;anatomical structure maturation#GO:0071695;sperm motility#GO:0097722;germ cell development#GO:0007281;cell differentiation#GO:0030154;gamete generation#GO:0007276;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;cell development#GO:0048468;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;sexual reproduction#GO:0019953;spermatid development#GO:0007286;cilium-dependent cell motility#GO:0060285;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609 cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929 MONDO|Ensembl=ENSMODG00000005816.5|UniProtKB=F6WY53 F6WY53 KRI1 PTHR14490:SF5 ZINC FINGER, ZZ TYPE PROTEIN KRI1 HOMOLOG gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit biogenesis#GO:0042274;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 90S preribosome#GO:0030686;organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000015335.4|UniProtKB=F6XET7 F6XET7 CREB5 PTHR19304:SF8 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 5 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic leucine zipper transcription factor#PC00056 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713 MONDO|Ensembl=ENSMODG00000041589.1|UniProtKB=F7EMI1 F7EMI1 LOC100618547 PTHR26453:SF301 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013114.5|UniProtKB=F7BMQ2 F7BMQ2 SALL1 PTHR23233:SF51 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000017669.4|UniProtKB=F7GG02 F7GG02 C2H6orf58 PTHR18820:SF1 LEG1 PROTEIN LEG1 HOMOLOG cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000010475.5|UniProtKB=A0A5F8GIA1 A0A5F8GIA1 PTHR12845:SF8 GUANINE NUCLEOTIDE EXCHANGE FACTOR EPHEXIN-1 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of actin filament-based process#GO:0032970;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000018544.4|UniProtKB=F6ZQH8 F6ZQH8 PTHR47969:SF31 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED KINESIN-LIKE PROTEIN KIF21A ISOFORM X1 microtubule motor activity#GO:0003777;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cell cycle#GO:0007049;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle process#GO:0022402 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000012258.3|UniProtKB=F6YGJ6 F6YGJ6 PKD2L2 PTHR10877:SF47 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-2-LIKE PROTEIN 2 passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 response to mechanical stimulus#GO:0009612;detection of stimulus#GO:0051606;detection of mechanical stimulus#GO:0050982;response to abiotic stimulus#GO:0009628;response to external stimulus#GO:0009605;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000040133.1|UniProtKB=A0A5F8GG05 A0A5F8GG05 NEK8 PTHR44535:SF4 PROTEIN CBG16200 SERINE_THREONINE-PROTEIN KINASE NEK8 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 heart development#GO:0007507;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;determination of bilateral symmetry#GO:0009855;multicellular organism development#GO:0007275;animal organ development#GO:0048513;specification of symmetry#GO:0009799;developmental process#GO:0032502;left/right pattern formation#GO:0060972;regulation of response to stimulus#GO:0048583;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;determination of left/right symmetry#GO:0007368;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;pattern specification process#GO:0007389;regulation of signaling#GO:0023051 plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929 MONDO|Ensembl=ENSMODG00000019246.4|UniProtKB=F6QTG2 F6QTG2 SARM1 PTHR22998:SF1 SARM1 NAD(+) HYDROLASE SARM1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824 pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;pyridine nucleotide catabolic process#GO:0019364;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;NAD+ metabolic process#GO:0019674;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing compound metabolic process#GO:0006139 plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cell body#GO:0044297;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000044245.1|UniProtKB=A0A5F8GNV7 A0A5F8GNV7 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017943.3|UniProtKB=F7E3R4 F7E3R4 PTHR24232:SF91 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006662.4|UniProtKB=F7FTD0 F7FTD0 DNAL1 PTHR10824:SF39 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COA THIOESTERASE 6 thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;acyl-CoA hydrolase activity#GO:0016289;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;deacylase activity#GO:0160215;hydrolase activity#GO:0016787 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 esterase#PC00097 MONDO|Ensembl=ENSMODG00000046929.1|UniProtKB=A0A5F8G9S8 A0A5F8G9S8 SMIM18 PTHR36982:SF1 CLCA DOMAIN-CONTAINING PROTEIN SMALL INTEGRAL MEMBRANE PROTEIN 18 MONDO|Ensembl=ENSMODG00000045729.1|UniProtKB=A0A5F8H6J9 A0A5F8H6J9 LOC100022188 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;antioxidant activity#GO:0016209;transferase activity#GO:0016740;catalytic activity#GO:0003824;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;glutathione transferase activity#GO:0004364 modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000024839.2|UniProtKB=F7F9C0 F7F9C0 PTHR14102:SF4 PAR-6-RELATED PARTITIONING DEFECTIVE 6 HOMOLOG BETA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell-cell junction organization#GO:0045216;establishment or maintenance of cell polarity#GO:0007163;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cell-cell junction maintenance#GO:0045217;centrosome cycle#GO:0007098;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cell junction organization#GO:0034330 plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;protein kinase complex#GO:1902911;transferase complex#GO:1990234;apical part of cell#GO:0045177;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;apical plasma membrane#GO:0016324;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 cell junction protein#PC00070;tight junction#PC00214 MONDO|Ensembl=ENSMODG00000048982.1|UniProtKB=A0A5F8G6Y3 A0A5F8G6Y3 HSFX PTHR10015:SF336 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK TRANSCRIPTION FACTOR, Y-LINKED winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000008039.2|UniProtKB=F6ZAJ3 F6ZAJ3 IL12B PTHR48485:SF4 INTERLEUKIN-12 SUBUNIT BETA-RELATED INTERLEUKIN-12 SUBUNIT BETA protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;cytokine activity#GO:0005125;cytokine binding#GO:0019955;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851 cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007;signaling#GO:0023052 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000004982.3|UniProtKB=A0A5F8HLA1 A0A5F8HLA1 RTKN PTHR21538:SF19 ANILLIN/RHOTEKIN RTKN RHOTEKIN enzyme inhibitor activity#GO:0004857;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 septin cytoskeleton organization#GO:0032185;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;actomyosin contractile ring assembly#GO:0000915;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cytokinesis#GO:0000910;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cytokinetic process#GO:0032506;cortical actin cytoskeleton organization#GO:0030866;cytoskeleton-dependent cytokinesis#GO:0061640;septin ring organization#GO:0031106;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell division#GO:0051301;cell cycle process#GO:0022402;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;mitotic cell cycle#GO:0000278;actomyosin structure organization#GO:0031032 cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;actomyosin contractile ring#GO:0005826;contractile ring#GO:0070938;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000013976.4|UniProtKB=F6R624 F6R624 LOC100015440 PTHR24064:SF283 SOLUTE CARRIER FAMILY 22 MEMBER ORGANIC CATION_CARNITINE TRANSPORTER 2 quaternary ammonium group transmembrane transporter activity#GO:0015651;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;transport#GO:0006810;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000039978.1|UniProtKB=A0A5F8GWD6 A0A5F8GWD6 TBX1 PTHR11267:SF104 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 MONDO|Ensembl=ENSMODG00000045282.1|UniProtKB=K7E447 K7E447 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000038070.1|UniProtKB=A0A5F8GKH7 A0A5F8GKH7 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000025462.3|UniProtKB=F6RK26 F6RK26 PTHR23268:SF47 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 11-1 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000037238.1|UniProtKB=A0A5F8GVE9 A0A5F8GVE9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000020083.3|UniProtKB=A0A5F8GZ79 A0A5F8GZ79 APLNR PTHR24228:SF31 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR APELIN RECEPTOR molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;heart development#GO:0007507;multicellular organismal process#GO:0032501;developmental process#GO:0032502;vasculature development#GO:0001944;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000006516.4|UniProtKB=F7E466 F7E466 VKORC1L1 PTHR14519:SF5 VITAMIN K EPOXIDE REDUCTASE COMPLEX, SUBUNIT 1 VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1-LIKE PROTEIN 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;metabolic process#GO:0008152;vitamin K metabolic process#GO:0042373;ketone metabolic process#GO:0042180 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000016863.4|UniProtKB=F6WQP9 F6WQP9 KCNQ2 PTHR11537:SF6 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 2 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;cellular process#GO:0009987;potassium ion transport#GO:0006813;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;action potential#GO:0001508;metal ion transport#GO:0030001 membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 voltage-gated ion channel#PC00241;ion channel#PC00133 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>K+ channel#P01070 MONDO|Ensembl=ENSMODG00000024867.3|UniProtKB=F6ZHK9 F6ZHK9 PTHR45713:SF20 FTP DOMAIN-CONTAINING PROTEIN PENTRAXIN PRECURSOR MONDO|Ensembl=ENSMODG00000010006.4|UniProtKB=F6URR5 F6URR5 RDH12 PTHR24320:SF227 RETINOL DEHYDROGENASE RETINOL DEHYDROGENASE 12 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 hormone metabolic process#GO:0042445;biological regulation#GO:0065007;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;olefinic compound metabolic process#GO:0120254;retinol metabolic process#GO:0042572;terpenoid metabolic process#GO:0006721 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000043278.1|UniProtKB=A0A5F8G9I3 A0A5F8G9I3 MUL1 PTHR12183:SF4 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;ubiquitin-like protein transferase activity#GO:0019787 regulation of anatomical structure morphogenesis#GO:0022603;protein stabilization#GO:0050821;positive regulation of developmental process#GO:0051094;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;regulation of protein stability#GO:0031647;positive regulation of cellular process#GO:0048522;positive regulation of organelle organization#GO:0010638;regulation of biological quality#GO:0065008;positive regulation of cellular component organization#GO:0051130;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of mitochondrial fission#GO:0090140;positive regulation of mitochondrial fission#GO:0090141;regulation of developmental process#GO:0050793;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000020116.4|UniProtKB=F7E9X7 F7E9X7 CTNND1 PTHR10372:SF6 PLAKOPHILLIN-RELATED CATENIN DELTA-1 protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;cell junction#GO:0030054;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912 intermediate filament#PC00129;cytoskeletal protein#PC00085;intermediate filament binding protein#PC00130 Cadherin signaling pathway#P00012>P120#P00473 MONDO|Ensembl=ENSMODG00000025450.3|UniProtKB=H9H9R3 H9H9R3 PTHR11860:SF62 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 9 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000036517.1|UniProtKB=A0A5F8GBJ6 A0A5F8GBJ6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013330.3|UniProtKB=F7GJ67 F7GJ67 TRAPPC4 PTHR23249:SF15 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 4 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;TRAPP complex#GO:0030008 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000013540.3|UniProtKB=F7CLY1 F7CLY1 POLR2C PTHR11800:SF2 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA-templated transcription#GO:0006351;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 MONDO|Ensembl=ENSMODG00000036869.1|UniProtKB=A0A5F8G6D9 A0A5F8G6D9 HS3ST5 PTHR10605:SF46 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 5 catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000038810.1|UniProtKB=A0A5F8GLT7 A0A5F8GLT7 NUAK2 PTHR24343:SF133 SERINE/THREONINE KINASE NUAK FAMILY SNF1-LIKE KINASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 response to stimulus#GO:0050896;response to nutrient levels#GO:0031667;response to starvation#GO:0042594;response to stress#GO:0006950;cellular response to glucose starvation#GO:0042149;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;cellular response to stress#GO:0033554 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000003712.4|UniProtKB=A0A5F8GL54 A0A5F8GL54 SLC35A3 PTHR10231:SF36 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-N-ACETYLGLUCOSAMINE TRANSPORTER organophosphate ester transmembrane transporter activity#GO:0015605;UDP-galactose transmembrane transporter activity#GO:0005459;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 transporter#PC00227 MONDO|Ensembl=ENSMODG00000001080.3|UniProtKB=F7GHY7 F7GHY7 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 MONDO|Ensembl=ENSMODG00000006072.4|UniProtKB=A0A5F8H220 A0A5F8H220 UBN1 PTHR21669:SF12 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS UBINUCLEIN-1 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000042981.1|UniProtKB=A0A5F8GZH7 A0A5F8GZH7 PTHR24381:SF27 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 180 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000001472.4|UniProtKB=F7AP56 F7AP56 LONRF2 PTHR23327:SF5 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 2 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron projection development#GO:0031175;cellular process#GO:0009987;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;protein catabolic process#GO:0030163;generation of neurons#GO:0048699;neuron apoptotic process#GO:0051402;neuron development#GO:0048666;cellular component organization#GO:0016043;apoptotic process#GO:0006915;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;developmental process#GO:0032502;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;neurogenesis#GO:0022008;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;system development#GO:0048731;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;cell death#GO:0008219;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000024950.2|UniProtKB=F6UU62 F6UU62 LCOR PTHR14931:SF2 GENE 340-RELATED LIGAND DEPENDENT NUCLEAR RECEPTOR COREPRESSOR MONDO|Ensembl=ENSMODG00000009565.4|UniProtKB=F7BJ45 F7BJ45 HOXD11 PTHR46092:SF2 HOMEOBOX PROTEIN HOX-A11-RELATED HOMEOBOX PROTEIN HOX-D11 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;skeletal system development#GO:0001501;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;regulation of metabolic process#GO:0019222;skeletal system morphogenesis#GO:0048705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000037214.1|UniProtKB=A0A5F8GQK8 A0A5F8GQK8 PTHR48001:SF27 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000041636.1|UniProtKB=A0A5F8G8A9 A0A5F8G8A9 PTHR38503:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 1 SMALL INTEGRAL MEMBRANE PROTEIN 1 immune system process#GO:0002376;developmental process#GO:0032502;homeostasis of number of cells#GO:0048872;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;erythrocyte differentiation#GO:0030218;multicellular organismal-level homeostasis#GO:0048871;cellular process#GO:0009987;multicellular organismal process#GO:0032501;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;cell development#GO:0048468;homeostatic process#GO:0042592;hemopoiesis#GO:0030097 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000005927.4|UniProtKB=F6WX28 F6WX28 FOS PTHR23351:SF4 FOS TRANSCRIPTION FACTOR-RELATED PROTEIN C-FOS sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 Gonadotropin-releasing hormone receptor pathway#P06664>c-fos#G06680;Apoptosis signaling pathway#P00006>Fos#P00317;B cell activation#P00010>fos#P00380;Interleukin signaling pathway#P00036>c-fos#P00967;Gonadotropin-releasing hormone receptor pathway#P06664>c-fos#G06894;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>c-fos#P00884;CCKR signaling map#P06959>FOS#G06973;CCKR signaling map#P06959>FOS#G07266;T cell activation#P00053>fos#P01309;CCKR signaling map#P06959>FOS#P07035;Gonadotropin-releasing hormone receptor pathway#P06664>FOS#P06709;Angiogenesis#P00005>c-Fos#P00235;Huntington disease#P00029>Fos protein#P00801;PDGF signaling pathway#P00047>c-fos#P01145 MONDO|Ensembl=ENSMODG00000000912.4|UniProtKB=F6ZHD1 F6ZHD1 ADGRL4 PTHR12011:SF59 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR L4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000011040.4|UniProtKB=F7F446 F7F446 CALHM2 PTHR32261:SF3 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 2 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000017299.3|UniProtKB=F6S4Q3 F6S4Q3 CREB3L4 PTHR45996:SF2 AGAP001464-PB CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 MONDO|Ensembl=ENSMODG00000013125.4|UniProtKB=A0A5F8GV30 A0A5F8GV30 DAAM2 PTHR45725:SF7 FORMIN HOMOLOGY 2 FAMILY MEMBER DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 2 regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;positive regulation of signal transduction#GO:0009967;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of nervous system development#GO:0051960;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;positive regulation of canonical Wnt signaling pathway#GO:0090263 MONDO|Ensembl=ENSMODG00000019566.4|UniProtKB=A0A5F8GNN1 A0A5F8GNN1 RAB3C PTHR47980:SF15 LD44762P RAS-RELATED PROTEIN RAB-3C protein binding#GO:0005515;myosin binding#GO:0017022;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 transport#GO:0006810;secretion by cell#GO:0032940;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503;cell junction#GO:0030054 Synaptic vesicle trafficking#P05734>Rab3A#P05780 MONDO|Ensembl=ENSMODG00000006901.4|UniProtKB=A0A5F8H8K2 A0A5F8H8K2 NPL PTHR12128:SF21 DIHYDRODIPICOLINATE SYNTHASE N-ACETYLNEURAMINATE LYASE catalytic activity#GO:0003824;lyase activity#GO:0016829 lyase#PC00144 N-acetylglucosamine metabolism#P02756>N-acetylneuraminate lyase#P03040 MONDO|Ensembl=ENSMODG00000003209.4|UniProtKB=F6TZK5 F6TZK5 CPZ PTHR11532:SF63 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE Z metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190 MONDO|Ensembl=ENSMODG00000015169.4|UniProtKB=F7CET2 F7CET2 SDR42E1 PTHR10366:SF816 NAD DEPENDENT EPIMERASE/DEHYDRATASE SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E MEMBER 1 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 lyase#PC00144;dehydratase#PC00091;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000037652.1|UniProtKB=A0A5F8GFB8 A0A5F8GFB8 LOC100014413 PTHR24381:SF438 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 425 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000015725.3|UniProtKB=F7B5N9 F7B5N9 PTHR23104:SF15 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN CELL GROWTH REGULATOR WITH EF HAND DOMAIN PROTEIN 1 regulation of cell growth#GO:0001558;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cell growth#GO:0030308;negative regulation of biological process#GO:0048519;regulation of growth#GO:0040008;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000005074.4|UniProtKB=F7A813 F7A813 PTHR12080:SF54 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE T-CELL SURFACE ANTIGEN CD2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;T cell activation#GO:0042110;cell communication#GO:0007154;cell activation#GO:0001775;immune system process#GO:0002376;biological regulation#GO:0065007;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000020385.4|UniProtKB=F7F663 F7F663 MYRFL PTHR13029:SF17 FAMILY NOT NAMED MYELIN REGULATORY FACTOR-LIKE PROTEIN DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;proteolysis#GO:0006508;regulation of biological process#GO:0050789;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;protein maturation#GO:0051604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000017942.4|UniProtKB=F7E3Q7 F7E3Q7 PLA2G4E PTHR10728:SF24 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 EPSILON phospholipid binding#GO:0005543;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;small molecule binding#GO:0036094;ion binding#GO:0043167;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;lipid binding#GO:0008289 glycerophospholipid catabolic process#GO:0046475;organophosphate catabolic process#GO:0046434;metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;lipid metabolic process#GO:0006629;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000013456.4|UniProtKB=F7G987 F7G987 NCCRP1 PTHR12125:SF1 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 50 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000017099.4|UniProtKB=F6V307 F6V307 PTHR28457:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 CILIARY-ASSOCIATED CALCIUM-BINDING COILED-COIL PROTEIN 1 MONDO|Ensembl=ENSMODG00000041473.1|UniProtKB=A0A5F8H778 A0A5F8H778 LOC100028587 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000009505.3|UniProtKB=F7F9K7 F7F9K7 SPMIP5 PTHR47301:SF1 HYPOTHETICAL PROTEIN LOC681006 SPERM-ASSOCIATED MICROTUBULE INNER PROTEIN 5 MONDO|Ensembl=ENSMODG00000007641.4|UniProtKB=F7AYM4 F7AYM4 NUDCD2 PTHR12356:SF18 NUCLEAR MOVEMENT PROTEIN NUDC NUDC DOMAIN-CONTAINING PROTEIN 2 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000013339.4|UniProtKB=F7GAF6 F7GAF6 ZSWIM9 PTHR47086:SF1 BTB DOMAIN-CONTAINING PROTEIN ZINC FINGER SWIM-TYPE CONTAINING 9 MONDO|Ensembl=ENSMODG00000013815.4|UniProtKB=F6SXC0 F6SXC0 IL1B PTHR10078:SF30 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-1 BETA receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 regulation of mononuclear cell proliferation#GO:0032944;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;cellular response to lipid#GO:0071396;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of mononuclear cell proliferation#GO:0032946;regulation of leukocyte proliferation#GO:0070663;response to lipopolysaccharide#GO:0032496;positive regulation of multicellular organismal process#GO:0051240;response to molecule of bacterial origin#GO:0002237;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;positive regulation of response to stimulus#GO:0048584;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of leukocyte proliferation#GO:0070665;regulation of response to stimulus#GO:0048583;defense response#GO:0006952;cellular response to biotic stimulus#GO:0071216;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of T cell proliferation#GO:0042129;regulation of cell communication#GO:0010646;cytokine-mediated signaling pathway#GO:0019221;positive regulation of lymphocyte activation#GO:0051251;regulation of cell population proliferation#GO:0042127;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;positive regulation of cell-cell adhesion#GO:0022409;regulation of T cell activation#GO:0050863;response to lipid#GO:0033993;response to chemical#GO:0042221;response to cytokine#GO:0034097;positive regulation of T cell activation#GO:0050870;regulation of multicellular organismal process#GO:0051239;positive regulation of leukocyte activation#GO:0002696;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of cell population proliferation#GO:0008284;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;positive regulation of T cell proliferation#GO:0042102;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of intracellular signal transduction#GO:1902533;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;positive regulation of cell adhesion#GO:0045785;positive regulation of cell communication#GO:0010647;response to external biotic stimulus#GO:0043207;response to bacterium#GO:0009617;positive regulation of lymphocyte proliferation#GO:0050671;inflammatory response#GO:0006954;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;interleukin superfamily#PC00128;cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 MONDO|Ensembl=ENSMODG00000000032.4|UniProtKB=F6S0C4 F6S0C4 BMPER PTHR11339:SF272 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED BMP-BINDING ENDOTHELIAL REGULATOR PROTEIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 vasculature development#GO:0001944;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of vasculature development#GO:1901342;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of angiogenesis#GO:0045765;system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;regulation of developmental process#GO:0050793;circulatory system development#GO:0072359;blood vessel development#GO:0001568;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000000115.4|UniProtKB=A0A5F8GLT0 A0A5F8GLT0 LOC103097953 PTHR42902:SF2 MALATE SYNTHASE MALATE SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;glyoxylate metabolic process#GO:0046487;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000045009.1|UniProtKB=A0A5F8GDD5 A0A5F8GDD5 monDomV1R1241 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038588.1|UniProtKB=F6PYP7 F6PYP7 PTHR26450:SF411 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51A7 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016175.4|UniProtKB=F7G8Q0 F7G8Q0 PTHR19277:SF122 PENTRAXIN PENTRAXIN-4 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000037614.1|UniProtKB=A0A5F8HB45 A0A5F8HB45 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000020284.3|UniProtKB=F7C0F5 F7C0F5 GHR PTHR23036:SF108 CYTOKINE RECEPTOR GROWTH HORMONE RECEPTOR protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to hormone#GO:0009725;cell surface receptor signaling pathway#GO:0007166;cellular response to peptide hormone stimulus#GO:0071375;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cytokine-mediated signaling pathway#GO:0019221;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;positive regulation of response to stimulus#GO:0048584;cellular response to nitrogen compound#GO:1901699;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425 cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027501.2|UniProtKB=K7DZN1 K7DZN1 PTHR33064:SF44 POL PROTEIN RIBONUCLEASE H MONDO|Ensembl=ENSMODG00000014163.4|UniProtKB=F7G9D7 F7G9D7 TCF7 PTHR10373:SF33 TRANSCRIPTION FACTOR 7 FAMILY MEMBER TRANSCRIPTION FACTOR 7 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Wnt signaling pathway#P00057>TCF#P01437;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Gonadotropin-releasing hormone receptor pathway#P06664>TCF#P06701;Angiogenesis#P00005>TCF#P00242 MONDO|Ensembl=ENSMODG00000041508.1|UniProtKB=F7GID2 F7GID2 LOC100024933 PTHR26452:SF85 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048375.1|UniProtKB=A0A5F8H0M4 A0A5F8H0M4 PTHR14309:SF8 EXPRESSED PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY B MEMBER 2 membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000048637.1|UniProtKB=F6W427 F6W427 VN2R541 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000029020.2|UniProtKB=K7DYX3 K7DYX3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001310.4|UniProtKB=F7BEM8 F7BEM8 MAN2A1 PTHR11607:SF69 ALPHA-MANNOSIDASE ALPHA-MANNOSIDASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 hydrolase#PC00121;glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000044793.1|UniProtKB=A0A5F8H1H0 A0A5F8H1H0 monDomV1R1286 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000044456.1|UniProtKB=A0A5F8GBN1 A0A5F8GBN1 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000020580.4|UniProtKB=F7A177 F7A177 SHISA3 PTHR31395:SF4 SHISA PROTEIN SHISA-3 HOMOLOG scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000023521.3|UniProtKB=F6Z242 F6Z242 LOC100013054 PTHR12929:SF4 SOLUTE CARRIER FAMILY 52 SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;vitamin transport#GO:0051180;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000011358.4|UniProtKB=F6T5C4 F6T5C4 PTHR45971:SF2 PHOX (PX) DOMAIN-CONTAINING PROTEIN PROTEIN ASSOCIATED WITH UVRAG AS AUTOPHAGY ENHANCER lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;binding#GO:0005488 cellular component organization#GO:0016043;protein-containing complex disassembly#GO:0032984;vesicle fusion#GO:0006906;catabolic process#GO:0009056;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;cellular component disassembly#GO:0022411;autophagy#GO:0006914;cellular process#GO:0009987;membrane fusion#GO:0061025;organelle organization#GO:0006996;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;macroautophagy#GO:0016236;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;transport#GO:0006810;metabolic process#GO:0008152;autophagosome maturation#GO:0097352;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;intracellular organelle#GO:0043229;autophagosome#GO:0005776 MONDO|Ensembl=ENSMODG00000003022.4|UniProtKB=F6Q2M1 F6Q2M1 HECTD4 PTHR46435:SF1 E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED glucose homeostasis#GO:0042593;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;carbohydrate homeostasis#GO:0033500 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000016176.4|UniProtKB=F7G8P6 F7G8P6 AEBP1 PTHR11532:SF48 PROTEASE M14 CARBOXYPEPTIDASE ADIPOCYTE ENHANCER-BINDING PROTEIN 1 DNA-binding transcription repressor activity#GO:0001217;exopeptidase activity#GO:0008238;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;peptidase activity#GO:0008233;metalloexopeptidase activity#GO:0008235;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;metallopeptidase activity#GO:0008237;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 regulation of RNA metabolic process#GO:0051252;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;proteolysis#GO:0006508;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190 MONDO|Ensembl=ENSMODG00000046587.1|UniProtKB=F6SEU9 F6SEU9 PTHR24100:SF64 BUTYROPHILIN BUTYROPHILIN, SUBFAMILY 3, MEMBER A3-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000047666.1|UniProtKB=A0A5F8GUL9 A0A5F8GUL9 C8orf88 PTHR12669:SF15 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN CHROMOSOME 8 OPEN READING FRAME 88 protein binding#GO:0005515;translation initiation factor binding#GO:0031369;translation regulator activity#GO:0045182;binding#GO:0005488 negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of translation#GO:0017148;regulation of translational initiation#GO:0006446;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 translation initiation factor#PC00224;translation factor#PC00223 MONDO|Ensembl=ENSMODG00000010434.4|UniProtKB=F6YTJ9 F6YTJ9 UROS PTHR12390:SF0 UROPORPHYRINOGEN III SYNTHASE UROPORPHYRINOGEN-III SYNTHASE hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;porphyrin-containing compound biosynthetic process#GO:0006779;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;porphyrin-containing compound metabolic process#GO:0006778;small molecule biosynthetic process#GO:0044283 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Heme biosynthesis#P02746>Uroporphyrinogen-III synthase#P02974 MONDO|Ensembl=ENSMODG00000015097.4|UniProtKB=F7F390 F7F390 PTHR48169:SF3 DED DOMAIN-CONTAINING PROTEIN CASP8 AND FADD-LIKE APOPTOSIS REGULATOR negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;negative regulation of programmed cell death#GO:0043069;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of extrinsic apoptotic signaling pathway#GO:2001236;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057 MONDO|Ensembl=ENSMODG00000041250.1|UniProtKB=A0A5F8GUT7 A0A5F8GUT7 LOC100011448 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023559.3|UniProtKB=F6UZD5 F6UZD5 PTHR24377:SF878 IP01015P-RELATED ZINC FINGER PROTEIN 670 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002598.2|UniProtKB=F7G4W7 F7G4W7 GSS PTHR11130:SF0 GLUTATHIONE SYNTHETASE GLUTATHIONE SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 biosynthetic process#GO:0009058;peptide metabolic process#GO:0006518;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ligase#PC00142 MONDO|Ensembl=ENSMODG00000028074.2|UniProtKB=K7E4U9 K7E4U9 IZUMO3 PTHR36470:SF1 IZUMO SPERM-EGG FUSION PROTEIN 3 IZUMO SPERM-EGG FUSION PROTEIN 3 MONDO|Ensembl=ENSMODG00000014779.3|UniProtKB=F7G6Y2 F7G6Y2 ODC1 PTHR11482:SF42 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;ornithine decarboxylase activity#GO:0004586 polyamine metabolic process#GO:0006595;cellular process#GO:0009987;metabolic process#GO:0008152;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 CCKR signaling map#P06959>ODC1#G06989;CCKR signaling map#P06959>ODC1#P07221;Ornithine degradation#P02758>Ornithine decarboxylase#P03053 MONDO|Ensembl=ENSMODG00000001386.3|UniProtKB=F7FJ13 F7FJ13 FAM131B PTHR15736:SF9 PROTEIN FAM131B-RELATED PROTEIN FAM131B MONDO|Ensembl=ENSMODG00000009647.4|UniProtKB=F6QT87 F6QT87 MAP3K11 PTHR44329:SF46 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 11 MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556;microtubule-based process#GO:0007017;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;JNK cascade#GO:0007254;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>MAP3K11#P07139;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834 MONDO|Ensembl=ENSMODG00000004354.4|UniProtKB=F6WPZ4 F6WPZ4 MAEA PTHR12170:SF2 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED E3 UBIQUITIN-PROTEIN TRANSFERASE MAEA catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000019098.5|UniProtKB=A0A5F8HEA5 A0A5F8HEA5 SLC4A4 PTHR11453:SF10 ANION EXCHANGE PROTEIN ELECTROGENIC SODIUM BICARBONATE COTRANSPORTER 1 bicarbonate transmembrane transporter activity#GO:0015106;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324 homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological quality#GO:0065008;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;biological regulation#GO:0065007;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003 membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000002563.4|UniProtKB=F7GFB0 F7GFB0 UTP25 PTHR12933:SF0 ORF PROTEIN-RELATED U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG U3 snoRNA binding#GO:0034511;RNA binding#GO:0003723;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;binding#GO:0005488;rRNA binding#GO:0019843 RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000011926.5|UniProtKB=F7DZE3 F7DZE3 PNN PTHR12707:SF0 PINN PININ catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000005094.4|UniProtKB=F6ZEJ6 F6ZEJ6 CAPN2 PTHR10183:SF268 CALPAIN CALPAIN-2 CATALYTIC SUBUNIT catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 MONDO|Ensembl=ENSMODG00000002600.3|UniProtKB=A0A5F8H0F4 A0A5F8H0F4 ZFHX3 PTHR45891:SF4 ZINC FINGER HOMEOBOX PROTEIN ZINC FINGER HOMEOBOX PROTEIN 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000009444.4|UniProtKB=F7FZM7 F7FZM7 SOCS2 PTHR10155:SF7 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 2 cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;response to cytokine#GO:0034097;response to chemical#GO:0042221;negative regulation of response to stimulus#GO:0048585 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956 MONDO|Ensembl=ENSMODG00000019295.3|UniProtKB=F6RZA0 F6RZA0 RAB34 PTHR47977:SF8 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-34 guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 localization#GO:0051179;vacuole organization#GO:0007033;organelle assembly#GO:0070925;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;Golgi to plasma membrane transport#GO:0006893;vesicle fusion#GO:0006906;protein localization to plasma membrane#GO:0072659;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;phagocytosis#GO:0006909;transport#GO:0006810;lytic vacuole organization#GO:0080171;membrane organization#GO:0061024;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;cellular localization#GO:0051641;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;endocytosis#GO:0006897;Golgi to plasma membrane protein transport#GO:0043001;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;phagolysosome assembly#GO:0001845;protein localization to cell periphery#GO:1990778;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;lysosome organization#GO:0007040;cellular process#GO:0009987;establishment of protein localization#GO:0045184 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;Golgi stack#GO:0005795;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;Golgi apparatus subcompartment#GO:0098791;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cytoplasm#GO:0005737 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000019815.4|UniProtKB=F6STH0 F6STH0 LOC100020922 PTHR12411:SF902 CYSTEINE PROTEASE FAMILY C1-RELATED PROCATHEPSIN L catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000011030.4|UniProtKB=A0A5F8GIM2 A0A5F8GIM2 GRID1 PTHR18966:SF108 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, DELTA-1 ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic signaling#GO:0099536 asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;dendrite#GO:0030425;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;neuron spine#GO:0044309;postsynapse#GO:0098794;dendritic spine#GO:0043197;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell junction#GO:0030054;transporter complex#GO:1990351;synaptic membrane#GO:0097060 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010479.4|UniProtKB=F7ESN0 F7ESN0 ALG11 PTHR45919:SF1 GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000018023.3|UniProtKB=F7AJV6 F7AJV6 QRSL1 PTHR11895:SF179 TRANSAMIDASE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;ligase#PC00142 MONDO|Ensembl=ENSMODG00000021214.4|UniProtKB=F6UGJ5 F6UGJ5 AGFG1 PTHR46134:SF1 DRONGO, ISOFORM F ARF-GAP DOMAIN AND FG REPEAT-CONTAINING PROTEIN 1 gamete generation#GO:0007276;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;spermatid differentiation#GO:0048515;intermediate filament-based process#GO:0045103;acrosome assembly#GO:0001675;intermediate filament organization#GO:0045109;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;vesicle organization#GO:0016050;cellular anatomical entity morphogenesis#GO:0032989;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;supramolecular fiber organization#GO:0097435;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;spermatid development#GO:0007286;sexual reproduction#GO:0019953;male gamete generation#GO:0048232;cellular developmental process#GO:0048869;nucleus organization#GO:0006997;spermatogenesis#GO:0007283;developmental process#GO:0032502 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000027916.2|UniProtKB=K7E147 K7E147 LY6D PTHR16982:SF2 LYMPHOCYTE ANTIGEN 6D LYMPHOCYTE ANTIGEN 6D MONDO|Ensembl=ENSMODG00000000164.4|UniProtKB=F6XAA5 F6XAA5 EXD1 PTHR46628:SF1 PIRNA BIOGENESIS PROTEIN EXD1 PIRNA BIOGENESIS PROTEIN EXD1 gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;piRNA processing#GO:0034587 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000024356.1|UniProtKB=F7AI56 F7AI56 LOC100021887 PTHR48002:SF45 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019162.4|UniProtKB=F7BJR8 F7BJR8 LOC100022317 PTHR12015:SF183 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 26-RELATED locomotion#GO:0040011;cell motility#GO:0048870;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;cellular response to stimulus#GO:0051716;cell chemotaxis#GO:0060326;chemotaxis#GO:0006935;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;cell migration#GO:0016477;granulocyte migration#GO:0097530;response to chemical#GO:0042221;taxis#GO:0042330;cellular process#GO:0009987;leukocyte chemotaxis#GO:0030595;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;leukocyte migration#GO:0050900 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000001863.4|UniProtKB=F6SNI6 F6SNI6 LOC100032185 PTHR11431:SF54 FERRITIN FERRITIN iron ion binding#GO:0005506;ferrous iron binding#GO:0008198;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 storage protein#PC00210 MONDO|Ensembl=ENSMODG00000040985.1|UniProtKB=A0A5F8HGX1 A0A5F8HGX1 RAD51AP2 PTHR39229:SF1 MCG1037962 RAD51-ASSOCIATED PROTEIN 2 MONDO|Ensembl=ENSMODG00000010617.4|UniProtKB=F7DPC6 F7DPC6 TBC1D7 PTHR13530:SF3 TBC1 DOMAIN FAMILY MEMBER 7 TBC1 DOMAIN FAMILY MEMBER 7 binding#GO:0005488;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of TOR signaling#GO:0032006;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000050181.1|UniProtKB=A0A5F8HHL6 A0A5F8HHL6 SLC39A9 PTHR16133:SF5 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED ZINC TRANSPORTER ZIP9 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000002665.5|UniProtKB=F7DHV6 F7DHV6 RNF38 PTHR46171:SF1 GH10160P E3 UBIQUITIN-PROTEIN LIGASE RNF38 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000004771.4|UniProtKB=A0A5F8HH17 A0A5F8HH17 LOC100024441 PTHR24377:SF975 IP01015P-RELATED ZINC FINGER PROTEIN 883-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006804.3|UniProtKB=F6PGS6 F6PGS6 RPL30 PTHR11449:SF1 RIBOSOMAL PROTEIN L30 LARGE RIBOSOMAL SUBUNIT PROTEIN EL30 structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000020065.4|UniProtKB=F7F0Y8 F7F0Y8 LOC100024602 PTHR26453:SF192 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016123.3|UniProtKB=F7DSS7 F7DSS7 SPSB3 PTHR12245:SF5 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 3 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000008314.5|UniProtKB=F7FGU7 F7FGU7 LSM11 PTHR21415:SF1 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000018397.5|UniProtKB=F7DVM5 F7DVM5 B4GALNT3 PTHR12369:SF15 CHONDROITIN SYNTHASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE 3 glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000044100.1|UniProtKB=K7DZN4 K7DZN4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000015683.4|UniProtKB=F7E1C9 F7E1C9 IKZF2 PTHR24404:SF33 ZINC FINGER PROTEIN ZINC FINGER PROTEIN HELIOS nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000047408.1|UniProtKB=A0A5F8GU78 A0A5F8GU78 MED21 PTHR13381:SF0 RNA POLYMERASE II HOLOENZYME COMPONENT SRB7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 21 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000004879.4|UniProtKB=F7FRV4 F7FRV4 DQX1 PTHR18934:SF108 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE HOMOLOG DQX1 isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000002391.3|UniProtKB=A0A5F8GF05 A0A5F8GF05 MMACHC PTHR31457:SF2 METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA TYPE C PROTEIN CYANOCOBALAMIN REDUCTASE _ ALKYLCOBALAMIN DEALKYLASE nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;nucleotide binding#GO:0000166;oxidoreductase activity, acting on metal ions#GO:0016722 cellular process#GO:0009987;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000002170.3|UniProtKB=A0A5F8HJL5 A0A5F8HJL5 TMA16 PTHR13349:SF2 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000015140.4|UniProtKB=F7BUJ2 F7BUJ2 IMPDH1 PTHR11911:SF74 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 1 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;organophosphate biosynthetic process#GO:0090407;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 De novo purine biosynthesis#P02738>IMP dehydrogenase#P02895 MONDO|Ensembl=ENSMODG00000028203.2|UniProtKB=K7E1Y2 K7E1Y2 PTHR46890:SF56 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED OS06G0484800 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010864.3|UniProtKB=F7FW88 F7FW88 RNF125 PTHR46016:SF2 ZINC FINGER, RING/FYVE/PHD-TYPE E3 UBIQUITIN-PROTEIN LIGASE RNF125 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000009706.4|UniProtKB=F7DIZ1 F7DIZ1 QSER1 PTHR14709:SF2 GLUTAMINE AND SERINE-RICH PROTEIN 1-RELATED GLUTAMINE AND SERINE-RICH PROTEIN 1 MONDO|Ensembl=ENSMODG00000002880.3|UniProtKB=F7E1Y1 F7E1Y1 PTHR21021:SF16 GAF/PUTATIVE CYTOSKELETAL PROTEIN TIP41-LIKE PROTEIN protein phosphatase regulator activity#GO:0019888;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;phosphatase activator activity#GO:0019211;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;enzyme activator activity#GO:0008047 TOR signaling#GO:0031929;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000006450.4|UniProtKB=F7FH24 F7FH24 PTHR15710:SF21 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF126 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;cellular response to misfolded protein#GO:0071218;response to stimulus#GO:0050896;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;response to topologically incorrect protein#GO:0035966;response to misfolded protein#GO:0051788;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to topologically incorrect protein#GO:0035967 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000025367.2|UniProtKB=F7D0Y8 F7D0Y8 PTHR10489:SF951 CELL ADHESION MOLECULE RELAXIN-3 RECEPTOR 2 cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;locomotion#GO:0040011;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;chemotaxis#GO:0006935;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000048975.1|UniProtKB=A0A5F8HGN1 A0A5F8HGN1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000048612.1|UniProtKB=A0A5F8GUS0 A0A5F8GUS0 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000013804.3|UniProtKB=F6SY88 F6SY88 PTHR11711:SF422 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 3 ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf1#P00923 MONDO|Ensembl=ENSMODG00000019240.4|UniProtKB=A0A5F8HD50 A0A5F8HD50 LOC100028211 PTHR11941:SF12 ENOYL-COA HYDRATASE-RELATED METHYLGLUTACONYL-COA HYDRATASE, MITOCHONDRIAL catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 hydratase#PC00120;lyase#PC00144;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000013652.5|UniProtKB=F6UD32 F6UD32 BRPF3 PTHR13793:SF19 PHD FINGER PROTEINS BROMODOMAIN AND PHD FINGER-CONTAINING PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000012165.4|UniProtKB=A0A5F8HAJ1 A0A5F8HAJ1 CERS3 PTHR12560:SF18 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 3 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;ceramide metabolic process#GO:0006672 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000025187.2|UniProtKB=F7C1G9 F7C1G9 SPACA4 PTHR47613:SF1 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 4 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 4 sperm-egg recognition#GO:0035036;sexual reproduction#GO:0019953;cell recognition#GO:0008037;cell-cell recognition#GO:0009988;single fertilization#GO:0007338;cellular process#GO:0009987;fertilization#GO:0009566;reproductive process#GO:0022414 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000025412.3|UniProtKB=F7EPN1 F7EPN1 LIPM PTHR11005:SF12 LYSOSOMAL ACID LIPASE-RELATED LIPASE MEMBER M hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 hydrolase#PC00121;lipase#PC00143 MONDO|Ensembl=ENSMODG00000013866.4|UniProtKB=F6WPC0 F6WPC0 NCOA5 PTHR23295:SF3 NUCLEAR RECEPTOR COACTIVATOR 5-RELATED NUCLEAR RECEPTOR COACTIVATOR 5 regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000021127.5|UniProtKB=A0A5F8HHI1 A0A5F8HHI1 TAB3 PTHR46253:SF3 TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN TAB TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 3 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 MONDO|Ensembl=ENSMODG00000044876.1|UniProtKB=A0A5F8GF66 A0A5F8GF66 PTHR21569:SF16 RIBOSOMAL PROTEIN S9 SMALL RIBOSOMAL SUBUNIT PROTEIN US9 binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000012951.4|UniProtKB=F7DWN3 F7DWN3 BMP4 PTHR11848:SF165 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 4 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;response to stimulus#GO:0050896;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;animal organ development#GO:0048513;multicellular organism development#GO:0007275;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;heart morphogenesis#GO:0003007;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;response to growth factor#GO:0070848;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP2/4/15#P06817;TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000014626.3|UniProtKB=F6YPV0 F6YPV0 PTHR23411:SF39 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 1-RELATED antigen binding#GO:0003823;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 response to bacterium#GO:0009617;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;defense response#GO:0006952;response to external stimulus#GO:0009605;immune response#GO:0006955;complement activation#GO:0006956;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;adaptive immune response#GO:0002250;biological regulation#GO:0065007;immune system process#GO:0002376;defense response to bacterium#GO:0042742;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;immune effector process#GO:0002252;antibacterial humoral response#GO:0019731;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;activation of immune response#GO:0002253;defense response to other organism#GO:0098542 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000002668.4|UniProtKB=F7DHT9 F7DHT9 PGD PTHR11811:SF25 6-PHOSPHOGLUCONATE DEHYDROGENASE 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;phosphogluconate dehydrogenase (decarboxylating) activity#GO:0004616;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488 pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;pentose-phosphate shunt#GO:0006098;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;generation of precursor metabolites and energy#GO:0006091;pentose-phosphate shunt, oxidative branch#GO:0009051;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nucleobase-containing compound metabolic process#GO:0006139 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 Pentose phosphate pathway#P02762>Gluconate Dehydrogenase#P03070 MONDO|Ensembl=ENSMODG00000040908.1|UniProtKB=A0A5F8H458 A0A5F8H458 PTHR10621:SF13 UV EXCISION REPAIR PROTEIN RAD23 LYSINE-SPECIFIC DEMETHYLASE RAD23B protein-containing complex binding#GO:0044877;protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 cytosol#GO:0005829;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000049970.1|UniProtKB=A0A5F8H0C6 A0A5F8H0C6 LOC100619014 PTHR23262:SF50 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-8 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000049449.1|UniProtKB=F6Q1U5 F6Q1U5 PTHR26450:SF194 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52N4 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007213.3|UniProtKB=A0A5F8GND0 A0A5F8GND0 PTHR11905:SF232 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 20 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000009708.4|UniProtKB=F6XTN5 F6XTN5 CDX1 PTHR24332:SF16 HOMEOBOX PROTEIN CDX HOMEOBOX PROTEIN CDX-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;animal gross anatomical part developmental process#GO:0160108;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;anterior/posterior axis specification#GO:0009948;developmental process#GO:0032502;anterior/posterior pattern specification#GO:0009952;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;tube development#GO:0035295;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;embryonic pattern specification#GO:0009880;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000047425.1|UniProtKB=A0A5F8H5V5 A0A5F8H5V5 MAFK PTHR10129:SF26 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFK transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 MONDO|Ensembl=ENSMODG00000014284.3|UniProtKB=F6X0K8 F6X0K8 TMEM18 PTHR22593:SF2 TRANSMEMBRANE PROTEIN 18 TRANSMEMBRANE PROTEIN 18 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane#GO:0016020;organelle envelope#GO:0031967;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;nuclear membrane#GO:0031965;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000001182.4|UniProtKB=F7GHC4 F7GHC4 INPP4A PTHR12187:SF4 AGAP000124-PA INOSITOL POLYPHOSPHATE-4-PHOSPHATASE TYPE I A phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 cell junction#GO:0030054;postsynaptic density#GO:0014069;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;organelle#GO:0043226;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;postsynapse#GO:0098794;membrane#GO:0016020 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000011306.3|UniProtKB=F6WYU4 F6WYU4 HBE1 PTHR11442:SF7 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT BETA-RELATED tetrapyrrole binding#GO:0046906;heme binding#GO:0020037;molecular carrier activity#GO:0140104;binding#GO:0005488 cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;homeostatic process#GO:0042592;cell development#GO:0048468;localization#GO:0051179;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871;developmental process#GO:0032502;transport#GO:0006810 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 globin#PC00107;transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000017252.4|UniProtKB=F6TK55 F6TK55 ZC2HC1B PTHR13555:SF36 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1B C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000047367.1|UniProtKB=F6V6L9 F6V6L9 LOC100018962 PTHR48002:SF63 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000042166.1|UniProtKB=F6WNI1 F6WNI1 PTHR21297:SF0 DNA-DIRECTED RNA POLYMERASE II DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 binding#GO:0005488;translation initiation factor binding#GO:0031369;protein binding#GO:0005515 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 MONDO|Ensembl=ENSMODG00000001522.4|UniProtKB=A0A5F8GQB6 A0A5F8GQB6 ASAP1 PTHR45854:SF2 ASAP FAMILY MEMBER ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;positive regulation of cellular component organization#GO:0051130;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;cell periphery#GO:0071944;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;Golgi apparatus#GO:0005794;cytoskeleton#GO:0005856 Integrin signalling pathway#P00034>ASAP1#P00909 MONDO|Ensembl=ENSMODG00000041797.1|UniProtKB=F6VP67 F6VP67 LOC100011711 PTHR19375:SF581 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein refolding#GO:0042026;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072;Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 MONDO|Ensembl=ENSMODG00000042414.1|UniProtKB=A0A5F8HBM1 A0A5F8HBM1 PTHR11449:SF1 RIBOSOMAL PROTEIN L30 LARGE RIBOSOMAL SUBUNIT PROTEIN EL30 binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;RNA binding#GO:0003723 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000037508.1|UniProtKB=A0A5F8H0B4 A0A5F8H0B4 TMEM253 PTHR37359:SF1 TRANSMEMBRANE PROTEIN 253 TRANSMEMBRANE PROTEIN 253 MONDO|Ensembl=ENSMODG00000003393.4|UniProtKB=F6S0Q9 F6S0Q9 SMAD2 PTHR13703:SF42 SMAD SMAD FAMILY MEMBER 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;activin receptor signaling pathway#GO:0032924;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular response to growth factor stimulus#GO:0071363;transforming growth factor beta receptor signaling pathway#GO:0007179;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;intracellular signaling cassette#GO:0141124;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;response to transforming growth factor beta#GO:0071559;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;response to BMP#GO:0071772;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292 MONDO|Ensembl=ENSMODG00000013922.3|UniProtKB=F6SV89 F6SV89 POLM PTHR11276:SF24 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA-DIRECTED DNA_RNA POLYMERASE MU DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA-directed DNA polymerase activity#GO:0003887 response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000005348.3|UniProtKB=A0A5F8HFD5 A0A5F8HFD5 PTHR10137:SF4 V-TYPE PROTON ATPASE SUBUNIT C V-TYPE PROTON ATPASE SUBUNIT C 2 monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;ATPase complex#GO:1904949;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;proton-transporting two-sector ATPase complex#GO:0016469;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000004602.3|UniProtKB=F6Y4G2 F6Y4G2 GRK6 PTHR24355:SF15 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 6 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK6#P05939;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GPRK#P00840 MONDO|Ensembl=ENSMODG00000010827.3|UniProtKB=F7BE53 F7BE53 ATXN1 PTHR13392:SF5 ATAXIN 1 ATAXIN-1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;animal organ development#GO:0048513;negative regulation of macromolecule biosynthetic process#GO:0010558;head development#GO:0060322;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000042774.1|UniProtKB=F6PZ70 F6PZ70 PTHR26450:SF392 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011095.4|UniProtKB=F7DL63 F7DL63 TAF5 PTHR19879:SF4 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;nuclear DNA-directed RNA polymerase complex#GO:0055029;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;transferase complex#GO:1990234;peptidase complex#GO:1905368;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124 MONDO|Ensembl=ENSMODG00000018379.3|UniProtKB=A0A5F8GZ49 A0A5F8GZ49 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000019372.4|UniProtKB=F6WSQ1 F6WSQ1 HOMER2 PTHR10918:SF2 HOMER HOMER PROTEIN HOMOLOG 2 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488 cell surface receptor signaling pathway#GO:0007166;regulation of transport#GO:0051049;system process#GO:0003008;regulation of localization#GO:0032879;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;regulation of monoatomic ion transport#GO:0043269;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;sensory perception of sound#GO:0007605;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;signaling#GO:0023052 cell junction#GO:0030054;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;dendrite#GO:0030425;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794 MONDO|Ensembl=ENSMODG00000007396.3|UniProtKB=F6YZQ3 F6YZQ3 TTC38 PTHR16263:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 38 TETRATRICOPEPTIDE REPEAT PROTEIN 38 MONDO|Ensembl=ENSMODG00000025705.2|UniProtKB=F6TIG0 F6TIG0 PTHR47966:SF24 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED RENIN catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;proteolysis#GO:0006508;circulatory system process#GO:0003013;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;macromolecule metabolic process#GO:0043170;system process#GO:0003008;metabolic process#GO:0008152;hormone metabolic process#GO:0042445;blood circulation#GO:0008015;gene expression#GO:0010467;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;peptide hormone processing#GO:0016486 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 aspartic protease#PC00053;protease#PC00190 MONDO|Ensembl=ENSMODG00000013644.4|UniProtKB=F6UDA5 F6UDA5 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000007647.4|UniProtKB=F6SWS7 F6SWS7 PTHR45716:SF1 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 3 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;transport#GO:0006810;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;exocytosis#GO:0006887;secretion by cell#GO:0032940 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 MONDO|Ensembl=ENSMODG00000047834.1|UniProtKB=A0A5F8GU55 A0A5F8GU55 PTHR48002:SF68 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D10 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002575.2|UniProtKB=A0A5F8GID3 A0A5F8GID3 PTHR45635:SF13 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE 3 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000012113.4|UniProtKB=F7FUC8 F7FUC8 HMG20A PTHR46040:SF1 HIGH MOBILITY GROUP PROTEIN 2 HIGH MOBILITY GROUP PROTEIN 20A regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000015943.4|UniProtKB=F6Z333 F6Z333 TRAF7 PTHR44156:SF31 SUPERNUMERARY LIMBS, ISOFORM B-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRAF7 MONDO|Ensembl=ENSMODG00000049491.1|UniProtKB=A0A5F8H0L8 A0A5F8H0L8 RETN PTHR21101:SF11 RESISTIN RESISTIN molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 response to peptide hormone#GO:0043434;response to stimulus#GO:0050896;response to chemical#GO:0042221;cell differentiation#GO:0030154;response to insulin#GO:0032868;cellular process#GO:0009987;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;fat cell differentiation#GO:0045444;response to nitrogen compound#GO:1901698;cellular developmental process#GO:0048869;response to oxygen-containing compound#GO:1901700;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000019794.4|UniProtKB=F6TA84 F6TA84 RALGPS1 PTHR23113:SF167 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR RALGPS1 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000009388.3|UniProtKB=F7CPI5 F7CPI5 EMX2 PTHR24339:SF25 HOMEOBOX PROTEIN EMX-RELATED HOMEOBOX PROTEIN EMX2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;central nervous system development#GO:0007417;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;nervous system development#GO:0007399;head development#GO:0060322;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;neuron differentiation#GO:0030182;developmental process#GO:0032502;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000014261.3|UniProtKB=F6XIT6 F6XIT6 ETV1 PTHR11849:SF196 ETS ETS TRANSLOCATION VARIANT 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000007926.4|UniProtKB=F7GI63 F7GI63 MBTPS2 PTHR13325:SF3 PROTEASE M50 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE 2 PROTEASE MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-2 PROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 regulation of cellular response to stress#GO:0080135;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;proteolysis#GO:0006508;metabolic process#GO:0008152;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of response to endoplasmic reticulum stress#GO:1905897;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000014406.4|UniProtKB=F7C239 F7C239 ZDHHC18 PTHR22883:SF257 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC18 catalytic activity, acting on a protein#GO:0140096;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;protein targeting#GO:0006605;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000008740.4|UniProtKB=A0A5F8H6J7 A0A5F8H6J7 PRTFDC1 PTHR43340:SF5 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE PHOSPHORIBOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 cation binding#GO:0043169;magnesium ion binding#GO:0000287;metal ion binding#GO:0046872;pentosyltransferase activity#GO:0016763;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase metabolic process#GO:0009112;IMP metabolic process#GO:0046040;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804;Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245;Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247 MONDO|Ensembl=ENSMODG00000018903.4|UniProtKB=F7C7H2 F7C7H2 PTHR14356:SF2 INTERLEUKIN-15-RELATED INTERLEUKIN-21 positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of lymphocyte mediated immunity#GO:0002706;regulation of cell killing#GO:0031341;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;positive regulation of response to external stimulus#GO:0032103;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;positive regulation of natural killer cell mediated immunity#GO:0002717;regulation of response to biotic stimulus#GO:0002831;regulation of natural killer cell mediated immunity#GO:0002715;regulation of leukocyte mediated immunity#GO:0002703;regulation of immune effector process#GO:0002697;positive regulation of biosynthetic process#GO:0009891;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of natural killer cell mediated cytotoxicity#GO:0042269;positive regulation of response to stimulus#GO:0048584;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;regulation of cytokine production#GO:0001817;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778 intercellular signal molecule#PC00207;cytokine#PC00083;interleukin superfamily#PC00128 Interleukin signaling pathway#P00036>Interleukin#P00970 MONDO|Ensembl=ENSMODG00000029263.2|UniProtKB=K7E261 K7E261 VOPP1 PTHR14971:SF2 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 WW DOMAIN BINDING PROTEIN VOPP1 molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;lysosomal membrane#GO:0005765;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;vacuole#GO:0005773;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323 MONDO|Ensembl=ENSMODG00000019884.3|UniProtKB=F6W6D8 F6W6D8 PEX16 PTHR13299:SF0 PEROXISOMAL MEMBRANE PROTEIN PEX16 PEROXISOMAL MEMBRANE PROTEIN PEX16 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;peroxisome organization#GO:0007031 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777 MONDO|Ensembl=ENSMODG00000020981.4|UniProtKB=F6S570 F6S570 KCNJ6 PTHR11767:SF19 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 2 ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741 MONDO|Ensembl=ENSMODG00000025139.3|UniProtKB=F7D5G1 F7D5G1 SH3RF3 PTHR14167:SF62 SH3 DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE SH3RF3 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;protein-macromolecule adaptor activity#GO:0030674;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;molecular adaptor activity#GO:0060090;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;regulation of JNK cascade#GO:0046328;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018766.3|UniProtKB=F7DXP8 F7DXP8 SV2A PTHR23511:SF11 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2A neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;anterograde trans-synaptic signaling#GO:0098916;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;cellular process#GO:0009987;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;exocytic process#GO:0140029;regulated exocytosis#GO:0045055;signaling#GO:0023052;export from cell#GO:0140352;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;secretion by cell#GO:0032940;cellular localization#GO:0051641 cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;presynapse#GO:0098793;neuron projection#GO:0043005;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000040494.1|UniProtKB=A0A5F8GVV0 A0A5F8GVV0 COA7 PTHR13891:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 7 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 7 oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758 MONDO|Ensembl=ENSMODG00000002710.4|UniProtKB=F7CEF4 F7CEF4 CEMIP2 PTHR15535:SF26 TRANSMEMBRANE PROTEIN 2-RELATED CELL SURFACE HYALURONIDASE CEMIP2 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;glycosaminoglycan catabolic process#GO:0006027 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000039059.1|UniProtKB=A0A5F8GKW2 A0A5F8GKW2 CD40LG PTHR11471:SF5 TUMOR NECROSIS FACTOR FAMILY MEMBER CD40 LIGAND signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000018630.3|UniProtKB=F7B2M8 F7B2M8 PTHR24098:SF14 OUTER SEGMENT 5 TRIPARTITE MOTIF-CONTAINING PROTEIN 59 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 cilium#GO:0005929;intraciliary transport particle B#GO:0030992;intraciliary transport particle#GO:0030990;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000023573.2|UniProtKB=F7DBV5 F7DBV5 EIF3J PTHR21681:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of translational initiation#GO:0006446 eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000012965.5|UniProtKB=A0A5F8HJT4 A0A5F8HJT4 BSN PTHR14113:SF1 PICCOLO/BASSOON PROTEIN BASSOON structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 protein localization to cell junction#GO:1902414;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;synapse assembly#GO:0007416;cell junction organization#GO:0034330;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;protein localization to synapse#GO:0035418;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;nervous system development#GO:0007399 cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;GABA-ergic synapse#GO:0098982;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;presynapse#GO:0098793;cell periphery#GO:0071944;glutamatergic synapse#GO:0098978;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;presynaptic active zone#GO:0048786 MONDO|Ensembl=ENSMODG00000009125.4|UniProtKB=A0A5F8H8W9 A0A5F8H8W9 PTHR46766:SF2 GLUTAMINE-RICH PROTEIN 2 GLUTAMINE-RICH PROTEIN 2 cilium-dependent cell motility#GO:0060285;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cell projection organization#GO:0030030;reproductive process#GO:0022414;cellular component organization#GO:0016043;sperm motility#GO:0097722;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;flagellated sperm motility#GO:0030317;cellular component assembly#GO:0022607;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 membrane-bounded organelle#GO:0043227;9+2 motile cilium#GO:0097729;cilium#GO:0005929;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000003340.4|UniProtKB=F7CTY1 F7CTY1 RAB1A PTHR24073:SF963 DRAB5-RELATED RAS-RELATED PROTEIN RAB-1A GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 metabolic process#GO:0008152;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;organelle assembly#GO:0070925;localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;cellular component organization#GO:0016043;catabolic process#GO:0009056 Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell body#GO:0044297;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000002314.5|UniProtKB=F7A3L2 F7A3L2 VAV1 PTHR45818:SF2 PROTEIN VAV PROTO-ONCOGENE VAV nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of immune response#GO:0050776;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of cellular process#GO:0048522;cell migration#GO:0016477;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;small GTPase-mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 B cell activation#P00010>vav#P00368;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GEF#P00875;T cell activation#P00053>vav#P01295;PDGF signaling pathway#P00047>Vav#P01169 MONDO|Ensembl=ENSMODG00000014648.4|UniProtKB=F7EQA1 F7EQA1 NPAT PTHR15087:SF14 PROTEIN NPAT PROTEIN NPAT transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000020888.3|UniProtKB=H9H7Q0 H9H7Q0 RIBC1 PTHR14517:SF11 RIB43A-RELATED RIB43A-LIKE WITH COILED-COILS PROTEIN 1 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000004559.4|UniProtKB=F6R5B7 F6R5B7 CARKD PTHR12592:SF0 ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 MONDO|Ensembl=ENSMODG00000021489.4|UniProtKB=F7G2W0 F7G2W0 ABHD3 PTHR10794:SF50 ABHYDROLASE DOMAIN-CONTAINING PROTEIN PHOSPHOLIPASE ABHD3 A2-type glycerophospholipase activity#GO:0004623;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;hydrolase activity#GO:0016787;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;organophosphate metabolic process#GO:0019637;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;monocarboxylic acid catabolic process#GO:0072329;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058 protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000011830.4|UniProtKB=F7GLV8 F7GLV8 CPNE4 PTHR10857:SF4 COPINE COPINE-4 lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 response to metal ion#GO:0010038;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to chemical stimulus#GO:0070887;response to calcium ion#GO:0051592;response to stimulus#GO:0050896;response to chemical#GO:0042221 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000010614.4|UniProtKB=F7G814 F7G814 PKD2L1 PTHR10877:SF196 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-2-LIKE PROTEIN 1 calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267;cation binding#GO:0043169;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;small molecule binding#GO:0036094;ion binding#GO:0043167;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;monoatomic ion-gated channel activity#GO:0022839;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;calcium-activated potassium channel activity#GO:0015269;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;metal ion binding#GO:0046872;protein binding#GO:0005515;gated channel activity#GO:0022836;calcium ion binding#GO:0005509;binding#GO:0005488;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;cytoskeletal protein binding#GO:0008092 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;detection of stimulus#GO:0051606;cellular process#GO:0009987;response to mechanical stimulus#GO:0009612;establishment of localization#GO:0051234;response to external stimulus#GO:0009605;detection of mechanical stimulus#GO:0050982;transport#GO:0006810;response to stimulus#GO:0050896;metal ion transport#GO:0030001;response to abiotic stimulus#GO:0009628;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000013005.2|UniProtKB=F7C853 F7C853 C3orf62 PTHR36680:SF1 HYPOTHETICAL LOC498675 CHROMOSOME 3 OPEN READING FRAME 62 MONDO|Ensembl=ENSMODG00000000149.4|UniProtKB=A0A5F8GXL8 A0A5F8GXL8 ECD PTHR13060:SF0 SGT1 PROTEIN HSGT1 SUPPRESSOR OF GCR2 PROTEIN ECDYSONELESS HOMOLOG transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000021204.4|UniProtKB=F6UH62 F6UH62 CUL3 PTHR11932:SF180 CULLIN CULLIN-3 protein binding#GO:0005515;structural molecule activity#GO:0005198;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;protein complex scaffold activity#GO:0140378;enzyme binding#GO:0019899 cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000003756.4|UniProtKB=F7AAP1 F7AAP1 CDH12 PTHR24027:SF96 CADHERIN-23 CADHERIN-12 beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 anatomical structure morphogenesis#GO:0009653;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330;cell motility#GO:0048870;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular component assembly#GO:0022607;cell migration#GO:0016477;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840 cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000015722.2|UniProtKB=F7B5Q4 F7B5Q4 ABHD1 PTHR10794:SF60 ABHYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid catabolic process#GO:0072329;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394 protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000008567.3|UniProtKB=A0A5F8GXW6 A0A5F8GXW6 MTMR6 PTHR10807:SF34 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR6 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;dephosphorylation#GO:0016311;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane#GO:0016020 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000010831.4|UniProtKB=A0A5F8GLL1 A0A5F8GLL1 SNX22 PTHR15813:SF8 SORTING NEXIN-22 AND 24 SORTING NEXIN-22 lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;binding#GO:0005488 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014825.2|UniProtKB=F7D1R9 F7D1R9 LOC100013726 PTHR26453:SF712 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10H1-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011883.5|UniProtKB=A0A5F8H645 A0A5F8H645 CHRNA3 PTHR18945:SF831 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-3 monoatomic cation transmembrane transporter activity#GO:0008324;acetylcholine receptor activity#GO:0015464;postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857 localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;modulation of chemical synaptic transmission#GO:0050804;membrane depolarization#GO:0051899;regulation of cell communication#GO:0010646;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;establishment of localization#GO:0051234;transport#GO:0006810;synaptic transmission, cholinergic#GO:0007271;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;neuromuscular synaptic transmission#GO:0007274;response to chemical#GO:0042221;regulation of trans-synaptic signaling#GO:0099177;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane protein complex#GO:0098797;postsynapse#GO:0098794;membrane protein complex#GO:0098796;transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNA3#P06595;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088 MONDO|Ensembl=ENSMODG00000021517.4|UniProtKB=A0A5F8G9M3 A0A5F8G9M3 PTHR24027:SF79 CADHERIN-23 CADHERIN-2 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cell junction organization#GO:0034330;cell motility#GO:0048870;synapse assembly#GO:0007416;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;system development#GO:0048731;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell migration#GO:0016477;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 anchoring junction#GO:0070161;intercalated disc#GO:0014704;intracellular anatomical structure#GO:0005622;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell-cell contact zone#GO:0044291;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cytoplasm#GO:0005737;lamellipodium#GO:0030027;protein-containing complex#GO:0032991 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000006365.3|UniProtKB=F6TN07 F6TN07 LOC100017518 PTHR22652:SF0 NUCLEOPORIN NUP43 NUCLEOPORIN NUP43 intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;nuclear pore outer ring#GO:0031080;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226 transporter#PC00227 MONDO|Ensembl=ENSMODG00000003814.4|UniProtKB=F6YW83 F6YW83 USP24 PTHR24006:SF729 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 24 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000019741.4|UniProtKB=F6WNU9 F6WNU9 NEK6 PTHR43289:SF13 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED SERINE_THREONINE-PROTEIN KINASE NEK6 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of chromosome organization#GO:0033044;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular component organization#GO:0051128;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle phase transition#GO:1901990 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000045534.1|UniProtKB=A0A5F8GV80 A0A5F8GV80 PTHR44427:SF13 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 4-RELATED cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000021514.4|UniProtKB=F7FSF9 F7FSF9 AQP4 PTHR19139:SF34 AQUAPORIN TRANSPORTER AQUAPORIN-4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 fluid transport#GO:0042044;establishment of localization#GO:0051234;localization#GO:0051179;water transport#GO:0006833;transport#GO:0006810 membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000012833.4|UniProtKB=F7DCK8 F7DCK8 NR5A2 PTHR24086:SF18 NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A MEMBER 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;hormone-mediated signaling pathway#GO:0009755;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;tissue development#GO:0009888;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000013361.4|UniProtKB=F7DTU7 F7DTU7 AMN PTHR14995:SF2 AMNIONLESS PROTEIN AMNIONLESS multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;macromolecule localization#GO:0033036;cellular process#GO:0009987;renal system process#GO:0003014;renal absorption#GO:0070293;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;system process#GO:0003008;intracellular protein localization#GO:0008104;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810 apical part of cell#GO:0045177;signaling receptor complex#GO:0043235;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000009220.4|UniProtKB=A0A5F8GX49 A0A5F8GX49 KATNAL1 PTHR23074:SF65 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 1 hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;macromolecular conformation isomerase activity#GO:0120543 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000016699.3|UniProtKB=F7D2H5 F7D2H5 MTG2 PTHR11702:SF31 DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2 ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000043195.1|UniProtKB=A0A5F8GQL8 A0A5F8GQL8 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015721.3|UniProtKB=F7B5S1 F7B5S1 KCTD13 PTHR11145:SF18 BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER BTB_POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 1 protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;regulation of Rho protein signal transduction#GO:0035023;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of small GTPase mediated signal transduction#GO:0051056;cellular process#GO:0009987;protein ubiquitination#GO:0016567;negative regulation of signal transduction#GO:0009968;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;post-translational protein modification#GO:0043687 intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;Cul3-RING ubiquitin ligase complex#GO:0031463;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005067.4|UniProtKB=F7ASI1 F7ASI1 TNFSF13B PTHR15151:SF2 PROTEIN EIGER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125 regulation of cell population proliferation#GO:0042127;positive regulation of lymphocyte activation#GO:0051251;homeostasis of number of cells#GO:0048872;positive regulation of lymphocyte proliferation#GO:0050671;positive regulation of B cell proliferation#GO:0030890;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;multicellular organismal-level homeostasis#GO:0048871;positive regulation of leukocyte proliferation#GO:0070665;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of lymphocyte proliferation#GO:0050670;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;immune system process#GO:0002376;regulation of lymphocyte activation#GO:0051249;response to stimulus#GO:0050896;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694;positive regulation of cell population proliferation#GO:0008284;positive regulation of mononuclear cell proliferation#GO:0032946;regulation of leukocyte proliferation#GO:0070663;positive regulation of leukocyte activation#GO:0002696;regulation of B cell proliferation#GO:0030888;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;regulation of B cell activation#GO:0050864;positive regulation of immune system process#GO:0002684;lymphocyte homeostasis#GO:0002260;regulation of mononuclear cell proliferation#GO:0032944 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000003187.4|UniProtKB=F6VGW0 F6VGW0 LOC100020693 PTHR42985:SF10 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 1 solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;fatty acid transport#GO:0015908;monocarboxylic acid transport#GO:0015718;monoatomic ion transport#GO:0006811;lipid localization#GO:0010876;lipid transport#GO:0006869;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization#GO:0051234;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000045886.1|UniProtKB=K7E185 K7E185 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000007268.4|UniProtKB=A0A5F8HFU5 A0A5F8HFU5 ESRP1 PTHR13976:SF37 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED EPITHELIAL SPLICING REGULATORY PROTEIN 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000004608.4|UniProtKB=F6Y3Q3 F6Y3Q3 PTHR11920:SF458 GUANYLYL CYCLASE GUANYLATE CYCLASE lyase activity#GO:0016829;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383;peptide receptor activity#GO:0001653;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;cyclic nucleotide biosynthetic process#GO:0009190 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 lyase#PC00144;guanylate cyclase#PC00114 MONDO|Ensembl=ENSMODG00000011022.4|UniProtKB=F7FVE0 F7FVE0 LOC100019583 PTHR14224:SF9 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 14 MONDO|Ensembl=ENSMODG00000016905.3|UniProtKB=F6XIA1 F6XIA1 SOX8 PTHR45803:SF2 SOX100B TRANSCRIPTION FACTOR SOX-8 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;animal gross anatomical part developmental process#GO:0160108;negative regulation of metabolic process#GO:0009892;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519;peripheral nervous system development#GO:0007422;morphogenesis of an epithelium#GO:0002009;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neural crest cell differentiation#GO:0014033;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;mesenchymal cell differentiation#GO:0048762;nervous system development#GO:0007399;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;stem cell development#GO:0048864;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;mesenchyme development#GO:0060485;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;multicellular organismal process#GO:0032501;neural crest cell development#GO:0014032;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;stem cell differentiation#GO:0048863;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 MONDO|Ensembl=ENSMODG00000012442.2|UniProtKB=F6PJF8 F6PJF8 LOC100009993 PTHR26453:SF23 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13C9 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045200.1|UniProtKB=A0A5F8HH82 A0A5F8HH82 LOC100012347 PTHR26453:SF116 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2F1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037161.1|UniProtKB=F6UIY1 F6UIY1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024017.3|UniProtKB=F6YP13 F6YP13 P2RY6 PTHR24231:SF16 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 6 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000049910.1|UniProtKB=A0A5F8HG87 A0A5F8HG87 PTHR10438:SF18 THIOREDOXIN THIOREDOXIN catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036 homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Hypoxia response via HIF activation#P00030>Thioredoxin#P00825;Oxidative stress response#P00046>TRX#P01122 MONDO|Ensembl=ENSMODG00000010849.4|UniProtKB=F7ARG7 F7ARG7 PTHR11844:SF20 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 1 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 response to hormone#GO:0009725;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of protein catabolic process#GO:0042177;response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162;regulation of catabolic process#GO:0009894;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of protein catabolic process#GO:0042176;response to peptide#GO:1901652;negative regulation of catabolic process#GO:0009895 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000037867.1|UniProtKB=F7F0Z7 F7F0Z7 monDomV1R1226 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014802.3|UniProtKB=F7DMF4 F7DMF4 GHDC PTHR31901:SF9 GH3 DOMAIN-CONTAINING PROTEIN GH3 DOMAIN-CONTAINING PROTEIN ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000044348.1|UniProtKB=F6Q311 F6Q311 LOC100618838 PTHR26450:SF40 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56A3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019598.2|UniProtKB=A0A5F8GYJ2 A0A5F8GYJ2 PTHR12682:SF11 ARCHEASE TRNA-SPLICING LIGASE-ACTIVATING FACTOR ARCHEASE catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 MONDO|Ensembl=ENSMODG00000000994.5|UniProtKB=F7EA80 F7EA80 TNRC18 PTHR12505:SF21 PHD FINGER TRANSCRIPTION FACTOR TRINUCLEOTIDE REPEAT-CONTAINING GENE 18 PROTEIN DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000003391.4|UniProtKB=A0A5F8GJD5 A0A5F8GJD5 ZBTB17 PTHR24399:SF8 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 17 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of multicellular organismal process#GO:0051239;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000051427.1|UniProtKB=A0A5F8GS91 A0A5F8GS91 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000029714.2|UniProtKB=K7E679 K7E679 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009074.3|UniProtKB=F7FQZ7 F7FQZ7 CCDC85B PTHR13546:SF12 RE60986P COILED-COIL DOMAIN-CONTAINING PROTEIN 85B negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000040024.1|UniProtKB=K7E386 K7E386 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000016572.4|UniProtKB=F6QGC5 F6QGC5 PTHR11937:SF572 ACTIN ACTIN ALPHA 1, SKELETAL MUSCLE A ISOFORM X1 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Cadherin signaling pathway#P00012>F-actin#P00470;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Huntington disease#P00029>Actin#P00807 MONDO|Ensembl=ENSMODG00000011542.3|UniProtKB=F6QWW8 F6QWW8 PLP1 PTHR11683:SF11 MYELIN PROTEOLIPID MYELIN PROTEOLIPID PROTEIN structural molecule activity#GO:0005198 oligodendrocyte differentiation#GO:0048709;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;axon development#GO:0061564;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;gliogenesis#GO:0042063;neurogenesis#GO:0022008;myelination#GO:0042552;neuron differentiation#GO:0030182;developmental process#GO:0032502;central nervous system development#GO:0007417;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;myelin sheath#GO:0043209 myelin protein#PC00161 MONDO|Ensembl=ENSMODG00000044517.1|UniProtKB=A0A5F8HBJ9 A0A5F8HBJ9 BATF3 PTHR23351:SF13 FOS TRANSCRIPTION FACTOR-RELATED BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 MONDO|Ensembl=ENSMODG00000000560.4|UniProtKB=F6X525 F6X525 GBA3 PTHR10353:SF291 GLYCOSYL HYDROLASE CYTOSOLIC BETA-GLUCOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;glucosidase activity#GO:0015926;beta-glucosidase activity#GO:0008422;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 ceramide metabolic process#GO:0006672;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;catabolic process#GO:0009056;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 glycosidase#PC00110;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000007472.4|UniProtKB=F6SGM8 F6SGM8 SWT1 PTHR16161:SF0 TRANSCRIPTIONAL PROTEIN SWT1 TRANSCRIPTIONAL PROTEIN SWT1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521 negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;nuclear mRNA surveillance#GO:0071028;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000004563.4|UniProtKB=F6R560 F6R560 PDXDC1 PTHR42735:SF1 FAMILY NOT NAMED PYRIDOXAL-DEPENDENT DECARBOXYLASE DOMAIN-CONTAINING PROTEIN 1-RELATED catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832 sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid catabolic process#GO:0016042;catabolic process#GO:0009056 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000050976.1|UniProtKB=F7EM99 F7EM99 LOC100020762 PTHR26450:SF38 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR FAMILY 52 SUBFAMILY S MEMBER 6 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004254.3|UniProtKB=A0A5F8G6W5 A0A5F8G6W5 PTHR19300:SF45 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 5 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378 liposaccharide metabolic process#GO:1903509;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000001690.3|UniProtKB=F6S7Q9 F6S7Q9 TDO2 PTHR10138:SF0 TRYPTOPHAN 2,3-DIOXYGENASE TRYPTOPHAN 2,3-DIOXYGENASE binding#GO:0005488;catalytic activity#GO:0003824;heme binding#GO:0020037;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;tetrapyrrole binding#GO:0046906;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520 oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000005737.3|UniProtKB=F6QEB5 F6QEB5 PMM2 PTHR10466:SF2 PHOSPHOMANNOMUTASE PHOSPHOMANNOMUTASE 2 intramolecular phosphotransferase activity#GO:0016868;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;isomerase activity#GO:0016853 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;hexose metabolic process#GO:0019318;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 mutase#PC00160;isomerase#PC00135;metabolite interconversion enzyme#PC00262 Mannose metabolism#P02752>P-Mannose mutase#P03019 MONDO|Ensembl=ENSMODG00000046231.1|UniProtKB=A0A5F8GF83 A0A5F8GF83 PTHR19971:SF24 SIGNAL-REGULATORY PROTEIN BETA IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000044610.1|UniProtKB=A0A5F8GY19 A0A5F8GY19 TMED1 PTHR22811:SF40 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 1 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;macromolecule localization#GO:0033036;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;Golgi organization#GO:0007030;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000045667.1|UniProtKB=A0A5F8H4N6 A0A5F8H4N6 LOC100618432 PTHR26450:SF351 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028729.2|UniProtKB=K7E479 K7E479 TINAGL1 PTHR12411:SF270 CYSTEINE PROTEASE FAMILY C1-RELATED TUBULOINTERSTITIAL NEPHRITIS ANTIGEN-LIKE catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000002847.4|UniProtKB=F7B627 F7B627 LRP1B PTHR22722:SF5 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1B hormone binding#GO:0042562;binding#GO:0005488 import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987 apical part of cell#GO:0045177;signaling receptor complex#GO:0043235;apical plasma membrane#GO:0016324;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112 MONDO|Ensembl=ENSMODG00000015302.4|UniProtKB=F6QD19 F6QD19 ATG9A PTHR13038:SF13 APG9 AUTOPHAGY 9 AUTOPHAGY-RELATED PROTEIN 9A phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303 reticulophagy#GO:0061709;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;autophagosome assembly#GO:0000045;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;organelle assembly#GO:0070925;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033 vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000021306.5|UniProtKB=F7G3I2 F7G3I2 ZNF639 PTHR24404:SF35 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 639 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002480.3|UniProtKB=F7BVX3 F7BVX3 DHODH PTHR48109:SF4 DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;pyrimidine nucleobase metabolic process#GO:0006206;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Dihydrooratate oxidase#P02927 MONDO|Ensembl=ENSMODG00000004926.4|UniProtKB=F7BGF0 F7BGF0 NUDCD1 PTHR21664:SF1 CHRONIC MYELOGENOUS LEUKEMIA TUMOR ANTIGEN 66 NUDC DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000041019.1|UniProtKB=F6S991 F6S991 LOC100618735 PTHR48002:SF60 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027448.2|UniProtKB=K7E2C3 K7E2C3 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000015021.4|UniProtKB=F7BXG3 F7BXG3 HAUS8 PTHR31807:SF37 AUGMIN FAMILY MEMBER HAUS AUGMIN-LIKE COMPLEX SUBUNIT 8 MONDO|Ensembl=ENSMODG00000006431.4|UniProtKB=A0A5F8G7R6 A0A5F8G7R6 EXOC6 PTHR12702:SF2 SEC15 EXOCYST COMPLEX COMPONENT 6 export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;exocytosis#GO:0006887;secretion by cell#GO:0032940;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;transport#GO:0006810 exocyst#GO:0000145;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000027714.2|UniProtKB=K7E0Q4 K7E0Q4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000039845.1|UniProtKB=F7D8P9 F7D8P9 TTC4 PTHR46035:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 4 HSP70_HSP90 CO-CHAPERONE CNS1 HOMOLOG protein binding#GO:0005515;Hsp70 protein binding#GO:0030544;binding#GO:0005488;protein-folding chaperone binding#GO:0051087;Hsp90 protein binding#GO:0051879;heat shock protein binding#GO:0031072 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000014561.4|UniProtKB=F7E8K6 F7E8K6 SSMEM1 PTHR31822:SF1 SERINE-RICH SINGLE-PASS MEMBRANE PROTEIN 1 SERINE-RICH SINGLE-PASS MEMBRANE PROTEIN 1 MONDO|Ensembl=ENSMODG00000011540.4|UniProtKB=A0A5F8H6V8 A0A5F8H6V8 ADAMTS7 PTHR13723:SF142 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 7 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;external encapsulating structure organization#GO:0045229;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000042873.1|UniProtKB=A0A5F8GEA5 A0A5F8GEA5 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000040559.1|UniProtKB=A0A5F8H583 A0A5F8H583 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003864.3|UniProtKB=F7DTS2 F7DTS2 TTC22 PTHR16253:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 22 TETRATRICOPEPTIDE REPEAT PROTEIN 22 MONDO|Ensembl=ENSMODG00000050984.1|UniProtKB=K7E3K5 K7E3K5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003942.4|UniProtKB=F7G9G4 F7G9G4 MORN4 PTHR46614:SF1 MORN REPEAT-CONTAINING PROTEIN 4 MORN REPEAT-CONTAINING PROTEIN 4 response to stimulus#GO:0050896;response to stress#GO:0006950;response to wounding#GO:0009611 cell projection#GO:0042995;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000016305.3|UniProtKB=F7ATC1 F7ATC1 AQP8 PTHR45665:SF66 AQUAPORIN-8 AQUAPORIN-8 water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 transport#GO:0006810;localization#GO:0051179;water transport#GO:0006833;establishment of localization#GO:0051234;fluid transport#GO:0042044 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000046783.1|UniProtKB=A0A5F8GVU9 A0A5F8GVU9 LOC100022644 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016703.4|UniProtKB=F7D2D8 F7D2D8 NTRK1 PTHR24416:SF370 TYROSINE-PROTEIN KINASE RECEPTOR HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;transferase activity#GO:0016740;kinase activity#GO:0016301;signaling receptor activity#GO:0038023 signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cell differentiation#GO:0030154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;generation of neurons#GO:0048699;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cellular response to nerve growth factor stimulus#GO:1990090;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182 axon#GO:0030424;signaling receptor complex#GO:0043235;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000039206.1|UniProtKB=F7BE89 F7BE89 RAB21 PTHR24070:SF447 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAB-21 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000012492.4|UniProtKB=A0A5F8HDH4 A0A5F8HDH4 RAPGEF1 PTHR23113:SF224 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;positive regulation of neuron projection development#GO:0010976;Ras protein signal transduction#GO:0007265;positive regulation of cell projection organization#GO:0031346;positive regulation of cellular component organization#GO:0051130;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 Integrin signalling pathway#P00034>C3G#P00929 MONDO|Ensembl=ENSMODG00000027691.1|UniProtKB=K7E0I9 K7E0I9 PTHR10424:SF72 VIRAL ENVELOPE PROTEIN BC035947 PROTEIN-RELATED cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;syncytium formation by cell-cell fusion#GO:0000768;striated muscle cell differentiation#GO:0051146;animal gross anatomical part developmental process#GO:0160108;cell-cell fusion#GO:0140253;developmental process#GO:0032502;muscle structure development#GO:0061061;cell differentiation#GO:0030154;myoblast fusion#GO:0007520;cellular process#GO:0009987;muscle cell differentiation#GO:0042692 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000023207.1|UniProtKB=F7CM88 F7CM88 MLLT11 PTHR15404:SF2 PROTEIN AF1Q PROTEIN AF1Q regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of release of cytochrome c from mitochondria#GO:0090199;positive regulation of cellular component organization#GO:0051130;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of organelle organization#GO:0010638;regulation of DNA-templated transcription#GO:0006355;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of membrane potential#GO:0042391;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;cytosol#GO:0005829;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000027882.2|UniProtKB=K7E038 K7E038 PTHR16021:SF7 MANSC DOMAIN CONTAINING PROTEIN 1 MANSC DOMAIN-CONTAINING PROTEIN 1 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000008975.3|UniProtKB=F7FRM9 F7FRM9 PTHR33517:SF6 PROTEIN FAM170B-RELATED FAMILY WITH SEQUENCE SIMILARITY 170 MEMBER B fertilization#GO:0009566;reproductive process#GO:0022414;sexual reproduction#GO:0019953 MONDO|Ensembl=ENSMODG00000025238.2|UniProtKB=F7F647 F7F647 LOC100618026 PTHR26454:SF18 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C76 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011268.3|UniProtKB=F6X011 F6X011 TACR1 PTHR46925:SF4 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED SUBSTANCE-P RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145;regulation of microtubule-based process#GO:0032886;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of reproductive process#GO:2000241;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cell motility#GO:2000147 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cilium#GO:0005929;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227 G-protein coupled receptor#PC00021 CCKR signaling map#P06959>TACR1#G07279;CCKR signaling map#P06959>TACR1#G06985 MONDO|Ensembl=ENSMODG00000004705.4|UniProtKB=F6TQ40 F6TQ40 TAF1A PTHR32122:SF1 TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT A TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT A General transcription by RNA polymerase I#P00022>TAF-IA#P00651;General transcription by RNA polymerase I#P00022>SL1 complex#P00653 MONDO|Ensembl=ENSMODG00000016112.4|UniProtKB=F7EAV9 F7EAV9 PHYHIPL PTHR15698:SF8 PROTEIN CBG15099 PHYTANOYL-COA HYDROXYLASE-INTERACTING PROTEIN-LIKE cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000047647.1|UniProtKB=A0A5F8GR74 A0A5F8GR74 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010910.4|UniProtKB=F7A0V4 F7A0V4 WASHC2C PTHR21669:SF38 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS WASH COMPLEX SUBUNIT 2A-RELATED phosphatidylinositol phosphate binding#GO:1901981;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 protein localization to organelle#GO:0033365;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006602.3|UniProtKB=F7AK18 F7AK18 FAM161B PTHR21501:SF4 PROTEIN FAM-161 PROTEIN FAM161B organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782 MONDO|Ensembl=ENSMODG00000011200.3|UniProtKB=F6SQY9 F6SQY9 NAGK PTHR12862:SF0 BADF TYPE ATPASE DOMAIN-CONTAINING PROTEIN N-ACETYL-D-GLUCOSAMINE KINASE carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 MONDO|Ensembl=ENSMODG00000004990.3|UniProtKB=A0A5F8H5T2 A0A5F8H5T2 MBTPS1 PTHR43806:SF7 PEPTIDASE S8 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-1 PROTEASE catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000001627.4|UniProtKB=F7AMY3 F7AMY3 CFAP119 PTHR28457:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 119 MONDO|Ensembl=ENSMODG00000017087.4|UniProtKB=A0A5F8HKG7 A0A5F8HKG7 PTHR11955:SF61 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, HEART organic acid binding#GO:0043177;binding#GO:0005488;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;ion binding#GO:0043167;lipid binding#GO:0008289;fatty acid binding#GO:0005504 macromolecule localization#GO:0033036;lipid transport#GO:0006869;lipid localization#GO:0010876;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;establishment of localization#GO:0051234;fatty acid transport#GO:0015908;localization#GO:0051179;monocarboxylic acid transport#GO:0015718 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000008679.4|UniProtKB=F6PFT3 F6PFT3 EWSR1 PTHR23238:SF3 RNA BINDING PROTEIN RNA-BINDING PROTEIN EWS RNA binding#GO:0003723;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000008877.4|UniProtKB=A0A5F8GZH5 A0A5F8GZH5 XYLB PTHR10196:SF57 SUGAR KINASE XYLULOSE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;monosaccharide metabolic process#GO:0005996;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065;kinase#PC00137 Ascorbate degradation#P02729>L-xylulose kinase#P02849 MONDO|Ensembl=ENSMODG00000044944.1|UniProtKB=A0A5F8HBH5 A0A5F8HBH5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000005353.4|UniProtKB=F6YLI5 F6YLI5 TBR1 PTHR11267:SF88 T-BOX PROTEIN-RELATED T-BOX BRAIN PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 cell fate commitment#GO:0045165;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;forebrain development#GO:0030900;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;cell fate specification#GO:0001708;head development#GO:0060322;nervous system development#GO:0007399;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;regulation of cell projection organization#GO:0031344;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;neuron fate commitment#GO:0048663;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 MONDO|Ensembl=ENSMODG00000013747.3|UniProtKB=F6X7L4 F6X7L4 CLPS PTHR10041:SF9 COLIPASE COLIPASE enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000023650.3|UniProtKB=F6WZD2 F6WZD2 PTHR24376:SF85 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 600-RELATED regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000041663.1|UniProtKB=A0A5F8GAV3 A0A5F8GAV3 ANKRD39 PTHR24180:SF45 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED ANKYRIN REPEAT DOMAIN 39 kinase inhibitor#PC00139;kinase modulator#PC00140 MONDO|Ensembl=ENSMODG00000003459.3|UniProtKB=F7DCD4 F7DCD4 ZNF622 PTHR13182:SF8 ZINC FINGER PROTEIN 622 CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622 protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000003931.4|UniProtKB=F7GIX1 F7GIX1 PI4K2A PTHR12865:SF7 PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-ALPHA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity#GO:0016740;catalytic activity#GO:0003824 organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;Golgi organization#GO:0007030;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;endosome organization#GO:0007032;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;endomembrane system organization#GO:0010256;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;organelle organization#GO:0006996 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;plasma membrane#GO:0005886;endomembrane system#GO:0012505 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000002426.2|UniProtKB=F7E0F9 F7E0F9 LOC100013919 PTHR21737:SF3 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 POLYGLUTAMINE-BINDING PROTEIN 1 protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cytoplasm#GO:0005737;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020335.4|UniProtKB=F7FWW7 F7FWW7 WDR70 PTHR16017:SF0 GASTRULATION DEFECTIVE PROTEIN 1-RELATED WD REPEAT-CONTAINING PROTEIN 70 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694;site of double-strand break#GO:0035861;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000043520.1|UniProtKB=F7A727 F7A727 VN2R510 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000011270.4|UniProtKB=A0A5F8HDS1 A0A5F8HDS1 KDM1B PTHR10742:SF410 FLAVIN MONOAMINE OXIDASE LYSINE-SPECIFIC HISTONE DEMETHYLASE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175 MONDO|Ensembl=ENSMODG00000025674.3|UniProtKB=F6U0X7 F6U0X7 PTHR15343:SF0 CD7 T-CELL ANTIGEN CD7 MONDO|Ensembl=ENSMODG00000007675.4|UniProtKB=F7FNH0 F7FNH0 RAD9A PTHR15237:SF1 DNA REPAIR PROTEIN RAD9 CELL CYCLE CHECKPOINT CONTROL PROTEIN RAD9A regulation of cell cycle#GO:0051726;signaling#GO:0023052;cellular response to radiation#GO:0071478;response to stimulus#GO:0050896;response to ionizing radiation#GO:0010212;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;response to abiotic stimulus#GO:0009628;negative regulation of mitotic cell cycle#GO:0045930;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cellular response to stress#GO:0033554;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle#GO:0045786;cellular response to abiotic stimulus#GO:0071214;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;response to radiation#GO:0009314;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA integrity checkpoint signaling#GO:0031570;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523 nuclear protein-containing complex#GO:0140513;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;chromosome#GO:0005694 exodeoxyribonuclease#PC00098 MONDO|Ensembl=ENSMODG00000017885.4|UniProtKB=F7GFM4 F7GFM4 CAPZA3 PTHR10653:SF6 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of actin filament depolymerization#GO:0030834;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex assembly#GO:0031333;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of protein depolymerization#GO:1901879;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cell periphery#GO:0071944;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000024618.3|UniProtKB=F6PPC2 F6PPC2 TMEM170B PTHR22779:SF4 SD17342P TRANSMEMBRANE PROTEIN 170B negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000014887.2|UniProtKB=A0A5F8H3I9 A0A5F8H3I9 PTHR12317:SF74 DIACYLGLYCEROL O-ACYLTRANSFERASE 2-ACYLGLYCEROL O-ACYLTRANSFERASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;neutral lipid metabolic process#GO:0006638;primary metabolic process#GO:0044238;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 acyltransferase#PC00042;transferase#PC00220 MONDO|Ensembl=ENSMODG00000047074.1|UniProtKB=H9H998 H9H998 LOC100616767 PTHR26454:SF59 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002109.3|UniProtKB=F6UGS6 F6UGS6 TNFAIP8L3 PTHR12757:SF5 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8-LIKE PROTEIN 3 phosphatidylinositol transfer activity#GO:0008526;lipid transfer activity#GO:0120013;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;organophosphate ester transport#GO:0015748;regulation of biological process#GO:0050789;localization#GO:0051179;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;lipid localization#GO:0010876;phospholipid transport#GO:0015914;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;lipid transport#GO:0006869;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000007534.4|UniProtKB=F6PFS6 F6PFS6 PTHR14343:SF3 VWFA DOMAIN-CONTAINING PROTEIN SIMILAR TO HUMAN CHROMOSOME 11 OPEN READING FRAME 16 MONDO|Ensembl=ENSMODG00000001718.2|UniProtKB=F6XGD0 F6XGD0 PTHR45842:SF14 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEAT, IMMUNOGLOBULIN-LIKE DOMAIN AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000018658.4|UniProtKB=H9H767 H9H767 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of immune response#GO:0050776;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000043462.1|UniProtKB=A0A5F8H2W7 A0A5F8H2W7 CENPK PTHR14401:SF6 CENTROMERE PROTEIN K CENTROMERE PROTEIN K MONDO|Ensembl=ENSMODG00000050501.1|UniProtKB=K7E0C9 K7E0C9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000015872.4|UniProtKB=F7BR47 F7BR47 PTH2R PTHR45620:SF7 PDF RECEPTOR-LIKE PROTEIN-RELATED PARATHYROID HORMONE 2 RECEPTOR peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014636.4|UniProtKB=F6YPC1 F6YPC1 UBE2H PTHR24068:SF128 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 H acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000025573.3|UniProtKB=F6U2Z7 F6U2Z7 PTHR23084:SF263 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED MORN REPEAT-CONTAINING PROTEIN 1 transferase#PC00220;kinase#PC00137 MONDO|Ensembl=ENSMODG00000005702.3|UniProtKB=F6U4F9 F6U4F9 USP7 PTHR24006:SF644 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000017883.4|UniProtKB=F7GFM8 F7GFM8 TEKT2 PTHR19960:SF29 TEKTIN TEKTIN-2 cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cilium assembly#GO:0060271;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cell projection organization#GO:0030030;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;organelle assembly#GO:0070925;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000051446.1|UniProtKB=K7E6A3 K7E6A3 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000011588.4|UniProtKB=F7FZ12 F7FZ12 RASSF2 PTHR22738:SF14 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 2 regulation of signaling#GO:0023051;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;regulation of JNK cascade#GO:0046328;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007181.4|UniProtKB=F6XAN7 F6XAN7 CCDC174 PTHR15885:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 174 COILED-COIL DOMAIN-CONTAINING PROTEIN 174 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000016926.4|UniProtKB=F6VN33 F6VN33 HSPA14 PTHR19375:SF438 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN 14 binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111 protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072;Hsp70 family chaperone#PC00027 MONDO|Ensembl=ENSMODG00000004806.3|UniProtKB=F6V646 F6V646 TSHB PTHR11515:SF5 GLYCOPROTEIN HORMONE BETA CHAIN THYROTROPIN SUBUNIT BETA receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 Thyrotropin-releasing hormone receptor signaling pathway#P04394>Thyrotropin#P04588;Thyrotropin-releasing hormone receptor signaling pathway#P04394>ProTRH (Pro Thyrotropin-releasing Hormone)#P04586;Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH#P04585 MONDO|Ensembl=ENSMODG00000036949.1|UniProtKB=A0A5F8HFK2 A0A5F8HFK2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000010474.3|UniProtKB=F7ET14 F7ET14 GOLGA7 PTHR13254:SF1 GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A, 7 GOLGIN SUBFAMILY A MEMBER 7 protein targeting to membrane#GO:0006612;protein localization to cell periphery#GO:1990778;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;localization#GO:0051179;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;Golgi to plasma membrane transport#GO:0006893;protein targeting#GO:0006605;Golgi to plasma membrane protein transport#GO:0043001 Golgi apparatus subcompartment#GO:0098791;Golgi stack#GO:0005795;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000017193.3|UniProtKB=F6XXM9 F6XXM9 AQP10 PTHR43829:SF13 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-10 passive transmembrane transporter activity#GO:0022803;water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;carbohydrate transmembrane transporter activity#GO:0015144 cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643;transport#GO:0006810;localization#GO:0051179;water transport#GO:0006833;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;fluid transport#GO:0042044;organic hydroxy compound transport#GO:0015850 membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000020963.4|UniProtKB=F6SNE9 F6SNE9 BACE2 PTHR47965:SF40 ASPARTYL PROTEASE-RELATED BETA-SECRETASE 2 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;membrane protein ectodomain proteolysis#GO:0006509;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;membrane protein proteolysis#GO:0033619;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 Golgi apparatus#GO:0005794;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;plasma membrane#GO:0005886;endomembrane system#GO:0012505;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190 Alzheimer disease-presenilin pathway#P00004>Pro-BACE-1#P00162;Alzheimer disease-amyloid secretase pathway#P00003>Pro-BACE-1#P00081;Alzheimer disease-presenilin pathway#P00004>BACE-1 pro-domain#P00178;Alzheimer disease-amyloid secretase pathway#P00003>BACE-1 pro-domain#P00094;Alzheimer disease-presenilin pathway#P00004>BACE-1#P00172;Alzheimer disease-amyloid secretase pathway#P00003>BACE-1#P00101 MONDO|Ensembl=ENSMODG00000051165.1|UniProtKB=A0A5F8HDX0 A0A5F8HDX0 MTRFR PTHR46203:SF1 PROBABLE PEPTIDE CHAIN RELEASE FACTOR C12ORF65 MITOCHONDRIAL TRANSLATION RELEASE FACTOR IN RESCUE cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 translation release factor#PC00225 MONDO|Ensembl=ENSMODG00000036817.1|UniProtKB=A0A5F8HDX3 A0A5F8HDX3 OVOL1 PTHR10032:SF217 ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS TRANSCRIPTION FACTOR OVO-LIKE 1-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;epidermis development#GO:0008544;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000025429.3|UniProtKB=F6W268 F6W268 LOC100616681 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008239.3|UniProtKB=A0A5F8H8W5 A0A5F8H8W5 OCM PTHR11653:SF4 PARVALBUMIN ALPHA ONCOMODULIN-2 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000017652.3|UniProtKB=F6YKE5 F6YKE5 LOC100025096 PTHR12422:SF2 GH09096P CYRIA_CYRIB RAC1 BINDING DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000020286.4|UniProtKB=F7C0E8 F7C0E8 FBXO4 PTHR16008:SF4 F-BOX ONLY PROTEIN 4 F-BOX ONLY PROTEIN 4 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 MONDO|Ensembl=ENSMODG00000036606.1|UniProtKB=F7A7F1 F7A7F1 LOC100022796 PTHR26452:SF695 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000014526.4|UniProtKB=A0A5F8H0L6 A0A5F8H0L6 CEP41 PTHR44390:SF1 CENTROSOMAL PROTEIN OF 41 KDA CENTROSOMAL PROTEIN OF 41 KDA organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000023277.3|UniProtKB=F6SWN5 F6SWN5 TMEM242 PTHR13141:SF4 TRANSMEMBRANE PROTEIN 242 TRANSMEMBRANE PROTEIN 242 MONDO|Ensembl=ENSMODG00000050135.1|UniProtKB=A0A5F8HKQ1 A0A5F8HKQ1 PTHR14003:SF32 TRANSCRIPTIONAL REPRESSOR PROTEIN YY ZKSCAN8 PSEUDOGENE 1 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000001914.4|UniProtKB=F6W1C4 F6W1C4 FAM169A PTHR22442:SF3 FAMILY NOT NAMED SOLUBLE LAMIN-ASSOCIATED PROTEIN OF 75 KDA MONDO|Ensembl=ENSMODG00000042603.1|UniProtKB=A0A5F8GXX2 A0A5F8GXX2 TMEM104 PTHR16189:SF0 TRANSMEMBRANE PROTEIN 104-RELATED SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 12-RELATED MONDO|Ensembl=ENSMODG00000012658.3|UniProtKB=A0A5F8HI60 A0A5F8HI60 GLRX5 PTHR10293:SF16 GLUTAREDOXIN FAMILY MEMBER GLUTAREDOXIN-RELATED PROTEIN 5, MITOCHONDRIAL oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000029462.2|UniProtKB=K7E128 K7E128 PTHR35978:SF1 IQ DOMAIN-CONTAINING PROTEIN M IQ DOMAIN-CONTAINING PROTEIN M MONDO|Ensembl=ENSMODG00000017029.4|UniProtKB=F6Y0F0 F6Y0F0 HGF PTHR24261:SF8 PLASMINOGEN-RELATED HEPATOCYTE GROWTH FACTOR catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;signaling receptor binding#GO:0005102;binding#GO:0005488;hydrolase activity#GO:0016787;protein binding#GO:0005515 negative regulation of cellular process#GO:0048523;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000044477.1|UniProtKB=A0A5F8GMK3 A0A5F8GMK3 CHRAC1 PTHR10252:SF153 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED CHROMATIN ACCESSIBILITY COMPLEX PROTEIN 1 primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular process#GO:0009987;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ISWI-type complex#GO:0031010;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000025371.2|UniProtKB=F6ZZJ9 F6ZZJ9 PTHR15431:SF9 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN CENTROSOMAL PROTEIN 43 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000006618.3|UniProtKB=F7GEU1 F7GEU1 CDIP1 PTHR23292:SF7 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR CELL DEATH-INDUCING P53-TARGET PROTEIN 1 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;zinc ion binding#GO:0008270;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914 response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;regulation of cellular process#GO:0050794;signaling#GO:0023052;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell death#GO:0008219;apoptotic process#GO:0006915;cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;intracellular signal transduction#GO:0035556;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;biological regulation#GO:0065007;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974 lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;side of membrane#GO:0098552;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765;nucleus#GO:0005634;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;vacuole#GO:0005773;cytoplasm#GO:0005737;late endosome membrane#GO:0031902;cytoplasmic side of membrane#GO:0098562;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013069.4|UniProtKB=F7FPZ6 F7FPZ6 HHIPL1 PTHR19328:SF32 HEDGEHOG-INTERACTING PROTEIN HHIP-LIKE PROTEIN 1 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000014817.3|UniProtKB=F7D2C1 F7D2C1 KCNF1 PTHR11537:SF171 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL REGULATORY SUBUNIT KCNF1 ion channel regulator activity#GO:0099106;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;action potential#GO:0001508;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000020086.4|UniProtKB=F7EST3 F7EST3 ELL2 PTHR23288:SF8 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;nucleic acid biosynthetic process#GO:0141187;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;snRNA transcription#GO:0009301;regulation of biological process#GO:0050789;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;snRNA metabolic process#GO:0016073;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA transcription by RNA polymerase II#GO:0042795;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;transcription by RNA polymerase II#GO:0006366;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000014872.3|UniProtKB=F6YKW0 F6YKW0 PTHR24068:SF429 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 E2 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein K63-linked ubiquitination#GO:0070534;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein K11-linked ubiquitination#GO:0070979;post-translational protein modification#GO:0043687;ISG15-protein conjugation#GO:0032020;protein ubiquitination#GO:0016567 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000000311.4|UniProtKB=F6VV52 F6VV52 SYDE2 PTHR46150:SF1 RHO GTPASE-ACTIVATING PROTEIN 100F RHO GTPASE-ACTIVATING PROTEIN SYDE2 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell migration#GO:0016477;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of Ras protein signal transduction#GO:0046578;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 membrane#GO:0016020;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000010730.3|UniProtKB=F7G7G9 F7G7G9 RBM48 PTHR20957:SF0 RNA-BINDING PROTEIN 48 RNA-BINDING PROTEIN 48 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000003866.4|UniProtKB=A0A5F8HC31 A0A5F8HC31 BPTF PTHR45975:SF2 NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF MONDO|Ensembl=ENSMODG00000004913.4|UniProtKB=F7C1N5 F7C1N5 SERPINE1 PTHR11461:SF49 SERINE PROTEASE INHIBITOR, SERPIN PLASMINOGEN ACTIVATOR INHIBITOR 1 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135 positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of response to wounding#GO:1903034;regulation of multicellular organismal process#GO:0051239;negative regulation of response to external stimulus#GO:0032102;regulation of response to external stimulus#GO:0032101;regulation of proteolysis#GO:0030162;regulation of anatomical structure morphogenesis#GO:0022603;negative regulation of response to wounding#GO:1903035;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of wound healing#GO:0061041;negative regulation of metabolic process#GO:0009892;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;negative regulation of hemostasis#GO:1900047;positive regulation of coagulation#GO:0050820;regulation of biological quality#GO:0065008;negative regulation of coagulation#GO:0050819;regulation of hemostasis#GO:1900046;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of wound healing#GO:0061045;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;regulation of coagulation#GO:0050818;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of vasculature development#GO:1901342;negative regulation of cellular process#GO:0048523;negative regulation of blood coagulation#GO:0030195;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of angiogenesis#GO:0016525;negative regulation of multicellular organismal process#GO:0051241;negative regulation of protein metabolic process#GO:0051248;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of angiogenesis#GO:0045765 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 Blood coagulation#P00011>PAI-1#P00411;p53 pathway#P00059>PAI#G04700;Plasminogen activating cascade#P00050>PAI-1#P01245;CCKR signaling map#P06959>PAI1#G07281;CCKR signaling map#P06959>PAI1#G06987 MONDO|Ensembl=ENSMODG00000017101.4|UniProtKB=F7G4I5 F7G4I5 CACNA1B PTHR45628:SF6 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT N-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1B transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832 monoatomic cation transmembrane transport#GO:0098655;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;import across plasma membrane#GO:0098739;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;calcium ion transmembrane transport#GO:0070588;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;calcium ion import#GO:0070509;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;trans-synaptic signaling#GO:0099537 transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;cell body#GO:0044297;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;transporter complex#GO:1990351;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991 voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>Ca2+ channel#P01022;GABA-B receptor II signaling#P05731>Ca channel#P05753;Endogenous cannabinoid signaling#P05730>Ca2+ channel#P05750;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ca2+channel#P00742;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041 MONDO|Ensembl=ENSMODG00000018335.4|UniProtKB=F6PRY6 F6PRY6 TSPAN9 PTHR19282:SF41 TETRASPANIN TETRASPANIN-9 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000021223.4|UniProtKB=F6U1A2 F6U1A2 DNER PTHR24044:SF467 NOTCH LIGAND FAMILY MEMBER DELTA AND NOTCH-LIKE EPIDERMAL GROWTH FACTOR-RELATED RECEPTOR protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000007778.4|UniProtKB=F7A998 F7A998 ACADSB PTHR43884:SF1 ACYL-COA DEHYDROGENASE SHORT_BRANCHED CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000041399.1|UniProtKB=A0A5F8GMS6 A0A5F8GMS6 IL15 PTHR14356:SF3 INTERLEUKIN-15-RELATED INTERLEUKIN-15 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125 regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of leukocyte proliferation#GO:0070665;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of lymphocyte proliferation#GO:0050670;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;positive regulation of lymphocyte proliferation#GO:0050671;regulation of immune response#GO:0050776;cell activation#GO:0001775;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127;positive regulation of lymphocyte activation#GO:0051251;leukocyte activation#GO:0045321;positive regulation of cell adhesion#GO:0045785;regulation of T cell proliferation#GO:0042129;regulation of macromolecule metabolic process#GO:0060255;regulation of cell-cell adhesion#GO:0022407;positive regulation of cytokine production#GO:0001819;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of leukocyte activation#GO:0002696;regulation of leukocyte proliferation#GO:0070663;positive regulation of mononuclear cell proliferation#GO:0032946;positive regulation of cell-cell adhesion#GO:0022409;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of T cell activation#GO:0050870;myeloid leukocyte activation#GO:0002274;regulation of T cell activation#GO:0050863;regulation of multicellular organismal process#GO:0051239;immune system process#GO:0002376;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of leukocyte activation#GO:0002694;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;positive regulation of T cell proliferation#GO:0042102;regulation of lymphocyte activation#GO:0051249 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;cytokine#PC00083;interleukin superfamily#PC00128 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870;Interleukin signaling pathway#P00036>Interleukin#P00970 MONDO|Ensembl=ENSMODG00000002640.4|UniProtKB=F7DIG7 F7DIG7 PARG PTHR12837:SF15 POLY ADP-RIBOSE GLYCOHYDROLASE POLY(ADP-RIBOSE) GLYCOHYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;macromolecule metabolic process#GO:0043170;regulation of primary metabolic process#GO:0080090;organophosphate metabolic process#GO:0019637;regulation of metabolic process#GO:0019222;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-sugar metabolic process#GO:0009225;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;regulation of cellular response to stress#GO:0080135;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;regulation of DNA metabolic process#GO:0051052;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000028240.2|UniProtKB=K7E0R1 K7E0R1 ARMT1 PTHR12260:SF6 DAMAGE-CONTROL PHOSPHATASE ARMT1 DAMAGE-CONTROL PHOSPHATASE 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 response to stimulus#GO:0050896;response to stress#GO:0006950;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000007998.4|UniProtKB=F7D588 F7D588 TAF6L PTHR10221:SF22 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 TAF6-LIKE RNA POLYMERASE II P300_CBP-ASSOCIATED FACTOR-ASSOCIATED FACTOR 65 KDA SUBUNIT 6L structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription initiation#GO:0006352;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 catalytic complex#GO:1902494;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;peptidase complex#GO:1905368;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123;SAGA complex#GO:0000124;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transcription factor TFIID complex#GO:0005669 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000015791.3|UniProtKB=F7FS41 F7FS41 DDX39B PTHR47958:SF124 ATP-DEPENDENT RNA HELICASE DBP3 SPLICEOSOME RNA HELICASE DDX39B macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;mRNA processing#GO:0006397;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA splicing, via transesterification reactions#GO:0000375;nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA biosynthetic process#GO:0032774 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000019254.4|UniProtKB=A0A5F8G5J6 A0A5F8G5J6 LOC100619142 PTHR11909:SF20 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242;Hedgehog signaling pathway#P00025>Casein kinase I#P00681 MONDO|Ensembl=ENSMODG00000018767.4|UniProtKB=F7DXP0 F7DXP0 SF3B4 PTHR48030:SF7 SPLICING FACTOR 3B SUBUNIT 4 SPLICING FACTOR 3B SUBUNIT 4 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U2 snRNP#GO:0005686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000011545.2|UniProtKB=F6QWU5 F6QWU5 GADD45GIP1 PTHR31761:SF1 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEINS-INTERACTING PROTEIN 1 GADD45GIP1 LARGE RIBOSOMAL SUBUNIT PROTEIN ML64 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000019654.4|UniProtKB=F6UAH2 F6UAH2 STOM PTHR10264:SF115 BAND 7 PROTEIN-RELATED STOMATIN ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000007731.4|UniProtKB=F7C479 F7C479 PTHR43294:SF1 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 2 potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;export from cell#GO:0140352;homeostatic process#GO:0042592;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000004762.4|UniProtKB=F6X133 F6X133 PTHR32083:SF32 CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 110 membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000039625.1|UniProtKB=F7AW83 F7AW83 OR4K2 PTHR48002:SF104 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019506.3|UniProtKB=A0A5F8GEL5 A0A5F8GEL5 GDPGP1 PTHR20884:SF8 GDP-D-GLUCOSE PHOSPHORYLASE 1 GDP-D-GLUCOSE PHOSPHORYLASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;carbohydrate metabolic process#GO:0005975;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular process#GO:0009987;glucose metabolic process#GO:0006006;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000018223.4|UniProtKB=A0A5F8G9W9 A0A5F8G9W9 DDX47 PTHR24031:SF790 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX47-RELATED RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000013073.4|UniProtKB=F7GG23 F7GG23 EP300 PTHR13808:SF29 CBP/P300-RELATED HISTONE ACETYLTRANSFERASE P300 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;chromatin DNA binding#GO:0031490;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;histone acetyltransferase activity#GO:0004402;DNA binding#GO:0003677;N-acetyltransferase activity#GO:0008080;chromatin binding#GO:0003682;acyltransferase activity#GO:0016746;nucleic acid binding#GO:0003676;protein-lysine-acetyltransferase activity#GO:0061733;transcription coactivator activity#GO:0003713;protein N-acetyltransferase activity#GO:0034212;transferase activity#GO:0016740;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;transcription regulator activity#GO:0140110;acetyltransferase activity#GO:0016407;binding#GO:0005488 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;histone acetyltransferase complex#GO:0000123;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493 histone modifying enzyme#PC00261 Wnt signaling pathway#P00057>CBP#P01448;Huntington disease#P00029>CBP#P00777;p53 pathway#P00059>P300#P04611;Gonadotropin-releasing hormone receptor pathway#P06664>p300#P06737;p53 pathway#P00059>CBP#P04623;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Transcription regulation by bZIP transcription factor#P00055>CBP/P300#P01387 MONDO|Ensembl=ENSMODG00000003842.5|UniProtKB=F7EBN5 F7EBN5 CDH15 PTHR24027:SF300 CADHERIN-23 CADHERIN-15 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell migration#GO:0016477;cell motility#GO:0048870;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000004966.4|UniProtKB=F7FL71 F7FL71 ANO4 PTHR12308:SF28 ANOCTAMIN ANOCTAMIN-4 intramembrane lipid carrier activity#GO:0140303;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;lipid transport#GO:0006869;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;macromolecule localization#GO:0033036;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000001800.4|UniProtKB=F6WI36 F6WI36 WASHC5 PTHR15691:SF6 WASH COMPLEX SUBUNIT 5 WASH COMPLEX SUBUNIT 5 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;organelle fission#GO:0048285;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;actin filament polymerization#GO:0030041;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125;endosome organization#GO:0007032;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000013947.4|UniProtKB=F6RT86 F6RT86 RAD50 PTHR18867:SF12 RAD50 DNA REPAIR PROTEIN RAD50 telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA repair#GO:0006281;RNA-templated DNA biosynthetic process#GO:0006278;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;reproductive process#GO:0022414;mitotic recombination#GO:0006312;sexual reproduction#GO:0019953;telomere organization#GO:0032200;organelle organization#GO:0006996;response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;telomere maintenance via telomere lengthening#GO:0010833;telomere maintenance via telomerase#GO:0007004;chromosome organization involved in meiotic cell cycle#GO:0070192;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;response to stimulus#GO:0050896;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793 MONDO|Ensembl=ENSMODG00000009386.4|UniProtKB=F6RDZ5 F6RDZ5 IMMT PTHR15415:SF7 MITOFILIN MICOS COMPLEX SUBUNIT MIC60 MONDO|Ensembl=ENSMODG00000024589.2|UniProtKB=F6PFW1 F6PFW1 ASCL3 PTHR13935:SF68 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE HOMOLOG 3 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000004667.4|UniProtKB=F6U762 F6U762 TENM4 PTHR11219:SF9 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-4 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 axon development#GO:0061564;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;cell junction organization#GO:0034330;synapse organization#GO:0050808;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell adhesion#GO:0007155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;synaptic membrane adhesion#GO:0099560 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000013779.4|UniProtKB=F6VXA2 F6VXA2 GJC2 PTHR11984:SF52 CONNEXIN GAP JUNCTION GAMMA-2 PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;regulation of biological process#GO:0050789;cellular process#GO:0009987 cell junction#GO:0030054;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 gap junction#PC00105;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000012114.3|UniProtKB=F7FU90 F7FU90 EXOSC2 PTHR21321:SF4 PNAS-3 RELATED EXOSOME COMPLEX COMPONENT RRP4 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 snRNA processing#GO:0016180;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule catabolic process#GO:0009057;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;snRNA 3'-end processing#GO:0034472;catabolic process#GO:0009056;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000004029.4|UniProtKB=K7E2L5 K7E2L5 TMC4 PTHR23302:SF45 TRANSMEMBRANE CHANNEL-RELATED VOLTAGE-GATED CHLORIDE CHANNEL TMC4 monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000015581.6|UniProtKB=A0A5F8GS09 A0A5F8GS09 SFSWAP PTHR13161:SF15 SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT SPLICING FACTOR, SUPPRESSOR OF WHITE-APRICOT HOMOLOG cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;alternative mRNA splicing, via spliceosome#GO:0000380;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000006398.3|UniProtKB=F7FRP8 F7FRP8 LOC130456393 PTHR14089:SF6 PRE-MRNA-SPLICING FACTOR RBM22 PRE-MRNA-SPLICING FACTOR RBM22 nucleic acid binding#GO:0003676;pre-mRNA binding#GO:0036002;binding#GO:0005488;snRNA binding#GO:0017069;RNA binding#GO:0003723 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000025261.3|UniProtKB=F7AMG1 F7AMG1 ITGAM PTHR23220:SF130 INTEGRIN ALPHA INTEGRIN ALPHA-M molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell surface receptor signaling pathway#GO:0007166;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609 protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;integrin complex#GO:0008305 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853 MONDO|Ensembl=ENSMODG00000011657.4|UniProtKB=F6YEN3 F6YEN3 UBA5 PTHR10953:SF9 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 5 catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782 post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000005712.2|UniProtKB=F6U4A8 F6U4A8 NEUROG2 PTHR19290:SF171 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIN-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;forebrain development#GO:0030900;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;head development#GO:0060322;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;developmental process#GO:0032502;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;plasma membrane bounded cell projection organization#GO:0120036;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000019377.4|UniProtKB=F6WSJ2 F6WSJ2 TM6SF1 PTHR14568:SF10 TRANSMEMBRANE SUPERFAMILY 6 MEMBER 1/2 TRANSMEMBRANE 6 SUPERFAMILY MEMBER 1 cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000002941.4|UniProtKB=F6PM51 F6PM51 OTULIN PTHR33662:SF2 OTU DEUBIQUITINASE WITH LINEAR LINKAGE-SPECIFICITY A-RELATED UBIQUITIN THIOESTERASE OTULIN catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;protein modification process#GO:0036211;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;regulation of signaling#GO:0023051;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;regulation of signal transduction#GO:0009966;regulation of response to cytokine stimulus#GO:0060759;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;regulation of cytokine-mediated signaling pathway#GO:0001959;regulation of response to stress#GO:0080134;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000000349.4|UniProtKB=F6QQY1 F6QQY1 LOC100012004 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000036793.1|UniProtKB=A0A5F8GJN9 A0A5F8GJN9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000028091.2|UniProtKB=K7E1H7 K7E1H7 PTHR47765:SF2 3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN EXONUCLEASE MUT-7 HOMOLOG MONDO|Ensembl=ENSMODG00000003441.4|UniProtKB=F7DX04 F7DX04 SLC30A7 PTHR45755:SF6 FAMILY NOT NAMED ZINC TRANSPORTER 7 monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;Golgi stack#GO:0005795;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi cis cisterna#GO:0000137;cytoplasm#GO:0005737;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791 MONDO|Ensembl=ENSMODG00000036581.1|UniProtKB=A0A5F8G2G2 A0A5F8G2G2 PTHR45617:SF101 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH ALPHA-2-GLYCOPROTEIN signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;protein binding#GO:0005515 regulation of anatomical structure morphogenesis#GO:0022603;morphogenesis of an epithelium#GO:0002009;regulation of multicellular organismal process#GO:0051239;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of signaling#GO:0023056;wound healing#GO:0042060;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;positive regulation of angiogenesis#GO:0045766;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of vasculature development#GO:1901342;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;epithelium development#GO:0060429;cell migration#GO:0016477;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to wounding#GO:0009611;positive regulation of cellular process#GO:0048522;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;regulation of angiogenesis#GO:0045765;positive regulation of cell communication#GO:0010647;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000036572.1|UniProtKB=A0A5F8GUB0 A0A5F8GUB0 CHTF8 PTHR28605:SF1 CTF8, CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 HOMOLOG (S. CEREVISIAE) CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;positive regulation of DNA metabolic process#GO:0051054 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000004444.3|UniProtKB=F6RSY7 F6RSY7 PRPF4 PTHR19846:SF0 WD40 REPEAT PROTEIN U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP4 RNA processing factor#PC00147;RNA splicing factor#PC00148 mRNA splicing#P00058>U6#P01473;mRNA splicing#P00058>U4#P01476 MONDO|Ensembl=ENSMODG00000042932.1|UniProtKB=A0A5F8GF70 A0A5F8GF70 LOC103105183 PTHR19303:SF26 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003591.4|UniProtKB=F7FPU2 F7FPU2 PRKAA2 PTHR24343:SF303 SERINE/THREONINE KINASE 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;response to stimulus#GO:0050896;negative regulation of TORC1 signaling#GO:1904262;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;negative regulation of signal transduction#GO:0009968;localization#GO:0051179;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;negative regulation of TOR signaling#GO:0032007;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;intracellular protein localization#GO:0008104;positive regulation of catabolic process#GO:0009896;cellular response to glucose starvation#GO:0042149;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;macromolecule localization#GO:0033036;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway by glucose deprivation#P04397>AMPK#P04639 MONDO|Ensembl=ENSMODG00000005072.4|UniProtKB=F7AS58 F7AS58 PTHR47134:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11A TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11A death receptor activity#GO:0005035;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955 regulation of bone resorption#GO:0045124;response to peptide#GO:1901652;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of multicellular organismal process#GO:0051240;leukocyte differentiation#GO:0002521;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239;response to cytokine#GO:0034097;response to chemical#GO:0042221;cytokine-mediated signaling pathway#GO:0019221;osteoclast differentiation#GO:0030316;regulation of tissue remodeling#GO:0034103;cell communication#GO:0007154;tumor necrosis factor-mediated signaling pathway#GO:0033209;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;ossification#GO:0001503;developmental process#GO:0032502;cellular developmental process#GO:0048869;response to tumor necrosis factor#GO:0034612;regulation of bone remodeling#GO:0046850;biological regulation#GO:0065007;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040188.1|UniProtKB=A0A5F8GHF8 A0A5F8GHF8 PTHR11258:SF7 2-5 OLIGOADENYLATE SYNTHETASE 2'-5'-OLIGOADENYLATE SYNTHASE-LIKE PROTEIN 2 binding#GO:0005488;nucleic acid binding#GO:0003676;adenylyltransferase activity#GO:0070566;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 response to cytokine#GO:0034097;response to chemical#GO:0042221;defense response to other organism#GO:0098542;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to peptide#GO:1901652;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;biological regulation#GO:0065007;response to other organism#GO:0051707;immune response#GO:0006955;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;antiviral innate immune response#GO:0140374;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to virus#GO:0009615;cytokine-mediated signaling pathway#GO:0019221 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;cytosol#GO:0005829;organelle lumen#GO:0043233;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974 nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000019125.4|UniProtKB=F7EV42 F7EV42 GAS2L2 PTHR46756:SF14 TRANSGELIN GAS2-LIKE PROTEIN 2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 microtubule bundle formation#GO:0001578;actin filament-based process#GO:0030029;regulation of microtubule-based process#GO:0032886;supramolecular fiber organization#GO:0097435;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;protein localization to organelle#GO:0033365;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;actin filament organization#GO:0007015;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;protein localization to microtubule cytoskeleton#GO:0072698 intracellular organelle#GO:0043229;microtubule#GO:0005874;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;microtubule end#GO:1990752;organelle#GO:0043226;cellular anatomical structure#GO:0110165;stress fiber#GO:0001725;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;actomyosin#GO:0042641;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000005117.3|UniProtKB=F6YQ55 F6YQ55 SLC7A6OS PTHR31196:SF2 RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED MONDO|Ensembl=ENSMODG00000016783.3|UniProtKB=F7G693 F7G693 SLCO4A1 PTHR11388:SF164 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 4A1 secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000048703.1|UniProtKB=A0A5F8GLG2 A0A5F8GLG2 PTHR33166:SF1 GAG_P30 DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000017826.4|UniProtKB=F6ZXA8 F6ZXA8 KPNA5 PTHR23316:SF10 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-6 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein localization to organelle#GO:0033365;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 MONDO|Ensembl=ENSMODG00000014748.4|UniProtKB=F6YN37 F6YN37 SUGT1 PTHR45862:SF1 PROTEIN SGT1 HOMOLOG PROTEIN SGT1 HOMOLOG MONDO|Ensembl=ENSMODG00000011272.3|UniProtKB=F6X027 F6X027 LOC100021807 PTHR26450:SF63 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52Z1P olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000615.4|UniProtKB=A0A5F8GCM1 A0A5F8GCM1 SLC35F5 PTHR23051:SF0 SOLUTE CARRIER FAMILY 35, MEMBER F5 SOLUTE CARRIER FAMILY 35 MEMBER F5 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000017466.4|UniProtKB=A0A5F8H560 A0A5F8H560 DNAI7 PTHR20929:SF11 LUNG ADENOMA SUSCEPTIBILITY 1-RELATED DYNEIN AXONEMAL INTERMEDIATE CHAIN 7 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;membraneless organelle#GO:0043228;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000014885.4|UniProtKB=F7GGI2 F7GGI2 ENOX1 PTHR16001:SF6 ANGEL WING family ECTO-NOX DISULFIDE-THIOL EXCHANGER 1 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000051006.1|UniProtKB=K7E6A7 K7E6A7 LLPH PTHR34253:SF1 PROTEIN LLP HOMOLOG PROTEIN LLP HOMOLOG cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;developmental cell growth#GO:0048588;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;developmental growth involved in morphogenesis#GO:0060560;neuron projection extension#GO:1990138;neuron development#GO:0048666;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental growth#GO:0048589;cell growth#GO:0016049;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000015642.5|UniProtKB=A0A5F8GEB2 A0A5F8GEB2 SGF29 PTHR21539:SF0 SAGA-ASSOCIATED FACTOR 29 SAGA-ASSOCIATED FACTOR 29 cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;SAGA-type complex#GO:0070461;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000040307.1|UniProtKB=F6X1R6 F6X1R6 PTHR23411:SF39 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 1-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;antigen binding#GO:0003823;protein binding#GO:0005515 complement activation#GO:0006956;immune response#GO:0006955;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;response to other organism#GO:0051707;adaptive immune response#GO:0002250;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;response to bacterium#GO:0009617;regulation of immune response#GO:0050776;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;immune effector process#GO:0002252;antibacterial humoral response#GO:0019731;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;defense response to bacterium#GO:0042742;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000019662.3|UniProtKB=F6U9Z3 F6U9Z3 PTHR10462:SF26 GLYCOSYLTRANSFERASE-RELATED N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000025726.3|UniProtKB=F6T2B6 F6T2B6 OPALIN PTHR21102:SF0 OPALIN OPALIN cell-cell contact zone#GO:0044291;anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000005315.3|UniProtKB=F7DLK8 F7DLK8 THAP12 PTHR46289:SF16 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE MONDO|Ensembl=ENSMODG00000017085.4|UniProtKB=F6VKK2 F6VKK2 GBA1 PTHR11069:SF23 GLUCOSYLCERAMIDASE LYSOSOMAL ACID GLUCOSYLCERAMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;ceramide metabolic process#GO:0006672 MONDO|Ensembl=ENSMODG00000038026.1|UniProtKB=A0A5F8H7T0 A0A5F8H7T0 OSTC PTHR13160:SF4 OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487 membrane protein complex#GO:0098796;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000047569.1|UniProtKB=A0A5F8H739 A0A5F8H739 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009130.4|UniProtKB=A0A5F8HJ67 A0A5F8HJ67 LOC100022725 PTHR11566:SF50 DYNAMIN DYNAMIN-1-LIKE PROTEIN ISOFORM X1 ribonucleoside triphosphate phosphatase activity#GO:0017111;tubulin binding#GO:0015631;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;GTPase activity#GO:0003924;microtubule binding#GO:0008017 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;mitochondrial fission#GO:0000266;peroxisome organization#GO:0007031;organelle localization#GO:0051640;mitochondrion localization#GO:0051646;organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179 supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000021084.4|UniProtKB=A0A5F8HBK3 A0A5F8HBK3 DNMT3L PTHR23068:SF13 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED DNA (CYTOSINE-5)-METHYLTRANSFERASE 3-LIKE enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA methyltransferase#PC00013 MONDO|Ensembl=ENSMODG00000045748.1|UniProtKB=A0A5F8GI33 A0A5F8GI33 LOC103098694 PTHR35825:SF2 CASEIN KINASE II SUBUNIT ALPHA PRIME-INTERACTING PROTEIN CASEIN KINASE II SUBUNIT ALPHA'-INTERACTING PROTEIN MONDO|Ensembl=ENSMODG00000002602.4|UniProtKB=F7G4S9 F7G4S9 SYT14 PTHR46129:SF3 SYNAPTOTAGMIN 14, ISOFORM D SYNAPTOTAGMIN-14 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000010088.6|UniProtKB=F7BYZ7 F7BYZ7 SYVN1 PTHR22763:SF196 RING ZINC FINGER PROTEIN E3 UBIQUITIN-PROTEIN LIGASE SYNOVIOLIN catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;response to endoplasmic reticulum stress#GO:0034976;response to stimulus#GO:0050896;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000010187.4|UniProtKB=F6SU50 F6SU50 CRK PTHR19969:SF8 SH2-SH3 ADAPTOR PROTEIN-RELATED ADAPTER MOLECULE CRK protein tyrosine kinase binding#GO:1990782;binding#GO:0005488;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell migration#GO:0016477;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 CCKR signaling map#P06959>CRK#P07125;Integrin signalling pathway#P00034>Crk#P00933;Angiogenesis#P00005>Crk#P00207 MONDO|Ensembl=ENSMODG00000008685.4|UniProtKB=F6PXS9 F6PXS9 SEC23IP PTHR23509:SF4 PA-PL1 PHOSPHOLIPASE FAMILY SEC23-INTERACTING PROTEIN lipase activity#GO:0016298;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell development#GO:0048468;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;spermatid differentiation#GO:0048515;sexual reproduction#GO:0019953;spermatid development#GO:0007286;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;cellular process#GO:0009987;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708 metabolite interconversion enzyme#PC00262;phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000014159.4|UniProtKB=F6UN46 F6UN46 TAPBP PTHR23411:SF22 TAPASIN TAPASIN binding#GO:0005488;protein-containing complex binding#GO:0044877 protein-containing complex organization#GO:0043933;antigen processing and presentation#GO:0019882;cellular component organization or biogenesis#GO:0071840;immune system process#GO:0002376;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000008674.4|UniProtKB=A0A5F8GX28 A0A5F8GX28 ATP8A2 PTHR24092:SF98 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IB intramembrane lipid carrier activity#GO:0140303;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 anatomical structure development#GO:0048856;localization#GO:0051179;regulation of biological quality#GO:0065008;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;lipid localization#GO:0010876;generation of neurons#GO:0048699;cell differentiation#GO:0030154;organophosphate ester transport#GO:0015748;cell development#GO:0048468;lipid translocation#GO:0034204;cellular component organization#GO:0016043;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of membrane lipid distribution#GO:0097035;neurogenesis#GO:0022008;transport#GO:0006810;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lipid transport#GO:0006869;nervous system development#GO:0007399;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000045092.1|UniProtKB=A0A5F8GI53 A0A5F8GI53 PTHR14759:SF34 STOP PROTEIN MUCIN-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;regulation of microtubule-based process#GO:0032886;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789 cytoskeleton#GO:0005856;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;cis-Golgi network#GO:0005801;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000043842.1|UniProtKB=A0A5F8GDK3 A0A5F8GDK3 PTHR11771:SF216 LIPOXYGENASE ARACHIDONATE 12-LIPOXYGENASE, 12S-TYPE-LIKE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;icosanoid metabolic process#GO:0006690;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;lipid oxidation#GO:0034440;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;arachidonate metabolic process#GO:0019369;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000010053.3|UniProtKB=F6TCW6 F6TCW6 DUSP23 PTHR23339:SF26 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 23 hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000008111.3|UniProtKB=F7G5J1 F7G5J1 PTHR31437:SF1 SREK1IP1 FAMILY MEMBER PROTEIN SREK1IP1 MONDO|Ensembl=ENSMODG00000013441.4|UniProtKB=F7G9V1 F7G9V1 KRT25 PTHR23239:SF160 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 25 structural molecule activity#GO:0005198 cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;intermediate filament organization#GO:0045109;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;cytoskeleton organization#GO:0007010;skin development#GO:0043588;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;cellular process#GO:0009987;organelle organization#GO:0006996;morphogenesis of an epithelium#GO:0002009;cellular developmental process#GO:0048869;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;epidermis development#GO:0008544 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000006297.4|UniProtKB=A0A5F8H393 A0A5F8H393 ABCA5 PTHR19229:SF100 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA CHOLESTEROL TRANSPORTER ABCA5 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 establishment of localization#GO:0051234;lipid transport#GO:0006869;localization#GO:0051179;transport#GO:0006810;lipid localization#GO:0010876;macromolecule localization#GO:0033036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000011802.5|UniProtKB=F7CBL2 F7CBL2 GFI1 PTHR24404:SF46 ZINC FINGER PROTEIN ZINC FINGER PROTEIN GFI-1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000044089.1|UniProtKB=K7E1Q5 K7E1Q5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000051203.1|UniProtKB=F7B6I8 F7B6I8 LOC100030038 PTHR48018:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 974 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009155.4|UniProtKB=F7B0K9 F7B0K9 GALNT2 PTHR11675:SF49 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 2 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096 biosynthetic process#GO:0009058;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000006683.3|UniProtKB=F7FFJ7 F7FFJ7 DOLPP1 PTHR11247:SF82 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 DOLICHYLDIPHOSPHATASE 1 hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000024777.1|UniProtKB=F7D3Y7 F7D3Y7 AK6 PTHR12595:SF0 POS9-ACTIVATING FACTOR FAP7-RELATED ADENYLATE KINASE ISOENZYME 6 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;kinase activity#GO:0016301;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside phosphate binding#GO:1901265;nucleobase-containing compound kinase activity#GO:0019205;ATP binding#GO:0005524;binding#GO:0005488;nucleotide binding#GO:0000166;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000013985.4|UniProtKB=F6QKZ9 F6QKZ9 MACO1 PTHR13289:SF6 PROTEIN PHOSPHATASE 1-BINDING PROTEIN BIFOCAL MACOILIN protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cell communication#GO:0007154;response to external stimulus#GO:0009605;chemotaxis#GO:0006935;regulation of cellular process#GO:0050794;taxis#GO:0042330;response to chemical#GO:0042221;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 nucleus#GO:0005634;membrane#GO:0016020;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;nuclear membrane#GO:0031965;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;rough endoplasmic reticulum#GO:0005791 transporter#PC00227 MONDO|Ensembl=ENSMODG00000049786.1|UniProtKB=A0A5F8GY58 A0A5F8GY58 PTHR26453:SF232 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2A5 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007012.4|UniProtKB=A0A5F8HAQ3 A0A5F8HAQ3 NAP1L4 PTHR11875:SF75 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1-LIKE 4 chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;chromatin remodeling#GO:0006338;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000009929.2|UniProtKB=F6R8M5 F6R8M5 SLITRK6 PTHR45773:SF1 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 6 regulation of biological quality#GO:0065008;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;regulation of synapse organization#GO:0050807;cell differentiation#GO:0030154;cell projection organization#GO:0030030;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of cellular component biogenesis#GO:0044089;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;system development#GO:0048731;regulation of cell junction assembly#GO:1901888;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;cellular developmental process#GO:0048869;positive regulation of synapse assembly#GO:0051965;neurogenesis#GO:0022008;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;neuron projection morphogenesis#GO:0048812;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;positive regulation of cellular process#GO:0048522 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000042561.1|UniProtKB=A0A5F8GMN3 A0A5F8GMN3 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000018645.4|UniProtKB=H9H8Q3 H9H8Q3 PLEKHN1 PTHR46882:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY N MEMBER 1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY N MEMBER 1 phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;response to hypoxia#GO:0001666;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;response to stress#GO:0006950;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;positive regulation of apoptotic process#GO:0043065;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of apoptotic process#GO:0042981;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;response to abiotic stimulus#GO:0009628;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000018557.4|UniProtKB=A0A5F8GQ63 A0A5F8GQ63 RIMS1 PTHR12157:SF18 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 1 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of neurotransmitter secretion#GO:0046928;regulation of synaptic vesicle exocytosis#GO:2000300;signaling#GO:0023052;export from cell#GO:0140352;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;cellular localization#GO:0051641;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;neurotransmitter transport#GO:0006836;regulated exocytosis#GO:0045055;exocytic process#GO:0140029;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;exocytosis#GO:0006887;regulation of localization#GO:0032879;regulation of transport#GO:0051049;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;regulation of secretion#GO:0051046;cell communication#GO:0007154;localization#GO:0051179;regulation of exocytosis#GO:0017157;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234 synaptic membrane#GO:0097060;cell junction#GO:0030054;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell cortex#GO:0005938;presynapse#GO:0098793;cell periphery#GO:0071944;plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737 membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>RIM1alpha/2alpha#P05776 MONDO|Ensembl=ENSMODG00000023292.1|UniProtKB=F6VTB2 F6VTB2 LOC100032735 PTHR26453:SF124 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1342 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020669.4|UniProtKB=A0A5F8G3D5 A0A5F8G3D5 MANBA PTHR43730:SF1 BETA-MANNOSIDASE BETA-MANNOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 glycoprotein metabolic process#GO:0009100;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000012056.4|UniProtKB=F7GF75 F7GF75 BARHL2 PTHR24333:SF12 HOMEO BOX HB9 LIKE A-RELATED BARX HOMEOBOX 1 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000004668.4|UniProtKB=A0A5F8H498 A0A5F8H498 EPO PTHR10370:SF0 ERYTHROPOIETIN ERYTHROPOIETIN molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;cytokine receptor binding#GO:0005126;binding#GO:0005488;cytokine activity#GO:0005125;protein kinase regulator activity#GO:0019887;signaling receptor activator activity#GO:0030546;kinase regulator activity#GO:0019207;enzyme activator activity#GO:0008047;hormone activity#GO:0005179;signaling receptor binding#GO:0005102;kinase activator activity#GO:0019209;molecular function regulator activity#GO:0098772;protein kinase activator activity#GO:0030295;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 multicellular organismal-level homeostasis#GO:0048871;cellular developmental process#GO:0048869;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cell surface receptor signaling pathway via STAT#GO:0097696;hemopoiesis#GO:0030097;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to peptide#GO:1901652;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;cell communication#GO:0007154;homeostasis of number of cells#GO:0048872;cytokine-mediated signaling pathway#GO:0019221;immune system process#GO:0002376;cell development#GO:0048468;signaling#GO:0023052;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000048078.1|UniProtKB=A0A5F8G1M4 A0A5F8G1M4 C1QTNF1 PTHR22923:SF125 CEREBELLIN-RELATED C1Q AND TNF RELATED 1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000012740.5|UniProtKB=H9H6L1 H9H6L1 PTHR15205:SF1 DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN DNA-BINDING DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN 2 programmed cell death#GO:0012501;cell death#GO:0008219;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;signaling#GO:0023052;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;apoptotic signaling pathway#GO:0097190;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000018017.4|UniProtKB=F7AKG3 F7AKG3 ANO2 PTHR12308:SF20 ANOCTAMIN ANOCTAMIN-2 gated channel activity#GO:0022836;molecular carrier activity#GO:0140104;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;chloride channel activity#GO:0005254;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;phospholipid scramblase activity#GO:0017128;ligand-gated monoatomic ion channel activity#GO:0015276;lipid carrier activity#GO:0005319;channel activity#GO:0015267;intramembrane lipid carrier activity#GO:0140303;monoatomic anion channel activity#GO:0005253;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803 monoatomic anion transport#GO:0006820;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;lipid localization#GO:0010876;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;monoatomic anion transmembrane transport#GO:0098656;phospholipid transport#GO:0015914;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000019045.3|UniProtKB=F7AYE1 F7AYE1 MRPS10 PTHR13334:SF4 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S10 SMALL RIBOSOMAL SUBUNIT PROTEIN US10M mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000001406.4|UniProtKB=A0A5F8G432 A0A5F8G432 ZYX PTHR24212:SF1 ZYXIN/TRIP6 ZYXIN cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to transforming growth factor beta#GO:0071559;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;integrin-mediated signaling pathway#GO:0007229 actin cytoskeleton#GO:0015629;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;actin filament bundle#GO:0032432;actomyosin#GO:0042641;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000006876.4|UniProtKB=A0A5F8HCG5 A0A5F8HCG5 PLSCR3 PTHR23248:SF37 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE 3 intramembrane lipid carrier activity#GO:0140303;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215 plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;programmed cell death#GO:0012501;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;localization#GO:0051179;lipid localization#GO:0010876;regulation of release of cytochrome c from mitochondria#GO:0090199;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000011106.4|UniProtKB=F6SR06 F6SR06 PTHR24377:SF980 IP01015P-RELATED ZINC FINGER PROTEIN 420 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000029536.2|UniProtKB=K7E287 K7E287 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000021551.5|UniProtKB=A0A5F8HJY6 A0A5F8HJY6 KBTBD2 PTHR24412:SF192 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000046062.1|UniProtKB=A0A5F8GK71 A0A5F8GK71 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000004437.2|UniProtKB=F6RTZ2 F6RTZ2 PTHR45660:SF13 HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR double-stranded DNA binding#GO:0003690;histone modifying activity#GO:0140993;DNA binding#GO:0003677;histone methyltransferase activity#GO:0042054;binding#GO:0005488;nucleic acid binding#GO:0003676;methyltransferase activity#GO:0008168;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000000513.3|UniProtKB=F6Y5N6 F6Y5N6 DNASE2B PTHR10858:SF2 DEOXYRIBONUCLEASE II DEOXYRIBONUCLEASE-2-BETA nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;catabolic process#GO:0009056;programmed cell death#GO:0012501;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cell death#GO:0008219 endodeoxyribonuclease#PC00093 MONDO|Ensembl=ENSMODG00000050795.1|UniProtKB=A0A5F8GS75 A0A5F8GS75 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000000910.4|UniProtKB=A0A5F8GIS6 A0A5F8GIS6 LDB2 PTHR10378:SF8 LIM DOMAIN-BINDING PROTEIN LIM DOMAIN-BINDING PROTEIN 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000047369.1|UniProtKB=A0A5F8HFS2 A0A5F8HFS2 LHFPL6 PTHR12489:SF12 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 6 PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019527.3|UniProtKB=F6VCF5 F6VCF5 SRXN1 PTHR21348:SF4 FAMILY NOT NAMED SULFIREDOXIN-1 oxidoreductase activity#GO:0016491;antioxidant activity#GO:0016209;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000017802.4|UniProtKB=F7CFG2 F7CFG2 GRIK3 PTHR18966:SF174 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 3 carboxylic acid transmembrane transporter activity#GO:0046943;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;sodium ion transmembrane transporter activity#GO:0015081;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic cation channel activity#GO:0005261;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;signaling receptor activity#GO:0038023;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216 regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051 transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;cation channel complex#GO:0034703;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;sodium channel complex#GO:0034706;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA3#P01002;Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>KA#P01026 MONDO|Ensembl=ENSMODG00000003600.3|UniProtKB=F7C6M6 F7C6M6 RARRES2 PTHR15106:SF2 RETINOIC ACID RECEPTOR RESPONDER PROTEIN 2 RETINOIC ACID RECEPTOR RESPONDER PROTEIN 2 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;defense response#GO:0006952;regulation of catabolic process#GO:0009894;positive regulation of response to external stimulus#GO:0032103;innate immune response#GO:0045087;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;immune response#GO:0006955;regulation of primary metabolic process#GO:0080090;response to biotic stimulus#GO:0009607;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;immune system process#GO:0002376;regulation of lipid metabolic process#GO:0019216;positive regulation of chemotaxis#GO:0050921;regulation of lipid catabolic process#GO:0050994;regulation of biological process#GO:0050789;regulation of chemotaxis#GO:0050920;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000006456.4|UniProtKB=F6SJQ4 F6SJQ4 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;aminoglycan biosynthetic process#GO:0006023;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;glycoprotein metabolic process#GO:0009100;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000001505.4|UniProtKB=F6VWN3 F6VWN3 ZNF771 PTHR19818:SF177 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN 71 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004384.4|UniProtKB=F6SVY9 F6SVY9 TMEM126A PTHR16296:SF4 UNCHARACTERIZED HYPOTHALAMUS PROTEIN HT007 TRANSMEMBRANE PROTEIN 126A cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000047173.1|UniProtKB=A0A5F8HJ66 A0A5F8HJ66 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000006790.4|UniProtKB=A0A5F8H8I2 A0A5F8H8I2 TTLL12 PTHR46088:SF1 TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12 TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000017113.4|UniProtKB=F6UJH7 F6UJH7 EHMT1 PTHR46307:SF2 G9A, ISOFORM B HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000013913.2|UniProtKB=A0A5F8GM71 A0A5F8GM71 REXO2 PTHR11046:SF0 OLIGORIBONUCLEASE, MITOCHONDRIAL OLIGORIBONUCLEASE, MITOCHONDRIAL hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000045248.1|UniProtKB=A0A5F8G2W5 A0A5F8G2W5 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000027696.2|UniProtKB=K7E228 K7E228 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024268.1|UniProtKB=F7GKW8 F7GKW8 LOC100016691 PTHR48018:SF157 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011936.4|UniProtKB=F7DEK0 F7DEK0 TMEM266 PTHR46842:SF1 TRANSMEMBRANE PROTEIN 266 TRANSMEMBRANE PROTEIN 266 MONDO|Ensembl=ENSMODG00000004358.3|UniProtKB=F6WPS6 F6WPS6 POLE3 PTHR46172:SF1 DNA POLYMERASE EPSILON SUBUNIT 3 DNA POLYMERASE EPSILON SUBUNIT 3 nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;chromatin DNA binding#GO:0031490;DNA binding#GO:0003677 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896 nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;epsilon DNA polymerase complex#GO:0008622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ISWI-type complex#GO:0031010 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000013463.4|UniProtKB=F7FYV1 F7FYV1 LRFN1 PTHR45842:SF7 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 1 synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000040058.1|UniProtKB=A0A5F8H5H1 A0A5F8H5H1 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000041818.1|UniProtKB=A0A5F8HED8 A0A5F8HED8 LOC100028235 PTHR48002:SF122 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4F6 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001372.3|UniProtKB=F7FJM0 F7FJM0 PTHR47966:SF70 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSIN B aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 protease#PC00190;aspartic protease#PC00053 MONDO|Ensembl=ENSMODG00000005486.3|UniProtKB=F7BXY9 F7BXY9 GPX4 PTHR11592:SF134 GLUTATHIONE PEROXIDASE PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE GPX4 catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular process#GO:0009987;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;icosanoid metabolic process#GO:0006690;cellular response to stress#GO:0033554;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281 peroxidase#PC00180;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000000691.4|UniProtKB=F6WM17 F6WM17 PRMT9 PTHR11006:SF60 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 9 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000050495.1|UniProtKB=A0A5F8G332 A0A5F8G332 CDKN2C PTHR24134:SF25 ANKYRIN REPEAT-CONTAINING PROTEIN DDB_G0279043 CYCLIN-DEPENDENT KINASE 4 INHIBITOR C-RELATED p53 pathway#P00059>ARF#P01482;p53 pathway#P00059>ARF#G01574 MONDO|Ensembl=ENSMODG00000019532.3|UniProtKB=A0A5F8G3U7 A0A5F8G3U7 FAM110A PTHR14758:SF4 AGAP005440-PA PROTEIN FAM110A MONDO|Ensembl=ENSMODG00000025178.3|UniProtKB=F7FXK7 F7FXK7 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000044814.1|UniProtKB=A0A5F8GXY4 A0A5F8GXY4 PTHR23411:SF39 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 1-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;antigen binding#GO:0003823;protein binding#GO:0005515 response to external biotic stimulus#GO:0043207;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;response to bacterium#GO:0009617;response to other organism#GO:0051707;adaptive immune response#GO:0002250;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;complement activation#GO:0006956;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;defense response to bacterium#GO:0042742;immune system process#GO:0002376;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;antibacterial humoral response#GO:0019731;immune effector process#GO:0002252;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000023954.1|UniProtKB=F7A538 F7A538 IER2 PTHR15895:SF4 IMMEDIATE EARLY RESPONSE GENE IMMEDIATE EARLY RESPONSE GENE 2 PROTEIN MONDO|Ensembl=ENSMODG00000006637.4|UniProtKB=F7G4C1 F7G4C1 GPR139 PTHR46272:SF3 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G PROTEIN-COUPLED RECEPTOR 139-RELATED signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154 MONDO|Ensembl=ENSMODG00000044461.1|UniProtKB=A0A5F8HCC9 A0A5F8HCC9 LOC100028476 PTHR24384:SF261 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 719 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000015500.4|UniProtKB=A0A5F8GMS9 A0A5F8GMS9 XDH PTHR11908:SF80 XANTHINE DEHYDROGENASE XANTHINE DEHYDROGENASE_OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;purine-containing compound catabolic process#GO:0072523;purine nucleobase catabolic process#GO:0006145;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Purine metabolism#P02769>Xanthine Oxidase#P03116;Adenine and hypoxanthine salvage pathway#P02723>Xanthine dehydrogenase#P02809 MONDO|Ensembl=ENSMODG00000003495.4|UniProtKB=F7CS22 F7CS22 GAS1 PTHR16840:SF3 GROWTH ARREST-SPECIFIC PROTEIN 1 GROWTH ARREST-SPECIFIC PROTEIN 1 regulation of transport#GO:0051049;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000043050.1|UniProtKB=A0A5F8GFR2 A0A5F8GFR2 PTHR35662:SF1 INTERACTOR OF HORMAD1 PROTEIN 1 INTERACTOR OF HORMAD1 PROTEIN 1 nucleobase-containing compound metabolic process#GO:0006139;homologous chromosome pairing at meiosis#GO:0007129;cellular process#GO:0009987;organelle organization#GO:0006996;meiotic DNA double-strand break formation#GO:0042138;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;reproductive process#GO:0022414;cell cycle process#GO:0022402;cell cycle#GO:0007049;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;condensed chromosome#GO:0000793;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000003557.3|UniProtKB=F7GBC6 F7GBC6 RTCA PTHR11096:SF0 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;cyclase activity#GO:0009975;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000049221.1|UniProtKB=A0A5F8GNA4 A0A5F8GNA4 PTHR45771:SF2 HOMEOTIC PROTEIN DEFORMED HOMEOBOX PROTEIN HOX-A4 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;anterior/posterior pattern specification#GO:0009952;embryo development#GO:0009790;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;skeletal system development#GO:0001501;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regionalization#GO:0003002;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;skeletal system morphogenesis#GO:0048705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000018742.4|UniProtKB=A0A5F8GF32 A0A5F8GF32 GPR89A PTHR15948:SF8 G-PROTEIN COUPLED RECEPTOR 89-RELATED GOLGI PH REGULATOR A-RELATED gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;channel activity#GO:0015267;voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 biological regulation#GO:0065007;homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;regulation of intracellular pH#GO:0051453 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000020337.4|UniProtKB=F6WXF3 F6WXF3 ZP1 PTHR23343:SF41 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 1 binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198 regulation of biological process#GO:0050789;cellular process#GO:0009987;negative regulation of biological process#GO:0048519;single fertilization#GO:0007338;biological regulation#GO:0065007;fertilization#GO:0009566;reproductive process#GO:0022414;regulation of reproductive process#GO:2000241;multicellular organismal process#GO:0032501;sexual reproduction#GO:0019953;cell activation#GO:0001775;cell recognition#GO:0008037;sperm-egg recognition#GO:0035036;cell-cell recognition#GO:0009988;binding of sperm to zona pellucida#GO:0007339 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000019543.3|UniProtKB=F6UUC2 F6UUC2 TMEM74B PTHR16125:SF4 TRANSMEMBRANE PROTEIN 74 TRANSMEMBRANE PROTEIN 74B MONDO|Ensembl=ENSMODG00000014488.4|UniProtKB=F7FKU0 F7FKU0 PTHR11337:SF11 MUCIN/PORIMIN CD164 SIALOMUCIN-LIKE 2 PROTEIN intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000006382.5|UniProtKB=F7G276 F7G276 DVL1 PTHR10878:SF5 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-1-RELATED protein binding#GO:0005515;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell surface receptor signaling pathway#GO:0007166 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Alzheimer disease-presenilin pathway#P00004>Dsh#P00132;Angiogenesis#P00005>Dsh#P00200;Wnt signaling pathway#P00057>Dishevelled#P01447 MONDO|Ensembl=ENSMODG00000050204.1|UniProtKB=A0A5F8H9X4 A0A5F8H9X4 DUSP1 PTHR10159:SF309 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 1 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 cell communication#GO:0007154;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signaling#GO:0023057;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;formation of primary germ layer#GO:0001704;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;gastrulation#GO:0007369;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;anatomical structure formation involved in morphogenesis#GO:0048646;endoderm development#GO:0007492;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;endoderm formation#GO:0001706;embryo development#GO:0009790 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131;Gonadotropin-releasing hormone receptor pathway#P06664>DUSP1#P06823;p38 MAPK pathway#P05918>MKP1#P05922 MONDO|Ensembl=ENSMODG00000039697.1|UniProtKB=A0A5F8H4X2 A0A5F8H4X2 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000038558.1|UniProtKB=A0A5F8H8N6 A0A5F8H8N6 GCLM PTHR13295:SF4 GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT GLUTAMATE--CYSTEINE LIGASE REGULATORY SUBUNIT binding#GO:0005488;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function regulator activity#GO:0098772 peptide metabolic process#GO:0006518;biosynthetic process#GO:0009058;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262;ligase#PC00142 MONDO|Ensembl=ENSMODG00000018574.4|UniProtKB=F7FRE2 F7FRE2 PTHR10676:SF359 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN DOMAIN-CONTAINING PROTEIN 1 macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule motor activity#GO:0003777;protein binding#GO:0005515 microtubule-based process#GO:0007017;cilium-dependent cell motility#GO:0060285;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294 intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;dynein complex#GO:0030286;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729;catalytic complex#GO:1902494 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000042716.1|UniProtKB=F7A2H8 F7A2H8 LOC100028415 PTHR26451:SF210 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000005191.4|UniProtKB=F6XG12 F6XG12 MNX1 PTHR24335:SF3 MOTOR NEURON AND PANCREAS HOMEOBOX PROTEIN MOTOR NEURON AND PANCREAS HOMEOBOX PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 neuron fate commitment#GO:0048663;cellular process#GO:0009987;epithelium development#GO:0060429;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;nervous system development#GO:0007399;neuron differentiation#GO:0030182;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;cell fate specification#GO:0001708;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;animal organ development#GO:0048513;neurogenesis#GO:0022008;pancreas development#GO:0031016;cell differentiation#GO:0030154;central nervous system development#GO:0007417;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;cell fate commitment#GO:0045165;system development#GO:0048731 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000019482.3|UniProtKB=F6WAC3 F6WAC3 DUSP15 PTHR45948:SF4 DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0269404-RELATED DUAL SPECIFICITY PROTEIN PHOSPHATASE 15 protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;signaling#GO:0023052;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of MAPK cascade#GO:0043410;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000003543.3|UniProtKB=A0A5F8GPR1 A0A5F8GPR1 SCRG1 PTHR17463:SF0 SCRAPIE-RESPONSIVE PROTEIN 1 SCRG1 SCRAPIE-RESPONSIVE PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;neuron projection terminus#GO:0044306;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 MONDO|Ensembl=ENSMODG00000004538.3|UniProtKB=F6U947 F6U947 BTBD2 PTHR45774:SF6 BTB/POZ DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN 2 cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;system development#GO:0048731;neurogenesis#GO:0022008;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000023336.3|UniProtKB=F7AH70 F7AH70 PTHR11588:SF251 TUBULIN TUBULIN ALPHA-1B CHAIN anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553 nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;cellular process#GO:0009987;organelle organization#GO:0006996;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell differentiation#GO:0030154;mitotic cell cycle#GO:0000278;cellular component organization#GO:0016043;cell cycle#GO:0007049;system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;tubulin#PC00228 Gonadotropin-releasing hormone receptor pathway#P06664>Tubulin#P06772 MONDO|Ensembl=ENSMODG00000012190.4|UniProtKB=F7CEJ6 F7CEJ6 SAR1A PTHR45684:SF6 RE74312P SMALL COPII COAT GTPASE SAR1A hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;membrane organization#GO:0061024;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;COPII-coated vesicle budding#GO:0090114;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;coated membrane#GO:0048475;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 MONDO|Ensembl=ENSMODG00000014848.4|UniProtKB=F7BZ22 F7BZ22 AKAP11 PTHR10226:SF3 A KINASE ANCHOR PROTEIN A-KINASE ANCHOR PROTEIN 11 protein binding#GO:0005515;binding#GO:0005488;protein kinase A binding#GO:0051018 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;macromolecule localization#GO:0033036;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;intracellular protein localization#GO:0008104;enzyme-linked receptor protein signaling pathway#GO:0007167;localization#GO:0051179;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000042490.1|UniProtKB=A0A5F8GYP9 A0A5F8GYP9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000020517.4|UniProtKB=H9H7L4 H9H7L4 SLC9A6 PTHR10110:SF94 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 6 metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079 regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;recycling endosome#GO:0055037;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000009282.4|UniProtKB=F7CR46 F7CR46 ULK3 PTHR24348:SF65 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE ULK3 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;regulation of catabolic process#GO:0009894;autophagosome assembly#GO:0000045;response to nutrient levels#GO:0031667;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;reticulophagy#GO:0061709;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component assembly#GO:0022607;biological regulation#GO:0065007;macroautophagy#GO:0016236;organelle assembly#GO:0070925;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;regulation of autophagy#GO:0010506;response to starvation#GO:0042594;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;catabolic process#GO:0009056;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;piecemeal microautophagy of the nucleus#GO:0034727 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;autophagosome#GO:0005776;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane#GO:0016020;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000009440.4|UniProtKB=F7AYR0 F7AYR0 MALRD1 PTHR23282:SF140 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM AND LDL-RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000003706.4|UniProtKB=A0A5F8GIE6 A0A5F8GIE6 AOC1 PTHR10638:SF3 COPPER AMINE OXIDASE DIAMINE OXIDASE [COPPER-CONTAINING] metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;oxidoreductase activity#GO:0016491;copper ion binding#GO:0005507;catalytic activity#GO:0003824 biogenic amine metabolic process#GO:0006576;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;amine metabolic process#GO:0009308;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 oxidoreductase#PC00176;oxidase#PC00175 Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103 MONDO|Ensembl=ENSMODG00000012526.4|UniProtKB=F6PZV9 F6PZV9 TBX21 PTHR11267:SF125 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX21 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 mononuclear cell migration#GO:0071674;immune system process#GO:0002376;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;leukocyte migration#GO:0050900;cell fate specification#GO:0001708;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;lymphocyte migration#GO:0072676;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cell migration#GO:0016477;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 MONDO|Ensembl=ENSMODG00000018895.4|UniProtKB=F7CQS2 F7CQS2 AFG2A PTHR23077:SF27 AAA-FAMILY ATPASE ATPASE FAMILY GENE 2 PROTEIN HOMOLOG A hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000018977.4|UniProtKB=F7FPB2 F7FPB2 CRIP3 PTHR46074:SF4 CYSTEINE-RICH PROTEIN CRIP FAMILY MEMBER CYSTEINE-RICH PROTEIN 3 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000005093.4|UniProtKB=F6ZEH9 F6ZEH9 PTHR24253:SF146 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 12 catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000011880.4|UniProtKB=F7G2Q0 F7G2Q0 RASGEF1B PTHR23113:SF197 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1B molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000048718.1|UniProtKB=A0A5F8G648 A0A5F8G648 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000025395.3|UniProtKB=F7GG45 F7GG45 TMEM164 PTHR20948:SF5 TRANSMEMBRANE PROTEIN 164 TRANSMEMBRANE PROTEIN 164 regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068 MONDO|Ensembl=ENSMODG00000016303.4|UniProtKB=F7ATD3 F7ATD3 LCMT1 PTHR13600:SF33 LEUCINE CARBOXYL METHYLTRANSFERASE LEUCINE CARBOXYL METHYLTRANSFERASE 1 O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741 regulation of mitotic cell cycle phase transition#GO:1901990;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of sister chromatid segregation#GO:0033045;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;regulation of cell cycle phase transition#GO:1901987;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;regulation of response to stimulus#GO:0048583;regulation of chromosome segregation#GO:0051983;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of chromosome separation#GO:1905818;regulation of nuclear division#GO:0051783;regulation of cell cycle process#GO:0010564;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000022958.2|UniProtKB=F6RH51 F6RH51 PTHR10969:SF110 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GABA TYPE A RECEPTOR ASSOCIATED PROTEIN LIKE 1 GABA receptor binding#GO:0050811;phospholipid binding#GO:0005543;ubiquitin-like protein ligase binding#GO:0044389;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;signaling receptor binding#GO:0005102;enzyme binding#GO:0019899;protein binding#GO:0005515;lipid binding#GO:0008289 cellular component assembly#GO:0022607;macroautophagy#GO:0016236;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;organelle organization#GO:0006996;response to stress#GO:0006950;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;cellular response to nutrient levels#GO:0031669;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;response to starvation#GO:0042594;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;cellular component disassembly#GO:0022411;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;organelle assembly#GO:0070925;cellular response to stress#GO:0033554 autophagosome#GO:0005776;intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000019350.3|UniProtKB=K7E629 K7E629 UNG PTHR11264:SF0 URACIL-DNA GLYCOSYLASE URACIL-DNA GLYCOSYLASE DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;base-excision repair#GO:0006284;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 DNA glycosylase#PC00010 MONDO|Ensembl=ENSMODG00000045260.1|UniProtKB=A0A5F8G3F8 A0A5F8G3F8 PTHR24249:SF78 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 7A-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000023301.2|UniProtKB=F6VBW3 F6VBW3 PTHR11482:SF57 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE GENE MODEL 853, (NCBI) catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;ornithine decarboxylase activity#GO:0004586 negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of biological process#GO:0048519;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;polyamine metabolic process#GO:0006595;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of catabolic process#GO:0009894;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;polyamine biosynthetic process#GO:0006596;negative regulation of protein catabolic process#GO:0042177;biogenic amine metabolic process#GO:0006576;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of primary metabolic process#GO:0080090;amine metabolic process#GO:0009308;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 MONDO|Ensembl=ENSMODG00000016895.2|UniProtKB=F6XII5 F6XII5 GNG13 PTHR15936:SF2 GUANINE NUCLEOTIDE-BINDING PROTEIN G I /G S /G O GAMMA-13 SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-13 protein binding#GO:0005515;binding#GO:0005488 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 catalytic complex#GO:1902494;cytoplasmic side of membrane#GO:0098562;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 G-protein#PC00020;heterotrimeric G-protein#PC00117;protein-binding activity modulator#PC00095 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Wnt signaling pathway#P00057>Ggamma#P01465 MONDO|Ensembl=ENSMODG00000003287.2|UniProtKB=F7EG90 F7EG90 LOC100027752 PTHR10395:SF11 URICASE AND TRANSTHYRETIN-RELATED 5-HYDROXYISOURATE HYDROLASE purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000010540.3|UniProtKB=F6ZEU3 F6ZEU3 PTHR19441:SF27 WAP four-disulfide core domain protein WHEY ACIDIC PROTEIN peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000038369.1|UniProtKB=A0A5F8GRI2 A0A5F8GRI2 PTHR11904:SF12 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 organophosphate biosynthetic process#GO:0090407;purine nucleoside metabolic process#GO:0042278;pyridine-containing compound metabolic process#GO:0072524;nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;glycosyl compound catabolic process#GO:1901658;NAD+ metabolic process#GO:0019674;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;nucleotide metabolic process#GO:0009117;nucleoside catabolic process#GO:0009164;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule catabolic process#GO:0034656;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine-containing compound catabolic process#GO:0072523;purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 kinase#PC00137;nucleotide kinase#PC00172 Xanthine and guanine salvage pathway#P02788>Guanosine phosphorylase#P03250;Adenine and hypoxanthine salvage pathway#P02723>Deoxyinosine phosphorylase#P02812;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphorylase#P02805;Purine metabolism#P02769>Nucleoside Phosphorylase#P03115;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine phosphorylase#P02808;Adenine and hypoxanthine salvage pathway#P02723>Inosine phosphorylase#P02813;Xanthine and guanine salvage pathway#P02788>Deoxyguanosine phosphorylase#P03248 MONDO|Ensembl=ENSMODG00000013429.4|UniProtKB=F7C514 F7C514 NFKBIB PTHR47303:SF1 FAMILY NOT NAMED NF-KAPPA-B INHIBITOR BETA response to other organism#GO:0051707;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;response to external stimulus#GO:0009605;response to lipopolysaccharide#GO:0032496;cellular response to molecule of bacterial origin#GO:0071219;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to molecule of bacterial origin#GO:0002237;cellular response to biotic stimulus#GO:0071216;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to bacterium#GO:0009617 MONDO|Ensembl=ENSMODG00000043570.1|UniProtKB=A0A5F8GBP3 A0A5F8GBP3 PTHR13393:SF0 SAM-DEPENDENT METHYLTRANSFERASE RNA N(6)-ADENOSINE-METHYLTRANSFERASE METTL16 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098 regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;post-transcriptional regulation of gene expression#GO:0010608;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000018844.3|UniProtKB=F7DWI1 F7DWI1 PTHR10334:SF614 CYSTEINE-RICH SECRETORY PROTEIN-RELATED SHKT DOMAIN-CONTAINING PROTEIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000016198.4|UniProtKB=A0A5F8H1R1 A0A5F8H1R1 PABPC1L PTHR24012:SF466 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;poly(A) binding#GO:0008143;mRNA binding#GO:0003729;single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytosol#GO:0005829;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000009389.4|UniProtKB=F7CPG0 F7CPG0 PTHR11477:SF1 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 1 transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000036480.1|UniProtKB=A0A5F8G882 A0A5F8G882 RPL12 PTHR11661:SF2 60S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN UL11 nucleic acid binding#GO:0003676;binding#GO:0005488;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000000459.4|UniProtKB=F6US13 F6US13 NAV1 PTHR12784:SF3 STEERIN NEURON NAVIGATOR 1 animal gross anatomical part developmental process#GO:0160108;microtubule bundle formation#GO:0001578;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;system development#GO:0048731;cellular component organization#GO:0016043;cell motility#GO:0048870;cell differentiation#GO:0030154;developmental process#GO:0032502;cellular developmental process#GO:0048869;neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;neurogenesis#GO:0022008;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell migration#GO:0016477;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;axon#GO:0030424;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;microtubule cytoskeleton#GO:0015630;main axon#GO:0044304;neuron projection#GO:0043005 MONDO|Ensembl=ENSMODG00000019487.4|UniProtKB=F6WA95 F6WA95 DHX29 PTHR18934:SF264 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX29 isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000012915.4|UniProtKB=F7GCE9 F7GCE9 ORMDL3 PTHR12665:SF11 ORMDL PROTEINS ORM1-LIKE PROTEIN 3 sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;ceramide metabolic process#GO:0006672;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;cellular process#GO:0009987;homeostatic process#GO:0042592 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000004360.4|UniProtKB=A0A5F8GU50 A0A5F8GU50 MYH11 PTHR45615:SF23 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-11 isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544 actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522 MONDO|Ensembl=ENSMODG00000015061.4|UniProtKB=F7FHN6 F7FHN6 PTHR23347:SF5 COLORECTAL MUTANT CANCER PROTEIN MCC PROTEIN -RELATED HARMONIN-BINDING PROTEIN USHBP1 MONDO|Ensembl=ENSMODG00000006682.2|UniProtKB=F7FFK1 F7FFK1 RPL38 PTHR10965:SF0 60S RIBOSOMAL PROTEIN L38 LARGE RIBOSOMAL SUBUNIT PROTEIN EL38 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000048110.1|UniProtKB=A0A5F8GER1 A0A5F8GER1 SUPT4H1 PTHR12882:SF1 SUPPRESSOR OF TY 4 TRANSCRIPTION ELONGATION FACTOR SPT4 binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000021498.4|UniProtKB=F7G2R7 F7G2R7 NPC1 PTHR45727:SF11 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934;alcohol binding#GO:0043178;cholesterol binding#GO:0015485;steroid binding#GO:0005496;lipid binding#GO:0008289 transport#GO:0006810;chemical homeostasis#GO:0048878;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;system process#GO:0003008;localization#GO:0051179;sterol transport#GO:0015918;establishment of localization#GO:0051234;cholesterol homeostasis#GO:0042632;macromolecule localization#GO:0033036;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;digestion#GO:0007586;lipid transport#GO:0006869;multicellular organismal process#GO:0032501 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000006151.5|UniProtKB=F7GCL0 F7GCL0 COQ8A PTHR43851:SF1 FAMILY NOT NAMED ATYPICAL KINASE COQ8A, MITOCHONDRIAL biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;ketone metabolic process#GO:0042180;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152 MONDO|Ensembl=ENSMODG00000010145.4|UniProtKB=A0A5F8GCT4 A0A5F8GCT4 POSTN PTHR10900:SF12 PERIOSTIN-RELATED PERIOSTIN protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;homophilic cell-cell adhesion#GO:0007156;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cell adhesion#GO:0007155;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000047098.1|UniProtKB=A0A5F8H0K1 A0A5F8H0K1 LOC100019278 PTHR48002:SF76 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C11 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016994.4|UniProtKB=F6QFD5 F6QFD5 SYT11 PTHR10024:SF115 SYNAPTOTAGMIN SYNAPTOTAGMIN-11 protein binding#GO:0005515;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;SNARE binding#GO:0000149 regulated exocytosis#GO:0045055;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;regulation of transport#GO:0051049;positive regulation of vesicle fusion#GO:0031340;exocytosis#GO:0006887;regulation of localization#GO:0032879;synaptic signaling#GO:0099536;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;synaptic vesicle exocytosis#GO:0016079;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;neurotransmitter transport#GO:0006836;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;export from cell#GO:0140352;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;membrane fusion#GO:0061025;positive regulation of cellular process#GO:0048522;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;regulation of exocytosis#GO:0017157;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;vesicle fusion#GO:0006906 vesicle#GO:0031982;intracellular vesicle#GO:0097708;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;axon#GO:0030424;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell junction#GO:0030054 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 MONDO|Ensembl=ENSMODG00000010015.4|UniProtKB=F7F2T0 F7F2T0 PDHX PTHR23151:SF92 DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED PYRUVATE DEHYDROGENASE PROTEIN X COMPONENT, MITOCHONDRIAL oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227 acetyltransferase#PC00038;transferase#PC00220 MONDO|Ensembl=ENSMODG00000022962.3|UniProtKB=F6VY22 F6VY22 LOC100024810 PTHR11588:SF6 TUBULIN TUBULIN DELTA CHAIN purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 tubulin#PC00228;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000011938.6|UniProtKB=A0A5F8G814 A0A5F8G814 ROCK2 PTHR22988:SF28 MYOTONIC DYSTROPHY S/T KINASE-RELATED RHO-ASSOCIATED PROTEIN KINASE 2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cortical cytoskeleton organization#GO:0030865;regulation of cell junction assembly#GO:1901888;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;cell communication#GO:0007154;cortical actin cytoskeleton organization#GO:0030866;intracellular signal transduction#GO:0035556;cell cycle#GO:0007049;cell division#GO:0051301;cellular response to stimulus#GO:0051716;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;mitotic cell cycle process#GO:1903047;multicellular organismal process#GO:0032501;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cytokinesis#GO:0000910;Rho protein signal transduction#GO:0007266;cytoskeleton-dependent cytokinesis#GO:0061640;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;actomyosin structure organization#GO:0031032;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of actin cytoskeleton organization#GO:0032956;intracellular signaling cassette#GO:0141124;embryo development#GO:0009790;cytoskeleton organization#GO:0007010 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-receptor serine/threonine protein kinase#PC00167 Cytoskeletal regulation by Rho GTPase#P00016>ROCK#P00519 MONDO|Ensembl=ENSMODG00000023357.3|UniProtKB=F6Y404 F6Y404 CRYBG1 PTHR11818:SF2 BETA/GAMMA CRYSTALLIN BETA_GAMMA CRYSTALLIN DOMAIN-CONTAINING PROTEIN 1 structural molecule activity#GO:0005198 lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423;system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000045148.1|UniProtKB=A0A5F8HHA5 A0A5F8HHA5 LOC100028561 PTHR26452:SF977 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019279.4|UniProtKB=F6SHD5 F6SHD5 SLCO4C1 PTHR11388:SF160 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 transporter#PC00227 MONDO|Ensembl=ENSMODG00000015257.4|UniProtKB=F6U368 F6U368 CIT PTHR22988:SF71 MYOTONIC DYSTROPHY S/T KINASE-RELATED CITRON RHO-INTERACTING KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;actin filament-based process#GO:0030029;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;cellular component organization#GO:0016043;cell cycle#GO:0007049;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000024296.2|UniProtKB=F7F0L3 F7F0L3 PTHR48018:SF85 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M10 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018717.4|UniProtKB=F7FBZ3 F7FBZ3 CHD1L PTHR47157:SF1 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1-LIKE ATP-DEPENDENT CHROMATIN REMODELER CHD1L nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363 chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to stress#GO:0006950;cellular component organization or biogenesis#GO:0071840;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000002793.4|UniProtKB=F6YG15 F6YG15 ATP13A2 PTHR45630:SF2 CATION-TRANSPORTING ATPASE-RELATED POLYAMINE-TRANSPORTING ATPASE 13A2 polyamine transmembrane transporter activity#GO:0015203;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;vacuole organization#GO:0007033;regulation of mitochondrion organization#GO:0010821;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;vesicle fusion#GO:0006906;homeostatic process#GO:0042592;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;nitrogen compound transport#GO:0071705;membrane fusion#GO:0061025;macroautophagy#GO:0016236;membrane organization#GO:0061024;biological regulation#GO:0065007;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;process utilizing autophagic mechanism#GO:0061919;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;intracellular monoatomic ion homeostasis#GO:0006873;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;metabolic process#GO:0008152;regulation of anatomical structure size#GO:0090066;chemical homeostasis#GO:0048878;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;organelle organization#GO:0006996;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;late endosome membrane#GO:0031902;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000017631.4|UniProtKB=F6ZSB3 F6ZSB3 RLF PTHR15507:SF18 ZINC FINGER PROTEIN RLF ZINC FINGER PROTEIN RLF transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015250.5|UniProtKB=A0A5F8GXC1 A0A5F8GXC1 POMGNT2 PTHR20961:SF167 GLYCOSYLTRANSFERASE PROTEIN O-LINKED-MANNOSE BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE 2 acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000014645.4|UniProtKB=F6YNU8 F6YNU8 NRF1 PTHR20338:SF8 NUCLEAR RESPIRATORY FACTOR 1 NUCLEAR RESPIRATORY FACTOR 1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000006730.5|UniProtKB=F7CX48 F7CX48 UMOD PTHR14002:SF40 ENDOGLIN/TGF-BETA RECEPTOR TYPE III UROMODULIN cellular process#GO:0009987;neutrophil migration#GO:1990266;cell migration#GO:0016477;granulocyte migration#GO:0097530;cell motility#GO:0048870;leukocyte migration#GO:0050900;immune system process#GO:0002376;myeloid leukocyte migration#GO:0097529 plasma membrane#GO:0005886;cell surface#GO:0009986;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045145.1|UniProtKB=A0A5F8GBN9 A0A5F8GBN9 LOC100011187 PTHR10666:SF424 UBIQUITIN UBIQUITIN-RIBOSOMAL PROTEIN EL40 FUSION PROTEIN structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;nucleus#GO:0005634;cytosol#GO:0005829;cytosolic ribosome#GO:0022626 MONDO|Ensembl=ENSMODG00000028539.2|UniProtKB=A0A5F8H5Q8 A0A5F8H5Q8 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000007630.3|UniProtKB=F7BKN8 F7BKN8 CHST13 PTHR12137:SF60 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 13 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 transferase#PC00220 MONDO|Ensembl=ENSMODG00000024868.2|UniProtKB=F6YV86 F6YV86 PTHR45883:SF2 HSC70-INTERACTING PROTEIN HSC70-INTERACTING PROTEIN protein binding#GO:0005515;Hsp70 protein binding#GO:0030544;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;heat shock protein binding#GO:0031072 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 MONDO|Ensembl=ENSMODG00000049203.1|UniProtKB=A0A5F8HAT5 A0A5F8HAT5 COX17 PTHR16719:SF0 CYTOCHROME C OXIDASE COPPER CHAPERONE CYTOCHROME C OXIDASE COPPER CHAPERONE molecular carrier activity#GO:0140104 mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000003026.4|UniProtKB=A0A5F8GEI4 A0A5F8GEI4 MYBPC1 PTHR13817:SF27 TITIN MYOSIN-BINDING PROTEIN C, SLOW-TYPE structural molecule activity#GO:0005198 muscle cell development#GO:0055001;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;actomyosin structure organization#GO:0031032;cell development#GO:0048468;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146 M band#GO:0031430;intracellular organelle#GO:0043229;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;A band#GO:0031672;contractile muscle fiber#GO:0043292;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000010560.4|UniProtKB=F6YR75 F6YR75 PTHR24221:SF237 ATP-BINDING CASSETTE SUB-FAMILY B ANTIGEN PEPTIDE TRANSPORTER 2 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000000215.3|UniProtKB=F6SZL7 F6SZL7 PPP1R14D PTHR16188:SF13 PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14D molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein serine/threonine phosphatase inhibitor activity#GO:0004865 phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000016459.4|UniProtKB=H9H6V1 H9H6V1 TAC1 PTHR11250:SF0 TACHYKININ TACHYKININ 1 MONDO|Ensembl=ENSMODG00000027962.2|UniProtKB=K7E0A3 K7E0A3 LOC100012228 PTHR24197:SF51 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 61 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 54 kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000012452.3|UniProtKB=F6PI08 F6PI08 SP2 PTHR23235:SF1 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP2 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000021444.4|UniProtKB=A0A5F8H0P2 A0A5F8H0P2 PPP4R1 PTHR10648:SF8 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase modulator#PC00184 FGF signaling pathway#P00021>PP2A#P00629 MONDO|Ensembl=ENSMODG00000019262.4|UniProtKB=F6Q8L1 F6Q8L1 BMPR1B PTHR23255:SF62 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1B transmembrane signaling receptor activity#GO:0004888;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;molecular transducer activity#GO:0060089;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transforming growth factor beta receptor activity#GO:0005024;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096 cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;response to BMP#GO:0071772;multicellular organismal process#GO:0032501;regionalization#GO:0003002;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;dorsal/ventral pattern formation#GO:0009953 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>BMPR-IA/IB/II#P06740;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442 MONDO|Ensembl=ENSMODG00000010683.3|UniProtKB=F7C160 F7C160 CD83 PTHR15193:SF1 CD83 ANTIGEN CD83 ANTIGEN MONDO|Ensembl=ENSMODG00000045338.1|UniProtKB=A0A5F8G7U9 A0A5F8G7U9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016579.4|UniProtKB=F7D3B5 F7D3B5 OAT PTHR11986:SF126 AMINOTRANSFERASE CLASS III ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL transaminase activity#GO:0008483;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;arginine metabolic process#GO:0006525;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transaminase#PC00216 MONDO|Ensembl=ENSMODG00000014672.4|UniProtKB=F7F2V3 F7F2V3 PTHR23420:SF2 ADENOSYLHOMOCYSTEINASE S-ADENOSYLHOMOCYSTEINE HYDROLASE-LIKE PROTEIN 2 catalytic activity#GO:0003824;hydrolase activity#GO:0016787 purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;purine-containing compound metabolic process#GO:0072521;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;sulfur compound metabolic process#GO:0006790 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000018117.4|UniProtKB=F7F1Z4 F7F1Z4 LOC103097545 PTHR31156:SF14 WBSCR19-LIKE PROTEIN SPEEDY_RINGO CELL CYCLE REGULATOR FAMILY, MEMBER E4C MONDO|Ensembl=ENSMODG00000048670.1|UniProtKB=A0A5F8G801 A0A5F8G801 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000006411.3|UniProtKB=F7FD88 F7FD88 LOC100013449 PTHR26453:SF17 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000029563.2|UniProtKB=K7E5S2 K7E5S2 LOC100026811 PTHR11961:SF6 CYTOCHROME C CYTOCHROME C, TESTIS-SPECIFIC electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739 Apoptosis signaling pathway#P00006>Cytochrome C#P00322 MONDO|Ensembl=ENSMODG00000008976.4|UniProtKB=F7FRM5 F7FRM5 PPP2R5E PTHR10257:SF92 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT EPSILON ISOFORM enzyme activator activity#GO:0008047;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;protein phosphatase regulator activity#GO:0019888;phosphatase activator activity#GO:0019211 cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;meiotic sister chromatid cohesion#GO:0051177 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;protein phosphatase#PC00195 FGF signaling pathway#P00021>PP2A#P00629;Wnt signaling pathway#P00057>PP2A#P01438;EGF receptor signaling pathway#P00018>PP2A#P00547 MONDO|Ensembl=ENSMODG00000013640.3|UniProtKB=F6UE48 F6UE48 PTHR15223:SF1 NADH-UBIQUINONE OXIDOREDUCTASE AGGG SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2, MITOCHONDRIAL generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000010000.4|UniProtKB=F6US84 F6US84 RASSF4 PTHR22738:SF4 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 4 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000044614.1|UniProtKB=A0A5F8G2A3 A0A5F8G2A3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000001022.3|UniProtKB=F6ZFE5 F6ZFE5 LRG1 PTHR45617:SF101 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH ALPHA-2-GLYCOPROTEIN signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;protein binding#GO:0005515 anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;regulation of angiogenesis#GO:0045765;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell motility#GO:0048870;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of vasculature development#GO:1901342;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;tissue development#GO:0009888;cell migration#GO:0016477;epithelium development#GO:0060429;positive regulation of response to stimulus#GO:0048584;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to wounding#GO:0009611;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;wound healing#GO:0042060;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;positive regulation of angiogenesis#GO:0045766;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of anatomical structure morphogenesis#GO:0022603;morphogenesis of an epithelium#GO:0002009;regulation of multicellular organismal process#GO:0051239;response to stress#GO:0006950;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020867.4|UniProtKB=F6QG81 F6QG81 LOC130453961 PTHR44427:SF1 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CELL ADHESION MOLECULE CEACAM1 binding#GO:0005488;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000010137.3|UniProtKB=F6WMZ8 F6WMZ8 POU4F3 PTHR11636:SF43 POU DOMAIN POU DOMAIN, CLASS 4, TRANSCRIPTION FACTOR 3 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000021019.4|UniProtKB=F6QZB8 F6QZB8 PTHR13826:SF18 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 1 system process#GO:0003008;tissue homeostasis#GO:0001894;multicellular organismal-level homeostasis#GO:0048871;digestion#GO:0007586;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;epithelial structure maintenance#GO:0010669;homeostatic process#GO:0042592 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 CCKR signaling map#P06959>TFF1#G07287;CCKR signaling map#P06959>TFF1#G06993 MONDO|Ensembl=ENSMODG00000015321.4|UniProtKB=F6XXK5 F6XXK5 CHN2 PTHR46075:SF4 CHIMERIN FAMILY MEMBER BETA-CHIMAERIN molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endomembrane system organization#GO:0010256;male gamete generation#GO:0048232;cellular component assembly#GO:0022607;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular anatomical entity morphogenesis#GO:0032989;vesicle organization#GO:0016050;anatomical structure formation involved in morphogenesis#GO:0048646;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;germ cell development#GO:0007281;anatomical structure morphogenesis#GO:0009653;developmental process involved in reproduction#GO:0003006;cellular component organization#GO:0016043;reproductive process#GO:0022414;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell differentiation#GO:0030154;spermatid development#GO:0007286;acrosome assembly#GO:0001675;sexual reproduction#GO:0019953;cellular component assembly involved in morphogenesis#GO:0010927;spermatid differentiation#GO:0048515;organelle assembly#GO:0070925;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856 MONDO|Ensembl=ENSMODG00000019329.4|UniProtKB=F6XST2 F6XST2 TAOK1 PTHR48015:SF31 SERINE/THREONINE-PROTEIN KINASE TAO NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000024341.2|UniProtKB=F7A7S4 F7A7S4 LOC100022446 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017273.4|UniProtKB=A0A5F8GVE8 A0A5F8GVE8 ADGRG6 PTHR12011:SF290 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G6 G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;extracellular matrix binding#GO:0050840;molecular transducer activity#GO:0060089;protein binding#GO:0005515;binding#GO:0005488;laminin binding#GO:0043236;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;multicellular organism development#GO:0007275;animal organ development#GO:0048513;gliogenesis#GO:0042063;myelination#GO:0042552;anatomical structure formation involved in morphogenesis#GO:0048646;signal transduction#GO:0007165;cellular process#GO:0009987;heart development#GO:0007507;nervous system development#GO:0007399;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;peripheral nervous system development#GO:0007422;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cell differentiation#GO:0030154;signaling#GO:0023052;cell development#GO:0048468;developmental process#GO:0032502;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;heart morphogenesis#GO:0003007;cellular response to stimulus#GO:0051716;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004862.4|UniProtKB=A0A5F8G9W8 A0A5F8G9W8 SRRT PTHR13165:SF0 ARSENITE-RESISTANCE PROTEIN 2 SERRATE RNA EFFECTOR MOLECULE HOMOLOG RNA binding#GO:0003723;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;nucleic acid binding#GO:0003676 primary miRNA processing#GO:0031053;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 MONDO|Ensembl=ENSMODG00000016168.4|UniProtKB=F7G8R2 F7G8R2 MYL7 PTHR23049:SF39 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 2, ATRIAL ISOFORM myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 multicellular organismal process#GO:0032501;tissue development#GO:0009888;heart development#GO:0007507;blood circulation#GO:0008015;cardiac muscle tissue development#GO:0048738;animal organ development#GO:0048513;multicellular organism development#GO:0007275;heart contraction#GO:0060047;system process#GO:0003008;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;circulatory system development#GO:0072359;heart process#GO:0003015;anatomical structure development#GO:0048856;system development#GO:0048731;muscle tissue development#GO:0060537;circulatory system process#GO:0003013;animal gross anatomical part developmental process#GO:0160108 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;contractile muscle fiber#GO:0043292;myosin complex#GO:0016459;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000020782.4|UniProtKB=F6YKJ3 F6YKJ3 WDFY3 PTHR46108:SF1 BLUE CHEESE WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 3 process utilizing autophagic mechanism#GO:0061919;macroautophagy#GO:0016236;catabolic process#GO:0009056;cellular process#GO:0009987;autophagy#GO:0006914;metabolic process#GO:0008152 MONDO|Ensembl=ENSMODG00000011773.3|UniProtKB=F7CVZ9 F7CVZ9 PTHR11528:SF125 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN 90 ALPHA FAMILY CLASS A MEMBER 1, PSEUDOGENE 16 small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;ATP-dependent activity#GO:0140657;ATP binding#GO:0005524;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 macromolecule metabolic process#GO:0043170;protein stabilization#GO:0050821;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;biological regulation#GO:0065007;response to temperature stimulus#GO:0009266;response to heat#GO:0009408;cellular response to heat#GO:0034605;response to stress#GO:0006950;regulation of protein stability#GO:0031647;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;protein folding#GO:0006457;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716 cell body#GO:0044297;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;perinuclear region of cytoplasm#GO:0048471;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;myelin sheath#GO:0043209;cytoplasm#GO:0005737 chaperone#PC00072;Hsp90 family chaperone#PC00028 MONDO|Ensembl=ENSMODG00000046838.1|UniProtKB=K7E270 K7E270 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000050457.1|UniProtKB=A0A5F8GIG2 A0A5F8GIG2 TEX30 PTHR13136:SF11 TESTIS DEVELOPMENT PROTEIN PRTD TESTIS-EXPRESSED PROTEIN 30 MONDO|Ensembl=ENSMODG00000006197.3|UniProtKB=F7AHD6 F7AHD6 SEPTIN12 PTHR18884:SF66 SEPTIN SEPTIN-12 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;intracellular protein localization#GO:0008104;cytokinesis#GO:0000910;macromolecule localization#GO:0033036;cell cycle#GO:0007049;cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cell periphery#GO:0071944;cell cortex#GO:0005938;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000011531.3|UniProtKB=F6QXW7 F6QXW7 RAB9B PTHR47981:SF17 RAB FAMILY RAS-RELATED PROTEIN RAB-9B hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 intracellular transport#GO:0046907;phagocytosis#GO:0006909;phagolysosome assembly#GO:0001845;transport#GO:0006810;lytic vacuole organization#GO:0080171;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;endosomal transport#GO:0016197;receptor-mediated endocytosis#GO:0006898;retrograde transport, endosome to Golgi#GO:0042147;membrane fusion#GO:0061025;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;lysosome organization#GO:0007040;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;organelle assembly#GO:0070925;cellular localization#GO:0051641;localization#GO:0051179;vacuole organization#GO:0007033;cellular component organization#GO:0016043;endocytosis#GO:0006897;cytosolic transport#GO:0016482;vesicle fusion#GO:0006906 lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;phagocytic vesicle#GO:0045335;endomembrane system#GO:0012505;late endosome#GO:0005770;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000015485.3|UniProtKB=F6RF16 F6RF16 SUCLG1 PTHR11117:SF2 SUCCINYL-COA LIGASE SUBUNIT ALPHA SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 ligase#PC00142;metabolite interconversion enzyme#PC00262 TCA cycle#P00051>Succinyl CoA Synthetase#P01274 MONDO|Ensembl=ENSMODG00000029228.2|UniProtKB=K7E0X2 K7E0X2 PVALEF PTHR23064:SF29 TROPONIN PARVALBUMIN-LIKE EF-HAND-CONTAINING PROTEIN skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;multicellular organismal process#GO:0032501;muscle system process#GO:0003012;system process#GO:0003008;muscle contraction#GO:0006936;neuromuscular process#GO:0050905;nervous system process#GO:0050877 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;sarcomere#GO:0030017;contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000020104.4|UniProtKB=F7ERZ3 F7ERZ3 SERPING1 PTHR11461:SF159 SERINE PROTEASE INHIBITOR, SERPIN PLASMA PROTEASE C1 INHIBITOR enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000013799.3|UniProtKB=F6TDE0 F6TDE0 LOC100026087 PTHR10078:SF27 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-1 cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;response to other organism#GO:0051707;immune response#GO:0006955;response to external stimulus#GO:0009605;defense response#GO:0006952;cellular response to molecule of bacterial origin#GO:0071219;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;inflammatory response#GO:0006954;response to bacterium#GO:0009617;cytokine-mediated signaling pathway#GO:0019221;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;response to lipopolysaccharide#GO:0032496;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;cellular response to cytokine stimulus#GO:0071345;response to peptide#GO:1901652;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interleukin superfamily#PC00128;cytokine#PC00083;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000013040.4|UniProtKB=A0A5F8G7U0 A0A5F8G7U0 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000050201.1|UniProtKB=A0A5F8G2A1 A0A5F8G2A1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009323.4|UniProtKB=F7GJN8 F7GJN8 ARV1 PTHR14467:SF0 ARV1 PROTEIN ARV1 glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000016000.4|UniProtKB=F7EYY6 F7EYY6 ECE1 PTHR11733:SF130 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED ENDOTHELIN-CONVERTING ENZYME 1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;proteolysis#GO:0006508;hormone metabolic process#GO:0042445;gene expression#GO:0010467;protein maturation#GO:0051604;biological regulation#GO:0065007;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;peptide hormone processing#GO:0016486;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 MONDO|Ensembl=ENSMODG00000016402.4|UniProtKB=F7E8R0 F7E8R0 TRAP1 PTHR11528:SF44 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN 75 KDA, MITOCHONDRIAL-RELATED catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP binding#GO:0005524;kinase binding#GO:0019900;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Hsp90 family chaperone#PC00028;chaperone#PC00072 MONDO|Ensembl=ENSMODG00000008472.4|UniProtKB=F7GEL3 F7GEL3 ACBD5 PTHR23310:SF6 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5 heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579 transfer/carrier protein#PC00219 MONDO|Gene=GH1|UniProtKB=Q9GL60 Q9GL60 GH1 PTHR11417:SF2 SOMATOTROPIN,PROLACTIN SOMATOTROPIN growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;cytokine receptor binding#GO:0005126;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515 regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular response to nitrogen compound#GO:1901699;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cellular response to peptide hormone stimulus#GO:0071375;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;animal organ development#GO:0048513;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;animal gross anatomical part developmental process#GO:0160108;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 MONDO|Ensembl=ENSMODG00000016257.4|UniProtKB=F7C1W8 F7C1W8 PTHR21017:SF19 NIPSNAP-RELATED NIPSNAP HOMOLOG 3A-RELATED protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;autophagy#GO:0006914;macroautophagy#GO:0016236;catabolic process#GO:0009056;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;process utilizing autophagic mechanism#GO:0061919;mitophagy#GO:0000423 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000014139.4|UniProtKB=F6XKN9 F6XKN9 FSTL4 PTHR10913:SF9 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 4 cellular process#GO:0009987;developmental process#GO:0032502;cellular developmental process#GO:0048869;cell differentiation#GO:0030154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000037024.1|UniProtKB=A0A5F8G5W6 A0A5F8G5W6 CABP2 PTHR45917:SF2 CALCIUM-BINDING PROTEIN 1-RELATED CALCIUM-BINDING PROTEIN 2 transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;sensory perception of sound#GO:0007605;response to light stimulus#GO:0009416;visual perception#GO:0007601;signaling#GO:0023052;response to abiotic stimulus#GO:0009628;sensory perception of light stimulus#GO:0050953;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;detection of stimulus#GO:0051606;response to radiation#GO:0009314;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;response to external stimulus#GO:0009605 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000023188.3|UniProtKB=F7FZ24 F7FZ24 LYRM9 PTHR47061:SF1 LYR MOTIF-CONTAINING PROTEIN 9 LYR MOTIF-CONTAINING PROTEIN 9 MONDO|Ensembl=ENSMODG00000012216.4|UniProtKB=A0A5F8HEF2 A0A5F8HEF2 ATP9B PTHR24092:SF50 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IIB-RELATED intramembrane lipid carrier activity#GO:0140303;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 transport#GO:0006810;Golgi vesicle transport#GO:0048193;regulation of membrane lipid distribution#GO:0097035;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;vesicle-mediated transport#GO:0016192;lipid transport#GO:0006869;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular component organization#GO:0016043;lipid translocation#GO:0034204;endocytosis#GO:0006897;organophosphate ester transport#GO:0015748 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000044058.1|UniProtKB=A0A5F8G711 A0A5F8G711 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000050177.1|UniProtKB=A0A5F8H4J7 A0A5F8H4J7 SMIM7 PTHR28622:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 7 SMALL INTEGRAL MEMBRANE PROTEIN 7 MONDO|Ensembl=ENSMODG00000006816.3|UniProtKB=F6PGF8 F6PGF8 CA7 PTHR18952:SF124 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 7 hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000049407.1|UniProtKB=A0A5F8GWW6 A0A5F8GWW6 PTHR11005:SF26 LYSOSOMAL ACID LIPASE-RELATED LYSOSOMAL ACID LIPASE_CHOLESTERYL ESTER HYDROLASE hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 hydrolase#PC00121;lipase#PC00143 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol esterase#P02830 MONDO|Ensembl=ENSMODG00000019231.4|UniProtKB=F6RE45 F6RE45 NLK PTHR24055:SF380 MITOGEN-ACTIVATED PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE NLK protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Nemo-like Kinase#P01449 MONDO|Ensembl=ENSMODG00000005419.4|UniProtKB=F6YK83 F6YK83 MOV10L1 PTHR10887:SF419 DNA2/NAM7 HELICASE FAMILY RNA HELICASE MOV10L1 ISOFORM X1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000010231.4|UniProtKB=F6WRZ1 F6WRZ1 LARS1 PTHR45794:SF1 LEUCYL-TRNA SYNTHETASE LEUCINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000002430.3|UniProtKB=F7E0E0 F7E0E0 TOE1 PTHR15092:SF37 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 TARGET OF EGR1 PROTEIN 1 RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;RNA binding#GO:0003723;snRNA binding#GO:0017069;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;nucleic acid binding#GO:0003676;binding#GO:0005488;3'-5'-RNA exonuclease activity#GO:0000175 RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000007491.4|UniProtKB=F7CQL3 F7CQL3 GPR152 PTHR11334:SF1 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 152-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017940.3|UniProtKB=F7EJP2 F7EJP2 PDE6H PTHR12122:SF5 RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE GAMMA-SUBUNIT-RELATED RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT GAMMA regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;ciliary membrane#GO:0060170;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cilium#GO:0005929;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cell projection membrane#GO:0031253;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;photoreceptor outer segment#GO:0001750;organelle#GO:0043226 phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000038680.1|UniProtKB=F6TV56 F6TV56 PTHR22848:SF0 WD40 REPEAT PROTEIN WD40 REPEAT-CONTAINING PROTEIN SMU1 macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000018876.4|UniProtKB=F6Z1T7 F6Z1T7 TNFRSF21 PTHR46921:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 21 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 21 regulation of leukocyte proliferation#GO:0070663;negative regulation of T cell proliferation#GO:0042130;humoral immune response#GO:0006959;regulation of B cell proliferation#GO:0030888;negative regulation of cell-cell adhesion#GO:0022408;regulation of T cell activation#GO:0050863;negative regulation of lymphocyte activation#GO:0051250;negative regulation of leukocyte activation#GO:0002695;regulation of multicellular organismal process#GO:0051239;regulation of B cell activation#GO:0050864;regulation of mononuclear cell proliferation#GO:0032944;cellular process#GO:0009987;neuron apoptotic process#GO:0051402;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;apoptotic process#GO:0006915;regulation of multicellular organismal development#GO:2000026;negative regulation of cell activation#GO:0050866;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of system process#GO:0044057;negative regulation of cellular process#GO:0048523;negative regulation of cell adhesion#GO:0007162;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;adaptive immune response#GO:0002250;negative regulation of cell population proliferation#GO:0008285;immune response#GO:0006955;regulation of cell population proliferation#GO:0042127;regulation of nervous system development#GO:0051960;negative regulation of T cell activation#GO:0050868;regulation of T cell proliferation#GO:0042129;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of developmental process#GO:0050793;negative regulation of multicellular organismal process#GO:0051241;programmed cell death#GO:0012501;cell death#GO:0008219 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015132.2|UniProtKB=F7D049 F7D049 IFI35 PTHR15225:SF1 INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN INTERFERON-INDUCED 35 KDA PROTEIN membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000004978.5|UniProtKB=F7FKY3 F7FKY3 EN2 PTHR24341:SF5 HOMEOBOX PROTEIN ENGRAILED HOMEOBOX PROTEIN ENGRAILED-2 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 MONDO|Ensembl=ENSMODG00000036880.1|UniProtKB=A0A5F8GGR7 A0A5F8GGR7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000029678.2|UniProtKB=K7E284 K7E284 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000042627.1|UniProtKB=A0A5F8G6U2 A0A5F8G6U2 RSAD2 PTHR21339:SF0 RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 2 S-ADENOSYLMETHIONINE-DEPENDENT NUCLEOTIDE DEHYDRATASE RSAD2 binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 response to external stimulus#GO:0009605;defense response#GO:0006952;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to virus#GO:0009615;regulation of immune response#GO:0050776;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;defense response to virus#GO:0051607 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000017211.4|UniProtKB=F6XES8 F6XES8 LRRC17 PTHR24373:SF301 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 17 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038289.1|UniProtKB=A0A5F8GDG8 A0A5F8GDG8 PTHR11727:SF13 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE 2, MITOCHONDRIAL catalytic activity, acting on a rRNA#GO:0140102;rRNA (adenine) methyltransferase activity#GO:0016433;transcription regulator activity#GO:0140110;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640 macromolecule biosynthetic process#GO:0009059;mitochondrial transcription#GO:0006390;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;mitochondrial gene expression#GO:0140053;rRNA processing#GO:0006364;mitochondrial RNA metabolic process#GO:0000959;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;rRNA modification#GO:0000154;ribonucleoprotein complex biogenesis#GO:0022613;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;methylation#GO:0032259 mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000020268.3|UniProtKB=F7C1A5 F7C1A5 MRPS30 PTHR13014:SF3 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S30/P52 PRO-APOTOTIC PROTEIN LARGE RIBOSOMAL SUBUNIT PROTEIN ML65 intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000042182.1|UniProtKB=A0A5F8GZ90 A0A5F8GZ90 PTHR33166:SF2 GAG_P30 DOMAIN-CONTAINING PROTEIN CORE SHELL PROTEIN GAG P30 DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000005181.5|UniProtKB=A0A5F8H7Q0 A0A5F8H7Q0 BLTP3B PTHR22774:SF17 CHOREIN N-TERMINAL DOMAIN-CONTAINING PROTEIN BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 3B transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;lipid transfer activity#GO:0120013 cellular localization#GO:0051641;localization#GO:0051179;lipid localization#GO:0010876;cytosolic transport#GO:0016482;cellular component organization#GO:0016043;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;cellular component organization or biogenesis#GO:0071840;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;lipid transport#GO:0006869;membrane organization#GO:0061024;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 MONDO|Ensembl=ENSMODG00000003542.5|UniProtKB=A0A5F8GDB1 A0A5F8GDB1 TUT7 PTHR12271:SF34 POLY A POLYMERASE CID PAP -RELATED TERMINAL URIDYLYLTRANSFERASE 7 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632 nucleotidyltransferase#PC00174 MONDO|Ensembl=ENSMODG00000007163.4|UniProtKB=F6RCW0 F6RCW0 RNF169 PTHR23328:SF2 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF169 acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;chromatin binding#GO:0003682;nucleosome binding#GO:0031491;ubiquitin-protein transferase activity#GO:0004842;protein-containing complex binding#GO:0044877;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromosome#GO:0005694;site of double-strand break#GO:0035861 MONDO|Ensembl=ENSMODG00000014202.3|UniProtKB=F6TQX6 F6TQX6 WDR46 PTHR14085:SF3 WD-REPEAT PROTEIN BING4 WD REPEAT-CONTAINING PROTEIN 46 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684 MONDO|Ensembl=ENSMODG00000001814.4|UniProtKB=F6T5Q5 F6T5Q5 ZNF572 PTHR23226:SF335 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 572 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000027307.2|UniProtKB=K7DZ58 K7DZ58 SKA3 PTHR48118:SF2 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 3 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 3 chromosome segregation#GO:0007059;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278 chromosome#GO:0005694;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;supramolecular fiber#GO:0099512;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;outer kinetochore#GO:0000940 MONDO|Ensembl=ENSMODG00000000981.3|UniProtKB=F7ES59 F7ES59 RHOC PTHR24072:SF100 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOC ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;protein binding#GO:0005515;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787 cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;biological regulation#GO:0065007;cell migration#GO:0016477;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;mitotic cell cycle process#GO:1903047;cellular response to stimulus#GO:0051716;cell division#GO:0051301;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;cell motility#GO:0048870;mitotic cell cycle#GO:0000278;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154 cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 small GTPase#PC00208;G-protein#PC00020 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rho#P00860;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>RhoA#P05938;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507;Angiogenesis#P00005>GTPase#P00254;Integrin signalling pathway#P00034>Rho#P00948;Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Ras Pathway#P04393>Rho#P04578;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoA#P00740;Axon guidance mediated by semaphorins#P00007>Rho#P00341 MONDO|Ensembl=ENSMODG00000029560.2|UniProtKB=K7E1R0 K7E1R0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000047909.1|UniProtKB=A0A5F8G5Z5 A0A5F8G5Z5 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000002688.4|UniProtKB=F7CYC9 F7CYC9 RCOR3 PTHR16089:SF13 REST COREPRESSOR COREST PROTEIN-RELATED REST COREPRESSOR 3 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000041773.1|UniProtKB=A0A5F8G3G6 A0A5F8G3G6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000017305.4|UniProtKB=A0A5F8HCA5 A0A5F8HCA5 SLC25A16 PTHR24089:SF705 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL COENZYME A TRANSPORTER SLC25A16 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000046341.1|UniProtKB=A0A5F8GR55 A0A5F8GR55 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005630.3|UniProtKB=F7CFC9 F7CFC9 PTHR19433:SF72 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA CHAIN MC.7.G5-RELATED response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000020252.4|UniProtKB=A0A5F8H5K0 A0A5F8H5K0 PTHR22804:SF6 AGGRECAN/VERSICAN PROTEOGLYCAN VERSICAN CORE PROTEIN multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;skeletal system development#GO:0001501;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 external encapsulating structure#GO:0030312;membrane#GO:0016020;extracellular matrix#GO:0031012;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;extracellular region#GO:0005576;cell junction#GO:0030054 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000028280.2|UniProtKB=A0A5F8H4R7 A0A5F8H4R7 PTHR24100:SF149 BUTYROPHILIN BG ANTIGEN 1, MHCB REGION-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune system process#GO:0002376;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768 plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000007603.4|UniProtKB=F6UZU4 F6UZU4 ALDH1L1 PTHR11699:SF120 ALDEHYDE DEHYDROGENASE-RELATED CYTOSOLIC 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 tetrahydrofolate metabolic process#GO:0046653;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 MONDO|Ensembl=ENSMODG00000017084.4|UniProtKB=F6V4J7 F6V4J7 ADGRG2 PTHR12011:SF264 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G2 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037980.1|UniProtKB=A0A5F8GXS5 A0A5F8GXS5 PTHR44468:SF3 COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR-RELATED COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homotypic cell-cell adhesion#GO:0034109 basal part of cell#GO:0045178;cellular anatomical structure#GO:0110165;intercalated disc#GO:0014704;anchoring junction#GO:0070161;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cell-cell junction#GO:0005911;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;bicellular tight junction#GO:0005923;apical junction complex#GO:0043296;cell-cell contact zone#GO:0044291;tight junction#GO:0070160;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000007461.3|UniProtKB=F7DAU8 F7DAU8 UCP3 PTHR45618:SF2 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL TRANSPORTER UCP3-RELATED proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324 temperature homeostasis#GO:0001659;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;multicellular organismal-level homeostasis#GO:0048871;response to stress#GO:0006950;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;multicellular organismal process#GO:0032501;regulation of multicellular organismal process#GO:0051239;response to temperature stimulus#GO:0009266;biological regulation#GO:0065007;mitochondrial transmembrane transport#GO:1990542;adaptive thermogenesis#GO:1990845;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;response to abiotic stimulus#GO:0009628;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;response to cold#GO:0009409;mitochondrial transport#GO:0006839;response to stimulus#GO:0050896;homeostatic process#GO:0042592 mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000018418.4|UniProtKB=A0A5F8GM94 A0A5F8GM94 TTK PTHR22974:SF21 MIXED LINEAGE PROTEIN KINASE DUAL SPECIFICITY PROTEIN KINASE TTK protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 negative regulation of cell cycle#GO:0045786;meiotic cell cycle#GO:0051321;negative regulation of chromosome segregation#GO:0051985;negative regulation of mitotic sister chromatid segregation#GO:0033048;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of chromosome separation#GO:1905818;regulation of cell cycle process#GO:0010564;negative regulation of sister chromatid segregation#GO:0033046;cellular process#GO:0009987;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of cell cycle phase transition#GO:1901988;meiotic cell cycle process#GO:1903046;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;regulation of mitotic sister chromatid separation#GO:0010965;mitotic cell cycle process#GO:1903047;regulation of mitotic nuclear division#GO:0007088;negative regulation of chromosome separation#GO:1905819;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of reproductive process#GO:2000241;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;cell communication#GO:0007154;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;negative regulation of chromosome organization#GO:2001251;sexual reproduction#GO:0019953;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841 intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;kinetochore#GO:0000776;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000042039.1|UniProtKB=A0A5F8GN61 A0A5F8GN61 PTHR12482:SF40 LIPASE ROG1-RELATED-RELATED PROTEIN FAM135A hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000042106.1|UniProtKB=A0A5F8HGS3 A0A5F8HGS3 PTHR14759:SF34 STOP PROTEIN MUCIN-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;localization#GO:0051179;cellular localization#GO:0051641;regulation of microtubule-based process#GO:0032886 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;cis-Golgi network#GO:0005801;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;cytoskeleton#GO:0005856;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000005098.4|UniProtKB=F6ZEG2 F6ZEG2 AMOT PTHR14826:SF6 ANGIOMOTIN ANGIOMOTIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell migration#GO:0016477;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;tube development#GO:0035295;developmental process#GO:0032502;regulation of cell migration#GO:0030334;establishment of cell polarity#GO:0030010;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;actin filament-based process#GO:0030029;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;intracellular signal transduction#GO:0035556;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;hippo signaling#GO:0035329;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization#GO:0016043;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;angiogenesis#GO:0001525 intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054;cell-cell junction#GO:0005911;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;bicellular tight junction#GO:0005923;lamellipodium#GO:0030027;cytoplasm#GO:0005737;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000040665.1|UniProtKB=A0A5F8H1Y7 A0A5F8H1Y7 BCL7C PTHR12767:SF10 BCL7 RELATED B-CELL CLL_LYMPHOMA 7 PROTEIN FAMILY MEMBER C response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;ATPase complex#GO:1904949;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000002526.4|UniProtKB=F7B8U0 F7B8U0 PTCH2 PTHR46022:SF3 PROTEIN PATCHED PROTEIN PATCHED HOMOLOG 2 protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000006497.4|UniProtKB=F7EKL7 F7EKL7 KLK7 PTHR24271:SF45 KALLIKREIN-RELATED KALLIKREIN-7 catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000004271.4|UniProtKB=F6U466 F6U466 PTHR24377:SF1029 IP01015P-RELATED ZINC FINGER PROTEIN 135 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000003564.4|UniProtKB=F7G148 F7G148 LIPG PTHR11610:SF13 LIPASE ENDOTHELIAL LIPASE hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000010625.4|UniProtKB=F7DP86 F7DP86 GFOD1 PTHR43818:SF2 BCDNA.GH03377 GLUCOSE-FRUCTOSE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000037365.1|UniProtKB=A0A5F8HCA3 A0A5F8HCA3 PTHR12226:SF3 MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED SOLUTE CARRIER FAMILY 66 MEMBER 3 MONDO|Ensembl=ENSMODG00000013726.5|UniProtKB=F6XQQ4 F6XQQ4 BAX PTHR11256:SF42 BCL-2 RELATED APOPTOSIS REGULATOR BAX channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell death#GO:0008219;mitochondrial fusion#GO:0008053;programmed cell death#GO:0012501;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;positive regulation of neuron apoptotic process#GO:0043525;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;signaling#GO:0023052;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;positive regulation of programmed cell death#GO:0043068;release of cytochrome c from mitochondria#GO:0001836;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;organelle fusion#GO:0048284;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of neuron apoptotic process#GO:0043523;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020 p53 pathway#P00059>BAX#G01581;CCKR signaling map#P06959>BAX#P07159;Huntington disease#P00029>Bax#G01533;Apoptosis signaling pathway#P00006>Bax#P00271 MONDO|Ensembl=ENSMODG00000017532.4|UniProtKB=F7EI61 F7EI61 PTHR24249:SF220 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227 defense response#GO:0006952;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000013099.4|UniProtKB=A0A5F8G851 A0A5F8G851 ATL1 PTHR10751:SF15 GUANYLATE BINDING PROTEIN ATLASTIN-1 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 heterotrimeric G-protein#PC00117;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000000736.6|UniProtKB=A0A5F8HHD8 A0A5F8HHD8 KAT6B PTHR10615:SF73 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT6B chromatin binding#GO:0003682;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;histone acetyltransferase activity#GO:0004402;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;transcription regulator activity#GO:0140110;acetyltransferase activity#GO:0016407;binding#GO:0005488;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;protein N-acetyltransferase activity#GO:0034212 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 p53 pathway#P00059>CBP#P04623 MONDO|Ensembl=ENSMODG00000040922.1|UniProtKB=A0A5F8GMT7 A0A5F8GMT7 PTHR13946:SF16 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11-A transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;transcription by RNA polymerase II#GO:0006366;nucleic acid biosynthetic process#GO:0141187;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 nucleoplasm#GO:0005654;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000013805.4|UniProtKB=F6SXF7 F6SXF7 ATP6V0A4 PTHR11629:SF26 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A 4 binding#GO:0005488;enzyme binding#GO:0019899;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;homeostatic process#GO:0042592;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;monoatomic ion transmembrane transport#GO:0034220;macroautophagy#GO:0016236;biological regulation#GO:0065007;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;proton transmembrane transport#GO:1902600;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;autophagosome maturation#GO:0097352;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;cellular component organization#GO:0016043;intracellular monoatomic ion homeostasis#GO:0006873;transmembrane transport#GO:0055085;cellular component disassembly#GO:0022411;process utilizing autophagic mechanism#GO:0061919;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;autophagy#GO:0006914;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;chemical homeostasis#GO:0048878 transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;apical plasma membrane#GO:0016324;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;brush border#GO:0005903;cell periphery#GO:0071944;cell projection membrane#GO:0031253;ATPase dependent transmembrane transport complex#GO:0098533;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;proton-transporting two-sector ATPase complex#GO:0016469;apical part of cell#GO:0045177;protein-containing complex#GO:0032991;brush border membrane#GO:0031526;cytoplasm#GO:0005737;vacuole#GO:0005773 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000039428.1|UniProtKB=A0A5F8GZ29 A0A5F8GZ29 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016932.4|UniProtKB=F6VMY3 F6VMY3 DCLRE1C PTHR23240:SF37 DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED PROTEIN ARTEMIS catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;damaged DNA binding#GO:0003684;DNA exonuclease activity#GO:0004529;catalytic activity, acting on DNA#GO:0140097;nucleic acid binding#GO:0003676;binding#GO:0005488;exonuclease activity#GO:0004527;DNA binding#GO:0003677;hydrolase activity#GO:0016787;5'-3' exonuclease activity#GO:0008409;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;telomere organization#GO:0032200;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;double-strand break repair#GO:0006302;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;double-strand break repair via nonhomologous end joining#GO:0006303;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259 nucleus#GO:0005634;DNA repair complex#GO:1990391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nonhomologous end joining complex#GO:0070419;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000003585.3|UniProtKB=F7FPY6 F7FPY6 DCAF12 PTHR19860:SF16 DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 12 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000000799.4|UniProtKB=F6RBL0 F6RBL0 CACNG2 PTHR12107:SF1 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857 system process#GO:0003008;transmission of nerve impulse#GO:0019226;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;cellular localization#GO:0051641;cell communication#GO:0007154;localization#GO:0051179;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological quality#GO:0065008;positive regulation of synaptic transmission#GO:0050806;regulation of signaling#GO:0023051;nervous system process#GO:0050877;localization within membrane#GO:0051668;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of biological process#GO:0050789 transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797 voltage-gated ion channel#PC00241;transporter#PC00227;ion channel#PC00133 Ionotropic glutamate receptor pathway#P00037>stargazin#P00998 MONDO|Ensembl=ENSMODG00000017846.4|UniProtKB=F6Z8C6 F6Z8C6 DSE PTHR15532:SF3 FAMILY NOT NAMED DERMATAN-SULFATE EPIMERASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;isomerase activity#GO:0016853 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;cellular process#GO:0009987;chondroitin sulfate proteoglycan metabolic process#GO:0050654;carbohydrate derivative metabolic process#GO:1901135 MONDO|Ensembl=ENSMODG00000028474.2|UniProtKB=K7E266 K7E266 PTHR10414:SF35 ETHANOLAMINEPHOSPHOTRANSFERASE ETHANOLAMINEPHOSPHOTRANSFERASE 1 transferase#PC00220 MONDO|Ensembl=ENSMODG00000002290.4|UniProtKB=F7CC12 F7CC12 MTBP PTHR14382:SF1 MDM2-BINDING PROTEIN MDM2-BINDING PROTEIN regulation of mitotic cell cycle phase transition#GO:1901990;localization#GO:0051179;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;intracellular protein localization#GO:0008104;positive regulation of mitotic cell cycle#GO:0045931;positive regulation of cell cycle G1/S phase transition#GO:1902808;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;positive regulation of cell cycle#GO:0045787;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of mitotic cell cycle#GO:0007346;macromolecule localization#GO:0033036;protein localization to kinetochore#GO:0034501 intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000015903.4|UniProtKB=A0ACM8QB61 A0ACM8QB61 DNASE1L2 PTHR11371:SF29 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE-1-LIKE 2 DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;binding#GO:0005488;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;DNA binding#GO:0003677;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787 DNA catabolic process#GO:0006308;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;nucleobase-containing compound catabolic process#GO:0034655;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 endodeoxyribonuclease#PC00093 MONDO|Ensembl=ENSMODG00000006584.4|UniProtKB=F7B7I3 F7B7I3 ZBTB10 PTHR24414:SF27 F-BOX/KELCH-REPEAT PROTEIN SKIP4 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 10 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000016677.4|UniProtKB=F7E6I1 F7E6I1 SFMBT2 PTHR12247:SF62 POLYCOMB GROUP PROTEIN SCM-LIKE WITH FOUR MBT DOMAINS PROTEIN 2 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000011302.4|UniProtKB=F6W324 F6W324 PLEKHD1 PTHR14383:SF1 SWAP-70 RECOMBINASE PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY D MEMBER 1 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020806.4|UniProtKB=H9H7N4 H9H7N4 DNAJB4 PTHR24078:SF288 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 4 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;protein maturation#GO:0051604;gene expression#GO:0010467;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;metabolic process#GO:0008152;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;protein folding#GO:0006457;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000008683.3|UniProtKB=F6PXT9 F6PXT9 LOC100011118 PTHR31859:SF5 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT DOMAIN 39D biological regulation#GO:0065007;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;lipid homeostasis#GO:0055088;negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cholesterol homeostasis#GO:0042632;chemical homeostasis#GO:0048878;negative regulation of cellular process#GO:0048523;regulation of lipid metabolic process#GO:0019216 MONDO|Ensembl=ENSMODG00000023098.2|UniProtKB=F7EXC4 F7EXC4 PTHR10704:SF40 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 4 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 amino sugar metabolic process#GO:0006040;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 Golgi apparatus subcompartment#GO:0098791;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000046529.1|UniProtKB=A0A5F8GLB7 A0A5F8GLB7 PTHR48582:SF1 NOTCHLESS-LIKE WD40 REPEAT-CONTAINING PROTEIN NOTCHLESS-LIKE WD40 REPEAT-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000017081.4|UniProtKB=F6VKL8 F6VKL8 PCMTD2 PTHR11579:SF2 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 2 O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 methyltransferase#PC00155;transferase#PC00220 MONDO|Ensembl=ENSMODG00000015830.4|UniProtKB=F7FDV3 F7FDV3 ARHGEF26 PTHR12845:SF4 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 26 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of actin filament-based process#GO:0032970 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000008821.3|UniProtKB=A0A5F8GZU0 A0A5F8GZU0 PTHR20531:SF1 N-ALPHA-ACETYLTRANSFERASE 40 N-ALPHA-ACETYLTRANSFERASE 40 protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;N-acetyltransferase activity#GO:0008080 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000007521.4|UniProtKB=F7GJS0 F7GJS0 SOD2 PTHR11404:SF6 SUPEROXIDE DISMUTASE 2 SUPEROXIDE DISMUTASE [MN], MITOCHONDRIAL metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;antioxidant activity#GO:0016209 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000010247.4|UniProtKB=F6W669 F6W669 CYP2E1 PTHR24300:SF356 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2E1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;binding#GO:0005488;tetrapyrrole binding#GO:0046906 olefinic compound metabolic process#GO:0120254;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;icosanoid metabolic process#GO:0006690;response to chemical#GO:0042221;cellular response to xenobiotic stimulus#GO:0071466;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000010208.4|UniProtKB=F6SAE7 F6SAE7 DPP8 PTHR11731:SF98 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE 8 peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000022968.2|UniProtKB=F6UY37 F6UY37 NICN1 PTHR31239:SF2 NICOLIN 1 NICOLIN-1 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000014001.3|UniProtKB=A0A5F8HLE8 A0A5F8HLE8 ADGRG5 PTHR12011:SF326 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G5 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004173.4|UniProtKB=F7BF51 F7BF51 PTHR24376:SF258 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 814 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000007030.1|UniProtKB=F6UFT8 F6UFT8 NDUFA6 PTHR12964:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B14 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 6 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000012215.4|UniProtKB=F7CE16 F7CE16 ZNF652 PTHR24390:SF90 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 652 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005305.5|UniProtKB=F7DM87 F7DM87 EMSY PTHR16500:SF3 BRCA2-INTERACTING TRANSCRIPTIONAL REPRESSOR EMSY BRCA2-INTERACTING TRANSCRIPTIONAL REPRESSOR EMSY intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000007208.4|UniProtKB=K7DZV6 K7DZV6 SAT2 PTHR10545:SF51 DIAMINE N-ACETYLTRANSFERASE THIALYSINE N-EPSILON-ACETYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 transferase#PC00220;acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000018170.4|UniProtKB=A0A5F8G5G8 A0A5F8G5G8 MAP3K7 PTHR46716:SF1 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674 positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;intracellular signaling cassette#GO:0141124;positive regulation of response to stimulus#GO:0048584;JNK cascade#GO:0007254;regulation of signaling#GO:0023051;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MEK#P00864;TGF-beta signaling pathway#P00052>TAK#P01285;Interleukin signaling pathway#P00036>MEK#P00984;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;Gonadotropin-releasing hormone receptor pathway#P06664>TAK1#P06799;p38 MAPK pathway#P05918>TAK1#P06037;Toll receptor signaling pathway#P00054>TAK1#P01370 MONDO|Ensembl=ENSMODG00000001143.3|UniProtKB=F7CKD7 F7CKD7 FBXL3 PTHR10224:SF18 ES1 PROTEIN HOMOLOG, MITOCHONDRIAL F-BOX_LRR-REPEAT PROTEIN 3 MONDO|Ensembl=ENSMODG00000006189.3|UniProtKB=A0A5F8HIQ5 A0A5F8HIQ5 ICMT PTHR12714:SF9 PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000021350.4|UniProtKB=H9H7Z2 H9H7Z2 EEF1AKMT3 PTHR14614:SF5 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN EEF1A LYSINE METHYLTRANSFERASE 3 transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;lysine N-methyltransferase activity#GO:0016278 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000050747.1|UniProtKB=A0A5F8H641 A0A5F8H641 LOC100025184 PTHR44942:SF4 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000015957.4|UniProtKB=F7FRF6 F7FRF6 LOC100030569 PTHR43762:SF8 L-GULONOLACTONE OXIDASE L-GULONOLACTONE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 L-ascorbic acid metabolic process#GO:0019852;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;monosaccharide biosynthetic process#GO:0046364;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 oxidase#PC00175;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000012323.4|UniProtKB=F7E2Z2 F7E2Z2 BOLL PTHR11176:SF10 BOULE-RELATED PROTEIN BOULE-LIKE translation regulator activity#GO:0045182 regulation of RNA stability#GO:0043487;positive regulation of biosynthetic process#GO:0009891;negative regulation of catabolic process#GO:0009895;positive regulation of translation#GO:0045727;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of translational initiation#GO:0006446;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000013975.5|UniProtKB=F6R638 F6R638 NPHS1 PTHR11640:SF136 NEPHRIN NEPHRIN binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000002905.3|UniProtKB=F6PNF4 F6PNF4 PTHR43447:SF61 ALPHA-AMYLASE ALPHA-AMYLASE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 amylase#PC00048 MONDO|Ensembl=ENSMODG00000008508.3|UniProtKB=F7FTE8 F7FTE8 NCAPH PTHR13108:SF9 CONDENSIN COMPLEX SUBUNIT 2 CONDENSIN COMPLEX SUBUNIT 2 chromatin binding#GO:0003682;binding#GO:0005488 mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;nuclear division#GO:0000280;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;organelle fission#GO:0048285;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;chromosome segregation#GO:0007059;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;condensin complex#GO:0000796 MONDO|Ensembl=ENSMODG00000021256.4|UniProtKB=F6TIS2 F6TIS2 CPA3 PTHR11705:SF65 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B MAST CELL CARBOXYPEPTIDASE A catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000017337.3|UniProtKB=F6WVN2 F6WVN2 SCMH1 PTHR12247:SF68 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SCMH1 protein binding#GO:0005515;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000039080.1|UniProtKB=A0A5F8GAT6 A0A5F8GAT6 LOC103098465 PTHR24381:SF476 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 819 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025363.2|UniProtKB=F6SYS9 F6SYS9 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000002699.3|UniProtKB=F7CY37 F7CY37 PTHR19282:SF550 TETRASPANIN TETRASPANIN-10 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013849.2|UniProtKB=F6X635 F6X635 LOC100015788 PTHR12119:SF2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX UBIQUINONE-BINDING PROTEIN QP-C CYTOCHROME B-C1 COMPLEX SUBUNIT 8 metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904 respiratory chain complex III#GO:0045275;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000018552.4|UniProtKB=F7GCR7 F7GCR7 SLC2A13 PTHR48020:SF55 PROTON MYO-INOSITOL COTRANSPORTER PROTON MYO-INOSITOL COTRANSPORTER solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;solute:proton symporter activity#GO:0015295;symporter activity#GO:0015293 cellular process#GO:0009987;transport#GO:0006810;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transporter#PC00227 MONDO|Ensembl=ENSMODG00000015285.4|UniProtKB=F6T6P3 F6T6P3 ANKZF1 PTHR16036:SF2 ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 TRNA ENDONUCLEASE ANKZF1 RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;translational elongation#GO:0006414;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;organelle disassembly#GO:1903008;translation#GO:0006412;protein catabolic process#GO:0030163;protein biosynthetic process#GO:0160307;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;cytoplasmic translation#GO:0002181;rescue of stalled cytosolic ribosome#GO:0072344;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000020577.4|UniProtKB=A0A5F8GUE9 A0A5F8GUE9 SLC30A9 PTHR13414:SF9 HUEL-CATION TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A9, MITOCHONDRIAL zinc ion transport#GO:0006829;monoatomic ion homeostasis#GO:0050801;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 MONDO|Ensembl=ENSMODG00000016621.4|UniProtKB=F6YNC1 F6YNC1 TM7SF3 PTHR15937:SF3 TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3 TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3 negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000028790.2|UniProtKB=K7E3D5 K7E3D5 LOC103103098 PTHR22406:SF5 NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM SLAIN MOTIF-CONTAINING PROTEIN-LIKE regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;regulation of cellular component biogenesis#GO:0044087;cytoplasmic microtubule organization#GO:0031122;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;protein polymerization#GO:0051258;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;microtubule nucleation#GO:0007020;regulation of microtubule polymerization#GO:0031113;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;biological regulation#GO:0065007;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular process#GO:0048522;microtubule polymerization or depolymerization#GO:0031109;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule polymerization#GO:0046785;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of supramolecular fiber organization#GO:1902903;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;regulation of microtubule-based process#GO:0032886 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;microtubule end#GO:1990752;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000027682.2|UniProtKB=K7E1H8 K7E1H8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000038905.1|UniProtKB=A0A5F8G8E4 A0A5F8G8E4 C10orf105 PTHR38325:SF1 MCG55969 GENE, 17455-RELATED MONDO|Ensembl=ENSMODG00000012087.4|UniProtKB=A0A5F8GM38 A0A5F8GM38 PRKACA PTHR24353:SF82 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;renal system process#GO:0003014;cellular process#GO:0009987;renal absorption#GO:0070293;system process#GO:0003008;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transferase complex#GO:1990234 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Nicotine pharmacodynamics pathway#P06587>PRKACA#P06588;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;GABA-B receptor II signaling#P05731>PKA#P05752;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Endothelin signaling pathway#P00019>PKA#P00570;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-c#P00707;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Enkephalin release#P05913>PKA#P05972;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050 MONDO|Ensembl=ENSMODG00000000727.4|UniProtKB=F6W5Z8 F6W5Z8 PTHR10026:SF43 CYCLIN CYCLIN-T2 kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914 positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription elongation#GO:0032784 organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911 kinase modulator#PC00140;kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000019631.4|UniProtKB=F6XPJ5 F6XPJ5 B3GALT9 PTHR11214:SF29 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 9 catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000024858.2|UniProtKB=F7A9N5 F7A9N5 PTHR10114:SF28 60S RIBOSOMAL PROTEIN L36 RPL36 ALTERNATIVE READING FRAME PROTEIN structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000004227.4|UniProtKB=A0A5F8G3S7 A0A5F8G3S7 GALNT13 PTHR11675:SF47 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 13 glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000013369.3|UniProtKB=F7DTK0 F7DTK0 CKS2 PTHR23415:SF48 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT 2 kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209 cell cycle#GO:0007049;mitotic cell cycle phase transition#GO:0044772;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;nucleus#GO:0005634;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006918.4|UniProtKB=A0A5F8G3P1 A0A5F8G3P1 SLC22A1 PTHR24064:SF432 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 2 active transmembrane transporter activity#GO:0022804;quaternary ammonium group transmembrane transporter activity#GO:0015651;transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215 cellular process#GO:0009987;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;transport#GO:0006810;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000010022.4|UniProtKB=A0A5F8H2K4 A0A5F8H2K4 TXNDC5 PTHR45672:SF3 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5 protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000029220.2|UniProtKB=K7E384 K7E384 CCDC192 PTHR38580:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 192 COILED-COIL DOMAIN-CONTAINING PROTEIN 192 MONDO|Ensembl=ENSMODG00000002647.3|UniProtKB=F7DIB7 F7DIB7 LOC100024060 PTHR11937:SF414 ACTIN ACTIN, CYTOPLASMIC 1 protein binding#GO:0005515;structural constituent of synapse#GO:0098918;binding#GO:0005488;kinase binding#GO:0019900;structural constituent of cytoskeleton#GO:0005200;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;structural molecule activity#GO:0005198 cell development#GO:0048468;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cellular process#GO:0009987;axon development#GO:0061564;neuron projection development#GO:0031175;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;developmental process#GO:0032502;neuron differentiation#GO:0030182 cytoskeleton#GO:0005856;transferase complex#GO:1990234;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular protein-containing complex#GO:0140535;membrane#GO:0016020;H4 histone acetyltransferase complex#GO:1902562;catalytic complex#GO:1902494;axon#GO:0030424;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;plasma membrane bounded cell projection#GO:0120025;actin filament#GO:0005884;cell junction#GO:0030054;histone acetyltransferase complex#GO:0000123;chromatin#GO:0000785;neuron projection#GO:0043005;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;acetyltransferase complex#GO:1902493;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;cell projection#GO:0042995 actin and actin related protein#PC00039 Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470 MONDO|Ensembl=ENSMODG00000002742.3|UniProtKB=F6Z6X9 F6Z6X9 LIPH PTHR11610:SF12 LIPASE LIPASE MEMBER H hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;lipase activity#GO:0016298 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 2-arachidonoylglycerol biosynthesis#P05726>PLA1#P05735 MONDO|Ensembl=ENSMODG00000014880.3|UniProtKB=F6YKQ8 F6YKQ8 RPL15 PTHR11847:SF4 RIBOSOMAL PROTEIN L15 LARGE RIBOSOMAL SUBUNIT PROTEIN EL15 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000001036.4|UniProtKB=F6ZEZ4 F6ZEZ4 POLR3A PTHR19376:SF72 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000006063.4|UniProtKB=F7E2V4 F7E2V4 PTHR13318:SF169 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX AND LEUCINE-RICH REPEAT PROTEIN 9 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000027952.1|UniProtKB=K7E0S7 K7E0S7 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000013443.4|UniProtKB=K7DZF6 K7DZF6 GORASP1 PTHR12893:SF2 GOLGI REASSEMBLY STACKING PROTEIN GRASP GOLGI REASSEMBLY-STACKING PROTEIN 1 cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 MONDO|Ensembl=ENSMODG00000008607.3|UniProtKB=F6PHC7 F6PHC7 PTHR21831:SF2 MICROTUBULE-ASSOCIATED PROTEIN 10 MICROTUBULE-ASSOCIATED PROTEIN 10 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;mitotic sister chromatid segregation#GO:0000070;positive regulation of cellular process#GO:0048522;mitotic spindle assembly#GO:0090307;biological regulation#GO:0065007;organelle assembly#GO:0070925;regulation of cell division#GO:0051302;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;regulation of cell cycle process#GO:0010564;spindle elongation#GO:0051231;positive regulation of cell cycle#GO:0045787;regulation of cytokinesis#GO:0032465;nuclear division#GO:0000280;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic spindle organization#GO:0007052;cytoplasmic microtubule organization#GO:0031122;regulation of cell cycle#GO:0051726 spindle pole#GO:0000922;cytoplasmic microtubule#GO:0005881;midbody#GO:0030496;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular organelle#GO:0043229;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;microtubule cytoskeleton#GO:0015630;mitotic spindle pole#GO:0097431;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000040262.1|UniProtKB=A0A5F8HG33 A0A5F8HG33 C11orf96 PTHR40250:SF1 CHROMOSOME 11 OPEN READING FRAME 96 SI:CH1073-281M9.1 MONDO|Ensembl=ENSMODG00000025195.2|UniProtKB=F7C0H1 F7C0H1 PTHR11627:SF1 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE A lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832;fructose-bisphosphate aldolase activity#GO:0004332;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;ADP catabolic process#GO:0046032;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;oxoacid metabolic process#GO:0043436;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide catabolic process#GO:0009166;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;primary metabolic process#GO:0044238;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 lyase#PC00144;aldolase#PC00044 Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959;Glycolysis#P00024>Aldolase#P00679 MONDO|Ensembl=ENSMODG00000010067.4|UniProtKB=H9H6D3 H9H6D3 RPS19 PTHR11710:SF0 40S RIBOSOMAL PROTEIN S19 SMALL RIBOSOMAL SUBUNIT PROTEIN ES19 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467 cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000001139.4|UniProtKB=F7D4N9 F7D4N9 RASGRP1 PTHR23113:SF174 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 1 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 regulation of leukocyte mediated immunity#GO:0002703;cellular response to stimulus#GO:0051716;regulation of natural killer cell mediated immunity#GO:0002715;leukocyte activation#GO:0045321;positive regulation of natural killer cell mediated immunity#GO:0002717;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;cell activation#GO:0001775;regulation of defense response#GO:0031347;Ras protein signal transduction#GO:0007265;regulation of leukocyte mediated cytotoxicity#GO:0001910;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;regulation of natural killer cell mediated cytotoxicity#GO:0042269;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stress#GO:0080134;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;regulation of biological process#GO:0050789;T cell activation#GO:0042110;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cell killing#GO:0031341;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;intracellular signaling cassette#GO:0141124;lymphocyte activation#GO:0046649;regulation of response to external stimulus#GO:0032101;B cell activation#GO:0042113;positive regulation of response to external stimulus#GO:0032103 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>CalDAG-GEF#P00736 MONDO|Ensembl=ENSMODG00000018103.4|UniProtKB=A0A5F8H269 A0A5F8H269 ING4 PTHR10333:SF106 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 4 chromatin-protein adaptor activity#GO:0140463;histone H3 reader activity#GO:0140006;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000000233.4|UniProtKB=A0A5F8GY46 A0A5F8GY46 DNAH9 PTHR10676:SF257 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 9 catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;microtubule motor activity#GO:0003777 microtubule-based process#GO:0007017;cilium-dependent cell motility#GO:0060285;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294 axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;dynein complex#GO:0030286;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary plasm#GO:0097014;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000046753.1|UniProtKB=F7CQD1 F7CQD1 MRPL9 PTHR21368:SF27 50S RIBOSOMAL PROTEIN L9 LARGE RIBOSOMAL SUBUNIT PROTEIN BL9M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000003545.2|UniProtKB=F7GBL3 F7GBL3 DPEP1 PTHR10443:SF38 MICROSOMAL DIPEPTIDASE DIPEPTIDASE 1 peptidase activity#GO:0008233;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000012232.3|UniProtKB=F6Z6H6 F6Z6H6 PTHR24064:SF48 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 14 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000024575.1|UniProtKB=F7B6Y7 F7B6Y7 LOC100029533 PTHR19424:SF3 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR-BINDING PROTEIN 1 cellular response to stress#GO:0033554;response to heat#GO:0009408;heat acclimation#GO:0010286;cellular response to heat#GO:0034605;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to temperature stimulus#GO:0009266 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000009066.4|UniProtKB=A0A5F8GQ71 A0A5F8GQ71 ARHGAP35 PTHR46005:SF1 RHO GTPASE-ACTIVATING PROTEIN 190 RHO GTPASE-ACTIVATING PROTEIN 35 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 regulation of anatomical structure size#GO:0090066;regulation of cell projection organization#GO:0031344;regulation of axonogenesis#GO:0050770;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of cell size#GO:0008361;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 G-protein modulator#PC00022;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000011187.5|UniProtKB=F6ZYM7 F6ZYM7 GREB1 PTHR15720:SF13 GREB1-RELATED PROTEIN GREB1 anatomical structure morphogenesis#GO:0009653;tissue development#GO:0009888;epithelium development#GO:0060429;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;morphogenesis of an epithelium#GO:0002009;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729 MONDO|Ensembl=ENSMODG00000020606.4|UniProtKB=F6ZBG8 F6ZBG8 GABRA4 PTHR18945:SF393 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-4 ligand-gated monoatomic ion channel activity#GO:0015276;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023 cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;cellular process#GO:0009987;cellular component assembly#GO:0022607;monoatomic anion transmembrane transport#GO:0098656;nervous system development#GO:0007399;chloride transport#GO:0006821;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;synapse assembly#GO:0007416;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;developmental process#GO:0032502;transport#GO:0006810;establishment of localization#GO:0051234;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;chloride transmembrane transport#GO:1902476;localization#GO:0051179;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731 somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;cell junction#GO:0030054;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794;cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;dendritic tree#GO:0097447;dendrite#GO:0030425 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000002368.3|UniProtKB=F7GDA3 F7GDA3 PTHR11890:SF7 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR-LIKE 1 cytokine binding#GO:0019955;protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to cytokine#GO:0034097;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021439.4|UniProtKB=F7CB23 F7CB23 NAPG PTHR13768:SF2 SOLUBLE NSF ATTACHMENT PROTEIN SNAP GAMMA-SOLUBLE NSF ATTACHMENT PROTEIN membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000047401.1|UniProtKB=A0A5F8GG59 A0A5F8GG59 PTHR19446:SF479 REVERSE TRANSCRIPTASES RNA-DIRECTED DNA POLYMERASE reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000043055.1|UniProtKB=A0A5F8G1X8 A0A5F8G1X8 LOC100023193 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023982.2|UniProtKB=F7E8R8 F7E8R8 LOC100019272 PTHR26450:SF46 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51F1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040567.1|UniProtKB=A0A5F8HEJ7 A0A5F8HEJ7 FICD PTHR13504:SF34 FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145 PROTEIN ADENYLYLTRANSFERASE FICD phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;metabolic process#GO:0008152;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000013606.4|UniProtKB=F6VVH6 F6VVH6 WEE2 PTHR11042:SF75 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED WEE1-LIKE PROTEIN KINASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564;regulation of nuclear division#GO:0051783;regulation of cellular component organization#GO:0051128;regulation of reproductive process#GO:2000241;regulation of cellular process#GO:0050794;regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000020809.4|UniProtKB=F6S7A7 F6S7A7 ANXA3 PTHR10502:SF25 ANNEXIN ANNEXIN A3 binding#GO:0005488;small molecule binding#GO:0036094;phospholipid binding#GO:0005543;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000015758.4|UniProtKB=F7AGZ5 F7AGZ5 KCNAB1 PTHR43150:SF7 HYPERKINETIC, ISOFORM M VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-1 alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;binding#GO:0005488;transmembrane transporter binding#GO:0044325;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;protein binding#GO:0005515;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;biological regulation#GO:0065007;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of cellular process#GO:0050794;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of localization#GO:0032879;regulation of transport#GO:0051049 protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;neuron projection#GO:0043005;main axon#GO:0044304;cell periphery#GO:0071944;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;axon#GO:0030424 MONDO|Ensembl=ENSMODG00000002901.6|UniProtKB=A0A5F8GHA5 A0A5F8GHA5 CADPS PTHR12166:SF6 CALCIUM-DEPENDENT SECRETION ACTIVATOR CALCIUM-DEPENDENT SECRETION ACTIVATOR 1 localization#GO:0051179;regulation of secretion#GO:0051046;secretion#GO:0046903;secretion by cell#GO:0032940;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;positive regulation of secretion#GO:0051047;regulation of cellular process#GO:0050794;export from cell#GO:0140352;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;establishment of localization#GO:0051234;regulation of localization#GO:0032879;exocytosis#GO:0006887;regulation of transport#GO:0051049;transport#GO:0006810;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;cellular process#GO:0009987 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000009844.4|UniProtKB=F6WAN0 F6WAN0 TRDMT1 PTHR46098:SF1 TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000001789.4|UniProtKB=F6WIR4 F6WIR4 UTP15 PTHR19924:SF26 UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 HOMOLOG regulation of transcription by RNA polymerase I#GO:0006356;regulation of RNA metabolic process#GO:0051252;rRNA processing#GO:0006364;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of transcription by RNA polymerase I#GO:0045943;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;ribonucleoprotein complex biogenesis#GO:0022613;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000009547.3|UniProtKB=F7BK18 F7BK18 PTHR47063:SF1 RIBONUCLEASE H2 SUBUNIT C RIBONUCLEASE H2 SUBUNIT C nucleobase-containing compound catabolic process#GO:0034655;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;RNA catabolic process#GO:0006401;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 RNA metabolism protein#PC00031;endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000012664.2|UniProtKB=F6VXR3 F6VXR3 SEC61B PTHR13509:SF26 SEC61 SUBUNIT BETA PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT BETA nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of protein localization to endoplasmic reticulum#GO:0072599;localization within membrane#GO:0051668;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein transport#GO:0015031;post-translational protein targeting to membrane, translocation#GO:0031204;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620 membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;rough endoplasmic reticulum#GO:0005791;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum membrane#GO:0030867;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000002101.4|UniProtKB=F6UH76 F6UH76 CYP19A1 PTHR24291:SF43 CYTOCHROME P450 FAMILY 4 AROMATASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 reproductive structure development#GO:0048608;reproductive process#GO:0022414;response to stimulus#GO:0050896;developmental process involved in reproduction#GO:0003006;female gonad development#GO:0008585;system development#GO:0048731;reproductive system development#GO:0061458;anatomical structure development#GO:0048856;response to oxygen-containing compound#GO:1901700;animal gross anatomical part developmental process#GO:0160108;response to estradiol#GO:0032355;gonad development#GO:0008406;response to chemical#GO:0042221;response to lipid#GO:0033993;multicellular organismal process#GO:0032501;sex differentiation#GO:0007548;multicellular organism development#GO:0007275;animal organ development#GO:0048513;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 Androgen/estrogene/progesterone biosynthesis#P02727>Aromatase#P02828 MONDO|Ensembl=ENSMODG00000013547.3|UniProtKB=F7C3J4 F7C3J4 DOK4 PTHR21258:SF44 DOCKING PROTEIN RELATED DOCKING PROTEIN 4 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000001767.4|UniProtKB=F6WZ15 F6WZ15 ERGIC3 PTHR10984:SF85 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3 Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vesicle#GO:0031982;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000024628.2|UniProtKB=F6XVE3 F6XVE3 PTHR24215:SF3 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 2 structural molecule activity#GO:0005198;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 tissue development#GO:0009888;developmental process#GO:0032502;cellular developmental process#GO:0048869;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular anatomical entity morphogenesis#GO:0032989;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;Z disc#GO:0030018;nucleus#GO:0005634;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;sarcomere#GO:0030017;I band#GO:0031674 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000017204.4|UniProtKB=A0A5F8GJL8 A0A5F8GJL8 ATP8B2 PTHR24092:SF46 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE ID intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657 transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;membrane organization#GO:0061024;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;lipid transport#GO:0006869;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;Golgi organization#GO:0007030;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748 plasma membrane#GO:0005886;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000004001.3|UniProtKB=F7DRW4 F7DRW4 TUSC1 PTHR34768:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 89 TUMOR SUPPRESSOR CANDIDATE GENE 1 PROTEIN MONDO|Ensembl=ENSMODG00000022846.2|UniProtKB=A0A5F8GWX4 A0A5F8GWX4 NHSL2 PTHR23039:SF2 NANCE-HORAN SYNDROME PROTEIN NHS-LIKE PROTEIN 2 MONDO|Ensembl=ENSMODG00000036998.1|UniProtKB=K7E093 K7E093 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000013847.3|UniProtKB=F6X662 F6X662 LEAP2 PTHR21007:SF1 LIVER EXPRESSED ANTIMICROBIAL PEPTIDE 2 LIVER-EXPRESSED ANTIMICROBIAL PEPTIDE 2 MONDO|Ensembl=ENSMODG00000017237.4|UniProtKB=A0A5F8HL48 A0A5F8HL48 C1orf43 PTHR21425:SF2 NICE-3 LIPID TRANSPORT AUXILIARY PROTEIN 1 endocytosis#GO:0006897;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;phagocytosis#GO:0006909 MONDO|Ensembl=ENSMODG00000002722.4|UniProtKB=F6Z7H9 F6Z7H9 PTPRG PTHR19134:SF468 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE GAMMA hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;system development#GO:0048731;neuron development#GO:0048666;cell communication#GO:0007154;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000007748.4|UniProtKB=F7BJV1 F7BJV1 PIGO PTHR23071:SF1 PHOSPHATIDYLINOSITOL GLYCAN GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3, CATALYTIC SUBUNIT transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772 carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247;phospholipid metabolic process#GO:0006644;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000001528.5|UniProtKB=A0A5F8GXD2 A0A5F8GXD2 AHR PTHR10649:SF9 ARYL HYDROCARBON RECEPTOR ARYL HYDROCARBON RECEPTOR DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000019835.4|UniProtKB=F6YHY4 F6YHY4 PRR5L PTHR32428:SF3 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT BIT61-RELATED PROLINE-RICH PROTEIN 5-LIKE protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;TOR signaling#GO:0031929;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signal transduction#GO:0009967;TORC2 signaling#GO:0038203;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;TOR complex#GO:0038201 MONDO|Ensembl=ENSMODG00000000054.4|UniProtKB=F7BGL5 F7BGL5 MGAM PTHR22762:SF63 ALPHA-GLUCOSIDASE MALTASE-GLUCOAMYLASE glucosidase activity#GO:0015926;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;alpha-glucosidase activity#GO:0090599 glucosidase#PC00108 MONDO|Ensembl=ENSMODG00000015969.4|UniProtKB=F7FDA3 F7FDA3 PTHR43668:SF2 ALLANTOINASE ALLANTOINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824 nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;purine nucleobase catabolic process#GO:0006145;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152 hydrolase#PC00121 Allantoin degradation#P02725>Allantoinase#P02822;De novo pyrimidine ribonucleotides biosythesis#P02740>Dihydroorotase#P02928 MONDO|Ensembl=ENSMODG00000010162.4|UniProtKB=F6TAK6 F6TAK6 CDC45 PTHR10507:SF0 CDC45-RELATED PROTEIN CELL DIVISION CONTROL PROTEIN 45 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA replication origin binding#GO:0003688;single-stranded DNA binding#GO:0003697;chromatin binding#GO:0003682 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nuclear DNA replication#GO:0033260;mitotic DNA replication#GO:1902969;DNA replication initiation#GO:0006270;DNA recombination#GO:0006310;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;double-strand break repair#GO:0006302;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;cellular process#GO:0009987;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;cell cycle DNA replication#GO:0044786;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;double-strand break repair via break-induced replication#GO:0000727;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;mitotic cell cycle#GO:0000278 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;DNA replication preinitiation complex#GO:0031261;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991 replication origin binding protein#PC00199;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000050485.1|UniProtKB=F7E760 F7E760 PTHR13058:SF24 THREE PRIME REPAIR EXONUCLEASE 1, 2 THREE PRIME REPAIR EXONUCLEASE 2 hydrolase activity#GO:0016787;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;exonuclease activity#GO:0004527;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity#GO:0004529;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536 macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;DNA catabolic process#GO:0006308;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000017654.5|UniProtKB=F6YK01 F6YK01 SERPIND1 PTHR11461:SF30 SERINE PROTEASE INHIBITOR, SERPIN HEPARIN COFACTOR 2 enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>HCII#P00456 MONDO|Ensembl=ENSMODG00000005258.4|UniProtKB=F7GGW4 F7GGW4 KDSR PTHR43550:SF3 3-KETODIHYDROSPHINGOSINE REDUCTASE 3-KETODIHYDROSPHINGOSINE REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 lipid metabolic process#GO:0006629;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 reductase#PC00198;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000004756.4|UniProtKB=F6X1D2 F6X1D2 SPPL2B PTHR12174:SF39 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 2B peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;Golgi-associated vesicle membrane#GO:0030660;intracellular organelle#GO:0043229;side of membrane#GO:0098552;organelle subcompartment#GO:0031984;lysosomal membrane#GO:0005765;cytoplasmic vesicle membrane#GO:0030659;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;cytoplasm#GO:0005737;vacuole#GO:0005773;cytoplasmic side of membrane#GO:0098562;endoplasmic reticulum#GO:0005783;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;endoplasmic reticulum membrane#GO:0005789;Golgi-associated vesicle#GO:0005798;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090 aspartic protease#PC00053;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000007684.4|UniProtKB=F7FN62 F7FN62 UNK PTHR14493:SF36 UNKEMPT FAMILY MEMBER RING FINGER PROTEIN UNKEMPT HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;multicellular organismal process#GO:0032501 MONDO|Ensembl=ENSMODG00000039665.1|UniProtKB=A0A5F8GW20 A0A5F8GW20 KLF13 PTHR23235:SF21 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 13 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000037132.1|UniProtKB=A0A5F8H4R4 A0A5F8H4R4 ING1 PTHR10333:SF85 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 1 chromatin-protein adaptor activity#GO:0140463;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;histone reader activity#GO:0140566 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000015401.4|UniProtKB=F6T501 F6T501 BCS1L PTHR23070:SF255 BCS1 AAA-TYPE ATPASE MITOCHONDRIAL CHAPERONE BCS1 protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein localization to mitochondrion#GO:0070585;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;establishment of protein localization#GO:0045184;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000019165.4|UniProtKB=F7F934 F7F934 JAK3 PTHR45807:SF3 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE JAK3 catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;hormone receptor binding#GO:0051427;non-membrane spanning protein tyrosine kinase activity#GO:0004715 interleukin-2-mediated signaling pathway#GO:0038110;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cellular response to peptide hormone stimulus#GO:0071375;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;immune response#GO:0006955;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;response to other organism#GO:0051707;developmental process#GO:0032502;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;innate immune response#GO:0045087;cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to oxygen-containing compound#GO:1901700;response to peptide#GO:1901652;response to biotic stimulus#GO:0009607;response to hormone#GO:0009725;response to stress#GO:0006950;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;defense response to symbiont#GO:0140546;response to type II interferon#GO:0034341;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;interleukin-15-mediated signaling pathway#GO:0035723;interleukin-9-mediated signaling pathway#GO:0038113;cell surface receptor signaling pathway via STAT#GO:0097696;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;interleukin-7-mediated signaling pathway#GO:0038111 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 Interleukin signaling pathway#P00036>Jak#P00978;JAK/STAT signaling pathway#P00038>Jak#P01034;PDGF signaling pathway#P00047>Jak#P01155 MONDO|Ensembl=ENSMODG00000012396.4|UniProtKB=F6PN31 F6PN31 NUP214 PTHR23193:SF21 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE COMPLEX PROTEIN NUP214 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236;localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;nuclear export#GO:0051168;protein import into nucleus#GO:0006606;nucleocytoplasmic transport#GO:0006913;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000008959.4|UniProtKB=F7G2F3 F7G2F3 GLRA1 PTHR18945:SF213 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-1 chloride channel activity#GO:0005254;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;localization#GO:0051179;chloride transmembrane transport#GO:1902476;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 cell junction#GO:0030054;synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;plasma membrane#GO:0005886;organelle#GO:0043226;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell periphery#GO:0071944;membrane#GO:0016020;postsynapse#GO:0098794 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000003425.3|UniProtKB=A0A5F8HF44 A0A5F8HF44 PTHR15191:SF14 PROTEIN CBG20567 PITUITARY TUMOR-TRANSFORMING GENE 1 PROTEIN-INTERACTING PROTEIN protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000050070.1|UniProtKB=A0A5F8GQT1 A0A5F8GQT1 PTHR26453:SF20 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6B9 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015086.4|UniProtKB=F7F3H6 F7F3H6 HYCC2 PTHR31220:SF3 HYCCIN RELATED HYCCIN 2 biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule localization#GO:0033036;organophosphate metabolic process#GO:0019637;intracellular protein localization#GO:0008104;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;protein localization to cell periphery#GO:1990778;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;localization#GO:0051179;cellular localization#GO:0051641;organophosphate biosynthetic process#GO:0090407;localization within membrane#GO:0051668;phosphatidylinositol phosphate biosynthetic process#GO:0046854 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000021101.4|UniProtKB=F6UI11 F6UI11 ATP6AP2 PTHR13351:SF1 RENIN RECEPTOR RENIN RECEPTOR regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signal transduction#GO:0009967;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020613.4|UniProtKB=F6ZB58 F6ZB58 AIMP1 PTHR11586:SF51 TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cell motility#GO:0048870;protein biosynthetic process#GO:0160307;signaling#GO:0023052;immune system process#GO:0002376;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;cell communication#GO:0007154;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;cell migration#GO:0016477;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;cell-cell signaling#GO:0007267;biosynthetic process#GO:0009058;tRNA metabolic process#GO:0006399;leukocyte migration#GO:0050900;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170 catalytic complex#GO:1902494;extracellular region#GO:0005576;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translational protein#PC00263 MONDO|Ensembl=ENSMODG00000001175.4|UniProtKB=F6UU98 F6UU98 TMEM131L PTHR22050:SF2 RW1 PROTEIN HOMOLOG TRANSMEMBRANE PROTEIN 131-LIKE negative regulation of signal transduction#GO:0009968;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000002399.4|UniProtKB=F7EHL7 F7EHL7 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000023771.1|UniProtKB=F6SDJ3 F6SDJ3 PTHR11726:SF10 60S RIBOSOMAL PROTEIN L10 LARGE RIBOSOMAL SUBUNIT PROTEIN UL16 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000013865.4|UniProtKB=A0A5F8GK08 A0A5F8GK08 CADM1 PTHR45889:SF2 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;homophilic cell-cell adhesion#GO:0007156;detection of stimulus#GO:0051606;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;regulation of natural killer cell mediated cytotoxicity#GO:0042269;positive regulation of response to stimulus#GO:0048584;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stress#GO:0080134;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;regulation of leukocyte mediated immunity#GO:0002703;regulation of natural killer cell mediated immunity#GO:0002715;regulation of response to biotic stimulus#GO:0002831;positive regulation of natural killer cell mediated immunity#GO:0002717;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;cell recognition#GO:0008037;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;positive regulation of immune system process#GO:0002684;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell adhesion#GO:0007155;regulation of cell killing#GO:0031341;regulation of lymphocyte mediated immunity#GO:0002706 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000016268.5|UniProtKB=A0A5F8HKN3 A0A5F8HKN3 NBEAL1 PTHR13743:SF115 BEIGE/BEACH-RELATED NEUROBEACHIN-LIKE PROTEIN 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000373.2|UniProtKB=F6R948 F6R948 PTHR11910:SF1 ATP SYNTHASE DELTA CHAIN ATP SYNTHASE PERIPHERAL STALK SUBUNIT OSCP, MITOCHONDRIAL catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;proton motive force-driven ATP synthesis#GO:0015986;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 primary active transporter#PC00068;transporter#PC00227;ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000040935.1|UniProtKB=A0A5F8HJL6 A0A5F8HJL6 HSPB3 PTHR47097:SF1 HEAT SHOCK PROTEIN BETA-3 HEAT SHOCK PROTEIN BETA-3 supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000048189.1|UniProtKB=A0A5F8GAQ9 A0A5F8GAQ9 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000013523.4|UniProtKB=A0A5F8GEQ8 A0A5F8GEQ8 KLC1 PTHR45783:SF7 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 1 cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 MONDO|Ensembl=ENSMODG00000042252.1|UniProtKB=A0A5F8GKQ1 A0A5F8GKQ1 OR10J4 PTHR26451:SF107 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10J4 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000065.4|UniProtKB=F6QTN5 F6QTN5 DPY19L1 PTHR31488:SF5 DPY-19-LIKE 1, LIKE (H. SAPIENS) PROTEIN C-MANNOSYL-TRANSFERASE DPY19L1 glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000050776.1|UniProtKB=F7AWV3 F7AWV3 LOC100028935 PTHR48002:SF116 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023193.1|UniProtKB=F7F8X9 F7F8X9 CDK5R1 PTHR23401:SF2 CYCLIN DEPENDANT KINASE-5 ACTIVATOR CYCLIN-DEPENDENT KINASE 5 ACTIVATOR 1 molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme activator activity#GO:0008047;kinase activator activity#GO:0019209;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;protein kinase activator activity#GO:0030295 anatomical structure development#GO:0048856;system development#GO:0048731;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;axon guidance#GO:0007411;axon development#GO:0061564;multicellular organismal process#GO:0032501;brain development#GO:0007420;plasma membrane bounded cell projection organization#GO:0120036;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;central nervous system development#GO:0007417;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;head development#GO:0060322;nervous system development#GO:0007399 site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;growth cone#GO:0030426;axon#GO:0030424;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005 kinase modulator#PC00140;kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000013493.4|UniProtKB=F7F8S0 F7F8S0 TCERG1L PTHR15377:SF5 TRANSCRIPTION ELONGATION REGULATOR 1 TRANSCRIPTION ELONGATION REGULATOR 1-LIKE PROTEIN transcription coregulator activity#GO:0003712;binding#GO:0005488;RNA polymerase binding#GO:0070063;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;protein binding#GO:0005515 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000010595.3|UniProtKB=F7G8G7 F7G8G7 C2orf78 PTHR31466:SF1 GENE 5591-RELATED RIKEN CDNA 4930433I11 GENE MONDO|Ensembl=ENSMODG00000004598.3|UniProtKB=F6QIK5 F6QIK5 ACTL6B PTHR11937:SF196 ACTIN ACTIN-LIKE PROTEIN 6B chromatin binding#GO:0003682;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;structural molecule activity#GO:0005198 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889 chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;ATPase complex#GO:1904949;protein acetyltransferase complex#GO:0031248;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;chromatin#GO:0000785;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535 actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000015703.4|UniProtKB=F7DGG8 F7DGG8 CCNL1 PTHR10026:SF64 CYCLIN CYCLIN-L1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 kinase modulator#PC00140;kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000011500.4|UniProtKB=F6V1M4 F6V1M4 LDB1 PTHR10378:SF7 LIM DOMAIN-BINDING PROTEIN LIM DOMAIN-BINDING PROTEIN 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 Gonadotropin-releasing hormone receptor pathway#P06664>CLIM2#P06736 MONDO|Ensembl=ENSMODG00000012519.4|UniProtKB=F6Q001 F6Q001 DDX55 PTHR24031:SF2 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX55 ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000019201.4|UniProtKB=F6ZIW9 F6ZIW9 CDKL2 PTHR24056:SF241 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000024788.1|UniProtKB=F7G0G0 F7G0G0 PTHR11143:SF11 60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL24 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000016453.4|UniProtKB=F7A409 F7A409 MEFV PTHR24103:SF606 E3 UBIQUITIN-PROTEIN LIGASE TRIM PYRIN aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 immune system process#GO:0002376;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;response to external stimulus#GO:0009605;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000006503.4|UniProtKB=F7EK23 F7EK23 PTHR22747:SF28 NUCLEOPLASMIN NUCLEOPHOSMIN histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;protein binding#GO:0005515 transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;regulation of gene expression#GO:0010468;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;ribosome localization#GO:0033750;regulation of microtubule-based process#GO:0032886;organelle localization#GO:0051640;regulation of RNA metabolic process#GO:0051252;nuclear export#GO:0051168;nuclear transport#GO:0051169;regulation of DNA-templated transcription#GO:0006355;localization#GO:0051179;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;ribosomal small subunit biogenesis#GO:0042274;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;regulation of cell cycle process#GO:0010564;positive regulation of macromolecule metabolic process#GO:0010604;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular localization#GO:0051641;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;ribosomal large subunit export from nucleus#GO:0000055;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;chromatin remodeling#GO:0006338;regulation of cell cycle#GO:0051726;establishment of organelle localization#GO:0051656;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular component organization#GO:0051128 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000017573.3|UniProtKB=A0A5F8GTB6 A0A5F8GTB6 PEF1 PTHR46212:SF10 PEFLIN PEFLIN Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;vesicle budding from membrane#GO:0006900;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membrane organization#GO:0061024;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043 MONDO|Ensembl=ENSMODG00000001478.3|UniProtKB=Q2AB86 Q2AB86 TAS2R41 PTHR11394:SF73 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 41 signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;transmembrane signaling receptor activity#GO:0004888 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005894.4|UniProtKB=F6SLN8 F6SLN8 C16orf89 PTHR33539:SF1 UPF0764 PROTEIN C16ORF89 UPF0764 PROTEIN C16ORF89 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000008992.4|UniProtKB=F7BQD1 F7BQD1 GRAP2 PTHR46037:SF3 PROTEIN ENHANCER OF SEVENLESS 2B GRB2-RELATED ADAPTER PROTEIN 2 growth factor receptor binding#GO:0070851;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;cell communication#GO:0007154 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;COP9 signalosome#GO:0008180;nucleus#GO:0005634;cell periphery#GO:0071944;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Grb#P00848;PDGF signaling pathway#P00047>Grb2#P01148;T cell activation#P00053>Gads#P01327 MONDO|Ensembl=ENSMODG00000004554.4|UniProtKB=F6R5G9 F6R5G9 CEP128 PTHR46657:SF1 CENTROSOMAL PROTEIN OF 128 KDA CENTROSOMAL PROTEIN 128 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814 MONDO|Ensembl=ENSMODG00000014651.4|UniProtKB=A0A5F8HA59 A0A5F8HA59 PTHR10388:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 EUKARYOTIC TRANSLATION INITIATION FACTOR 1 binding#GO:0005488;nucleic acid binding#GO:0003676;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 ribonucleoprotein complex#GO:1990904;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000024939.1|UniProtKB=F6VDM5 F6VDM5 MAB21L2 PTHR10656:SF37 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MAB-21-LIKE 2 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 nucleotidyltransferase#PC00174;transferase#PC00220 MONDO|Ensembl=ENSMODG00000009909.4|UniProtKB=F6RU49 F6RU49 BLMH PTHR10363:SF2 BLEOMYCIN HYDROLASE BLEOMYCIN HYDROLASE peptidase activity#GO:0008233;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;aminopeptidase activity#GO:0004177;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 sulfur compound catabolic process#GO:0044273;metabolic process#GO:0008152;response to chemical#GO:0042221;amino acid metabolic process#GO:0006520;sulfur compound metabolic process#GO:0006790;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to toxic substance#GO:0009636;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000050047.1|UniProtKB=A0A5F8G6X7 A0A5F8G6X7 PTHR48001:SF115 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1S1-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028815.2|UniProtKB=K7E4W9 K7E4W9 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000016826.4|UniProtKB=A0A5F8GMB0 A0A5F8GMB0 CDC123 PTHR15323:SF6 D123 PROTEIN TRANSLATION INITIATION FACTOR EIF2 ASSEMBLY PROTEIN cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000050560.1|UniProtKB=A0A5F8GG84 A0A5F8GG84 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000043217.1|UniProtKB=A0A5F8GLG8 A0A5F8GLG8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000020405.4|UniProtKB=F7BZE2 F7BZE2 TARS1 PTHR11451:SF36 THREONINE-TRNA LIGASE THREONINE--TRNA LIGASE 1, CYTOPLASMIC catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000051546.1|UniProtKB=A0A5F8G280 A0A5F8G280 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016396.5|UniProtKB=F7E905 F7E905 CREBBP PTHR13808:SF34 CBP/P300-RELATED CREB-BINDING PROTEIN acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;nucleic acid binding#GO:0003676;N-acetyltransferase activity#GO:0008080;chromatin binding#GO:0003682;DNA binding#GO:0003677;histone acetyltransferase activity#GO:0004402;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;chromatin DNA binding#GO:0031490;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;binding#GO:0005488;acetyltransferase activity#GO:0016407;transcription regulator activity#GO:0140110;protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;transferase activity#GO:0016740;transcription coactivator activity#GO:0003713;protein N-acetyltransferase activity#GO:0034212 regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785 histone modifying enzyme#PC00261 Wnt signaling pathway#P00057>CBP#P01448;Huntington disease#P00029>CBP#P00777;p53 pathway#P00059>CBP#P04623;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Transcription regulation by bZIP transcription factor#P00055>CBP/P300#P01387;Gonadotropin-releasing hormone receptor pathway#P06664>CBP#P06755;Hypoxia response via HIF activation#P00030>P300#P00814;Hedgehog signaling pathway#P00025>CBP#P00691 MONDO|Ensembl=ENSMODG00000016146.4|UniProtKB=F7D7C9 F7D7C9 TCEA3 PTHR11477:SF4 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 3 transcription regulator activity#GO:0140110;transcription elongation factor activity#GO:0003711 DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000040037.1|UniProtKB=A0A5F8G951 A0A5F8G951 LOC100618822 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000013284.4|UniProtKB=F7AA89 F7AA89 PDE1C PTHR11347:SF32 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE DUAL SPECIFICITY CALCIUM_CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1C catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell body#GO:0044297 hydrolase#PC00121;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000050612.1|UniProtKB=A0A5F8GQE7 A0A5F8GQE7 PTHR13305:SF0 RIBOSOME BIOGENESIS PROTEIN NOP10 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000015658.2|UniProtKB=F7EII3 F7EII3 PTHR12735:SF27 BOLA-LIKE PROTEIN-RELATED BOLA-LIKE PROTEIN 2 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000045593.1|UniProtKB=A0A5F8H8Y5 A0A5F8H8Y5 SLC25A42 PTHR24089:SF736 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL COENZYME A TRANSPORTER SLC25A42 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 MONDO|Ensembl=ENSMODG00000003233.4|UniProtKB=F6TY80 F6TY80 FBXO42 PTHR46432:SF1 F-BOX ONLY PROTEIN 42 F-BOX ONLY PROTEIN 42 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000021026.4|UniProtKB=A0A5F8GKA7 A0A5F8GKA7 PKNOX1 PTHR11850:SF80 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN PKNOX1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;angiogenesis#GO:0001525;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;tube development#GO:0035295;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>Prep1#P06829 MONDO|Ensembl=ENSMODG00000038269.1|UniProtKB=A0A5F8GLG1 A0A5F8GLG1 MRPL10 PTHR11560:SF15 39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL10M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000007301.5|UniProtKB=F7FBU2 F7FBU2 PANK1 PTHR12280:SF23 PANTOTHENATE KINASE PANTOTHENATE KINASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 MONDO|Ensembl=ENSMODG00000020383.4|UniProtKB=A0A5F8GBW1 A0A5F8GBW1 RAB3IP PTHR14430:SF2 RABIN3-RELATED RAB-3A-INTERACTING PROTEIN molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000016992.4|UniProtKB=F6U5C4 F6U5C4 NSUN3 PTHR22808:SF8 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING TRNA (CYTOSINE(34)-C(5))-METHYLTRANSFERASE, MITOCHONDRIAL transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000003124.3|UniProtKB=A0A5F8G401 A0A5F8G401 COQ5 PTHR43591:SF116 METHYLTRANSFERASE 2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;ketone metabolic process#GO:0042180;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ubiquinone biosynthetic process#GO:0006744;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058 transferase#PC00220;methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000015607.2|UniProtKB=F6Z5I2 F6Z5I2 VAMP8 PTHR45701:SF7 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 8 binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;syntaxin binding#GO:0019905 vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;biological regulation#GO:0065007;cellular component biogenesis#GO:0044085;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;transport#GO:0006810;regulation of body fluid levels#GO:0050878;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;secretion#GO:0046903;localization#GO:0051179;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;organelle#GO:0043226;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532 MONDO|Ensembl=ENSMODG00000007741.3|UniProtKB=F7C457 F7C457 PTHR48001:SF15 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021081.3|UniProtKB=F6V138 F6V138 PWP2 PTHR19858:SF0 WD40 REPEAT PROTEIN PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;90S preribosome#GO:0030686;small-subunit processome#GO:0032040;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000008010.4|UniProtKB=F6PG43 F6PG43 CNGB3 PTHR45638:SF8 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL BETA-3 ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;monoatomic ion transmembrane transporter activity#GO:0015075;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;gated channel activity#GO:0022836;guanyl nucleotide binding#GO:0019001;monoatomic cation transmembrane transporter activity#GO:0008324;guanyl ribonucleotide binding#GO:0032561 monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;transporter complex#GO:1990351;cation channel complex#GO:0034703;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;membrane protein complex#GO:0098796;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;cilium#GO:0005929 ion channel#PC00133;ligand-gated ion channel#PC00141 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 MONDO|Ensembl=ENSMODG00000006611.4|UniProtKB=F7GEX1 F7GEX1 NUP188 PTHR31431:SF1 NUCLEOPORIN NUP188 HOMOLOG NUCLEOPORIN NUP188 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;nucleus#GO:0005634;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 transporter#PC00227 MONDO|Ensembl=ENSMODG00000046801.1|UniProtKB=K7E4U8 K7E4U8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000027792.2|UniProtKB=A0A5F8GM12 A0A5F8GM12 PTHR24377:SF1028 IP01015P-RELATED ZINC FINGER PROTEIN 84 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010348.4|UniProtKB=F6S8C3 F6S8C3 CLPX PTHR48102:SF7 ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED ATP-DEPENDENT CLPX-LIKE CHAPERONE, MITOCHONDRIAL catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ATP-dependent activity#GO:0140657;ATP binding#GO:0005524;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190 MONDO|Ensembl=ENSMODG00000042761.1|UniProtKB=A0A5F8GNY0 A0A5F8GNY0 PTHR24056:SF126 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 12 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784 protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000019513.3|UniProtKB=F6VD85 F6VD85 SEMA4B PTHR11036:SF14 SEMAPHORIN SEMAPHORIN-4B receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;axon development#GO:0061564;axon guidance#GO:0007411;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;chemotaxis#GO:0006935;regulation of cellular process#GO:0050794;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;taxis#GO:0042330;response to chemical#GO:0042221;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000003988.4|UniProtKB=F7DSP2 F7DSP2 F10 PTHR24278:SF28 COAGULATION FACTOR COAGULATION FACTOR X catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 Blood coagulation#P00011>FXa#P00445;Blood coagulation#P00011>FX#P00430 MONDO|Ensembl=ENSMODG00000016096.4|UniProtKB=F7CA52 F7CA52 SEC62 PTHR12443:SF9 TRANSLOCATION PROTEIN SEC62 TRANSLOCATION PROTEIN SEC62 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transmembrane protein transporter activity#GO:0008320 post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting#GO:0006605;localization within membrane#GO:0051668;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;post-translational protein targeting to membrane, translocation#GO:0031204;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting to membrane#GO:0006612;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein targeting to ER#GO:0045047 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 MONDO|Ensembl=ENSMODG00000020561.4|UniProtKB=F7APN8 F7APN8 PTHR21245:SF6 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 47 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000048716.1|UniProtKB=K7E5S8 K7E5S8 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000025540.2|UniProtKB=F6V1B4 F6V1B4 PTHR26452:SF828 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000316.4|UniProtKB=A0A5F8G4W0 A0A5F8G4W0 BAHD1 PTHR46576:SF1 BROMO ADJACENT HOMOLOGY DOMAIN-CONTAINING 1 PROTEIN BROMO ADJACENT HOMOLOGY DOMAIN-CONTAINING 1 PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000012839.4|UniProtKB=F7CTK8 F7CTK8 PRICKLE4 PTHR24214:SF34 PDZ AND LIM DOMAIN PROTEIN ZASP PRICKLE-LIKE PROTEIN 4 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cellular component organization#GO:0016043;circulatory system development#GO:0072359;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;heart development#GO:0007507;multicellular organismal process#GO:0032501 organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;myofibril#GO:0030016;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cell-cell junction#GO:0005911;contractile muscle fiber#GO:0043292;actomyosin#GO:0042641;Z disc#GO:0030018;sarcomere#GO:0030017;cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;adherens junction#GO:0005912;cytoskeleton#GO:0005856;stress fiber#GO:0001725;I band#GO:0031674;actin filament#GO:0005884 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000003855.2|UniProtKB=F7DU27 F7DU27 ACSF3 PTHR24096:SF435 LONG-CHAIN-FATTY-ACID--COA LIGASE MALONATE--COA LIGASE ACSF3, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 ligase#PC00142 MONDO|Ensembl=ENSMODG00000014210.3|UniProtKB=F6TQC9 F6TQC9 RPS18 PTHR10871:SF3 30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18 SMALL RIBOSOMAL SUBUNIT PROTEIN US13 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000045620.1|UniProtKB=A0A5F8G829 A0A5F8G829 AP3M2 PTHR10529:SF341 AP COMPLEX SUBUNIT MU AP-3 COMPLEX SUBUNIT MU-2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034 Golgi apparatus#GO:0005794;AP-type membrane coat adaptor complex#GO:0030119;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000040283.1|UniProtKB=F6TBS2 F6TBS2 LOC100017292 PTHR26453:SF302 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003833.3|UniProtKB=F7GJC6 F7GJC6 LOC130458488 PTHR23120:SF39 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO_MAESTRO-LIKE HEAT-REPEATS DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000049818.1|UniProtKB=K7E034 K7E034 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000049815.1|UniProtKB=A0A5F8G5U3 A0A5F8G5U3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000042888.1|UniProtKB=A0A5F8G347 A0A5F8G347 G6PC1 PTHR12591:SF3 GLUCOSE-6-PHOSPHATASE GLUCOSE-6-PHOSPHATASE CATALYTIC SUBUNIT 1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;sugar-phosphatase activity#GO:0050308;hydrolase activity, acting on ester bonds#GO:0016788 small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;carbohydrate biosynthetic process#GO:0016051;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;hexose biosynthetic process#GO:0019319;gluconeogenesis#GO:0006094;cellular process#GO:0009987;glucose metabolic process#GO:0006006;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;small molecule biosynthetic process#GO:0044283 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 hydrolase#PC00121;phosphatase#PC00181 Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103 MONDO|Ensembl=ENSMODG00000004198.4|UniProtKB=F6Y8Y4 F6Y8Y4 CNTN6 PTHR12231:SF237 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN CONTACTIN-6 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000049570.1|UniProtKB=A0A5F8GII3 A0A5F8GII3 PTHR10971:SF36 MRNA EXPORT FACTOR AND BUB3 MITOTIC CHECKPOINT PROTEIN BUB3 ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 negative regulation of cell cycle#GO:0045786;negative regulation of chromosome segregation#GO:0051985;negative regulation of mitotic sister chromatid segregation#GO:0033048;regulation of chromosome segregation#GO:0051983;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of chromosome separation#GO:1905818;regulation of cell cycle process#GO:0010564;negative regulation of sister chromatid segregation#GO:0033046;cellular process#GO:0009987;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;regulation of mitotic sister chromatid separation#GO:0010965;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;regulation of mitotic nuclear division#GO:0007088;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;negative regulation of cell cycle process#GO:0010948;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;cell communication#GO:0007154;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;negative regulation of chromosome organization#GO:2001251;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841 chromosome#GO:0005694;organelle lumen#GO:0043233;kinetochore#GO:0000776;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;condensed chromosome, centromeric region#GO:0000779;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000041291.1|UniProtKB=A0A5F8HI63 A0A5F8HI63 LOC100023080 PTHR26452:SF930 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000008718.4|UniProtKB=F6PVB3 F6PVB3 SLC29A3 PTHR10332:SF17 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 3 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleoside transmembrane transporter activity#GO:0005337;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 transporter#PC00227 MONDO|Ensembl=ENSMODG00000041712.1|UniProtKB=A0A5F8GSZ0 A0A5F8GSZ0 PTHR11908:SF99 XANTHINE DEHYDROGENASE ALDEHYDE OXIDASE 3 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000009136.4|UniProtKB=A0A5F8GF64 A0A5F8GF64 STRN4 PTHR15653:SF1 STRIATIN STRIATIN-4 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of hippo signaling#GO:0035331;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794;cell body#GO:0044297;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447 MONDO|Ensembl=ENSMODG00000014209.3|UniProtKB=F6TQE0 F6TQE0 UBE2B PTHR24067:SF246 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 B ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein modification process#GO:0036211;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000015794.2|UniProtKB=F7FS37 F7FS37 MCCD1 PTHR37877:SF1 MITOCHONDRIAL COILED-COIL DOMAIN PROTEIN 1 MITOCHONDRIAL COILED-COIL DOMAIN PROTEIN 1 MONDO|Ensembl=ENSMODG00000042735.1|UniProtKB=A0A5F8G883 A0A5F8G883 LYRM4 PTHR13166:SF7 PROTEIN C6ORF149 LYR MOTIF-CONTAINING PROTEIN 4 iron-sulfur cluster assembly#GO:0016226;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;sulfurtransferase complex#GO:1990228;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000002074.4|UniProtKB=F6TWT5 F6TWT5 PSRC1 PTHR21584:SF1 DIFFERENTIAL DISPLAY AND ACTIVATED BY P53 DDA3 /G2 S PHASE EXPRESSED 1 PROLINE_SERINE-RICH COILED-COIL PROTEIN 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;chromosome localization#GO:0050000;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;localization#GO:0051179;organelle fission#GO:0048285;organelle localization#GO:0051640;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;mitotic metaphase chromosome alignment#GO:0007080;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813 organelle#GO:0043226;cellular anatomical structure#GO:0110165;spindle pole#GO:0000922;microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;spindle#GO:0005819;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000014235.2|UniProtKB=A0A5F8HJ81 A0A5F8HJ81 PTHR12595:SF0 POS9-ACTIVATING FACTOR FAP7-RELATED ADENYLATE KINASE ISOENZYME 6 catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotide binding#GO:0000166;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;kinase activity#GO:0016301;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;nucleobase-containing compound kinase activity#GO:0019205;ATP binding#GO:0005524;binding#GO:0005488;phosphotransferase activity, phosphate group as acceptor#GO:0016776 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000036674.1|UniProtKB=A0A5F8GEI2 A0A5F8GEI2 PTHR37000:SF3 MUCIN-22 MUCIN-22 MONDO|Ensembl=ENSMODG00000007706.3|UniProtKB=F7F9C6 F7F9C6 PTHR11785:SF213 AMINO ACID TRANSPORTER SOLUTE CARRIER FAMILY 7 MEMBER 7 transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 transport#GO:0006810;cellular process#GO:0009987;amino acid transport#GO:0006865;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000028041.2|UniProtKB=K7E5P7 K7E5P7 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000023738.2|UniProtKB=F6X7H0 F6X7H0 B3GALT4 PTHR11214:SF378 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 4 glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000036676.1|UniProtKB=F6SMH5 F6SMH5 LOC100027183 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010339.4|UniProtKB=F6S934 F6S934 PAK1IP1 PTHR44675:SF1 PAK1 INTERACTING PROTEIN 1 P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;kinase inhibitor activity#GO:0019210;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;protein kinase regulator activity#GO:0019887;enzyme inhibitor activity#GO:0004857 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 MONDO|Ensembl=ENSMODG00000045397.1|UniProtKB=A0A5F8HHF0 A0A5F8HHF0 MSRB2 PTHR10173:SF37 METHIONINE SULFOXIDE REDUCTASE METHIONINE-R-SULFOXIDE REDUCTASE B2, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;reductase#PC00198 MONDO|Ensembl=ENSMODG00000008152.4|UniProtKB=F7ELD2 F7ELD2 ATP2B3 PTHR24093:SF284 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 3 monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 homeostatic process#GO:0042592;regulation of cytosolic calcium ion concentration#GO:0051480;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074 membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000009629.1|UniProtKB=F6RDS5 F6RDS5 PEA15 PTHR48169:SF1 DED DOMAIN-CONTAINING PROTEIN ASTROCYTIC PHOSPHOPROTEIN PEA-15 regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of cell communication#GO:0010648;negative regulation of programmed cell death#GO:0043069;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 Gonadotropin-releasing hormone receptor pathway#P06664>PEA-15#P06853 MONDO|Ensembl=ENSMODG00000044111.1|UniProtKB=A0A5F8H6D7 A0A5F8H6D7 PTHR14947:SF28 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000047183.1|UniProtKB=A0A5F8GGW7 A0A5F8GGW7 CDNF PTHR12990:SF9 ARMET-LIKE PROTEIN CEREBRAL DOPAMINE NEUROTROPHIC FACTOR receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular component organization#GO:0016043;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000020259.4|UniProtKB=A0A5F8H9F7 A0A5F8H9F7 CKMT2 PTHR11547:SF19 ARGININE OR CREATINE KINASE CREATINE KINASE S-TYPE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;transferase activity#GO:0016740;catalytic activity#GO:0003824 organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;amino acid kinase#PC00045 MONDO|Ensembl=ENSMODG00000029376.2|UniProtKB=K7E514 K7E514 PTHR22035:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 7 COILED-COIL DOMAIN-CONTAINING PROTEIN 7 MONDO|Ensembl=ENSMODG00000015482.4|UniProtKB=F6WFG3 F6WFG3 SLC11A1 PTHR11706:SF52 SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 1 metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;iron ion transmembrane transporter activity#GO:0005381;transition metal ion transmembrane transporter activity#GO:0046915 establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;iron ion transmembrane transport#GO:0034755;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;iron ion transport#GO:0006826;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000008215.4|UniProtKB=A0A5F8GB15 A0A5F8GB15 LOC100015520 PTHR24300:SF180 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2A6 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;binding#GO:0005488;tetrapyrrole binding#GO:0046906 long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;response to chemical#GO:0042221;icosanoid metabolic process#GO:0006690;cellular response to xenobiotic stimulus#GO:0071466;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;secondary metabolic process#GO:0019748;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;xenobiotic metabolic process#GO:0006805;oxoacid metabolic process#GO:0043436;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;olefinic compound metabolic process#GO:0120254 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxygenase#PC00177 Nicotine degradation#P05914>CYP2A6#P05984 MONDO|Ensembl=ENSMODG00000020661.3|UniProtKB=F7E5W3 F7E5W3 CISD2 PTHR13680:SF33 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 2 transaminase activity#GO:0008483;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity#GO:0016740;iron-sulfur cluster binding#GO:0051536 cellular process#GO:0009987;autophagy#GO:0006914;monoatomic ion homeostasis#GO:0050801;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;catabolic process#GO:0009056;intracellular monoatomic ion homeostasis#GO:0006873;process utilizing autophagic mechanism#GO:0061919;inorganic ion homeostasis#GO:0098771 organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 MONDO|Ensembl=ENSMODG00000004452.3|UniProtKB=F6R7N8 F6R7N8 PRKAR1A PTHR11635:SF129 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE I-ALPHA REGULATORY SUBUNIT molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;kinase inhibitor activity#GO:0019210;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;protein kinase A binding#GO:0051018;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;nucleotide binding#GO:0000166;enzyme inhibitor activity#GO:0004857 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Endothelin signaling pathway#P00019>PKA#P00570;GABA-B receptor II signaling#P05731>PKA#P05752;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Hedgehog signaling pathway#P00025>PKA#P00682;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059 MONDO|Ensembl=ENSMODG00000042379.1|UniProtKB=A0A5F8GVM9 A0A5F8GVM9 PTHR40389:SF3 ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED IGE-BINDING PROTEIN MONDO|Ensembl=ENSMODG00000001305.4|UniProtKB=F7BZK3 F7BZK3 MGST3 PTHR10250:SF26 MICROSOMAL GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL glutathione transferase activity#GO:0004364;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;oxidoreductase activity#GO:0016491 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle envelope#GO:0031967;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transferase#PC00220 MONDO|Ensembl=ENSMODG00000020367.4|UniProtKB=F7FJP7 F7FJP7 IL7R PTHR23037:SF27 CYTOKINE RECEPTOR INTERLEUKIN-7 RECEPTOR SUBUNIT ALPHA transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 hemopoiesis#GO:0030097;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;anatomical structure development#GO:0048856;cell communication#GO:0007154;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cytokine-mediated signaling pathway#GO:0019221;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;interleukin-7-mediated signaling pathway#GO:0038111;cell surface receptor signaling pathway#GO:0007166;cell development#GO:0048468;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006745.2|UniProtKB=F7CD53 F7CD53 EARS2 PTHR43311:SF2 GLUTAMATE--TRNA LIGASE NONDISCRIMINATING GLUTAMYL-TRNA SYNTHETASE EARS2, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 aminoacyl-tRNA synthetase#PC00047 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 MONDO|Ensembl=ENSMODG00000008288.2|UniProtKB=F6YIH7 F6YIH7 DUSP2 PTHR10159:SF109 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 2 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cell communication#GO:0007154;anatomical structure development#GO:0048856;negative regulation of response to stimulus#GO:0048585;tissue development#GO:0009888;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;gastrulation#GO:0007369;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of signaling#GO:0023057;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;formation of primary germ layer#GO:0001704;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;embryo development#GO:0009790;endoderm formation#GO:0001706;regulation of MAPK cascade#GO:0043408;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;endoderm development#GO:0007492;anatomical structure formation involved in morphogenesis#GO:0048646 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000012777.4|UniProtKB=F6S1H5 F6S1H5 NEUROD2 PTHR19290:SF83 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000013678.4|UniProtKB=F6QPT8 F6QPT8 CEP164 PTHR18902:SF27 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED CENTROSOMAL PROTEIN OF 164 KDA plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ciliary transition fiber#GO:0097539;microtubule cytoskeleton#GO:0015630;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000021532.3|UniProtKB=F7E0A2 F7E0A2 IRF2BP1 PTHR10816:SF17 MYELIN TRANSCRIPTION FACTOR 1-RELATED INTERFERON REGULATORY FACTOR 2-BINDING PROTEIN 1 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000003738.3|UniProtKB=F7EDA0 F7EDA0 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000036622.1|UniProtKB=A0A5F8GSW5 A0A5F8GSW5 CHMP5 PTHR22761:SF12 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 5 late endosome to vacuole transport#GO:0045324;membrane assembly#GO:0071709;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endosomal transport#GO:0016197;vesicle budding from membrane#GO:0006900;nuclear envelope organization#GO:0006998;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907 vesicle membrane#GO:0012506;membrane#GO:0016020;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000019803.4|UniProtKB=H9H7H1 H9H7H1 HNRNPA3 PTHR48026:SF12 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A3 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000037733.1|UniProtKB=A0A5F8GFD1 A0A5F8GFD1 PTHR23262:SF186 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 1-1 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000021150.4|UniProtKB=A0A5F8G1P2 A0A5F8G1P2 PTHR11407:SF32 LYSOZYME C ALPHA-LACTALBUMIN lysozyme activity#GO:0003796;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824 glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000018954.4|UniProtKB=F7G0F6 F7G0F6 RSPH9 PTHR22069:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN S18 RADIAL SPOKE HEAD PROTEIN 9 HOMOLOG cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578 axoneme#GO:0005930;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000049788.1|UniProtKB=A0A5F8H7N9 A0A5F8H7N9 LOC100027553 PTHR26452:SF52 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000011642.3|UniProtKB=F6TJ83 F6TJ83 IDH3A PTHR11835:SF34 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652 dehydrogenase#PC00092;oxidoreductase#PC00176 Leucine biosynthesis#P02749>3-Isopropylmalate dehydrogenase#P03001 MONDO|Ensembl=ENSMODG00000007754.3|UniProtKB=F7BJD4 F7BJD4 STARD10 PTHR19308:SF7 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN START DOMAIN-CONTAINING PROTEIN 10 membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell-cell junction#GO:0005911;cytosol#GO:0005829;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;microvillus#GO:0005902 MONDO|Ensembl=ENSMODG00000006263.4|UniProtKB=F7FE19 F7FE19 TOR1AIP1 PTHR18843:SF6 TORSIN-1A-INTERACTING PROTEIN TORSIN-1A-INTERACTING PROTEIN 1 nuclear envelope organization#GO:0006998;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;cellular component organization#GO:0016043;organelle organization#GO:0006996 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear membrane#GO:0031965;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane#GO:0016020;organelle envelope#GO:0031967;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000025398.3|UniProtKB=F6S6Y0 F6S6Y0 ARL14EPL PTHR46804:SF4 ADP RIBOSYLATION FACTOR LIKE GTPASE 14 EFFECTOR PROTEIN LIKE ARL14 EFFECTOR PROTEIN-LIKE small GTPase#PC00208;G-protein#PC00020;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000014372.4|UniProtKB=A0A5F8H3R6 A0A5F8H3R6 CD163 PTHR19331:SF491 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M160 cargo receptor activity#GO:0038024 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000010797.3|UniProtKB=F7CI96 F7CI96 CX3CR1 PTHR10489:SF955 CELL ADHESION MOLECULE CX3C CHEMOKINE RECEPTOR 1 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;chemotaxis#GO:0006935;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000028665.1|UniProtKB=K7E0C4 K7E0C4 FBXO46 PTHR16271:SF10 F-BOX ONLY PROTEIN 34/46 FAMILY MEMBER F-BOX ONLY PROTEIN 46 MONDO|Ensembl=ENSMODG00000046065.1|UniProtKB=A0A5F8HL03 A0A5F8HL03 SNCG PTHR13820:SF10 SYNUCLEIN GAMMA-SYNUCLEIN transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 synaptic vesicle cycle#GO:0099504;transport#GO:0006810;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;cellular localization#GO:0051641;localization#GO:0051179;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;cellular component organization#GO:0016043;synaptic vesicle endocytosis#GO:0048488;regulation of biological process#GO:0050789;cell junction organization#GO:0034330;endocytosis#GO:0006897;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052 axon#GO:0030424;intracellular anatomical structure#GO:0005622;cell body#GO:0044297;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;neuron projection terminus#GO:0044306;neuronal cell body#GO:0043025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;axon terminus#GO:0043679;cell junction#GO:0030054;neuron projection#GO:0043005;presynapse#GO:0098793;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 Parkinson disease#P00049>gamma-Synuclein#P01231 MONDO|Ensembl=ENSMODG00000047682.1|UniProtKB=A0A5F8H7D2 A0A5F8H7D2 MSANTD4 PTHR21732:SF0 MYB/SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 4 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 4 MONDO|Ensembl=ENSMODG00000017340.4|UniProtKB=F6WFK2 F6WFK2 PTHR12155:SF29 SCHLAFEN SCHLAFEN-LIKE PROTEIN 1 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000045544.1|UniProtKB=A0A5F8H0T4 A0A5F8H0T4 PTHR12184:SF1 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 FAMILY MEMBER UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000020647.4|UniProtKB=A0A5F8GAB7 A0A5F8GAB7 USP46 PTHR24006:SF714 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 46 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000013914.4|UniProtKB=A0A5F8G6Y5 A0A5F8G6Y5 ELMO2 PTHR12771:SF8 ENGULFMENT AND CELL MOTILITY ENGULFMENT AND CELL MOTILITY PROTEIN 2 cellular response to chemical stimulus#GO:0070887;chemotaxis#GO:0006935;actin filament-based process#GO:0030029;cell chemotaxis#GO:0060326;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;locomotion#GO:0040011;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular process#GO:0009987;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>ELMO#P00917 MONDO|Ensembl=ENSMODG00000001311.4|UniProtKB=F7BEL2 F7BEL2 DDX20 PTHR47958:SF89 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX20-RELATED helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657 protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;SMN complex#GO:0032797;protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;cellular anatomical structure#GO:0110165 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000042930.1|UniProtKB=A0A5F8GB43 A0A5F8GB43 GLCE PTHR13174:SF3 D-GLUCURONYL C5-EPIMERASE D-GLUCURONYL C5-EPIMERASE isomerase activity#GO:0016853;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857 biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 isomerase#PC00135 MONDO|Ensembl=ENSMODG00000006851.4|UniProtKB=F6PFR6 F6PFR6 METTL17 PTHR21320:SF3 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED RIBOSOME ASSEMBLY PROTEIN METTL17, MITOCHONDRIAL chaperone#PC00072 MONDO|Ensembl=ENSMODG00000013820.4|UniProtKB=F6SF10 F6SF10 WNT9A PTHR12027:SF75 WNT RELATED PROTEIN WNT-9A molecular function activator activity#GO:0140677;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 signaling#GO:0023052;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;system development#GO:0048731;cell fate commitment#GO:0045165;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 MONDO|Ensembl=ENSMODG00000004349.4|UniProtKB=A0A5F8G519 A0A5F8G519 PTHR11738:SF199 MHC CLASS I NK CELL RECEPTOR IG-LIKE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000028858.2|UniProtKB=F6T2J6 F6T2J6 EIF2A PTHR13227:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 2A EUKARYOTIC TRANSLATION INITIATION FACTOR 2A translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 Gonadotropin-releasing hormone receptor pathway#P06664>EIF2A#P06762 MONDO|Ensembl=ENSMODG00000001023.4|UniProtKB=F7AY59 F7AY59 ADORA1 PTHR24246:SF1 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447;cell junction#GO:0030054 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 MONDO|Ensembl=ENSMODG00000017665.4|UniProtKB=A0A5F8GNU3 A0A5F8GNU3 UBE2L3 PTHR24068:SF67 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 L3 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein K11-linked ubiquitination#GO:0070979;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Parkinson disease#P00049>UbcH7#P01224 MONDO|Ensembl=ENSMODG00000020992.4|UniProtKB=A0A5F8GCL8 A0A5F8GCL8 NCAM2 PTHR12231:SF231 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN NEURAL CELL ADHESION MOLECULE 2 cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;protein binding#GO:0005515 developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection development#GO:0031175;axon development#GO:0061564;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;generation of neurons#GO:0048699;cell recognition#GO:0008037;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;cellular component organization#GO:0016043;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000049369.1|UniProtKB=A0A5F8GHW3 A0A5F8GHW3 PTHR10807:SF39 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 10 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000048435.1|UniProtKB=A0A5F8HF38 A0A5F8HF38 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000001832.4|UniProtKB=F6T527 F6T527 NUCKS1 PTHR15361:SF1 RAD51/NUKS-INTERACTING PROTEIN NUCLEAR UBIQUITOUS CASEIN AND CYCLIN-DEPENDENT KINASE SUBSTRATE 1 DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697 cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular process#GO:0009987;response to stress#GO:0006950;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000039258.1|UniProtKB=A0A5F8GQQ4 A0A5F8GQQ4 monDomV1R1287 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011643.5|UniProtKB=F6TJ54 F6TJ54 MECP2 PTHR15074:SF6 METHYL-CPG-BINDING PROTEIN METHYL-CPG-BINDING PROTEIN 2 sequence-specific DNA binding#GO:0043565;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;chromatin binding#GO:0003682;nucleoside phosphate binding#GO:1901265;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000025682.3|UniProtKB=F6U066 F6U066 TNFSF13 PTHR15151:SF12 PROTEIN EIGER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;immune system process#GO:0002376;regulation of DNA recombination#GO:0000018;regulation of lymphocyte mediated immunity#GO:0002706;regulation of lymphocyte activation#GO:0051249;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;positive regulation of leukocyte activation#GO:0002696;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of B cell activation#GO:0050864;positive regulation of immune system process#GO:0002684;positive regulation of lymphocyte mediated immunity#GO:0002708;positive regulation of lymphocyte activation#GO:0051251;positive regulation of biosynthetic process#GO:0009891;regulation of immune effector process#GO:0002697;regulation of immune response#GO:0050776;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of DNA metabolic process#GO:0051054;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;positive regulation of developmental process#GO:0051094;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000021426.4|UniProtKB=A0A5F8GPS7 A0A5F8GPS7 SPIRE1 PTHR21345:SF8 SPIRE PROTEIN SPIRE HOMOLOG 1 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 Golgi vesicle transport#GO:0048193;membrane invagination#GO:0010324;meiotic cell cycle#GO:0051321;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;cytokinetic process#GO:0032506;nuclear division#GO:0000280;cytokinesis#GO:0000910;cellular localization#GO:0051641;spindle localization#GO:0051653;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;establishment of organelle localization#GO:0051656;gamete generation#GO:0007276;transport#GO:0006810;intracellular transport#GO:0046907;actin filament organization#GO:0007015;meiotic nuclear division#GO:0140013;establishment of localization#GO:0051234;establishment of spindle localization#GO:0051293;membrane organization#GO:0061024;actin filament-based process#GO:0030029;sexual reproduction#GO:0019953;organelle localization#GO:0051640;multicellular organismal reproductive process#GO:0048609;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;localization#GO:0051179;cell division#GO:0051301;cell cycle#GO:0007049;reproductive process#GO:0022414;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000013527.3|UniProtKB=F7D6Q4 F7D6Q4 CDKN1A PTHR46778:SF1 CYCLIN-DEPENDENT KINASE INHIBITOR 1-RELATED CYCLIN-DEPENDENT KINASE INHIBITOR 1 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;kinase inhibitor activity#GO:0019210;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887 DNA damage response#GO:0006974;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;response to stress#GO:0006950;regulation of mitotic cell cycle phase transition#GO:1901990;cellular response to stress#GO:0033554;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;nucleus#GO:0005634;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 kinase inhibitor#PC00139 Interleukin signaling pathway#P00036>p21CIP1#P00993;p53 pathway feedback loops 2#P04398>P21#G04712;p53 pathway#P00059>P21#P04631;p53 pathway#P00059>p21#G01580;p53 pathway feedback loops 2#P04398>p21#P04667 MONDO|Ensembl=ENSMODG00000038472.1|UniProtKB=A0A5F8H4V5 A0A5F8H4V5 LOC100024733 PTHR26454:SF77 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000050050.1|UniProtKB=A0A5F8HAE4 A0A5F8HAE4 PTHR10026:SF43 CYCLIN CYCLIN-T2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 regulation of DNA-templated transcription elongation#GO:0032784;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 transferase complex#GO:1990234;protein kinase complex#GO:1902911;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 kinase activator#PC00138;kinase modulator#PC00140 MONDO|Ensembl=ENSMODG00000037427.1|UniProtKB=A0A5F8GIX1 A0A5F8GIX1 NT5C3A PTHR13045:SF14 5'-NUCLEOTIDASE CYTOSOLIC 5'-NUCLEOTIDASE 3A catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;esterase#PC00097 MONDO|Ensembl=ENSMODG00000007736.4|UniProtKB=F7C463 F7C463 SERAC1 PTHR48182:SF2 PROTEIN SERAC1 PROTEIN SERAC1 MONDO|Ensembl=ENSMODG00000018449.4|UniProtKB=F7CUE5 F7CUE5 SLC25A18 PTHR45678:SF11 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED MITOCHONDRIAL GLUTAMATE CARRIER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000018005.4|UniProtKB=F7AL53 F7AL53 NR2E1 PTHR24083:SF98 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP E MEMBER 1 transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000007958.3|UniProtKB=F7E9X3 F7E9X3 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000000667.4|UniProtKB=F6SBB8 F6SBB8 PTHR23037:SF30 CYTOKINE RECEPTOR INTERLEUKIN-2 RECEPTOR SUBUNIT BETA binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;growth factor binding#GO:0019838;coreceptor activity#GO:0015026;cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;interleukin-2-mediated signaling pathway#GO:0038110;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to peptide#GO:1901652;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974 MONDO|Ensembl=ENSMODG00000009274.4|UniProtKB=A0A5F8HIX5 A0A5F8HIX5 IKZF1 PTHR24404:SF36 ZINC FINGER PROTEIN DNA-BINDING PROTEIN IKAROS sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000012947.4|UniProtKB=F7G3Z6 F7G3Z6 GRAMD1B PTHR23319:SF3 GRAM DOMAIN CONTAINING 1B, ISOFORM E PROTEIN ASTER-B sterol transfer activity#GO:0120015;transporter activity#GO:0005215;steroid binding#GO:0005496;alcohol binding#GO:0043178;cholesterol transfer activity#GO:0120020;sterol binding#GO:0032934;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;small molecule binding#GO:0036094;binding#GO:0005488;lipid transfer activity#GO:0120013;cholesterol binding#GO:0015485;lipid binding#GO:0008289 organic hydroxy compound transport#GO:0015850;cellular localization#GO:0051641;sterol transport#GO:0015918;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907;lipid localization#GO:0010876;intracellular sterol transport#GO:0032366;lipid transport#GO:0006869;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036 plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;organelle membrane contact site#GO:0044232;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000040030.1|UniProtKB=A0A5F8GLC1 A0A5F8GLC1 CYB5D1 PTHR21281:SF1 CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1 CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1 cellular process#GO:0009987;cilium movement#GO:0003341;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 MONDO|Ensembl=ENSMODG00000021546.4|UniProtKB=A0A5F8H8I1 A0A5F8H8I1 PTHR12749:SF0 EXCISION REPAIR CROSS-COMPLEMENTING 1 ERCC1 DNA EXCISION REPAIR PROTEIN ERCC-1 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697 cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;response to UV#GO:0009411;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to abiotic stimulus#GO:0071214;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;nucleic acid metabolic process#GO:0090304;cellular response to radiation#GO:0071478;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to stress#GO:0033554;mitotic recombination#GO:0006312 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleotide-excision repair complex#GO:0000109;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 endodeoxyribonuclease#PC00093 MONDO|Ensembl=ENSMODG00000001285.4|UniProtKB=F7C0B8 F7C0B8 CACHD1 PTHR10166:SF68 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VWFA AND CACHE DOMAIN-CONTAINING PROTEIN 1 channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;calcium channel complex#GO:0034704;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 voltage-gated ion channel#PC00241;transporter#PC00227 MONDO|Ensembl=ENSMODG00000017618.5|UniProtKB=F6ZTB3 F6ZTB3 AKAP6 PTHR14514:SF2 PKA ANCHORING PROTEIN A-KINASE ANCHOR PROTEIN 6 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of monoatomic ion transport#GO:0043269;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of system process#GO:0044057;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of membrane potential#GO:0042391;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762;regulation of muscle system process#GO:0090257;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;regulation of biological quality#GO:0065008 endoplasmic reticulum#GO:0005783;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;sarcoplasmic reticulum#GO:0016529;nucleus#GO:0005634;membrane#GO:0016020;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;sarcoplasm#GO:0016528;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000020902.4|UniProtKB=A0A5F8GUN8 A0A5F8GUN8 ACSF2 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 ligase#PC00142;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000004798.4|UniProtKB=F6VM95 F6VM95 PTHR14063:SF1 PROTEIN LIN-7 HOMOLOG PDZ DOMAIN-CONTAINING PROTEIN 11 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 transport#GO:0006810;establishment of localization#GO:0051234;vesicle localization#GO:0051648;regulation of synapse assembly#GO:0051963;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;organelle localization#GO:0051640;regulation of cell junction assembly#GO:1901888;localization#GO:0051179;cell communication#GO:0007154;regulation of synapse structure or activity#GO:0050803;secretion#GO:0046903;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of growth#GO:0040008;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;synaptic vesicle transport#GO:0048489;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;synaptic vesicle localization#GO:0097479;neurotransmitter transport#GO:0006836;establishment of vesicle localization#GO:0051650;regulation of synapse organization#GO:0050807;cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;establishment of organelle localization#GO:0051656;signaling#GO:0023052;export from cell#GO:0140352;regulation of cellular component biogenesis#GO:0044087 cell junction#GO:0030054;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000039995.1|UniProtKB=A0A5F8G547 A0A5F8G547 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011780.2|UniProtKB=A0A5F8GGH0 A0A5F8GGH0 ABHD14A PTHR46197:SF1 PROTEIN ABHD14B-LIKE PROTEIN ABHD14A intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000050743.1|UniProtKB=A0A5F8GE73 A0A5F8GE73 LOC100030225 PTHR26453:SF238 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10N1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025197.1|UniProtKB=F7BG52 F7BG52 PTHR11787:SF1 RAB GDP-DISSOCIATION INHIBITOR RAB GDP DISSOCIATION INHIBITOR BETA GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000015433.4|UniProtKB=F6SLT9 F6SLT9 RASGRP3 PTHR23113:SF178 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 3 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>CalDAG-GEF#P00736 MONDO|Ensembl=ENSMODG00000006865.5|UniProtKB=A0A5F8GYZ4 A0A5F8GYZ4 PTHR23251:SF2 LYSINE-RICH CEACAM1 CO-ISOLATED PROTEIN LYRIC PROTEIN METADHERIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000020854.4|UniProtKB=F6R0P4 F6R0P4 CLASRP PTHR13161:SF4 SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT CLK4-ASSOCIATING SERINE_ARGININE RICH PROTEIN mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000006423.3|UniProtKB=F7EZK3 F7EZK3 PTHR32035:SF3 AURORA KINASE A-INTERACTING PROTEIN SMALL RIBOSOMAL SUBUNIT PROTEIN BS22, MITOCHONDRIAL MONDO|Ensembl=ENSMODG00000003367.2|UniProtKB=F6ZPM9 F6ZPM9 LOC100016394 PTHR48018:SF157 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012444.2|UniProtKB=A0A5F8HFR6 A0A5F8HFR6 PTHR12471:SF2 VACUOLAR ATP SYNTHASE SUBUNIT S1 V-TYPE PROTON ATPASE SUBUNIT S1 regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;homeostatic process#GO:0042592 ATPase dependent transmembrane transport complex#GO:0098533;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cation-transporting ATPase complex#GO:0090533;membrane#GO:0016020;membrane protein complex#GO:0098796 primary active transporter#PC00068;ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000040442.1|UniProtKB=A0A5F8GFX7 A0A5F8GFX7 SPCS3 PTHR12804:SF0 MICROSOMAL SIGNAL PEPTIDASE 23 KD SUBUNIT SPC22/23 SIGNAL PEPTIDASE COMPLEX SUBUNIT 3 localization#GO:0051179;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein targeting#GO:0006605;metabolic process#GO:0008152;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of protein localization to endoplasmic reticulum#GO:0072599;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;peptidase complex#GO:1905368;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 protease#PC00190 Vasopressin synthesis#P04395>Signal Peptidase#P04589 MONDO|Ensembl=ENSMODG00000000135.4|UniProtKB=F6YB00 F6YB00 RTF1 PTHR13115:SF8 RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000051059.1|UniProtKB=A0A5F8GJU2 A0A5F8GJU2 CKM PTHR11547:SF63 ARGININE OR CREATINE KINASE CREATINE KINASE M-TYPE phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 modified amino acid metabolic process#GO:0006575;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;amino acid kinase#PC00045 MONDO|Ensembl=ENSMODG00000040195.1|UniProtKB=A0A5F8G9J3 A0A5F8G9J3 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000015600.3|UniProtKB=F6Z679 F6Z679 ZNF512 PTHR22979:SF2 ZINC FINGER PROTEIN-RELATED ZINC FINGER PROTEIN 512 MONDO|Ensembl=ENSMODG00000001833.3|UniProtKB=F6T523 F6T523 MTIF2 PTHR43381:SF20 TRANSLATION INITIATION FACTOR IF-2-RELATED TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000013408.4|UniProtKB=A0A5F8GYX0 A0A5F8GYX0 NUP93 PTHR11225:SF4 NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN NUCLEAR PORE COMPLEX PROTEIN NUP93 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;biosynthetic process#GO:0009058;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;gene expression#GO:0010467;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;protein import into nucleus#GO:0006606;protein transport#GO:0015031;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641 organelle envelope#GO:0031967;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 MONDO|Ensembl=ENSMODG00000024361.2|UniProtKB=F7AI02 F7AI02 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001071.3|UniProtKB=F6YQJ2 F6YQJ2 TIGD4 PTHR19303:SF18 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000049668.1|UniProtKB=K7E5K8 K7E5K8 LOC100019194 PTHR12960:SF0 GLE-1-RELATED MRNA EXPORT FACTOR GLE1 phospholipid binding#GO:0005543;translation initiation factor binding#GO:0031369;alcohol binding#GO:0043178;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;protein binding#GO:0005515;lipid binding#GO:0008289 establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;transport#GO:0006810;gene expression#GO:0010467;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 translation factor#PC00223 MONDO|Ensembl=ENSMODG00000009591.4|UniProtKB=F7A9F7 F7A9F7 HOXD9 PTHR45970:SF4 AGAP004664-PA HOMEOBOX PROTEIN HOX-D9 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;skeletal system morphogenesis#GO:0048705;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;skeletal system development#GO:0001501;embryo development#GO:0009790;anterior/posterior pattern specification#GO:0009952;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000051236.1|UniProtKB=A0A5F8HI72 A0A5F8HI72 PTHR11394:SF55 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 4 signaling receptor activity#GO:0038023;taste receptor activity#GO:0008527;bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;sensory perception of taste#GO:0050909;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011165.5|UniProtKB=F6ZZU0 F6ZZU0 CNNM2 PTHR12064:SF22 METAL TRANSPORTER CNNM METAL TRANSPORTER CNNM2 magnesium ion transmembrane transporter activity#GO:0015095;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873 homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000029647.2|UniProtKB=K7E0N5 K7E0N5 PTHR33064:SF44 POL PROTEIN RIBONUCLEASE H MONDO|Ensembl=ENSMODG00000018294.3|UniProtKB=F6PW63 F6PW63 PTHR10388:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 EUKARYOTIC TRANSLATION INITIATION FACTOR 1 translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribonucleoprotein complex#GO:1990904 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000014321.4|UniProtKB=F6W3V0 F6W3V0 SMPD4 PTHR12988:SF6 SPHINGOMYELIN PHOSPHODIESTERASE 4 SPHINGOMYELIN PHOSPHODIESTERASE 4 phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;lipase activity#GO:0016298;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 glycerolipid catabolic process#GO:0046503;ceramide metabolic process#GO:0006672;organophosphate catabolic process#GO:0046434;sphingolipid catabolic process#GO:0030149;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;glycerophospholipid catabolic process#GO:0046475;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042;lipid biosynthetic process#GO:0008610;sphingomyelin metabolic process#GO:0006684;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058 phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000002385.4|UniProtKB=F7F019 F7F019 PTHR11890:SF6 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-18 RECEPTOR 1 cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;adaptive immune response#GO:0002250;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;cytokine-mediated signaling pathway#GO:0019221;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to peptide#GO:1901652;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of multicellular organismal process#GO:0051240;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007983.4|UniProtKB=F7D5R8 F7D5R8 PROM2 PTHR22730:SF6 PROMININ PROM PROTEIN PROMININ-2 cellular process#GO:0009987;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840 plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;microvillus#GO:0005902;actin-based cell projection#GO:0098858;apical plasma membrane#GO:0016324;actin cytoskeleton#GO:0015629;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000004679.4|UniProtKB=F6U6J8 F6U6J8 RAD18 PTHR14134:SF2 E3 UBIQUITIN-PROTEIN LIGASE RAD18 E3 UBIQUITIN-PROTEIN LIGASE RAD18 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 DNA damage tolerance#GO:0006301;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000041105.1|UniProtKB=A0A5F8GWD4 A0A5F8GWD4 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000006846.4|UniProtKB=F6PFT6 F6PFT6 RAB37 PTHR47978:SF64 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-37 guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of secretion#GO:0051046 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000012749.4|UniProtKB=A0A5F8GNK3 A0A5F8GNK3 SHCBP1 PTHR14695:SF8 SHC SH2-DOMAIN BINDING PROTEIN 1-RELATED SHC SH2 DOMAIN-BINDING PROTEIN 1 sexual reproduction#GO:0019953;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;organelle fission#GO:0048285;enzyme-linked receptor protein signaling pathway#GO:0007167;multicellular organismal reproductive process#GO:0048609;cell cycle#GO:0007049;developmental process involved in reproduction#GO:0003006;cellular response to stimulus#GO:0051716;cell division#GO:0051301;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;response to fibroblast growth factor#GO:0071774;spermatogenesis#GO:0007283;developmental process#GO:0032502;meiotic nuclear division#GO:0140013;fibroblast growth factor receptor signaling pathway#GO:0008543;male gamete generation#GO:0048232;biological regulation#GO:0065007;nuclear division#GO:0000280;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;gamete generation#GO:0007276;signaling#GO:0023052;meiotic cell cycle#GO:0051321;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;male meiotic nuclear division#GO:0007140 MONDO|Ensembl=ENSMODG00000049889.1|UniProtKB=A0A5F8HKK1 A0A5F8HKK1 ARID3C PTHR15348:SF2 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3C binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000016507.4|UniProtKB=F7EQH9 F7EQH9 RNLS PTHR23357:SF1 RENALASE RENALASE catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000014873.4|UniProtKB=F6YKT7 F6YKT7 PBX2 PTHR11850:SF50 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 2 transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 sensory system development#GO:0048880;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;head development#GO:0060322;embryo development#GO:0009790;nervous system development#GO:0007399;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;neuron development#GO:0048666;eye development#GO:0001654;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;visual system development#GO:0150063;embryonic organ development#GO:0048568;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000009530.3|UniProtKB=F7C4A1 F7C4A1 CD8B PTHR11292:SF7 T-CELL SURFACE GLYCOPROTEIN CD8 BETA CHAIN T-CELL SURFACE GLYCOPROTEIN CD8 BETA CHAIN-RELATED immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000019763.4|UniProtKB=F6WMN8 F6WMN8 RABEPK PTHR46647:SF1 RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS MONDO|Ensembl=ENSMODG00000016789.2|UniProtKB=F7G683 F7G683 NKX3-1 PTHR24340:SF38 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-3.1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000012508.3|UniProtKB=F6Q1G3 F6Q1G3 ACTR8 PTHR11937:SF13 ACTIN ACTIN-RELATED PROTEIN 8 structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;structural molecule activity#GO:0005198 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to stress#GO:0033554;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;regulation of gene expression#GO:0010468;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 Ino80 complex#GO:0031011;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000037644.1|UniProtKB=A0A5F8GTL7 A0A5F8GTL7 SARS2 PTHR11778:SF23 SERYL-TRNA SYNTHETASE SERINE--TRNA LIGASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;RNA binding#GO:0003723 tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;translation#GO:0006412;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000005705.3|UniProtKB=F7A9C7 F7A9C7 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000050434.1|UniProtKB=A0A5F8GP03 A0A5F8GP03 MT4 PTHR23299:SF12 METALLOTHIONEIN METALLOTHIONEIN-4 metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 detoxification of inorganic compound#GO:0061687;monoatomic ion homeostasis#GO:0050801;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;detoxification#GO:0098754;response to cadmium ion#GO:0046686;response to metal ion#GO:0010038;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic ion homeostasis#GO:0006873;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;homeostatic process#GO:0042592;cellular response to chemical stimulus#GO:0070887;inorganic ion homeostasis#GO:0098771 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000007485.3|UniProtKB=F7CQY7 F7CQY7 CABP4 PTHR45917:SF4 CALCIUM-BINDING PROTEIN 1-RELATED CALCIUM-BINDING PROTEIN 4 transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;sensory perception of light stimulus#GO:0050953;signaling#GO:0023052;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;visual perception#GO:0007601;sensory perception of sound#GO:0007605;regulation of cellular process#GO:0050794;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;nervous system process#GO:0050877;cell communication#GO:0007154;signal transduction#GO:0007165;response to radiation#GO:0009314;cellular process#GO:0009987;detection of stimulus#GO:0051606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;response to external stimulus#GO:0009605;system process#GO:0003008 MONDO|Ensembl=ENSMODG00000003415.4|UniProtKB=F7GKM8 F7GKM8 MBD5 PTHR16112:SF18 METHYL-CPG BINDING PROTEIN, DROSOPHILA METHYL-CPG-BINDING DOMAIN PROTEIN 5 chromatin binding#GO:0003682;binding#GO:0005488 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000007141.3|UniProtKB=F6RZ22 F6RZ22 LOC100016032 PTHR43917:SF4 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE THETA-2-RELATED transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220 MONDO|Ensembl=ENSMODG00000044246.1|UniProtKB=K7DZL1 K7DZL1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000004232.3|UniProtKB=F6UBS0 F6UBS0 HYLS1 PTHR34174:SF1 HYDROLETHALUS SYNDROME PROTEIN 1 CENTRIOLAR AND CILIOGENESIS-ASSOCIATED PROTEIN HYLS1 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000045960.1|UniProtKB=A0A5F8GDK1 A0A5F8GDK1 LOC130458906 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000010723.3|UniProtKB=F7G7L6 F7G7L6 BAG4 PTHR12329:SF10 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 4 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 regulation of protein stability#GO:0031647;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;nucleus#GO:0005634 chaperone#PC00072 Apoptosis signaling pathway#P00006>SODD#P00320 MONDO|Ensembl=ENSMODG00000003334.4|UniProtKB=A0A5F8GER5 A0A5F8GER5 PTHR45706:SF3 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 21 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000046191.1|UniProtKB=A0A5F8GS39 A0A5F8GS39 HVCN1 PTHR46480:SF1 F20B24.22 VOLTAGE-GATED HYDROGEN CHANNEL 1 passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000024648.3|UniProtKB=F6SKB9 F6SKB9 PIGG PTHR23072:SF0 PHOSPHATIDYLINOSITOL GLYCAN-RELATED GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 2, CATALYTIC SUBUNIT transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity#GO:0016740;catalytic activity#GO:0003824 phospholipid metabolic process#GO:0006644;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;gene expression#GO:0010467;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;carbohydrate derivative metabolic process#GO:1901135;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organophosphate metabolic process#GO:0019637;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000012594.5|UniProtKB=F6PI99 F6PI99 CCDC92 PTHR14882:SF4 COILED-COIL DOMAIN-CONTAINING 74A COILED-COIL DOMAIN-CONTAINING PROTEIN 92 cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization#GO:0016043;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;positive regulation of response to external stimulus#GO:0032103;cellular component organization or biogenesis#GO:0071840;immune response-activating signaling pathway#GO:0002757;protein-containing complex organization#GO:0043933;regulation of response to external stimulus#GO:0032101;cellular component assembly#GO:0022607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;inflammatory response#GO:0006954;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to biotic stimulus#GO:0002831;intracellular receptor signaling pathway#GO:0030522;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of innate immune response#GO:0045088;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000004419.4|UniProtKB=F6SD73 F6SD73 ZMYM3 PTHR45736:SF3 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 3 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000011308.3|UniProtKB=F6WJE3 F6WJE3 DNAAF19 PTHR28572:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 103 DYNEIN AXONEMAL ASSEMBLY FACTOR 19 cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;inner dynein arm assembly#GO:0036159;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;determination of bilateral symmetry#GO:0009855;left/right pattern formation#GO:0060972;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;determination of left/right symmetry#GO:0007368;organelle assembly#GO:0070925;pattern specification process#GO:0007389;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;axoneme assembly#GO:0035082;regionalization#GO:0003002;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;specification of symmetry#GO:0009799;developmental process#GO:0032502 MONDO|Ensembl=ENSMODG00000006573.4|UniProtKB=F7B818 F7B818 POLR1B PTHR20856:SF5 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA2 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;transcription by RNA polymerase I#GO:0006360;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;RNA polymerase I complex#GO:0005736;catalytic complex#GO:1902494;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 MONDO|Ensembl=ENSMODG00000006293.3|UniProtKB=F7CAE5 F7CAE5 SYNDIG1 PTHR14768:SF3 UPF0338 PROTEIN SYNAPSE DIFFERENTIATION-INDUCING GENE PROTEIN 1 regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;localization#GO:0051179;organelle localization#GO:0051640;regulation of cell junction assembly#GO:1901888;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;establishment of localization#GO:0051234;positive regulation of synapse assembly#GO:0051965;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;positive regulation of developmental process#GO:0051094;regulation of synapse assembly#GO:0051963;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;vesicle localization#GO:0051648;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;regulation of synapse organization#GO:0050807;positive regulation of cellular component organization#GO:0051130;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;vesicle-mediated transport in synapse#GO:0099003;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;positive regulation of cellular component biogenesis#GO:0044089;regulation of multicellular organismal process#GO:0051239;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649 organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;transport vesicle#GO:0030133;neuron to neuron synapse#GO:0098984;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;plasma membrane#GO:0005886;postsynaptic density#GO:0014069;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;postsynaptic density membrane#GO:0098839;cytoplasmic vesicle#GO:0031410;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;asymmetric synapse#GO:0032279;intracellular membrane-bounded organelle#GO:0043231;synaptic membrane#GO:0097060;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;secretory vesicle#GO:0099503;presynapse#GO:0098793;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular vesicle#GO:0097708;postsynapse#GO:0098794;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202 MONDO|Ensembl=ENSMODG00000010878.4|UniProtKB=F6Z3K8 F6Z3K8 LOC100618922 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000024493.3|UniProtKB=F7E383 F7E383 LOC103098338 PTHR11437:SF20 RIBONUCLEASE INACTIVE RIBONUCLEASE-LIKE PROTEIN 12-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to Gram-positive bacterium#GO:0050830;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617 RNA metabolism protein#PC00031;endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000001618.4|UniProtKB=A0A5F8GG80 A0A5F8GG80 POGK PTHR19303:SF57 TRANSPOSON POGO TRANSPOSABLE ELEMENT WITH KRAB DOMAIN binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000015796.3|UniProtKB=A0A5F8GGQ6 A0A5F8GGQ6 MIC-like PTHR16675:SF64 MHC CLASS I-RELATED RETINOIC ACID EARLY TRANSCRIPT 1E signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 regulation of leukocyte mediated immunity#GO:0002703;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte mediated immunity#GO:0002708;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;response to other organism#GO:0051707;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;cell killing#GO:0001906;positive regulation of leukocyte mediated immunity#GO:0002705;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;natural killer cell mediated immunity#GO:0002228;regulation of biological process#GO:0050789;leukocyte mediated cytotoxicity#GO:0001909;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of cell killing#GO:0031341;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;cellular process#GO:0009987;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;immune effector process#GO:0002252;natural killer cell mediated cytotoxicity#GO:0042267 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000013728.5|UniProtKB=F6XQM4 F6XQM4 ZNF335 PTHR24403:SF36 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 335 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;multicellular organismal process#GO:0032501;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;positive regulation of nervous system development#GO:0051962;central nervous system development#GO:0007417;chromatin remodeling#GO:0006338;animal gross anatomical part developmental process#GO:0160108;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of cell development#GO:0010720;head development#GO:0060322;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000007746.4|UniProtKB=A0A5F8H731 A0A5F8H731 CLYBL PTHR11105:SF0 CITRATE LYASE SUBUNIT BETA-RELATED CITRAMALYL-COA LYASE, MITOCHONDRIAL lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222 lyase#PC00144 Pyruvate metabolism#P02772>Citrate Lyase#P03137 MONDO|Ensembl=ENSMODG00000043915.1|UniProtKB=K7E5L2 K7E5L2 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000027964.2|UniProtKB=K7E4Y1 K7E4Y1 LOC100020571 PTHR42985:SF10 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 1 solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 sodium ion transport#GO:0006814;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;lipid localization#GO:0010876;localization#GO:0051179;monoatomic cation transport#GO:0006812;fatty acid transport#GO:0015908;transmembrane transport#GO:0055085;monocarboxylic acid transport#GO:0015718;monoatomic ion transport#GO:0006811;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000019703.3|UniProtKB=F6TC73 F6TC73 LOC100017083 PTHR48001:SF81 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 356 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007369.4|UniProtKB=F7ACW1 F7ACW1 PTHR10574:SF431 NETRIN/LAMININ-RELATED NETRIN-4 multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;substrate adhesion-dependent cell spreading#GO:0034446;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component assembly#GO:0022607;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;cellular process#GO:0009987;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;generation of neurons#GO:0048699;cell adhesion#GO:0007155;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;tissue development#GO:0009888;extracellular matrix assembly#GO:0085029;multicellular organismal process#GO:0032501;cell migration#GO:0016477;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411;cell-substrate adhesion#GO:0031589;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;system development#GO:0048731;external encapsulating structure organization#GO:0045229;cell motility#GO:0048870 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;basement membrane#GO:0005604 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000007712.2|UniProtKB=F7EUX9 F7EUX9 LOC100619599 PTHR48002:SF124 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001188.4|UniProtKB=F7GHB9 F7GHB9 PTHR15856:SF26 PHD FINGER PROTEIN 20-RELATED PHD FINGER PROTEIN 20-LIKE PROTEIN 1 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;NSL complex#GO:0044545;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000047136.1|UniProtKB=A0A5F8G3X8 A0A5F8G3X8 LOC100031268 PTHR26454:SF77 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001903.4|UniProtKB=F6W1S4 F6W1S4 CEP97 PTHR45973:SF2 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED CENTROSOMAL PROTEIN OF 97 KDA negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of cell projection assembly#GO:0060491;regulation of organelle assembly#GO:1902115;biological regulation#GO:0065007;regulation of cell projection organization#GO:0031344;regulation of cilium assembly#GO:1902017;negative regulation of cellular process#GO:0048523;regulation of plasma membrane bounded cell projection organization#GO:0120035 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000024448.4|UniProtKB=F7CF56 F7CF56 RBM23 PTHR48036:SF3 SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED RNA-BINDING PROTEIN 23-RELATED binding#GO:0005488;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021 regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000013749.4|UniProtKB=F6Z0T7 F6Z0T7 LOC100026597 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025732.2|UniProtKB=F6T259 F6T259 PTHR48002:SF50 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004535.4|UniProtKB=F6U9B0 F6U9B0 PABPN1 PTHR23236:SF16 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H POLYADENYLATE-BINDING PROTEIN 2 single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143;binding#GO:0005488 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000009537.4|UniProtKB=F6XGI9 F6XGI9 IGFBP1 PTHR11551:SF6 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 1 binding#GO:0005488;growth factor binding#GO:0019838;protein binding#GO:0005515 regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 PI3 kinase pathway#P00048>IGFBP1#G01543 MONDO|Ensembl=ENSMODG00000002401.3|UniProtKB=F7EHK1 F7EHK1 PTHR11890:SF23 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-18 RECEPTOR ACCESSORY PROTEIN molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016005.4|UniProtKB=F7EGE6 F7EGE6 ADAM23 PTHR11905:SF13 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 23 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000038594.1|UniProtKB=A0A5F8H4F0 A0A5F8H4F0 TNNC2 PTHR23064:SF72 TROPONIN TROPONIN C, SKELETAL MUSCLE actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000004835.1|UniProtKB=F6UL95 F6UL95 DR1 PTHR46138:SF1 PROTEIN DR1 PROTEIN DR1 protein binding#GO:0005515;binding#GO:0005488;transcription factor binding#GO:0008134 cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000005370.4|UniProtKB=F7EWL9 F7EWL9 LOC100016346 PTHR24377:SF980 IP01015P-RELATED ZINC FINGER PROTEIN 420 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000001887.4|UniProtKB=F7GB82 F7GB82 SLC26A9 PTHR11814:SF17 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 9 carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108 transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000001906.4|UniProtKB=F6W1P5 F6W1P5 EFCAB14 PTHR15717:SF2 PROTEIN KIAA0494 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 14 MONDO|Ensembl=ENSMODG00000018371.4|UniProtKB=F6RFS3 F6RFS3 SLC12A8 PTHR11827:SF6 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 8 chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;symporter activity#GO:0015293;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000008798.4|UniProtKB=F6QUY0 F6QUY0 GDI1 PTHR11787:SF3 RAB GDP-DISSOCIATION INHIBITOR RAB GDP DISSOCIATION INHIBITOR ALPHA GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein-binding activity modulator#PC00095;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000000636.4|UniProtKB=F6TAB2 F6TAB2 ZHX3 PTHR15467:SF6 ZINC-FINGERS AND HOMEOBOXES RELATED ZINC FINGERS AND HOMEOBOXES PROTEIN 3 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000014275.2|UniProtKB=F6X1G4 F6X1G4 LOC100013846 PTHR23239:SF110 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA7 structural molecule activity#GO:0005198 supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;intermediate filament organization#GO:0045109;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;morphogenesis of an epithelium#GO:0002009;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cytoskeleton organization#GO:0007010;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cellular process#GO:0009987;organelle organization#GO:0006996 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000028385.2|UniProtKB=K7E5M1 K7E5M1 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000007594.4|UniProtKB=F7CPB8 F7CPB8 MAP3K10 PTHR44329:SF39 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 10 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;biological regulation#GO:0065007;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of apoptotic process#GO:0042981;cell communication#GO:0007154;positive regulation of apoptotic process#GO:0043065 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Huntington disease#P00029>MLK-2#P00764;p38 MAPK pathway#P05918>MLK2#P06028 MONDO|Ensembl=ENSMODG00000013789.4|UniProtKB=F6TE70 F6TE70 DEF6 PTHR14383:SF2 SWAP-70 RECOMBINASE DIFFERENTIALLY EXPRESSED IN FDCP 6 HOMOLOG enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component assembly#GO:0022607;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;response to stimulus#GO:0050896;actin filament polymerization#GO:0030041;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;regulation of biological process#GO:0050789;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007226.4|UniProtKB=F6WCQ3 F6WCQ3 LOC100028093 PTHR45884:SF3 N-ACETYLTRANSFERASE ECO N-ACETYLTRANSFERASE ESCO2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746 cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitotic sister chromatid cohesion#GO:0007064;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000029316.2|UniProtKB=K7DYR3 K7DYR3 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000023139.2|UniProtKB=F7D9A3 F7D9A3 PTHR24034:SF193 EGF-LIKE DOMAIN-CONTAINING PROTEIN THROMBOMODULIN biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to transforming growth factor beta#GO:0071559 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000031892.2|UniProtKB=A0A5F8G4A8 A0A5F8G4A8 PTHR35825:SF2 CASEIN KINASE II SUBUNIT ALPHA PRIME-INTERACTING PROTEIN CASEIN KINASE II SUBUNIT ALPHA'-INTERACTING PROTEIN MONDO|Ensembl=ENSMODG00000016867.4|UniProtKB=F6Y263 F6Y263 RHBG PTHR11730:SF42 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER RH TYPE B channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 homeostatic process#GO:0042592;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000020961.4|UniProtKB=F6SNU6 F6SNU6 TMPRSS2 PTHR24253:SF89 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 2 serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000000336.4|UniProtKB=F6VDE6 F6VDE6 GAB1 PTHR45960:SF5 GRB2-ASSOCIATED-BINDING PROTEIN GRB2-ASSOCIATED-BINDING PROTEIN 1 signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Grb2#P01148;EGF receptor signaling pathway#P00018>Gab#P00563 MONDO|Ensembl=ENSMODG00000007269.4|UniProtKB=K7E0U2 K7E0U2 SLC6A6 PTHR11616:SF141 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT TAURINE TRANSPORTER chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;amino acid transmembrane transporter activity#GO:0015171;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000014484.3|UniProtKB=A0A5S8B500 A0A5S8B500 ADI1 PTHR23418:SF0 ACIREDUCTONE DIOXYGENASE ACIREDUCTONE DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;proteinogenic amino acid metabolic process#GO:0170039;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound metabolic process#GO:0072521;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000015572.4|UniProtKB=F7AIQ2 F7AIQ2 PLB1 PTHR21325:SF52 PHOSPHOLIPASE B, PLB1 PHOSPHOLIPASE B1, MEMBRANE-ASSOCIATED hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;A2-type glycerophospholipase activity#GO:0004623;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620 phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid metabolic process#GO:0006629;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cell projection membrane#GO:0031253;cluster of actin-based cell projections#GO:0098862;apical part of cell#GO:0045177;brush border membrane#GO:0031526;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;brush border#GO:0005903 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000042901.1|UniProtKB=A0A5F8GZ81 A0A5F8GZ81 TMEM107 PTHR34341:SF1 TRANSMEMBRANE PROTEIN 107 TRANSMEMBRANE PROTEIN 107 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;localization#GO:0051179;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;protein localization to cilium#GO:0061512 membrane-bounded organelle#GO:0043227;cilium#GO:0005929;ciliary transition zone#GO:0035869;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000004641.4|UniProtKB=A0A5F8G272 A0A5F8G272 KIAA0513 PTHR13663:SF2 SIMILAR TO RIKEN CDNA 6430548M08 RIKEN CDNA 6430548M08 GENE LIKE MONDO|Ensembl=ENSMODG00000001090.2|UniProtKB=A0A5F8G8E6 A0A5F8G8E6 PTHR12441:SF10 ATP SYNTHASE COUPLING FACTOR 6, MITOCHONDRIAL ATP SYNTHASE PERIPHERAL STALK SUBUNIT F6, MITOCHONDRIAL membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;proton-transporting ATP synthase complex#GO:0045259;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 primary active transporter#PC00068;ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000010717.4|UniProtKB=A0A5F8G1X9 A0A5F8G1X9 PCDHGC5 PTHR24028:SF236 CADHERIN-87A PROTOCADHERIN ALPHA-C1 cell adhesion#GO:0007155;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000016777.4|UniProtKB=A0A5F8GHD6 A0A5F8GHD6 ANTKMT PTHR13610:SF5 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN ADENINE NUCLEOTIDE TRANSLOCASE LYSINE N-METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000027855.2|UniProtKB=F7G350 F7G350 LOC103092433 PTHR24377:SF641 IP01015P-RELATED ZINC FINGER PROTEIN 354B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015458.4|UniProtKB=F6S3M2 F6S3M2 FEZF1 PTHR24390:SF70 ZINC FINGER PROTEIN FEZ FAMILY ZINC FINGER PROTEIN 1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000007742.4|UniProtKB=F7BK92 F7BK92 NOSTRIN PTHR23065:SF7 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 NOSTRIN, ISOFORM H cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000020215.4|UniProtKB=A0A5F8GWT8 A0A5F8GWT8 PTHR23320:SF128 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 4A-LIKE transporter#PC00227 MONDO|Ensembl=ENSMODG00000011076.4|UniProtKB=A0A5F8GV86 A0A5F8GV86 PTHR24051:SF10 SUSHI DOMAIN-CONTAINING PROTEIN 1 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE U extracellular matrix glycoprotein#PC00100 MONDO|Ensembl=ENSMODG00000009370.3|UniProtKB=F7CQ50 F7CQ50 PTHR24235:SF21 NEUROPEPTIDE Y RECEPTOR PROLACTIN RELEASING HORMONE RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018384.4|UniProtKB=F6QV09 F6QV09 SLC6A13 PTHR11616:SF111 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 2 amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171 metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;amino acid transport#GO:0006865 cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000009659.5|UniProtKB=F6Q8A1 F6Q8A1 PTHR23167:SF42 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED EH DOMAIN-BINDING PROTEIN 1-LIKE PROTEIN 1 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018647.4|UniProtKB=H9H763 H9H763 HES4 PTHR10985:SF136 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED C-HAIRY1A-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of neurogenesis#GO:0050767;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;anterior/posterior pattern specification#GO:0009952;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 MONDO|Ensembl=ENSMODG00000029333.2|UniProtKB=K7E233 K7E233 FAM170B PTHR33517:SF6 PROTEIN FAM170B-RELATED FAMILY WITH SEQUENCE SIMILARITY 170 MEMBER B sexual reproduction#GO:0019953;reproductive process#GO:0022414;fertilization#GO:0009566 MONDO|Ensembl=ENSMODG00000004613.4|UniProtKB=F6Y3H2 F6Y3H2 NIBAN2 PTHR14392:SF2 NIBAN FAMILY MEMBER PROTEIN NIBAN 2 MONDO|Ensembl=ENSMODG00000027530.2|UniProtKB=K7DZM7 K7DZM7 PTHR46890:SF56 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED OS06G0484800 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000047566.1|UniProtKB=A0A5F8GYW3 A0A5F8GYW3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000013112.3|UniProtKB=A0A5F8GD96 A0A5F8GD96 RARA PTHR24082:SF115 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR ALPHA sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to hormone stimulus#GO:0032870;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;hormone-mediated signaling pathway#GO:0009755;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;intracellular receptor signaling pathway#GO:0030522;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 C4 zinc finger nuclear receptor#PC00169 Vitamin D metabolism and pathway#P04396>RXR#P04602 MONDO|Ensembl=ENSMODG00000047174.1|UniProtKB=F6QLA7 F6QLA7 VN2R506 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000009093.3|UniProtKB=F7FQM3 F7FQM3 CHMP7 PTHR22761:SF21 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 7 cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;membrane assembly#GO:0071709;late endosome to vacuole transport#GO:0045324;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;nuclear envelope organization#GO:0006998;endosomal transport#GO:0016197;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;endosome transport via multivesicular body sorting pathway#GO:0032509;endomembrane system organization#GO:0010256;membrane organization#GO:0061024 cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770;plasma membrane#GO:0005886;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasmic side of membrane#GO:0098562;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;vesicle#GO:0031982;side of membrane#GO:0098552;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000040795.1|UniProtKB=A0A5F8H614 A0A5F8H614 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000015340.2|UniProtKB=F6XEP3 F6XEP3 PTHR12509:SF16 SPERMATOGENESIS-ASSOCIATED 4-RELATED SPERM FLAGELLA AND CILIA-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 biological regulation#GO:0065007;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;axoneme#GO:0005930;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000043253.1|UniProtKB=A0A5F8GQ10 A0A5F8GQ10 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000113.4|UniProtKB=F6YC15 F6YC15 CCKAR PTHR24241:SF120 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR CHOLECYSTOKININ RECEPTOR TYPE A molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;regulation of hormone secretion#GO:0046883;cell communication#GO:0007154;regulation of secretion#GO:0051046;regulation of hormone levels#GO:0010817;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of cell communication#GO:0010646;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008961.3|UniProtKB=F7G2D4 F7G2D4 BPNT2 PTHR43028:SF6 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 GOLGI-RESIDENT ADENOSINE 3',5'-BISPHOSPHATE 3'-PHOSPHATASE catalytic activity#GO:0003824;phosphatase activity#GO:0016791;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;cartilage development#GO:0051216;system development#GO:0048731;cellular process#GO:0009987;tissue development#GO:0009888;multicellular organismal process#GO:0032501;chondrocyte differentiation#GO:0002062;developmental process#GO:0032502;cellular developmental process#GO:0048869;animal organ development#GO:0048513;multicellular organism development#GO:0007275;connective tissue development#GO:0061448 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphatase#PC00181;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000038419.1|UniProtKB=A0A5F8GUH1 A0A5F8GUH1 WASHC3 PTHR13015:SF0 PROTEIN AD-016-RELATED WASH COMPLEX SUBUNIT 3 actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;transport#GO:0006810;exocytosis#GO:0006887;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;export from cell#GO:0140352;actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;secretion by cell#GO:0032940;supramolecular fiber organization#GO:0097435;localization#GO:0051179;secretion#GO:0046903 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000046944.1|UniProtKB=A0A5F8GWQ7 A0A5F8GWQ7 PTHR33426:SF54 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000001417.4|UniProtKB=F7BCX5 F7BCX5 ARHGAP11A PTHR15670:SF4 RHO GTPASE ACTIVATING PROTEIN 11A INACTIVE RHO GTPASE-ACTIVATING PROTEIN 11B-RELATED enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000015695.4|UniProtKB=A0A5F8HBB7 A0A5F8HBB7 PRRC2A PTHR14038:SF5 BAT2 HLA-B-ASSOCIATED TRANSCRIPT 2 PROTEIN PRRC2A RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000000969.3|UniProtKB=F7ESW0 F7ESW0 RPS3A PTHR11830:SF28 40S RIBOSOMAL PROTEIN S3A SMALL RIBOSOMAL SUBUNIT PROTEIN ES1 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000037566.1|UniProtKB=A0A5F8G252 A0A5F8G252 INSL3 PTHR10423:SF3 INSULIN-LIKE 3 INSULIN-LIKE 3 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;molecular function activator activity#GO:0140677 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of reproductive process#GO:2000241;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000008922.5|UniProtKB=F7BFR8 F7BFR8 SIN3A PTHR12346:SF2 SIN3B-RELATED PAIRED AMPHIPATHIC HELIX PROTEIN SIN3A transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Sin3-type complex#GO:0070822;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>Sin3A#P00771;p53 pathway#P00059>Sin3#P04622 MONDO|Ensembl=ENSMODG00000014674.4|UniProtKB=F7E7L5 F7E7L5 LOC100013399 PTHR24291:SF198 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4F11 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000010347.4|UniProtKB=F6S8D0 F6S8D0 MRPS31 PTHR13231:SF3 MITOCHONDRIAL RIBOSOMAL PROTEIN S31 SMALL RIBOSOMAL SUBUNIT PROTEIN MS31 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000041967.1|UniProtKB=F7EBH8 F7EBH8 LOC100028578 PTHR48002:SF153 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016945.4|UniProtKB=F6V6G0 F6V6G0 PTHR24256:SF521 TRYPTASE-RELATED TRYPTASE DELTA catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000014597.4|UniProtKB=A0A5F8HAQ6 A0A5F8HAQ6 ZNF462 PTHR24403:SF58 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 462 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000028085.2|UniProtKB=K7E2L0 K7E2L0 LOC100032319 PTHR13622:SF16 THIAMIN PYROPHOSPHOKINASE SI:DKEY-6N6.2 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110 transferase#PC00220;kinase#PC00137 MONDO|Ensembl=ENSMODG00000008889.3|UniProtKB=F7BRY9 F7BRY9 ACVR2B PTHR23255:SF70 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-2B catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;activin binding#GO:0048185;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;transmembrane signaling receptor activity#GO:0004888 transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cellular response to growth factor stimulus#GO:0071363;pattern specification process#GO:0007389;activin receptor signaling pathway#GO:0032924 protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;signaling receptor complex#GO:0043235;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>ActRII/IIB#P06780;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277 MONDO|Ensembl=ENSMODG00000005187.4|UniProtKB=A0A5F8H366 A0A5F8H366 SNX19 PTHR22775:SF31 SORTING NEXIN SORTING NEXIN-19 ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;small molecule binding#GO:0036094;binding#GO:0005488 intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000002922.4|UniProtKB=A0A5F8HG58 A0A5F8HG58 PTHR11258:SF16 2-5 OLIGOADENYLATE SYNTHETASE 2'-5'-OLIGOADENYLATE SYNTHASE-LIKE PROTEIN RNA binding#GO:0003723;adenylyltransferase activity#GO:0070566;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 response to virus#GO:0009615;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;antiviral innate immune response#GO:0140374;cellular response to stimulus#GO:0051716;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955;response to peptide#GO:1901652;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;negative regulation of biological process#GO:0048519;defense response to virus#GO:0051607;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cell surface receptor signaling pathway#GO:0007166;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;defense response to symbiont#GO:0140546 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;organelle lumen#GO:0043233;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;nucleotidyltransferase#PC00174 MONDO|Ensembl=ENSMODG00000036952.1|UniProtKB=A0A5F8HC00 A0A5F8HC00 APOA5 PTHR18976:SF13 APOLIPOPROTEIN APOLIPOPROTEIN A-V sterol transfer activity#GO:0120015;transporter activity#GO:0005215;enzyme activator activity#GO:0008047;phospholipid binding#GO:0005543;molecular function regulator activity#GO:0098772;cholesterol transfer activity#GO:0120020;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;binding#GO:0005488;lipid transfer activity#GO:0120013;molecular function activator activity#GO:0140677;lipid binding#GO:0008289;enzyme regulator activity#GO:0030234 primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;cholesterol efflux#GO:0033344;cellular process#GO:0009987;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;phospholipid transport#GO:0015914;steroid metabolic process#GO:0008202;lipid transport#GO:0006869;transport#GO:0006810;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;sterol metabolic process#GO:0016125;establishment of localization#GO:0051234;sterol transport#GO:0015918 high-density lipoprotein particle#GO:0034364;membrane-bounded organelle#GO:0043227;plasma lipoprotein particle#GO:0034358;lipoprotein particle#GO:1990777;extracellular protein-containing complex#GO:0140392;protein-lipid complex#GO:0032994;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;vesicle#GO:0031982;very-low-density lipoprotein particle#GO:0034361 transfer/carrier protein#PC00219;apolipoprotein#PC00052 MONDO|Ensembl=ENSMODG00000044221.1|UniProtKB=A0A5F8HGQ4 A0A5F8HGQ4 FDXACB1 PTHR11538:SF26 PHENYLALANYL-TRNA SYNTHETASE FERREDOXIN-FOLD ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 1 RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a rRNA#GO:0140102;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;translation#GO:0006412;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;rRNA processing#GO:0006364;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;rRNA modification#GO:0000154;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;methylation#GO:0032259;RNA metabolic process#GO:0016070;cellular component biogenesis#GO:0044085;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;rRNA base methylation#GO:0070475;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000018492.4|UniProtKB=F7BRM4 F7BRM4 LOC100022478 PTHR11732:SF548 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3 alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491 steroid metabolic process#GO:0008202;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000043079.1|UniProtKB=A0A5F8G9Q2 A0A5F8G9Q2 DRG2 PTHR43127:SF2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;guanyl nucleotide binding#GO:0019001 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000000873.4|UniProtKB=A0A5F8G966 A0A5F8G966 SAMD8 PTHR21290:SF69 SPHINGOMYELIN SYNTHETASE SPHINGOMYELIN SYNTHASE-RELATED PROTEIN 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;catalytic activity#GO:0003824;transferase activity#GO:0016740 ceramide metabolic process#GO:0006672;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000037918.1|UniProtKB=A0A5F8H7G0 A0A5F8H7G0 PTHR24242:SF197 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000009131.3|UniProtKB=F7EY00 F7EY00 PTHR26453:SF163 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017555.4|UniProtKB=A0A5F8HJ39 A0A5F8HJ39 QSOX2 PTHR22897:SF7 QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE SULFHYDRYL OXIDASE 2 disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 protein folding#GO:0006457;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;external encapsulating structure organization#GO:0045229;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;extracellular structure organization#GO:0043062;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;protein maturation#GO:0051604;extracellular matrix assembly#GO:0085029;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 oxidase#PC00175;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000042045.1|UniProtKB=A0A5F8G6M8 A0A5F8G6M8 PTHR28602:SF1 ENDOTHELIAL CELL-SPECIFIC CHEMOTAXIS REGULATOR ENDOTHELIAL CELL-SPECIFIC CHEMOTAXIS REGULATOR negative regulation of multicellular organismal process#GO:0051241;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of macromolecule metabolic process#GO:0060255;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of angiogenesis#GO:0045765;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of vasculature development#GO:1901342;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;negative regulation of angiogenesis#GO:0016525;positive regulation of catabolic process#GO:0009896;regulation of anatomical structure morphogenesis#GO:0022603;regulation of catabolic process#GO:0009894 cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000020704.4|UniProtKB=K7E2Q4 K7E2Q4 POLR2B PTHR20856:SF7 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000015071.2|UniProtKB=F7FH93 F7FH93 OPN1SW PTHR24240:SF16 OPSIN SHORT-WAVE-SENSITIVE OPSIN 1 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;biological regulation#GO:0065007;detection of stimulus#GO:0051606;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;signaling#GO:0023052;cellular response to radiation#GO:0071478;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cilium#GO:0005929;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;photoreceptor outer segment#GO:0001750;organelle#GO:0043226 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000020295.3|UniProtKB=A0A5F8H5L4 A0A5F8H5L4 VN2R643 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003453.3|UniProtKB=F7DWS0 F7DWS0 EXTL2 PTHR11062:SF117 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-LIKE 2 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000004242.3|UniProtKB=F6UBE9 F6UBE9 PGAM1 PTHR11931:SF15 PHOSPHOGLYCERATE MUTASE PHOSPHOGLYCERATE MUTASE 1 catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;intramolecular phosphotransferase activity#GO:0016868;isomerase activity#GO:0016853;phosphoglycerate mutase activity#GO:0004619 oxoacid metabolic process#GO:0043436;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;carbohydrate metabolic process#GO:0005975;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleotide catabolic process#GO:0009166;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;nucleobase-containing compound metabolic process#GO:0006139 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 mutase#PC00160;isomerase#PC00135 Glycolysis#P00024>Phosphoglyceromutase#P00680 MONDO|Ensembl=ENSMODG00000014267.2|UniProtKB=F6XIP7 F6XIP7 CMTR2 PTHR16121:SF2 CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1-RELATED CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000016648.4|UniProtKB=F7GGT5 F7GGT5 RBM17 PTHR13288:SF9 SPLICING FACTOR 45 SPF45 SPLICING FACTOR 45 RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000040405.1|UniProtKB=F7EY70 F7EY70 LOC100014102 PTHR26452:SF204 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000019541.3|UniProtKB=F6UUG6 F6UUG6 PSMF1 PTHR13266:SF1 PROTEASOME INHIBITOR PROTEASOME INHIBITOR PI31 SUBUNIT negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000028870.2|UniProtKB=K7E2K6 K7E2K6 PTHR45710:SF20 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 C-TYPE LECTIN DOMAIN FAMILY 2, MEMBER M receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;T cell activation#GO:0042110;leukocyte activation#GO:0045321;cell communication#GO:0007154;cell activation#GO:0001775;regulation of immune response#GO:0050776;immune system process#GO:0002376;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;lymphocyte activation#GO:0046649;antigen receptor-mediated signaling pathway#GO:0050851;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000009946.4|UniProtKB=F6QMW6 F6QMW6 PTHR44427:SF1 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CELL ADHESION MOLECULE CEACAM1 protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000021457.4|UniProtKB=F7GLP9 F7GLP9 L3MBTL4 PTHR12247:SF78 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 4 protein binding#GO:0005515;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000004365.3|UniProtKB=F6W9U0 F6W9U0 SLC6A14 PTHR11616:SF286 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT NEUTRAL AND BASIC AMINO ACID TRANSPORTER B(0+) quaternary ammonium group transmembrane transporter activity#GO:0015651;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid transmembrane transporter activity#GO:0015171;branched-chain amino acid transmembrane transporter activity#GO:0015658;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873 glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;amino acid transport#GO:0006865;import into cell#GO:0098657;establishment of localization#GO:0051234;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000025437.2|UniProtKB=F7BVK1 F7BVK1 LOC100022185 PTHR10880:SF48 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000019386.3|UniProtKB=A0A5F8H1C8 A0A5F8H1C8 EFL1 PTHR42908:SF3 TRANSLATION ELONGATION FACTOR-RELATED ELONGATION FACTOR-LIKE GTPASE 1 ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;hydrolase activity#GO:0016787;ribonucleoprotein complex binding#GO:0043021;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 translation#GO:0006412;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;ribosome biogenesis#GO:0042254;protein metabolic process#GO:0019538;membraneless organelle assembly#GO:0140694;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;translational elongation#GO:0006414;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467 ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation elongation factor#PC00222 MONDO|Ensembl=ENSMODG00000050691.1|UniProtKB=A0A5F8GQ18 A0A5F8GQ18 PTHR47958:SF90 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX5-RELATED catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000003288.3|UniProtKB=F7EG80 F7EG80 PTHR23226:SF127 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 24 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000047829.1|UniProtKB=A0A5F8G3Q8 A0A5F8G3Q8 LOC100012857 PTHR12411:SF902 CYSTEINE PROTEASE FAMILY C1-RELATED PROCATHEPSIN L endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000000670.4|UniProtKB=F6X236 F6X236 TMEM184C PTHR23423:SF10 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184C transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000008841.4|UniProtKB=F7CUS8 F7CUS8 UBE2F PTHR24068:SF129 UBIQUITIN-CONJUGATING ENZYME E2 NEDD8-CONJUGATING ENZYME UBE2F ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000008499.4|UniProtKB=F7FTR2 F7FTR2 ABI1 PTHR10460:SF2 ABL INTERACTOR FAMILY MEMBER ABL INTERACTOR 1 signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular developmental process#GO:0048869;neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;developmental process#GO:0032502;cell migration#GO:0016477;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 actin cytoskeleton#GO:0015629;cell leading edge#GO:0031252;actin-based cell projection#GO:0098858;lamellipodium#GO:0030027;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000433.4|UniProtKB=F6UT87 F6UT87 MARCO PTHR24023:SF1083 COLLAGEN ALPHA MACROPHAGE RECEPTOR MARCO extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000021347.3|UniProtKB=H9H7Y9 H9H7Y9 MARCHF9 PTHR46053:SF4 E3 UBIQUITIN-PROTEIN LIGASE MARCH4-LIKE E3 UBIQUITIN-PROTEIN LIGASE MARCHF9 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;Golgi stack#GO:0005795;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000018963.4|UniProtKB=F7G0D4 F7G0D4 XPO5 PTHR11223:SF3 EXPORTIN 1/5 EXPORTIN-5 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 MONDO|Ensembl=ENSMODG00000016936.2|UniProtKB=A0A5F8GMA0 A0A5F8GMA0 MEIG1 PTHR17008:SF1 MEIOSIS-EXPRESSED GENE 1 PROTEIN MEIOSIS EXPRESSED GENE 1 PROTEIN HOMOLOG male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;spermatogenesis#GO:0007283;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;microtubule-based process#GO:0007017;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000006040.4|UniProtKB=F6ZU67 F6ZU67 PPL PTHR23169:SF10 ENVOPLAKIN PERIPLAKIN cellular component organization or biogenesis#GO:0071840;wound healing#GO:0042060;intermediate filament-based process#GO:0045103;response to stimulus#GO:0050896;intermediate filament cytoskeleton organization#GO:0045104;cytoskeleton organization#GO:0007010;response to wounding#GO:0009611;response to stress#GO:0006950;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane#GO:0016020 intermediate filament binding protein#PC00130;intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000005734.5|UniProtKB=F6QED6 F6QED6 CARMIL2 PTHR24112:SF32 LEUCINE-RICH REPEAT, ISOFORM F-RELATED CAPPING PROTEIN, ARP2_3 AND MYOSIN-I LINKER PROTEIN 2 regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;cell migration#GO:0016477;regulation of cellular process#GO:0050794;cell motility#GO:0048870;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of organelle organization#GO:0033043 cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000019322.3|UniProtKB=A0A5F8H7Q1 A0A5F8H7Q1 PIPOX PTHR10961:SF46 PEROXISOMAL SARCOSINE OXIDASE PEROXISOMAL SARCOSINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidase#PC00175;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000005073.4|UniProtKB=F7AS43 F7AS43 RNF32 PTHR14991:SF0 RING FINGER PROTEIN 32 RING FINGER PROTEIN 32 MONDO|Ensembl=ENSMODG00000021021.4|UniProtKB=A0A5F8GZA1 A0A5F8GZA1 UBASH3A PTHR16469:SF7 UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING PROTEIN A regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000003214.4|UniProtKB=F6TZ81 F6TZ81 RAB3A PTHR47980:SF9 LD44762P RAS-RELATED PROTEIN RAB-3A myosin binding#GO:0017022;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular localization#GO:0051641;axonogenesis#GO:0007409;neuron development#GO:0048666;secretion by cell#GO:0032940;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;fertilization#GO:0009566;signaling#GO:0023052;export from cell#GO:0140352;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;acrosome reaction#GO:0007340;regulation of biological process#GO:0050789;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;exocytosis#GO:0006887;cell projection morphogenesis#GO:0048858;regulated exocytosis#GO:0045055;plasma membrane bounded cell projection morphogenesis#GO:0120039;acrosomal vesicle exocytosis#GO:0060478;neuron differentiation#GO:0030182;vesicle-mediated transport#GO:0016192;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;single fertilization#GO:0007338;neuron projection development#GO:0031175;cellular process#GO:0009987;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;secretion#GO:0046903;anatomical structure development#GO:0048856;localization#GO:0051179;cell communication#GO:0007154;system development#GO:0048731;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;sexual reproduction#GO:0019953;anterograde trans-synaptic signaling#GO:0098916;reproductive process#GO:0022414;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;neurogenesis#GO:0022008;calcium-ion regulated exocytosis#GO:0017156;neuron projection morphogenesis#GO:0048812;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;developmental process#GO:0032502;multicellular organismal process#GO:0032501;neurotransmitter secretion#GO:0007269;plasma membrane bounded cell projection organization#GO:0120036;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;axon development#GO:0061564 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axon#GO:0030424;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;organelle membrane#GO:0031090;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;exocytic vesicle#GO:0070382;endosome#GO:0005768;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;intracellular vesicle#GO:0097708;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;neuron projection#GO:0043005;presynapse#GO:0098793 Synaptic vesicle trafficking#P05734>Rab3A#P05780 MONDO|Ensembl=ENSMODG00000005524.4|UniProtKB=F7FUT9 F7FUT9 ARHGAP45 PTHR15228:SF18 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 45 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;membrane#GO:0016020 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000005879.4|UniProtKB=F6SN91 F6SN91 LRIT3 PTHR45842:SF8 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEAT, IMMUNOGLOBULIN-LIKE DOMAIN AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 3 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000001600.3|UniProtKB=F7BB14 F7BB14 ANKMY2 PTHR24150:SF8 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000022571.2|UniProtKB=H9H853 H9H853 LOC100030085 PTHR26454:SF0 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021258.4|UniProtKB=F6TIA5 F6TIA5 HLTF PTHR45626:SF17 TRANSCRIPTION TERMINATION FACTOR 2-RELATED DNA-DEPENDENT ATPASE_E3 UBIQUITIN-PROTEIN LIGASE HLTF ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000015566.4|UniProtKB=F6QIP1 F6QIP1 ULK1 PTHR24348:SF19 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE ULK1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 plasma membrane bounded cell projection morphogenesis#GO:0120039;metabolic process#GO:0008152;regulation of axonogenesis#GO:0050770;cell projection morphogenesis#GO:0048858;cell growth#GO:0016049;autophagy#GO:0006914;response to stress#GO:0006950;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;regulation of cell growth#GO:0001558;generation of neurons#GO:0048699;regulation of cell size#GO:0008361;developmental growth involved in morphogenesis#GO:0060560;regulation of multicellular organismal development#GO:2000026;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;cell differentiation#GO:0030154;cell projection organization#GO:0030030;developmental process#GO:0032502;autophagy of mitochondrion#GO:0000422;cellular developmental process#GO:0048869;reticulophagy#GO:0061709;axon development#GO:0061564;response to nutrient levels#GO:0031667;macroautophagy#GO:0016236;negative regulation of cell growth#GO:0030308;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;vacuole organization#GO:0007033;system development#GO:0048731;regulation of nervous system development#GO:0051960;regulation of growth#GO:0040008;negative regulation of cellular component organization#GO:0051129;response to starvation#GO:0042594;regulation of developmental process#GO:0050793;catabolic process#GO:0009056;growth#GO:0040007;neuron differentiation#GO:0030182;regulation of anatomical structure size#GO:0090066;autophagosome assembly#GO:0000045;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;autophagosome organization#GO:1905037;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;axon extension#GO:0048675;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron projection extension#GO:1990138;process utilizing autophagic mechanism#GO:0061919;neuron development#GO:0048666;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;cell development#GO:0048468;cell morphogenesis#GO:0000902;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;neuron projection morphogenesis#GO:0048812;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of catabolic process#GO:0009894;neurogenesis#GO:0022008;developmental growth#GO:0048589;regulation of plasma membrane bounded cell projection organization#GO:0120035;mitophagy#GO:0000423;regulation of cell development#GO:0060284;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;regulation of neurogenesis#GO:0050767;negative regulation of multicellular organismal process#GO:0051241;developmental cell growth#GO:0048588;piecemeal microautophagy of the nucleus#GO:0034727;regulation of cellular process#GO:0050794 membrane#GO:0016020;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;autophagosome#GO:0005776;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000027491.2|UniProtKB=K7DZU2 K7DZU2 LOC103096087 PTHR12200:SF25 INTERFERON-INDUCIBLE PROTEIN AIM2 FAMILY MEMBER PYRIN AND HIN DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;response to peptide#GO:1901652;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;positive regulation of response to external stimulus#GO:0032103;positive regulation of response to biotic stimulus#GO:0002833;activation of innate immune response#GO:0002218;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytosol#GO:0005829 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000049692.1|UniProtKB=A0A5F8HCS3 A0A5F8HCS3 NOVA1 PTHR10288:SF229 KH DOMAIN CONTAINING RNA BINDING PROTEIN RNA-BINDING PROTEIN NOVA-1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;nervous system development#GO:0007399;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;multicellular organism development#GO:0007275;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;animal gross anatomical part developmental process#GO:0160108;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions#GO:0000375;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;anatomical structure development#GO:0048856 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000005355.2|UniProtKB=F6YLH8 F6YLH8 CRELD1 PTHR24034:SF114 EGF-LIKE DOMAIN-CONTAINING PROTEIN PROTEIN DISULFIDE ISOMERASE CRELD1 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000009103.4|UniProtKB=F7FCB1 F7FCB1 VSTM2A PTHR12207:SF23 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2A cellular anatomical structure#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000028645.2|UniProtKB=K7E3Y7 K7E3Y7 LOC100619470 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005085.5|UniProtKB=F7A3V4 F7A3V4 BRPF1 PTHR13793:SF85 PHD FINGER PROTEINS PEREGRIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000016051.3|UniProtKB=F7GIZ7 F7GIZ7 HSPG2 PTHR10574:SF444 NETRIN/LAMININ-RELATED BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN tissue development#GO:0009888;anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000002986.4|UniProtKB=F6Q4U4 F6Q4U4 EHBP1 PTHR23167:SF43 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED EH DOMAIN-BINDING PROTEIN 1 organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000011737.4|UniProtKB=F6X5V9 F6X5V9 NRG2 PTHR11100:SF20 HEREGULIN-NEUREGULIN FAMILY MEMBER PRO-NEUREGULIN-2, MEMBRANE-BOUND ISOFORM signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 animal organ development#GO:0048513;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signal transduction#GO:0007165;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;intracellular signal transduction#GO:0035556;animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 EGF receptor signaling pathway#P00018>EGF#P00549 MONDO|Ensembl=ENSMODG00000002193.4|UniProtKB=A0A5F8GRP2 A0A5F8GRP2 MAPK8 PTHR24055:SF222 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 8 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of programmed cell death#GO:0043067;response to abiotic stimulus#GO:0009628;intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;JNK cascade#GO:0007254;response to mechanical stimulus#GO:0009612;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to external stimulus#GO:0009605;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Angiogenesis#P00005>JNK1#P00221;Ras Pathway#P04393>JNK#P04572;PDGF signaling pathway#P00047>ERK#P01143;B cell activation#P00010>Jnk#P00402;CCKR signaling map#P06959>MAPK8-10#P07090;Apoptosis signaling pathway#P00006>JNK#P00274;Gonadotropin-releasing hormone receptor pathway#P06664>JNK1/2#P06847;Oxidative stress response#P00046>JNK1/2#P01129;Parkinson disease#P00049>SAPK#P01219;Toll receptor signaling pathway#P00054>JNK#P01375;TGF-beta signaling pathway#P00052>JNK#P01284;T cell activation#P00053>Jnk#P01336;FGF signaling pathway#P00021>JNK1-3#P00628;Integrin signalling pathway#P00034>Jnk#P00951;FAS signaling pathway#P00020>JNK#P00615;EGF receptor signaling pathway#P00018>JNK1-3#P00545 MONDO|Ensembl=ENSMODG00000040008.1|UniProtKB=A0A5F8HKW0 A0A5F8HKW0 PTHR11471:SF24 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15 cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of apoptotic process#GO:0043065;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of extrinsic apoptotic signaling pathway#GO:2001236;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of apoptotic signaling pathway#GO:2001233 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000018274.4|UniProtKB=F6Q6L0 F6Q6L0 GOLGB1 PTHR18887:SF2 GOLGI-ASSOCIATED PROTEIN GCP360-RELATED GOLGIN SUBFAMILY B MEMBER 1 intracellular anatomical structure#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 MONDO|Ensembl=ENSMODG00000038571.1|UniProtKB=A0A5F8GJT7 A0A5F8GJT7 PTHR24089:SF196 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL ADENYL NUCLEOTIDE ANTIPORTER SLC25A23 purine nucleotide transmembrane transporter activity#GO:0015216;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;phosphate transmembrane transporter activity#GO:0005315 cellular process#GO:0009987;mitochondrial calcium ion transmembrane transport#GO:0006851;nitrogen compound transport#GO:0071705;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;carbohydrate derivative transport#GO:1901264;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 MONDO|Ensembl=ENSMODG00000005701.3|UniProtKB=F6UJW3 F6UJW3 CDC37 PTHR12800:SF3 CDC37-RELATED HSP90 CO-CHAPERONE CDC37 protein binding#GO:0005515;binding#GO:0005488;heat shock protein binding#GO:0031072 metabolic process#GO:0008152;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;regulation of innate immune response#GO:0045088;regulation of cytokine-mediated signaling pathway#GO:0001959;protein stabilization#GO:0050821;regulation of response to cytokine stimulus#GO:0060759;regulation of protein stability#GO:0031647;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;regulation of response to external stimulus#GO:0032101;protein maturation#GO:0051604;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;regulation of defense response#GO:0031347;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to biotic stimulus#GO:0002831;protein folding#GO:0006457;regulation of cell communication#GO:0010646 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein folding chaperone complex#GO:0101031 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000006160.3|UniProtKB=F7BS73 F7BS73 VAMP7 PTHR21136:SF179 SNARE PROTEINS VESICLE-ASSOCIATED MEMBRANE PROTEIN 7 protein binding#GO:0005515;SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;binding#GO:0005488 Golgi to plasma membrane transport#GO:0006893;catabolic process#GO:0009056;microtubule-based movement#GO:0007018;vesicle fusion#GO:0006906;protein localization to plasma membrane#GO:0072659;Golgi organization#GO:0007030;localization#GO:0051179;secretion#GO:0046903;endosome to lysosome transport#GO:0008333;organelle localization#GO:0051640;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;cytoskeleton-dependent intracellular transport#GO:0030705;membrane organization#GO:0061024;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;vesicle localization#GO:0051648;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vesicle cytoskeletal trafficking#GO:0099518;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;phagocytosis#GO:0006909;vacuolar transport#GO:0007034;transport#GO:0006810;endocytosis#GO:0006897;establishment of organelle localization#GO:0051656;export from cell#GO:0140352;Golgi to plasma membrane protein transport#GO:0043001;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;secretion by cell#GO:0032940;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;lysosomal transport#GO:0007041;microtubule-based transport#GO:0099111;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of vesicle localization#GO:0051650;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle transport along microtubule#GO:0072384;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;autophagy#GO:0006914;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;import into cell#GO:0098657;exocytosis#GO:0006887;vesicle organization#GO:0016050;microtubule-based process#GO:0007017;metabolic process#GO:0008152;protein localization to cell periphery#GO:1990778;membrane invagination#GO:0010324;Golgi vesicle transport#GO:0048193 intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150;SNARE protein#PC00034 MONDO|Ensembl=ENSMODG00000014756.4|UniProtKB=A0A5F8GTH7 A0A5F8GTH7 ELF1 PTHR11849:SF156 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 MONDO|Ensembl=ENSMODG00000017327.3|UniProtKB=F6WWE5 F6WWE5 DENND4B PTHR12296:SF18 DENN DOMAIN-CONTAINING PROTEIN 4 DENN DOMAIN-CONTAINING PROTEIN 4B enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000005899.3|UniProtKB=F6S4X6 F6S4X6 GABRA3 PTHR18945:SF216 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-3 channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;neurotransmitter receptor activity#GO:0030594 establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;chloride transport#GO:0006821;cellular component assembly#GO:0022607;monoatomic anion transmembrane transport#GO:0098656;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;cellular process#GO:0009987;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;animal gross anatomical part developmental process#GO:0160108;synapse assembly#GO:0007416;signaling#GO:0023052;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 postsynapse#GO:0098794;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;leading edge membrane#GO:0031256;dendrite#GO:0030425;cell projection membrane#GO:0031253;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235;cell junction#GO:0030054 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000025259.3|UniProtKB=F7BDA0 F7BDA0 INSYN1 PTHR15917:SF3 FAMILY NOT NAMED INHIBITORY SYNAPTIC FACTOR 1 trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;regulation of biological quality#GO:0065008;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of postsynaptic membrane potential#GO:0060078;cellular response to stimulus#GO:0051716;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;chemical synaptic transmission, postsynaptic#GO:0099565;cell surface receptor signaling pathway#GO:0007166;regulation of membrane potential#GO:0042391;system process#GO:0003008;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 organelle#GO:0043226;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;cell junction#GO:0030054;postsynaptic density#GO:0014069 MONDO|Ensembl=ENSMODG00000009279.4|UniProtKB=F7CR61 F7CR61 CCDC157 PTHR43696:SF9 COILED-COIL DOMAIN-CONTAINING PROTEIN 157 COILED-COIL DOMAIN-CONTAINING PROTEIN 157 MONDO|Ensembl=ENSMODG00000024147.2|UniProtKB=F6U499 F6U499 FIGNL1 PTHR23074:SF75 AAA DOMAIN-CONTAINING FIDGETIN-LIKE PROTEIN 1 ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity, acting on a protein#GO:0140096;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000019145.4|UniProtKB=F7EC88 F7EC88 S1PR4 PTHR22750:SF13 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000011427.3|UniProtKB=F6RKG5 F6RKG5 PTHR12348:SF29 TSC22 TSC22 DOMAIN FAMILY MEMBER 3 MONDO|Ensembl=ENSMODG00000004597.4|UniProtKB=F6QIM4 F6QIM4 RRN3 PTHR12790:SF0 TRANSCRIPTION INITIATION FACTOR IA RRN3 RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED transcription by RNA polymerase I#GO:0006360;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;transcription initiation at RNA polymerase I promoter#GO:0006361;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 MONDO|Ensembl=ENSMODG00000011845.4|UniProtKB=F7GLL1 F7GLL1 ENTREP2 PTHR17615:SF6 PROTEIN FAM189A PROTEIN ENTREP2 MONDO|Ensembl=ENSMODG00000014724.4|UniProtKB=F6ZD47 F6ZD47 GUCY1A2 PTHR45655:SF7 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT ALPHA-2 lyase activity#GO:0016829;guanylate cyclase activity#GO:0004383;catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849 response to abiotic stimulus#GO:0009628;response to oxygen levels#GO:0070482;response to stimulus#GO:0050896 cytosol#GO:0005829;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 guanylate cyclase#PC00114;cyclase#PC00079 Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 MONDO|Ensembl=ENSMODG00000018553.2|UniProtKB=F7G2J7 F7G2J7 A4GNT PTHR12042:SF16 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycosphingolipid biosynthetic process#GO:0006688;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;glycoprotein metabolic process#GO:0009100;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000008963.5|UniProtKB=F7G2C4 F7G2C4 NUP133 PTHR13405:SF11 NUCLEAR PORE COMPLEX PROTEIN NUP133 NUCLEAR PORE COMPLEX PROTEIN NUP133 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleobase-containing compound transport#GO:0015931;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;RNA transport#GO:0050658;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;chromosome organization#GO:0051276;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;protein import into nucleus#GO:0006606;protein transport#GO:0015031;cellular component organization#GO:0016043;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nuclear pore outer ring#GO:0031080;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000028733.1|UniProtKB=K7E0D0 K7E0D0 LOC103104695 PTHR10424:SF74 VIRAL ENVELOPE PROTEIN ENDOGENOUS RETROVIRUS GROUP V MEMBER 2 ENV POLYPROTEIN myoblast fusion#GO:0007520;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;cell differentiation#GO:0030154;muscle structure development#GO:0061061;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;syncytium formation by cell-cell fusion#GO:0000768;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;striated muscle cell differentiation#GO:0051146 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000014707.4|UniProtKB=A0A5F8GH40 A0A5F8GH40 JAG2 PTHR24044:SF421 NOTCH LIGAND FAMILY MEMBER PROTEIN JAGGED-2 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Next#P01103;Angiogenesis#P00005>Delta/Serrate#P00226;Notch signaling pathway#P00045>Serrate#P01104 MONDO|Ensembl=ENSMODG00000003270.4|UniProtKB=F6SJ79 F6SJ79 NANS PTHR42966:SF1 N-ACETYLNEURAMINATE SYNTHASE N-ACETYLNEURAMINATE-9-PHOSPHATE SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000023966.3|UniProtKB=F7F6X0 F7F6X0 LACTBL1 PTHR22935:SF95 PENICILLIN-BINDING PROTEIN BETA-LACTAMASE-LIKE PROTEIN 1 MONDO|Ensembl=ENSMODG00000008621.4|UniProtKB=A0A5F8GUT6 A0A5F8GUT6 SUN1 PTHR12911:SF23 SAD1/UNC-84-LIKE PROTEIN-RELATED SUN DOMAIN-CONTAINING PROTEIN 1 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000017556.4|UniProtKB=F6SBZ0 F6SBZ0 PTHR11477:SF18 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN SPOC DOMAIN-CONTAINING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulatory ncRNA-mediated heterochromatin formation#GO:0031048;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;constitutive heterochromatin formation#GO:0140719;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000051245.1|UniProtKB=A0A5F8G6A8 A0A5F8G6A8 PTHR31283:SF5 EKC/KEOPS COMPLEX SUBUNIT PCC1 FAMILY MEMBER L ANTIGEN FAMILY MEMBER 3 protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000051195.1|UniProtKB=A0A5F8GJG7 A0A5F8GJG7 PTHR11703:SF0 DEOXYHYPUSINE SYNTHASE DEOXYHYPUSINE SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 biogenic amine metabolic process#GO:0006576;metabolic process#GO:0008152;amine metabolic process#GO:0009308;polyamine metabolic process#GO:0006595;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000007866.2|UniProtKB=A0A5F8GEA9 A0A5F8GEA9 PTHR48002:SF88 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008968.4|UniProtKB=F7G210 F7G210 LANCL2 PTHR12736:SF11 LANC-LIKE PROTEIN LANC-LIKE PROTEIN 2 regulation of cellular response to alcohol#GO:1905957;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of response to alcohol#GO:1901419;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of abscisic acid-activated signaling pathway#GO:0009787 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000011919.3|UniProtKB=F6XXT8 F6XXT8 UBE2Q2 PTHR24068:SF456 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 Q2 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000038031.1|UniProtKB=A0A5F8H365 A0A5F8H365 PTHR10271:SF4 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 2 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;immune system process#GO:0002376;response to peptide#GO:1901652;response to virus#GO:0009615;antiviral innate immune response#GO:0140374;cellular response to cytokine stimulus#GO:0071345;defense response to virus#GO:0051607;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000016406.4|UniProtKB=F7E8P4 F7E8P4 DNASE1 PTHR11371:SF27 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE-1 catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;DNA catabolic process#GO:0006308;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound catabolic process#GO:0034655 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 endodeoxyribonuclease#PC00093 MONDO|Ensembl=ENSMODG00000042191.1|UniProtKB=A0A5F8GQ16 A0A5F8GQ16 VN2R550 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005387.4|UniProtKB=F7GGE6 F7GGE6 LOC100031667 PTHR24225:SF0 CHEMOTACTIC RECEPTOR N-FORMYL PEPTIDE RECEPTOR 2 immune receptor activity#GO:0140375;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of immune response#GO:0050776;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;immune response-activating signaling pathway#GO:0002757 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000038106.1|UniProtKB=A0A5F8G3G5 A0A5F8G3G5 PTHR18939:SF4 RIBOSOME BINDING PROTEIN-1 RIBOSOME-BINDING PROTEIN 1 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000016915.5|UniProtKB=F6VNA2 F6VNA2 EPM2A PTHR46864:SF1 LAFORIN LAFORIN phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000049975.1|UniProtKB=A0A5F8GWG4 A0A5F8GWG4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000018950.4|UniProtKB=F7GAQ8 F7GAQ8 VEGFA PTHR12025:SF5 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR A, LONG FORM signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 blood vessel morphogenesis#GO:0048514;response to abiotic stimulus#GO:0009628;response to endogenous stimulus#GO:0009719;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;vascular endothelial growth factor receptor signaling pathway#GO:0048010;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;sprouting angiogenesis#GO:0002040;angiogenesis#GO:0001525;cellular response to growth factor stimulus#GO:0071363;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of response to external stimulus#GO:0032101;cell surface receptor signaling pathway#GO:0007166;positive regulation of response to external stimulus#GO:0032103;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of leukocyte migration#GO:0002685;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;positive regulation of chemotaxis#GO:0050921;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;tube development#GO:0035295;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cell migration#GO:0030334;response to hypoxia#GO:0001666;positive regulation of locomotion#GO:0040017 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 VEGF signaling pathway#P00056>VEGF#P01406;Angiogenesis#P00005>VEGF#P00241 MONDO|Ensembl=ENSMODG00000007864.5|UniProtKB=F7EBF5 F7EBF5 TPRA1 PTHR15876:SF8 TRANSMEMBRANE PROTEIN ADIPOCYTE-ASSOCIATED 1 TRANSMEMBRANE PROTEIN ADIPOCYTE-ASSOCIATED 1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000025660.3|UniProtKB=F6XDL1 F6XDL1 LOC100017089 PTHR47966:SF24 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED RENIN catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 circulatory system process#GO:0003013;proteolysis#GO:0006508;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;system process#GO:0003008;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;peptide hormone processing#GO:0016486;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;gene expression#GO:0010467;hormone metabolic process#GO:0042445;blood circulation#GO:0008015;biological regulation#GO:0065007;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;aspartic protease#PC00053 MONDO|Ensembl=ENSMODG00000002001.3|UniProtKB=H9H5Z3 H9H5Z3 PA2G4 PTHR10804:SF11 PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P PROLIFERATION-ASSOCIATED PROTEIN 2G4 protease#PC00190 MONDO|Ensembl=ENSMODG00000005923.3|UniProtKB=F6WX53 F6WX53 LOC100012002 PTHR11214:SF151 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000006669.4|UniProtKB=F7FT98 F7FT98 PDILT PTHR18929:SF58 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE-LIKE PROTEIN OF THE TESTIS intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 gene expression#GO:0010467;protein maturation#GO:0051604;response to stimulus#GO:0050896;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000000300.3|UniProtKB=F6WAG4 F6WAG4 RPUSD2 PTHR21600:SF40 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE RPUSD2 catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000007283.4|UniProtKB=F6SHK6 F6SHK6 KIF20B PTHR24115:SF534 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF20B isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000010449.4|UniProtKB=F6YSA2 F6YSA2 BCCIP PTHR13261:SF0 BRCA2 AND CDKN1A INTERACTING PROTEIN BRCA2 AND CDKN1A-INTERACTING PROTEIN enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;mitotic spindle organization#GO:0007052;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;microtubule-based process#GO:0007017;regulation of protein modification process#GO:0031399;mitotic cell cycle process#GO:1903047;microtubule anchoring#GO:0034453;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;mitotic spindle pole#GO:0097431;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000011212.3|UniProtKB=F6SQ86 F6SQ86 PTHR26450:SF121 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52A4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015362.4|UniProtKB=F6WHP0 F6WHP0 KSR2 PTHR23257:SF775 SERINE-THREONINE PROTEIN KINASE KINASE SUPPRESSOR OF RAS 2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Ras protein signal transduction#GO:0007265;calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000048599.1|UniProtKB=K7E621 K7E621 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007548.3|UniProtKB=F7GAL2 F7GAL2 HMX2 PTHR46110:SF4 HOMEOBOX PROTEIN HMX HOMEOBOX PROTEIN HMX2 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000008853.2|UniProtKB=F7CUK8 F7CUK8 PTHR26450:SF179 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008267.4|UniProtKB=F6Z852 F6Z852 NR2C1 PTHR24083:SF49 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP C MEMBER 1 sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000019600.4|UniProtKB=F6Y829 F6Y829 PAPPA PTHR46130:SF2 LAMGL DOMAIN-CONTAINING PROTEIN PAPPALYSIN-1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000050934.1|UniProtKB=A0A5F8GMX7 A0A5F8GMX7 PIN4 PTHR45995:SF1 FAMILY NOT NAMED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 4 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000005107.4|UniProtKB=F6YQE3 F6YQE3 LOC103096413 PTHR11412:SF111 MACROGLOBULIN / COMPLEMENT VENOM FACTOR receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677 regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of immune response#GO:0050776;immune system process#GO:0002376;immune response#GO:0006955;complement activation#GO:0006956;activation of immune response#GO:0002253;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological regulation#GO:0065007;defense response to other organism#GO:0098542;positive regulation of response to stimulus#GO:0048584;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;humoral immune response#GO:0006959;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087 extracellular region#GO:0005576;catalytic complex#GO:1902494;extracellular protein-containing complex#GO:0140392;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000024750.1|UniProtKB=F7GKI6 F7GKI6 AGTR1 PTHR24228:SF11 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR TYPE-1 ANGIOTENSIN II RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 system process#GO:0003008;defense response#GO:0006952;developmental process#GO:0032502;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;regulation of blood pressure#GO:0008217;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;response to nitrogen compound#GO:1901698;circulatory system process#GO:0003013;inflammatory response#GO:0006954;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;animal organ development#GO:0048513;response to chemical#GO:0042221;renal system development#GO:0072001;kidney development#GO:0001822;response to hormone#GO:0009725;response to stress#GO:0006950;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of biological quality#GO:0065008;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;response to oxygen-containing compound#GO:1901700;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>AT1-R#P05924 MONDO|Ensembl=ENSMODG00000046303.1|UniProtKB=F6ZCD0 F6ZCD0 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000045082.1|UniProtKB=A0A5F8GFV2 A0A5F8GFV2 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010207.3|UniProtKB=F6SAW9 F6SAW9 EEF1AKMT2 PTHR12843:SF5 PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10 EEF1A LYSINE METHYLTRANSFERASE 2 protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000000977.4|UniProtKB=F7F5A9 F7F5A9 EPN2 PTHR12276:SF50 EPSIN/ENT-RELATED EPSIN-2 protein binding#GO:0005515;lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;clathrin binding#GO:0030276 cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;transport#GO:0006810;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated vesicle#GO:0030136;clathrin vesicle coat#GO:0030125;cytoplasm#GO:0005737;vesicle coat#GO:0030120;plasma membrane#GO:0005886;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000040932.1|UniProtKB=A0A5F8HF64 A0A5F8HF64 PTHR41694:SF8 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 11 POL PROTEIN-LIKE binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016312.4|UniProtKB=F7A615 F7A615 PEDS1 PTHR48230:SF1 FAMILY NOT NAMED LIPID DESATURASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000017293.5|UniProtKB=A0A5F8GMV1 A0A5F8GMV1 RUFY2 PTHR45956:SF3 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000029358.2|UniProtKB=K7DZ20 K7DZ20 PTHR24023:SF1038 COLLAGEN ALPHA COLLAGEN TYPE XV ALPHA 1 CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000023643.3|UniProtKB=F6UMW3 F6UMW3 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000049333.1|UniProtKB=A0A5F8H0A5 A0A5F8H0A5 KCTD14 PTHR14499:SF3 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD14 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000041496.1|UniProtKB=H9H6K0 H9H6K0 PTHR24399:SF77 ZINC FINGER AND BTB DOMAIN-CONTAINING ZFP14 ZINC FINGER PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cytokine production#GO:0001817;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020318.4|UniProtKB=F7G7H8 F7G7H8 PTHR23036:SF95 CYTOKINE RECEPTOR ONCOSTATIN-M-SPECIFIC RECEPTOR SUBUNIT BETA transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375 response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011350.1|UniProtKB=F6W2N8 F6W2N8 PRL PTHR11417:SF5 SOMATOTROPIN,PROLACTIN PROLACTIN protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to nutrient levels#GO:0031667;positive regulation of cellular process#GO:0048522;regulation of secretion#GO:0051046;cell communication#GO:0007154;anatomical structure development#GO:0048856;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of receptor signaling pathway via STAT#GO:1904892;reproductive process#GO:0022414;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;animal organ development#GO:0048513;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of transport#GO:0051050;cellular process#GO:0009987;positive regulation of signaling#GO:0023056;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;signaling#GO:0023052;regulation of biological process#GO:0050789;multi-multicellular organism process#GO:0044706;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>Prolactin#P06789 MONDO|Ensembl=ENSMODG00000019310.4|UniProtKB=A0A5F8GYC6 A0A5F8GYC6 FLOT2 PTHR13806:SF46 FLOTILLIN-RELATED FLOTILLIN-2 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000017738.4|UniProtKB=F7EL35 F7EL35 WDR76 PTHR14773:SF0 WD REPEAT-CONTAINING PROTEIN 76 WD REPEAT-CONTAINING PROTEIN 76 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of response to stress#GO:0080134;regulation of cellular response to stress#GO:0080135;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;regulation of cell communication#GO:0010646;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000005013.3|UniProtKB=F7F6L9 F7F6L9 PTHR24320:SF297 RETINOL DEHYDROGENASE RETINOL DEHYDROGENASE 11 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000014917.4|UniProtKB=F7FVU1 F7FVU1 EPS15L1 PTHR11216:SF69 EH DOMAIN EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE 15-LIKE 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular localization#GO:0051641;endosomal transport#GO:0016197;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;clathrin-coated pit#GO:0005905;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;coated membrane#GO:0048475;membrane coat#GO:0030117 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000025431.1|UniProtKB=F6VM20 F6VM20 DIRAS2 PTHR24070:SF178 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN DI-RAS2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000004909.4|UniProtKB=F7BGE4 F7BGE4 PTHR11738:SF199 MHC CLASS I NK CELL RECEPTOR IG-LIKE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000007384.4|UniProtKB=F7G4Y5 F7G4Y5 NADSYN1 PTHR23090:SF9 NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;indole-containing compound metabolic process#GO:0042430;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ligase#PC00142 MONDO|Ensembl=ENSMODG00000028081.2|UniProtKB=K7E692 K7E692 LOC103099908 PTHR47499:SF2 SERINE PROTEASE INHIBITOR KAZAL-TYPE 7 SPINK7 SERINE PROTEASE INHIBITOR KAZAL-TYPE 9 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134 negative regulation of metabolic process#GO:0009892;biological regulation#GO:0065007;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of proteolysis#GO:0030162;negative regulation of cellular process#GO:0048523 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000014313.4|UniProtKB=F7BTW0 F7BTW0 PTHR24351:SF48 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE BETA-1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;TOR signaling#GO:0031929;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular response to insulin stimulus#GO:0032869;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;TORC1 signaling#GO:0038202 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142;PI3 kinase pathway#P00048>S6K#P01194;CCKR signaling map#P06959>p70S6K1#P07031;p53 pathway by glucose deprivation#P04397>S6K#P04636;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888 MONDO|Ensembl=ENSMODG00000041491.1|UniProtKB=A0A5F8HG98 A0A5F8HG98 PTHR12322:SF66 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR B1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;sex differentiation#GO:0007548;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000040832.1|UniProtKB=A0A5F8HIH0 A0A5F8HIH0 PTHR10934:SF2 60S RIBOSOMAL PROTEIN L18 LARGE RIBOSOMAL SUBUNIT PROTEIN EL18 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000010211.4|UniProtKB=F6SAG4 F6SAG4 STOML3 PTHR10264:SF49 BAND 7 PROTEIN-RELATED STOMATIN-LIKE PROTEIN 3 ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000008728.4|UniProtKB=A0A5F8HDX5 A0A5F8HDX5 BTBD10 PTHR21637:SF5 BTB/POZ DOMAIN-CONTAINING PROTEIN 10-RELATED BTB_POZ DOMAIN-CONTAINING PROTEIN 10 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000048363.1|UniProtKB=A0A5F8GBK7 A0A5F8GBK7 VN2R557 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000046019.1|UniProtKB=A0A5F8GQM6 A0A5F8GQM6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000039957.1|UniProtKB=A0A5F8G4W9 A0A5F8G4W9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000002651.5|UniProtKB=F7DI90 F7DI90 NCOA6 PTHR15690:SF0 NUCLEAR RECEPTOR COACTIVATOR 6 NUCLEAR RECEPTOR COACTIVATOR 6 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000017711.4|UniProtKB=F6WSV8 F6WSV8 ETNK1 PTHR22603:SF91 CHOLINE/ETHANOALAMINE KINASE ETHANOLAMINE KINASE 1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137 MONDO|Ensembl=ENSMODG00000001332.4|UniProtKB=A0A5F8G640 A0A5F8G640 MITD1 PTHR21222:SF1 MIT DOMAIN-CONTAINING PROTEIN 1 MIT DOMAIN-CONTAINING PROTEIN 1 cellular component organization#GO:0016043;cell cycle#GO:0007049;cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;membrane organization#GO:0061024;cytokinesis#GO:0000910;cytokinetic process#GO:0032506;mitotic cytokinetic process#GO:1902410;cytoskeleton-dependent cytokinesis#GO:0061640;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047 cellular anatomical structure#GO:0110165;midbody#GO:0030496 MONDO|Ensembl=ENSMODG00000047540.1|UniProtKB=A0A5F8HDM0 A0A5F8HDM0 CD302 PTHR22803:SF144 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED CD302 ANTIGEN membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000021071.3|UniProtKB=F6V1T6 F6V1T6 EPCIP PTHR35658:SF1 RCG58666, ISOFORM CRA_A EXOSOMAL POLYCYSTIN-1-INTERACTING PROTEIN organelle localization#GO:0051640;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;mitochondrion localization#GO:0051646;cellular process#GO:0009987;establishment of organelle localization#GO:0051656;export from cell#GO:0140352 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000006495.2|UniProtKB=F7EKM8 F7EKM8 NANP PTHR46470:SF3 N-ACYLNEURAMINATE-9-PHOSPHATASE N-ACYLNEURAMINATE-9-PHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000028043.1|UniProtKB=K7E2L8 K7E2L8 PTHR35825:SF2 CASEIN KINASE II SUBUNIT ALPHA PRIME-INTERACTING PROTEIN CASEIN KINASE II SUBUNIT ALPHA'-INTERACTING PROTEIN MONDO|Ensembl=ENSMODG00000050288.1|UniProtKB=A0A5F8G437 A0A5F8G437 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025496.3|UniProtKB=F6QYI1 F6QYI1 PTHR13080:SF16 ATP SYNTHASE F CHAIN, MITOCHONDRIAL-RELATED ATP SYNTHASE F(0) COMPLEX SUBUNIT F, MITOCHONDRIAL proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;proton channel activity#GO:0015252 aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;proton motive force-driven ATP synthesis#GO:0015986;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390 cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702 ATP synthase#PC00002 MONDO|Gene=TSHB|UniProtKB=Q95J88 Q95J88 TSHB PTHR11515:SF5 GLYCOPROTEIN HORMONE BETA CHAIN THYROTROPIN SUBUNIT BETA signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 Thyrotropin-releasing hormone receptor signaling pathway#P04394>Thyrotropin#P04588;Thyrotropin-releasing hormone receptor signaling pathway#P04394>ProTRH (Pro Thyrotropin-releasing Hormone)#P04586;Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH#P04585 MONDO|Ensembl=ENSMODG00000047394.1|UniProtKB=F7A2L9 F7A2L9 LOC100028452 PTHR26451:SF210 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000004352.4|UniProtKB=F6WQL2 F6WQL2 GNA13 PTHR10218:SF85 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-13 G protein-coupled receptor binding#GO:0001664;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;protein binding#GO:0005515;hydrolase activity#GO:0016787 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cell projection membrane#GO:0031253;side of membrane#GO:0098552;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;apical plasma membrane#GO:0016324;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;apical part of cell#GO:0045177;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;membrane#GO:0016020;brush border#GO:0005903;cell periphery#GO:0071944;plasma membrane region#GO:0098590;brush border membrane#GO:0031526;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737 G-protein#PC00020;heterotrimeric G-protein#PC00117 MONDO|Ensembl=ENSMODG00000042703.1|UniProtKB=A0A5F8GKL4 A0A5F8GKL4 PTHR22776:SF10 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 8 biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000043793.1|UniProtKB=A0A5F8G7S6 A0A5F8G7S6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000000481.4|UniProtKB=F6UAM7 F6UAM7 CPT2 PTHR22589:SF51 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 2, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000043613.1|UniProtKB=K7DZZ1 K7DZZ1 PTHR25952:SF256 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000003242.2|UniProtKB=F6THU4 F6THU4 CPLANE2 PTHR14983:SF1 CILIOGENESIS AND PLANAR POLARITY EFFECTOR 2 CILIOGENESIS AND PLANAR POLARITY EFFECTOR 2 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 axoneme assembly#GO:0035082;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;ciliary transition zone#GO:0035869;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000017222.4|UniProtKB=F6WXR7 F6WXR7 ACE2 PTHR10514:SF24 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME 2 peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;circulatory system process#GO:0003013;proteolysis#GO:0006508;biosynthetic process#GO:0009058;biological regulation#GO:0065007;protein maturation#GO:0051604;gene expression#GO:0010467;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;hormone metabolic process#GO:0042445;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;peptide hormone processing#GO:0016486;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;system process#GO:0003008;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000024223.2|UniProtKB=A0A5F8H430 A0A5F8H430 ZNF212 PTHR24390:SF49 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 212 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000018831.5|UniProtKB=F7GKB8 F7GKB8 TFAP2B PTHR10812:SF14 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-BETA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of apoptotic process#GO:0043066;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;multicellular organism development#GO:0007275;regulation of apoptotic process#GO:0042981;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000046080.1|UniProtKB=A0A5F8GDA2 A0A5F8GDA2 CHST3 PTHR10704:SF60 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 3 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;amino sugar metabolic process#GO:0006040;primary metabolic process#GO:0044238;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;chondroitin sulfate proteoglycan metabolic process#GO:0050654;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;sulfur compound metabolic process#GO:0006790 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000010107.4|UniProtKB=F6X4I0 F6X4I0 CLTCL1 PTHR10292:SF6 CLATHRIN HEAVY CHAIN RELATED CLATHRIN HEAVY CHAIN 2 protein binding#GO:0005515;binding#GO:0005488;clathrin binding#GO:0030276 transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle#GO:0030136;organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229 vesicle coat protein#PC00235;membrane traffic protein#PC00150 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722 MONDO|Ensembl=ENSMODG00000012431.4|UniProtKB=F6PJX4 F6PJX4 PTHR11461:SF165 SERINE PROTEASE INHIBITOR, SERPIN ALPHA-1-ANTITRYPSIN endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>alpha1-antitrypsin#P00421 MONDO|Ensembl=ENSMODG00000009785.3|UniProtKB=F6SZS5 F6SZS5 GFRA2 PTHR10269:SF4 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-2 signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000049755.1|UniProtKB=A0A5F8GCW0 A0A5F8GCW0 PTHR10015:SF274 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000004870.4|UniProtKB=F6T8D2 F6T8D2 NSD1 PTHR22884:SF312 SET DOMAIN PROTEINS HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 SPECIFIC protein methyltransferase activity#GO:0008276;histone H3K36 methyltransferase activity#GO:0046975;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;lysine N-methyltransferase activity#GO:0016278 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000006345.4|UniProtKB=A0A5F8H3K8 A0A5F8H3K8 ACSS1 PTHR24095:SF110 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE 2-LIKE, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;acetyl-CoA metabolic process#GO:0006084;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ligase#PC00142 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 MONDO|Ensembl=ENSMODG00000006887.4|UniProtKB=F6PVR0 F6PVR0 CRISPLD1 PTHR10334:SF73 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN LCCL DOMAIN-CONTAINING 1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000000721.4|UniProtKB=A0A5F8HFK8 A0A5F8HFK8 LOC100030370 PTHR22855:SF47 ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED METHYLCROTONOYL-COA CARBOXYLASE ligase activity#GO:0016874;catalytic activity#GO:0003824 amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ligase#PC00142;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000016767.3|UniProtKB=A0A5F8HBC7 A0A5F8HBC7 ADAM28 PTHR11905:SF32 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 28 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000044465.1|UniProtKB=A0A5F8HE50 A0A5F8HE50 PTHR11904:SF12 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;nucleoside catabolic process#GO:0009164;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;nucleobase-containing small molecule catabolic process#GO:0034656;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleoside phosphate biosynthetic process#GO:1901293;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyridine-containing compound metabolic process#GO:0072524;purine nucleoside metabolic process#GO:0042278;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 kinase#PC00137;nucleotide kinase#PC00172 Xanthine and guanine salvage pathway#P02788>Guanosine phosphorylase#P03250;Adenine and hypoxanthine salvage pathway#P02723>Deoxyinosine phosphorylase#P02812;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphorylase#P02805;Purine metabolism#P02769>Nucleoside Phosphorylase#P03115;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine phosphorylase#P02808;Adenine and hypoxanthine salvage pathway#P02723>Inosine phosphorylase#P02813;Xanthine and guanine salvage pathway#P02788>Deoxyguanosine phosphorylase#P03248 MONDO|Ensembl=ENSMODG00000017060.3|UniProtKB=F6XHS5 F6XHS5 HCN3 PTHR45689:SF7 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 3 transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832 cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;transmembrane transporter complex#GO:1902495;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transporter complex#GO:1990351;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000005838.4|UniProtKB=F6U1G6 F6U1G6 AP1M2 PTHR10529:SF234 AP COMPLEX SUBUNIT MU AP-1 COMPLEX SUBUNIT MU-2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 post-Golgi vesicle-mediated transport#GO:0006892;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;vacuolar transport#GO:0007034;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 clathrin vesicle coat#GO:0030125;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;vesicle coat#GO:0030120;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;trans-Golgi network transport vesicle membrane#GO:0012510;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;AP-1 adaptor complex#GO:0030121;trans-Golgi network transport vesicle#GO:0030140;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane coat#GO:0030117;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000051085.1|UniProtKB=A0A5F8H1B3 A0A5F8H1B3 CISD3 PTHR46491:SF3 CDGSH IRON SULFUR DOMAIN PROTEIN HOMOLOG CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL iron-sulfur cluster binding#GO:0051536;small molecule binding#GO:0036094;binding#GO:0005488 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 MONDO|Ensembl=ENSMODG00000048295.1|UniProtKB=A0A5F8G6R2 A0A5F8G6R2 LYPD6B PTHR31171:SF3 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 6 LY6_PLAUR DOMAIN-CONTAINING PROTEIN 6B molecular function regulator activity#GO:0098772;neurotransmitter receptor regulator activity#GO:0099602;signaling receptor regulator activity#GO:0030545;acetylcholine receptor regulator activity#GO:0030548 MONDO|Ensembl=ENSMODG00000009514.4|UniProtKB=F7EVK3 F7EVK3 ATF2 PTHR19304:SF9 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302;Gonadotropin-releasing hormone receptor pathway#P06664>ATF2#P06732;Oxidative stress response#P00046>ATF2#P01126;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;CCKR signaling map#P06959>ATF2#P07078;Ras Pathway#P04393>ATF2#P04548 MONDO|Ensembl=ENSMODG00000016267.4|UniProtKB=F7BHD3 F7BHD3 ARFGEF2 PTHR10663:SF124 GUANYL-NUCLEOTIDE EXCHANGE FACTOR BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 2 Golgi to plasma membrane transport#GO:0006893;cellular component organization#GO:0016043;post-Golgi vesicle-mediated transport#GO:0006892;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;organelle organization#GO:0006996;vesicle-mediated transport to the plasma membrane#GO:0098876;endosome organization#GO:0007032;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000007346.4|UniProtKB=F7ADE7 F7ADE7 NALCN PTHR46141:SF1 SODIUM LEAK CHANNEL NON-SELECTIVE PROTEIN SODIUM LEAK CHANNEL NALCN channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of synaptic transmission#GO:0050806;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of trans-synaptic signaling#GO:0099177;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000016556.4|UniProtKB=H9H6Z1 H9H6Z1 PHF5A PTHR13120:SF0 PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114 MONDO|Ensembl=ENSMODG00000008477.4|UniProtKB=F7G4E3 F7G4E3 VN2R537 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005318.3|UniProtKB=F7DLH7 F7DLH7 PTHR10256:SF1 SELENIDE, WATER DIKINASE SELENIDE, WATER DIKINASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000013015.3|UniProtKB=F7C7J9 F7C7J9 PNRC2 PTHR15405:SF6 PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR 2 RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188 intracellular organelle#GO:0043229;P-body#GO:0000932;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000012069.3|UniProtKB=F7G539 F7G539 PTHR13538:SF4 N-ACETYLTRANSFERASE 6 N-ALPHA-ACETYLTRANSFERASE 80 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;N-acetyltransferase activity#GO:0008080;ion binding#GO:0043167;acyltransferase activity#GO:0016746;small molecule binding#GO:0036094;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;protein N-acetyltransferase activity#GO:0034212;transferase activity#GO:0016740;protein N-acyltransferase activity#GO:0140186;nucleoside phosphate binding#GO:1901265;acetyltransferase activity#GO:0016407;binding#GO:0005488 regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000042643.1|UniProtKB=A0A5F8GTS1 A0A5F8GTS1 PTHR23267:SF313 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 5-2 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000015179.4|UniProtKB=F7BWG3 F7BWG3 PGAM5 PTHR20935:SF0 PHOSPHOGLYCERATE MUTASE-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE PGAM5, MITOCHONDRIAL catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;positive regulation of cellular process#GO:0048522;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of mitochondrial fission#GO:0090140;positive regulation of mitochondrial fission#GO:0090141;regulation of developmental process#GO:0050793;positive regulation of cellular component organization#GO:0051130;positive regulation of developmental process#GO:0051094;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of organelle organization#GO:0010638 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 isomerase#PC00135;mutase#PC00160 MONDO|Ensembl=ENSMODG00000000561.3|UniProtKB=F6X4Y4 F6X4Y4 ABCG5 PTHR48041:SF113 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 5 transmembrane transporter activity#GO:0022857;sterol transfer activity#GO:0120015;transporter activity#GO:0005215;cholesterol transfer activity#GO:0120020;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;lipid transfer activity#GO:0120013 cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;cholesterol efflux#GO:0033344;cellular process#GO:0009987;lipid transport#GO:0006869;transport#GO:0006810;chemical homeostasis#GO:0048878;cholesterol homeostasis#GO:0042632;establishment of localization#GO:0051234;sterol transport#GO:0015918;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;lipid localization#GO:0010876;transmembrane transport#GO:0055085;localization#GO:0051179;organic hydroxy compound transport#GO:0015850 ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;apical part of cell#GO:0045177;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;ATP-binding cassette (ABC) transporter complex#GO:0043190;membrane protein complex#GO:0098796;apical plasma membrane#GO:0016324;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000042215.1|UniProtKB=A0A5F8G8H4 A0A5F8G8H4 PTHR13452:SF10 THUMP DOMAIN CONTAINING PROTEIN 1-RELATED THUMP DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-RNA adaptor activity#GO:0140517 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 MONDO|Ensembl=ENSMODG00000047881.1|UniProtKB=A0A5F8G944 A0A5F8G944 monDomV1R1208 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037515.1|UniProtKB=A0A5F8HL32 A0A5F8HL32 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020495.4|UniProtKB=H9H910 H9H910 PTHR11339:SF384 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-2 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000013996.4|UniProtKB=F6VRB5 F6VRB5 UQCC2 PTHR34260:SF1 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 2 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex III assembly#GO:0034551;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000039977.1|UniProtKB=A0A5F8GLB8 A0A5F8GLB8 PTHR15296:SF2 MEMBRANE-ASSOCIATED PROTEIN MAP17 SMALL INTEGRAL MEMBRANE PROTEIN 24 MONDO|Ensembl=ENSMODG00000051233.1|UniProtKB=A0A5F8HFL8 A0A5F8HFL8 PTHR40389:SF3 ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED IGE-BINDING PROTEIN MONDO|Ensembl=ENSMODG00000018927.3|UniProtKB=F7GJV3 F7GJV3 BBS7 PTHR16074:SF4 BARDET-BIEDL SYNDROME 7 PROTEIN BBSOME COMPLEX MEMBER BBS7 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229;BBSome#GO:0034464;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;neuron projection#GO:0043005;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000017312.3|UniProtKB=F6XCN5 F6XCN5 TRAPPC2 PTHR12403:SF1 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-RELATED intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482 intracellular vesicle#GO:0097708;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000020516.4|UniProtKB=F7ENU0 F7ENU0 DUSP6 PTHR10159:SF45 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 6 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;signaling#GO:0023052;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;regulation of apoptotic process#GO:0042981;regulation of MAPK cascade#GO:0043408;positive regulation of apoptotic process#GO:0043065;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;negative regulation of signal transduction#GO:0009968;regulation of multicellular organismal process#GO:0051239;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;regulation of growth#GO:0040008;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000005126.4|UniProtKB=A0A5F8GXG2 A0A5F8GXG2 LY75 PTHR22803:SF65 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED LYMPHOCYTE ANTIGEN 75 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000047889.1|UniProtKB=A0A5F8GT90 A0A5F8GT90 PTHR19944:SF59 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ ALPHA 1 CHAIN peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488;protein-containing complex binding#GO:0044877 cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component assembly#GO:0022607;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;regulation of multicellular organismal process#GO:0051239;positive regulation of leukocyte activation#GO:0002696;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of lymphocyte activation#GO:0051249;immune system process#GO:0002376;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of cell adhesion#GO:0045785;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 MONDO|Ensembl=ENSMODG00000004142.4|UniProtKB=F6PHG0 F6PHG0 PTHR24099:SF14 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FIBRONECTIN TYPE III DOMAIN CONTAINING 3C2-RELATED ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000015284.4|UniProtKB=F6T6N6 F6T6N6 ZNRF2 PTHR46661:SF3 E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE ZNRF2 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000000835.4|UniProtKB=A0A5F8GWL8 A0A5F8GWL8 RAB3GAP1 PTHR21422:SF18 RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;central nervous system development#GO:0007417;positive regulation of macroautophagy#GO:0016239;regulation of cellular component biogenesis#GO:0044087;regulation of autophagosome assembly#GO:2000785;animal gross anatomical part developmental process#GO:0160108;positive regulation of cellular component organization#GO:0051130;positive regulation of metabolic process#GO:0009893;positive regulation of organelle organization#GO:0010638;positive regulation of autophagy#GO:0010508;positive regulation of biological process#GO:0048518;positive regulation of cellular component biogenesis#GO:0044089;nervous system development#GO:0007399;head development#GO:0060322;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of macroautophagy#GO:0016241;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of metabolic process#GO:0019222;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;brain development#GO:0007420;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;developmental process#GO:0032502;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894 GTPase-activating protein#PC00257;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000038348.1|UniProtKB=A0A5F8GLI4 A0A5F8GLI4 PTHR23226:SF425 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 24 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000048735.1|UniProtKB=A0A5F8HBQ5 A0A5F8HBQ5 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000021575.1|UniProtKB=Q65CJ0 Q65CJ0 MT-CO2 PTHR22888:SF9 CYTOCHROME C OXIDASE, SUBUNIT II CYTOCHROME C OXIDASE SUBUNIT 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055 aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;organelle membrane#GO:0031090;transporter complex#GO:1990351 oxidoreductase#PC00176 Gonadotropin-releasing hormone receptor pathway#P06664>COX2#G06899;Gonadotropin-releasing hormone receptor pathway#P06664>COX2#G06686;Gonadotropin-releasing hormone receptor pathway#P06664>COX2#P06734 MONDO|Ensembl=ENSMODG00000013938.2|UniProtKB=F6SCL0 F6SCL0 SMIM29 PTHR47730:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 29 SMALL INTEGRAL MEMBRANE PROTEIN 29 MONDO|Ensembl=ENSMODG00000024403.2|UniProtKB=F6Z3V9 F6Z3V9 PTHR45782:SF4 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;mitochondrial large ribosomal subunit assembly#GO:1902775;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-RNA complex assembly#GO:0022618;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;ribosome biogenesis#GO:0042254;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;ribosomal large subunit assembly#GO:0000027;mitochondrial ribosome assembly#GO:0061668;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000024309.2|UniProtKB=F7EHX9 F7EHX9 LOC100012872 PTHR10210:SF123 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293 transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 MONDO|Ensembl=ENSMODG00000007878.2|UniProtKB=F7EB48 F7EB48 DAGLB PTHR45792:SF2 DIACYLGLYCEROL LIPASE HOMOLOG-RELATED DIACYLGLYCEROL LIPASE-BETA triacylglycerol lipase activity#GO:0004806;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 catabolic process#GO:0009056;primary metabolic process#GO:0044238;system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;neutral lipid metabolic process#GO:0006638;lipid metabolic process#GO:0006629;developmental process#GO:0032502;neutral lipid catabolic process#GO:0046461;acylglycerol metabolic process#GO:0006639;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;cell differentiation#GO:0030154;glycerolipid metabolic process#GO:0046486;arachidonate metabolic process#GO:0019369;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;animal gross anatomical part developmental process#GO:0160108;olefinic compound metabolic process#GO:0120254;glycerolipid catabolic process#GO:0046503;oxoacid metabolic process#GO:0043436;nervous system development#GO:0007399;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;lipid catabolic process#GO:0016042;long-chain fatty acid metabolic process#GO:0001676;acylglycerol catabolic process#GO:0046464;multicellular organism development#GO:0007275;unsaturated fatty acid metabolic process#GO:0033559;metabolic process#GO:0008152 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000012682.5|UniProtKB=F6W2Y5 F6W2Y5 DENND5B PTHR46070:SF3 PINSTRIPE, ISOFORM A DENN DOMAIN-CONTAINING PROTEIN 5B molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085 MONDO|Ensembl=ENSMODG00000024461.1|UniProtKB=F6YIQ8 F6YIQ8 LRRC4C PTHR24369:SF8 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4C binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;modulation of chemical synaptic transmission#GO:0050804;regulation of signaling#GO:0023051;cell adhesion#GO:0007155;synapse organization#GO:0050808;synaptic membrane adhesion#GO:0099560;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;regulation of cell projection organization#GO:0031344;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of axonogenesis#GO:0050770 cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;glutamatergic synapse#GO:0098978;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cell periphery#GO:0071944;membrane#GO:0016020;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000014982.4|UniProtKB=F7CGE0 F7CGE0 PTHR22802:SF445 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 17, MEMBER A pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000007312.3|UniProtKB=F7EXZ6 F7EXZ6 CDH8 PTHR24027:SF273 CADHERIN-23 CADHERIN-8 beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell migration#GO:0016477;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell motility#GO:0048870;cell junction organization#GO:0034330;cell morphogenesis#GO:0000902 cell periphery#GO:0071944;neuron projection#GO:0043005;presynapse#GO:0098793;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;axon terminus#GO:0043679;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;neuron projection terminus#GO:0044306;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;axon#GO:0030424;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000037451.1|UniProtKB=A0A5F8HGP4 A0A5F8HGP4 ARF4 PTHR11711:SF110 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 4 carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 MONDO|Ensembl=ENSMODG00000006789.4|UniProtKB=F6PH52 F6PH52 TOR1B PTHR10760:SF14 TORSIN TORSIN-1B cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 protein localization to organelle#GO:0033365;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;protein localization to nucleus#GO:0034504;cellular component organization#GO:0016043;macromolecule localization#GO:0033036;organelle organization#GO:0006996;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;nuclear envelope organization#GO:0006998;intracellular protein localization#GO:0008104 endoplasmic reticulum#GO:0005783;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;nucleus#GO:0005634;endomembrane system#GO:0012505;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;organelle envelope#GO:0031967;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000009456.3|UniProtKB=A0A5F8HL02 A0A5F8HL02 LIN7C PTHR14063:SF5 PROTEIN LIN-7 HOMOLOG PROTEIN LIN-7 HOMOLOG C molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of growth#GO:0040008;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of developmental process#GO:0050793;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of cell junction assembly#GO:1901888;signal release#GO:0023061;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;localization#GO:0051179;cell communication#GO:0007154;regulation of synapse structure or activity#GO:0050803;secretion#GO:0046903;vesicle localization#GO:0051648;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;regulation of synapse assembly#GO:0051963;transport#GO:0006810;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;signaling#GO:0023052;export from cell#GO:0140352;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;establishment of organelle localization#GO:0051656;regulation of synapse organization#GO:0050807;secretion by cell#GO:0032940;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic vesicle transport#GO:0048489;neurotransmitter transport#GO:0006836;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell junction#GO:0030054 cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000018538.4|UniProtKB=F7GD70 F7GD70 ABCD2 PTHR11384:SF24 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 2 ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;transporter activity#GO:0005215;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;carboxylic acid transmembrane transporter activity#GO:0046943;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monocarboxylic acid transmembrane transporter activity#GO:0008028;nucleotide binding#GO:0000166;transmembrane transporter activity#GO:0022857 cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;fatty acid oxidation#GO:0019395;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;lipid catabolic process#GO:0016042;cellular process#GO:0009987;cellular localization#GO:0051641;transmembrane transport#GO:0055085;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876;peroxisome organization#GO:0007031;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;cellular component organization#GO:0016043;carboxylic acid metabolic process#GO:0019752;lipid modification#GO:0030258;establishment of localization#GO:0051234;intracellular transport#GO:0046907;fatty acid metabolic process#GO:0006631;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;transport#GO:0006810;lipid transport#GO:0006869;monocarboxylic acid catabolic process#GO:0072329;macromolecule localization#GO:0033036;carboxylic acid catabolic process#GO:0046395;fatty acid transport#GO:0015908;localization#GO:0051179;lipid oxidation#GO:0034440;peroxisomal transport#GO:0043574;monocarboxylic acid transport#GO:0015718;catabolic process#GO:0009056;carboxylic acid transmembrane transport#GO:1905039;primary metabolic process#GO:0044238 peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000009863.4|UniProtKB=F6VTX1 F6VTX1 PXDNL PTHR11475:SF38 OXIDASE/PEROXIDASE OXIDOREDUCTASE PXDNL-RELATED oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000049411.1|UniProtKB=A0A5F8HEP6 A0A5F8HEP6 PTHR19446:SF479 REVERSE TRANSCRIPTASES RNA-DIRECTED DNA POLYMERASE reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000046343.1|UniProtKB=A0A5F8H1M5 A0A5F8H1M5 PTHR26453:SF161 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T29-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015501.3|UniProtKB=F6WEN6 F6WEN6 TMBIM1 PTHR23291:SF35 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 3 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;transporter activity#GO:0005215 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of extrinsic apoptotic signaling pathway#GO:2001236;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;negative regulation of apoptotic signaling pathway#GO:2001234;cellular response to topologically incorrect protein#GO:0035967;regulation of apoptotic signaling pathway#GO:2001233;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;endoplasmic reticulum unfolded protein response#GO:0030968;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;response to unfolded protein#GO:0006986;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;negative regulation of neuron apoptotic process#GO:0043524;regulation of apoptotic process#GO:0042981 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000010672.5|UniProtKB=F7CJX4 F7CJX4 ZNF774 PTHR24377:SF924 IP01015P-RELATED ZINC FINGER PROTEIN 774 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018036.4|UniProtKB=F6ZWF2 F6ZWF2 HACE1 PTHR11254:SF363 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HACE1 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular process#GO:0009987;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ubiquitin-dependent protein catabolic process#GO:0006511;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;Golgi organization#GO:0007030;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538 membrane#GO:0016020;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000001050.3|UniProtKB=F6YRU7 F6YRU7 PTHR35678:SF1 PROTEIN STPG4 PROTEIN STPG4 binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;biological regulation#GO:0065007;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000021482.4|UniProtKB=A0A5F8GFY3 A0A5F8GFY3 THOC1 PTHR13265:SF2 THO COMPLEX SUBUNIT 1 THO COMPLEX SUBUNIT 1 biosynthetic process#GO:0009058;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913 transcription export complex#GO:0000346;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;THO complex#GO:0000347;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000017647.5|UniProtKB=F6YKI7 F6YKI7 PTHR45851:SF5 MYC PROTO-ONCOGENE PROTEIN L-MYC-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 MONDO|Ensembl=ENSMODG00000006484.4|UniProtKB=F7F2L3 F7F2L3 PTHR24271:SF59 KALLIKREIN-RELATED KALLIKREIN-5 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000000406.4|UniProtKB=F6QMJ8 F6QMJ8 RALGAPB PTHR21344:SF1 RAL GTPASE-ACTIVATING PROTEIN SUBUNIT BETA RAL GTPASE-ACTIVATING PROTEIN SUBUNIT BETA molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 MONDO|Ensembl=ENSMODG00000003909.4|UniProtKB=F7CNX3 F7CNX3 PTHR21184:SF4 MENORIN (DENDRITIC BRANCHING PROTEIN) PROTEIN FAM151A cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000019665.4|UniProtKB=F6TUP8 F6TUP8 SREK1 PTHR32343:SF71 SERINE/ARGININE-RICH SPLICING FACTOR SPLICING REGULATORY GLUTAMINE_LYSINE-RICH PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000008294.4|UniProtKB=F6Q811 F6Q811 PTHR11829:SF68 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN C1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000041237.1|UniProtKB=A0A5F8G5B9 A0A5F8G5B9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000017671.3|UniProtKB=F7GFZ3 F7GFZ3 DUOXA2 PTHR31158:SF2 DUAL OXIDASE 2 DUAL OXIDASE MATURATION FACTOR 2 membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidase#PC00175;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000019548.4|UniProtKB=F6UTW0 F6UTW0 KIF7 PTHR24115:SF445 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF7 isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000010692.4|UniProtKB=F7C0N5 F7C0N5 TFPI PTHR10083:SF328 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED TISSUE FACTOR PATHWAY INHIBITOR enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 Blood coagulation#P00011>TFPI#P00417 MONDO|Ensembl=ENSMODG00000014217.3|UniProtKB=F6T9S7 F6T9S7 LOC100619324 PTHR23262:SF248 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-6 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000001856.3|UniProtKB=F6SP03 F6SP03 KAT8 PTHR10615:SF82 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT8 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746 NSL complex#GO:0044545;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000028212.2|UniProtKB=F7BYN4 F7BYN4 STAT3 PTHR11801:SF2 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;response to peptide hormone#GO:0043434;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to nitrogen compound#GO:1901699;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;defense response#GO:0006952;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;interleukin-2-mediated signaling pathway#GO:0038110;cellular response to stimulus#GO:0051716;cellular response to peptide hormone stimulus#GO:0071375;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cytokine-mediated signaling pathway#GO:0019221;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to stress#GO:0006950;response to hormone#GO:0009725;interleukin-9-mediated signaling pathway#GO:0038113;cell surface receptor signaling pathway via STAT#GO:0097696;response to chemical#GO:0042221;response to cytokine#GO:0034097;cell surface receptor signaling pathway#GO:0007166;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to hormone stimulus#GO:0032870;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to peptide#GO:1901652 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Interleukin signaling pathway#P00036>STAT#P00996;CCKR signaling map#P06959>STAT3#P07165;Ras Pathway#P04393>Stat 1/3#P04566;Gonadotropin-releasing hormone receptor pathway#P06664>STAT3#P06795;PDGF signaling pathway#P00047>STAT#P01173;EGF receptor signaling pathway#P00018>STAT#P00561;Angiogenesis#P00005>STAT3#P00217;JAK/STAT signaling pathway#P00038>STAT#P01027;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>STAT#P00832 MONDO|Ensembl=ENSMODG00000011073.3|UniProtKB=F7E691 F7E691 TTI2 PTHR32226:SF2 TELO2-INTERACTING PROTEIN 2 TELO2-INTERACTING PROTEIN 2 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000014302.4|UniProtKB=F6W4N6 F6W4N6 RPS6KA6 PTHR24351:SF98 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-6 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;TOR signaling#GO:0031929;biological regulation#GO:0065007;DNA damage response#GO:0006974;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;cell communication#GO:0007154;TORC1 signaling#GO:0038202;intracellular signal transduction#GO:0035556 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;Ras Pathway#P04393>p90RSK#P04541;Interleukin signaling pathway#P00036>p90RSK#P00964 MONDO|Ensembl=ENSMODG00000009583.3|UniProtKB=F7AWC1 F7AWC1 PNLIP PTHR11610:SF147 LIPASE PANCREATIC TRIACYLGLYCEROL LIPASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000039084.1|UniProtKB=F7CHX1 F7CHX1 PTHR24100:SF64 BUTYROPHILIN BUTYROPHILIN, SUBFAMILY 3, MEMBER A3-RELATED signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000005566.4|UniProtKB=F7F3N7 F7F3N7 GCG PTHR11418:SF0 GLUCAGON PRO-GLUCAGON G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;binding#GO:0005488;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515 regulation of transport#GO:0051049;regulation of localization#GO:0032879;glucose homeostasis#GO:0042593;positive regulation of protein secretion#GO:0050714;chemical homeostasis#GO:0048878;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;signal transduction#GO:0007165;positive regulation of secretion by cell#GO:1903532;cellular process#GO:0009987;regulation of insulin secretion#GO:0050796;regulation of protein localization#GO:0032880;intracellular glucose homeostasis#GO:0001678;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;positive regulation of metabolic process#GO:0009893;regulation of hormone secretion#GO:0046883;positive regulation of signaling#GO:0023056;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of protein transport#GO:0051223;regulation of biological process#GO:0050789;carbohydrate homeostasis#GO:0033500;regulation of hormone levels#GO:0010817;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;regulation of biosynthetic process#GO:0009889;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of carbohydrate metabolic process#GO:0006109;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of establishment of protein localization#GO:0070201;positive regulation of biosynthetic process#GO:0009891;regulation of secretion#GO:0051046;cell communication#GO:0007154;positive regulation of hormone secretion#GO:0046887;regulation of carbohydrate biosynthetic process#GO:0043255;homeostatic process#GO:0042592;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;regulation of protein secretion#GO:0050708 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 CCKR signaling map#P06959>GCG#G07291;CCKR signaling map#P06959>GCG#G06997 MONDO|Ensembl=ENSMODG00000038201.1|UniProtKB=A0A5F8GH99 A0A5F8GH99 PTHR47696:SF4 THAP DOMAIN-CONTAINING PROTEIN 2 THAP DOMAIN CONTAINING 2 MONDO|Ensembl=ENSMODG00000008327.4|UniProtKB=F7F315 F7F315 PTHR13924:SF10 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN microtubule-based process#GO:0007017;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cytoplasmic microtubule organization#GO:0031122 microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000002209.4|UniProtKB=F7G3M0 F7G3M0 ITPK1 PTHR14217:SF1 INOSITOL-TETRAKISPHOSPHATE 1-KINASE INOSITOL-TETRAKISPHOSPHATE 1-KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000007608.4|UniProtKB=F7GHL3 F7GHL3 FAM168A PTHR31844:SF1 MYELIN-ASSOCIATED NEURITE-OUTGROWTH INHIBITOR-RELATED PROTEIN FAM168A regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;positive regulation of DNA metabolic process#GO:0051054;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of response to stress#GO:0080134;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of DNA repair#GO:0045739;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219 structural protein#PC00211;myelin protein#PC00161 MONDO|Ensembl=ENSMODG00000051595.1|UniProtKB=A0A5F8G639 A0A5F8G639 PTHR12787:SF0 RIBOSOMAL RNA-PROCESSING PROTEIN 8 RIBOSOMAL RNA-PROCESSING PROTEIN 8 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a rRNA#GO:0140102;rRNA (adenine) methyltransferase activity#GO:0016433 chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;nucleolus organization#GO:0007000;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of gene expression#GO:0010468;nucleus organization#GO:0006997;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000002274.4|UniProtKB=F7CVW1 F7CVW1 SNTB1 PTHR10554:SF11 SYNTROPHIN BETA-1-SYNTROPHIN cell junction#GO:0030054;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000016253.4|UniProtKB=F7DMJ3 F7DMJ3 SYNE1 PTHR14514:SF3 PKA ANCHORING PROTEIN NESPRIN-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 cellular process#GO:0009987;regulation of organelle assembly#GO:1902115;establishment of localization in cell#GO:0051649;biological regulation#GO:0065007;intracellular transport#GO:0046907;regulation of cilium assembly#GO:1902017;regulation of cell projection organization#GO:0031344;transport#GO:0006810;establishment of localization#GO:0051234;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of organelle organization#GO:0033043;nuclear migration#GO:0007097;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;establishment of organelle localization#GO:0051656;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;centrosome localization#GO:0051642;organelle localization#GO:0051640;cellular localization#GO:0051641;localization#GO:0051179;regulation of cell projection assembly#GO:0060491 organelle membrane#GO:0031090;nuclear membrane#GO:0031965;membraneless organelle#GO:0043228;sarcomere#GO:0030017;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nuclear envelope#GO:0005635;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;supramolecular complex#GO:0099080;nucleus#GO:0005634;contractile muscle fiber#GO:0043292;sarcoplasmic reticulum#GO:0016529;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;myofibril#GO:0030016;intracellular organelle#GO:0043229;sarcoplasm#GO:0016528;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967 MONDO|Ensembl=ENSMODG00000025305.2|UniProtKB=F7EPG6 F7EPG6 PTHR12010:SF2 40S RIBOSOMAL PROTEIN S29 SMALL RIBOSOMAL SUBUNIT PROTEIN US14 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;zinc ion binding#GO:0008270;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000010545.4|UniProtKB=F7CNC9 F7CNC9 PTHR11905:SF136 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 9 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 reproductive structure development#GO:0048608;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;reproductive system development#GO:0061458;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;proteolysis#GO:0006508;multicellular organismal process#GO:0032501;gonad development#GO:0008406;cellular process#GO:0009987;sex differentiation#GO:0007548;male gonad development#GO:0008584;animal organ development#GO:0048513;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;metabolic process#GO:0008152;development of primary male sexual characteristics#GO:0046546;male sex differentiation#GO:0046661;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137 external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 Alzheimer disease-amyloid secretase pathway#P00003>MDC9#P00090 MONDO|Ensembl=ENSMODG00000018029.4|UniProtKB=F6ZWK9 F6ZWK9 PRDM1 PTHR16515:SF59 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 1 biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000023576.2|UniProtKB=F7DBF4 F7DBF4 PTHR12990:SF10 ARMET-LIKE PROTEIN MESENCEPHALIC ASTROCYTE-DERIVED NEUROTROPHIC FACTOR growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 cellular component organization#GO:0016043;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000050906.1|UniProtKB=A0A5F8HDK6 A0A5F8HDK6 PTHR13025:SF5 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN-CONTAINING PROTEIN D1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000037916.1|UniProtKB=A0A5F8HLG3 A0A5F8HLG3 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000037422.1|UniProtKB=A0A5F8GLD7 A0A5F8GLD7 PTHR26452:SF52 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000019625.3|UniProtKB=F6XPX0 F6XPX0 RGS7BP PTHR21029:SF12 R-SEVEN BINDING PROTEIN (R7BP) HOMOLOG REGULATOR OF G PROTEIN SIGNALING 7-BINDING PROTEIN biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;neuron projection#GO:0043005;nucleus#GO:0005634;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202 MONDO|Ensembl=ENSMODG00000011710.3|UniProtKB=F7G3G4 F7G3G4 CRABP1 PTHR11955:SF62 FATTY ACID BINDING PROTEIN CELLULAR RETINOIC ACID-BINDING PROTEIN 1 organic acid binding#GO:0043177;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;lipid binding#GO:0008289;fatty acid binding#GO:0005504 macromolecule localization#GO:0033036;lipid transport#GO:0006869;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;lipid localization#GO:0010876;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;fatty acid transport#GO:0015908;localization#GO:0051179 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000007920.4|UniProtKB=F7GIB9 F7GIB9 SGK3 PTHR24356:SF121 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE SGK3 protein serine/threonine kinase activity#GO:0004674;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;phosphotransferase activity, alcohol group as acceptor#GO:0016773;channel regulator activity#GO:0016247;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;ion channel regulator activity#GO:0099106;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000001608.3|UniProtKB=F7BAH6 F7BAH6 PTHR26453:SF171 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011745.4|UniProtKB=A0A5F8GV03 A0A5F8GV03 GKN1 PTHR16483:SF1 GASTROKINE 1 GASTROKINE-1 regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000045613.1|UniProtKB=F6Q2I3 F6Q2I3 LOC100024049 PTHR26450:SF170 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E8 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013496.4|UniProtKB=F7F8J5 F7F8J5 C6orf89 PTHR35259:SF1 BOMBESIN RECEPTOR-ACTIVATED PROTEIN C6ORF89 BOMBESIN RECEPTOR-ACTIVATED PROTEIN C6ORF89 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 MONDO|Ensembl=ENSMODG00000046250.1|UniProtKB=K7E0I4 K7E0I4 PTHR19367:SF24 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 8-4 immune response#GO:0006955;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000000783.4|UniProtKB=F6SSG1 F6SSG1 PTHR11653:SF2 PARVALBUMIN ALPHA PARVALBUMIN ALPHA cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000001308.5|UniProtKB=F7BZI4 F7BZI4 LONP1 PTHR43718:SF2 LON PROTEASE LON PROTEASE HOMOLOG, MITOCHONDRIAL hydrolase activity#GO:0016787;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000008764.4|UniProtKB=A0A5F8H8E8 A0A5F8H8E8 BAG3 PTHR12329:SF12 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 3 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;enzyme regulator activity#GO:0030234 cellular homeostasis#GO:0019725;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;homeostatic process#GO:0042592;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of protein stability#GO:0031647;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789 nucleus#GO:0005634;cytosol#GO:0005829;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 Apoptosis signaling pathway#P00006>Bag#P00278 MONDO|Ensembl=ENSMODG00000006985.3|UniProtKB=F6QAS0 F6QAS0 PTHR28359:SF1 ASHWIN TRNA-SPLICING LIGASE COMPLEX SUBUNIT ASW RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;RNA splicing#GO:0008380 catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000002652.4|UniProtKB=F7DI83 F7DI83 PTHR12011:SF455 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E3 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000008750.3|UniProtKB=F6PSG2 F6PSG2 MORN2 PTHR46917:SF1 MORN REPEAT-CONTAINING PROTEIN 2 MORN REPEAT-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000017094.4|UniProtKB=F6V365 F6V365 TRIM62 PTHR24103:SF573 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM62 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;innate immune response#GO:0045087;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;regulation of canonical NF-kappaB signal transduction#GO:0043122;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000011614.3|UniProtKB=F6UGV7 F6UGV7 WDR82 PTHR19861:SF0 WD40 REPEAT PROTEIN SWD2 WD REPEAT-CONTAINING PROTEIN 82 binding#GO:0005488;chromatin binding#GO:0003682 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000013221.3|UniProtKB=F7EDF1 F7EDF1 SASH3 PTHR12301:SF5 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED SAM AND SH3 DOMAIN-CONTAINING PROTEIN 3 regulation of lymphocyte activation#GO:0051249;positive regulation of adaptive immune response#GO:0002821;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;positive regulation of cell population proliferation#GO:0008284;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of B cell activation#GO:0050864;regulation of mononuclear cell proliferation#GO:0032944;regulation of leukocyte proliferation#GO:0070663;positive regulation of mononuclear cell proliferation#GO:0032946;positive regulation of leukocyte activation#GO:0002696;regulation of B cell proliferation#GO:0030888;positive regulation of B cell proliferation#GO:0030890;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of lymphocyte activation#GO:0051251;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte proliferation#GO:0050671;regulation of immune response#GO:0050776;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;regulation of lymphocyte proliferation#GO:0050670;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte proliferation#GO:0070665 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000002387.4|UniProtKB=F7F000 F7F000 PTHR11738:SF199 MHC CLASS I NK CELL RECEPTOR IG-LIKE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000039439.1|UniProtKB=A0A5F8HHF5 A0A5F8HHF5 PPP6C PTHR45619:SF67 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 6 CATALYTIC SUBUNIT phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 EGF receptor signaling pathway#P00018>PP2A#P00547 MONDO|Ensembl=ENSMODG00000018815.3|UniProtKB=A0A5F8GW95 A0A5F8GW95 LOC100017050 PTHR11571:SF99 GLUTATHIONE S-TRANSFERASE GLUTATHIONE TRANSFERASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;glutathione metabolic process#GO:0006749;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887 transferase#PC00220 MONDO|Ensembl=ENSMODG00000015653.3|UniProtKB=F7F0T7 F7F0T7 LOC100029233 PTHR10782:SF12 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS2 ubiquitin-like protein ligase activity#GO:0061659;molecular function inhibitor activity#GO:0140678;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;post-translational protein modification#GO:0043687;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;negative regulation of biological process#GO:0048519;protein sumoylation#GO:0016925;metabolic process#GO:0008152;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987 organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958;JAK/STAT signaling pathway#P00038>PIAS#P01031 MONDO|Ensembl=ENSMODG00000020643.4|UniProtKB=A0A5F8H2B5 A0A5F8H2B5 DCUN1D4 PTHR12281:SF8 RP42 RELATED DCN1-LIKE PROTEIN 4 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein binding#GO:0005515;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of macromolecule metabolic process#GO:0010604;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of protein modification process#GO:0031399;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000012883.4|UniProtKB=F6ZNY3 F6ZNY3 ITFG1 PTHR13412:SF0 T-CELL IMMUNOMODULATORY PROTEIN HOMOLOG T-CELL IMMUNOMODULATORY PROTEIN cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000037327.1|UniProtKB=A0A5F8G286 A0A5F8G286 LOC103092424 PTHR24393:SF100 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 345-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000015342.4|UniProtKB=F6XEK6 F6XEK6 NOC4L PTHR12455:SF0 NUCLEOLAR COMPLEX PROTEIN 4 NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;gene expression#GO:0010467 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;small-subunit processome#GO:0032040;90S preribosome#GO:0030686;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000013178.4|UniProtKB=F6ZL39 F6ZL39 GLP1R PTHR45620:SF25 PDF RECEPTOR-LIKE PROTEIN-RELATED GLUCAGON-LIKE PEPTIDE 1 RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of blood pressure#GO:0045777;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008792.2|UniProtKB=A0A5F8H0T8 A0A5F8H0T8 PTHR47888:SF1 UPF0730 PROTEIN ENCODED BY LINC00643-RELATED SERTA DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000020875.4|UniProtKB=A0A5F8G7C8 A0A5F8G7C8 ADCYAP1R1 PTHR45620:SF12 PDF RECEPTOR-LIKE PROTEIN-RELATED PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE TYPE I RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>PAC1R#G06898;Gonadotropin-releasing hormone receptor pathway#P06664>PAC1-R#P06712;Gonadotropin-releasing hormone receptor pathway#P06664>PAC1R#G06685 MONDO|Ensembl=ENSMODG00000041647.1|UniProtKB=A0A5F8GMT9 A0A5F8GMT9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000049005.1|UniProtKB=A8E6E7 A8E6E7 LOC100021368 PTHR11691:SF37 TYPE I INTERFERON INTERFERON OMEGA-1 cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 leukocyte activation involved in immune response#GO:0002366;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;natural killer cell activation#GO:0030101;humoral immune response#GO:0006959;B cell activation#GO:0042113;cellular process#GO:0009987;lymphocyte activation involved in immune response#GO:0002285;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;T cell activation involved in immune response#GO:0002286;defense response to other organism#GO:0098542;lymphocyte activation#GO:0046649;response to chemical#GO:0042221;response to cytokine#GO:0034097;B cell activation involved in immune response#GO:0002312;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;cell activation involved in immune response#GO:0002263;response to peptide#GO:1901652;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;T cell activation#GO:0042110;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune response#GO:0006955;response to other organism#GO:0051707;adaptive immune response#GO:0002250;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell activation#GO:0001775;cytokine-mediated signaling pathway#GO:0019221;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083;interferon superfamily#PC00127 MONDO|Ensembl=ENSMODG00000018280.4|UniProtKB=F6RNA3 F6RNA3 PTHR10829:SF5 CORTACTIN AND DREBRIN HEMATOPOIETIC LINEAGE CELL-SPECIFIC PROTEIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament polymerization#GO:0030833;cell migration#GO:0016477 intracellular organelle#GO:0043229;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;actin filament#GO:0005884;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;membrane#GO:0016020;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000022914.1|UniProtKB=F6PZS2 F6PZS2 LOC100619071 PTHR26450:SF76 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51B5 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016410.4|UniProtKB=A0A5F8GC73 A0A5F8GC73 CBLN4 PTHR22923:SF3 CEREBELLIN-RELATED CEREBELLIN-4 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019004.4|UniProtKB=F7CP75 F7CP75 GSR PTHR42737:SF2 GLUTATHIONE REDUCTASE GLUTATHIONE REDUCTASE, MITOCHONDRIAL nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;disulfide oxidoreductase activity#GO:0015036;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;sulfur compound metabolic process#GO:0006790;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;glutathione metabolic process#GO:0006749;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;modified amino acid metabolic process#GO:0006575;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;homeostatic process#GO:0042592 mitochondrion#GO:0005739;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000016673.3|UniProtKB=F7E6P1 F7E6P1 ADRA1A PTHR24248:SF16 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-1A ADRENERGIC RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;regulation of biological quality#GO:0065008;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 MONDO|Ensembl=ENSMODG00000017241.3|UniProtKB=F6U1K2 F6U1K2 CFAP141 PTHR35818:SF1 C1ORF189 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 141 MONDO|Ensembl=ENSMODG00000015304.4|UniProtKB=F6QDD3 F6QDD3 MBNL3 PTHR12675:SF3 MUSCLEBLIND-LIKE PROTEIN MUSCLEBLIND-LIKE PROTEIN 3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000047481.1|UniProtKB=K7DZD9 K7DZD9 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000014939.4|UniProtKB=H9H6Q3 H9H6Q3 KREMEN1 PTHR24269:SF13 KREMEN PROTEIN KREMEN PROTEIN 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Kremen#P01463 MONDO|Ensembl=ENSMODG00000012192.4|UniProtKB=F7CEH7 F7CEH7 DIABLO PTHR32247:SF3 DIABLO HOMOLOG, MITOCHONDRIAL DIABLO IAP-BINDING MITOCHONDRIAL PROTEIN apoptotic signaling pathway#GO:0097190;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;intrinsic apoptotic signaling pathway#GO:0097193;neuron apoptotic process#GO:0051402;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 Apoptosis signaling pathway#P00006>Smac/Diablo#P00309 MONDO|Ensembl=ENSMODG00000015233.4|UniProtKB=F6V2U1 F6V2U1 GCC1 PTHR23157:SF25 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000010014.4|UniProtKB=F6UAF5 F6UAF5 TIMM22 PTHR14110:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977 cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;mitochondrial transport#GO:0006839;transport#GO:0006810;intracellular transport#GO:0046907;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;organelle organization#GO:0006996;mitochondrial protein import pathway#GO:7770058;protein insertion into mitochondrial inner membrane#GO:0045039;membrane organization#GO:0061024;mitochondrion organization#GO:0007005 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;TIM22 mitochondrial import inner membrane insertion complex#GO:0042721;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 transporter#PC00227 MONDO|Ensembl=ENSMODG00000042861.1|UniProtKB=A0A5F8GTJ5 A0A5F8GTJ5 NDNF PTHR14619:SF1 NEURON-DERIVED NEUROTROPHIC FACTOR PROTEIN NDNF heparin binding#GO:0008201;binding#GO:0005488;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 MONDO|Ensembl=ENSMODG00000008424.4|UniProtKB=F7EX64 F7EX64 monDomV1R1234 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001547.4|UniProtKB=A0A5F8GAG4 A0A5F8GAG4 DHRS7C PTHR44668:SF2 FAMILY NOT NAMED DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7C MONDO|Ensembl=ENSMODG00000040465.1|UniProtKB=A0A5F8G2X1 A0A5F8G2X1 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004416.4|UniProtKB=F6SV17 F6SV17 WDR31 PTHR19869:SF1 SPERMATID WD-REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 31 MONDO|Ensembl=ENSMODG00000015187.4|UniProtKB=F7BW11 F7BW11 ETV4 PTHR11849:SF181 ETS ETS TRANSLOCATION VARIANT 4 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000003807.4|UniProtKB=A0A5F8GW50 A0A5F8GW50 CRTAC1 PTHR16026:SF5 CARTILAGE ACIDIC PROTEIN 1 CARTILAGE ACIDIC PROTEIN 1 anatomical structure development#GO:0048856;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell recognition#GO:0008037;generation of neurons#GO:0048699;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000001885.5|UniProtKB=A0A5F8GLS5 A0A5F8GLS5 CCDC88A PTHR18947:SF30 HOOK PROTEINS GIRDIN cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 cellular component organization#GO:0016043;cytoplasmic microtubule organization#GO:0031122;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000015068.4|UniProtKB=F7FHI9 F7FHI9 ORC2 PTHR14052:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular process#GO:0009987;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270 nuclear origin of replication recognition complex#GO:0005664;origin recognition complex#GO:0000808;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 replication origin binding protein#PC00199 MONDO|Ensembl=ENSMODG00000004362.4|UniProtKB=A0A5F8GX58 A0A5F8GX58 GIT2 PTHR46097:SF4 G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP ARF GTPASE-ACTIVATING PROTEIN GIT2 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme binding#GO:0019899;binding#GO:0005488;molecular function activator activity#GO:0140677;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 regulation of small GTPase mediated signal transduction#GO:0051056;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of response to stimulus#GO:0048583;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;regulation of G protein-coupled receptor signaling pathway#GO:0008277;developmental process#GO:0032502;nervous system development#GO:0007399;head development#GO:0060322;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;synaptic vesicle recycling#GO:0036465;brain development#GO:0007420;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;system development#GO:0048731;anatomical structure development#GO:0048856;cellular localization#GO:0051641;localization#GO:0051179;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;central nervous system development#GO:0007417;regulation of biological process#GO:0050789 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000013522.4|UniProtKB=F7D704 F7D704 CIAPIN1 PTHR13273:SF14 ANAMORSIN ANAMORSIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000001630.4|UniProtKB=F7AMU4 F7AMU4 GUCY1B1 PTHR45655:SF2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-1 lyase activity#GO:0016829;guanylate cyclase activity#GO:0004383;catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849 cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;response to oxygen levels#GO:0070482;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cyclic nucleotide biosynthetic process#GO:0009190;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;response to abiotic stimulus#GO:0009628;phosphorus metabolic process#GO:0006793;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cyclic purine nucleotide metabolic process#GO:0052652;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390 catalytic complex#GO:1902494;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cyclase#PC00079;guanylate cyclase#PC00114 Endothelin signaling pathway#P00019>Guanylate cyclase#P00581;Gonadotropin-releasing hormone receptor pathway#P06664>GC#P06726 MONDO|Ensembl=ENSMODG00000024765.2|UniProtKB=F7DAZ5 F7DAZ5 LOC100025423 PTHR12884:SF18 60S RIBOSOMAL PROTEIN L29 60S RIBOSOMAL PROTEIN L29 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000015774.3|UniProtKB=F6Z4T6 F6Z4T6 LTB PTHR11471:SF29 TUMOR NECROSIS FACTOR FAMILY MEMBER LYMPHOTOXIN-BETA cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of apoptotic process#GO:0043065;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Apoptosis signaling pathway#P00006>TNF#P00259 MONDO|Ensembl=ENSMODG00000009612.5|UniProtKB=F6S0I6 F6S0I6 RB1CC1 PTHR13222:SF5 RB1-INDUCIBLE COILED-COIL RB1-INDUCIBLE COILED-COIL PROTEIN 1 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 reticulophagy#GO:0061709;glycogen catabolic process#GO:0005980;macroautophagy#GO:0016236;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;piecemeal microautophagy of the nucleus#GO:0034727;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;vacuole organization#GO:0007033;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052 protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;phagophore assembly site#GO:0000407;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020638.4|UniProtKB=F7EMP3 F7EMP3 FRYL PTHR12295:SF9 FURRY-RELATED PROTEIN FURRY HOMOLOG-LIKE multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;generation of neurons#GO:0048699 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell division site#GO:0032153;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000050619.1|UniProtKB=A0A5F8H3A0 A0A5F8H3A0 MFNG PTHR10811:SF6 FRINGE-RELATED BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE MANIC FRINGE acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 transferase#PC00220;glycosyltransferase#PC00111 Notch signaling pathway#P00045>Fringe#P01107 MONDO|Ensembl=ENSMODG00000023027.3|UniProtKB=F6UXG2 F6UXG2 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010747.3|UniProtKB=H9H6F0 H9H6F0 PTHR22437:SF1 WINGED HELIX DOMAIN-CONTAINING PROTEIN STORKHEAD-BOX PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000039480.1|UniProtKB=A0A5F8H784 A0A5F8H784 PTHR14122:SF1 GHRELIN PRECURSOR APPETITE-REGULATING HORMONE receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179 positive regulation of cellular component biogenesis#GO:0044089;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;positive regulation of transport#GO:0051050;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;response to stimulus#GO:0050896;regulation of cellular component biogenesis#GO:0044087;positive regulation of multicellular organismal process#GO:0051240;regulation of hormone levels#GO:0010817;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of hormone secretion#GO:0046883;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;regulation of synapse organization#GO:0050807;regulation of signaling#GO:0023051;positive regulation of secretion#GO:0051047;positive regulation of cellular component organization#GO:0051130;regulation of synapse assembly#GO:0051963;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;response to nutrient levels#GO:0031667;positive regulation of cellular process#GO:0048522;positive regulation of synapse assembly#GO:0051965;regulation of response to stimulus#GO:0048583;positive regulation of developmental process#GO:0051094;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;regulation of secretion#GO:0051046;regulation of cell junction assembly#GO:1901888;positive regulation of hormone secretion#GO:0046887 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 MONDO|Ensembl=ENSMODG00000013780.4|UniProtKB=F6TUY9 F6TUY9 PTHR10663:SF338 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 4 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;cell projection membrane#GO:0031253;ruffle#GO:0001726;ruffle membrane#GO:0032587;leading edge membrane#GO:0031256 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000003614.3|UniProtKB=A0A5F8H2C9 A0A5F8H2C9 PPP3R1 PTHR45942:SF1 Calcineurin subunit B PROTEIN PHOSPHATASE 3 REGULATORY SUBUNIT B, ALPHA protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208 intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;calcineurin-mediated signaling#GO:0097720 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 Wnt signaling pathway#P00057>Calcineurin#P01446 MONDO|Ensembl=ENSMODG00000013116.2|UniProtKB=F7BMQ9 F7BMQ9 GJD3 PTHR11984:SF5 CONNEXIN GAP JUNCTION DELTA-3 PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 regulation of biological process#GO:0050789;cellular process#GO:0009987;cell communication#GO:0007154;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 gap junction#PC00105;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000015833.3|UniProtKB=A0A5F8GAV7 A0A5F8GAV7 LOC100020631 PTHR23337:SF7 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 1 ATPASE MORC2 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000040437.1|UniProtKB=A0A5F8GRD0 A0A5F8GRD0 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000022776.3|UniProtKB=A0A5F8GMR3 A0A5F8GMR3 PTHR24356:SF170 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C ZETA TYPE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;establishment of cell polarity#GO:0030010;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;protein localization to plasma membrane#GO:0072659;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;localization#GO:0051179;cell communication#GO:0007154;localization within membrane#GO:0051668;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;cellular response to nitrogen compound#GO:1901699;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;cellular response to insulin stimulus#GO:0032869;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657;response to endogenous stimulus#GO:0009719;cellular localization#GO:0051641;response to oxygen-containing compound#GO:1901700;establishment or maintenance of cell polarity#GO:0007163;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725;protein localization to cell periphery#GO:1990778 non-receptor serine/threonine protein kinase#PC00167 Endothelin signaling pathway#P00019>PKC#P00568;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKCzeta#P00829;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKC#P00861;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109 MONDO|Ensembl=ENSMODG00000006201.4|UniProtKB=F6T086 F6T086 PTHR11143:SF11 60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL24 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000047005.1|UniProtKB=A0A5F8HJW2 A0A5F8HJW2 PTHR24419:SF18 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE SERINE_THREONINE-PROTEIN KINASE HASPIN protein serine/threonine kinase activity#GO:0004674;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;biological regulation#GO:0065007;signaling#GO:0023052 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000045697.1|UniProtKB=A0A5F8H976 A0A5F8H976 PTHR18945:SF764 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3E passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324 establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789 signaling receptor complex#GO:0043235;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000045100.1|UniProtKB=A0A5F8H553 A0A5F8H553 PTHR20981:SF6 60S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN EL21 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000048086.1|UniProtKB=A0A5F8GS10 A0A5F8GS10 NUDT3 PTHR12629:SF5 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 1 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;small molecule catabolic process#GO:0044282;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000046266.1|UniProtKB=A0A5F8H3J5 A0A5F8H3J5 NRIP3 PTHR12917:SF16 ASPARTYL PROTEASE DDI-RELATED NUCLEAR RECEPTOR-INTERACTING PROTEIN 3 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 aspartic protease#PC00053;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000017434.4|UniProtKB=F6ZV69 F6ZV69 PEX7 PTHR46027:SF1 PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR signal sequence receptor activity#GO:0005048 localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;peroxisomal transport#GO:0043574;protein transport#GO:0015031;peroxisome organization#GO:0007031;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 cytosol#GO:0005829;peroxisome#GO:0005777;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782 MONDO|Ensembl=ENSMODG00000014224.4|UniProtKB=F6T9I6 F6T9I6 DLGAP2 PTHR12353:SF3 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 2 regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 cell junction#GO:0030054;organelle#GO:0043226;postsynaptic specialization#GO:0099572;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014629.3|UniProtKB=A0A5F8G5I5 A0A5F8G5I5 GLG1 PTHR11884:SF1 SELECTIN LIGAND RELATED GOLGI APPARATUS PROTEIN 1 fibroblast growth factor binding#GO:0017134;growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000028376.2|UniProtKB=F7G1L0 F7G1L0 TREM1 PTHR19357:SF0 TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1 TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;leukocyte migration#GO:0050900;cell killing#GO:0001906;response to other organism#GO:0051707;cell migration#GO:0016477;cell chemotaxis#GO:0060326;chemotaxis#GO:0006935;response to bacterium#GO:0009617;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;cell motility#GO:0048870;cellular response to stimulus#GO:0051716;immune effector process#GO:0002252;neutrophil chemotaxis#GO:0030593;response to chemical#GO:0042221;neutrophil migration#GO:1990266;taxis#GO:0042330;granulocyte migration#GO:0097530;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;leukocyte mediated immunity#GO:0002443;defense response to bacterium#GO:0042742;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;leukocyte mediated cytotoxicity#GO:0001909 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 MONDO|Ensembl=ENSMODG00000015268.4|UniProtKB=F6TML0 F6TML0 GPC3 PTHR10822:SF4 GLYPICAN GLYPICAN-3 regulation of response to stimulus#GO:0048583;regulation of localization#GO:0032879;positive regulation of canonical Wnt signaling pathway#GO:0090263;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of protein localization to membrane#GO:1905475;positive regulation of biological process#GO:0048518;regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell migration#GO:0016477;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of protein localization#GO:0032880;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;cell motility#GO:0048870;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000015336.3|UniProtKB=F6XEU6 F6XEU6 PTHR26453:SF76 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13H1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000639.4|UniProtKB=F6SUU6 F6SUU6 MMP20 PTHR10201:SF125 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-20 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;anatomical structure formation involved in morphogenesis#GO:0048646;metabolic process#GO:0008152;developmental process#GO:0032502;odontogenesis of dentin-containing tooth#GO:0042475;amelogenesis#GO:0097186;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;catabolic process#GO:0009056;animal organ morphogenesis#GO:0009887;odontogenesis#GO:0042476;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 MONDO|Ensembl=ENSMODG00000006467.4|UniProtKB=K7E5Q0 K7E5Q0 KIF11 PTHR47970:SF26 KINESIN-LIKE PROTEIN KIF11 KINESIN-LIKE PROTEIN KIF11 catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;plus-end-directed microtubule motor activity#GO:0008574;microtubule motor activity#GO:0003777 organelle assembly#GO:0070925;nuclear division#GO:0000280;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;chromosome segregation#GO:0007059;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;spindle assembly#GO:0051225;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231 mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;spindle microtubule#GO:0005876;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;spindle#GO:0005819;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000050318.1|UniProtKB=A0A5F8GGS1 A0A5F8GGS1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000005049.3|UniProtKB=F7AT88 F7AT88 OSGIN1 PTHR15192:SF15 PROTEIN CBG05349 OXIDATIVE STRESS-INDUCED GROWTH INHIBITOR 1 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cell growth#GO:0030308;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of growth#GO:0040008 MONDO|Ensembl=ENSMODG00000009024.4|UniProtKB=F7B2Z2 F7B2Z2 ASCC2 PTHR21494:SF3 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 ASC-1 COMPLEX SUBUNIT P100 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 MONDO|Ensembl=ENSMODG00000021421.5|UniProtKB=F7CBH5 F7CBH5 SEH1L PTHR11024:SF3 NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER NUCLEOPORIN SEH1 response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;response to nutrient levels#GO:0031667;response to stress#GO:0006950;positive regulation of TORC1 signaling#GO:1904263;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;cellular response to amino acid starvation#GO:0034198;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular response to starvation#GO:0009267;positive regulation of intracellular signal transduction#GO:1902533;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;regulation of TORC1 signaling#GO:1903432 organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear pore outer ring#GO:0031080;nuclear protein-containing complex#GO:0140513;Seh1-associated complex#GO:0035859;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000045807.1|UniProtKB=K7DYT9 K7DYT9 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000001720.5|UniProtKB=F6XGB3 F6XGB3 KCNC4 PTHR11537:SF126 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL KCNC4 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;potassium ion transport#GO:0006813;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;action potential#GO:0001508 axon terminus#GO:0043679;neuron projection membrane#GO:0032589;voltage-gated potassium channel complex#GO:0008076;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;neuronal cell body#GO:0043025;neuron projection terminus#GO:0044306;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;transporter complex#GO:1990351;cation channel complex#GO:0034703;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;cell leading edge#GO:0031252;presynapse#GO:0098793;neuron projection#GO:0043005;cell projection membrane#GO:0031253;postsynaptic membrane#GO:0045211;leading edge membrane#GO:0031256;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;postsynapse#GO:0098794;cell body#GO:0044297 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000009225.4|UniProtKB=F7EE92 F7EE92 PTHR26452:SF828 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000558.4|UniProtKB=A0A5F8GG16 A0A5F8GG16 CEP126 PTHR31191:SF4 CENTROSOMAL PROTEIN CEP126 CENTROSOMAL PROTEIN OF 126 KDA cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;cytoplasmic microtubule organization#GO:0031122;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271 intracellular membraneless organelle#GO:0043232;ciliary base#GO:0097546;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;midbody#GO:0030496;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000024158.1|UniProtKB=F6WYP2 F6WYP2 GJB6 PTHR11984:SF23 CONNEXIN GAP JUNCTION BETA-6 PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 regulation of biological process#GO:0050789;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;transport#GO:0006810;cell communication#GO:0007154;localization#GO:0051179;establishment of localization#GO:0051234 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054 gap junction#PC00105;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000006913.4|UniProtKB=F6PT29 F6PT29 ASNA1 PTHR10803:SF3 ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE ATPASE GET3 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;protein localization to organelle#GO:0033365 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 MONDO|Ensembl=ENSMODG00000008148.3|UniProtKB=F7ELJ9 F7ELJ9 DACT1 PTHR15919:SF12 DAPPER-RELATED DAPPER HOMOLOG 1 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of JNK cascade#GO:0046328 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 Wnt signaling pathway#P00057>Frodo#P01470;Wnt signaling pathway#P00057>Dapper#P01469 MONDO|Ensembl=ENSMODG00000019619.3|UniProtKB=A0A5F8G318 A0A5F8G318 HTR1A PTHR24247:SF20 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1A G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;heterocyclic compound binding#GO:1901363;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;serotonin binding#GO:0051378;cation binding#GO:0043169;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;signaling#GO:0023052;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536 dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 MONDO|Ensembl=ENSMODG00000027763.2|UniProtKB=K7E155 K7E155 LOC100013176 PTHR10590:SF16 SODIUM/NUCLEOSIDE COTRANSPORTER SODIUM_NUCLEOSIDE COTRANSPORTER 1 symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505;monoatomic cation transmembrane transporter activity#GO:0008324;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;nucleoside transmembrane transporter activity#GO:0005337;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081 transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;nucleobase-containing compound transport#GO:0015931 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 MONDO|Ensembl=ENSMODG00000020703.4|UniProtKB=F7D1E1 F7D1E1 NOA1 PTHR46406:SF1 NITRIC OXIDE-ASSOCIATED PROTEIN 1 NITRIC OXIDE-ASSOCIATED PROTEIN 1 ribosomal small subunit biogenesis#GO:0042274;mitochondrial ribosome assembly#GO:0061668;protein-containing complex organization#GO:0043933;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component assembly#GO:0022607;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;protein-RNA complex assembly#GO:0022618;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;ribonucleoprotein complex biogenesis#GO:0022613 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000011027.4|UniProtKB=F7F4I1 F7F4I1 CALHM3 PTHR32261:SF7 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 3 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000001265.3|UniProtKB=F7CIZ3 F7CIZ3 PTHR48494:SF1 INTERLEUKIN-6 INTERLEUKIN-6 molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cell surface receptor signaling pathway#GO:0007166;defense response#GO:0006952;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;inflammatory response#GO:0006954;cell communication#GO:0007154;response to peptide#GO:1901652;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 Interleukin signaling pathway#P00036>Interleukin#P00970;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 MONDO|Ensembl=ENSMODG00000015677.4|UniProtKB=F7EHR1 F7EHR1 LXN PTHR28591:SF1 LATEXIN LATEXIN enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000018313.5|UniProtKB=F6UNV4 F6UNV4 PTHR14453:SF70 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP9 protein binding#GO:0005515;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;pentosyltransferase activity#GO:0016763;binding#GO:0005488;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;glycosyltransferase activity#GO:0016757;transcription corepressor activity#GO:0003714;transferase activity#GO:0016740;ubiquitin-like protein ligase binding#GO:0044389;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of cytokine-mediated signaling pathway#GO:0001961;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of response to cytokine stimulus#GO:0060759;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;regulation of cytokine-mediated signaling pathway#GO:0001959;positive regulation of signal transduction#GO:0009967;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of biosynthetic process#GO:0009890;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;positive regulation of response to biotic stimulus#GO:0002833;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000005361.4|UniProtKB=F6YL42 F6YL42 LOC100023173 PTHR24300:SF400 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C9 tetrapyrrole binding#GO:0046906;binding#GO:0005488;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037 unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;response to xenobiotic stimulus#GO:0009410;olefinic compound metabolic process#GO:0120254;xenobiotic metabolic process#GO:0006805;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000007248.3|UniProtKB=F6WBE5 F6WBE5 PTHR12419:SF21 OTU DOMAIN CONTAINING PROTEIN DEUBIQUITINASE OTUD6B hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000016655.4|UniProtKB=F6ZVH2 F6ZVH2 RGS11 PTHR45746:SF3 LP21163P REGULATOR OF G PROTEIN SIGNALING 11 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 G protein-coupled dopamine receptor signaling pathway#GO:0007212;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 MONDO|Ensembl=ENSMODG00000023033.3|UniProtKB=F6SIX0 F6SIX0 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000012301.4|UniProtKB=F7EJ76 F7EJ76 RBM5 PTHR13948:SF21 RNA-BINDING PROTEIN RNA-BINDING PROTEIN 5 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000020532.3|UniProtKB=F7ENG1 F7ENG1 TLR6 PTHR24365:SF557 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 1 molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor activity#GO:0038023;lipid binding#GO:0008289;binding#GO:0005488;signaling receptor binding#GO:0005102 immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;toll-like receptor signaling pathway#GO:0002224;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;regulation of response to external stimulus#GO:0032101;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cell communication#GO:0007154;response to bacterium#GO:0009617;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;response to external biotic stimulus#GO:0043207;cellular response to biotic stimulus#GO:0071216;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;cellular response to molecule of bacterial origin#GO:0071219;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009032.4|UniProtKB=F7B2K1 F7B2K1 PIP4K2A PTHR23086:SF21 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 ALPHA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 kinase#PC00137;transferase#PC00220 MONDO|Ensembl=ENSMODG00000037767.1|UniProtKB=A0A5F8HGF1 A0A5F8HGF1 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000018724.3|UniProtKB=F7EYM9 F7EYM9 BEND6 PTHR35346:SF1 BEN DOMAIN-CONTAINING PROTEIN 6 BEN DOMAIN-CONTAINING PROTEIN 6 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of neuron differentiation#GO:0045664;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;positive regulation of developmental process#GO:0051094;negative regulation of Notch signaling pathway#GO:0045746;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000016088.3|UniProtKB=F7FZ51 F7FZ51 PTHR15573:SF0 G-PROTEIN COUPLED RECEPTOR 160-RELATED G PROTEIN-COUPLED RECEPTOR 160-RELATED protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000042648.1|UniProtKB=A0A5F8HEV1 A0A5F8HEV1 RAB5C PTHR24073:SF366 DRAB5-RELATED RAS-RELATED PROTEIN RAB-5C hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 protein transport#GO:0015031;intracellular protein localization#GO:0008104;import into cell#GO:0098657;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;endocytosis#GO:0006897;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036 membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000045309.1|UniProtKB=A0A5F8H5C4 A0A5F8H5C4 PTHR11691:SF37 TYPE I INTERFERON INTERFERON OMEGA-1 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877 defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune response#GO:0006955;response to other organism#GO:0051707;adaptive immune response#GO:0002250;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell activation#GO:0001775;cytokine-mediated signaling pathway#GO:0019221;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;leukocyte activation involved in immune response#GO:0002366;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;natural killer cell activation#GO:0030101;humoral immune response#GO:0006959;B cell activation#GO:0042113;cellular process#GO:0009987;defense response to symbiont#GO:0140546;lymphocyte activation involved in immune response#GO:0002285;signal transduction#GO:0007165;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;T cell activation involved in immune response#GO:0002286;defense response to other organism#GO:0098542;lymphocyte activation#GO:0046649;response to cytokine#GO:0034097;response to chemical#GO:0042221;type I interferon-mediated signaling pathway#GO:0060337;B cell activation involved in immune response#GO:0002312;immune system process#GO:0002376;cell activation involved in immune response#GO:0002263;response to peptide#GO:1901652;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083;interferon superfamily#PC00127 MONDO|Ensembl=ENSMODG00000023647.3|UniProtKB=F7D9C6 F7D9C6 LOC103105149 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000023349.1|UniProtKB=F6TSG3 F6TSG3 GJB3 PTHR11984:SF65 CONNEXIN GAP JUNCTION BETA-3 PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 regulation of biological process#GO:0050789;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020 gap junction#PC00105;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000002805.4|UniProtKB=F7EJH2 F7EJH2 EIF2S2 PTHR23001:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 2 translation initiation factor binding#GO:0031369;translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051;protein binding#GO:0005515;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000010947.4|UniProtKB=F7EP10 F7EP10 GMEB1 PTHR10417:SF3 GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000013882.5|UniProtKB=F6TQJ0 F6TQJ0 CDH22 PTHR24027:SF311 CADHERIN-23 CADHERIN-22 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell-cell junction assembly#GO:0007043;cellular component assembly#GO:0022607;cell migration#GO:0016477;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;cell motility#GO:0048870;cell junction organization#GO:0034330;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000001490.4|UniProtKB=A0A5F8GJK3 A0A5F8GJK3 PTHR23280:SF24 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 1 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 Nicotine pharmacodynamics pathway#P06587>EPB41L1#P06599;Dopamine receptor mediated signaling pathway#P05912>EPB41L1#P05953;Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 MONDO|Ensembl=ENSMODG00000007249.4|UniProtKB=F6VWV4 F6VWV4 SMOC1 PTHR12352:SF13 SECRETED MODULAR CALCIUM-BINDING PROTEIN SPARC-RELATED MODULAR CALCIUM-BINDING PROTEIN 1 glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367;binding#GO:0005488;heparin binding#GO:0008201;extracellular matrix binding#GO:0050840 extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000040827.1|UniProtKB=A0A5F8H7W1 A0A5F8H7W1 DYNLT2 PTHR21255:SF27 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2 binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;dynein complex#GO:0030286;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000043165.1|UniProtKB=A0A5F8HJF2 A0A5F8HJF2 LOC100618508 PTHR48002:SF97 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005968.4|UniProtKB=F6W037 F6W037 PDE6B PTHR11347:SF73 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT BETA phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;visual system development#GO:0150063;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;negative regulation of signaling#GO:0023057;camera-type eye development#GO:0043010;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;anatomical structure development#GO:0048856;eye development#GO:0001654;negative regulation of cell communication#GO:0010648;system development#GO:0048731;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;retina development in camera-type eye#GO:0060041;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;sensory organ development#GO:0007423;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275 9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;cell projection membrane#GO:0031253;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730 hydrolase#PC00121;phosphodiesterase#PC00185 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PDEalphabeta#P00759 MONDO|Ensembl=ENSMODG00000017070.3|UniProtKB=F6XHB0 F6XHB0 NPBWR2 PTHR24229:SF18 NEUROPEPTIDES RECEPTOR NEUROPEPTIDES B_W RECEPTOR TYPE 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000023237.3|UniProtKB=A0A5F8G2V9 A0A5F8G2V9 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000021111.4|UniProtKB=F6U2W7 F6U2W7 XK PTHR14297:SF8 MEMBRANE TRANSPORT PROTEIN XK FAMILY MEMBER ENDOPLASMIC RETICULUM MEMBRANE ADAPTER PROTEIN XK molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000029268.2|UniProtKB=K7DZC5 K7DZC5 PDCD1 PTHR15264:SF2 PROGRAMMED CELL DEATH PROTEIN 1 PROGRAMMED CELL DEATH PROTEIN 1 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 MONDO|Ensembl=ENSMODG00000008343.4|UniProtKB=F7EKR3 F7EKR3 CNKSR3 PTHR12844:SF17 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor signaling pathway#GO:0007166 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017431.4|UniProtKB=F6ZVA0 F6ZVA0 SLC35D3 PTHR11132:SF515 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER D3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000029058.2|UniProtKB=K7DZJ4 K7DZJ4 LOC103097588 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000024090.2|UniProtKB=F7FVM6 F7FVM6 PRR15L PTHR14581:SF5 FAMILY NOT NAMED PROLINE-RICH PROTEIN 15-LIKE PROTEIN MONDO|Ensembl=ENSMODG00000001424.3|UniProtKB=F7BCQ6 F7BCQ6 PTHR23023:SF70 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000028243.2|UniProtKB=F6U4U4 F6U4U4 LOC100020270 PTHR24376:SF265 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 865 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000003631.5|UniProtKB=F7BMH8 F7BMH8 KCNV2 PTHR11537:SF40 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY V MEMBER 2 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459 metal ion transport#GO:0030001;action potential#GO:0001508;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 voltage-gated ion channel#PC00241;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000005636.4|UniProtKB=A0A5F8H2N4 A0A5F8H2N4 MAPK12 PTHR24055:SF146 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 12 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;p38 MAPK pathway#P05918>p38gamma#P06015;Ras Pathway#P04393>p38#P04558;Oxidative stress response#P00046>p38#P01135;B cell activation#P00010>p38#P00384;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;EGF receptor signaling pathway#P00018>p38#P00562;TGF-beta signaling pathway#P00052>P38#P01275;Parkinson disease#P00049>SAPK#P01219;FGF signaling pathway#P00021>p38#P00644;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Gonadotropin-releasing hormone receptor pathway#P06664>p38#P06831 MONDO|Ensembl=ENSMODG00000007140.3|UniProtKB=F6RZ59 F6RZ59 CPM PTHR11532:SF84 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE M peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 MONDO|Ensembl=ENSMODG00000019489.4|UniProtKB=F6WA27 F6WA27 TPX2 PTHR14326:SF67 TARGETING PROTEIN FOR XKLP2 TARGETING PROTEIN FOR XKLP2 kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 chromosome organization#GO:0051276;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;mitotic spindle assembly#GO:0090307;cellular process#GO:0009987;spindle assembly#GO:0051225;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;nuclear division#GO:0000280;organelle assembly#GO:0070925;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049 spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000016964.3|UniProtKB=F6V4W6 F6V4W6 SSR2 PTHR12861:SF3 TRANSLOCON-ASSOCIATED PROTEIN, BETA SUBUNIT PRECURSOR TRAP-BETA SIGNAL SEQUENCE RECEPTOR BETA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT BETA membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000017929.5|UniProtKB=F7EKA1 F7EKA1 SLC22A16 PTHR24064:SF186 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 16 quaternary ammonium group transmembrane transporter activity#GO:0015651;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000040003.1|UniProtKB=K7E3P6 K7E3P6 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000024407.2|UniProtKB=F6Z3N3 F6Z3N3 monDomV1R1258 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000039418.1|UniProtKB=A0A5F8GDG1 A0A5F8GDG1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000045602.1|UniProtKB=A0A5F8GBZ5 A0A5F8GBZ5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016167.4|UniProtKB=F7G8R6 F7G8R6 GCK PTHR19443:SF3 HEXOKINASE HEXOKINASE-4 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773 monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;pyruvate metabolic process#GO:0006090;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;regulation of signaling#GO:0023051;regulation of hormone secretion#GO:0046883;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;regulation of biological quality#GO:0065008;regulation of insulin secretion#GO:0050796;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ADP catabolic process#GO:0046032;purine nucleoside diphosphate catabolic process#GO:0009137;glucose homeostasis#GO:0042593;nucleobase-containing small molecule metabolic process#GO:0055086;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;regulation of protein secretion#GO:0050708;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate catabolic process#GO:1901292;regulation of cellular process#GO:0050794;nucleoside triphosphate metabolic process#GO:0009141;regulation of cell communication#GO:0010646;carbohydrate derivative catabolic process#GO:1901136;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;biological regulation#GO:0065007;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;ADP metabolic process#GO:0046031;cellular homeostasis#GO:0019725;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;ribonucleoside diphosphate metabolic process#GO:0009185;carbohydrate homeostasis#GO:0033500;regulation of hormone levels#GO:0010817;regulation of protein transport#GO:0051223;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;oxoacid metabolic process#GO:0043436;regulation of secretion by cell#GO:1903530;intracellular glucose homeostasis#GO:0001678;regulation of protein localization#GO:0032880;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;regulation of transport#GO:0051049;regulation of localization#GO:0032879;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;catabolic process#GO:0009056;glucose 6-phosphate metabolic process#GO:0051156;nucleoside phosphate metabolic process#GO:0006753;homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;regulation of secretion#GO:0051046;ribonucleoside diphosphate catabolic process#GO:0009191;regulation of establishment of protein localization#GO:0070201;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;intracellular chemical homeostasis#GO:0055082 outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;side of membrane#GO:0098552;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasmic side of membrane#GO:0098562;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000044855.1|UniProtKB=A0A5F8HF89 A0A5F8HF89 PTHR47499:SF2 SERINE PROTEASE INHIBITOR KAZAL-TYPE 7 SPINK7 SERINE PROTEASE INHIBITOR KAZAL-TYPE 9 peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000022885.1|UniProtKB=F6TJ97 F6TJ97 LOC100023950 PTHR26450:SF115 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025678.3|UniProtKB=F6U0R7 F6U0R7 PTHR19944:SF99 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ BETA 1 CHAIN protein-containing complex binding#GO:0044877;antigen binding#GO:0003823;peptide binding#GO:0042277;binding#GO:0005488 positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of cell adhesion#GO:0045785;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of T cell activation#GO:0050863;positive regulation of leukocyte activation#GO:0002696;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;regulation of lymphocyte activation#GO:0051249;immune system process#GO:0002376 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;late endosome#GO:0005770;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;vesicle membrane#GO:0012506;membrane#GO:0016020 major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000047487.1|UniProtKB=K7DYR6 K7DYR6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003387.4|UniProtKB=F6Z1M2 F6Z1M2 KANK1 PTHR24168:SF19 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1 negative regulation of cellular component organization#GO:0051129;cellular component organization#GO:0016043;negative regulation of organelle organization#GO:0010639;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;negative regulation of protein polymerization#GO:0032272;regulation of actin filament length#GO:0030832;negative regulation of cytoskeleton organization#GO:0051494;regulation of biological quality#GO:0065008;negative regulation of protein-containing complex assembly#GO:0031333;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000016683.3|UniProtKB=F7DMG8 F7DMG8 LRRC71 PTHR46984:SF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 71 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 71 MONDO|Ensembl=ENSMODG00000037671.1|UniProtKB=A0A5F8H7S1 A0A5F8H7S1 PTHR22625:SF61 PLEXIN HEPATOCYTE GROWTH FACTOR RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;synapse assembly#GO:0007416;cell junction organization#GO:0034330;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;regulation of cell migration#GO:0030334;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;regulation of locomotion#GO:0040012;biological regulation#GO:0065007 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011653.4|UniProtKB=A0A5F8GEF8 A0A5F8GEF8 TDP2 PTHR15822:SF28 TRAF AND TNF RECEPTOR-ASSOCIATED PROTEIN TYROSYL-DNA PHOSPHODIESTERASE 2 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA binding#GO:0003677;hydrolase activity#GO:0016787;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488 primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 membraneless organelle#GO:0043228;nuclear body#GO:0016604;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000021162.4|UniProtKB=F6XXE3 F6XXE3 PTHR45620:SF19 PDF RECEPTOR-LIKE PROTEIN-RELATED CORTICOTROPIN-RELEASING HORMONE RECEPTOR 2 molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;binding#GO:0005488;signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;hormone binding#GO:0042562 regulation of signaling#GO:0023051;positive regulation of synaptic transmission#GO:0050806;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of synaptic plasticity#GO:0048167;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 cell periphery#GO:0071944;neuron projection#GO:0043005;presynapse#GO:0098793;membrane#GO:0016020;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;axon terminus#GO:0043679;cell junction#GO:0030054;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;neuron projection terminus#GO:0044306;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425 transmembrane signal receptor#PC00197 Cortocotropin releasing factor receptor signaling pathway#P04380>CRHR1#P04451 MONDO|Ensembl=ENSMODG00000029682.2|UniProtKB=K7DZM5 K7DZM5 PTHR22748:SF23 AP ENDONUCLEASE EXODEOXYRIBONUCLEASE III 3'-5' exonuclease activity#GO:0008408;phosphoric diester hydrolase activity#GO:0008081;catalytic activity, acting on DNA#GO:0140097;phosphoric ester hydrolase activity#GO:0042578;DNA exonuclease activity#GO:0004529;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;DNA endonuclease activity#GO:0004520;exonuclease activity#GO:0004527;endonuclease activity#GO:0004519;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000020820.3|UniProtKB=F6RM72 F6RM72 PTHR12035:SF125 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 5 organic acid binding#GO:0043177;ion binding#GO:0043167;carbohydrate derivative binding#GO:0097367;binding#GO:0005488;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;anion binding#GO:0043168 cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000010480.5|UniProtKB=F7ESJ6 F7ESJ6 PRPF8 PTHR11140:SF0 PRE-MRNA SPLICING FACTOR PRP8 PRE-MRNA-PROCESSING-SPLICING FACTOR 8 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000039023.1|UniProtKB=A0A5F8H145 A0A5F8H145 PTHR28654:SF1 AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;determination of bilateral symmetry#GO:0009855;negative regulation of signal transduction#GO:0009968;regulation of protein metabolic process#GO:0051246;multicellular organism development#GO:0007275;regulation of JNK cascade#GO:0046328;regulation of MAPK cascade#GO:0043408;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;regulation of cell communication#GO:0010646;negative regulation of MAPK cascade#GO:0043409;dorsal/ventral pattern formation#GO:0009953;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;negative regulation of response to stimulus#GO:0048585;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein modification process#GO:0031399;negative regulation of cellular process#GO:0048523;specification of symmetry#GO:0009799;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000041817.1|UniProtKB=A0A5F8HIJ1 A0A5F8HIJ1 PTHR21577:SF3 SHUGOSHIN SHUGOSHIN 2 organelle fission#GO:0048285;sister chromatid cohesion#GO:0007062;sexual reproduction#GO:0019953;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;cell cycle process#GO:0022402;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cell cycle#GO:0007049;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;meiotic sister chromatid cohesion#GO:0051177;meiotic nuclear division#GO:0140013;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;mitotic sister chromatid cohesion#GO:0007064;cellular process#GO:0009987;organelle organization#GO:0006996 chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 centromere DNA-binding protein#PC00071 MONDO|Ensembl=ENSMODG00000006520.3|UniProtKB=F7E3Z0 F7E3Z0 KCNS2 PTHR11537:SF60 VOLTAGE-GATED POTASSIUM CHANNEL DELAYED-RECTIFIER POTASSIUM CHANNEL REGULATORY SUBUNIT KCNS2 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459 monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transport#GO:0006813;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;metal ion transport#GO:0030001;action potential#GO:0001508;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000040347.1|UniProtKB=A0A5F8GCC0 A0A5F8GCC0 monDomV1R1271 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000047655.1|UniProtKB=A0A5F8HLY2 A0A5F8HLY2 MRPS23 PTHR15925:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S23 SMALL RIBOSOMAL SUBUNIT PROTEIN MS23 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000012101.3|UniProtKB=F7FUH7 F7FUH7 RGS2 PTHR10845:SF43 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 2 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of biological process#GO:0050789 cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 GTPase-activating protein#PC00257 CCKR signaling map#P06959>RGS2#P07040;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 MONDO|Ensembl=ENSMODG00000012043.4|UniProtKB=F7ALI5 F7ALI5 MIPOL1 PTHR22089:SF2 MIRROR-IMAGE POLYDACTYLY GENE 1 PROTEIN MIRROR-IMAGE POLYDACTYLY GENE 1 PROTEIN MONDO|Ensembl=ENSMODG00000014903.4|UniProtKB=A0A5F8G8X0 A0A5F8G8X0 THRB PTHR24082:SF210 NUCLEAR HORMONE RECEPTOR THYROID HORMONE RECEPTOR BETA transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;hormone-mediated signaling pathway#GO:0009755;negative regulation of DNA-templated transcription#GO:0045892;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;response to hormone#GO:0009725;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;intracellular receptor signaling pathway#GO:0030522;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513 C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000024846.1|UniProtKB=F7EBX2 F7EBX2 PHLDA3 PTHR15478:SF5 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, PQ-RICH PROTEIN PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY A MEMBER 3 regulation of biological process#GO:0050789;apoptotic process#GO:0006915;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;signaling#GO:0023052;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;signal transduction by p53 class mediator#GO:0072331;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;intrinsic apoptotic signaling pathway#GO:0097193;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;negative regulation of signal transduction#GO:0009968;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;DNA damage response#GO:0006974;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;apoptotic signaling pathway#GO:0097190 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000038830.1|UniProtKB=A0A5F8G426 A0A5F8G426 PTHR10424:SF82 VIRAL ENVELOPE PROTEIN ENVELOPE POLYPROTEIN myoblast fusion#GO:0007520;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;cell differentiation#GO:0030154;muscle structure development#GO:0061061;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;syncytium formation by cell-cell fusion#GO:0000768;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;striated muscle cell differentiation#GO:0051146 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000023914.2|UniProtKB=F7FYA6 F7FYA6 ARF6 PTHR11711:SF480 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 6 guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;regulation of biological process#GO:0050789;protein localization to organelle#GO:0033365;regulation of developmental process#GO:0050793;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031 recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;ruffle#GO:0001726;recycling endosome#GO:0055037;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf6#P00919 MONDO|Ensembl=ENSMODG00000002057.3|UniProtKB=F6V051 F6V051 HMGCR PTHR10572:SF24 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 cellular process#GO:0009987;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;metabolic process#GO:0008152;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;isoprenoid metabolic process#GO:0006720 peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;peroxisomal membrane#GO:0005778;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 reductase#PC00198 Cholesterol biosynthesis#P00014>Hydroxymethyl glutaryl CoA reductase#P00491 MONDO|Ensembl=ENSMODG00000049490.1|UniProtKB=K7E1B4 K7E1B4 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000010506.2|UniProtKB=A0A5F8G6C4 A0A5F8G6C4 IDO2 PTHR28657:SF4 INDOLEAMINE 2,3-DIOXYGENASE INDOLEAMINE 2,3-DIOXYGENASE 2 catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;oxoacid metabolic process#GO:0043436;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;indole-containing compound metabolic process#GO:0042430;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;carboxylic acid catabolic process#GO:0046395;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000037737.1|UniProtKB=A0A5F8GCZ8 A0A5F8GCZ8 LOC100618138 PTHR48018:SF47 OLFACTORY RECEPTOR OLFACTORY RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012399.4|UniProtKB=A0A5F8GMV2 A0A5F8GMV2 FBXO15 PTHR46731:SF1 F-BOX ONLY PROTEIN 15 F-BOX ONLY PROTEIN 15 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535 MONDO|Ensembl=ENSMODG00000010098.4|UniProtKB=F6X568 F6X568 ACBD7 PTHR23310:SF51 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 7 ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;lipid binding#GO:0008289;heterocyclic compound binding#GO:1901363 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000037610.1|UniProtKB=A0A5F8HJU6 A0A5F8HJU6 RNF146 PTHR13417:SF2 E3 UBIQUITIN-PROTEIN LIGASE RNF146 E3 UBIQUITIN-PROTEIN LIGASE RNF146 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000010177.4|UniProtKB=F6TA03 F6TA03 SESTD1 PTHR46607:SF1 SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1 SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1 phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;phospholipid binding#GO:0005543 MONDO|Ensembl=ENSMODG00000016361.4|UniProtKB=F7F6S4 F7F6S4 DUS4L PTHR11082:SF31 TRNA-DIHYDROURIDINE SYNTHASE TRNA-DIHYDROURIDINE(20A_20B) SYNTHASE [NAD(P)+]-LIKE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000040814.1|UniProtKB=A0A5F8HEN8 A0A5F8HEN8 PTHR26452:SF52 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018818.4|UniProtKB=F6YZB4 F6YZB4 TRAM2 PTHR12371:SF4 TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN 2 protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000046505.1|UniProtKB=A0A5F8HHA8 A0A5F8HHA8 GPR173 PTHR19268:SF4 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 173-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015030.4|UniProtKB=A0A5F8GSS8 A0A5F8GSS8 SLC4A7 PTHR11453:SF105 ANION EXCHANGE PROTEIN SODIUM BICARBONATE COTRANSPORTER 3 active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;bicarbonate transmembrane transporter activity#GO:0015106;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293 nervous system development#GO:0007399;hair cell differentiation#GO:0035315;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;animal organ development#GO:0048513;multicellular organism development#GO:0007275;chemical homeostasis#GO:0048878;neuron differentiation#GO:0030182;cell differentiation#GO:0030154;cell development#GO:0048468;intracellular monoatomic ion homeostasis#GO:0006873;transmembrane transport#GO:0055085;neuron development#GO:0048666;regulation of biological quality#GO:0065008;ear development#GO:0043583;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;biological regulation#GO:0065007;inner ear development#GO:0048839;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;neurogenesis#GO:0022008;intracellular chemical homeostasis#GO:0055082;epidermis development#GO:0008544;sensory organ development#GO:0007423;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;developmental process#GO:0032502;homeostatic process#GO:0042592;anatomical structure development#GO:0048856;localization#GO:0051179;system development#GO:0048731;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basal part of cell#GO:0045178;apical plasma membrane#GO:0016324;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;apical part of cell#GO:0045177 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000011917.3|UniProtKB=F7E008 F7E008 ASTE1 PTHR15665:SF1 ASTEROID PROTEIN SINGLE-STRAND DNA ENDONUCLEASE ASTE1 MONDO|Ensembl=ENSMODG00000014789.4|UniProtKB=F7G6S0 F7G6S0 EFHB PTHR12086:SF12 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING FAMILY MEMBER B molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 regulation of cellular process#GO:0050794;cell motility#GO:0048870;microtubule-based movement#GO:0007018;regulation of metal ion transport#GO:0010959;regulation of cell communication#GO:0010646;reproductive process#GO:0022414;regulation of calcium-mediated signaling#GO:0050848;sperm motility#GO:0097722;regulation of biological process#GO:0050789;cilium-dependent cell motility#GO:0060285;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of signal transduction#GO:0009966;regulation of calcineurin-NFAT signaling cascade#GO:0070884;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;microtubule-based process#GO:0007017;regulation of localization#GO:0032879;regulation of transport#GO:0051049;flagellated sperm motility#GO:0030317;regulation of response to stimulus#GO:0048583 cytoplasmic microtubule#GO:0005881;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;cilium#GO:0005929;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000048898.1|UniProtKB=A0A5F8H3U7 A0A5F8H3U7 PTHR10496:SF7 40S RIBOSOMAL PROTEIN S24 SMALL RIBOSOMAL SUBUNIT PROTEIN ES24 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000047572.1|UniProtKB=A0A5F8GBH9 A0A5F8GBH9 PTHR10666:SF523 UBIQUITIN UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;nucleus#GO:0005634;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000019523.4|UniProtKB=A0A5F8GW01 A0A5F8GW01 PTHR24054:SF16 CASEIN KINASE II SUBUNIT ALPHA CASEIN KINASE II SUBUNIT ALPHA-RELATED protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459 MONDO|Ensembl=ENSMODG00000025356.2|UniProtKB=F7E5N0 F7E5N0 PTHR10769:SF3 40S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN ES28 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000029357.2|UniProtKB=K7E677 K7E677 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009817.4|UniProtKB=A0A5F8HEW6 A0A5F8HEW6 STRADA PTHR48014:SF20 SERINE/THREONINE-PROTEIN KINASE FRAY2 STE20-RELATED KINASE ADAPTER PROTEIN ALPHA molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539 nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein export from nucleus#GO:0006611;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000047488.1|UniProtKB=A0A5F8HJN8 A0A5F8HJN8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000012395.4|UniProtKB=F6PN87 F6PN87 PTHR14115:SF0 AMELOBLASTIN AMELOBLASTIN signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083 cell adhesion#GO:0007155;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000024306.2|UniProtKB=F7EI08 F7EI08 PTHR48018:SF91 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8U1-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048800.1|UniProtKB=A0A5F8HB55 A0A5F8HB55 RHEB PTHR24070:SF264 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN RHEB pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;protein kinase activator activity#GO:0030295;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;kinase activator activity#GO:0019209;hydrolase activity#GO:0016787;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;hydrolase activity, acting on acid anhydrides#GO:0016817;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of TORC1 signaling#GO:1904263;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of TORC1 signaling#GO:1903432;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;intracellular signal transduction#GO:0035556;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 CCKR signaling map#P06959>RHEB-GTP#P07224;CCKR signaling map#P06959>RHEB-GDP#P07175;p53 pathway by glucose deprivation#P04397>Rheb#P04642 MONDO|Ensembl=ENSMODG00000017935.4|UniProtKB=A0A5F8GTQ9 A0A5F8GTQ9 PLA2G4D PTHR10728:SF31 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 DELTA A2-type glycerophospholipase activity#GO:0004623;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;metal ion binding#GO:0046872;lipid binding#GO:0008289;binding#GO:0005488;calcium ion binding#GO:0005509;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689 lipid metabolic process#GO:0006629;glycerolipid catabolic process#GO:0046503;metabolic process#GO:0008152;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475;cellular process#GO:0009987;lipid catabolic process#GO:0016042;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;glycerophospholipid metabolic process#GO:0006650 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 phospholipase#PC00186 Angiogenesis#P00005>cPLA2#P00251 MONDO|Ensembl=ENSMODG00000023723.2|UniProtKB=F6UDH3 F6UDH3 PTHR23117:SF13 GUANYLATE KINASE-RELATED GUANYLATE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;phosphotransferase activity, phosphate group as acceptor#GO:0016776 ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137;transferase#PC00220 De novo purine biosynthesis#P02738>Guanylate kinase#P02904 MONDO|Ensembl=ENSMODG00000047546.1|UniProtKB=A0A5F8HBU7 A0A5F8HBU7 RASL11B PTHR45704:SF6 RAS-LIKE FAMILY MEMBER 11 RAS-LIKE PROTEIN FAMILY MEMBER 11B MONDO|Ensembl=ENSMODG00000044375.1|UniProtKB=A0A5F8H1I1 A0A5F8H1I1 PTHR23262:SF28 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 9-1-LIKE structural protein#PC00211 MONDO|Ensembl=ENSMODG00000046016.1|UniProtKB=A0A5F8GFX1 A0A5F8GFX1 PTHR10424:SF82 VIRAL ENVELOPE PROTEIN ENVELOPE POLYPROTEIN cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;syncytium formation by cell-cell fusion#GO:0000768;striated muscle cell differentiation#GO:0051146;animal gross anatomical part developmental process#GO:0160108;cell-cell fusion#GO:0140253;developmental process#GO:0032502;muscle structure development#GO:0061061;cell differentiation#GO:0030154;myoblast fusion#GO:0007520;cellular process#GO:0009987;muscle cell differentiation#GO:0042692 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000038536.1|UniProtKB=A0A5F8G917 A0A5F8G917 TIMP3 PTHR11844:SF22 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 3 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135 regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;response to hormone#GO:0009725;negative regulation of macromolecule metabolic process#GO:0010605;response to chemical#GO:0042221;negative regulation of protein catabolic process#GO:0042177;response to cytokine#GO:0034097;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162;regulation of catabolic process#GO:0009894;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176;response to peptide#GO:1901652 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000005847.4|UniProtKB=F6TL25 F6TL25 ENPEP PTHR11533:SF276 PROTEASE M1 ZINC METALLOPROTEASE GLUTAMYL AMINOPEPTIDASE peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237 regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;catabolic process#GO:0009056;circulatory system process#GO:0003013;proteolysis#GO:0006508;regulation of biological quality#GO:0065008;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;protein processing#GO:0016485;peptide hormone processing#GO:0016486;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;peptide catabolic process#GO:0043171;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;hormone metabolic process#GO:0042445;blood circulation#GO:0008015;metabolic process#GO:0008152;system process#GO:0003008;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000012560.4|UniProtKB=A0A5F8GKJ3 A0A5F8GKJ3 MRPL45 PTHR28554:SF1 39S RIBOSOMAL PROTEIN L45, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML45 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000000388.4|UniProtKB=F6R8E8 F6R8E8 ZCCHC4 PTHR13493:SF3 ZINC FINGER CCHC DOMAIN-CONTAINING RRNA N(6)-ADENOSINE-METHYLTRANSFERASE ZCCHC4 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a rRNA#GO:0140102;rRNA (adenine) methyltransferase activity#GO:0016433 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA methylation#GO:0031167;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;methylation#GO:0032259;rRNA processing#GO:0006364 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000003687.4|UniProtKB=F7FAI8 F7FAI8 MFSD14A PTHR23504:SF77 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 SOLUTE CARRIER FAMILY 71 MEMBER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 developmental process involved in reproduction#GO:0003006;multicellular organismal process#GO:0032501;male gamete generation#GO:0048232;gamete generation#GO:0007276;reproductive process#GO:0022414;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;system process#GO:0003008;multicellular organismal reproductive process#GO:0048609 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000050882.1|UniProtKB=H9H826 H9H826 LOC100025312 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000045758.1|UniProtKB=A0A5F8GWF4 A0A5F8GWF4 PLD6 PTHR43856:SF3 CARDIOLIPIN HYDROLASE MITOCHONDRIAL CARDIOLIPIN HYDROLASE phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;lipase activity#GO:0016298 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;nucleobase-containing compound biosynthetic process#GO:0034654;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;gene expression#GO:0010467;oogenesis#GO:0048477;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;germ cell development#GO:0007281;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulatory ncRNA-mediated gene silencing#GO:0031047;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605 mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000021211.4|UniProtKB=F6UH13 F6UH13 COL4A3 PTHR24023:SF1077 COLLAGEN ALPHA COLLAGEN ALPHA-3(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000015371.4|UniProtKB=F6WH69 F6WH69 LOC100016989 PTHR11769:SF9 HYALURONIDASE HYALURONIDASE catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;glycosaminoglycan catabolic process#GO:0006027 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000017542.3|UniProtKB=F7E1E1 F7E1E1 FOXG1 PTHR46617:SF3 FORKHEAD BOX PROTEIN G1 FORKHEAD BOX PROTEIN G1 binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000040198.1|UniProtKB=A0A5F8GDF0 A0A5F8GDF0 FLVCR2 PTHR10924:SF3 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED CHOLINE_ETHANOLAMINE TRANSPORTER FLVCR2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;heme binding#GO:0020037;binding#GO:0005488;tetrapyrrole binding#GO:0046906 nitrogen compound transport#GO:0071705;metal ion transport#GO:0030001;iron coordination entity transport#GO:1901678;iron ion transport#GO:0006826;transport#GO:0006810;transition metal ion transport#GO:0000041;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000018006.3|UniProtKB=F7AL60 F7AL60 GDF3 PTHR11848:SF38 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 3 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000005607.3|UniProtKB=F7CZU6 F7CZU6 DLL1 PTHR24044:SF380 NOTCH LIGAND FAMILY MEMBER DELTA-LIKE PROTEIN 1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 Notch signaling pathway#GO:0007219;negative regulation of Notch signaling pathway#GO:0045746;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Delta#P01116;Angiogenesis#P00005>Delta/Serrate#P00226 MONDO|Ensembl=ENSMODG00000009852.4|UniProtKB=F6WA87 F6WA87 NHLRC2 PTHR46388:SF2 NHL REPEAT-CONTAINING PROTEIN 2 NHL REPEAT-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000013111.4|UniProtKB=A0A5F8GGS3 A0A5F8GGS3 CYLD PTHR11830:SF15 40S RIBOSOMAL PROTEIN S3A UBIQUITIN CARBOXYL-TERMINAL HYDROLASE CYLD peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;structural molecule activity#GO:0005198;catalytic activity, acting on a protein#GO:0140096;structural constituent of ribosome#GO:0003735;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 cell death#GO:0008219;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of biological process#GO:0050789;protein modification process#GO:0036211;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;protein biosynthetic process#GO:0160307;regulation of cellular process#GO:0050794;translation#GO:0006412;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;necroptotic process#GO:0070266;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of signal transduction#GO:0009966;gene expression#GO:0010467;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000012322.4|UniProtKB=A0A5F8H6H2 A0A5F8H6H2 ANKRD27 PTHR24170:SF2 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;endocytic recycling#GO:0032456;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neuron development#GO:0048666;cellular localization#GO:0051641;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;endosomal transport#GO:0016197;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;localization within membrane#GO:0051668;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;early endosome to late endosome transport#GO:0045022;neurogenesis#GO:0022008;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;neuron projection morphogenesis#GO:0048812;transport#GO:0006810;developmental process#GO:0032502;intracellular transport#GO:0046907 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;late endosome#GO:0005770;transport vesicle#GO:0030133 MONDO|Ensembl=ENSMODG00000038001.1|UniProtKB=K7E1G1 K7E1G1 PTHR46890:SF56 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED OS06G0484800 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010312.4|UniProtKB=A0A5F8GL53 A0A5F8GL53 RANBP1 PTHR23138:SF94 RAN BINDING PROTEIN RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;nuclear transport#GO:0051169;nuclear export#GO:0051168;intracellular transport#GO:0046907;transport#GO:0006810;nucleocytoplasmic transport#GO:0006913 organelle envelope#GO:0031967;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000039577.1|UniProtKB=A0A5F8H2N3 A0A5F8H2N3 PTHR11799:SF16 PARAOXONASE SERUM PARAOXONASE_ARYLESTERASE 1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000002245.3|UniProtKB=A0A5F8GW78 A0A5F8GW78 PTHR24103:SF312 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 75 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 defense response#GO:0006952;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;response to other organism#GO:0051707;biological regulation#GO:0065007;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;response to biotic stimulus#GO:0009607;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000006032.4|UniProtKB=F6ZV05 F6ZV05 RALGPS2 PTHR23113:SF357 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR RALGPS2 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000005931.3|UniProtKB=F6WWP5 F6WWP5 NAA20 PTHR45910:SF1 N-ALPHA-ACETYLTRANSFERASE 20 N-ALPHA-ACETYLTRANSFERASE 20 catalytic activity#GO:0003824;transferase activity#GO:0016740;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186 regulation of actin filament-based process#GO:0032970;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000023144.2|UniProtKB=A0A5F8GN60 A0A5F8GN60 LOC103094087 PTHR31156:SF14 WBSCR19-LIKE PROTEIN SPEEDY_RINGO CELL CYCLE REGULATOR FAMILY, MEMBER E4C MONDO|Ensembl=ENSMODG00000013308.4|UniProtKB=F6YWC5 F6YWC5 MAP4K1 PTHR48012:SF15 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>GCK#P00268;Apoptosis signaling pathway#P00006>GCKR#P00311;Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861 MONDO|Ensembl=ENSMODG00000041585.1|UniProtKB=A0A5F8H569 A0A5F8H569 TNFSF10 PTHR11471:SF27 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 10 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125 positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;cell communication#GO:0007154;regulation of apoptotic signaling pathway#GO:2001233;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;regulation of extrinsic apoptotic signaling pathway#GO:2001236;positive regulation of signal transduction#GO:0009967;positive regulation of apoptotic process#GO:0043065;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Apoptosis signaling pathway#P00006>TRAIL#P00263 MONDO|Ensembl=ENSMODG00000016985.3|UniProtKB=A0A5F8H0N8 A0A5F8H0N8 PTHR23411:SF35 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT MU protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;antigen binding#GO:0003823 antibacterial humoral response#GO:0019731;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;immune effector process#GO:0002252;defense response to other organism#GO:0098542;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955;complement activation#GO:0006956;response to bacterium#GO:0009617;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000041428.1|UniProtKB=A0A5F8GMT8 A0A5F8GMT8 RASD1 PTHR46149:SF4 MIP08469P DEXAMETHASONE-INDUCED RAS-RELATED PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000037670.1|UniProtKB=A0A5F8HAN3 A0A5F8HAN3 C16orf90 PTHR37334:SF1 RGD1561796 SIMILAR TO HUMAN CHROMOSOME 16 OPEN READING FRAME 90 MONDO|Ensembl=ENSMODG00000038299.1|UniProtKB=A0A5F8G1Y1 A0A5F8G1Y1 PTHR23428:SF390 HISTONE H2B HISTONE H2B TYPE 1-O immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;antibacterial humoral response#GO:0019731;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000007859.4|UniProtKB=F6Y0N5 F6Y0N5 ZNF438 PTHR24408:SF23 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 438 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000044909.1|UniProtKB=A0A5F8GW92 A0A5F8GW92 RAB32 PTHR24073:SF1252 DRAB5-RELATED RAS-RELATED PROTEIN RAB-32 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 intracellular transport#GO:0046907;developmental process#GO:0032502;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;intracellular protein localization#GO:0008104;response to external stimulus#GO:0009605;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;developmental pigmentation#GO:0048066;developmental maturation#GO:0021700;cellular pigmentation#GO:0033059;pigmentation#GO:0043473;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell differentiation#GO:0030154 Golgi apparatus#GO:0005794;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;melanosome#GO:0042470;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;mitochondrion#GO:0005739 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000047631.1|UniProtKB=A0A5F8G3C4 A0A5F8G3C4 PTHR26450:SF164 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51B2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037452.1|UniProtKB=A0A5F8HCQ3 A0A5F8HCQ3 PTHR21695:SF0 ZINC FINGER PROTEIN 414 ZINC FINGER PROTEIN 414 MONDO|Ensembl=ENSMODG00000025584.3|UniProtKB=F6U2G5 F6U2G5 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006114.4|UniProtKB=F7EIE5 F7EIE5 PSEN2 PTHR10202:SF24 PRESENILIN PRESENILIN-2 aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 calcium ion homeostasis#GO:0055074;proteolysis#GO:0006508;inorganic ion homeostasis#GO:0098771;protein metabolic process#GO:0019538;cell communication#GO:0007154;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;homeostatic process#GO:0042592;signaling#GO:0023052;metabolic process#GO:0008152;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cell surface receptor signaling pathway#GO:0007166;Notch signaling pathway#GO:0007219;macromolecule metabolic process#GO:0043170;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;protein maturation#GO:0051604;gene expression#GO:0010467;membrane protein ectodomain proteolysis#GO:0006509;biological regulation#GO:0065007;biosynthetic process#GO:0009058 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 protease#PC00190;aspartic protease#PC00053 Alzheimer disease-presenilin pathway#P00004>Presenilin N-terminal fragment#P00140;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin C-terminal fragment#P00102;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin#P00098;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin N-terminal fragment#P00088;Alzheimer disease-presenilin pathway#P00004>Presenilin C-terminal fragment#P00155;Notch signaling pathway#P00045>Pen-2#P01113;Alzheimer disease-presenilin pathway#P00004>Presenilin#P00129 MONDO|Ensembl=ENSMODG00000009796.4|UniProtKB=A0A5F8GN83 A0A5F8GN83 OSBPL6 PTHR10972:SF76 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 6 sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094;steroid binding#GO:0005496;cholesterol binding#GO:0015485;lipid binding#GO:0008289;alcohol binding#GO:0043178 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;plasma membrane#GO:0005886;nuclear envelope#GO:0005635;perinuclear region of cytoplasm#GO:0048471;endomembrane system#GO:0012505;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;organelle membrane#GO:0031090;nuclear membrane#GO:0031965;endoplasmic reticulum#GO:0005783 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000047114.1|UniProtKB=A0A5F8GF62 A0A5F8GF62 LOC130455203 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000043171.1|UniProtKB=A0A5F8GKI2 A0A5F8GKI2 PTHR46041:SF2 MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2 MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;peptidase complex#GO:1905368;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;organelle membrane#GO:0031090;endopeptidase complex#GO:1905369;inner mitochondrial membrane protein complex#GO:0098800 protease#PC00190 MONDO|Ensembl=ENSMODG00000018921.4|UniProtKB=A0A5F8G9D9 A0A5F8G9D9 SUPT3H PTHR11380:SF16 TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED TRANSCRIPTION INITIATION PROTEIN SPT3 HOMOLOG transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;DNA-templated transcription#GO:0006351;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000000950.4|UniProtKB=F7F7P0 F7F7P0 CHAF1A PTHR15272:SF0 CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A CAF-1 SUBUNIT A CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597 protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;protein-DNA complex assembly#GO:0065004;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000038460.1|UniProtKB=A0A5F8HJH6 A0A5F8HJH6 ZDHHC4 PTHR22883:SF466 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC4 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein targeting#GO:0006605 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000004495.4|UniProtKB=F6VQP7 F6VQP7 ITPR1 PTHR13715:SF52 RYANODINE RECEPTOR AND IP3 RECEPTOR INOSITOL 1,4,5-TRISPHOSPHATE-GATED CALCIUM CHANNEL ITPR1 anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;cation binding#GO:0043169;phosphatidylinositol binding#GO:0035091;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;binding#GO:0005488;gated channel activity#GO:0022836;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated calcium channel activity#GO:0099604;calcium ion transmembrane transporter activity#GO:0015085;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;alcohol binding#GO:0043178 monoatomic ion transport#GO:0006811;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186;metal ion transport#GO:0030001;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;calcium ion transmembrane transport#GO:0070588;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;signal transduction#GO:0007165;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209 vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;sarcoplasm#GO:0016528;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;sarcoplasmic reticulum#GO:0016529;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 ligand-gated ion channel#PC00141;ion channel#PC00133 Histamine H1 receptor mediated signaling pathway#P04385>IP3R#P04486;Metabotropic glutamate receptor group I pathway#P00041>IP3R#P01056;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IP3R#P00842;Endothelin signaling pathway#P00019>IP3 R#P00590;Alpha adrenergic receptor signaling pathway#P00002>IP3R#P00076;B cell activation#P00010>IP3R#P00398;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>IP3 channel#P00735;PDGF signaling pathway#P00047>IP3 receptor#P01160;Gonadotropin-releasing hormone receptor pathway#P06664>IP3R#P06768;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>IP3R#P05932;Wnt signaling pathway#P00057>IP3 Gated Calcium Channel#P01426;T cell activation#P00053>IP3R#P01331;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>IP3R#P01064;CCKR signaling map#P06959>IP3R#P07123 MONDO|Ensembl=ENSMODG00000014379.3|UniProtKB=F6PYN9 F6PYN9 LOC100018560 PTHR10662:SF22 NUCLEAR RNA EXPORT FACTOR NUCLEAR RNA EXPORT FACTOR 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;biosynthetic process#GO:0009058;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000011528.3|UniProtKB=F6RHM1 F6RHM1 SNRPG PTHR10553:SF2 SMALL NUCLEAR RIBONUCLEOPROTEIN SMALL NUCLEAR RIBONUCLEOPROTEIN G binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;U1 snRNP#GO:0005685;ribonucleoprotein granule#GO:0035770;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;U12-type spliceosomal complex#GO:0005689;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231;U2-type prespliceosome#GO:0071004;cytoplasmic ribonucleoprotein granule#GO:0036464;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;precatalytic spliceosome#GO:0071011;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;U2 snRNP#GO:0005686;P granule#GO:0043186;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;spliceosomal complex#GO:0005681;U2-type spliceosomal complex#GO:0005684;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;SMN-Sm protein complex#GO:0034719 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000002691.4|UniProtKB=F7CYD5 F7CYD5 PTHR24257:SF10 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER ELASTASE-1 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000046496.1|UniProtKB=A0A5F8GP01 A0A5F8GP01 PTHR37868:SF1 TRANSMEMBRANE PROTEIN 190 TRANSMEMBRANE PROTEIN 190 cell development#GO:0048468;hemopoiesis#GO:0030097;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;developmental process#GO:0032502 intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;acrosomal membrane#GO:0002080;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 MONDO|Ensembl=ENSMODG00000012337.4|UniProtKB=F7E2E4 F7E2E4 IL17RD PTHR15583:SF14 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR D transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to cytokine#GO:0034097;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005223.2|UniProtKB=F6ZD21 F6ZD21 LOC100027866 PTHR22691:SF8 YEAST SPT2-RELATED PROTEIN SPT2 HOMOLOG DNA binding#GO:0003677;protein binding#GO:0005515;nucleic acid binding#GO:0003676;binding#GO:0005488;histone binding#GO:0042393 nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;transcription by RNA polymerase I#GO:0006360;protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;chromatin remodeling#GO:0006338;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000009153.3|UniProtKB=F7B0M2 F7B0M2 SLC6A5 PTHR11616:SF241 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 2 neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;glycine transmembrane transporter activity#GO:0015187;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324 carboxylic acid transmembrane transport#GO:1905039;signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;monoatomic ion transport#GO:0006811;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;glycine transport#GO:0015816;trans-synaptic signaling#GO:0099537;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;synaptic signaling#GO:0099536;nitrogen compound transport#GO:0071705;import into cell#GO:0098657;establishment of localization#GO:0051234;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;amino acid transport#GO:0006865;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000017470.3|UniProtKB=F6Z559 F6Z559 FAM167B PTHR32289:SF4 PROTEIN FAM167A PROTEIN FAM167B MONDO|Ensembl=ENSMODG00000004339.4|UniProtKB=F6W5E7 F6W5E7 ENPP6 PTHR10151:SF66 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE CHOLINEPHOSPHODIESTERASE ENPP6 hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000023448.3|UniProtKB=F6U555 F6U555 PTHR11559:SF179 CARBOXYLESTERASE LIVER CARBOXYLESTERASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;fatty acid catabolic process#GO:0009062;short-chain fatty acid catabolic process#GO:0019626;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lipid droplet#GO:0005811;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 esterase#PC00097 MONDO|Ensembl=ENSMODG00000003722.4|UniProtKB=F7EW99 F7EW99 STON2 PTHR10529:SF345 AP COMPLEX SUBUNIT MU STONIN-2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;regulation of localization#GO:0032879;receptor-mediated endocytosis#GO:0006898;regulation of transport#GO:0051049;intracellular transport#GO:0046907;regulation of endocytosis#GO:0030100;vacuolar transport#GO:0007034;synaptic vesicle cycle#GO:0099504;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;post-Golgi vesicle-mediated transport#GO:0006892;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;synaptic vesicle endocytosis#GO:0048488;regulation of biological process#GO:0050789;clathrin-dependent endocytosis#GO:0072583 plasma membrane#GO:0005886;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cell periphery#GO:0071944;cytosol#GO:0005829;vesicle membrane#GO:0012506;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;synaptic vesicle#GO:0008021;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane coat#GO:0030117;vesicle coat#GO:0030120;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;presynapse#GO:0098793;secretory vesicle#GO:0099503;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125;coated vesicle membrane#GO:0030662;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;synapse#GO:0045202;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;organelle subcompartment#GO:0031984;endocytic vesicle#GO:0030139;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000049205.1|UniProtKB=A0A5F8G377 A0A5F8G377 PTHR11927:SF9 GALACTOSIDE 2-L-FUCOSYLTRANSFERASE L-FUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000024412.2|UniProtKB=F7GG20 F7GG20 LOC100017748 PTHR48002:SF123 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4B1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009452.2|UniProtKB=A0A5F8H116 A0A5F8H116 PTHR12080:SF134 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE CD48 ANTIGEN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;immune system process#GO:0002376;cell activation#GO:0001775;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;leukocyte activation#GO:0045321;T cell activation#GO:0042110;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000017386.4|UniProtKB=A0A5F8G4T8 A0A5F8G4T8 CCDC28A PTHR13400:SF3 CHEMOKINE C-C MOTIF RECEPTOR 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 28A reproductive process#GO:0022414;male gamete generation#GO:0048232;gamete generation#GO:0007276;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000036406.1|UniProtKB=A0A5F8HHS2 A0A5F8HHS2 PTHR10206:SF2 CATHELICIDIN CATHELICIDIN ANTIMICROBIAL PEPTIDE lipopolysaccharide binding#GO:0001530;carbohydrate derivative binding#GO:0097367;binding#GO:0005488;lipid binding#GO:0008289 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to other organism#GO:0051707;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;response to external biotic stimulus#GO:0043207;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051 MONDO|Ensembl=ENSMODG00000019818.2|UniProtKB=F6STE0 F6STE0 LOC100021091 PTHR24103:SF676 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000021591.1|UniProtKB=Q65CI1 Q65CI1 MT-CYB PTHR19271:SF42 CYTOCHROME B CYTOCHROME B oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055 metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904 respiratory chain complex III#GO:0045275;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796 MONDO|Ensembl=ENSMODG00000027844.2|UniProtKB=F6U2N3 F6U2N3 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009646.4|UniProtKB=F6QTA6 F6QTA6 WT1 PTHR23235:SF49 KRUEPPEL-LIKE TRANSCRIPTION FACTOR WILMS TUMOR PROTEIN transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000048791.1|UniProtKB=A0A5F8GAM0 A0A5F8GAM0 PTHR21193:SF3 OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1 OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000007991.4|UniProtKB=F7D5D0 F7D5D0 SWAP70 PTHR14383:SF6 SWAP-70 RECOMBINASE SWITCH-ASSOCIATED PROTEIN 70 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;intracellular signal transduction#GO:0035556 intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;nucleus#GO:0005634;actin cytoskeleton#GO:0015629;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000028095.2|UniProtKB=K7E2B6 K7E2B6 PTHR10206:SF5 CATHELICIDIN CATHELICIDIN-RELATED PEPTIDE LUTZICIDIN-LIKE lipid binding#GO:0008289;lipopolysaccharide binding#GO:0001530;carbohydrate derivative binding#GO:0097367;binding#GO:0005488 antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to Gram-negative bacterium#GO:0050829;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to Gram-positive bacterium#GO:0050830;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051 MONDO|Ensembl=ENSMODG00000003695.3|UniProtKB=F7FAG1 F7FAG1 LOC100033297 PTHR24241:SF203 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PROKINETICIN RECEPTOR 1 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;circadian rhythm#GO:0007623;cell communication#GO:0007154;rhythmic process#GO:0048511;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004726.2|UniProtKB=F6Y299 F6Y299 USP10 PTHR24006:SF947 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 10 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;regulation of autophagy#GO:0010506;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;DNA damage response#GO:0006974;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;cellular process#GO:0009987;regulation of protein stability#GO:0031647;signal transduction#GO:0007165;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytosol#GO:0005829 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000025120.2|UniProtKB=F6R2H4 F6R2H4 MRPL36 PTHR46909:SF1 39S RIBOSOMAL PROTEIN L36, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL36M organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000046748.1|UniProtKB=A0A5F8GL49 A0A5F8GL49 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000025590.2|UniProtKB=F6U285 F6U285 PTHR48018:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8B8 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002472.4|UniProtKB=F7BW97 F7BW97 PTHR23030:SF39 PCD6 INTERACTING PROTEIN-RELATED PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN cell cycle process#GO:0022402;establishment of protein localization to vacuole#GO:0072666;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;cytokinesis#GO:0000910;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular localization#GO:0051641;cytoskeleton-dependent cytokinesis#GO:0061640;protein transport#GO:0015031;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;endosomal transport#GO:0016197;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cell division#GO:0051301;modification-dependent protein catabolic process#GO:0019941;mitotic cytokinesis#GO:0000281;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;protein localization to vacuole#GO:0072665;protein metabolic process#GO:0019538;localization#GO:0051179;macromolecule localization#GO:0033036;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;mitotic cell cycle process#GO:1903047 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000005227.5|UniProtKB=A0A5F8GK93 A0A5F8GK93 WDR26 PTHR22838:SF28 WD REPEAT PROTEIN 26-RELATED WD REPEAT-CONTAINING PROTEIN 26 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000010772.4|UniProtKB=F7CIV1 F7CIV1 CDK6 PTHR24056:SF130 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 6 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000004229.4|UniProtKB=F6UBM6 F6UBM6 MCM7 PTHR11630:SF26 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM7 binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000043037.1|UniProtKB=A0A5F8GLE5 A0A5F8GLE5 ZNF524 PTHR24390:SF109 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 524 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000014924.4|UniProtKB=F7FVR1 F7FVR1 NUFIP1 PTHR13309:SF0 NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 1 FMR1-INTERACTING PROTEIN NUFIP1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex assembly#GO:0022618;protein-RNA complex organization#GO:0071826;ribonucleoprotein complex biogenesis#GO:0022613;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000003615.4|UniProtKB=F7C6C4 F7C6C4 HTT PTHR10170:SF10 HUNTINGTON DISEASE PROTEIN HUNTINGTIN regulation of biological process#GO:0050789;central nervous system development#GO:0007417;cell differentiation#GO:0030154;establishment of organelle localization#GO:0051656;microtubule-based transport#GO:0099111;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic vesicle transport#GO:0048489;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;nervous system development#GO:0007399;synaptic vesicle localization#GO:0097479;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;organelle localization#GO:0051640;system development#GO:0048731;localization#GO:0051179;anatomical structure development#GO:0048856;vesicle localization#GO:0051648;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;transport#GO:0006810;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;vesicle cytoskeletal trafficking#GO:0099518;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;intracellular vesicle#GO:0097708;vesicle#GO:0031982;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;neuron projection#GO:0043005 Huntington disease#P00029>Htt#P00766;Huntington disease#P00029>PolyQ Htt#P00800;Huntington disease#P00029>PolyQ HTT#G01532;Huntington disease#P00029>Truncated Htt#P00761;Huntington disease#P00029>HTT#G01530 MONDO|Ensembl=ENSMODG00000015980.2|UniProtKB=F7EZN3 F7EZN3 LRRN3 PTHR24373:SF7 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT NEURONAL PROTEIN 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027559.2|UniProtKB=K7DYV7 K7DYV7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000038788.1|UniProtKB=A0A5F8GSL6 A0A5F8GSL6 SSBP1 PTHR10302:SF0 SINGLE-STRANDED DNA-BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN, MITOCHONDRIAL single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;molecular function activator activity#GO:0140677;DNA binding#GO:0003677;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of DNA replication#GO:0045740;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;regulation of DNA-templated DNA replication#GO:0090329;regulation of organelle organization#GO:0033043;regulation of DNA metabolic process#GO:0051052;DNA replication#GO:0006260;primary metabolic process#GO:0044238;positive regulation of DNA metabolic process#GO:0051054;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;positive regulation of cellular component organization#GO:0051130;regulation of DNA replication#GO:0006275;positive regulation of metabolic process#GO:0009893;positive regulation of organelle organization#GO:0010638 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;mitochondrion#GO:0005739;mitochondrial nucleoid#GO:0042645;nucleoid#GO:0009295;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000012076.4|UniProtKB=F7G4Z3 F7G4Z3 LRRC8C PTHR45752:SF24 LEUCINE-RICH REPEAT-CONTAINING VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8C channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 cell communication#GO:0007154;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;intracellular signal transduction#GO:0035556;monoatomic anion transport#GO:0006820;carbohydrate derivative transport#GO:1901264;cellular response to stimulus#GO:0051716;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;regulation of cellular process#GO:0050794;carboxylic acid transmembrane transport#GO:1905039;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810;establishment of localization#GO:0051234;aspartate transmembrane transport#GO:0015810;nitrogen compound transport#GO:0071705;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;dicarboxylic acid transport#GO:0006835;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;response to stimulus#GO:0050896;signaling#GO:0023052;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;organic acid transport#GO:0015849;acidic amino acid transport#GO:0015800;import into cell#GO:0098657;signal transduction#GO:0007165;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656 cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000023838.2|UniProtKB=F6U8J1 F6U8J1 LOC100023079 PTHR26453:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009357.4|UniProtKB=F7G0B1 F7G0B1 FSAF1 PTHR28366:SF1 CHROMOSOME 1 OPEN READING FRAME 131 40S SMALL SUBUNIT PROCESSOME ASSEMBLY FACTOR 1 MONDO|Ensembl=ENSMODG00000008330.5|UniProtKB=F7F302 F7F302 ABCD1 PTHR11384:SF21 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 1 nucleoside phosphate binding#GO:1901265;binding#GO:0005488;ATP binding#GO:0005524;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;carboxylic acid transmembrane transporter activity#GO:0046943;nucleotide binding#GO:0000166;monocarboxylic acid transmembrane transporter activity#GO:0008028;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857 organelle organization#GO:0006996;cellular process#GO:0009987;lipid catabolic process#GO:0016042;establishment of localization in cell#GO:0051649;metabolic process#GO:0008152;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;fatty acid oxidation#GO:0019395;cellular component organization or biogenesis#GO:0071840;carboxylic acid metabolic process#GO:0019752;cellular component organization#GO:0016043;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;very long-chain fatty acid metabolic process#GO:0000038;lipid localization#GO:0010876;oxoacid metabolic process#GO:0043436;peroxisome organization#GO:0007031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;fatty acid catabolic process#GO:0009062;macromolecule localization#GO:0033036;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;lipid transport#GO:0006869;intracellular transport#GO:0046907;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;transport#GO:0006810;fatty acid beta-oxidation#GO:0006635;establishment of localization#GO:0051234;lipid modification#GO:0030258;primary metabolic process#GO:0044238;catabolic process#GO:0009056;carboxylic acid transmembrane transport#GO:1905039;lipid oxidation#GO:0034440;localization#GO:0051179;fatty acid transport#GO:0015908;peroxisomal transport#GO:0043574;monocarboxylic acid transport#GO:0015718 peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000020494.4|UniProtKB=F7F534 F7F534 ALX1 PTHR24329:SF359 HOMEOBOX PROTEIN ARISTALESS ALX HOMEOBOX PROTEIN 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;skeletal system morphogenesis#GO:0048705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;positive regulation of RNA metabolic process#GO:0051254;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;embryo development#GO:0009790;nervous system development#GO:0007399;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;cell development#GO:0048468;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;skeletal system development#GO:0001501;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;neuron development#GO:0048666;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000044025.1|UniProtKB=A0A5F8G822 A0A5F8G822 PTHR48015:SF22 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE PAK 2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell migration#GO:0016477;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to nutrient levels#GO:0031667;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to starvation#GO:0009267;regulation of MAPK cascade#GO:0043408;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to starvation#GO:0042594;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Ras Pathway#P04393>PAK#P04553;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;T cell activation#P00053>PAK#P01319;Angiogenesis#P00005>PAK#P00249 MONDO|Ensembl=ENSMODG00000005588.4|UniProtKB=F7DK16 F7DK16 FAP PTHR11731:SF136 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED PROLYL ENDOPEPTIDASE FAP catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000005536.4|UniProtKB=F7DNH8 F7DNH8 LRRC74A PTHR24114:SF50 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 74A MONDO|Ensembl=ENSMODG00000006058.4|UniProtKB=A0A5F8HBA6 A0A5F8HBA6 TMEM208 PTHR13505:SF7 TRANSMEMBRANE PROTEIN 208 TRANSMEMBRANE PROTEIN 208 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000001804.4|UniProtKB=F6T5Y2 F6T5Y2 MFSD4A PTHR23121:SF10 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SOLUTE CARRIER FAMILY 60 MEMBER 1 transporter#PC00227 MONDO|Ensembl=ENSMODG00000018967.2|UniProtKB=F7G044 F7G044 YIPF3 PTHR15627:SF14 NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1 PROTEIN YIPF3 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000000564.4|UniProtKB=F6X4X5 F6X4X5 PLAU PTHR24264:SF38 TRYPSIN-RELATED UROKINASE-TYPE PLASMINOGEN ACTIVATOR catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;negative regulation of response to stimulus#GO:0048585;regulation of coagulation#GO:0050818;regulation of hemostasis#GO:1900046;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;negative regulation of wound healing#GO:0061045;plasminogen activation#GO:0031639;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of blood coagulation#GO:0030195;regulation of cellular process#GO:0050794;regulation of cell adhesion mediated by integrin#GO:0033628;primary metabolic process#GO:0044238;negative regulation of multicellular organismal process#GO:0051241;protein metabolic process#GO:0019538;regulation of multicellular organismal process#GO:0051239;negative regulation of response to external stimulus#GO:0032102;protein maturation#GO:0051604;regulation of response to external stimulus#GO:0032101;gene expression#GO:0010467;fibrinolysis#GO:0042730;cellular process#GO:0009987;regulation of response to wounding#GO:1903034;negative regulation of response to wounding#GO:1903035;metabolic process#GO:0008152;regulation of wound healing#GO:0061041;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;regulation of biological process#GO:0050789;zymogen activation#GO:0031638;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;negative regulation of coagulation#GO:0050819;negative regulation of hemostasis#GO:1900047;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 Plasminogen activating cascade#P00050>uPA#P01243;CCKR signaling map#P06959>uPA#P07039;CCKR signaling map#P06959>uPA#G06974;CCKR signaling map#P06959>uPA#G07267;Plasminogen activating cascade#P00050>pro-uPA#P01262;Blood coagulation#P00011>uPA#P00424;Blood coagulation#P00011>uPAR#P00433 MONDO|Ensembl=ENSMODG00000013618.4|UniProtKB=A0A5F8HC97 A0A5F8HC97 COMMD10 PTHR12333:SF0 COMM DOMAIN CONTAINING PROTEIN 10 COMM DOMAIN-CONTAINING PROTEIN 10 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000025555.3|UniProtKB=F6UIJ7 F6UIJ7 TMEM45A PTHR16007:SF21 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45A MONDO|Ensembl=ENSMODG00000000456.3|UniProtKB=F6US57 F6US57 FAM83D PTHR16181:SF30 PROTEIN FAM83A-RELATED PROTEIN FAM83D protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;positive regulation of cell cycle G1/S phase transition#GO:1902808;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;protein localization to cytoskeleton#GO:0044380;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;intracellular protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;macromolecule localization#GO:0033036;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;protein localization to microtubule cytoskeleton#GO:0072698;localization#GO:0051179;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;regulation of cell communication#GO:0010646;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365 organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;mitotic spindle pole#GO:0097431;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000009081.4|UniProtKB=F7FQV1 F7FQV1 DBX1 PTHR24331:SF6 DBX HOMEOBOX PROTEIN DBX1 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252 MONDO|Ensembl=ENSMODG00000004581.4|UniProtKB=F6R440 F6R440 TFR2 PTHR10404:SF33 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE TRANSFERRIN RECEPTOR PROTEIN 2 carboxypeptidase activity#GO:0004180;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;catalytic activity#GO:0003824 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000011991.4|UniProtKB=F7B938 F7B938 ATP2C1 PTHR42861:SF2 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE TYPE 2C MEMBER 1 ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;calcium ion homeostasis#GO:0055074;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000007241.4|UniProtKB=F7CRU2 F7CRU2 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000011757.4|UniProtKB=A0A5F8H1U4 A0A5F8H1U4 POLL PTHR11276:SF28 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA POLYMERASE LAMBDA DNA-directed DNA polymerase activity#GO:0003887;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097 double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000046234.1|UniProtKB=A0A5F8G5N8 A0A5F8G5N8 PDE6D PTHR12976:SF0 RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE DELTA-SUBUNIT RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT DELTA cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000019180.4|UniProtKB=F7AX77 F7AX77 RHBDL3 PTHR45840:SF5 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 3 catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 MONDO|Ensembl=ENSMODG00000009526.3|UniProtKB=Q95J82 Q95J82 FSHB PTHR11515:SF17 GLYCOPROTEIN HORMONE BETA CHAIN FOLLITROPIN SUBUNIT BETA hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 animal organ development#GO:0048513;multicellular organism development#GO:0007275;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;multicellular organismal process#GO:0032501;gonad development#GO:0008406;biological regulation#GO:0065007;sex differentiation#GO:0007548;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure development#GO:0048856;cell communication#GO:0007154;reproductive system development#GO:0061458;multicellular organismal reproductive process#GO:0048609;female gonad development#GO:0008585;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;rhythmic process#GO:0048511;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;reproductive process#GO:0022414;reproductive structure development#GO:0048608;signaling#GO:0023052;developmental process involved in reproduction#GO:0003006;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>3' FSHbeta#G06900;Gonadotropin-releasing hormone receptor pathway#P06664>5' FSHbeta#G06904;Gonadotropin-releasing hormone receptor pathway#P06664>FSHbeta#P06809;Gonadotropin-releasing hormone receptor pathway#P06664>FSHbeta#G06678 MONDO|Ensembl=ENSMODG00000051494.1|UniProtKB=A0A5F8H3P8 A0A5F8H3P8 PTHR16675:SF289 MHC CLASS I-RELATED ZINC-ALPHA-2-GLYCOPROTEIN biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of immune system process#GO:0002684;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706 side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000009203.3|UniProtKB=F6YZZ1 F6YZZ1 PTHR23419:SF1 DIVALENT CATION TOLERANCE CUTA-RELATED PROTEIN CUTA metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;copper ion binding#GO:0005507;ion binding#GO:0043167;transition metal ion binding#GO:0046914 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000001697.4|UniProtKB=A0A5F8GGP3 A0A5F8GGP3 STK32B PTHR24356:SF157 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 32B catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000023284.2|UniProtKB=F6SDC7 F6SDC7 NRARP PTHR24203:SF75 ANKYRIN REPEAT FAMILY PROTEIN NOTCH-REGULATED ANKYRIN REPEAT-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000037364.1|UniProtKB=A0A5F8HH37 A0A5F8HH37 LOC100012910 PTHR13042:SF0 UBIQUITIN-LIKE PROTEIN 5 UBIQUITIN-LIKE PROTEIN 5 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000029636.2|UniProtKB=A0A5F8GU60 A0A5F8GU60 PTHR24089:SF262 SOLUTE CARRIER FAMILY 25 SOLUTE CARRIER FAMILY 25 MEMBER 24 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;localization#GO:0051179;organophosphate ester transport#GO:0015748;nitrogen compound transport#GO:0071705;transport#GO:0006810;carbohydrate derivative transport#GO:1901264 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 MONDO|Ensembl=ENSMODG00000042139.1|UniProtKB=A0A5F8GFZ5 A0A5F8GFZ5 LOC100026503 PTHR20978:SF0 SPLICING FACTOR 3B SUBUNIT 5 SPLICING FACTOR 3B SUBUNIT 5 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000003307.3|UniProtKB=F7DZ27 F7DZ27 MRM1 PTHR46103:SF3 RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;rRNA (guanine) methyltransferase activity#GO:0016435;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a rRNA#GO:0140102 nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000021422.4|UniProtKB=A0A5F8H0Y7 A0A5F8H0Y7 PTPN2 PTHR46047:SF1 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 2 phosphoprotein phosphatase activity#GO:0004721;protein binding#GO:0005515;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000049395.1|UniProtKB=A0A5F8HJ10 A0A5F8HJ10 PTHR11528:SF87 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-ALPHA hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ATP-dependent activity#GO:0140657;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817 protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;protein folding#GO:0006457;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;protein stabilization#GO:0050821;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;biological regulation#GO:0065007;response to heat#GO:0009408;cellular response to heat#GO:0034605;response to stress#GO:0006950;regulation of protein stability#GO:0031647;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cell periphery#GO:0071944;nucleus#GO:0005634;cytosol#GO:0005829;membrane#GO:0016020;perinuclear region of cytoplasm#GO:0048471;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;myelin sheath#GO:0043209;cytoplasm#GO:0005737;cell body#GO:0044297;neuronal cell body#GO:0043025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Hsp90 family chaperone#PC00028;chaperone#PC00072 MONDO|Ensembl=ENSMODG00000008381.3|UniProtKB=F6SJS4 F6SJS4 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000001464.4|UniProtKB=F7APQ1 F7APQ1 SNX13 PTHR22775:SF51 SORTING NEXIN SORTING NEXIN-13 ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS-PX1#P00706 MONDO|Ensembl=ENSMODG00000019691.5|UniProtKB=H9H7E8 H9H7E8 FAM83C PTHR16181:SF29 PROTEIN FAM83A-RELATED PROTEIN FAM83C kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 MONDO|Ensembl=ENSMODG00000025355.2|UniProtKB=A0A5F8G482 A0A5F8G482 OPN1LW PTHR24240:SF17 OPSIN MEDIUM-WAVE-SENSITIVE OPSIN 1-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;biological regulation#GO:0065007;detection of stimulus#GO:0051606;response to radiation#GO:0009314;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to radiation#GO:0071478;signaling#GO:0023052;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cilium#GO:0005929;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000028455.2|UniProtKB=K7E326 K7E326 CFAP77 PTHR28617:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 77 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 77 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000016805.4|UniProtKB=F7FVH9 F7FVH9 CIAO3 PTHR11615:SF322 NITRATE, FORMATE, IRON DEHYDROGENASE CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 3 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000024556.2|UniProtKB=F7F1Q2 F7F1Q2 PTHR12002:SF41 CLAUDIN CLAUDIN-6 virus receptor activity#GO:0001618;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329 apical junction complex#GO:0043296;anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165 cell junction protein#PC00070;tight junction#PC00214 MONDO|Ensembl=ENSMODG00000014308.4|UniProtKB=F7GCG4 F7GCG4 VAC14 PTHR16023:SF0 TAX1 BINDING PROTEIN-RELATED PROTEIN VAC14 HOMOLOG phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;metabolic process#GO:0008152 cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;vesicle membrane#GO:0012506;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017609.3|UniProtKB=F7AH78 F7AH78 PTHR16019:SF6 SYNAPSE-ASSOCIATED PROTEIN SYNAPSE-ASSOCIATED PROTEIN 1 cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;TOR signaling#GO:0031929;biological regulation#GO:0065007;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;TORC2 signaling#GO:0038203;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;positive regulation of fat cell differentiation#GO:0045600;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;synapse#GO:0045202;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000003199.4|UniProtKB=F6VFY1 F6VFY1 MPV17L2 PTHR11266:SF8 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MPV17-LIKE PROTEIN 2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000007678.4|UniProtKB=F7FNF8 F7FNF8 HIPK4 PTHR24058:SF46 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 4 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000007794.4|UniProtKB=F7A8H9 F7A8H9 NEDD1 PTHR44414:SF1 PROTEIN NEDD1 PROTEIN NEDD1 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;mitotic cell cycle#GO:0000278 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spindle pole#GO:0000922;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoplasm#GO:0005737;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000037772.1|UniProtKB=A0A5F8HG76 A0A5F8HG76 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012039.4|UniProtKB=F7EGC5 F7EGC5 RNF34 PTHR14879:SF3 CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF34 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;protein metabolic process#GO:0019538;regulation of extrinsic apoptotic signaling pathway#GO:2001236;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of apoptotic process#GO:0042981;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000017073.4|UniProtKB=A0A5F8H1T1 A0A5F8H1T1 SCAMP3 PTHR10687:SF6 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 3 export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;secretion by cell#GO:0032940;exocytosis#GO:0006887;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810 recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;trans-Golgi network membrane#GO:0032588;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000005424.4|UniProtKB=F7D0S8 F7D0S8 THYN1 PTHR14087:SF7 THYMOCYTE NUCLEAR PROTEIN 1 THYMOCYTE NUCLEAR PROTEIN 1 MONDO|Ensembl=ENSMODG00000020132.4|UniProtKB=A0A5F8HHW8 A0A5F8HHW8 NR2F1 PTHR24083:SF168 NUCLEAR HORMONE RECEPTOR COUP TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;nervous system development#GO:0007399;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000003202.4|UniProtKB=A0A5F8GTQ6 A0A5F8GTQ6 NCBP1 PTHR12412:SF3 CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nuclear-transcribed mRNA catabolic process#GO:0000956;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;transport#GO:0006810;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nitrogen compound transport#GO:0071705;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid transport#GO:0050657;localization#GO:0051179;regulation of RNA metabolic process#GO:0051252;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;RNA localization#GO:0006403;regulation of cellular process#GO:0050794;RNA transport#GO:0050658;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;gene expression#GO:0010467;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000008580.5|UniProtKB=A0A5F8H028 A0A5F8H028 ZNRF3 PTHR16200:SF3 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE ZNRF3 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;signaling receptor binding#GO:0005102;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of cell communication#GO:0010648;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000040191.1|UniProtKB=A0A5F8HAS2 A0A5F8HAS2 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000045888.1|UniProtKB=A0A5F8GZM4 A0A5F8GZM4 PTHR13390:SF4 LIPASE LIPID DROPLET-ASSOCIATED HYDROLASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular component organization or biogenesis#GO:0071840;cholesterol homeostasis#GO:0042632;lipid droplet organization#GO:0034389;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592;organelle organization#GO:0006996;lipid homeostasis#GO:0055088;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;lipase#PC00143 MONDO|Ensembl=ENSMODG00000038417.1|UniProtKB=A0A5F8H5T5 A0A5F8H5T5 MED10 PTHR13345:SF13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 general transcription factor#PC00259;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000010766.4|UniProtKB=H9H6F2 H9H6F2 PHF21B PTHR24102:SF18 PHD FINGER PROTEIN PHD FINGER PROTEIN 21B MONDO|Ensembl=ENSMODG00000048262.1|UniProtKB=A0A5F8G5V2 A0A5F8G5V2 LOC100617041 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005247.3|UniProtKB=F6YMT5 F6YMT5 PPOX PTHR42923:SF3 PROTOPORPHYRINOGEN OXIDASE PROTOPORPHYRINOGEN OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 Heme biosynthesis#P02746>Protoporphyrinogen oxidase#P02976 MONDO|Ensembl=ENSMODG00000018495.4|UniProtKB=F7BRK1 F7BRK1 SENP6 PTHR46896:SF1 SENTRIN-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 6 hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;ubiquitin-like protein peptidase activity#GO:0019783 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;post-translational protein modification#GO:0043687;regulation of organelle assembly#GO:1902115;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of spindle assembly#GO:0090169;protein modification by small protein conjugation or removal#GO:0070647;regulation of microtubule-based process#GO:0032886;regulation of cytoskeleton organization#GO:0051493;regulation of spindle organization#GO:0090224;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000000020.5|UniProtKB=A0A5F8GC10 A0A5F8GC10 MXRA5 PTHR24369:SF163 ANTIGEN BSP, PUTATIVE-RELATED MATRIX-REMODELING-ASSOCIATED PROTEIN 5 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000029213.2|UniProtKB=K7E3F3 K7E3F3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000013682.3|UniProtKB=A0A5F8HF15 A0A5F8HF15 SHMT1 PTHR11680:SF59 SERINE HYDROXYMETHYLTRANSFERASE SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;tetrahydrofolate metabolic process#GO:0046653;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 mitochondrion#GO:0005739;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 Serine glycine biosynthesis#P02776>Glycine hydroxymethyltransferase#P03158 MONDO|Ensembl=ENSMODG00000037967.1|UniProtKB=A0A5F8GJY1 A0A5F8GJY1 PTHR15901:SF15 TESTICULAR HAPLOID EXPRESSED GENE PROTEIN SPERM MICROTUBULE ASSOCIATED PROTEIN 2-LIKE MONDO|Ensembl=ENSMODG00000011371.4|UniProtKB=A0A5F8GVT7 A0A5F8GVT7 PFKFB1 PTHR10606:SF15 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE 1 phosphoric ester hydrolase activity#GO:0042578;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphatase activity#GO:0016791;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphotransferase activity, alcohol group as acceptor#GO:0016773;sugar-phosphatase activity#GO:0050308 organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 carbohydrate phosphatase#PC00066;hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000017869.4|UniProtKB=F6YI65 F6YI65 AGO3 PTHR22891:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-3 RNA binding#GO:0003723;nuclease activity#GO:0004518;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA nuclease activity#GO:0004540;single-stranded RNA binding#GO:0003727;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulatory ncRNA-mediated gene silencing#GO:0031047;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;RNA metabolic process#GO:0016070;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000023822.2|UniProtKB=F6Y6I2 F6Y6I2 PTHR11482:SF42 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;ornithine decarboxylase activity#GO:0004586;lyase activity#GO:0016829 polyamine biosynthetic process#GO:0006596;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;metabolic process#GO:0008152;amine metabolic process#GO:0009308;polyamine metabolic process#GO:0006595;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 CCKR signaling map#P06959>ODC1#G06989;CCKR signaling map#P06959>ODC1#P07221;Ornithine degradation#P02758>Ornithine decarboxylase#P03053 MONDO|Ensembl=ENSMODG00000044468.1|UniProtKB=A0A5F8HBA9 A0A5F8HBA9 FOXD4 PTHR11829:SF420 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D4-LIKE 3-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000012377.4|UniProtKB=F6QHB6 F6QHB6 PTHR22736:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 66 COILED-COIL DOMAIN CONTAINING 66 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 MONDO|Ensembl=ENSMODG00000010664.4|UniProtKB=F7CKG2 F7CKG2 PTHR11269:SF9 PERIOD CIRCADIAN PROTEIN PERIOD CIRCADIAN PROTEIN HOMOLOG 2 transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of macromolecule biosynthetic process#GO:0010558;rhythmic process#GO:0048511;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;negative regulation of biological process#GO:0048519;circadian regulation of gene expression#GO:0032922;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;photoperiodism#GO:0009648;regulation of biosynthetic process#GO:0009889;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of circadian rhythm#GO:0042752;response to radiation#GO:0009314;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;response to light stimulus#GO:0009416;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 transcription cofactor#PC00217 Circadian clock system#P00015>per#G01503;Circadian clock system#P00015>per#G01499;Circadian clock system#P00015>Per#P00504 MONDO|Ensembl=ENSMODG00000018497.4|UniProtKB=A0A5F8GJD0 A0A5F8GJD0 FILIP1 PTHR23166:SF3 FILAMIN/GPBP-INTERACTING PROTEIN FILAMIN-A-INTERACTING PROTEIN 1 macromolecule localization#GO:0033036;protein localization to cytoskeleton#GO:0044380;localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000016590.4|UniProtKB=F7A1W6 F7A1W6 PRSS22 PTHR24253:SF6 TRANSMEMBRANE PROTEASE SERINE BRAIN-SPECIFIC SERINE PROTEASE 4 serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000023032.3|UniProtKB=F6XG21 F6XG21 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000018361.5|UniProtKB=F6PPW8 F6PPW8 TBX18 PTHR11267:SF20 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX18 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;regionalization#GO:0003002;tissue development#GO:0009888;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;cell fate commitment#GO:0045165;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;anterior/posterior pattern specification#GO:0009952;cell fate specification#GO:0001708;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;anatomical structure formation involved in morphogenesis#GO:0048646;morphogenesis of an epithelium#GO:0002009;cellular process#GO:0009987;embryo development#GO:0009790 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 MONDO|Ensembl=ENSMODG00000044063.1|UniProtKB=A0A5F8HGR1 A0A5F8HGR1 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000023030.3|UniProtKB=F6T0S6 F6T0S6 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000018112.4|UniProtKB=K7DZC8 K7DZC8 ATG3 PTHR12866:SF2 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein conjugating enzyme activity#GO:0061650;aminoacyltransferase activity#GO:0016755 autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;glycogen catabolic process#GO:0005980;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;autophagy of mitochondrion#GO:0000422;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;polysaccharide catabolic process#GO:0000272;glycogen metabolic process#GO:0005977;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;glucan catabolic process#GO:0009251;catabolic process#GO:0009056;polysaccharide metabolic process#GO:0005976;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052 phagophore assembly site#GO:0000407;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000025552.3|UniProtKB=F6UIM3 F6UIM3 SPINDOC PTHR34589:SF1 SIMILAR TO RIKEN CDNA 2700081O15 SPINDLIN INTERACTOR AND REPRESSOR OF CHROMATIN-BINDING PROTEIN negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 MONDO|Ensembl=ENSMODG00000019385.4|UniProtKB=F6WCT9 F6WCT9 SAXO2 PTHR31516:SF6 STABILIZER OF AXONEMAL MICROTUBULES 2 STABILIZER OF AXONEMAL MICROTUBULES 2 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729;microtubule#GO:0005874;axoneme#GO:0005930;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic microtubule#GO:0005881;organelle#GO:0043226;motile cilium#GO:0031514;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;ciliary plasm#GO:0097014;sperm flagellum#GO:0036126;supramolecular polymer#GO:0099081;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000010598.3|UniProtKB=F7G8G3 F7G8G3 GPR55 PTHR24232:SF56 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 55 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000007359.3|UniProtKB=F6TNL8 F6TNL8 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002999.4|UniProtKB=F6Q3V3 F6Q3V3 DCAF10 PTHR14588:SF2 DDB1- AND CUL4-ASSOCIATED FACTOR 10 DDB1- AND CUL4-ASSOCIATED FACTOR 10 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 MONDO|Ensembl=ENSMODG00000013814.4|UniProtKB=F6SXC8 F6SXC8 SVOPL PTHR24064:SF457 SOLUTE CARRIER FAMILY 22 MEMBER TRANSPORTER SVOPL-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000017148.4|UniProtKB=F6TLZ1 F6TLZ1 SLC2A1 PTHR23503:SF51 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 1 carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739;transport#GO:0006810;carbohydrate transport#GO:0008643;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 Gonadotropin-releasing hormone receptor pathway#P06664>Glut1#G06890;Gonadotropin-releasing hormone receptor pathway#P06664>Glut1#P06724;Gonadotropin-releasing hormone receptor pathway#P06664>Glut1#G06675 MONDO|Ensembl=ENSMODG00000011228.4|UniProtKB=F6S782 F6S782 KIF15 PTHR24115:SF1004 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF15 isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000008274.2|UniProtKB=A0A5F8GXV0 A0A5F8GXV0 PTHR10343:SF96 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1 protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 MONDO|Ensembl=ENSMODG00000010054.4|UniProtKB=F6TCV7 F6TCV7 ITGA8 PTHR23220:SF5 INTEGRIN ALPHA INTEGRIN ALPHA-8 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;membrane#GO:0016020;membrane protein complex#GO:0098796;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 integrin#PC00126;cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Collagen#P00922;Integrin signalling pathway#P00034>Integrin alpha#P00941 MONDO|Ensembl=ENSMODG00000047193.1|UniProtKB=F7FQ46 F7FQ46 PTHR24381:SF479 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 432 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025244.2|UniProtKB=F7F5Y4 F7F5Y4 ENC1 PTHR24410:SF5 HL07962P-RELATED ECTODERM-NEURAL CORTEX PROTEIN 1 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000007277.4|UniProtKB=F7FQL0 F7FQL0 CREB3 PTHR45996:SF4 AGAP001464-PB CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Transcription regulation by bZIP transcription factor#P00055>CREB#P01383 MONDO|Ensembl=ENSMODG00000008149.4|UniProtKB=A0A5F8GLZ6 A0A5F8GLZ6 MTFR1 PTHR14215:SF1 PROTEIN OF UNKNOWN FUNCTION DUF729 MITOCHONDRIAL FISSION REGULATOR 1 aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;organelle fission#GO:0048285;cellular respiration#GO:0045333;cellular component organization or biogenesis#GO:0071840;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;mitochondrion organization#GO:0007005;mitochondrial fission#GO:0000266;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000012274.4|UniProtKB=F6YG68 F6YG68 ABHD18 PTHR13617:SF14 PROTEIN ABHD18 CARDIOLIPIN-SPECIFIC DEACYLASE, MITOCHONDRIAL phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 MONDO|Ensembl=ENSMODG00000008601.4|UniProtKB=F7BTY0 F7BTY0 DNAAF5 PTHR16216:SF11 DYNEIN ASSEMBLY FACTOR 5, AXONEMAL DYNEIN AXONEMAL ASSEMBLY FACTOR 5 binding#GO:0005488;protein binding#GO:0005515 plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;inner dynein arm assembly#GO:0036159;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000003487.4|UniProtKB=F7CSQ7 F7CSQ7 COX15 PTHR23289:SF2 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 HEME A SYNTHASE COX15 chaperone#PC00072 Vitamin D metabolism and pathway#P04396>FDX#P04607 MONDO|Ensembl=ENSMODG00000008186.4|UniProtKB=F7E4F6 F7E4F6 BBS1 PTHR20870:SF0 BARDET-BIEDL SYNDROME 1 PROTEIN BBSOME COMPLEX MEMBER BBS1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cilium organization#GO:0044782;localization#GO:0051179;non-motile cilium assembly#GO:1905515;organelle assembly#GO:0070925;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;cilium assembly#GO:0060271;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;BBSome#GO:0034464;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;membraneless organelle#GO:0043228;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930 MONDO|Ensembl=ENSMODG00000019080.3|UniProtKB=F7FNM5 F7FNM5 PTHR16784:SF2 ENAMELIN ENAMELIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;odontogenesis#GO:0042476;regulation of developmental process#GO:0050793;animal organ morphogenesis#GO:0009887;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;cellular process#GO:0009987;amelogenesis#GO:0097186;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;odontogenesis of dentin-containing tooth#GO:0042475;epithelium development#GO:0060429;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;anatomical structure formation involved in morphogenesis#GO:0048646;cellular developmental process#GO:0048869;animal organ development#GO:0048513 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000003513.3|UniProtKB=F7D2R9 F7D2R9 FLRT2 PTHR45712:SF16 AGAP008170-PA LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000004534.4|UniProtKB=F6QHC1 F6QHC1 CARS2 PTHR10890:SF27 CYSTEINYL-TRNA SYNTHETASE CYSTEINE--TRNA LIGASE, MITOCHONDRIAL-RELATED ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000005775.3|UniProtKB=F6XY80 F6XY80 GRPEL2 PTHR21237:SF10 GRPE PROTEIN GRPE PROTEIN HOMOLOG 2, MITOCHONDRIAL molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036 mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000019885.5|UniProtKB=A0A5F8HDB1 A0A5F8HDB1 LARGE2 PTHR12270:SF23 GLYCOSYLTRANSFERASE-RELATED XYLOSYL- AND GLUCURONYLTRANSFERASE LARGE2 glucuronosyltransferase activity#GO:0015020;pentosyltransferase activity#GO:0016763;xylosyltransferase activity#GO:0042285;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000002495.4|UniProtKB=F7BVM2 F7BVM2 C2H1orf87 PTHR34830:SF1 SIMILAR TO HYPOTHETICAL PROTEIN MGC34837 SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 87 MONDO|Ensembl=ENSMODG00000025012.2|UniProtKB=F6SWM3 F6SWM3 PTHR13229:SF2 PROTEIN KISH-A PROTEIN KISH-A transport#GO:0006810;establishment of protein localization to extracellular region#GO:0035592;protein transport#GO:0015031;secretion by cell#GO:0032940;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;secretion#GO:0046903;protein secretion#GO:0009306;localization#GO:0051179;protein localization to extracellular region#GO:0071692;cellular process#GO:0009987;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;export from cell#GO:0140352 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000023502.3|UniProtKB=F7EGL5 F7EGL5 PTHR26453:SF156 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004428.4|UniProtKB=F7CZQ0 F7CZQ0 PTHR22776:SF26 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 5 regulation of biological process#GO:0050789;immune response#GO:0006955;immune system process#GO:0002376;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000012634.4|UniProtKB=F6WU43 F6WU43 RPL23 PTHR11761:SF8 50S/60S RIBOSOMAL PROTEIN L14/L23 LARGE RIBOSOMAL SUBUNIT PROTEIN UL14 structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676 ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000021095.4|UniProtKB=A0A5F8GLR6 A0A5F8GLR6 CASK PTHR23122:SF40 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PERIPHERAL PLASMA MEMBRANE PROTEIN CASK protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of neurotransmitter secretion#GO:0046928;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of biological process#GO:0050789;localization#GO:0051179;regulation of secretion#GO:0051046;regulation of secretion by cell#GO:1903530;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;regulation of localization#GO:0032879;regulation of transport#GO:0051049 anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;cell-cell junction#GO:0005911;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 scaffold/adaptor protein#PC00226 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Parkinson disease#P00049>CASK#P01232 MONDO|Ensembl=ENSMODG00000040722.1|UniProtKB=A0A5F8G4N9 A0A5F8G4N9 LOC100028602 PTHR13255:SF1 ATAXIN-10 ATAXIN-10 neuron development#GO:0048666;cilium organization#GO:0044782;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular component organization#GO:0016043;cilium assembly#GO:0060271;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;organelle organization#GO:0006996 neuron projection#GO:0043005;cytosol#GO:0005829;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000051374.1|UniProtKB=A0A5F8GQK2 A0A5F8GQK2 FEM1C PTHR24173:SF14 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG C ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018085.3|UniProtKB=A0A5F8GBF5 A0A5F8GBF5 PTHR15317:SF1 T-CELL SURFACE PROTEIN TACTILE T-CELL SURFACE PROTEIN TACTILE cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000012074.3|UniProtKB=F7G4Z7 F7G4Z7 AGPAT5 PTHR10983:SF73 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE EPSILON acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;metabolic process#GO:0008152;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042;transferase#PC00220 MONDO|Ensembl=ENSMODG00000006280.4|UniProtKB=A0A5F8GSH8 A0A5F8GSH8 MKRN2 PTHR11224:SF17 MAKORIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE MAKORIN-2 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000036977.1|UniProtKB=A0A5F8GP26 A0A5F8GP26 PTHR24390:SF290 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 184 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000002731.3|UniProtKB=F6Z7A6 F6Z7A6 PADI3 PTHR10837:SF21 PEPTIDYLARGININE DEIMINASE PROTEIN-ARGININE DEIMINASE TYPE-3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000005606.4|UniProtKB=A0A5F8GSA7 A0A5F8GSA7 DZANK1 PTHR16058:SF4 DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;sensory system development#GO:0048880;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;animal organ development#GO:0048513;neuron differentiation#GO:0030182;developmental process#GO:0032502;sensory organ development#GO:0007423;visual system development#GO:0150063;cell development#GO:0048468;cell differentiation#GO:0030154;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887;anatomical structure morphogenesis#GO:0009653;system development#GO:0048731;neuron development#GO:0048666;eye development#GO:0001654;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 MONDO|Ensembl=ENSMODG00000019373.4|UniProtKB=F6WSP2 F6WSP2 RAMAC PTHR48168:SF1 RNA GUANINE-7 METHYLTRANSFERASE-ACTIVATING SUBUNIT-LIKE (PSEUDOGENE)-RELATED RNA GUANINE-N7 METHYLTRANSFERASE ACTIVATING SUBUNIT-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;RNA binding#GO:0003723;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000021233.3|UniProtKB=F6U0J1 F6U0J1 GRK7 PTHR24355:SF12 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE RHODOPSIN KINASE GRK7 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701 MONDO|Ensembl=ENSMODG00000007415.4|UniProtKB=F7GKH7 F7GKH7 SLCO5A1 PTHR11388:SF142 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 5A1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000000214.4|UniProtKB=A0A5F8GS49 A0A5F8GS49 TTI1 PTHR18460:SF3 TEL2 INTERACTING PROTEIN 1 TTI1 FAMILY MEMBER TELO2-INTERACTING PROTEIN 1 HOMOLOG cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000016930.4|UniProtKB=A0A5F8G1N6 A0A5F8G1N6 SUV39H2 PTHR46223:SF2 HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H2 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000003773.4|UniProtKB=F7AAE6 F7AAE6 CFAP53 PTHR31183:SF1 TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN FAMILY MEMBER CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 53 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000015295.4|UniProtKB=A0A5F8GD71 A0A5F8GD71 GPC4 PTHR10822:SF25 GLYPICAN GLYPICAN-4 biological regulation#GO:0065007;cell migration#GO:0016477;regulation of synapse assembly#GO:0051963;cellular process#GO:0009987;regulation of protein localization to membrane#GO:1905475;cell-cell adhesion#GO:0098609;regulation of localization#GO:0032879;cellular component organization or biogenesis#GO:0071840;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;cell motility#GO:0048870;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;synaptic membrane adhesion#GO:0099560;regulation of protein localization#GO:0032880;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;cell adhesion#GO:0007155;synapse organization#GO:0050808 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell surface#GO:0009986;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020200.4|UniProtKB=F7G832 F7G832 OSBP PTHR10972:SF205 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN 1 sterol binding#GO:0032934;binding#GO:0005488;lipid binding#GO:0008289;steroid binding#GO:0005496 cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000027707.2|UniProtKB=K7E0W0 K7E0W0 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000008885.4|UniProtKB=A0A5F8HA73 A0A5F8HA73 PPHLN1 PTHR15836:SF4 PERIPHILIN 1 PERIPHILIN-1 localization#GO:0051179;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;intracellular protein localization#GO:0008104;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;macromolecule localization#GO:0033036;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000006275.4|UniProtKB=F7FDN8 F7FDN8 ANKRD46 PTHR24166:SF28 ROLLING PEBBLES, ISOFORM B ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 46 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000016154.4|UniProtKB=F7D6I3 F7D6I3 CRAMP1 PTHR21677:SF1 CRAMPED PROTEIN PROTEIN CRAMPED-LIKE chromatin binding#GO:0003682;binding#GO:0005488 developmental process#GO:0032502;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000005959.3|UniProtKB=A0A5F8G4G9 A0A5F8G4G9 MCUB PTHR13462:SF6 CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL CALCIUM UNIPORTER REGULATORY SUBUNIT MCUB, MITOCHONDRIAL transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;ion channel inhibitor activity#GO:0008200;calcium channel regulator activity#GO:0005246;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;calcium ion transmembrane transporter activity#GO:0015085;molecular function inhibitor activity#GO:0140678;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;active transmembrane transporter activity#GO:0022804;monoatomic cation channel activity#GO:0005261;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;channel activity#GO:0015267 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;mitochondrial calcium ion homeostasis#GO:0051560;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;calcium channel complex#GO:0034704;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;monoatomic ion channel complex#GO:0034702;cytoplasm#GO:0005737;inner mitochondrial membrane protein complex#GO:0098800;cation channel complex#GO:0034703;transporter complex#GO:1990351;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000019611.4|UniProtKB=H9H7D6 H9H7D6 ACOX2 PTHR10909:SF344 ELECTRON TRANSPORT OXIDOREDUCTASE PEROXISOMAL ACYL-COENZYME A OXIDASE 2 heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;fatty acid binding#GO:0005504;lipid binding#GO:0008289;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;organic acid binding#GO:0043177 lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;very long-chain fatty acid metabolic process#GO:0000038;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;lipid modification#GO:0030258;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987 microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000002394.4|UniProtKB=F7EZU9 F7EZU9 DTWD1 PTHR15627:SF8 NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 1 catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000011519.3|UniProtKB=A0A5F8GF28 A0A5F8GF28 FARSA PTHR11538:SF40 PHENYLALANYL-TRNA SYNTHETASE PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494 aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000008317.4|UniProtKB=F7FGM5 F7FGM5 MICU2 PTHR12294:SF3 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 2, MITOCHONDRIAL cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;mitochondrial calcium ion homeostasis#GO:0051560;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234 transporter complex#GO:1990351;organelle membrane#GO:0031090;cation channel complex#GO:0034703;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;calcium channel complex#GO:0034704 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000003286.4|UniProtKB=K7E595 K7E595 RFNG PTHR10811:SF1 FRINGE-RELATED BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE RADICAL FRINGE catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646 glycosyltransferase#PC00111;transferase#PC00220 Notch signaling pathway#P00045>Fringe#P01107 MONDO|Ensembl=ENSMODG00000015593.4|UniProtKB=F6ZUE7 F6ZUE7 RETSAT PTHR46091:SF1 BLR7054 PROTEIN ALL-TRANS-RETINOL 13,14-REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;olefinic compound metabolic process#GO:0120254;retinol metabolic process#GO:0042572;terpenoid metabolic process#GO:0006721;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;cellular process#GO:0009987;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000001667.4|UniProtKB=F6SR91 F6SR91 LOC100013073 PTHR15730:SF8 EXPERIMENTAL AUTOIMMUNE PROSTATITIS ANTIGEN 2-RELATED TRPM8 CHANNEL-ASSOCIATED FACTOR HOMOLOG-RELATED binding#GO:0005488;transmembrane transporter binding#GO:0044325;protein binding#GO:0005515 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201;regulation of localization#GO:0032879 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000009552.3|UniProtKB=A0A5F8GGY0 A0A5F8GGY0 KRCC1 PTHR46144:SF1 ZINC FINGER PROTEIN 385B-LIKE U1-TYPE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000003592.3|UniProtKB=F7FBK0 F7FBK0 LRRC61 PTHR18849:SF8 LEUCINE RICH REPEAT PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 61 MONDO|Ensembl=ENSMODG00000010906.4|UniProtKB=F7FIT4 F7FIT4 PTHR11920:SF497 GUANYLYL CYCLASE GUANYLATE CYCLASE cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;lyase activity#GO:0016829;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;enzyme-linked receptor protein signaling pathway#GO:0007167;cGMP biosynthetic process#GO:0006182;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 lyase#PC00144;guanylate cyclase#PC00114 MONDO|Ensembl=ENSMODG00000016044.4|UniProtKB=F6YUJ6 F6YUJ6 FARP2 PTHR45858:SF4 FERM DOMAIN CONTAINING PROTEIN FERM, ARHGEF AND PLECKSTRIN DOMAIN-CONTAINING PROTEIN 2 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 MONDO|Ensembl=ENSMODG00000016937.1|UniProtKB=F6VMV2 F6VMV2 TMEM243 PTHR28603:SF1 TRANSMEMBRANE PROTEIN 243 TRANSMEMBRANE PROTEIN 243 MONDO|Ensembl=ENSMODG00000010074.4|UniProtKB=F6XN82 F6XN82 NRAP PTHR11039:SF39 NEBULIN NEBULIN-RELATED-ANCHORING PROTEIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 tissue development#GO:0009888;multicellular organismal process#GO:0032501;developmental process#GO:0032502;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869;actin filament organization#GO:0007015;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;system development#GO:0048731;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;heart development#GO:0007507;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cardiac muscle cell differentiation#GO:0055007;cellular anatomical entity morphogenesis#GO:0032989;striated muscle tissue development#GO:0014706;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;circulatory system development#GO:0072359;cell differentiation#GO:0030154;actomyosin structure organization#GO:0031032;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002 membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;I band#GO:0031674;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;Z disc#GO:0030018;contractile muscle fiber#GO:0043292 MONDO|Ensembl=ENSMODG00000025182.2|UniProtKB=F7FX86 F7FX86 LOC107652333 PTHR19861:SF0 WD40 REPEAT PROTEIN SWD2 WD REPEAT-CONTAINING PROTEIN 82 chromatin binding#GO:0003682;binding#GO:0005488 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000018173.4|UniProtKB=F7BU33 F7BU33 DRD3 PTHR24248:SF154 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(3) DOPAMINE RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of cell communication#GO:0010648;adrenergic receptor signaling pathway#GO:0071875;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;G protein-coupled dopamine receptor signaling pathway#GO:0007212;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;negative regulation of cellular process#GO:0048523;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Dopamine receptor mediated signaling pathway#P05912>D2/D3/D4#P05965;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Nicotine pharmacodynamics pathway#P06587>DRD2/ DRD3/ DRD4#P06603 MONDO|Ensembl=ENSMODG00000000701.3|UniProtKB=F6WLJ7 F6WLJ7 TPPP PTHR12932:SF18 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;protein binding#GO:0005515 microtubule bundle formation#GO:0001578;positive regulation of cellular component organization#GO:0051130;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular component biogenesis#GO:0044087;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of protein polymerization#GO:0032273;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000048443.1|UniProtKB=K7E3Y4 K7E3Y4 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000016401.4|UniProtKB=F7E8R4 F7E8R4 PFDN4 PTHR21100:SF9 PREFOLDIN SUBUNIT 4 PREFOLDIN SUBUNIT 4 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000014864.5|UniProtKB=F6SDD3 F6SDD3 NOTCH4 PTHR24044:SF471 NOTCH LIGAND FAMILY MEMBER NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 2 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;negative regulation of signaling#GO:0023057;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;signal transduction#GO:0007165;cellular process#GO:0009987;Notch signaling pathway#GO:0007219;negative regulation of Notch signaling pathway#GO:0045746;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000018432.4|UniProtKB=A0A5F8GSC9 A0A5F8GSC9 PCYT1A PTHR10739:SF19 CYTIDYLYLTRANSFERASE CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE A phosphatidylcholine binding#GO:0031210;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;phospholipid binding#GO:0005543;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;cation binding#GO:0043169;lipid binding#GO:0008289;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220 MONDO|Ensembl=ENSMODG00000000877.4|UniProtKB=F7AV62 F7AV62 PTHR23036:SF112 CYTOKINE RECEPTOR INTERLEUKIN-23 RECEPTOR signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;response to peptide#GO:1901652;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021431.4|UniProtKB=F7CB67 F7CB67 IMPA2 PTHR20854:SF29 INOSITOL MONOPHOSPHATASE INOSITOL MONOPHOSPHATASE 2 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000003926.4|UniProtKB=F7FH73 F7FH73 SHQ1 PTHR12967:SF0 PROTEIN SHQ1 HOMOLOG PROTEIN SHQ1 HOMOLOG protein-containing complex organization#GO:0043933;protein-RNA complex assembly#GO:0022618;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000000531.4|UniProtKB=F6XNE1 F6XNE1 ANKRD13C PTHR12447:SF39 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13C protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005299.3|UniProtKB=F7DMM7 F7DMM7 PFN1 PTHR13936:SF14 PROFILIN PROFILIN-1 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin filament polymerization#GO:0030833;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;positive regulation of actin filament bundle assembly#GO:0032233;cellular component organization or biogenesis#GO:0071840;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>Profilin#P00521 MONDO|Ensembl=ENSMODG00000013440.3|UniProtKB=F7G9V5 F7G9V5 PTHR14351:SF1 TESTIS-SPECIFIC SERINE KINASE SUBSTRATE TESTIS-SPECIFIC SERINE KINASE SUBSTRATE reproductive process#GO:0022414;gamete generation#GO:0007276;male gamete generation#GO:0048232;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;spermatogenesis#GO:0007283;developmental process#GO:0032502;sexual reproduction#GO:0019953 organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000005871.4|UniProtKB=A0A5F8GV68 A0A5F8GV68 NAGPA PTHR40446:SF2 N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE localization#GO:0051179;protein secretion#GO:0009306;establishment of localization#GO:0051234;secretion#GO:0046903;intracellular protein localization#GO:0008104;secretion by cell#GO:0032940;establishment of protein localization to extracellular region#GO:0035592;protein transport#GO:0015031;transport#GO:0006810;export from cell#GO:0140352;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein localization to extracellular region#GO:0071692 MONDO|Ensembl=ENSMODG00000006665.5|UniProtKB=F7FFV4 F7FFV4 SDK2 PTHR13817:SF59 TITIN PROTEIN SIDEKICK-2 cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;homophilic cell-cell adhesion#GO:0007156;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cell junction organization#GO:0034330;synapse assembly#GO:0007416;cell adhesion#GO:0007155;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000029857.2|UniProtKB=A0A5F8G4C1 A0A5F8G4C1 PTHR10880:SF48 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000024345.3|UniProtKB=A0A5F8GPN6 A0A5F8GPN6 LOC107650151 PTHR24242:SF248 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 9A2 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000027661.2|UniProtKB=K7E164 K7E164 PTHR33064:SF44 POL PROTEIN RIBONUCLEASE H MONDO|Ensembl=ENSMODG00000006257.5|UniProtKB=F7FE27 F7FE27 PLPPR3 PTHR10165:SF14 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 dephosphorylation#GO:0016311;cell communication#GO:0007154;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular response to stimulus#GO:0051716;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 phosphatase#PC00181;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000000536.4|UniProtKB=A0A5F8GKJ5 A0A5F8GKJ5 CAMK2G PTHR24347:SF398 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT GAMMA protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;calcium/calmodulin-dependent protein kinase activity#GO:0004683;catalytic activity, acting on a protein#GO:0140096;calmodulin binding#GO:0005516;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of biological process#GO:0050789;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of neuronal synaptic plasticity#GO:0048168;regulation of localization#GO:0032879;regulation of synaptic plasticity#GO:0048167;regulation of cell projection organization#GO:0031344;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;regulation of neuron projection development#GO:0010975;regulation of protein localization to membrane#GO:1905475 cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;axon#GO:0030424;postsynaptic density#GO:0014069;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;postsynapse#GO:0098794;neuron projection#GO:0043005 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 MONDO|Ensembl=ENSMODG00000046698.1|UniProtKB=A0A5F8GQ14 A0A5F8GQ14 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000003831.4|UniProtKB=F7GJD2 F7GJD2 AGL PTHR10569:SF2 GLYCOGEN DEBRANCHING ENZYME GLYCOGEN DEBRANCHING ENZYME glucosidase activity#GO:0015926;hydrolase activity#GO:0016787;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;glycosyltransferase activity#GO:0016757;hydrolase activity, acting on glycosyl bonds#GO:0016798;alpha-glucosidase activity#GO:0090599 glycogen catabolic process#GO:0005980;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;generation of precursor metabolites and energy#GO:0006091;catabolic process#GO:0009056;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;glucan catabolic process#GO:0009251;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;polysaccharide catabolic process#GO:0000272;carbohydrate catabolic process#GO:0016052;energy reserve metabolic process#GO:0006112 MONDO|Ensembl=ENSMODG00000038437.1|UniProtKB=A0A5F8GG02 A0A5F8GG02 PTHR15223:SF1 NADH-UBIQUINONE OXIDOREDUCTASE AGGG SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2, MITOCHONDRIAL electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091 catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000001875.4|UniProtKB=F6S5M1 F6S5M1 PARP6 PTHR21328:SF23 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP6 protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;transferase activity#GO:0016740;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;catalytic activity#GO:0003824;protein kinase activator activity#GO:0030295;glycosyltransferase activity#GO:0016757;molecular function regulator activity#GO:0098772;kinase activator activity#GO:0019209;pentosyltransferase activity#GO:0016763 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007 organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;endoplasmic reticulum tubular network#GO:0071782;membrane#GO:0016020;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000038814.1|UniProtKB=F6ZGI4 F6ZGI4 LOC100023784 PTHR48018:SF109 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8U3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025166.3|UniProtKB=A0A5F8H2P0 A0A5F8H2P0 EPG5 PTHR31139:SF4 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG ECTOPIC P GRANULES PROTEIN 5 HOMOLOG lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;lysosome#GO:0005764 MONDO|Ensembl=ENSMODG00000020616.4|UniProtKB=F6ZB31 F6ZB31 COMMD8 PTHR16231:SF0 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 8 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;response to tumor necrosis factor#GO:0034612;response to peptide#GO:1901652;cell communication#GO:0007154;tumor necrosis factor-mediated signaling pathway#GO:0033209;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000038110.1|UniProtKB=A0A5F8H132 A0A5F8H132 PTHR46735:SF3 CALPAIN, SMALL SUBUNIT 1 A-RELATED CALPAIN SMALL SUBUNIT 1A-RELATED catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;caspase complex#GO:0008303;cytoplasm#GO:0005737;peptidase complex#GO:1905368 MONDO|Ensembl=ENSMODG00000008634.3|UniProtKB=F6PGL7 F6PGL7 PTHR18929:SF101 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;biosynthetic process#GO:0009058;protein folding#GO:0006457;response to stimulus#GO:0050896;protein maturation#GO:0051604;gene expression#GO:0010467;cellular response to stress#GO:0033554;metabolic process#GO:0008152;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000016214.4|UniProtKB=H9H6T2 H9H6T2 ASPN PTHR45712:SF2 AGAP008170-PA ASPORIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000011153.4|UniProtKB=F7ANM0 F7ANM0 NT5C2 PTHR12103:SF17 5'-NUCLEOTIDASE DOMAIN-CONTAINING CYTOSOLIC PURINE 5'-NUCLEOTIDASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydrolase activity#GO:0016787;nucleobase-containing compound kinase activity#GO:0019205;5'-nucleotidase activity#GO:0008253;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;transferase activity#GO:0016740;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidase activity#GO:0008252;kinase activity#GO:0016301;phosphatase activity#GO:0016791 carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;IMP metabolic process#GO:0046040;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;purine nucleotide catabolic process#GO:0006195;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 hydrolase#PC00121;nucleotide phosphatase#PC00173;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000037784.1|UniProtKB=A0A5F8HF10 A0A5F8HF10 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000012966.3|UniProtKB=F7DC56 F7DC56 JHY PTHR14726:SF1 JHY PROTEIN HOMOLOG JHY PROTEIN HOMOLOG central nervous system development#GO:0007417;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;system development#GO:0048731;axoneme assembly#GO:0035082;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;head development#GO:0060322;cellular component assembly#GO:0022607;brain development#GO:0007420;multicellular organismal process#GO:0032501;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031 MONDO|Ensembl=ENSMODG00000008244.3|UniProtKB=A0A5F8G2Y6 A0A5F8G2Y6 MKX PTHR11211:SF3 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX HOMEOBOX PROTEIN MOHAWK DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 animal organ development#GO:0048513;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;muscle organ development#GO:0007517;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell development#GO:0048468;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000016481.2|UniProtKB=F6ZDG4 F6ZDG4 CLDN9 PTHR12002:SF42 CLAUDIN CLAUDIN-9 binding#GO:0005488;protein binding#GO:0005515;virus receptor activity#GO:0001618 cellular process#GO:0009987;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840 apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000023819.2|UniProtKB=F6QK61 F6QK61 LOC103102863 PTHR14143:SF1 INTERFERON-INDUCIBLE GTPASE FAMILY MEMBER IMMUNITY-RELATED GTPASE FAMILY, E1-RELATED MONDO|Ensembl=ENSMODG00000006174.4|UniProtKB=F7B502 F7B502 GPR153 PTHR16518:SF5 G-PROTEIN COUPLED RECEPTOR 153, 162 G PROTEIN-COUPLED RECEPTOR 153-RELATED G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037276.1|UniProtKB=A0A5F8H6B8 A0A5F8H6B8 PTHR46612:SF1 XYLOSIDE XYLOSYLTRANSFERASE 1 XYLOSIDE XYLOSYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;UDP-glycosyltransferase activity#GO:0008194 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220 MONDO|Ensembl=ENSMODG00000011744.4|UniProtKB=A0A5F8GLP1 A0A5F8GLP1 CNOT6L PTHR12121:SF35 CARBON CATABOLITE REPRESSOR PROTEIN 4 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408 RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;CCR4-NOT complex#GO:0030014;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000015050.3|UniProtKB=F7FUW0 F7FUW0 LPP PTHR24207:SF0 ZYX102 PROTEIN LIPOMA-PREFERRED PARTNER cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell junction#GO:0030054;actin filament bundle#GO:0032432;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;stress fiber#GO:0001725;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;intracellular membraneless organelle#GO:0043232;cell-substrate junction#GO:0030055;actin cytoskeleton#GO:0015629;actomyosin#GO:0042641 kinase modulator#PC00140 MONDO|Ensembl=ENSMODG00000018559.4|UniProtKB=F7G243 F7G243 ARMC8 PTHR15651:SF7 ARMADILLO REPEAT-CONTAINING PROTEIN 8 ARMADILLO REPEAT-CONTAINING PROTEIN 8 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000007236.4|UniProtKB=F6WC55 F6WC55 INSC PTHR21386:SF0 INSCUTEABLE PROTEIN INSCUTEABLE HOMOLOG cytoskeletal adaptor activity#GO:0008093;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;regulation of cell division#GO:0051302;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938 MONDO|Ensembl=ENSMODG00000014055.3|UniProtKB=F6U8M3 F6U8M3 NFKBID PTHR24124:SF7 ANKYRIN REPEAT FAMILY A NF-KAPPA-B INHIBITOR DELTA regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000000444.4|UniProtKB=F6USL6 F6USL6 JADE3 PTHR13793:SF27 PHD FINGER PROTEINS PROTEIN JADE-3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000008682.4|UniProtKB=F6ZFR7 F6ZFR7 SLC38A6 PTHR22950:SF366 AMINO ACID TRANSPORTER SOLUTE CARRIER FAMILY 38 MEMBER 6 L-amino acid transmembrane transporter activity#GO:0015179;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;neutral L-amino acid transmembrane transporter activity#GO:0015175;amino acid transmembrane transporter activity#GO:0015171 cellular process#GO:0009987;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;localization#GO:0051179;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;amino acid transporter#PC00046 MONDO|Ensembl=ENSMODG00000028787.2|UniProtKB=K7E290 K7E290 PTHR23295:SF5 NUCLEAR RECEPTOR COACTIVATOR 5-RELATED SI:CH211-216L23.2 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000013161.4|UniProtKB=F7ABV3 F7ABV3 IGFBP4 PTHR11551:SF7 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 4 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000018504.4|UniProtKB=F7B3T1 F7B3T1 TASOR2 PTHR16207:SF10 SET DOMAIN-CONTAINING PROTEIN PROTEIN TASOR 2 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000036493.1|UniProtKB=A0A5F8H9E5 A0A5F8H9E5 VCPKMT PTHR14614:SF44 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN N-LYSINE METHYLTRANSFERASE METTL21D catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000008529.4|UniProtKB=F7DHD9 F7DHD9 GAD1 PTHR45677:SF5 GLUTAMATE DECARBOXYLASE-RELATED GLUTAMATE DECARBOXYLASE 1 catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;presynaptic active zone#GO:0048786;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;presynapse#GO:0098793 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 MONDO|Ensembl=ENSMODG00000017268.5|UniProtKB=F6T3P4 F6T3P4 HIVEP2 PTHR45944:SF1 SCHNURRI, ISOFORM F TRANSCRIPTION FACTOR HIVEP2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000011053.5|UniProtKB=F7DSI0 F7DSI0 FBXO2 PTHR12125:SF11 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 2 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000037578.1|UniProtKB=A0A5F8H2K3 A0A5F8H2K3 PTHR16296:SF3 UNCHARACTERIZED HYPOTHALAMUS PROTEIN HT007 COMPLEX I ASSEMBLY FACTOR TMEM126B, MITOCHONDRIAL NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000008051.4|UniProtKB=A0A5F8GXL2 A0A5F8GXL2 DNAJC5B PTHR44027:SF6 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5B chaperone#PC00072 MONDO|Ensembl=ENSMODG00000008180.3|UniProtKB=A0A5F8GKN4 A0A5F8GKN4 MYH10 PTHR45615:SF24 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-10 catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 actin filament-based process#GO:0030029;cytokinesis#GO:0000910;regulation of biological quality#GO:0065008;cytoskeleton-dependent cytokinesis#GO:0061640;regulation of cell shape#GO:0008360;cell cycle process#GO:0022402;cell division#GO:0051301;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell cycle#GO:0007049;regulation of developmental process#GO:0050793;actomyosin structure organization#GO:0031032;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;mitotic cell cycle#GO:0000278;mitotic cell cycle process#GO:1903047;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867 MONDO|Ensembl=ENSMODG00000020735.4|UniProtKB=F7AN85 F7AN85 CENPC PTHR16684:SF11 CENTROMERE PROTEIN C CENTROMERE PROTEIN C nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690 chromosome localization#GO:0050000;cellular component assembly#GO:0022607;cellular process#GO:0009987;attachment of spindle microtubules to kinetochore#GO:0008608;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;organelle fission#GO:0048285;localization#GO:0051179;kinetochore organization#GO:0051383;kinetochore assembly#GO:0051382;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;nuclear division#GO:0000280;organelle localization#GO:0051640;organelle assembly#GO:0070925 membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;kinetochore#GO:0000776 centromere DNA-binding protein#PC00071 MONDO|Ensembl=ENSMODG00000029295.2|UniProtKB=K7E3J1 K7E3J1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000013833.4|UniProtKB=F6SDN0 F6SDN0 PTHR46118:SF4 PROTEIN ABHD11 SN-1-SPECIFIC DIACYLGLYCEROL LIPASE ABHD11 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000009487.3|UniProtKB=A0A5F8GHK2 A0A5F8GHK2 PPP1R36 PTHR21055:SF3 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 36 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 36 phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000003406.2|UniProtKB=A0A5F8GB89 A0A5F8GB89 UBE2G2 PTHR24067:SF154 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G2 ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 response to chemical#GO:0042221;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein K48-linked ubiquitination#GO:0070936;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;ERAD pathway#GO:0036503;protein modification by small protein conjugation or removal#GO:0070647;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Parkinson disease#P00049>Ubc7#P01220 MONDO|Ensembl=ENSMODG00000050289.1|UniProtKB=K7DZF7 K7DZF7 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000006412.3|UniProtKB=F7FD66 F7FD66 PTHR11524:SF12 60S RIBOSOMAL PROTEIN L7 LARGE RIBOSOMAL SUBUNIT PROTEIN UL30 structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488 ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000002362.4|UniProtKB=F7GDL3 F7GDL3 RNF128 PTHR22765:SF30 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF128 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 organelle#GO:0043226;late endosome#GO:0005770;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endosome#GO:0005768;endoplasmic reticulum#GO:0005783 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000019058.4|UniProtKB=A0A5F8GVT6 A0A5F8GVT6 MICU3 PTHR12294:SF10 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 3, MITOCHONDRIAL calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 mitochondrial calcium ion homeostasis#GO:0051560;metal ion transport#GO:0030001;homeostatic process#GO:0042592;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;mitochondrial calcium ion transmembrane transport#GO:0006851;cellular process#GO:0009987;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;calcium channel complex#GO:0034704;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle membrane#GO:0031090;transporter complex#GO:1990351;cation channel complex#GO:0034703;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000000337.4|UniProtKB=A0A5F8GHB4 A0A5F8GHB4 PTHR23120:SF18 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT FAMILY MEMBER 8 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000042741.1|UniProtKB=A0A5F8HGD5 A0A5F8HGD5 AK3 PTHR23359:SF68 NUCLEOTIDE KINASE GTP:AMP PHOSPHOTRANSFERASE AK3, MITOCHONDRIAL catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776 purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 MONDO|Ensembl=ENSMODG00000004905.4|UniProtKB=F7C1R7 F7C1R7 CDH20 PTHR24027:SF84 CADHERIN-23 CADHERIN-20 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell junction organization#GO:0034330;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;cellular component assembly#GO:0022607;cell migration#GO:0016477;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043 anchoring junction#GO:0070161;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000002509.4|UniProtKB=F7B9D0 F7B9D0 ERCC6 PTHR45629:SF15 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6 catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 damaged DNA-binding protein#PC00086 MONDO|Ensembl=ENSMODG00000048364.1|UniProtKB=A0A5F8GQD2 A0A5F8GQD2 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020583.4|UniProtKB=A0A5F8G638 A0A5F8G638 ATP8A1 PTHR24092:SF221 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IA molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 cellular process#GO:0009987;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;biological regulation#GO:0065007;lipid transport#GO:0006869;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000012689.4|UniProtKB=F6VFH7 F6VFH7 PTHR21444:SF14 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 MONDO|Ensembl=ENSMODG00000010255.4|UniProtKB=A0A5F8G8G0 A0A5F8G8G0 CTBP2 PTHR46029:SF3 C-TERMINAL-BINDING PROTEIN C-TERMINAL-BINDING PROTEIN 2 protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713;transcription corepressor activity#GO:0003714;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Wnt signaling pathway#P00057>C-terminal Binding Protein#P01439 MONDO|Ensembl=ENSMODG00000022692.2|UniProtKB=H9H8F3 H9H8F3 FEN1 PTHR11081:SF81 FLAP ENDONUCLEASE FAMILY MEMBER FLAP ENDONUCLEASE 1 RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;binding#GO:0005488;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;DNA endonuclease activity#GO:0004520;metal ion binding#GO:0046872;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;cation binding#GO:0043169;magnesium ion binding#GO:0000287;hydrolase activity#GO:0016787 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 exodeoxyribonuclease#PC00098;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000043766.1|UniProtKB=A0A5F8H5L1 A0A5F8H5L1 PTHR23304:SF189 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000020525.3|UniProtKB=F7ENJ8 F7ENJ8 C6H4orf19 PTHR16106:SF3 CHROMOSOME 4 OPEN READING FRAME 19 PDCD10 AND GCKIII KINASES-ASSOCIATED PROTEIN 1 MONDO|Ensembl=ENSMODG00000002489.4|UniProtKB=A0A5F8H2T9 A0A5F8H2T9 CTNND2 PTHR10372:SF9 PLAKOPHILLIN-RELATED CATENIN DELTA-2 protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;system development#GO:0048731;anatomical structure development#GO:0048856;synapse organization#GO:0050808;postsynapse organization#GO:0099173;dendritic spine morphogenesis#GO:0060997;cell junction organization#GO:0034330;dendritic spine development#GO:0060996;dendrite morphogenesis#GO:0048813;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;dendritic spine organization#GO:0097061;cellular process#GO:0009987;neuron projection development#GO:0031175;cell-cell adhesion#GO:0098609;neuron development#GO:0048666;dendrite development#GO:0016358;generation of neurons#GO:0048699;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;neuron projection organization#GO:0106027;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 cell junction#GO:0030054;adherens junction#GO:0005912;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell-cell junction#GO:0005911;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;postsynapse#GO:0098794 intermediate filament binding protein#PC00130;intermediate filament#PC00129;cytoskeletal protein#PC00085 Cadherin signaling pathway#P00012>P120#P00473 MONDO|Ensembl=ENSMODG00000010901.4|UniProtKB=A0A5F8HAL2 A0A5F8HAL2 RCC1 PTHR45982:SF9 REGULATOR OF CHROMOSOME CONDENSATION REGULATOR OF CHROMOSOME CONDENSATION molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of spindle assembly#GO:0090169;regulation of mitotic spindle organization#GO:0060236;regulation of microtubule-based process#GO:0032886;regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087;regulation of spindle organization#GO:0090224;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of mitotic spindle assembly#GO:1901673;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of organelle assembly#GO:1902115;regulation of mitotic cell cycle#GO:0007346 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000010980.3|UniProtKB=F7APX6 F7APX6 UNC5D PTHR12582:SF5 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5D transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;multicellular organismal process#GO:0032501;cellular process#GO:0009987;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 MONDO|Ensembl=ENSMODG00000009159.3|UniProtKB=F7B0I6 F7B0I6 LOC100618926 PTHR26452:SF361 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000944.4|UniProtKB=F7F7U7 F7F7U7 UBXN4 PTHR46424:SF1 UBX DOMAIN-CONTAINING PROTEIN 4 UBX DOMAIN-CONTAINING PROTEIN 4 response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000007410.4|UniProtKB=F7GKI9 F7GKI9 GTSE1 PTHR21584:SF10 DIFFERENTIAL DISPLAY AND ACTIVATED BY P53 DDA3 /G2 S PHASE EXPRESSED 1 G2 AND S PHASE-EXPRESSED PROTEIN 1 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 p53 pathway#P00059>B99#G04697;p53 pathway#P00059>B99#P04613 MONDO|Ensembl=ENSMODG00000042318.1|UniProtKB=A0A5F8HJH3 A0A5F8HJH3 PTHR45713:SF11 FTP DOMAIN-CONTAINING PROTEIN FUCOLECTIN MONDO|Ensembl=ENSMODG00000050156.1|UniProtKB=A0A5F8HAI6 A0A5F8HAI6 LOC100015831 PTHR11771:SF216 LIPOXYGENASE ARACHIDONATE 12-LIPOXYGENASE, 12S-TYPE-LIKE dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 arachidonate metabolic process#GO:0019369;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;lipid oxidation#GO:0034440;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;icosanoid metabolic process#GO:0006690;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000043280.1|UniProtKB=A0A5F8G863 A0A5F8G863 AGR3 PTHR15337:SF5 ANTERIOR GRADIENT PROTEIN-RELATED ANTERIOR GRADIENT PROTEIN 3 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000009676.4|UniProtKB=A0A5F8H3V1 A0A5F8H3V1 TRUB1 PTHR13767:SF2 TRNA-PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE TRUB1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 pseudouridine synthesis#GO:0001522;mRNA modification#GO:0016556;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;isomerase#PC00135 MONDO|Ensembl=ENSMODG00000006582.3|UniProtKB=F7B7L2 F7B7L2 LOC100024842 PTHR23504:SF34 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 HIPPOCAMPUS ABUNDANT TRANSCRIPT 1 PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000005957.4|UniProtKB=A0A5F8HC83 A0A5F8HC83 LARP4B PTHR22792:SF43 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 4B mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000029038.2|UniProtKB=A0A5F8G7V9 A0A5F8G7V9 FAM120B PTHR15976:SF17 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nuclear receptor-mediated signaling pathway#GO:0141193;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;intracellular receptor signaling pathway#GO:0030522 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000048129.1|UniProtKB=A0A5F8GLJ2 A0A5F8GLJ2 CSKMT PTHR12176:SF83 SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN CITRATE SYNTHASE-LYSINE N-METHYLTRANSFERASE CSKMT, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000018331.4|UniProtKB=F6PSR4 F6PSR4 SEC22A PTHR46258:SF3 LONGIN DOMAIN-CONTAINING PROTEIN VESICLE-TRAFFICKING PROTEIN SEC22A endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000020260.4|UniProtKB=F7CJI3 F7CJI3 ACOT12 PTHR11049:SF3 ACYL COENZYME A THIOESTER HYDROLASE ACETYL-COENZYME A THIOESTERASE catalytic activity#GO:0003824;deacylase activity#GO:0160215;fatty acyl-CoA hydrolase activity#GO:0047617;acyl-CoA hydrolase activity#GO:0016289;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;hydrolase activity#GO:0016787 metabolic process#GO:0008152;acetyl-CoA metabolic process#GO:0006084;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 esterase#PC00097 MONDO|Ensembl=ENSMODG00000024398.1|UniProtKB=F6Z480 F6Z480 PTHR24068:SF177 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 macromolecule metabolic process#GO:0043170;protein K63-linked ubiquitination#GO:0070534;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;post-translational protein modification#GO:0043687;response to stress#GO:0006950;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;protein modification process#GO:0036211;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000014675.4|UniProtKB=F7E7N5 F7E7N5 PTHR16151:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 6 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 6 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;spindle microtubule#GO:0005876;microtubule#GO:0005874 MONDO|Ensembl=ENSMODG00000008156.5|UniProtKB=A0A5F8HDI7 A0A5F8HDI7 SLC3A2 PTHR46673:SF1 4F2 CELL-SURFACE ANTIGEN HEAVY CHAIN AMINO ACID TRANSPORTER HEAVY CHAIN SLC3A2 cellular process#GO:0009987;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;branched-chain amino acid transport#GO:0015803;import into cell#GO:0098657;establishment of localization#GO:0051234;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;amino acid transport#GO:0006865;alanine transport#GO:0032328;carboxylic acid transmembrane transport#GO:1905039;L-leucine transport#GO:0015820;import across plasma membrane#GO:0098739;L-alpha-amino acid transmembrane transport#GO:1902475;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;localization#GO:0051179 apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000023883.1|UniProtKB=F7A843 F7A843 LOC100026980 PTHR28520:SF15 MITOTIC-SPINDLE ORGANIZING PROTEIN 1 MITOTIC-SPINDLE ORGANIZING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;chromosome segregation#GO:0007059;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;nuclear division#GO:0000280;mitotic spindle organization#GO:0007052;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;microtubule nucleation#GO:0007020;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;spindle organization#GO:0007051;chromosome organization#GO:0051276;microtubule polymerization#GO:0046785;mitotic cell cycle process#GO:1903047;microtubule polymerization or depolymerization#GO:0031109;mitotic sister chromatid segregation#GO:0000070;mitotic spindle assembly#GO:0090307;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;mitotic cell cycle#GO:0000278;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000001137.4|UniProtKB=F7D4Q7 F7D4Q7 ATP2B4 PTHR24093:SF435 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 4 ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075 calcium ion homeostasis#GO:0055074;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;regulation of cytosolic calcium ion concentration#GO:0051480;homeostatic process#GO:0042592 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000043638.1|UniProtKB=A0A5F8G964 A0A5F8G964 URM1 PTHR14986:SF4 RURM1 PROTEIN UBIQUITIN-RELATED MODIFIER 1 post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000016951.3|UniProtKB=F6V6E5 F6V6E5 PTHR13947:SF48 GNAT FAMILY N-ACETYLTRANSFERASE N-ACETYLTRANSFERASE 8-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000047421.1|UniProtKB=A0A5F8GFX2 A0A5F8GFX2 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004651.4|UniProtKB=F6UN80 F6UN80 LMCD1 PTHR24211:SF0 LIM DOMAIN-CONTAINING PROTEIN LIM AND CYSTEINE-RICH DOMAINS PROTEIN 1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of biological process#GO:0048518;regulation of calcineurin-NFAT signaling cascade#GO:0070884;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of muscle system process#GO:0090257;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523;regulation of system process#GO:0044057;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of calcium-mediated signaling#GO:0050850;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of calcium-mediated signaling#GO:0050848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000039273.1|UniProtKB=A0A5F8GZR6 A0A5F8GZR6 LOC100032852 PTHR10036:SF11 CD59 GLYCOPROTEIN LY6_PLAUR DOMAIN-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000008862.4|UniProtKB=F7CU79 F7CU79 CCNB2 PTHR10177:SF184 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000008007.2|UniProtKB=F7CLG3 F7CLG3 KCNIP3 PTHR23055:SF165 CALCIUM BINDING PROTEINS CALSENILIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;cation binding#GO:0043169;channel regulator activity#GO:0016247;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transporter regulator activity#GO:0141108;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;ion binding#GO:0043167;small molecule binding#GO:0036094;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;molecular function regulator activity#GO:0098772;sequence-specific double-stranded DNA binding#GO:1990837;ion channel regulator activity#GO:0099106;metal ion binding#GO:0046872;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;potassium channel regulator activity#GO:0015459;calcium ion binding#GO:0005509;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565 regulation of monoatomic ion transport#GO:0043269;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of metal ion transport#GO:0010959;regulation of transmembrane transport#GO:0034762;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of localization#GO:0032879;regulation of transport#GO:0051049;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transporter complex#GO:1990351 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000018319.5|UniProtKB=F6PTK6 F6PTK6 ZNF292 PTHR15507:SF14 ZINC FINGER PROTEIN RLF ZINC FINGER PROTEIN 292 DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000041084.1|UniProtKB=A0A5F8H951 A0A5F8H951 PARP16 PTHR21328:SF2 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP16 enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;kinase activator activity#GO:0019209;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;signal transduction#GO:0007165;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967 endoplasmic reticulum#GO:0005783;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum tubular network#GO:0071782;nucleus#GO:0005634;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle envelope#GO:0031967 MONDO|Ensembl=ENSMODG00000020216.4|UniProtKB=F7FXN7 F7FXN7 PTHR23320:SF175 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE SPANNING 4-DOMAINS A6A cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 MONDO|Ensembl=ENSMODG00000008535.4|UniProtKB=F7DHC5 F7DHC5 MASP1 PTHR24255:SF13 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED MANNAN-BINDING LECTIN SERINE PROTEASE 1 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 defense response to other organism#GO:0098542;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;immune response#GO:0006955;complement activation#GO:0006956;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;humoral immune response#GO:0006959;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;immune system process#GO:0002376;regulation of immune response#GO:0050776 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000021032.3|UniProtKB=F6W0K1 F6W0K1 HSF2BP PTHR15434:SF2 HEAT SHOCK FACTOR 2-BINDING PROTEIN HEAT SHOCK FACTOR 2-BINDING PROTEIN MONDO|Ensembl=ENSMODG00000012864.4|UniProtKB=F7C941 F7C941 NETO2 PTHR24251:SF26 OVOCHYMASE-RELATED NEUROPILIN AND TOLLOID-LIKE PROTEIN 2 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 protein localization to synapse#GO:0035418;regulation of localization#GO:0032879;intracellular protein localization#GO:0008104;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;protein localization to cell periphery#GO:1990778;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cellular process#GO:0009987;regulation of protein localization to membrane#GO:1905475;cellular localization#GO:0051641;localization#GO:0051179;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;protein localization to cell junction#GO:1902414;localization within membrane#GO:0051668;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;protein localization to membrane#GO:0072657;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211 protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000009075.3|UniProtKB=A0A5F8HKJ6 A0A5F8HKJ6 LOC100029952 PTHR24322:SF341 PKSB SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY 16C MEMBER 6 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000029642.2|UniProtKB=K7E1W2 K7E1W2 PTHR46890:SF56 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED OS06G0484800 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000010387.3|UniProtKB=F7AUV1 F7AUV1 PTHR48071:SF29 SRCR DOMAIN-CONTAINING PROTEIN SRCR DOMAIN-CONTAINING PROTEIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000000508.4|UniProtKB=F6Y622 F6Y622 MMAA PTHR23408:SF3 METHYLMALONYL-COA MUTASE METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 mutase#PC00160 MONDO|Ensembl=ENSMODG00000013207.4|UniProtKB=F7EWG6 F7EWG6 FRMD6 PTHR13429:SF11 FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY FERM DOMAIN-CONTAINING PROTEIN 6 molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000050509.1|UniProtKB=A0A5F8G8D5 A0A5F8G8D5 LOC100019224 PTHR24240:SF232 OPSIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;signaling#GO:0023052;cellular response to radiation#GO:0071478;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000014551.4|UniProtKB=A0A5F8GSP7 A0A5F8GSP7 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000012912.4|UniProtKB=F7GCF8 F7GCF8 PTHR16399:SF20 GASDERMIN GASDERMIN-B phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;phosphatidylinositol bisphosphate binding#GO:1902936 response to bacterium#GO:0009617;inflammatory response#GO:0006954;defense response to bacterium#GO:0042742;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419 transporter#PC00227 MONDO|Ensembl=ENSMODG00000005427.4|UniProtKB=A0A5F8HAS3 A0A5F8HAS3 GSTZ1 PTHR42673:SF24 MALEYLACETOACETATE ISOMERASE MALEYLACETOACETATE ISOMERASE isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;glutathione metabolic process#GO:0006749 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 isomerase#PC00135 MONDO|Ensembl=ENSMODG00000021423.4|UniProtKB=F7CBG6 F7CBG6 PSMG2 PTHR12970:SF1 PROTEASOME ASSEMBLY CHAPERONE 2 PROTEASOME ASSEMBLY CHAPERONE 2 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000001041.3|UniProtKB=A0A5F8H100 A0A5F8H100 TTC7A PTHR23083:SF475 TETRATRICOPEPTIDE REPEAT PROTEIN, TPR TETRATRICOPEPTIDE REPEAT PROTEIN 7A macromolecule localization#GO:0033036;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;protein localization to cell periphery#GO:1990778;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;intracellular protein localization#GO:0008104;primary metabolic process#GO:0044238;protein localization to plasma membrane#GO:0072659;phosphorus metabolic process#GO:0006793;protein localization to membrane#GO:0072657;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphatidylinositol phosphate biosynthetic process#GO:0046854;localization within membrane#GO:0051668;cellular localization#GO:0051641;organophosphate biosynthetic process#GO:0090407;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000010419.3|UniProtKB=F7A6T1 F7A6T1 MMP21 PTHR10201:SF340 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-21 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 metabolic process#GO:0008152;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 MONDO|Ensembl=ENSMODG00000011406.4|UniProtKB=F6S5T6 F6S5T6 SLC40A1 PTHR11660:SF47 SOLUTE CARRIER FAMILY 40 MEMBER FERROPORTIN iron ion transmembrane transporter activity#GO:0005381;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;peptide hormone binding#GO:0017046;hormone binding#GO:0042562;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;transition metal ion transport#GO:0000041;iron ion transmembrane transport#GO:0034755;iron ion transport#GO:0006826 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000029221.2|UniProtKB=K7E0J5 K7E0J5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024485.2|UniProtKB=F7EKI8 F7EKI8 CCDC182 PTHR37364:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 182 COILED-COIL DOMAIN-CONTAINING PROTEIN 182 MONDO|Ensembl=ENSMODG00000004375.4|UniProtKB=F6W8W2 F6W8W2 GAL3ST4 PTHR14647:SF57 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSE-3-O-SULFOTRANSFERASE 4 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 transferase#PC00220 MONDO|Ensembl=ENSMODG00000021066.4|UniProtKB=F6V1Z4 F6V1Z4 PTHR20859:SF46 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON GAMMA RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Interferon-gamma signaling pathway#P00035>IFNGR1#P00959;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cytokine receptor#P00866;Interferon-gamma signaling pathway#P00035>IFNGR2#P00957 MONDO|Ensembl=ENSMODG00000002518.4|UniProtKB=F7B965 F7B965 NPPC PTHR12167:SF2 C-TYPE NATRIURETIC PEPTIDE C-TYPE NATRIURETIC PEPTIDE hormone receptor binding#GO:0051427;binding#GO:0005488;signaling receptor binding#GO:0005102;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;cyclic nucleotide biosynthetic process#GO:0009190;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>CNP#G06905;Gonadotropin-releasing hormone receptor pathway#P06664>CNP#P06824;Gonadotropin-releasing hormone receptor pathway#P06664>CNP#G06690 MONDO|Ensembl=ENSMODG00000003342.3|UniProtKB=F7CTJ0 F7CTJ0 LOC100016154 PTHR48018:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 974 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008428.4|UniProtKB=A0A5F8GYZ9 A0A5F8GYZ9 TNFRSF19 PTHR12120:SF1 TNFR-CYS DOMAIN-CONTAINING PROTEIN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 19 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000018219.3|UniProtKB=F6PGM9 F6PGM9 GPRC5D PTHR14511:SF16 G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5 G PROTEIN-COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER D protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;signaling receptor complex#GO:0043235 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000049167.1|UniProtKB=A0A5F8HHT4 A0A5F8HHT4 PTHR36873:SF1 HYPOTHETICAL GENE SUPPORTED BY BC079057 SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 141 MONDO|Ensembl=ENSMODG00000008516.3|UniProtKB=F7D963 F7D963 PTHR33426:SF30 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000014728.3|UniProtKB=A0A5F8H6B4 A0A5F8H6B4 PTHR19331:SF468 SCAVENGER RECEPTOR DOMAIN-CONTAINING ANTIGEN WC1.1 cargo receptor activity#GO:0038024 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000029505.2|UniProtKB=K7E5H1 K7E5H1 SLC27A5 PTHR43107:SF25 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 5 transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;monocarboxylic acid transmembrane transporter activity#GO:0008028;ATP-dependent activity#GO:0140657;carboxylic acid transmembrane transporter activity#GO:0046943;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;macromolecule localization#GO:0033036;steroid metabolic process#GO:0008202;lipid transport#GO:0006869;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;import into cell#GO:0098657;establishment of localization#GO:0051234;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;lipid localization#GO:0010876;oxoacid metabolic process#GO:0043436;monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000012994.3|UniProtKB=F7CRM4 F7CRM4 CSF3 PTHR10511:SF2 GRANULOCYTE COLONY-STIMULATING FACTOR GRANULOCYTE COLONY-STIMULATING FACTOR growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515 regulation of hemopoiesis#GO:1903706;cell communication#GO:0007154;anatomical structure development#GO:0048856;cytokine-mediated signaling pathway#GO:0019221;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;biological regulation#GO:0065007;hemopoiesis#GO:0030097;positive regulation of myeloid cell differentiation#GO:0045639;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;response to peptide#GO:1901652;regulation of myeloid cell differentiation#GO:0045637;response to stimulus#GO:0050896;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;signaling#GO:0023052;cell development#GO:0048468;leukocyte differentiation#GO:0002521;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;mononuclear cell differentiation#GO:1903131;regulation of multicellular organismal development#GO:2000026;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell differentiation#GO:0045597;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of multicellular organismal process#GO:0051239;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000013967.3|UniProtKB=A0A5F8GSF7 A0A5F8GSF7 CCDC12 PTHR31551:SF1 PRE-MRNA-SPLICING FACTOR CWF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 12 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000013763.4|UniProtKB=A0A5F8HDI6 A0A5F8HDI6 RUVBL2 PTHR11093:SF2 RUVB-RELATED REPTIN AND PONTIN RUVB-LIKE 2 ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;cellular component assembly#GO:0022607;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;cellular component biogenesis#GO:0044085;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;protein-containing complex organization#GO:0043933;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;protein-RNA complex organization#GO:0071826;ribonucleoprotein complex biogenesis#GO:0022613;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;protein-RNA complex assembly#GO:0022618 organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;Swr1 complex#GO:0000812;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular anatomical structure#GO:0005622;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Ino80 complex#GO:0031011 MONDO|Ensembl=ENSMODG00000014155.4|UniProtKB=F6X2Y9 F6X2Y9 SCAP PTHR46378:SF1 STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN regulation of steroid biosynthetic process#GO:0050810;regulation of lipid biosynthetic process#GO:0046890;SREBP signaling pathway#GO:0032933;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of lipid metabolic process#GO:0019216;cellular response to stress#GO:0033554 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 MONDO|Ensembl=ENSMODG00000029745.2|UniProtKB=K7E1E8 K7E1E8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000006120.3|UniProtKB=F7EI33 F7EI33 GPR31 PTHR46048:SF7 HYDROXYCARBOXYLIC ACID RECEPTOR 2 12-(S)-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID RECEPTOR G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;negative regulation of defense response#GO:0031348;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000046196.1|UniProtKB=K7E3N9 K7E3N9 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000051246.1|UniProtKB=F6V827 F6V827 LOC100018206 PTHR48002:SF146 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4X2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011144.4|UniProtKB=F7BA62 F7BA62 PTHR11255:SF33 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE KAPPA catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;neutral lipid metabolic process#GO:0006638;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;kinase#PC00137 MONDO|Ensembl=ENSMODG00000009627.4|UniProtKB=F6RDU7 F6RDU7 JOSD1 PTHR13291:SF1 JOSEPHIN 1, 2 JOSEPHIN-1 catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 protein modifying enzyme#PC00260;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000025213.2|UniProtKB=F7BF10 F7BF10 ZBTB5 PTHR24394:SF17 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 5 DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000041425.1|UniProtKB=A0A5F8GS96 A0A5F8GS96 C2H6orf163 PTHR34645:SF1 SIMILAR TO HYPOTHETICAL PROTEIN SIMILAR TO HUMAN CHROMOSOME 6 OPEN READING FRAME 163 MONDO|Ensembl=ENSMODG00000044374.1|UniProtKB=A0A5F8GKJ8 A0A5F8GKJ8 BMF PTHR32014:SF2 BCL-2-MODIFYING FACTOR BCL-2-MODIFYING FACTOR biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of apoptotic process#GO:0043065;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of autophagy#GO:0010506;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of catabolic process#GO:0009895 myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000017597.3|UniProtKB=F7AHX0 F7AHX0 SMAP2 PTHR45705:SF4 FI20236P1 STROMAL MEMBRANE-ASSOCIATED PROTEIN 2 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000004402.4|UniProtKB=F6SVI5 F6SVI5 BSPRY PTHR24103:SF568 E3 UBIQUITIN-PROTEIN LIGASE TRIM B BOX AND SPRY DOMAIN-CONTAINING PROTEIN catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000027733.2|UniProtKB=K7E4E3 K7E4E3 LOC100028348 PTHR19918:SF1 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED FIZZY-RELATED PROTEIN HOMOLOG molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047;binding#GO:0005488 biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000000253.4|UniProtKB=F6WQZ2 F6WQZ2 MANBAL PTHR14409:SF0 MANNOSIDASE, BETA A, LYSOSOMAL-LIKE, MANBAL PROTEIN PROTEIN MANBAL MONDO|Ensembl=ENSMODG00000003015.4|UniProtKB=A0A5F8GNV5 A0A5F8GNV5 BLZF1 PTHR13066:SF2 BASIC LEUCINE ZIPPER NUCLEAR FACTOR 1 BLZF1 PROTEIN GOLGIN-45 protein localization to cell periphery#GO:1990778;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;cellular component organization#GO:0016043;Golgi organization#GO:0007030;Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 MONDO|Ensembl=ENSMODG00000011769.3|UniProtKB=F7C7W5 F7C7W5 PTHR14947:SF23 ZINC FINGER PROTEIN SP4 TRANSCRIPTION FACTOR zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000002708.4|UniProtKB=F7CXU6 F7CXU6 MAP3K13 PTHR23257:SF945 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 13 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000010828.4|UniProtKB=F7BE43 F7BE43 CFAP58 PTHR32083:SF31 CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 58 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000002454.3|UniProtKB=F7DF25 F7DF25 ROPN1L PTHR14952:SF14 ROPPORIN-1-LIKE PROTEIN ROPPORIN-1-LIKE PROTEIN microtubule-based process#GO:0007017;cellular developmental process#GO:0048869;cell maturation#GO:0048469;developmental process#GO:0032502;spermatogenesis#GO:0007283;flagellated sperm motility#GO:0030317;sperm capacitation#GO:0048240;male gamete generation#GO:0048232;developmental maturation#GO:0021700;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;cilium-dependent cell motility#GO:0060285;spermatid development#GO:0007286;cilium or flagellum-dependent cell motility#GO:0001539;sexual reproduction#GO:0019953;cilium movement#GO:0003341;spermatid differentiation#GO:0048515;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell motility#GO:0048870;gamete generation#GO:0007276;microtubule-based movement#GO:0007018;cell differentiation#GO:0030154;germ cell development#GO:0007281;sperm motility#GO:0097722;anatomical structure maturation#GO:0071695;developmental process involved in reproduction#GO:0003006 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929 MONDO|Ensembl=ENSMODG00000000129.4|UniProtKB=A0A5F8H915 A0A5F8H915 RBPJ PTHR10665:SF3 RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 cell communication#GO:0007154;Notch signaling pathway#GO:0007219;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 Alzheimer disease-presenilin pathway#P00004>CSL#P00158;Notch signaling pathway#P00045>Su(H)#P01101;Angiogenesis#P00005>CSL#P00233 MONDO|Ensembl=ENSMODG00000013624.4|UniProtKB=F6UWR8 F6UWR8 PTHR24100:SF64 BUTYROPHILIN BUTYROPHILIN, SUBFAMILY 3, MEMBER A3-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000013296.4|UniProtKB=F6ZJG9 F6ZJG9 PTHR14344:SF3 WD REPEAT PROTEIN TRNA (34-2'-O)-METHYLTRANSFERASE REGULATOR WDR6 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000023902.2|UniProtKB=F7D6L1 F7D6L1 PTHR45755:SF1 FAMILY NOT NAMED PROTON-COUPLED ZINC ANTIPORTER SLC30A5 zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873 homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810 Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;Golgi cis cisterna#GO:0000137;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi stack#GO:0005795;vesicle#GO:0031982;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000013068.4|UniProtKB=A0A5F8GCC5 A0A5F8GCC5 NKD1 PTHR22611:SF2 PROTEIN NAKED CUTICLE PROTEIN NAKED CUTICLE HOMOLOG 1 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 Wnt signaling pathway#P00057>Naked#P01427 MONDO|Ensembl=ENSMODG00000015762.4|UniProtKB=F6ZT65 F6ZT65 PAGR1 PTHR28467:SF1 PAXIP1-ASSOCIATED GLUTAMATE-RICH PROTEIN 1 PAXIP1-ASSOCIATED GLUTAMATE-RICH PROTEIN 1 MONDO|Ensembl=ENSMODG00000000169.3|UniProtKB=F6XA31 F6XA31 CWC15 PTHR12718:SF2 CELL CYCLE CONTROL PROTEIN CWF15 SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000009665.3|UniProtKB=F6SHT3 F6SHT3 ZNRD2 PTHR16537:SF1 SJOEGREN SYNDROME/SCLERODERMA AUTOANTIGEN 1 PROTEIN ZNRD2 MONDO|Ensembl=ENSMODG00000011035.4|UniProtKB=A0A5F8GM34 A0A5F8GM34 PTHR22708:SF0 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 56 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 56 MONDO|Ensembl=ENSMODG00000049042.1|UniProtKB=A0A5F8GCW2 A0A5F8GCW2 PTHR21220:SF0 DNA-DEPENDENT METALLOPROTEASE SPRTN DNA-DEPENDENT METALLOPROTEASE SPRTN metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA synthesis involved in DNA replication#GO:0090592;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000005052.3|UniProtKB=F7AT67 F7AT67 PTHR15268:SF4 THRAP3/BCLAF1 BCL-2-ASSOCIATED TRANSCRIPTION FACTOR 1 transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription coregulator activity#GO:0003712;DNA binding#GO:0003677 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000024121.2|UniProtKB=F6TPB8 F6TPB8 SERTM1 PTHR35660:SF1 SERINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 SERINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000043804.1|UniProtKB=A0A5F8GLD9 A0A5F8GLD9 LOC100013511 PTHR10484:SF210 HISTONE H4 HISTONE H4 structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;chromatin remodeling#GO:0006338;protein-DNA complex assembly#GO:0065004;chromatin organization#GO:0006325 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000044974.1|UniProtKB=A0A5F8GR89 A0A5F8GR89 PTHR24351:SF48 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE BETA-1 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;TORC1 signaling#GO:0038202;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;TOR signaling#GO:0031929;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular response to insulin stimulus#GO:0032869 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142;PI3 kinase pathway#P00048>S6K#P01194;CCKR signaling map#P06959>p70S6K1#P07031;p53 pathway by glucose deprivation#P04397>S6K#P04636;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888 MONDO|Ensembl=ENSMODG00000016941.3|UniProtKB=F6VMH3 F6VMH3 PTHR11960:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 1B translation factor activity#GO:0180051;binding#GO:0005488;nucleic acid binding#GO:0003676;translation initiation factor activity#GO:0003743;RNA binding#GO:0003723 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000040049.1|UniProtKB=A0A5F8G9W0 A0A5F8G9W0 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009679.4|UniProtKB=F6SH18 F6SH18 SSH2 PTHR45864:SF3 SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG PROTEIN PHOSPHATASE SLINGSHOT HOMOLOG 2 protein binding#GO:0005515;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;binding#GO:0005488;actin binding#GO:0003779;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on ester bonds#GO:0016788 regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin filament organization#GO:0110053;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195 Cytoskeletal regulation by Rho GTPase#P00016>Slingshot#P00509 MONDO|Ensembl=ENSMODG00000022835.2|UniProtKB=H9H9J3 H9H9J3 PTHR11783:SF9 SULFOTRANSFERASE SULT SULFOTRANSFERASE 2B1 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000012116.2|UniProtKB=A0A5F8G5J5 A0A5F8G5J5 PTHR10809:SF155 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;developmental process#GO:0032502;endoplasmic reticulum membrane organization#GO:0090158;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;multicellular organismal process#GO:0032501 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000040044.1|UniProtKB=A0A5F8HAN6 A0A5F8HAN6 PTHR11426:SF247 HISTONE H3 HISTONE H3.3C-LIKE metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromosome localization#GO:0050000;organelle assembly#GO:0070925;nuclear division#GO:0000280;organelle localization#GO:0051640;kinetochore assembly#GO:0051382;localization#GO:0051179;kinetochore organization#GO:0051383;organelle fission#GO:0048285;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;mitotic metaphase chromosome alignment#GO:0007080;protein-containing complex assembly#GO:0065003;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 MONDO|Ensembl=ENSMODG00000014214.4|UniProtKB=A0A5F8G824 A0A5F8G824 JADE2 PTHR13793:SF84 PHD FINGER PROTEINS E3 UBIQUITIN-PROTEIN LIGASE JADE-2 chromatin-protein adaptor activity#GO:0140463;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000003579.4|UniProtKB=A0A5F8H6Q6 A0A5F8H6Q6 RASA3 PTHR10194:SF53 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 3 GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000022842.3|UniProtKB=H9H9N2 H9H9N2 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000043255.1|UniProtKB=A0A5F8G7J2 A0A5F8G7J2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003813.4|UniProtKB=F6YW89 F6YW89 NEIL3 PTHR22993:SF10 FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE ENDONUCLEASE 8-LIKE 3 catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;DNA N-glycosylase activity#GO:0019104 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA glycosylase#PC00010 MONDO|Ensembl=ENSMODG00000002703.4|UniProtKB=F7CY11 F7CY11 SULT1C3 PTHR11783:SF77 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1C3 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000021103.3|UniProtKB=F6UHZ3 F6UHZ3 TSPAN7 PTHR19282:SF257 TETRASPANIN TETRASPANIN-7 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007737.4|UniProtKB=A0A5F8HH90 A0A5F8HH90 SCUBE2 PTHR24046:SF3 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 2 cellular developmental process#GO:0048869;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cellular response to growth factor stimulus#GO:0071363;smoothened signaling pathway#GO:0007224;animal gross anatomical part developmental process#GO:0160108;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell development#GO:0048468;response to endogenous stimulus#GO:0009719;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 extracellular matrix glycoprotein#PC00100 MONDO|Ensembl=ENSMODG00000009561.4|UniProtKB=F7BJH0 F7BJH0 PLEKHG3 PTHR45924:SF4 FI17866P1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 3 protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of establishment or maintenance of cell polarity#GO:0032878;regulation of biological process#GO:0050789 MONDO|Ensembl=ENSMODG00000020277.4|UniProtKB=F7C0T2 F7C0T2 C5orf34 PTHR34531:SF1 ZGC:153352 CHROMOSOME 5 OPEN READING FRAME 34 MONDO|Ensembl=ENSMODG00000045173.1|UniProtKB=A0A5F8GEF9 A0A5F8GEF9 PTHR11523:SF47 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-3 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671 sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;export from cell#GO:0140352;import across plasma membrane#GO:0098739;inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;potassium ion homeostasis#GO:0055075;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cation-transporting ATPase complex#GO:0090533 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000000264.3|UniProtKB=F6WB97 F6WB97 RALB PTHR24070:SF199 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAL-B ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 Ras Pathway#P04393>Ral#P04550 MONDO|Ensembl=ENSMODG00000001131.4|UniProtKB=A0A5F8GU03 A0A5F8GU03 THSD7B PTHR11311:SF7 SPONDIN THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 7B cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament-based process#GO:0030029 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000005935.4|UniProtKB=F6WWM0 F6WWM0 CEP55 PTHR31838:SF1 CENTROSOMAL PROTEIN OF 55 KDA CENTROSOMAL PROTEIN OF 55 KDA protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 membrane organization#GO:0061024;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;cell division#GO:0051301;mitotic cytokinetic process#GO:1902410;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinesis#GO:0000910;cytokinetic process#GO:0032506 midbody#GO:0030496;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000017602.5|UniProtKB=A0A5F8GWC8 A0A5F8GWC8 EPB41L2 PTHR23280:SF17 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 2 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 Dopamine receptor mediated signaling pathway#P05912>EPB41L2#P05952;Nicotine pharmacodynamics pathway#P06587>EPB41L2#P06598;Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 MONDO|Ensembl=ENSMODG00000003531.3|UniProtKB=F7GBT1 F7GBT1 PTHR48018:SF55 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027528.2|UniProtKB=K7E0N7 K7E0N7 PTHR23037:SF51 CYTOKINE RECEPTOR FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048901.1|UniProtKB=F6Z4P4 F6Z4P4 LOC100019374 PTHR48002:SF159 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4A16 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005732.4|UniProtKB=F6QEE5 F6QEE5 BRINP2 PTHR15564:SF8 MACPF DOMAIN-CONTAINING PROTEIN BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 2 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of mitotic cell cycle#GO:0007346;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;system development#GO:0048731;anatomical structure development#GO:0048856;nervous system development#GO:0007399;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;multicellular organism development#GO:0007275;negative regulation of cell cycle#GO:0045786;neuron differentiation#GO:0030182;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;response to oxygen-containing compound#GO:1901700;generation of neurons#GO:0048699;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108 neuron projection#GO:0043005;cell body#GO:0044297;cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000015761.4|UniProtKB=F6ZT50 F6ZT50 DPYSL5 PTHR11647:SF58 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 5 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;dihydropyrimidinase activity#GO:0004157;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;pyrimidine nucleobase catabolic process#GO:0006208;primary metabolic process#GO:0044238;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;pyrimidine nucleobase metabolic process#GO:0006206;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRAM#P00330;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 MONDO|Ensembl=ENSMODG00000016212.4|UniProtKB=F7FXW6 F7FXW6 GOLIM4 PTHR22909:SF22 GOLGI INTEGRAL MEMBRANE PROTEIN 4 GOLGI INTEGRAL MEMBRANE PROTEIN 4 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000009994.4|UniProtKB=F6USC7 F6USC7 DCAF7 PTHR19919:SF0 WD REPEAT CONTAINING PROTEIN DDB1- AND CUL4-ASSOCIATED FACTOR 7 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000005152.4|UniProtKB=F7EPX0 F7EPX0 CDH24 PTHR24027:SF272 CADHERIN-23 CADHERIN-24 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 anatomical structure development#GO:0048856;cell adhesion#GO:0007155;cell junction organization#GO:0034330;cell morphogenesis#GO:0000902;cell motility#GO:0048870;anatomical structure morphogenesis#GO:0009653;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell-cell junction assembly#GO:0007043;cellular component assembly#GO:0022607;cell migration#GO:0016477;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609 cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000023444.2|UniProtKB=F6VNK9 F6VNK9 TENT5A PTHR12974:SF25 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5A transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;positive regulation of biological process#GO:0048518;RNA stabilization#GO:0043489;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of RNA catabolic process#GO:1902369;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 MONDO|Ensembl=ENSMODG00000015514.3|UniProtKB=F6VYP5 F6VYP5 GALNT14 PTHR11675:SF8 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 14 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000003986.3|UniProtKB=F7DST4 F7DST4 PSMD12 PTHR10855:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;cytoplasm#GO:0005737;proteasome complex#GO:0000502;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 MONDO|Ensembl=ENSMODG00000017772.3|UniProtKB=F7DJY4 F7DJY4 PTHR10903:SF199 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000015354.4|UniProtKB=F6WXL8 F6WXL8 FEV PTHR11849:SF203 ETS PROTEIN FEV DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 MONDO|Ensembl=ENSMODG00000014830.2|UniProtKB=F7CHZ0 F7CHZ0 PTHR26453:SF234 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6A2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014453.3|UniProtKB=F7ATA8 F7ATA8 CRYAB PTHR45640:SF5 HEAT SHOCK PROTEIN HSP-12.2-RELATED ALPHA-CRYSTALLIN B CHAIN regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to heat#GO:0009408;response to stress#GO:0006950;biosynthetic process#GO:0009058;biological regulation#GO:0065007;response to temperature stimulus#GO:0009266;negative regulation of apoptotic process#GO:0043066;gene expression#GO:0010467;protein maturation#GO:0051604;protein refolding#GO:0042026;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;protein folding#GO:0006457;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 MONDO|Ensembl=ENSMODG00000020768.5|UniProtKB=F6ZA53 F6ZA53 PCDH10 PTHR24028:SF0 CADHERIN-87A PROTOCADHERIN-10 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000028501.2|UniProtKB=K7E4I6 K7E4I6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000013173.3|UniProtKB=F6ZLM8 F6ZLM8 FAM174B PTHR28607:SF3 EXPRESSED PROTEIN MEMBRANE PROTEIN FAM174B MONDO|Ensembl=ENSMODG00000001262.4|UniProtKB=F7CJ17 F7CJ17 RASGEF1A PTHR23113:SF172 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1A guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000029530.2|UniProtKB=K7E4V1 K7E4V1 PTHR19446:SF479 REVERSE TRANSCRIPTASES RNA-DIRECTED DNA POLYMERASE viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000013729.4|UniProtKB=F6X5N0 F6X5N0 SCN1B PTHR10546:SF2 SODIUM CHANNEL SUBUNIT BETA-1 AND 3 SODIUM CHANNEL REGULATORY SUBUNIT BETA-1 molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247;protein binding#GO:0005515;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;binding#GO:0005488 localization#GO:0051179;monoatomic cation transport#GO:0006812;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;regulation of heart contraction#GO:0008016;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;striated muscle contraction#GO:0006941;actin-mediated cell contraction#GO:0070252;heart contraction#GO:0060047;system process#GO:0003008;cardiac muscle cell contraction#GO:0086003;establishment of localization#GO:0051234;transport#GO:0006810;muscle contraction#GO:0006936;regulation of system process#GO:0044057;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;actin filament-based movement#GO:0030048;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;heart process#GO:0003015;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;action potential#GO:0001508;muscle system process#GO:0003012;regulation of membrane potential#GO:0042391;regulation of multicellular organismal process#GO:0051239;monoatomic cation transmembrane transport#GO:0098655;cardiac muscle cell action potential involved in contraction#GO:0086002;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;cation channel complex#GO:0034703;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000004498.4|UniProtKB=F6VAA0 F6VAA0 PCF11 PTHR15921:SF3 PRE-MRNA CLEAVAGE COMPLEX II PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;enzyme binding#GO:0019899;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA binding#GO:0003723;RNA polymerase binding#GO:0070063;RNA polymerase core enzyme binding#GO:0043175 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription termination#GO:0006353;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;termination of RNA polymerase II transcription#GO:0006369;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000011729.3|UniProtKB=F7FSS6 F7FSS6 OTUD7A PTHR13367:SF9 UBIQUITIN THIOESTERASE OTU DOMAIN-CONTAINING PROTEIN 7A catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;catabolic process#GO:0009056 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000004331.4|UniProtKB=A0A5F8HAF3 A0A5F8HAF3 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020972.2|UniProtKB=F6S609 F6S609 HMGN1 PTHR23087:SF12 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-14 chromatin binding#GO:0003682;binding#GO:0005488 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000045161.1|UniProtKB=A0A5F8GT75 A0A5F8GT75 NAA10 PTHR23091:SF268 N-TERMINAL ACETYLTRANSFERASE N-ALPHA-ACETYLTRANSFERASE 10 protein N-acyltransferase activity#GO:0140186;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;N-acetyltransferase activity#GO:0008080;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 acetyltransferase complex#GO:1902493;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein acetyltransferase complex#GO:0031248;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000021110.4|UniProtKB=F6U2X4 F6U2X4 CYBB PTHR11972:SF60 NADPH OXIDASE NADPH OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 response to stress#GO:0006950;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;response to stimulus#GO:0050896;superoxide metabolic process#GO:0006801;defense response#GO:0006952 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 metabolite interconversion enzyme#PC00262;oxidase#PC00175 MONDO|Ensembl=ENSMODG00000015747.3|UniProtKB=F7AHP2 F7AHP2 SSR3 PTHR13399:SF2 TRANSLOCON-ASSOCIATED PROTEIN TRAP , GAMMA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT GAMMA endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000017799.4|UniProtKB=F7CFL0 F7CFL0 NUS1 PTHR21528:SF0 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 transferase activity#GO:0016740;catalytic activity#GO:0003824;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;organophosphate metabolic process#GO:0019637;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 MONDO|Ensembl=ENSMODG00000005825.4|UniProtKB=F6U1Y6 F6U1Y6 CA3 PTHR18952:SF127 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 3 catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 response to hypoxia#GO:0001666;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to abiotic stimulus#GO:0009628;cellular response to hypoxia#GO:0071456;response to stress#GO:0006950;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000014585.4|UniProtKB=F7AS66 F7AS66 YPEL2 PTHR13848:SF3 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 2 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000000537.4|UniProtKB=F6XN03 F6XN03 TRPC6 PTHR10117:SF7 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 6 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488 transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;sexual reproduction#GO:0019953;fertilization#GO:0009566;reproductive process#GO:0022414;metal ion transport#GO:0030001;homeostatic process#GO:0042592;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cytosolic calcium ion concentration#GO:0051480;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;single fertilization#GO:0007338;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987 cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 MONDO|Ensembl=ENSMODG00000006265.4|UniProtKB=F7FE07 F7FE07 MKRN2OS PTHR33963:SF2 MKRN2 OPPOSITE STRAND PROTEIN MKRN2 OPPOSITE STRAND PROTEIN MONDO|Ensembl=ENSMODG00000007498.3|UniProtKB=F6YX95 F6YX95 UCP2 PTHR45618:SF1 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED DICARBOXYLATE CARRIER SLC25A8 proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;adaptive thermogenesis#GO:1990845;mitochondrial transmembrane transport#GO:1990542;homeostatic process#GO:0042592;mitochondrial transport#GO:0006839;response to stimulus#GO:0050896;response to cold#GO:0009409;response to abiotic stimulus#GO:0009628;multicellular organismal-level homeostasis#GO:0048871;establishment of localization#GO:0051234;transport#GO:0006810;temperature homeostasis#GO:0001659;intracellular transport#GO:0046907;response to temperature stimulus#GO:0009266;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;response to stress#GO:0006950 mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000037288.1|UniProtKB=A0A5F8H4N4 A0A5F8H4N4 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000000273.4|UniProtKB=F6WB47 F6WB47 NOL12 PTHR14577:SF0 NUCLEOLAR PROTEIN 12 NUCLEOLAR PROTEIN 12 binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;RNA binding#GO:0003723 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000017794.4|UniProtKB=F7CZ87 F7CZ87 ZC3H12A PTHR12876:SF10 N4BP1-RELATED ENDORIBONUCLEASE ZC3H12A catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;nucleus#GO:0005634 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000011345.3|UniProtKB=A0A5F8G9M5 A0A5F8G9M5 OR51M1 PTHR26450:SF44 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51M1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000692.1|UniProtKB=F6WLV8 F6WLV8 MMP8 PTHR10201:SF337 MATRIX METALLOPROTEINASE MATRIX METALLOPEPTIDASE 8 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 catabolic process#GO:0009056;cellular process#GO:0009987;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;metabolic process#GO:0008152 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000000250.4|UniProtKB=A0A5F8GK88 A0A5F8GK88 USP54 PTHR22975:SF5 UBIQUITIN SPECIFIC PROTEINASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 54 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000046583.1|UniProtKB=F7FKD1 F7FKD1 LOC100025413 PTHR26454:SF72 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C74 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000378.3|UniProtKB=F6R8U5 F6R8U5 MCOLN3 PTHR12127:SF5 MUCOLIPIN MUCOLIPIN-3 monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;gated channel activity#GO:0022836 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000045676.1|UniProtKB=A0A5F8G7R8 A0A5F8G7R8 PTHR48424:SF3 DYNEIN LIGHT CHAIN-RELATED DYNEIN LIGHT CHAIN Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000036613.1|UniProtKB=A0A5F8GN55 A0A5F8GN55 VN2R583 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000011348.4|UniProtKB=A0A5F8G650 A0A5F8G650 LRCH1 PTHR16083:SF10 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT AND CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN 1 regulation of cell migration#GO:0030334;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;regulation of locomotion#GO:0040012;negative regulation of locomotion#GO:0040013;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;negative regulation of immune system process#GO:0002683;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to chemokine#GO:1990868;response to peptide#GO:1901652;regulation of cell motility#GO:2000145;regulation of lymphocyte migration#GO:2000401;cellular response to chemokine#GO:1990869;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of leukocyte migration#GO:0002685;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000008942.4|UniProtKB=F7GD50 F7GD50 PXDC1 PTHR31433:SF0 PX DOMAIN-CONTAINING PROTEIN 1 PX DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000005870.4|UniProtKB=F6R392 F6R392 EGF PTHR46513:SF5 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED PRO-EPIDERMAL GROWTH FACTOR signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083 positive regulation of MAPK cascade#GO:0043410;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGF#P00549;Gonadotropin-releasing hormone receptor pathway#P06664>EGF#P06745 MONDO|Ensembl=ENSMODG00000006064.4|UniProtKB=A0A5F8G4N6 A0A5F8G4N6 DNM2 PTHR11566:SF23 DYNAMIN DYNAMIN-2 cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;microtubule binding#GO:0008017;GTPase activity#GO:0003924;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;protein binding#GO:0005515 endocytosis#GO:0006897;establishment of organelle localization#GO:0051656;synaptic vesicle endocytosis#GO:0048488;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of vesicle localization#GO:0051650;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;synaptic vesicle localization#GO:0097479;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987;organelle organization#GO:0006996;receptor internalization#GO:0031623;synaptic vesicle transport#GO:0048489;receptor-mediated endocytosis#GO:0006898;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810 microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell junction#GO:0030054;cytoskeleton#GO:0005856;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000003565.4|UniProtKB=F7G139 F7G139 SDSL PTHR48078:SF16 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED SERINE DEHYDRATASE-LIKE catalytic activity#GO:0003824;lyase activity#GO:0016829 amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;branched-chain amino acid biosynthetic process#GO:0009082;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 lyase#PC00144;dehydratase#PC00091 MONDO|Ensembl=ENSMODG00000051559.1|UniProtKB=K7E0F2 K7E0F2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000017189.1|UniProtKB=F6XXQ9 F6XXQ9 SSNA1 PTHR28661:SF3 SJOEGREN SYNDROME NUCLEAR AUTOANTIGEN 1 MICROTUBULE NUCLEATION FACTOR SSNA1 cellular developmental process#GO:0048869;developmental growth#GO:0048589;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;anatomical structure development#GO:0048856;system development#GO:0048731;developmental cell growth#GO:0048588;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell growth#GO:0016049;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;growth#GO:0040007;plasma membrane bounded cell projection morphogenesis#GO:0120039;axon extension#GO:0048675;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;neuron development#GO:0048666;neuron projection extension#GO:1990138;developmental growth involved in morphogenesis#GO:0060560;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;axon#GO:0030424;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005 MONDO|Ensembl=ENSMODG00000002241.4|UniProtKB=F7DFG2 F7DFG2 CYP1A1 PTHR24299:SF56 CYTOCHROME P450 FAMILY 1 CYTOCHROME P450 1A catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 regulation of biological quality#GO:0065008;steroid catabolic process#GO:0006706;estrogen metabolic process#GO:0008210;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;xenobiotic metabolic process#GO:0006805;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;secondary metabolic process#GO:0019748;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;cellular response to xenobiotic stimulus#GO:0071466;biological regulation#GO:0065007;steroid metabolic process#GO:0008202;hormone metabolic process#GO:0042445;response to chemical#GO:0042221;cellular process#GO:0009987;lipid catabolic process#GO:0016042 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000041058.1|UniProtKB=A0A5F8HCY2 A0A5F8HCY2 PTHR13531:SF5 GEO07735P1-RELATED-RELATED TRANSMEMBRANE PROTEIN 216 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 cilium#GO:0005929;ciliary transition zone#GO:0035869;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000024866.2|UniProtKB=F6ZI63 F6ZI63 TNP1 PTHR17486:SF0 SPERMATID NUCLEAR TRANSITION PROTEIN 1 SPERMATID NUCLEAR TRANSITION PROTEIN 1 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;cellular component organization#GO:0016043;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;chromatin remodeling#GO:0006338;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154;spermatid development#GO:0007286;sexual reproduction#GO:0019953;spermatid differentiation#GO:0048515;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;cellular process#GO:0009987;organelle organization#GO:0006996;chromatin organization#GO:0006325;male gamete generation#GO:0048232;spermatogenesis#GO:0007283;developmental process#GO:0032502;nucleus organization#GO:0006997;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000039397.1|UniProtKB=A0A5F8GID0 A0A5F8GID0 PTHR16502:SF0 KERATINOCYTE-ASSOCIATED TRANSMEMBRANE PROTEIN 2 KERATINOCYTE-ASSOCIATED TRANSMEMBRANE PROTEIN 2 MONDO|Ensembl=ENSMODG00000027395.2|UniProtKB=K7DZY4 K7DZY4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000045880.1|UniProtKB=A0A5F8HB79 A0A5F8HB79 PTHR44337:SF10 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM18 cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000019805.4|UniProtKB=H9H7H3 H9H7H3 PPP1R2 PTHR12398:SF20 PROTEIN PHOSPHATASE INHIBITOR PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 2 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 phosphatase inhibitor#PC00183 MONDO|Ensembl=ENSMODG00000000242.4|UniProtKB=H9H5U9 H9H5U9 TMEM198 PTHR31247:SF7 TRANSMEMBRANE PROTEIN 198 FAMILY MEMBER TRANSMEMBRANE PROTEIN 198 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of canonical Wnt signaling pathway#GO:0060828 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000022797.2|UniProtKB=A0A5F8GS16 A0A5F8GS16 PTHR24073:SF1096 DRAB5-RELATED RAS-RELATED PROTEIN RAB-1B ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 catabolic process#GO:0009056;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 cell body#GO:0044297;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000042470.1|UniProtKB=A0A5F8GU46 A0A5F8GU46 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012706.4|UniProtKB=F6UY61 F6UY61 PTHR19944:SF108 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DRB1 BETA CHAIN protein-containing complex binding#GO:0044877;binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823 immune system process#GO:0002376;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;regulation of lymphocyte activation#GO:0051249;positive regulation of leukocyte activation#GO:0002696;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of cell-cell adhesion#GO:0022409;cellular component biogenesis#GO:0044085;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;regulation of immune response#GO:0050776;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;positive regulation of cell adhesion#GO:0045785;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155 endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;late endosome#GO:0005770;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505 major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000005718.3|UniProtKB=F6U3I6 F6U3I6 ALOX15 PTHR11771:SF33 LIPOXYGENASE POLYUNSATURATED FATTY ACID LIPOXYGENASE ALOX15 oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;lipid modification#GO:0030258;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;arachidonate metabolic process#GO:0019369;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944 oxidoreductase#PC00176;oxygenase#PC00177 Gonadotropin-releasing hormone receptor pathway#P06664>12-LO#P06815;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Lipoxygenase#P00830 MONDO|Ensembl=ENSMODG00000014962.3|UniProtKB=F7CGX2 F7CGX2 LRRC8E PTHR45752:SF8 LEUCINE-RICH REPEAT-CONTAINING VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8E monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253 transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;establishment of localization#GO:0051234;nitrogen compound transport#GO:0071705;aspartate transmembrane transport#GO:0015810;dicarboxylic acid transport#GO:0006835;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;monoatomic anion transport#GO:0006820;cellular response to stimulus#GO:0051716;carbohydrate derivative transport#GO:1901264;regulation of cellular process#GO:0050794;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;carboxylic acid transmembrane transport#GO:1905039;amino acid transport#GO:0006865;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;acidic amino acid transport#GO:0015800;import into cell#GO:0098657;cellular process#GO:0009987;signal transduction#GO:0007165;monoatomic anion transmembrane transport#GO:0098656;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;response to stimulus#GO:0050896;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017409.4|UniProtKB=F7AJH3 F7AJH3 ARFGEF3 PTHR10663:SF344 GUANYL-NUCLEOTIDE EXCHANGE FACTOR BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 3 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000006082.3|UniProtKB=F7FEJ3 F7FEJ3 monDomV1R1221 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016017.4|UniProtKB=F6UR47 F6UR47 TRIM10 PTHR24103:SF696 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 10 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 response to stimulus#GO:0050896;defense response to other organism#GO:0098542;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000003148.3|UniProtKB=F6WEL2 F6WEL2 SNTB2 PTHR10554:SF8 SYNTROPHIN BETA-2-SYNTROPHIN plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000029120.2|UniProtKB=K7E3Z7 K7E3Z7 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000028869.2|UniProtKB=K7E581 K7E581 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000011326.4|UniProtKB=A0A5F8HHY9 A0A5F8HHY9 VPS13C PTHR16166:SF125 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13C phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215 process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;lipid localization#GO:0010876;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;macroautophagy#GO:0016236;lipid transport#GO:0006869;autophagy#GO:0006914;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;vesicle#GO:0031982;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;outer membrane#GO:0019867;endosome membrane#GO:0010008;endosome#GO:0005768;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000000717.4|UniProtKB=F6SFM2 F6SFM2 LOC100618736 PTHR24377:SF980 IP01015P-RELATED ZINC FINGER PROTEIN 420 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017596.6|UniProtKB=H9H739 H9H739 YBX2 PTHR11544:SF61 COLD SHOCK DOMAIN CONTAINING PROTEINS Y-BOX-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000001367.4|UniProtKB=F7FVV8 F7FVV8 CPSF4 PTHR23102:SF18 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4 mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;nucleus#GO:0005634 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000004052.4|UniProtKB=A0A5F8GC48 A0A5F8GC48 RASGEF1C PTHR23113:SF186 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1C guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000015878.5|UniProtKB=F7B459 F7B459 PPP1R18 PTHR21685:SF0 TON-B BOX DOMAIN PHOSTENSIN MONDO|Ensembl=ENSMODG00000006288.3|UniProtKB=F7CAI4 F7CAI4 RNF19A PTHR11685:SF111 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF19A catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000023665.3|UniProtKB=A0A5F8HB15 A0A5F8HB15 LOC103094147 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000051244.1|UniProtKB=A0A5F8GJI5 A0A5F8GJI5 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000025040.1|UniProtKB=F6W7W9 F6W7W9 LOC100017285 PTHR23329:SF1 TUFTELIN-INTERACTING PROTEIN 11-RELATED TUFTELIN-INTERACTING PROTEIN 11 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component disassembly#GO:0022411;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;protein-containing complex disassembly#GO:0032984 nucleus#GO:0005634;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000050679.1|UniProtKB=A0A5F8HF87 A0A5F8HF87 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000020172.4|UniProtKB=F7GI33 F7GI33 LPXN PTHR24216:SF23 PAXILLIN-RELATED LEUPAXIN protein sequestering activity#GO:0140311;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular sequestering activity#GO:0140313 negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of B cell receptor signaling pathway#GO:0050855;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;negative regulation of signaling#GO:0023057 intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;cell-cell junction#GO:0005911;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell-substrate junction#GO:0030055;cell projection#GO:0042995;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 VEGF signaling pathway#P00056>Paxillin#P01418;Angiogenesis#P00005>Paxillin#P00194 MONDO|Ensembl=ENSMODG00000014627.3|UniProtKB=F6YPT2 F6YPT2 PTHR23266:SF345 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN LAMBDA CONSTANT 6 binding#GO:0005488;antigen binding#GO:0003823 immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000010861.4|UniProtKB=F7FW94 F7FW94 RCBTB1 PTHR22870:SF224 REGULATOR OF CHROMOSOME CONDENSATION RCC1 AND BTB DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000039201.1|UniProtKB=A0A5F8HK46 A0A5F8HK46 PTHR46595:SF2 60S RIBOSOMAL PROTEIN L34 LARGE RIBOSOMAL SUBUNIT PROTEIN EL34 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000002624.4|UniProtKB=F7FUF8 F7FUF8 ECEL1 PTHR11733:SF195 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED ENDOTHELIN-CONVERTING ENZYME-LIKE 1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 MONDO|Ensembl=ENSMODG00000050239.1|UniProtKB=A0A5F8G7R9 A0A5F8G7R9 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000043375.1|UniProtKB=F6ZKN1 F6ZKN1 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000014201.4|UniProtKB=A0A5F8GHK5 A0A5F8GHK5 CDKL3 PTHR24056:SF177 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 3 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000020066.2|UniProtKB=F7GIK5 F7GIK5 LOC100617928 PTHR48018:SF129 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 9G4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000046663.1|UniProtKB=A0A5F8GEB1 A0A5F8GEB1 LOC100619424 PTHR24390:SF290 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 184 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020996.4|UniProtKB=F6RK02 F6RK02 LTN1 PTHR12389:SF0 ZINC FINGER PROTEIN 294 E3 UBIQUITIN-PROTEIN LIGASE LISTERIN aminoacyltransferase activity#GO:0016755;ribosomal large subunit binding#GO:0043023;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ribosome binding#GO:0043022;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488 translation#GO:0006412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;rescue of stalled cytosolic ribosome#GO:0072344;modification-dependent protein catabolic process#GO:0019941;protein biosynthetic process#GO:0160307;catabolic process#GO:0009056;cytoplasmic translation#GO:0002181;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;translational elongation#GO:0006414;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000002380.4|UniProtKB=A0A5F8GPC2 A0A5F8GPC2 PAH PTHR11473:SF44 AROMATIC AMINO ACID HYDROXYLASE PHENYLALANINE-4-HYDROXYLASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;oxoacid metabolic process#GO:0043436;aromatic amino acid biosynthetic process#GO:0009073;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000011595.4|UniProtKB=F6UZM6 F6UZM6 NEMP2 PTHR13598:SF3 AT07567P-RELATED NUCLEAR ENVELOPE INTEGRAL MEMBRANE PROTEIN 2 nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000004831.2|UniProtKB=F6ULU0 F6ULU0 PTHR31526:SF4 SOSS COMPLEX SUBUNIT C SOSS COMPLEX SUBUNIT C DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000011424.3|UniProtKB=F6RKI0 F6RKI0 PTHR16675:SF67 MHC CLASS I-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000008768.5|UniProtKB=F6RGP4 F6RGP4 PHF2 PTHR23123:SF14 PHD/F-BOX CONTAINING PROTEIN LYSINE-SPECIFIC DEMETHYLASE PHF2 histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;protein demethylase activity#GO:0140457 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000025609.3|UniProtKB=F7FG79 F7FG79 LOC100026824 PTHR11955:SF83 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, ADIPOCYTE organic acid binding#GO:0043177;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;lipid binding#GO:0008289;fatty acid binding#GO:0005504 macromolecule localization#GO:0033036;lipid transport#GO:0006869;lipid localization#GO:0010876;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;localization#GO:0051179;fatty acid transport#GO:0015908;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000018429.5|UniProtKB=F6XC56 F6XC56 ZDHHC19 PTHR22883:SF326 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC19 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 cellular component organization#GO:0016043;protein targeting#GO:0006605;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;cellular process#GO:0009987;developmental maturation#GO:0021700;protein targeting to membrane#GO:0006612;developmental process#GO:0032502;synaptic vesicle maturation#GO:0016188;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000005246.4|UniProtKB=F6YMW4 F6YMW4 RSPO2 PTHR46987:SF4 NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN R-SPONDIN-2 binding#GO:0005488;signaling receptor binding#GO:0005102;receptor serine/threonine kinase binding#GO:0033612;protein binding#GO:0005515 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000045210.1|UniProtKB=A0A5F8G9J5 A0A5F8G9J5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009061.5|UniProtKB=F7FR24 F7FR24 SGPP1 PTHR14969:SF45 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE SPHINGOSINE-1-PHOSPHATE PHOSPHATASE 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;lipid modification#GO:0030258;dephosphorylation#GO:0016311;lipid metabolic process#GO:0006629;alcohol metabolic process#GO:0006066;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 phosphatase#PC00181;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000027446.2|UniProtKB=K7DZB1 K7DZB1 LOC103106895 PTHR33861:SF4 PROTEIN CBG18333 MEIOSIS-SPECIFIC COILED-COIL DOMAIN-CONTAINING PROTEIN MEIOC regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;male gamete generation#GO:0048232;biological regulation#GO:0065007;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;meiotic nuclear division#GO:0140013;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;cell cycle#GO:0007049;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;regulation of RNA stability#GO:0043487;sexual reproduction#GO:0019953;positive regulation of biosynthetic process#GO:0009891;organelle fission#GO:0048285;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;multicellular organismal reproductive process#GO:0048609;organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;male meiotic nuclear division#GO:0007140;meiotic cell cycle#GO:0051321;negative regulation of RNA metabolic process#GO:0051253;cellular component organization or biogenesis#GO:0071840;regulation of mRNA metabolic process#GO:1903311;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;nuclear division#GO:0000280;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000020364.4|UniProtKB=F6XYP6 F6XYP6 CPSF7 PTHR23204:SF2 CLEAVAGE AND POLYADENYLATION SPECIFIC FACTOR CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 7 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000017923.4|UniProtKB=A0A5F8GGY3 A0A5F8GGY3 TMEM87A PTHR21229:SF19 LUNG SEVEN TRANSMEMBRANE RECEPTOR GOLGI-PH REGULATING CATION CHANNEL cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;Golgi stack#GO:0005795 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006347.4|UniProtKB=F6ZS59 F6ZS59 KANK2 PTHR24168:SF0 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 2 negative regulation of cell population proliferation#GO:0008285;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;negative regulation of organelle organization#GO:0010639;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of cell cycle G1/S phase transition#GO:1902806;negative regulation of protein polymerization#GO:0032272;regulation of cell population proliferation#GO:0042127;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of protein-containing complex assembly#GO:0031333;cellular process#GO:0009987;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of signal transduction#GO:0009968;regulation of anatomical structure size#GO:0090066;negative regulation of RNA metabolic process#GO:0051253;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of cell cycle#GO:0051726;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of actin filament length#GO:0030832;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mitotic cell cycle#GO:0007346;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;regulation of signal transduction#GO:0009966;regulation of actin polymerization or depolymerization#GO:0008064;regulation of RNA biosynthetic process#GO:2001141;regulation of actin filament-based process#GO:0032970;negative regulation of cell cycle process#GO:0010948;regulation of gene expression#GO:0010468;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of DNA-templated transcription#GO:0006355;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of actin cytoskeleton organization#GO:0032956;regulation of cell cycle process#GO:0010564;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cell cycle#GO:0045786;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component size#GO:0032535;negative regulation of metabolic process#GO:0009892;regulation of intracellular signal transduction#GO:1902531;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of DNA-templated transcription#GO:0045892;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000042260.1|UniProtKB=A0A5F8GKP0 A0A5F8GKP0 PTHR34141:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000008179.2|UniProtKB=F7E4X2 F7E4X2 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000005586.4|UniProtKB=F7E4J4 F7E4J4 ESRRB PTHR48092:SF7 KNIRPS-RELATED PROTEIN-RELATED STEROID HORMONE RECEPTOR ERR2 signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000040165.1|UniProtKB=A0A5F8HHH1 A0A5F8HHH1 PTHR26452:SF196 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AN6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000011721.4|UniProtKB=F7FSX5 F7FSX5 PTGS2 PTHR11903:SF8 PROSTAGLANDIN G/H SYNTHASE PROSTAGLANDIN G_H SYNTHASE 2 dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;icosanoid biosynthetic process#GO:0046456;unsaturated fatty acid biosynthetic process#GO:0006636;lipid biosynthetic process#GO:0008610;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;monocarboxylic acid biosynthetic process#GO:0072330;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;arachidonate metabolic process#GO:0019369;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;prostaglandin metabolic process#GO:0006693;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254 neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 oxygenase#PC00177;oxidoreductase#PC00176 CCKR signaling map#P06959>COX2#G06998;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cyclooxygenase#P00845;Toll receptor signaling pathway#P00054>Gene trancription#G01550;CCKR signaling map#P06959>COX2#G07292;Endothelin signaling pathway#P00019>COX-2#P00582;CCKR signaling map#P06959>COX2#P07080 MONDO|Ensembl=ENSMODG00000015951.3|UniProtKB=F7FRT9 F7FRT9 PTHR18860:SF7 14-3-3 PROTEIN 14-3-3 PROTEIN ZETA_DELTA scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;PI3 kinase pathway#P00048>14-3-3#P01206;EGF receptor signaling pathway#P00018>14-3-3#P00539;FGF signaling pathway#P00021>14-3-3#P00624 MONDO|Ensembl=ENSMODG00000011307.3|UniProtKB=F6WJF0 F6WJF0 ID4 PTHR11723:SF6 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-4 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;nervous system development#GO:0007399;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000014039.4|UniProtKB=F7FWN2 F7FWN2 LOC100010349 PTHR10766:SF176 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;localization within membrane#GO:0051668;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000011925.3|UniProtKB=F7DZC2 F7DZC2 MATR3 PTHR15592:SF2 MATRIN 3/NUCLEAR PROTEIN 220-RELATED MATRIN-3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000010760.4|UniProtKB=F7FK82 F7FK82 PTHR45655:SF17 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 guanylate cyclase activity#GO:0004383;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 response to oxygen levels#GO:0070482;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896 catalytic complex#GO:1902494;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 guanylate cyclase#PC00114;cyclase#PC00079 Endothelin signaling pathway#P00019>Guanylate cyclase#P00581;Gonadotropin-releasing hormone receptor pathway#P06664>GC#P06726 MONDO|Ensembl=ENSMODG00000014388.3|UniProtKB=F6T7B2 F6T7B2 SDHD PTHR13337:SF2 SUCCINATE DEHYDROGENASE SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL heme binding#GO:0020037;binding#GO:0005488;small molecule binding#GO:0036094;tetrapyrrole binding#GO:0046906 respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;catalytic complex#GO:1902494;respiratory chain complex II (succinate dehydrogenase)#GO:0045273 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000042909.1|UniProtKB=A0A5F8GAX9 A0A5F8GAX9 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000024707.2|UniProtKB=F7AET4 F7AET4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000029780.2|UniProtKB=K7E044 K7E044 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000037375.1|UniProtKB=A0A5F8HGB7 A0A5F8HGB7 DYRK1B PTHR24058:SF12 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1B kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;catalytic activity, acting on a protein#GO:0140096;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000009510.4|UniProtKB=F7F9H9 F7F9H9 OPRK1 PTHR24229:SF1 NEUROPEPTIDES RECEPTOR KAPPA-TYPE OPIOID RECEPTOR signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;binding#GO:0005488;molecular transducer activity#GO:0060089 sensory perception of pain#GO:0019233;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;system process#GO:0003008 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 Opioid prodynorphin pathway#P05916>Kappa Receptor#P05998;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 MONDO|Ensembl=ENSMODG00000047843.1|UniProtKB=A0A5F8GBB6 A0A5F8GBB6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000019736.4|UniProtKB=F6X3W5 F6X3W5 OTP PTHR46770:SF1 HOMEOBOX PROTEIN ORTHOPEDIA HOMEOBOX PROTEIN ORTHOPEDIA DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 system development#GO:0048731;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;cellular process#GO:0009987 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000021106.4|UniProtKB=F6UHX3 F6UHX3 PTHR45622:SF75 UBIQUITIN-PROTEIN LIGASE E3A-RELATED X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 localization#GO:0051179;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;sensory perception#GO:0007600;intraciliary transport#GO:0042073;visual perception#GO:0007601;catabolic process#GO:0009056;microtubule-based movement#GO:0007018;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;sensory perception of light stimulus#GO:0050953;primary metabolic process#GO:0044238;system process#GO:0003008;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;post-translational protein modification#GO:0043687;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;cilium organization#GO:0044782;cellular localization#GO:0051641;protein catabolic process#GO:0030163;microtubule-based transport#GO:0099111;modification-dependent macromolecule catabolic process#GO:0043632;nervous system process#GO:0050877;protein modification by small protein conjugation or removal#GO:0070647;cell projection organization#GO:0030030;protein modification by small protein conjugation#GO:0032446;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996 endomembrane system#GO:0012505;cytoplasm#GO:0005737;9+0 non-motile cilium#GO:0097731;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;Golgi apparatus#GO:0005794;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;intracellular organelle#GO:0043229;cilium#GO:0005929 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000018116.3|UniProtKB=F7F1Z8 F7F1Z8 COQ3 PTHR43464:SF104 METHYLTRANSFERASE UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;transferase activity#GO:0016740;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;ketone metabolic process#GO:0042180;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 methyltransferase#PC00155;transferase#PC00220 MONDO|Ensembl=ENSMODG00000037999.1|UniProtKB=A0A5F8GRV3 A0A5F8GRV3 RPS19BP1 PTHR31454:SF2 ACTIVE REGULATOR OF SIRT1 ACTIVE REGULATOR OF SIRT1 binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000004303.4|UniProtKB=F6SX00 F6SX00 ANKRD13A PTHR12447:SF4 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of cellular process#GO:0050794;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of endocytosis#GO:0030100 late endosome#GO:0005770;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013168.3|UniProtKB=F6ZM60 F6ZM60 KCNK5 PTHR11003:SF241 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 5 channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215 transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000018094.5|UniProtKB=F7FFR7 F7FFR7 CHD4 PTHR45623:SF22 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD4 binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;DNA binding#GO:0003677;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;pyrophosphatase activity#GO:0016462;histone binding#GO:0042393;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000018270.4|UniProtKB=F6Q754 F6Q754 LYRM2 PTHR13675:SF0 LYR MOTIF-CONTAINING PROTEIN 2 LYR MOTIF-CONTAINING PROTEIN 2 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000038330.1|UniProtKB=A0A5F8HJM7 A0A5F8HJM7 NT5C1A PTHR31367:SF2 CYTOSOLIC 5'-NUCLEOTIDASE 1 FAMILY MEMBER CYTOSOLIC 5'-NUCLEOTIDASE 1A nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;adenosine metabolic process#GO:0046085;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine nucleoside metabolic process#GO:0042278 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000013285.4|UniProtKB=F7A9Z9 F7A9Z9 DPAGT1 PTHR10571:SF0 UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;membrane#GO:0016020 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000004660.5|UniProtKB=A0A5F8H807 A0A5F8H807 GIGYF1 PTHR14445:SF37 GRB10 INTERACTING GYF PROTEIN GRB10-INTERACTING GYF PROTEIN 1 translation regulator activity#GO:0045182 negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;insulin-like growth factor receptor signaling pathway#GO:0048009;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000016836.4|UniProtKB=F6R231 F6R231 UST PTHR12129:SF15 HEPARAN SULFATE 2-O-SULFOTRANSFERASE URONYL 2-SULFOTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000043479.1|UniProtKB=A0A5F8H815 A0A5F8H815 monDomV1R1232 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016022.4|UniProtKB=F7EFW8 F7EFW8 LMAN2L PTHR12223:SF20 VESICULAR MANNOSE-BINDING LECTIN VIP36-LIKE PROTEIN binding#GO:0005488;small molecule binding#GO:0036094;monosaccharide binding#GO:0048029;carbohydrate binding#GO:0030246 Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000001805.4|UniProtKB=A0A5F8H183 A0A5F8H183 TMC6 PTHR23302:SF4 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 6 gated channel activity#GO:0022836;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000025565.3|UniProtKB=A0A5F8HG26 A0A5F8HG26 PTHR10078:SF35 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-18 cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;response to other organism#GO:0051707;immune response#GO:0006955;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;response to bacterium#GO:0009617;inflammatory response#GO:0006954;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to molecule of bacterial origin#GO:0002237;response to peptide#GO:1901652;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to oxygen-containing compound#GO:1901700 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 interleukin superfamily#PC00128;cytokine#PC00083;intercellular signal molecule#PC00207 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870;Toll receptor signaling pathway#P00054>Gene trancription#G01550;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>INFgamma#P00878;Interleukin signaling pathway#P00036>Interleukin#P00970 MONDO|Ensembl=ENSMODG00000008970.4|UniProtKB=F7G2B9 F7G2B9 PTHR42687:SF1 L-THREONINE 3-DEHYDROGENASE L-THREONINE 3-DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000017216.4|UniProtKB=F6WYI0 F6WYI0 PTHR15712:SF23 ARMADILLO REPEAT CONTAINING PROTEIN ARMADILLO REPEAT CONTAINING 10 establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;cellular localization#GO:0051641;localization#GO:0051179;organelle localization#GO:0051640;axonal transport#GO:0098930;microtubule-based transport#GO:0099111;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;axo-dendritic transport#GO:0008088;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;mitochondrion localization#GO:0051646;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017612.3|UniProtKB=A0A5F8GP65 A0A5F8GP65 TUBA1B PTHR11588:SF251 TUBULIN TUBULIN ALPHA-1B CHAIN ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076 cell cycle#GO:0007049;cellular component organization#GO:0016043;cell differentiation#GO:0030154;mitotic cell cycle#GO:0000278;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;system development#GO:0048731;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;microtubule-based process#GO:0007017;neurogenesis#GO:0022008 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;tubulin#PC00228 Gonadotropin-releasing hormone receptor pathway#P06664>Tubulin#P06772 MONDO|Ensembl=ENSMODG00000039523.1|UniProtKB=A0A5F8H403 A0A5F8H403 SMAD7 PTHR13703:SF44 SMAD SMAD FAMILY MEMBER 7 molecular function regulator activity#GO:0098772;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of macromolecule metabolic process#GO:0060255;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 TGF-beta signaling pathway#P00052>I-Smads#P01289;TGF-beta signaling pathway#P00052>I-SMAD#G01548 MONDO|Ensembl=ENSMODG00000020062.2|UniProtKB=F6YSJ0 F6YSJ0 LOC100024559 PTHR48018:SF21 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AP2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009571.3|UniProtKB=F7AX56 F7AX56 PEX19 PTHR12774:SF2 PEROXISOMAL BIOGENESIS FACTOR 19 PEROXISOMAL BIOGENESIS FACTOR 19 signal sequence receptor activity#GO:0005048 protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;peroxisomal transport#GO:0043574;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000005744.4|UniProtKB=F6QE97 F6QE97 TMEM186 PTHR13603:SF1 TRANSMEMBRANE PROTEIN 186 TRANSMEMBRANE PROTEIN 186 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000014146.5|UniProtKB=F6XJZ1 F6XJZ1 DAXX PTHR12766:SF13 DEATH DOMAIN-ASSOCIATED PROTEIN 6 DAXX DEATH DOMAIN-ASSOCIATED PROTEIN 6 transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;transcription coregulator activity#GO:0003712;DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription regulator activity#GO:0140110;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;apoptotic signaling pathway#GO:0097190;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Apoptosis signaling pathway#P00006>DAXX#P00296;FAS signaling pathway#P00020>DAXX#P00602 MONDO|Ensembl=ENSMODG00000008174.3|UniProtKB=F7E5B6 F7E5B6 DUSP9 PTHR10159:SF388 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 9 protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of response to stimulus#GO:0048585;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;negative regulation of intracellular signal transduction#GO:1902532 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000044976.1|UniProtKB=A0A5F8H356 A0A5F8H356 PTHR35665:SF1 PROTEIN LKAAEAR1 PROTEIN LKAAEAR1 MONDO|Ensembl=ENSMODG00000010731.4|UniProtKB=A0A5F8H232 A0A5F8H232 PTHR11412:SF81 MACROGLOBULIN / COMPLEMENT COMPLEMENT C3 cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;humoral immune response#GO:0006959;positive regulation of immune response#GO:0050778;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;immune response#GO:0006955;defense response to symbiont#GO:0140546;complement activation#GO:0006956;activation of immune response#GO:0002253;positive regulation of response to stimulus#GO:0048584;defense response to other organism#GO:0098542;biological regulation#GO:0065007;response to other organism#GO:0051707 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;extracellular region#GO:0005576 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000004809.5|UniProtKB=A0A5F8G906 A0A5F8G906 PTHR10498:SF10 PARALEMMIN-RELATED PALM2-AKAP2 FUSION MONDO|Ensembl=ENSMODG00000001016.4|UniProtKB=F6ZFH1 F6ZFH1 PLIN5 PTHR14024:SF9 PERILIPIN PERILIPIN-5 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;lipid storage#GO:0019915;regulation of biological process#GO:0050789;regulation of localization#GO:0032879 intracellular organelle#GO:0043229;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cytosol#GO:0005829;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000047565.1|UniProtKB=A0A5F8G5V4 A0A5F8G5V4 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012255.4|UniProtKB=F6YGT3 F6YGT3 KCNT2 PTHR10027:SF9 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN POTASSIUM CHANNEL SUBFAMILY T MEMBER 2 transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion-gated channel activity#GO:0022839;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832 potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000001942.4|UniProtKB=F6VJU0 F6VJU0 GASK1B PTHR15905:SF1 GOLGI-ASSOCIATED KINASE 1B-RELATED GOLGI-ASSOCIATED KINASE 1B MONDO|Ensembl=ENSMODG00000019312.4|UniProtKB=F6YAU0 F6YAU0 DHRS13 PTHR43157:SF44 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 13 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000041133.1|UniProtKB=A0A5F8GB04 A0A5F8GB04 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000021193.4|UniProtKB=F6XVS7 F6XVS7 MOGAT1 PTHR12317:SF26 DIACYLGLYCEROL O-ACYLTRANSFERASE 2-ACYLGLYCEROL O-ACYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;neutral lipid metabolic process#GO:0006638 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000006691.3|UniProtKB=F7F290 F7F290 ELOF1 PTHR20934:SF0 TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG binding#GO:0005488;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175 gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023 MONDO|Ensembl=ENSMODG00000006010.3|UniProtKB=F6SKD2 F6SKD2 NCALD PTHR23055:SF87 CALCIUM BINDING PROTEINS NEUROCALCIN-DELTA protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000025153.1|UniProtKB=F7GHY6 F7GHY6 TASL PTHR14889:SF3 RCG36411 TLR ADAPTER INTERACTING WITH SLC15A4 ON THE LYSOSOME MONDO|Ensembl=ENSMODG00000008721.4|UniProtKB=A0A5F8HIB9 A0A5F8HIB9 NOP53 PTHR14211:SF7 GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2 RIBOSOME BIOGENESIS PROTEIN NOP53 RNA binding#GO:0003723;binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;ribosomal large subunit assembly#GO:0000027;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000010661.4|UniProtKB=H9H6E3 H9H6E3 VPS26A PTHR12233:SF4 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26A transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;cytosolic transport#GO:0016482 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;retromer complex#GO:0030904 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000017400.4|UniProtKB=F7E4R3 F7E4R3 S100A6 PTHR11639:SF80 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A6 calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000040853.1|UniProtKB=A0A5F8GUP3 A0A5F8GUP3 PTHR10962:SF4 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2B binding#GO:0005488;peptide binding#GO:0042277 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 MONDO|Ensembl=ENSMODG00000018176.4|UniProtKB=F6T9N9 F6T9N9 BACH2 PTHR46105:SF8 AGAP004733-PA TRANSCRIPTION REGULATOR PROTEIN BACH2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006381.3|UniProtKB=A0A5F8GIM7 A0A5F8GIM7 PTHR46172:SF1 DNA POLYMERASE EPSILON SUBUNIT 3 DNA POLYMERASE EPSILON SUBUNIT 3 chromatin binding#GO:0003682;chromatin DNA binding#GO:0031490;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ISWI-type complex#GO:0031010;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;epsilon DNA polymerase complex#GO:0008622;membraneless organelle#GO:0043228;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000008747.4|UniProtKB=F6PSM3 F6PSM3 KRT4 PTHR45616:SF3 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 4 structural molecule activity#GO:0005198 cellular component organization#GO:0016043;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular process#GO:0009987;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epidermis development#GO:0008544;developmental process#GO:0032502;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080 MONDO|Ensembl=ENSMODG00000036390.1|UniProtKB=A0A5F8G1W8 A0A5F8G1W8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000003479.3|UniProtKB=F7DBN7 F7DBN7 ZNF276 PTHR24406:SF3 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED ZINC FINGER PROTEIN 276 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000021094.3|UniProtKB=F6UIF8 F6UIF8 PTHR12682:SF11 ARCHEASE TRNA-SPLICING LIGASE-ACTIVATING FACTOR ARCHEASE catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 MONDO|Ensembl=ENSMODG00000011359.4|UniProtKB=F6SPW3 F6SPW3 COL5A2 PTHR24023:SF539 COLLAGEN ALPHA COLLAGEN TYPE V ALPHA 2 CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;supramolecular complex#GO:0099080;interstitial matrix#GO:0005614;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000011047.4|UniProtKB=A0A5F8GKC5 A0A5F8GKC5 PTHR14555:SF6 MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED RAB EFFECTOR MYRIP myosin binding#GO:0017022;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell cortex#GO:0005938;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;cellular anatomical structure#GO:0110165 myelin protein#PC00161 MONDO|Ensembl=ENSMODG00000038279.1|UniProtKB=A0A5F8GM59 A0A5F8GM59 STARD4 PTHR47006:SF1 STAR-RELATED LIPID TRANSFER PROTEIN 4 STAR-RELATED LIPID TRANSFER PROTEIN 4 cholesterol binding#GO:0015485;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;sterol binding#GO:0032934;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;small molecule binding#GO:0036094;binding#GO:0005488;steroid binding#GO:0005496;alcohol binding#GO:0043178;cholesterol transfer activity#GO:0120020;transporter activity#GO:0005215;sterol transfer activity#GO:0120015 intracellular sterol transport#GO:0032366;lipid transport#GO:0006869;cellular process#GO:0009987;lipid storage#GO:0019915;establishment of localization in cell#GO:0051649;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;sterol transport#GO:0015918;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907;lipid localization#GO:0010876 cytosol#GO:0005829;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000038287.1|UniProtKB=A0A5F8H6Q0 A0A5F8H6Q0 INSL5 PTHR20968:SF2 ILGF DOMAIN-CONTAINING PROTEIN INSULIN-LIKE PEPTIDE INSL5 signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of multicellular organismal process#GO:0051239;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 MONDO|Ensembl=ENSMODG00000027536.2|UniProtKB=K7E6B0 K7E6B0 IL9 PTHR16926:SF1 INTERLEUKIN 9 INTERLEUKIN-9 growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function activator activity#GO:0140677 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 interleukin superfamily#PC00128;cytokine#PC00083;intercellular signal molecule#PC00207 Interleukin signaling pathway#P00036>Interleukin#P00970 MONDO|Ensembl=ENSMODG00000045292.1|UniProtKB=A0A5F8GLJ6 A0A5F8GLJ6 PTHR10225:SF6 HYALURONAN RECEPTOR CD44 ANTIGEN molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;organic acid binding#GO:0043177;ion binding#GO:0043167;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 positive regulation of MAPK cascade#GO:0043410;defense response#GO:0006952;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;inflammatory response#GO:0006954;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>CD44#P00145;Alzheimer disease-presenilin pathway#P00004>CD44 intracellular fragment#P00121;Alzheimer disease-presenilin pathway#P00004>CD44 C-terminal fragment#P00123;Alzheimer disease-presenilin pathway#P00004>CD44 N-terminal fragment#P00174;Alzheimer disease-presenilin pathway#P00004>CD44 transmembrane fragment#P00167 MONDO|Ensembl=ENSMODG00000000035.3|UniProtKB=F6S0G1 F6S0G1 DDIT4 PTHR12478:SF7 DNA-DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN DDIT4 DNA DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN binding#GO:0005488;protein binding#GO:0005515 negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cell death#GO:0008219;apoptotic process#GO:0006915;response to oxygen levels#GO:0070482;negative regulation of biological process#GO:0048519;response to decreased oxygen levels#GO:0036293;programmed cell death#GO:0012501;response to abiotic stimulus#GO:0009628;response to hypoxia#GO:0001666;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;response to stress#GO:0006950 MONDO|Ensembl=ENSMODG00000017996.4|UniProtKB=F7B7V2 F7B7V2 AFG1L PTHR12169:SF6 ATPASE N2B AFG1-LIKE ATPASE ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000018708.4|UniProtKB=F7AVJ3 F7AVJ3 PTHR14199:SF38 NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 6-LIKE PROTEIN NBPF FAMILY MEMBER NBPF6-LIKE PROTEIN MONDO|Ensembl=ENSMODG00000023724.2|UniProtKB=A0A5F8G7L3 A0A5F8G7L3 PTHR11639:SF160 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A1 cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 sarcoplasmic reticulum#GO:0016529;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;sarcoplasm#GO:0016528;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000021462.4|UniProtKB=A0A5F8GKS9 A0A5F8GKS9 TGIF1 PTHR11850:SF59 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN TGIF1 double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000023727.3|UniProtKB=F6TXU5 F6TXU5 ACTMAP PTHR28631:SF1 UPF0692 PROTEIN C19ORF54 ACTIN MATURATION PROTEASE aminopeptidase activity#GO:0004177;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 MONDO|Ensembl=ENSMODG00000037627.1|UniProtKB=A0A5F8GEN7 A0A5F8GEN7 PTHR38653:SF1 GENE 572-RELATED CILIATED LEFT-RIGHT ORGANIZER ZP-N DOMAINS-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000016969.4|UniProtKB=F6V4Q8 F6V4Q8 FBXO41 PTHR15739:SF4 ZINC FINGER PROTEIN F-BOX ONLY PROTEIN 41 MONDO|Ensembl=ENSMODG00000020228.4|UniProtKB=A0A5F8G4C0 A0A5F8G4C0 CCNH PTHR10026:SF8 CYCLIN CYCLIN-H enzyme regulator activity#GO:0030234;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIIH holo complex#GO:0005675;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transferase complex#GO:1990234 kinase modulator#PC00140;kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000036796.1|UniProtKB=A0A5F8GX89 A0A5F8GX89 PTHR40389:SF3 ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED IGE-BINDING PROTEIN MONDO|Ensembl=ENSMODG00000007448.4|UniProtKB=A0A5F8G4J9 A0A5F8G4J9 C2CD3 PTHR21254:SF1 C2 DOMAIN-CONTAINING PROTEIN 3 C2 DOMAIN-CONTAINING PROTEIN 3 cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;protein localization to microtubule cytoskeleton#GO:0072698;plasma membrane bounded cell projection assembly#GO:0120031;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840;protein localization to centrosome#GO:0071539;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;centriole replication#GO:0007099;organelle assembly#GO:0070925;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;protein localization to microtubule organizing center#GO:1905508;localization#GO:0051179 intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriolar satellite#GO:0034451;centriole#GO:0005814;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000047873.1|UniProtKB=K7DZ31 K7DZ31 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000022529.3|UniProtKB=H9H833 H9H833 PTHR45869:SF21 C-REACTIVE PROTEIN-RELATED C-REACTIVE PROTEIN binding#GO:0005488;complement binding#GO:0001848;lipoprotein particle binding#GO:0071813;protein-lipid complex binding#GO:0071814;low-density lipoprotein particle binding#GO:0030169;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;immune system process#GO:0002376;inflammatory response#GO:0006954;innate immune response#GO:0045087;response to external stimulus#GO:0009605;acute inflammatory response#GO:0002526;defense response#GO:0006952 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000004154.3|UniProtKB=F6RA25 F6RA25 EIF3H PTHR10410:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT H translation factor activity#GO:0180051;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;translation initiation factor activity#GO:0003743;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787 translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;eukaryotic translation initiation factor 3 complex#GO:0005852;ribonucleoprotein complex#GO:1990904 translation factor#PC00223;translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000025189.1|UniProtKB=F7C1D0 F7C1D0 CCDC54 PTHR37880:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 54 COILED-COIL DOMAIN-CONTAINING PROTEIN 54 MONDO|Ensembl=ENSMODG00000019495.4|UniProtKB=F6W9X9 F6W9X9 LOC100012273 PTHR19321:SF1 PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED PROTEIN REGULATOR OF CYTOKINESIS 1 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 chromosome segregation#GO:0007059;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;spindle elongation#GO:0051231;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;nuclear division#GO:0000280;organelle assembly#GO:0070925;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;microtubule cytoskeleton organization involved in mitosis#GO:1902850;membraneless organelle assembly#GO:0140694;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278 membraneless organelle#GO:0043228;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000007046.4|UniProtKB=A0A5F8HDC0 A0A5F8HDC0 SIPA1L1 PTHR15711:SF10 RAP GTPASE-ACTIVATING PROTEIN SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE PROTEIN 1 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 regulation of cell projection organization#GO:0031344;regulation of synaptic plasticity#GO:0048167;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;regulation of trans-synaptic signaling#GO:0099177;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;actin filament-based process#GO:0030029;regulation of signaling#GO:0023051;regulation of synapse organization#GO:0050807;regulation of dendritic spine morphogenesis#GO:0061001;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of developmental process#GO:0050793 GTPase-activating protein#PC00257;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000016223.4|UniProtKB=A0A5F8GZ57 A0A5F8GZ57 OSER1 PTHR31383:SF2 OXIDATIVE STRESS-RESPONSE SERINE-RICH PROTEIN 1 OXIDATIVE STRESS-RESPONSIVE SERINE-RICH PROTEIN 1 MONDO|Ensembl=ENSMODG00000019370.5|UniProtKB=F6WSS4 F6WSS4 FSD2 PTHR24099:SF6 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FIBRONECTIN TYPE III AND SPRY DOMAIN-CONTAINING PROTEIN 2 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000010710.3|UniProtKB=A4UMC6 A4UMC6 TFIP11 PTHR23329:SF1 TUFTELIN-INTERACTING PROTEIN 11-RELATED TUFTELIN-INTERACTING PROTEIN 11 RNA metabolic process#GO:0016070;cellular component disassembly#GO:0022411;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;protein-containing complex disassembly#GO:0032984;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000024304.2|UniProtKB=F7EI24 F7EI24 PTHR48018:SF75 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000708.4|UniProtKB=A0A5F8G2L3 A0A5F8G2L3 PTHR14958:SF24 POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD17 binding#GO:0005488;protein binding#GO:0005515 positive regulation of cell projection organization#GO:0031346;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;protein metabolic process#GO:0019538;regulation of cell projection assembly#GO:0060491;primary metabolic process#GO:0044238;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;regulation of plasma membrane bounded cell projection assembly#GO:0120032;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of cilium assembly#GO:1902017;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of organelle assembly#GO:1902115;positive regulation of cellular component biogenesis#GO:0044089;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000027800.2|UniProtKB=K7E416 K7E416 PTHR22589:SF51 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 2, MITOCHONDRIAL acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000022806.2|UniProtKB=H9H985 H9H985 PTHR22846:SF40 WD40 REPEAT PROTEIN F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN TBL1XR1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transcription repressor complex#GO:0017053;protein-containing complex#GO:0032991;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974 Wnt signaling pathway#P00057>Ebi#P01453 MONDO|Ensembl=ENSMODG00000001106.3|UniProtKB=F7DPG9 F7DPG9 KCNK12 PTHR11003:SF11 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 12 potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215 cellular process#GO:0009987;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000023104.1|UniProtKB=F7AZP2 F7AZP2 SOCS5 PTHR10155:SF15 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 5 cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 MONDO|Ensembl=ENSMODG00000046265.1|UniProtKB=A0A5F8GPQ0 A0A5F8GPQ0 PTHR10806:SF12 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11C catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;peptidase complex#GO:1905368;membrane#GO:0016020 serine protease#PC00203 Vasopressin synthesis#P04395>Signal Peptidase#P04589;Endothelin signaling pathway#P00019>signal peptidase#P00573 MONDO|Ensembl=ENSMODG00000012064.4|UniProtKB=A0A5F8H4N2 A0A5F8H4N2 ZNF326 PTHR12190:SF1 A-KINASE ANCHOR PROTEIN AKAP 8 DBIRD COMPLEX SUBUNIT ZNF326 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription elongation#GO:0032784;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007922.4|UniProtKB=A0A5F8GI06 A0A5F8GI06 BSCL2 PTHR21212:SF0 BERNARDINELLI-SEIP CONGENITAL LIPODYSTROPHY 2 HOMOLOG BSCL2 PROTEIN SEIPIN lipid storage#GO:0019915;cellular process#GO:0009987;organelle organization#GO:0006996;lipid droplet organization#GO:0034389;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000048297.1|UniProtKB=K7E167 K7E167 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000005750.4|UniProtKB=F6QDB6 F6QDB6 PLCE1 PTHR10336:SF6 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE EPSILON-1 glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;hydrolase activity#GO:0016787 metabolic process#GO:0008152;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;signal transduction#GO:0007165;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;glycerophospholipid metabolic process#GO:0006650;monoatomic cation transmembrane transport#GO:0098655;intracellular signaling cassette#GO:0141124;G protein-coupled receptor signaling pathway#GO:0007186;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;signaling#GO:0023052;transport#GO:0006810;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;establishment of localization#GO:0051234;organophosphate metabolic process#GO:0019637;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;Ras protein signal transduction#GO:0007265;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644;metal ion transport#GO:0030001 lipase#PC00143;phospholipase#PC00186;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 MONDO|Ensembl=ENSMODG00000023338.2|UniProtKB=F6Z8A0 F6Z8A0 TRAPPC3L PTHR13048:SF1 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3-LIKE PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization in cell#GO:0051649;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;vesicle tethering complex#GO:0099023;cis-Golgi network#GO:0005801;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794 MONDO|Ensembl=ENSMODG00000045069.1|UniProtKB=F7F233 F7F233 LOC100617652 PTHR24242:SF264 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 10X1 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000023279.2|UniProtKB=F6SEJ1 F6SEJ1 MRPL41 PTHR21338:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L41 LARGE RIBOSOMAL SUBUNIT PROTEIN ML41 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000001054.3|UniProtKB=F6YRI3 F6YRI3 PTHR45747:SF3 HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) HISTONE-LYSINE N-METHYLTRANSFERASE EZH2 lysine N-methyltransferase activity#GO:0016278;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;chromatin binding#GO:0003682;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;binding#GO:0005488;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;PcG protein complex#GO:0031519;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000006364.5|UniProtKB=F6ZQU4 F6ZQU4 TMEM86A PTHR31885:SF9 GH04784P LYSOPLASMALOGENASE TMEM86A catalytic activity#GO:0003824;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000025236.1|UniProtKB=F7F6A1 F7F6A1 LOC100024563 PTHR26454:SF72 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C74 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007716.4|UniProtKB=F7EUW8 F7EUW8 RIPK2 PTHR44329:SF9 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED RECEPTOR-INTERACTING SERINE_THREONINE-PROTEIN KINASE 2 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;MAP kinase kinase kinase activity#GO:0004709 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;defense response to other organism#GO:0098542;cellular process#GO:0009987;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cell communication#GO:0007154;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;immune response#GO:0006955 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000027883.2|UniProtKB=H9H7G1 H9H7G1 PTHR24103:SF676 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000018978.5|UniProtKB=F7FPA7 F7FPA7 PTHR11909:SF297 CASEIN KINASE-RELATED TAU-TUBULIN KINASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000041509.1|UniProtKB=A0A5F8GPM2 A0A5F8GPM2 monDomV1R1231 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020376.4|UniProtKB=F7F6E0 F7F6E0 PRLR PTHR23036:SF86 CYTOKINE RECEPTOR PROLACTIN RECEPTOR immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 positive regulation of cell population proliferation#GO:0008284;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;response to peptide#GO:1901652;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>PRLR#P06822 MONDO|Ensembl=ENSMODG00000013835.4|UniProtKB=F6SDK7 F6SDK7 PTHR46118:SF4 PROTEIN ABHD11 SN-1-SPECIFIC DIACYLGLYCEROL LIPASE ABHD11 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000005554.3|UniProtKB=F7FH35 F7FH35 PSMB6 PTHR11599:SF46 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-6 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000028867.2|UniProtKB=K7E431 K7E431 PTHR10751:SF117 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 6 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 G-protein#PC00020;heterotrimeric G-protein#PC00117 MONDO|Ensembl=ENSMODG00000016132.4|UniProtKB=F7DS89 F7DS89 IPMK PTHR12400:SF51 INOSITOL POLYPHOSPHATE KINASE INOSITOL POLYPHOSPHATE MULTIKINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 kinase#PC00137 MONDO|Ensembl=ENSMODG00000019154.5|UniProtKB=F7BK37 F7BK37 ANKRD17 PTHR23206:SF1 MASK PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 17 response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000013216.4|UniProtKB=F7EVW3 F7EVW3 XPNPEP2 PTHR43763:SF4 XAA-PRO AMINOPEPTIDASE 1 XAA-PRO AMINOPEPTIDASE 2 protease#PC00190 MONDO|Ensembl=ENSMODG00000009405.4|UniProtKB=A0A5F8H8S0 A0A5F8H8S0 PTHR12080:SF18 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE SLAM FAMILY MEMBER 9 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;immune response#GO:0006955;cellular process#GO:0009987;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;immune system process#GO:0002376;cell activation#GO:0001775;cell communication#GO:0007154;leukocyte activation#GO:0045321;T cell activation#GO:0042110;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000010269.3|UniProtKB=F6VPE2 F6VPE2 LOC100617130 PTHR26451:SF68 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 6K2 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000015399.4|UniProtKB=F6T507 F6T507 SLC1A1 PTHR11958:SF109 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 3 metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;monoatomic cation transmembrane transporter activity#GO:0008324;sodium:dicarboxylate symporter activity#GO:0017153;symporter activity#GO:0015293;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943 nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987;dicarboxylic acid transport#GO:0006835;L-glutamate transmembrane transport#GO:0015813;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;transport#GO:0006810;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;L-glutamate import#GO:0051938;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036;Ionotropic glutamate receptor pathway#P00037>EAAT#P01011 MONDO|Ensembl=ENSMODG00000028801.2|UniProtKB=K7E2F0 K7E2F0 PTHR10127:SF814 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING MEPRIN A SUBUNIT BETA catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000027635.2|UniProtKB=K7E5H2 K7E5H2 LOC100014747 PTHR22883:SF22 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC11-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;protein targeting#GO:0006605;antiviral innate immune response#GO:0140374;defense response to virus#GO:0051607;localization#GO:0051179;response to virus#GO:0009615;cellular localization#GO:0051641;localization within membrane#GO:0051668;immune system process#GO:0002376;response to other organism#GO:0051707;defense response to other organism#GO:0098542;establishment of protein localization#GO:0045184;immune response#GO:0006955;defense response to symbiont#GO:0140546;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;establishment of localization#GO:0051234;innate immune response#GO:0045087;protein targeting to membrane#GO:0006612 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000001994.4|UniProtKB=F6RHU5 F6RHU5 TRIP11 PTHR18921:SF2 MYOSIN HEAVY CHAIN - RELATED THYROID RECEPTOR-INTERACTING PROTEIN 11 enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515;small GTPase binding#GO:0031267 vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component organization#GO:0016043;establishment of localization in cell#GO:0051649;Golgi organization#GO:0007030;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular localization#GO:0051641;establishment of localization#GO:0051234;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 actin binding motor protein#PC00040;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000002576.3|UniProtKB=F7GF68 F7GF68 PTHR36870:SF1 C17ORF78 ISOFORM 2 SIMILAR TO HUMAN CHROMOSOME 17 OPEN READING FRAME 78 MONDO|Ensembl=ENSMODG00000041068.1|UniProtKB=A0A5F8GCQ5 A0A5F8GCQ5 PTHR11346:SF97 GALECTIN GALECTIN-1 protein binding#GO:0005515;carbohydrate binding#GO:0030246;extracellular matrix binding#GO:0050840;laminin binding#GO:0043236;oligosaccharide binding#GO:0070492;binding#GO:0005488 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000010795.5|UniProtKB=A0A5F8H793 A0A5F8H793 ASXL3 PTHR13578:SF18 ADDITIONAL SEX COMBS LIKE PROTEIN ASXL POLYCOMB GROUP PROTEIN ASXL3-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;chromatin binding#GO:0003682 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase II#GO:0045944;developmental process#GO:0032502;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;animal gross anatomical part developmental process#GO:0160108;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;PcG protein complex#GO:0031519;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000004422.4|UniProtKB=A0A5F8GXN0 A0A5F8GXN0 MYH6 PTHR45615:SF1 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-7 binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 striated muscle contraction#GO:0006941;actin-mediated cell contraction#GO:0070252;circulatory system development#GO:0072359;heart process#GO:0003015;muscle system process#GO:0003012;system development#GO:0048731;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;heart development#GO:0007507;blood circulation#GO:0008015;cellular process#GO:0009987;actin filament-based movement#GO:0030048;system process#GO:0003008;heart contraction#GO:0060047;animal organ development#GO:0048513;multicellular organism development#GO:0007275;muscle contraction#GO:0006936;developmental process#GO:0032502 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867 MONDO|Ensembl=ENSMODG00000006461.4|UniProtKB=K7E3J4 K7E3J4 SPOUT1 PTHR12150:SF14 CLASS IV SAM-BINDING METHYLTRANSFERASE-RELATED 28S RRNA (URIDINE-N(3))-METHYLTRANSFERASE nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;localization#GO:0051179;organelle localization#GO:0051640;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;negative regulation of metabolic process#GO:0009892;centrosome localization#GO:0051642;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519 mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694;spindle pole#GO:0000922;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000017075.4|UniProtKB=F6VKW8 F6VKW8 SEMA3C PTHR11036:SF25 SEMAPHORIN SEMAPHORIN-3C molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;mesenchymal cell differentiation#GO:0048762;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;neural crest cell differentiation#GO:0014033;taxis#GO:0042330;response to chemical#GO:0042221;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;neural crest cell migration#GO:0001755;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;stem cell development#GO:0048864;chemotaxis#GO:0006935;cell motility#GO:0048870;regulation of cellular process#GO:0050794;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;mesenchyme development#GO:0060485;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;cell migration#GO:0016477;neural crest cell development#GO:0014032;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;axon development#GO:0061564;axon guidance#GO:0007411;stem cell differentiation#GO:0048863;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000047293.1|UniProtKB=F6YZY4 F6YZY4 LOC100025428 PTHR26454:SF17 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C70 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020936.4|UniProtKB=A0A5F8GI92 A0A5F8GI92 LOC100026833 PTHR45616:SF52 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CUTICULAR HB3 structural molecule activity#GO:0005198 cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;skin development#GO:0043588;cytoskeleton organization#GO:0007010;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;multicellular organismal process#GO:0032501;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular developmental process#GO:0048869;developmental process#GO:0032502;epidermis development#GO:0008544 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000050687.1|UniProtKB=F6U9S7 F6U9S7 LOC130454392 PTHR26452:SF125 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13A1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000047288.1|UniProtKB=A0A5F8GIY6 A0A5F8GIY6 PTHR12884:SF18 60S RIBOSOMAL PROTEIN L29 60S RIBOSOMAL PROTEIN L29 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000025148.2|UniProtKB=F7CLB4 F7CLB4 LINGO2 PTHR24373:SF38 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT AND IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING NOGO RECEPTOR-INTERACTING PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004837.3|UniProtKB=F6UL26 F6UL26 LRIG3 PTHR24373:SF311 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS PROTEIN 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of sound#GO:0007605;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000041000.1|UniProtKB=A0A5F8GA86 A0A5F8GA86 TIGAR PTHR46517:SF1 FRUCTOSE-2,6-BISPHOSPHATASE TIGAR FRUCTOSE-2,6-BISPHOSPHATASE TIGAR phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;sugar-phosphatase activity#GO:0050308 regulation of carbohydrate metabolic process#GO:0006109;negative regulation of cellular process#GO:0048523;negative regulation of catabolic process#GO:0009895;regulation of catabolic process#GO:0009894;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of primary metabolic process#GO:0080090;negative regulation of biological process#GO:0048519;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 Cobalamin biosynthesis#P02735>Ribazole-5-phosphate phosphatase#P02881 MONDO|Ensembl=ENSMODG00000050557.1|UniProtKB=A0A5F8H9A5 A0A5F8H9A5 PCTP PTHR19308:SF59 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN PHOSPHATIDYLCHOLINE TRANSFER PROTEIN transporter activity#GO:0005215;phospholipid binding#GO:0005543;phosphatidylcholine binding#GO:0031210;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylcholine intramembrane carrier activity#GO:0008525;ion binding#GO:0043167;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;lipid binding#GO:0008289;cation binding#GO:0043169;intramembrane lipid carrier activity#GO:0140303 MONDO|Ensembl=ENSMODG00000008323.2|UniProtKB=F7FGB9 F7FGB9 TMEM127 PTHR28358:SF1 TRANSMEMBRANE PROTEIN 127 TRANSMEMBRANE PROTEIN 127 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of TOR signaling#GO:0032006 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000029766.2|UniProtKB=K7E2S1 K7E2S1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008972.4|UniProtKB=F7G214 F7G214 PTHR24100:SF149 BUTYROPHILIN BG ANTIGEN 1, MHCB REGION-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000009545.4|UniProtKB=F7C3Z7 F7C3Z7 PTHR24217:SF13 PUTATIVE-RELATED SYNAPTOPODIN protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;regulation of cytoskeleton organization#GO:0051493;myofibril assembly#GO:0030239;regulation of supramolecular fiber organization#GO:1902903;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;positive regulation of actin filament bundle assembly#GO:0032233;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;actomyosin structure organization#GO:0031032;regulation of Rho protein signal transduction#GO:0035023;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;regulation of actin filament bundle assembly#GO:0032231;positive regulation of organelle organization#GO:0010638;striated muscle cell development#GO:0055002;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of small GTPase mediated signal transduction#GO:0051056;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989 cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;glutamatergic synapse#GO:0098978;supramolecular polymer#GO:0099081;neuron to neuron synapse#GO:0098984;supramolecular complex#GO:0099080;postsynaptic specialization#GO:0099572;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cell junction#GO:0030054;I band#GO:0031674;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000010431.4|UniProtKB=F6YTL4 F6YTL4 OPLAH PTHR11365:SF2 5-OXOPROLINASE RELATED 5-OXOPROLINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812 catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273;cellular process#GO:0009987;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000020574.4|UniProtKB=F7A1Q4 F7A1Q4 TMEM33 PTHR12703:SF4 TRANSMEMBRANE PROTEIN 33 TRANSMEMBRANE PROTEIN 33 endoplasmic reticulum tubular network organization#GO:0071786;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;nuclear envelope organization#GO:0006998;endoplasmic reticulum membrane organization#GO:0090158 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000036476.1|UniProtKB=A0A5F8G6I0 A0A5F8G6I0 SOX11 PTHR10270:SF113 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-11 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;sensory organ development#GO:0007423;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;camera-type eye morphogenesis#GO:0048593;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;camera-type eye development#GO:0043010;positive regulation of RNA metabolic process#GO:0051254;visual system development#GO:0150063;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;head development#GO:0060322;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;sensory system development#GO:0048880;negative regulation of macromolecule biosynthetic process#GO:0010558;eye development#GO:0001654;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of metabolic process#GO:0009892;sensory organ morphogenesis#GO:0090596;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 MONDO|Ensembl=ENSMODG00000006311.4|UniProtKB=F7BQZ9 F7BQZ9 LDLR PTHR24270:SF21 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR low-density lipoprotein particle receptor activity#GO:0005041;cargo receptor activity#GO:0038024 intracellular transport#GO:0046907;transport#GO:0006810;chemical homeostasis#GO:0048878;import into cell#GO:0098657;sterol transport#GO:0015918;cholesterol homeostasis#GO:0042632;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lipid transport#GO:0006869;vesicle-mediated transport#GO:0016192;lipid localization#GO:0010876;localization#GO:0051179;cellular localization#GO:0051641;organic hydroxy compound transport#GO:0015850;lipid homeostasis#GO:0055088;endocytosis#GO:0006897;homeostatic process#GO:0042592;intracellular sterol transport#GO:0032366 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219;apolipoprotein#PC00052 MONDO|Ensembl=ENSMODG00000039275.1|UniProtKB=F6VP59 F6VP59 LOC100015032 PTHR19375:SF581 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein refolding#GO:0042026;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072;Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 MONDO|Ensembl=ENSMODG00000024124.2|UniProtKB=F6Y0U5 F6Y0U5 LOC100026827 PTHR12490:SF4 GSK3B-INTERACTING PROTEIN GSK3B-INTERACTING PROTEIN binding#GO:0005488;protein kinase A binding#GO:0051018;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000024647.3|UniProtKB=F6XBS2 F6XBS2 FOXB1 PTHR11829:SF209 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN B1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000011283.3|UniProtKB=F6WZN2 F6WZN2 C2CD4B PTHR46291:SF8 C2 DOMAIN-CONTAINING PROTEIN C2 CALCIUM DEPENDENT DOMAIN CONTAINING 4A MONDO|Ensembl=ENSMODG00000002788.3|UniProtKB=F6YG37 F6YG37 NEK2 PTHR43671:SF115 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK2 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 microtubule cytoskeleton organization#GO:0000226;mitotic cell cycle phase transition#GO:0044772;cell cycle phase transition#GO:0044770;G2/M transition of mitotic cell cycle#GO:0000086;mitotic cell cycle#GO:0000278;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;microtubule organizing center organization#GO:0031023;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cell cycle G2/M phase transition#GO:0044839 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000009962.4|UniProtKB=F6Y8F9 F6Y8F9 INTS10 PTHR16055:SF2 INTEGRATOR COMPLEX SUBUNIT 10 INTEGRATOR COMPLEX SUBUNIT 10 RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;integrator complex#GO:0032039;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000046012.1|UniProtKB=F7GEE4 F7GEE4 PTHR26450:SF23 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E5 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000051554.1|UniProtKB=A0A5F8GK53 A0A5F8GK53 PTHR12653:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5 energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;electron transport chain#GO:0022900;metabolic process#GO:0008152;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091 respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000015159.4|UniProtKB=F7CF79 F7CF79 GADL1 PTHR45677:SF1 GLUTAMATE DECARBOXYLASE-RELATED ACIDIC AMINO ACID DECARBOXYLASE GADL1 lyase activity#GO:0016829;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 MONDO|Ensembl=ENSMODG00000009246.4|UniProtKB=F7DWA1 F7DWA1 UBE2O PTHR46116:SF51 (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;transferase activity#GO:0016740;catalytic activity#GO:0003824 vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000025111.1|UniProtKB=F6RNB3 F6RNB3 TIFA PTHR31266:SF2 TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN A FAMILY MEMBER TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN A cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;positive regulation of signal transduction#GO:0009967;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;intracellular receptor signaling pathway#GO:0030522;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;activation of innate immune response#GO:0002218;response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stress#GO:0080134;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;positive regulation of signaling#GO:0023056;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;positive regulation of response to external stimulus#GO:0032103;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;immune response-activating signaling pathway#GO:0002757 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000017829.4|UniProtKB=F6Z8W3 F6Z8W3 LOC100011628 PTHR11388:SF89 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1B1 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;bile acid transmembrane transporter activity#GO:0015125 monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;bile acid and bile salt transport#GO:0015721;lipid localization#GO:0010876;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036 basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000013732.4|UniProtKB=A0A5F8H302 A0A5F8H302 HIP1 PTHR10407:SF14 HUNTINGTIN INTERACTING PROTEIN 1 HUNTINGTIN-INTERACTING PROTEIN 1 protein-membrane adaptor activity#GO:0043495;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;cytoskeletal adaptor activity#GO:0008093;molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;regulation of apoptotic process#GO:0042981;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;endocytosis#GO:0006897;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;transport#GO:0006810;regulation of response to stimulus#GO:0048583;establishment of localization#GO:0051234;actin filament organization#GO:0007015;positive regulation of signal transduction#GO:0009967;regulation of ERBB signaling pathway#GO:1901184;positive regulation of cell communication#GO:0010647;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;actin filament-based process#GO:0030029;localization#GO:0051179;supramolecular fiber organization#GO:0097435 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;vesicle#GO:0031982;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;intracellular vesicle#GO:0097708;cortical cytoskeleton#GO:0030863;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cytoskeleton#GO:0005856;clathrin-coated vesicle#GO:0030136;cell junction#GO:0030054;membraneless organelle#GO:0043228;presynapse#GO:0098793;cell periphery#GO:0071944;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 Huntington disease#P00029>Hip-1#P00765 MONDO|Ensembl=ENSMODG00000018463.4|UniProtKB=A0A5F8G2Z0 A0A5F8G2Z0 PTHR23167:SF51 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED [F-ACTIN]-MONOOXYGENASE MICAL3 binding#GO:0005488;actin binding#GO:0003779;protein binding#GO:0005515;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;cytoskeletal protein binding#GO:0008092;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 actin filament-based process#GO:0030029;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;actin filament depolymerization#GO:0030042;cellular component organization#GO:0016043;organelle organization#GO:0006996;protein depolymerization#GO:0051261;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000023050.3|UniProtKB=A0A5F8GUL3 A0A5F8GUL3 LOC100619469 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000037625.1|UniProtKB=A0A5F8H7R1 A0A5F8H7R1 PTHR11588:SF530 TUBULIN AT04270P structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 tubulin#PC00228;cytoskeletal protein#PC00085 MONDO|Gene=KRAS|UniProtKB=Q07983 Q07983 KRAS PTHR24070:SF392 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE KRAS GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;intracellular signal transduction#GO:0035556;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 Ras Pathway#P04393>Ras#P04547;EGF receptor signaling pathway#P00018>Ras#P00552;TGF-beta signaling pathway#P00052>Ras-GDP#P01291;PDGF signaling pathway#P00047>Ras#P01154;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;VEGF signaling pathway#P00056>Ras#P01411;Integrin signalling pathway#P00034>Ras#P00916;Angiogenesis#P00005>Ras#P00238;p53 pathway feedback loops 2#P04398>Ras#P04651;FGF signaling pathway#P00021>Ras#P00633 MONDO|Ensembl=ENSMODG00000010132.3|UniProtKB=F6WN41 F6WN41 OR10J3 PTHR26451:SF28 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10J3 binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000047779.1|UniProtKB=A0A5F8H7P4 A0A5F8H7P4 PTHR12538:SF0 40S RIBOSOMAL PROTEIN S26 40S RIBOSOMAL PROTEIN S26 nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;mRNA binding#GO:0003729;RNA binding#GO:0003723;structural molecule activity#GO:0005198 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000008216.4|UniProtKB=F6ZYG5 F6ZYG5 EEF1AKMT1 PTHR13200:SF0 EEF1A LYSINE METHYLTRANSFERASE 1 EEF1A LYSINE METHYLTRANSFERASE 1 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 MONDO|Ensembl=ENSMODG00000042479.1|UniProtKB=F7DXR0 F7DXR0 LOC100018942 PTHR23430:SF220 HISTONE H2A HISTONE H2A TYPE 3 structural molecule activity#GO:0005198 negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of cellular process#GO:0048523 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000009492.3|UniProtKB=F7F9Z4 F7F9Z4 PLEKHG7 PTHR13217:SF6 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 MONDO|Ensembl=ENSMODG00000002091.3|UniProtKB=F6YQ65 F6YQ65 TNFSF14 PTHR11471:SF34 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of apoptotic process#GO:0043065;positive regulation of canonical NF-kappaB signal transduction#GO:0043123 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000038336.1|UniProtKB=A0A5F8G3B4 A0A5F8G3B4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000025434.1|UniProtKB=F6VLP3 F6VLP3 ZBTB33 PTHR24399:SF24 ZINC FINGER AND BTB DOMAIN-CONTAINING TRANSCRIPTIONAL REGULATOR KAISO sequence-specific DNA binding#GO:0043565;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017491.3|UniProtKB=F7FEQ0 F7FEQ0 TXLNA PTHR16127:SF12 TAXILIN ALPHA-TAXILIN membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000046665.1|UniProtKB=A0A5F8G4U9 A0A5F8G4U9 HAS2 PTHR22913:SF7 HYALURONAN SYNTHASE HYALURONAN SYNTHASE 2 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;polysaccharide biosynthetic process#GO:0000271;extracellular structure organization#GO:0043062;aminoglycan metabolic process#GO:0006022;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;aminoglycan biosynthetic process#GO:0006023;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;extracellular matrix assembly#GO:0085029;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;cellular component biogenesis#GO:0044085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000014758.4|UniProtKB=F7GGZ0 F7GGZ0 KLF11 PTHR23235:SF65 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 11 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008339.2|UniProtKB=F7F2M5 F7F2M5 SLC29A2 PTHR10332:SF8 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505 nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nucleobase-containing compound transport#GO:0015931;nucleobase transport#GO:0015851;transport#GO:0006810;pyrimidine nucleobase transport#GO:0015855;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 transporter#PC00227 MONDO|Ensembl=ENSMODG00000003935.4|UniProtKB=F7GIQ1 F7GIQ1 NEB PTHR11039:SF37 NEBULIN NEBULIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779 actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;system development#GO:0048731;anatomical structure development#GO:0048856;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;developmental process#GO:0032502;actin filament organization#GO:0007015;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869;multicellular organismal process#GO:0032501;tissue development#GO:0009888;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;anatomical structure morphogenesis#GO:0009653;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell development#GO:0048468;actomyosin structure organization#GO:0031032;circulatory system development#GO:0072359;cell differentiation#GO:0030154;striated muscle tissue development#GO:0014706;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cardiac muscle cell differentiation#GO:0055007;cytoskeleton organization#GO:0007010;heart development#GO:0007507;cellular component assembly#GO:0022607 Z disc#GO:0030018;contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;I band#GO:0031674;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017 MONDO|Ensembl=ENSMODG00000005918.3|UniProtKB=F6XCI3 F6XCI3 ATP6V0D1 PTHR11028:SF3 VACUOLAR ATP SYNTHASE SUBUNIT AC39 V-TYPE PROTON ATPASE SUBUNIT D 1 proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;localization#GO:0051179 proton-transporting two-sector ATPase complex#GO:0016469;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;transporter complex#GO:1990351;lysosomal membrane#GO:0005765;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;endosome#GO:0005768;ATPase complex#GO:1904949;early endosome#GO:0005769;ATPase dependent transmembrane transport complex#GO:0098533;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;organelle#GO:0043226;cellular anatomical structure#GO:0110165;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;endomembrane system#GO:0012505;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000013329.4|UniProtKB=A0A5F8GSB3 A0A5F8GSB3 SLC12A2 PTHR11827:SF58 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 2 symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873 monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;monoatomic anion transport#GO:0006820;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;cell body#GO:0044297;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;neuronal cell body#GO:0043025;apical part of cell#GO:0045177 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000006950.4|UniProtKB=F6RFX8 F6RFX8 PTHR23085:SF6 GH28348P JUNCTOPHILIN-1 cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;sarcoplasm#GO:0016528;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cell periphery#GO:0071944;sarcoplasmic reticulum#GO:0016529;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000000353.3|UniProtKB=A0A5F8HC58 A0A5F8HC58 PTHR19969:SF23 SH2-SH3 ADAPTOR PROTEIN-RELATED CRK-LIKE PROTEIN receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;protein-macromolecule adaptor activity#GO:0030674 positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell motility#GO:0048870;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cell migration#GO:0016477;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Crk#P00207;Integrin signalling pathway#P00034>Crk#P00933 MONDO|Ensembl=ENSMODG00000002016.4|UniProtKB=F6QXL0 F6QXL0 IKBKE PTHR22969:SF10 IKB KINASE INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT EPSILON transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;positive regulation of response to biotic stimulus#GO:0002833;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;activation of innate immune response#GO:0002218;regulation of cytokine production#GO:0001817;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;positive regulation of biosynthetic process#GO:0009891;positive regulation of type I interferon production#GO:0032481;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of response to external stimulus#GO:0032103;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;immune system process#GO:0002376;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Toll receptor signaling pathway#P00054>IKKepsilon#P01372;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IKK#P00871 MONDO|Ensembl=ENSMODG00000043322.1|UniProtKB=A0A5F8GZC2 A0A5F8GZC2 DLX6 PTHR24327:SF26 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;embryo development ending in birth or egg hatching#GO:0009792;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;developmental process#GO:0032502;embryo development#GO:0009790;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000002675.4|UniProtKB=F7CYW8 F7CYW8 FBN1 PTHR24039:SF22 FIBRILLIN-RELATED FIBRILLIN-1 extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000020488.2|UniProtKB=A0A5F8H8J8 A0A5F8H8J8 PTHR13651:SF1 PROTEIN ABITRAM PROTEIN ABITRAM protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin monomer binding#GO:0003785 anatomical structure morphogenesis#GO:0009653;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;regulation of actin filament length#GO:0030832;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;neuron development#GO:0048666;dendrite development#GO:0016358;cellular process#GO:0009987;neuron projection development#GO:0031175;regulation of actin cytoskeleton organization#GO:0032956;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of anatomical structure size#GO:0090066;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of supramolecular fiber organization#GO:1902903;dendrite morphogenesis#GO:0048813;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of cell projection assembly#GO:0060491;anatomical structure development#GO:0048856;regulation of actin filament organization#GO:0110053;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of actin filament polymerization#GO:0030833;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of cell projection organization#GO:0031344;regulation of actin filament-based process#GO:0032970;regulation of filopodium assembly#GO:0051489;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular developmental process#GO:0048869 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;lamellipodium#GO:0030027;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;cell leading edge#GO:0031252;nucleus#GO:0005634;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;dendrite#GO:0030425;filopodium#GO:0030175;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858 MONDO|Ensembl=ENSMODG00000019059.4|UniProtKB=F7AXM6 F7AXM6 FGF20 PTHR11486:SF72 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 20 protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083 regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;nervous system development#GO:0007399;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of cell motility#GO:2000145;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000001449.4|UniProtKB=F6SF82 F6SF82 PTHR15511:SF2 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 13B TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 13B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015101.4|UniProtKB=F7F370 F7F370 INSR PTHR24416:SF535 TYROSINE-PROTEIN KINASE RECEPTOR INSULIN RECEPTOR transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199 chemical homeostasis#GO:0048878;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;glucose homeostasis#GO:0042593;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;positive regulation of signaling#GO:0023056;carbohydrate homeostasis#GO:0033500;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of response to stimulus#GO:0048583;cellular response to insulin stimulus#GO:0032869;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular response to nitrogen compound#GO:1901699;positive regulation of response to stimulus#GO:0048584;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to nitrogen compound#GO:1901698;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 protein kinase complex#GO:1902911;signaling receptor complex#GO:0043235;transferase complex#GO:1990234;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;catalytic complex#GO:1902494;axon#GO:0030424;transferase complex, transferring phosphorus-containing groups#GO:0061695;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796 transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>IR#P06802;PI3 kinase pathway#P00048>IR#P01187;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895 MONDO|Ensembl=ENSMODG00000004710.4|UniProtKB=F6QH16 F6QH16 GALNT11 PTHR11675:SF63 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000024325.2|UniProtKB=F7DGD7 F7DGD7 PTHR48018:SF73 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8I2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000042691.1|UniProtKB=F6UPJ0 F6UPJ0 LOC100019409 PTHR48002:SF159 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4A16 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000022904.2|UniProtKB=F7DZG0 F7DZG0 PTHR26450:SF104 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018631.4|UniProtKB=F7B2M1 F7B2M1 PTHR47544:SF2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000016348.5|UniProtKB=A0A5F8G839 A0A5F8G839 TNRC6A PTHR13020:SF28 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6A PROTEIN negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;miRNA-mediated post-transcriptional gene silencing#GO:0035195;negative regulation of metabolic process#GO:0009892;positive regulation of metabolic process#GO:0009893;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000021199.4|UniProtKB=F6XE34 F6XE34 WDFY1 PTHR46189:SF2 LD41958P WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 1 positive regulation of immune system process#GO:0002684;positive regulation of pattern recognition receptor signaling pathway#GO:0062208;positive regulation of innate immune response#GO:0045089;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of response to external stimulus#GO:0032101;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to external stimulus#GO:0032103;regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;positive regulation of signaling#GO:0023056 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000024713.2|UniProtKB=F6ZQD8 F6ZQD8 PTHR10807:SF39 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 10 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000024444.2|UniProtKB=F7CZ29 F7CZ29 PSMB11 PTHR11599:SF48 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-11 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 nucleus#GO:0005634;proteasome complex#GO:0000502;cytosol#GO:0005829;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000010448.4|UniProtKB=A0A5F8GEZ3 A0A5F8GEZ3 INPP5D PTHR46051:SF3 SH2 DOMAIN-CONTAINING PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 5-PHOSPHATASE 1 regulation of immune response#GO:0050776;regulation of hemopoiesis#GO:1903706;positive regulation of lymphocyte activation#GO:0051251;regulation of tissue remodeling#GO:0034103;negative regulation of multicellular organismal process#GO:0051241;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;positive regulation of developmental process#GO:0051094;regulation of bone remodeling#GO:0046850;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;positive regulation of cell activation#GO:0050867;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of signaling#GO:0023057;regulation of myeloid cell differentiation#GO:0045637;regulation of signaling#GO:0023051;regulation of bone resorption#GO:0045124;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;regulation of multicellular organismal development#GO:2000026;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of lymphocyte activation#GO:0051249;positive regulation of leukocyte activation#GO:0002696;positive regulation of cell differentiation#GO:0045597;positive regulation of immune system process#GO:0002684;regulation of B cell activation#GO:0050864;positive regulation of biological process#GO:0048518;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;negative regulation of signal transduction#GO:0009968 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000011989.4|UniProtKB=F7B9B7 F7B9B7 C3orf18 PTHR15868:SF0 SIMILAR TO RIKEN CDNA 6430571L13 GENE, SIMILAR TO G20 PROTEIN SIMILAR TO HUMAN CHROMOSOME 3 OPEN READING FRAME 18 MONDO|Ensembl=ENSMODG00000009290.4|UniProtKB=F6YXK6 F6YXK6 CYGB PTHR46783:SF2 CYTOGLOBIN CYTOGLOBIN heme binding#GO:0020037;binding#GO:0005488;catalytic activity#GO:0003824;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491 MONDO|Ensembl=ENSMODG00000014171.5|UniProtKB=F7F8P8 F7F8P8 KBTBD11 PTHR45972:SF3 BTB_2 DOMAIN-CONTAINING PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 11 MONDO|Ensembl=ENSMODG00000047407.1|UniProtKB=A0A5F8HBD1 A0A5F8HBD1 LOC100618455 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014573.4|UniProtKB=F7ASS2 F7ASS2 AKAP8 PTHR12190:SF6 A-KINASE ANCHOR PROTEIN AKAP 8 A-KINASE ANCHOR PROTEIN 8 protein kinase A binding#GO:0051018;binding#GO:0005488;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515 chromosome segregation#GO:0007059;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;nuclear division#GO:0000280;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000044158.1|UniProtKB=F6YSQ3 F6YSQ3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000039711.1|UniProtKB=A0A5F8GJ44 A0A5F8GJ44 PTHR14467:SF0 ARV1 PROTEIN ARV1 glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000000361.2|UniProtKB=F6R9J6 F6R9J6 CHCHD1 PTHR31278:SF2 CHCHD1 SMALL RIBOSOMAL SUBUNIT PROTEIN MS37 MONDO|Ensembl=ENSMODG00000021177.4|UniProtKB=H9H7W1 H9H7W1 KLHL4 PTHR24412:SF74 KELCH PROTEIN KELCH-LIKE PROTEIN 4 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000023529.2|UniProtKB=F7GLF0 F7GLF0 PTHR12817:SF3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;TRAPP complex#GO:0030008;Golgi apparatus subcompartment#GO:0098791;intracellular protein-containing complex#GO:0140535;cis-Golgi network#GO:0005801;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000006278.4|UniProtKB=A0A5F8HCP3 A0A5F8HCP3 CCP110 PTHR13594:SF1 CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cell projection organization#GO:0030030;organelle assembly#GO:0070925;centriole replication#GO:0007099;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000047194.1|UniProtKB=A0A5F8G8U8 A0A5F8G8U8 PTHR45880:SF1 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000000829.3|UniProtKB=A0A5F8GDE4 A0A5F8GDE4 PTHR24302:SF38 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A5 oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987;steroid metabolic process#GO:0008202 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000023040.2|UniProtKB=F7DY90 F7DY90 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000004974.4|UniProtKB=F6US22 F6US22 INSIG1 PTHR15301:SF11 INSULIN-INDUCED GENE 1 INSULIN-INDUCED GENE 1 PROTEIN cellular response to peptide hormone stimulus#GO:0071375;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;localization#GO:0051179;cell communication#GO:0007154;macromolecule localization#GO:0033036;regulation of signal transduction#GO:0009966;cellular response to nitrogen compound#GO:1901699;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;regulation of response to stress#GO:0080134;intracellular protein localization#GO:0008104;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;small molecule metabolic process#GO:0044281;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;regulation of cellular response to stress#GO:0080135;negative regulation of intracellular signal transduction#GO:1902532;response to stress#GO:0006950;response to hormone#GO:0009725;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;response to lipid#GO:0033993;response to chemical#GO:0042221;metabolic process#GO:0008152;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;SREBP signaling pathway#GO:0032933;response to peptide hormone#GO:0043434;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;lipid biosynthetic process#GO:0008610;regulation of response to stimulus#GO:0048583;cholesterol metabolic process#GO:0008203;cellular response to insulin stimulus#GO:0032869;negative regulation of cellular process#GO:0048523;secondary alcohol biosynthetic process#GO:1902653;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;secondary alcohol metabolic process#GO:1902652;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;cellular localization#GO:0051641;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;negative regulation of signal transduction#GO:0009968;cellular response to lipid#GO:0071396;cholesterol biosynthetic process#GO:0006695;alcohol metabolic process#GO:0006066 cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000050322.1|UniProtKB=A0A5F8G9S4 A0A5F8G9S4 CIMAP1D PTHR21580:SF62 SHIPPO-1-RELATED PROTEIN CIMAP1D cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;male gamete generation#GO:0048232;cellular process#GO:0009987;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;spermatid differentiation#GO:0048515;spermatid development#GO:0007286;sexual reproduction#GO:0019953;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000015511.4|UniProtKB=F6VYU4 F6VYU4 PTHR24147:SF53 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN 26 MONDO|Ensembl=ENSMODG00000001828.4|UniProtKB=A0A5F8H171 A0A5F8H171 MTSS1 PTHR15708:SF10 ACTIN BUNDLING/MISSING IN METASTASIS-RELATED PROTEIN MTSS 1 lipid binding#GO:0008289;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;binding#GO:0005488 regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;adherens junction organization#GO:0034332;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;membrane organization#GO:0061024;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;positive regulation of actin filament bundle assembly#GO:0032233;cell-cell junction maintenance#GO:0045217;cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;regulation of actin filament-based process#GO:0032970 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000005106.6|UniProtKB=F6TCM0 F6TCM0 DEPDC4 PTHR16206:SF10 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 4 scaffold/adaptor protein#PC00226 MONDO|Gene=UBL4B|UniProtKB=Q19KS6 Q19KS6 UBL4B PTHR47905:SF1 UBIQUITIN-LIKE PROTEIN 4B UBIQUITIN-LIKE PROTEIN 4B MONDO|Ensembl=ENSMODG00000002593.4|UniProtKB=A0A5F8GUC1 A0A5F8GUC1 DRAM1 PTHR21324:SF11 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED DNA DAMAGE-REGULATED AUTOPHAGY MODULATOR PROTEIN 1 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of catabolic process#GO:0009894;regulation of autophagy#GO:0010506;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 lysosome#GO:0005764;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013875.4|UniProtKB=F6TPY2 F6TPY2 PTHR46875:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5 regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;B cell activation#GO:0042113;signal transduction#GO:0007165;cellular process#GO:0009987;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;regulation of immune response#GO:0050776;cell activation#GO:0001775;immune system process#GO:0002376;cell communication#GO:0007154;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048508.1|UniProtKB=A0A5F8GDD0 A0A5F8GDD0 PTHR10806:SF12 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11C catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;peptidase complex#GO:1905368 serine protease#PC00203 Vasopressin synthesis#P04395>Signal Peptidase#P04589;Endothelin signaling pathway#P00019>signal peptidase#P00573 MONDO|Ensembl=ENSMODG00000005473.5|UniProtKB=F7CG09 F7CG09 MINK1 PTHR48015:SF11 SERINE/THREONINE-PROTEIN KINASE TAO MISSHAPEN-LIKE KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;intracellular signaling cassette#GO:0141124;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000045226.1|UniProtKB=A0A5F8HBM5 A0A5F8HBM5 MCHR1 PTHR24229:SF91 NEUROPEPTIDES RECEPTOR MELANIN-CONCENTRATING HORMONE RECEPTOR 1 neuropeptide binding#GO:0042923;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000027616.2|UniProtKB=K7DZQ0 K7DZQ0 LOC103101657 PTHR23226:SF425 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 24 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006827.3|UniProtKB=F6PG89 F6PG89 ANKRD1 PTHR24126:SF7 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;transcription factor binding#GO:0008134;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000051129.1|UniProtKB=A0A5F8GUD0 A0A5F8GUD0 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000008221.4|UniProtKB=F6ZY74 F6ZY74 DAAM1 PTHR45725:SF16 FORMIN HOMOLOGY 2 FAMILY MEMBER DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 1 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actomyosin#GO:0042641;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin filament bundle#GO:0032432;intracellular organelle#GO:0043229;stress fiber#GO:0001725;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000003658.3|UniProtKB=F7AZ53 F7AZ53 LOC100020127 PTHR23023:SF81 DIMETHYLANILINE MONOOXYGENASE DIMETHYLANILINE MONOOXYGENASE [N-OXIDE-FORMING] 6-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;oxidoreductase activity#GO:0016491 biosynthetic process#GO:0009058;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000001747.4|UniProtKB=F6WZT1 F6WZT1 TMEM171 PTHR31617:SF0 TRANSMEMBRANE PROTEIN 171 TRANSMEMBRANE PROTEIN 171 MONDO|Ensembl=ENSMODG00000048250.1|UniProtKB=A0A5F8GAM4 A0A5F8GAM4 LOC100013113 PTHR12411:SF902 CYSTEINE PROTEASE FAMILY C1-RELATED PROCATHEPSIN L peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000021167.4|UniProtKB=F6XX83 F6XX83 SEPTIN7 PTHR18884:SF137 SEPTIN SEPTIN-7 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cell cycle process#GO:0022402;cell division#GO:0051301;cellular process#GO:0009987;macromolecule localization#GO:0033036;cell cycle#GO:0007049;cytokinesis#GO:0000910;intracellular protein localization#GO:0008104;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640 microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;cell cortex#GO:0005938;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000013385.4|UniProtKB=F7D8S1 F7D8S1 TREH PTHR23403:SF1 TREHALASE TREHALASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152;oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000006566.4|UniProtKB=F7BUI6 F7BUI6 PTHR31763:SF2 HYPOTHETICAL PROTEIN LOC689766 PROTEIN SPMIP3 MONDO|Ensembl=ENSMODG00000014002.4|UniProtKB=A0A5F8GTL0 A0A5F8GTL0 LOC100024870 PTHR46605:SF1 TUMOR NECROSIS FACTOR RECEPTOR DEATH DOMAIN-CONTAINING MEMBRANE PROTEIN NRADD coreceptor activity#GO:0015026;signaling receptor activity#GO:0038023;binding#GO:0005488;death receptor activity#GO:0005035;transmembrane signaling receptor activity#GO:0004888;growth factor binding#GO:0019838;molecular transducer activity#GO:0060089;protein binding#GO:0005515 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000430.4|UniProtKB=A0A5F8GUN3 A0A5F8GUN3 LOC100015925 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000047931.1|UniProtKB=A0A5F8HDD3 A0A5F8HDD3 LOC103103461 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017744.3|UniProtKB=F7EKV7 F7EKV7 HYPK PTHR31184:SF2 HUNTINGTIN-INTERACTING PROTEIN K FAMILY MEMBER HUNTINGTIN-INTERACTING PROTEIN K negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;negative regulation of programmed cell death#GO:0043069;regulation of protein stability#GO:0031647;regulation of biological process#GO:0050789;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 MONDO|Ensembl=ENSMODG00000021588.2|UniProtKB=Q65CI3 Q65CI3 MT-ND5 PTHR42829:SF4 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000020235.4|UniProtKB=A0A5F8GG86 A0A5F8GG86 RASA1 PTHR10194:SF146 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 1 GTPase-activating protein#PC00257 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Ras#P00886;EGF receptor signaling pathway#P00018>GAP#P00546;PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646;Interleukin signaling pathway#P00036>RasGAP#P00975;Angiogenesis#P00005>GAP#P00205;Angiogenesis#P00005>RasGAP#P00190 MONDO|Ensembl=ENSMODG00000006836.3|UniProtKB=F6PFZ5 F6PFZ5 FBXW9 PTHR19855:SF34 WD40 REPEAT PROTEIN 12, 37 F-BOX_WD REPEAT-CONTAINING PROTEIN 9 MONDO|Ensembl=ENSMODG00000015679.3|UniProtKB=F7EHP1 F7EHP1 YPEL3 PTHR13848:SF102 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 3 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000017791.5|UniProtKB=F7CZV3 F7CZV3 MCM9 PTHR11630:SF48 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA HELICASE MCM9 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000004915.4|UniProtKB=F7BH34 F7BH34 PARN PTHR15092:SF44 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 POLY(A)-SPECIFIC RIBONUCLEASE PARN hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;3'-5'-RNA exonuclease activity#GO:0000175;binding#GO:0005488;nucleic acid binding#GO:0003676;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;RNA binding#GO:0003723;hydrolase activity#GO:0016787 regulation of mRNA metabolic process#GO:1903311;RNA 3'-end processing#GO:0031123;positive regulation of mRNA metabolic process#GO:1903313;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;RNA processing#GO:0006396;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000000946.3|UniProtKB=F7F7P9 F7F7P9 PTHR11073:SF14 CALRETICULIN AND CALNEXIN CALRETICULIN calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to chemical#GO:0042221;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein folding#GO:0006457;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000020705.3|UniProtKB=F7BAZ3 F7BAZ3 MTTP PTHR13024:SF1 MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN, LARGE SUBUNIT MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN LARGE SUBUNIT lipoprotein metabolic process#GO:0042157;homeostatic process#GO:0042592;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;cellular process#GO:0009987;cholesterol homeostasis#GO:0042632;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;chemical homeostasis#GO:0048878 endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;basal part of cell#GO:0045178;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 MONDO|Ensembl=ENSMODG00000011383.4|UniProtKB=F6SP71 F6SP71 LRR1 PTHR45752:SF153 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT PROTEIN 1 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004799.4|UniProtKB=A0A5F8G776 A0A5F8G776 SNAP25 PTHR19305:SF5 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 25 binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484;protein binding#GO:0005515 neurotransmitter secretion#GO:0007269;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic vesicle membrane organization#GO:0048499;membrane fusion#GO:0061025;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle fusion#GO:0006906;anterograde trans-synaptic signaling#GO:0098916;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;synaptic vesicle fusion to presynaptic active zone membrane#GO:0031629;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;organelle membrane fusion#GO:0090174;neurotransmitter transport#GO:0006836;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;exocytic process#GO:0140029;vesicle fusion to plasma membrane#GO:0099500;regulated exocytosis#GO:0045055;signaling#GO:0023052;export from cell#GO:0140352;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;secretion by cell#GO:0032940;cellular localization#GO:0051641 cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Synaptic vesicle trafficking#P05734>SNAP-25#P05778;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996 MONDO|Ensembl=ENSMODG00000004940.4|UniProtKB=F7ATT0 F7ATT0 PLS3 PTHR19961:SF32 FIMBRIN/PLASTIN PLASTIN-3 molecular adaptor activity#GO:0060090;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015 cellular process#GO:0009987;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin filament#GO:0005884;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;membrane#GO:0016020;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin filament bundle#GO:0032432;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000013696.4|UniProtKB=F6QNY2 F6QNY2 SLC37A3 PTHR43184:SF33 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B SUGAR PHOSPHATE EXCHANGER 3 xenobiotic transmembrane transporter activity#GO:0042910;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 transporter#PC00227 MONDO|Ensembl=ENSMODG00000014601.3|UniProtKB=F7A3W4 F7A3W4 OXNAD1 PTHR46505:SF1 OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1 OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000037596.1|UniProtKB=A0A5F8GWM8 A0A5F8GWM8 LOC100027853 PTHR26452:SF310 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000013784.5|UniProtKB=F6TUU1 F6TUU1 SIK3 PTHR24346:SF42 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE SIK3 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000048961.1|UniProtKB=A0A5F8HDY2 A0A5F8HDY2 PTHR23055:SF101 CALCIUM BINDING PROTEINS VISININ-LIKE PROTEIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000033772.2|UniProtKB=A0A5F8HE15 A0A5F8HE15 PTHR35825:SF2 CASEIN KINASE II SUBUNIT ALPHA PRIME-INTERACTING PROTEIN CASEIN KINASE II SUBUNIT ALPHA'-INTERACTING PROTEIN MONDO|Ensembl=ENSMODG00000006916.4|UniProtKB=F6PSB4 F6PSB4 USP20 PTHR21646:SF13 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 20 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of protein stability#GO:0031647;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000000828.4|UniProtKB=F6S8V5 F6S8V5 NKD2 PTHR22611:SF1 PROTEIN NAKED CUTICLE PROTEIN NAKED CUTICLE HOMOLOG 2 negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;negative regulation of Wnt signaling pathway#GO:0030178;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Wnt signaling pathway#P00057>Naked#P01427 MONDO|Ensembl=ENSMODG00000046034.1|UniProtKB=A0A5F8GLB6 A0A5F8GLB6 PTHR11387:SF12 CYTOCHROME C OXIDASE SUBUNIT 6B CYTOCHROME C OXIDASE SUBUNIT 6B2 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxidase#PC00175 MONDO|Ensembl=ENSMODG00000011455.3|UniProtKB=A0A5F8H593 A0A5F8H593 OSGEPL1 PTHR11735:SF6 TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE, MITOCHONDRIAL mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000000546.4|UniProtKB=F6XMH9 F6XMH9 CDC42EP1 PTHR15344:SF7 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 1 enzyme binding#GO:0019899;binding#GO:0005488;small GTPase binding#GO:0031267;protein binding#GO:0005515 regulation of supramolecular fiber organization#GO:1902903;cellular response to stimulus#GO:0051716;regulation of developmental process#GO:0050793;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;positive regulation of cell projection organization#GO:0031346;intracellular signal transduction#GO:0035556;regulation of cell projection assembly#GO:0060491;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cell projection organization#GO:0031344;regulation of actin filament-based process#GO:0032970;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;Rho protein signal transduction#GO:0007266;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;intracellular signaling cassette#GO:0141124;positive regulation of cellular component biogenesis#GO:0044089;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000024091.2|UniProtKB=A0A5F8H053 A0A5F8H053 PTHR46948:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P38 RIBONUCLEASE P PROTEIN SUBUNIT P38 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000046290.1|UniProtKB=A0A5F8GY21 A0A5F8GY21 TMED9 PTHR22811:SF37 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 9 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 Golgi organization#GO:0007030;cellular component organization#GO:0016043;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000039610.1|UniProtKB=A0A5F8HKT0 A0A5F8HKT0 PTHR24390:SF290 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 184 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000016876.4|UniProtKB=A0A5F8G8Q6 A0A5F8G8Q6 GBE1 PTHR43651:SF15 1,4-ALPHA-GLUCAN-BRANCHING ENZYME 1,4-ALPHA-GLUCAN-BRANCHING ENZYME catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757 carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;glycogen metabolic process#GO:0005977;glucan biosynthetic process#GO:0009250;polysaccharide biosynthetic process#GO:0000271;energy reserve metabolic process#GO:0006112;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;glycogen biosynthetic process#GO:0005978;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 amylase#PC00048 MONDO|Ensembl=ENSMODG00000004604.1|UniProtKB=F6Y4K0 F6Y4K0 GINS2 PTHR12772:SF0 DNA REPLICATION COMPLEX GINS PROTEIN PSF2 DNA REPLICATION COMPLEX GINS PROTEIN PSF2 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987 protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;GINS complex#GO:0000811;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;DNA replication preinitiation complex#GO:0031261;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000018502.4|UniProtKB=F7B4F8 F7B4F8 TMEM30A PTHR10926:SF17 CELL CYCLE CONTROL PROTEIN 50 CELL CYCLE CONTROL PROTEIN 50A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;lipid transport#GO:0006869 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000044262.1|UniProtKB=A0A5F8HI65 A0A5F8HI65 MFAP5 PTHR16485:SF6 MICROFIBRILLAR-ASSOCIATED PROTEIN 2 MICROFIBRILLAR-ASSOCIATED PROTEIN 5 sensory system development#GO:0048880;multicellular organismal process#GO:0032501;embryo development#GO:0009790;sensory organ development#GO:0007423;developmental process#GO:0032502;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure morphogenesis#GO:0009653;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887;visual system development#GO:0150063;animal gross anatomical part developmental process#GO:0160108;embryonic organ development#GO:0048568;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;interstitial matrix#GO:0005614;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;extracellular region#GO:0005576;supramolecular fiber#GO:0099512 MONDO|Ensembl=ENSMODG00000050206.1|UniProtKB=A0A5F8G6V5 A0A5F8G6V5 TMEM117 PTHR31226:SF1 TRANSMEMBRANE PROTEIN 117 TRANSMEMBRANE PROTEIN 117 apoptotic signaling pathway#GO:0097190;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;biological regulation#GO:0065007;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;intracellular signal transduction#GO:0035556;intrinsic apoptotic signaling pathway#GO:0097193;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;signaling#GO:0023052;intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress#GO:0070059;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 MONDO|Ensembl=ENSMODG00000000501.4|UniProtKB=F6TU35 F6TU35 GALNT1 PTHR11675:SF123 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 1 UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000013434.4|UniProtKB=F7GIM6 F7GIM6 RPS11 PTHR10744:SF9 40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US17 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000049544.1|UniProtKB=A0A5F8G2N7 A0A5F8G2N7 LOC100027508 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010996.3|UniProtKB=F7A1L5 F7A1L5 DRAXIN PTHR28610:SF1 DRAXIN DRAXIN regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;system development#GO:0048731;anatomical structure development#GO:0048856;axon guidance#GO:0007411;axon development#GO:0061564;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;plasma membrane bounded cell projection organization#GO:0120036;brain development#GO:0007420;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;neuron projection morphogenesis#GO:0048812;central nervous system neuron differentiation#GO:0021953;negative regulation of cellular process#GO:0048523;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of Wnt signaling pathway#GO:0030111;cell projection organization#GO:0030030;cell differentiation#GO:0030154;central nervous system development#GO:0007417;forebrain development#GO:0030900;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;negative regulation of cell communication#GO:0010648;axonogenesis#GO:0007409;cellular process#GO:0009987;neuron projection development#GO:0031175;regulation of canonical Wnt signaling pathway#GO:0060828;head development#GO:0060322;cell morphogenesis involved in neuron differentiation#GO:0048667;negative regulation of signal transduction#GO:0009968;nervous system development#GO:0007399;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000002349.4|UniProtKB=F7GLK5 F7GLK5 MSMO1 PTHR11863:SF225 STEROL DESATURASE METHYLSTEROL MONOOXYGENASE 1 monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;secondary alcohol biosynthetic process#GO:1902653;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;primary metabolic process#GO:0044238 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 oxidase#PC00175 MONDO|Ensembl=ENSMODG00000024365.2|UniProtKB=F7AHA8 F7AHA8 PTHR10036:SF11 CD59 GLYCOPROTEIN LY6_PLAUR DOMAIN-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000024960.1|UniProtKB=F6UC97 F6UC97 SFT2D3 PTHR23137:SF36 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN SFT2C MONDO|Ensembl=ENSMODG00000011608.4|UniProtKB=F6UHI9 F6UHI9 PTHR24103:SF676 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000017840.3|UniProtKB=F6Z8U2 F6Z8U2 CALHM5 PTHR32261:SF8 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 5 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000007446.4|UniProtKB=F7DVV8 F7DVV8 LOC107650137 PTHR24376:SF85 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 600-RELATED regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000019664.4|UniProtKB=F6TUQ5 F6TUQ5 ERBIN PTHR45752:SF47 LEUCINE-RICH REPEAT-CONTAINING ERBIN signal transduction#GO:0007165;cellular process#GO:0009987;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;regulation of defense response#GO:0031347;cell communication#GO:0007154;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;intracellular signal transduction#GO:0035556 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007228.3|UniProtKB=F6WCD1 F6WCD1 CCNB1IP1 PTHR14305:SF0 E3 UBIQUITIN-PROTEIN LIGASE CCNB1IP1 E3 UBIQUITIN-PROTEIN LIGASE CCNB1IP1 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 reproductive process#GO:0022414;homologous recombination#GO:0035825;cellular component organization#GO:0016043;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cell cycle process#GO:0022402;reciprocal homologous recombination#GO:0140527;organelle fission#GO:0048285;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;sexual reproduction#GO:0019953;nucleobase-containing compound metabolic process#GO:0006139;organelle organization#GO:0006996;cellular process#GO:0009987;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA recombination#GO:0006310 chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;synaptonemal structure#GO:0099086;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000003149.4|UniProtKB=A0A5F8GML6 A0A5F8GML6 PTHR18945:SF764 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3E molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215 transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;response to chemical#GO:0042221;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;response to nitrogen compound#GO:1901698;trans-synaptic signaling#GO:0099537;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;establishment of localization#GO:0051234;transport#GO:0006810;cellular response to nitrogen compound#GO:1901699;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;signaling receptor complex#GO:0043235;cation channel complex#GO:0034703;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000039348.1|UniProtKB=A0A5F8HGI2 A0A5F8HGI2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024624.1|UniProtKB=F6Q9S1 F6Q9S1 RNF182 PTHR46675:SF2 E3 UBIQUITIN-PROTEIN LIGASE RNF182 E3 UBIQUITIN-PROTEIN LIGASE RNF182 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000007292.4|UniProtKB=A0A5F8GRM0 A0A5F8GRM0 LOC100030871 PTHR12659:SF4 RHO-TYPE GTPASE ACTIVATING PROTEIN RHO-GAP DOMAIN-CONTAINING PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 actin filament-based process#GO:0030029;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cell communication#GO:0010646;actin cytoskeleton organization#GO:0030036;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 GTPase-activating protein#PC00257;G-protein modulator#PC00022 PDGF signaling pathway#P00047>Rho#P01174 MONDO|Ensembl=ENSMODG00000042585.1|UniProtKB=A0A5F8G355 A0A5F8G355 MAP2K3 PTHR48013:SF21 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 3 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>MKK3#P01367;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891;Apoptosis signaling pathway#P00006>MKK3#P00314;EGF receptor signaling pathway#P00018>MKK3,6#P00540;Integrin signalling pathway#P00034>MEK#P00925;Ras Pathway#P04393>MKK3/6#P04568;FGF signaling pathway#P00021>MKK3,6#P00625;Gonadotropin-releasing hormone receptor pathway#P06664>MKK3/6#P06805;p38 MAPK pathway#P05918>MKK3#P06036;Oxidative stress response#P00046>MKK3/6#P01121 MONDO|Ensembl=ENSMODG00000002080.4|UniProtKB=F6UZJ2 F6UZJ2 DYRK3 PTHR24058:SF35 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;positive regulation of cell cycle#GO:0045787;regulation of cell cycle G2/M phase transition#GO:1902749;organelle organization#GO:0006996;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;protein-containing complex disassembly#GO:0032984;regulation of cell cycle#GO:0051726;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411 nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000017341.3|UniProtKB=F6WFJ5 F6WFJ5 AJM1 PTHR21517:SF3 APICAL JUNCTION COMPONENT 1 HOMOLOG APICAL JUNCTION COMPONENT 1 HOMOLOG cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell-cell junction organization#GO:0045216;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cell junction#GO:0030054;anchoring junction#GO:0070161;apical junction complex#GO:0043296 MONDO|Ensembl=ENSMODG00000014032.4|UniProtKB=F6URF0 F6URF0 DRC7 PTHR35249:SF2 DYNEIN REGULATORY COMPLEX SUBUNIT 7 DYNEIN REGULATORY COMPLEX SUBUNIT 7 cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;sperm motility#GO:0097722;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000024518.1|UniProtKB=F7AK41 F7AK41 LOC100028478 PTHR48002:SF97 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007839.3|UniProtKB=F7ETB2 F7ETB2 PSMA3 PTHR11599:SF10 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-3 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 nucleus#GO:0005634;proteasome complex#GO:0000502;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 MONDO|Ensembl=ENSMODG00000016899.3|UniProtKB=F6XIC9 F6XIC9 PTHR23415:SF29 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT-RELATED kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic cell cycle phase transition#GO:0044772;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770 nucleus#GO:0005634;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006384.4|UniProtKB=F7G2F0 F7G2F0 BBOF1 PTHR14845:SF5 COILED-COIL DOMAIN-CONTAINING 166 BASAL BODY-ORIENTATION FACTOR 1 MONDO|Ensembl=ENSMODG00000018333.4|UniProtKB=A0A5F8H8A6 A0A5F8H8A6 ADCY5 PTHR45627:SF7 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 5 lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016;catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849 cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;cyclic nucleotide biosynthetic process#GO:0009190;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cyclic purine nucleotide metabolic process#GO:0052652;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;signal transduction#GO:0007165;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 adenylate cyclase#PC00043 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AC#P00841;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;GABA-B receptor II signaling#P05731>AC#P05760;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 MONDO|Ensembl=ENSMODG00000018583.4|UniProtKB=F7FD92 F7FD92 HPX PTHR22917:SF9 HEMOPEXIN DOMAIN-CONTAINING PROTEIN HEMOPEXIN extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000039609.1|UniProtKB=A0A5F8GHZ2 A0A5F8GHZ2 SCG5 PTHR12738:SF0 NEUROENDOCRINE PROTEIN 7B2 NEUROENDOCRINE PROTEIN 7B2 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789;regulation of secretion#GO:0051046;regulation of hormone secretion#GO:0046883;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of signaling#GO:0023051 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000047039.1|UniProtKB=A0A5F8GQG7 A0A5F8GQG7 PTHR10083:SF328 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED TISSUE FACTOR PATHWAY INHIBITOR molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 Blood coagulation#P00011>TFPI#P00417 MONDO|Ensembl=ENSMODG00000015463.4|UniProtKB=F6S2Z2 F6S2Z2 NSMCE1 PTHR20973:SF0 NON-SMC ELEMENT 1-RELATED NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842 response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000040889.1|UniProtKB=F7BQQ0 F7BQQ0 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000025763.2|UniProtKB=F7G3E9 F7G3E9 CMC2 PTHR22977:SF1 COX ASSEMBLY MITOCHONDRIAL PROTEIN COX ASSEMBLY MITOCHONDRIAL PROTEIN 2 HOMOLOG mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000001445.1|UniProtKB=F7BBZ1 F7BBZ1 PTHR13596:SF1 SMALL EDRK-RICH FACTOR 1 SMALL EDRK-RICH FACTOR 1 MONDO|Ensembl=ENSMODG00000024541.2|UniProtKB=F7FT91 F7FT91 LOC103094817 PTHR12941:SF13 ER MEMBRANE PROTEIN COMPLEX ER MEMBRANE PROTEIN COMPLEX SUBUNIT 8 protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104 localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996 cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546 MONDO|Ensembl=ENSMODG00000044791.1|UniProtKB=A0A5F8GUC2 A0A5F8GUC2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000013008.4|UniProtKB=A0A5F8H0D4 A0A5F8H0D4 FUCA1 PTHR10030:SF37 ALPHA-L-FUCOSIDASE TISSUE ALPHA-L-FUCOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;glycosyl compound catabolic process#GO:1901658;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 glycosidase#PC00110;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000019840.4|UniProtKB=H9H7I2 H9H7I2 PTHR11686:SF56 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 1 PROENZYME-RELATED peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 regulation of immune system process#GO:0002682;catabolic process#GO:0009056;modified amino acid metabolic process#GO:0006575;regulation of biological process#GO:0050789;peptide metabolic process#GO:0006518;glutathione metabolic process#GO:0006749;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;sulfur compound catabolic process#GO:0044273;regulation of response to stress#GO:0080134;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000028545.2|UniProtKB=K7E368 K7E368 PTHR19277:SF94 PENTRAXIN NEURONAL PENTRAXIN RECEPTOR scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007755.3|UniProtKB=A0A5F8H2Q9 A0A5F8H2Q9 NAA30 PTHR45896:SF1 N-ALPHA-ACETYLTRANSFERASE 30 N-ALPHA-ACETYLTRANSFERASE 30 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248 metabolite interconversion enzyme#PC00262;acetyltransferase#PC00038;transferase#PC00220 MONDO|Ensembl=ENSMODG00000013483.4|UniProtKB=F7F946 F7F946 GLRX3 PTHR10293:SF74 GLUTAREDOXIN FAMILY MEMBER GLUTAREDOXIN-3 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;iron-sulfur cluster assembly#GO:0016226;intracellular monoatomic ion homeostasis#GO:0006873;cellular component organization#GO:0016043;inorganic ion homeostasis#GO:0098771 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000037963.1|UniProtKB=A0A5F8G6S8 A0A5F8G6S8 PTHR26453:SF257 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004168.4|UniProtKB=F6QQ05 F6QQ05 LENG8 PTHR12436:SF4 80 KDA MCM3-ASSOCIATED PROTEIN LEUKOCYTE RECEPTOR CLUSTER MEMBER 8 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005963.3|UniProtKB=F6WF28 F6WF28 LRRC36 PTHR23311:SF6 HEAT SHOCK REGULATED 2 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 36 MONDO|Ensembl=ENSMODG00000042471.1|UniProtKB=A0A5F8HIF9 A0A5F8HIF9 PTHR25952:SF256 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000023466.2|UniProtKB=F6T6Z6 F6T6Z6 PTHR26452:SF930 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000025487.2|UniProtKB=F6QZ18 F6QZ18 PTHR20904:SF0 INDUCIBLE T-CELL COSTIMULATOR ICOS INDUCIBLE T-CELL COSTIMULATOR positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;regulation of leukocyte cell-cell adhesion#GO:1903037;developmental process#GO:0032502;positive regulation of cell adhesion#GO:0045785;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of lymphocyte activation#GO:0051251;anatomical structure development#GO:0048856;system development#GO:0048731;positive regulation of cell-cell adhesion#GO:0022409;cell-cell adhesion#GO:0098609;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;regulation of multicellular organismal process#GO:0051239;positive regulation of leukocyte activation#GO:0002696;multicellular organism development#GO:0007275;regulation of leukocyte activation#GO:0002694;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of lymphocyte activation#GO:0051249;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;immune system development#GO:0002520 MONDO|Ensembl=ENSMODG00000016525.3|UniProtKB=H9H6Y1 H9H6Y1 PTHR11799:SF14 PARAOXONASE SERUM PARAOXONASE_LACTONASE 3 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;response to toxic substance#GO:0009636;response to chemical#GO:0042221;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000001252.4|UniProtKB=F7CJ60 F7CJ60 FGA PTHR47221:SF3 FIBRINOGEN ALPHA CHAIN FIBRINOGEN ALPHA CHAIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of hemostasis#GO:1900046;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;negative regulation of wound healing#GO:0061045;response to wounding#GO:0009611;homotypic cell-cell adhesion#GO:0034109;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;regulation of coagulation#GO:0050818;regulation of response to stimulus#GO:0048583;negative regulation of blood coagulation#GO:0030195;regulation of response to stress#GO:0080134;blood coagulation#GO:0007596;platelet activation#GO:0030168;macromolecule metabolic process#GO:0043170;positive regulation of cell adhesion#GO:0045785;primary metabolic process#GO:0044238;hemostasis#GO:0007599;negative regulation of multicellular organismal process#GO:0051241;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;blood coagulation, fibrin clot formation#GO:0072378;cell activation#GO:0001775;protein metabolic process#GO:0019538;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;coagulation#GO:0050817;response to stress#GO:0006950;cell-cell adhesion#GO:0098609;regulation of response to wounding#GO:1903034;positive regulation of cell-cell adhesion#GO:0022409;regulation of multicellular organismal process#GO:0051239;negative regulation of response to external stimulus#GO:0032102;regulation of response to external stimulus#GO:0032101;protein maturation#GO:0051604;gene expression#GO:0010467;fibrinolysis#GO:0042730;platelet aggregation#GO:0070527;metabolic process#GO:0008152;negative regulation of response to wounding#GO:1903035;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of wound healing#GO:0061041;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;regulation of blood coagulation#GO:0030193;negative regulation of hemostasis#GO:1900047;cell adhesion#GO:0007155;wound healing#GO:0042060;regulation of biological quality#GO:0065008;negative regulation of coagulation#GO:0050819;protein activation cascade#GO:0072376 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 Plasminogen activating cascade#P00050>Fibrin C-terminal truncation#P01258;Plasminogen activating cascade#P00050>Fibrin#P01253;Blood coagulation#P00011>Fibrin monomer#P00418;Blood coagulation#P00011>Fibrin polymer cross-linked#P00443;Blood coagulation#P00011>Fibrinogen#P00406 MONDO|Gene=PRL|UniProtKB=O62819 O62819 PRL PTHR11417:SF5 SOMATOTROPIN,PROLACTIN PROLACTIN signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of secretion#GO:0051047;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;regulation of multicellular organismal development#GO:2000026;multi-multicellular organism process#GO:0044706;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of transport#GO:0051049;animal organ development#GO:0048513;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of transport#GO:0051050;anatomical structure development#GO:0048856;regulation of secretion#GO:0051046;cell communication#GO:0007154;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;reproductive process#GO:0022414;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>Prolactin#P06789 MONDO|Ensembl=ENSMODG00000004686.3|UniProtKB=F6TRA4 F6TRA4 AWAT2 PTHR12317:SF12 DIACYLGLYCEROL O-ACYLTRANSFERASE ACYL-COA WAX ALCOHOL ACYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 neutral lipid metabolic process#GO:0006638;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;primary metabolic process#GO:0044238 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;transferase#PC00220 MONDO|Ensembl=ENSMODG00000025774.2|UniProtKB=A0A5F8H192 A0A5F8H192 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000029452.2|UniProtKB=K7E0H8 K7E0H8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000011529.5|UniProtKB=F6QXY6 F6QXY6 FAM171A2 PTHR31626:SF3 SUSHI DOMAIN-CONTAINING PROTEIN PROTEIN FAM171A2 MONDO|Ensembl=ENSMODG00000018747.3|UniProtKB=F7EF50 F7EF50 PIAS3 PTHR10782:SF10 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS3 catalytic activity#GO:0003824;transferase activity#GO:0016740;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;acyltransferase activity#GO:0016746;molecular function inhibitor activity#GO:0140678;ubiquitin-like protein ligase activity#GO:0061659 post-translational protein modification#GO:0043687;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;protein sumoylation#GO:0016925;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;metabolic process#GO:0008152;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of DNA-templated transcription#GO:0045892;regulation of signaling#GO:0023051;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228 ubiquitin-protein ligase#PC00234 JAK/STAT signaling pathway#P00038>PIAS#P01031;Interferon-gamma signaling pathway#P00035>PIAS#P00958 MONDO|Ensembl=ENSMODG00000018105.5|UniProtKB=A0A5F8GUL2 A0A5F8GUL2 ZNF384 PTHR24376:SF130 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 384 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006555.4|UniProtKB=F7BUX2 F7BUX2 PTHR10026:SF45 CYCLIN CYCLIN-L2 enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 kinase activator#PC00138;kinase modulator#PC00140 MONDO|Ensembl=ENSMODG00000013057.4|UniProtKB=F7FQG1 F7FQG1 BRD7 PTHR22881:SF12 BROMODOMAIN CONTAINING PROTEIN BROMODOMAIN-CONTAINING PROTEIN 7 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000001829.4|UniProtKB=F7CKB1 F7CKB1 ALCAM PTHR11973:SF2 CELL SURFACE GLYCOPROTEIN MUC18-RELATED CD166 ANTIGEN anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;generation of neurons#GO:0048699;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000018917.3|UniProtKB=A0A5F8GT19 A0A5F8GT19 PTHR47362:SF1 ACYL-COENZYME A THIOESTERASE THEM5 ACYL-COENZYME A THIOESTERASE THEM5 catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617;acyl-CoA hydrolase activity#GO:0016289;deacylase activity#GO:0160215;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;hydrolase activity#GO:0016787 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013 hydrolase#PC00121;esterase#PC00097 MONDO|Ensembl=ENSMODG00000012822.4|UniProtKB=F7DD82 F7DD82 PTHR13547:SF23 RIBONUCLEASE P MITOCHONDRIAL RIBONUCLEASE P CATALYTIC SUBUNIT ribonuclease P activity#GO:0004526;catalytic activity, acting on a tRNA#GO:0140101;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540 macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular protein-containing complex#GO:0140535;endonuclease complex#GO:1905348;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000016745.3|UniProtKB=F6YL96 F6YL96 STUB1 PTHR46803:SF5 E3 UBIQUITIN-PROTEIN LIGASE CHIP E3 UBIQUITIN-PROTEIN LIGASE CHIP protein-folding chaperone binding#GO:0051087;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515 response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of proteolysis#GO:0030162;response to misfolded protein#GO:0051788;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular response to misfolded protein#GO:0071218;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;regulation of cellular process#GO:0050794;cellular response to topologically incorrect protein#GO:0035967;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 Z disc#GO:0030018;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;I band#GO:0031674;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Parkinson disease#P00049>CHIP#P01214 MONDO|Ensembl=ENSMODG00000017372.3|UniProtKB=F6VIF5 F6VIF5 EFCAB10 PTHR21847:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cilium movement#GO:0003341;cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;radial spoke#GO:0001534;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000015403.5|UniProtKB=F6T4A8 F6T4A8 GLIS3 PTHR45718:SF1 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS ZINC FINGER PROTEIN GLIS3 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000009152.4|UniProtKB=F7B0M8 F7B0M8 SLC46A3 PTHR23507:SF9 ZGC:174356 LYSOSOMAL PROTON-COUPLED STEROID CONJUGATE AND BILE ACID SYMPORTER SLC46A3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;vacuolar transmembrane transport#GO:0034486;establishment of localization#GO:0051234 membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuole#GO:0005773;cytoplasm#GO:0005737;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000027834.2|UniProtKB=K7E2A0 K7E2A0 PTHR22663:SF21 RING FINGER PROTEIN NARYA-RELATED E3 SUMO-PROTEIN LIGASE RNF212-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 cellular process#GO:0009987;organelle organization#GO:0006996;homologous chromosome pairing at meiosis#GO:0007129;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;cell cycle process#GO:0022402;cell cycle#GO:0007049;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;reproductive process#GO:0022414;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;organelle fission#GO:0048285 synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;synaptonemal structure#GO:0099086;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000008665.4|UniProtKB=A0A5F8G613 A0A5F8G613 METTL8 PTHR22809:SF3 METHYLTRANSFERASE-RELATED TRNA N(3)-CYTIDINE METHYLTRANSFERASE METTL8, MITOCHONDRIAL S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175 methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000037074.1|UniProtKB=A0A5F8GDR6 A0A5F8GDR6 PTHR11362:SF82 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4 protease inhibitor#PC00191 FGF signaling pathway#P00021>RKIP#P00630;EGF receptor signaling pathway#P00018>RKIP#P00548 MONDO|Ensembl=ENSMODG00000017756.4|UniProtKB=K7E623 K7E623 MANEAL PTHR13572:SF2 ENDO-ALPHA-1,2-MANNOSIDASE GLYCOPROTEIN ENDO-ALPHA-1,2-MANNOSIDASE-LIKE PROTEIN hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 MONDO|Ensembl=ENSMODG00000021255.3|UniProtKB=F6TIT0 F6TIT0 CPB1 PTHR11705:SF20 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE B metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000000342.2|UniProtKB=F6RV04 F6RV04 COX7A2L PTHR10510:SF2 CYTOCHROME C OXIDASE POLYPEPTIDE 7A CYTOCHROME C OXIDASE SUBUNIT 7A2-LIKE, MITOCHONDRIAL molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;metabolic process#GO:0008152;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091 membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 oxidase#PC00175;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000044679.1|UniProtKB=A0A5F8HAD6 A0A5F8HAD6 HAUS5 PTHR28588:SF1 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 5 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 5 cellular process#GO:0009987;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;HAUS complex#GO:0070652;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000007786.4|UniProtKB=F7A9R0 F7A9R0 TM9SF2 PTHR10766:SF55 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 2 cellular process#GO:0009987;localization within membrane#GO:0051668;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000003711.3|UniProtKB=F7FA24 F7FA24 PTHR18034:SF3 CELL CYCLE CONTROL PROTEIN CWF22-RELATED PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000011376.2|UniProtKB=F6SPJ3 F6SPJ3 PTHR12010:SF2 40S RIBOSOMAL PROTEIN S29 SMALL RIBOSOMAL SUBUNIT PROTEIN US14 transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;structural constituent of ribosome#GO:0003735;zinc ion binding#GO:0008270;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000020799.4|UniProtKB=H9H9P6 H9H9P6 MIGA1 PTHR21508:SF3 MITOGUARDIN MITOGUARDIN 1 mitochondrion organization#GO:0007005;organelle fusion#GO:0048284;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;mitochondrial fusion#GO:0008053;organelle organization#GO:0006996;cellular component organization#GO:0016043 MONDO|Ensembl=ENSMODG00000024347.1|UniProtKB=F7B4V4 F7B4V4 LOC100022251 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037541.1|UniProtKB=A0A5F8H6B6 A0A5F8H6B6 PTHR23331:SF4 CXYORF1 WAS_WASL-INTERACTING PROTEIN FAMILY MEMBER 3 vesicle-mediated transport#GO:0016192;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;exocytosis#GO:0006887;intracellular transport#GO:0046907;transport#GO:0006810;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;endocytic recycling#GO:0032456;cytosolic transport#GO:0016482;export from cell#GO:0140352;cellular component organization#GO:0016043;cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;localization within membrane#GO:0051668 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000014160.4|UniProtKB=A0A5F8GXR4 A0A5F8GXR4 ELP6 PTHR16184:SF6 ELONGATOR COMPLEX PROTEIN 6 ELONGATOR COMPLEX PROTEIN 6 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;elongator holoenzyme complex#GO:0033588;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000014260.4|UniProtKB=A0A5F8H8M0 A0A5F8H8M0 SH3YL1 PTHR15629:SF46 SH3YL1 PROTEIN SH3 DOMAIN-CONTAINING YSC84-LIKE PROTEIN 1 small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167 regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of biological process#GO:0050789;regulation of cell projection assembly#GO:0060491;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344 ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;ruffle#GO:0001726;cell projection membrane#GO:0031253;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000021005.4|UniProtKB=F6RJB6 F6RJB6 CHAF1B PTHR15271:SF4 CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;nucleosome organization#GO:0034728;protein-containing complex organization#GO:0043933 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000016015.3|UniProtKB=A0A5F8HF68 A0A5F8HF68 SMUG1 PTHR13235:SF2 SINGLE-STRAND SELECTIVE MONOFUNCTIONAL URACIL DNA GLYCOSYLASE SINGLE-STRAND SELECTIVE MONOFUNCTIONAL URACIL DNA GLYCOSYLASE DNA N-glycosylase activity#GO:0019104;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654 DNA glycosylase#PC00010 MONDO|Ensembl=ENSMODG00000019275.4|UniProtKB=F6SHX7 F6SHX7 FAM174A PTHR28607:SF1 EXPRESSED PROTEIN MEMBRANE PROTEIN FAM174A MONDO|Ensembl=ENSMODG00000000184.4|UniProtKB=F6TFW8 F6TFW8 INO80 PTHR45685:SF2 HELICASE SRCAP-RELATED CHROMATIN-REMODELING ATPASE INO80 histone binding#GO:0042393;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515 cellular process#GO:0009987;response to stress#GO:0006950;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;response to stimulus#GO:0050896;cellular response to stress#GO:0033554 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Ino80 complex#GO:0031011;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000013908.2|UniProtKB=F6VBQ0 F6VBQ0 TMEM147 PTHR12869:SF0 SMALL SEVEN TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN BOS COMPLEX SUBUNIT TMEM147 MONDO|Ensembl=ENSMODG00000019678.3|UniProtKB=H9H7E5 H9H7E5 BNIP3 PTHR15186:SF4 RE48077P BCL2_ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 process utilizing autophagic mechanism#GO:0061919;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;programmed cell death#GO:0012501;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;positive regulation of apoptotic process#GO:0043065;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;autophagy#GO:0006914;cellular process#GO:0009987;organelle organization#GO:0006996;reticulophagy#GO:0061709;biological regulation#GO:0065007;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;macroautophagy#GO:0016236 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;outer membrane#GO:0019867;organelle outer membrane#GO:0031968;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;nucleus#GO:0005634;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000012066.4|UniProtKB=F7G546 F7G546 PALM3 PTHR47528:SF1 PARALEMMIN-3 PARALEMMIN-3 response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;response to external stimulus#GO:0009605;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;negative regulation of response to cytokine stimulus#GO:0060761;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to bacterium#GO:0009617;negative regulation of signal transduction#GO:0009968;response to lipid#GO:0033993;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of response to cytokine stimulus#GO:0060759;response to biotic stimulus#GO:0009607;response to lipopolysaccharide#GO:0032496;regulation of cytokine-mediated signaling pathway#GO:0001959;cell surface receptor signaling pathway#GO:0007166;negative regulation of cytokine-mediated signaling pathway#GO:0001960;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;negative regulation of signaling#GO:0023057 MONDO|Ensembl=ENSMODG00000048845.1|UniProtKB=A0A5F8GBV7 A0A5F8GBV7 LEP PTHR11724:SF1 LEPTIN LEPTIN signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515 response to nutrient levels#GO:0031667;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;lipid metabolic process#GO:0006629;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cytokine-mediated signaling pathway#GO:0019221;energy reserve metabolic process#GO:0006112;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to cytokine#GO:0034097;response to chemical#GO:0042221;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;positive regulation of signaling#GO:0023056;regulation of biological quality#GO:0065008;response to peptide#GO:1901652 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 MONDO|Ensembl=ENSMODG00000015377.4|UniProtKB=A0A5F8GAE2 A0A5F8GAE2 RCL1 PTHR11096:SF1 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;cyclase activity#GO:0009975;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;nuclease activity#GO:0004518 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000021230.4|UniProtKB=F6U0L5 F6U0L5 RASA2 PTHR10194:SF21 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 2 GTPase-activating protein#PC00257 FGF signaling pathway#P00021>RasGAP#P00646;PDGF signaling pathway#P00047>RasGAP#P01152;EGF receptor signaling pathway#P00018>GAP#P00546 MONDO|Ensembl=ENSMODG00000003753.4|UniProtKB=F7DUZ7 F7DUZ7 MYO5B PTHR13140:SF356 MYOSIN UNCONVENTIONAL MYOSIN-VB macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;membrane#GO:0016020;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000038904.1|UniProtKB=A0A5F8GU18 A0A5F8GU18 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000005657.4|UniProtKB=F6YVY8 F6YVY8 PTHR11792:SF20 ARRESTIN BETA-ARRESTIN-2 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of MAPK cascade#GO:0043408;import into cell#GO:0098657;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;receptor internalization#GO:0031623;negative regulation of signal transduction#GO:0009968;regulation of ERK1 and ERK2 cascade#GO:0070372;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;nervous system process#GO:0050877;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;sensory perception of pain#GO:0019233;endocytosis#GO:0006897;positive regulation of intracellular signal transduction#GO:1902533;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;transport#GO:0006810;negative regulation of cellular process#GO:0048523;receptor-mediated endocytosis#GO:0006898;system process#GO:0003008;establishment of localization#GO:0051234;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;localization#GO:0051179;positive regulation of signal transduction#GO:0009967;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>beta-ARR2#P05923;CCKR signaling map#P06959>Beta-arrestin-1/2#P07187;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>beta-arrestin#P00723;Wnt signaling pathway#P00057>beta-arrestin#P01456;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>beta-arrestin#P00880 MONDO|Ensembl=ENSMODG00000020222.4|UniProtKB=F7FXI7 F7FXI7 CETN3 PTHR23050:SF325 CALCIUM BINDING PROTEIN CENTRIN-3 metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;microtubule binding#GO:0008017;calcium ion binding#GO:0005509;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000039160.1|UniProtKB=A0A5F8H8P9 A0A5F8H8P9 PTHR16675:SF67 MHC CLASS I-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000025399.2|UniProtKB=F6RMM9 F6RMM9 LINGO1 PTHR24373:SF31 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT AND IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING NOGO RECEPTOR-INTERACTING PROTEIN 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004172.4|UniProtKB=A0A5F8HI94 A0A5F8HI94 COL23A1 PTHR37456:SF4 SI:CH211-266K2.1 COLLAGEN TYPE XXIII ALPHA 1 CHAIN MONDO|Ensembl=ENSMODG00000011147.4|UniProtKB=F7AP07 F7AP07 PTHR23176:SF104 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 27 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 MONDO|Ensembl=ENSMODG00000006307.3|UniProtKB=F7BRK5 F7BRK5 RAF1 PTHR44329:SF22 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED RAF PROTO-ONCOGENE SERINE_THREONINE-PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;MAP kinase kinase kinase activity#GO:0004709;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Ras Pathway#P04393>Raf#P04556;CCKR signaling map#P06959>c-RAF / RAF1#P07213;CCKR signaling map#P06959>RAF1#P07085;T cell activation#P00053>Raf#P01311;VEGF signaling pathway#P00056>Raf#P01417;PDGF signaling pathway#P00047>Raf#P01161;Endothelin signaling pathway#P00019>Raf-1#P00587;Interleukin signaling pathway#P00036>Raf#P00983;Integrin signalling pathway#P00034>Raf#P00924;B cell activation#P00010>Raf#P00381;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Raf#P00893;Angiogenesis#P00005>Raf#P00243;EGF receptor signaling pathway#P00018>Raf-1#P00560;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Raf1#P05928;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Raf-1#P00843;FGF signaling pathway#P00021>Raf-1#P00643;Gonadotropin-releasing hormone receptor pathway#P06664>c-Raf#P06832 MONDO|Ensembl=ENSMODG00000014564.4|UniProtKB=F7GBZ1 F7GBZ1 LOC100024120 PTHR10334:SF521 CYSTEINE-RICH SECRETORY PROTEIN-RELATED C-TYPE LECTIN DOMAIN FAMILY 18 MEMBER A-RELATED polysaccharide binding#GO:0030247;binding#GO:0005488;carbohydrate binding#GO:0030246 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000004614.4|UniProtKB=F6Y3F6 F6Y3F6 PRKAG2 PTHR13780:SF122 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-2 protein binding#GO:0005515;enzyme regulator activity#GO:0030234;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;molecular function regulator activity#GO:0098772;nucleotide binding#GO:0000166 positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;cellular response to stress#GO:0033554;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of carbohydrate biosynthetic process#GO:0043255;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of carbohydrate metabolic process#GO:0006109;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;regulation of primary metabolic process#GO:0080090;cellular response to glucose starvation#GO:0042149;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830 MONDO|Ensembl=ENSMODG00000048118.1|UniProtKB=A0A5F8GZP9 A0A5F8GZP9 PTHR24377:SF1028 IP01015P-RELATED ZINC FINGER PROTEIN 84 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009107.3|UniProtKB=F7FCA6 F7FCA6 TMBIM4 PTHR23291:SF50 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 4 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085;calcium channel activity#GO:0005262;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000019096.4|UniProtKB=A0A5F8HIZ7 A0A5F8HIZ7 PTHR10720:SF1 HEME OXYGENASE HEME OXYGENASE 1 binding#GO:0005488;tetrapyrrole binding#GO:0046906;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 response to oxidative stress#GO:0006979;porphyrin-containing compound metabolic process#GO:0006778;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;heme metabolic process#GO:0042168;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular process#GO:0009987;response to stress#GO:0006950;pigment metabolic process#GO:0042440 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000018531.4|UniProtKB=F7GL36 F7GL36 NELL2 PTHR24042:SF0 NEL HOMOLOG PROTEIN KINASE C-BINDING PROTEIN NELL2 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;glycosaminoglycan binding#GO:0005539;protein binding#GO:0005515;heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367 extracellular region#GO:0005576;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000025017.2|UniProtKB=F6SW40 F6SW40 LOC100014733 PTHR11406:SF0 PHOSPHOGLYCERATE KINASE PHOSPHOGLYCERATE KINASE small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;phosphoglycerate kinase activity#GO:0004618;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotide binding#GO:0000166;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;purine ribonucleoside triphosphate binding#GO:0035639;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;kinase activity#GO:0016301;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;ribonucleoside diphosphate metabolic process#GO:0009185;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;oxoacid metabolic process#GO:0043436;nicotinamide nucleotide metabolic process#GO:0046496;gluconeogenesis#GO:0006094;ATP metabolic process#GO:0046034;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;nucleobase-containing compound catabolic process#GO:0034655;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;small molecule biosynthetic process#GO:0044283;energy derivation by oxidation of organic compounds#GO:0015980;monocarboxylic acid metabolic process#GO:0032787;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;pyruvate metabolic process#GO:0006090;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate biosynthetic process#GO:0016051;ADP catabolic process#GO:0046032;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphoglycerate kinase#P00671 MONDO|Ensembl=ENSMODG00000039114.1|UniProtKB=A0A5F8GRF9 A0A5F8GRF9 RAB5IF PTHR12906:SF0 PROTEIN C20ORF24 RAB5-INTERACTING PROTEIN GEL COMPLEX SUBUNIT OPTI MONDO|Ensembl=ENSMODG00000048956.1|UniProtKB=K7E113 K7E113 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000002446.4|UniProtKB=F7DZ98 F7DZ98 IST1 PTHR12161:SF5 IST1 FAMILY MEMBER IST1 HOMOLOG localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036 MONDO|Ensembl=ENSMODG00000024036.3|UniProtKB=F7D339 F7D339 PTHR48483:SF2 INTERLEUKIN-27 SUBUNIT BETA INTERLEUKIN-27 SUBUNIT BETA protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 leukocyte activation#GO:0045321;T cell activation#GO:0042110;cellular process#GO:0009987;lymphocyte proliferation#GO:0046651;mononuclear cell proliferation#GO:0032943;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;immune system process#GO:0002376;T cell proliferation#GO:0042098;cell population proliferation#GO:0008283;cell activation#GO:0001775;leukocyte proliferation#GO:0070661 MONDO|Ensembl=ENSMODG00000008027.5|UniProtKB=F6Y3I4 F6Y3I4 ZKSCAN8 PTHR23226:SF75 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 8 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000047514.1|UniProtKB=A0A5F8HB30 A0A5F8HB30 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000036644.1|UniProtKB=A0A5F8GQ83 A0A5F8GQ83 monDomV1R1274 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000046384.1|UniProtKB=A0A5F8GG19 A0A5F8GG19 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003050.4|UniProtKB=F6PP33 F6PP33 SNTA1 PTHR10554:SF6 SYNTROPHIN ALPHA-1-SYNTROPHIN channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108 muscle contraction#GO:0006936;system process#GO:0003008;heart contraction#GO:0060047;regulation of membrane potential#GO:0042391;cardiac muscle cell contraction#GO:0086003;actin filament-based movement#GO:0030048;cellular process#GO:0009987;biological regulation#GO:0065007;blood circulation#GO:0008015;cardiac muscle cell action potential involved in contraction#GO:0086002;multicellular organismal process#GO:0032501;cardiac muscle contraction#GO:0060048;actin filament-based process#GO:0030029;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;action potential#GO:0001508;muscle system process#GO:0003012;heart process#GO:0003015;striated muscle contraction#GO:0006941;actin-mediated cell contraction#GO:0070252 membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;neuromuscular junction#GO:0031594;sarcolemma#GO:0042383;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000009749.5|UniProtKB=A0A5F8HEZ9 A0A5F8HEZ9 ABLIM1 PTHR24213:SF18 ACTIN-BINDING LIM PROTEIN ACTIN-BINDING LIM PROTEIN 1 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;lamellipodium assembly#GO:0030032;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin filament bundle#GO:0032432;intracellular organelle#GO:0043229;stress fiber#GO:0001725;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actomyosin#GO:0042641;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 Axon guidance mediated by netrin#P00009>Ablim#P00358 MONDO|Ensembl=ENSMODG00000037248.1|UniProtKB=A0A5F8HHW4 A0A5F8HHW4 FAM43A PTHR11232:SF36 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PROTEIN FAM43A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000025091.3|UniProtKB=F6V8C1 F6V8C1 RPS24 PTHR10496:SF7 40S RIBOSOMAL PROTEIN S24 SMALL RIBOSOMAL SUBUNIT PROTEIN ES24 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000024997.3|UniProtKB=A0A5F8G493 A0A5F8G493 LOC130454523 PTHR24356:SF170 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C ZETA TYPE catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 protein localization to cell periphery#GO:1990778;response to chemical#GO:0042221;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;cellular localization#GO:0051641;establishment or maintenance of cell polarity#GO:0007163;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;protein localization to membrane#GO:0072657;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;intracellular protein localization#GO:0008104;cellular response to insulin stimulus#GO:0032869;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;macromolecule localization#GO:0033036;cell communication#GO:0007154;localization#GO:0051179;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;localization within membrane#GO:0051668;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;protein localization to plasma membrane#GO:0072659;establishment of cell polarity#GO:0030010;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868 non-receptor serine/threonine protein kinase#PC00167 Endothelin signaling pathway#P00019>PKC#P00568;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKCzeta#P00829;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKC#P00861;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109 MONDO|Ensembl=ENSMODG00000011318.4|UniProtKB=F6WJ15 F6WJ15 PBRM1 PTHR16062:SF19 SWI/SNF-RELATED PROTEIN POLYBROMO-1 binding#GO:0005488;chromatin binding#GO:0003682 chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RSC-type complex#GO:0016586;ATPase complex#GO:1904949;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000046057.1|UniProtKB=A0A5F8HBK1 A0A5F8HBK1 TMEM238 PTHR28613:SF5 SI:CH211-232M10.4-RELATED TRANSMEMBRANE PROTEIN 238 MONDO|Ensembl=ENSMODG00000000962.4|UniProtKB=F7F7G1 F7F7G1 DUSP12 PTHR45848:SF4 DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000019512.3|UniProtKB=F6VDA7 F6VDA7 RBCK1 PTHR22770:SF35 UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED RANBP-TYPE AND C3HC4-TYPE ZINC FINGER-CONTAINING PROTEIN 1 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;modification-dependent protein catabolic process#GO:0019941;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of signaling#GO:0023056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000016671.3|UniProtKB=A0A5F8H6H0 A0A5F8H6H0 LRRTM4 PTHR24373:SF283 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT TRANSMEMBRANE NEURONAL PROTEIN 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017474.4|UniProtKB=F7FF42 F7FF42 PTHR10807:SF52 MYOTUBULARIN-RELATED MYOTUBULARIN RELATED PROTEIN 9 LIKE, PSEUDO hydrolase activity#GO:0016787;protein binding#GO:0005515;enzyme binding#GO:0019899;phosphatase binding#GO:0019902;binding#GO:0005488;protein phosphatase binding#GO:0019903;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 organophosphate metabolic process#GO:0019637;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;biological regulation#GO:0065007;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid dephosphorylation#GO:0046839;regulation of biological process#GO:0050789;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;phospholipid metabolic process#GO:0006644;phosphatidylinositol dephosphorylation#GO:0046856;dephosphorylation#GO:0016311;negative regulation of catabolic process#GO:0009895 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000002397.3|UniProtKB=A0A5F8HEA6 A0A5F8HEA6 CCDC163 PTHR34533:SF2 TRANSMEMBRANE PROTEIN CCDC163 COILED-COIL DOMAIN CONTAINING 163 MONDO|Ensembl=ENSMODG00000023571.2|UniProtKB=F7G1H4 F7G1H4 PTHR23089:SF55 HISTIDINE TRIAD HIT PROTEIN ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT1 catalytic activity#GO:0003824;hydrolase activity#GO:0016787 nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleotide metabolic process#GO:0009150;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 nucleotide phosphatase#PC00173 MONDO|Ensembl=ENSMODG00000016467.3|UniProtKB=H9H6V4 H9H6V4 SDHAF3 PTHR13137:SF6 DC11 ACN9 HOMOLOG SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 3, MITOCHONDRIAL protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex II assembly#GO:0034553;cellular component assembly#GO:0022607 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000008118.5|UniProtKB=F7FV49 F7FV49 CTSF PTHR12411:SF444 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN F cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000021203.4|UniProtKB=F6UH70 F6UH70 FAM124B PTHR14715:SF2 FAM124 DOMAIN-CONTAINING PROTEIN-RELATED PROTEIN FAM124B intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000015604.3|UniProtKB=A0A5F8H250 A0A5F8H250 MAT2A PTHR11964:SF73 S-ADENOSYLMETHIONINE SYNTHETASE S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 biosynthetic process#GO:0009058;cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 nucleotidyltransferase#PC00174;transferase#PC00220 S-adenosylmethionine biosynthesis#P02773>S-Adenosyl methionine synthetase#P03143 MONDO|Ensembl=ENSMODG00000016787.4|UniProtKB=A0A5F8HC86 A0A5F8HC86 PTHR16188:SF6 PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14C enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;protein serine/threonine phosphatase inhibitor activity#GO:0004865;phosphatase regulator activity#GO:0019208;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857 phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000017905.4|UniProtKB=A0A5F8GPV1 A0A5F8GPV1 FYN PTHR24418:SF44 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FYN catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;binding#GO:0005488;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672 activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of immune response#GO:0050778;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;immune response-activating signaling pathway#GO:0002757;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of immune response#GO:0050776;immune system process#GO:0002376;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 Integrin signalling pathway#P00034>Fyn#P00942;Cadherin signaling pathway#P00012>Fyn#P00464;Parkinson disease#P00049>Src kinase#P01230;Axon guidance mediated by semaphorins#P00007>Fyn#P00335;Parkinson disease#P00049>Fyn kinase#P01235 MONDO|Ensembl=ENSMODG00000004211.5|UniProtKB=F6XQE0 F6XQE0 PTBP2 PTHR15592:SF16 MATRIN 3/NUCLEAR PROTEIN 220-RELATED POLYPYRIMIDINE TRACT-BINDING PROTEIN 2 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000023053.2|UniProtKB=F7C9S0 F7C9S0 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000009859.4|UniProtKB=F6VVB2 F6VVB2 PTHR46788:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 5 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 5 cell motility#GO:0048870;reproductive process#GO:0022414;cellular process#GO:0009987;sperm motility#GO:0097722 membraneless organelle#GO:0043228;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000008079.4|UniProtKB=F6YJ80 F6YJ80 RPN1 PTHR21049:SF0 RIBOPHORIN I DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 1 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000020911.4|UniProtKB=H9H7S3 H9H7S3 PTHR31367:SF0 CYTOSOLIC 5'-NUCLEOTIDASE 1 FAMILY MEMBER CYTOSOLIC 5'-NUCLEOTIDASE 1B hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine nucleoside metabolic process#GO:0042278;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;adenosine metabolic process#GO:0046085 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000015235.4|UniProtKB=F6UKB3 F6UKB3 ZNF800 PTHR21020:SF2 ZINC FINGER PROTEIN 800 ZINC FINGER PROTEIN 800 MONDO|Ensembl=ENSMODG00000010153.4|UniProtKB=F6TB56 F6TB56 CCDC141 PTHR42757:SF44 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 141 cell adhesion#GO:0007155;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000008511.4|UniProtKB=F7FG24 F7FG24 VIP PTHR11213:SF5 GLUCAGON-FAMILY NEUROPEPTIDE VIP PEPTIDES hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;binding#GO:0005488;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;neuropeptide hormone activity#GO:0005184 positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;nitrogen compound transport#GO:0071705;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of localization#GO:0032879;positive regulation of intracellular signal transduction#GO:1902533;transport#GO:0006810;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;export from cell#GO:0140352;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;localization#GO:0051179;positive regulation of signaling#GO:0023056;secretion#GO:0046903;secretion by cell#GO:0032940;regulation of protein localization#GO:0032880;organic hydroxy compound transport#GO:0015850;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 neuropeptide#PC00162 MONDO|Ensembl=ENSMODG00000018292.4|UniProtKB=F6PW83 F6PW83 SPACA1 PTHR47223:SF1 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 1 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 1 organelle assembly#GO:0070925;spermatid differentiation#GO:0048515;cellular component assembly involved in morphogenesis#GO:0010927;sexual reproduction#GO:0019953;spermatid development#GO:0007286;acrosome assembly#GO:0001675;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;cellular component organization#GO:0016043;developmental process involved in reproduction#GO:0003006;anatomical structure morphogenesis#GO:0009653;germ cell development#GO:0007281;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;cellular anatomical entity morphogenesis#GO:0032989;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;vesicle organization#GO:0016050;anatomical structure formation involved in morphogenesis#GO:0048646;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;male gamete generation#GO:0048232;endomembrane system organization#GO:0010256 vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;acrosomal membrane#GO:0002080 MONDO|Ensembl=ENSMODG00000019682.3|UniProtKB=F6TTD6 F6TTD6 NDUFA8 PTHR13344:SF0 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 8 respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000043607.1|UniProtKB=K7E3X8 K7E3X8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024229.2|UniProtKB=F6VII0 F6VII0 PTHR16231:SF5 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 6 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;tumor necrosis factor-mediated signaling pathway#GO:0033209;response to peptide#GO:1901652;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;response to tumor necrosis factor#GO:0034612;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000014908.4|UniProtKB=A0A5F8HGX0 A0A5F8HGX0 AP1M1 PTHR10529:SF257 AP COMPLEX SUBUNIT MU AP-1 COMPLEX SUBUNIT MU-1 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;establishment of localization#GO:0051234;Golgi to vacuole transport#GO:0006896;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;coated membrane#GO:0048475;intracellular organelle#GO:0043229;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;trans-Golgi network transport vesicle membrane#GO:0012510;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;AP-1 adaptor complex#GO:0030121;trans-Golgi network transport vesicle#GO:0030140;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;membrane protein complex#GO:0098796 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000012729.4|UniProtKB=A0A5F8HFH4 A0A5F8HFH4 LRRC28 PTHR16083:SF81 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 28 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000038517.1|UniProtKB=F6STC9 F6STC9 PTHR26453:SF9 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10A4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010798.4|UniProtKB=A0A5F8GHT5 A0A5F8GHT5 SORCS3 PTHR12106:SF10 SORTILIN RELATED VPS10 DOMAIN-CONTAINING RECEPTOR SORCS3 transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892 membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cytoplasm#GO:0005737;plasma membrane#GO:0005886;Golgi apparatus#GO:0005794;synaptic membrane#GO:0097060;cell junction#GO:0030054;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;intracellular membrane-bounded organelle#GO:0043231;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;postsynaptic density membrane#GO:0098839;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000025661.2|UniProtKB=A0ACM8QHQ2 A0ACM8QHQ2 KISS1 PTHR16955:SF6 METASTASIS-SUPPRESSOR KISS-1 METASTASIS-SUPPRESSOR KISS-1 G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488;neuropeptide receptor binding#GO:0071855;protein binding#GO:0005515 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of system process#GO:0044057;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;positive regulation of signaling#GO:0023056;regulation of secretion#GO:0051046;cell communication#GO:0007154;regulation of hormone secretion#GO:0046883;regulation of signaling#GO:0023051;positive regulation of secretion#GO:0051047;positive regulation of hormone secretion#GO:0046887;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;positive regulation of multicellular organismal process#GO:0051240;regulation of hormone levels#GO:0010817;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000044838.1|UniProtKB=A0A5F8HGB4 A0A5F8HGB4 CLRN1 PTHR31548:SF4 CLARIN CLARIN-1 multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;system process#GO:0003008;nervous system process#GO:0050877;neuromuscular process#GO:0050905;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954 MONDO|Ensembl=ENSMODG00000011871.4|UniProtKB=F7G2U8 F7G2U8 LOC130457235 PTHR31359:SF31 TRANSMEMBRANE PROTEIN 92 TRANSMEMBRANE PROTEIN 92 MONDO|Ensembl=ENSMODG00000004976.4|UniProtKB=F7FKZ3 F7FKZ3 PTHR14611:SF4 TECTONIC FAMILY MEMBER TECTONIC-3 plasma membrane bounded cell projection assembly#GO:0120031;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;signal transduction#GO:0007165;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell projection organization#GO:0030030;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 MONDO|Ensembl=ENSMODG00000005578.4|UniProtKB=H9H8G2 H9H8G2 LOC100028088 PTHR24376:SF85 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 600-RELATED negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000010451.3|UniProtKB=F6YS95 F6YS95 LOC100027551 PTHR45683:SF18 MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 32 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000002689.3|UniProtKB=F7CYE7 F7CYE7 PADI4 PTHR10837:SF3 PEPTIDYLARGININE DEIMINASE PROTEIN-ARGININE DEIMINASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000048522.1|UniProtKB=A0A5F8GKM2 A0A5F8GKM2 PET117 PTHR28163:SF1 PROTEIN PET117 HOMOLOG, MITOCHONDRIAL PROTEIN PET117 HOMOLOG, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000020308.4|UniProtKB=A0A5F8HHX8 A0A5F8HHX8 DAB2 PTHR47695:SF5 PID DOMAIN-CONTAINING PROTEIN DISABLED HOMOLOG 2 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 localization#GO:0051179;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell differentiation#GO:0045595;transport#GO:0006810;regulation of response to stimulus#GO:0048583;positive regulation of developmental process#GO:0051094;negative regulation of cellular process#GO:0048523;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;positive regulation of endocytosis#GO:0045807;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;endocytosis#GO:0006897;regulation of cellular component organization#GO:0051128;positive regulation of cell differentiation#GO:0045597;regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;regulation of localization#GO:0032879;import into cell#GO:0098657;cellular process#GO:0009987;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of multicellular organismal process#GO:0051239;negative regulation of signal transduction#GO:0009968;vesicle-mediated transport#GO:0016192 clathrin-coated pit#GO:0005905;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000008290.4|UniProtKB=F7FTZ1 F7FTZ1 NUP98 PTHR23198:SF6 NUCLEOPORIN NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96 binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of nuclear pore#GO:0017056;RNA binding#GO:0003723;structural molecule activity#GO:0005198 macromolecule localization#GO:0033036;import into nucleus#GO:0051170;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;chromosome organization#GO:0051276;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;protein localization to organelle#GO:0033365;establishment of RNA localization#GO:0051236;telomere localization#GO:0034397;localization#GO:0051179;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;organelle localization#GO:0051640;nucleocytoplasmic transport#GO:0006913;chromosome localization#GO:0050000;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;cellular component organization#GO:0016043;cellular localization#GO:0051641;protein transport#GO:0015031;protein import into nucleus#GO:0006606;telomere tethering at nuclear periphery#GO:0034398 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000042397.1|UniProtKB=A0A5F8GNQ6 A0A5F8GNQ6 PTHR19446:SF479 REVERSE TRANSCRIPTASES RNA-DIRECTED DNA POLYMERASE reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000049737.1|UniProtKB=F7FT11 F7FT11 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000016435.4|UniProtKB=F7ASA8 F7ASA8 AURKA PTHR24350:SF5 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE A transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;regulation of cell cycle#GO:0051726;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;microtubule cytoskeleton organization#GO:0000226;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;spindle pole#GO:0000922;kinetochore#GO:0000776;spindle microtubule#GO:0005876;microtubule#GO:0005874;spindle midzone#GO:0051233;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000045530.1|UniProtKB=A0A5F8G7D3 A0A5F8G7D3 DOK2 PTHR21258:SF14 DOCKING PROTEIN RELATED DOCKING PROTEIN 2 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;binding#GO:0005488;receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dok-R#P00180 MONDO|Ensembl=ENSMODG00000038564.1|UniProtKB=A0A5F8GKD0 A0A5F8GKD0 SMAD3 PTHR13703:SF53 SMAD SMAD FAMILY MEMBER 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;response to transforming growth factor beta#GO:0071559;positive regulation of RNA metabolic process#GO:0051254;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;BMP signaling pathway#GO:0030509;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular response to growth factor stimulus#GO:0071363;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;activin receptor signaling pathway#GO:0032924;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to endogenous stimulus#GO:0009719;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;positive regulation of transcription by RNA polymerase II#GO:0045944;intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292 MONDO|Ensembl=ENSMODG00000028305.2|UniProtKB=K7E0J3 K7E0J3 ELN PTHR24018:SF5 ELASTIN ELASTIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;system development#GO:0048731;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;cellular component organization#GO:0016043;tissue remodeling#GO:0048771;animal organ morphogenesis#GO:0009887;circulatory system development#GO:0072359;developmental process#GO:0032502;vasculature development#GO:0001944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;multicellular organismal process#GO:0032501;heart development#GO:0007507 supramolecular fiber#GO:0099512;extracellular region#GO:0005576;supramolecular complex#GO:0099080;interstitial matrix#GO:0005614;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000003096.4|UniProtKB=F6PIV8 F6PIV8 RPL6 PTHR10715:SF0 60S RIBOSOMAL PROTEIN L6 LARGE RIBOSOMAL SUBUNIT PROTEIN EL6 structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000044250.1|UniProtKB=A0A5F8GDZ2 A0A5F8GDZ2 IER3 PTHR16915:SF0 IMMEDIATE EARLY RESPONSE 3 RADIATION-INDUCIBLE IMMEDIATE-EARLY GENE IEX-1 negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;apoptotic signaling pathway#GO:0097190;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cellular response to stimulus#GO:0051716;cell death#GO:0008219;mitotic DNA damage checkpoint signaling#GO:0044773;programmed cell death#GO:0012501;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular response to stress#GO:0033554;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;intrinsic apoptotic signaling pathway#GO:0097193;regulation of mitotic cell cycle phase transition#GO:1901990;apoptotic process#GO:0006915;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 CCKR signaling map#P06959>IEX1#G06970;CCKR signaling map#P06959>IEX1#P07092;CCKR signaling map#P06959>IEX1#G07263 MONDO|Ensembl=ENSMODG00000016311.4|UniProtKB=A0A5F8GDI8 A0A5F8GDI8 PRKCB PTHR24356:SF158 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C BETA TYPE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Metabotropic glutamate receptor group I pathway#P00041>PKC#P01055;Apoptosis signaling pathway#P00006>PKCs#P00318;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;B cell activation#P00010>PKC#P00373;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Endothelin signaling pathway#P00019>PKC#P00568;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;CCKR signaling map#P06959>PKCbeta#P07177;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKC#P00861 MONDO|Ensembl=ENSMODG00000024122.1|UniProtKB=F6TNJ5 F6TNJ5 MAB21L1 PTHR10656:SF38 CELL FATE DETERMINING PROTEIN MAB21-RELATED NUCLEOTIDYLTRANSFERASE MAB21L1-RELATED intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 transferase#PC00220;nucleotidyltransferase#PC00174 MONDO|Ensembl=ENSMODG00000019764.5|UniProtKB=F6WMM9 F6WMM9 HSPA5 PTHR19375:SF144 HEAT SHOCK PROTEIN 70KDA ENDOPLASMIC RETICULUM CHAPERONE BIP ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111 macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;endoplasmic reticulum unfolded protein response#GO:0030968;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;protein metabolic process#GO:0019538;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;gene expression#GO:0010467;protein maturation#GO:0051604;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;protein refolding#GO:0042026;response to unfolded protein#GO:0006986;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;protein folding#GO:0006457;response to stimulus#GO:0050896;regulation of biological process#GO:0050789 endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum lumen#GO:0005788;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072;Hsp70 family chaperone#PC00027 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 MONDO|Ensembl=ENSMODG00000017852.4|UniProtKB=F6Z7T8 F6Z7T8 FRK PTHR24418:SF468 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FRK catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;non-membrane spanning protein tyrosine kinase activity#GO:0004715;binding#GO:0005488;signaling receptor binding#GO:0005102 cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular developmental process#GO:0048869;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 B cell activation#P00010>Blk#P00390;Integrin signalling pathway#P00034>Src#P00940;Parkinson disease#P00049>Src kinase#P01230;Parkinson disease#P00049>Fyn kinase#P01235;Axon guidance mediated by semaphorins#P00007>Fyn#P00335;Cadherin signaling pathway#P00012>Fyn#P00464 MONDO|Ensembl=ENSMODG00000012723.3|UniProtKB=F6TI17 F6TI17 LOC100017736 PTHR11037:SF12 TRANSCRIPTION FACTOR CP2 GRH_CP2 DB DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000024989.1|UniProtKB=F6U9I5 F6U9I5 PTHR11071:SF490 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000043718.1|UniProtKB=F7FFU1 F7FFU1 LOC100030512 PTHR26451:SF876 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10K2 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000049192.1|UniProtKB=K7E076 K7E076 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001999.4|UniProtKB=F6RHR0 F6RHR0 USP36 PTHR24006:SF653 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 36 cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of programmed cell death#GO:0043067;regulation of protein stability#GO:0031647;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000046439.1|UniProtKB=K7E340 K7E340 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000010972.4|UniProtKB=F7AQD1 F7AQD1 ELAC1 PTHR46018:SF2 ZINC PHOSPHODIESTERASE ELAC PROTEIN 1 ZINC PHOSPHODIESTERASE ELAC PROTEIN 1 nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000005435.5|UniProtKB=A0A5F8H3X9 A0A5F8H3X9 ESYT2 PTHR45761:SF2 EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C EXTENDED SYNAPTOTAGMIN-2 phosphatidylcholine binding#GO:0031210;phospholipid binding#GO:0005543;phosphatidylinositol binding#GO:0035091;lipid binding#GO:0008289;cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000037006.1|UniProtKB=A0A5F8GTY3 A0A5F8GTY3 PTHR34221:SF3 HYPOTHETICAL PROTEIN LOC691189 SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000038062.1|UniProtKB=A0A5F8GF60 A0A5F8GF60 PTHR24393:SF100 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 345-RELATED DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004492.4|UniProtKB=F6VQN3 F6VQN3 SLIT1 PTHR45836:SF3 SLIT HOMOLOG SLIT HOMOLOG 1 PROTEIN protein binding#GO:0005515;heparin binding#GO:0008201;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367;signaling receptor binding#GO:0005102;binding#GO:0005488 cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;taxis#GO:0042330;response to chemical#GO:0042221;cellular process#GO:0009987;neuron projection development#GO:0031175;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon development#GO:0061564;axon guidance#GO:0007411;system development#GO:0048731;anatomical structure development#GO:0048856;chemotaxis#GO:0006935;locomotion#GO:0040011 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 Axon guidance mediated by Slit/Robo#P00008>Slit#P00342 MONDO|Ensembl=ENSMODG00000046598.1|UniProtKB=A0A5F8GCV3 A0A5F8GCV3 PTHR13450:SF4 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L42 LARGE RIBOSOMAL SUBUNIT PROTEIN ML42 membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000038862.1|UniProtKB=A0A5F8GPQ2 A0A5F8GPQ2 FGF6 PTHR11486:SF25 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 6 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;fibroblast growth factor receptor binding#GO:0005104;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;response to fibroblast growth factor#GO:0071774;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000046330.1|UniProtKB=A0A5F8G657 A0A5F8G657 ADCYAP1 PTHR11213:SF1 GLUCAGON-FAMILY NEUROPEPTIDE PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;neuropeptide hormone activity#GO:0005184;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;positive regulation of signal transduction#GO:0009967;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;neuron development#GO:0048666;regulation of protein localization#GO:0032880;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;cell development#GO:0048468;signaling#GO:0023052;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of localization#GO:0032879;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;regulation of ERK1 and ERK2 cascade#GO:0070372;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;neuron projection development#GO:0031175 cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;perikaryon#GO:0043204 neuropeptide#PC00162 Gonadotropin-releasing hormone receptor pathway#P06664>PACAP#G06667;Gonadotropin-releasing hormone receptor pathway#P06664>PACAP#P06800;Gonadotropin-releasing hormone receptor pathway#P06664>PACAP#G06879 MONDO|Ensembl=ENSMODG00000014115.4|UniProtKB=F6Y4R2 F6Y4R2 PTHR18952:SF95 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 4 hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;apical part of cell#GO:0045177;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000000397.3|UniProtKB=F6QNA5 F6QNA5 PTHR12486:SF5 APRATAXIN-RELATED ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000013550.3|UniProtKB=F7C3H3 F7C3H3 STK38 PTHR24356:SF221 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 38 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;establishment or maintenance of cell polarity#GO:0007163;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000006621.3|UniProtKB=F7GER6 F7GER6 MRPS28 PTHR13447:SF2 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN BS1M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000010249.3|UniProtKB=F6W5P1 F6W5P1 OR6K6 PTHR26451:SF132 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 6K6 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000010668.4|UniProtKB=F7CJY9 F7CJY9 ERLIN1 PTHR15351:SF2 ERLIN (ER LIPID RAFT ASSOCIATED PROTEIN) HOMOLOG ERLIN-1 binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934;alcohol binding#GO:0043178;cholesterol binding#GO:0015485;lipid binding#GO:0008289;steroid binding#GO:0005496 macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;SREBP signaling pathway#GO:0032933;biological regulation#GO:0065007;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;protein metabolic process#GO:0019538;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to stimulus#GO:0050896;signaling#GO:0023052;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000013677.4|UniProtKB=F6VFS2 F6VFS2 PTHR45935:SF15 PROTEIN ZBED8-RELATED SCAN DOMAIN-CONTAINING PROTEIN 3 MONDO|Ensembl=ENSMODG00000039979.1|UniProtKB=A0A5F8GEP1 A0A5F8GEP1 NEXMIF PTHR46946:SF1 NEURITE EXTENSION AND MIGRATION FACTOR NEURITE EXTENSION AND MIGRATION FACTOR negative regulation of cell adhesion#GO:0007162;negative regulation of cell-cell adhesion#GO:0022408;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;negative regulation of locomotion#GO:0040013;regulation of cell-substrate adhesion#GO:0010810;negative regulation of cell motility#GO:2000146;regulation of locomotion#GO:0040012;regulation of neuron migration#GO:2001222;negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cell adhesion mediated by integrin#GO:0033628;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of cell motility#GO:2000145;regulation of cell-matrix adhesion#GO:0001952 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000046544.1|UniProtKB=A0A5F8GMT0 A0A5F8GMT0 PTHR28457:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 SIMILAR TO HUMAN CHROMOSOME 8 OPEN READING FRAME 74 MONDO|Ensembl=ENSMODG00000009758.4|UniProtKB=F6WT46 F6WT46 SFI1 PTHR22028:SF4 SFI1 SPINDLE BODY DOMAIN-CONTAINING PROTEIN-RELATED PROTEIN SFI1 HOMOLOG protein binding#GO:0005515;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899 MONDO|Ensembl=ENSMODG00000020218.4|UniProtKB=A0A5F8H8X2 A0A5F8H8X2 POLR3G PTHR15367:SF3 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC7 cellular process#GO:0009987;cell population proliferation#GO:0008283 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000001859.4|UniProtKB=F6SNK3 F6SNK3 SLC41A1 PTHR16228:SF23 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SOLUTE CARRIER FAMILY 41 MEMBER 1 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000017025.4|UniProtKB=A0A5F8G6R7 A0A5F8G6R7 TPD52L2 PTHR19307:SF13 TUMOR PROTEIN D52 TUMOR PROTEIN D54 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000020922.3|UniProtKB=F6W2S9 F6W2S9 PTHR26454:SF18 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C76 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016256.2|UniProtKB=F7C1Y2 F7C1Y2 LOC100013696 PTHR26453:SF23 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13C9 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005798.3|UniProtKB=F6XFA6 F6XFA6 PASD1 PTHR46055:SF4 CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT PAS DOMAIN CONTAINING REPRESSOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;circadian rhythm#GO:0007623;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;rhythmic process#GO:0048511;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;circadian regulation of gene expression#GO:0032922 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000003566.4|UniProtKB=F7G126 F7G126 MMADHC PTHR13192:SF3 MY011 PROTEIN COBALAMIN TRAFFICKING PROTEIN CBLD cellular process#GO:0009987;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000024804.3|UniProtKB=F7FAS6 F7FAS6 ITPRIP PTHR10656:SF8 CELL FATE DETERMINING PROTEIN MAB21-RELATED INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-INTERACTING PROTEIN kinase inhibitor activity#GO:0019210;protein kinase regulator activity#GO:0019887;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;enzyme inhibitor activity#GO:0004857;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 membrane#GO:0016020;cellular anatomical structure#GO:0110165 nucleotidyltransferase#PC00174;transferase#PC00220 MONDO|Ensembl=ENSMODG00000010457.3|UniProtKB=A0A5F8GPC8 A0A5F8GPC8 GPAT4 PTHR23063:SF37 PHOSPHOLIPID ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 4 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000007065.4|UniProtKB=F6UF09 F6UF09 INSYN2B PTHR28682:SF2 INHIBITORY SYNAPTIC FACTOR 2A-RELATED PROTEIN INSYN2B MONDO|Ensembl=ENSMODG00000003560.3|UniProtKB=F7GBB3 F7GBB3 PTHR23212:SF0 BRAIN ACID SOLUBLE PROTEIN 1 BRAIN ACID SOLUBLE PROTEIN 1 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000017488.5|UniProtKB=F7FEQ4 F7FEQ4 MYB PTHR45614:SF5 MYB PROTEIN-RELATED TRANSCRIPTIONAL ACTIVATOR MYB sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;mitotic cell cycle#GO:0000278;positive regulation of RNA metabolic process#GO:0051254;cell cycle#GO:0007049;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000007674.4|UniProtKB=F7FNH2 F7FNH2 TULP4 PTHR16517:SF2 TUBBY-RELATED TUBBY-RELATED PROTEIN 4 macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;localization#GO:0051179 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000029070.2|UniProtKB=K7DZK8 K7DZK8 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000011655.2|UniProtKB=F6YEP9 F6YEP9 TMEM230 PTHR15664:SF27 C20ORF30 PROTEIN TRANSMEMBRANE PROTEIN 230 synaptic vesicle transport#GO:0048489;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;synaptic vesicle localization#GO:0097479;establishment of organelle localization#GO:0051656;establishment of vesicle localization#GO:0051650;organelle localization#GO:0051640;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179 exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell junction#GO:0030054;presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;endomembrane system#GO:0012505;transport vesicle#GO:0030133 MONDO|Ensembl=ENSMODG00000027967.2|UniProtKB=K7E3Q6 K7E3Q6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012046.5|UniProtKB=F7ALF5 F7ALF5 SLC39A10 PTHR12191:SF14 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP10 active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;bicarbonate transmembrane transporter activity#GO:0015106;zinc ion transmembrane transporter activity#GO:0005385;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;transition metal ion transmembrane transporter activity#GO:0046915 intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000013218.4|UniProtKB=A0A5F8GU44 A0A5F8GU44 DNAH8 PTHR10676:SF361 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 8 polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;microtubule motor activity#GO:0003777;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;outer dynein arm assembly#GO:0036158;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;axoneme assembly#GO:0035082;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;microtubule cytoskeleton organization#GO:0000226;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cell motility#GO:0048870;microtubule-based movement#GO:0007018;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043 protein-containing complex#GO:0032991;sperm flagellum#GO:0036126;ciliary plasm#GO:0097014;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;outer dynein arm#GO:0036157;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axonemal dynein complex#GO:0005858;dynein complex#GO:0030286;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;9+2 motile cilium#GO:0097729;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000046854.1|UniProtKB=A0A5F8HJR0 A0A5F8HJR0 PTHR23226:SF425 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 24 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008616.4|UniProtKB=F6PH88 F6PH88 D2HGDH PTHR43716:SF5 D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000003815.3|UniProtKB=A0A5F8GU51 A0A5F8GU51 ADD1 PTHR10672:SF4 ADDUCIN ALPHA-ADDUCIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 regulation of protein depolymerization#GO:1901879;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;regulation of actin filament depolymerization#GO:0030834;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;cellular component organization or biogenesis#GO:0071840;positive regulation of cell differentiation#GO:0045597;regulation of anatomical structure size#GO:0090066;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of epithelial cell differentiation#GO:0030856;regulation of protein-containing complex disassembly#GO:0043244;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519 cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;adherens junction#GO:0005912;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000009993.4|UniProtKB=A0A5F8GSX8 A0A5F8GSX8 CCNA1 PTHR10177:SF254 CYCLINS CYCLIN-A1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887 mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;protein kinase complex#GO:1902911;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;transferase complex#GO:1990234 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin A#P04666 MONDO|Ensembl=ENSMODG00000001601.4|UniProtKB=F7BAK8 F7BAK8 MGAT5B PTHR15075:SF6 ALPHA-MANNOSIDE BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE B glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 transferase#PC00220;glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000005451.4|UniProtKB=F7CGZ0 F7CGZ0 SERPINB7 PTHR11461:SF56 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B7 peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000011746.4|UniProtKB=F7DFD3 F7DFD3 CENPI PTHR48208:SF2 CENTROMERE PROTEIN I CENTROMERE PROTEIN I cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;chromosome segregation#GO:0007059;cellular component assembly#GO:0022607;chromatin organization#GO:0006325;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;kinetochore organization#GO:0051383;organelle fission#GO:0048285;organelle assembly#GO:0070925;nuclear division#GO:0000280;kinetochore assembly#GO:0051382;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402 supramolecular complex#GO:0099080;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;kinetochore#GO:0000776;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000016350.4|UniProtKB=F7F787 F7F787 ADNP PTHR15740:SF1 NEUROPROTECTIVE PEPTIDE-CONTAINING PROTEIN ACTIVITY-DEPENDENT NEUROPROTECTOR HOMEOBOX PROTEIN regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000011905.3|UniProtKB=A0A5F8H3C9 A0A5F8H3C9 PTHR11127:SF2 60S RIBOSOMAL PROTEIN L14 LARGE RIBOSOMAL SUBUNIT PROTEIN EL14 nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000010257.4|UniProtKB=A0A5F8H3F0 A0A5F8H3F0 METTL2A PTHR22809:SF4 METHYLTRANSFERASE-RELATED TRNA N(3)-CYTIDINE METHYLTRANSFERASE METTL2A-RELATED catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;tRNA methyltransferase activity#GO:0008175;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000040681.1|UniProtKB=A0A5F8GWL7 A0A5F8GWL7 LOC100020136 PTHR48002:SF21 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025491.3|UniProtKB=A0A5F8G487 A0A5F8G487 PTHR21937:SF5 CCDC66 DOMAIN-CONTAINING PROTEIN GENE 973-RELATED MONDO|Ensembl=ENSMODG00000010501.5|UniProtKB=A0A5F8H3U4 A0A5F8H3U4 WDR81 PTHR44662:SF1 WD REPEAT-CONTAINING PROTEIN 81 WD REPEAT-CONTAINING PROTEIN 81 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 macroautophagy#GO:0016236;process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056;cellular process#GO:0009987;autophagy#GO:0006914;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000043566.1|UniProtKB=A0A5F8G9N5 A0A5F8G9N5 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000016031.4|UniProtKB=K7E2X3 K7E2X3 PTHR16046:SF11 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR 2 PROTEIN FAM178B MONDO|Ensembl=ENSMODG00000044279.1|UniProtKB=A0A5F8HDR6 A0A5F8HDR6 PTHR46002:SF1 EG:114D9.1 PROTEIN-RELATED CALCINEURIN B HOMOLOGOUS PROTEIN 1 calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of calcineurin-NFAT signaling cascade#GO:0070884;cellular process#GO:0009987;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000027841.2|UniProtKB=F6WTK2 F6WTK2 PTHR24381:SF436 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 768 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025542.2|UniProtKB=A0A5F8H6T5 A0A5F8H6T5 PTHR10068:SF16 BONE MARROW PROTEOGLYCAN BONE MARROW PROTEOGLYCAN extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000037027.1|UniProtKB=A0A5F8H6F6 A0A5F8H6F6 PTHR23232:SF175 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER FAMILY MEMBER 767-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014090.3|UniProtKB=F6R4F1 F6R4F1 BRS3 PTHR45695:SF6 LEUCOKININ RECEPTOR-RELATED BOMBESIN RECEPTOR SUBTYPE-3 molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013409.4|UniProtKB=F7ED49 F7ED49 PTHR24377:SF980 IP01015P-RELATED ZINC FINGER PROTEIN 420 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019505.3|UniProtKB=A0A5F8H496 A0A5F8H496 SLC38A9 PTHR22950:SF244 AMINO ACID TRANSPORTER NEUTRAL AMINO ACID TRANSPORTER 9 amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;L-amino acid transmembrane transporter activity#GO:0015179 amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;vacuole#GO:0005773;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774 secondary carrier transporter#PC00258;amino acid transporter#PC00046 MONDO|Ensembl=ENSMODG00000011907.5|UniProtKB=F7EGQ0 F7EGQ0 KAZALD1 PTHR14186:SF21 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED KAZAL-TYPE SERINE PROTEASE INHIBITOR DOMAIN-CONTAINING PROTEIN 1 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 interstitial matrix#GO:0005614;cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000007273.4|UniProtKB=A0A5F8G6P6 A0A5F8G6P6 CYP2R1 PTHR24300:SF48 CYTOCHROME P450 508A4-RELATED VITAMIN D 25-HYDROXYLASE tetrapyrrole binding#GO:0046906;binding#GO:0005488;steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;steroid metabolic process#GO:0008202;response to stimulus#GO:0050896;response to chemical#GO:0042221;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;vitamin D metabolic process#GO:0042359 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000015188.4|UniProtKB=F7BW03 F7BW03 PTHR21707:SF42 FLAGELLUM-ASSOCIATED COILED-COIL DOMAIN-CONTAINING PROTEIN 1 FLAGELLUM-ASSOCIATED COILED-COIL DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000018314.4|UniProtKB=F6PUG6 F6PUG6 CFAP206 PTHR21442:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206 microtubule-based process#GO:0007017;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;sperm motility#GO:0097722;regulation of biological process#GO:0050789;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell differentiation#GO:0030154;regulation of microtubule-based movement#GO:0060632;cell projection organization#GO:0030030;developmental process#GO:0032502;spermatogenesis#GO:0007283;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;male gamete generation#GO:0048232;regulation of reproductive process#GO:2000241;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;cell motility#GO:0048870 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930 MONDO|Ensembl=ENSMODG00000044399.1|UniProtKB=A0A5F8H6V1 A0A5F8H6V1 GNG14 PTHR13809:SF14 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494 heterotrimeric G-protein#PC00117 Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Wnt signaling pathway#P00057>Ggamma#P01465;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Nicotine pharmacodynamics pathway#P06587>GNG#P06590;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Enkephalin release#P05913>G-Protein (s)#P05977;Enkephalin release#P05913>G-Protein (i)#P05974 MONDO|Ensembl=ENSMODG00000050011.1|UniProtKB=A0A5F8G7L8 A0A5F8G7L8 PTHR13087:SF0 NF-KAPPA B ACTIVATING PROTEIN NFKB ACTIVATING PROTEIN LIKE regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000015963.5|UniProtKB=F6PG86 F6PG86 KIF1A PTHR24115:SF361 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF1A isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 cytosolic transport#GO:0016482;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;retrograde axonal transport#GO:0008090;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;axonal transport#GO:0098930;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;axo-dendritic transport#GO:0008088;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;vesicle-mediated transport#GO:0016192;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;microtubule-based process#GO:0007017;vesicle cytoskeletal trafficking#GO:0099518;transport along microtubule#GO:0010970;establishment of localization#GO:0051234 dendritic tree#GO:0097447;intracellular organelle#GO:0043229;axon#GO:0030424;dendrite#GO:0030425;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000048601.1|UniProtKB=A0A5F8G8D8 A0A5F8G8D8 GRAP PTHR46037:SF2 PROTEIN ENHANCER OF SEVENLESS 2B GRB2-RELATED ADAPTER PROTEIN growth factor receptor binding#GO:0070851;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cell communication#GO:0007154;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;COP9 signalosome#GO:0008180;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;nuclear protein-containing complex#GO:0140513 Angiogenesis#P00005>Grb2#P00252;EGF receptor signaling pathway#P00018>Grb2#P00550;B cell activation#P00010>Grb2#P00372;FGF signaling pathway#P00021>Grb2#P00631;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Grb#P00848;Angiogenesis#P00005>Grb2#P00234;Integrin signalling pathway#P00034>Grb2#P00910;PDGF signaling pathway#P00047>Grb2#P01148 MONDO|Ensembl=ENSMODG00000042284.1|UniProtKB=A0A5F8GTF4 A0A5F8GTF4 FGF18 PTHR11486:SF4 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 18 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of cell motility#GO:2000145;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;nervous system development#GO:0007399;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154 extracellular region#GO:0005576;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000046156.1|UniProtKB=A0A5F8HK80 A0A5F8HK80 S100A10 PTHR11639:SF74 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A10 calcium ion binding#GO:0005509;transmembrane transporter binding#GO:0044325;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000019457.4|UniProtKB=F6RWS2 F6RWS2 ASXL1 PTHR13578:SF19 ADDITIONAL SEX COMBS LIKE PROTEIN ASXL POLYCOMB GROUP PROTEIN ASXL1 binding#GO:0005488;signaling receptor binding#GO:0005102;chromatin binding#GO:0003682;protein binding#GO:0005515 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;developmental process#GO:0032502;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000042143.1|UniProtKB=A0A5F8H755 A0A5F8H755 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016676.4|UniProtKB=F7E6J3 F7E6J3 ARHGEF11 PTHR45872:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 11 signaling receptor binding#GO:0005102;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;G protein-coupled receptor binding#GO:0001664;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000050233.1|UniProtKB=A0A5F8GXB5 A0A5F8GXB5 LOC100020852 PTHR48018:SF170 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5D3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019094.4|UniProtKB=A0A5F8GRM5 A0A5F8GRM5 MSH4 PTHR11361:SF21 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER MUTS PROTEIN HOMOLOG 4 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;reproductive process#GO:0022414;homologous recombination#GO:0035825;cell cycle process#GO:0022402;reciprocal homologous recombination#GO:0140527;meiosis I#GO:0007127;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle#GO:0007049;organelle fission#GO:0048285;reciprocal meiotic recombination#GO:0007131;sexual reproduction#GO:0019953;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000000364.4|UniProtKB=A0A5F8H7Q3 A0A5F8H7Q3 TNNT2 PTHR11521:SF5 TROPONIN T TROPONIN T, CARDIAC MUSCLE cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;heart process#GO:0003015;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;striated muscle contraction#GO:0006941;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cardiac muscle contraction#GO:0060048;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system process#GO:0003013;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;muscle contraction#GO:0006936;developmental process#GO:0032502;system process#GO:0003008;heart contraction#GO:0060047;cellular developmental process#GO:0048869 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;contractile muscle fiber#GO:0043292;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;sarcomere#GO:0030017;membraneless organelle#GO:0043228 actin binding motor protein#PC00040 MONDO|Ensembl=ENSMODG00000027979.2|UniProtKB=K7E0Y0 K7E0Y0 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED RETROVIRAL ENVELOPE PROTEIN GP41-LIKE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000018806.4|UniProtKB=A0A5F8H7V7 A0A5F8H7V7 FBXO9 PTHR12874:SF29 F-BOX ONLY PROTEIN 48-RELATED F-BOX ONLY PROTEIN 9 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000013517.4|UniProtKB=F7D722 F7D722 CPNE5 PTHR10857:SF51 COPINE COPINE-5 phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289 response to chemical#GO:0042221;response to calcium ion#GO:0051592;response to stimulus#GO:0050896;cellular response to chemical stimulus#GO:0070887;response to metal ion#GO:0010038;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000003504.3|UniProtKB=F7C8L6 F7C8L6 CDK10 PTHR24056:SF508 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 10 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 mitotic cell cycle phase transition#GO:0044772;G2/M transition of mitotic cell cycle#GO:0000086;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;regulation of cell cycle#GO:0051726;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;mitotic cell cycle process#GO:1903047;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cell cycle G2/M phase transition#GO:1902749;cellular process#GO:0009987;cell cycle G2/M phase transition#GO:0044839 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000047404.1|UniProtKB=A0A5F8H9J3 A0A5F8H9J3 PTHR35444:SF1 RIKEN CDNA 1700001C19 GENE CILIARY MICROTUBULE INNER PROTEIN 3 MONDO|Ensembl=ENSMODG00000013733.4|UniProtKB=F6XQH8 F6XQH8 HIPK2 PTHR24058:SF137 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 2 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000017715.4|UniProtKB=F7FHG8 F7FHG8 PPM1F PTHR13832:SF233 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1F hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 regulation of actin filament bundle assembly#GO:0032231;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;positive regulation of cellular component organization#GO:0051130;cell communication#GO:0007154;positive regulation of organelle organization#GO:0010638;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;positive regulation of actin filament bundle assembly#GO:0032233 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000005060.4|UniProtKB=F7ASW7 F7ASW7 SLC7A3 PTHR43243:SF20 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 transport#GO:0006810;amino acid transport#GO:0006865;localization#GO:0051179;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;amino acid transporter#PC00046 MONDO|Ensembl=ENSMODG00000047263.1|UniProtKB=F6Z5G1 F6Z5G1 LOC100016553 PTHR48018:SF168 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009385.4|UniProtKB=A0A5F8GZ87 A0A5F8GZ87 RAB11FIP2 PTHR15746:SF20 RAB11-RELATED RAB11 FAMILY-INTERACTING PROTEIN 2 regulated exocytosis#GO:0045055;transport#GO:0006810;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;secretion by cell#GO:0032940;exocytosis#GO:0006887;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000043712.1|UniProtKB=K7E5F9 K7E5F9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000017090.3|UniProtKB=F6V419 F6V419 SERINC2 PTHR10383:SF22 SERINE INCORPORATOR SERINE INCORPORATOR 2 membrane#GO:0016020;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000018570.4|UniProtKB=A0A5F8GJ56 A0A5F8GJ56 ILK PTHR44329:SF57 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED SCAFFOLD PROTEIN ILK protein-macromolecule adaptor activity#GO:0030674;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;molecular adaptor activity#GO:0060090;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;integrin-mediated signaling pathway#GO:0007229;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;substrate adhesion-dependent cell spreading#GO:0034446;cellular developmental process#GO:0048869;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007 focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Integrin signalling pathway#P00034>ILK#P00935 MONDO|Ensembl=ENSMODG00000016706.3|UniProtKB=F7D1W5 F7D1W5 PTHR21603:SF16 ANTIGEN KI-67-LIKE PROTEIN CELL DIVISION CYCLE-ASSOCIATED PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;molecular condensate scaffold activity#GO:0140693 regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;regulation of mitotic nuclear division#GO:0007088;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;reproductive process#GO:0022414;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953 nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000024044.2|UniProtKB=F6YNS4 F6YNS4 TSKU PTHR45617:SF14 LEUCINE RICH REPEAT FAMILY PROTEIN TSUKUSHI scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000038008.1|UniProtKB=K7E1U0 K7E1U0 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000045549.1|UniProtKB=A0A5F8G2R1 A0A5F8G2R1 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025650.3|UniProtKB=F6XE08 F6XE08 LOC100027544 PTHR10751:SF141 GUANYLATE BINDING PROTEIN GB1_RHD3-TYPE G DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 G-protein#PC00020;heterotrimeric G-protein#PC00117 MONDO|Ensembl=ENSMODG00000015701.4|UniProtKB=F7E0I4 F7E0I4 KCNN2 PTHR10153:SF43 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 2 calmodulin binding#GO:0005516;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;binding#GO:0005488;gated channel activity#GO:0022836;protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion-gated channel activity#GO:0022839;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;calcium-activated potassium channel activity#GO:0015269;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227 monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810;potassium ion transport#GO:0006813;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell junction#GO:0030054;postsynapse#GO:0098794;cell body#GO:0044297;dendritic spine#GO:0043197;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;neuronal cell body#GO:0043025;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000004863.3|UniProtKB=F6TNY2 F6TNY2 NGF PTHR11589:SF10 NERVE GROWTH FACTOR NGF -RELATED BETA-NERVE GROWTH FACTOR molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;negative regulation of cellular process#GO:0048523;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;multicellular organismal process#GO:0032501;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;neuron development#GO:0048666;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;response to endogenous stimulus#GO:0009719;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular response to nerve growth factor stimulus#GO:1990090;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;regulation of apoptotic process#GO:0042981;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;regulation of trans-synaptic signaling#GO:0099177;nervous system development#GO:0007399;negative regulation of neuron apoptotic process#GO:0043524;neuron projection development#GO:0031175;regulation of neuron apoptotic process#GO:0043523;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069 cell junction#GO:0030054;presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;extracellular region#GO:0005576;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202 neurotrophic factor#PC00163;growth factor#PC00112 MONDO|Ensembl=ENSMODG00000014137.4|UniProtKB=F6XKP5 F6XKP5 APPBP2 PTHR46575:SF1 AMYLOID PROTEIN-BINDING PROTEIN 2 AMYLOID PROTEIN-BINDING PROTEIN 2 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;Cul2-RING ubiquitin ligase complex#GO:0031462;transferase complex#GO:1990234;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000004790.4|UniProtKB=F6W509 F6W509 ARR3 PTHR11792:SF19 ARRESTIN ARRESTIN-C G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;regulation of biological process#GO:0050789;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;localization#GO:0051179;nervous system process#GO:0050877;regulation of signaling#GO:0023051;sensory perception#GO:0007600;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;receptor internalization#GO:0031623;receptor-mediated endocytosis#GO:0006898;system process#GO:0003008;import into cell#GO:0098657;establishment of localization#GO:0051234;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;transport#GO:0006810;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>beta-arrestin#P01456 MONDO|Ensembl=ENSMODG00000047753.1|UniProtKB=F6U150 F6U150 NACC1 PTHR46105:SF3 AGAP004733-PA NUCLEUS ACCUMBENS-ASSOCIATED PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000043010.1|UniProtKB=A0A5F8H546 A0A5F8H546 PTHR23226:SF430 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 1010-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018196.4|UniProtKB=F7B6W0 F7B6W0 PLBD1 PTHR12370:SF1 N-TERMINAL NUCLEOPHILE (NTN) HYDROLASE LYSOSOMAL LEUCINE AMINOPEPTIDASE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000008696.4|UniProtKB=F6PX77 F6PX77 FBXW12 PTHR44019:SF17 WD REPEAT-CONTAINING PROTEIN 55 F-BOX_WD REPEAT-CONTAINING PROTEIN 12 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000020279.3|UniProtKB=F7C0S7 F7C0S7 HMGCS1 PTHR43323:SF4 3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE HYDROXYMETHYLGLUTARYL-COA SYNTHASE, CYTOPLASMIC catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;acetyl-CoA metabolic process#GO:0006084;metabolic process#GO:0008152 Cholesterol biosynthesis#P00014>Hydroxymethyl glutaryl CoA synthase#P00498 MONDO|Ensembl=ENSMODG00000003804.4|UniProtKB=F7FYB4 F7FYB4 SMURF2 PTHR11254:SF300 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE SMURF2 protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 negative regulation of response to stimulus#GO:0048585;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968;regulation of BMP signaling pathway#GO:0030510;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;negative regulation of BMP signaling pathway#GO:0030514;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 TGF-beta signaling pathway#P00052>Smurfs#P01279;Ubiquitin proteasome pathway#P00060>E3#P01490 MONDO|Ensembl=ENSMODG00000014912.3|UniProtKB=A0A5F8HGQ8 A0A5F8HGQ8 FKBPL PTHR46512:SF10 PEPTIDYLPROLYL ISOMERASE FK506-BINDING PROTEIN-LIKE chaperone#PC00072 MONDO|Ensembl=ENSMODG00000015788.4|UniProtKB=A0A5F8GCU0 A0A5F8GCU0 OTOF PTHR12546:SF32 FER-1-LIKE OTOFERLIN calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;protein-containing complex binding#GO:0044877;metal ion binding#GO:0046872 signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;response to mechanical stimulus#GO:0009612;synaptic vesicle recycling#GO:0036465;multicellular organismal process#GO:0032501;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;response to external stimulus#GO:0009605;system process#GO:0003008;response to abiotic stimulus#GO:0009628;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;response to stimulus#GO:0050896;sensory perception of sound#GO:0007605;export from cell#GO:0140352;signaling#GO:0023052;nervous system process#GO:0050877;plasma membrane organization#GO:0007009;cellular localization#GO:0051641;secretion by cell#GO:0032940;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;neurotransmitter transport#GO:0006836;regulated exocytosis#GO:0045055;exocytic process#GO:0140029;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933 organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;presynapse#GO:0098793;cell junction#GO:0030054;presynaptic active zone#GO:0048786;bounding membrane of organelle#GO:0098588;synaptic membrane#GO:0097060;intracellular membrane-bounded organelle#GO:0043231;presynaptic active zone membrane#GO:0048787;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;organelle membrane#GO:0031090 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000023858.3|UniProtKB=F6X3H7 F6X3H7 LOC130459013 PTHR44427:SF1 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CELL ADHESION MOLECULE CEACAM1 protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000024332.2|UniProtKB=F7DG96 F7DG96 LOC100022915 PTHR26452:SF334 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000037138.1|UniProtKB=A0A5F8G3B7 A0A5F8G3B7 monDomV1R1201 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000050475.1|UniProtKB=A0A5F8G2I3 A0A5F8G2I3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000023264.3|UniProtKB=F7GGK4 F7GGK4 CABLES2 PTHR22896:SF3 CDK5 AND ABL1 ENZYME SUBSTRATE 1 CDK5 AND ABL1 ENZYME SUBSTRATE 2 MONDO|Ensembl=ENSMODG00000021001.4|UniProtKB=A0A5F8G6Q4 A0A5F8G6Q4 APP PTHR23103:SF7 ALZHEIMER'S DISEASE BETA-AMYLOID RELATED AMYLOID-BETA PRECURSOR PROTEIN protein binding#GO:0005515;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor regulator activity#GO:0030545 anatomical structure development#GO:0048856;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;central nervous system development#GO:0007417;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987 cell surface#GO:0009986;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;Golgi apparatus#GO:0005794;membrane microdomain#GO:0098857;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane raft#GO:0045121;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 protease inhibitor#PC00191 Blood coagulation#P00011>PN2#P00429;Alzheimer disease-amyloid secretase pathway#P00003>C83#P00100;Alzheimer disease-amyloid secretase pathway#P00003>APPalpha#P00097;Alzheimer disease-amyloid secretase pathway#P00003>APP#P00085;Alzheimer disease-amyloid secretase pathway#P00003>p3#P00086;Alzheimer disease-amyloid secretase pathway#P00003>C99#P00106;Alzheimer disease-presenilin pathway#P00004>APP#P00127;Alzheimer disease-presenilin pathway#P00004>C99#P00111;Alzheimer disease-presenilin pathway#P00004>APPbeta#P00151;Alzheimer disease-amyloid secretase pathway#P00003>AICD#P00080;Alzheimer disease-presenilin pathway#P00004>AICD#P00166;Alzheimer disease-presenilin pathway#P00004>Abeta#P00136;Alzheimer disease-amyloid secretase pathway#P00003>Abeta#P00096;Alzheimer disease-amyloid secretase pathway#P00003>APPbeta#P00104 MONDO|Ensembl=ENSMODG00000018576.4|UniProtKB=F7FRC3 F7FRC3 FAIM PTHR13088:SF3 FAS APOPTOTIC INHIBITORY MOLECULE FAIM FAS APOPTOTIC INHIBITORY MOLECULE 1 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of programmed cell death#GO:0043067;negative regulation of cell communication#GO:0010648;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;negative regulation of programmed cell death#GO:0043069;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 MONDO|Ensembl=ENSMODG00000004204.3|UniProtKB=F6XRB9 F6XRB9 CEP20 PTHR15431:SF21 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN CENTROSOMAL PROTEIN 20 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centrosome#GO:0005813;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000011549.4|UniProtKB=F6QWQ3 F6QWQ3 PTHR14611:SF1 TECTONIC FAMILY MEMBER TECTONIC-1 cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;cell projection assembly#GO:0030031;cellular process#GO:0009987;localization#GO:0051179;cilium organization#GO:0044782;organelle assembly#GO:0070925;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;protein localization to cilium#GO:0061512;cilium assembly#GO:0060271;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;cilium#GO:0005929;ciliary transition zone#GO:0035869;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000006270.4|UniProtKB=A0A5F8H0F3 A0A5F8H0F3 PTHR11306:SF68 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 2 binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934;alcohol binding#GO:0043178;steroid binding#GO:0005496;cholesterol binding#GO:0015485;lipid binding#GO:0008289 intracellular transport#GO:0046907;lipid localization#GO:0010876;transport#GO:0006810;establishment of localization#GO:0051234;sterol transport#GO:0015918;cellular localization#GO:0051641;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;cellular process#GO:0009987;cholesterol efflux#GO:0033344;establishment of localization in cell#GO:0051649;lipid transport#GO:0006869;intracellular sterol transport#GO:0032366 MONDO|Ensembl=ENSMODG00000010372.4|UniProtKB=F6R3Y1 F6R3Y1 SCARF1 PTHR24043:SF0 SCAVENGER RECEPTOR CLASS F SCAVENGER RECEPTOR CLASS F MEMBER 1 cargo receptor activity#GO:0038024;protein-containing complex binding#GO:0044877;binding#GO:0005488;lipoprotein particle binding#GO:0071813;protein-lipid complex binding#GO:0071814;low-density lipoprotein particle binding#GO:0030169 plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental maturation#GO:0021700;positive regulation of cellular process#GO:0048522;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cell maturation#GO:0048469;regulation of plasma membrane bounded cell projection organization#GO:0120035;developmental process#GO:0032502;regulation of cell projection organization#GO:0031344;regulation of cellular process#GO:0050794;anatomical structure maturation#GO:0071695;system development#GO:0048731;anatomical structure development#GO:0048856;positive regulation of cell projection organization#GO:0031346;nervous system development#GO:0007399;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;dendrite development#GO:0016358;cell adhesion#GO:0007155;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;positive regulation of neuron projection development#GO:0010976 cellular anatomical structure#GO:0110165;membrane#GO:0016020 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000049316.1|UniProtKB=A0A5F8H9A4 A0A5F8H9A4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000002335.4|UniProtKB=F7GLY3 F7GLY3 PTHR33775:SF2 CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN-RELATED CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;muscle contraction#GO:0006936;heart contraction#GO:0060047;system process#GO:0003008;cardiac muscle cell contraction#GO:0086003;actin filament-based movement#GO:0030048;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;positive regulation of response to stimulus#GO:0048584;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;positive regulation of calcium-mediated signaling#GO:0050850;circulatory system process#GO:0003013;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;striated muscle contraction#GO:0006941;regulation of calcium-mediated signaling#GO:0050848;regulation of cellular process#GO:0050794;actin-mediated cell contraction#GO:0070252;positive regulation of cell communication#GO:0010647;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of calcineurin-NFAT signaling cascade#GO:0070884;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;heart process#GO:0003015;regulation of biological process#GO:0050789;muscle system process#GO:0003012 Z disc#GO:0030018;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;I band#GO:0031674;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 MONDO|Ensembl=ENSMODG00000024660.1|UniProtKB=F7CA37 F7CA37 LOC100010256 PTHR26453:SF627 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016637.3|UniProtKB=F7GH03 F7GH03 LOC100016060 PTHR11442:SF95 HEMOGLOBIN FAMILY MEMBER GLOBIN DOMAIN-CONTAINING PROTEIN heme binding#GO:0020037;molecular carrier activity#GO:0140104;binding#GO:0005488;tetrapyrrole binding#GO:0046906 cellular process#GO:0009987;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;developmental process#GO:0032502;transport#GO:0006810;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;multicellular organismal-level homeostasis#GO:0048871;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;homeostatic process#GO:0042592;cell development#GO:0048468;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;localization#GO:0051179;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 globin#PC00107;transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000006426.4|UniProtKB=F7EZH8 F7EZH8 PRSS57 PTHR24271:SF55 KALLIKREIN-RELATED SERINE PROTEASE 57 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000027509.2|UniProtKB=K7E0J8 K7E0J8 TMEM95 PTHR38808:SF1 TRANSMEMBRANE PROTEIN 95 SPERM-EGG FUSION PROTEIN TMEM95 sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;cellular process#GO:0009987;fusion of sperm to egg plasma membrane involved in single fertilization#GO:0007342;single fertilization#GO:0007338;fertilization#GO:0009566;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;acrosomal membrane#GO:0002080;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;secretory granule membrane#GO:0030667;intracellular vesicle#GO:0097708 MONDO|Ensembl=ENSMODG00000006548.4|UniProtKB=H9H674 H9H674 PTHR24377:SF1028 IP01015P-RELATED ZINC FINGER PROTEIN 84 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000000393.3|UniProtKB=F6R7V5 F6R7V5 DBI PTHR23310:SF62 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING PROTEIN anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;lipid binding#GO:0008289;heterocyclic compound binding#GO:1901363 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000040658.1|UniProtKB=A0A5F8GGM8 A0A5F8GGM8 GET1 PTHR42650:SF1 TAIL-ANCHORED PROTEIN INSERTION RECEPTOR WRB GUIDED ENTRY OF TAIL-ANCHORED PROTEINS FACTOR 1 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000044287.1|UniProtKB=A0A5F8GVK5 A0A5F8GVK5 LOC103105101 PTHR23226:SF425 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 24 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000043310.1|UniProtKB=A0A5F8GF33 A0A5F8GF33 IDNK PTHR43442:SF3 GLUCONOKINASE-RELATED GLUCONOKINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;pentose-phosphate shunt#GO:0006098;oxoacid metabolic process#GO:0043436;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117 kinase#PC00137 MONDO|Ensembl=ENSMODG00000001890.4|UniProtKB=F6WGJ1 F6WGJ1 LOC100023663 PTHR24291:SF39 CYTOCHROME P450 FAMILY 4 TAUROCHENODEOXYCHOLIC 6 ALPHA-HYDROXYLASE oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000014000.4|UniProtKB=F6VQY0 F6VQY0 PTHR19971:SF24 SIGNAL-REGULATORY PROTEIN BETA IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008925.3|UniProtKB=F7GL60 F7GL60 PTHR26453:SF223 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2W3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008527.4|UniProtKB=F7DBW2 F7DBW2 PTHR24377:SF710 IP01015P-RELATED ZINC FINGER PROTEIN 181-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019899.5|UniProtKB=A0A5F8GII6 A0A5F8GII6 CSTPP1 PTHR34252:SF1 UPF0705 PROTEIN C11ORF49 CENTRIOLAR SATELLITE-ASSOCIATED TUBULIN POLYGLUTAMYLASE COMPLEX REGULATOR 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010 MONDO|Ensembl=ENSMODG00000006588.2|UniProtKB=F7AKX0 F7AKX0 CTDNEP1 PTHR12210:SF70 DULLARD PROTEIN PHOSPHATASE CTD NUCLEAR ENVELOPE PHOSPHATASE 1 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000011994.3|UniProtKB=F7B980 F7B980 SEC23A PTHR11141:SF7 PROTEIN TRANSPORT PROTEIN SEC23 PROTEIN TRANSPORT PROTEIN SEC23A enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cellular component organization#GO:0016043;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507;cytoplasm#GO:0005737;vesicle coat#GO:0030120;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506 membrane traffic protein#PC00150;vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000019272.4|UniProtKB=F6SI13 F6SI13 PTHR23050:SF218 CALCIUM BINDING PROTEIN CENTRIN-1 metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;centriole replication#GO:0007099;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000004110.4|UniProtKB=F6VE42 F6VE42 NELFA PTHR13328:SF7 NEGATIVE ELONGATION FACTOR A NELF-A NEGATIVE ELONGATION FACTOR A negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;nucleoplasm#GO:0005654;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000001912.4|UniProtKB=F6W1D0 F6W1D0 MYO5C PTHR13140:SF313 MYOSIN UNCONVENTIONAL MYOSIN-VC microfilament motor activity#GO:0000146;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000010568.4|UniProtKB=F6YQS9 F6YQS9 PTHR21228:SF59 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 4 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;regulation of RNA stability#GO:0043487;mitochondrial RNA metabolic process#GO:0000959;regulation of RNA metabolic process#GO:0051252;mitochondrial gene expression#GO:0140053;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000002265.3|UniProtKB=F7CW54 F7CW54 TAT PTHR45744:SF46 TYROSINE AMINOTRANSFERASE TYROSINE AMINOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 transaminase#PC00216 Tyrosine biosynthesis#P02784>Aromatic amino acid aminotransferase#P03213 MONDO|Ensembl=ENSMODG00000037931.1|UniProtKB=A0A5F8HBA5 A0A5F8HBA5 PTHR24377:SF710 IP01015P-RELATED ZINC FINGER PROTEIN 181-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015173.3|UniProtKB=F6XFE0 F6XFE0 PTHR19375:SF581 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111 biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein refolding#GO:0042026;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Hsp70 family chaperone#PC00027;chaperone#PC00072 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 MONDO|Ensembl=ENSMODG00000003606.3|UniProtKB=F7C6K7 F7C6K7 TNFAIP6 PTHR46908:SF10 CUBILIN-LIKE PROTEIN TUMOR NECROSIS FACTOR-INDUCIBLE GENE 6 PROTEIN negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of response to stimulus#GO:0048583;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;regulation of response to stress#GO:0080134 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000017453.4|UniProtKB=A0A5F8GJH5 A0A5F8GJH5 MTFR2 PTHR14215:SF2 PROTEIN OF UNKNOWN FUNCTION DUF729 MITOCHONDRIAL FISSION REGULATOR 2 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;mitochondrial fission#GO:0000266;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000025779.2|UniProtKB=F7FSW2 F7FSW2 LOC100010137 PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 reductase#PC00198 MONDO|Ensembl=ENSMODG00000018352.4|UniProtKB=F6PQI9 F6PQI9 PTHR16317:SF1 INTEGRIN ALPHA REPEAT DOMAIN-CONTAINING KICSTOR COMPLEX PROTEIN ITFG2 regulation of TORC1 signaling#GO:1903432;cellular response to nutrient levels#GO:0031669;negative regulation of TORC1 signaling#GO:1904262;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;negative regulation of response to stimulus#GO:0048585;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;response to nutrient levels#GO:0031667;response to stress#GO:0006950;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;negative regulation of biological process#GO:0048519 protein-containing complex#GO:0032991 integrin#PC00126 MONDO|Ensembl=ENSMODG00000005391.4|UniProtKB=A0A5F8H636 A0A5F8H636 NCAPG2 PTHR16199:SF4 CONDENSIN-2 COMPLEX SUBUNIT G2 CONDENSIN-2 COMPLEX SUBUNIT G2 mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;organelle fission#GO:0048285;nuclear division#GO:0000280;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059 condensin complex#GO:0000796;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000018322.4|UniProtKB=F6PTH3 F6PTH3 SLC49A4 PTHR10924:SF27 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED SOLUTE CARRIER FAMILY 49 MEMBER 4 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000023558.3|UniProtKB=F6Z0S8 F6Z0S8 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000046354.1|UniProtKB=A0A5F8GHJ5 A0A5F8GHJ5 BNIPL PTHR12112:SF21 BNIP - RELATED BCL-2_ADENOVIRUS E1B 19 KDA-INTERACTING PROTEIN 2-LIKE PROTEIN cellular process#GO:0009987;cell death#GO:0008219;apoptotic process#GO:0006915;programmed cell death#GO:0012501 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000017966.4|UniProtKB=F7BVH7 F7BVH7 ZBTB24 PTHR24399:SF39 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 24 sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000021446.4|UniProtKB=F7BT45 F7BT45 TWSG1 PTHR12312:SF17 TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED TWISTED GASTRULATION PROTEIN HOMOLOG 1 regulation of BMP signaling pathway#GO:0030510;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000005950.3|UniProtKB=F6WFW6 F6WFW6 TPPP3 PTHR12932:SF16 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN FAMILY MEMBER 3 protein binding#GO:0005515;binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;positive regulation of protein polymerization#GO:0032273;cellular component assembly#GO:0022607;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;protein polymerization#GO:0051258;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;positive regulation of cellular component organization#GO:0051130;microtubule bundle formation#GO:0001578 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000045664.1|UniProtKB=F6S9M3 F6S9M3 LOC100020628 PTHR48002:SF45 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000029467.2|UniProtKB=K7E403 K7E403 LOC103099360 PTHR13857:SF42 MRNA EDITING ENZYME DNA DC-DU-EDITING ENZYME APOBEC-3A-LIKE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824;RNA binding#GO:0003723;hydrolase activity#GO:0016787;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular process#GO:0009987;primary metabolic process#GO:0044238;cytidine to uridine editing#GO:0016554;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;RNA modification#GO:0009451;metabolic process#GO:0008152;base conversion or substitution editing#GO:0016553;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000007478.4|UniProtKB=A0A5F8GYX2 A0A5F8GYX2 TCP1 PTHR11353:SF84 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ALPHA primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031 chaperonin#PC00073 MONDO|Ensembl=ENSMODG00000014805.4|UniProtKB=A0A5F8HE12 A0A5F8HE12 RGCC PTHR32193:SF3 REGULATOR OF CELL CYCLE RGCC REGULATOR OF CELL CYCLE RGCC kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887 regulation of cell cycle G1/S phase transition#GO:1902806;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of cell cycle phase transition#GO:1901987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of immune response#GO:0050776;response to transforming growth factor beta#GO:0071559;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;positive regulation of mitotic cell cycle#GO:0045931;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;immune system process#GO:0002376;regulation of cell cycle process#GO:0010564;intracellular signaling cassette#GO:0141124;positive regulation of cell cycle#GO:0045787;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell cycle G1/S phase transition#GO:1902808 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000010843.3|UniProtKB=A0A5F8HKB9 A0A5F8HKB9 PTHR15711:SF17 RAP GTPASE-ACTIVATING PROTEIN RAP1 GTPASE-ACTIVATING PROTEIN 2 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;axon#GO:0030424 G-protein modulator#PC00022;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000006773.2|UniProtKB=F7BTQ8 F7BTQ8 PTHR11927:SF9 GALACTOSIDE 2-L-FUCOSYLTRANSFERASE L-FUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000012264.4|UniProtKB=F6YGG5 F6YGG5 ZCCHC8 PTHR13316:SF0 ZINC FINGER, CCHC DOMAIN CONTAINING 8 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 8 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000023127.2|UniProtKB=F6VVR7 F6VVR7 PRKRIP1 PTHR13507:SF0 PRKR-INTERACTING PROTEIN 1 PRKR-INTERACTING PROTEIN 1 molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;kinase inhibitor activity#GO:0019210;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;nucleic acid binding#GO:0003676;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 MONDO|Ensembl=ENSMODG00000020448.5|UniProtKB=F7AQF9 F7AQF9 ONECUT2 PTHR14057:SF10 TRANSCRIPTION FACTOR ONECUT ONE CUT DOMAIN FAMILY MEMBER 2 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000019111.4|UniProtKB=F7F993 F7F993 HEATR6 PTHR13366:SF0 MALARIA ANTIGEN-RELATED HEAT REPEAT-CONTAINING PROTEIN 6 MONDO|Ensembl=ENSMODG00000004181.4|UniProtKB=F6QNP3 F6QNP3 TRPS1 PTHR47034:SF1 ZINC FINGER TRANSCRIPTION FACTOR TRPS1 ZINC FINGER TRANSCRIPTION FACTOR TRPS1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000024437.2|UniProtKB=F7DK42 F7DK42 PTHR45961:SF5 IP21249P DUAL SPECIFICITY PROTEIN PHOSPHATASE 14 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000011791.4|UniProtKB=F7CBU9 F7CBU9 PLA2G4A PTHR10728:SF13 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 phospholipid binding#GO:0005543;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;cation binding#GO:0043169;ion binding#GO:0043167;lipase activity#GO:0016298;small molecule binding#GO:0036094;carboxylic ester hydrolase activity#GO:0052689;A2-type glycerophospholipase activity#GO:0004623;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;metal ion binding#GO:0046872;lipid binding#GO:0008289;binding#GO:0005488;calcium ion binding#GO:0005509 phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;cellular process#GO:0009987;lipid catabolic process#GO:0016042;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475;lipid metabolic process#GO:0006629;glycerolipid catabolic process#GO:0046503;metabolic process#GO:0008152 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 phospholipase#PC00186 Oxidative stress response#P00046>cPLA2#P01134;Endothelin signaling pathway#P00019>cPLA2#P00583;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLA2#P00855;VEGF signaling pathway#P00056>cPLA2#P01409;Angiogenesis#P00005>PLA2#P00227;Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;CCKR signaling map#P06959>PLA2#P07086;Angiogenesis#P00005>cPLA2#P00251 MONDO|Ensembl=ENSMODG00000015199.4|UniProtKB=F7BA30 F7BA30 ANKLE2 PTHR12349:SF4 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902;protein phosphatase binding#GO:0019903;protein binding#GO:0005515 organelle fission#GO:0048285;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;membrane assembly#GO:0071709;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;mitotic cell cycle process#GO:1903047;nuclear envelope organization#GO:0006998;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000025676.3|UniProtKB=A0A5F8H537 A0A5F8H537 LOC100022053 PTHR13019:SF9 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 HOMOLOG B transport#GO:0006810;intracellular protein localization#GO:0008104;secretion by cell#GO:0032940;protein transport#GO:0015031;establishment of protein localization to extracellular region#GO:0035592;localization#GO:0051179;protein secretion#GO:0009306;establishment of localization#GO:0051234;secretion#GO:0046903;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein localization to extracellular region#GO:0071692;macromolecule localization#GO:0033036;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 MONDO|Ensembl=ENSMODG00000044533.1|UniProtKB=A0A5F8H312 A0A5F8H312 LOC100618673 PTHR48002:SF67 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007189.4|UniProtKB=F6X9S3 F6X9S3 GATAD2A PTHR13455:SF3 TRANSCRIPTIONAL REPRESSOR P66-RELATED TRANSCRIPTIONAL REPRESSOR P66-ALPHA DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;chromatin#GO:0000785 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000004399.2|UniProtKB=F6SVK5 F6SVK5 LOC100025087 PTHR22811:SF3 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 11 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;Golgi organization#GO:0007030;cellular component organization#GO:0016043;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192 endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000023939.2|UniProtKB=F7FA49 F7FA49 CERS1 PTHR12560:SF58 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;ceramide metabolic process#GO:0006672 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000015673.4|UniProtKB=F7EHU0 F7EHU0 GFM1 PTHR43636:SF2 ELONGATION FACTOR G, MITOCHONDRIAL ELONGATION FACTOR G, MITOCHONDRIAL translation factor activity#GO:0180051;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000017849.4|UniProtKB=F6Z7W4 F6Z7W4 NT5DC1 PTHR12103:SF38 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 1 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 hydrolase#PC00121;nucleotide phosphatase#PC00173;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000018248.4|UniProtKB=F6PG06 F6PG06 YBX3 PTHR11544:SF14 COLD SHOCK DOMAIN CONTAINING PROTEINS Y-BOX-BINDING PROTEIN 3 nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Gonadotropin-releasing hormone receptor pathway#P06664>Csda#P06797 MONDO|Ensembl=ENSMODG00000040765.1|UniProtKB=A0A5F8H291 A0A5F8H291 PTHR11562:SF51 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A2 transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;response to stimulus#GO:0050896;metal ion transport#GO:0030001;establishment of localization#GO:0051234;response to metal ion#GO:0010038;transport#GO:0006810;response to chemical#GO:0042221;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000028668.2|UniProtKB=K7E5B7 K7E5B7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000014269.4|UniProtKB=A0A5F8G5Z9 A0A5F8G5Z9 TAFA2 PTHR31770:SF1 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER CHEMOKINE-LIKE PROTEIN TAFA-2 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074;cytokine#PC00083 MONDO|Ensembl=ENSMODG00000041521.1|UniProtKB=A0A5F8GP46 A0A5F8GP46 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007048.2|UniProtKB=F6UFE3 F6UFE3 LOC100022735 PTHR26453:SF139 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000036916.1|UniProtKB=A0A5F8H335 A0A5F8H335 SLC22A8 PTHR24064:SF681 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000016233.4|UniProtKB=A0A5F8GKY1 A0A5F8GKY1 EYA2 PTHR10190:SF7 EYES ABSENT PROTEIN PHOSPHATASE EYA2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;positive regulation of DNA metabolic process#GO:0051054;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;positive regulation of DNA repair#GO:0045739;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000011648.2|UniProtKB=A0A5F8GYX4 A0A5F8GYX4 TWF2 PTHR13759:SF9 TWINFILIN TWINFILIN-2 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin monomer binding#GO:0003785;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488 regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;actin filament depolymerization#GO:0030042;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;regulation of anatomical structure size#GO:0090066;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;cellular component disassembly#GO:0022411;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;positive regulation of neuron projection development#GO:0010976;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;protein depolymerization#GO:0051261;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of actin filament depolymerization#GO:0030834;protein-containing complex disassembly#GO:0032984;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;regulation of cell projection assembly#GO:0060491;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;actin filament-based process#GO:0030029;positive regulation of cell projection organization#GO:0031346;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;actin filament#GO:0005884;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000010289.4|UniProtKB=A0A5F8GAR0 A0A5F8GAR0 TECTB PTHR14002:SF13 ENDOGLIN/TGF-BETA RECEPTOR TYPE III BETA-TECTORIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007239.4|UniProtKB=F6WBT1 F6WBT1 LOC100030898 PTHR11956:SF5 ARGINYL-TRNA SYNTHETASE ARGININE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000002504.3|UniProtKB=F7B9P3 F7B9P3 EIF2B3 PTHR45989:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA TRANSLATION INITIATION FACTOR EIF2B SUBUNIT GAMMA guanyl-nucleotide exchange factor activity#GO:0005085;translation factor activity#GO:0180051;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;translation initiation factor activity#GO:0003743;molecular function regulator activity#GO:0098772 cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412 guanyl-nucleotide exchange factor complex#GO:0032045;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000005785.2|UniProtKB=A0A5F8GQC0 A0A5F8GQC0 PTHR10744:SF9 40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US17 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000009261.3|UniProtKB=F7DB56 F7DB56 LOC100029431 PTHR15360:SF2 PLATELET-DERIVED GROWTH FACTOR RECEPTOR LIKE PLATELET-DERIVED GROWTH FACTOR RECEPTOR-LIKE PROTEIN tyrosine protein kinase receptor#PC00233 MONDO|Ensembl=ENSMODG00000000618.4|UniProtKB=A0A5F8GMA9 A0A5F8GMA9 TUT4 PTHR12271:SF49 POLY A POLYMERASE CID PAP -RELATED TERMINAL URIDYLYLTRANSFERASE 4 transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;positive regulation of macromolecule metabolic process#GO:0010604;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014 nucleotidyltransferase#PC00174 MONDO|Ensembl=ENSMODG00000046378.1|UniProtKB=A0A5F8GZF6 A0A5F8GZF6 LOC100617898 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000000986.3|UniProtKB=F7ES37 F7ES37 PHAX PTHR13135:SF0 CYTOSOLIC RESINIFERATOXIN BINDING PROTEIN RBP-26 PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000015065.5|UniProtKB=F7FHJ7 F7FHJ7 PTHR15715:SF26 CENTROSOMAL PROTEIN OF 170 KDA COILED-COIL DOMAIN-CONTAINING PROTEIN 136 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;regulation of cell communication#GO:0010646;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;sexual reproduction#GO:0019953;spermatid development#GO:0007286;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;negative regulation of response to stimulus#GO:0048585;male gamete generation#GO:0048232;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;spermatogenesis#GO:0007283;regulation of response to stimulus#GO:0048583;cellular developmental process#GO:0048869;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell development#GO:0048468;fertilization#GO:0009566;cellular process involved in reproduction in multicellular organism#GO:0022412;regulation of hippo signaling#GO:0035330;negative regulation of signaling#GO:0023057;spermatid differentiation#GO:0048515;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;acrosome assembly#GO:0001675;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of hippo signaling#GO:0035331;negative regulation of cell communication#GO:0010648;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;single fertilization#GO:0007338;cellular process#GO:0009987;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;negative regulation of signal transduction#GO:0009968;cellular anatomical entity morphogenesis#GO:0032989;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;anatomical structure formation involved in morphogenesis#GO:0048646 intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;acrosomal membrane#GO:0002080;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017074.4|UniProtKB=F6VKY5 F6VKY5 PTHR13084:SF4 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 1 regulation of biological process#GO:0050789;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of transport#GO:0051049 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000051259.1|UniProtKB=A0A5F8H3R4 A0A5F8H3R4 PTHR26450:SF422 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024113.3|UniProtKB=F6V618 F6V618 CDPF1 PTHR31849:SF1 CYSTEINE-RICH PDF MOTIF DOMAIN-CONTAINING PROTEIN 1 CYSTEINE-RICH DPF MOTIF DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000040564.1|UniProtKB=A0A5F8G9H1 A0A5F8G9H1 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000024326.1|UniProtKB=F7DGD1 F7DGD1 LOC100023114 PTHR48018:SF73 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8I2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040672.1|UniProtKB=A0A5F8GE81 A0A5F8GE81 LOC100028279 PTHR43128:SF10 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A CHAIN catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 generation of precursor metabolites and energy#GO:0006091;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;energy derivation by oxidation of organic compounds#GO:0015980;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid catabolic process#GO:0072329 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000008110.4|UniProtKB=F7G5I4 F7G5I4 PPIG PTHR11071:SF292 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE G intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000048321.1|UniProtKB=A0A5F8H2C2 A0A5F8H2C2 PTHR33064:SF42 POL PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000037958.1|UniProtKB=A0A5F8HFN4 A0A5F8HFN4 NXPH3 PTHR17103:SF14 NEUREXOPHILIN NEUREXOPHILIN-3 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 GABA-ergic synapse#GO:0098982;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000016122.3|UniProtKB=F7DSU1 F7DSU1 ACTRT3 PTHR11937:SF159 ACTIN ACTIN-RELATED PROTEIN T3 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 actin and actin related protein#PC00039 Alzheimer disease-presenilin pathway#P00004>actin#P00114;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944 MONDO|Ensembl=ENSMODG00000003805.3|UniProtKB=F6ZJ97 F6ZJ97 SKA1 PTHR28573:SF1 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1 SKA COMPLEX SUBUNIT 1 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 regulation of microtubule-based process#GO:0032886;chromosome segregation#GO:0007059;regulation of microtubule polymerization or depolymerization#GO:0031110;cell cycle#GO:0007049;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507 condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;spindle#GO:0005819;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;outer kinetochore#GO:0000940;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;supramolecular fiber#GO:0099512;spindle microtubule#GO:0005876;microtubule#GO:0005874;kinetochore#GO:0000776;chromosome#GO:0005694;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000011840.5|UniProtKB=A0A5F8GGG3 A0A5F8GGG3 FBXO33 PTHR20933:SF3 F-BOX ONLY PROTEIN 33 F-BOX ONLY PROTEIN 33 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of protein modification process#GO:0031399;regulation of protein ubiquitination#GO:0031396 MONDO|Ensembl=ENSMODG00000049268.1|UniProtKB=A0A5F8GDM0 A0A5F8GDM0 STARD5 PTHR46374:SF3 PROTEIN CBG07384 STAR-RELATED LIPID TRANSFER PROTEIN 5 molecular carrier activity#GO:0140104;sterol binding#GO:0032934;lipid carrier activity#GO:0005319;small molecule binding#GO:0036094;binding#GO:0005488;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;cholesterol binding#GO:0015485;transporter activity#GO:0005215;sterol transfer activity#GO:0120015;steroid binding#GO:0005496;cholesterol transfer activity#GO:0120020;alcohol binding#GO:0043178 localization#GO:0051179;sterol transport#GO:0015918;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;transport#GO:0006810;lipid transport#GO:0006869;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301 MONDO|Ensembl=ENSMODG00000006436.4|UniProtKB=F7EYW6 F7EYW6 SCN2A PTHR10037:SF278 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 2 SUBUNIT ALPHA monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;passive transmembrane transporter activity#GO:0022803;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated sodium channel activity#GO:0005248;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;transmembrane transport#GO:0055085;sensory perception#GO:0007600;nervous system process#GO:0050877;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;action potential#GO:0001508;sodium ion transport#GO:0006814;sensory perception of pain#GO:0019233;system process#GO:0003008;transmission of nerve impulse#GO:0019226;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987 cation channel complex#GO:0034703;transporter complex#GO:1990351;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;axon#GO:0030424;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000006959.4|UniProtKB=F6QVZ5 F6QVZ5 HOOK2 PTHR18947:SF37 HOOK PROTEINS PROTEIN HOOK HOMOLOG 2 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular component organization#GO:0016043;cytoplasmic microtubule organization#GO:0031122;supramolecular fiber organization#GO:0097435;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000020291.4|UniProtKB=F7BFY4 F7BFY4 C6 PTHR45742:SF4 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C6 humoral immune response#GO:0006959;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;positive regulation of immune response#GO:0050778;positive regulation of immune system process#GO:0002684;complement activation#GO:0006956;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;extracellular region#GO:0005576 complement component#PC00078 MONDO|Ensembl=ENSMODG00000010786.4|UniProtKB=F7CII5 F7CII5 PTHR12191:SF21 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP4 transition metal ion transmembrane transporter activity#GO:0046915;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;zinc ion transmembrane transporter activity#GO:0005385;bicarbonate transmembrane transporter activity#GO:0015106;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873 intracellular monoatomic ion homeostasis#GO:0006873;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000005255.5|UniProtKB=A0A5F8G6K2 A0A5F8G6K2 PAK3 PTHR48015:SF30 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE PAK 3 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;cellular response to starvation#GO:0009267;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell migration#GO:0016477;response to nutrient levels#GO:0031667;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cytoskeleton organization#GO:0051493;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of axonogenesis#GO:0050770;regulation of anatomical structure morphogenesis#GO:0022603;regulation of MAPK cascade#GO:0043408;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;response to stress#GO:0006950;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517;T cell activation#P00053>PAK#P01319;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;Angiogenesis#P00005>PAK#P00249;Ras Pathway#P04393>PAK#P04553 MONDO|Ensembl=ENSMODG00000007162.4|UniProtKB=F6RD67 F6RD67 MAU2 PTHR21394:SF0 MAU2 CHROMATID COHESION FACTOR HOMOLOG MAU2 CHROMATID COHESION FACTOR HOMOLOG catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 chromosome organization#GO:0051276;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;mitotic sister chromatid cohesion#GO:0007064;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000024630.1|UniProtKB=F6XV63 F6XV63 ARL14 PTHR11711:SF29 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 14 guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553 macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein#PC00020 MONDO|Ensembl=ENSMODG00000007815.4|UniProtKB=F7ETT7 F7ETT7 OTOA PTHR23412:SF18 STEREOCILIN RELATED OTOANCORIN cellular process#GO:0009987;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000019411.4|UniProtKB=H9H8T9 H9H8T9 STAT6 PTHR11801:SF48 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 cellular response to stimulus#GO:0051716;cellular response to peptide hormone stimulus#GO:0071375;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cytokine-mediated signaling pathway#GO:0019221;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to nitrogen compound#GO:1901699;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;defense response#GO:0006952;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to hormone stimulus#GO:0032870;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to peptide#GO:1901652;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;response to stress#GO:0006950;cell surface receptor signaling pathway via STAT#GO:0097696;response to chemical#GO:0042221;response to cytokine#GO:0034097;cell surface receptor signaling pathway#GO:0007166 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561;PDGF signaling pathway#P00047>STAT#P01173;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>STAT#P00832;JAK/STAT signaling pathway#P00038>STAT#P01027 MONDO|Ensembl=ENSMODG00000017355.3|UniProtKB=A0A5F8G4X2 A0A5F8G4X2 ECT2L PTHR46857:SF1 EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 ONCOGENE-LIKE EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 ONCOGENE-LIKE MONDO|Ensembl=ENSMODG00000010271.3|UniProtKB=F6VPD3 F6VPD3 IGDCC3 PTHR10075:SF123 BASIGIN RELATED IMMUNOGLOBULIN SUPERFAMILY DCC SUBCLASS MEMBER 3 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000038103.1|UniProtKB=A8E6F0 A8E6F0 IFN7 PTHR11691:SF37 TYPE I INTERFERON INTERFERON OMEGA-1 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877 defense response to other organism#GO:0098542;lymphocyte activation#GO:0046649;response to chemical#GO:0042221;response to cytokine#GO:0034097;T cell activation involved in immune response#GO:0002286;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;lymphocyte activation involved in immune response#GO:0002285;defense response to symbiont#GO:0140546;B cell activation#GO:0042113;humoral immune response#GO:0006959;immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;natural killer cell activation#GO:0030101;leukocyte activation involved in immune response#GO:0002366;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;T cell activation#GO:0042110;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cell activation involved in immune response#GO:0002263;response to peptide#GO:1901652;B cell activation involved in immune response#GO:0002312;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;multicellular organismal process#GO:0032501;adaptive immune response#GO:0002250;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response#GO:0006955;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cytokine-mediated signaling pathway#GO:0019221;cell activation#GO:0001775 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127;cytokine#PC00083 MONDO|Ensembl=ENSMODG00000044597.1|UniProtKB=A0A5F8H7N3 A0A5F8H7N3 PTHR24377:SF1045 IP01015P-RELATED ZINC FINGER PROTEIN 436 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000012080.4|UniProtKB=F7G4V0 F7G4V0 RCN2 PTHR10827:SF78 RETICULOCALBIN RETICULOCALBIN-2 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000015355.4|UniProtKB=F6WXI5 F6WXI5 DDX51 PTHR24031:SF68 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX51 rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000004889.4|UniProtKB=F7C2J7 F7C2J7 INTS4 PTHR20938:SF0 INTEGRATOR COMPLEX SUBUNIT 4 INTEGRATOR COMPLEX SUBUNIT 4 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;snRNA 3'-end processing#GO:0034472;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;integrator complex#GO:0032039;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000010806.4|UniProtKB=F7BZQ9 F7BZQ9 MYLIP PTHR23280:SF13 4.1 G PROTEIN E3 UBIQUITIN-PROTEIN LIGASE MYLIP catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000023873.3|UniProtKB=F7G9V9 F7G9V9 RAB42 PTHR47979:SF5 DRAB11-RELATED RAS-RELATED PROTEIN RAB-42 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000015885.3|UniProtKB=F7B3W8 F7B3W8 SLC66A1 PTHR16201:SF36 SEVEN TRANSMEMBRANE PROTEIN 1-RELATED LYSOSOMAL AMINO ACID TRANSPORTER 1 HOMOLOG amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;basic amino acid transmembrane transporter activity#GO:0015174;aromatic amino acid transmembrane transporter activity#GO:0015173;L-amino acid transmembrane transporter activity#GO:0015179 amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179;carboxylic acid transmembrane transport#GO:1905039;homeostatic process#GO:0042592;L-alpha-amino acid transmembrane transport#GO:1902475;vacuolar transmembrane transport#GO:0034486;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;chemical homeostasis#GO:0048878;amino acid transport#GO:0006865;transport#GO:0006810;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;vacuole#GO:0005773;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774 MONDO|Ensembl=ENSMODG00000013177.4|UniProtKB=F6ZL55 F6ZL55 TNS4 PTHR45734:SF6 TENSIN TENSIN-4 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000000633.4|UniProtKB=A0A5F8GKD3 A0A5F8GKD3 VCL PTHR46180:SF1 VINCULIN VINCULIN binding#GO:0005488;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;cell-cell contact zone#GO:0044291;adherens junction#GO:0005912 Gonadotropin-releasing hormone receptor pathway#P06664>Vinculin#P06771;Integrin signalling pathway#P00034>Vinculin#P00937 MONDO|Ensembl=ENSMODG00000049908.1|UniProtKB=A0A5F8G9E7 A0A5F8G9E7 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000014630.4|UniProtKB=F6YPQ0 F6YPQ0 ZC3HC1 PTHR15835:SF6 NUCLEAR-INTERACTING PARTNER OF ALK ZINC FINGER C3HC-TYPE PROTEIN 1 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000048403.1|UniProtKB=A0A5F8GAQ4 A0A5F8GAQ4 PTHR24098:SF14 OUTER SEGMENT 5 TRIPARTITE MOTIF-CONTAINING PROTEIN 59 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 intraciliary transport particle#GO:0030990;cilium#GO:0005929;intraciliary transport particle B#GO:0030992;membrane-bounded organelle#GO:0043227;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 MONDO|Ensembl=ENSMODG00000019308.4|UniProtKB=F6RYD9 F6RYD9 COQ2 PTHR11048:SF42 PRENYLTRANSFERASES 4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ubiquinone biosynthetic process#GO:0006744;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle membrane#GO:0031090;cytoplasm#GO:0005737;plasma membrane#GO:0005886;organelle inner membrane#GO:0019866;cell periphery#GO:0071944;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000019900.3|UniProtKB=A0A5F8HE86 A0A5F8HE86 PTHR12084:SF0 NUCLEAR PORE GLYCOPROTEIN P62-RELATED NUCLEAR PORE GLYCOPROTEIN P62 binding#GO:0005488;phospholipid binding#GO:0005543;structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198;lipid binding#GO:0008289 import into nucleus#GO:0051170;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;localization#GO:0051179;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nucleocytoplasmic transport#GO:0006913 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 MONDO|Ensembl=ENSMODG00000007234.2|UniProtKB=F6WC95 F6WC95 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028126.2|UniProtKB=K7E3P8 K7E3P8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000040064.1|UniProtKB=A0A5F8GSD6 A0A5F8GSD6 LOC100028314 PTHR48002:SF74 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000029761.2|UniProtKB=K7E6A4 K7E6A4 PTHR10105:SF4 SELENOPROTEIN P SELENOPROTEIN P2 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000008923.4|UniProtKB=F7GL67 F7GL67 RPL21 PTHR20981:SF6 60S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN EL21 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000002601.4|UniProtKB=A0A5F8HBY5 A0A5F8HBY5 GLIPR2 PTHR10334:SF581 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1 positive regulation of developmental process#GO:0051094;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000020206.2|UniProtKB=F7FXU9 F7FXU9 CBLIF PTHR10559:SF15 TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR COBALAMIN BINDING INTRINSIC FACTOR binding#GO:0005488;small molecule binding#GO:0036094;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363 localization#GO:0051179;establishment of localization#GO:0051234;vitamin transport#GO:0051180;transport#GO:0006810;nitrogen compound transport#GO:0071705 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000002607.4|UniProtKB=F7G4Q7 F7G4Q7 UXS1 PTHR43078:SF54 UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED UDP-GLUCURONIC ACID DECARBOXYLASE 1 carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleotide-sugar metabolic process#GO:0009225;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;organophosphate biosynthetic process#GO:0090407 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 lyase#PC00144;decarboxylase#PC00089 MONDO|Ensembl=ENSMODG00000028583.2|UniProtKB=K7E0G3 K7E0G3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000005784.4|UniProtKB=F6XG60 F6XG60 LGI1 PTHR24367:SF17 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH GLIOMA-INACTIVATED PROTEIN 1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000003602.4|UniProtKB=F7C6L2 F7C6L2 PTHR46145:SF1 HEPARANASE INACTIVE HEPARANASE-2 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000019986.3|UniProtKB=F6RPF9 F6RPF9 LOC100021052 PTHR48018:SF121 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5D18 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038169.1|UniProtKB=A0A5F8GN36 A0A5F8GN36 PTHR16675:SF67 MHC CLASS I-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000002666.3|UniProtKB=F7DHW1 F7DHW1 CHRNG PTHR18945:SF60 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT GAMMA passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;muscle contraction#GO:0006936;system process#GO:0003008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;acetylcholine receptor signaling pathway#GO:0095500;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;synaptic transmission, cholinergic#GO:0007271;neuromuscular process#GO:0050905;trans-synaptic signaling#GO:0099537;response to nitrogen compound#GO:1901698;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;striated muscle contraction#GO:0006941;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;synaptic signaling#GO:0099536;response to chemical#GO:0042221;nervous system process#GO:0050877;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;muscle system process#GO:0003012;skeletal muscle contraction#GO:0003009;signaling#GO:0023052;response to stimulus#GO:0050896 transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cell junction#GO:0030054;transporter complex#GO:1990351;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>gamma#P01094 MONDO|Ensembl=ENSMODG00000015851.3|UniProtKB=F7F0D8 F7F0D8 GTF2H4 PTHR13152:SF0 TFIIH, POLYPEPTIDE 4 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 4 nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;RNA metabolic process#GO:0016070;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;response to stimulus#GO:0050896;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleotide-excision repair#GO:0006289;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;transferase complex#GO:1990234;transcription factor TFIIH core complex#GO:0000439;transcription regulator complex#GO:0005667;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription factor TFIIH holo complex#GO:0005675;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription regulation#P00023>TFIIH complex#P00664;Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392 MONDO|Ensembl=ENSMODG00000011868.3|UniProtKB=F7G2V5 F7G2V5 CAVIN2 PTHR15240:SF1 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 2 protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 intracellular anatomical structure#GO:0005622;plasma membrane raft#GO:0044853;membrane microdomain#GO:0098857;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane raft#GO:0045121;caveola#GO:0005901;membrane#GO:0016020 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000006626.3|UniProtKB=F7GEK1 F7GEK1 AKT3 PTHR24356:SF190 SERINE/THREONINE-PROTEIN KINASE RAC-GAMMA SERINE_THREONINE-PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell motility#GO:2000145;cell communication#GO:0007154;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;cellular response to insulin stimulus#GO:0032869;regulation of cell migration#GO:0030334;negative regulation of cellular process#GO:0048523;positive regulation of locomotion#GO:0040017;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;negative regulation of apoptotic process#GO:0043066;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of programmed cell death#GO:0043067;positive regulation of cell motility#GO:2000147;negative regulation of biological process#GO:0048519;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;response to hormone#GO:0009725;response to chemical#GO:0042221 non-receptor serine/threonine protein kinase#PC00167 Huntington disease#P00029>Akt#P00805;p53 pathway#P00059>Akt#P01486;Endothelin signaling pathway#P00019>Akt#P00589;Angiogenesis#P00005>Akt#P00223;FGF signaling pathway#P00021>Akt#P00632;Hypoxia response via HIF activation#P00030>AKT#P00819;p53 pathway feedback loops 2#P04398>AKT#P04665;p53 pathway by glucose deprivation#P04397>Akt#P04641;T cell activation#P00053>Akt#P01332;PI3 kinase pathway#P00048>PKB#P01179;Ras Pathway#P04393>AKT#P04570;Interleukin signaling pathway#P00036>PKB#P00973;EGF receptor signaling pathway#P00018>Akt#P00551;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AKT#P00827;Apoptosis signaling pathway#P00006>AKT#P00260 MONDO|Ensembl=ENSMODG00000028693.2|UniProtKB=K7E636 K7E636 PTHR22442:SF4 FAMILY NOT NAMED PROTEIN FAM169BP MONDO|Ensembl=ENSMODG00000009890.4|UniProtKB=F6VCE1 F6VCE1 NAT10 PTHR10925:SF5 N-ACETYLTRANSFERASE 10 RNA CYTIDINE ACETYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on RNA#GO:0140098;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a tRNA#GO:0140101 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble base modification#GO:0002097;rRNA modification#GO:0000154;tRNA modification#GO:0006400;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000048273.1|UniProtKB=K7E655 K7E655 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000018620.4|UniProtKB=F7B318 F7B318 SLC25A36 PTHR45829:SF2 MITOCHONDRIAL CARRIER PROTEIN RIM2 SOLUTE CARRIER FAMILY 25 MEMBER 36 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 MONDO|Ensembl=ENSMODG00000027650.2|UniProtKB=K7E696 K7E696 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000016857.4|UniProtKB=A0A5F8G764 A0A5F8G764 ROBO1 PTHR12231:SF243 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN ROUNDABOUT HOMOLOG 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;cell recognition#GO:0008037;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure development#GO:0048856 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cell leading edge#GO:0031252;membrane#GO:0016020;main axon#GO:0044304;neuron projection#GO:0043005;cell periphery#GO:0071944;cell projection membrane#GO:0031253;axon#GO:0030424;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 Axon guidance mediated by Slit/Robo#P00008>Robo#P00348 MONDO|Ensembl=ENSMODG00000024012.2|UniProtKB=F6YQ19 F6YQ19 RIOX1 PTHR13096:SF8 MINA53 MYC INDUCED NUCLEAR ANTIGEN RIBOSOMAL OXYGENASE 1 protein demethylase activity#GO:0140457;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000001031.4|UniProtKB=F6ZF69 F6ZF69 GATB PTHR11659:SF5 GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;translation#GO:0006412;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 ligase#PC00142;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000050169.1|UniProtKB=A0A5F8GA41 A0A5F8GA41 VN2R568 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000022707.3|UniProtKB=A0A5F8GXX4 A0A5F8GXX4 AGRN PTHR15036:SF83 PIKACHURIN-LIKE PROTEIN AGRIN molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;protein kinase activator activity#GO:0030295;signaling receptor regulator activity#GO:0030545;enzyme activator activity#GO:0008047;neurotransmitter receptor regulator activity#GO:0099602;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;acetylcholine receptor regulator activity#GO:0030548;kinase activator activity#GO:0019209 localization within membrane#GO:0051668;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;localization#GO:0051179;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;developmental process#GO:0032502;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;receptor clustering#GO:0043113;animal gross anatomical part developmental process#GO:0160108;cellular localization#GO:0051641;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;signaling#GO:0023052;response to stimulus#GO:0050896;neuromuscular junction development#GO:0007528;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;synaptic signaling#GO:0099536;nervous system development#GO:0007399 extracellular region#GO:0005576;cell junction#GO:0030054;external encapsulating structure#GO:0030312;membrane#GO:0016020;extracellular matrix#GO:0031012;basement membrane#GO:0005604;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000017809.4|UniProtKB=F6ZY15 F6ZY15 VGLL2 PTHR15950:SF17 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 2 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000004435.4|UniProtKB=F6RTY4 F6RTY4 SLC44A3 PTHR12385:SF13 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098 MONDO|Ensembl=ENSMODG00000038487.1|UniProtKB=A0A5F8GPZ4 A0A5F8GPZ4 H2AZ2 PTHR23430:SF280 HISTONE H2A HISTONE H2A.V structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789 intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000008195.4|UniProtKB=F7DJR0 F7DJR0 MPP7 PTHR23122:SF39 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 7 localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to cell junction#GO:1902414 plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013709.4|UniProtKB=F6Y9G1 F6Y9G1 KDM7A PTHR23123:SF15 PHD/F-BOX CONTAINING PROTEIN LYSINE-SPECIFIC DEMETHYLASE 7A histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;protein demethylase activity#GO:0140457 cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000005868.4|UniProtKB=A0A5F8HCA8 A0A5F8HCA8 DNM1 PTHR11566:SF32 DYNAMIN DYNAMIN-1 ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;hydrolase activity#GO:0016787;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;microtubule binding#GO:0008017;GTPase activity#GO:0003924 organelle localization#GO:0051640;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;synaptic vesicle endocytosis#GO:0048488;establishment of organelle localization#GO:0051656;endocytosis#GO:0006897;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;synaptic vesicle transport#GO:0048489;organelle organization#GO:0006996;membrane organization#GO:0061024;establishment of vesicle localization#GO:0051650;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479 intracellular organelle#GO:0043229;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 membrane traffic protein#PC00150 Gonadotropin-releasing hormone receptor pathway#P06664>Dnm1#P06781;CCKR signaling map#P06959>Dynamin#P07100 MONDO|Ensembl=ENSMODG00000039010.1|UniProtKB=A0A5F8HAQ4 A0A5F8HAQ4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000022876.1|UniProtKB=F6WZF2 F6WZF2 LOC100024277 PTHR26450:SF40 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56A3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015263.5|UniProtKB=A0A5F8GSZ4 A0A5F8GSZ4 GOLGA3 PTHR18902:SF26 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED GOLGIN SUBFAMILY A MEMBER 3 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000016320.5|UniProtKB=F7FL50 F7FL50 KPNA4 PTHR23316:SF7 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-3 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;protein localization to organelle#GO:0033365 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 MONDO|Ensembl=ENSMODG00000015056.4|UniProtKB=F7FUK4 F7FUK4 NIF3L1 PTHR13799:SF13 NGG1 INTERACTING FACTOR 3 NIF3-LIKE PROTEIN 1 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000004977.4|UniProtKB=F7FKS4 F7FKS4 MOGAT3 PTHR12317:SF36 DIACYLGLYCEROL O-ACYLTRANSFERASE 2-ACYLGLYCEROL O-ACYLTRANSFERASE 3 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 neutral lipid metabolic process#GO:0006638;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;biosynthetic process#GO:0009058;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;primary metabolic process#GO:0044238 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 acyltransferase#PC00042;transferase#PC00220 MONDO|Ensembl=ENSMODG00000009286.4|UniProtKB=A0A5F8GRC8 A0A5F8GRC8 PRDX3 PTHR10681:SF182 THIOREDOXIN PEROXIDASE THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE, MITOCHONDRIAL oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601 hydrogen peroxide metabolic process#GO:0042743;homeostatic process#GO:0042592;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular process#GO:0009987;response to stress#GO:0006950;cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;response to oxidative stress#GO:0006979;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 peroxidase#PC00180;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000038986.1|UniProtKB=A0A5F8H0A4 A0A5F8H0A4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000001081.4|UniProtKB=F7E7X7 F7E7X7 PLIN3 PTHR14024:SF11 PERILIPIN PERILIPIN-3 regulation of localization#GO:0032879;cellular process#GO:0009987;lipid storage#GO:0019915;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;membraneless organelle#GO:0043228;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018273.4|UniProtKB=A0A5F8H8T0 A0A5F8H8T0 ANKRD6 PTHR24203:SF84 ANKYRIN REPEAT FAMILY PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 6 establishment or maintenance of cell polarity#GO:0007163;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular process#GO:0009987 Wnt signaling pathway#P00057>Diversin#P01466 MONDO|Ensembl=ENSMODG00000013670.4|UniProtKB=F6TXA4 F6TXA4 DENND2A PTHR15288:SF3 DENN DOMAIN-CONTAINING PROTEIN 2 DENN DOMAIN-CONTAINING PROTEIN 2A guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000014719.3|UniProtKB=F7D2Y1 F7D2Y1 LOC100013602 PTHR24235:SF16 NEUROPEPTIDE Y RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 6-RELATED neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000007876.2|UniProtKB=F7EB65 F7EB65 LOC100618713 PTHR48002:SF88 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006309.4|UniProtKB=F7BR31 F7BR31 ITGBL1 PTHR10082:SF3 INTEGRIN BETA SUBUNIT INTEGRIN BETA-LIKE PROTEIN 1 protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;cell migration#GO:0016477;cell surface receptor signaling pathway#GO:0007166;cell adhesion mediated by integrin#GO:0033627 focal adhesion#GO:0005925;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;anchoring junction#GO:0070161;integrin complex#GO:0008305;cell junction#GO:0030054;signaling receptor complex#GO:0043235 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 MONDO|Ensembl=ENSMODG00000005241.1|UniProtKB=F6YNM5 F6YNM5 SPAG7 PTHR13498:SF3 SPERM ASSOCIATED ANTIGEN 7 SPERM-ASSOCIATED ANTIGEN 7 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000024351.2|UniProtKB=F7B4Q2 F7B4Q2 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003113.4|UniProtKB=F6ZXS4 F6ZXS4 HTRA3 PTHR22939:SF14 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA3 catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;cell death#GO:0008219;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;protein metabolic process#GO:0019538;proteolysis#GO:0006508;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;macromolecule metabolic process#GO:0043170;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000005310.4|UniProtKB=A0A5F8H9Y5 A0A5F8H9Y5 TANK PTHR15249:SF0 TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR Toll receptor signaling pathway#P00054>TANK#P01353 MONDO|Ensembl=ENSMODG00000007411.3|UniProtKB=F7GKI3 F7GKI3 B3GNTL1 PTHR22916:SF73 GLYCOSYLTRANSFERASE QUEUOSINE-TRNA GALACTOSYLTRANSFERASE catalytic activity, acting on a tRNA#GO:0140101;galactosyltransferase activity#GO:0008378;catalytic activity, acting on RNA#GO:0140098;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000016562.2|UniProtKB=F7DN69 F7DN69 NPEPL1 PTHR11963:SF4 LEUCINE AMINOPEPTIDASE-RELATED AMINOPEPTIDASE NPEPL1-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000000803.4|UniProtKB=F6S9T7 F6S9T7 PHTF1 PTHR12680:SF8 PUTATIVE HOMEODOMAIN TRANSCRIPTION FACTOR PHTF PROTEIN PHTF1 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000036384.1|UniProtKB=A0A5F8GQS6 A0A5F8GQS6 ANKRD66 PTHR24201:SF15 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 66 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 MONDO|Ensembl=ENSMODG00000003726.4|UniProtKB=F7EVU7 F7EVU7 LOXL4 PTHR45817:SF5 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 4 oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 oxidase#PC00175;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000018799.4|UniProtKB=F6ZMY3 F6ZMY3 ADAMTSL4 PTHR13723:SF144 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 4 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152;external encapsulating structure organization#GO:0045229;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000010327.4|UniProtKB=A0A5F8HKR9 A0A5F8HKR9 INPP5K PTHR11200:SF117 INOSITOL 5-PHOSPHATASE INOSITOL POLYPHOSPHATE 5-PHOSPHATASE K catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of polysaccharide metabolic process#GO:0032881;regulation of signal transduction#GO:0009966;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of response to stimulus#GO:0048583;regulation of glycogen biosynthetic process#GO:0005979;negative regulation of cellular process#GO:0048523;regulation of carbohydrate metabolic process#GO:0006109;regulation of cell communication#GO:0010646;negative regulation of metabolic process#GO:0009892;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;ruffle#GO:0001726;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505 phosphatase#PC00181;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000001905.2|UniProtKB=F6W1R5 F6W1R5 SENP8 PTHR46468:SF1 SENTRIN-SPECIFIC PROTEASE 8 SENTRIN-SPECIFIC PROTEASE 8 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190 MONDO|Ensembl=ENSMODG00000007427.3|UniProtKB=F7EDV8 F7EDV8 PDK3 PTHR11947:SF21 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 3, MITOCHONDRIAL phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of lipid metabolic process#GO:0019216;regulation of carbohydrate metabolic process#GO:0006109;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000039629.1|UniProtKB=A0A5F8GCM6 A0A5F8GCM6 PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN binding#GO:0005488;signaling receptor binding#GO:0005102;peptide binding#GO:0042277;antigen binding#GO:0003823;protein binding#GO:0005515 regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000023385.2|UniProtKB=F6U684 F6U684 PTHR11406:SF0 PHOSPHOGLYCERATE KINASE PHOSPHOGLYCERATE KINASE kinase activity#GO:0016301;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;phosphoglycerate kinase activity#GO:0004618;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;nucleobase-containing compound catabolic process#GO:0034655;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;small molecule biosynthetic process#GO:0044283;energy derivation by oxidation of organic compounds#GO:0015980;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;ribonucleoside diphosphate metabolic process#GO:0009185;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;oxoacid metabolic process#GO:0043436;gluconeogenesis#GO:0006094;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;monocarboxylic acid metabolic process#GO:0032787;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;pyruvate metabolic process#GO:0006090;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate biosynthetic process#GO:0016051;ADP catabolic process#GO:0046032;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphoglycerate kinase#P00671 MONDO|Ensembl=ENSMODG00000050252.1|UniProtKB=A0A5F8G9P4 A0A5F8G9P4 LOC100012510 PTHR26451:SF98 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10T2 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000044379.1|UniProtKB=A0A5F8GTJ0 A0A5F8GTJ0 HDHD2 PTHR19288:SF46 4-NITROPHENYLPHOSPHATASE-RELATED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000023429.1|UniProtKB=F6XI83 F6XI83 HTR1E PTHR24247:SF33 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1E neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 dendrite#GO:0030425;dendritic tree#GO:0097447;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 MONDO|Ensembl=ENSMODG00000043982.1|UniProtKB=A0A5F8GIV2 A0A5F8GIV2 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000001415.4|UniProtKB=F7BD00 F7BD00 GTF2H2C PTHR12695:SF2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;RNA metabolic process#GO:0016070;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;response to stimulus#GO:0050896 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transcription factor TFIIH holo complex#GO:0005675;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II, holoenzyme#GO:0016591;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;transferase complex#GO:1990234;transcription factor TFIIH core complex#GO:0000439;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000015805.4|UniProtKB=F7FEB8 F7FEB8 MME PTHR11733:SF114 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000008490.4|UniProtKB=F7G448 F7G448 SF3B2 PTHR12785:SF19 SPLICING FACTOR 3B SPLICING FACTOR 3B SUBUNIT 2 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2 snRNP#GO:0005686;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000000455.2|UniProtKB=A0A5F8G6C5 A0A5F8G6C5 PTHR11699:SF233 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 cellular response to chemical stimulus#GO:0070887;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular detoxification of aldehyde#GO:0110095;cellular response to stimulus#GO:0051716;metabolic process#GO:0008152;response to chemical#GO:0042221;cellular response to toxic substance#GO:0097237;aldehyde catabolic process#GO:0046185;detoxification#GO:0098754;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 MONDO|Ensembl=ENSMODG00000001872.4|UniProtKB=F6S6D6 F6S6D6 HEXB PTHR22600:SF38 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE SUBUNIT BETA hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;sphingolipid catabolic process#GO:0030149;glycosaminoglycan metabolic process#GO:0030203;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;ceramide metabolic process#GO:0006672;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 lysosome#GO:0005764;cell periphery#GO:0071944;membrane#GO:0016020;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323 glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000015352.4|UniProtKB=A0A5F8GGG0 A0A5F8GGG0 CD274 PTHR25466:SF3 T-LYMPHOCYTE ACTIVATION ANTIGEN PROGRAMMED CELL DEATH 1 LIGAND 1 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 negative regulation of cell communication#GO:0010648;immune system process#GO:0002376;negative regulation of signaling#GO:0023057;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;immune response#GO:0006955 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000000308.4|UniProtKB=A0A5F8GT99 A0A5F8GT99 INPP4B PTHR12187:SF3 AGAP000124-PA INOSITOL POLYPHOSPHATE 4-PHOSPHATASE TYPE II hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896 cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000039825.1|UniProtKB=A0A5F8G3C2 A0A5F8G3C2 RCAN2 PTHR10300:SF5 CALCIPRESSIN CALCIPRESSIN-2 protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;cell communication#GO:0007154;calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000016498.5|UniProtKB=H9H6X0 H9H6X0 PTHR47979:SF69 DRAB11-RELATED RAS-RELATED PROTEIN RAB-39B protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;myosin binding#GO:0017022;pyrophosphatase activity#GO:0016462 cellular process#GO:0009987;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000029652.2|UniProtKB=K7E5B6 K7E5B6 PTHR16515:SF51 PR DOMAIN ZINC FINGER PROTEIN ZINC FINGER PROTEIN 936 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000041302.1|UniProtKB=A0A5F8H3S6 A0A5F8H3S6 PTHR23262:SF50 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-8 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000007858.3|UniProtKB=F7EBI2 F7EBI2 RCE1 PTHR13046:SF0 PROTEASE U48 CAAX PRENYL PROTEASE RCE1 CAAX PRENYL PROTEASE 2 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000015919.3|UniProtKB=F6ZRB2 F6ZRB2 LSMEM1 PTHR36475:SF1 LEUCINE-RICH SINGLE-PASS MEMBRANE PROTEIN 1 LEUCINE-RICH SINGLE-PASS MEMBRANE PROTEIN 1 MONDO|Ensembl=ENSMODG00000000178.2|UniProtKB=F6TGC2 F6TGC2 PTHR28520:SF15 MITOTIC-SPINDLE ORGANIZING PROTEIN 1 MITOTIC-SPINDLE ORGANIZING PROTEIN 1 chromosome segregation#GO:0007059;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;nuclear division#GO:0000280;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;microtubule nucleation#GO:0007020;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;mitotic spindle organization#GO:0007052;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;microtubule polymerization#GO:0046785;spindle organization#GO:0007051;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;microtubule polymerization or depolymerization#GO:0031109;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000018784.4|UniProtKB=F7AD72 F7AD72 HMGCLL1 PTHR42738:SF5 HYDROXYMETHYLGLUTARYL-COA LYASE 3-HYDROXY-3-METHYLGLUTARYL-COA LYASE, CYTOPLASMIC lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 lyase#PC00144 MONDO|Ensembl=ENSMODG00000028904.2|UniProtKB=K7E2Z8 K7E2Z8 LOC100033109 PTHR11177:SF405 CHITINASE ACIDIC MAMMALIAN CHITINASE chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000021037.4|UniProtKB=F6W0F9 F6W0F9 AGPAT3 PTHR10983:SF9 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE GAMMA acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000036475.1|UniProtKB=A0A5F8H8C4 A0A5F8H8C4 CREG2 PTHR13343:SF15 CREG1 PROTEIN PROTEIN CREG2 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000017256.4|UniProtKB=F6TJZ5 F6TJZ5 ENTPD2 PTHR11782:SF33 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 2 hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 metabolic process#GO:0008152;nucleoside diphosphate metabolic process#GO:0009132;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate catabolic process#GO:0046434;nucleoside diphosphate catabolic process#GO:0009134;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 nucleotide phosphatase#PC00173;hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000037511.1|UniProtKB=F7D893 F7D893 LOC100618597 PTHR26453:SF271 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2V1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009057.4|UniProtKB=A0A5F8GWR4 A0A5F8GWR4 MAPK15 PTHR24055:SF79 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 15 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 PDGF signaling pathway#P00047>ERK#P01143;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Interleukin signaling pathway#P00036>ERK#P00965;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Parkinson disease#P00049>ERK#P01211;EGF receptor signaling pathway#P00018>ERK1-2#P00543 MONDO|Ensembl=ENSMODG00000009028.4|UniProtKB=A0A5F8HE45 A0A5F8HE45 SPARC PTHR13866:SF6 SPARC OSTEONECTIN SPARC ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 inner ear development#GO:0048839;inner ear morphogenesis#GO:0042472;tube development#GO:0035295;embryo development#GO:0009790;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental process#GO:0032502;sensory organ development#GO:0007423;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;tube morphogenesis#GO:0035239;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;sensory organ morphogenesis#GO:0090596;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of cellular component organization#GO:0051128;regulation of synapse organization#GO:0050807;embryonic organ development#GO:0048568;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;ear development#GO:0043583;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000013265.4|UniProtKB=A0A5F8H5W7 A0A5F8H5W7 AIFM1 PTHR43557:SF4 APOPTOSIS-INDUCING FACTOR 1 APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;small molecule binding#GO:0036094 transport#GO:0006810;intracellular transport#GO:0046907;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;apoptotic process#GO:0006915;cellular process#GO:0009987;cell death#GO:0008219;establishment of localization in cell#GO:0051649;programmed cell death#GO:0012501;mitochondrial protein import pathway#GO:7770058;mitochondrial transport#GO:0006839 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176 Apoptosis signaling pathway#P00006>AIF#P00286 MONDO|Ensembl=ENSMODG00000048683.1|UniProtKB=F7G3G0 F7G3G0 LOC100024435 PTHR26450:SF425 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56A1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005158.3|UniProtKB=F7EPT2 F7EPT2 PPAN PTHR12661:SF5 PETER PAN-RELATED SUPPRESSOR OF SWI4 1 HOMOLOG RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 preribosome, large subunit precursor#GO:0030687;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000012867.3|UniProtKB=F7C958 F7C958 PTHR23267:SF511 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-9 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000000845.4|UniProtKB=F7BIQ2 F7BIQ2 LOC100010951 PTHR24264:SF15 TRYPSIN-RELATED TRYPSIN catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000014187.4|UniProtKB=A0A5F8GJ41 A0A5F8GJ41 BCAS3 PTHR13268:SF0 BREAST CARCINOMA AMPLIFIED SEQUENCE 3 BCAS3 MICROTUBULE ASSOCIATED CELL MIGRATION FACTOR enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 metabolic process#GO:0008152;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;cellular component organization#GO:0016043;response to stress#GO:0006950;response to nutrient levels#GO:0031667;response to starvation#GO:0042594;organelle organization#GO:0006996;macroautophagy#GO:0016236;response to stimulus#GO:0050896;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;phagophore assembly site#GO:0000407 non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000001217.4|UniProtKB=F7G7R5 F7G7R5 AK4 PTHR23359:SF58 NUCLEOTIDE KINASE ADENYLATE KINASE 4, MITOCHONDRIAL nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 MONDO|Ensembl=ENSMODG00000016264.4|UniProtKB=A0A5F8G870 A0A5F8G870 BCHE PTHR43918:SF5 ACETYLCHOLINESTERASE CHOLINESTERASE hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067 MONDO|Ensembl=ENSMODG00000008356.3|UniProtKB=F7EK41 F7EK41 PTHR46315:SF1 SPERMINE SYNTHASE SPERMINE SYNTHASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 polyamine biosynthetic process#GO:0006596;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;metabolic process#GO:0008152;amine metabolic process#GO:0009308;polyamine metabolic process#GO:0006595;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000037588.1|UniProtKB=A0A5F8GHG0 A0A5F8GHG0 PTHR15858:SF7 IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1 IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1 regulation of biological process#GO:0050789;regulation of protein secretion#GO:0050708;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;positive regulation of secretion#GO:0051047;positive regulation of cellular component organization#GO:0051130;localization#GO:0051179;regulation of secretion#GO:0051046;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of secretion by cell#GO:1903530;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;positive regulation of protein secretion#GO:0050714;establishment of localization#GO:0051234;regulation of localization#GO:0032879;regulation of transport#GO:0051049 membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000050583.1|UniProtKB=K7E428 K7E428 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007112.5|UniProtKB=A0A5F8G3H0 A0A5F8G3H0 STAU2 PTHR46054:SF1 MATERNAL EFFECT PROTEIN STAUFEN DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 2 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725 sexual reproduction#GO:0019953;microtubule-based transport#GO:0099111;protein localization to cell junction#GO:1902414;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;cellular localization#GO:0051641;localization#GO:0051179;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;RNA localization#GO:0006403;microtubule-based movement#GO:0007018;cell differentiation#GO:0030154;transport#GO:0006810;developmental process#GO:0032502;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;transport along microtubule#GO:0010970;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;protein localization to synapse#GO:0035418;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;axo-dendritic transport#GO:0008088;macromolecule localization#GO:0033036;cytoskeleton-dependent intracellular transport#GO:0030705 membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;cell body#GO:0044297 MONDO|Ensembl=ENSMODG00000040540.1|UniProtKB=A0A5F8GC35 A0A5F8GC35 MRPL13 PTHR11545:SF45 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of translation#GO:0017148;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000009741.3|UniProtKB=F6X9J9 F6X9J9 XPO7 PTHR12596:SF11 EXPORTIN 4,7-RELATED EXPORTIN-7 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein export from nucleus#GO:0006611;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913 nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 transporter#PC00227 MONDO|Ensembl=ENSMODG00000001154.4|UniProtKB=A0A5F8G2T5 A0A5F8G2T5 TG PTHR14093:SF19 HLA CLASS II GAMMA CHAIN THYROGLOBULIN regulation of biological quality#GO:0065008;metabolic process#GO:0008152;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;phenol-containing compound metabolic process#GO:0018958;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000048070.1|UniProtKB=A0A5F8HC29 A0A5F8HC29 CGGBP1 PTHR32344:SF1 U1-TYPE DOMAIN-CONTAINING PROTEIN U1-TYPE DOMAIN-CONTAINING PROTEIN regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000008064.4|UniProtKB=F6YKA6 F6YKA6 ELAC2 PTHR12553:SF49 ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101 macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mitochondrial RNA 3'-end processing#GO:0000965;tRNA 3'-end processing#GO:0042780;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA 3'-end processing#GO:0031123;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000015713.5|UniProtKB=A0A5F8GQF7 A0A5F8GQF7 TAOK2 PTHR48015:SF7 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE TAO2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;intracellular signaling cassette#GO:0141124;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000039421.1|UniProtKB=K7DZL3 K7DZL3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000040981.1|UniProtKB=F7G2M8 F7G2M8 IMPACT PTHR16301:SF25 IMPACT-RELATED PROTEIN IMPACT cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of translational initiation#GO:0006446;cellular response to stress#GO:0033554;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000025595.3|UniProtKB=F6WPW3 F6WPW3 LOC103105947 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of immune response#GO:0050776;signaling#GO:0023052;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000012908.4|UniProtKB=F7GKQ0 F7GKQ0 OR6X1 PTHR26454:SF30 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6X1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003407.5|UniProtKB=F7GL20 F7GL20 DMRT3 PTHR12322:SF120 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 3 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 sex differentiation#GO:0007548;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000006780.3|UniProtKB=F7BTG6 F7BTG6 HECTD2 PTHR45622:SF56 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HECTD2-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 MONDO|Ensembl=ENSMODG00000005831.4|UniProtKB=F6U1T6 F6U1T6 PTHR43677:SF4 SHORT-CHAIN DEHYDROGENASE/REDUCTASE PROTEIN CRYZL2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176 Huntington disease#P00029>PIG3#G01535 MONDO|Ensembl=ENSMODG00000014330.4|UniProtKB=F6V4X4 F6V4X4 APOOL PTHR14564:SF3 MICOS COMPLEX SUBUNIT MIC26 / MIC27 FAMILY MEMBER MICOS COMPLEX SUBUNIT MIC27 inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;mitochondrial membrane organization#GO:0007006;cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;cellular component organization or biogenesis#GO:0071840 inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000004521.3|UniProtKB=F6UR33 F6UR33 RPUSD4 PTHR21600:SF81 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE RPUSD4, MITOCHONDRIAL isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000000680.4|UniProtKB=A0A5F8GAI6 A0A5F8GAI6 SLC9A3 PTHR10110:SF90 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 3 metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079 inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;import into cell#GO:0098657;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873 cell projection membrane#GO:0031253;cluster of actin-based cell projections#GO:0098862;apical part of cell#GO:0045177;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;brush border membrane#GO:0031526;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;apical plasma membrane#GO:0016324;membrane#GO:0016020;cell periphery#GO:0071944;brush border#GO:0005903 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000051418.1|UniProtKB=A0A5F8GJB8 A0A5F8GJB8 CHMP6 PTHR22761:SF5 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 6 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;endosome transport via multivesicular body sorting pathway#GO:0032509;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;nucleus organization#GO:0006997;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;nuclear envelope organization#GO:0006998;endosomal transport#GO:0016197;cellular component organization#GO:0016043;membrane assembly#GO:0071709;late endosome to vacuole transport#GO:0045324;cellular localization#GO:0051641;localization#GO:0051179 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;late endosome#GO:0005770;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;nucleus#GO:0005634;membrane#GO:0016020;vesicle membrane#GO:0012506 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000042313.1|UniProtKB=A0A5F8HGB5 A0A5F8HGB5 DYNLT5 PTHR21255:SF64 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 5 binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000038585.1|UniProtKB=M9MMH1 M9MMH1 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000041486.1|UniProtKB=A0A5F8GR28 A0A5F8GR28 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000046227.1|UniProtKB=A0A5F8HE06 A0A5F8HE06 PTHR37151:SF1 TRANSMEMBRANE PROTEIN 61 TRANSMEMBRANE PROTEIN 61 MONDO|Ensembl=ENSMODG00000006552.4|UniProtKB=F7BUY1 F7BUY1 ENTPD5 PTHR11782:SF35 ADENOSINE/GUANOSINE DIPHOSPHATASE NUCLEOSIDE DIPHOSPHATE PHOSPHATASE ENTPD5 nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside diphosphate catabolic process#GO:0009134;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside diphosphate metabolic process#GO:0009132;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 hydrolase#PC00121;nucleotide phosphatase#PC00173;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000037786.1|UniProtKB=A0A5F8GFZ6 A0A5F8GFZ6 TMED7 PTHR22811:SF117 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 7 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 cellular component organization#GO:0016043;Golgi organization#GO:0007030;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 vesicle#GO:0031982;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150;vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000038857.1|UniProtKB=A0A5F8HH92 A0A5F8HH92 LOC100024986 PTHR10271:SF28 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 5 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 defense response to virus#GO:0051607;cellular response to cytokine stimulus#GO:0071345;antiviral innate immune response#GO:0140374;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;immune system process#GO:0002376;response to virus#GO:0009615;response to peptide#GO:1901652;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to cytokine#GO:0034097;response to chemical#GO:0042221;defense response to other organism#GO:0098542;response to other organism#GO:0051707;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000009694.4|UniProtKB=F6YBD7 F6YBD7 ISLR PTHR24366:SF14 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS IMMUNOGLOBULIN SUPERFAMILY CONTAINING LEUCINE-RICH REPEAT PROTEIN regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of cell projection organization#GO:0031346;regulation of nervous system development#GO:0051960;regulation of growth#GO:0040008;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;positive regulation of cell differentiation#GO:0045597;regulation of anatomical structure size#GO:0090066;regulation of axonogenesis#GO:0050770;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of cell growth#GO:0030307;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;regulation of cell growth#GO:0001558;positive regulation of cellular component organization#GO:0051130;positive regulation of growth#GO:0045927;regulation of cell size#GO:0008361;regulation of biological quality#GO:0065008;positive regulation of axonogenesis#GO:0050772;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128 immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000010935.4|UniProtKB=F7EPD8 F7EPD8 KANSL1 PTHR22443:SF14 NON-SPECIFIC LETHAL 1, ISOFORM M KAT8 REGULATORY NSL COMPLEX SUBUNIT 1 binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515 chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;NSL complex#GO:0044545 MONDO|Ensembl=ENSMODG00000011997.3|UniProtKB=F7B924 F7B924 GATA4 PTHR10071:SF154 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANSCRIPTION FACTOR GATA-4 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>GATA2/4#P06859 MONDO|Ensembl=ENSMODG00000039115.1|UniProtKB=A0A5F8HD18 A0A5F8HD18 PTHR11769:SF23 HYALURONIDASE HYALURONIDASE-1 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;glycosaminoglycan catabolic process#GO:0006027;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000039512.1|UniProtKB=A0A5F8GNR9 A0A5F8GNR9 PTHR26450:SF124 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012495.3|UniProtKB=A0A5F8GPB9 A0A5F8GPB9 PTHR16875:SF0 SELENOPROTEIN K SELENOPROTEIN K biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;regulation of response to stimulus#GO:0048583;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological process#GO:0050789;calcium ion homeostasis#GO:0055074;regulation of intracellular signal transduction#GO:1902531;inorganic ion homeostasis#GO:0098771;regulation of signaling#GO:0023051 Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000046189.1|UniProtKB=A0A5F8G5Z1 A0A5F8G5Z1 OLFM3 PTHR23192:SF36 OLFACTOMEDIN-RELATED NOELIN-3 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000004253.4|UniProtKB=F6TW64 F6TW64 EED PTHR10253:SF12 POLYCOMB PROTEIN POLYCOMB PROTEIN EED enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;chromatin binding#GO:0003682;binding#GO:0005488;nucleosome binding#GO:0031491;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234 regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 nucleus#GO:0005634;PcG protein complex#GO:0031519;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000001701.3|UniProtKB=F6S6U5 F6S6U5 SLC16A4 PTHR11360:SF14 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 5-RELATED monocarboxylic acid transmembrane transporter activity#GO:0008028;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000020554.3|UniProtKB=F7AQ30 F7AQ30 LIAS PTHR10949:SF0 LIPOYL SYNTHASE LIPOYL SYNTHASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 Lipoate_biosynthesis#P02750>Lipoate synthase#P03004 MONDO|Ensembl=ENSMODG00000012694.4|UniProtKB=F6UYP3 F6UYP3 CRB1 PTHR24049:SF1 CRUMBS FAMILY MEMBER PROTEIN CRUMBS HOMOLOG 1 heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;establishment or maintenance of bipolar cell polarity#GO:0061245;cell adhesion#GO:0007155;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment or maintenance of cell polarity#GO:0007163 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000014188.4|UniProtKB=F6U6P0 F6U6P0 T2R2 PTHR11394:SF57 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 2 bitter taste receptor activity#GO:0033038;molecular transducer activity#GO:0060089;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004096.5|UniProtKB=A0A5F8HA94 A0A5F8HA94 MCF2L PTHR22826:SF115 RHO GUANINE EXCHANGE FACTOR-RELATED GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000042324.1|UniProtKB=A0A5F8GG42 A0A5F8GG42 LOC100020907 PTHR48018:SF170 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5D3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011389.3|UniProtKB=F6SNS1 F6SNS1 MGAT2 PTHR12871:SF0 BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE II ALPHA-1,6-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000018132.3|UniProtKB=F6U6Y5 F6U6Y5 GPR63 PTHR24245:SF1 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 63-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018409.3|UniProtKB=F6Q9E0 F6Q9E0 POPC1 PTHR10211:SF0 DEOXYRIBODIPYRIMIDINE PHOTOLYASE DEOXYRIBODIPYRIMIDINE PHOTO-LYASE catalytic activity#GO:0003824;deoxyribodipyrimidine photo-lyase activity#GO:0003904;catalytic activity, acting on a nucleic acid#GO:0140640;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;catalytic activity, acting on DNA#GO:0140097 nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;pyrimidine dimer repair#GO:0006290;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170;photoreactive repair#GO:0000719 lyase#PC00144 MONDO|Ensembl=ENSMODG00000020492.4|UniProtKB=F7F542 F7F542 SLC6A15 PTHR11616:SF101 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT2 symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873 metal ion transport#GO:0030001;L-leucine transport#GO:0015820;sodium ion transport#GO:0006814;monoatomic cation transport#GO:0006812;localization#GO:0051179;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;establishment of localization#GO:0051234;branched-chain amino acid transport#GO:0015803;organic acid transport#GO:0015849;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 MONDO|Ensembl=ENSMODG00000007336.4|UniProtKB=F7B0Q5 F7B0Q5 PGM2L1 PTHR45745:SF2 PHOSPHOMANNOMUTASE 45A GLUCOSE 1,6-BISPHOSPHATE SYNTHASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;intramolecular phosphotransferase activity#GO:0016868;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;small molecule biosynthetic process#GO:0044283;purine nucleoside metabolic process#GO:0042278;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;purine-containing compound biosynthetic process#GO:0072522 mutase#PC00160;isomerase#PC00135;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000011900.5|UniProtKB=F7EGZ4 F7EGZ4 TLX1 PTHR45921:SF2 IP01054P T-CELL LEUKEMIA HOMEOBOX PROTEIN 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 animal gross anatomical part developmental process#GO:0160108;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000012840.4|UniProtKB=F7CTL3 F7CTL3 PTHR24404:SF56 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 281 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000041275.1|UniProtKB=A0A5F8HJR1 A0A5F8HJR1 LOC100012726 PTHR12348:SF23 TSC22 TSC22 DOMAIN FAMILY PROTEIN 1 molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000010712.4|UniProtKB=A0A5F8H2D5 A0A5F8H2D5 GULP1 PTHR11232:SF78 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PTB DOMAIN-CONTAINING ENGULFMENT ADAPTER PROTEIN 1 signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 membrane invagination#GO:0010324;transport#GO:0006810;phagocytosis#GO:0006909;phagocytosis, engulfment#GO:0006911;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular process#GO:0009987;cellular component organization#GO:0016043;membrane organization#GO:0061024;endocytosis#GO:0006897 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010470.3|UniProtKB=F7ET56 F7ET56 LOC100030495 PTHR26451:SF42 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10R2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000028753.2|UniProtKB=K7E274 K7E274 LOC103101138 PTHR11654:SF91 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 5 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000039287.1|UniProtKB=A0A5F8GYW1 A0A5F8GYW1 PLA2G2C PTHR11716:SF5 PHOSPHOLIPASE A2 FAMILY MEMBER INACTIVE GROUP IIC SECRETORY PHOSPHOLIPASE A2-RELATED glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;protein binding#GO:0005515;lipid binding#GO:0008289;catalytic activity#GO:0003824;phospholipid binding#GO:0005543;hydrolase activity, acting on ester bonds#GO:0016788;small molecule binding#GO:0036094;lipase activity#GO:0016298;signaling receptor binding#GO:0005102;ion binding#GO:0043167;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169 organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;glycerolipid metabolic process#GO:0046486;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;phosphatidylglycerol metabolic process#GO:0046471;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000028101.2|UniProtKB=K7E1N3 K7E1N3 BTBD19 PTHR46965:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 19 BTB_POZ DOMAIN-CONTAINING PROTEIN 19 MONDO|Ensembl=ENSMODG00000004179.5|UniProtKB=A0A5F8GIU6 A0A5F8GIU6 PRPF40A PTHR11864:SF20 PRE-MRNA-PROCESSING PROTEIN PRP40 PRE-MRNA-PROCESSING FACTOR 40 HOMOLOG A nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;U2-type prespliceosome#GO:0071004;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000001673.3|UniProtKB=A0A5F8GYG8 A0A5F8GYG8 PSME4 PTHR32170:SF5 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4 peptidase regulator activity#GO:0061134;peptidase activator activity#GO:0016504;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 proteasome complex#GO:0000502;nucleus#GO:0005634;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 MONDO|Ensembl=ENSMODG00000023755.2|UniProtKB=F6TEG4 F6TEG4 PTHR47046:SF1 SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex II assembly#GO:0034553;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000012352.4|UniProtKB=F7E1V0 F7E1V0 SATB2 PTHR15116:SF15 DNA-BINDING PROTEIN SATB FAMILY MEMBER DNA-BINDING PROTEIN SATB2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000049774.1|UniProtKB=A0A5F8H7W7 A0A5F8H7W7 PTHR23268:SF13 T-CELL RECEPTOR BETA CHAIN IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000015967.3|UniProtKB=F7FDC6 F7FDC6 RPP21 PTHR14742:SF0 RIBONUCLEASE P SUBUNIT P21 RIBONUCLEASE P PROTEIN SUBUNIT P21 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonuclease P complex#GO:0030677;endoribonuclease complex#GO:1902555;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleolar ribonuclease P complex#GO:0005655;multimeric ribonuclease P complex#GO:0030681;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000010575.4|UniProtKB=F7GI16 F7GI16 DPH1 PTHR10762:SF1 DIPHTHAMIDE BIOSYNTHESIS PROTEIN 2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;metabolic process#GO:0008152;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000013066.2|UniProtKB=A0A5F8GA63 A0A5F8GA63 LOC100018407 PTHR22850:SF90 WD40 REPEAT FAMILY HISTONE-BINDING PROTEIN RBBP4 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;histone deacetylase complex#GO:0000118;PcG protein complex#GO:0031519;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667 MONDO|Ensembl=ENSMODG00000023271.3|UniProtKB=A0A5F8G967 A0A5F8G967 MPC1 PTHR14154:SF3 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;monocarboxylic acid transmembrane transporter activity#GO:0008028 carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular localization#GO:0051641;transport#GO:0006810;mitochondrial transmembrane transport#GO:1990542;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;intracellular transport#GO:0046907 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740 MONDO|Ensembl=ENSMODG00000028400.2|UniProtKB=K7E4X7 K7E4X7 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008625.3|UniProtKB=F7F1N5 F7F1N5 RASSF10 PTHR15286:SF13 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 10 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007771.1|UniProtKB=F7AWZ6 F7AWZ6 MRPL38 PTHR11362:SF133 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN LARGE RIBOSOMAL SUBUNIT PROTEIN ML38 membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000046046.1|UniProtKB=A0A5F8GL51 A0A5F8GL51 COL8A1 PTHR24023:SF903 COLLAGEN ALPHA COLLAGEN ALPHA-1(VIII) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000012586.4|UniProtKB=F6PIX9 F6PIX9 GSC PTHR46643:SF2 HOMEOBOX PROTEIN GOOSECOID-RELATED HOMEOBOX PROTEIN GOOSECOID sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000005122.4|UniProtKB=A0A5F8G3U6 A0A5F8G3U6 ACTR6 PTHR11937:SF47 ACTIN ACTIN-RELATED PROTEIN 6 chromatin binding#GO:0003682;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleosome binding#GO:0031491;structural molecule activity#GO:0005198;protein-containing complex binding#GO:0044877 chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;nucleolus organization#GO:0007000 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Swr1 complex#GO:0000812;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233 actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000018466.4|UniProtKB=F7CAU3 F7CAU3 TUBA8 PTHR11588:SF140 TUBULIN TUBULIN ALPHA-8 CHAIN carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 cytoskeletal protein#PC00085;tubulin#PC00228 MONDO|Ensembl=ENSMODG00000012001.4|UniProtKB=F7B8Z0 F7B8Z0 PCSK6 PTHR42884:SF8 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 6 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;proteolysis#GO:0006508;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;hormone metabolic process#GO:0042445;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;biological regulation#GO:0065007;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;peptide hormone processing#GO:0016486 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;cell surface#GO:0009986;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;Alzheimer disease-presenilin pathway#P00004>Furin#P00157 MONDO|Ensembl=ENSMODG00000009743.4|UniProtKB=F6X9H5 F6X9H5 STRA6 PTHR21444:SF16 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 RECEPTOR FOR RETINOL UPTAKE STRA6 macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810;lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000014057.4|UniProtKB=F6U8L7 F6U8L7 PTHR17554:SF2 TYRO PROTEIN TYROSINE KINASE-BINDING PROTEIN TYRO PROTEIN TYROSINE KINASE-BINDING PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 positive regulation of cellular component organization#GO:0051130;cell activation involved in immune response#GO:0002263;regulation of leukocyte activation#GO:0002694;negative regulation of gene expression#GO:0010629;regulation of cell activation#GO:0050865;negative regulation of metabolic process#GO:0009892;regulation of lymphocyte activation#GO:0051249;positive regulation of leukocyte activation#GO:0002696;immune effector process#GO:0002252;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stress#GO:0006950;regulation of B cell activation#GO:0050864;myeloid leukocyte activation#GO:0002274;regulation of multicellular organismal process#GO:0051239;microglial cell activation#GO:0001774;inflammatory response#GO:0006954;cell activation#GO:0001775;regulation of leukocyte mediated cytotoxicity#GO:0001910;leukocyte activation#GO:0045321;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of leukocyte mediated immunity#GO:0002705;macrophage activation#GO:0042116;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;immune system process#GO:0002376;regulation of cell killing#GO:0031341;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of B cell proliferation#GO:0030888;leukocyte activation involved in immune response#GO:0002366;regulation of leukocyte proliferation#GO:0070663;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of lymphocyte activation#GO:0051250;negative regulation of leukocyte activation#GO:0002695;regulation of cell population proliferation#GO:0042127;positive regulation of lymphocyte activation#GO:0051251;regulation of immune effector process#GO:0002697;negative regulation of multicellular organismal process#GO:0051241;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;negative regulation of cell activation#GO:0050866;regulation of biosynthetic process#GO:0009889;defense response#GO:0006952;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;negative regulation of cell population proliferation#GO:0008285;immune response#GO:0006955;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of lymphocyte proliferation#GO:0050670;multicellular organismal process#GO:0032501;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;positive regulation of cell activation#GO:0050867;positive regulation of immune effector process#GO:0002699 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007121.4|UniProtKB=F6SHB7 F6SHB7 CDR2L PTHR19232:SF10 CENTROCORTIN FAMILY MEMBER CEREBELLAR DEGENERATION-RELATED PROTEIN 2-LIKE MONDO|Ensembl=ENSMODG00000008795.5|UniProtKB=A0A5F8H125 A0A5F8H125 WASF3 PTHR12902:SF7 WASP-1 ACTIN-BINDING PROTEIN WASF3 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;protein kinase A regulatory subunit binding#GO:0034237;protein kinase A binding#GO:0051018;binding#GO:0005488 biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;cellular component organization or biogenesis#GO:0071840;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cellular component organization#GO:0016043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;actin filament-based process#GO:0030029 intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cell leading edge#GO:0031252 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000002322.3|UniProtKB=F6YD76 F6YD76 LOC100019208 PTHR23188:SF12 RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;chromatin binding#GO:0003682;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175 transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000020430.4|UniProtKB=F7AR94 F7AR94 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000044033.1|UniProtKB=A0A5F8G4F5 A0A5F8G4F5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000017221.4|UniProtKB=F6WXT3 F6WXT3 TOR4A PTHR10760:SF1 TORSIN TORSIN-4A intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endomembrane system#GO:0012505;nucleus#GO:0005634;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum#GO:0005783 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000044284.1|UniProtKB=A0A5F8H029 A0A5F8H029 PTHR13947:SF48 GNAT FAMILY N-ACETYLTRANSFERASE N-ACETYLTRANSFERASE 8-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000017528.4|UniProtKB=A0A5F8GFC7 A0A5F8GFC7 KPNA6 PTHR23316:SF8 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-7 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;nucleocytoplasmic transport#GO:0006913;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 MONDO|Ensembl=ENSMODG00000000965.3|UniProtKB=F7ESZ6 F7ESZ6 RHOQ PTHR24072:SF13 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOQ hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein kinase binding#GO:0019901;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;transport#GO:0006810;actin filament organization#GO:0007015;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;establishment of cell polarity#GO:0030010;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020;small GTPase#PC00208 Huntington disease#P00029>Rac#P00775;EGF receptor signaling pathway#P00018>Rac#P00564 MONDO|Ensembl=ENSMODG00000018275.4|UniProtKB=F6Q6M0 F6Q6M0 RRAGD PTHR11259:SF5 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN D ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265 cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;positive regulation of intracellular signal transduction#GO:1902533;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;negative regulation of autophagy#GO:0010507;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;response to nutrient levels#GO:0031667;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of TOR signaling#GO:0032008;negative regulation of catabolic process#GO:0009895;response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892 nucleus#GO:0005634;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000012742.4|UniProtKB=A0A5F8GPM8 A0A5F8GPM8 FGD4 PTHR12673:SF98 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 4 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;filopodium assembly#GO:0046847;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000004763.4|UniProtKB=F6WW16 F6WW16 FLI1 PTHR11849:SF161 ETS FRIEND LEUKEMIA INTEGRATION 1 TRANSCRIPTION FACTOR DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 MONDO|Ensembl=ENSMODG00000016107.4|UniProtKB=F7EB10 F7EB10 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 organelle organization#GO:0006996;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;telomere organization#GO:0032200;telomere maintenance#GO:0000723;chromosome organization#GO:0051276 MONDO|Ensembl=ENSMODG00000012875.4|UniProtKB=A0A5F8GEI9 A0A5F8GEI9 GRB7 PTHR11243:SF25 GROWTH FACTOR RECEPTOR-BOUND PROTEIN GROWTH FACTOR RECEPTOR-BOUND PROTEIN 7 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;negative regulation of signal transduction#GO:0009968;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;cell surface receptor signaling pathway#GO:0007166;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to peptide hormone#GO:0043434;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;cellular response to nitrogen compound#GO:1901699;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Grb7#P00228 MONDO|Ensembl=ENSMODG00000007284.4|UniProtKB=F7FCJ1 F7FCJ1 FBLN1 PTHR24050:SF29 PA14 DOMAIN-CONTAINING PROTEIN FIBULIN-1 MONDO|Ensembl=ENSMODG00000019589.4|UniProtKB=F6Y8U7 F6Y8U7 MRPS11 PTHR11759:SF76 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 SMALL RIBOSOMAL SUBUNIT PROTEIN US11M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000025384.2|UniProtKB=F6YK28 F6YK28 LOC100031316 PTHR26452:SF247 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5K3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012779.5|UniProtKB=A0A5F8HFY6 A0A5F8HFY6 RALGAPA1 PTHR10063:SF3 TUBERIN RAL GTPASE-ACTIVATING PROTEIN SUBUNIT ALPHA-1 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124 G-protein modulator#PC00022;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000004430.4|UniProtKB=F6SCF1 F6SCF1 SLC27A1 PTHR43107:SF7 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 1 carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;transporter activity#GO:0005215;catalytic activity#GO:0003824;monocarboxylic acid transmembrane transporter activity#GO:0008028 lipid transport#GO:0006869;long-chain fatty acid metabolic process#GO:0001676;macromolecule localization#GO:0033036;cellular process#GO:0009987;import into cell#GO:0098657;establishment of localization#GO:0051234;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid metabolic process#GO:0006629;organic acid transport#GO:0015849;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;fatty acid transport#GO:0015908;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;oxoacid metabolic process#GO:0043436 endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000037049.1|UniProtKB=A0A5F8H8Z4 A0A5F8H8Z4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000006561.4|UniProtKB=F7BUK3 F7BUK3 POP1 PTHR22731:SF3 RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1 RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;ribonuclease P activity#GO:0004526;catalytic activity, acting on a tRNA#GO:0140101;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;rRNA metabolic process#GO:0016072;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;endonuclease complex#GO:1905348;protein-containing complex#GO:0032991;ribonuclease MRP complex#GO:0000172;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonuclease P complex#GO:0030677;endoribonuclease complex#GO:1902555;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;multimeric ribonuclease P complex#GO:0030681;nucleolar ribonuclease P complex#GO:0005655;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 endoribonuclease#PC00094;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000019500.3|UniProtKB=F6VUS0 F6VUS0 REM1 PTHR45775:SF2 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C GTP-BINDING PROTEIN REM 1 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;calcium channel regulator activity#GO:0005246;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;transporter regulator activity#GO:0141108 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000013104.5|UniProtKB=A0A5F8H882 A0A5F8H882 EVL PTHR11202:SF4 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER ENA_VASP-LIKE PROTEIN protein binding#GO:0005515;binding#GO:0005488 regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of supramolecular fiber organization#GO:1902903;supramolecular fiber organization#GO:0097435;system development#GO:0048731;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection guidance#GO:0097485;actin filament organization#GO:0007015;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of actin filament-based process#GO:0032970;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;neuron development#GO:0048666;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;generation of neurons#GO:0048699;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of anatomical structure size#GO:0090066 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cell junction#GO:0030054;anchoring junction#GO:0070161 scaffold/adaptor protein#PC00226 Cytoskeletal regulation by Rho GTPase#P00016>Ena/VASP#P00516 MONDO|Ensembl=ENSMODG00000012984.4|UniProtKB=F7CS77 F7CS77 GPX1 PTHR11592:SF41 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 1 catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;sulfur compound metabolic process#GO:0006790;response to reactive oxygen species#GO:0000302;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;hydrogen peroxide metabolic process#GO:0042743;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;modified amino acid metabolic process#GO:0006575;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;glutathione metabolic process#GO:0006749;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;peroxidase#PC00180 MONDO|Ensembl=ENSMODG00000036587.1|UniProtKB=A0A5F8GPI6 A0A5F8GPI6 QTRT2 PTHR46064:SF1 QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2 QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2 RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000015378.4|UniProtKB=F6TLC0 F6TLC0 WASL PTHR48125:SF12 LP07818P1 CONSERVED GLUTAMIC ACID RICH PROTEIN (AFU_ORTHOLOGUE AFUA_5G09010)-RELATED Cytoskeletal regulation by Rho GTPase#P00016>N-WASP#P00525;Huntington disease#P00029>N-Wasp#P00769 MONDO|Ensembl=ENSMODG00000036689.1|UniProtKB=A0A5F8HIJ4 A0A5F8HIJ4 LOC103096117 PTHR35968:SF1 CHROMOSOME 6 C6ORF201 HOMOLOG TESTIS EXPRESSED PROTEIN 56 MONDO|Ensembl=ENSMODG00000002921.4|UniProtKB=F6PMR4 F6PMR4 TBX19 PTHR11267:SF114 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX19 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 anatomical structure formation involved in morphogenesis#GO:0048646;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;mesoderm development#GO:0007498;animal organ development#GO:0048513;cell fate specification#GO:0001708;embryo development#GO:0009790;heart development#GO:0007507;cellular process#GO:0009987;cell fate commitment#GO:0045165;formation of primary germ layer#GO:0001704;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;circulatory system development#GO:0072359;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;gastrulation#GO:0007369;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;mesoderm formation#GO:0001707;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;tissue morphogenesis#GO:0048729;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;heart morphogenesis#GO:0003007;mesoderm morphogenesis#GO:0048332 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 MONDO|Ensembl=ENSMODG00000018325.4|UniProtKB=F6UPB5 F6UPB5 SEMA5B PTHR11036:SF39 SEMAPHORIN SEMAPHORIN-5B signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;developmental cell growth#GO:0048588;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;cellular developmental process#GO:0048869;developmental growth#GO:0048589;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron projection extension#GO:1990138;axonogenesis#GO:0007409;developmental growth involved in morphogenesis#GO:0060560;neuron development#GO:0048666;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;axon extension#GO:0048675;cell surface receptor signaling pathway#GO:0007166;growth#GO:0040007;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell growth#GO:0016049;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000018304.4|UniProtKB=F6PVJ1 F6PVJ1 ORC3 PTHR12748:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170 organelle lumen#GO:0043233;chromosome#GO:0005694;DNA replication preinitiation complex#GO:0031261;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;pre-replicative complex#GO:0036387;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nuclear pre-replicative complex#GO:0005656;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;nuclear origin of replication recognition complex#GO:0005664;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;origin recognition complex#GO:0000808 replication origin binding protein#PC00199;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000027439.2|UniProtKB=K7DZ04 K7DZ04 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003576.4|UniProtKB=A0A5F8HAK4 A0A5F8HAK4 CNNM1 PTHR12064:SF28 METAL TRANSPORTER CNNM METAL TRANSPORTER CNNM1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000004074.4|UniProtKB=F7AF21 F7AF21 POLN PTHR10133:SF65 DNA POLYMERASE I DNA POLYMERASE NU transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887 nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302 DNA-directed DNA polymerase#PC00018 MONDO|Ensembl=ENSMODG00000037771.1|UniProtKB=A0A5F8GQI6 A0A5F8GQI6 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011503.4|UniProtKB=F6WZ55 F6WZ55 DOCK11 PTHR23317:SF81 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 11 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of cell projection organization#GO:0031344;regulation of response to stimulus#GO:0048583;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of filopodium assembly#GO:0051489;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cell projection organization#GO:0031346;positive regulation of cellular component organization#GO:0051130;regulation of cell projection assembly#GO:0060491;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000008177.4|UniProtKB=A0A5F8HFQ4 A0A5F8HFQ4 BCLAF3 PTHR15268:SF17 THRAP3/BCLAF1 BCLAF1 AND THRAP3 FAMILY MEMBER 3 DNA binding#GO:0003677;transcription coregulator activity#GO:0003712;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000013379.3|UniProtKB=F7DT85 F7DT85 SHC3 PTHR10337:SF4 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;trans-synaptic signaling#GO:0099537;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell surface receptor signaling pathway#GO:0007166 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Shc#P01175;FGF signaling pathway#P00021>Shc#P00639;EGF receptor signaling pathway#P00018>Shc#P00554 MONDO|Ensembl=ENSMODG00000000350.3|UniProtKB=F6RUG0 F6RUG0 KCNG3 PTHR11537:SF91 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL REGULATORY SUBUNIT KCNG3 ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;potassium ion transport#GO:0006813;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;action potential#GO:0001508;metal ion transport#GO:0030001;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 voltage-gated ion channel#PC00241;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000019396.2|UniProtKB=H9H7C4 H9H7C4 RDH16 PTHR43313:SF11 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 16 alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455 small molecule metabolic process#GO:0044281;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;cellular process#GO:0009987;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000004815.4|UniProtKB=F6V5F1 F6V5F1 SLC46A2 PTHR23507:SF3 ZGC:174356 SOLUTE CARRIER FAMILY 46 MEMBER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000001141.2|UniProtKB=A0A5F8GHR8 A0A5F8GHR8 ACOD1 PTHR16943:SF11 2-METHYLCITRATE DEHYDRATASE-RELATED CIS-ACONITATE DECARBOXYLASE catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;primary metabolic process#GO:0044238;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;regulation of immune response#GO:0050776;negative regulation of immune response#GO:0050777;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;defense response#GO:0006952;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;lipid metabolic process#GO:0006629;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;fatty acid metabolic process#GO:0006631;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;regulation of biological process#GO:0050789;carboxylic acid metabolic process#GO:0019752;negative regulation of biological process#GO:0048519;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436;negative regulation of innate immune response#GO:0045824;negative regulation of response to external stimulus#GO:0032102;regulation of response to external stimulus#GO:0032101;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;positive regulation of response to external stimulus#GO:0032103;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lyase#PC00144;dehydratase#PC00091 MONDO|Ensembl=ENSMODG00000038856.1|UniProtKB=A0A5F8G1Y6 A0A5F8G1Y6 KICS2 PTHR31581:SF1 KICSTOR COMPLEX PROTEIN C12ORF66 KICSTOR SUBUNIT 2 negative regulation of biological process#GO:0048519;protein localization to lysosome#GO:0061462;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;response to stress#GO:0006950;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;cellular response to amino acid starvation#GO:0034198;negative regulation of signal transduction#GO:0009968;negative regulation of TORC1 signaling#GO:1904262;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;negative regulation of TOR signaling#GO:0032007;regulation of cell communication#GO:0010646;protein localization to vacuole#GO:0072665;localization#GO:0051179;macromolecule localization#GO:0033036;response to nutrient levels#GO:0031667;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;regulation of TORC1 signaling#GO:1903432;intracellular protein localization#GO:0008104 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000010307.4|UniProtKB=F6SS12 F6SS12 COG6 PTHR21506:SF0 COMPONENT OF OLIGOMERIC GOLGI COMPLEX 6 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 6 organelle organization#GO:0006996;retrograde transport, vesicle recycling within Golgi#GO:0000301;cellular component organization#GO:0016043;Golgi organization#GO:0007030;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;COG complex#GO:0017119;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000011184.2|UniProtKB=A0A5F8GRY2 A0A5F8GRY2 PTHR11593:SF10 60S RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN UL22 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000040841.1|UniProtKB=F6WNH5 F6WNH5 PTHR21297:SF0 DNA-DIRECTED RNA POLYMERASE II DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 translation initiation factor binding#GO:0031369;protein binding#GO:0005515;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 MONDO|Ensembl=ENSMODG00000037949.1|UniProtKB=A0A5F8GGS7 A0A5F8GGS7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000029247.2|UniProtKB=K7E345 K7E345 PTHR23036:SF190 CYTOKINE RECEPTOR GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR RECEPTOR SUBUNIT ALPHA cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515 cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;negative regulation of neuron apoptotic process#GO:0043524;biological regulation#GO:0065007;response to chemical#GO:0042221;negative regulation of apoptotic process#GO:0043066;response to cytokine#GO:0034097 extracellular protein-containing complex#GO:0140392;signaling receptor complex#GO:0043235;extracellular region#GO:0005576;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003917.3|UniProtKB=F7CNT6 F7CNT6 PTHR14350:SF2 ARGININE VASOPRESSIN-INDUCED PROTEIN 1 ARGININE VASOPRESSIN-INDUCED PROTEIN 1 positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 MONDO|Ensembl=ENSMODG00000050755.1|UniProtKB=A0A5F8HLF3 A0A5F8HLF3 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000040836.1|UniProtKB=A0A5F8GLD8 A0A5F8GLD8 PTHR34644:SF2 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 MONDO|Ensembl=ENSMODG00000018083.3|UniProtKB=F7FTI4 F7FTI4 LOC103106071 PTHR16073:SF9 DCR DOMAIN-CONTAINING PROTEIN DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED PROTEIN 4 chromatin binding#GO:0003682;binding#GO:0005488 developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;system development#GO:0048731 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000048620.1|UniProtKB=A0A5F8H651 A0A5F8H651 EVA1C PTHR46780:SF4 PROTEIN EVA-1 PROTEIN EVA-1 HOMOLOG C heparin binding#GO:0008201;binding#GO:0005488;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000043414.1|UniProtKB=A0A5F8HH81 A0A5F8HH81 PTHR28626:SF3 SRR1-LIKE PROTEIN SRR1-LIKE PROTEIN intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000015017.5|UniProtKB=F7BXG8 F7BXG8 CNTNAP1 PTHR15036:SF43 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN 1 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;nervous system development#GO:0007399;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;myelination#GO:0042552 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000039613.1|UniProtKB=A0A5F8GN49 A0A5F8GN49 PTHR24043:SF10 SCAVENGER RECEPTOR CLASS F MULTIPLE EGF LIKE DOMAINS 6 cargo receptor activity#GO:0038024 cell-cell adhesion#GO:0098609;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell adhesion#GO:0007155 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000045421.1|UniProtKB=A0A5F8HFR1 A0A5F8HFR1 DYNLT4 PTHR21255:SF55 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 4 binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;dynein complex#GO:0030286;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000047559.1|UniProtKB=A0A5F8GSW1 A0A5F8GSW1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008074.3|UniProtKB=F6YJR4 F6YJR4 LAMTOR1 PTHR13401:SF2 RAGULATOR COMPLEX PROTEIN LAMTOR1 RAGULATOR COMPLEX PROTEIN LAMTOR1 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;response to acid chemical#GO:0001101;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;positive regulation of MAPK cascade#GO:0043410;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531 membrane#GO:0016020;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;vacuole#GO:0005773;cytoplasm#GO:0005737;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000001983.4|UniProtKB=F7FXK4 F7FXK4 IMPG2 PTHR12199:SF4 INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN 2 organic acid binding#GO:0043177;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;glycosaminoglycan binding#GO:0005539;ion binding#GO:0043167;heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000014333.4|UniProtKB=A0A5F8GVN9 A0A5F8GVN9 PTHR12673:SF14 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 3 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;filopodium assembly#GO:0046847;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000024125.3|UniProtKB=A0A5F8G5W9 A0A5F8G5W9 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000003534.4|UniProtKB=F7GBR1 F7GBR1 RPL17 PTHR11593:SF10 60S RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN UL22 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000006616.3|UniProtKB=F7GEV0 F7GEV0 SSU72 PTHR20383:SF9 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;termination of RNA polymerase II transcription#GO:0006369;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;nucleus#GO:0005634 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000012400.3|UniProtKB=F6PN08 F6PN08 INKA1 PTHR28615:SF1 PAK4-INHIBITOR INKA1-RELATED PAK4-INHIBITOR INKA1 protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase inhibitor activity#GO:0019210;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;protein kinase regulator activity#GO:0019887;enzyme inhibitor activity#GO:0004857 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000023052.3|UniProtKB=A0A5F8GGP9 A0A5F8GGP9 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010552.4|UniProtKB=F6YRM6 F6YRM6 GIGYF2 PTHR14445:SF38 GRB10 INTERACTING GYF PROTEIN GRB10-INTERACTING GYF PROTEIN 2 translation regulator activity#GO:0045182 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;negative regulation of protein metabolic process#GO:0051248;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;insulin-like growth factor receptor signaling pathway#GO:0048009;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558 perikaryon#GO:0043204;membrane#GO:0016020;cytosol#GO:0005829;neuron projection#GO:0043005;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;cell body#GO:0044297;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025 MONDO|Ensembl=ENSMODG00000001392.4|UniProtKB=F7F5P3 F7F5P3 WDR1 PTHR19856:SF8 WD-REPEATCONTAINING PROTEIN WDR1 WD REPEAT-CONTAINING PROTEIN 1 actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;protein-containing complex organization#GO:0043933;striated muscle cell differentiation#GO:0051146;cellular anatomical entity morphogenesis#GO:0032989;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;actin filament depolymerization#GO:0030042;cellular component disassembly#GO:0022411;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;actin filament organization#GO:0007015;developmental process#GO:0032502;protein depolymerization#GO:0051261;actin polymerization or depolymerization#GO:0008154;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;protein-containing complex disassembly#GO:0032984;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000023911.1|UniProtKB=F7C2X6 F7C2X6 PAQR7 PTHR20855:SF41 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR ALPHA transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;lipid binding#GO:0008289;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;steroid binding#GO:0005496 response to chemical#GO:0042221;response to stimulus#GO:0050896;response to lipid#GO:0033993;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;response to steroid hormone#GO:0048545 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000028433.2|UniProtKB=A0A5F8G9X1 A0A5F8G9X1 PTHR24381:SF269 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 398 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020265.4|UniProtKB=F7C1C3 F7C1C3 EMB PTHR10075:SF4 BASIGIN RELATED EMBIGIN cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000018267.3|UniProtKB=F6Q774 F6Q774 MRPL17 PTHR14413:SF24 RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN BL17M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;mitochondrial translation#GO:0032543;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412 intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000031558.2|UniProtKB=A0A5F8GAL7 A0A5F8GAL7 PTHR42985:SF10 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 1 monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic ion transport#GO:0006811;monocarboxylic acid transport#GO:0015718;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;fatty acid transport#GO:0015908;lipid localization#GO:0010876;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000002465.3|UniProtKB=A0A5F8G1V8 A0A5F8G1V8 PTHR10877:SF136 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-1-LIKE PROTEIN 3 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 detection of stimulus#GO:0051606;detection of mechanical stimulus#GO:0050982;response to abiotic stimulus#GO:0009628;response to mechanical stimulus#GO:0009612;response to stimulus#GO:0050896;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000015616.3|UniProtKB=F6Z507 F6Z507 RNF181 PTHR15710:SF243 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF181 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000006911.3|UniProtKB=F6PT54 F6PT54 CLRN3 PTHR31548:SF3 CLARIN CLARIN-3 MONDO|Ensembl=ENSMODG00000006425.4|UniProtKB=F7EZJ5 F7EZJ5 ZER1 PTHR12904:SF23 FAMILY NOT NAMED PROTEIN ZER-1 HOMOLOG Cul2-RING ubiquitin ligase complex#GO:0031462;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000002420.4|UniProtKB=F7EGU4 F7EGU4 PSMD2 PTHR10943:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;proteasome complex#GO:0000502;nucleus#GO:0005634;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;endopeptidase complex#GO:1905369;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000006009.4|UniProtKB=A0A5F8HI43 A0A5F8HI43 SLC38A11 PTHR22950:SF708 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;L-amino acid transmembrane transporter activity#GO:0015179 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 amino acid transporter#PC00046;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000001067.4|UniProtKB=F6YQX4 F6YQX4 KEL PTHR11733:SF128 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED KELL BLOOD GROUP GLYCOPROTEIN hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;biological regulation#GO:0065007;protein maturation#GO:0051604;gene expression#GO:0010467;hormone metabolic process#GO:0042445;cellular process#GO:0009987;protein processing#GO:0016485;peptide hormone processing#GO:0016486;macromolecule biosynthetic process#GO:0009059;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;proteolysis#GO:0006508;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000044994.1|UniProtKB=F7GBI2 F7GBI2 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000000042.3|UniProtKB=F6S0A7 F6S0A7 THEM6 PTHR12475:SF4 FAMILY NOT NAMED PROTEIN THEM6 MONDO|Ensembl=ENSMODG00000011257.4|UniProtKB=F6R1B3 F6R1B3 GNL3 PTHR11089:SF11 GTP-BINDING PROTEIN-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000006498.4|UniProtKB=F7EK35 F7EK35 ACADVL PTHR43884:SF11 ACYL-COA DEHYDROGENASE VERY LONG-CHAIN ACYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824;lipid binding#GO:0008289;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 lipid modification#GO:0030258;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000000846.4|UniProtKB=F7BIR5 F7BIR5 PRPSAP2 PTHR10210:SF29 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE-ASSOCIATED PROTEIN 2 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 MONDO|Ensembl=ENSMODG00000042095.1|UniProtKB=A0A5F8G6L6 A0A5F8G6L6 RDH14 PTHR24320:SF285 RETINOL DEHYDROGENASE RETINOL DEHYDROGENASE 14 oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 oxidoreductase#PC00176;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000000401.4|UniProtKB=A0A5F8GF54 A0A5F8GF54 LPAR3 PTHR22750:SF21 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 3 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000041532.1|UniProtKB=A0A5F8GN97 A0A5F8GN97 PTHR19446:SF479 REVERSE TRANSCRIPTASES RNA-DIRECTED DNA POLYMERASE viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000004745.4|UniProtKB=F6XJA7 F6XJA7 PTHR45888:SF1 HL01030P-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE 2C N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone H3 methyltransferase activity#GO:0140938;histone H3K4 methyltransferase activity#GO:0042800;protein methyltransferase activity#GO:0008276;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;histone methyltransferase activity#GO:0042054;transcription regulator activity#GO:0140110;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;transcription coactivator activity#GO:0003713 regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000000742.4|UniProtKB=F6VPY4 F6VPY4 RSBN1 PTHR13354:SF8 ROUND SPERMATID BASIC PROTEIN 1 LYSINE-SPECIFIC DEMETHYLASE 9 histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213;protein demethylase activity#GO:0140457;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000022647.2|UniProtKB=H9H8A5 H9H8A5 PTHR24373:SF262 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012373.4|UniProtKB=F7DHJ7 F7DHJ7 AMTN PTHR36858:SF1 AMELOTIN AMELOTIN MONDO|Ensembl=ENSMODG00000010183.2|UniProtKB=F6SUK3 F6SUK3 DKK4 PTHR12113:SF10 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 4 signaling receptor regulator activity#GO:0030545;binding#GO:0005488;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;signaling receptor inhibitor activity#GO:0030547;protein binding#GO:0005515 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000003621.3|UniProtKB=A0A5F8HDH7 A0A5F8HDH7 PTHR12884:SF36 60S RIBOSOMAL PROTEIN L29 60S RIBOSOMAL PROTEIN L29 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000020816.3|UniProtKB=F6RN02 F6RN02 CTU1 PTHR11807:SF12 ATPASES OF THE PP SUPERFAMILY-RELATED CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;tRNA binding#GO:0000049 nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;tRNA thio-modification#GO:0034227;macromolecule modification#GO:0043412;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble position uridine thiolation#GO:0002143;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytosol#GO:0005829;sulfurtransferase complex#GO:1990228;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000020372.3|UniProtKB=F7F6G2 F7F6G2 PTHR15838:SF1 NUCLEOLAR PROTEIN OF 40 KDA ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 17 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of catabolic process#GO:0009895;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252;RNA stabilization#GO:0043489;regulation of RNA stability#GO:0043487 MONDO|Ensembl=ENSMODG00000015504.4|UniProtKB=F6VZQ7 F6VZQ7 ANKRD7 PTHR24147:SF53 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN 26 MONDO|Ensembl=ENSMODG00000011405.4|UniProtKB=F6S6H4 F6S6H4 DNAAF2 PTHR22997:SF3 PIH1 DOMAIN-CONTAINING PROTEIN 1 PROTEIN KINTOUN plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based transport#GO:0099111;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;localization#GO:0051179;cilium-dependent cell motility#GO:0060285;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;cell motility#GO:0048870;microtubule-based movement#GO:0007018 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000049586.1|UniProtKB=A0A5F8GA16 A0A5F8GA16 PTHR35680:SF1 NFAT ACTIVATION MOLECULE 1 NFAT ACTIVATION MOLECULE 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 calcium-mediated signaling#GO:0019722;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;intracellular signaling cassette#GO:0141124;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;antigen receptor-mediated signaling pathway#GO:0050851;cellular process#GO:0009987;B cell receptor signaling pathway#GO:0050853;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of immune response#GO:0050776;immune system process#GO:0002376;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;calcineurin-mediated signaling#GO:0097720;calcineurin-NFAT signaling cascade#GO:0033173 membrane microdomain#GO:0098857;membrane raft#GO:0045121;membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000004892.3|UniProtKB=F7C2E4 F7C2E4 TMED5 PTHR22811:SF41 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 5 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;macromolecule localization#GO:0033036;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;cellular component organization#GO:0016043;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179 intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783 membrane traffic protein#PC00150;vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000039622.1|UniProtKB=K7E0H1 K7E0H1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012624.4|UniProtKB=A0A5F8HLA5 A0A5F8HLA5 DICER1 PTHR14950:SF82 DICER-RELATED ENDORIBONUCLEASE DICER nucleic acid binding#GO:0003676;hydrolase activity#GO:0016787;RNA binding#GO:0003723;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;binding#GO:0005488;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521 regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cellular process#GO:0050794;pre-miRNA processing#GO:0031054;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell death#GO:0008219;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;gene expression#GO:0010467;apoptotic DNA fragmentation#GO:0006309;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;cellular component disassembly#GO:0022411;RNA metabolic process#GO:0016070;DNA catabolic process#GO:0006308;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;siRNA processing#GO:0030422;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000038690.1|UniProtKB=K7E6B8 K7E6B8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000000181.4|UniProtKB=A0A5F8G969 A0A5F8G969 TMEM9 PTHR13064:SF1 TRANSMEMBRANE PROTEIN 9 FAMILY MEMBER PROTON-TRANSPORTING V-TYPE ATPASE COMPLEX ASSEMBLY REGULATOR TMEM9 MONDO|Ensembl=ENSMODG00000020052.3|UniProtKB=F6ZGA6 F6ZGA6 LOC100617353 PTHR48018:SF133 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AL1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000000550.4|UniProtKB=F6XM16 F6XM16 ANGPTL5 PTHR19143:SF185 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 5 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000023389.2|UniProtKB=F6TQF2 F6TQF2 PTHR11792:SF20 ARRESTIN BETA-ARRESTIN-2 G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of ERK1 and ERK2 cascade#GO:0070372;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;negative regulation of signal transduction#GO:0009968;receptor internalization#GO:0031623;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;import into cell#GO:0098657;regulation of MAPK cascade#GO:0043408;endocytosis#GO:0006897;negative regulation of biological process#GO:0048519;sensory perception of pain#GO:0019233;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;nervous system process#GO:0050877;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;establishment of localization#GO:0051234;positive regulation of MAPK cascade#GO:0043410;receptor-mediated endocytosis#GO:0006898;system process#GO:0003008;negative regulation of cellular process#GO:0048523;positive regulation of intracellular signal transduction#GO:1902533;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;transport#GO:0006810;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;localization#GO:0051179;sensory perception#GO:0007600 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>beta-ARR2#P05923;CCKR signaling map#P06959>Beta-arrestin-1/2#P07187;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>beta-arrestin#P00723;Wnt signaling pathway#P00057>beta-arrestin#P01456;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>beta-arrestin#P00880 MONDO|Ensembl=ENSMODG00000012227.4|UniProtKB=A0A5F8GNM4 A0A5F8GNM4 PTHR10872:SF1 SH2B ADAPTER PROTEIN SH2B ADAPTER PROTEIN 3 receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;binding#GO:0005488;signaling receptor binding#GO:0005102 cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of response to cytokine stimulus#GO:0060759;response to chemokine#GO:1990868;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of response to stimulus#GO:0048585;response to cytokine#GO:0034097;response to chemical#GO:0042221;hemopoiesis#GO:0030097;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;G protein-coupled receptor signaling pathway#GO:0007186;anatomical structure development#GO:0048856;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;response to peptide#GO:1901652;intracellular signal transduction#GO:0035556;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;cellular response to chemokine#GO:1990869;negative regulation of response to cytokine stimulus#GO:0060761;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000003294.4|UniProtKB=F7EG06 F7EG06 SUCLG2 PTHR11815:SF18 SUCCINYL-COA SYNTHETASE BETA CHAIN SUCCINATE--COA LIGASE [GDP-FORMING] SUBUNIT BETA, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;tricarboxylic acid cycle#GO:0006099;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;energy derivation by oxidation of organic compounds#GO:0015980 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ligase#PC00142 MONDO|Ensembl=ENSMODG00000006036.5|UniProtKB=F6ZUD3 F6ZUD3 CPEB4 PTHR12566:SF2 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 4 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;translation factor activity#GO:0180051;translation regulator activity#GO:0045182;mRNA 3'-UTR binding#GO:0003730 post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of translation#GO:0017148;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 neuron projection#GO:0043005;nucleus#GO:0005634;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000005235.4|UniProtKB=F6ZCH3 F6ZCH3 ITGB6 PTHR10082:SF11 INTEGRIN BETA SUBUNIT INTEGRIN BETA-6 binding#GO:0005488;signaling receptor binding#GO:0005102;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877 cell surface receptor signaling pathway#GO:0007166;cell adhesion mediated by integrin#GO:0033627;cellular process#GO:0009987;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;cell migration#GO:0016477;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;membrane#GO:0016020;membrane protein complex#GO:0098796;cell-substrate junction#GO:0030055;plasma membrane#GO:0005886;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;signaling receptor complex#GO:0043235;anchoring junction#GO:0070161;integrin complex#GO:0008305;cell junction#GO:0030054 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 MONDO|Ensembl=ENSMODG00000003806.4|UniProtKB=A0A5F8GH66 A0A5F8GH66 SQSTM1 PTHR15090:SF0 SEQUESTOSOME 1-RELATED SEQUESTOSOME-1 K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;polyubiquitin modification-dependent protein binding#GO:0031593;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;modification-dependent protein binding#GO:0140030 autophagy#GO:0006914;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;macroautophagy#GO:0016236;catabolic process#GO:0009056;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;vesicle organization#GO:0016050;process utilizing autophagic mechanism#GO:0061919;endosome organization#GO:0007032;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;autophagosome#GO:0005776;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000024710.2|UniProtKB=F7AEG5 F7AEG5 PTHR11556:SF11 FRUCTOSE-1,6-BISPHOSPHATASE-RELATED FRUCTOSE-1,6-BISPHOSPHATASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;sugar-phosphatase activity#GO:0050308;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319;cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;carbohydrate biosynthetic process#GO:0016051;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;glucose metabolic process#GO:0006006 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 phosphatase#PC00181;carbohydrate phosphatase#PC00066;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000049171.1|UniProtKB=A0A5F8G4M6 A0A5F8G4M6 MIS18A PTHR16431:SF2 NEUROGENIC PROTEIN MASTERMIND PROTEIN MIS18-ALPHA chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;kinetochore organization#GO:0051383;cellular component organization or biogenesis#GO:0071840;kinetochore assembly#GO:0051382;organelle assembly#GO:0070925;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 MONDO|Ensembl=ENSMODG00000008888.4|UniProtKB=A0A5F8H4J4 A0A5F8H4J4 METAP1D PTHR43330:SF28 METHIONINE AMINOPEPTIDASE METHIONINE AMINOPEPTIDASE 1D, MITOCHONDRIAL metalloexopeptidase activity#GO:0008235;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;exopeptidase activity#GO:0008238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000015714.2|UniProtKB=F7BSB6 F7BSB6 TCF23 PTHR23349:SF58 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 23 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000017934.4|UniProtKB=F6TRX9 F6TRX9 METTL24 PTHR32026:SF10 METHYLTRANSFERASE-LIKE PROTEIN 24 METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED methyltransferase#PC00155;transferase#PC00220 MONDO|Ensembl=ENSMODG00000013323.3|UniProtKB=F7GJF7 F7GJF7 CINP PTHR15827:SF2 CYCLIN-DEPENDENT KINASE 2-INTERACTING PROTEIN CYCLIN-DEPENDENT KINASE 2-INTERACTING PROTEIN DNA replication#GO:0006260;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Cell cycle#P00013>Cdk2#P00485 MONDO|Ensembl=ENSMODG00000009932.3|UniProtKB=F6R8K7 F6R8K7 CSGALNACT1 PTHR12369:SF19 CHONDROITIN SYNTHASE CHONDROITIN SULFATE N-ACETYLGALACTOSAMINYLTRANSFERASE 1 acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000013620.4|UniProtKB=F6VE57 F6VE57 PTHR24278:SF30 COAGULATION FACTOR TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 2 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000020568.4|UniProtKB=P50103 P50103 UCHL1 PTHR10589:SF19 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L1 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 Parkinson disease#P00049>UCH-L1#P01210 MONDO|Ensembl=ENSMODG00000006594.4|UniProtKB=F7AKA6 F7AKA6 MAP3K4 PTHR48016:SF32 MAP KINASE KINASE KINASE SSK2-RELATED-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 4 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;p38MAPK cascade#GO:0038066;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Oxidative stress response#P00046>MKK4#P01138;p38 MAPK pathway#P05918>MEKK4#P06026;FGF signaling pathway#P00021>MEKK1-5#P00634;Integrin signalling pathway#P00034>ERK#P00907;Interleukin signaling pathway#P00036>MEK#P00984;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MEK#P00864;Ras Pathway#P04393>MEKK1/4#P04543;PDGF signaling pathway#P00047>ERK#P01143;EGF receptor signaling pathway#P00018>MEKK1-5#P00553 MONDO|Ensembl=ENSMODG00000016605.3|UniProtKB=F6ZCW3 F6ZCW3 PTHR12448:SF0 ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL ATP SYNTHASE F(1) COMPLEX SUBUNIT EPSILON, MITOCHONDRIAL channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;proton channel activity#GO:0015252;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000004149.5|UniProtKB=F7FLG6 F7FLG6 ONECUT3 PTHR14057:SF34 TRANSCRIPTION FACTOR ONECUT ONE CUT DOMAIN FAMILY MEMBER 3 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000006826.5|UniProtKB=F6PG76 F6PG76 GALNT17 PTHR11675:SF38 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 17 acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000008301.4|UniProtKB=F6SEJ6 F6SEJ6 SCAF8 PTHR15921:SF7 PRE-MRNA CLEAVAGE COMPLEX II SR-RELATED AND CTD-ASSOCIATED FACTOR 8 RNA polymerase core enzyme binding#GO:0043175;RNA polymerase binding#GO:0070063;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA binding#GO:0003723;enzyme binding#GO:0019899;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 macromolecule metabolic process#GO:0043170;termination of RNA polymerase II transcription#GO:0006369;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription termination#GO:0006353;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000044795.1|UniProtKB=A0A5F8G4H4 A0A5F8G4H4 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018807.4|UniProtKB=F6ZMA2 F6ZMA2 HORMAD1 PTHR48225:SF1 HORMA DOMAIN-CONTAINING PROTEIN 1 HORMA DOMAIN-CONTAINING PROTEIN 1 chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;negative regulation of cell cycle#GO:0045786;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;homologous chromosome pairing at meiosis#GO:0007129;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;cellular component assembly#GO:0022607;synaptonemal complex assembly#GO:0007130;nuclear division#GO:0000280;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;negative regulation of cell cycle phase transition#GO:1901988;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;biological regulation#GO:0065007;regulation of reproductive process#GO:2000241;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;intracellular signal transduction#GO:0035556;organelle fission#GO:0048285;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;reproductive process#GO:0022414;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;synaptonemal structure#GO:0099086;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793 MONDO|Ensembl=ENSMODG00000001724.4|UniProtKB=F6XG85 F6XG85 TBC1D8 PTHR22957:SF260 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 8 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000005475.4|UniProtKB=F7CG22 F7CG22 NGB PTHR46458:SF1 BLR2807 PROTEIN NEUROGLOBIN small molecule binding#GO:0036094;binding#GO:0005488;molecular carrier activity#GO:0140104 transport#GO:0006810;response to hypoxia#GO:0001666;establishment of localization#GO:0051234;localization#GO:0051179;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;response to stimulus#GO:0050896 transporter#PC00227 MONDO|Ensembl=ENSMODG00000011517.4|UniProtKB=A0A5F8H2E6 A0A5F8H2E6 MORF4L1 PTHR10880:SF48 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;chromatin#GO:0000785;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000004482.5|UniProtKB=F6VRH1 F6VRH1 DGKQ PTHR11255:SF125 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE THETA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 membrane#GO:0016020;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;kinase#PC00137 MONDO|Ensembl=ENSMODG00000042968.1|UniProtKB=A0A5F8H4I4 A0A5F8H4I4 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000011601.4|UniProtKB=A0A5F8G2H8 A0A5F8G2H8 GLYCTK PTHR12227:SF0 GLYCERATE KINASE GLYCERATE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 carbohydrate kinase#PC00065 MONDO|Ensembl=ENSMODG00000047908.1|UniProtKB=F7DCZ7 F7DCZ7 LOC100016034 PTHR48018:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 974 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003057.4|UniProtKB=A0A5F8HJJ7 A0A5F8HJJ7 PTHR24376:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 850 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000013824.5|UniProtKB=F6SEX1 F6SEX1 STX1A PTHR19957:SF84 SYNTAXIN SYNTAXIN-1A SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein transport#GO:0015031;secretion by cell#GO:0032940;cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179;cellular component organization#GO:0016043;export from cell#GO:0140352;vesicle fusion#GO:0006906;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;exocytosis#GO:0006887;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284 plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091 MONDO|Ensembl=ENSMODG00000037852.1|UniProtKB=A0A5F8H4P4 A0A5F8H4P4 MRPL58 PTHR11075:SF54 PEPTIDE CHAIN RELEASE FACTOR LARGE RIBOSOMAL SUBUNIT PROTEIN ML62 catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;translation factor activity#GO:0180051;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;carboxylic ester hydrolase activity#GO:0052689 translation release factor#PC00225 MONDO|Ensembl=ENSMODG00000048900.1|UniProtKB=A0A5F8GWH7 A0A5F8GWH7 LOC103094333 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000042085.1|UniProtKB=A0A5F8H2J6 A0A5F8H2J6 MAVS PTHR21446:SF6 DUF3504 DOMAIN-CONTAINING PROTEIN MITOCHONDRIAL ANTIVIRAL-SIGNALING PROTEIN MONDO|Ensembl=ENSMODG00000006221.3|UniProtKB=F7FS92 F7FS92 CD93 PTHR24050:SF25 PA14 DOMAIN-CONTAINING PROTEIN CD93 MOLECULE MONDO|Ensembl=ENSMODG00000021282.4|UniProtKB=F7GEA2 F7GEA2 PTHR23024:SF239 ARYLACETAMIDE DEACETYLASE AADACL2 FAMILY MEMBER 2 membrane#GO:0016020;cellular anatomical structure#GO:0110165 deacetylase#PC00087 MONDO|Ensembl=ENSMODG00000020628.4|UniProtKB=A0A5F8HFD0 A0A5F8HFD0 TEC PTHR24418:SF219 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE TEC protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 MONDO|Ensembl=ENSMODG00000016832.5|UniProtKB=F6R2K2 F6R2K2 DIDO1 PTHR11477:SF13 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN DEATH-INDUCER OBLITERATOR 1 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000002646.4|UniProtKB=F7DIC7 F7DIC7 CHRND PTHR18945:SF61 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT DELTA monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;acetylcholine receptor signaling pathway#GO:0095500;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;synaptic transmission, cholinergic#GO:0007271;transport#GO:0006810;muscle contraction#GO:0006936;system process#GO:0003008;establishment of localization#GO:0051234;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;membrane depolarization#GO:0051899;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;neuromuscular process#GO:0050905;trans-synaptic signaling#GO:0099537;response to nitrogen compound#GO:1901698;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;synaptic signaling#GO:0099536;response to chemical#GO:0042221;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;muscle system process#GO:0003012;regulation of biological process#GO:0050789;signaling#GO:0023052;skeletal muscle contraction#GO:0003009;response to stimulus#GO:0050896;nervous system process#GO:0050877;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085 organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>delta#P01092;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 MONDO|Ensembl=ENSMODG00000010620.4|UniProtKB=F7CNA5 F7CNA5 TACC1 PTHR13924:SF12 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 1 binding#GO:0005488;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515 cell cycle#GO:0007049;cellular component organization#GO:0016043;nuclear migration#GO:0007097;cell cycle process#GO:0022402;cell differentiation#GO:0030154;establishment of organelle localization#GO:0051656;cytoplasmic microtubule organization#GO:0031122;animal gross anatomical part developmental process#GO:0160108;organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;cellular localization#GO:0051641;system development#GO:0048731;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;intracellular transport#GO:0046907;developmental process#GO:0032502;transport#GO:0006810;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;microtubule-based process#GO:0007017 microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;spindle pole#GO:0000922;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000049384.1|UniProtKB=A0A5F8GVH7 A0A5F8GVH7 PTHR11003:SF330 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM TWO PORE DOMAIN CHANNEL SUBFAMILY K MEMBER 4 monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000025408.3|UniProtKB=A0A5F8HFA2 A0A5F8HFA2 TXNDC12 PTHR15337:SF10 ANTERIOR GRADIENT PROTEIN-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 12 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 reductase#PC00198;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000007707.5|UniProtKB=F7EVI4 F7EVI4 BLVRB PTHR43355:SF2 FLAVIN REDUCTASE (NADPH) FLAVIN REDUCTASE (NADPH) oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198 MONDO|Ensembl=ENSMODG00000008890.4|UniProtKB=F7BRH7 F7BRH7 LOC100021845 PTHR26452:SF246 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000037812.1|UniProtKB=A0A5F8GVR5 A0A5F8GVR5 PTHR41694:SF3 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 10 POL PROTEIN-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000050004.1|UniProtKB=A0A5F8GUB9 A0A5F8GUB9 APOBR PTHR15964:SF0 APOLIPOPROTEIN B48 RECEPTOR APOLIPOPROTEIN B RECEPTOR cargo receptor activity#GO:0038024 primary metabolic process#GO:0044238;cellular process#GO:0009987;glycerolipid metabolic process#GO:0046486;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;neutral lipid metabolic process#GO:0006638 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000039251.1|UniProtKB=A0A5F8GZB4 A0A5F8GZB4 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000023312.2|UniProtKB=F6RSM4 F6RSM4 TAAR1 PTHR24249:SF415 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 1 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000855.4|UniProtKB=A0A5F8GMH9 A0A5F8GMH9 KLHL12 PTHR24412:SF494 KELCH PROTEIN KELCH-LIKE PROTEIN 12 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 membrane organization#GO:0061024;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;intracellular transport#GO:0046907;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;ubiquitin-dependent protein catabolic process#GO:0006511;vesicle budding from membrane#GO:0006900;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;COPII-coated vesicle budding#GO:0090114;localization#GO:0051179;protein metabolic process#GO:0019538;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;cellular localization#GO:0051641 Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;COPII-coated ER to Golgi transport vesicle#GO:0030134;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular vesicle#GO:0097708;vesicle#GO:0031982 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000038941.1|UniProtKB=A0A5F8H5U9 A0A5F8H5U9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000004683.3|UniProtKB=F6RRG4 F6RRG4 LOC100023972 PTHR12398:SF20 PROTEIN PHOSPHATASE INHIBITOR PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 2 enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 phosphatase inhibitor#PC00183 MONDO|Ensembl=ENSMODG00000047450.1|UniProtKB=A0A5F8GLB0 A0A5F8GLB0 LOC100028726 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005864.4|UniProtKB=F6T425 F6T425 AZIN1 PTHR11482:SF7 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ANTIZYME INHIBITOR 1 molecular function regulator activity#GO:0098772;carbon-carbon lyase activity#GO:0016830;enzyme activator activity#GO:0008047;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;ornithine decarboxylase activity#GO:0004586;molecular function activator activity#GO:0140677;lyase activity#GO:0016829;enzyme regulator activity#GO:0030234 biogenic amine metabolic process#GO:0006576;biological regulation#GO:0065007;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596;negative regulation of protein catabolic process#GO:0042177;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;amine metabolic process#GO:0009308;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;polyamine metabolic process#GO:0006595;regulation of transmembrane transport#GO:0034762;negative regulation of biological process#GO:0048519;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 MONDO|Ensembl=ENSMODG00000017858.4|UniProtKB=F6YIN6 F6YIN6 UBR1 PTHR21497:SF27 UBIQUITIN LIGASE E3 ALPHA-RELATED E3 UBIQUITIN-PROTEIN LIGASE UBR1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 MONDO|Gene=TCP1|UniProtKB=Q9XT06 Q9XT06 TCP1 PTHR11353:SF84 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ALPHA protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;protein folding chaperone complex#GO:0101031;chaperonin-containing T-complex#GO:0005832;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 chaperonin#PC00073 MONDO|Ensembl=ENSMODG00000008650.3|UniProtKB=F6VF81 F6VF81 PTHR11214:SF87 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 8 catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 aminoglycan biosynthetic process#GO:0006023;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000024952.2|UniProtKB=F6UTP9 F6UTP9 RRS1 PTHR17602:SF4 RIBOSOME BIOGENESIS REGULATORY PROTEIN RIBOSOME BIOGENESIS REGULATORY PROTEIN HOMOLOG RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000011981.3|UniProtKB=F7B9L2 F7B9L2 LOC100618208 PTHR45880:SF1 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2 snRNP#GO:0005686;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000009021.5|UniProtKB=F7B348 F7B348 CDX2 PTHR24332:SF27 HOMEOBOX PROTEIN CDX HOMEOBOX PROTEIN CDX-2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;anterior/posterior axis specification#GO:0009948;regulation of gene expression#GO:0010468;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;tube development#GO:0035295;regulation of primary metabolic process#GO:0080090;embryonic pattern specification#GO:0009880;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;pattern specification process#GO:0007389;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000013346.3|UniProtKB=F7GA76 F7GA76 PTHR31759:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 167 COILED-COIL DOMAIN-CONTAINING PROTEIN 167 MONDO|Ensembl=ENSMODG00000023884.1|UniProtKB=F7FMI7 F7FMI7 ACTL9 PTHR11937:SF194 ACTIN ACTIN-LIKE PROTEIN 9 structural molecule activity#GO:0005198;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;structural constituent of cytoskeleton#GO:0005200;kinase binding#GO:0019900;binding#GO:0005488;structural constituent of synapse#GO:0098918;protein binding#GO:0005515 anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;axon development#GO:0061564;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;supramolecular complex#GO:0099080;chromatin#GO:0000785;neuron projection#GO:0043005;histone acetyltransferase complex#GO:0000123;cell junction#GO:0030054;actin filament#GO:0005884;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;acetyltransferase complex#GO:1902493;supramolecular fiber#GO:0099512;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;H4 histone acetyltransferase complex#GO:1902562;membrane#GO:0016020;intracellular protein-containing complex#GO:0140535;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;transferase complex#GO:1990234;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;axon#GO:0030424;catalytic complex#GO:1902494 actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000018099.3|UniProtKB=F7FFQ9 F7FFQ9 LPAR5 PTHR24234:SF6 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 5 response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;response to stress#GO:0006950 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000023662.1|UniProtKB=F6R4U7 F6R4U7 POP7 PTHR15314:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P20 RIBONUCLEASE P PROTEIN SUBUNIT P20 RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031;endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000011045.4|UniProtKB=A0A5F8G706 A0A5F8G706 WNT3 PTHR12027:SF82 WNT RELATED PROTO-ONCOGENE WNT-3 protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell fate commitment#GO:0045165;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;signaling#GO:0023052 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 MONDO|Ensembl=ENSMODG00000012801.3|UniProtKB=F7DZ78 F7DZ78 NFKBIA PTHR46680:SF1 NF-KAPPA-B INHIBITOR ALPHA NF-KAPPA-B INHIBITOR ALPHA transcription factor binding#GO:0008134;binding#GO:0005488;molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297 regulation of canonical NF-kappaB signal transduction#GO:0043122;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 T cell activation#P00053>I kappa B#P01323;B cell activation#P00010>I kappa B#P00392;Apoptosis signaling pathway#P00006>IkappaB#P00292;CCKR signaling map#P06959>IKBalpha#P07053;Toll receptor signaling pathway#P00054>IkappaB#P01338;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IkappaB#P00857 MONDO|Ensembl=ENSMODG00000041804.1|UniProtKB=A0A5F8GJ45 A0A5F8GJ45 PTHR45737:SF6 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A MONDO|Ensembl=ENSMODG00000005961.3|UniProtKB=A0A5F8GWV9 A0A5F8GWV9 PTHR11246:SF3 PRE-MRNA SPLICING FACTOR CROOKED NECK-LIKE PROTEIN 1 protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;post-mRNA release spliceosomal complex#GO:0071014;nucleus#GO:0005634;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000000933.4|UniProtKB=F7F802 F7F802 MMD2 PTHR20855:SF107 ADIPOR/PROGESTIN RECEPTOR-RELATED MONOCYTE TO MACROPHAGE DIFFERENTIATION FACTOR 2 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000044127.1|UniProtKB=A0A5F8GM19 A0A5F8GM19 TMEM222 PTHR20921:SF0 TRANSMEMBRANE PROTEIN 222 TRANSMEMBRANE PROTEIN 222 MONDO|Ensembl=ENSMODG00000000887.4|UniProtKB=F7BIT1 F7BIT1 LOC100010619 PTHR24264:SF15 TRYPSIN-RELATED TRYPSIN catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000014521.4|UniProtKB=F7F3K8 F7F3K8 ARHGAP20 PTHR23179:SF28 T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED RHO GTPASE-ACTIVATING PROTEIN 20 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000016576.4|UniProtKB=F7D3E0 F7D3E0 LOC107649624 PTHR24256:SF574 TRYPTASE-RELATED INACTIVE SERINE PROTEASE 39-RELATED serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000049702.1|UniProtKB=A0A5F8GWY9 A0A5F8GWY9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000044168.1|UniProtKB=A0A5F8H858 A0A5F8H858 TMEM70 PTHR13281:SF0 TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615 mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000028178.2|UniProtKB=K7E1G3 K7E1G3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009638.4|UniProtKB=F6QTX3 F6QTX3 CBY1 PTHR21533:SF20 LEUCINE-RICH PROTEIN PROTEIN CHIBBY HOMOLOG 1 regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000050814.1|UniProtKB=K7E0S5 K7E0S5 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000048814.1|UniProtKB=A0A5F8G2K3 A0A5F8G2K3 PTHR24390:SF139 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 48 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000003990.4|UniProtKB=F7DSE4 F7DSE4 NFX1 PTHR12360:SF16 NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1 TRANSCRIPTIONAL REPRESSOR NF-X1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000009352.5|UniProtKB=A0A5F8G4R4 A0A5F8G4R4 TLE1 PTHR10814:SF29 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of cell communication#GO:0010648;regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 MONDO|Ensembl=ENSMODG00000004363.3|UniProtKB=H9H651 H9H651 FUT1 PTHR11927:SF9 GALACTOSIDE 2-L-FUCOSYLTRANSFERASE L-FUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000005614.3|UniProtKB=A0A5F8H774 A0A5F8H774 CNN2 PTHR47385:SF7 CALPONIN CALPONIN-2 cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000050313.1|UniProtKB=A0A5F8GDN2 A0A5F8GDN2 PTHR14519:SF8 VITAMIN K EPOXIDE REDUCTASE COMPLEX, SUBUNIT 1 VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 response to wounding#GO:0009611;response to stress#GO:0006950;ketone metabolic process#GO:0042180;hemostasis#GO:0007599;vitamin K metabolic process#GO:0042373;coagulation#GO:0050817;cellular process#GO:0009987;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;regulation of body fluid levels#GO:0050878;biological regulation#GO:0065007;metabolic process#GO:0008152;wound healing#GO:0042060;blood coagulation#GO:0007596;regulation of biological quality#GO:0065008 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000009776.5|UniProtKB=F6TF48 F6TF48 SLITRK5 PTHR45773:SF5 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 5 regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell junction assembly#GO:1901888;system development#GO:0048731;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;neuron projection morphogenesis#GO:0048812;positive regulation of synapse assembly#GO:0051965;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;regulation of synapse organization#GO:0050807;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;positive regulation of cellular component biogenesis#GO:0044089;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009310.4|UniProtKB=F7GJZ7 F7GJZ7 CSK PTHR24418:SF472 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE CSK transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096;non-membrane spanning protein tyrosine kinase activity#GO:0004715;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of immune system process#GO:0002682;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular component organization#GO:0016043;adherens junction organization#GO:0034332;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;cell-cell junction organization#GO:0045216 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 CCKR signaling map#P06959>CSK#P07072;T cell activation#P00053>Csk#P01304;Parkinson disease#P00049>Src kinase#P01230;Integrin signalling pathway#P00034>Csk#P00913 MONDO|Ensembl=ENSMODG00000039490.1|UniProtKB=A0A5F8HCQ4 A0A5F8HCQ4 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000023147.3|UniProtKB=F7DW41 F7DW41 LOC100033201 PTHR24377:SF908 IP01015P-RELATED ZINC FINGER PROTEIN 514 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017076.4|UniProtKB=F6VKU2 F6VKU2 MYT1 PTHR10816:SF10 MYELIN TRANSCRIPTION FACTOR 1-RELATED MYELIN TRANSCRIPTION FACTOR 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000024000.2|UniProtKB=A0A5F8G589 A0A5F8G589 LOC100017632 PTHR13976:SF60 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007 organelle#GO:0043226;nucleoplasm#GO:0005654;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000005041.4|UniProtKB=A0A5F8HBN3 A0A5F8HBN3 ELAVL1 PTHR10352:SF13 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 1 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of RNA catabolic process#GO:1902369;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 CCKR signaling map#P06959>HuR#G07273;CCKR signaling map#P06959>HuR#P07211;CCKR signaling map#P06959>HuR#G06980 MONDO|Ensembl=ENSMODG00000001535.3|UniProtKB=F7EMU7 F7EMU7 MSX1 PTHR24338:SF8 HOMEOBOX PROTEIN MSX HOMEOBOX PROTEIN MSX-1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000007545.5|UniProtKB=F7GAM2 F7GAM2 TESK1 PTHR46485:SF3 LIM DOMAIN KINASE 1 DUAL SPECIFICITY TESTIS-SPECIFIC PROTEIN KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 positive regulation of cellular component organization#GO:0051130;actin filament-based process#GO:0030029;positive regulation of organelle organization#GO:0010638;regulation of actin filament bundle assembly#GO:0032231;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;positive regulation of actin filament bundle assembly#GO:0032233;organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000014254.5|UniProtKB=F6XJP9 F6XJP9 TAMALIN PTHR15963:SF3 GENERAL RECEPTOR FOR PHOSPHOINOSITIDES 1-ASSOCIATED SCAFFOLD PROTEIN-RELATED PROTEIN TAMALIN regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of endocytosis#GO:0030100;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological quality#GO:0065008;cell communication#GO:0007154;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627 plasma membrane#GO:0005886;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000013424.5|UniProtKB=F7C537 F7C537 EIF5 PTHR23001:SF7 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 5 enzyme regulator activity#GO:0030234;protein binding#GO:0005515;binding#GO:0005488;translation initiation factor binding#GO:0031369;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000012807.3|UniProtKB=F7DYR4 F7DYR4 PSMA6 PTHR11599:SF11 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 proteasome complex#GO:0000502;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 MONDO|Ensembl=ENSMODG00000016760.4|UniProtKB=A0A5F8GPB6 A0A5F8GPB6 METRN PTHR28593:SF2 METEORIN-LIKE PROTEIN METEORIN receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;positive regulation of cell projection organization#GO:0031346;system development#GO:0048731;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of cell projection organization#GO:0031344;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;positive regulation of axonogenesis#GO:0050772;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;positive regulation of cell development#GO:0010720;positive regulation of cell differentiation#GO:0045597;regulation of axonogenesis#GO:0050770;gliogenesis#GO:0042063;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000027415.1|UniProtKB=K7E6E7 K7E6E7 LOC100017586 PTHR11937:SF465 ACTIN ACTIN RELATED PROTEIN T2 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000051498.1|UniProtKB=A0A5F8H3W4 A0A5F8H3W4 PTHR23235:SF133 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000017253.4|UniProtKB=A0A5F8GJH2 A0A5F8GJH2 TPM3 PTHR19269:SF38 TROPOMYOSIN TROPOMYOSIN ALPHA-3 CHAIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779 muscle system process#GO:0003012;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;multicellular organismal process#GO:0032501;muscle contraction#GO:0006936;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;system process#GO:0003008;cellular component organization or biogenesis#GO:0071840 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;actin filament#GO:0005884;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 actin binding motor protein#PC00040 MONDO|Ensembl=ENSMODG00000017146.5|UniProtKB=F6ZTE5 F6ZTE5 PBXIP1 PTHR28638:SF1 CELL CYCLE PROGRESSION PROTEIN 1 PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR-INTERACTING PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000025529.3|UniProtKB=F6V226 F6V226 MGST2 PTHR10250:SF13 MICROSOMAL GLUTATHIONE S-TRANSFERASE MICROSOMAL GLUTATHIONE S-TRANSFERASE 2 glutathione transferase activity#GO:0004364;carbon-sulfur lyase activity#GO:0016846;lyase activity#GO:0016829;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;transferase activity#GO:0016740;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;icosanoid metabolic process#GO:0006690;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;icosanoid biosynthetic process#GO:0046456;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle envelope#GO:0031967 transferase#PC00220 MONDO|Ensembl=ENSMODG00000015290.2|UniProtKB=F6T6L3 F6T6L3 MTURN PTHR32008:SF2 MATURIN MATURIN positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of myeloid cell differentiation#GO:0045639;regulation of cell development#GO:0060284;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of developmental process#GO:0050793;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of myeloid cell differentiation#GO:0045637;regulation of hemopoiesis#GO:1903706 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000009658.5|UniProtKB=F6Q881 F6Q881 SPTB PTHR11915:SF248 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, ERYTHROCYTIC protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000021184.2|UniProtKB=H9H7W8 H9H7W8 BET1L PTHR12791:SF37 GOLGI SNARE BET1-RELATED BET1-LIKE PROTEIN SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 localization#GO:0051179;cellular localization#GO:0051641;regulation of cellular process#GO:0050794;cytosolic transport#GO:0016482;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;establishment of localization#GO:0051234;regulation of transport#GO:0051049;endosomal transport#GO:0016197;regulation of localization#GO:0032879;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 membrane#GO:0016020;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201 SNARE protein#PC00034 MONDO|Ensembl=ENSMODG00000048050.1|UniProtKB=A0A5F8H479 A0A5F8H479 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000027370.2|UniProtKB=K7E0K6 K7E0K6 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000011995.5|UniProtKB=F7B931 F7B931 CTDP1 PTHR23081:SF36 RNA POLYMERASE II CTD PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Transcription regulation by bZIP transcription factor#P00055>TFIIF#P01394;General transcription regulation#P00023>TFIIF#P00665 MONDO|Ensembl=ENSMODG00000018427.3|UniProtKB=F6XU08 F6XU08 TFRC PTHR10404:SF26 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE TRANSFERRIN RECEPTOR PROTEIN 1 catalytic activity#GO:0003824;peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000006348.4|UniProtKB=F6ZS53 F6ZS53 EFCAB9 PTHR47065:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 9 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 9 molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 cell motility#GO:0048870;microtubule-based movement#GO:0007018;gamete generation#GO:0007276;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;sperm motility#GO:0097722;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;anatomical structure development#GO:0048856;cilium-dependent cell motility#GO:0060285;multicellular organismal reproductive process#GO:0048609;spermatid differentiation#GO:0048515;spermatid development#GO:0007286;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;sexual reproduction#GO:0019953;male gamete generation#GO:0048232;developmental maturation#GO:0021700;sperm capacitation#GO:0048240;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;cellular developmental process#GO:0048869;cell maturation#GO:0048469;microtubule-based process#GO:0007017;flagellated sperm motility#GO:0030317;spermatogenesis#GO:0007283;developmental process#GO:0032502 9+2 motile cilium#GO:0097729;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sperm principal piece#GO:0097228;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000019449.4|UniProtKB=F6RXI0 F6RXI0 BLM PTHR13710:SF163 DNA HELICASE RECQ FAMILY MEMBER RECQ-LIKE DNA HELICASE BLM catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;DNA helicase activity#GO:0003678;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;telomere organization#GO:0032200;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DNA helicase#PC00011;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000017088.3|UniProtKB=F6V450 F6V450 GNAT3 PTHR10218:SF66 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-3 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 cell communication#GO:0007154;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;cellular response to stimulus#GO:0051716;sensory perception of bitter taste#GO:0050913;regulation of biological process#GO:0050789;system process#GO:0003008;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;catalytic complex#GO:1902494;cilium#GO:0005929;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;photoreceptor inner segment#GO:0001917;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020 heterotrimeric G-protein#PC00117;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000007780.4|UniProtKB=F7AWB1 F7AWB1 PTHR43294:SF1 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 2 monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;primary active transmembrane transporter activity#GO:0015399;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;inorganic ion homeostasis#GO:0098771;localization#GO:0051179;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;export from cell#GO:0140352;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000018121.4|UniProtKB=F7F1T5 F7F1T5 FBXL4 PTHR13318:SF152 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 4 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000049144.1|UniProtKB=A0A5F8G2X2 A0A5F8G2X2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000017522.4|UniProtKB=F7EI89 F7EI89 SLC18B1 PTHR23506:SF44 GH10249P MFS-TYPE TRANSPORTER SLC18B1 monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic cation transmembrane transporter activity#GO:0008324 organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;presynapse#GO:0098793;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000041740.1|UniProtKB=A0A5F8H9L3 A0A5F8H9L3 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004859.5|UniProtKB=F6TP06 F6TP06 ARHGAP32 PTHR15729:SF13 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 32 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of synapse assembly#GO:0051963;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cellular response to stimulus#GO:0051716;regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;regulation of synapse structure or activity#GO:0050803;cell communication#GO:0007154;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;regulation of dendritic spine morphogenesis#GO:0061001 cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;glutamatergic synapse#GO:0098978;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;postsynapse#GO:0098794;cell junction#GO:0030054;postsynaptic density#GO:0014069 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 Gonadotropin-releasing hormone receptor pathway#P06664>RICS#G06882;Gonadotropin-releasing hormone receptor pathway#P06664>RICS#P06765;Gonadotropin-releasing hormone receptor pathway#P06664>RICS#G06669 MONDO|Ensembl=ENSMODG00000010385.3|UniProtKB=F7AV76 F7AV76 TEX47 PTHR34035:SF1 TESTIS-EXPRESSED PROTEIN 47 TESTIS-EXPRESSED PROTEIN 47 MONDO|Ensembl=ENSMODG00000047833.1|UniProtKB=A0A5F8GAR8 A0A5F8GAR8 IGSF21 PTHR23277:SF121 NECTIN-RELATED IMMUNOGLOBULIN SUPERFAMILY MEMBER 21 protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631 regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of signaling#GO:0023051;cell adhesion#GO:0007155;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;homophilic cell-cell adhesion#GO:0007156 synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;anchoring junction#GO:0070161;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;cell junction#GO:0030054;adherens junction#GO:0005912;synaptic membrane#GO:0097060 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000007537.3|UniProtKB=A0A5F8GRB1 A0A5F8GRB1 PTHR45752:SF50 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1 defense response to other organism#GO:0098542;biological regulation#GO:0065007;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to external biotic stimulus#GO:0043207;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;immune system process#GO:0002376;inflammatory response#GO:0006954 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000029638.2|UniProtKB=K7E1P6 K7E1P6 PTHR33166:SF1 GAG_P30 DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000042429.1|UniProtKB=A0A5F8GEM3 A0A5F8GEM3 PTHR20859:SF51 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-22 RECEPTOR SUBUNIT ALPHA-2 cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005757.3|UniProtKB=F6QDS6 F6QDS6 CTCF PTHR24388:SF46 ZINC FINGER PROTEIN TRANSCRIPTIONAL REPRESSOR CTCF sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008463.4|UniProtKB=F7GET1 F7GET1 RGS17 PTHR10845:SF196 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 17 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833 MONDO|Ensembl=ENSMODG00000004125.4|UniProtKB=F6UWH4 F6UWH4 MBD3 PTHR12396:SF12 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN PROTEIN 3 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;constitutive heterochromatin formation#GO:0140719;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519 intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000025681.3|UniProtKB=F6U085 F6U085 PTHR11771:SF216 LIPOXYGENASE ARACHIDONATE 12-LIPOXYGENASE, 12S-TYPE-LIKE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;icosanoid metabolic process#GO:0006690;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;arachidonate metabolic process#GO:0019369;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;lipid oxidation#GO:0034440 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000003623.3|UniProtKB=A0A5F8GAC8 A0A5F8GAC8 PTHR13464:SF0 TRANSCRIPTIONAL REGULATOR PROTEIN HCNGP SAP30-BINDING PROTEIN intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000016814.3|UniProtKB=F7FV92 F7FV92 PTHR24377:SF980 IP01015P-RELATED ZINC FINGER PROTEIN 420 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016627.4|UniProtKB=A0A5F8GM85 A0A5F8GM85 NPRL3 PTHR13153:SF5 CGTHBA PROTEIN -14 GENE PROTEIN GATOR1 COMPLEX PROTEIN NPRL3 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;negative regulation of TORC1 signaling#GO:1904262;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531 Seh1-associated complex#GO:0035859;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000003390.2|UniProtKB=F6TCE0 F6TCE0 METTL18 PTHR14614:SF177 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170 regulation of biological process#GO:0050789;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000006840.4|UniProtKB=A0A5F8H906 A0A5F8H906 MATN2 PTHR24020:SF35 COLLAGEN ALPHA MATRILIN-2 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000006612.3|UniProtKB=F7GEW5 F7GEW5 ZC3H6 PTHR13119:SF22 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 6 transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription repressor activity#GO:0001217 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription elongation#GO:0032784;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000010262.4|UniProtKB=F6VQ12 F6VQ12 ACSL5 PTHR43272:SF112 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 5 ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;regulation of localization#GO:0032879;regulation of transport#GO:0051049;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522;organophosphate metabolic process#GO:0019637;positive regulation of cellular process#GO:0048522;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;nucleoside phosphate biosynthetic process#GO:1901293;acyl-CoA metabolic process#GO:0006637;regulation of transmembrane transport#GO:0034762;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407 membrane#GO:0016020;mitochondrion#GO:0005739;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ligase#PC00142 MONDO|Ensembl=ENSMODG00000020738.4|UniProtKB=F7AN64 F7AN64 NUDT9 PTHR13030:SF8 NUDIX HYDROLASE ADP-RIBOSE PYROPHOSPHATASE hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000010004.4|UniProtKB=F6UAW0 F6UAW0 PTHR11819:SF112 SOLUTE CARRIER FAMILY 5 GLUCOSE SENSOR PROTEIN SLC5A4-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 import across plasma membrane#GO:0098739;multicellular organismal process#GO:0032501;carbohydrate transmembrane transport#GO:0034219;D-glucose transmembrane transport#GO:1904659;renal system process#GO:0003014;cellular process#GO:0009987;system process#GO:0003008;renal absorption#GO:0070293;localization#GO:0051179;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;carbohydrate transport#GO:0008643;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000005290.4|UniProtKB=F7E6M5 F7E6M5 CIRBP PTHR48034:SF5 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED COLD-INDUCIBLE RNA-BINDING PROTEIN mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000007747.4|UniProtKB=F7BJU3 F7BJU3 SAT1 PTHR10545:SF36 DIAMINE N-ACETYLTRANSFERASE DIAMINE ACETYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;ion binding#GO:0043167;acetyltransferase activity#GO:0016407;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169 transferase#PC00220;acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000040520.1|UniProtKB=A0A5F8G674 A0A5F8G674 LOC100025209 PTHR24377:SF980 IP01015P-RELATED ZINC FINGER PROTEIN 420 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000027889.2|UniProtKB=K7DZZ6 K7DZZ6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000012797.4|UniProtKB=F7EFT1 F7EFT1 CCND3 PTHR10177:SF65 CYCLINS G1_S-SPECIFIC CYCLIN-D3 kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cell cycle process#GO:0022402;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;regulation of G1/S transition of mitotic cell cycle#GO:2000045;mitotic cell cycle phase transition#GO:0044772;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell cycle G1/S phase transition#GO:0044843;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;G1/S transition of mitotic cell cycle#GO:0000082;positive regulation of cell cycle G1/S phase transition#GO:1902808;positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554 kinase activator#PC00138 Cell cycle#P00013>Cyclin D#P00484 MONDO|Ensembl=ENSMODG00000028063.2|UniProtKB=K7E2T5 K7E2T5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000048616.1|UniProtKB=A0A5F8H4W6 A0A5F8H4W6 PTHR14002:SF31 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA LIKE DOMAIN CONTAINING 2 immune system process#GO:0002376;leukocyte migration#GO:0050900;myeloid leukocyte migration#GO:0097529;cellular process#GO:0009987;granulocyte migration#GO:0097530;cell motility#GO:0048870;cell migration#GO:0016477;neutrophil migration#GO:1990266 apical part of cell#GO:0045177;extracellular region#GO:0005576;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013902.4|UniProtKB=F6VBR8 F6VBR8 GAPDHS PTHR10836:SF79 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, TESTIS-SPECIFIC glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 Huntington disease#P00029>GAPDH#P00810 MONDO|Ensembl=ENSMODG00000008587.4|UniProtKB=F7CCB2 F7CCB2 DHRS7 PTHR44269:SF1 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7-RELATED DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000016686.3|UniProtKB=F7DMD7 F7DMD7 PRR35 PTHR14678:SF2 PROLINE-RICH PROTEIN 35-RELATED PROLINE-RICH PROTEIN 35 MONDO|Ensembl=ENSMODG00000003903.4|UniProtKB=F6S3S1 F6S3S1 NOS3 PTHR19384:SF66 NITRIC OXIDE SYNTHASE-RELATED NITRIC OXIDE SYNTHASE 3 carbohydrate derivative binding#GO:0097367;monooxygenase activity#GO:0004497;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;nucleoside phosphate binding#GO:1901265;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to external biotic stimulus#GO:0043207;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;response to bacterium#GO:0009617;circulatory system process#GO:0003013;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;carboxylic acid catabolic process#GO:0046395;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;response to other organism#GO:0051707;blood circulation#GO:0008015;proteinogenic amino acid metabolic process#GO:0170039;multicellular organismal process#GO:0032501;system process#GO:0003008;response to external stimulus#GO:0009605;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;carboxylic acid metabolic process#GO:0019752;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;regulation of biological quality#GO:0065008;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to hormone#GO:0009725;arginine metabolic process#GO:0006525;intracellular signaling cassette#GO:0141124;response to chemical#GO:0042221;response to lipid#GO:0033993;metabolic process#GO:0008152;response to lipopolysaccharide#GO:0032496 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Angiogenesis#P00005>eNOS#P00210;Endothelin signaling pathway#P00019>eNOS#P00578;PI3 kinase pathway#P00048>NOS#P01205;VEGF signaling pathway#P00056>eNOS#P01422;Interleukin signaling pathway#P00036>eNOS#P00986 MONDO|Ensembl=ENSMODG00000017567.4|UniProtKB=F7BSI0 F7BSI0 COCH PTHR24020:SF36 COLLAGEN ALPHA COCHLIN sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;sensory perception of sound#GO:0007605;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000007635.4|UniProtKB=F7BKI3 F7BKI3 AKT2 PTHR24356:SF176 SERINE/THREONINE-PROTEIN KINASE RAC-BETA SERINE_THREONINE-PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 response to chemical#GO:0042221;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;response to hormone#GO:0009725;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;positive regulation of cell motility#GO:2000147;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;response to peptide hormone#GO:0043434;negative regulation of apoptotic process#GO:0043066;cellular response to nitrogen compound#GO:1901699;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of locomotion#GO:0040017;regulation of cell migration#GO:0030334;cellular response to insulin stimulus#GO:0032869;negative regulation of cellular process#GO:0048523;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AKT#P00827;PI3 kinase pathway#P00048>PKB#P01179;EGF receptor signaling pathway#P00018>Akt#P00551;Hypoxia response via HIF activation#P00030>AKT#P00819;Huntington disease#P00029>Akt#P00805;Angiogenesis#P00005>Akt#P00223;Endothelin signaling pathway#P00019>Akt#P00589;FGF signaling pathway#P00021>Akt#P00632;PDGF signaling pathway#P00047>PKB#P01151;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>AKT#P00894;Apoptosis signaling pathway#P00006>AKT#P00260;Interleukin signaling pathway#P00036>PKB#P00973;p53 pathway feedback loops 2#P04398>AKT#P04665;T cell activation#P00053>Akt#P01332;p53 pathway by glucose deprivation#P04397>Akt#P04641;FAS signaling pathway#P00020>ASK1#P00614;p53 pathway#P00059>Akt#P01486 MONDO|Ensembl=ENSMODG00000009899.3|UniProtKB=F6UUZ4 F6UUZ4 SYP PTHR10306:SF10 SYNAPTOPHYSIN SYNAPTOPHYSIN regulation of neuronal synaptic plasticity#GO:0048168;regulation of biological quality#GO:0065008;regulation of synaptic plasticity#GO:0048167;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;presynaptic active zone#GO:0048786;cytoplasm#GO:0005737;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;presynapse#GO:0098793;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>Synaptophysin#P05777 MONDO|Ensembl=ENSMODG00000001373.4|UniProtKB=F7FJK8 F7FJK8 PTHR47966:SF24 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED RENIN peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;system process#GO:0003008;metabolic process#GO:0008152;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;gene expression#GO:0010467;hormone metabolic process#GO:0042445;blood circulation#GO:0008015;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;peptide hormone processing#GO:0016486;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of biological quality#GO:0065008;circulatory system process#GO:0003013;proteolysis#GO:0006508;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;aspartic protease#PC00053 MONDO|Ensembl=ENSMODG00000019914.4|UniProtKB=F6VPI0 F6VPI0 PTHR46712:SF2 PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1 PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000051206.1|UniProtKB=A0A5F8GIL0 A0A5F8GIL0 PTHR23049:SF36 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 10 cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;mitochondrion#GO:0005739 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000003946.4|UniProtKB=A0A5F8GYR6 A0A5F8GYR6 MAPK9 PTHR24055:SF172 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 9 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;JNK cascade#GO:0007254;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 B cell activation#P00010>Jnk#P00402;Ras Pathway#P04393>JNK#P04572;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Huntington disease#P00029>JNK-2#P00799;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;FAS signaling pathway#P00020>JNK#P00615;EGF receptor signaling pathway#P00018>JNK1-3#P00545;Integrin signalling pathway#P00034>Jnk#P00951;FGF signaling pathway#P00021>JNK1-3#P00628;TGF-beta signaling pathway#P00052>JNK#P01284;T cell activation#P00053>Jnk#P01336;Parkinson disease#P00049>SAPK#P01219;Toll receptor signaling pathway#P00054>JNK#P01375;Oxidative stress response#P00046>JNK1/2#P01129;Apoptosis signaling pathway#P00006>JNK#P00274;CCKR signaling map#P06959>MAPK8-10#P07090;Gonadotropin-releasing hormone receptor pathway#P06664>JNK1/2#P06847 MONDO|Ensembl=ENSMODG00000000497.4|UniProtKB=F6TUC2 F6TUC2 CCDC93 PTHR16441:SF10 FIDIPIDINE COILED-COIL DOMAIN-CONTAINING PROTEIN 93 intracellular transport#GO:0046907;transport#GO:0006810;localization within membrane#GO:0051668;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000015323.4|UniProtKB=A0A5F8GAP3 A0A5F8GAP3 STK26 PTHR48012:SF7 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE 26 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell migration#GO:0030334;negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;regulation of locomotion#GO:0040012 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000007158.4|UniProtKB=F6RD94 F6RD94 LOC100027651 PTHR25465:SF34 B-BOX DOMAIN CONTAINING TRIPARTITE MOTIF-CONTAINING 80 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000016114.4|UniProtKB=F7EAT1 F7EAT1 EPHB2 PTHR46877:SF11 EPH RECEPTOR A5 EPHRIN TYPE-B RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;axon guidance#GO:0007411;axon development#GO:0061564;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197 PDGF signaling pathway#P00047>PDGF receptor B#P01156;Angiogenesis#P00005>EphR#P00212 MONDO|Ensembl=ENSMODG00000019913.4|UniProtKB=F6VPK7 F6VPK7 CELF1 PTHR24012:SF686 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 1 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;cellular component assembly#GO:0022607;gene expression#GO:0010467;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of mRNA metabolic process#GO:1903311;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of mRNA splicing, via spliceosome#GO:0048024;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions#GO:0000375;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;biosynthetic process#GO:0009058;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000000859.4|UniProtKB=F7BHT6 F7BHT6 PTHR23036:SF79 CYTOKINE RECEPTOR INTERLEUKIN-12 RECEPTOR SUBUNIT BETA-2 cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;coreceptor activity#GO:0015026;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974 MONDO|Ensembl=ENSMODG00000001901.4|UniProtKB=F6W1V1 F6W1V1 GRAMD2A PTHR46973:SF1 GRAM DOMAIN-CONTAINING PROTEIN 2A GRAM DOMAIN-CONTAINING PROTEIN 2A phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546 regulation of biological process#GO:0050789;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of transport#GO:0051049;regulation of localization#GO:0032879 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;organelle membrane contact site#GO:0044232;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 MONDO|Ensembl=ENSMODG00000048202.1|UniProtKB=A0A5F8GP06 A0A5F8GP06 PTHR22748:SF23 AP ENDONUCLEASE EXODEOXYRIBONUCLEASE III exonuclease activity#GO:0004527;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;DNA endonuclease activity#GO:0004520;DNA exonuclease activity#GO:0004529;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000024571.1|UniProtKB=F7BTE3 F7BTE3 OR1F1 PTHR48001:SF98 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1F1-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001842.4|UniProtKB=F6SPG8 F6SPG8 PTHR12287:SF22 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE 8-LIKE PROTEIN 3 protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of cell projection organization#GO:0031344;regulation of response to stimulus#GO:0048583;positive regulation of cellular component biogenesis#GO:0044089;small GTPase-mediated signal transduction#GO:0007264;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;intracellular signal transduction#GO:0035556;regulation of cell projection assembly#GO:0060491;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component organization#GO:0051130;positive regulation of cell projection organization#GO:0031346;regulation of signaling#GO:0023051;regulation of plasma membrane bounded cell projection assembly#GO:0120032;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of cellular component biogenesis#GO:0044087;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;ruffle#GO:0001726 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000025253.3|UniProtKB=F7F5Y0 F7F5Y0 KLHL15 PTHR45632:SF12 LD33804P KELCH-LIKE PROTEIN 15 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein metabolic process#GO:0019538;regulation of double-strand break repair#GO:2000779;cellular response to topologically incorrect protein#GO:0035967;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;regulation of macromolecule metabolic process#GO:0060255;negative regulation of DNA recombination#GO:0045910;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;cellular response to misfolded protein#GO:0071218;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular response to stress#GO:0080135;regulation of DNA recombination#GO:0000018;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of double-strand break repair via homologous recombination#GO:0010569;response to topologically incorrect protein#GO:0035966;negative regulation of metabolic process#GO:0009892;response to misfolded protein#GO:0051788;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of double-strand break repair via homologous recombination#GO:2000042;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017867.4|UniProtKB=F6YI89 F6YI89 PTHR46541:SF1 ZINC FINGER PROTEIN AEBP2 ZINC FINGER PROTEIN AEBP2 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;PcG protein complex#GO:0031519;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000010543.4|UniProtKB=F6YS11 F6YS11 CHUK PTHR22969:SF13 IKB KINASE INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT ALPHA protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;response to tumor necrosis factor#GO:0034612;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;tumor necrosis factor-mediated signaling pathway#GO:0033209;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 B cell activation#P00010>IKK#P00397;T cell activation#P00053>IKK#P01330;PDGF signaling pathway#P00047>Ikk#P01146;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IKK#P00871;Toll receptor signaling pathway#P00054>IKKalpha#P01345;Apoptosis signaling pathway#P00006>IKK#P00313;Interleukin signaling pathway#P00036>Ikk#P00968 MONDO|Ensembl=ENSMODG00000011483.4|UniProtKB=F6VJD5 F6VJD5 DNASE2 PTHR10858:SF9 DEOXYRIBONUCLEASE II DEOXYRIBONUCLEASE-2-ALPHA nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097 execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cell death#GO:0008219;nucleic acid metabolic process#GO:0090304;programmed cell death#GO:0012501;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;catabolic process#GO:0009056;DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 endodeoxyribonuclease#PC00093 MONDO|Ensembl=ENSMODG00000004844.4|UniProtKB=A0A5F8HC64 A0A5F8HC64 PTHR22792:SF48 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 4 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000041901.1|UniProtKB=F6X745 F6X745 LOC103097245 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;signaling#GO:0023052;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;cell communication#GO:0007154;regulation of immune response#GO:0050776;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000045685.1|UniProtKB=A0A5F8H887 A0A5F8H887 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024115.3|UniProtKB=F6V5R5 F6V5R5 UQCC5 PTHR35250:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 4 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 5 MONDO|Ensembl=ENSMODG00000009029.4|UniProtKB=F7B2W5 F7B2W5 E2F8 PTHR12081:SF40 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F8 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000010759.4|UniProtKB=F7FK91 F7FK91 PTHR31911:SF1 PROTEIN FAM133 FAMILY WITH SEQUENCE SIMILARITY 133 MEMBER B-RELATED RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000012717.4|UniProtKB=A0A5F8H4U5 A0A5F8H4U5 BICD1 PTHR31233:SF3 BICAUDAL D FAMILY MEMBER PROTEIN BICAUDAL D HOMOLOG 1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cytoskeletal adaptor activity#GO:0008093;cytoskeletal protein binding#GO:0008092 regulation of endocytosis#GO:0030100;microtubule anchoring at microtubule organizing center#GO:0072393;cellular component organization or biogenesis#GO:0071840;microtubule anchoring#GO:0034453;regulation of localization#GO:0032879;regulation of transport#GO:0051049;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;organelle organization#GO:0006996;macromolecule localization#GO:0033036;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;cellular process#GO:0009987;positive regulation of endocytosis#GO:0045807;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of microtubule-based process#GO:0032886;positive regulation of cellular component organization#GO:0051130;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000002610.4|UniProtKB=F7G4M4 F7G4M4 CLTA PTHR10639:SF1 CLATHRIN LIGHT CHAIN CLATHRIN LIGHT CHAIN A clathrin binding#GO:0030276;binding#GO:0005488;protein binding#GO:0005515 clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898 membrane protein complex#GO:0098796;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;intracellular membrane-bounded organelle#GO:0043231;membrane coat#GO:0030117;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;plasma membrane#GO:0005886;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;cellular anatomical structure#GO:0110165;synapse#GO:0045202;clathrin coat#GO:0030118;organelle#GO:0043226;coated vesicle membrane#GO:0030662;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;coated membrane#GO:0048475;coated vesicle#GO:0030135;secretory vesicle#GO:0099503;presynapse#GO:0098793;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle coat#GO:0030120;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle membrane#GO:0030665;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150;vesicle coat protein#PC00235 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Huntington disease#P00029>Clathrin#P00798 MONDO|Ensembl=ENSMODG00000017680.3|UniProtKB=F7GFP7 F7GFP7 PTHR11475:SF144 OXIDASE/PEROXIDASE DUAL OXIDASE catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 MONDO|Ensembl=ENSMODG00000005857.4|UniProtKB=A0A5F8GE67 A0A5F8GE67 JAKMIP2 PTHR18935:SF7 GOLGIN SUBFAMILY A MEMBER 4-LIKE ISOFORM X1 JANUS KINASE AND MICROTUBULE-INTERACTING PROTEIN 2 MONDO|Ensembl=ENSMODG00000005239.4|UniProtKB=A0A5F8G664 A0A5F8G664 UBE3C PTHR45700:SF2 UBIQUITIN-PROTEIN LIGASE E3C UBIQUITIN-PROTEIN LIGASE E3C ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 MONDO|Ensembl=ENSMODG00000006842.4|UniProtKB=A0A5F8GEG0 A0A5F8GEG0 MAP1LC3C PTHR10969:SF50 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED MICROTUBULE-ASSOCIATED PROTEIN 1 LIGHT CHAIN 3 GAMMA protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;lipid binding#GO:0008289;phospholipid binding#GO:0005543;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899 cellular component assembly#GO:0022607;macroautophagy#GO:0016236;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;organelle organization#GO:0006996;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;autophagosome maturation#GO:0097352;autophagy of mitochondrion#GO:0000422;cellular response to starvation#GO:0009267;metabolic process#GO:0008152;cellular response to nutrient levels#GO:0031669;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;cellular component disassembly#GO:0022411;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925;cellular response to stress#GO:0033554 membrane#GO:0016020;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;autophagosome#GO:0005776;intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;membrane-bounded organelle#GO:0043227 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000015286.4|UniProtKB=F7CM70 F7CM70 EIF2AK2 PTHR11042:SF163 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED INTERFERON-INDUCED, DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>PKR#P00293 MONDO|Ensembl=ENSMODG00000009735.4|UniProtKB=F6X9I4 F6X9I4 SCN4A PTHR10037:SF223 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 4 SUBUNIT ALPHA monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated sodium channel activity#GO:0005248;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium channel activity#GO:0005272;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;system process#GO:0003008;transport#GO:0006810;multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;nervous system process#GO:0050877;sensory perception#GO:0007600;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;sensory perception of pain#GO:0019233;sodium ion transport#GO:0006814;action potential#GO:0001508 transporter complex#GO:1990351;cation channel complex#GO:0034703;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000015966.4|UniProtKB=A0A5F8GCP0 A0A5F8GCP0 KIF17 PTHR24115:SF1046 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF17 isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;axo-dendritic transport#GO:0008088;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;microtubule#GO:0005874;intracellular organelle#GO:0043229;cilium#GO:0005929 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000011101.4|UniProtKB=F7DL24 F7DL24 RDM1 PTHR31164:SF1 RAD52 MOTIF-CONTAINING PROTEIN 1 RAD52 MOTIF-CONTAINING PROTEIN 1 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000006576.4|UniProtKB=F7F869 F7F869 COG1 PTHR31658:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000019581.4|UniProtKB=F7EZE4 F7EZE4 ACAN PTHR22804:SF42 AGGRECAN/VERSICAN PROTEOGLYCAN AGGRECAN CORE PROTEIN animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;system development#GO:0048731;central nervous system development#GO:0007417;multicellular organismal process#GO:0032501;nervous system development#GO:0007399 extracellular matrix#GO:0031012;membrane#GO:0016020;external encapsulating structure#GO:0030312;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;extracellular region#GO:0005576;cell junction#GO:0030054 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000018213.4|UniProtKB=F6PGH2 F6PGH2 MDN1 PTHR48103:SF2 MIDASIN-RELATED MIDASIN hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 protein-RNA complex assembly#GO:0022618;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000016792.4|UniProtKB=F7G668 F7G668 LRP11 PTHR46876:SF1 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 MONDO|Ensembl=ENSMODG00000021195.4|UniProtKB=F6XE61 F6XE61 ACSL3 PTHR43272:SF13 LONG-CHAIN-FATTY-ACID--COA LIGASE FATTY ACID COA LIGASE ACSL3 ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;long-chain fatty acid metabolic process#GO:0001676;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron differentiation#GO:0030182;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;nucleoside phosphate metabolic process#GO:0006753;cell differentiation#GO:0030154;small molecule metabolic process#GO:0044281;generation of neurons#GO:0048699;oxoacid metabolic process#GO:0043436;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856 cell periphery#GO:0071944;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;lipid droplet#GO:0005811;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ligase#PC00142 MONDO|Ensembl=ENSMODG00000008112.4|UniProtKB=F7G5I8 F7G5I8 UBAP1 PTHR15960:SF2 LD44032P UBIQUITIN-ASSOCIATED PROTEIN 1 binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;ESCRT I complex#GO:0000813;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796 MONDO|Ensembl=ENSMODG00000040409.1|UniProtKB=A0A5F8G594 A0A5F8G594 PTHR23304:SF189 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000028045.2|UniProtKB=K7E1L7 K7E1L7 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000039682.1|UniProtKB=K7E3H2 K7E3H2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000003251.4|UniProtKB=F6T1P4 F6T1P4 CPN1 PTHR11532:SF80 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE N CATALYTIC CHAIN exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235 peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190 MONDO|Ensembl=ENSMODG00000041733.1|UniProtKB=A0A5F8GLP6 A0A5F8GLP6 SDF2L1 PTHR46809:SF1 STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN 1 MONDO|Ensembl=ENSMODG00000015369.4|UniProtKB=F6WHJ0 F6WHJ0 PRKAG3 PTHR13780:SF31 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-3 ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;cation binding#GO:0043169;nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;cellular response to stress#GO:0033554;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to starvation#GO:0042594;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;cellular response to nutrient levels#GO:0031669;regulation of carbohydrate metabolic process#GO:0006109;cellular response to starvation#GO:0009267;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;cellular response to glucose starvation#GO:0042149;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;response to nutrient levels#GO:0031667;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535 kinase modulator#PC00140 MONDO|Ensembl=ENSMODG00000005335.3|UniProtKB=F7CI53 F7CI53 DPEP2 PTHR10443:SF9 MICROSOMAL DIPEPTIDASE DIPEPTIDASE 2 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000048925.1|UniProtKB=A0A5F8GZW8 A0A5F8GZW8 PTHR24379:SF131 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 712 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000016665.4|UniProtKB=A0A5F8G304 A0A5F8G304 AXIN1 PTHR46102:SF3 AXIN AXIN-1 protein binding#GO:0005515;beta-catenin binding#GO:0008013;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;identical protein binding#GO:0042802;ubiquitin protein ligase binding#GO:0031625;ubiquitin-like protein ligase binding#GO:0044389 developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;cellular developmental process#GO:0048869;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;anatomical structure development#GO:0048856;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;negative regulation of signal transduction#GO:0009968;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of Wnt signaling pathway#GO:0030111;cell development#GO:0048468;cell differentiation#GO:0030154 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>Axin#P01429;Angiogenesis#P00005>Axin#P00253;Wnt signaling pathway#P00057>Wnt Target Genes#G01558 MONDO|Ensembl=ENSMODG00000018969.4|UniProtKB=F7G034 F7G034 LRRC73 PTHR24111:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 73 MONDO|Ensembl=ENSMODG00000036870.1|UniProtKB=A0A5F8GBZ6 A0A5F8GBZ6 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000042473.1|UniProtKB=F6TRY7 F6TRY7 PTHR23087:SF12 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-14 chromatin binding#GO:0003682;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000005993.4|UniProtKB=F6SL91 F6SL91 RRM2B PTHR23409:SF19 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 B biosynthetic process#GO:0009058;metabolic process#GO:0008152;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 reductase#PC00198;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921;De novo purine biosynthesis#P02738>GDP reductase#P02909 MONDO|Ensembl=ENSMODG00000048630.1|UniProtKB=A0A5F8HKP0 A0A5F8HKP0 LOC100616772 PTHR24242:SF388 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000024763.2|UniProtKB=F7DVJ4 F7DVJ4 GPR171 PTHR24233:SF4 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 171 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000041044.1|UniProtKB=F6Y0P4 F6Y0P4 PTHR23262:SF7 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 2-2-RELATED structural protein#PC00211 MONDO|Ensembl=ENSMODG00000045170.1|UniProtKB=A0A5F8H0Q3 A0A5F8H0Q3 LOC100020170 PTHR48002:SF21 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000039308.1|UniProtKB=A0A5F8G606 A0A5F8G606 PTHR11592:SF143 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824 cellular response to oxidative stress#GO:0034599;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554 oxidoreductase#PC00176;peroxidase#PC00180 MONDO|Ensembl=ENSMODG00000018803.4|UniProtKB=F6ZME1 F6ZME1 GCM1 PTHR12414:SF6 GLIAL CELLS MISSING RELATED/GLIDE CHORION-SPECIFIC TRANSCRIPTION FACTOR GCMA transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;embryo development#GO:0009790;nervous system development#GO:0007399;cellular process#GO:0009987;animal organ development#GO:0048513;multicellular organism development#GO:0007275;placenta development#GO:0001890;gliogenesis#GO:0042063;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;developmental process#GO:0032502 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000044498.1|UniProtKB=A0A5F8G3P9 A0A5F8G3P9 PPM1E PTHR13832:SF535 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1E hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 positive regulation of cellular component biogenesis#GO:0044089;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of actin filament bundle assembly#GO:0032233;regulation of actin filament-based process#GO:0032970;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;signaling#GO:0023052;regulation of actin filament bundle assembly#GO:0032231;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;positive regulation of organelle organization#GO:0010638;cell communication#GO:0007154;positive regulation of cellular component organization#GO:0051130 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000048130.1|UniProtKB=A0A5F8G597 A0A5F8G597 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000018211.4|UniProtKB=F6PGV7 F6PGV7 EMP1 PTHR10671:SF6 EPITHELIAL MEMBRANE PROTEIN-RELATED EPITHELIAL MEMBRANE PROTEIN 1 cellular component organization or biogenesis#GO:0071840;bleb assembly#GO:0032060;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000016845.4|UniProtKB=F6QHS5 F6QHS5 NKAIN4 PTHR13084:SF5 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 4 regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of localization#GO:0032879;regulation of transport#GO:0051049;biological regulation#GO:0065007;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000006020.3|UniProtKB=F7AJ68 F7AJ68 SLC9A5 PTHR10110:SF56 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 5 monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297 regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000018540.4|UniProtKB=F7GD33 F7GD33 NCK1 PTHR19969:SF16 SH2-SH3 ADAPTOR PROTEIN-RELATED SH2_SH3 ADAPTER PROTEIN NCK1 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;signaling receptor binding#GO:0005102;binding#GO:0005488;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090 positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of cell communication#GO:0010648;regulation of cellular response to stress#GO:0080135;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;cell motility#GO:0048870;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of macromolecule metabolic process#GO:0060255;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of response to endoplasmic reticulum stress#GO:1905897;ephrin receptor signaling pathway#GO:0048013;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;positive regulation of translation#GO:0045727;response to endoplasmic reticulum stress#GO:0034976;regulation of apoptotic signaling pathway#GO:2001233;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell migration#GO:0016477;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;post-transcriptional regulation of gene expression#GO:0010608;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 T cell activation#P00053>nck#P01314;PDGF signaling pathway#P00047>Grb2#P01148;Angiogenesis#P00005>Nck#P00215;PDGF signaling pathway#P00047>Nck#P01147 MONDO|Ensembl=ENSMODG00000021104.3|UniProtKB=F6UHY3 F6UHY3 OTC PTHR45753:SF8 ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL ORNITHINE TRANSCARBAMYLASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741 small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transferase#PC00220 Arginine biosynthesis#P02728>Ornithine carbamoyl transferase#P02846 MONDO|Ensembl=ENSMODG00000035809.2|UniProtKB=A0A5F8GMM6 A0A5F8GMM6 LOC103094058 PTHR24103:SF564 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN LIGASE TRIM40 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000000272.4|UniProtKB=F6WB86 F6WB86 MYOZ1 PTHR15941:SF11 MYOZENIN MYOZENIN-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;molecular condensate scaffold activity#GO:0140693 organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;supramolecular fiber organization#GO:0097435;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;cellular response to stimulus#GO:0051716;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;developmental process#GO:0032502;cellular developmental process#GO:0048869;system process#GO:0003008;skeletal muscle tissue development#GO:0007519;multicellular organismal process#GO:0032501;tissue development#GO:0009888;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;striated muscle cell development#GO:0055002;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;response to stimulus#GO:0050896;cell differentiation#GO:0030154;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cellular anatomical entity morphogenesis#GO:0032989;muscle organ development#GO:0007517;striated muscle tissue development#GO:0014706;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;I band#GO:0031674;cytoskeleton#GO:0005856;sarcomere#GO:0030017;membraneless organelle#GO:0043228;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000012242.3|UniProtKB=K7E359 K7E359 B4GALNT2 PTHR15046:SF2 GLYCO_TRANS_2-LIKE DOMAIN-CONTAINING PROTEIN N-ACETYLNEURAMINYLGALACTOSYLGLUCOSYL-GLUCOSIDE BETA-1,4-N- ACETYLGALACTOSAMINYLTRANSFERASE 2 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 nucleoside phosphate metabolic process#GO:0006753;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;UDP-N-acetylglucosamine metabolic process#GO:0006047;metabolic process#GO:0008152 MONDO|Ensembl=ENSMODG00000009329.4|UniProtKB=F7GB00 F7GB00 PTHR23503:SF32 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 5 carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 carbohydrate transport#GO:0008643;transport#GO:0006810;localization#GO:0051179;import into cell#GO:0098657;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;import across plasma membrane#GO:0098739;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000017991.4|UniProtKB=F7B8F9 F7B8F9 M6PR PTHR15071:SF29 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER CATION-DEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR protein-containing complex binding#GO:0044877;binding#GO:0005488 protein localization to lysosome#GO:0061462;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;protein localization to organelle#GO:0033365;lysosomal transport#GO:0007041;protein localization to vacuole#GO:0072665;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234 Golgi apparatus#GO:0005794;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;late endosome#GO:0005770;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000013326.4|UniProtKB=A0A5F8G7T4 A0A5F8G7T4 PTHR19212:SF6 LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 2 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000024704.2|UniProtKB=F7AEY6 F7AEY6 TLR5 PTHR24365:SF525 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 5 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;toll-like receptor signaling pathway#GO:0002224;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;regulation of innate immune response#GO:0045088;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024181.3|UniProtKB=F7C1B7 F7C1B7 VN2R641 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000051112.1|UniProtKB=A0A5F8GS43 A0A5F8GS43 LOC103106469 PTHR48001:SF27 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000043408.1|UniProtKB=A0A5F8HEV8 A0A5F8HEV8 MPV17 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227 MONDO|Ensembl=ENSMODG00000019289.3|UniProtKB=F6RZT1 F6RZT1 SDF2 PTHR46809:SF3 STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN STROMAL CELL-DERIVED FACTOR 2 MONDO|Ensembl=ENSMODG00000044327.1|UniProtKB=F6T901 F6T901 VN2R556 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024094.3|UniProtKB=F6RKD4 F6RKD4 PTHR24103:SF676 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000012791.3|UniProtKB=A0A5F8H5R1 A0A5F8H5R1 INSM2 PTHR15065:SF6 INSULINOMA-ASSOCIATED 1 INSULINOMA-ASSOCIATED PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217 multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;neuron differentiation#GO:0030182;nervous system development#GO:0007399;regulation of cell cycle process#GO:0010564;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000051366.1|UniProtKB=K7E3X7 K7E3X7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000000357.4|UniProtKB=F6RU67 F6RU67 HEPHL1 PTHR11709:SF233 MULTI-COPPER OXIDASE FERROXIDASE HEPHL1 catalytic activity#GO:0003824;oxidoreductase activity, acting on metal ions#GO:0016722;oxidoreductase activity#GO:0016491 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 oxidase#PC00175 MONDO|Ensembl=ENSMODG00000007184.4|UniProtKB=F6XAM8 F6XAM8 NCF2 PTHR15175:SF3 NEUTROPHIL CYTOSOLIC FACTOR 2, NEUTROPHIL NADPH OXIDASE FACTOR 2 NEUTROPHIL CYTOSOL FACTOR 2 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;superoxide metabolic process#GO:0006801 catalytic complex#GO:1902494;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000000031.3|UniProtKB=F6S1D6 F6S1D6 ANAPC16 PTHR31564:SF0 ANAPHASE-PROMOTING COMPLEX SUBUNIT 16 ANAPHASE-PROMOTING COMPLEX SUBUNIT 16 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 condensed chromosome, centromeric region#GO:0000779;cytosol#GO:0005829;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;chromosome#GO:0005694;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000024724.2|UniProtKB=F7EYB3 F7EYB3 TMEM200C PTHR31815:SF2 AGAP005329-PA TRANSMEMBRANE PROTEIN 200C MONDO|Ensembl=ENSMODG00000041355.1|UniProtKB=F7E1H0 F7E1H0 LOC100031169 PTHR24249:SF271 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 6 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000021039.4|UniProtKB=A0A5F8GDS6 A0A5F8GDS6 TRAPPC10 PTHR13251:SF3 EPILEPSY HOLOPROSENCEPHALY CANDIDATE 1/TMEM1 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 10 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;TRAPPII protein complex#GO:1990071;vesicle#GO:0031982;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;TRAPP complex#GO:0030008 MONDO|Ensembl=ENSMODG00000005006.4|UniProtKB=A0A5F8HE67 A0A5F8HE67 RBM33 PTHR22014:SF2 RNA-BINDING PROTEIN 33 RNA-BINDING PROTEIN 33 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 MONDO|Ensembl=ENSMODG00000050686.1|UniProtKB=K7DYS1 K7DYS1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000003205.4|UniProtKB=F6VFV8 F6VFV8 PLA2G1B PTHR11716:SF94 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2 protein binding#GO:0005515;metal ion binding#GO:0046872;lipid binding#GO:0008289;binding#GO:0005488;calcium ion binding#GO:0005509;A2-type glycerophospholipase activity#GO:0004623;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity#GO:0016787;cation binding#GO:0043169;ion binding#GO:0043167;lipase activity#GO:0016298;signaling receptor binding#GO:0005102;small molecule binding#GO:0036094;carboxylic ester hydrolase activity#GO:0052689;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000019591.4|UniProtKB=F6Y8T8 F6Y8T8 MRPL46 PTHR13124:SF12 39S RIBOSOMAL PROTEIN L46, MITOCHONDRIAL PRECURSOR-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN ML46 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000013548.4|UniProtKB=F7C3I4 F7C3I4 PTHR23239:SF137 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 10 structural molecule activity#GO:0005198 keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;epidermis development#GO:0008544;developmental process#GO:0032502;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009;organelle organization#GO:0006996;cellular process#GO:0009987;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;skin development#GO:0043588 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000011335.2|UniProtKB=F6WHY4 F6WHY4 HARS1 PTHR11476:SF8 HISTIDYL-TRNA SYNTHETASE HISTIDINE--TRNA LIGASE, CYTOPLASMIC RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;translation#GO:0006412;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000000608.4|UniProtKB=F6TB82 F6TB82 PTHR10044:SF79 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 2 aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;enzyme regulator activity#GO:0030234;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of apoptotic process#GO:0043066;positive regulation of protein ubiquitination#GO:0031398;positive regulation of cellular process#GO:0048522;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of protein modification process#GO:0031399;regulation of protein ubiquitination#GO:0031396;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of cell cycle#GO:0051726;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 Apoptosis signaling pathway#P00006>c-IAP1,2#P00264;CCKR signaling map#P06959>BIRC2#G07278 MONDO|Ensembl=ENSMODG00000004058.4|UniProtKB=F7C2S9 F7C2S9 B4GALT1 PTHR19300:SF5 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 1 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;galactosyltransferase activity#GO:0008378;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000008063.4|UniProtKB=F6YKB6 F6YKB6 UBLCP1 PTHR48493:SF1 UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1 UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 regulation of protein-containing complex assembly#GO:0043254;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000016515.3|UniProtKB=F7EQD0 F7EQD0 PTHR14389:SF15 SI:CH1073-475A24.1 SERINE PROTEASE FAM111A-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000049133.1|UniProtKB=A0A5F8G985 A0A5F8G985 PTHR24384:SF261 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 719 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000006890.3|UniProtKB=F6PV64 F6PV64 FOXI1 PTHR11829:SF180 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN I1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000004295.4|UniProtKB=F6QG64 F6QG64 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000046694.1|UniProtKB=A0A5F8GK51 A0A5F8GK51 KNSTRN PTHR31940:SF2 SMALL KINETOCHORE-ASSOCIATED PROTEIN SMALL KINETOCHORE-ASSOCIATED PROTEIN cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of cell cycle process#GO:0010564;chromosome segregation#GO:0007059;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;regulation of cell cycle#GO:0051726;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;nuclear division#GO:0000280;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285 chromosome#GO:0005694;microtubule end#GO:1990752;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;organelle#GO:0043226;centriolar satellite#GO:0034451;mitotic spindle#GO:0072686;intracellular organelle#GO:0043229;microtubule#GO:0005874;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371 MONDO|Ensembl=ENSMODG00000020950.4|UniProtKB=A0A5F8GT21 A0A5F8GT21 SAMSN1 PTHR12301:SF4 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED SAM DOMAIN-CONTAINING PROTEIN SAMSN-1 protein binding#GO:0005515;binding#GO:0005488 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646;regulation of lymphocyte activation#GO:0051249;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;negative regulation of cell activation#GO:0050866;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of leukocyte activation#GO:0002695;regulation of multicellular organismal process#GO:0051239;negative regulation of lymphocyte activation#GO:0051250;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of B cell activation#GO:0050864 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000007190.3|UniProtKB=F6X9P7 F6X9P7 LOC130456158 PTHR19306:SF6 STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6 DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488 DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;nucleus#GO:0005634;site of double-strand break#GO:0035861;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000016318.4|UniProtKB=F7A5F7 F7A5F7 RBBP6 PTHR15439:SF0 RETINOBLASTOMA-BINDING PROTEIN 6 E3 UBIQUITIN-PROTEIN LIGASE RBBP6 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000021041.4|UniProtKB=F6VK78 F6VK78 SOD1 PTHR10003:SF112 SUPEROXIDE DISMUTASE CU-ZN -RELATED SUPEROXIDE DISMUTASE [CU-ZN] oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;copper ion binding#GO:0005507;antioxidant activity#GO:0016209;metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914 response to toxic substance#GO:0009636;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular detoxification#GO:1990748;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular oxidant detoxification#GO:0098869;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;superoxide metabolic process#GO:0006801;response to reactive oxygen species#GO:0000302;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 microbody#GO:0042579;mitochondrion#GO:0005739;nucleus#GO:0005634;cytosol#GO:0005829;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000041640.1|UniProtKB=A0A5F8H9R7 A0A5F8H9R7 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000038773.1|UniProtKB=H9H655 H9H655 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000009941.3|UniProtKB=F6R7Y9 F6R7Y9 ADPGK PTHR21208:SF0 ADP-DEPENDENT GLUCOKINASE ADP-DEPENDENT GLUCOKINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;glucose metabolic process#GO:0006006 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 kinase#PC00137 MONDO|Ensembl=ENSMODG00000048290.1|UniProtKB=F6QDB0 F6QDB0 PTHR19343:SF0 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 23_DELTA VARIABLE 6 peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000004209.4|UniProtKB=F6XR63 F6XR63 ATP8B3 PTHR24092:SF78 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IK intramembrane lipid carrier activity#GO:0140303;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;lipid transport#GO:0006869;phospholipid transport#GO:0015914;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;Golgi organization#GO:0007030 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000010334.4|UniProtKB=F6S9G8 F6S9G8 DGCR8 PTHR13482:SF3 MICRORNA PROCESSOR COMPLEX SUBUNIT DGCR8 MICROPROCESSOR COMPLEX SUBUNIT DGCR8 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725 gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;primary miRNA processing#GO:0031053;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000013724.4|UniProtKB=F6XQP6 F6XQP6 PTHR24376:SF262 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 445 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000011649.3|UniProtKB=F6TIM3 F6TIM3 PCNA PTHR11352:SF0 PROLIFERATING CELL NUCLEAR ANTIGEN DNA SLIDING CLAMP PCNA molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA-templated DNA replication#GO:0006261;DNA synthesis involved in DNA replication#GO:0090592;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298;DNA replication#GO:0006260;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA polymerase processivity factor#PC00015 DNA replication#P00017>PCNA#P00534 MONDO|Ensembl=ENSMODG00000046523.1|UniProtKB=A0A5F8GCH9 A0A5F8GCH9 PTHR28553:SF2 NEUROPEPTIDE B NEUROPEPTIDE W protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664 cell communication#GO:0007154;feeding behavior#GO:0007631;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 MONDO|Ensembl=ENSMODG00000017927.4|UniProtKB=F7EK90 F7EK90 ZMYM4 PTHR45736:SF5 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 4 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000049835.1|UniProtKB=A0A5F8GVA6 A0A5F8GVA6 monDomV1R1263 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010092.3|UniProtKB=A0A5F8H2V8 A0A5F8H2V8 CDK20 PTHR24056:SF171 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 20 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000019547.4|UniProtKB=F6UTX0 F6UTX0 SNPH PTHR16208:SF1 MICROTUBULE-ASSOCIATED PROTEIN/SYNTAPHILIN SYNTAPHILIN multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;nervous system development#GO:0007399;cellular process#GO:0009987;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;neuron differentiation#GO:0030182;generation of neurons#GO:0048699 membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytoplasmic microtubule#GO:0005881;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630 SNARE protein#PC00034 MONDO|Ensembl=ENSMODG00000014285.4|UniProtKB=A0A5F8HI79 A0A5F8HI79 DHX30 PTHR18934:SF229 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX30 nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000019894.4|UniProtKB=F6W5V4 F6W5V4 ARHGAP1 PTHR45808:SF6 RHO GTPASE-ACTIVATING PROTEIN 68F RHO GTPASE-ACTIVATING PROTEIN 1 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096 cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;negative regulation of cellular process#GO:0048523;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 PDGF signaling pathway#P00047>Rho#P01174;VEGF signaling pathway#P00056>Rac#P01421;Angiogenesis#P00005>Rac#P00245;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520 MONDO|Ensembl=ENSMODG00000017685.4|UniProtKB=F7G585 F7G585 CCDC116 PTHR36861:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 116 COILED-COIL DOMAIN-CONTAINING PROTEIN 116 MONDO|Ensembl=ENSMODG00000006867.4|UniProtKB=F6PX69 F6PX69 NAT9 PTHR13256:SF16 N-ACETYLTRANSFERASE 9 ALPHA_BETA-TUBULIN-N-ACETYLTRANSFERASE 9 protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of microtubule polymerization or depolymerization#GO:0031110;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;regulation of microtubule polymerization#GO:0031113;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;regulation of microtubule-based process#GO:0032886 MONDO|Ensembl=ENSMODG00000043792.1|UniProtKB=A0A5F8H8B9 A0A5F8H8B9 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000041446.1|UniProtKB=A0A5F8GQX4 A0A5F8GQX4 GLYATL3 PTHR15298:SF6 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000013898.3|UniProtKB=A0A5F8G8J4 A0A5F8G8J4 SLITRK2 PTHR45773:SF4 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 2 positive regulation of cellular component biogenesis#GO:0044089;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection organization#GO:0030030;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;regulation of synapse organization#GO:0050807;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;positive regulation of synapse assembly#GO:0051965;neurogenesis#GO:0022008;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;system development#GO:0048731;regulation of cell junction assembly#GO:1901888 cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cell junction#GO:0030054 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002060.4|UniProtKB=F6V029 F6V029 PTHR15153:SF0 TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 9 TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 9 tumor necrosis factor receptor superfamily binding#GO:0032813;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 positive regulation of cell adhesion#GO:0045785;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of T cell proliferation#GO:0042129;regulation of developmental process#GO:0050793;positive regulation of lymphocyte proliferation#GO:0050671;regulation of cell population proliferation#GO:0042127;positive regulation of lymphocyte activation#GO:0051251;regulation of hemopoiesis#GO:1903706;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of leukocyte proliferation#GO:0070665;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of leukocyte activation#GO:0002694;positive regulation of cell population proliferation#GO:0008284;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of lymphocyte activation#GO:0051249;positive regulation of T cell proliferation#GO:0042102;positive regulation of immune system process#GO:0002684;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of biological process#GO:0048518;regulation of T cell activation#GO:0050863;positive regulation of T cell activation#GO:0050870;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;positive regulation of leukocyte activation#GO:0002696;positive regulation of cell differentiation#GO:0045597;positive regulation of mononuclear cell proliferation#GO:0032946;regulation of leukocyte proliferation#GO:0070663 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000024004.3|UniProtKB=F7DLN2 F7DLN2 PTHR14947:SF28 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000015888.4|UniProtKB=A0A5F8HGS2 A0A5F8HGS2 CAPZB PTHR10619:SF2 F-ACTIN-CAPPING PROTEIN SUBUNIT BETA F-ACTIN-CAPPING PROTEIN SUBUNIT BETA protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of actin filament depolymerization#GO:0030834;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;actin filament-based process#GO:0030029;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of protein-containing complex assembly#GO:0031333;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835 cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000023742.3|UniProtKB=F6WRG3 F6WRG3 KCTD16 PTHR14499:SF28 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD16 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;nervous system development#GO:0007399;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856 membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;presynaptic active zone#GO:0048786;cell junction#GO:0030054;postsynapse#GO:0098794;presynaptic active zone membrane#GO:0048787;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic membrane#GO:0045211 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006844.4|UniProtKB=F6W8V3 F6W8V3 TBXA2R PTHR11866:SF5 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER THROMBOXANE A2 RECEPTOR G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of blood pressure#GO:0045777;response to stimulus#GO:0050896;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;cell communication#GO:0007154;inflammatory response#GO:0006954;circulatory system process#GO:0003013;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of blood pressure#GO:0008217;defense response#GO:0006952;system process#GO:0003008;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of anatomical structure size#GO:0090066;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of system process#GO:0044057 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014869.4|UniProtKB=F7BYB8 F7BYB8 TOM1L1 PTHR13856:SF28 VHS DOMAIN CONTAINING PROTEIN FAMILY TOM1-LIKE PROTEIN 1 clathrin binding#GO:0030276;binding#GO:0005488;protein binding#GO:0005515 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000000173.5|UniProtKB=F6X9W1 F6X9W1 DACH1 PTHR12577:SF14 DACHSHUND DACHSHUND HOMOLOG 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000039361.1|UniProtKB=A0A5F8GJT8 A0A5F8GJT8 BORCS7 PTHR31397:SF1 BLOC-1-RELATED COMPLEX SUBUNIT 7 BORSC7 BLOC-1-RELATED COMPLEX SUBUNIT 7 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000019608.3|UniProtKB=A0A5F8H682 A0A5F8H682 TRIM32 PTHR25464:SF3 TRIPARTITE MOTIF-CONTAINING PROTEIN 2-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE TRIM32 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;positive regulation of cytokine-mediated signaling pathway#GO:0001961;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;regulation of response to cytokine stimulus#GO:0060759;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular response to amino acid starvation#GO:0034198;regulation of cytokine-mediated signaling pathway#GO:0001959 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000029210.2|UniProtKB=K7E3J3 K7E3J3 PTHR19818:SF141 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;animal gross anatomical part developmental process#GO:0160108;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015792.4|UniProtKB=Q2QL96 Q2QL96 WNT2 PTHR12027:SF86 WNT RELATED PROTEIN WNT-2 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;system development#GO:0048731;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 MONDO|Ensembl=ENSMODG00000007194.4|UniProtKB=F6X9N6 F6X9N6 PTHR12644:SF1 ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 5 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;actin nucleation#GO:0045010;cell migration#GO:0016477;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 Huntington disease#P00029>Arp2/3 complex#P00811;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 MONDO|Ensembl=ENSMODG00000023108.2|UniProtKB=F7AC75 F7AC75 ACKR3 PTHR10489:SF931 CELL ADHESION MOLECULE ATYPICAL CHEMOKINE RECEPTOR 3 protein binding#GO:0005515;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896 cell chemotaxis#GO:0060326;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell communication#GO:0007154;chemotaxis#GO:0006935;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;signaling#GO:0023052;locomotion#GO:0040011;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000011271.4|UniProtKB=F6X036 F6X036 MFSD13A PTHR28658:SF3 TRANSMEMBRANE PROTEIN 180 SOLUTE CARRIER FAMILY 68 MEMBER 1 MONDO|Ensembl=ENSMODG00000024022.1|UniProtKB=F7GHG6 F7GHG6 ACKR4 PTHR10489:SF733 CELL ADHESION MOLECULE ATYPICAL CHEMOKINE RECEPTOR 4 protein binding#GO:0005515;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896 immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;signaling#GO:0023052;locomotion#GO:0040011;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;chemotaxis#GO:0006935;cell communication#GO:0007154;cell chemotaxis#GO:0060326;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000042390.1|UniProtKB=A0A5F8H6Y1 A0A5F8H6Y1 EIF4EBP3 PTHR12669:SF5 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 3 translation regulator activity#GO:0045182;protein binding#GO:0005515;translation initiation factor binding#GO:0031369;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of translation#GO:0017148;regulation of translational initiation#GO:0006446;negative regulation of macromolecule metabolic process#GO:0010605;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 translation factor#PC00223;translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000050338.1|UniProtKB=A0A5F8G644 A0A5F8G644 PTHR14224:SF9 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 14 MONDO|Ensembl=ENSMODG00000001347.4|UniProtKB=F7FWA7 F7FWA7 LYG1 PTHR31698:SF5 LYSOZYME G FAMILY MEMBER LYSOZYME G-LIKE PROTEIN 1 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;lysozyme activity#GO:0003796;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;defense response to Gram-positive bacterium#GO:0050830;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000000509.4|UniProtKB=F6Y601 F6Y601 PGR PTHR48092:SF6 KNIRPS-RELATED PROTEIN-RELATED PROGESTERONE RECEPTOR transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 cellular response to steroid hormone stimulus#GO:0071383;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;hormone-mediated signaling pathway#GO:0009755;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;response to steroid hormone#GO:0048545;intracellular receptor signaling pathway#GO:0030522;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;steroid hormone receptor signaling pathway#GO:0043401;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 Gonadotropin-releasing hormone receptor pathway#P06664>PR#P06708 MONDO|Ensembl=ENSMODG00000044337.1|UniProtKB=A0A5F8HJU4 A0A5F8HJU4 TSPAN17 PTHR19282:SF470 TETRASPANIN TETRASPANIN-17 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000016918.4|UniProtKB=F6ZUU9 F6ZUU9 PMF1 PTHR15459:SF3 POLYAMINE-MODULATED FACTOR 1 POLYAMINE-MODULATED FACTOR 1 cell cycle#GO:0007049;chromosome segregation#GO:0007059;cell cycle process#GO:0022402;cellular process#GO:0009987 membraneless organelle#GO:0043228;outer kinetochore#GO:0000940;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;kinetochore#GO:0000776 MONDO|Ensembl=ENSMODG00000048306.1|UniProtKB=A0A5F8GM90 A0A5F8GM90 PTHR23048:SF66 MYOSIN LIGHT CHAIN 1, 3 CALMODULIN 2 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000028948.2|UniProtKB=K7E0Q1 K7E0Q1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000024342.2|UniProtKB=F7B5K1 F7B5K1 PTHR16433:SF0 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3 biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;mannosyltransferase complex#GO:0031501;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090 transferase#PC00220 MONDO|Ensembl=ENSMODG00000011583.4|UniProtKB=F6XWN7 F6XWN7 PTHR18945:SF211 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-4 monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 chloride transport#GO:0006821;transport#GO:0006810;chloride transmembrane transport#GO:1902476;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220 plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944;cell junction#GO:0030054;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;synaptic membrane#GO:0097060 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000024406.2|UniProtKB=F6Z3R2 F6Z3R2 monDomV1R1259 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016166.5|UniProtKB=A0A5F8GNT8 A0A5F8GNT8 PTHR45685:SF4 HELICASE SRCAP-RELATED CHROMATIN REMODELING PROTEIN SRCAP ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;histone binding#GO:0042393;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;Swr1 complex#GO:0000812;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000024040.3|UniProtKB=F7CJB2 F7CJB2 PTHR15375:SF24 ACTIVATOR OF S-PHASE KINASE-RELATED PROTEIN DBF4 HOMOLOG B kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887 regulation of DNA replication#GO:0006275;positive regulation of metabolic process#GO:0009893;positive regulation of DNA metabolic process#GO:0051054;regulation of cell cycle phase transition#GO:1901987;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell cycle#GO:0051726;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of DNA replication#GO:0045740;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 kinase modulator#PC00140;kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000025548.3|UniProtKB=F6UJ52 F6UJ52 PTHR22910:SF6 PROTEIN MGARP PROTEIN MGARP membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000020183.4|UniProtKB=F7GHV2 F7GHV2 MPEG1 PTHR31463:SF4 MACROPHAGE-EXPRESSED GENE 1 PROTEIN MACROPHAGE-EXPRESSED GENE 1 PROTEIN defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896 MONDO|Ensembl=ENSMODG00000009162.4|UniProtKB=F7ADY5 F7ADY5 CDCA7 PTHR31169:SF2 OS05G0300700 PROTEIN CELL DIVISION CYCLE-ASSOCIATED PROTEIN 7 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000019590.4|UniProtKB=F6Y8S9 F6Y8S9 ERCC8 PTHR46202:SF1 DNA EXCISION REPAIR PROTEIN ERCC-8 DNA EXCISION REPAIR PROTEIN ERCC-8 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896 nucleus#GO:0005634;protein-containing complex#GO:0032991;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;nucleotide-excision repair complex#GO:0000109;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000045095.1|UniProtKB=A0A5F8GGZ2 A0A5F8GGZ2 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000020873.4|UniProtKB=H9H7P0 H9H7P0 PTHR45620:SF14 PDF RECEPTOR-LIKE PROTEIN-RELATED GROWTH HORMONE-RELEASING HORMONE RECEPTOR growth factor binding#GO:0019838;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002407.3|UniProtKB=A0A5F8G3R4 A0A5F8G3R4 AP1G1 PTHR22780:SF26 ADAPTIN, ALPHA/GAMMA/EPSILON AP-1 COMPLEX SUBUNIT GAMMA-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;Golgi to endosome transport#GO:0006895;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;post-Golgi vesicle-mediated transport#GO:0006892;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;vesicle coat#GO:0030120;cytoplasm#GO:0005737;clathrin-coated vesicle membrane#GO:0030665;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin vesicle coat#GO:0030125;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;coated membrane#GO:0048475;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;trans-Golgi network transport vesicle#GO:0030140;AP-1 adaptor complex#GO:0030121 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000005148.3|UniProtKB=F7EQ50 F7EQ50 NDUFS2 PTHR11993:SF48 NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity, acting on NAD(P)H#GO:0016651;NADH dehydrogenase activity#GO:0003954;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119 oxidoreductase complex#GO:1990204;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;respiratory chain complex I#GO:0045271;transporter complex#GO:1990351;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000000147.3|UniProtKB=F6XTG9 F6XTG9 TSN PTHR10741:SF2 TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X TRANSLIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000046981.1|UniProtKB=A0A5F8GZ41 A0A5F8GZ41 C2H17orf50 PTHR37878:SF1 HYPOTHETICAL PROTEIN LOC689039 SIMILAR TO HUMAN CHROMOSOME 17 OPEN READING FRAME 50 MONDO|Ensembl=ENSMODG00000007084.4|UniProtKB=F6UEK4 F6UEK4 RGS7 PTHR45746:SF7 LP21163P REGULATOR OF G PROTEIN SIGNALING 7 enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 MONDO|Ensembl=ENSMODG00000012645.4|UniProtKB=F6WE56 F6WE56 STX17 PTHR19957:SF139 SYNTAXIN SYNTAXIN-17 SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle organization#GO:0006996;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;autophagosome#GO:0005776;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421 SNARE protein#PC00034 MONDO|Ensembl=ENSMODG00000007781.2|UniProtKB=F7AWR0 F7AWR0 GABRA6 PTHR18945:SF335 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-6 transmembrane signaling receptor activity#GO:0004888;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;molecular transducer activity#GO:0060089;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;neurotransmitter receptor activity#GO:0030594;ligand-gated channel activity#GO:0022834;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion channel activity#GO:0005216;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023 establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;system development#GO:0048731;localization#GO:0051179;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;anatomical structure development#GO:0048856;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;chloride transport#GO:0006821;nervous system development#GO:0007399;cellular component assembly#GO:0022607;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;synapse assembly#GO:0007416;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;cellular component organization#GO:0016043 cell junction#GO:0030054;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell projection membrane#GO:0031253;dendritic tree#GO:0097447;leading edge membrane#GO:0031256;dendrite#GO:0030425;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000012802.3|UniProtKB=F7DZ64 F7DZ64 STARD3 PTHR46121:SF2 STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE STAR-RELATED LIPID TRANSFER PROTEIN 3 small molecule binding#GO:0036094;binding#GO:0005488;sterol binding#GO:0032934;alcohol binding#GO:0043178;lipid binding#GO:0008289;cholesterol binding#GO:0015485;steroid binding#GO:0005496 macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;lipid transport#GO:0006869;lipid localization#GO:0010876;transport#GO:0006810;localization#GO:0051179;sterol transport#GO:0015918;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850 membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;late endosome membrane#GO:0031902;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle membrane contact site#GO:0044232;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 MONDO|Ensembl=ENSMODG00000039806.1|UniProtKB=A0A5F8HAX2 A0A5F8HAX2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000002476.4|UniProtKB=F7BW40 F7BW40 NMUR1 PTHR24243:SF109 G-PROTEIN COUPLED RECEPTOR NEUROMEDIN-U RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000024389.1|UniProtKB=F6Z4Q3 F6Z4Q3 PTHR48002:SF194 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011151.4|UniProtKB=F7AN28 F7AN28 PTHR11481:SF64 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;immune response#GO:0006955;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;immune system process#GO:0002376;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000017338.3|UniProtKB=F6WVK9 F6WVK9 PHPT1 PTHR12258:SF10 JANUS-A/JANUS-B 14 KDA PHOSPHOHISTIDINE PHOSPHATASE catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000006812.4|UniProtKB=F6PGK1 F6PGK1 MCAT PTHR42681:SF8 MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000001578.4|UniProtKB=A0A5F8HE98 A0A5F8HE98 CD53 PTHR19282:SF39 TETRASPANIN LEUKOCYTE SURFACE ANTIGEN CD53 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000025559.3|UniProtKB=A0A5F8HF33 A0A5F8HF33 PTHR22950:SF708 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;amino acid transporter#PC00046 MONDO|Ensembl=ENSMODG00000012499.4|UniProtKB=F6Q2B0 F6Q2B0 MED27 PTHR13130:SF4 34 KDA TRANSCRIPTIONAL CO-ACTIVATOR-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 27 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000004283.2|UniProtKB=F6TDX6 F6TDX6 RPL8 PTHR13691:SF16 RIBOSOMAL PROTEIN L2 LARGE RIBOSOMAL SUBUNIT PROTEIN UL2 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000017054.4|UniProtKB=A0A5F8H5I7 A0A5F8H5I7 LAPTM5 PTHR12479:SF2 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 5 molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of membrane permeability#GO:0090559 lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosomal membrane#GO:0005765;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323 transporter#PC00227 MONDO|Ensembl=ENSMODG00000000895.4|UniProtKB=F7D3G3 F7D3G3 STAP2 PTHR16186:SF11 SIGNAL-TRANSDUCING ADAPTOR PROTEIN-RELATED SIGNAL-TRANSDUCING ADAPTOR PROTEIN 2 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000049658.1|UniProtKB=F6UNW6 F6UNW6 LOC100014039 PTHR28644:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 15 SMALL INTEGRAL MEMBRANE PROTEIN 15 MONDO|Ensembl=ENSMODG00000015974.4|UniProtKB=F7FCV6 F7FCV6 HP1BP3 PTHR15832:SF1 SHC (SRC HOMOLOGY DOMAIN C-TERMINAL) ADAPTOR HOMOLOG HETEROCHROMATIN PROTEIN 1-BINDING PROTEIN 3 nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000015698.4|UniProtKB=H9H7J2 H9H7J2 PTHR24147:SF53 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN 26 MONDO|Ensembl=ENSMODG00000011447.3|UniProtKB=F6W1B4 F6W1B4 HSPA12B PTHR14187:SF39 ALPHA KINASE/ELONGATION FACTOR 2 KINASE HEAT SHOCK 70 KDA PROTEIN 12B MONDO|Ensembl=ENSMODG00000007299.4|UniProtKB=F6W911 F6W911 COLGALT2 PTHR10730:SF8 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN GALACTOSYLTRANSFERASE 2 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000014074.5|UniProtKB=F7D1C4 F7D1C4 SREBF1 PTHR46062:SF2 STEROL REGULATORY ELEMENT-BINDING PROTEIN STEROL REGULATORY ELEMENT-BINDING PROTEIN 1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000006965.3|UniProtKB=F6QVB3 F6QVB3 RNASE4 PTHR11437:SF53 RIBONUCLEASE RIBONUCLEASE 4 catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;defense response#GO:0006952 endoribonuclease#PC00094;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000012058.3|UniProtKB=F7FM86 F7FM86 PTHR16024:SF15 XK-RELATED PROTEIN XK-RELATED PROTEIN 5 cellular process#GO:0009987;endomembrane system organization#GO:0010256;membrane invagination#GO:0010324;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;apoptotic cell clearance#GO:0043277;phagocytosis, engulfment#GO:0006911;cellular component organization#GO:0016043;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;endocytosis#GO:0006897;lipid localization#GO:0010876;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;macromolecule localization#GO:0033036;lipid transport#GO:0006869;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;phagocytosis#GO:0006909;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;programmed cell death#GO:0012501;cell death#GO:0008219;organophosphate ester transport#GO:0015748;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;anatomical structure development#GO:0048856;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000011329.3|UniProtKB=F6WIG3 F6WIG3 LOC103105760 PTHR26450:SF84 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51Q1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000022724.2|UniProtKB=H9H8L3 H9H8L3 MFSD5 PTHR23516:SF1 SAM (S-ADENOSYL METHIONINE) TRANSPORTER SOLUTE CARRIER FAMILY 61 MEMBER 1 transporter#PC00227 MONDO|Ensembl=ENSMODG00000000921.4|UniProtKB=F6ZGL9 F6ZGL9 SLC6A18 PTHR11616:SF109 SODIUM/CHLORIDE DEPENDENT TRANSPORTER INACTIVE SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT3 amino acid transport#GO:0006865;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 MONDO|Ensembl=ENSMODG00000025620.3|UniProtKB=A0A5F8GHU9 A0A5F8GHU9 ENOSF1 PTHR13794:SF58 ENOLASE SUPERFAMILY, MANDELATE RACEMASE MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1 epimerase/racemase#PC00096 MONDO|Ensembl=ENSMODG00000013983.4|UniProtKB=F6QL26 F6QL26 PTHR14156:SF0 MOTILIN PROMOTILIN G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 MONDO|Ensembl=ENSMODG00000017742.4|UniProtKB=F7EKV2 F7EKV2 CMAS PTHR21485:SF3 HAD SUPERFAMILY MEMBERS CMAS AND KDSC N-ACYLNEURAMINATE CYTIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 nucleotidyltransferase#PC00174;transferase#PC00220 MONDO|Ensembl=ENSMODG00000016314.3|UniProtKB=F7A5L7 F7A5L7 CEBPB PTHR23334:SF21 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN BETA binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 MONDO|Ensembl=ENSMODG00000002218.4|UniProtKB=F7DG20 F7DG20 TBC1D23 PTHR13297:SF10 TBC1 DOMAIN FAMILY MEMBER 23-RELATED TBC1 DOMAIN FAMILY MEMBER 23 cytosolic transport#GO:0016482;animal gross anatomical part developmental process#GO:0160108;embryonic organ development#GO:0048568;cellular localization#GO:0051641;anatomical structure development#GO:0048856;localization#GO:0051179;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;embryo development#GO:0009790;intracellular transport#GO:0046907;transport#GO:0006810;developmental process#GO:0032502;animal organ development#GO:0048513;establishment of localization#GO:0051234;multicellular organism development#GO:0007275;endosomal transport#GO:0016197 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791 MONDO|Ensembl=ENSMODG00000015621.4|UniProtKB=F6YFP8 F6YFP8 RGMB PTHR31428:SF5 RGM DOMAIN FAMILY MEMBER DRAG-1 REPULSIVE GUIDANCE MOLECULE B coreceptor activity#GO:0015026;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signaling#GO:0023052;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000019752.3|UniProtKB=A0A5F8HLK0 A0A5F8HLK0 WDR38 PTHR19848:SF8 WD40 REPEAT PROTEIN F-BOX_WD REPEAT-CONTAINING PROTEIN 7 Notch signaling pathway#P00045>Sel 10#P01102 MONDO|Ensembl=ENSMODG00000016981.4|UniProtKB=F6UL87 F6UL87 KHDC4 PTHR15744:SF0 BLOM7 KH HOMOLOGY DOMAIN-CONTAINING PROTEIN 4 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000051123.1|UniProtKB=F7B114 F7B114 LOC100019772 PTHR26450:SF156 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52R1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000036774.1|UniProtKB=A0A5F8HCE9 A0A5F8HCE9 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000040122.1|UniProtKB=A0A5F8GGU1 A0A5F8GGU1 CDKN2B PTHR24201:SF8 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CYCLIN-DEPENDENT KINASE 4 INHIBITOR B enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme inhibitor activity#GO:0004857;kinase inhibitor activity#GO:0019210;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;kinase regulator activity#GO:0019207 regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cellular process#GO:0048523;regulation of cell population proliferation#GO:0042127;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789;negative regulation of cell population proliferation#GO:0008285;negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987;regulation of cell cycle process#GO:0010564;regulation of cell cycle G1/S phase transition#GO:1902806;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 p53 pathway#P00059>ARF#G01574 MONDO|Ensembl=ENSMODG00000023773.2|UniProtKB=F6SDH5 F6SDH5 CD14 PTHR10630:SF3 MONOCYTE DIFFERENTIATION ANTIGEN CD14 MONOCYTE DIFFERENTIATION ANTIGEN CD14 lipid binding#GO:0008289;lipopolysaccharide binding#GO:0001530;carbohydrate derivative binding#GO:0097367;binding#GO:0005488 positive regulation of gene expression#GO:0010628;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;cellular response to molecule of bacterial origin#GO:0071219;regulation of response to stress#GO:0080134;toll-like receptor 4 signaling pathway#GO:0034142;response to other organism#GO:0051707;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;response to bacterium#GO:0009617;response to external biotic stimulus#GO:0043207;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of response to biotic stimulus#GO:0002831;positive regulation of cytokine production#GO:0001819;positive regulation of response to external stimulus#GO:0032103;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipopolysaccharide#GO:0071222;positive regulation of metabolic process#GO:0009893;response to oxygen-containing compound#GO:1901700;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;cellular response to biotic stimulus#GO:0071216;response to lipopolysaccharide#GO:0032496;immune response-activating signaling pathway#GO:0002757;positive regulation of macromolecule metabolic process#GO:0010604;cellular response to lipid#GO:0071396;regulation of response to external stimulus#GO:0032101;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to stimulus#GO:0050896;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;immune response-regulating signaling pathway#GO:0002764 cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;membrane raft#GO:0045121;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane microdomain#GO:0098857;signaling receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>CD14#P01373 MONDO|Ensembl=ENSMODG00000009585.4|UniProtKB=F6PG44 F6PG44 PTHR14659:SF1 ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34 ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000002970.4|UniProtKB=F6Q5B1 F6Q5B1 ANKH PTHR28384:SF1 PROGRESSIVE ANKYLOSIS PROTEIN HOMOLOG MINERALIZATION REGULATOR ANKH transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;phosphate transmembrane transporter activity#GO:0005315;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000024783.2|UniProtKB=F7GAU3 F7GAU3 PTHR43153:SF1 ELECTRON TRANSFER FLAVOPROTEIN ALPHA ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166 small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000002709.3|UniProtKB=F7CXV2 F7CXV2 PDE6G PTHR12122:SF4 RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE GAMMA-SUBUNIT-RELATED ROD CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT GAMMA regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583 9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;cell projection membrane#GO:0031253;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730 phosphodiesterase#PC00185 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PDEgamma#P00754 MONDO|Ensembl=ENSMODG00000037039.1|UniProtKB=A0A5F8H4D1 A0A5F8H4D1 TMEM151B PTHR31893:SF4 TRANSMEMBRANE PROTEIN 151 HOMOLOG TRANSMEMBRANE PROTEIN 151B cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000045105.1|UniProtKB=A0A5F8H057 A0A5F8H057 PTHR44826:SF5 SPORE COAT PROTEIN SP85 DYNEIN HEAVY CHAIN MONDO|Ensembl=ENSMODG00000004491.4|UniProtKB=F7BGG4 F7BGG4 TANC1 PTHR24166:SF23 ROLLING PEBBLES, ISOFORM B PROTEIN TANC1 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803;regulation of synapse organization#GO:0050807 postsynapse#GO:0098794;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006514.4|UniProtKB=H9H673 H9H673 SLC15A3 PTHR11654:SF95 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 3 oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;transmembrane transport#GO:0055085;dipeptide transport#GO:0042938;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;oligopeptide transport#GO:0006857;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;oligopeptide transmembrane transport#GO:0035672;import across plasma membrane#GO:0098739 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 MONDO|Ensembl=ENSMODG00000036884.1|UniProtKB=A0A5F8GFV0 A0A5F8GFV0 PTHR13947:SF48 GNAT FAMILY N-ACETYLTRANSFERASE N-ACETYLTRANSFERASE 8-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000012564.5|UniProtKB=F6PLD1 F6PLD1 GPR179 PTHR32546:SF7 G-PROTEIN COUPLED RECEPTOR 158-RELATED G PROTEIN-COUPLED RECEPTOR 179-RELATED transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000042388.1|UniProtKB=A0A5F8H6S4 A0A5F8H6S4 PTHR34930:SF5 GEO05313P1 JUPITER MICROTUBULE ASSOCIATED HOMOLOG 2 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000046323.1|UniProtKB=A0A5F8H4F5 A0A5F8H4F5 PTHR13087:SF0 NF-KAPPA B ACTIVATING PROTEIN NFKB ACTIVATING PROTEIN LIKE biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000017550.4|UniProtKB=F7E0Z1 F7E0Z1 STX7 PTHR19957:SF90 SYNTAXIN SYNTAXIN-7 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641 membrane#GO:0016020;secretory vesicle#GO:0099503;presynapse#GO:0098793;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;cell junction#GO:0030054;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synapse#GO:0045202;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 SNARE protein#PC00034 Parkinson disease#P00049>Syntaxin#P01215;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072 MONDO|Ensembl=ENSMODG00000000646.4|UniProtKB=A0A5F8G6J6 A0A5F8G6J6 LGR6 PTHR24372:SF73 GLYCOPROTEIN HORMONE RECEPTOR LEUCINE RICH REPEAT CONTAINING G PROTEIN-COUPLED RECEPTOR 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000007454.4|UniProtKB=F7DB20 F7DB20 TRMT1L PTHR10631:SF1 N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRNA (GUANINE(27)-N(2))-DIMETHYLTRANSFERASE tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a tRNA#GO:0140101;tRNA (guanine) methyltransferase activity#GO:0016423;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170 tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000013098.4|UniProtKB=F7EXB5 F7EXB5 UNC5CL PTHR12582:SF51 NETRIN RECEPTOR UNC5 UNC5C-LIKE PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;positive regulation of MAPK cascade#GO:0043410;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of JNK cascade#GO:0046328;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020480.3|UniProtKB=F7FIW5 F7FIW5 ACSS3 PTHR43347:SF5 ACYL-COA SYNTHETASE ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ligase#PC00142;metabolite interconversion enzyme#PC00262 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 MONDO|Ensembl=ENSMODG00000015385.4|UniProtKB=F6TL51 F6TL51 CDC37L1 PTHR12800:SF2 CDC37-RELATED HSP90 CO-CHAPERONE CDC37-LIKE 1 protein binding#GO:0005515;binding#GO:0005488;heat shock protein binding#GO:0031072 regulation of protein stability#GO:0031647;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biological regulation#GO:0065007;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protein folding chaperone complex#GO:0101031;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000011638.4|UniProtKB=A0A5F8GGV1 A0A5F8GGV1 KCNIP2 PTHR23055:SF65 CALCIUM BINDING PROTEINS A-TYPE POTASSIUM CHANNEL MODULATORY PROTEIN KCNIP2 metal ion binding#GO:0046872;cation binding#GO:0043169;channel regulator activity#GO:0016247;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;potassium channel regulator activity#GO:0015459;calcium ion binding#GO:0005509;transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106 regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;biological regulation#GO:0065007;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of cellular process#GO:0050794 monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000015973.4|UniProtKB=A0A5F8GP31 A0A5F8GP31 AGXT PTHR21152:SF40 AMINOTRANSFERASE CLASS V ALANINE--GLYOXYLATE AMINOTRANSFERASE transaminase activity#GO:0008483;catalytic activity#GO:0003824;transferase activity#GO:0016740 carboxylic acid catabolic process#GO:0046395;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;aldehyde catabolic process#GO:0046185;proteinogenic amino acid metabolic process#GO:0170039;monocarboxylic acid catabolic process#GO:0072329;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;glyoxylate metabolic process#GO:0046487;oxoacid metabolic process#GO:0043436 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transaminase#PC00216;transferase#PC00220 MONDO|Ensembl=ENSMODG00000016561.2|UniProtKB=F7DN75 F7DN75 LIPN PTHR11005:SF16 LYSOSOMAL ACID LIPASE-RELATED LIPASE MEMBER N hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 hydrolase#PC00121;lipase#PC00143 MONDO|Ensembl=ENSMODG00000043155.1|UniProtKB=A0A5F8HJM2 A0A5F8HJM2 monDomV1R1279 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012739.4|UniProtKB=F6T0E2 F6T0E2 PTHR45737:SF6 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A MONDO|Ensembl=ENSMODG00000050740.1|UniProtKB=A0A5F8HKI5 A0A5F8HKI5 RBM15 PTHR23189:SF43 RNA RECOGNITION MOTIF-CONTAINING RNA-BINDING PROTEIN 15 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000051050.1|UniProtKB=A0A5F8GSK1 A0A5F8GSK1 ZNF275 PTHR24381:SF435 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 275 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000011952.2|UniProtKB=H9H6I9 H9H6I9 PTHR36465:SF1 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 3 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 3 protein-containing complex organization#GO:0043933;energy derivation by oxidation of organic compounds#GO:0015980;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043 membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000012530.4|UniProtKB=F6PZI4 F6PZI4 TBC1D2 PTHR22957:SF570 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 2A enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000002711.4|UniProtKB=F7CXT9 F7CXT9 NRDE2 PTHR13471:SF0 TETRATRICOPEPTIDE-LIKE HELICAL NUCLEAR EXOSOME REGULATOR NRDE2 regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA metabolic process#GO:0051253;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;regulatory ncRNA-mediated heterochromatin formation#GO:0031048;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338 MONDO|Ensembl=ENSMODG00000004561.3|UniProtKB=F6R569 F6R569 MKNK2 PTHR24349:SF254 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-INTERACTING SERINE_THREONINE-PROTEIN KINASE 2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;calcium/calmodulin-dependent protein kinase activity#GO:0004683;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Interleukin signaling pathway#P00036>MNK1/2#P00972;PDGF signaling pathway#P00047>MNK1/2#P01149;p38 MAPK pathway#P05918>MNK2#P06017;Oxidative stress response#P00046>MNK1/2#P01137 MONDO|Ensembl=ENSMODG00000003120.4|UniProtKB=F6WVD2 F6WVD2 PTPN11 PTHR46559:SF1 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 cell adhesion molecule binding#GO:0050839;phosphoric ester hydrolase activity#GO:0042578;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;protein tyrosine phosphatase activity#GO:0004725;protein binding#GO:0005515;phosphatase activity#GO:0016791;receptor tyrosine kinase binding#GO:0030971;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>SHP2#P00647;CCKR signaling map#P06959>SHP-2#P07028;Interferon-gamma signaling pathway#P00035>PTP#P00960;Angiogenesis#P00005>SHP2#P00181 MONDO|Ensembl=ENSMODG00000008337.3|UniProtKB=F7F2N3 F7F2N3 QPCT PTHR12283:SF5 GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE ion binding#GO:0043167;acyltransferase activity#GO:0016746;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;zinc ion binding#GO:0008270;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 transferase#PC00220 MONDO|Ensembl=ENSMODG00000012217.3|UniProtKB=F7CE09 F7CE09 PHOSPHO1 PTHR20889:SF2 PHOSPHATASE, ORPHAN 1, 2 PHOSPHOETHANOLAMINE_PHOSPHOCHOLINE PHOSPHATASE catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 biomineral tissue development#GO:0031214;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;anatomical structure maturation#GO:0071695;animal organ morphogenesis#GO:0009887;ossification#GO:0001503;developmental process#GO:0032502;bone mineralization#GO:0030282;multicellular organism development#GO:0007275;animal organ development#GO:0048513;bone development#GO:0060348;skeletal system morphogenesis#GO:0048705;developmental maturation#GO:0021700;multicellular organismal process#GO:0032501;tissue development#GO:0009888 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000014907.3|UniProtKB=A0A5F8GWX6 A0A5F8GWX6 PPT2 PTHR11247:SF27 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 LYSOSOMAL THIOESTERASE PPT2 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;lysosome#GO:0005764;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000011985.2|UniProtKB=F7B9H2 F7B9H2 BLK PTHR24418:SF181 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE BLK protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;binding#GO:0005488;signaling receptor binding#GO:0005102;non-membrane spanning protein tyrosine kinase activity#GO:0004715;catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cellular developmental process#GO:0048869;enzyme-linked receptor protein signaling pathway#GO:0007167 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230;B cell activation#P00010>Blk#P00390 MONDO|Ensembl=ENSMODG00000014942.4|UniProtKB=K7E0T3 K7E0T3 SLC35E1 PTHR11132:SF427 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E1 active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000028569.2|UniProtKB=K7E1K9 K7E1K9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012004.3|UniProtKB=F7AMJ6 F7AMJ6 DCAF15 PTHR28541:SF1 DDB1- AND CUL4-ASSOCIATED FACTOR 15 DDB1- AND CUL4-ASSOCIATED FACTOR 15 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 MONDO|Ensembl=ENSMODG00000008226.4|UniProtKB=F7A3I9 F7A3I9 ART5 PTHR10339:SF2 ADP-RIBOSYLTRANSFERASE ECTO-ADP-RIBOSYLTRANSFERASE 5 NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 transferase#PC00220 MONDO|Ensembl=ENSMODG00000014138.4|UniProtKB=F7GKR7 F7GKR7 CFAP263 PTHR15654:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 113-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 263 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064 MONDO|Ensembl=ENSMODG00000045431.1|UniProtKB=A0A5F8HCL1 A0A5F8HCL1 FBLN5 PTHR24050:SF30 PA14 DOMAIN-CONTAINING PROTEIN FIBULIN-5 MONDO|Ensembl=ENSMODG00000015333.4|UniProtKB=A0A5F8GXN1 A0A5F8GXN1 GALNT9 PTHR11675:SF28 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 9 catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000010997.4|UniProtKB=F7A1J3 F7A1J3 CDADC1 PTHR11086:SF14 DEOXYCYTIDYLATE DEAMINASE-RELATED DCTP DEAMINASE deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 deaminase#PC00088;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000010265.3|UniProtKB=F6VPF9 F6VPF9 GALNT16 PTHR11675:SF3 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 16 UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;biosynthetic process#GO:0009058 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000028246.2|UniProtKB=A0A5F8GU85 A0A5F8GU85 SSR1 PTHR12924:SF0 TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT ALPHA intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000008738.4|UniProtKB=F6PTD8 F6PTD8 PTHR10541:SF2 PARATHYROID HORMONE PARATHYROID HORMONE signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179 intracellular calcium ion homeostasis#GO:0006874;chemical homeostasis#GO:0048878;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of multicellular organismal process#GO:0051239;renal system process#GO:0003014;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;monoatomic ion homeostasis#GO:0050801;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;system process#GO:0003008;renal absorption#GO:0070293;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;positive regulation of developmental process#GO:0051094;regulation of bone mineralization#GO:0030500;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell communication#GO:0007154;regulation of developmental process#GO:0050793;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;peptide hormone#PC00179 MONDO|Ensembl=ENSMODG00000004513.4|UniProtKB=F6V938 F6V938 PTHR35537:SF1 DNA DAMAGE-INDUCIBLE APOPTOSIS SUPPRESSOR PROTEIN DDIAS DNA DAMAGE-INDUCED APOPTOSIS SUPPRESSOR PROTEIN cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000005400.4|UniProtKB=F7G6B6 F7G6B6 PTPRA PTHR19134:SF433 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ALPHA protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 protein phosphatase#PC00195;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000003939.4|UniProtKB=F7G9T3 F7G9T3 SVEP1 PTHR19325:SF43 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 circulatory system development#GO:0072359;tissue development#GO:0009888;multicellular organismal process#GO:0032501;anatomical structure morphogenesis#GO:0009653;system development#GO:0048731;vasculature development#GO:0001944;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;developmental process#GO:0032502;epidermis development#GO:0008544;animal gross anatomical part developmental process#GO:0160108 defense/immunity protein#PC00090;complement component#PC00078 MONDO|Ensembl=ENSMODG00000007333.3|UniProtKB=F7EEW8 F7EEW8 PTHR10877:SF185 POLYCYSTIN FAMILY MEMBER POLYCYSTIN FAMILY RECEPTOR FOR EGG JELLY monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to mechanical stimulus#GO:0009612;detection of stimulus#GO:0051606;detection of mechanical stimulus#GO:0050982;response to abiotic stimulus#GO:0009628 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000051458.1|UniProtKB=A0A5F8GDX4 A0A5F8GDX4 PTHR48416:SF1 CYTOCHROME C OXIDASE SUBUNIT 6C CYTOCHROME C OXIDASE SUBUNIT 6C membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000007986.4|UniProtKB=F6QAU1 F6QAU1 PTHR28469:SF1 ECTODYSPLASIN-A RECEPTOR-ASSOCIATED ADAPTER PROTEIN ECTODYSPLASIN-A RECEPTOR-ASSOCIATED ADAPTER PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000043875.1|UniProtKB=F7C2H9 F7C2H9 LOC100013115 PTHR26453:SF58 OLFACTORY RECEPTOR OLFACTORY RECEPTOR FAMILY 13 SUBFAMILY P MEMBER 9 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000045053.1|UniProtKB=A0A5F8G8C2 A0A5F8G8C2 PTHR11849:SF209 ETS ETS TRANSLOCATION VARIANT 2 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 MONDO|Ensembl=ENSMODG00000006895.2|UniProtKB=F6PV39 F6PV39 LOC100019911 PTHR24071:SF0 RAN GTPASE GTP-BINDING NUCLEAR PROTEIN RAN ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;macromolecule biosynthetic process#GO:0009059;establishment of protein localization to organelle#GO:0072594;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;localization#GO:0051179;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;organelle localization#GO:0051640;ribosome localization#GO:0033750;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;gene expression#GO:0010467;protein export from nucleus#GO:0006611;cellular component biogenesis#GO:0044085;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit export from nucleus#GO:0000055;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;protein import into nucleus#GO:0006606;protein transport#GO:0015031;ribosome biogenesis#GO:0042254 organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;intracellular organelle#GO:0043229 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000000740.4|UniProtKB=A0A5F8HLT4 A0A5F8HLT4 PTHR23122:SF45 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PROTEIN PALS2 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000045864.1|UniProtKB=A0A5F8G5J4 A0A5F8G5J4 VN2R566 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003439.4|UniProtKB=F7DWY6 F7DWY6 SMU1 PTHR22848:SF0 WD40 REPEAT PROTEIN WD40 REPEAT-CONTAINING PROTEIN SMU1 RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000007031.3|UniProtKB=F6UFT0 F6UFT0 TPBGL PTHR24364:SF16 LP06937P TROPHOBLAST GLYCOPROTEIN-LIKE regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000050626.1|UniProtKB=A0A5F8GWZ4 A0A5F8GWZ4 VN2R554 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000017311.4|UniProtKB=F6XCP2 F6XCP2 ZMYND12 PTHR46533:SF1 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 12 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 12 MONDO|Ensembl=ENSMODG00000001954.4|UniProtKB=F6VJC7 F6VJC7 PTHR15152:SF0 CD70 ANTIGEN CD70 ANTIGEN receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;T cell activation#GO:0042110;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;cell communication#GO:0007154;cell activation#GO:0001775;immune system process#GO:0002376;biological regulation#GO:0065007;adaptive immune response#GO:0002250;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000001180.5|UniProtKB=F7GHD5 F7GHD5 BOD1L1 PTHR47391:SF1 BIORIENTATION OF CHROMOSOMES IN CELL DIVISION 1 LIKE 1 BIORIENTATION OF CHROMOSOMES IN CELL DIVISION 1 LIKE 1 MONDO|Ensembl=ENSMODG00000007070.3|UniProtKB=F6UEY0 F6UEY0 DCUN1D3 PTHR12281:SF31 RP42 RELATED DCN1-LIKE PROTEIN 3 protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;binding#GO:0005488;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;regulation of protein modification process#GO:0031399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of protein metabolic process#GO:0051246;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of macromolecule metabolic process#GO:0010604;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000003309.4|UniProtKB=F7DZ20 F7DZ20 EPHA2 PTHR24416:SF306 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-A RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023 blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;circulatory system development#GO:0072359;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;system development#GO:0048731;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008583.4|UniProtKB=F7CCU8 F7CCU8 APBB1IP PTHR11243:SF14 GROWTH FACTOR RECEPTOR-BOUND PROTEIN AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1-INTERACTING PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;cell morphogenesis#GO:0000902;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell projection organization#GO:0030030 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017709.4|UniProtKB=F7FHW5 F7FHW5 CTDSPL2 PTHR12210:SF173 DULLARD PROTEIN PHOSPHATASE CTD SMALL PHOSPHATASE-LIKE PROTEIN 2 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000013449.1|UniProtKB=F7G9J2 F7G9J2 KRT26 PTHR23239:SF162 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 26 structural molecule activity#GO:0005198 cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;morphogenesis of an epithelium#GO:0002009;developmental process#GO:0032502;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512 intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000016202.4|UniProtKB=F7FY36 F7FY36 RIMS4 PTHR12157:SF28 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 4 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;regulation of secretion#GO:0051046;regulation of exocytosis#GO:0017157;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;cellular component assembly#GO:0022607;neurotransmitter transport#GO:0006836;regulated exocytosis#GO:0045055;exocytic process#GO:0140029;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;exocytosis#GO:0006887;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of neurotransmitter secretion#GO:0046928;regulation of synaptic vesicle exocytosis#GO:2000300;signaling#GO:0023052;export from cell#GO:0140352;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;cellular localization#GO:0051641;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940 presynapse#GO:0098793;cell cortex#GO:0005938;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165;synaptic membrane#GO:0097060;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;presynaptic active zone#GO:0048786 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000015776.3|UniProtKB=F6Z4I5 F6Z4I5 CIMIP2C PTHR34924:SF1 UPF0573 PROTEIN C2ORF70 CILIARY MICROTUBULE INNER PROTEIN 2C MONDO|Ensembl=ENSMODG00000002337.4|UniProtKB=F7GLY9 F7GLY9 PTHR43948:SF6 DNAJ HOMOLOG SUBFAMILY B DNAJ HOMOLOG SUBFAMILY B MEMBER 6 protein binding#GO:0005515;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000017473.4|UniProtKB=K7DZY1 K7DZY1 LOC100022865 PTHR24028:SF254 CADHERIN-87A PROTOCADHERIN-11 X-LINKED-RELATED cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000018375.6|UniProtKB=F6QVV0 F6QVV0 PTHR10663:SF318 GUANYL-NUCLEOTIDE EXCHANGE FACTOR IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 3 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of biological quality#GO:0065008;regulation of endocytosis#GO:0030100;biological regulation#GO:0065007;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627 postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;cell junction#GO:0030054 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000003859.5|UniProtKB=F7DU06 F7DU06 SFRP5 PTHR11309:SF46 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;non-canonical Wnt signaling pathway#GO:0035567;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>sFRP#P01434 MONDO|Ensembl=ENSMODG00000000991.4|UniProtKB=F7EAA4 F7EAA4 CLPTM1L PTHR21347:SF0 CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED LIPID SCRAMBLASE CLPTM1L membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000043621.1|UniProtKB=A0A5F8GYS1 A0A5F8GYS1 NKX3-2 PTHR24340:SF34 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-3.2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000007156.4|UniProtKB=F6RDB9 F6RDB9 ACAT2 PTHR18919:SF107 ACETYL-COA C-ACYLTRANSFERASE ACETYL-COA ACETYLTRANSFERASE, CYTOSOLIC acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000041971.1|UniProtKB=A0A5F8H6V4 A0A5F8H6V4 FAM177B PTHR31206:SF9 LP10445P PROTEIN FAM177B MONDO|Ensembl=ENSMODG00000019614.4|UniProtKB=F6Y6W8 F6Y6W8 TLR4 PTHR24365:SF521 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 4 binding#GO:0005488;carbohydrate derivative binding#GO:0097367;lipopolysaccharide binding#GO:0001530;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;lipid binding#GO:0008289 response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101;response to lipid#GO:0033993;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to lipopolysaccharide#GO:0032496;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;defense response to Gram-negative bacterium#GO:0050829;response to stimulus#GO:0050896;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;detection of chemical stimulus#GO:0009593;immune response-regulating signaling pathway#GO:0002764;toll-like receptor signaling pathway#GO:0002224;response to oxygen-containing compound#GO:1901700;defense response to bacterium#GO:0042742;immune system process#GO:0002376;toll-like receptor 4 signaling pathway#GO:0034142;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;detection of stimulus#GO:0051606;activation of innate immune response#GO:0002218;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;regulation of innate immune response#GO:0045088;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;response to external biotic stimulus#GO:0043207;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;cell communication#GO:0007154;regulation of immune response#GO:0050776;inflammatory response#GO:0006954;regulation of defense response#GO:0031347;response to bacterium#GO:0009617 membrane#GO:0016020;membrane protein complex#GO:0098796;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR2,4,7#P01351;Toll receptor signaling pathway#P00054>TLR#P01346;Toll receptor signaling pathway#P00054>TLR4#P01339 MONDO|Ensembl=ENSMODG00000041872.1|UniProtKB=F7AYN7 F7AYN7 PTHR11426:SF256 HISTONE H3 HISTONE H3 cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;mitotic metaphase chromosome alignment#GO:0007080;protein-containing complex assembly#GO:0065003;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;organelle assembly#GO:0070925;organelle localization#GO:0051640;nuclear division#GO:0000280;kinetochore assembly#GO:0051382;localization#GO:0051179;kinetochore organization#GO:0051383;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000007732.4|UniProtKB=F7C485 F7C485 EEF2K PTHR45992:SF12 EUKARYOTIC ELONGATION FACTOR 2 KINASE-RELATED EUKARYOTIC ELONGATION FACTOR 2 KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;calcium/calmodulin-dependent protein kinase activity#GO:0004683;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794;cell junction#GO:0030054;postsynaptic density#GO:0014069 Oxidative stress response#P00046>eEF2K#P01127;p38 MAPK pathway#P05918>eEF2K#P06022 MONDO|Ensembl=ENSMODG00000027983.2|UniProtKB=A0A5F8GI51 A0A5F8GI51 PTHR10339:SF2 ADP-RIBOSYLTRANSFERASE ECTO-ADP-RIBOSYLTRANSFERASE 5 pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 transferase#PC00220 MONDO|Ensembl=ENSMODG00000008005.4|UniProtKB=F7CLH4 F7CLH4 ADHFE1 PTHR11496:SF83 ALCOHOL DEHYDROGENASE HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000024377.2|UniProtKB=F6ZSM9 F6ZSM9 PTHR48002:SF45 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012420.4|UniProtKB=A0A5F8GXK4 A0A5F8GXK4 CACNA2D3 PTHR10166:SF25 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-3 gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 calcium channel complex#GO:0034704;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 voltage-gated ion channel#PC00241;transporter#PC00227 MONDO|Ensembl=ENSMODG00000036601.1|UniProtKB=A0A5F8GXW4 A0A5F8GXW4 RWDD1 PTHR12292:SF9 RWD DOMAIN-CONTAINING PROTEIN RWD DOMAIN-CONTAINING PROTEIN 1 response to steroid hormone#GO:0048545;cellular response to chemical stimulus#GO:0070887;intracellular signal transduction#GO:0035556;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;steroid hormone receptor signaling pathway#GO:0043401;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;intracellular receptor signaling pathway#GO:0030522;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to steroid hormone stimulus#GO:0071383;cellular process#GO:0009987;signal transduction#GO:0007165;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;response to hormone#GO:0009725;biological regulation#GO:0065007;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;nuclear receptor-mediated signaling pathway#GO:0141193;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000041092.1|UniProtKB=A0A5F8G6W7 A0A5F8G6W7 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001502.5|UniProtKB=F7F4H1 F7F4H1 TAL1 PTHR13864:SF16 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000045784.1|UniProtKB=A0A5F8H749 A0A5F8H749 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000023322.1|UniProtKB=F6Y6H3 F6Y6H3 LOC103093560 PTHR15825:SF5 UBIQUITIN-FOLD MODIFIER 1 UBIQUITIN-FOLD MODIFIER 1 process utilizing autophagic mechanism#GO:0061919;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;macroautophagy#GO:0016236;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;autophagy#GO:0006914;response to stress#GO:0006950;reticulophagy#GO:0061709 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000006664.4|UniProtKB=A0A5F8HDY1 A0A5F8HDY1 PYGM PTHR11468:SF32 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE, MUSCLE FORM hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;polysaccharide catabolic process#GO:0000272;polysaccharide metabolic process#GO:0005976;catabolic process#GO:0009056;glucan catabolic process#GO:0009251;carbohydrate metabolic process#GO:0005975;energy reserve metabolic process#GO:0006112;carbohydrate catabolic process#GO:0016052;glycogen catabolic process#GO:0005980;cellular process#GO:0009987;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 transferase#PC00220;glycosyltransferase#PC00111 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase a#P00718;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b#P00717 MONDO|Ensembl=ENSMODG00000008870.4|UniProtKB=F7CAY9 F7CAY9 HAT1 PTHR12046:SF0 HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000040312.1|UniProtKB=A0A5F8GIP7 A0A5F8GIP7 ICAM5 PTHR13771:SF19 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 5 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155;leukocyte cell-cell adhesion#GO:0007159;cell adhesion mediated by integrin#GO:0033627 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000000996.4|UniProtKB=F7E9P7 F7E9P7 PPFIA4 PTHR12587:SF5 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA-4 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical structure#GO:0110165;presynaptic active zone#GO:0048786;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000025566.3|UniProtKB=F6UHS6 F6UHS6 PTHR37349:SF1 TESTIS-EXPRESSED PROTEIN 12 TESTIS-EXPRESSED PROTEIN 12 homologous chromosome pairing at meiosis#GO:0007129;cellular component assembly#GO:0022607;synaptonemal complex assembly#GO:0007130;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;meiotic nuclear division#GO:0140013;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;reproductive process#GO:0022414;cell cycle process#GO:0022402;cell cycle#GO:0007049;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;meiosis I#GO:0007127;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280 intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;synaptonemal structure#GO:0099086;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;central element#GO:0000801;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000014983.3|UniProtKB=H9H6Q8 H9H6Q8 PTHR48051:SF39 FAMILY NOT NAMED LEUCINE RICH REPEAT CONTAINING 27 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000013951.4|UniProtKB=F7C3I7 F7C3I7 PTHR13264:SF5 GCIP-INTERACTING PROTEIN P29 PRE-MRNA-SPLICING FACTOR SYF2 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000016137.4|UniProtKB=F7DRV3 F7DRV3 DDX56 PTHR24031:SF781 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX56-RELATED response to virus#GO:0009615;rRNA processing#GO:0006364;RNA biosynthetic process#GO:0032774;response to external biotic stimulus#GO:0043207;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;response to external stimulus#GO:0009605;defense response#GO:0006952;rRNA metabolic process#GO:0016072;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;response to other organism#GO:0051707;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;ribonucleoprotein complex biogenesis#GO:0022613;defense response to virus#GO:0051607;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;response to biotic stimulus#GO:0009607;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;cellular process#GO:0009987 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000000734.4|UniProtKB=F6W5H0 F6W5H0 MMP3 PTHR10201:SF215 MATRIX METALLOPROTEINASE STROMELYSIN-1 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 catabolic process#GO:0009056;cellular process#GO:0009987;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152;extracellular structure organization#GO:0043062 metalloprotease#PC00153 CCKR signaling map#P06959>MMP3#P07105;Plasminogen activating cascade#P00050>pro-MMP-3#P01260;Plasminogen activating cascade#P00050>MMP-3#P01251 MONDO|Ensembl=ENSMODG00000007972.5|UniProtKB=F7DQQ1 F7DQQ1 LOC100018720 PTHR24300:SF84 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450, FAMILY 2, SUBFAMILY T, POLYPEPTIDE 4 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;tetrapyrrole binding#GO:0046906;binding#GO:0005488 cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;cellular response to xenobiotic stimulus#GO:0071466;icosanoid metabolic process#GO:0006690;response to chemical#GO:0042221;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;olefinic compound metabolic process#GO:0120254;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000008193.4|UniProtKB=F6PFR8 F6PFR8 WRNIP1 PTHR13779:SF7 WERNER HELICASE-INTERACTING PROTEIN 1 FAMILY MEMBER ATPASE WRNIP1 DNA helicase activity#GO:0003678;molecular function regulator activity#GO:0098772;isomerase activity#GO:0016853;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;enzyme activator activity#GO:0008047;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;molecular function activator activity#GO:0140677;ATP-dependent activity, acting on DNA#GO:0008094;enzyme regulator activity#GO:0030234;ATP-dependent activity#GO:0140657 DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009;DNA helicase#PC00011 MONDO|Ensembl=ENSMODG00000018027.5|UniProtKB=A0A5F8HFZ4 A0A5F8HFZ4 ATG5 PTHR13040:SF2 AUTOPHAGY PROTEIN 5 AUTOPHAGY PROTEIN 5 ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity, acting on a protein#GO:0140096 autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;organelle organization#GO:0006996;response to stress#GO:0006950;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;cellular response to nutrient levels#GO:0031669;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;autophagy of mitochondrion#GO:0000422;autophagosome assembly#GO:0000045;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;cellular component organization#GO:0016043;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;organelle assembly#GO:0070925;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919 catalytic complex#GO:1902494;transferase complex#GO:1990234;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000018354.3|UniProtKB=F6PQH4 F6PQH4 FKBP4 PTHR10516:SF25 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP4 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;cis-trans isomerase activity#GO:0016859;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000001590.2|UniProtKB=F7BBC6 F7BBC6 PTHR45809:SF1 VIRAL IAP-ASSOCIATED FACTOR HOMOLOG PHOSDUCIN-LIKE PROTEIN 2 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000029274.2|UniProtKB=K7E1I1 K7E1I1 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED RETROVIRAL ENVELOPE PROTEIN GP41-LIKE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000040676.1|UniProtKB=A0A5F8H539 A0A5F8H539 MARCKSL1 PTHR14353:SF8 MYRISTOYLATED ALANINE-RICH C-KINASE SUBSTRATE MARCKS MARCKS-RELATED PROTEIN actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 anatomical structure development#GO:0048856;system development#GO:0048731;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;central nervous system development#GO:0007417;cellular component organization#GO:0016043;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000012035.3|UniProtKB=F7ALP4 F7ALP4 CDC7 PTHR11909:SF7 CASEIN KINASE-RELATED CELL DIVISION CYCLE 7-RELATED PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000041434.1|UniProtKB=A0A5F8HBK0 A0A5F8HBK0 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000048407.1|UniProtKB=A0A5F8GCL9 A0A5F8GCL9 PTHR12035:SF125 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 5 organic acid binding#GO:0043177;carbohydrate derivative binding#GO:0097367;ion binding#GO:0043167;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000041655.1|UniProtKB=A0A5F8HFP7 A0A5F8HFP7 LOC100021543 PTHR26450:SF43 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000050051.1|UniProtKB=A0A5F8GP08 A0A5F8GP08 LOC100028601 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007001.4|UniProtKB=F6XUJ9 F6XUJ9 PTHR31671:SF0 DIABETES AND OBESITY REGULATED, ISOFORM G TUMOR PROTEIN P53-INDUCIBLE NUCLEAR PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713;protein-membrane adaptor activity#GO:0043495 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;process utilizing autophagic mechanism#GO:0061919;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;organelle assembly#GO:0070925;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;vacuole organization#GO:0007033;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;macroautophagy#GO:0016236;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000023034.2|UniProtKB=F6S168 F6S168 PTHR13947:SF48 GNAT FAMILY N-ACETYLTRANSFERASE N-ACETYLTRANSFERASE 8-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000036706.1|UniProtKB=A0A5F8GG34 A0A5F8GG34 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000045571.1|UniProtKB=A0A5F8GXN9 A0A5F8GXN9 PTHR15561:SF0 CALCITONIN GENE-RELATED PEPTIDE-RECEPTOR COMPONENT PROTEIN DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC9 transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000041784.1|UniProtKB=A0A5F8GHI9 A0A5F8GHI9 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000040138.1|UniProtKB=A0A5F8G4M7 A0A5F8G4M7 LOC107648874 PTHR24384:SF253 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 502 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000017914.4|UniProtKB=F7F2R5 F7F2R5 SLC16A10 PTHR11360:SF119 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 10 transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;localization#GO:0051179;establishment of localization#GO:0051234;regulation of hormone levels#GO:0010817;transport#GO:0006810;hormone transport#GO:0009914 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944 transporter#PC00227 MONDO|Ensembl=ENSMODG00000048748.1|UniProtKB=A0A5F8GBZ4 A0A5F8GBZ4 PTHR11960:SF17 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 2 translation factor activity#GO:0180051;binding#GO:0005488;nucleic acid binding#GO:0003676;translation initiation factor activity#GO:0003743;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000010459.4|UniProtKB=A0A5F8GY49 A0A5F8GY49 SLC4A5 PTHR11453:SF137 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN bicarbonate transmembrane transporter activity#GO:0015106;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324 intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;localization#GO:0051179;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000014359.3|UniProtKB=F6U4Q1 F6U4Q1 TREX1 PTHR13058:SF27 THREE PRIME REPAIR EXONUCLEASE 1, 2 THREE-PRIME REPAIR EXONUCLEASE 1 DNA exonuclease activity#GO:0004529;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;hydrolase activity#GO:0016787 macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;DNA catabolic process#GO:0006308;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000016201.4|UniProtKB=F6PYG5 F6PYG5 LOC100009949 PTHR23226:SF127 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 24 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011916.4|UniProtKB=F7E028 F7E028 HNRNPDL PTHR48033:SF2 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D-LIKE RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;chromosome#GO:0005694;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000043748.1|UniProtKB=A0A5F8HK62 A0A5F8HK62 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000020560.4|UniProtKB=F7AQ06 F7AQ06 CHRNA9 PTHR18945:SF489 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-9 molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215 establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;transport#GO:0006810;synaptic transmission, cholinergic#GO:0007271;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic signaling#GO:0099536;cellular process#GO:0009987;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052;membrane depolarization#GO:0051899;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088 MONDO|Ensembl=ENSMODG00000025623.3|UniProtKB=F6XWW6 F6XWW6 TMEM14C PTHR12668:SF4 TRANSMEMBRANE PROTEIN 14, 15 TRANSMEMBRANE PROTEIN 14C-RELATED cellular process#GO:0009987;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;tetrapyrrole biosynthetic process#GO:0033014;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound biosynthetic process#GO:0006779 mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000002056.3|UniProtKB=F6V087 F6V087 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019680.4|UniProtKB=F6TTE4 F6TTE4 PTHR11232:SF76 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER CARBOXYL-TERMINAL PDZ LIGAND OF NEURONAL NITRIC OXIDE SYNTHASE PROTEIN signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000011114.4|UniProtKB=F7BBH4 F7BBH4 OPN4 PTHR24240:SF72 OPSIN MELANOPSIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;detection of stimulus#GO:0051606;cellular process#GO:0009987;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;signal transduction#GO:0007165;regulation of circadian rhythm#GO:0042752;cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to radiation#GO:0071478;signaling#GO:0023052;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000012665.4|UniProtKB=A0A5F8HE29 A0A5F8HE29 SPAG9 PTHR13886:SF2 JNK/SAPK-ASSOCIATED PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 4 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;kinase binding#GO:0019900;binding#GO:0005488;structural molecule activity#GO:0005198;MAP kinase scaffold activity#GO:0005078;cytoskeletal protein binding#GO:0008092;protein complex scaffold activity#GO:0140378;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000027408.2|UniProtKB=K7E2G3 K7E2G3 LOC103104732 PTHR46490:SF3 C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER A-RELATED KILLER CELL LECTIN-LIKE RECEPTOR 8 ISOFORM X1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000044728.1|UniProtKB=A0A5F8GRQ9 A0A5F8GRQ9 PROSER2 PTHR16095:SF9 TRANSMEMBRANE PROTEIN 143 FAMILY MEMBER PROLINE AND SERINE-RICH PROTEIN 2 MONDO|Ensembl=ENSMODG00000024503.1|UniProtKB=F7B7G9 F7B7G9 LOC100030989 PTHR19424:SF3 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR-BINDING PROTEIN 1 cellular response to stress#GO:0033554;response to temperature stimulus#GO:0009266;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to heat#GO:0009408;cellular response to heat#GO:0034605;heat acclimation#GO:0010286;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000007139.4|UniProtKB=A0A5F8GHZ3 A0A5F8GHZ3 SMG7 PTHR15696:SF5 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG7 telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000004895.4|UniProtKB=A0A5F8H8S7 A0A5F8H8S7 GDPD2 PTHR23344:SF1 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 3 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000043415.1|UniProtKB=A0A5F8G976 A0A5F8G976 RAB17 PTHR24073:SF912 DRAB5-RELATED RAS-RELATED PROTEIN RAB-17 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 endocytosis#GO:0006897;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;import into cell#GO:0098657;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 endocytic vesicle#GO:0030139;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000037699.1|UniProtKB=K7E601 K7E601 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED RETROVIRAL ENVELOPE PROTEIN GP41-LIKE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000004979.4|UniProtKB=K7E662 K7E662 PRDM10 PTHR24403:SF48 ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 10 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000041667.1|UniProtKB=A0A5F8HD31 A0A5F8HD31 PTHR12817:SF3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;cis-Golgi network#GO:0005801;Golgi apparatus#GO:0005794;trans-Golgi network#GO:0005802;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000040974.1|UniProtKB=K7E095 K7E095 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000004427.3|UniProtKB=F6SCI4 F6SCI4 KLHDC4 PTHR46063:SF1 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 4 MONDO|Ensembl=ENSMODG00000008019.4|UniProtKB=F7CL14 F7CL14 NDEL1 PTHR10921:SF0 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 NUCLEAR DISTRIBUTION PROTEIN NUDE-LIKE 1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 transport#GO:0006810;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;regulation of cell projection organization#GO:0031344;microtubule polymerization#GO:0046785;vesicle cytoskeletal trafficking#GO:0099518;mitotic cell cycle process#GO:1903047;establishment of mitotic spindle orientation#GO:0000132;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;regulation of plasma membrane bounded cell projection organization#GO:0120035;establishment of spindle localization#GO:0051293;vesicle localization#GO:0051648;microtubule polymerization or depolymerization#GO:0031109;biological regulation#GO:0065007;cell migration#GO:0016477;cytoskeleton-dependent intracellular transport#GO:0030705;organelle localization#GO:0051640;supramolecular fiber organization#GO:0097435;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;establishment of cell polarity#GO:0030010;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;microtubule-based movement#GO:0007018;cell motility#GO:0048870;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;chromosome segregation#GO:0007059;establishment of spindle orientation#GO:0051294;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;establishment of localization in cell#GO:0051649;establishment of mitotic spindle localization#GO:0040001;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;chromosome localization#GO:0050000;organelle transport along microtubule#GO:0072384;cytoskeleton organization#GO:0007010;establishment of vesicle localization#GO:0051650;cellular component assembly#GO:0022607;microtubule-based transport#GO:0099111;nuclear division#GO:0000280;establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;spindle localization#GO:0051653;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;regulation of biological process#GO:0050789;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;microtubule nucleation#GO:0007020;centrosome localization#GO:0051642;establishment of organelle localization#GO:0051656;regulation of cellular component organization#GO:0051128 membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;kinetochore#GO:0000776 MONDO|Ensembl=ENSMODG00000012859.3|UniProtKB=F7C969 F7C969 OR10G6 PTHR26453:SF179 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G6 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003829.3|UniProtKB=F7GJE2 F7GJE2 DMRTA1 PTHR12322:SF71 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR A1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;sex differentiation#GO:0007548;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000042457.1|UniProtKB=A8E6E5 A8E6E5 IFN2 PTHR11691:SF37 TYPE I INTERFERON INTERFERON OMEGA-1 binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cell activation#GO:0001775;cytokine-mediated signaling pathway#GO:0019221;biological regulation#GO:0065007;response to other organism#GO:0051707;adaptive immune response#GO:0002250;multicellular organismal process#GO:0032501;immune response#GO:0006955;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;T cell activation#GO:0042110;cell activation involved in immune response#GO:0002263;response to peptide#GO:1901652;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;B cell activation involved in immune response#GO:0002312;T cell activation involved in immune response#GO:0002286;lymphocyte activation#GO:0046649;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;lymphocyte activation involved in immune response#GO:0002285;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;B cell activation#GO:0042113;immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;leukocyte activation involved in immune response#GO:0002366;natural killer cell activation#GO:0030101;humoral immune response#GO:0006959 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083;interferon superfamily#PC00127 MONDO|Ensembl=ENSMODG00000010581.3|UniProtKB=F7GI09 F7GI09 HTRA4 PTHR22939:SF105 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA4 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 positive regulation of apoptotic process#GO:0043065;macromolecule metabolic process#GO:0043170;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;protein metabolic process#GO:0019538;proteolysis#GO:0006508;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cell death#GO:0008219;regulation of programmed cell death#GO:0043067;primary metabolic process#GO:0044238;programmed cell death#GO:0012501 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000018164.4|UniProtKB=F7CCX9 F7CCX9 ATP6V1A PTHR43607:SF9 V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;monoatomic cation transmembrane transporter activity#GO:0008324 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987 membrane#GO:0016020;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;proton-transporting two-sector ATPase complex#GO:0016469;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;lysosome#GO:0005764;cation-transporting ATPase complex#GO:0090533;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000050878.1|UniProtKB=A0A5F8HKA0 A0A5F8HKA0 POLR2K PTHR12056:SF4 DNA-DIRECTED RNA POLYMERASES I, II, AND III DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC4 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;RNA polymerase I complex#GO:0005736;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 MONDO|Ensembl=ENSMODG00000003009.3|UniProtKB=A0A5F8GWF8 A0A5F8GWF8 THOC7 PTHR23405:SF5 MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED THO COMPLEX SUBUNIT 7 gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;localization#GO:0051179;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription export complex#GO:0000346;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000006239.4|UniProtKB=F7FS04 F7FS04 SULT4A1 PTHR11783:SF274 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4A1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000040870.1|UniProtKB=A0A5F8GDJ8 A0A5F8GDJ8 PTHR23411:SF49 TAPASIN NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3 LIGAND 1 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000042220.1|UniProtKB=A0A5F8GSE9 A0A5F8GSE9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000004852.4|UniProtKB=F6TPU3 F6TPU3 ACTR3B PTHR11937:SF514 ACTIN ACTIN-RELATED PROTEIN 3B protein binding#GO:0005515;protein-containing complex binding#GO:0044877;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;structural molecule activity#GO:0005198;cytoskeletal protein binding#GO:0008092 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cytoskeleton organization#GO:0007010;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;cortical actin cytoskeleton organization#GO:0030866;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000000817.3|UniProtKB=F6S9D9 F6S9D9 CREB3L3 PTHR45996:SF1 AGAP001464-PB CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713 MONDO|Ensembl=ENSMODG00000018848.4|UniProtKB=F7DWF6 F7DWF6 VPS72 PTHR13275:SF4 YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000009128.4|UniProtKB=F7EY52 F7EY52 FLT1 PTHR24416:SF390 TYROSINE-PROTEIN KINASE RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301 regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of locomotion#GO:0040017;positive regulation of MAPK cascade#GO:0043410;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;tube development#GO:0035295;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell migration#GO:0016477;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;sprouting angiogenesis#GO:0002040;positive regulation of signaling#GO:0023056;angiogenesis#GO:0001525;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;positive regulation of cell motility#GO:2000147;positive regulation of cell population proliferation#GO:0008284;vascular endothelial growth factor receptor signaling pathway#GO:0048010;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007957.4|UniProtKB=F7E9Y1 F7E9Y1 ELK3 PTHR11849:SF172 ETS ETS DOMAIN-CONTAINING PROTEIN ELK-3 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 Interleukin signaling pathway#P00036>ELK#P00962 MONDO|Ensembl=ENSMODG00000041015.1|UniProtKB=A0A5F8HE10 A0A5F8HE10 DAO PTHR11530:SF15 D-AMINO ACID OXIDASE D-AMINO-ACID OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 membrane-bounded organelle#GO:0043227;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 oxidase#PC00175 MONDO|Ensembl=ENSMODG00000016115.4|UniProtKB=F7EAU2 F7EAU2 PTHR11935:SF80 BETA LACTAMASE DOMAIN HYDROXYACYLGLUTATHIONE HYDROLASE, MITOCHONDRIAL hydrolase activity#GO:0016787;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000008085.4|UniProtKB=F6YJ26 F6YJ26 NXF1 PTHR10662:SF22 NUCLEAR RNA EXPORT FACTOR NUCLEAR RNA EXPORT FACTOR 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000008928.4|UniProtKB=A0A5F8GY17 A0A5F8GY17 LRRFIP1 PTHR19212:SF5 LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000029313.2|UniProtKB=K7E6A5 K7E6A5 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000016815.4|UniProtKB=F6VZ19 F6VZ19 BCAN PTHR22804:SF41 AGGRECAN/VERSICAN PROTEOGLYCAN BREVICAN CORE PROTEIN animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;system development#GO:0048731;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell periphery#GO:0071944;external encapsulating structure#GO:0030312;membrane#GO:0016020;extracellular matrix#GO:0031012;cell junction#GO:0030054;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 MONDO|Ensembl=ENSMODG00000011505.3|UniProtKB=F6V120 F6V120 C2orf42 PTHR13518:SF1 PUTATIVE TREBLE-CLEF ZINC-FINGER C2ORF42 FAMILY MEMBER RGD1306746 PROTEIN intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000023881.2|UniProtKB=F7FMY8 F7FMY8 POLR1D PTHR13946:SF28 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098 transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;transcription by RNA polymerase I#GO:0006360;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 MONDO|Ensembl=ENSMODG00000018388.3|UniProtKB=F6QUC7 F6QUC7 PTHR10902:SF0 60S RIBOSOMAL PROTEIN L35A LARGE RIBOSOMAL SUBUNIT PROTEIN EL33 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000044980.1|UniProtKB=A0A5F8GQZ9 A0A5F8GQZ9 ZNF513 PTHR24403:SF66 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 513 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025193.1|UniProtKB=F7C0I3 F7C0I3 IMP3 PTHR11831:SF1 30S 40S RIBOSOMAL PROTEIN U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP3 rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;structural constituent of ribosome#GO:0003735;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;ribosome#GO:0005840;small-subunit processome#GO:0032040;90S preribosome#GO:0030686;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000005534.3|UniProtKB=F7GJK6 F7GJK6 PLD2 PTHR18896:SF121 PHOSPHOLIPASE D PHOSPHOLIPASE D2 phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;hydrolase activity#GO:0016787 regulation of localization#GO:0032879;regulation of transport#GO:0051049;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biological regulation#GO:0065007;cellular process#GO:0009987;lipid catabolic process#GO:0016042;organophosphate metabolic process#GO:0019637;organophosphate catabolic process#GO:0046434;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 phospholipase#PC00186;lipase#PC00143 Angiogenesis#P00005>PLD#P00204;Parkinson disease#P00049>PLD2#P01207;Ras Pathway#P04393>PLD#P04574 MONDO|Ensembl=ENSMODG00000046254.1|UniProtKB=A0A5F8HG75 A0A5F8HG75 LOC100618085 PTHR38503:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 1 SMALL INTEGRAL MEMBRANE PROTEIN 1 homeostasis of number of cells#GO:0048872;developmental process#GO:0032502;immune system process#GO:0002376;multicellular organismal-level homeostasis#GO:0048871;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;erythrocyte differentiation#GO:0030218;cellular process#GO:0009987;homeostatic process#GO:0042592;hemopoiesis#GO:0030097;cell development#GO:0048468;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;myeloid cell differentiation#GO:0030099 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000036555.1|UniProtKB=A0A5F8H8N1 A0A5F8H8N1 LOC100028036 PTHR26452:SF310 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000012387.3|UniProtKB=F6PNE6 F6PNE6 DHRS3 PTHR24322:SF483 PKSB SHORT-CHAIN DEHYDROGENASE_REDUCTASE 3 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491 regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;terpenoid metabolic process#GO:0006721;regulation of intracellular signal transduction#GO:1902531;isoprenoid metabolic process#GO:0006720;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000027412.2|UniProtKB=K7E4R0 K7E4R0 PTHR11375:SF5 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER E molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;binding#GO:0005488;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;histone binding#GO:0042393;enzyme inhibitor activity#GO:0004857 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000004989.4|UniProtKB=F7FKH6 F7FKH6 F11 PTHR24253:SF44 TRANSMEMBRANE PROTEASE SERINE COAGULATION FACTOR XI serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 negative regulation of hemostasis#GO:1900047;proteolysis#GO:0006508;regulation of biological quality#GO:0065008;negative regulation of coagulation#GO:0050819;zymogen activation#GO:0031638;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of wound healing#GO:0061041;regulation of blood coagulation#GO:0030193;regulation of body fluid levels#GO:0050878;metabolic process#GO:0008152;negative regulation of response to wounding#GO:1903035;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of response to wounding#GO:1903034;negative regulation of response to external stimulus#GO:0032102;regulation of multicellular organismal process#GO:0051239;protein maturation#GO:0051604;gene expression#GO:0010467;regulation of response to external stimulus#GO:0032101;protein metabolic process#GO:0019538;negative regulation of multicellular organismal process#GO:0051241;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;negative regulation of blood coagulation#GO:0030195;regulation of response to stress#GO:0080134;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;regulation of hemostasis#GO:1900046;plasminogen activation#GO:0031639;negative regulation of wound healing#GO:0061045;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of coagulation#GO:0050818;negative regulation of response to stimulus#GO:0048585 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 Blood coagulation#P00011>FXIa#P00434;Blood coagulation#P00011>FXI#P00460 MONDO|Ensembl=ENSMODG00000038936.1|UniProtKB=A0A5F8GPP0 A0A5F8GPP0 APCS PTHR45869:SF5 C-REACTIVE PROTEIN-RELATED SERUM AMYLOID P-COMPONENT binding#GO:0005488;complement binding#GO:0001848;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;immune system process#GO:0002376;inflammatory response#GO:0006954;innate immune response#GO:0045087;defense response#GO:0006952;acute inflammatory response#GO:0002526;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000036374.1|UniProtKB=A0A5F8GIN5 A0A5F8GIN5 PTHR41694:SF8 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 11 POL PROTEIN-LIKE binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001816.5|UniProtKB=A0A5F8G7Q1 A0A5F8G7Q1 CBLB PTHR23007:SF3 CBL E3 UBIQUITIN-PROTEIN LIGASE CBL-B catalytic activity#GO:0003824;receptor tyrosine kinase binding#GO:0030971;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 membrane raft#GO:0045121;membrane#GO:0016020;membrane microdomain#GO:0098857;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ligase#PC00142 EGF receptor signaling pathway#P00018>c-Cbl#P00544 MONDO|Ensembl=ENSMODG00000017191.4|UniProtKB=F6XXP0 F6XXP0 GRPR PTHR45695:SF7 LEUCOKININ RECEPTOR-RELATED GASTRIN-RELEASING PEPTIDE RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016947.3|UniProtKB=A0A5F8H0E6 A0A5F8H0E6 HTR1F PTHR24247:SF34 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1F neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404 MONDO|Ensembl=ENSMODG00000051326.1|UniProtKB=A0A5F8H3I6 A0A5F8H3I6 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000014172.2|UniProtKB=F6U7C7 F6U7C7 POLR2I PTHR11239:SF1 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;transcription initiation at RNA polymerase II promoter#GO:0006367;response to stress#GO:0006950;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-excision repair#GO:0006289;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 MONDO|Ensembl=ENSMODG00000028312.2|UniProtKB=K7E360 K7E360 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000042552.1|UniProtKB=A0A5F8HC95 A0A5F8HC95 PTHR10010:SF23 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;phosphate transmembrane transporter activity#GO:0005315;symporter activity#GO:0015293 establishment of localization#GO:0051234;localization#GO:0051179;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;inorganic anion transport#GO:0015698;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;transport#GO:0006810;phosphate ion transport#GO:0006817;homeostatic process#GO:0042592 apical plasma membrane#GO:0016324;membrane#GO:0016020;vesicle#GO:0031982;brush border#GO:0005903;cell periphery#GO:0071944;plasma membrane region#GO:0098590;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical part of cell#GO:0045177;membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000008390.4|UniProtKB=F7BVD5 F7BVD5 NPTX2 PTHR19277:SF1 PENTRAXIN NEURONAL PENTRAXIN-2 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000009317.4|UniProtKB=F7GJU3 F7GJU3 TTC13 PTHR44523:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 13 TETRATRICOPEPTIDE REPEAT PROTEIN 13 MONDO|Ensembl=ENSMODG00000023965.2|UniProtKB=F7F6Y8 F7F6Y8 GPR135 PTHR22752:SF3 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 135 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000009586.4|UniProtKB=F7A9H2 F7A9H2 ERRFI1 PTHR14254:SF5 GENE 33 POLYPEPTIDE ERBB RECEPTOR FEEDBACK INHIBITOR 1 regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cell communication#GO:0010646;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of protein modification process#GO:0031399 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000042926.1|UniProtKB=A0A5F8G6W6 A0A5F8G6W6 PRRG4 PTHR24278:SF38 COAGULATION FACTOR TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 4 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000010941.4|UniProtKB=F7EP41 F7EP41 KIFC2 PTHR24115:SF479 KINESIN-RELATED KINESIN-LIKE PROTEIN KIFC2 ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657 mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;mitotic cell cycle#GO:0000278;microtubule-based movement#GO:0007018;mitotic spindle organization#GO:0007052;organelle assembly#GO:0070925;nuclear division#GO:0000280;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051 mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000009472.5|UniProtKB=F7FNT3 F7FNT3 ARID3B PTHR15348:SF3 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3B binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000038203.1|UniProtKB=A0A5F8H7V8 A0A5F8H7V8 HAPLN1 PTHR22804:SF10 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 1 multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;skeletal system development#GO:0001501;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;extracellular region#GO:0005576;cell junction#GO:0030054 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000002743.4|UniProtKB=A0A5F8GEI3 A0A5F8GEI3 NFAT5 PTHR12533:SF10 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS 5 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of macromolecule metabolic process#GO:0010604;intracellular signaling cassette#GO:0141124;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;calcium-mediated signaling#GO:0019722;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;calcineurin-NFAT signaling cascade#GO:0033173;calcineurin-mediated signaling#GO:0097720;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851 MONDO|Ensembl=ENSMODG00000044154.1|UniProtKB=A0A5F8HLC3 A0A5F8HLC3 monDomV1R1206 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013787.2|UniProtKB=F6TEW6 F6TEW6 IL1RN PTHR10078:SF28 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN growth factor binding#GO:0019838;protein binding#GO:0005515;signaling receptor inhibitor activity#GO:0030547;molecular function activator activity#GO:0140677;molecular function inhibitor activity#GO:0140678;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125;cytokine binding#GO:0019955;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cell surface receptor signaling pathway#GO:0007166;negative regulation of cytokine-mediated signaling pathway#GO:0001960;response to lipopolysaccharide#GO:0032496;regulation of cytokine-mediated signaling pathway#GO:0001959;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to stress#GO:0006950;regulation of response to cytokine stimulus#GO:0060759;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;negative regulation of signal transduction#GO:0009968;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;immune system process#GO:0002376;negative regulation of cell communication#GO:0010648;response to peptide#GO:1901652;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;negative regulation of biological process#GO:0048519;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;defense response#GO:0006952;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219;immune response#GO:0006955;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;inflammatory response#GO:0006954;response to bacterium#GO:0009617;cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;negative regulation of response to cytokine stimulus#GO:0060761;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;cytokine#PC00083;interleukin superfamily#PC00128 MONDO|Ensembl=ENSMODG00000021331.4|UniProtKB=H9H9L3 H9H9L3 PTHR43570:SF2 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE FAMILY 3 MEMBER B1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029 cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 MONDO|Ensembl=ENSMODG00000046696.1|UniProtKB=A0A5F8GMP9 A0A5F8GMP9 PTHR10903:SF182 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000029093.2|UniProtKB=K7DYR4 K7DYR4 PLA2G2D PTHR11716:SF57 PHOSPHOLIPASE A2 FAMILY MEMBER GROUP IID SECRETORY PHOSPHOLIPASE A2 calcium ion binding#GO:0005509;binding#GO:0005488;lipid binding#GO:0008289;metal ion binding#GO:0046872;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;A2-type glycerophospholipase activity#GO:0004623;carboxylic ester hydrolase activity#GO:0052689;ion binding#GO:0043167;small molecule binding#GO:0036094;lipase activity#GO:0016298;cation binding#GO:0043169;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phospholipid binding#GO:0005543 negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;primary metabolic process#GO:0044238;negative regulation of multicellular organismal process#GO:0051241;phospholipid metabolic process#GO:0006644;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;phosphatidylglycerol metabolic process#GO:0046471;regulation of T cell proliferation#GO:0042129;lipid metabolic process#GO:0006629;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cell activation#GO:0050866;negative regulation of cell population proliferation#GO:0008285;organophosphate metabolic process#GO:0019637;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;regulation of lymphocyte activation#GO:0051249;glycerolipid metabolic process#GO:0046486;metabolic process#GO:0008152;negative regulation of T cell proliferation#GO:0042130;regulation of leukocyte proliferation#GO:0070663;cellular process#GO:0009987;regulation of mononuclear cell proliferation#GO:0032944;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;regulation of T cell activation#GO:0050863;phosphatidylcholine metabolic process#GO:0046470;negative regulation of cell-cell adhesion#GO:0022408;glycerophospholipid metabolic process#GO:0006650 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000025456.3|UniProtKB=F6RK84 F6RK84 LOC103095126 PTHR22950:SF184 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID SYMPORTER 1 L-amino acid transmembrane transporter activity#GO:0015179;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;localization#GO:0051179;establishment of localization#GO:0051234;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;amino acid transporter#PC00046 MONDO|Ensembl=ENSMODG00000022796.2|UniProtKB=H9H937 H9H937 PTHR11224:SF37 MAKORIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE MAKORIN-1 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000012581.4|UniProtKB=F6PIY7 F6PIY7 BICD2 PTHR31233:SF7 BICAUDAL D FAMILY MEMBER PROTEIN BICAUDAL D HOMOLOG 2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 vesicle-mediated transport#GO:0016192;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;microtubule anchoring#GO:0034453;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule anchoring at microtubule organizing center#GO:0072393;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;protein localization to Golgi apparatus#GO:0034067;Golgi vesicle transport#GO:0048193;transport#GO:0006810;microtubule-based movement#GO:0007018;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;regulation of microtubule-based process#GO:0032886 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000044391.1|UniProtKB=A0A5F8GE00 A0A5F8GE00 PTHR28644:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 15 SMALL INTEGRAL MEMBRANE PROTEIN 15 MONDO|Ensembl=ENSMODG00000018307.3|UniProtKB=F6PVI2 F6PVI2 RARS2 PTHR11956:SF11 ARGINYL-TRNA SYNTHETASE ARGININE--TRNA LIGASE, MITOCHONDRIAL-RELATED ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000010640.4|UniProtKB=F7D4U6 F7D4U6 RBM10 PTHR13948:SF4 RNA-BINDING PROTEIN RNA-BINDING PROTEIN 10 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000020205.2|UniProtKB=F7FXV3 F7FXV3 MRPL16 PTHR12220:SF13 50S/60S RIBOSOMAL PROTEIN L16 LARGE RIBOSOMAL SUBUNIT PROTEIN UL16M structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843;binding#GO:0005488;nucleic acid binding#GO:0003676 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840 ribosomal protein#PC00202 Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005 MONDO|Ensembl=ENSMODG00000010673.4|UniProtKB=F7CJE9 F7CJE9 CRYBA4 PTHR11818:SF19 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN A4 structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;sensory perception#GO:0007600;nervous system process#GO:0050877;visual perception#GO:0007601;visual system development#GO:0150063;sensory perception of light stimulus#GO:0050953;multicellular organism development#GO:0007275;animal organ development#GO:0048513;system process#GO:0003008;sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;multicellular organismal process#GO:0032501;sensory system development#GO:0048880 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000007297.4|UniProtKB=F7FC68 F7FC68 LACTB2 PTHR23131:SF6 ENDORIBONUCLEASE LACTB2 ENDORIBONUCLEASE LACTB2 binding#GO:0005488;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;RNA binding#GO:0003723;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;single-stranded RNA binding#GO:0003727;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 endoribonuclease#PC00094;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000007825.3|UniProtKB=F7ETL0 F7ETL0 LOC100028801 PTHR48002:SF139 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K13 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006493.4|UniProtKB=F7D5E7 F7D5E7 PTHR46259:SF1 ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000019630.4|UniProtKB=F6XPU1 F6XPU1 MEGF9 PTHR10574:SF298 NETRIN/LAMININ-RELATED MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 9 cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;neuron development#GO:0048666;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;generation of neurons#GO:0048699;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;substrate adhesion-dependent cell spreading#GO:0034446;neuron differentiation#GO:0030182;cell motility#GO:0048870;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;cell-substrate adhesion#GO:0031589;system development#GO:0048731;external encapsulating structure organization#GO:0045229;multicellular organismal process#GO:0032501;cell migration#GO:0016477;extracellular matrix assembly#GO:0085029;tissue development#GO:0009888;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;basement membrane#GO:0005604;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 MONDO|Ensembl=ENSMODG00000011104.1|UniProtKB=F7BWV1 F7BWV1 PTHR11848:SF22 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 15 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP2/4/15#P06817;TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000002503.2|UniProtKB=F7B9Q6 F7B9Q6 TXNL4B PTHR12052:SF4 THIOREDOXIN-LIKE PROTEN 4A, 4B THIOREDOXIN-LIKE PROTEIN 4B RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000049416.1|UniProtKB=F7EI14 F7EI14 LOC100024173 PTHR48018:SF166 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M5 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023860.2|UniProtKB=F6X3D7 F6X3D7 PTHR12825:SF0 BNIP1-RELATED VESICLE TRANSPORT PROTEIN SEC20 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 cellular process#GO:0009987;transport#GO:0006810;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796 MONDO|Ensembl=ENSMODG00000037198.1|UniProtKB=A0A5F8HIJ5 A0A5F8HIJ5 PTHR38502:SF1 OVEREXPRESSED IN COLON CARCINOMA 1 PROTEIN OVEREXPRESSED IN COLON CARCINOMA 1 PROTEIN MONDO|Ensembl=ENSMODG00000004040.4|UniProtKB=F7CMA5 F7CMA5 IGHMBP2 PTHR43788:SF20 DNA2/NAM7 HELICASE FAMILY MEMBER DNA-BINDING PROTEIN SMUBP-2 macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 response to stress#GO:0006950;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000011675.4|UniProtKB=F7GEE8 F7GEE8 ALAS1 PTHR13693:SF50 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 5-AMINOLEVULINATE SYNTHASE, NON-SPECIFIC, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;protein metabolic process#GO:0019538;porphyrin-containing compound biosynthetic process#GO:0006779;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;primary metabolic process#GO:0044238;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;tetrapyrrole biosynthetic process#GO:0033014 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transaminase#PC00216 MONDO|Ensembl=ENSMODG00000007999.4|UniProtKB=F7D579 F7D579 PIGB PTHR22760:SF4 GLYCOSYLTRANSFERASE GPI ALPHA-1,2-MANNOSYLTRANSFERASE 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;gene expression#GO:0010467;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;biosynthetic process#GO:0009058;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;phospholipid metabolic process#GO:0006644 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000043890.1|UniProtKB=A0A5F8HIZ1 A0A5F8HIZ1 PTHR26452:SF125 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13A1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000020688.4|UniProtKB=F7DKI1 F7DKI1 LAMTOR3 PTHR13378:SF3 REGULATOR COMPLEX PROTEIN LAMTOR3 RAGULATOR COMPLEX PROTEIN LAMTOR3 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of TORC1 signaling#GO:1904263;regulation of TORC1 signaling#GO:1903432;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005856.4|UniProtKB=A0A5F8GGR9 A0A5F8GGR9 ENAH PTHR11202:SF1 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER PROTEIN ENABLED HOMOLOG binding#GO:0005488;protein binding#GO:0005515 neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular process#GO:0009987;anatomical structure development#GO:0048856;system development#GO:0048731;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;actin filament organization#GO:0007015;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;actin polymerization or depolymerization#GO:0008154 cell periphery#GO:0071944;membrane#GO:0016020;focal adhesion#GO:0005925;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 Axon guidance mediated by Slit/Robo#P00008>Mena#P00345;Cytoskeletal regulation by Rho GTPase#P00016>Ena/VASP#P00516;Axon guidance mediated by netrin#P00009>Ena#P00361 MONDO|Ensembl=ENSMODG00000041989.1|UniProtKB=A0A5F8HFU2 A0A5F8HFU2 LOC103103455 PTHR24376:SF38 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 544-RELATED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000016255.4|UniProtKB=F7C1X6 F7C1X6 CYP20A1 PTHR24280:SF4 CYTOCHROME P450 20A1 CYTOCHROME P450 20A1 oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000047917.1|UniProtKB=A0A5F8HI03 A0A5F8HI03 PTHR12817:SF3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus subcompartment#GO:0098791;TRAPP complex#GO:0030008;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;Golgi apparatus#GO:0005794;cis-Golgi network#GO:0005801;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535 MONDO|Ensembl=ENSMODG00000004177.4|UniProtKB=F6QNX2 F6QNX2 ZDHHC16 PTHR12246:SF28 PALMITOYLTRANSFERASE ZDHHC16 PALMITOYLTRANSFERASE ZDHHC16 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;circulatory system development#GO:0072359;heart development#GO:0007507;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;cellular response to stress#GO:0033554;developmental process#GO:0032502;DNA damage response#GO:0006974;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000007793.3|UniProtKB=F7A8L7 F7A8L7 LOC100028897 PTHR48002:SF55 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018789.3|UniProtKB=A0A5F8GVH0 A0A5F8GVH0 PTHR11431:SF47 FERRITIN FERRITIN LIGHT CHAIN cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;iron ion binding#GO:0005506;ferrous iron binding#GO:0008198 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 storage protein#PC00210 MONDO|Ensembl=ENSMODG00000005237.4|UniProtKB=F6ZBZ4 F6ZBZ4 ARL10 PTHR47575:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 10 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 10 MONDO|Ensembl=ENSMODG00000020644.4|UniProtKB=F7EMD8 F7EMD8 SGCB PTHR21142:SF2 SARCOGLYCANS BETA-SARCOGLYCAN membrane protein complex#GO:0098796;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;sarcolemma#GO:0042383 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000019232.4|UniProtKB=F6RE24 F6RE24 TMEM97 PTHR31204:SF1 SIGMA INTRACELLULAR RECEPTOR 2 SIGMA INTRACELLULAR RECEPTOR 2 regulation of cellular process#GO:0050794;regulation of localization#GO:0032879;regulation of transport#GO:0051049;biological regulation#GO:0065007;regulation of biological process#GO:0050789 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000019124.4|UniProtKB=F7EV47 F7EV47 MMP28 PTHR10201:SF298 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-28 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 MONDO|Ensembl=ENSMODG00000048946.1|UniProtKB=A0A5F8H0E3 A0A5F8H0E3 LOC100616819 PTHR24242:SF388 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000025734.2|UniProtKB=F6T243 F6T243 PTHR26454:SF53 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6J1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000029552.2|UniProtKB=A0A5F8GLJ0 A0A5F8GLJ0 PTHR23098:SF26 AGAP001331-PA-RELATED T-SNARE DOMAIN CONTAINING 1 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000002429.3|UniProtKB=F7E0E8 F7E0E8 PTHR11473:SF18 AROMATIC AMINO ACID HYDROXYLASE TYROSINE 3-MONOOXYGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 reproductive process#GO:0022414;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;phenol-containing compound metabolic process#GO:0018958;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;multicellular organismal reproductive process#GO:0048609;cell communication#GO:0007154;catecholamine metabolic process#GO:0006584;nervous system process#GO:0050877;cognition#GO:0050890;trans-synaptic signaling#GO:0099537;biogenic amine metabolic process#GO:0006576;cell-cell signaling#GO:0007267;biosynthetic process#GO:0009058;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;synaptic transmission, dopaminergic#GO:0001963;cellular process#GO:0009987;amine metabolic process#GO:0009308;synaptic signaling#GO:0099536;phenol-containing compound biosynthetic process#GO:0046189;system process#GO:0003008;metabolic process#GO:0008152 perikaryon#GO:0043204;intracellular anatomical structure#GO:0005622;axon#GO:0030424;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell body#GO:0044297 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Nicotine pharmacodynamics pathway#P06587>TH#P06614;Parkinson disease#P00049>TH#P01241;Adrenaline and noradrenaline biosynthesis#P00001>TH#P00062;Dopamine receptor mediated signaling pathway#P05912>TH#P05970 MONDO|Ensembl=ENSMODG00000005344.3|UniProtKB=F7CHP2 F7CHP2 SPATA19 PTHR36468:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 19, MITOCHONDRIAL SPERMATOGENESIS-ASSOCIATED PROTEIN 19, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;cilium#GO:0005929;9+2 motile cilium#GO:0097729;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;organelle#GO:0043226;motile cilium#GO:0031514 MONDO|Ensembl=ENSMODG00000004027.3|UniProtKB=F7D6F2 F7D6F2 HAO1 PTHR10578:SF151 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000038621.1|UniProtKB=A0A5F8GN05 A0A5F8GN05 MYCBP PTHR13168:SF0 ASSOCIATE OF C-MYC AMY-1 C-MYC-BINDING PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 PDGF signaling pathway#P00047>c-Myc#P01172 MONDO|Ensembl=ENSMODG00000027858.2|UniProtKB=K7E0T5 K7E0T5 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000011134.4|UniProtKB=A0A5F8G507 A0A5F8G507 ULK4 PTHR46240:SF1 SER/THR PROTEIN KINASE ULK4 INACTIVE SERINE_THREONINE-PROTEIN KINASE ULK4 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000007838.4|UniProtKB=F7ETC5 F7ETC5 COPS5 PTHR10410:SF6 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED COP9 SIGNALOSOME COMPLEX SUBUNIT 5 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 translation factor#PC00223;translation initiation factor#PC00224 PDGF signaling pathway#P00047>c-Jun#P01163 MONDO|Ensembl=ENSMODG00000004006.4|UniProtKB=A0A5F8HIV3 A0A5F8HIV3 CACNB4 PTHR11824:SF7 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-4 synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 voltage-gated ion channel#PC00241 Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411 MONDO|Ensembl=ENSMODG00000010373.4|UniProtKB=F6R3X2 F6R3X2 TRIB2 PTHR22961:SF15 SER/THR PROTEIN KINASE-TRB TRIBBLES HOMOLOG 2 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;protein binding#GO:0005515 positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of protein metabolic process#GO:0051247;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of metabolic process#GO:0009893;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000002491.4|UniProtKB=F7BVN1 F7BVN1 GPA33 PTHR44969:SF1 CELL SURFACE A33 ANTIGEN CELL SURFACE A33 ANTIGEN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000048450.1|UniProtKB=A0A5F8GMH2 A0A5F8GMH2 EEF1E1 PTHR44490:SF1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 enzyme activator activity#GO:0008047;kinase activator activity#GO:0019209;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 regulation of intracellular signal transduction#GO:1902531;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of cellular response to stress#GO:0080135;regulation of programmed cell death#GO:0043067;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;positive regulation of cell communication#GO:0010647;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of apoptotic process#GO:0043065;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 translation factor#PC00223;translation elongation factor#PC00222 MONDO|Ensembl=ENSMODG00000018721.3|UniProtKB=F7FBZ8 F7FBZ8 BAG2 PTHR12334:SF6 BAG FAMILY MOLECULAR CHAPERONE REGULATOR 2 BAG FAMILY MOLECULAR CHAPERONE REGULATOR 2 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000039929.1|UniProtKB=A0A5F8GB16 A0A5F8GB16 FAM3C PTHR14592:SF10 UNCHARACTERIZED FAM3 PROTEIN FAM3C signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000028223.2|UniProtKB=K7E5N7 K7E5N7 PTHR36687:SF2 GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2-RELATED GLUTAMATE RECEPTOR IONOTROPIC, DELTA-1 MONDO|Ensembl=ENSMODG00000047154.1|UniProtKB=A0A5F8HB35 A0A5F8HB35 OPHN1 PTHR12552:SF2 OLIGOPHRENIN 1 OLIGOPHRENIN-1 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 synaptic vesicle endocytosis#GO:0048488;negative regulation of protein metabolic process#GO:0051248;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;negative regulation of proteasomal protein catabolic process#GO:1901799;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;actin filament-based process#GO:0030029;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;regulation of synaptic transmission, glutamatergic#GO:0051966;localization#GO:0051179;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;synaptic vesicle recycling#GO:0036465;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;endocytosis#GO:0006897;regulation of cellular component organization#GO:0051128;regulation of signaling#GO:0023051;cellular localization#GO:0051641;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;regulation of protein metabolic process#GO:0051246;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840 dendritic spine#GO:0043197;actin cytoskeleton#GO:0015629;postsynapse#GO:0098794;neuron projection terminus#GO:0044306;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;distal axon#GO:0150034;terminal bouton#GO:0043195;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;axon#GO:0030424;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622;presynapse#GO:0098793;neuron projection#GO:0043005;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;axon terminus#GO:0043679;cell junction#GO:0030054;membraneless organelle#GO:0043228 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 MONDO|Ensembl=ENSMODG00000000423.4|UniProtKB=F6VAK8 F6VAK8 SEPSECS PTHR12944:SF2 SOLUBLE LIVER ANTIGEN/LIVER PANCREAS ANTIGEN O-PHOSPHOSERYL-TRNA(SEC) SELENIUM TRANSFERASE binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;tRNA binding#GO:0000049 regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;biological regulation#GO:0065007;translational elongation#GO:0006414;metabolic process#GO:0008152;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538 MONDO|Ensembl=ENSMODG00000017815.4|UniProtKB=F6ZXX3 F6ZXX3 RFX6 PTHR12619:SF28 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;chemical homeostasis#GO:0048878;developmental process#GO:0032502;regulation of gene expression#GO:0010468;glucose homeostasis#GO:0042593;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;carbohydrate homeostasis#GO:0033500;pancreas development#GO:0031016;regulation of biological process#GO:0050789;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000000709.4|UniProtKB=F6WL93 F6WL93 NMRK2 PTHR10285:SF143 URIDINE KINASE NICOTINAMIDE RIBOSIDE KINASE 2 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137;nucleotide kinase#PC00172 MONDO|Ensembl=ENSMODG00000042879.1|UniProtKB=K7E1J0 K7E1J0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007604.4|UniProtKB=F7C5R6 F7C5R6 EPC1 PTHR14898:SF6 ENHANCER OF POLYCOMB ENHANCER OF POLYCOMB HOMOLOG 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000049317.1|UniProtKB=A0A5F8HFF4 A0A5F8HFF4 PTHR37857:SF1 TRANSMEMBRANE PROTEIN 273 TRANSMEMBRANE PROTEIN 273 MONDO|Ensembl=ENSMODG00000008415.3|UniProtKB=F7G2J1 F7G2J1 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000018470.3|UniProtKB=F7CAJ6 F7CAJ6 LOC100022961 PTHR26452:SF930 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017551.3|UniProtKB=A0A5F8HFR5 A0A5F8HFR5 KHDRBS1 PTHR11208:SF30 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 1 RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143;binding#GO:0005488;mRNA binding#GO:0003729 regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000044052.1|UniProtKB=A0A5F8H400 A0A5F8H400 SLC25A15 PTHR45624:SF22 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL ORNITHINE TRANSPORTER 1 L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transmembrane transport#GO:1990542;cellular localization#GO:0051641;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000009402.3|UniProtKB=A0A5F8G8D3 A0A5F8G8D3 REEP1 PTHR12300:SF33 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;G protein-coupled receptor binding#GO:0001664;tubulin binding#GO:0015631;microtubule binding#GO:0008017;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;endoplasmic reticulum tubular network organization#GO:0071786;cellular component organization or biogenesis#GO:0071840 cytoplasmic microtubule#GO:0005881;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;endoplasmic reticulum tubular network#GO:0071782;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;organelle membrane#GO:0031090 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000000466.3|UniProtKB=F6URL5 F6URL5 PTHR11635:SF154 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN ribonucleotide binding#GO:0032553;protein kinase A binding#GO:0051018;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;kinase inhibitor activity#GO:0019210;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme inhibitor activity#GO:0004857;nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cell communication#GO:0007154 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554 protein-binding activity modulator#PC00095;kinase modulator#PC00140 MONDO|Ensembl=ENSMODG00000025338.3|UniProtKB=F6V1U4 F6V1U4 OLIG2 PTHR19290:SF32 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED OLIGODENDROCYTE TRANSCRIPTION FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;sensory organ development#GO:0007423;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000016657.4|UniProtKB=F7G770 F7G770 ARHGDIG PTHR10980:SF8 RHO GDP-DISSOCIATION INHIBITOR RHO GDP-DISSOCIATION INHIBITOR 3 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000040590.1|UniProtKB=F7GG98 F7GG98 LOC100012668 PTHR10366:SF364 NAD DEPENDENT EPIMERASE/DEHYDRATASE 3 BETA-HYDROXYSTEROID DEHYDROGENASE_DELTA 5--4-ISOMERASE TYPE 1 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;hormone metabolic process#GO:0042445;lipid biosynthetic process#GO:0008610;biological regulation#GO:0065007;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;steroid biosynthetic process#GO:0006694;regulation of biological quality#GO:0065008 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144;metabolite interconversion enzyme#PC00262 Androgen/estrogene/progesterone biosynthesis#P02727>3beta-Hydroxysteroid dehydrogenase#P02833 MONDO|Ensembl=ENSMODG00000000247.4|UniProtKB=A0A5F8GUX0 A0A5F8GUX0 SRC PTHR24418:SF53 TYROSINE-PROTEIN KINASE PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;non-membrane spanning protein tyrosine kinase activity#GO:0004715;binding#GO:0005488;signaling receptor binding#GO:0005102;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713 negative regulation of signal transduction#GO:0009968;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;response to hormone#GO:0009725;cellular response to steroid hormone stimulus#GO:0071383;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;hormone-mediated signaling pathway#GO:0009755;regulation of signaling#GO:0023051;cell adhesion#GO:0007155;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;epidermal growth factor receptor signaling pathway#GO:0007173;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;nuclear receptor-mediated signaling pathway#GO:0141193;ERBB signaling pathway#GO:0038127;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;intracellular receptor signaling pathway#GO:0030522;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of intrinsic apoptotic signaling pathway#GO:2001242;steroid hormone receptor signaling pathway#GO:0043401;regulation of extrinsic apoptotic signaling pathway#GO:2001236;intracellular signal transduction#GO:0035556;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to steroid hormone#GO:0048545 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 Cadherin signaling pathway#P00012>Src#P00468;CCKR signaling map#P06959>p62 SRC#P07047;Parkinson disease#P00049>Src kinase#P01230;Integrin signalling pathway#P00034>Src#P00940;Angiogenesis#P00005>Src#P00184;CCKR signaling map#P06959>p54 SRC#P07109;CCKR signaling map#P06959>SRC#P07202;CCKR signaling map#P06959>SRC @Galphaq#P07163;Gonadotropin-releasing hormone receptor pathway#P06664>SRC#P06844;CCKR signaling map#P06959>p60 SRC#P07207 MONDO|Ensembl=ENSMODG00000001245.3|UniProtKB=F7FWQ0 F7FWQ0 IFT52 PTHR12969:SF7 NGD5/OSM-6/IFT52 INTRAFLAGELLAR TRANSPORT PROTEIN 52 HOMOLOG cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;cellular component organization#GO:0016043;cilium assembly#GO:0060271;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intraciliary transport particle B#GO:0030992;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929 MONDO|Ensembl=ENSMODG00000010114.4|UniProtKB=F6X3Q8 F6X3Q8 RAD51B PTHR46456:SF2 DNA REPAIR PROTEIN RAD51 HOMOLOG 2 DNA REPAIR PROTEIN RAD51 HOMOLOG 2 DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;four-way junction DNA binding#GO:0000400;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 chromosome#GO:0005694;replication fork#GO:0005657;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000015375.5|UniProtKB=F6WH44 F6WH44 TTLL4 PTHR12241:SF162 TUBULIN POLYGLUTAMYLASE TUBULIN MONOGLUTAMYLASE TTLL4 catalytic activity, acting on a protein#GO:0140096;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;tubulin binding#GO:0015631;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515;binding#GO:0005488 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010 intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000048776.1|UniProtKB=A0A5F8H6S7 A0A5F8H6S7 monDomV1R1289 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024990.1|UniProtKB=F6U9H0 F6U9H0 SLITRK1 PTHR45773:SF7 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 1 positive regulation of cellular process#GO:0048522;axon development#GO:0061564;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;positive regulation of synapse assembly#GO:0051965;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell junction assembly#GO:1901888;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cellular component biogenesis#GO:0044089;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;regulation of synapse organization#GO:0050807;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;neuron development#GO:0048666 postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;glutamatergic synapse#GO:0098978;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;GABA-ergic synapse#GO:0098982;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000050161.1|UniProtKB=F6RKA3 F6RKA3 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000019381.4|UniProtKB=A0A5F8GSQ6 A0A5F8GSQ6 SH3GL3 PTHR14167:SF45 SH3 DOMAIN-CONTAINING ENDOPHILIN-A3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;cytoplasm#GO:0005737;cytosol#GO:0005829;presynapse#GO:0098793 scaffold/adaptor protein#PC00226 Huntington disease#P00029>SH3GL3#P00813 MONDO|Ensembl=ENSMODG00000044891.1|UniProtKB=A0A5F8H5B5 A0A5F8H5B5 C4orf46 PTHR31641:SF2 RENAL CANCER DIFFERENTIATION GENE 1 PROTEIN RENAL CANCER DIFFERENTIATION GENE 1 PROTEIN MONDO|Ensembl=ENSMODG00000038246.1|UniProtKB=A0A5F8GEB5 A0A5F8GEB5 PTHR23411:SF39 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;antigen binding#GO:0003823 defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;antibacterial humoral response#GO:0019731;immune effector process#GO:0002252;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;defense response to bacterium#GO:0042742;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;complement activation#GO:0006956;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;response to external biotic stimulus#GO:0043207;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;response to bacterium#GO:0009617 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000025128.2|UniProtKB=F6YS76 F6YS76 PTHR48188:SF2 60S RIBOSOMAL PROTEIN L43 LARGE RIBOSOMAL SUBUNIT PROTEIN EL43 cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000028425.2|UniProtKB=K7E5I7 K7E5I7 TNFRSF18 PTHR47388:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 18 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 18 positive regulation of cell adhesion#GO:0045785;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009861.6|UniProtKB=F6VVA1 F6VVA1 SLC24A1 PTHR10846:SF36 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 1 secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;antiporter activity#GO:0015297;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079 transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;regulation of synaptic plasticity#GO:0048167;negative regulation of cellular process#GO:0048523;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;localization#GO:0051179;metal ion transport#GO:0030001;modulation of chemical synaptic transmission#GO:0050804;homeostatic process#GO:0042592;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;chemical homeostasis#GO:0048878;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;inorganic ion homeostasis#GO:0098771;negative regulation of signaling#GO:0023057;positive regulation of synaptic transmission#GO:0050806;calcium ion homeostasis#GO:0055074;negative regulation of cell communication#GO:0010648;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;negative regulation of biological process#GO:0048519 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000013713.4|UniProtKB=F6Y9D5 F6Y9D5 PARP12 PTHR45740:SF6 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP12 pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000040582.1|UniProtKB=A0A5F8H8C1 A0A5F8H8C1 KLHDC9 PTHR47196:SF1 KELCH DOMAIN-CONTAINING PROTEIN 9 KELCH DOMAIN-CONTAINING PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;cyclin binding#GO:0030332 MONDO|Ensembl=ENSMODG00000006015.3|UniProtKB=A0A5F8GYI0 A0A5F8GYI0 CPT1B PTHR22589:SF69 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 1, MUSCLE ISOFORM catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;lipid metabolic process#GO:0006629;transport#GO:0006810;establishment of localization#GO:0051234;monocarboxylic acid metabolic process#GO:0032787;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carnitine metabolic process#GO:0009437;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876;fatty acid transport#GO:0015908;localization#GO:0051179;monocarboxylic acid transport#GO:0015718 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000002806.4|UniProtKB=F7BVU7 F7BVU7 PTHR24300:SF177 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2J2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;tetrapyrrole binding#GO:0046906;binding#GO:0005488 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000000915.4|UniProtKB=F6ZGV2 F6ZGV2 TMEM183A PTHR20988:SF2 TRANSMEMBRANE PROTEIN 183A-RELATED TRANSMEMBRANE PROTEIN 183A-RELATED SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000004718.4|UniProtKB=F6QGE8 F6QGE8 LINGO3 PTHR24373:SF130 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT AND IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING NOGO RECEPTOR-INTERACTING PROTEIN 3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023150.1|UniProtKB=F7GC32 F7GC32 SRP54 PTHR11564:SF40 SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54 SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54 nucleic acid binding#GO:0003676;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;RNA binding#GO:0003723;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;signal sequence receptor activity#GO:0005048;ribonucleoside triphosphate phosphatase activity#GO:0017111 establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;intracellular protein localization#GO:0008104;protein targeting to ER#GO:0045047;protein targeting to membrane#GO:0006612;intracellular transport#GO:0046907;protein transmembrane transport#GO:0071806;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of protein localization to endoplasmic reticulum#GO:0072599;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031;localization within membrane#GO:0051668;protein targeting#GO:0006605 cytosol#GO:0005829;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000007953.3|UniProtKB=F7G8T6 F7G8T6 DCTN3 PTHR28360:SF1 DYNACTIN SUBUNIT 3 DYNACTIN SUBUNIT 3 cytoskeleton-dependent cytokinesis#GO:0061640;cytokinesis#GO:0000910;cell cycle#GO:0007049;cell division#GO:0051301;cell cycle process#GO:0022402;cellular process#GO:0009987 protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000004083.4|UniProtKB=F6VW04 F6VW04 TMEM161A PTHR13624:SF4 RE42071P TRANSMEMBRANE PROTEIN 161A MONDO|Ensembl=ENSMODG00000001819.3|UniProtKB=F6T5K6 F6T5K6 RPS27A PTHR10666:SF530 UBIQUITIN POLYUBIQUITIN-C structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;nucleus#GO:0005634;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000016450.4|UniProtKB=F7A456 F7A456 B3GALT6 PTHR11214:SF410 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 6 glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosaminoglycan metabolic process#GO:0030203;aminoglycan biosynthetic process#GO:0006023;carbohydrate derivative biosynthetic process#GO:1901137;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule metabolic process#GO:0043170;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000009745.3|UniProtKB=F6X9G6 F6X9G6 CSTF3 PTHR19980:SF0 RNA CLEAVAGE STIMULATION FACTOR CLEAVAGE STIMULATION FACTOR SUBUNIT 3 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 mRNA polyadenylation factor#PC00146;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000017827.4|UniProtKB=F6ZXB4 F6ZXB4 EVA1B PTHR48422:SF2 PROTEIN EVA-1 HOMOLOG B-RELATED PROTEIN EVA-1 HOMOLOG B MONDO|Ensembl=ENSMODG00000024081.2|UniProtKB=F7BY57 F7BY57 PTHR21399:SF0 CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN METHYLOSOME SUBUNIT PICLN nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;cytosol#GO:0005829;spliceosomal complex#GO:0005681;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 transporter#PC00227 MONDO|Ensembl=ENSMODG00000005175.3|UniProtKB=F7E7G8 F7E7G8 LOC100619965 PTHR12867:SF6 GLYCOSYL TRANSFERASE-RELATED UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG13 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 transferase#PC00220 MONDO|Ensembl=ENSMODG00000001595.3|UniProtKB=F7BB95 F7BB95 TMEM263 PTHR31443:SF0 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 263 MONDO|Ensembl=ENSMODG00000047708.1|UniProtKB=A0A5F8G925 A0A5F8G925 PTHR16955:SF6 METASTASIS-SUPPRESSOR KISS-1 METASTASIS-SUPPRESSOR KISS-1 neuropeptide receptor binding#GO:0071855;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of system process#GO:0044057;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of hormone levels#GO:0010817;cellular response to stimulus#GO:0051716;regulation of hormone secretion#GO:0046883;cell communication#GO:0007154;regulation of secretion#GO:0051046;positive regulation of signaling#GO:0023056;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of hormone secretion#GO:0046887;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000016436.3|UniProtKB=F7ARW5 F7ARW5 CSTF1 PTHR44133:SF2 CLEAVAGE STIMULATION FACTOR SUBUNIT 1 CLEAVAGE STIMULATION FACTOR SUBUNIT 1 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000037707.1|UniProtKB=A0A5F8H5Y1 A0A5F8H5Y1 PTHR11904:SF12 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;purine-containing compound catabolic process#GO:0072523;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;nucleoside catabolic process#GO:0009164;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule catabolic process#GO:0034656;phosphorus metabolic process#GO:0006793;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;NAD+ metabolic process#GO:0019674;glycosyl compound catabolic process#GO:1901658;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;pyridine-containing compound metabolic process#GO:0072524;purine nucleoside metabolic process#GO:0042278;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 kinase#PC00137;nucleotide kinase#PC00172 Xanthine and guanine salvage pathway#P02788>Guanosine phosphorylase#P03250;Adenine and hypoxanthine salvage pathway#P02723>Deoxyinosine phosphorylase#P02812;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphorylase#P02805;Purine metabolism#P02769>Nucleoside Phosphorylase#P03115;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine phosphorylase#P02808;Adenine and hypoxanthine salvage pathway#P02723>Inosine phosphorylase#P02813;Xanthine and guanine salvage pathway#P02788>Deoxyguanosine phosphorylase#P03248 MONDO|Ensembl=ENSMODG00000043000.1|UniProtKB=A0A5F8H204 A0A5F8H204 LOC100024421 PTHR48018:SF10 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015024.3|UniProtKB=F7E640 F7E640 PTHR24012:SF409 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 1 mRNA binding#GO:0003729;poly(A) binding#GO:0008143;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;cytosol#GO:0005829 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000007242.3|UniProtKB=F6WBR7 F6WBR7 ANKS4B PTHR24161:SF20 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 4B cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;cellular process#GO:0009987;cellular component assembly#GO:0022607;protein localization to organelle#GO:0033365;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;membrane#GO:0016020;cell periphery#GO:0071944;actin-based cell projection#GO:0098858;microvillus#GO:0005902;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000045395.1|UniProtKB=A0A5F8GVY9 A0A5F8GVY9 PTHR48018:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001388.4|UniProtKB=F7FJ00 F7FJ00 ITGB8 PTHR10082:SF9 INTEGRIN BETA SUBUNIT INTEGRIN BETA-8 protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;signaling receptor binding#GO:0005102;binding#GO:0005488 cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;cellular process#GO:0009987;cell migration#GO:0016477;biological regulation#GO:0065007;cell adhesion mediated by integrin#GO:0033627;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;signaling#GO:0023052;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589 membrane protein complex#GO:0098796;membrane#GO:0016020;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;signaling receptor complex#GO:0043235;cell junction#GO:0030054;integrin complex#GO:0008305;anchoring junction#GO:0070161 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 MONDO|Ensembl=ENSMODG00000009825.3|UniProtKB=F6RX69 F6RX69 ATP6V1B2 PTHR43389:SF5 V-TYPE PROTON ATPASE SUBUNIT B V-TYPE PROTON ATPASE SUBUNIT B, BRAIN ISOFORM regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;proton transmembrane transport#GO:1902600;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;apical plasma membrane#GO:0016324;cation-transporting ATPase complex#GO:0090533;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;apical part of cell#GO:0045177;proton-transporting two-sector ATPase complex#GO:0016469;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068;ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000009501.4|UniProtKB=F7F9W9 F7F9W9 HSPA12A PTHR14187:SF46 ALPHA KINASE/ELONGATION FACTOR 2 KINASE HEAT SHOCK 70 KDA PROTEIN 12A MONDO|Ensembl=ENSMODG00000003289.3|UniProtKB=F7EYU6 F7EYU6 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000630.2|UniProtKB=F6TAE7 F6TAE7 LOC100009955 PTHR10157:SF31 DOPAMINE BETA HYDROXYLASE RELATED DBH-LIKE MONOOXYGENASE PROTEIN 2-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;secretory granule membrane#GO:0030667;intracellular vesicle#GO:0097708 hydroxylase#PC00122 MONDO|Ensembl=ENSMODG00000037835.1|UniProtKB=A0A5F8HJL8 A0A5F8HJL8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000023235.3|UniProtKB=A0A5F8G8A3 A0A5F8G8A3 LOC100033119 PTHR11177:SF248 CHITINASE OVIDUCT-SPECIFIC GLYCOPROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;chitin metabolic process#GO:0006030;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000039586.1|UniProtKB=A0A5F8GEH2 A0A5F8GEH2 PTHR23411:SF39 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 1-RELATED protein binding#GO:0005515;antigen binding#GO:0003823;binding#GO:0005488;signaling receptor binding#GO:0005102 adaptive immune response#GO:0002250;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;complement activation#GO:0006956;immune response#GO:0006955;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;response to external biotic stimulus#GO:0043207;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;response to bacterium#GO:0009617;defense response to other organism#GO:0098542;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;antibacterial humoral response#GO:0019731;immune effector process#GO:0002252;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;defense response to bacterium#GO:0042742;immune system process#GO:0002376 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000020365.4|UniProtKB=F7FJR1 F7FJR1 CAPSL PTHR34524:SF5 CALCYPHOSIN CALCYPHOSIN-LIKE PROTEIN calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000006175.4|UniProtKB=F7B510 F7B510 PTHR15431:SF9 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN CENTROSOMAL PROTEIN 43 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000019228.4|UniProtKB=F7FZ21 F7FZ21 NOS2 PTHR19384:SF56 NITRIC OXIDE SYNTHASE-RELATED NITRIC OXIDE SYNTHASE, INDUCIBLE oxidoreductase activity, acting on NAD(P)H#GO:0016651;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;monooxygenase activity#GO:0004497;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 blood circulation#GO:0008015;proteinogenic amino acid metabolic process#GO:0170039;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;biological regulation#GO:0065007;response to other organism#GO:0051707;amino acid metabolic process#GO:0006520;regulation of blood pressure#GO:0008217;carboxylic acid catabolic process#GO:0046395;response to external stimulus#GO:0009605;system process#GO:0003008;defense response#GO:0006952;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to bacterium#GO:0009617;circulatory system process#GO:0003013;inflammatory response#GO:0006954;response to chemical#GO:0042221;response to lipid#GO:0033993;arginine metabolic process#GO:0006525;intracellular signaling cassette#GO:0141124;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;metabolic process#GO:0008152;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;small molecule catabolic process#GO:0044282;response to endogenous stimulus#GO:0009719;carboxylic acid metabolic process#GO:0019752;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;oxoacid metabolic process#GO:0043436;defense response to bacterium#GO:0042742;response to oxygen-containing compound#GO:1901700 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 PI3 kinase pathway#P00048>NOS#P01205 MONDO|Ensembl=ENSMODG00000014092.4|UniProtKB=F6QJQ4 F6QJQ4 ZBTB9 PTHR46105:SF13 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 9 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000012136.3|UniProtKB=F7FU16 F7FU16 HYAL2 PTHR11769:SF6 HYALURONIDASE HYALURONIDASE-2 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;glycosaminoglycan catabolic process#GO:0006027 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000044832.1|UniProtKB=A0A5F8HBD4 A0A5F8HBD4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000042536.1|UniProtKB=A0A5F8HB93 A0A5F8HB93 LOC103100741 PTHR23226:SF127 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 24 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000039356.1|UniProtKB=A0A5F8HCW1 A0A5F8HCW1 PTHR10527:SF6 IMPORTIN BETA IMPORTIN-4 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 transporter#PC00227 MONDO|Ensembl=ENSMODG00000004479.4|UniProtKB=F7A8D5 F7A8D5 PTHR10372:SF8 PLAKOPHILLIN-RELATED PLAKOPHILIN-4 protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;cell-cell junction#GO:0005911;nucleus#GO:0005634;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;cell junction#GO:0030054;adherens junction#GO:0005912;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161 intermediate filament binding protein#PC00130;cytoskeletal protein#PC00085;intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000048339.1|UniProtKB=A0A5F8GJA0 A0A5F8GJA0 PTHR12151:SF4 ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER CYTOCHROME C OXIDASE ASSEMBLY FACTOR SCO1 mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108 oxidase#PC00175;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000009082.4|UniProtKB=A0A5F8GB11 A0A5F8GB11 PTHR10807:SF66 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR3 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;protein phosphatase binding#GO:0019903;phosphoric ester hydrolase activity#GO:0042578;enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902;hydrolase activity#GO:0016787;protein binding#GO:0005515 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;dephosphorylation#GO:0016311;lipid modification#GO:0030258 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000027477.2|UniProtKB=K7E579 K7E579 CLEC4G PTHR22802:SF245 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER G signaling receptor activity#GO:0038023;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;binding#GO:0005488 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000005552.4|UniProtKB=K7E4Z9 K7E4Z9 CDK9 PTHR24056:SF233 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 9 cyclin-dependent protein serine/threonine kinase activity#GO:0004693;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000047860.1|UniProtKB=A0A5F8GU79 A0A5F8GU79 LOC100010820 PTHR24302:SF38 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A5 steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000011825.4|UniProtKB=F7GM08 F7GM08 SEPTIN11 PTHR18884:SF48 SEPTIN SEPTIN-11 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;intracellular protein localization#GO:0008104;cytokinesis#GO:0000910;macromolecule localization#GO:0033036;cell cycle#GO:0007049;cell division#GO:0051301;cell cycle process#GO:0022402;cellular process#GO:0009987 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000001017.4|UniProtKB=F6ZFG5 F6ZFG5 BST1 PTHR10912:SF4 ADP-RIBOSYL CYCLASE ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE 2 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cyclase#PC00079;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000012704.4|UniProtKB=F6UY67 F6UY67 STAC2 PTHR15135:SF5 STAC SH3 AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN 2 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108 system process#GO:0003008;regulation of localization#GO:0032879;muscle contraction#GO:0006936;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of protein localization to membrane#GO:1905475;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of protein localization#GO:0032880;nervous system process#GO:0050877;neuromuscular process#GO:0050905;striated muscle contraction#GO:0006941;skeletal muscle contraction#GO:0003009;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;muscle system process#GO:0003012 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000008609.2|UniProtKB=A0A5F8GF41 A0A5F8GF41 CNOT8 PTHR10797:SF1 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 8 catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527 regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402 CCR4-NOT complex#GO:0030014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031;RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146 MONDO|Ensembl=ENSMODG00000019123.4|UniProtKB=F7EV55 F7EV55 TAF15 PTHR23238:SF25 RNA BINDING PROTEIN TATA-BINDING PROTEIN-ASSOCIATED FACTOR 2N RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000021065.3|UniProtKB=F6V201 F6V201 TMEM50B PTHR13180:SF0 SMALL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 50B retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197 vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 MONDO|Ensembl=ENSMODG00000051387.1|UniProtKB=A0A5F8HBK6 A0A5F8HBK6 PTHR42908:SF35 TRANSLATION ELONGATION FACTOR-RELATED ELONGATION FACTOR 2 GTPase activity#GO:0003924;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytosol#GO:0005829;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222 MONDO|Ensembl=ENSMODG00000016854.4|UniProtKB=F6QH33 F6QH33 UCMA PTHR28647:SF2 UNIQUE CARTILAGE MATRIX-ASSOCIATED PROTEIN UNIQUE CARTILAGE MATRIX-ASSOCIATED PROTEIN embryo development#GO:0009790;multicellular organismal process#GO:0032501;embryo development ending in birth or egg hatching#GO:0009792;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;system development#GO:0048731;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000039015.1|UniProtKB=A0A5F8GE22 A0A5F8GE22 LOC100024553 PTHR24399:SF80 ZINC FINGER AND BTB DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000002208.4|UniProtKB=A0A5F8H3R9 A0A5F8H3R9 IPP PTHR24412:SF35 KELCH PROTEIN ACTIN-BINDING PROTEIN IPP protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019898.4|UniProtKB=F6W5S4 F6W5S4 LRP4 PTHR24270:SF5 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 4 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transfer/carrier protein#PC00219;apolipoprotein#PC00052 Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112;Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173 MONDO|Ensembl=ENSMODG00000019053.3|UniProtKB=F7AXY2 F7AXY2 VPS37A PTHR13678:SF2 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A protein transport#GO:0015031;cellular localization#GO:0051641;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;intracellular protein transport#GO:0006886;protein targeting to membrane#GO:0006612;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;protein targeting to vacuole#GO:0006623;localization#GO:0051179;protein metabolic process#GO:0019538;localization within membrane#GO:0051668;protein localization to vacuole#GO:0072665;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;macromolecule localization#GO:0033036 ESCRT I complex#GO:0000813;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000044476.1|UniProtKB=F6SEW5 F6SEW5 PTHR24028:SF234 CADHERIN-87A PROTOCADHERIN GAMMA-A7 cell adhesion#GO:0007155;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000049807.1|UniProtKB=A0A5F8G4V9 A0A5F8G4V9 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017648.4|UniProtKB=A0A5F8HBG3 A0A5F8HBG3 PI4KA PTHR10048:SF15 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE ALPHA phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 kinase#PC00137 MONDO|Ensembl=ENSMODG00000001981.4|UniProtKB=A0A5F8GNZ9 A0A5F8GNZ9 PTHR13035:SF0 PROTEIN N-TERMINAL GLUTAMINE AMIDOHYDROLASE PROTEIN N-TERMINAL GLUTAMINE AMIDOHYDROLASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000023253.3|UniProtKB=F6X8N3 F6X8N3 SPO11 PTHR10848:SF0 MEIOTIC RECOMBINATION PROTEIN SPO11 MEIOTIC RECOMBINATION PROTEIN SPO11 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 cell cycle process#GO:0022402;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;meiosis I#GO:0007127;response to stimulus#GO:0050896;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;cellular process#GO:0009987;response to stress#GO:0006950;meiotic DNA double-strand break formation#GO:0042138;organelle organization#GO:0006996;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;homologous recombination#GO:0035825;reproductive process#GO:0022414;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA repair#GO:0006281;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 endodeoxyribonuclease#PC00093 MONDO|Ensembl=ENSMODG00000015316.4|UniProtKB=F6XYC7 F6XYC7 GPR37 PTHR46216:SF3 PROSAPOSIN RECEPTOR GPR37 FAMILY MEMBER PROSAPOSIN RECEPTOR GPR37 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;positive regulation of MAPK cascade#GO:0043410;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 G-protein coupled receptor#PC00021 Parkinson disease#P00049>Pael-R#P01229 MONDO|Ensembl=ENSMODG00000025604.3|UniProtKB=F6QC26 F6QC26 C3H18orf54 PTHR35079:SF1 LUNG ADENOMA SUSCEPTIBILITY PROTEIN 2 LUNG ADENOMA SUSCEPTIBILITY PROTEIN 2 MONDO|Ensembl=ENSMODG00000043445.1|UniProtKB=A0A5F8H0G6 A0A5F8H0G6 PTHR19343:SF13 T CELL RECEPTOR ALPHA VARIABLE 1-2 IG-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000017154.4|UniProtKB=F6QE29 F6QE29 RSBN1L PTHR13354:SF9 ROUND SPERMATID BASIC PROTEIN 1 LYSINE-SPECIFIC DEMETHYLASE RSBN1L protein demethylase activity#GO:0140457;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000009319.3|UniProtKB=F7GJT4 F7GJT4 NANOS1 PTHR12887:SF18 NANOS PROTEIN NANOS HOMOLOG 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of protein metabolic process#GO:0051248;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;oogenesis#GO:0048477;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of translation#GO:0017148 cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000021352.4|UniProtKB=A0A5F8GAA5 A0A5F8GAA5 AVIL PTHR11977:SF33 VILLIN ADVILLIN phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;actin filament binding#GO:0051015;actin binding#GO:0003779;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of actin filament depolymerization#GO:0030834;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament polymerization#GO:0030833;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000041143.1|UniProtKB=A0A5F8HDN9 A0A5F8HDN9 KNCN PTHR38497:SF2 KINOCILIN KINOCILIN ISOFORM X1 MONDO|Ensembl=ENSMODG00000017895.4|UniProtKB=F6U8Z6 F6U8Z6 CLSPN PTHR14396:SF10 CLASPIN CLASPIN MONDO|Ensembl=ENSMODG00000041569.1|UniProtKB=A0A5F8GVJ0 A0A5F8GVJ0 MRPL52 PTHR34090:SF1 39S RIBOSOMAL PROTEIN L52, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML52 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000017948.5|UniProtKB=F6TSK1 F6TSK1 DLGAP3 PTHR12353:SF4 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 3 regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 postsynaptic specialization#GO:0099572;cell junction#GO:0030054;organelle#GO:0043226;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000021061.5|UniProtKB=F6YM38 F6YM38 SON PTHR46528:SF1 PROTEIN SON PROTEIN SON binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000015726.3|UniProtKB=A0A5F8GPE3 A0A5F8GPE3 KHK PTHR43085:SF55 HEXOKINASE FAMILY MEMBER KETOHEXOKINASE carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of polysaccharide metabolic process#GO:0032881;biological regulation#GO:0065007;regulation of glycogen biosynthetic process#GO:0005979;regulation of carbohydrate metabolic process#GO:0006109;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of cellular process#GO:0050794;small molecule metabolic process#GO:0044281;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065;transferase#PC00220 Fructose galactose metabolism#P02744>Ketohexokinase#P02963 MONDO|Ensembl=ENSMODG00000012389.4|UniProtKB=F6PNC2 F6PNC2 MAIP1 PTHR13333:SF5 M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;establishment of protein localization#GO:0045184;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000018287.4|UniProtKB=F6PWQ2 F6PWQ2 DYRK4 PTHR24058:SF136 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 4 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000019896.4|UniProtKB=F6W5T9 F6W5T9 PTHR24254:SF10 PROTHROMBIN PROTHROMBIN serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;blood coagulation#GO:0007596;platelet activation#GO:0030168;coagulation#GO:0050817;positive regulation of biological process#GO:0048518;regulation of hemostasis#GO:1900046;cellular process#GO:0009987;regulation of response to wounding#GO:1903034;response to wounding#GO:0009611;response to stress#GO:0006950;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of coagulation#GO:0050818;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;regulation of response to external stimulus#GO:0032101;cell activation#GO:0001775;positive regulation of coagulation#GO:0050820;regulation of biological quality#GO:0065008;wound healing#GO:0042060;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;hemostasis#GO:0007599;regulation of wound healing#GO:0061041;regulation of blood coagulation#GO:0030193;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 Blood coagulation#P00011>Prothrombin#P00416;Blood coagulation#P00011>Thrombin#P00414 MONDO|Ensembl=ENSMODG00000013200.3|UniProtKB=A0A5F8HCV3 A0A5F8HCV3 PTHR22761:SF12 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 5 cellular localization#GO:0051641;localization#GO:0051179;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;membrane assembly#GO:0071709;establishment of localization#GO:0051234;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;nuclear envelope organization#GO:0006998;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;nuclear membrane organization#GO:0071763;establishment of localization in cell#GO:0051649 organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;nucleus#GO:0005634;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000012903.5|UniProtKB=F7GKX9 F7GKX9 IP6K1 PTHR12400:SF73 INOSITOL POLYPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE KINASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;glycerophospholipid biosynthetic process#GO:0046474;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;organophosphate metabolic process#GO:0019637;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 kinase#PC00137 MONDO|Ensembl=ENSMODG00000014028.4|UniProtKB=A0A5F8GUE1 A0A5F8GUE1 LOC100029905 PTHR45690:SF15 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 14 regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;regulation of biological process#GO:0050789;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000003929.3|UniProtKB=F7GIX8 F7GIX8 GXYLT2 PTHR46012:SF1 IP22168P GLUCOSIDE XYLOSYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252;xylosyltransferase activity#GO:0042285;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;biosynthetic process#GO:0009058 MONDO|Ensembl=ENSMODG00000024918.2|UniProtKB=F6SFR4 F6SFR4 PTHR23050:SF350 CALCIUM BINDING PROTEIN CENTRIN-4 ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;organelle assembly#GO:0070925;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000020914.4|UniProtKB=H9H7S6 H9H7S6 SKI PTHR10005:SF15 SKI ONCOGENE-RELATED SKI ONCOGENE RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of BMP signaling pathway#GO:0030514;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of BMP signaling pathway#GO:0030510;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of signal transduction#GO:0009966;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 MONDO|Ensembl=ENSMODG00000018215.3|UniProtKB=K7E1Y8 K7E1Y8 FAM234B PTHR21419:SF25 FAMILY NOT NAMED PROTEIN FAM234B MONDO|Ensembl=ENSMODG00000019131.4|UniProtKB=F7EC85 F7EC85 ADAMTS3 PTHR13723:SF158 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 3 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000021025.4|UniProtKB=F6QYY9 F6QYY9 NDUFV3 PTHR17117:SF3 NADH-UBIQUINONE OXIDOREDUCTASE NADH:UBIQUINONE OXIDOREDUCTASE SUBUNIT V3 electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060 respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000008227.4|UniProtKB=F6ZY45 F6ZY45 PTHR22792:SF166 LUPUS LA PROTEIN-RELATED LUPUS LA PROTEIN HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000010583.3|UniProtKB=F7GHS9 F7GHS9 PTHR24232:SF54 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 35 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000047811.1|UniProtKB=A0A5F8GMX4 A0A5F8GMX4 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000017500.3|UniProtKB=F7F1B0 F7F1B0 PNPLA4 PTHR12406:SF48 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 4 carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;triacylglycerol lipase activity#GO:0004806;acyltransferase activity#GO:0016746;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 chemical homeostasis#GO:0048878;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;cellular process#GO:0009987;lipid catabolic process#GO:0016042;glycerolipid catabolic process#GO:0046503;triglyceride catabolic process#GO:0019433;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;homeostatic process#GO:0042592;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000024978.2|UniProtKB=F6UDY8 F6UDY8 PTHR11220:SF69 HEME-BINDING PROTEIN-RELATED HEME BINDING PROTEIN 2 binding#GO:0005488;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000025788.2|UniProtKB=F7FSP6 F7FSP6 AKTIP PTHR24067:SF294 UBIQUITIN-CONJUGATING ENZYME E2 PROTEIN CROSSBRONX-LIKE-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 response to stress#GO:0006950;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;DNA metabolic process#GO:0006259;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;ubiquitin ligase complex#GO:0000151;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000009216.3|UniProtKB=F7EED4 F7EED4 PTHR46330:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;cell communication#GO:0007154;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of apoptotic process#GO:0043065;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;apoptotic signaling pathway#GO:0097190 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 p53 pathway#P00059>KILLER/DR5#G01568;Apoptosis signaling pathway#P00006>TRAIL-R#P00276 MONDO|Ensembl=ENSMODG00000045078.1|UniProtKB=A0A5F8H5K9 A0A5F8H5K9 RAB20 PTHR24073:SF941 DRAB5-RELATED RAS-RELATED PROTEIN RAB-20 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;import into cell#GO:0098657;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;endocytosis#GO:0006897;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000011679.4|UniProtKB=A0A5F8H2Z6 A0A5F8H2Z6 ATP2A2 PTHR42861:SF18 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE-RELATED metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626 cellular homeostasis#GO:0019725;calcium-mediated signaling#GO:0019722;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;regulation of system process#GO:0044057;monoatomic ion transmembrane transport#GO:0034220;macroautophagy#GO:0016236;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;vacuole organization#GO:0007033;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;organelle assembly#GO:0070925;regulation of heart contraction#GO:0008016;homeostatic process#GO:0042592;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;autophagosome assembly#GO:0000045;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;cellular component organization or biogenesis#GO:0071840;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;intracellular signaling cassette#GO:0141124;regulation of multicellular organismal process#GO:0051239;monoatomic cation transmembrane transport#GO:0098655;cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;cellular process#GO:0009987;signal transduction#GO:0007165;autophagy#GO:0006914;monoatomic ion homeostasis#GO:0050801;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;process utilizing autophagic mechanism#GO:0061919;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;regulation of muscle contraction#GO:0006937;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;regulation of muscle system process#GO:0090257 membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000038943.1|UniProtKB=F6TC13 F6TC13 LOC100025780 PTHR12960:SF0 GLE-1-RELATED MRNA EXPORT FACTOR GLE1 small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;lipid binding#GO:0008289;protein binding#GO:0005515;phospholipid binding#GO:0005543;alcohol binding#GO:0043178;translation initiation factor binding#GO:0031369 nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;localization#GO:0051179;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;gene expression#GO:0010467 organelle envelope#GO:0031967;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translation factor#PC00223 MONDO|Ensembl=ENSMODG00000002469.3|UniProtKB=F7DDP4 F7DDP4 TM2D1 PTHR21016:SF1 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 1 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of Notch signaling pathway#GO:0045747;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;positive regulation of signal transduction#GO:0009967;apoptotic signaling pathway#GO:0097190;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000041145.1|UniProtKB=A0A5F8HCL8 A0A5F8HCL8 PTHR26453:SF17 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009192.3|UniProtKB=A0A5F8H421 A0A5F8H421 PTHR42707:SF2 ACYL-COA DEHYDROGENASE ACD11 DEHYDROGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000016614.4|UniProtKB=F6ZC79 F6ZC79 INTS13 PTHR12955:SF1 SARCOMA ANTIGEN NY-SAR-95-RELATED INTEGRATOR COMPLEX SUBUNIT 13 localization#GO:0051179;regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;biological regulation#GO:0065007;centrosome localization#GO:0051642;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;integrator complex#GO:0032039;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000046145.1|UniProtKB=A0A5F8H692 A0A5F8H692 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000010135.4|UniProtKB=F6WML5 F6WML5 HIRA PTHR13831:SF0 MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS PROTEIN HIRA protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000003567.3|UniProtKB=F7G112 F7G112 PNO1 PTHR12826:SF13 RIBONUCLEASE Y RNA-BINDING PROTEIN PNO1 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 endoribonuclease#PC00094 MONDO|Ensembl=ENSMODG00000042948.1|UniProtKB=A0A5F8G5B0 A0A5F8G5B0 PTHR24028:SF133 CADHERIN-87A PROTOCADHERIN ALPHA-9 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000014089.4|UniProtKB=F6R4F6 F6R4F6 BAK1 PTHR11256:SF41 BCL-2 RELATED BCL-2 HOMOLOGOUS ANTAGONIST_KILLER channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;response to stress#GO:0006950;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;release of cytochrome c from mitochondria#GO:0001836;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;apoptotic signaling pathway#GO:0097190;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;regulation of cellular process#GO:0050794;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 Apoptosis signaling pathway#P00006>Bak#P00275 MONDO|Ensembl=ENSMODG00000008037.4|UniProtKB=F6ZYP6 F6ZYP6 COX10 PTHR43448:SF2 PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;porphyrin-containing compound biosynthetic process#GO:0006779;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440;cellular process#GO:0009987;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220;acyltransferase#PC00042 Heme biosynthesis#P02746>Protoheme IX farnesyl transferase#P02982 MONDO|Ensembl=ENSMODG00000009404.2|UniProtKB=A0A5F8GUC3 A0A5F8GUC3 PTHR24347:SF254 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE H1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000015011.4|UniProtKB=A0A5F8G5Y9 A0A5F8G5Y9 EHMT2 PTHR46307:SF1 G9A, ISOFORM B HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000024787.2|UniProtKB=F7G0G3 F7G0G3 PHOSPHO2 PTHR20889:SF1 PHOSPHATASE, ORPHAN 1, 2 PYRIDOXAL PHOSPHATE PHOSPHATASE PHOSPHO2 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000013642.3|UniProtKB=F6UE26 F6UE26 TMEM179 PTHR31872:SF4 TRANSMEMBRANE PROTEIN 179 TRANSMEMBRANE PROTEIN 179 MONDO|Ensembl=ENSMODG00000051150.1|UniProtKB=A0A5F8HBL0 A0A5F8HBL0 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025108.3|UniProtKB=F6RP67 F6RP67 PTHR25466:SF2 T-LYMPHOCYTE ACTIVATION ANTIGEN T-LYMPHOCYTE ACTIVATION ANTIGEN CD86 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>B7#P01337 MONDO|Ensembl=ENSMODG00000012361.4|UniProtKB=F7DHQ2 F7DHQ2 DPY19L3 PTHR31488:SF4 DPY-19-LIKE 1, LIKE (H. SAPIENS) PROTEIN C-MANNOSYL-TRANSFERASE DPY19L3 glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000015535.4|UniProtKB=A0A5F8GIS8 A0A5F8GIS8 CLIP4 PTHR18916:SF32 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 4 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cytoplasmic microtubule organization#GO:0031122;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017 cell periphery#GO:0071944;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell cortex#GO:0005938;microtubule end#GO:1990752;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000013954.3|UniProtKB=F6RT53 F6RT53 PTHR47769:SF1 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 8 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 8 MONDO|Ensembl=ENSMODG00000028253.2|UniProtKB=A0A5F8G2I4 A0A5F8G2I4 PTHR16237:SF3 ODONTOGENIC AMELOBLAST-ASSOCIATED PROTEIN ODONTOGENIC AMELOBLAST-ASSOCIATED PROTEIN positive regulation of cell population proliferation#GO:0008284;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;response to stimulus#GO:0050896;odontogenesis#GO:0042476;positive regulation of epithelial cell proliferation#GO:0050679;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127;wound healing#GO:0042060;response to stress#GO:0006950;response to wounding#GO:0009611;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;odontogenesis of dentin-containing tooth#GO:0042475;biological regulation#GO:0065007;developmental process#GO:0032502;animal organ development#GO:0048513 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000003208.4|UniProtKB=K7E4I1 K7E4I1 HAUS1 PTHR31570:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1 centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;HAUS complex#GO:0070652;cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000001231.4|UniProtKB=F7G7D1 F7G7D1 PTHR11716:SF1 PHOSPHOLIPASE A2 FAMILY MEMBER OTOCONIN-90 phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;A2-type glycerophospholipase activity#GO:0004623;calcium ion binding#GO:0005509;binding#GO:0005488;lipid binding#GO:0008289;metal ion binding#GO:0046872;hydrolase activity, acting on ester bonds#GO:0016788;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;ion binding#GO:0043167;small molecule binding#GO:0036094;lipase activity#GO:0016298;cation binding#GO:0043169;hydrolase activity#GO:0016787 phosphatidylglycerol metabolic process#GO:0046471;phosphatidylcholine metabolic process#GO:0046470;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000011662.4|UniProtKB=F6YEE1 F6YEE1 ODR4 PTHR33966:SF1 PROTEIN ODR-4 HOMOLOG PROTEIN ODR-4 HOMOLOG macromolecule localization#GO:0033036;localization#GO:0051179;intracellular protein localization#GO:0008104 MONDO|Ensembl=ENSMODG00000042906.1|UniProtKB=F7D2A4 F7D2A4 LOC100618096 PTHR26453:SF607 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2AG2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016193.4|UniProtKB=F7FYA0 F7FYA0 TSR3 PTHR20426:SF0 RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG 18S RRNA AMINOCARBOXYPROPYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on RNA#GO:0140098 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000017951.4|UniProtKB=A0A5F8H336 A0A5F8H336 FIG4 PTHR45738:SF5 POLYPHOSPHOINOSITIDE PHOSPHATASE POLYPHOSPHOINOSITIDE PHOSPHATASE catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018 phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000024297.2|UniProtKB=F7EIE9 F7EIE9 LOC100024460 PTHR48018:SF112 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014151.4|UniProtKB=F6X307 F6X307 CATSPER4 PTHR47077:SF1 ION_TRANS DOMAIN-CONTAINING PROTEIN CATION CHANNEL SPERM-ASSOCIATED PROTEIN 4 calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832 developmental maturation#GO:0021700;male gamete generation#GO:0048232;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;transport#GO:0006810;cell maturation#GO:0048469;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;developmental process involved in reproduction#GO:0003006;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;cell motility#GO:0048870;microtubule-based movement#GO:0007018;metal ion transport#GO:0030001;reproductive process#GO:0022414;sexual reproduction#GO:0019953;spermatid development#GO:0007286;localization#GO:0051179;monoatomic cation transport#GO:0006812;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;sperm capacitation#GO:0048240;microtubule-based process#GO:0007017;sperm motility#GO:0097722;sodium ion transport#GO:0006814;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;monoatomic ion transport#GO:0006811 monoatomic ion channel complex#GO:0034702;endomembrane system#GO:0012505;sperm flagellum#GO:0036126;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;motile cilium#GO:0031514;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;transporter complex#GO:1990351;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;voltage-gated calcium channel complex#GO:0005891;intracellular vesicle#GO:0097708;sperm principal piece#GO:0097228;calcium channel complex#GO:0034704;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729 MONDO|Ensembl=ENSMODG00000001735.4|UniProtKB=F6X065 F6X065 MYC PTHR45851:SF1 MYC PROTO-ONCOGENE MYC PROTO-ONCOGENE PROTEIN RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 CCKR signaling map#P06959>MYC#G06979;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;PDGF signaling pathway#P00047>c-Myc#P01172;Oxidative stress response#P00046>Myc#P01124;p53 pathway feedback loops 2#P04398>Myc#P04649;CCKR signaling map#P06959>MYC#G07272;Interleukin signaling pathway#P00036>c-Myc#P00995 MONDO|Ensembl=ENSMODG00000004658.3|UniProtKB=F6UMV3 F6UMV3 DNTT PTHR11276:SF21 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA NUCLEOTIDYLEXOTRANSFERASE nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;DNA-directed DNA polymerase activity#GO:0003887 double-strand break repair#GO:0006302;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009;DNA-directed DNA polymerase#PC00018 MONDO|Ensembl=ENSMODG00000005529.3|UniProtKB=F7FHF8 F7FHF8 ARGLU1 PTHR31711:SF1 ARGININE AND GLUTAMATE-RICH PROTEIN 1 ARGININE AND GLUTAMATE-RICH PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000040118.1|UniProtKB=A0A5F8GVA1 A0A5F8GVA1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010008.2|UniProtKB=F6UAW7 F6UAW7 PTHR15426:SF6 PROTEIN DEPP1 PROTEIN DEPP1 regulation of autophagy#GO:0010506;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of catabolic process#GO:0009894 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000011530.4|UniProtKB=F6QXX7 F6QXX7 CALR PTHR11073:SF16 CALRETICULIN AND CALNEXIN CALRETICULIN metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein folding#GO:0006457 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000004421.3|UniProtKB=F6SD65 F6SD65 PTHR12277:SF52 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17A hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;palmitoyl hydrolase activity#GO:0098599;hydrolase activity#GO:0016787 regulation of synapse organization#GO:0050807;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;negative regulation of biological process#GO:0048519;regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007 vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;cytoplasm#GO:0005737;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000008920.2|UniProtKB=F7GL76 F7GL76 CHRNA7 PTHR18945:SF907 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-7 signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;monoatomic cation transmembrane transporter activity#GO:0008324;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276 trans-synaptic signaling#GO:0099537;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;transport#GO:0006810;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271 plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;presynaptic membrane#GO:0042734;membrane#GO:0016020;neuron projection#GO:0043005;presynapse#GO:0098793;cell periphery#GO:0071944;cell junction#GO:0030054;transporter complex#GO:1990351;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cell body#GO:0044297;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;axon#GO:0030424 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079 MONDO|Ensembl=ENSMODG00000041835.1|UniProtKB=A0A5F8G6Y8 A0A5F8G6Y8 PTHR23262:SF50 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-8 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000048040.1|UniProtKB=A0A5F8HJX5 A0A5F8HJX5 PTHR15902:SF2 NEURITIN-RELATED NEURITIN-LIKE PROTEIN cellular process#GO:0009987;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;growth#GO:0040007;plasma membrane bounded cell projection morphogenesis#GO:0120039;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;developmental growth#GO:0048589;cell growth#GO:0016049;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;developmental cell growth#GO:0048588;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron projection extension#GO:1990138;developmental growth involved in morphogenesis#GO:0060560;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000009360.3|UniProtKB=F7G026 F7G026 MRPL15 PTHR12934:SF15 50S RIBOSOMAL PROTEIN L15 LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000007422.4|UniProtKB=F7EE54 F7EE54 RNF2 PTHR46076:SF4 E3 UBIQUITIN-PROTEIN LIGASE RING1 / RING 2 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RING2 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;chromatin binding#GO:0003682;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;PcG protein complex#GO:0031519;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000017017.4|UniProtKB=F6QEW4 F6QEW4 RIOX2 PTHR13096:SF7 MINA53 MYC INDUCED NUCLEAR ANTIGEN RIBOSOMAL OXYGENASE 2 MONDO|Ensembl=ENSMODG00000010381.4|UniProtKB=F7AVA0 F7AVA0 PTHR14239:SF5 DUDULIN-RELATED METALLOREDUCTASE STEAP4 oxidoreductase activity, acting on metal ions#GO:0016722;oxidoreductase activity#GO:0016491;ferric-chelate reductase activity#GO:0000293;catalytic activity#GO:0003824 monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;transition metal ion transport#GO:0000041;transport#GO:0006810 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 reductase#PC00198 MONDO|Ensembl=ENSMODG00000013320.4|UniProtKB=A0A5F8GS13 A0A5F8GS13 ZNF839 PTHR16116:SF5 ZINC FINGER PROTEIN 839 ZINC FINGER PROTEIN 839 MONDO|Ensembl=ENSMODG00000014906.4|UniProtKB=A0A5F8GB76 A0A5F8GB76 TENM1 PTHR11219:SF7 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular process#GO:0009987;cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell adhesion#GO:0007155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;synaptic membrane adhesion#GO:0099560;axon development#GO:0061564;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;cell junction organization#GO:0034330;synapse organization#GO:0050808;system development#GO:0048731;anatomical structure development#GO:0048856 cell junction#GO:0030054;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202 MONDO|Ensembl=ENSMODG00000016811.5|UniProtKB=A0A5F8G2V8 A0A5F8G2V8 ROBO2 PTHR12231:SF242 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN ROUNDABOUT HOMOLOG 2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;cell recognition#GO:0008037;animal gross anatomical part developmental process#GO:0160108 cell projection membrane#GO:0031253;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;main axon#GO:0044304;membrane#GO:0016020;cell leading edge#GO:0031252 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 Axon guidance mediated by Slit/Robo#P00008>Robo#P00348 MONDO|Ensembl=ENSMODG00000036470.1|UniProtKB=A0A5F8H7Z9 A0A5F8H7Z9 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000014712.3|UniProtKB=F7D310 F7D310 RNF43 PTHR16200:SF2 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE RNF43 transferase activity#GO:0016740;catalytic activity#GO:0003824;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;signaling receptor binding#GO:0005102;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;protein metabolic process#GO:0019538;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;negative regulation of signaling#GO:0023057 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000050628.1|UniProtKB=A0A5F8GR41 A0A5F8GR41 WDR55 PTHR44019:SF20 WD REPEAT-CONTAINING PROTEIN 55 WD REPEAT-CONTAINING PROTEIN 55 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000014922.4|UniProtKB=F7FVR7 F7FVR7 CALR3 PTHR11073:SF3 CALRETICULIN AND CALNEXIN CALRETICULIN-3 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;protein folding#GO:0006457;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;response to chemical#GO:0042221;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950 membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000050644.1|UniProtKB=A0A5F8G9P5 A0A5F8G9P5 CXXC4 PTHR13419:SF1 ZINC FINGER-CONTAINING CXXC-TYPE ZINC FINGER PROTEIN 4 nucleic acid binding#GO:0003676;binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;sequence-specific DNA binding#GO:0043565;nucleotide binding#GO:0000166 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000020060.3|UniProtKB=F6YSN8 F6YSN8 LOC100024539 PTHR48018:SF105 OLFACTORY RECEPTOR OLFACTORY RECEPTOR OR9H1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040739.1|UniProtKB=A0A5F8HLE2 A0A5F8HLE2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000018084.4|UniProtKB=F7FTI1 F7FTI1 NECTIN3 PTHR23277:SF12 NECTIN-RELATED NECTIN-3 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;protein binding#GO:0005515 heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912;apical junction complex#GO:0043296 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000007111.4|UniProtKB=F6SI50 F6SI50 HEXD PTHR21040:SF6 BCDNA.GH04120 HEXOSAMINIDASE D hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 MONDO|Ensembl=ENSMODG00000003886.4|UniProtKB=F7DT46 F7DT46 METTL13 PTHR12176:SF78 SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN EEF1A LYSINE AND N-TERMINAL METHYLTRANSFERASE protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000014387.4|UniProtKB=F6T7R4 F6T7R4 COG4 PTHR24016:SF21 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4 transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;Golgi organization#GO:0007030;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;organelle organization#GO:0006996;retrograde transport, vesicle recycling within Golgi#GO:0000301;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;COG complex#GO:0017119 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000006834.4|UniProtKB=F6PG36 F6PG36 PTHR11860:SF101 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CD300 MOLECULE LIKE FAMILY MEMBER D2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 immune response-activating signaling pathway#GO:0002757;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cell communication#GO:0007154;immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000046257.1|UniProtKB=A0A5F8HBG5 A0A5F8HBG5 PTHR11375:SF5 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER E histone binding#GO:0042393;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208;binding#GO:0005488;molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of programmed cell death#GO:0043067 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000004864.4|UniProtKB=F6TNW7 F6TNW7 KIF4A PTHR47969:SF15 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;isomerase activity#GO:0016853 organelle organization#GO:0006996;cellular process#GO:0009987;spindle elongation#GO:0051231;cytoskeleton organization#GO:0007010;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;nuclear chromosome segregation#GO:0098813;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;microtubule cytoskeleton organization#GO:0000226 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 microtubule binding motor protein#PC00156;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000003856.4|UniProtKB=F7DU14 F7DU14 DSCC1 PTHR13395:SF6 SISTER CHROMATID COHESION PROTEIN DCC1-RELATED SISTER CHROMATID COHESION PROTEIN DCC1 chromosome organization#GO:0051276;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;mitotic sister chromatid cohesion#GO:0007064 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 replication origin binding protein#PC00199;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000043691.1|UniProtKB=A0A5F8HC08 A0A5F8HC08 SZRD1 PTHR31796:SF2 SUZ DOMAIN-CONTAINING PROTEIN 1 SUZ RNA-BINDING DOMAIN-CONTAINING MONDO|Ensembl=ENSMODG00000016736.3|UniProtKB=F7BYS0 F7BYS0 PTHR11736:SF14 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN NSE3 HOMOLOG, SMC5-SMC6 COMPLEX COMPONENT nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000024386.2|UniProtKB=F6UPK1 F6UPK1 PTHR48002:SF76 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C11 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012463.3|UniProtKB=A0A5F8GZ13 A0A5F8GZ13 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000009926.4|UniProtKB=F6R8Z7 F6R8Z7 PLEK2 PTHR12092:SF2 PLECKSTRIN PLECKSTRIN-2 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000005034.3|UniProtKB=F7E999 F7E999 CLDN15 PTHR13247:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11 MITOCHONDRIAL FISSION 1 PROTEIN lipid binding#GO:0008289;binding#GO:0005488 organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840;peroxisome organization#GO:0007031;mitochondrial fission#GO:0000266;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial envelope#GO:0005740;microbody#GO:0042579;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;peroxisomal membrane#GO:0005778;organelle outer membrane#GO:0031968;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;peroxisome#GO:0005777;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000020715.3|UniProtKB=A0A5F8H2S0 A0A5F8H2S0 METAP1 PTHR43330:SF7 METHIONINE AMINOPEPTIDASE METHIONINE AMINOPEPTIDASE 1 peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000050912.1|UniProtKB=F7DY80 F7DY80 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000021496.4|UniProtKB=F7G2S4 F7G2S4 RIOK3 PTHR45723:SF1 SERINE/THREONINE-PROTEIN KINASE RIO1 SERINE_THREONINE-PROTEIN KINASE RIO3 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000015066.4|UniProtKB=A0A5F8GAF8 A0A5F8GAF8 PNPLA6 PTHR14226:SF26 NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 6 phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;lipase activity#GO:0016298 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 esterase#PC00097;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000010653.4|UniProtKB=F7D459 F7D459 ITGAV PTHR23220:SF4 INTEGRIN ALPHA INTEGRIN ALPHA-V signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;multicellular organismal process#GO:0032501;tube development#GO:0035295;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;signal transduction#GO:0007165;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;response to stimulus#GO:0050896;signaling#GO:0023052;blood vessel morphogenesis#GO:0048514;integrin-mediated signaling pathway#GO:0007229;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;membrane protein complex#GO:0098796;membrane#GO:0016020;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 integrin#PC00126;cell adhesion molecule#PC00069 CCKR signaling map#P06959>ITGAV#G07293;CCKR signaling map#P06959>ITGAV#G06999;CCKR signaling map#P06959>ITGAV#P07133;Integrin signalling pathway#P00034>Integrin alpha#P00941 MONDO|Ensembl=ENSMODG00000020745.5|UniProtKB=F7G971 F7G971 AFF1 PTHR10528:SF6 AF4/FMR2 FAMILY MEMBER AF4_FMR2 FAMILY MEMBER 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;RNA metabolic process#GO:0016070;nervous system process#GO:0050877;nucleic acid biosynthetic process#GO:0141187;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;DNA-templated transcription elongation#GO:0006354;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;system process#GO:0003008;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000017425.4|UniProtKB=F6ZVD4 F6ZVD4 CLCN4 PTHR45711:SF2 CHLORIDE CHANNEL PROTEIN H(+)_CL(-) EXCHANGE TRANSPORTER 4 monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820 membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000000983.4|UniProtKB=F7ES42 F7ES42 EPHB6 PTHR46877:SF15 EPH RECEPTOR A5 EPHRIN TYPE-B RECEPTOR 6 phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;axon development#GO:0061564;axon guidance#GO:0007411;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 dendritic tree#GO:0097447;dendrite#GO:0030425;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000022957.2|UniProtKB=F6RH69 F6RH69 TAL2 PTHR13864:SF21 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000048839.1|UniProtKB=F6Z9G8 F6Z9G8 VN2R528 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005283.4|UniProtKB=F7E6U7 F7E6U7 ANGPT1 PTHR19143:SF156 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-1 protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;binding#GO:0005488;signaling receptor binding#GO:0005102;receptor tyrosine kinase binding#GO:0030971 blood vessel morphogenesis#GO:0048514;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;system development#GO:0048731;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;tube development#GO:0035295;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Angiogenesis#P00005>Ang-1#P00248 MONDO|Ensembl=ENSMODG00000018167.4|UniProtKB=F7CCG9 F7CCG9 C1S PTHR24255:SF18 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED COMPLEMENT C1S SUBCOMPONENT serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000010326.4|UniProtKB=F6S9J6 F6S9J6 GPAM PTHR12563:SF16 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1, MITOCHONDRIAL acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 neutral lipid metabolic process#GO:0006638;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;triglyceride biosynthetic process#GO:0019432;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000002765.3|UniProtKB=F6YW13 F6YW13 PTHR11361:SF156 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH2 ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;catalytic activity, acting on DNA#GO:0140097 mitotic recombination#GO:0006312;system development#GO:0048731;anatomical structure development#GO:0048856;somatic diversification of immune receptors#GO:0002200;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;developmental process#GO:0032502;DNA damage response#GO:0006974;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;adaptive immune response#GO:0002250;somatic cell DNA recombination#GO:0016444;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501;cellular response to stress#GO:0033554;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;immune system development#GO:0002520;lymphocyte mediated immunity#GO:0002449;mismatch repair#GO:0006298;production of molecular mediator of immune response#GO:0002440;response to stimulus#GO:0050896;immune effector process#GO:0002252;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;multicellular organism development#GO:0007275;somatic recombination of immunoglobulin gene segments#GO:0016447;cellular process#GO:0009987;response to stress#GO:0006950;gene expression#GO:0010467 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000042093.1|UniProtKB=A0A5F8GV92 A0A5F8GV92 LOC100016938 PTHR26450:SF422 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048877.1|UniProtKB=A0A5F8H975 A0A5F8H975 PITX1 PTHR45882:SF1 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX 1 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>PITX#P06722 MONDO|Ensembl=ENSMODG00000017230.4|UniProtKB=A0A5F8HD59 A0A5F8HD59 PTHR34479:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 30 COILED-COIL DOMAIN-CONTAINING PROTEIN 30 MONDO|Ensembl=ENSMODG00000016300.5|UniProtKB=A0A5F8GKY0 A0A5F8GKY0 ARHGAP17 PTHR14130:SF3 3BP-1 RELATED RHOGAP RHO GTPASE-ACTIVATING PROTEIN 17 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of actin cytoskeleton organization#GO:0032956 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000045345.1|UniProtKB=A0A5F8HCP0 A0A5F8HCP0 SLC26A2 PTHR11814:SF16 SULFATE TRANSPORTER SULFATE TRANSPORTER secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075;carboxylic acid transmembrane transporter activity#GO:0046943 monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;chloride transmembrane transport#GO:1902476;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;chloride transport#GO:0006821 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000016547.4|UniProtKB=A0A5F8H621 A0A5F8H621 TEF PTHR11988:SF24 THYROTROPH EMBRYONIC FACTOR RELATED THYROTROPH EMBRYONIC FACTOR RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;basic leucine zipper transcription factor#PC00056 MONDO|Ensembl=ENSMODG00000015420.4|UniProtKB=F6T3D4 F6T3D4 LOC100017234 PTHR19229:SF98 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA3 ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 lipid localization#GO:0010876;macromolecule localization#GO:0033036;transport#GO:0006810;localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000002479.4|UniProtKB=A0A5F8GIC9 A0A5F8GIC9 MRPS9 PTHR21569:SF47 RIBOSOMAL PROTEIN S9 SMALL RIBOSOMAL SUBUNIT PROTEIN US9M structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000012627.4|UniProtKB=F6WUE3 F6WUE3 CWC25 PTHR16196:SF0 CELL CYCLE CONTROL PROTEIN CWF25 PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000022934.2|UniProtKB=F6PZ60 F6PZ60 LOC100020532 PTHR26450:SF392 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000037603.1|UniProtKB=A0A5F8HHJ4 A0A5F8HHJ4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016052.4|UniProtKB=A0A5F8GMK0 A0A5F8GMK0 NRP2 PTHR46806:SF2 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN NEUROPILIN-2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 anatomical structure development#GO:0048856;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection development#GO:0031175;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944;neuron projection#GO:0043005;cell junction#GO:0030054;postsynaptic membrane#GO:0045211;synaptic membrane#GO:0097060;axon#GO:0030424 MONDO|Ensembl=ENSMODG00000037696.1|UniProtKB=A0A5F8G528 A0A5F8G528 PTHR12606:SF11 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 2 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protease#PC00190 MONDO|Ensembl=ENSMODG00000028122.2|UniProtKB=K7E218 K7E218 LOC100020928 PTHR12015:SF103 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 4-LIKE cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cell surface receptor signaling pathway#GO:0007166;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;taxis#GO:0042330;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;response to peptide#GO:1901652;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of cell motility#GO:2000147;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;regulation of cell migration#GO:0030334;leukocyte migration#GO:0050900;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;positive regulation of locomotion#GO:0040017;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;positive regulation of cell migration#GO:0030335;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;cell migration#GO:0016477;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cytokine-mediated signaling pathway#GO:0019221;cell chemotaxis#GO:0060326;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;regulation of cell motility#GO:2000145;chemokine-mediated signaling pathway#GO:0070098;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;cellular response to chemokine#GO:1990869;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cell motility#GO:0048870 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000020226.4|UniProtKB=A0A5F8G4M2 A0A5F8G4M2 TMEM161B PTHR13624:SF3 RE42071P TRANSMEMBRANE PROTEIN 161B MONDO|Ensembl=ENSMODG00000001190.5|UniProtKB=A0A5F8GNG7 A0A5F8GNG7 STON1 PTHR12694:SF9 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 TFIIA-ALPHA AND BETA-LIKE FACTOR transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;core promoter sequence-specific DNA binding#GO:0001046;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription coregulator activity#GO:0003712 DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390;General transcription regulation#P00023>TFIIA complex#P00662 MONDO|Ensembl=ENSMODG00000016282.4|UniProtKB=F7AUL4 F7AUL4 GRID2IP PTHR45725:SF3 FORMIN HOMOLOGY 2 FAMILY MEMBER DELPHILIN MONDO|Ensembl=ENSMODG00000002869.4|UniProtKB=F7E297 F7E297 ENTREP1 PTHR17615:SF8 PROTEIN FAM189A ENDOSOMAL TRANSMEMBRANE EPSIN INTERACTOR 1 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 response to cytokine#GO:0034097;response to chemical#GO:0042221;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;receptor internalization#GO:0031623;response to chemokine#GO:1990868;signal transduction#GO:0007165;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;signaling#GO:0023052;cellular response to chemokine#GO:1990869;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;chemokine-mediated signaling pathway#GO:0070098;localization#GO:0051179;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;plasma membrane#GO:0005886;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;early endosome membrane#GO:0031901;late endosome membrane#GO:0031902;recycling endosome#GO:0055037;recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000013465.4|UniProtKB=F7FYK0 F7FYK0 HERPUD1 PTHR12943:SF7 HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UBIQUITIN-LIKE DOMAIN MEMBER 1 PROTEIN binding#GO:0005488;transmembrane transporter binding#GO:0044325;protein binding#GO:0005515 metabolic process#GO:0008152;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;chemical homeostasis#GO:0048878;regulation of apoptotic process#GO:0042981;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;regulation of intracellular signal transduction#GO:1902531;inorganic ion homeostasis#GO:0098771;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;negative regulation of intracellular signal transduction#GO:1902532;response to unfolded protein#GO:0006986;regulation of cellular response to stress#GO:0080135;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;regulation of response to stress#GO:0080134;intracellular monoatomic cation homeostasis#GO:0030003;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular chemical homeostasis#GO:0055082;endoplasmic reticulum unfolded protein response#GO:0030968;negative regulation of apoptotic process#GO:0043066;regulation of signal transduction#GO:0009966;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;protein metabolic process#GO:0019538;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of protein catabolic process#GO:0042176;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of intrinsic apoptotic signaling pathway#GO:2001242;catabolic process#GO:0009056;homeostatic process#GO:0042592;macromolecule catabolic process#GO:0009057;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;regulation of proteasomal protein catabolic process#GO:0061136;negative regulation of signal transduction#GO:0009968;calcium ion homeostasis#GO:0055074;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;negative regulation of cell communication#GO:0010648;intracellular monoatomic ion homeostasis#GO:0006873;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;monoatomic cation homeostasis#GO:0055080;macromolecule metabolic process#GO:0043170;cellular homeostasis#GO:0019725;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of apoptotic signaling pathway#GO:2001233;cellular response to topologically incorrect protein#GO:0035967;negative regulation of apoptotic signaling pathway#GO:2001234;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of ERAD pathway#GO:1904292 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 MONDO|Ensembl=ENSMODG00000014029.5|UniProtKB=F6V8L0 F6V8L0 ZIC3 PTHR19818:SF25 ZINC FINGER PROTEIN ZIC AND GLI ZIC FAMILY MEMBER 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000037063.1|UniProtKB=A0A5F8H285 A0A5F8H285 COX7C PTHR13313:SF0 CYTOCHROME C OXIDASE SUBUNIT VIIC CYTOCHROME C OXIDASE SUBUNIT 7C, MITOCHONDRIAL electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;transporter complex#GO:1990351;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803 oxidoreductase#PC00176;oxidase#PC00175 MONDO|Ensembl=ENSMODG00000001062.4|UniProtKB=A0A5F8GEB7 A0A5F8GEB7 FBXW7 PTHR19849:SF1 PHOSPHOLIPASE A-2-ACTIVATING PROTEIN F-BOX_WD REPEAT-CONTAINING PROTEIN 7 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 macroautophagy#GO:0016236;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;autophagy#GO:0006914;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;process utilizing autophagic mechanism#GO:0061919;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 Notch signaling pathway#P00045>Sel 10#P01102;Parkinson disease#P00049>hSel10#P01240 MONDO|Ensembl=ENSMODG00000012321.4|UniProtKB=F6QGR2 F6QGR2 PTHR48012:SF1 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE OSR1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cellular response to chemical stress#GO:0062197;cellular response to abiotic stimulus#GO:0071214;positive regulation of response to external stimulus#GO:0032103;response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;positive regulation of locomotion#GO:0040017;response to osmotic stress#GO:0006970;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;cell communication#GO:0007154;regulation of cell motility#GO:2000145;positive regulation of chemotaxis#GO:0050921;intracellular signal transduction#GO:0035556;regulation of lymphocyte migration#GO:2000401;cellular response to osmotic stress#GO:0071470;regulation of leukocyte migration#GO:0002685;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to environmental stimulus#GO:0104004;hyperosmotic response#GO:0006972;cellular response to stimulus#GO:0051716 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000029083.2|UniProtKB=K7E151 K7E151 LOC100016419 PTHR24064:SF460 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000001146.4|UniProtKB=F7D4D9 F7D4D9 TMEM254 PTHR34104:SF3 TRANSMEMBRANE PROTEIN 254 TRANSMEMBRANE PROTEIN 254 MONDO|Ensembl=ENSMODG00000009069.4|UniProtKB=F7FR03 F7FR03 NUDT1 PTHR43758:SF2 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE OXIDIZED PURINE NUCLEOSIDE TRIPHOSPHATE HYDROLASE hydrolase activity#GO:0016787;nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000050542.1|UniProtKB=A0A5F8GXQ7 A0A5F8GXQ7 PTHR24024:SF15 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A PULMONARY SURFACTANT-ASSOCIATED PROTEIN D molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023 regulation of endocytosis#GO:0030100;immune effector process#GO:0002252;humoral immune response#GO:0006959;regulation of transport#GO:0051049;regulation of localization#GO:0032879;activation of immune response#GO:0002253;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;defense response to other organism#GO:0098542;positive regulation of cellular component organization#GO:0051130;immune system process#GO:0002376;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;complement activation#GO:0006956;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;positive regulation of endocytosis#GO:0045807;regulation of immune response#GO:0050776;response to external biotic stimulus#GO:0043207;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 surfactant#PC00212;structural protein#PC00211 MONDO|Ensembl=ENSMODG00000019169.4|UniProtKB=A0A5F8GV99 A0A5F8GV99 PTHR11475:SF135 OXIDASE/PEROXIDASE LACTOPEROXIDASE antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;defense response#GO:0006952 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 MONDO|Ensembl=ENSMODG00000028889.2|UniProtKB=K7E1C3 K7E1C3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007653.3|UniProtKB=F7FZE7 F7FZE7 ARHGEF17 PTHR12877:SF15 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 17 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000016624.4|UniProtKB=F6YNB3 F6YNB3 MPG PTHR10429:SF0 DNA-3-METHYLADENINE GLYCOSYLASE DNA-3-METHYLADENINE GLYCOSYLASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;base-excision repair#GO:0006284;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 DNA metabolism protein#PC00009;DNA glycosylase#PC00010 MONDO|Ensembl=ENSMODG00000008318.4|UniProtKB=F7FGD2 F7FGD2 PRKD3 PTHR22968:SF26 PROTEIN KINASE C, MU SERINE_THREONINE-PROTEIN KINASE D3 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 EGF receptor signaling pathway#P00018>PKC#P00565;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219 MONDO|Ensembl=ENSMODG00000037686.1|UniProtKB=A0A5F8GY97 A0A5F8GY97 VN2R558 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000002406.4|UniProtKB=F6Z8F9 F6Z8F9 FAM3D PTHR14592:SF9 UNCHARACTERIZED FAM3 PROTEIN FAM3D molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000043683.1|UniProtKB=A0A5F8GX11 A0A5F8GX11 LOC100021946 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020263.4|UniProtKB=F7CJH3 F7CJH3 RASGRF2 PTHR23113:SF187 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR 2 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000044659.1|UniProtKB=A0A5F8GSC3 A0A5F8GSC3 LOC100616792 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000050095.1|UniProtKB=A0A5F8HA03 A0A5F8HA03 PFN3 PTHR13936:SF2 PROFILIN PROFILIN-3 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin filament polymerization#GO:0030833;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of actin filament bundle assembly#GO:0032233;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of actin filament bundle assembly#GO:0032231;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Profilin#P00521 MONDO|Ensembl=ENSMODG00000006132.2|UniProtKB=F7E1P0 F7E1P0 TMLHE PTHR10696:SF51 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED TRIMETHYLLYSINE DIOXYGENASE, MITOCHONDRIAL 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;carnitine metabolic process#GO:0009437;cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 metabolite interconversion enzyme#PC00262;hydroxylase#PC00122 MONDO|Ensembl=ENSMODG00000018279.4|UniProtKB=F6Q6H4 F6Q6H4 GABRR1 PTHR18945:SF30 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT RHO-1 transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;monoatomic anion channel activity#GO:0005253;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;chloride channel activity#GO:0005254;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888 chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;synaptic signaling#GO:0099536;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234 cell junction#GO:0030054;signaling receptor complex#GO:0043235;GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000003915.4|UniProtKB=F7G925 F7G925 CUL4A PTHR11932:SF68 CULLIN CULLIN-4A ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899;protein complex scaffold activity#GO:0140378;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;structural molecule activity#GO:0005198 protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein modification process#GO:0036211;ribonucleoprotein complex biogenesis#GO:0022613;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;ribosome biogenesis#GO:0042254;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;DNA damage response#GO:0006974;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000047760.1|UniProtKB=A0A5F8GM87 A0A5F8GM87 LOC100031215 PTHR26454:SF77 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025712.3|UniProtKB=A0A5F8H3H6 A0A5F8H3H6 DIS3L2 PTHR23355:SF68 RIBONUCLEASE DIS3-LIKE EXONUCLEASE 2 3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098 macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 exoribonuclease#PC00099 MONDO|Ensembl=ENSMODG00000008276.4|UniProtKB=F6Z7P3 F6Z7P3 LMTK2 PTHR24417:SF8 SERINE/THREONINE-PROTEIN KINASE LMTK1 SERINE_THREONINE-PROTEIN KINASE LMTK2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000011119.4|UniProtKB=A0A5F8G2M8 A0A5F8G2M8 ARHGAP39 PTHR45876:SF1 FI04035P RHO GTPASE-ACTIVATING PROTEIN 39 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000025205.1|UniProtKB=F7BFS8 F7BFS8 LOC100012775 PTHR19980:SF0 RNA CLEAVAGE STIMULATION FACTOR CLEAVAGE STIMULATION FACTOR SUBUNIT 3 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;nucleus#GO:0005634 mRNA polyadenylation factor#PC00146;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000023056.3|UniProtKB=A0A5F8H6E0 A0A5F8H6E0 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000002379.4|UniProtKB=F7G300 F7G300 SERPINA10 PTHR11461:SF191 SERINE PROTEASE INHIBITOR, SERPIN PROTEIN Z-DEPENDENT PROTEASE INHIBITOR endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>ZPI#P00425 MONDO|Ensembl=ENSMODG00000020690.4|UniProtKB=A0A5F8HJE3 A0A5F8HJE3 DAPP1 PTHR14336:SF15 TANDEM PH DOMAIN CONTAINING PROTEIN DUAL ADAPTER FOR PHOSPHOTYROSINE AND 3-PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDE phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488;small molecule binding#GO:0036094 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000012312.4|UniProtKB=A0A5F8GBM8 A0A5F8GBM8 RBM6 PTHR13948:SF22 RNA-BINDING PROTEIN RNA-BINDING PROTEIN 6 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000000696.4|UniProtKB=F6WLU0 F6WLU0 ATCAY PTHR12112:SF9 BNIP - RELATED CAYTAXIN cell death#GO:0008219;cellular process#GO:0009987;apoptotic process#GO:0006915;programmed cell death#GO:0012501 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000020092.4|UniProtKB=F7ESQ0 F7ESQ0 SPATA9 PTHR35669:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 9 SPERMATOGENESIS-ASSOCIATED PROTEIN 9 MONDO|Ensembl=ENSMODG00000029594.2|UniProtKB=K7DYV5 K7DYV5 PTHR23266:SF399 IMMUNOGLOBULIN HEAVY CHAIN NON-FUNCTIONAL IMMUNOGLOBULIN HEAVY VARIABLE 8-51-1-RELATED binding#GO:0005488;antigen binding#GO:0003823 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000049378.1|UniProtKB=A0A5F8G1U7 A0A5F8G1U7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000007274.2|UniProtKB=F7FQL6 F7FQL6 LOC100617146 PTHR24242:SF197 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000010391.4|UniProtKB=A0A5F8G9S3 A0A5F8G9S3 PTHR12305:SF99 PHOSPHATASE WITH HOMOLOGY TO TENSIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE TPTE2-RELATED phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Hypoxia response via HIF activation#P00030>PTEN#P00824;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#G04675;p53 pathway#P00059>PTEN#P01480;p53 pathway feedback loops 2#P04398>PTEN#P04658;p53 pathway#P00059>PTEN#G01579;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#P00905;p53 pathway feedback loops 2#P04398>PTEN#G04714 MONDO|Ensembl=ENSMODG00000004827.4|UniProtKB=F6ULX9 F6ULX9 ATP2C2 PTHR42861:SF23 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE TYPE 2C MEMBER 2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;calcium ion homeostasis#GO:0055074 cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000017111.3|UniProtKB=A0A5F8GQT5 A0A5F8GQT5 EFNA1 PTHR11304:SF19 EPHRIN EPHRIN-A1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;system development#GO:0048731;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;regulation of cellular process#GO:0050794;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000048529.1|UniProtKB=A0A5F8HLB4 A0A5F8HLB4 PTHR15359:SF5 IG-LIKE DOMAIN-CONTAINING PROTEIN PURKINJE CELL PROTEIN 4-LIKE PROTEIN 1 MONDO|Ensembl=ENSMODG00000001013.4|UniProtKB=F6ZFI7 F6ZFI7 PTHR11232:SF76 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER CARBOXYL-TERMINAL PDZ LIGAND OF NEURONAL NITRIC OXIDE SYNTHASE PROTEIN signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010203.4|UniProtKB=F6SAZ8 F6SAZ8 PTHR28567:SF1 PROTEIN FAM53A-LIKE ISOFORM X1 PROTEIN FAM53B intracellular protein localization#GO:0008104;positive regulation of canonical Wnt signaling pathway#GO:0090263;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;transport#GO:0006810;regulation of response to stimulus#GO:0048583;intracellular transport#GO:0046907;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;nuclear transport#GO:0051169;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;positive regulation of cell communication#GO:0010647;positive regulation of signal transduction#GO:0009967;intracellular protein transport#GO:0006886;positive regulation of Wnt signaling pathway#GO:0030177;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;establishment of protein localization#GO:0045184;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;protein import into nucleus#GO:0006606;protein transport#GO:0015031;cellular localization#GO:0051641;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of Wnt signaling pathway#GO:0030111;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000005677.3|UniProtKB=F6V4B8 F6V4B8 PCGF3 PTHR45893:SF5 POLYCOMB GROUP RING FINGER PROTEIN POLYCOMB GROUP RING FINGER PROTEIN 3 heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;PcG protein complex#GO:0031519;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000025768.3|UniProtKB=A0A5F8GDY4 A0A5F8GDY4 CIMIP6 PTHR35087:SF1 SIMILAR TO HYPOTHETICAL PROTEIN FLJ40298 CILIARY MICROTUBULE INNER PROTEIN 6 MONDO|Ensembl=ENSMODG00000017651.4|UniProtKB=K7E3I4 K7E3I4 LAMA2 PTHR10574:SF291 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-2 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;neuron projection development#GO:0031175;axon guidance#GO:0007411;axon development#GO:0061564;cellular process#GO:0009987;multicellular organismal process#GO:0032501;tissue development#GO:0009888;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008 extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 MONDO|Ensembl=ENSMODG00000049280.1|UniProtKB=A0A5F8G5V0 A0A5F8G5V0 UBALD1 PTHR31993:SF5 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 UBA-LIKE DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000006187.2|UniProtKB=F7AI30 F7AI30 FAM163A PTHR31914:SF2 PROTEIN FAM163A PROTEIN FAM163A MONDO|Ensembl=ENSMODG00000045047.1|UniProtKB=K7E4N4 K7E4N4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000018692.3|UniProtKB=F7FQQ2 F7FQQ2 LOC103094249 PTHR11905:SF148 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 30 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 reproductive structure development#GO:0048608;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;system development#GO:0048731;reproductive system development#GO:0061458;proteolysis#GO:0006508;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;gonad development#GO:0008406;male gonad development#GO:0008584;cellular process#GO:0009987;sex differentiation#GO:0007548;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;animal organ development#GO:0048513;development of primary male sexual characteristics#GO:0046546;metabolic process#GO:0008152;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;male sex differentiation#GO:0046661 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000000092.4|UniProtKB=F6YC68 F6YC68 TYRO3 PTHR24416:SF279 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR TYRO3 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;platelet aggregation#GO:0070527;import into cell#GO:0098657;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;coagulation#GO:0050817;response to stress#GO:0006950;cell-cell adhesion#GO:0098609;nervous system development#GO:0007399;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;wound healing#GO:0042060;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of body fluid levels#GO:0050878;endocytosis#GO:0006897;response to stimulus#GO:0050896;transport#GO:0006810;developmental process#GO:0032502;phagocytosis#GO:0006909;blood coagulation#GO:0007596;establishment of localization#GO:0051234;platelet activation#GO:0030168;response to wounding#GO:0009611;homotypic cell-cell adhesion#GO:0034109;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell migration#GO:0016477;cell activation#GO:0001775;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;localization#GO:0051179;cellular response to stimulus#GO:0051716;hemostasis#GO:0007599;regulation of cellular process#GO:0050794;cell motility#GO:0048870 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019528.4|UniProtKB=F6UV56 F6UV56 SCRT2 PTHR24388:SF48 ZINC FINGER PROTEIN TRANSCRIPTIONAL REPRESSOR SCRATCH 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000024530.2|UniProtKB=F6ZVX5 F6ZVX5 C1QBP PTHR10826:SF1 COMPLEMENT COMPONENT 1 COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN, MITOCHONDRIAL molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-RNA adaptor activity#GO:0140517 RNA catabolic process#GO:0006401;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 complement component#PC00078;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000001946.3|UniProtKB=H9H9D5 H9H9D5 RPS26 PTHR12538:SF0 40S RIBOSOMAL PROTEIN S26 40S RIBOSOMAL PROTEIN S26 binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000010221.4|UniProtKB=F6WM01 F6WM01 SEPTIN6 PTHR18884:SF55 SEPTIN SEPTIN-6 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 macromolecule localization#GO:0033036;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;cell division#GO:0051301;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;intracellular protein localization#GO:0008104;cytokinesis#GO:0000910 microtubule cytoskeleton#GO:0015630;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000025014.3|UniProtKB=F6SWK4 F6SWK4 FOXL3 PTHR11829:SF211 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000008837.4|UniProtKB=F6XUK5 F6XUK5 SNX33 PTHR45827:SF3 SORTING NEXIN SORTING NEXIN-33 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;membrane invagination#GO:0010324;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;cell cycle process#GO:0022402;cell division#GO:0051301;cell cycle#GO:0007049;cellular component organization#GO:0016043;endocytosis#GO:0006897;cytokinetic process#GO:0032506;cytokinesis#GO:0000910;plasma membrane organization#GO:0007009;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;cellular localization#GO:0051641 vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000015685.3|UniProtKB=F7E1B1 F7E1B1 TRIM54 PTHR24103:SF596 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 54 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000003053.4|UniProtKB=F6PP12 F6PP12 LOC100019688 PTHR21444:SF17 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 STIMULATED BY RETINOIC ACID GENE 6 PROTEIN-LIKE transmembrane transport#GO:0055085;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;transport#GO:0006810;vitamin transport#GO:0051180;lipid transport#GO:0006869;macromolecule localization#GO:0033036;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000027755.2|UniProtKB=K7E2G0 K7E2G0 LOC103093588 PTHR45656:SF21 PROTEIN CBR-CLEC-78 CD55 MOLECULE (CROMER BLOOD GROUP) MONDO|Ensembl=ENSMODG00000016822.3|UniProtKB=F7FIH3 F7FIH3 GINM1 PTHR28549:SF1 GLYCOPROTEIN INTEGRAL MEMBRANE PROTEIN 1 GLYCOPROTEIN INTEGRAL MEMBRANE PROTEIN 1 MONDO|Ensembl=ENSMODG00000018190.3|UniProtKB=F7B788 F7B788 B4GALT4 PTHR19300:SF9 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 4 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000019671.4|UniProtKB=F6TTY4 F6TTY4 TTLL11 PTHR12241:SF154 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL11 binding#GO:0005488;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;cilium#GO:0005929;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000010468.2|UniProtKB=F7F7I6 F7F7I6 PTHR48099:SF15 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED BIFUNCTIONAL METHYLENETETRAHYDROFOLATE DEHYDROGENASE_CYCLOHYDROLASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824 tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;tetrahydrofolate metabolic process#GO:0046653;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;biosynthetic process#GO:0009058;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 MONDO|Ensembl=ENSMODG00000021076.4|UniProtKB=A0A5F8HB72 A0A5F8HB72 URB1 PTHR13500:SF0 NUCLEOLAR PRERIBOSOMAL-ASSOCIATED PROTEIN 1 NUCLEOLAR PRE-RIBOSOMAL-ASSOCIATED PROTEIN 1 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000041401.1|UniProtKB=A0A5F8H8V5 A0A5F8H8V5 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025627.3|UniProtKB=F6XWT1 F6XWT1 TMEM71 PTHR35255:SF1 TRANSMEMBRANE PROTEIN 71 TRANSMEMBRANE PROTEIN 71 MONDO|Ensembl=ENSMODG00000051031.1|UniProtKB=A0A5F8GBW7 A0A5F8GBW7 PTHR10442:SF25 40S RIBOSOMAL PROTEIN S21 SMALL RIBOSOMAL SUBUNIT PROTEIN ES21 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;rRNA processing#GO:0006364;translation#GO:0006412;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000024470.1|UniProtKB=Q28463 Q28463 RAG1 PTHR11539:SF0 VDJ RECOMBINATION ACTIVATING PROTEIN 1 RAG1 V(D)J RECOMBINATION-ACTIVATING PROTEIN 1 DNA metabolism protein#PC00009;endodeoxyribonuclease#PC00093 MONDO|Ensembl=ENSMODG00000001113.4|UniProtKB=F7DPD2 F7DPD2 OPTC PTHR46269:SF4 EPIPHYCAN-RELATED OPTICIN cellular component organization#GO:0016043;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;skeletal system development#GO:0001501;cartilage development#GO:0051216;system development#GO:0048731;external encapsulating structure organization#GO:0045229;cellular process#GO:0009987;bone development#GO:0060348;multicellular organismal process#GO:0032501;tissue development#GO:0009888;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;connective tissue development#GO:0061448 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000022760.3|UniProtKB=H9H8U2 H9H8U2 GPR182 PTHR24226:SF0 G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1 ATYPICAL CHEMOKINE RECEPTOR 5 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000037925.1|UniProtKB=A0A5F8HEN6 A0A5F8HEN6 RBM24 PTHR48024:SF10 GEO13361P1-RELATED RNA-BINDING PROTEIN 24 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cell differentiation#GO:0045597;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000000319.5|UniProtKB=A0A5F8G4Q6 A0A5F8G4Q6 USP38 PTHR24006:SF710 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 38 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000047579.1|UniProtKB=A0A5F8GJH8 A0A5F8GJH8 ATOH8 PTHR19290:SF102 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED TRANSCRIPTION FACTOR ATOH8 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000001825.4|UniProtKB=F6T584 F6T584 CUL1 PTHR11932:SF168 CULLIN CULLIN-1 structural molecule activity#GO:0005198;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515;protein complex scaffold activity#GO:0140378;enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>Cul-1#P01239 MONDO|Ensembl=ENSMODG00000049003.1|UniProtKB=A0A0A7DTS6 A0A0A7DTS6 BID PTHR10424:SF82 VIRAL ENVELOPE PROTEIN ENVELOPE POLYPROTEIN syncytium formation by cell-cell fusion#GO:0000768;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;striated muscle cell differentiation#GO:0051146;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;cell differentiation#GO:0030154;muscle structure development#GO:0061061;myoblast fusion#GO:0007520;muscle cell differentiation#GO:0042692;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000050834.1|UniProtKB=A0A5F8GBP6 A0A5F8GBP6 DUSP22 PTHR45948:SF3 DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0269404-RELATED DUAL SPECIFICITY PROTEIN PHOSPHATASE 22 protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of JNK cascade#GO:0046330;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;transforming growth factor beta receptor signaling pathway#GO:0007179;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;regulation of JNK cascade#GO:0046328;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;response to transforming growth factor beta#GO:0071559;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;positive regulation of MAPK cascade#GO:0043410 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 MONDO|Ensembl=ENSMODG00000020400.4|UniProtKB=F7AYL0 F7AYL0 SLC45A2 PTHR19432:SF34 SUGAR TRANSPORTER MEMBRANE-ASSOCIATED TRANSPORTER PROTEIN secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144 secondary metabolic process#GO:0019748;melanin biosynthetic process#GO:0042438;pigment biosynthetic process#GO:0046148;pigmentation#GO:0043473;metabolic process#GO:0008152;secondary metabolite biosynthetic process#GO:0044550;biosynthetic process#GO:0009058;phenol-containing compound metabolic process#GO:0018958;developmental pigmentation#GO:0048066;cellular process#GO:0009987;phenol-containing compound biosynthetic process#GO:0046189;pigment metabolic process#GO:0042440 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;melanosome#GO:0042470;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000007708.4|UniProtKB=F7EVH3 F7EVH3 UNC13D PTHR45999:SF3 UNC-13-4A, ISOFORM B PROTEIN UNC-13 HOMOLOG D localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810 intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;transport vesicle#GO:0030133;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 Synaptic vesicle trafficking#P05734>Munc13#P05773 MONDO|Ensembl=ENSMODG00000043465.1|UniProtKB=A0A5F8GUF0 A0A5F8GUF0 PTHR24381:SF435 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 275 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015487.4|UniProtKB=F6WET4 F6WET4 EP400 PTHR46459:SF1 E1A-BINDING PROTEIN P400-RELATED E1A-BINDING PROTEIN P400 chromatin binding#GO:0003682;binding#GO:0005488 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 Swr1 complex#GO:0000812;catalytic complex#GO:1902494;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;H4 histone acetyltransferase complex#GO:1902562;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;protein acetyltransferase complex#GO:0031248;intracellular organelle lumen#GO:0070013;acetyltransferase complex#GO:1902493;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000016524.4|UniProtKB=F7F1V1 F7F1V1 PKMYT1 PTHR11042:SF183 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 reproductive process#GO:0022414;cellular process#GO:0009987;sexual reproduction#GO:0019953;cell cycle#GO:0007049;meiotic cell cycle#GO:0051321 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000042113.1|UniProtKB=Q2AB98 Q2AB98 T2R21 PTHR11394:SF58 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 7 molecular transducer activity#GO:0060089;bitter taste receptor activity#GO:0033038;taste receptor activity#GO:0008527;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of taste#GO:0050909;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004070.4|UniProtKB=A0A5F8GMS0 A0A5F8GMS0 ANKRD45 PTHR24180:SF14 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 45 cell population proliferation#GO:0008283;cellular process#GO:0009987 midbody#GO:0030496;cellular anatomical structure#GO:0110165 kinase modulator#PC00140;kinase inhibitor#PC00139 MONDO|Ensembl=ENSMODG00000012282.2|UniProtKB=A0A5F8H5I2 A0A5F8H5I2 GALR1 PTHR24230:SF31 G-PROTEIN COUPLED RECEPTOR GALANIN RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000047741.1|UniProtKB=A0A5F8GQL3 A0A5F8GQL3 LOC103099919 PTHR10188:SF16 L-ASPARAGINASE N(4)-(BETA-N-ACETYLGLUCOSAMINYL)-L-ASPARAGINASE- LIKE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000025723.3|UniProtKB=F6T2L3 F6T2L3 PTHR24024:SF45 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A SCAVENGER RECEPTOR CLASS A MEMBER 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187 homeostatic process#GO:0042592;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;complement activation#GO:0006956;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of endocytosis#GO:0045807;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;defense response#GO:0006952;multicellular organismal-level homeostasis#GO:0048871;innate immune response#GO:0045087;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;positive regulation of cellular component organization#GO:0051130;immune system process#GO:0002376;activation of immune response#GO:0002253;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of endocytosis#GO:0030100;immune effector process#GO:0002252;chemical homeostasis#GO:0048878;humoral immune response#GO:0006959;regulation of localization#GO:0032879;regulation of transport#GO:0051049 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211;surfactant#PC00212 MONDO|Ensembl=ENSMODG00000019346.3|UniProtKB=H9H7B7 H9H7B7 PAFAH1B3 PTHR11852:SF2 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT ALPHA1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;carboxylic ester hydrolase activity#GO:0052689;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;hydrolase activity#GO:0016787 reproductive process#GO:0022414;gamete generation#GO:0007276;male gamete generation#GO:0048232;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502 catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000013457.4|UniProtKB=F7FZ77 F7FZ77 PARL PTHR43731:SF14 RHOMBOID PROTEASE PRESENILIN-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000017377.3|UniProtKB=F6VI96 F6VI96 PTHR13581:SF5 MRG-BINDING PROTEIN MRG_MORF4L-BINDING PROTEIN regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000017234.3|UniProtKB=F6WHL4 F6WHL4 VEGFD PTHR12025:SF11 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR D binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;molecular function activator activity#GO:0140677;protein binding#GO:0005515;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 multicellular organism development#GO:0007275;positive regulation of response to external stimulus#GO:0032103;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cell surface receptor signaling pathway#GO:0007166;regulation of response to external stimulus#GO:0032101;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;angiogenesis#GO:0001525;cellular response to growth factor stimulus#GO:0071363;sprouting angiogenesis#GO:0002040;animal gross anatomical part developmental process#GO:0160108;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;regulation of chemotaxis#GO:0050920;vascular endothelial growth factor receptor signaling pathway#GO:0048010;positive regulation of cell motility#GO:2000147;response to endogenous stimulus#GO:0009719;response to abiotic stimulus#GO:0009628;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to hypoxia#GO:0001666;positive regulation of locomotion#GO:0040017;regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;regulation of cell motility#GO:2000145;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;positive regulation of chemotaxis#GO:0050921;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of leukocyte migration#GO:0002685;response to growth factor#GO:0070848;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000005077.3|UniProtKB=F7A4K8 F7A4K8 SLC7A6 PTHR11785:SF398 AMINO ACID TRANSPORTER Y+L AMINO ACID TRANSPORTER 2 basic amino acid transmembrane transporter activity#GO:0015174;L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 amino acid transport#GO:0006865;cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000028160.2|UniProtKB=A0A5F8GLX4 A0A5F8GLX4 PTHR35088:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 178 COILED-COIL DOMAIN-CONTAINING PROTEIN 178 MONDO|Ensembl=ENSMODG00000022869.2|UniProtKB=A0A5F8HGS1 A0A5F8HGS1 PTHR21141:SF120 60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN P2 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000045657.1|UniProtKB=A0A5F8H1I9 A0A5F8H1I9 TMEM258 PTHR13636:SF0 TRANSMEMBRANE PROTEIN 258 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT TMEM258 binding#GO:0005488;protein-containing complex binding#GO:0044877 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;response to stress#GO:0006950 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 MONDO|Ensembl=ENSMODG00000051185.1|UniProtKB=K7DZC0 K7DZC0 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000029650.2|UniProtKB=K7E6B6 K7E6B6 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000006751.3|UniProtKB=F7CCQ3 F7CCQ3 PTHR14186:SF14 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED KAZAL-TYPE SERINE PROTEASE INHIBITOR DOMAIN-CONTAINING PROTEIN 1 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000017250.2|UniProtKB=F6TKQ9 F6TKQ9 PLAGL1 PTHR24390:SF64 ZINC FINGER PROTEIN PLEIOMORPHIC ADENOMA GENE-LIKE 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000000714.3|UniProtKB=F6W6G1 F6W6G1 PTHR21553:SF26 ALMS1-RELATED CENTROSOMAL PROTEIN 295 regulation of microtubule-based process#GO:0032886;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of organelle assembly#GO:1902115;regulation of biological process#GO:0050789 cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000012806.3|UniProtKB=F7DYS1 F7DYS1 TCAP PTHR15143:SF0 TELETHONIN TELETHONIN structural molecule activity#GO:0005198;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 animal organ development#GO:0048513;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;heart development#GO:0007507;heart process#GO:0003015;muscle system process#GO:0003012;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;actomyosin structure organization#GO:0031032;skeletal muscle contraction#GO:0003009;circulatory system development#GO:0072359;cell differentiation#GO:0030154;developmental process#GO:0032502;muscle contraction#GO:0006936;detection of mechanical stimulus#GO:0050982;system process#GO:0003008;heart contraction#GO:0060047;response to external stimulus#GO:0009605;cellular developmental process#GO:0048869;cardiac muscle tissue development#GO:0048738;detection of stimulus#GO:0051606;tissue development#GO:0009888;blood circulation#GO:0008015;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;system development#GO:0048731;tissue morphogenesis#GO:0048729;myofibril assembly#GO:0030239;heart morphogenesis#GO:0003007;actin cytoskeleton organization#GO:0030036;striated muscle tissue development#GO:0014706;cellular anatomical entity morphogenesis#GO:0032989;muscle organ development#GO:0007517;anatomical structure formation involved in morphogenesis#GO:0048646;protein-containing complex organization#GO:0043933;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cardiac muscle cell differentiation#GO:0055007;nervous system process#GO:0050877;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;anatomical structure morphogenesis#GO:0009653;protein-containing complex assembly#GO:0065003;response to abiotic stimulus#GO:0009628;cell development#GO:0048468;response to stimulus#GO:0050896;actin filament organization#GO:0007015;response to mechanical stimulus#GO:0009612;multicellular organismal process#GO:0032501;actin filament-based process#GO:0030029;neuromuscular process#GO:0050905;cellular component assembly involved in morphogenesis#GO:0010927;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;striated muscle contraction#GO:0006941;muscle structure development#GO:0061061;animal organ morphogenesis#GO:0009887 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular organelle#GO:0043229;I band#GO:0031674;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;Z disc#GO:0030018;contractile muscle fiber#GO:0043292 MONDO|Ensembl=ENSMODG00000005724.2|UniProtKB=F6TN44 F6TN44 PTHR19367:SF24 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 8-4 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000008087.2|UniProtKB=F6Z9J3 F6Z9J3 TOMT PTHR43836:SF1 CATECHOL O-METHYLTRANSFERASE 1-RELATED TRANSMEMBRANE O-METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;O-methyltransferase activity#GO:0008171;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;amine catabolic process#GO:0009310;catecholamine metabolic process#GO:0006584;amine metabolic process#GO:0009308;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958;catabolic process#GO:0009056;biogenic amine metabolic process#GO:0006576 methyltransferase#PC00155 MONDO|Ensembl=ENSMODG00000007348.4|UniProtKB=F7B0E6 F7B0E6 GEM PTHR45775:SF4 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C GTP-BINDING PROTEIN GEM carbohydrate derivative binding#GO:0097367;calcium channel regulator activity#GO:0005246;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;nucleotide binding#GO:0000166;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000009980.4|UniProtKB=F6Y7B7 F6Y7B7 SPART PTHR21068:SF55 SPARTIN SPARTIN regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of BMP signaling pathway#GO:0030514;cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;cell division#GO:0051301;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000020689.3|UniProtKB=F7DKG9 F7DKG9 CEP135 PTHR23159:SF18 CENTROSOMAL PROTEIN 2 CENTROSOMAL PROTEIN OF 135 KDA centriole replication#GO:0007099;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000015636.4|UniProtKB=F7FEL1 F7FEL1 DCP2 PTHR23114:SF17 M7GPPPN-MRNA HYDROLASE M7GPPPN-MRNA HYDROLASE pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;RNA decapping#GO:0110154;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 MONDO|Ensembl=ENSMODG00000006413.4|UniProtKB=F7FD57 F7FD57 MXRA8 PTHR44793:SF1 MATRIX REMODELING-ASSOCIATED PROTEIN 8 MATRIX REMODELING-ASSOCIATED PROTEIN 8 cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;developmental process#GO:0032502 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000045386.1|UniProtKB=A0A5F8GEC2 A0A5F8GEC2 VSTM5 PTHR12080:SF93 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 5 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of multicellular organismal process#GO:0051239;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;cell projection organization#GO:0030030;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;regulation of synapse organization#GO:0050807;positive regulation of cellular component organization#GO:0051130;immune system process#GO:0002376;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of synapse assembly#GO:0051963;filopodium assembly#GO:0046847;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of synapse assembly#GO:0051965;positive regulation of developmental process#GO:0051094;plasma membrane bounded cell projection assembly#GO:0120031;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;cell communication#GO:0007154;regulation of cell junction assembly#GO:1901888 axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000011169.3|UniProtKB=F6ZZP7 F6ZZP7 PTHR26450:SF64 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014496.4|UniProtKB=A0A5F8HE91 A0A5F8HE91 PTHR22978:SF5 B-CELL TRANSLOCATION GENE PROTEIN BTG4 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000029797.2|UniProtKB=F6WER8 F6WER8 PTHR47229:SF1 TRANSMEMBRANE PROTEIN 141 TRANSMEMBRANE PROTEIN 141 MONDO|Ensembl=ENSMODG00000006547.4|UniProtKB=F7BV62 F7BV62 PTHR43544:SF39 SHORT-CHAIN DEHYDROGENASE/REDUCTASE NADB-LER2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000013688.3|UniProtKB=F6QPQ5 F6QPQ5 NEURL2 PTHR12429:SF8 NEURALIZED NEURALIZED-LIKE PROTEIN 2 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neuralized#P01117 MONDO|Ensembl=ENSMODG00000050551.1|UniProtKB=A0A5F8GWC4 A0A5F8GWC4 MAN2B1 PTHR11607:SF72 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 glycosidase#PC00110;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000004374.4|UniProtKB=F6W8Y6 F6W8Y6 CA5A PTHR18952:SF89 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 5A, MITOCHONDRIAL hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 MONDO|Ensembl=ENSMODG00000020593.4|UniProtKB=A0A5F8GQ13 A0A5F8GQ13 GNPDA2 PTHR11280:SF9 GLUCOSAMINE-6-PHOSPHATE ISOMERASE GLUCOSAMINE-6-PHOSPHATE DEAMINASE 2 deaminase activity#GO:0019239;identical protein binding#GO:0042802;protein binding#GO:0005515;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;binding#GO:0005488;catalytic activity#GO:0003824 carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino sugar catabolic process#GO:0046348 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 isomerase#PC00135 N-acetylglucosamine metabolism#P02756>Glucosamine-6-phosphate deaminase#P03041 MONDO|Ensembl=ENSMODG00000003099.4|UniProtKB=F6PIT8 F6PIT8 SV2C PTHR23511:SF6 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2C regulation of neurotransmitter secretion#GO:0046928;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of synaptic vesicle exocytosis#GO:2000300;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of secretion#GO:0051046;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;regulation of transport#GO:0051049;regulation of localization#GO:0032879 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;presynapse#GO:0098793;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;intracellular vesicle#GO:0097708 MONDO|Ensembl=ENSMODG00000004101.2|UniProtKB=F6VFE4 F6VFE4 LOC100019436 PTHR48001:SF24 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040407.1|UniProtKB=F6TEF0 F6TEF0 LOC100020550 PTHR22848:SF0 WD40 REPEAT PROTEIN WD40 REPEAT-CONTAINING PROTEIN SMU1 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000011977.4|UniProtKB=F7B9U7 F7B9U7 PODNL1 PTHR45712:SF5 AGAP008170-PA PODOCAN-LIKE PROTEIN 1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000023612.3|UniProtKB=F7AZ05 F7AZ05 VN2R593 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005828.4|UniProtKB=F6U1V7 F6U1V7 CDKN2D PTHR24201:SF7 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CYCLIN-DEPENDENT KINASE 4 INHIBITOR D protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;kinase regulator activity#GO:0019207;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 kinase inhibitor#PC00139;protein-binding activity modulator#PC00095 p53 pathway#P00059>ARF#P01482;p53 pathway#P00059>ARF#G01574 MONDO|Ensembl=ENSMODG00000005022.3|UniProtKB=F7ERG0 F7ERG0 ISM1 PTHR10239:SF30 ISTHMIN-2 ISTHMIN-1 regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of anatomical structure morphogenesis#GO:0022603;negative regulation of angiogenesis#GO:0016525;regulation of angiogenesis#GO:0045765;regulation of vasculature development#GO:1901342 MONDO|Ensembl=ENSMODG00000038117.1|UniProtKB=F7AVX8 F7AVX8 PTHR26453:SF601 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010097.3|UniProtKB=F6X591 F6X591 TTC32 PTHR47059:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 32 TETRATRICOPEPTIDE REPEAT PROTEIN 32 MONDO|Ensembl=ENSMODG00000008423.4|UniProtKB=A0A5F8GBQ1 A0A5F8GBQ1 MASTL PTHR24356:SF438 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE GREATWALL kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of mitotic cell cycle#GO:0007346;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000027552.2|UniProtKB=F7FZU8 F7FZU8 PTHR33426:SF36 C2H2-TYPE DOMAIN-CONTAINING PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000001174.4|UniProtKB=A0A5F8G893 A0A5F8G893 TMCO5A PTHR22422:SF7 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 5B-RELATED TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 5A MONDO|Ensembl=ENSMODG00000037229.1|UniProtKB=A0A5F8HDZ6 A0A5F8HDZ6 PTHR26453:SF44 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1330-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013272.4|UniProtKB=F7D9H0 F7D9H0 REEP5 PTHR12300:SF93 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 5 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000020974.3|UniProtKB=F6S5V2 F6S5V2 PTHR23138:SF94 RAN BINDING PROTEIN RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;nuclear transport#GO:0051169;nuclear export#GO:0051168;intracellular transport#GO:0046907;transport#GO:0006810;nucleocytoplasmic transport#GO:0006913 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000041008.1|UniProtKB=A0A5F8H520 A0A5F8H520 HEBP1 PTHR11220:SF22 HEME-BINDING PROTEIN-RELATED HEME-BINDING PROTEIN 1 tetrapyrrole binding#GO:0046906;heme binding#GO:0020037;binding#GO:0005488 MONDO|Ensembl=ENSMODG00000012576.2|UniProtKB=F6PKR6 F6PKR6 LOC100618367 PTHR26453:SF238 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10N1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000049852.1|UniProtKB=A0A5F8GG38 A0A5F8GG38 PTHR10064:SF1 60S RIBOSOMAL PROTEIN L22 RIBOSOMAL PROTEIN EL22-LIKE binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000011468.3|UniProtKB=F6W0B8 F6W0B8 PTHR10489:SF655 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR-LIKE 2 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375 response to stress#GO:0006950;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to external stimulus#GO:0009605;defense response#GO:0006952;calcium-mediated signaling#GO:0019722;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;signaling#GO:0023052;locomotion#GO:0040011;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cell communication#GO:0007154;cell chemotaxis#GO:0060326;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 MONDO|Ensembl=ENSMODG00000043752.1|UniProtKB=A0A5F8G235 A0A5F8G235 MIA PTHR47312:SF1 MELANOMA-DERIVED GROWTH REGULATORY PROTEIN MELANOMA-DERIVED GROWTH REGULATORY PROTEIN cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 MONDO|Ensembl=ENSMODG00000009189.4|UniProtKB=F6ZNH6 F6ZNH6 SNX32 PTHR45850:SF3 SORTING NEXIN FAMILY MEMBER SORTING NEXIN-32 cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000025569.3|UniProtKB=F6UHQ4 F6UHQ4 PTHR11716:SF56 PHOSPHOLIPASE A2 FAMILY MEMBER GROUP IIE SECRETORY PHOSPHOLIPASE A2 lipid binding#GO:0008289;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;A2-type glycerophospholipase activity#GO:0004623;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;cation binding#GO:0043169;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;small molecule binding#GO:0036094;lipase activity#GO:0016298;ion binding#GO:0043167;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phospholipid binding#GO:0005543 phospholipid metabolic process#GO:0006644;phosphatidylcholine metabolic process#GO:0046470;phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000007927.5|UniProtKB=A0A5F8G6I1 A0A5F8G6I1 VCPIP1 PTHR14843:SF2 DEUBIQUITINATING PROTEIN VCIP135 DEUBIQUITINATING PROTEIN VCPIP1 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;endoplasmic reticulum membrane organization#GO:0090158;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;cellular process#GO:0009987;membrane fusion#GO:0061025;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to stress#GO:0006950;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;Golgi organization#GO:0007030;cellular response to stimulus#GO:0051716;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000021481.4|UniProtKB=F7G364 F7G364 COLEC12 PTHR22803:SF146 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED COLLECTIN-12 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000016852.3|UniProtKB=F6QH47 F6QH47 PTHR22803:SF116 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED REGENERATING ISLET-DERIVED PROTEIN 3-GAMMA hormone activity#GO:0005179;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 response to hormone#GO:0009725;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;response to other organism#GO:0051707;biological regulation#GO:0065007;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;defense response#GO:0006952;response to external stimulus#GO:0009605;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;immune system process#GO:0002376;response to oxygen-containing compound#GO:1901700;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;regulation of cell population proliferation#GO:0042127;response to nitrogen compound#GO:1901698 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000024999.3|UniProtKB=F7ED75 F7ED75 PTHR23023:SF74 DIMETHYLANILINE MONOOXYGENASE DIMETHYLANILINE MONOOXYGENASE [N-OXIDE-FORMING] 4 oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000039092.1|UniProtKB=F7BRF0 F7BRF0 LOC100030436 PTHR26452:SF310 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024123.2|UniProtKB=F6QET3 F6QET3 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001984.3|UniProtKB=F6RID9 F6RID9 PNPT1 PTHR11252:SF0 POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640 mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;mitochondrial RNA 3'-end processing#GO:0000965;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 nucleotidyltransferase#PC00174 MONDO|Ensembl=ENSMODG00000042795.1|UniProtKB=A0A5F8GT28 A0A5F8GT28 PTHR11431:SF47 FERRITIN FERRITIN LIGHT CHAIN metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;iron ion binding#GO:0005506;ferrous iron binding#GO:0008198 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 storage protein#PC00210 MONDO|Ensembl=ENSMODG00000006137.4|UniProtKB=F7BT12 F7BT12 PTHR12198:SF5 HOMEOBOX PROTEIN PROSPERO/PROX-1/CEH-26 PROSPERO HOMEOBOX PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000014960.3|UniProtKB=F7D0A6 F7D0A6 MAP2K7 PTHR48013:SF17 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 7 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 stress-activated MAPK cascade#GO:0051403;cellular response to stress#GO:0033554;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052 non-receptor serine/threonine protein kinase#PC00167 Huntington disease#P00029>MAPKK7#P00784;Apoptosis signaling pathway#P00006>MKK7#P00312;FGF signaling pathway#P00021>MKK4,7#P00637;EGF receptor signaling pathway#P00018>MKK4,7#P00555;Ras Pathway#P04393>MKK4/7#P04565;Gonadotropin-releasing hormone receptor pathway#P06664>MKK4/7#P06760 MONDO|Ensembl=ENSMODG00000006713.6|UniProtKB=A0A5F8H838 A0A5F8H838 MIB2 PTHR24202:SF4 E3 UBIQUITIN-PROTEIN LIGASE MIB2 E3 UBIQUITIN-PROTEIN LIGASE MIB2-RELATED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000010064.4|UniProtKB=F6Y546 F6Y546 FAM171A1 PTHR31626:SF1 SUSHI DOMAIN-CONTAINING PROTEIN PROTEIN FAM171A1 actin filament bundle assembly#GO:0051017;regulation of biological process#GO:0050789;actin filament bundle organization#GO:0061572;regulation of cell shape#GO:0008360;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;regulation of developmental process#GO:0050793;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;regulation of biological quality#GO:0065008;stress fiber assembly#GO:0043149;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component assembly#GO:0022607;contractile actin filament bundle assembly#GO:0030038;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000010001.4|UniProtKB=A0A5F8HD17 A0A5F8HD17 ABR PTHR23182:SF5 BREAKPOINT CLUSTER REGION PROTEIN BCR ACTIVE BREAKPOINT CLUSTER REGION-RELATED PROTEIN enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789 cell junction#GO:0030054;postsynaptic density#GO:0014069;postsynaptic specialization#GO:0099572;organelle#GO:0043226;asymmetric synapse#GO:0032279;glutamatergic synapse#GO:0098978;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944 G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000000312.4|UniProtKB=F6VV34 F6VV34 PTHR13817:SF181 TITIN IMMUNOGLOBULIN LIKE AND FIBRONECTIN TYPE III DOMAIN CONTAINING 1 structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;supramolecular fiber organization#GO:0097435;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029 supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;A band#GO:0031672;contractile muscle fiber#GO:0043292;sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;M band#GO:0031430;intracellular organelle#GO:0043229 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000023998.2|UniProtKB=F7ARZ9 F7ARZ9 PTHR26450:SF177 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52I1-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000007733.5|UniProtKB=F6W721 F6W721 ZIC5 PTHR19818:SF69 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000020533.4|UniProtKB=F7ENF5 F7ENF5 FAM114A1 PTHR12842:SF4 FI01459P PROTEIN NOXP20 MONDO|Ensembl=ENSMODG00000036524.1|UniProtKB=F7AHD1 F7AHD1 PTHR26452:SF974 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5W2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000013141.4|UniProtKB=F7AZC9 F7AZC9 POU2F3 PTHR11636:SF81 POU DOMAIN POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000021073.4|UniProtKB=A0A5F8GRI3 A0A5F8GRI3 SYNJ1 PTHR11200:SF158 INOSITOL 5-PHOSPHATASE POLYPHOSPHATIDYLINOSITOL PHOSPHATASE SYNJ1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle endocytosis#GO:0048488;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;endocytosis#GO:0006897;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport in synapse#GO:0099003;cellular localization#GO:0051641;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179 cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;membrane#GO:0016020;presynapse#GO:0098793 hydrolase#PC00121;phosphatase#PC00181 Huntington disease#P00029>Synaptojanin#P00804 MONDO|Ensembl=ENSMODG00000007820.4|UniProtKB=F7ETQ7 F7ETQ7 ACTR10 PTHR11937:SF14 ACTIN ACTIN-RELATED PROTEIN 10 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;mitochondrion localization#GO:0051646;microtubule-based process#GO:0007017;axo-dendritic transport#GO:0008088;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;organelle localization#GO:0051640;axonal transport#GO:0098930;retrograde axonal transport#GO:0008090;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630 actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000038319.1|UniProtKB=A0A5F8HA70 A0A5F8HA70 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000014839.4|UniProtKB=A0A5F8GF23 A0A5F8GF23 PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN peptide binding#GO:0042277;antigen binding#GO:0003823;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of immune system process#GO:0002684;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;response to stimulus#GO:0050896;positive regulation of adaptive immune response#GO:0002821;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000009278.4|UniProtKB=F7CR53 F7CR53 ANO5 PTHR12308:SF23 ANOCTAMIN ANOCTAMIN-5 intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215 regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid transport#GO:0015914;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000007233.3|UniProtKB=F6WCA0 F6WCA0 PTHR11905:SF167 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN A DISINTEGRIN AND METALLOPEPTIDASE DOMAIN 4-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 proteolysis#GO:0006508;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;reproductive system development#GO:0061458;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;reproductive structure development#GO:0048608;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;male sex differentiation#GO:0046661;metabolic process#GO:0008152;development of primary male sexual characteristics#GO:0046546;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;animal organ development#GO:0048513;male gonad development#GO:0008584;sex differentiation#GO:0007548;cellular process#GO:0009987;gonad development#GO:0008406;multicellular organismal process#GO:0032501 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000028035.2|UniProtKB=K7E0Y3 K7E0Y3 LOC100011905 PTHR11214:SF151 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000005411.5|UniProtKB=F7FVN9 F7FVN9 ARHGAP30 PTHR15729:SF12 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 30 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000010173.4|UniProtKB=F6TA30 F6TA30 SNAI2 PTHR24388:SF42 ZINC FINGER PROTEIN ZINC FINGER PROTEIN SNAI2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000015548.4|UniProtKB=F6SKJ8 F6SKJ8 PTHR45852:SF1 SER/THR-PROTEIN KINASE RIO2 SERINE_THREONINE-PROTEIN KINASE RIO2 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000015937.4|UniProtKB=F6Z351 F6Z351 C8H2orf80 PTHR36296:SF1 GAMMA-CRYSTALLIN A CHROMOSOME 15 C2ORF80 HOMOLOG structural protein#PC00211 MONDO|Ensembl=ENSMODG00000005225.4|UniProtKB=F6YFD3 F6YFD3 CIDEC PTHR12306:SF9 CELL DEATH ACTIVATOR CIDE LIPID TRANSFERASE CIDEC lipid transfer activity#GO:0120013;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215 organelle fusion#GO:0048284;lipid storage#GO:0019915;apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;programmed cell death#GO:0012501;cellular component organization or biogenesis#GO:0071840;lipid droplet organization#GO:0034389 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811 MONDO|Ensembl=ENSMODG00000047823.1|UniProtKB=A0A5F8GWM2 A0A5F8GWM2 KCNU1 PTHR10027:SF23 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN POTASSIUM CHANNEL SUBFAMILY U MEMBER 1 transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic ion-gated channel activity#GO:0022839;ligand-gated channel activity#GO:0022834;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;potassium ion transmembrane transporter activity#GO:0015079 transport#GO:0006810;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 postsynaptic membrane#GO:0045211;synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000004891.4|UniProtKB=F7C2F0 F7C2F0 PKHD1L1 PTHR46769:SF3 POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1 FIBROCYSTIN-L MONDO|Ensembl=ENSMODG00000010736.4|UniProtKB=F7G7A3 F7G7A3 RPA2 PTHR13989:SF16 REPLICATION PROTEIN A-RELATED REPLICATION FACTOR A PROTEIN 2 nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162 cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;site of double-strand break#GO:0035861;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;chromosome, telomeric region#GO:0000781;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;chromosome#GO:0005694;organelle lumen#GO:0043233;replisome#GO:0030894;replication fork#GO:0005657;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 DNA replication#P00017>RPA#P00537 MONDO|Ensembl=ENSMODG00000006987.4|UniProtKB=F6QA24 F6QA24 TMCC1 PTHR17613:SF11 CEREBRAL PROTEIN-11-RELATED TRANSMEMBRANE AND COILED-COIL DOMAINS PROTEIN 1 membrane fission#GO:0090148;organelle fission#GO:0048285;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;transport#GO:0006810;intracellular transport#GO:0046907;endosome organization#GO:0007032;vesicle organization#GO:0016050;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000014003.3|UniProtKB=F6VQW3 F6VQW3 U2AF1L4 PTHR12620:SF3 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT SPLICING FACTOR U2AF 26 KDA SUBUNIT RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;binding#GO:0005488;nucleic acid binding#GO:0003676 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000014814.4|UniProtKB=F7DLN9 F7DLN9 TRIM25 PTHR25465:SF77 B-BOX DOMAIN CONTAINING E3 UBIQUITIN_ISG15 LIGASE TRIM25 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000047045.1|UniProtKB=F7DQA8 F7DQA8 NOP10 PTHR13305:SF0 RIBOSOME BIOGENESIS PROTEIN NOP10 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 3 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;snRNA metabolic process#GO:0016073;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000006048.4|UniProtKB=F7FSL0 F7FSL0 GRHL2 PTHR11037:SF17 TRANSCRIPTION FACTOR CP2 GRAINYHEAD-LIKE PROTEIN 2 HOMOLOG DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;embryo development ending in birth or egg hatching#GO:0009792;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;multicellular organismal process#GO:0032501;tissue development#GO:0009888;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;tube development#GO:0035295;head development#GO:0060322;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;regulation of gene expression#GO:0010468;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000023568.2|UniProtKB=F7G1R2 F7G1R2 AP1AR PTHR34529:SF1 AP-1 COMPLEX-ASSOCIATED REGULATORY PROTEIN AP-1 COMPLEX-ASSOCIATED REGULATORY PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488 vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;establishment of localization in cell#GO:0051649;Golgi to endosome transport#GO:0006895;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;transport vesicle#GO:0030133;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000039583.1|UniProtKB=A0A5F8HAA6 A0A5F8HAA6 SAPCD2 PTHR14907:SF3 FI14130P SUPPRESSOR APC DOMAIN-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000042511.1|UniProtKB=A0A5F8G5F0 A0A5F8G5F0 PTHR14947:SF26 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 781 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000041124.1|UniProtKB=A0A5F8H9U1 A0A5F8H9U1 VN2R565 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027886.2|UniProtKB=K7E277 K7E277 PTHR11003:SF30 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 4 transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832 cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000012233.4|UniProtKB=F7GGF8 F7GGF8 ABI3 PTHR10460:SF7 ABL INTERACTOR FAMILY MEMBER ABI GENE FAMILY MEMBER 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 system development#GO:0048731;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;regulation of cell migration#GO:0030334;developmental process#GO:0032502;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of locomotion#GO:0040012;cell migration#GO:0016477;multicellular organismal process#GO:0032501;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lamellipodium#GO:0030027;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;cell leading edge#GO:0031252;actin-based cell projection#GO:0098858;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018370.4|UniProtKB=F6RFQ7 F6RFQ7 DDX11 PTHR11472:SF41 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER ATP-DEPENDENT DNA HELICASE DDX11-RELATED ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;cell cycle process#GO:0022402;cellular process#GO:0009987;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;DNA helicase#PC00011 MONDO|Ensembl=ENSMODG00000043313.1|UniProtKB=A0A5F8GV79 A0A5F8GV79 PTHR24381:SF478 ZINC FINGER PROTEIN ZFP14 ZINC FINGER PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000009981.2|UniProtKB=F6Y7A4 F6Y7A4 HGSNAT PTHR31061:SF37 LD22376P HEPARAN-ALPHA-GLUCOSAMINIDE N-ACETYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;glycoprotein metabolic process#GO:0009100;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 lysosomal membrane#GO:0005765;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000020144.3|UniProtKB=F7D5A6 F7D5A6 LOC100026123 PTHR26452:SF253 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10Q1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000044608.1|UniProtKB=A0A5F8HIX7 A0A5F8HIX7 PTHR12884:SF18 60S RIBOSOMAL PROTEIN L29 60S RIBOSOMAL PROTEIN L29 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000009305.4|UniProtKB=F6YX20 F6YX20 PTHR44324:SF4 WD40 REPEAT DOMAIN 95 WD40 REPEAT DOMAIN 95 MONDO|Ensembl=ENSMODG00000019496.3|UniProtKB=F6W9Y6 F6W9Y6 ID1 PTHR11723:SF4 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;nervous system development#GO:0007399 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000007102.4|UniProtKB=A0A5F8H0X5 A0A5F8H0X5 FMN2 PTHR13037:SF16 FORMIN FORMIN-2 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cellular process#GO:0009987;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;cytoskeleton#GO:0005856;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000020407.4|UniProtKB=F7BZD7 F7BZD7 NPR3 PTHR44755:SF1 NATRIURETIC PEPTIDE RECEPTOR 3-RELATED ATRIAL NATRIURETIC PEPTIDE RECEPTOR 3 hormone binding#GO:0042562;binding#GO:0005488;peptide hormone binding#GO:0017046;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002918.4|UniProtKB=F6PMU1 F6PMU1 PTHR11003:SF57 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 13 voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000045772.1|UniProtKB=K7E4U4 K7E4U4 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000019153.5|UniProtKB=F7BK59 F7BK59 MAP1S PTHR13843:SF11 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 1S tubulin binding#GO:0015631;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of microtubule cytoskeleton organization#GO:0070507;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis#GO:0000902;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;dendrite development#GO:0016358;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;axon development#GO:0061564;cellular developmental process#GO:0048869;regulation of microtubule polymerization or depolymerization#GO:0031110;regulation of protein depolymerization#GO:1901879;neurogenesis#GO:0022008;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of supramolecular fiber organization#GO:1902903;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;system development#GO:0048731;regulation of microtubule-based process#GO:0032886 organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;cell body#GO:0044297;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;neuron projection#GO:0043005;cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000027910.2|UniProtKB=K7DZR2 K7DZR2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024374.2|UniProtKB=F6ZST6 F6ZST6 LOC100020453 PTHR48002:SF45 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025341.2|UniProtKB=F6ZB73 F6ZB73 PTHR22902:SF15 SESQUIPEDALIAN SESQUIPEDALIAN-2 retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;metabolic process#GO:0008152;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;endosomal transport#GO:0016197;endosome organization#GO:0007032;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cytosolic transport#GO:0016482;localization#GO:0051179;cellular localization#GO:0051641 Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791;organelle subcompartment#GO:0031984;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000020330.2|UniProtKB=F7G7A9 F7G7A9 PTHR23320:SF155 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 8 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000009228.4|UniProtKB=F7EE45 F7EE45 PPP5C PTHR45668:SF5 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 5 protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000027863.2|UniProtKB=K7E5V2 K7E5V2 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000012320.3|UniProtKB=F7EIM5 F7EIM5 PTGR3 PTHR43677:SF13 SHORT-CHAIN DEHYDROGENASE/REDUCTASE PROSTAGLANDIN REDUCTASE 3 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000044397.1|UniProtKB=A0A5F8HEZ6 A0A5F8HEZ6 OAF PTHR13423:SF2 OUT AT FIRST OUT AT FIRST PROTEIN HOMOLOG MONDO|Ensembl=ENSMODG00000051016.1|UniProtKB=A0A5F8GZQ3 A0A5F8GZQ3 CHCHD2 PTHR13523:SF3 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 2-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;mitochondrion organization#GO:0007005;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000004153.4|UniProtKB=F7FUN9 F7FUN9 CHL1 PTHR10075:SF43 BASIGIN RELATED CELL ADHESION MOLECULE L1-LIKE A ISOFORM X1 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000008610.4|UniProtKB=F6PHA8 F6PHA8 NUP210 PTHR23019:SF2 NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED NUCLEAR PORE MEMBRANE GLYCOPROTEIN 210 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;nucleus#GO:0005634;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 transporter#PC00227 MONDO|Ensembl=ENSMODG00000003519.4|UniProtKB=F7GBV9 F7GBV9 SLC25A28 PTHR45758:SF20 MITOFERRIN-1-RELATED MITOFERRIN-2 transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;iron ion transmembrane transporter activity#GO:0005381;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;iron ion transmembrane transport#GO:0034755;iron ion transport#GO:0006826;transport#GO:0006810;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000018972.3|UniProtKB=F7FPK7 F7FPK7 DLK2 PTHR24044:SF423 NOTCH LIGAND FAMILY MEMBER PROTEIN DELTA HOMOLOG 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000002042.4|UniProtKB=F6QCB9 F6QCB9 CPSF2 PTHR45922:SF2 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 MONDO|Ensembl=ENSMODG00000011019.4|UniProtKB=F6ZBS4 F6ZBS4 OPRD1 PTHR24229:SF2 NEUROPEPTIDES RECEPTOR DELTA-TYPE OPIOID RECEPTOR binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 Opioid proopiomelanocortin pathway#P05917>Mu or Delta receptor#P06004;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Enkephalin release#P05913>GPCR (i)#P05973;Opioid proenkephalin pathway#P05915>Mu or Delta receptor#P05985;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 MONDO|Ensembl=ENSMODG00000040141.1|UniProtKB=A0A5F8GG98 A0A5F8GG98 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000017704.4|UniProtKB=A0A5F8GH34 A0A5F8GH34 SOX5 PTHR45789:SF3 FI18025P1 TRANSCRIPTION FACTOR SOX-5 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of developmental process#GO:0050793;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000013453.4|UniProtKB=A0A5F8HC93 A0A5F8HC93 PAK4 PTHR48015:SF17 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE PAK 4 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 response to stress#GO:0006950;response to nutrient levels#GO:0031667;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837 MONDO|Ensembl=ENSMODG00000015617.3|UniProtKB=F6YFR5 F6YFR5 IFT172 PTHR15722:SF2 IFT140/172-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 172 HOMOLOG microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;microtubule-based transport#GO:0099111;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intraciliary transport particle B#GO:0030992;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000016195.4|UniProtKB=F7FY87 F7FY87 BAIAP3 PTHR45999:SF1 UNC-13-4A, ISOFORM B BAI1-ASSOCIATED PROTEIN 3 binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515 regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of cellular process#GO:0050794;regulation of neurotransmitter secretion#GO:0046928;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;positive regulation of signaling#GO:0023056;regulation of secretion#GO:0051046;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;positive regulation of synaptic transmission#GO:0050806;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;positive regulation of secretion#GO:0051047 recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;cell periphery#GO:0071944;vesicle membrane#GO:0012506;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;secretory vesicle#GO:0099503;plasma membrane#GO:0005886;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000000764.4|UniProtKB=F6SSW2 F6SSW2 KCNK9 PTHR11003:SF75 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 9 voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 5HT3 type receptor mediated signaling pathway#P04375>K+ channel#P04425;Dopamine receptor mediated signaling pathway#P05912>K+ channel#P05957;Opioid proenkephalin pathway#P05915>K+ channel#P05990;Nicotine pharmacodynamics pathway#P06587>KCNK3/9#P06605;5HT4 type receptor mediated signaling pathway#P04376>K+ channel#P04426;Opioid proopiomelanocortin pathway#P05917>K+ channel#P06009;5HT1 type receptor mediated signaling pathway#P04373>K+ channel#P04407;5HT2 type receptor mediated signaling pathway#P04374>K+ channel#P04413 MONDO|Ensembl=ENSMODG00000037201.1|UniProtKB=A0A5F8H8A2 A0A5F8H8A2 SRD5A3 PTHR14624:SF0 DFG10 PROTEIN POLYPRENAL REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;phosphorus metabolic process#GO:0006793;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycoprotein metabolic process#GO:0009100;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;organophosphate metabolic process#GO:0019637;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000000839.4|UniProtKB=F6RLI6 F6RLI6 NRDC PTHR43690:SF40 NARDILYSIN NARDILYSIN metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000000979.4|UniProtKB=F7ESE1 F7ESE1 SLC29A4 PTHR10332:SF93 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 4 nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleoside transmembrane transporter activity#GO:0005337;carbohydrate derivative transmembrane transporter activity#GO:1901505;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoamine transmembrane transporter activity#GO:0008504 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000024598.2|UniProtKB=F6PTQ6 F6PTQ6 FGL2 PTHR19143:SF189 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBROLEUKIN cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000000520.4|UniProtKB=A0A5F8GNG1 A0A5F8GNG1 ZNF827 PTHR24403:SF62 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 827 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000049709.1|UniProtKB=A0A5F8GD58 A0A5F8GD58 PTHR16717:SF4 CYTOCHROME C OXIDASE POLYPEPTIDE VIII CYTOCHROME C OXIDASE SUBUNIT 8B, MITOCHONDRIAL protein-containing complex#GO:0032991;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxidase#PC00175;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000037880.1|UniProtKB=A0A5F8H1S6 A0A5F8H1S6 PTHR26453:SF156 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013614.4|UniProtKB=F6RM83 F6RM83 SEMA6A PTHR11036:SF12 SEMAPHORIN SEMAPHORIN-6A signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;regulation of neuron migration#GO:2001222;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;axon development#GO:0061564;axon guidance#GO:0007411;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000019268.4|UniProtKB=A0A5F8H3I8 A0A5F8H3I8 SMARCAD1 PTHR10799:SF964 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A CONTAINING DEAD_H BOX 1 binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stress#GO:0006950;heterochromatin organization#GO:0070828;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;heterochromatin formation#GO:0031507;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;DNA damage response#GO:0006974;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;DNA double-strand break processing#GO:0000729;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 DNA helicase#PC00011;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000019493.4|UniProtKB=F6W9Z1 F6W9Z1 PTHR10504:SF84 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED BACTERICIDAL PERMEABILITY-INCREASING PROTEIN lipopolysaccharide binding#GO:0001530;carbohydrate derivative binding#GO:0097367;binding#GO:0005488;lipid binding#GO:0008289 cellular response to stimulus#GO:0051716;negative regulation of multicellular organismal process#GO:0051241;cellular response to biotic stimulus#GO:0071216;response to external biotic stimulus#GO:0043207;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to bacterium#GO:0009617;lipopolysaccharide-mediated signaling pathway#GO:0031663;cell communication#GO:0007154;negative regulation of macromolecule metabolic process#GO:0010605;immune response#GO:0006955;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;response to other organism#GO:0051707;negative regulation of cellular process#GO:0048523;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;negative regulation of cell activation#GO:0050866;regulation of biosynthetic process#GO:0009889;cellular response to molecule of bacterial origin#GO:0071219;innate immune response#GO:0045087;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;regulation of cell activation#GO:0050865;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;defense response to Gram-negative bacterium#GO:0050829;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;signal transduction#GO:0007165;regulation of macrophage activation#GO:0043030;cellular response to oxygen-containing compound#GO:1901701;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;negative regulation of leukocyte activation#GO:0002695;regulation of multicellular organismal process#GO:0051239;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;defense response to other organism#GO:0098542;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000023248.2|UniProtKB=F6XRS8 F6XRS8 S1PR1 PTHR22750:SF16 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 1 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;signal transduction#GO:0007165;tube development#GO:0035295;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;developmental process#GO:0032502;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;system development#GO:0048731;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000003544.4|UniProtKB=A0A5F8GEX6 A0A5F8GEX6 KIFAP3 PTHR15605:SF2 KINESIN-ASSOCIATED PROTEINS KINESIN-ASSOCIATED PROTEIN 3 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cilium organization#GO:0044782;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840 axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ciliary transition zone#GO:0035869;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000016226.4|UniProtKB=F7FLS4 F7FLS4 PTHR13250:SF1 TF-1 CELL APOPTOSIS RELATED PROTEIN-15 PROGRAMMED CELL DEATH PROTEIN 10 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular process#GO:0009987 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000004888.5|UniProtKB=A0A5F8H001 A0A5F8H001 PTHR10910:SF106 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN ADENOSINE DEAMINASE DOMAIN-CONTAINING PROTEIN 2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity, acting on RNA#GO:0140098;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;adenosine deaminase activity#GO:0004000;hydrolase activity#GO:0016787;RNA binding#GO:0003723;tRNA-specific adenosine deaminase activity#GO:0008251;double-stranded RNA binding#GO:0003725;nucleic acid binding#GO:0003676;binding#GO:0005488 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;base conversion or substitution editing#GO:0016553;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;adenosine to inosine editing#GO:0006382;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000006697.4|UniProtKB=F7DH73 F7DH73 BTAF1 PTHR36498:SF1 TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172 TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172 MONDO|Ensembl=ENSMODG00000007315.4|UniProtKB=F7EXX3 F7EXX3 FN3KRP PTHR12149:SF10 FRUCTOSAMINE 3 KINASE-RELATED PROTEIN KETOSAMINE-3-KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein repair#GO:0030091;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000005982.2|UniProtKB=F6VIN8 F6VIN8 PTHR10885:SF24 ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;organophosphate biosynthetic process#GO:0090407;isoprenoid metabolic process#GO:0006720 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777 isomerase#PC00135 MONDO|Ensembl=ENSMODG00000016089.4|UniProtKB=F7FZ45 F7FZ45 PPIA PTHR11071:SF490 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000025729.2|UniProtKB=F6T294 F6T294 ATP5MK PTHR34038:SF1 ATP SYNTHASE MEMBRANE SUBUNIT DAPIT, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT K, MITOCHONDRIAL membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803;proton-transporting ATP synthase complex#GO:0045259;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000014737.4|UniProtKB=A0A5F8G344 A0A5F8G344 PTHR11475:SF108 OXIDASE/PEROXIDASE MYELOPEROXIDASE antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000011515.4|UniProtKB=A0A5F8HEC8 A0A5F8HEC8 TIA1 PTHR10352:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G CYTOTOXIC GRANULE ASSOCIATED RNA BINDING PROTEIN TIA1 regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 MONDO|Ensembl=ENSMODG00000024387.2|UniProtKB=F6SRP8 F6SRP8 LOC100019902 PTHR48002:SF53 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C15 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024744.3|UniProtKB=F6TJD5 F6TJD5 PLSCR4 PTHR23248:SF28 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE 4 intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215 plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;localization#GO:0051179;lipid localization#GO:0010876;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000007752.5|UniProtKB=A0A5F8HBG2 A0A5F8HBG2 POLR3E PTHR12069:SF0 DNA-DIRECTED RNA POLYMERASES III 80 KDA POLYPEPTIDE RNA POLYMERASE III SUBUNIT 5 DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000043509.1|UniProtKB=A0A5F8GG43 A0A5F8GG43 GLTPD2 PTHR10219:SF19 GLYCOLIPID TRANSFER PROTEIN-RELATED GLYCOLIPID TRANSFER PROTEIN DOMAIN-CONTAINING PROTEIN 2 phospholipid binding#GO:0005543;transporter activity#GO:0005215;phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;ion binding#GO:0043167;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 transport#GO:0006810;lipid localization#GO:0010876;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;membrane organization#GO:0061024;ceramide transport#GO:0035627;lipid transport#GO:0006869 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cytosol#GO:0005829 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000006833.4|UniProtKB=F6PG40 F6PG40 PTHR43605:SF3 ACYL-COENZYME A SYNTHETASE ACYL-COENZYME A SYNTHETASE ACSM2B, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753 mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;ligase#PC00142 MONDO|Ensembl=ENSMODG00000011372.3|UniProtKB=F6SPV4 F6SPV4 PTHR36135:SF1 FIBROUS SHEATH CABYR-BINDING PROTEIN FIBROUS SHEATH CABYR-BINDING PROTEIN metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 regulation of primary metabolic process#GO:0080090;negative regulation of biological process#GO:0048519;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of biological process#GO:0050789;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;biological regulation#GO:0065007;negative regulation of protein metabolic process#GO:0051248;negative regulation of cellular process#GO:0048523;regulation of post-translational protein modification#GO:1901873;regulation of protein modification process#GO:0031399 9+2 motile cilium#GO:0097729;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;sperm principal piece#GO:0097228;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 MONDO|Ensembl=ENSMODG00000016831.5|UniProtKB=F6R2J2 F6R2J2 TAB2 PTHR46253:SF2 TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN TAB TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 2 binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;modification-dependent protein binding#GO:0140030;protein binding#GO:0005515 regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;heart development#GO:0007507;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;animal organ development#GO:0048513;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;positive regulation of signaling#GO:0023056;anatomical structure development#GO:0048856 p38 MAPK pathway#P05918>TAB2#P06033 MONDO|Ensembl=ENSMODG00000016285.5|UniProtKB=F6Y9T2 F6Y9T2 DDX27 PTHR24031:SF706 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX27-RELATED metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000028650.2|UniProtKB=K7E252 K7E252 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000011941.4|UniProtKB=F7DDV7 F7DDV7 TARS3 PTHR11451:SF38 THREONINE-TRNA LIGASE THREONINE--TRNA LIGASE 2, CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000007286.4|UniProtKB=A0A5F8GUL7 A0A5F8GUL7 EYA1 PTHR10190:SF11 EYES ABSENT PROTEIN PHOSPHATASE EYA1 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 inner ear development#GO:0048839;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of DNA repair#GO:0045739;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;sensory organ development#GO:0007423;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;cellular developmental process#GO:0048869;positive regulation of DNA metabolic process#GO:0051054;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;embryonic organ development#GO:0048568;anatomical structure development#GO:0048856;inner ear morphogenesis#GO:0042472;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;embryo development#GO:0009790;animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;sensory organ morphogenesis#GO:0090596;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;positive regulation of metabolic process#GO:0009893;ear development#GO:0043583;regulation of cellular response to stress#GO:0080135 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000044797.1|UniProtKB=A0A5F8HBV6 A0A5F8HBV6 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000023170.3|UniProtKB=F7D829 F7D829 GEMIN4 PTHR15571:SF2 GEM-ASSOCIATED PROTEIN 4 GEM-ASSOCIATED PROTEIN 4 spliceosomal snRNP assembly#GO:0000387;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;SMN complex#GO:0032797;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000009314.3|UniProtKB=F7GJZ2 F7GJZ2 TNIP1 PTHR31882:SF3 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER TNFAIP3-INTERACTING PROTEIN 1 binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;mitogen-activated protein kinase binding#GO:0051019 response to lipopolysaccharide#GO:0032496;regulation of MAPK cascade#GO:0043408;negative regulation of signal transduction#GO:0009968;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;cellular response to molecule of bacterial origin#GO:0071219;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;response to bacterium#GO:0009617;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;cellular response to biotic stimulus#GO:0071216 MONDO|Ensembl=ENSMODG00000037010.1|UniProtKB=A0A5F8HLI6 A0A5F8HLI6 PTHR12980:SF0 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX, SUBUNIT X CYTOCHROME B-C1 COMPLEX SUBUNIT 9 respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119 membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex III#GO:0045275 reductase#PC00198;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000040802.1|UniProtKB=A0A5F8GJB1 A0A5F8GJB1 LOC100617920 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000001524.4|UniProtKB=F7F413 F7F413 MAT1A PTHR11964:SF11 S-ADENOSYLMETHIONINE SYNTHETASE S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 nucleotidyltransferase#PC00174;transferase#PC00220 S-adenosylmethionine biosynthesis#P02773>S-Adenosyl methionine synthetase#P03143 MONDO|Ensembl=ENSMODG00000007049.4|UniProtKB=F6UFB1 F6UFB1 DOCK2 PTHR45653:SF6 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 2 guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 animal gross anatomical part developmental process#GO:0160108;cell-cell fusion#GO:0140253;developmental process#GO:0032502;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;syncytium formation by cell-cell fusion#GO:0000768;striated muscle cell differentiation#GO:0051146;myoblast fusion#GO:0007520;cellular process#GO:0009987;muscle cell differentiation#GO:0042692;cell motility#GO:0048870;muscle structure development#GO:0061061;cell migration#GO:0016477;cell differentiation#GO:0030154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000016441.4|UniProtKB=F7A4Z1 F7A4Z1 LOC103094872 PTHR19297:SF178 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE 7-RELATED acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000028654.2|UniProtKB=K7E0D2 K7E0D2 PTHR33064:SF44 POL PROTEIN RIBONUCLEASE H MONDO|Ensembl=ENSMODG00000024860.3|UniProtKB=F7A9L9 F7A9L9 PTHR48069:SF6 DIHYDROFOLATE REDUCTASE DIHYDROFOLATE REDUCTASE small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166 folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;tetrahydrofolate metabolic process#GO:0046653;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;tetrahydrofolate biosynthetic process#GO:0046654 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;reductase#PC00198 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948 MONDO|Ensembl=ENSMODG00000012935.4|UniProtKB=F7G1T5 F7G1T5 SCN3B PTHR10546:SF1 SODIUM CHANNEL SUBUNIT BETA-1 AND 3 SODIUM CHANNEL REGULATORY SUBUNIT BETA-3 molecular function regulator activity#GO:0098772;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;protein binding#GO:0005515;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325 system process#GO:0003008;heart contraction#GO:0060047;cardiac muscle cell contraction#GO:0086003;establishment of localization#GO:0051234;transport#GO:0006810;muscle contraction#GO:0006936;regulation of system process#GO:0044057;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;actin filament-based movement#GO:0030048;monoatomic cation transport#GO:0006812;localization#GO:0051179;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;regulation of heart contraction#GO:0008016;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;membrane depolarization#GO:0051899;actin-mediated cell contraction#GO:0070252;regulation of membrane potential#GO:0042391;regulation of multicellular organismal process#GO:0051239;monoatomic cation transmembrane transport#GO:0098655;cardiac muscle cell action potential involved in contraction#GO:0086002;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;heart process#GO:0003015;sodium ion transport#GO:0006814;muscle system process#GO:0003012;regulation of biological process#GO:0050789;action potential#GO:0001508 membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;sodium channel complex#GO:0034706 voltage-gated ion channel#PC00241;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000004894.3|UniProtKB=F7C2D1 F7C2D1 TLX2 PTHR45921:SF3 IP01054P T-CELL LEUKEMIA HOMEOBOX PROTEIN 2 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000036781.1|UniProtKB=A0A5F8GY93 A0A5F8GY93 PTHR24381:SF462 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 420 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000000179.2|UniProtKB=F6TGB4 F6TGB4 PTHR19282:SF455 TETRASPANIN TETRASPANIN-16 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020379.4|UniProtKB=F7F6D0 F7F6D0 AGXT2 PTHR45688:SF3 FAMILY NOT NAMED ALANINE--GLYOXYLATE AMINOTRANSFERASE 2, MITOCHONDRIAL MONDO|Ensembl=ENSMODG00000038832.1|UniProtKB=F7BNY8 F7BNY8 PTHR11426:SF238 HISTONE H3 HISTONE H3 mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic metaphase chromosome alignment#GO:0007080;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;kinetochore assembly#GO:0051382;nuclear division#GO:0000280;organelle localization#GO:0051640;organelle assembly#GO:0070925;organelle fission#GO:0048285;localization#GO:0051179;kinetochore organization#GO:0051383;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000046761.1|UniProtKB=A0A5F8HA13 A0A5F8HA13 PTHR24028:SF234 CADHERIN-87A PROTOCADHERIN GAMMA-A7 cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000005164.4|UniProtKB=F7E8A7 F7E8A7 PSMB5 PTHR11599:SF51 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-5 catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;proteasome complex#GO:0000502;cytosol#GO:0005829;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000004794.2|UniProtKB=F6VME0 F6VME0 PTHR19338:SF107 TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE 13 HOMOLOG MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM13 mitochondrion organization#GO:0007005;mitochondrial protein import pathway#GO:7770058;protein insertion into mitochondrial inner membrane#GO:0045039;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular transport#GO:0046907;transport#GO:0006810;mitochondrial transport#GO:0006839;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179 membrane-enclosed lumen#GO:0031974;mitochondrial envelope#GO:0005740;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;mitochondrial intermembrane space#GO:0005758;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000042646.1|UniProtKB=A0A5F8G898 A0A5F8G898 LOC100016193 PTHR48018:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 974 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000043990.1|UniProtKB=A0A5F8G703 A0A5F8G703 LOC103104714 PTHR11309:SF133 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 1 molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway#GO:0007166;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;non-canonical Wnt signaling pathway#GO:0035567;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>FrzB#P01461;Angiogenesis#P00005>FRP#P00237 MONDO|Ensembl=ENSMODG00000012698.4|UniProtKB=A0A5F8GZI1 A0A5F8GZI1 MBIP PTHR23404:SF3 MOLYBDOPTERIN SYNTHASE RELATED MAP3K12-BINDING INHIBITORY PROTEIN 1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000002952.4|UniProtKB=A0A5F8GNG3 A0A5F8GNG3 FXN PTHR16821:SF2 FRATAXIN FRATAXIN, MITOCHONDRIAL cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000014520.2|UniProtKB=F7ERQ3 F7ERQ3 ALLC PTHR12045:SF3 ALLANTOICASE INACTIVE ALLANTOICASE-RELATED Allantoin degradation#P02725>Allantoate amidohydrolase#P02821 MONDO|Ensembl=ENSMODG00000009760.4|UniProtKB=F6WT23 F6WT23 DIS3L PTHR23355:SF30 RIBONUCLEASE DIS3-LIKE EXONUCLEASE 1 RNA nuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175 negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070 catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 exoribonuclease#PC00099 MONDO|Ensembl=ENSMODG00000009593.4|UniProtKB=A0A5F8HJA7 A0A5F8HJA7 HOXD8 PTHR46166:SF1 HOMEOBOX DOMAIN-CONTAINING PROTEIN HOMEOBOX PROTEIN HOX-D8 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000001589.3|UniProtKB=F7BBD3 F7BBD3 MTERF2 PTHR15437:SF1 TRANSCRIPTION TERMINATION FACTOR, MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTOR 2, MITOCHONDRIAL double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 General transcription regulation#P00023>TTF2#P00661;Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 MONDO|Gene=PGB|UniProtKB=Q689Z7 Q689Z7 PGB PTHR47966:SF70 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSIN B catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 aspartic protease#PC00053;protease#PC00190 MONDO|Ensembl=ENSMODG00000002683.4|UniProtKB=F7CYN4 F7CYN4 PIGU PTHR13121:SF0 GPI TRANSAMIDASE COMPONENT PIG-U GPI-ANCHOR TRANSAMIDASE COMPONENT PIGU macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;GPI anchored protein biosynthesis#GO:0180046;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;caspase complex#GO:0008303;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 MONDO|Ensembl=ENSMODG00000015790.4|UniProtKB=A0A5F8HAJ8 A0A5F8HAJ8 PLCH1 PTHR10336:SF51 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE ETA-1 catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;cell-cell signaling#GO:0007267;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530 MONDO|Ensembl=ENSMODG00000023100.2|UniProtKB=F7EX04 F7EX04 CHST4 PTHR10704:SF40 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 4 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 amino sugar metabolic process#GO:0006040;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000012950.4|UniProtKB=F7DWN7 F7DWN7 CLMP PTHR44783:SF1 CXADR-LIKE MEMBRANE PROTEIN CXADR-LIKE MEMBRANE PROTEIN MONDO|Ensembl=ENSMODG00000049034.1|UniProtKB=A0A5F8GCY4 A0A5F8GCY4 LOC100619818 PTHR26452:SF52 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010355.4|UniProtKB=F6RPA6 F6RPA6 SRI PTHR46735:SF7 CALPAIN, SMALL SUBUNIT 1 A-RELATED SORCIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 MONDO|Ensembl=ENSMODG00000049098.1|UniProtKB=A0A5F8GWI8 A0A5F8GWI8 EIF2B1 PTHR45860:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA TRANSLATION INITIATION FACTOR EIF2B SUBUNIT ALPHA translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000007636.4|UniProtKB=F7BKK7 F7BKK7 GALK1 PTHR10457:SF7 MEVALONATE KINASE/GALACTOKINASE GALACTOKINASE-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 carbohydrate kinase#PC00065;metabolite interconversion enzyme#PC00262;kinase#PC00137;transferase#PC00220 Fructose galactose metabolism#P02744>Galactokinase#P02960 MONDO|Ensembl=ENSMODG00000017710.4|UniProtKB=F7FUI9 F7FUI9 RRAGC PTHR11259:SF6 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN C pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;response to starvation#GO:0042594;positive regulation of TOR signaling#GO:0032008;negative regulation of catabolic process#GO:0009895;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;negative regulation of autophagy#GO:0010507;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;lysosome#GO:0005764;nucleus#GO:0005634;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000048360.1|UniProtKB=A0A5F8HDI5 A0A5F8HDI5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007316.2|UniProtKB=F7EXV8 F7EXV8 PTHR12371:SF3 TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN 1 localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;protein insertion into membrane#GO:0051205 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000007439.4|UniProtKB=F7DVT3 F7DVT3 NRP1 PTHR46806:SF4 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN NEUROPILIN-1 kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714 regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;tube development#GO:0035295;plasma membrane bounded cell projection organization#GO:0120036;tissue development#GO:0009888;neural crest cell development#GO:0014032;cell migration#GO:0016477;stem cell differentiation#GO:0048863;axon development#GO:0061564;response to wounding#GO:0009611;cellular developmental process#GO:0048869;developmental process#GO:0032502;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;system development#GO:0048731;regulation of cell projection assembly#GO:0060491;cell communication#GO:0007154;regulation of cell motility#GO:2000145;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;cell projection morphogenesis#GO:0048858;animal organ development#GO:0048513;neural crest cell differentiation#GO:0014033;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;mesenchymal cell differentiation#GO:0048762;signaling#GO:0023052;cell projection organization#GO:0030030;circulatory system development#GO:0072359;cell differentiation#GO:0030154;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;blood vessel morphogenesis#GO:0048514;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;sprouting angiogenesis#GO:0002040;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon guidance#GO:0007411;positive regulation of locomotion#GO:0040017;regulation of filopodium assembly#GO:0051489;neuron projection guidance#GO:0097485;mesenchyme development#GO:0060485;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;neuron projection morphogenesis#GO:0048812;regulation of cell projection organization#GO:0031344;regulation of cell communication#GO:0010646;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cell projection organization#GO:0031346;stem cell development#GO:0048864;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;vasculogenesis#GO:0001570;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;neural crest cell migration#GO:0001755;cellular process#GO:0009987;neuron projection development#GO:0031175;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;response to stimulus#GO:0050896;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;vascular endothelial growth factor receptor signaling pathway#GO:0048010;neuron development#GO:0048666;axonogenesis#GO:0007409;angiogenesis#GO:0001525;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108 axon#GO:0030424;cell junction#GO:0030054;anchoring junction#GO:0070161;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;focal adhesion#GO:0005925;plasma membrane#GO:0005886;cell projection#GO:0042995;cell-substrate junction#GO:0030055 Axon guidance mediated by semaphorins#P00007>Neuropilin 1#P00338 MONDO|Ensembl=ENSMODG00000015921.4|UniProtKB=F6Z385 F6Z385 PTHR24019:SF11 ADIPOLIN ERYTHROFERRONE signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000008088.4|UniProtKB=F7GFW8 F7GFW8 GPAT2 PTHR12563:SF15 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 2, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 neutral lipid metabolic process#GO:0006638;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;triglyceride biosynthetic process#GO:0019432;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000008822.4|UniProtKB=F6Q994 F6Q994 FAM114A2 PTHR12842:SF3 FI01459P PROTEIN FAM114A2 MONDO|Ensembl=ENSMODG00000004237.4|UniProtKB=F6UBJ7 F6UBJ7 CDH9 PTHR24027:SF99 CADHERIN-23 CADHERIN-9 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell migration#GO:0016477;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;synaptic membrane adhesion#GO:0099560;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;synapse organization#GO:0050808;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330;cell motility#GO:0048870;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000040094.1|UniProtKB=A0A5F8H3E7 A0A5F8H3E7 PTHR26453:SF0 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13D1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000043149.1|UniProtKB=A0A5F8G6D8 A0A5F8G6D8 LOC100618281 PTHR24377:SF980 IP01015P-RELATED ZINC FINGER PROTEIN 420 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000021461.4|UniProtKB=A0A5F8GTP8 A0A5F8GTP8 DLGAP1 PTHR12353:SF7 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 1 regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177 postsynaptic specialization#GO:0099572;cell junction#GO:0030054;organelle#GO:0043226;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000015763.2|UniProtKB=A0A5F8GM65 A0A5F8GM65 PTHR21569:SF16 RIBOSOMAL PROTEIN S9 SMALL RIBOSOMAL SUBUNIT PROTEIN US9 binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;RNA binding#GO:0003723 cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000014324.3|UniProtKB=F6V599 F6V599 MZT2B PTHR28578:SF2 MITOTIC-SPINDLE ORGANIZING PROTEIN 2A-RELATED MITOTIC-SPINDLE ORGANIZING PROTEIN 2A organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000024141.2|UniProtKB=F6UJT4 F6UJT4 PTHR23176:SF104 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 27 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 MONDO|Ensembl=ENSMODG00000017762.4|UniProtKB=F7E4K5 F7E4K5 CDCA8 PTHR16040:SF6 AUSTRALIN, ISOFORM A-RELATED BOREALIN cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;chromosome localization#GO:0050000;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;mitotic metaphase chromosome alignment#GO:0007080;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;mitotic cell cycle#GO:0000278;organelle localization#GO:0051640;nuclear division#GO:0000280;localization#GO:0051179;organelle fission#GO:0048285 microtubule cytoskeleton#GO:0015630;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;intracellular organelle#GO:0043229;spindle#GO:0005819;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;spindle midzone#GO:0051233;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000003279.4|UniProtKB=F7EGI5 F7EGI5 AATF PTHR15565:SF0 AATF PROTEIN APOPTOSIS ANTAGONIZING TRANSCRIPTION FACTOR PROTEIN AATF nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467 intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000015376.5|UniProtKB=A0A5F8H540 A0A5F8H540 STRN PTHR15653:SF2 STRIATIN STRIATIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;signaling#GO:0023052;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 postsynapse#GO:0098794;cell body#GO:0044297;neuron projection#GO:0043005;protein-containing complex#GO:0032991;synapse#GO:0045202;cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000002144.3|UniProtKB=H9H5Z7 H9H5Z7 SF3B6 PTHR48526:SF2 SPLICING FACTOR 3B SUBUNIT 6 SPLICING FACTOR 3B SUBUNIT 6 MONDO|Ensembl=ENSMODG00000018541.4|UniProtKB=F7GD26 F7GD26 IL20RB PTHR20859:SF48 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-20 RECEPTOR SUBUNIT BETA cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000049662.1|UniProtKB=A0A5F8GQ73 A0A5F8GQ73 PTHR14647:SF56 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSYLCERAMIDE SULFOTRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;primary metabolic process#GO:0044238;system development#GO:0048731;anatomical structure development#GO:0048856;ceramide metabolic process#GO:0006672;glycolipid biosynthetic process#GO:0009247;glycosphingolipid biosynthetic process#GO:0006688;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;multicellular organismal process#GO:0032501;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;myelination#GO:0042552;carbohydrate derivative biosynthetic process#GO:1901137;multicellular organism development#GO:0007275;lipid metabolic process#GO:0006629;developmental process#GO:0032502;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665 transferase#PC00220 MONDO|Ensembl=ENSMODG00000024515.1|UniProtKB=F7AKM0 F7AKM0 LOC100028592 PTHR48002:SF153 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048832.1|UniProtKB=F6Z2Y8 F6Z2Y8 PTHR48168:SF1 RNA GUANINE-7 METHYLTRANSFERASE-ACTIVATING SUBUNIT-LIKE (PSEUDOGENE)-RELATED RNA GUANINE-N7 METHYLTRANSFERASE ACTIVATING SUBUNIT-RELATED molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;enzyme activator activity#GO:0008047 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000001993.4|UniProtKB=F6RHV4 F6RHV4 PTHR14166:SF6 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 2-RELATED molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;regulation of biological quality#GO:0065008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;developmental process#GO:0032502;regulation of cell migration#GO:0030334;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;regulation of locomotion#GO:0040012;nervous system development#GO:0007399;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013 cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978;neuron projection#GO:0043005;dendritic spine#GO:0043197;postsynapse#GO:0098794;cell junction#GO:0030054;dendritic tree#GO:0097447;dendrite#GO:0030425 GTPase-activating protein#PC00257;G-protein modulator#PC00022 PDGF signaling pathway#P00047>Rho#P01174 MONDO|Ensembl=ENSMODG00000017330.5|UniProtKB=F6WVU0 F6WVU0 HIVEP3 PTHR45944:SF5 SCHNURRI, ISOFORM F TRANSCRIPTION FACTOR HIVEP3 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000008349.4|UniProtKB=F7EK79 F7EK79 B4GAT1 PTHR46420:SF1 BETA-1,4-GLUCURONYLTRANSFERASE 1 BETA-1,4-GLUCURONYLTRANSFERASE 1 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220 MONDO|Ensembl=ENSMODG00000038734.1|UniProtKB=K7E5T6 K7E5T6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000015853.1|UniProtKB=F7F0D4 F7F0D4 POMC PTHR11416:SF7 PRO-OPIOMELANOCORTIN PRO-OPIOMELANOCORTIN molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;cellular pigmentation#GO:0033059;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;pigmentation#GO:0043473 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 Cortocotropin releasing factor receptor signaling pathway#P04380>ACTH#P04453;Opioid proopiomelanocortin pathway#P05917>ACTH#P06008;Cortocotropin releasing factor receptor signaling pathway#P04380>proopiomelanocortin#G04671;Cortocotropin releasing factor receptor signaling pathway#P04380>beta-endorphin#P04455;Opioid proopiomelanocortin pathway#P05917>alpha-MSH#P06007;Opioid proopiomelanocortin pathway#P05917>beta-Endorphin#P06006;Opioid proopiomelanocortin pathway#P05917>proopiomelanocortin#P06010;Cortocotropin releasing factor receptor signaling pathway#P04380>proopiomelanocortin#P04452 MONDO|Ensembl=ENSMODG00000028572.2|UniProtKB=K7E0L6 K7E0L6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000003956.4|UniProtKB=F7FYT0 F7FYT0 NOL11 PTHR15633:SF2 NUCLEOLAR PROTEIN 11 NUCLEOLAR PROTEIN 11 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000000649.4|UniProtKB=F6SUF1 F6SUF1 LRRC7 PTHR23119:SF48 DISCS LARGE LEUCINE-RICH REPEAT-CONTAINING PROTEIN 7 protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;macromolecule localization#GO:0033036;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of plasma membrane bounded cell projection organization#GO:0120035;intracellular protein localization#GO:0008104;regulation of cell projection organization#GO:0031344;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;protein localization to membrane#GO:0072657;regulation of biological process#GO:0050789;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment or maintenance of cell polarity#GO:0007163;positive regulation of neuron projection development#GO:0010976;establishment or maintenance of bipolar cell polarity#GO:0061245;positive regulation of cell projection organization#GO:0031346;cell adhesion#GO:0007155;localization within membrane#GO:0051668;positive regulation of cellular component organization#GO:0051130;receptor clustering#GO:0043113 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cell-cell junction#GO:0005911;main axon#GO:0044304;neuron projection#GO:0043005;cell junction#GO:0030054;adherens junction#GO:0005912;anchoring junction#GO:0070161;axon#GO:0030424 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000012020.4|UniProtKB=F7AM15 F7AM15 SNRPA1 PTHR10552:SF11 U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A' RNA binding#GO:0003723;snRNA binding#GO:0017069;nucleic acid binding#GO:0003676;binding#GO:0005488 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;U2 snRNP#GO:0005686;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;small nuclear ribonucleoprotein complex#GO:0030532;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000008425.4|UniProtKB=F6VDV5 F6VDV5 CYFIP2 PTHR12195:SF5 CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED CYTOPLASMIC FMR1-INTERACTING PROTEIN 2 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;apoptotic process#GO:0006915;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;regulation of protein metabolic process#GO:0051246;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;anatomical structure development#GO:0048856;system development#GO:0048731;programmed cell death#GO:0012501;cell death#GO:0008219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;axon guidance#GO:0007411;axon development#GO:0061564;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036 intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;neuron projection#GO:0043005 scaffold/adaptor protein#PC00226 Huntington disease#P00029>p53#P00797 MONDO|Ensembl=ENSMODG00000001687.4|UniProtKB=F6S7T5 F6S7T5 MRPS27 PTHR21393:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S27 SMALL RIBOSOMAL SUBUNIT PROTEIN MS27 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000006951.4|UniProtKB=F6RFH4 F6RFH4 CHRNB1 PTHR18945:SF477 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT BETA ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic cation transmembrane transporter activity#GO:0008324 regulation of biological process#GO:0050789;muscle system process#GO:0003012;skeletal muscle contraction#GO:0003009;signaling#GO:0023052;response to stimulus#GO:0050896;nervous system process#GO:0050877;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;synaptic signaling#GO:0099536;response to chemical#GO:0042221;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;striated muscle contraction#GO:0006941;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;neuromuscular process#GO:0050905;trans-synaptic signaling#GO:0099537;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;synaptic transmission, cholinergic#GO:0007271;transport#GO:0006810;muscle contraction#GO:0006936;system process#GO:0003008;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>beta#P01095 MONDO|Ensembl=ENSMODG00000007434.2|UniProtKB=A0A5F8GTX9 A0A5F8GTX9 NAA38 PTHR10701:SF5 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N N-ALPHA-ACETYLTRANSFERASE 38, NATC AUXILIARY SUBUNIT RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000024078.3|UniProtKB=F7BYB2 F7BYB2 FAM181A PTHR33766:SF1 PROTEIN FAM181B PROTEIN FAM181A MONDO|Ensembl=ENSMODG00000020264.4|UniProtKB=F7CJG1 F7CJG1 MSH3 PTHR11361:SF158 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH3 binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677 gene expression#GO:0010467;somatic recombination of immunoglobulin gene segments#GO:0016447;cellular process#GO:0009987;response to stress#GO:0006950;multicellular organism development#GO:0007275;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;production of molecular mediator of immune response#GO:0002440;response to stimulus#GO:0050896;mismatch repair#GO:0006298;immune system development#GO:0002520;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;cellular response to stress#GO:0033554;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;somatic cell DNA recombination#GO:0016444;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;multicellular organismal process#GO:0032501;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;DNA damage response#GO:0006974;DNA repair#GO:0006281;cellular response to stimulus#GO:0051716;somatic diversification of immune receptors#GO:0002200;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;system development#GO:0048731;anatomical structure development#GO:0048856;mitotic recombination#GO:0006312 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000013089.4|UniProtKB=F7EXQ5 F7EXQ5 RCAN3 PTHR10300:SF6 CALCIPRESSIN CALCIPRESSIN-3 molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000011440.4|UniProtKB=F6W1M1 F6W1M1 ANKAR PTHR46464:SF1 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN AND ARMADILLO REPEAT-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000050662.1|UniProtKB=K7E3N4 K7E3N4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000018152.4|UniProtKB=F7CWS9 F7CWS9 SPICE1 PTHR31167:SF3 SPINDLE AND CENTRIOLE ASSOCIATED PROTEIN 1 SPICE1 SPINDLE AND CENTRIOLE-ASSOCIATED PROTEIN 1 cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;regulation of microtubule-based process#GO:0032886;organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070;regulation of organelle assembly#GO:1902115;mitotic spindle assembly#GO:0090307;biological regulation#GO:0065007;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;mitotic spindle organization#GO:0007052;regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087;nuclear division#GO:0000280;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cellular process#GO:0009987;cellular component assembly#GO:0022607;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000040518.1|UniProtKB=A0A5F8GWR8 A0A5F8GWR8 CSNK2B PTHR11740:SF45 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Parkinson disease#P00049>Casein kinase II#P01236 MONDO|Ensembl=ENSMODG00000025510.2|UniProtKB=F6QY36 F6QY36 PTHR26453:SF237 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2C1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019667.4|UniProtKB=A0A5F8H0M0 A0A5F8H0M0 DAB2IP PTHR10194:SF26 RAS GTPASE-ACTIVATING PROTEINS DISABLED HOMOLOG 2-INTERACTING PROTEIN GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 MONDO|Ensembl=ENSMODG00000040645.1|UniProtKB=A0A5F8H023 A0A5F8H023 PTHR35543:SF1 PROTEIN C11ORF74 INTRAFLAGELLAR TRANSPORT-ASSOCIATED PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488 multicellular organismal reproductive process#GO:0048609;spermatogenesis#GO:0007283;developmental process#GO:0032502;sexual reproduction#GO:0019953;reproductive process#GO:0022414;fertilization#GO:0009566;male gamete generation#GO:0048232;gamete generation#GO:0007276;acrosome reaction#GO:0007340;developmental process involved in reproduction#GO:0003006;single fertilization#GO:0007338 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;9+0 non-motile cilium#GO:0097731;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025 MONDO|Ensembl=ENSMODG00000003608.4|UniProtKB=F7C6J4 F7C6J4 PLPP3 PTHR10165:SF79 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 3 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 cell adhesion#GO:0007155;cell communication#GO:0007154;dephosphorylation#GO:0016311;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;organophosphate metabolic process#GO:0019637;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 phosphatase#PC00181;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000023523.2|UniProtKB=F6Z1R2 F6Z1R2 PTHR10693:SF21 RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;binding#GO:0005488;DNA helicase activity#GO:0003678;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on DNA#GO:0140097;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724 cellular component assembly#GO:0022607;cytoplasmic stress granule assembly#GO:0034063;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925 cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytosol#GO:0005829;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000018321.3|UniProtKB=Q6YNX4 Q6YNX4 CGA PTHR11509:SF0 GLYCOPROTEIN HORMONE ALPHA CHAIN GLYCOPROTEIN HORMONES ALPHA CHAIN signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 peptide hormone#PC00179;intercellular signal molecule#PC00207 Thyrotropin-releasing hormone receptor signaling pathway#P04394>Thyrotropin#P04588;Gonadotropin-releasing hormone receptor pathway#P06664>CGA#G06886;Gonadotropin-releasing hormone receptor pathway#P06664>CGA#G06673;Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH#P04585;Thyrotropin-releasing hormone receptor signaling pathway#P04394>ProTRH (Pro Thyrotropin-releasing Hormone)#P04586 MONDO|Ensembl=ENSMODG00000003650.4|UniProtKB=F7AZW7 F7AZW7 GLRA3 PTHR18945:SF455 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-3 monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820 cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;organelle#GO:0043226;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;synaptic membrane#GO:0097060;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;cell junction#GO:0030054 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000041633.1|UniProtKB=K7E563 K7E563 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000029044.2|UniProtKB=K7E192 K7E192 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000007860.4|UniProtKB=A0A5F8GGE9 A0A5F8GGE9 GABRB2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000000623.4|UniProtKB=F6TAQ4 F6TAQ4 MMP7 PTHR10201:SF143 MATRIX METALLOPROTEINASE MATRILYSIN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 CCKR signaling map#P06959>MMP7#G06996;CCKR signaling map#P06959>MMP7#G07290;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130;Wnt signaling pathway#P00057>Wnt Target Genes#G01558 MONDO|Ensembl=ENSMODG00000007266.4|UniProtKB=A0A5F8GCK2 A0A5F8GCK2 PTHR19229:SF98 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA3 ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;lipid transport#GO:0006869;localization#GO:0051179;transport#GO:0006810;lipid localization#GO:0010876;macromolecule localization#GO:0033036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000018114.4|UniProtKB=F7F201 F7F201 SLC35A5 PTHR10231:SF90 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-SUGAR TRANSPORTER PROTEIN SLC35A5 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227 transporter#PC00227 MONDO|Ensembl=ENSMODG00000013374.4|UniProtKB=A0A5F8G1S4 A0A5F8G1S4 ARIH2 PTHR11685:SF210 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ARIH2 protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;binding#GO:0005488;acyltransferase activity#GO:0016746;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000027397.1|UniProtKB=K7E6C6 K7E6C6 TMEM229A PTHR31746:SF2 TRANSMEMBRANE PROTEIN 229 FAMILY MEMBER TRANSMEMBRANE PROTEIN 229A MONDO|Ensembl=ENSMODG00000018098.4|UniProtKB=F7FFP8 F7FFP8 USP45 PTHR21646:SF34 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 45 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of protein stability#GO:0031647;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological quality#GO:0065008;cellular response to stress#GO:0033554 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000023313.2|UniProtKB=F6RSJ9 F6RSJ9 PTHR24249:SF82 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 3-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000019748.4|UniProtKB=F6WNB3 F6WNB3 NR6A1 PTHR48092:SF18 KNIRPS-RELATED PROTEIN-RELATED NUCLEAR RECEPTOR SUBFAMILY 6 GROUP A MEMBER 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000041408.1|UniProtKB=Q2QL99 Q2QL99 CAPZA2 PTHR10653:SF2 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of actin filament depolymerization#GO:0030834;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064 cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000040984.1|UniProtKB=A0A5F8GLP3 A0A5F8GLP3 PDXP PTHR19288:SF94 4-NITROPHENYLPHOSPHATASE-RELATED CHRONOPHIN catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000014739.4|UniProtKB=F6ZC33 F6ZC33 PCDH8 PTHR24028:SF46 CADHERIN-87A PROTOCADHERIN-8 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000025577.2|UniProtKB=F6U2Q2 F6U2Q2 PTHR10510:SF5 CYTOCHROME C OXIDASE POLYPEPTIDE 7A CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;metabolic process#GO:0008152 respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 oxidoreductase#PC00176;oxidase#PC00175 MONDO|Ensembl=ENSMODG00000022671.3|UniProtKB=H9H749 H9H749 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000006872.4|UniProtKB=F6PWY1 F6PWY1 ARFGAP3 PTHR45686:SF1 ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 3 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000004068.4|UniProtKB=F6VW95 F6VW95 SAMD12 PTHR20843:SF2 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 10 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 12 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000048910.1|UniProtKB=A0A5F8GPL9 A0A5F8GPL9 PTHR48002:SF122 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4F6 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003384.4|UniProtKB=F6Z1Q5 F6Z1Q5 DNAJA1 PTHR43888:SF8 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ HOMOLOG SUBFAMILY A MEMBER 1 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671;protein binding#GO:0005515 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;response to stress#GO:0006950;macromolecule localization#GO:0033036;cellular response to heat#GO:0034605;response to heat#GO:0009408;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;localization#GO:0051179;protein refolding#GO:0042026;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;protein localization to mitochondrion#GO:0070585;cellular response to stimulus#GO:0051716;protein localization to organelle#GO:0033365;response to stimulus#GO:0050896;protein folding#GO:0006457 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000003754.4|UniProtKB=F7DV34 F7DV34 MITF PTHR45776:SF4 MIP04163P MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 cellular process#GO:0009987;developmental pigmentation#GO:0048066;melanocyte differentiation#GO:0030318;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;pigmentation#GO:0043473;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000007769.4|UniProtKB=F7AX09 F7AX09 PER1 PTHR11269:SF8 PERIOD CIRCADIAN PROTEIN PERIOD CIRCADIAN PROTEIN HOMOLOG 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription factor binding#GO:0008134;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676 response to radiation#GO:0009314;negative regulation of macromolecule metabolic process#GO:0010605;regulation of circadian rhythm#GO:0042752;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;photoperiodism#GO:0009648;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to light stimulus#GO:0009416;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;circadian regulation of gene expression#GO:0032922;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;rhythmic process#GO:0048511;circadian rhythm#GO:0007623;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 transcription cofactor#PC00217 Gonadotropin-releasing hormone receptor pathway#P06664>mPer1#G06895;Gonadotropin-releasing hormone receptor pathway#P06664>mPer1#G06681;Circadian clock system#P00015>Per#P00504;Circadian clock system#P00015>per#G01503;Circadian clock system#P00015>per#G01499 MONDO|Ensembl=ENSMODG00000013506.4|UniProtKB=F7F8B6 F7F8B6 PTHR10570:SF5 T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN / DELTA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 DELTA CHAIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;immune system process#GO:0002376;anatomical structure development#GO:0048856;cell communication#GO:0007154;mononuclear cell differentiation#GO:1903131;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;leukocyte differentiation#GO:0002521;T cell activation#GO:0042110;leukocyte activation#GO:0045321;cell development#GO:0048468;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular process#GO:0009987;signal transduction#GO:0007165;T cell differentiation#GO:0030217;biological regulation#GO:0065007;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>CD3 delta#P01326 MONDO|Ensembl=ENSMODG00000005911.4|UniProtKB=F6XCW7 F6XCW7 ILF3 PTHR45762:SF4 ZINC FINGER RNA-BINDING PROTEIN INTERLEUKIN ENHANCER-BINDING FACTOR 3 double-stranded RNA binding#GO:0003725;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000018351.3|UniProtKB=F6PQL0 F6PQL0 NRIP2 PTHR12917:SF17 ASPARTYL PROTEASE DDI-RELATED NUCLEAR RECEPTOR-INTERACTING PROTEIN 2 catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 aspartic protease#PC00053;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000043083.1|UniProtKB=A0A5F8GV96 A0A5F8GV96 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000018469.4|UniProtKB=F7CAJ0 F7CAJ0 USP18 PTHR24006:SF796 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBL CARBOXYL-TERMINAL HYDROLASE 18 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000017399.4|UniProtKB=F6SKS1 F6SKS1 MID1 PTHR24099:SF23 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE MIDLINE-1 regulation of microtubule-based process#GO:0032886;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000003339.2|UniProtKB=F7DCH6 F7DCH6 ABCF3 PTHR19211:SF117 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 3 nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;ATP binding#GO:0005524;anion binding#GO:0043168;binding#GO:0005488;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553 translation elongation factor#PC00222 MONDO|Ensembl=ENSMODG00000002324.4|UniProtKB=F6YCN9 F6YCN9 FNDC7 PTHR47135:SF1 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 7 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 7 MONDO|Ensembl=ENSMODG00000007431.4|UniProtKB=A0A5F8HBX5 A0A5F8HBX5 TMEM67 PTHR21274:SF2 MECKELIN MECKELIN cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 ciliary transition zone#GO:0035869;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995 MONDO|Ensembl=ENSMODG00000017248.4|UniProtKB=F6TKW2 F6TKW2 SIRT1 PTHR11085:SF9 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1 transcription regulator activity#GO:0140110;acyltransferase activity#GO:0016746;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;transcription corepressor activity#GO:0003714;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;NAD-dependent protein lysine deacetylase activity#GO:0034979;catalytic activity, acting on a protein#GO:0140096 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;heterochromatin formation#GO:0031507;constitutive heterochromatin formation#GO:0140719;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;response to stress#GO:0006950;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;cellular response to stress#GO:0033554;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519 heterochromatin#GO:0000792;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;nuclear inner membrane#GO:0005637;nuclear membrane#GO:0031965;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;organelle inner membrane#GO:0019866;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;organelle envelope#GO:0031967;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 p53 pathway#P00059>SIRT-1#P04632 MONDO|Ensembl=ENSMODG00000014995.4|UniProtKB=H9H6Q9 H9H6Q9 PNPLA2 PTHR12406:SF29 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 2 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;triacylglycerol lipase activity#GO:0004806;acyltransferase activity#GO:0016746;lipase activity#GO:0016298;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular component organization#GO:0016043;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;homeostatic process#GO:0042592;glycerolipid catabolic process#GO:0046503;lipid droplet organization#GO:0034389;triglyceride catabolic process#GO:0019433;organelle organization#GO:0006996;cellular process#GO:0009987;lipid catabolic process#GO:0016042;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;chemical homeostasis#GO:0048878;neutral lipid catabolic process#GO:0046461;neutral lipid metabolic process#GO:0006638;cellular component organization or biogenesis#GO:0071840;acylglycerol catabolic process#GO:0046464 intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular organelle#GO:0043229 phospholipase#PC00186 MONDO|Ensembl=ENSMODG00000020843.4|UniProtKB=A0A5F8G260 A0A5F8G260 ARHGEF9 PTHR47544:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000020557.4|UniProtKB=F7AQ10 F7AQ10 PDS5A PTHR12663:SF2 ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED SISTER CHROMATID COHESION PROTEIN PDS5 HOMOLOG A chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000003078.4|UniProtKB=F6PL88 F6PL88 SETBP1 PTHR46147:SF2 HISTONE-LYSINE N-METHYLTRANSFERASE ASH1 SET-BINDING PROTEIN histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;lysine N-methyltransferase activity#GO:0016278;histone H3K4 methyltransferase activity#GO:0042800;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000016601.4|UniProtKB=F6ZD89 F6ZD89 CTSZ PTHR12411:SF929 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN Z peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000004278.4|UniProtKB=F6TEP4 F6TEP4 RWDD3 PTHR15628:SF1 RWD DOMAIN-CONTAINING PROTEIN 3 RWD DOMAIN-CONTAINING PROTEIN 3 positive regulation of signaling#GO:0023056;positive regulation of intracellular signal transduction#GO:1902533;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;positive regulation of response to stimulus#GO:0048584;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of signal transduction#GO:0009967 MONDO|Ensembl=ENSMODG00000006857.4|UniProtKB=F6Q7G2 F6Q7G2 SCNN1G PTHR11690:SF19 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED EPITHELIAL SODIUM CHANNEL SUBUNIT GAMMA sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000006387.4|UniProtKB=A0A5F8GNY8 A0A5F8GNY8 ACBD6 PTHR24119:SF0 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6 heterocyclic compound binding#GO:1901363;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000005195.4|UniProtKB=F7DMV2 F7DMV2 PTHR15002:SF0 RIBOSOMAL BIOGENESIS PROTEIN LAS1L RIBOSOMAL BIOGENESIS PROTEIN LAS1L RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;nuclease activity#GO:0004518;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000001423.4|UniProtKB=F7BCR7 F7BCR7 DLGAP4 PTHR12353:SF19 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 4 regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 postsynapse#GO:0098794;organelle#GO:0043226;cell junction#GO:0030054;postsynaptic specialization#GO:0099572;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013295.3|UniProtKB=F6ZK55 F6ZK55 CRYGS PTHR11818:SF6 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN S structural molecule activity#GO:0005198 sensory perception#GO:0007600;nervous system process#GO:0050877;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856;sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;sensory organ development#GO:0007423;system process#GO:0003008;multicellular organism development#GO:0007275;animal organ development#GO:0048513;sensory system development#GO:0048880;multicellular organismal process#GO:0032501 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000013653.4|UniProtKB=F6UD73 F6UD73 RAB19 PTHR24073:SF362 DRAB5-RELATED RAS-RELATED PROTEIN RAB-19 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000001441.4|UniProtKB=F7BC74 F7BC74 PTHR13037:SF11 FORMIN FORMIN-1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;actin filament bundle assembly#GO:0051017;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029 endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;cytoskeleton#GO:0005856;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 MONDO|Ensembl=ENSMODG00000016400.3|UniProtKB=F7E8Y4 F7E8Y4 CYP24A1 PTHR24291:SF5 CYTOCHROME P450 FAMILY 4 1,25-DIHYDROXYVITAMIN D(3) 24-HYDROXYLASE, MITOCHONDRIAL oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;vitamin D metabolic process#GO:0042359;cellular process#GO:0009987;lipid catabolic process#GO:0016042;response to nutrient levels#GO:0031667;steroid metabolic process#GO:0008202;response to lipid#GO:0033993;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;steroid catabolic process#GO:0006706;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;response to stimulus#GO:0050896;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>24-Hydroxylase#P04608;Vitamin D metabolism and pathway#P04396>24-Hydroxylase#G04688 MONDO|Ensembl=ENSMODG00000047388.1|UniProtKB=A0A5F8GKQ7 A0A5F8GKQ7 LOC103101462 PTHR24381:SF384 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 2-LIKE DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000004145.4|UniProtKB=F6TZA3 F6TZA3 ZKSCAN1 PTHR23226:SF94 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000013311.4|UniProtKB=F6YW96 F6YW96 PTHR10728:SF39 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 GAMMA hydrolase activity, acting on ester bonds#GO:0016788;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;ion binding#GO:0043167;small molecule binding#GO:0036094;lipase activity#GO:0016298;cation binding#GO:0043169;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;A2-type glycerophospholipase activity#GO:0004623;calcium ion binding#GO:0005509;binding#GO:0005488;lipid binding#GO:0008289;metal ion binding#GO:0046872 metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;lipid metabolic process#GO:0006629;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644 nucleus#GO:0005634;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;Angiogenesis#P00005>cPLA2#P00251 MONDO|Ensembl=ENSMODG00000043469.1|UniProtKB=A0A5F8HCP7 A0A5F8HCP7 PTHR23087:SF12 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-14 chromatin binding#GO:0003682;binding#GO:0005488 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000051501.1|UniProtKB=A0A5F8GFL2 A0A5F8GFL2 GOLPH3L PTHR12704:SF4 TRANS-GOLGI PROTEIN GMX33 GOLGI PHOSPHOPROTEIN 3-LIKE binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;protein-macromolecule adaptor activity#GO:0030674;ion binding#GO:0043167;cargo adaptor activity#GO:0140312;lipid binding#GO:0008289;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;phosphatidylinositol phosphate binding#GO:1901981 vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;protein localization to cell periphery#GO:1990778;Golgi vesicle transport#GO:0048193;transport#GO:0006810;Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;cellular component organization#GO:0016043;Golgi organization#GO:0007030;localization#GO:0051179;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000005130.4|UniProtKB=F7EQM1 F7EQM1 RMI2 PTHR33962:SF1 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 2 RMI2 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 2 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;regulation of chromosome organization#GO:0033044;metabolic process#GO:0008152;DNA repair#GO:0006281;regulation of chromosome segregation#GO:0051983;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nuclear speck#GO:0016607;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604 MONDO|Ensembl=ENSMODG00000044336.1|UniProtKB=A0A5F8HJ14 A0A5F8HJ14 PTHR13144:SF0 TEX261 PROTEIN PROTEIN TEX261 cargo receptor activity#GO:0038024 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000003028.4|UniProtKB=F6Q1Y4 F6Q1Y4 IGFBPL1 PTHR14186:SF16 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN-LIKE 1 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000000439.4|UniProtKB=F6UT46 F6UT46 ANAPC10 PTHR12936:SF0 ANAPHASE-PROMOTING COMPLEX 10 ANAPHASE-PROMOTING COMPLEX SUBUNIT 10 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 mitotic cell cycle#GO:0000278;catabolic process#GO:0009056;cell cycle#GO:0007049;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234 Cell cycle#P00013>APC#P00481 MONDO|Ensembl=ENSMODG00000000824.3|UniProtKB=F6S901 F6S901 DCUN1D5 PTHR12281:SF6 RP42 RELATED DCN1-LIKE PROTEIN 5 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;binding#GO:0005488 positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;regulation of protein modification process#GO:0031399;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000020382.4|UniProtKB=F7F675 F7F675 DNAJC21 PTHR44029:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000011361.4|UniProtKB=F6T5A8 F6T5A8 IL12A PTHR48485:SF1 INTERLEUKIN-12 SUBUNIT BETA-RELATED INTERLEUKIN-12 SUBUNIT ALPHA growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 MONDO|Ensembl=ENSMODG00000008913.4|UniProtKB=F6V7A5 F6V7A5 GXYLT1 PTHR46012:SF3 IP22168P GLUCOSIDE XYLOSYLTRANSFERASE 1 UDP-glycosyltransferase activity#GO:0008194;xylosyltransferase activity#GO:0042285;glycosyltransferase activity#GO:0016757;UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 MONDO|Ensembl=ENSMODG00000011096.4|UniProtKB=F7DL52 F7DL52 MAK16 PTHR23405:SF4 MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED PROTEIN MAK16 HOMOLOG primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000009907.4|UniProtKB=F6UUW3 F6UUW3 SNTG1 PTHR10554:SF2 SYNTROPHIN GAMMA-1-SYNTROPHIN dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000042776.1|UniProtKB=A0A5F8GYZ8 A0A5F8GYZ8 PTHR10986:SF16 39S RIBOSOMAL PROTEIN L20 LARGE RIBOSOMAL SUBUNIT PROTEIN BL20M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000015479.5|UniProtKB=F6WWB5 F6WWB5 SPAST PTHR23074:SF173 AAA DOMAIN-CONTAINING SPASTIN hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a protein#GO:0140096;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853 developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;neuron projection morphogenesis#GO:0048812;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;cytoskeleton organization#GO:0007010;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;central nervous system development#GO:0007417;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000019416.4|UniProtKB=A0A5F8H354 A0A5F8H354 ARNT2 PTHR23042:SF6 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;signaling receptor complex#GO:0043235;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000041783.1|UniProtKB=A0A5F8G5X7 A0A5F8G5X7 KCNV1 PTHR11537:SF38 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY V MEMBER 1 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108 metal ion transport#GO:0030001;action potential#GO:0001508;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000003228.4|UniProtKB=F6TYQ5 F6TYQ5 TRMO PTHR12818:SF0 TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101 MONDO|Ensembl=ENSMODG00000018930.3|UniProtKB=F7GJU6 F7GJU6 SLC35B2 PTHR10778:SF13 SOLUTE CARRIER FAMILY 35 MEMBER B ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000000891.4|UniProtKB=A0A5F8GP10 A0A5F8GP10 AP5Z1 PTHR46488:SF1 AP-5 COMPLEX SUBUNIT ZETA-1 AP-5 COMPLEX SUBUNIT ZETA-1 MONDO|Ensembl=ENSMODG00000010588.3|UniProtKB=F7GHS8 F7GHS8 CCDC115 PTHR31996:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 115 VACUOLAR ATPASE ASSEMBLY PROTEIN VMA22 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;biological regulation#GO:0065007;homeostatic process#GO:0042592;regulation of pH#GO:0006885;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;regulation of intracellular pH#GO:0051453;vacuolar acidification#GO:0007035;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;cytoplasm#GO:0005737;vacuole#GO:0005773;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;endoplasmic reticulum#GO:0005783;proton-transporting two-sector ATPase complex#GO:0016469 MONDO|Ensembl=ENSMODG00000043543.1|UniProtKB=A0A5F8G663 A0A5F8G663 PTHR10579:SF52 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000004003.2|UniProtKB=A0A5F8G2U8 A0A5F8G2U8 PTHR10744:SF9 40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US17 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000028052.2|UniProtKB=K7E285 K7E285 PTHR46890:SF56 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED OS06G0484800 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001323.3|UniProtKB=F7BDN7 F7BDN7 PTHR24070:SF395 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-1A hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular response to nitrogen compound#GO:1901699;intracellular signal transduction#GO:0035556;regulation of exocytosis#GO:0017157;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;regulation of secretion#GO:0051046;cellular response to stimulus#GO:0051716;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;regulation of neurotransmitter transport#GO:0051588;cellular response to chemical stimulus#GO:0070887;regulation of secretion by cell#GO:1903530;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;negative regulation of biological process#GO:0048519;regulation of synaptic vesicle exocytosis#GO:2000300;signaling#GO:0023052;regulation of neurotransmitter secretion#GO:0046928;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 MONDO|Ensembl=ENSMODG00000001199.5|UniProtKB=F7GH79 F7GH79 PTHR24026:SF142 FAT ATYPICAL CADHERIN-RELATED PROTOCADHERIN-23 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 anchoring junction#GO:0070161;adherens junction#GO:0005912;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell-cell junction#GO:0005911 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000014068.4|UniProtKB=F6TSV4 F6TSV4 CNOT4 PTHR12603:SF0 CCR4-NOT TRANSCRIPTION COMPLEX RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4 ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;protein metabolic process#GO:0019538;regulation of RNA metabolic process#GO:0051252;RNA decapping#GO:0110154;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;modification-dependent protein catabolic process#GO:0019941;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;modification-dependent macromolecule catabolic process#GO:0043632;RNA catabolic process#GO:0006401;protein catabolic process#GO:0030163;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;CCR4-NOT complex#GO:0030014 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000039032.1|UniProtKB=A0A5F8HF24 A0A5F8HF24 MODO-UM PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN protein binding#GO:0005515;antigen binding#GO:0003823;peptide binding#GO:0042277;signaling receptor binding#GO:0005102;binding#GO:0005488 positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;immune system process#GO:0002376;regulation of lymphocyte mediated immunity#GO:0002706;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 MONDO|Ensembl=ENSMODG00000004294.4|UniProtKB=F6SXV6 F6SXV6 MOB3B PTHR22599:SF22 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 3B kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000006424.3|UniProtKB=F7EZJ9 F7EZJ9 PYGB PTHR11468:SF29 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE, BRAIN FORM hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 cellular process#GO:0009987;glycogen catabolic process#GO:0005980;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;generation of precursor metabolites and energy#GO:0006091;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;glucan catabolic process#GO:0009251;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;catabolic process#GO:0009056;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;carbohydrate catabolic process#GO:0016052;energy reserve metabolic process#GO:0006112 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 glycosyltransferase#PC00111;transferase#PC00220 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b#P00717;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase a#P00718 MONDO|Ensembl=ENSMODG00000045689.1|UniProtKB=F7B4S8 F7B4S8 LOC100022227 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009353.4|UniProtKB=A0A5F8GD02 A0A5F8GD02 B3GLCT PTHR10811:SF110 FRINGE-RELATED BETA-1,3-GLUCOSYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000004773.3|UniProtKB=F6WKU9 F6WKU9 MEAK7 PTHR23354:SF131 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED MTOR-ASSOCIATED PROTEIN MEAK7 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;TOR signaling#GO:0031929;response to stress#GO:0006950;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to oxidative stress#GO:0006979;intracellular signal transduction#GO:0035556 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000021534.4|UniProtKB=A0A5F8HEV0 A0A5F8HEV0 SYMPK PTHR15245:SF20 SYMPLEKIN-RELATED SYMPLEKIN intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849 MONDO|Ensembl=ENSMODG00000008382.4|UniProtKB=F7CDR6 F7CDR6 OPRM1 PTHR24229:SF7 NEUROPEPTIDES RECEPTOR MU-TYPE OPIOID RECEPTOR G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;binding#GO:0005488;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide binding#GO:0042923;peptide binding#GO:0042277 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;sensory perception of pain#GO:0019233;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 G-protein coupled receptor#PC00021 Opioid proopiomelanocortin pathway#P05917>Mu or Delta receptor#P06004;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Enkephalin release#P05913>GPCR (s)#P05975;Opioid proenkephalin pathway#P05915>Mu or Delta receptor#P05985;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 MONDO|Ensembl=ENSMODG00000013766.3|UniProtKB=F6UB55 F6UB55 RPL10A PTHR23105:SF101 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000011140.4|UniProtKB=F7BA83 F7BA83 RCBTB2 PTHR22870:SF220 REGULATOR OF CHROMOSOME CONDENSATION RCC1 AND BTB DOMAIN-CONTAINING PROTEIN 2 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000009777.4|UniProtKB=F6TF58 F6TF58 FRMD8 PTHR13283:SF10 KREV INTERACTION TRAPPED 1-RELATED FERM DOMAIN-CONTAINING PROTEIN 8 negative regulation of cell communication#GO:0010648;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical Wnt signaling pathway#GO:0060828 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000015181.4|UniProtKB=F7BWD9 F7BWD9 DHX8 PTHR18934:SF277 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX8 catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000003934.4|UniProtKB=F7GIS6 F7GIS6 TRIM7 PTHR24103:SF700 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM7 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000013319.4|UniProtKB=F7GJG6 F7GJG6 MOK PTHR24055:SF533 MITOGEN-ACTIVATED PROTEIN KINASE MAPK_MAK_MRK OVERLAPPING KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000012028.3|UniProtKB=F7ALY9 F7ALY9 ANAPC5 PTHR12830:SF9 ANAPHASE-PROMOTING COMPLEX SUBUNIT 5 ANAPHASE-PROMOTING COMPLEX SUBUNIT 5 regulation of mitotic metaphase/anaphase transition#GO:0030071;post-translational protein modification#GO:0043687;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;regulation of mitotic sister chromatid separation#GO:0010965;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of mitotic cell cycle#GO:0045931;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cell cycle phase transition#GO:1901987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of chromosome separation#GO:1905818;proteasomal protein catabolic process#GO:0010498;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;protein ubiquitination#GO:0016567;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of chromosome segregation#GO:0051983;positive regulation of mitotic nuclear division#GO:0045840;regulation of cellular component organization#GO:0051128;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;protein K11-linked ubiquitination#GO:0070979;regulation of organelle organization#GO:0033043;protein modification by small protein conjugation#GO:0032446;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;positive regulation of organelle organization#GO:0010638;regulation of mitotic cell cycle phase transition#GO:1901990;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;positive regulation of cellular component organization#GO:0051130 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461 MONDO|Ensembl=ENSMODG00000042136.1|UniProtKB=A0A5F8G248 A0A5F8G248 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018869.3|UniProtKB=F7DAQ6 F7DAQ6 SELENBP1 PTHR23300:SF0 METHANETHIOL OXIDASE METHANETHIOL OXIDASE defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000051389.1|UniProtKB=A0A5F8GTU0 A0A5F8GTU0 PTHR48018:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038728.1|UniProtKB=A0A5F8GVZ2 A0A5F8GVZ2 B4GALT6 PTHR19300:SF47 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 6 galactosyltransferase activity#GO:0008378;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000000213.4|UniProtKB=F6SZN4 F6SZN4 CARD11 PTHR14559:SF4 CASPASE RECRUITMENT DOMAIN FAMILY CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 11 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of immune response#GO:0050778;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000024215.2|UniProtKB=F6WEZ0 F6WEZ0 PTHR10903:SF199 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000001481.4|UniProtKB=F7FHX9 F7FHX9 SLAIN1 PTHR22406:SF2 NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM SLAIN MOTIF-CONTAINING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;regulation of microtubule polymerization#GO:0031113;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;microtubule nucleation#GO:0007020;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cytoplasmic microtubule organization#GO:0031122;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule polymerization#GO:0046785;microtubule polymerization or depolymerization#GO:0031109;positive regulation of cellular process#GO:0048522;positive regulation of protein polymerization#GO:0032273;biological regulation#GO:0065007;regulation of microtubule-based process#GO:0032886;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493 supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;microtubule end#GO:1990752;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000048336.1|UniProtKB=A0A5F8GL50 A0A5F8GL50 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000027990.2|UniProtKB=K7DZ95 K7DZ95 PTHR10424:SF72 VIRAL ENVELOPE PROTEIN BC035947 PROTEIN-RELATED animal gross anatomical part developmental process#GO:0160108;cell-cell fusion#GO:0140253;developmental process#GO:0032502;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;syncytium formation by cell-cell fusion#GO:0000768;striated muscle cell differentiation#GO:0051146;myoblast fusion#GO:0007520;cellular process#GO:0009987;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;cell differentiation#GO:0030154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000015930.4|UniProtKB=F7G1Y5 F7G1Y5 PTHR46299:SF1 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B2-RELATED VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B1 MONDO|Ensembl=ENSMODG00000037716.1|UniProtKB=A0A5F8GIJ2 A0A5F8GIJ2 PTHR13809:SF6 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-10 molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562 heterotrimeric G-protein#PC00117 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Enkephalin release#P05913>G-Protein (s)#P05977;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (i)#P05974;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;GABA-B receptor II signaling#P05731>Ggamma#P05754;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Wnt signaling pathway#P00057>Ggamma#P01465;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002 MONDO|Ensembl=ENSMODG00000007874.5|UniProtKB=F7EB87 F7EB87 MCMDC2 PTHR11630:SF75 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER MINICHROMOSOME MAINTENANCE DOMAIN-CONTAINING PROTEIN 2 catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094 DNA strand elongation involved in DNA replication#GO:0006271;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;mitotic cell cycle process#GO:1903047;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA replication initiation#GO:0006270;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA repair#GO:0006281;cell cycle DNA replication#GO:0044786;metabolic process#GO:0008152;nuclear DNA replication#GO:0033260;DNA metabolic process#GO:0006259;mitotic DNA replication#GO:1902969 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;MCM complex#GO:0042555;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000015053.3|UniProtKB=F7FUV1 F7FUV1 TPRG1 PTHR31108:SF6 TUMOR PROTEIN P63-REGULATED GENE 1-LIKE PROTEIN TUMOR PROTEIN P63-REGULATED GENE 1 PROTEIN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000039230.1|UniProtKB=A0A5F8H9H9 A0A5F8H9H9 PTHR10574:SF197 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-1 neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;cell adhesion#GO:0007155;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;substrate adhesion-dependent cell spreading#GO:0034446;neuron differentiation#GO:0030182;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;cellular process#GO:0009987;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;cell-substrate adhesion#GO:0031589;external encapsulating structure organization#GO:0045229;system development#GO:0048731;cell motility#GO:0048870;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell migration#GO:0016477;extracellular matrix assembly#GO:0085029;multicellular organismal process#GO:0032501;tissue development#GO:0009888;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000001349.4|UniProtKB=F7FW97 F7FW97 UCK2 PTHR10285:SF131 URIDINE KINASE URIDINE-CYTIDINE KINASE 2 nucleoside kinase activity#GO:0019206;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137;nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149 MONDO|Ensembl=ENSMODG00000041607.1|UniProtKB=A0A5F8HHN2 A0A5F8HHN2 PTHR10177:SF444 CYCLINS CYCLIN-A2 protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049 intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;transferase complex#GO:1990234;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin A#P04666 MONDO|Ensembl=ENSMODG00000005193.4|UniProtKB=F7DMZ8 F7DMZ8 MAN1A2 PTHR11742:SF40 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IB catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896 membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000015205.3|UniProtKB=F7B9Z4 F7B9Z4 DMAC1 PTHR36469:SF1 DISTAL MEMBRANE-ARM ASSEMBLY COMPLEX PROTEIN 1 DISTAL MEMBRANE-ARM ASSEMBLY COMPLEX PROTEIN 1 mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000016965.3|UniProtKB=F6V4U5 F6V4U5 PTHR22802:SF14 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER K signaling receptor activity#GO:0038023;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;binding#GO:0005488 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000027989.2|UniProtKB=K7E4P0 K7E4P0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000018825.3|UniProtKB=F6YYM6 F6YYM6 CERS2 PTHR12560:SF7 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 2 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;ceramide metabolic process#GO:0006672;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000000923.4|UniProtKB=F7F853 F7F853 R3HDM1 PTHR15672:SF12 CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN R3H DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000042812.1|UniProtKB=A0A5F8GJU1 A0A5F8GJU1 PTHR10340:SF25 SPHINGOMYELIN PHOSPHODIESTERASE ACID SPHINGOMYELINASE-LIKE PHOSPHODIESTERASE 3B hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000010041.4|UniProtKB=F6TTQ7 F6TTQ7 STK32A PTHR24356:SF143 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 32A protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000019525.4|UniProtKB=A0A5F8H086 A0A5F8H086 SETD9 PTHR33524:SF2 C5ORF35 SET DOMAIN-CONTAINING PROTEIN 9 MONDO|Ensembl=ENSMODG00000040050.1|UniProtKB=F7ASG2 F7ASG2 LOC100617842 PTHR26453:SF237 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2C1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000028224.2|UniProtKB=K7DZS8 K7DZS8 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000004189.2|UniProtKB=F6Y9W8 F6Y9W8 MVD PTHR10977:SF3 DIPHOSPHOMEVALONATE DECARBOXYLASE DIPHOSPHOMEVALONATE DECARBOXYLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;isoprenoid metabolic process#GO:0006720;organophosphate biosynthetic process#GO:0090407;isoprenoid biosynthetic process#GO:0008299;acetyl-CoA metabolic process#GO:0006084;phospholipid metabolic process#GO:0006644;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;phospholipid biosynthetic process#GO:0008654;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;lyase#PC00144 Cholesterol biosynthesis#P00014>Diphosphomevalonate decarboxylase#P00496 MONDO|Ensembl=ENSMODG00000002560.4|UniProtKB=F7GFC2 F7GFC2 TADA2A PTHR12374:SF85 TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED TRANSCRIPTIONAL ADAPTER 2-ALPHA transcription coregulator activity#GO:0003712;binding#GO:0005488;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;SAGA-type complex#GO:0070461;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000016185.3|UniProtKB=F7G8L4 F7G8L4 PTHR35268:SF1 PROTEIN CCSMST1 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 4 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740 MONDO|Ensembl=ENSMODG00000013137.4|UniProtKB=F7AZF8 F7AZF8 LOC103099763 PTHR14327:SF2 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT GAMMA CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT GAMMA-LIKE ISOFORM X1 cilium#GO:0005929;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000008015.4|UniProtKB=F7CL89 F7CL89 TTC1 PTHR46014:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 1 TETRATRICOPEPTIDE REPEAT PROTEIN 1 MONDO|Ensembl=ENSMODG00000011368.2|UniProtKB=F6SPX9 F6SPX9 OR51I1 PTHR26450:SF66 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51I1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009367.3|UniProtKB=A0A5F8HAE2 A0A5F8HAE2 LYPLA1 PTHR10655:SF22 LYSOPHOSPHOLIPASE-RELATED ACYL-PROTEIN THIOESTERASE 1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;palmitoyl hydrolase activity#GO:0098599;hydrolase activity#GO:0016787;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;thiolester hydrolase activity#GO:0016790 negative regulation of cellular process#GO:0048523;regulation of establishment of protein localization#GO:0070201;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;regulation of transport#GO:0051049;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;negative regulation of biological process#GO:0048519;negative regulation of protein transport#GO:0051224;biological regulation#GO:0065007;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phospholipase#PC00186;lipase#PC00143 MONDO|Ensembl=ENSMODG00000048699.1|UniProtKB=A0A5F8H579 A0A5F8H579 NANOS2 PTHR12887:SF10 NANOS PROTEIN NANOS HOMOLOG 2 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;reproductive process#GO:0022414;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;oogenesis#GO:0048477;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;gamete generation#GO:0007276;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;negative regulation of metabolic process#GO:0009892;negative regulation of translation#GO:0017148 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000015406.4|UniProtKB=F6ZWA9 F6ZWA9 SLC13A1 PTHR10283:SF65 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;cellular process#GO:0009987;sodium ion transport#GO:0006814;metal ion transport#GO:0030001 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000013649.5|UniProtKB=F6UD96 F6UD96 FCGRT PTHR16675:SF3 MHC CLASS I-RELATED IGG RECEPTOR FCRN LARGE SUBUNIT P51 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000019229.4|UniProtKB=F7A2R7 F7A2R7 HERC3 PTHR45622:SF18 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC3-RELATED catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000011281.4|UniProtKB=F6WZP0 F6WZP0 WDR44 PTHR14221:SF72 WD REPEAT DOMAIN 44 WD REPEAT-CONTAINING PROTEIN 44 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794 MONDO|Ensembl=ENSMODG00000021584.1|UniProtKB=Q65CI4 Q65CI4 MT-ND4 PTHR43507:SF20 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4 oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;NADH dehydrogenase activity#GO:0003954;binding#GO:0005488;small molecule binding#GO:0036094;catalytic activity#GO:0003824 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;energy derivation by oxidation of organic compounds#GO:0015980;transmembrane transport#GO:0055085;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;monoatomic ion transport#GO:0006811;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;transport#GO:0006810 respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000018024.4|UniProtKB=K7E2Y8 K7E2Y8 RTN4IP1 PTHR11695:SF652 ALCOHOL DEHYDROGENASE RELATED NAD(P)H OXIDOREDUCTASE RTN4IP1, MITOCHONDRIAL NADH dehydrogenase activity#GO:0003954;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;oxidoreductase activity, acting on NAD(P)H#GO:0016651;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;oxidoreductase activity#GO:0016491 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ketone metabolic process#GO:0042180;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000014871.3|UniProtKB=A0A5F8G5H5 A0A5F8G5H5 PTHR12162:SF0 NIBRIN-RELATED NIBRIN binding#GO:0005488;nucleic acid binding#GO:0003676;damaged DNA binding#GO:0003684;DNA binding#GO:0003677 mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;double-strand break repair#GO:0006302;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000010987.3|UniProtKB=F7APF5 F7APF5 TMC2 PTHR23302:SF17 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 2 transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267 system process#GO:0003008;response to external stimulus#GO:0009605;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;detection of mechanical stimulus#GO:0050982;multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;response to stimulus#GO:0050896;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000037117.1|UniProtKB=A0A5F8GRF1 A0A5F8GRF1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000012766.4|UniProtKB=K7DZ75 K7DZ75 SURF2 PTHR34348:SF1 SURFEIT LOCUS PROTEIN 2 SURFEIT LOCUS PROTEIN 2 MONDO|Ensembl=ENSMODG00000047798.1|UniProtKB=A0A5F8GJP7 A0A5F8GJP7 monDomV1R1252 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003647.6|UniProtKB=A0A5F8HCR8 A0A5F8HCR8 L3MBTL1 PTHR12247:SF69 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000029307.2|UniProtKB=A0A5F8G8U1 A0A5F8G8U1 PCDHAC2 PTHR24028:SF119 CADHERIN-87A PROTOCADHERIN ALPHA-C2 cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000042494.1|UniProtKB=A0A5F8H883 A0A5F8H883 PTHR17453:SF0 SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein targeting#GO:0006605;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein targeting to membrane#GO:0006612;protein-containing complex organization#GO:0043933;protein targeting to ER#GO:0045047;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;establishment of protein localization to endoplasmic reticulum#GO:0072599;cellular component assembly#GO:0022607 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000014145.4|UniProtKB=F7GKR2 F7GKR2 GINS3 PTHR22768:SF0 DNA REPLICATION COMPLEX GINS PROTEIN PSF3 DNA REPLICATION COMPLEX GINS PROTEIN PSF3 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170 DNA replication preinitiation complex#GO:0031261;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;GINS complex#GO:0000811;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000005782.4|UniProtKB=F6WY68 F6WY68 COBLL1 PTHR21557:SF2 CORDON-BLEU CORDON-BLEU PROTEIN-LIKE 1 MONDO|Ensembl=ENSMODG00000013909.4|UniProtKB=F6VBN5 F6VBN5 LOC130453672 PTHR18884:SF54 SEPTIN SEPTIN-8 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cellular process#GO:0009987;cell cycle process#GO:0022402;cell division#GO:0051301;macromolecule localization#GO:0033036;cell cycle#GO:0007049;intracellular protein localization#GO:0008104;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinesis#GO:0000910 cell cortex#GO:0005938;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000006886.3|UniProtKB=A0A5F8GSF0 A0A5F8GSF0 PTHR12042:SF17 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;liposaccharide metabolic process#GO:1903509;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000038083.1|UniProtKB=A0A5F8H8J0 A0A5F8H8J0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000040125.1|UniProtKB=A0A5F8GWK3 A0A5F8GWK3 PTHR12974:SF30 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5D adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891 MONDO|Ensembl=ENSMODG00000006686.4|UniProtKB=F7FFX8 F7FFX8 LOC100024487 PTHR10824:SF17 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COENZYME A THIOESTERASE 6 hydrolase activity#GO:0016787;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;acyl-CoA hydrolase activity#GO:0016289;deacylase activity#GO:0160215 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;nucleobase-containing compound metabolic process#GO:0006139;long-chain fatty acid metabolic process#GO:0001676;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;nucleoside phosphate metabolic process#GO:0006753;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 esterase#PC00097 MONDO|Ensembl=ENSMODG00000049237.1|UniProtKB=A0A5F8GB64 A0A5F8GB64 LOC100023288 PTHR48018:SF28 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8K3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000020204.4|UniProtKB=A0A5F8GG36 A0A5F8GG36 STX3 PTHR19957:SF34 SYNTAXIN SYNTAXIN-3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 secretion by cell#GO:0032940;regulation of biological quality#GO:0065008;protein transport#GO:0015031;cellular localization#GO:0051641;export from cell#GO:0140352;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;exocytosis#GO:0006887;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;vesicle organization#GO:0016050;protein localization to synapse#GO:0035418;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;protein localization to cell periphery#GO:1990778;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;localization#GO:0051179;secretion#GO:0046903;localization within membrane#GO:0051668;protein localization to cell junction#GO:1902414;vesicle fusion#GO:0006906;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;transport#GO:0006810;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular transport#GO:0046907;membrane organization#GO:0061024;biological regulation#GO:0065007;membrane fusion#GO:0061025;macromolecule localization#GO:0033036 cytoplasm#GO:0005737;plasma membrane#GO:0005886;SNARE complex#GO:0031201;synapse#GO:0045202;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;postsynapse#GO:0098794;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 SNARE protein#PC00034 5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005 MONDO|Ensembl=ENSMODG00000017900.5|UniProtKB=A0A5F8GM20 A0A5F8GM20 ZNF106 PTHR14435:SF2 ZINC FINGER PROTEIN 106 ZINC FINGER PROTEIN 106 MONDO|Ensembl=ENSMODG00000051572.1|UniProtKB=A0A5F8GP67 A0A5F8GP67 PTHR48026:SF28 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A0,-LIKE binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000041108.1|UniProtKB=A0A5F8HCC4 A0A5F8HCC4 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000020358.4|UniProtKB=F7FK22 F7FK22 CYB561A3 PTHR10106:SF38 CYTOCHROME B561-RELATED LYSOSOMAL MEMBRANE ASCORBATE-DEPENDENT FERRIREDUCTASE CYB561A3 active transmembrane transporter activity#GO:0022804;oxidoreductase activity, acting on metal ions#GO:0016722;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity#GO:0016491;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824 homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;carbohydrate homeostasis#GO:0033500;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000000120.3|UniProtKB=F6YBS6 F6YBS6 PTHR24241:SF171 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR QRFP-LIKE PEPTIDE RECEPTOR G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 neuropeptide signaling pathway#GO:0007218;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000015988.4|UniProtKB=F7EZC3 F7EZC3 EIF4G3 PTHR23253:SF23 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 3 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;translation factor activity#GO:0180051;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743 translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000003419.3|UniProtKB=F7GKN3 F7GKN3 PTHR34917:SF1 RBPJ-INTERACTING AND TUBULIN-ASSOCIATED PROTEIN 1 RBPJ-INTERACTING AND TUBULIN-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;nucleocytoplasmic transport#GO:0006913;negative regulation of signaling#GO:0023057;nuclear transport#GO:0051169;nuclear export#GO:0051168;negative regulation of cell communication#GO:0010648;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;negative regulation of Notch signaling pathway#GO:0045746;regulation of response to stimulus#GO:0048583;transport#GO:0006810;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000014161.5|UniProtKB=F6UN22 F6UN22 WDR62 PTHR45589:SF3 WD REPEAT DOMAIN 62, ISOFORM G WD REPEAT-CONTAINING PROTEIN 62 biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789 spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000041697.1|UniProtKB=F7EB70 F7EB70 VN2R527 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000009240.4|UniProtKB=F7EDQ2 F7EDQ2 ESR2 PTHR48092:SF12 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN RECEPTOR BETA transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837 cellular response to steroid hormone stimulus#GO:0071383;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;estrogen receptor signaling pathway#GO:0030520;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to steroid hormone#GO:0048545;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;steroid hormone receptor signaling pathway#GO:0043401;intracellular receptor signaling pathway#GO:0030522;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000043390.1|UniProtKB=A0A5F8HFM5 A0A5F8HFM5 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000038779.1|UniProtKB=A0A5F8HLV3 A0A5F8HLV3 FAM131C PTHR15736:SF2 PROTEIN FAM131B-RELATED PROTEIN FAM131C MONDO|Ensembl=ENSMODG00000014525.4|UniProtKB=F7ERM6 F7ERM6 EAPP PTHR15967:SF1 E2F-ASSOCIATED PHOSPHOPROTEIN E2F-ASSOCIATED PHOSPHOPROTEIN transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cell population proliferation#GO:0042127;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000028694.2|UniProtKB=K7E023 K7E023 PPDPFL PTHR14572:SF1 PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR-LIKE PROTEIN MONDO|Ensembl=ENSMODG00000010070.3|UniProtKB=F6XNB9 F6XNB9 MRPL40 PTHR13359:SF2 39S RIBOSOMAL PROTEIN L40, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML40 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000023065.2|UniProtKB=A0A5F8G558 A0A5F8G558 ZNF319 PTHR24376:SF95 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 319 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000024440.2|UniProtKB=F7DJJ2 F7DJJ2 CHRM2 PTHR24247:SF207 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M2 neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;acetylcholine receptor activity#GO:0015464;postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089 synaptic signaling#GO:0099536;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;regulation of system process#GO:0044057;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of smooth muscle contraction#GO:0006940;regulation of muscle system process#GO:0090257;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of muscle contraction#GO:0006937;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;trans-synaptic signaling#GO:0099537;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698 dendrite#GO:0030425;dendritic tree#GO:0097447;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>mAChR2/4#P01077;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 MONDO|Ensembl=ENSMODG00000010152.4|UniProtKB=A0A5F8H7M7 A0A5F8H7M7 MRC2 PTHR22803:SF69 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED C-TYPE MANNOSE RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000003105.3|UniProtKB=F6S3F6 F6S3F6 VPS4A PTHR23074:SF83 AAA DOMAIN-CONTAINING VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;vacuole organization#GO:0007033;protein metabolic process#GO:0019538;cellular localization#GO:0051641;localization#GO:0051179;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;transport#GO:0006810;intracellular transport#GO:0046907;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;endosomal transport#GO:0016197;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000044877.1|UniProtKB=A0A5F8HFL4 A0A5F8HFL4 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000012018.4|UniProtKB=A0A5F8GI94 A0A5F8GI94 NFATC1 PTHR12533:SF5 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;regulation of biological process#GO:0050789;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;calcineurin-NFAT signaling cascade#GO:0033173;calcineurin-mediated signaling#GO:0097720;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;calcium-mediated signaling#GO:0019722;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 immunoglobulin fold transcription factor#PC00251;gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252 Wnt signaling pathway#P00057>NFAT#P01452;T cell activation#P00053>NFAT#P01294;B cell activation#P00010>NFAT#P00367;Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851 MONDO|Ensembl=ENSMODG00000018204.5|UniProtKB=F6PGX6 F6PGX6 GRIN2B PTHR18966:SF382 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2B amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;voltage-gated monoatomic ion channel activity#GO:0005244;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;molecular transducer activity#GO:0060089;channel activity#GO:0015267 signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;regulation of trans-synaptic signaling#GO:0099177;cell surface receptor signaling pathway#GO:0007166;regulation of membrane potential#GO:0042391;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;nervous system process#GO:0050877;positive regulation of synaptic transmission#GO:0050806;regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of synaptic plasticity#GO:0048167;system process#GO:0003008;regulation of postsynaptic membrane potential#GO:0060078;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;modulation of chemical synaptic transmission#GO:0050804;chemical synaptic transmission, postsynaptic#GO:0099565;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>NR2B#P01007;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024 MONDO|Ensembl=ENSMODG00000021427.4|UniProtKB=F7CBE8 F7CBE8 PRELID3A PTHR11158:SF23 MSF1/PX19 RELATED PRELI DOMAIN CONTAINING PROTEIN 3A molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013 establishment of localization#GO:0051234;localization#GO:0051179;lipid localization#GO:0010876;transport#GO:0006810;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;phospholipid transport#GO:0015914;macromolecule localization#GO:0033036 mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000017317.4|UniProtKB=F6XCK8 F6XCK8 C8G PTHR47304:SF1 COMPLEMENT COMPONENT C8 GAMMA CHAIN COMPLEMENT COMPONENT C8 GAMMA CHAIN regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of biological process#GO:0050789;immune system process#GO:0002376;regulation of immune response#GO:0050776;defense response to other organism#GO:0098542;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;immune response#GO:0006955;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;activation of immune response#GO:0002253;complement activation#GO:0006956;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;humoral immune response#GO:0006959;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;positive regulation of immune response#GO:0050778 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 complement component#PC00078 MONDO|Ensembl=ENSMODG00000019642.4|UniProtKB=F6UB08 F6UB08 ADAMTS6 PTHR13723:SF27 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 6 metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000011414.3|UniProtKB=F6RL31 F6RL31 PTHR16675:SF67 MHC CLASS I-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000006234.5|UniProtKB=F7FS46 F7FS46 NEURL1B PTHR12429:SF10 NEURALIZED E3 UBIQUITIN-PROTEIN LIGASE NEURL1B acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 transport#GO:0006810;regulation of response to stimulus#GO:0048583;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;import into cell#GO:0098657;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;protein transport#GO:0015031;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000029476.2|UniProtKB=K7DYV8 K7DYV8 PTHR41694:SF8 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 11 POL PROTEIN-LIKE RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000019483.4|UniProtKB=F6WAB4 F6WAB4 PTHR11949:SF24 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 9 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000044206.1|UniProtKB=A0A5F8GK74 A0A5F8GK74 PTHR15527:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM6 HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM6 HOMOLOG outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial outer membrane translocase complex#GO:0005742;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000008491.5|UniProtKB=F6VDX1 F6VDX1 AXL PTHR24416:SF323 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR UFO transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773 multicellular organism development#GO:0007275;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;nervous system development#GO:0007399;lymphocyte activation#GO:0046649;regulation of signaling#GO:0023051;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;wound healing#GO:0042060;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cell development#GO:0048468;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;endocytosis#GO:0006897;transport#GO:0006810;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;blood coagulation#GO:0007596;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;hemostasis#GO:0007599;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of apoptotic process#GO:0042981;natural killer cell activation#GO:0030101;cell surface receptor signaling pathway#GO:0007166;import into cell#GO:0098657;coagulation#GO:0050817;response to stress#GO:0006950;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;mononuclear cell differentiation#GO:1903131;regulation of programmed cell death#GO:0043067;leukocyte differentiation#GO:0002521;signaling#GO:0023052;cell differentiation#GO:0030154;regulation of body fluid levels#GO:0050878;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;phagocytosis#GO:0006909;platelet activation#GO:0030168;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;response to wounding#GO:0009611;hemopoiesis#GO:0030097;regulation of signal transduction#GO:0009966;negative regulation of apoptotic process#GO:0043066;cell migration#GO:0016477;lymphocyte differentiation#GO:0030098;cell activation#GO:0001775;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;system development#GO:0048731;cell communication#GO:0007154;localization#GO:0051179;enzyme-linked receptor protein signaling pathway#GO:0007167;leukocyte activation#GO:0045321;positive regulation of cell communication#GO:0010647 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014681.4|UniProtKB=F7DNP7 F7DNP7 JUP PTHR45976:SF3 ARMADILLO SEGMENT POLARITY PROTEIN JUNCTION PLAKOGLOBIN protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713;protein phosphatase binding#GO:0019903;transcription coregulator activity#GO:0003712;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;cell adhesion molecule binding#GO:0050839 regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;cell adhesion#GO:0007155;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;canonical Wnt signaling pathway#GO:0060070;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;nucleus#GO:0005634;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898 Alzheimer disease-presenilin pathway#P00004>gammacatenin#P00153 MONDO|Ensembl=ENSMODG00000005655.4|UniProtKB=A0A5F8GHP6 A0A5F8GHP6 GAK PTHR23172:SF34 AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED CYCLIN-G-ASSOCIATED KINASE protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component disassembly#GO:0022411;receptor-mediated endocytosis#GO:0006898;protein-containing complex organization#GO:0043933;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000023134.1|UniProtKB=F7DVA1 F7DVA1 PTHR20835:SF0 E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED E3 UBIQUITIN-PROTEIN LIGASE PPP1R11 phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase binding#GO:0019903;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000001518.3|UniProtKB=F7F467 F7F467 GLP2R PTHR45620:SF23 PDF RECEPTOR-LIKE PROTEIN-RELATED GLUCAGON-LIKE PEPTIDE 2 RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011885.4|UniProtKB=F7G2K7 F7G2K7 TJP1 PTHR13865:SF25 TIGHT JUNCTION PROTEIN TIGHT JUNCTION PROTEIN 1 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 tissue homeostasis#GO:0001894;regulation of biological quality#GO:0065008;localization#GO:0051179;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;protein localization to cell junction#GO:1902414;circulatory system process#GO:0003013;animal gross anatomical part developmental process#GO:0160108;homeostatic process#GO:0042592;cell development#GO:0048468;cell differentiation#GO:0030154;cell junction organization#GO:0034330;cellular component organization#GO:0016043;system process#GO:0003008;intracellular protein localization#GO:0008104;multicellular organismal-level homeostasis#GO:0048871;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;endothelial cell differentiation#GO:0045446;biological regulation#GO:0065007;epithelium development#GO:0060429;blood circulation#GO:0008015;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;cellular process#GO:0009987;macromolecule localization#GO:0033036;cell-cell adhesion#GO:0098609 apical junction complex#GO:0043296;anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165 cell junction protein#PC00070;tight junction#PC00214 MONDO|Ensembl=ENSMODG00000050249.1|UniProtKB=A0A5F8HGV3 A0A5F8HGV3 TMEM265 PTHR48581:SF1 TRANSMEMBRANE PROTEIN 265 TRANSMEMBRANE PROTEIN 265 MONDO|Ensembl=ENSMODG00000005865.4|UniProtKB=F6T4R5 F6T4R5 FRMD1 PTHR13429:SF7 FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY FERM DOMAIN-CONTAINING PROTEIN 1 protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000037550.1|UniProtKB=A0A5F8H0A1 A0A5F8H0A1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000047932.1|UniProtKB=A0A5F8HE74 A0A5F8HE74 CNTF PTHR15196:SF0 CILIARY NEUROTROPHIC FACTOR CILIARY NEUROTROPHIC FACTOR molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083 biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;defense response#GO:0006952;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular developmental process#GO:0048869;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;regulation of response to stimulus#GO:0048583;regulation of cell projection organization#GO:0031344;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;inflammatory response#GO:0006954;cell activation#GO:0001775;positive regulation of cell projection organization#GO:0031346;cytokine-mediated signaling pathway#GO:0019221;nervous system development#GO:0007399;cell surface receptor signaling pathway via STAT#GO:0097696;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;regulation of response to wounding#GO:1903034;response to stress#GO:0006950;negative regulation of neuron apoptotic process#GO:0043524;gliogenesis#GO:0042063;multicellular organism development#GO:0007275;positive regulation of response to external stimulus#GO:0032103;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;signaling#GO:0023052;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;central nervous system development#GO:0007417;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of cellular response to stress#GO:0080135;response to peptide#GO:1901652;positive regulation of cellular component organization#GO:0051130;positive regulation of neuron projection development#GO:0010976;animal gross anatomical part developmental process#GO:0160108 axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell body#GO:0044297 MONDO|Ensembl=ENSMODG00000015643.4|UniProtKB=F7F166 F7F166 PTHR11480:SF33 SAPOSIN-RELATED PULMONARY SURFACTANT-ASSOCIATED PROTEIN B primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;late endosome#GO:0005770;organelle#GO:0043226 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000011703.4|UniProtKB=A0A5F8HC89 A0A5F8HC89 WDHD1 PTHR19932:SF10 WD REPEAT AND HMG-BOX DNA BINDING PROTEIN WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682 cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000046344.1|UniProtKB=A0A5F8GTA9 A0A5F8GTA9 VN2R641 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000036807.1|UniProtKB=A0A5F8GZ65 A0A5F8GZ65 PTHR44533:SF3 DEAD/H RNA HELICASE, PUTATIVE-RELATED ATP-DEPENDENT RNA HELICASE DDX60-RELATED double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723 response to external stimulus#GO:0009605;defense response#GO:0006952;response to virus#GO:0009615;defense response to virus#GO:0051607;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000050228.1|UniProtKB=A0A5F8H2K7 A0A5F8H2K7 UBXN1 PTHR46340:SF1 UBX DOMAIN-CONTAINING PROTEIN 1 UBX DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;binding#GO:0005488 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule metabolic process#GO:0010605;regulation of proteasomal protein catabolic process#GO:0061136;negative regulation of protein catabolic process#GO:0042177;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of protein ubiquitination#GO:0031396;regulation of protein modification process#GO:0031399;regulation of catabolic process#GO:0009894;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;negative regulation of biological process#GO:0048519;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;regulation of cellular process#GO:0050794;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of protein ubiquitination#GO:0031397;regulation of post-translational protein modification#GO:1901873;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000020128.4|UniProtKB=A0A5F8GCN8 A0A5F8GCN8 KIAA0825 PTHR33960:SF1 SIMILAR TO KIAA0825 PROTEIN KIAA0825 HOMOLOG MONDO|Ensembl=ENSMODG00000020077.2|UniProtKB=F7GI76 F7GI76 LOC100024996 PTHR48018:SF90 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AK3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000048510.1|UniProtKB=A0A5F8GKB4 A0A5F8GKB4 ZNF503 PTHR12522:SF3 ZINC-FINGER PROTEIN NOLZ1-RELATED ZINC FINGER PROTEIN 503 negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000006186.3|UniProtKB=F7AI63 F7AI63 EXOC3L1 PTHR21292:SF12 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3-LIKE PROTEIN SNARE binding#GO:0000149;binding#GO:0005488;protein binding#GO:0005515 transport#GO:0006810;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;exocytosis#GO:0006887;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352 cell periphery#GO:0071944;cell cortex#GO:0005938;cytoplasm#GO:0005737;exocyst#GO:0000145;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000024851.2|UniProtKB=F7AXG2 F7AXG2 PTHR21641:SF0 TRANSLATION INITIATION FACTOR-RELATED RNA-BINDING PROTEIN EIF1AD-RELATED intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 translation initiation factor#PC00224;translation factor#PC00223 MONDO|Ensembl=ENSMODG00000045198.1|UniProtKB=A0A5F8GS31 A0A5F8GS31 BTG2 PTHR22978:SF29 B-CELL TRANSLOCATION GENE PROTEIN BTG2 negative regulation of cellular process#GO:0048523;negative regulation of cell population proliferation#GO:0008285;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000037211.1|UniProtKB=A0A5F8HAP3 A0A5F8HAP3 RPL32 PTHR23413:SF1 60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N 60S RIBOSOMAL PROTEIN L32 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000013321.4|UniProtKB=F7GJG2 F7GJG2 QARS1 PTHR43097:SF16 GLUTAMINE-TRNA LIGASE GLUTAMINE--TRNA LIGASE ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538 catalytic complex#GO:1902494;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 aminoacyl-tRNA synthetase#PC00047 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 MONDO|Ensembl=ENSMODG00000045049.1|UniProtKB=A0A5F8G3V6 A0A5F8G3V6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000039791.1|UniProtKB=K7DYR2 K7DYR2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000019811.4|UniProtKB=F7C8F2 F7C8F2 LOC103099491 PTHR24376:SF85 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 600-RELATED negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016143.4|UniProtKB=F7D7F7 F7D7F7 LUZP1 PTHR23166:SF7 FILAMIN/GPBP-INTERACTING PROTEIN LEUCINE ZIPPER PROTEIN 1 protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to cytoskeleton#GO:0044380;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000009498.4|UniProtKB=A0A5F8GXC9 A0A5F8GXC9 TNS3 PTHR45734:SF5 TENSIN TENSIN-3 positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;anchoring junction#GO:0070161 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000006791.5|UniProtKB=F6PH42 F6PH42 OTOG PTHR11339:SF228 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED OTOGELIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000023487.2|UniProtKB=F7EZV6 F7EZV6 PTHR23138:SF94 RAN BINDING PROTEIN RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN intracellular transport#GO:0046907;nucleocytoplasmic transport#GO:0006913;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;nuclear transport#GO:0051169;nuclear export#GO:0051168;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007225.5|UniProtKB=F6WCT4 F6WCT4 MSC PTHR23349:SF62 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST MUSCULIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 muscle tissue development#GO:0060537;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;muscle organ development#GO:0007517;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;skeletal muscle tissue development#GO:0007519;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000014331.5|UniProtKB=F6ULL3 F6ULL3 DDX46 PTHR24031:SF25 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX46-RELATED metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000017842.3|UniProtKB=F6Z8E3 F6Z8E3 CALHM6 PTHR32261:SF4 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 6 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000018918.4|UniProtKB=F7GK10 F7GK10 ADAD1 PTHR10910:SF103 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN ADENOSINE DEAMINASE DOMAIN-CONTAINING PROTEIN 1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;adenosine deaminase activity#GO:0004000;binding#GO:0005488;nucleic acid binding#GO:0003676;tRNA-specific adenosine deaminase activity#GO:0008251;double-stranded RNA binding#GO:0003725 nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;base conversion or substitution editing#GO:0016553;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;adenosine to inosine editing#GO:0006382;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000008664.4|UniProtKB=F6PG51 F6PG51 TRMT5 PTHR23245:SF44 TRNA METHYLTRANSFERASE TRNA (GUANINE(37)-N(1))-METHYLTRANSFERASE RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;mitochondrial RNA modification#GO:1900864;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;mitochondrial RNA metabolic process#GO:0000959;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;methylation#GO:0032259;mitochondrial gene expression#GO:0140053;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA methylation#GO:0030488;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000018942.4|UniProtKB=F7GB24 F7GB24 PRDM5 PTHR23226:SF413 ZINC FINGER AND SCAN DOMAIN-CONTAINING PR DOMAIN ZINC FINGER PROTEIN 5 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011362.3|UniProtKB=F6T5A0 F6T5A0 SRSF5 PTHR23147:SF237 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 5 ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000016493.4|UniProtKB=H9H6W7 H9H6W7 PTHR22951:SF11 CLATHRIN ASSEMBLY PROTEIN PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;SNARE binding#GO:0000149;clathrin binding#GO:0030276 clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;membrane organization#GO:0061024;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234 coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;synaptic membrane#GO:0097060;clathrin-coated vesicle#GO:0030136;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane region#GO:0098590;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503 vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000000144.6|UniProtKB=F7A9R7 F7A9R7 KIF21B PTHR24115:SF893 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF21B macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000017506.4|UniProtKB=F7F0X2 F7F0X2 LOC103095354 PTHR11430:SF142 LIPOCALIN LIPOCALIN_CYTOSOLIC FATTY-ACID BINDING DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000002822.3|UniProtKB=F7EJ40 F7EJ40 IGF2BP2 PTHR10288:SF93 KH DOMAIN CONTAINING RNA BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 2 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;negative regulation of catabolic process#GO:0009895;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;nervous system development#GO:0007399;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;regulation of mRNA metabolic process#GO:1903311;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;animal gross anatomical part developmental process#GO:0160108;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA stabilization#GO:0043489;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000010754.5|UniProtKB=F7FWI4 F7FWI4 MARCHF8 PTHR45981:SF4 LD02310P E3 UBIQUITIN-PROTEIN LIGASE MARCHF8 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;binding#GO:0005488;signaling receptor binding#GO:0005102;acyltransferase activity#GO:0016746;MHC protein binding#GO:0042287;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;immune response#GO:0006955;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;response to stimulus#GO:0050896;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;antigen processing and presentation#GO:0019882;immune system process#GO:0002376;protein modification by small protein conjugation or removal#GO:0070647 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902;early endosome membrane#GO:0031901 MONDO|Ensembl=ENSMODG00000016794.4|UniProtKB=F7G5X8 F7G5X8 UPF2 PTHR12839:SF7 NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2 REGULATOR OF NONSENSE TRANSCRIPTS 2 primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;exon-exon junction complex#GO:0035145;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000007122.3|UniProtKB=A0A5F8HKT6 A0A5F8HKT6 OGFOD3 PTHR31837:SF3 CYTOCHROME B-245 CHAPERONE 1 CYTOCHROME B-245 CHAPERONE 1 metabolic process#GO:0008152;immune effector process#GO:0002252;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to other organism#GO:0051707;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000037917.1|UniProtKB=A0A5F8GWV8 A0A5F8GWV8 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007285.4|UniProtKB=F7FCH3 F7FCH3 WDR45B PTHR11227:SF18 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 3 small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266 macroautophagy#GO:0016236;macromolecule localization#GO:0033036;glycogen catabolic process#GO:0005980;intracellular protein localization#GO:0008104;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;vacuole organization#GO:0007033;localization#GO:0051179;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;cellular component assembly#GO:0022607;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;phagophore assembly site#GO:0000407 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000011224.4|UniProtKB=F7GAV7 F7GAV7 PTHR45697:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3 ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166 cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000047513.1|UniProtKB=F7E6F9 F7E6F9 LOC103098551 PTHR26453:SF712 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10H1-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003024.4|UniProtKB=A0A5F8G2D3 A0A5F8G2D3 CLCN3 PTHR45711:SF8 CHLORIDE CHANNEL PROTEIN H(+)_CL(-) EXCHANGE TRANSPORTER 3 monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;developmental maturation#GO:0021700;monoatomic anion transmembrane transport#GO:0098656;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;cellular homeostasis#GO:0019725;vesicle organization#GO:0016050;synaptic vesicle maturation#GO:0016188;cellular component organization or biogenesis#GO:0071840;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;developmental process#GO:0032502;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;chloride transport#GO:0006821;homeostatic process#GO:0042592;monoatomic anion transport#GO:0006820;cellular component organization#GO:0016043;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085 vacuole#GO:0005773;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;presynapse#GO:0098793;lysosomal membrane#GO:0005765;secretory vesicle#GO:0099503;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;lytic vacuole#GO:0000323;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;endosome#GO:0005768;endosome membrane#GO:0010008;plasma membrane#GO:0005886;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;synaptic vesicle#GO:0008021;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000037309.1|UniProtKB=A0A5F8H0S8 A0A5F8H0S8 PCLAF PTHR15679:SF8 PCNA-ASSOCIATED FACTOR PCNA-ASSOCIATED FACTOR metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translesion synthesis#GO:0019985;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA synthesis involved in DNA replication#GO:0090592;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000012944.4|UniProtKB=A0A5F8GLD5 A0A5F8GLD5 MST1 PTHR24261:SF12 PLASMINOGEN-RELATED HEPATOCYTE GROWTH FACTOR-LIKE PROTEIN-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;receptor tyrosine kinase binding#GO:0030971;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein modifying enzyme#PC00260;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000009005.2|UniProtKB=F7BQ41 F7BQ41 ATOX1 PTHR46365:SF1 COPPER TRANSPORT PROTEIN ATOX1 COPPER TRANSPORT PROTEIN ATOX1 molecular carrier activity#GO:0140104 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000005649.4|UniProtKB=A0A5F8GYL4 A0A5F8GYL4 ST6GALNAC4 PTHR45906:SF4 ALPHA-N-ACETYL-NEURAMINYL-2,3-BETA-GALACTOSYL-1, 3-N-ACETYL-GALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE-LIKE ALPHA-N-ACETYL-NEURAMINYL-2,3-BETA-GALACTOSYL-1,3-N-ACETYL-GALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757 glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;glycolipid biosynthetic process#GO:0009247;glycosphingolipid biosynthetic process#GO:0006688;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;oligosaccharide metabolic process#GO:0009311;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513 MONDO|Ensembl=ENSMODG00000044664.1|UniProtKB=A0A5F8H4W2 A0A5F8H4W2 ELF4 PTHR11849:SF170 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-4 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 MONDO|Ensembl=ENSMODG00000009296.4|UniProtKB=F6YXF4 F6YXF4 OLA1 PTHR23305:SF11 OBG GTPASE FAMILY OBG-LIKE ATPASE 1 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein#PC00020 MONDO|Ensembl=ENSMODG00000014677.4|UniProtKB=F7E7K4 F7E7K4 SLC35F2 PTHR14233:SF12 DUF914-RELATED QUEUINE_QUEUOSINE TRANSPORTER SLC35F2 MONDO|Ensembl=ENSMODG00000024951.1|UniProtKB=F6UTQ9 F6UTQ9 CRH PTHR15035:SF9 CORTICOLIBERIN/UROCORTIN CORTICOTROPIN-RELEASING HORMONE hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;binding#GO:0005488;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;neuropeptide receptor binding#GO:0071855;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of transport#GO:0051050;cellular process#GO:0009987;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of system process#GO:0044057;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;regulation of secretion#GO:0051046;cell communication#GO:0007154;regulation of hormone secretion#GO:0046883;positive regulation of signaling#GO:0023056;positive regulation of secretion#GO:0051047;positive regulation of hormone secretion#GO:0046887;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186 neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell body#GO:0044297 intercellular signal molecule#PC00207;peptide hormone#PC00179 Cortocotropin releasing factor receptor signaling pathway#P04380>CRF#P04454;Cortocotropin releasing factor receptor signaling pathway#P04380>ProCRF (Pro Corticotropin-Releasing Factor)#P04456 MONDO|Ensembl=ENSMODG00000001302.4|UniProtKB=F7BZW1 F7BZW1 RBM46 PTHR21245:SF3 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 46-RELATED RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000006771.4|UniProtKB=A0A5F8GE90 A0A5F8GE90 SLC22A3 PTHR24064:SF52 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000019113.2|UniProtKB=F7F990 F7F990 PTHR12015:SF103 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 4-LIKE receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677 cell surface receptor signaling pathway#GO:0007166;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;taxis#GO:0042330;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to peptide#GO:1901652;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of cell motility#GO:2000147;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;regulation of cell migration#GO:0030334;leukocyte migration#GO:0050900;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;response to other organism#GO:0051707;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;cell migration#GO:0016477;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cytokine-mediated signaling pathway#GO:0019221;cell chemotaxis#GO:0060326;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;regulation of cell motility#GO:2000145;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;cellular response to chemokine#GO:1990869;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cell motility#GO:0048870 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000042994.1|UniProtKB=A0A5F8G7H2 A0A5F8G7H2 ATPAF2 PTHR21013:SF10 ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000002685.4|UniProtKB=A0A5F8GHP2 A0A5F8GHP2 PTHR13459:SF3 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 MONDO|Ensembl=ENSMODG00000013470.3|UniProtKB=F7FMW6 F7FMW6 GMFG PTHR11249:SF4 GLIAL FACTOR NATURATION FACTOR GLIA MATURATION FACTOR GAMMA protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin nucleation#GO:0051125;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;negative regulation of biological process#GO:0048519;regulation of cellular process#GO:0050794;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;negative regulation of cytoskeleton organization#GO:0051494 actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000012375.4|UniProtKB=F7DHJ0 F7DHJ0 NFE2L1 PTHR24411:SF31 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR ENDOPLASMIC RETICULUM MEMBRANE SENSOR NFE2L1 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056 MONDO|Ensembl=ENSMODG00000009681.4|UniProtKB=F6YBU8 F6YBU8 DDX17 PTHR47958:SF215 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX17-RELATED RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000005399.4|UniProtKB=A0A5F8GFK5 A0A5F8GFK5 VIPAS39 PTHR13364:SF6 DEFECTIVE SPERMATOGENESIS PROTEIN 39 SPERMATOGENESIS-DEFECTIVE PROTEIN 39 HOMOLOG macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;intracellular protein transport#GO:0006886;transport#GO:0006810 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000001629.5|UniProtKB=A0A5F8H570 A0A5F8H570 RIC8B PTHR12425:SF2 SYNEMBRYN CHAPERONE RIC-8B guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000039232.1|UniProtKB=A0A5F8GEN4 A0A5F8GEN4 SRPK3 PTHR24055:SF578 MITOGEN-ACTIVATED PROTEIN KINASE EKC_KEOPS COMPLEX SUBUNIT BUD32 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000042391.1|UniProtKB=A0A5F8GHX2 A0A5F8GHX2 RAB30 PTHR47977:SF64 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-30 GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi cisterna#GO:0031985;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000004092.4|UniProtKB=F6VVP6 F6VVP6 EXT1 PTHR11062:SF97 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-1 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000005617.4|UniProtKB=F7CZ91 F7CZ91 SHOC1 PTHR35668:SF1 PROTEIN SHORTAGE IN CHIASMATA 1 ORTHOLOG PROTEIN SHORTAGE IN CHIASMATA 1 ORTHOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 organelle organization#GO:0006996;cellular process#GO:0009987;resolution of meiotic recombination intermediates#GO:0000712;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA recombination#GO:0006310;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;meiotic cell cycle process#GO:1903046;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;meiosis I#GO:0007127;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;reciprocal homologous recombination#GO:0140527;homologous recombination#GO:0035825;reproductive process#GO:0022414;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;sexual reproduction#GO:0019953;organelle fission#GO:0048285 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228 MONDO|Ensembl=ENSMODG00000008708.4|UniProtKB=A0A5F8GRW1 A0A5F8GRW1 BMAL1 PTHR23042:SF52 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS BASIC HELIX-LOOP-HELIX ARNT-LIKE PROTEIN 1 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;rhythmic process#GO:0048511;regulation of DNA-templated transcription#GO:0006355;circadian rhythm#GO:0007623;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 Circadian clock system#P00015>bmal1#G01504;Hypoxia response via HIF activation#P00030>HIF-1beta#P00820;Circadian clock system#P00015>BMAL1#P00506;Circadian clock system#P00015>bmal1#G01500 MONDO|Ensembl=ENSMODG00000011751.6|UniProtKB=F7G734 F7G734 HDAC5 PTHR10625:SF28 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 5 histone modifying activity#GO:0140993;catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213;histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824;deacylase activity#GO:0160215 regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;chromatin organization#GO:0006325;biological regulation#GO:0065007;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000019003.4|UniProtKB=A0A5F8HAR0 A0A5F8HAR0 PTHR23322:SF109 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 8 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000001750.4|UniProtKB=F6WZL4 F6WZL4 RNF149 PTHR22765:SF39 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF149 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endosome#GO:0005768 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000003508.4|UniProtKB=F7C8H6 F7C8H6 MSANTD1 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;nuclear body#GO:0016604;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000017159.3|UniProtKB=F6QDQ4 F6QDQ4 C1orf50 PTHR14553:SF1 UNCHARACTERIZED PROTEIN C1ORF50 SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 50 MONDO|Ensembl=ENSMODG00000025743.3|UniProtKB=K7E474 K7E474 LOC103106275 PTHR21312:SF28 SERINE PROTEASE INHIBITOR OVOINHIBITOR-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000005018.4|UniProtKB=A0A5F8HF78 A0A5F8HF78 PTHR24026:SF42 FAT ATYPICAL CADHERIN-RELATED PROTOCADHERIN FAT 1 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell-cell junction#GO:0005911 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000041793.1|UniProtKB=A0A5F8GGU3 A0A5F8GGU3 LOC100024561 PTHR11158:SF22 MSF1/PX19 RELATED PRELI DOMAIN CONTAINING PROTEIN 3B transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014 phospholipid transport#GO:0015914;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;lipid localization#GO:0010876 intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000002802.5|UniProtKB=F7EJI5 F7EJI5 KIF1B PTHR24115:SF328 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF1B protein binding#GO:0005515;plus-end-directed microtubule motor activity#GO:0008574;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 transport#GO:0006810;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;microtubule-based process#GO:0007017;vesicle cytoskeletal trafficking#GO:0099518;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;axo-dendritic transport#GO:0008088;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;vesicle-mediated transport#GO:0016192;cytoskeleton-dependent intracellular transport#GO:0030705;retrograde axonal transport#GO:0008090;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;axonal transport#GO:0098930;cellular localization#GO:0051641;localization#GO:0051179;cytosolic transport#GO:0016482;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656 vesicle#GO:0031982;intracellular vesicle#GO:0097708;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;axon#GO:0030424;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;microtubule#GO:0005874;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000047416.1|UniProtKB=A0A5F8GKQ8 A0A5F8GKQ8 LOC100021857 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027545.2|UniProtKB=K7E678 K7E678 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000041118.1|UniProtKB=A0A5F8GGX7 A0A5F8GGX7 TRAT1 PTHR15951:SF2 T-CELL RECEPTOR-ASSOCIATED TRANSMEMBRANE ADAPTER 1 T-CELL RECEPTOR-ASSOCIATED TRANSMEMBRANE ADAPTER 1 negative regulation of cellular process#GO:0048523;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of metabolic process#GO:0019222;positive regulation of immune system process#GO:0002684;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;negative regulation of signaling#GO:0023057;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;negative regulation of metabolic process#GO:0009892;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000005240.4|UniProtKB=A0A5F8GGF5 A0A5F8GGF5 SORBS1 PTHR14167:SF64 SH3 DOMAIN-CONTAINING SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 1 signaling adaptor activity#GO:0035591;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 organelle organization#GO:0006996;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membrane-bounded organelle#GO:0043227;cell junction#GO:0030054;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cell-substrate junction#GO:0030055;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000005480.4|UniProtKB=F7AID5 F7AID5 IRAK2 PTHR24419:SF2 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE-LIKE 2 catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;cellular response to lipopolysaccharide#GO:0071222;response to lipopolysaccharide#GO:0032496;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;cell surface receptor signaling pathway#GO:0007166;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;mitotic cell cycle#GO:0000278;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;positive regulation of signal transduction#GO:0009967;cellular response to biotic stimulus#GO:0071216;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to bacterium#GO:0009617;cytokine-mediated signaling pathway#GO:0019221;lipopolysaccharide-mediated signaling pathway#GO:0031663;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000016189.5|UniProtKB=A0A5F8GMF0 A0A5F8GMF0 MATN4 PTHR24020:SF14 COLLAGEN ALPHA MATRILIN-4 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000001483.4|UniProtKB=F7FHY3 F7FHY3 GAS7 PTHR23065:SF57 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 GROWTH ARREST-SPECIFIC PROTEIN 7 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;import into cell#GO:0098657;cell projection morphogenesis#GO:0048858;protein-containing complex organization#GO:0043933;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;cellular process#GO:0009987;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;endocytosis#GO:0006897;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;protein-containing complex assembly#GO:0065003;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;neurogenesis#GO:0022008;developmental process#GO:0032502;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;clathrin-dependent endocytosis#GO:0072583 intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000045213.1|UniProtKB=A0A5F8GSV5 A0A5F8GSV5 PTHR14562:SF3 TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT D TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT D nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 MONDO|Ensembl=ENSMODG00000005166.4|UniProtKB=A0A5F8G546 A0A5F8G546 CLEC16A PTHR21481:SF0 PROTEIN CLEC16A PROTEIN CLEC16A cellular localization#GO:0051641;localization#GO:0051179;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of autophagy#GO:0010506;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of catabolic process#GO:0009894;endosomal transport#GO:0016197;regulation of macroautophagy#GO:0016241;intracellular transport#GO:0046907;transport#GO:0006810;regulation of autophagosome maturation#GO:1901096;vacuolar transport#GO:0007034;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 organelle#GO:0043226;endomembrane system#GO:0012505;late endosome#GO:0005770;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endosome#GO:0005768 MONDO|Ensembl=ENSMODG00000038395.1|UniProtKB=A0A5F8HCJ5 A0A5F8HCJ5 PTHR11346:SF107 GALECTIN GALECTIN-7 binding#GO:0005488;carbohydrate binding#GO:0030246 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000018182.4|UniProtKB=F7FAT6 F7FAT6 CLSTN3 PTHR14139:SF5 CALSYNTENIN CALSYNTENIN-3 binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632 regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;positive regulation of cellular component organization#GO:0051130;cell adhesion#GO:0007155;regulation of biological quality#GO:0065008;regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;positive regulation of developmental process#GO:0051094;positive regulation of synapse assembly#GO:0051965;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;regulation of synapse assembly#GO:0051963 postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;cell surface#GO:0009986;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000043283.1|UniProtKB=A0A5F8G3P4 A0A5F8G3P4 PTHR37366:SF2 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 6 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 6 MONDO|Ensembl=ENSMODG00000017850.3|UniProtKB=F6Z7V6 F6Z7V6 PTHR24023:SF880 COLLAGEN ALPHA COLLAGEN ALPHA-1(X) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;interstitial matrix#GO:0005614;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000037330.1|UniProtKB=A0A5F8G5A8 A0A5F8G5A8 PTHR11021:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F SMALL NUCLEAR RIBONUCLEOPROTEIN F binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;cytoplasm#GO:0005737;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000014631.4|UniProtKB=F6YPQ7 F6YPQ7 PTHR35076:SF1 TUBULIN EPSILON AND DELTA COMPLEX PROTEIN 1 TUBULIN EPSILON AND DELTA COMPLEX PROTEIN 1 MONDO|Ensembl=ENSMODG00000002179.4|UniProtKB=F7GED8 F7GED8 DERL1 PTHR11009:SF1 DER1-LIKE PROTEIN, DERLIN DERLIN-1 response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;cellular process#GO:0009987;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000006372.4|UniProtKB=F7GCS7 F7GCS7 CNST PTHR28581:SF1 CONSORTIN CONSORTIN protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;regulation of vesicle-mediated transport#GO:0060627;regulation of protein localization#GO:0032880;regulation of transport#GO:0051049;regulation of establishment of protein localization#GO:0070201;regulation of localization#GO:0032879 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;endomembrane system#GO:0012505;transport vesicle#GO:0030133;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;plasma membrane#GO:0005886;Golgi apparatus#GO:0005794 MONDO|Ensembl=ENSMODG00000007185.3|UniProtKB=F6XAL7 F6XAL7 MRGPRE PTHR11334:SF26 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G PROTEIN-COUPLED RECEPTOR MEMBER E signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000047411.1|UniProtKB=A0A5F8H5X6 A0A5F8H5X6 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000046367.1|UniProtKB=A0A5F8HBY3 A0A5F8HBY3 PTHR24381:SF479 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 432 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011596.4|UniProtKB=F6UZC4 F6UZC4 ANKHD1 PTHR23206:SF5 MASK PROTEIN ANKYRIN REPEAT AND KH DOMAIN-CONTAINING PROTEIN 1 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000048617.1|UniProtKB=A0A5F8H261 A0A5F8H261 VN2R629 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000004225.4|UniProtKB=F6UBP3 F6UBP3 SLC4A2 PTHR11453:SF14 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN 2 chloride transmembrane transporter activity#GO:0015108;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;localization#GO:0051179;transmembrane transport#GO:0055085;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007 apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000046961.1|UniProtKB=A0A5F8H1K0 A0A5F8H1K0 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000015272.4|UniProtKB=F6TMI1 F6TMI1 CHFR PTHR16079:SF4 UBIQUITIN LIGASE PROTEIN CHFR E3 UBIQUITIN-PROTEIN LIGASE CHFR ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;regulation of cell cycle G2/M phase transition#GO:1902749;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000007637.4|UniProtKB=F7AYP6 F7AYP6 PCCA PTHR18866:SF130 CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE PROPIONYL-COA CARBOXYLASE ALPHA CHAIN, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity#GO:0016874 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;ligase#PC00142 Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033 MONDO|Ensembl=ENSMODG00000009147.5|UniProtKB=F7B0T8 F7B0T8 SKIDA1 PTHR23187:SF2 FLJ44216 PROTEIN-RELATED SKI_DACH DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000003140.4|UniProtKB=F6WUL8 F6WUL8 ADAMTS9 PTHR13723:SF33 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 9 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000003563.4|UniProtKB=A0A5F8GCG1 A0A5F8GCG1 DNAJC16 PTHR44303:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 16 DNAJ HOMOLOG SUBFAMILY C MEMBER 16 cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;regulation of biological quality#GO:0065008;process utilizing autophagic mechanism#GO:0061919;regulation of anatomical structure size#GO:0090066;metabolic process#GO:0008152;catabolic process#GO:0009056;biological regulation#GO:0065007;macroautophagy#GO:0016236;organelle organization#GO:0006996;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987 membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000002203.4|UniProtKB=A0A5F8GBC0 A0A5F8GBC0 ADAT1 PTHR46516:SF1 TRNA-SPECIFIC ADENOSINE DEAMINASE 1 TRNA-SPECIFIC ADENOSINE DEAMINASE 1 tRNA-specific adenosine deaminase activity#GO:0008251;catalytic activity, acting on a tRNA#GO:0140101;adenosine deaminase activity#GO:0004000;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000039435.1|UniProtKB=A0A5F8H9Y0 A0A5F8H9Y0 PTHR11910:SF1 ATP SYNTHASE DELTA CHAIN ATP SYNTHASE PERIPHERAL STALK SUBUNIT OSCP, MITOCHONDRIAL proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000017220.3|UniProtKB=F6WYC3 F6WYC3 NELFB PTHR13503:SF3 NEGATIVE ELONGATION FACTOR COMPLEX MEMBER B NEGATIVE ELONGATION FACTOR B negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;stem cell differentiation#GO:0048863;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000001843.3|UniProtKB=F6SPF9 F6SPF9 RAB29 PTHR24073:SF315 DRAB5-RELATED RAS-RELATED PROTEIN RAB-29 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;Golgi apparatus subcompartment#GO:0098791;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000000223.4|UniProtKB=F6SZ34 F6SZ34 ZNF330 PTHR13214:SF1 ZINC FINGER PROTEIN 330 ZINC FINGER PROTEIN 330 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000014066.4|UniProtKB=A0A5F8H3A4 A0A5F8H3A4 KIF9 PTHR24115:SF191 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF9 ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000049232.1|UniProtKB=A0A5F8GUH5 A0A5F8GUH5 PTHR13374:SF3 DET1 HOMOLOG DE-ETIOLATED-1 HOMOLOG DET1 HOMOLOG binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein binding#GO:0005515;ubiquitin-like protein ligase binding#GO:0044389;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin protein ligase binding#GO:0031625 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;protein ubiquitination#GO:0016567;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000014716.4|UniProtKB=F7D2Z4 F7D2Z4 FKBP10 PTHR46046:SF3 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP10 MONDO|Ensembl=ENSMODG00000003107.5|UniProtKB=F6PIF7 F6PIF7 SRSF6 PTHR23003:SF52 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE_ARGININE-RICH SPLICING FACTOR 6 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000003896.5|UniProtKB=F7D869 F7D869 PLPPR4 PTHR10165:SF13 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 4 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;phosphate-containing compound metabolic process#GO:0006796;cellular component organization#GO:0016043;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;metabolic process#GO:0008152;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;phospholipid dephosphorylation#GO:0046839;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;system development#GO:0048731;dephosphorylation#GO:0016311;cell communication#GO:0007154;anatomical structure development#GO:0048856;organophosphate metabolic process#GO:0019637;axon development#GO:0061564;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;lipid metabolic process#GO:0006629;neurogenesis#GO:0022008;lipid modification#GO:0030258;cellular developmental process#GO:0048869 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000019042.5|UniProtKB=F7AYX0 F7AYX0 TRERF1 PTHR16089:SF19 REST COREPRESSOR COREST PROTEIN-RELATED TRANSCRIPTIONAL-REGULATING FACTOR 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000005153.3|UniProtKB=A0A5F8GHB5 A0A5F8GHB5 RNF44 PTHR46171:SF2 GH10160P RING FINGER PROTEIN 44 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446 MONDO|Ensembl=ENSMODG00000024644.2|UniProtKB=F6XC00 F6XC00 SPTSSB PTHR28612:SF1 SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT B SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT B acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;ceramide metabolic process#GO:0006672;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;organelle organization#GO:0006996;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;endomembrane system organization#GO:0010256;biosynthetic process#GO:0009058 protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000012968.3|UniProtKB=A0A5F8GMJ7 A0A5F8GMJ7 DAG1 PTHR21559:SF22 DYSTROGLYCAN-RELATED DYSTROGLYCAN 1 protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631 developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon development#GO:0061564;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;tissue development#GO:0009888;system development#GO:0048731;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;muscle structure development#GO:0061061;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;morphogenesis of an epithelium#GO:0002009;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902 sarcolemma#GO:0042383;cell junction#GO:0030054;cell periphery#GO:0071944;external encapsulating structure#GO:0030312;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;extracellular matrix#GO:0031012;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;extracellular region#GO:0005576;basement membrane#GO:0005604;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000018452.1|UniProtKB=F7CUD2 F7CUD2 ATP6V1E1 PTHR45715:SF23 ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED ATPASE H+ TRANSPORTING V1 SUBUNIT E1 monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;proton-transporting two-sector ATPase complex#GO:0016469;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;vacuolar membrane#GO:0005774;transporter complex#GO:1990351 MONDO|Ensembl=ENSMODG00000011435.4|UniProtKB=F6RJT3 F6RJT3 NRSN1 PTHR14796:SF6 NEURENSIN 1-RELATED NEURENSIN-1 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;nervous system development#GO:0007399;multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856 transport vesicle#GO:0030133;endomembrane system#GO:0012505;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;intracellular vesicle#GO:0097708;cell body#GO:0044297;vesicle#GO:0031982 MONDO|Ensembl=ENSMODG00000008023.4|UniProtKB=F7CKY6 F7CKY6 ADRA1B PTHR24248:SF17 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-1B ADRENERGIC RECEPTOR G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signal transduction#GO:0007165;cellular process#GO:0009987;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of biological quality#GO:0065008;adrenergic receptor signaling pathway#GO:0071875;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 MONDO|Ensembl=ENSMODG00000038337.1|UniProtKB=A0A5F8HB75 A0A5F8HB75 BCDIN3D PTHR12315:SF1 BICOID-INTERACTING PROTEIN RELATED RNA 5'-MONOPHOSPHATE METHYLTRANSFERASE catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000016218.3|UniProtKB=H9H6T4 H9H6T4 LOC100015438 PTHR11929:SF11 ALPHA- 1,3 -FUCOSYLTRANSFERASE 4-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 3-ALPHA-L-FUCOSYLTRANSFERASE FUT5 hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;catalytic activity#GO:0003824;transferase activity#GO:0016740;alpha-(1->3)-fucosyltransferase activity#GO:0046920;glycosyltransferase activity#GO:0016757 glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000021465.4|UniProtKB=F7GDR9 F7GDR9 MYOM1 PTHR13817:SF16 TITIN MYOMESIN-1 binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198 anatomical structure morphogenesis#GO:0009653;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;muscle cell development#GO:0055001;cell development#GO:0048468;actomyosin structure organization#GO:0031032;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840 supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;A band#GO:0031672;contractile muscle fiber#GO:0043292;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;M band#GO:0031430;intracellular organelle#GO:0043229 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000013535.3|UniProtKB=F7CMK4 F7CMK4 ZFYVE21 PTHR39490:SF8 ARRESTIN DOMAIN-CONTAINING PROTEIN D ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 21 MONDO|Ensembl=ENSMODG00000021245.3|UniProtKB=F6TJE7 F6TJE7 DIPK2A PTHR32073:SF6 GH11358P DIVERGENT PROTEIN KINASE DOMAIN 2A regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;regulation of signaling#GO:0023051;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;coated membrane#GO:0048475;membrane coat#GO:0030117;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle coat#GO:0030120;cytoplasm#GO:0005737;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000043400.1|UniProtKB=K7E2B8 K7E2B8 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000023243.1|UniProtKB=F6TWW3 F6TWW3 AMIGO1 PTHR24368:SF1 AMPHOTERIN-INDUCED PROTEIN AMPHOTERIN-INDUCED PROTEIN 1 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106 animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;developmental process#GO:0032502;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;system development#GO:0048731;cell-cell adhesion#GO:0098609;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;brain development#GO:0007420;head development#GO:0060322;nervous system development#GO:0007399 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell body#GO:0044297;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 MONDO|Ensembl=ENSMODG00000048411.1|UniProtKB=A0A5F8H6T3 A0A5F8H6T3 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000043802.1|UniProtKB=F6YJH7 F6YJH7 PTHR26452:SF812 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AC2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001506.4|UniProtKB=F7F4G0 F7F4G0 ANGPTL3 PTHR19143:SF222 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 3 molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857 phospholipid metabolic process#GO:0006644;homeostatic process#GO:0042592;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;lipid homeostasis#GO:0055088;organophosphate catabolic process#GO:0046434;triglyceride homeostasis#GO:0070328;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;cholesterol homeostasis#GO:0042632;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;metabolic process#GO:0008152 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000017255.5|UniProtKB=A0A5F8HKG2 A0A5F8HKG2 PHACTR2 PTHR12751:SF5 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 2 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515 actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based process#GO:0030029 phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000002365.4|UniProtKB=A0A5F8G9K4 A0A5F8G9K4 ATP8B4 PTHR24092:SF80 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IM-RELATED intramembrane lipid carrier activity#GO:0140303;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 cellular component organization#GO:0016043;Golgi organization#GO:0007030;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;lipid transport#GO:0006869;phospholipid transport#GO:0015914;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035 membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000047773.1|UniProtKB=A0A5F8H1Y6 A0A5F8H1Y6 CLIC2 PTHR43920:SF4 CHLORIDE INTRACELLULAR CHANNEL, ISOFORM A CHLORIDE INTRACELLULAR CHANNEL PROTEIN 2 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253 chloride transport#GO:0006821;monoatomic anion transport#GO:0006820;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000005542.4|UniProtKB=F7FHR7 F7FHR7 SH2D3C PTHR14247:SF6 BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN SH2 DOMAIN-CONTAINING PROTEIN 3C MONDO|Ensembl=ENSMODG00000048589.1|UniProtKB=A0A5F8HE92 A0A5F8HE92 RD3 PTHR28489:SF1 RENTINAL DEGENERATION 3-LIKE PROTEIN RD3 sensory system development#GO:0048880;visual system development#GO:0150063;retina development in camera-type eye#GO:0060041;multicellular organismal process#GO:0032501;developmental process#GO:0032502;sensory organ development#GO:0007423;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;eye development#GO:0001654;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513 MONDO|Ensembl=ENSMODG00000001280.4|UniProtKB=F7CIF8 F7CIF8 SAMHD1 PTHR11373:SF48 DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 response to virus#GO:0009615;organophosphate catabolic process#GO:0046434;regulation of defense response#GO:0031347;purine nucleotide catabolic process#GO:0006195;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;regulation of response to biotic stimulus#GO:0002831;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;response to external biotic stimulus#GO:0043207;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;regulation of innate immune response#GO:0045088;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of response to stress#GO:0080134;nucleotide catabolic process#GO:0009166;regulation of response to stimulus#GO:0048583;response to other organism#GO:0051707;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;nucleotide metabolic process#GO:0009117;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;biological process involved in interspecies interaction between organisms#GO:0044419;phosphorus metabolic process#GO:0006793;defense response to virus#GO:0051607;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;regulation of response to external stimulus#GO:0032101;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000016269.4|UniProtKB=F7BH91 F7BH91 CSE1L PTHR10997:SF8 IMPORTIN-7, 8, 11 EXPORTIN-2 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein export from nucleus#GO:0006611 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle envelope#GO:0031967;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 MONDO|Ensembl=ENSMODG00000012602.4|UniProtKB=A0A5F8GHI8 A0A5F8GHI8 STARD3NL PTHR46121:SF1 STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE STARD3 N-TERMINAL-LIKE PROTEIN alcohol binding#GO:0043178;lipid binding#GO:0008289;steroid binding#GO:0005496;cholesterol binding#GO:0015485;small molecule binding#GO:0036094;binding#GO:0005488;sterol binding#GO:0032934 lipid transport#GO:0006869;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;localization#GO:0051179;sterol transport#GO:0015918;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;transport#GO:0006810 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;late endosome membrane#GO:0031902;endoplasmic reticulum#GO:0005783;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;organelle membrane contact site#GO:0044232;intracellular vesicle#GO:0097708;vesicle#GO:0031982 MONDO|Ensembl=ENSMODG00000049679.1|UniProtKB=A0A5F8GEQ4 A0A5F8GEQ4 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014720.3|UniProtKB=F6ZD92 F6ZD92 HNRNPA0 PTHR48024:SF71 GEO13361P1-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A0 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000001060.4|UniProtKB=F6YRF8 F6YRF8 PTHR24256:SF219 TRYPTASE-RELATED SERINE PROTEASE 33 catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000051496.1|UniProtKB=F6V1F2 F6V1F2 PTHR48002:SF176 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017376.3|UniProtKB=F6VIB3 F6VIB3 ILF2 PTHR46447:SF1 INTERLEUKIN ENHANCER-BINDING FACTOR INTERLEUKIN ENHANCER-BINDING FACTOR 2 binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;DNA binding#GO:0003677;RNA binding#GO:0003723 regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000018822.4|UniProtKB=F6YYR3 F6YYR3 MCM3 PTHR11630:SF106 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM3 catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094 nucleobase-containing compound metabolic process#GO:0006139;double-strand break repair via break-induced replication#GO:0000727;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;mitotic cell cycle process#GO:1903047;DNA metabolic process#GO:0006259;nuclear DNA replication#GO:0033260;mitotic DNA replication#GO:1902969;cell cycle DNA replication#GO:0044786;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA replication initiation#GO:0006270;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;cell cycle process#GO:0022402;DNA-templated DNA replication#GO:0006261;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;MCM complex#GO:0042555;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000025228.2|UniProtKB=F7FJU0 F7FJU0 CCIN PTHR24412:SF163 KELCH PROTEIN CALICIN ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006067.4|UniProtKB=A0A5F8GCI6 A0A5F8GCI6 PPFIBP2 PTHR12587:SF18 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-BETA-2 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 neuromuscular junction development#GO:0007528;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 presynaptic active zone#GO:0048786;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;presynapse#GO:0098793 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000015303.4|UniProtKB=F6QD02 F6QD02 PLEKHA8 PTHR10219:SF111 GLYCOLIPID TRANSFER PROTEIN-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8 anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;lipid carrier activity#GO:0005319;ion binding#GO:0043167;molecular carrier activity#GO:0140104;phospholipid transfer activity#GO:0120014;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;phospholipid binding#GO:0005543;transporter activity#GO:0005215 cellular localization#GO:0051641;localization#GO:0051179;lipid localization#GO:0010876;ceramide transport#GO:0035627;cellular component organization#GO:0016043;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular transport#GO:0046907;transport#GO:0006810;lipid transport#GO:0006869;membrane organization#GO:0061024;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000037624.1|UniProtKB=A0A5F8H253 A0A5F8H253 PTHR10424:SF82 VIRAL ENVELOPE PROTEIN ENVELOPE POLYPROTEIN myoblast fusion#GO:0007520;cellular process#GO:0009987;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;cell-cell fusion#GO:0140253;developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;syncytium formation by cell-cell fusion#GO:0000768;striated muscle cell differentiation#GO:0051146 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000051425.1|UniProtKB=F7BM42 F7BM42 PTHR24388:SF119 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 648 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000014364.4|UniProtKB=F6TPE3 F6TPE3 PTHR11787:SF4 RAB GDP-DISSOCIATION INHIBITOR CHM, RAB ESCORT PROTEIN 1 protein targeting to membrane#GO:0006612;transport#GO:0006810;localization within membrane#GO:0051668;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;protein targeting#GO:0006605 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000016220.3|UniProtKB=F7FM06 F7FM06 FITM2 PTHR23129:SF1 ACYL-COENZYME A DIPHOSPHATASE FITM2 ACYL-COENZYME A DIPHOSPHATASE FITM2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular component organization or biogenesis#GO:0071840;lipid droplet organization#GO:0034389;organelle assembly#GO:0070925;chemical homeostasis#GO:0048878;cellular component assembly#GO:0022607;homeostatic process#GO:0042592;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;lipid homeostasis#GO:0055088;lipid storage#GO:0019915;cellular process#GO:0009987 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000014715.3|UniProtKB=F7D304 F7D304 CDCA4 PTHR16277:SF6 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 CELL DIVISION CYCLE-ASSOCIATED PROTEIN 4 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000023086.2|UniProtKB=F7BNV4 F7BNV4 PTHR43128:SF10 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A CHAIN oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;energy derivation by oxidation of organic compounds#GO:0015980;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000046760.1|UniProtKB=A0A5F8G723 A0A5F8G723 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000014040.4|UniProtKB=F6UQF2 F6UQF2 EXTL1 PTHR11062:SF8 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-LIKE 1 glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000008396.4|UniProtKB=F7BV11 F7BV11 MYO3B PTHR46256:SF1 AGAP011099-PA MYOSIN-IIIB isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;protein serine/threonine kinase activity#GO:0004674 regulation of filopodium assembly#GO:0051489;system process#GO:0003008;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of cell projection assembly#GO:0060491;positive regulation of cell projection organization#GO:0031346;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular component biogenesis#GO:0044089;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of biological quality#GO:0065008;nervous system process#GO:0050877;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;sensory perception of sound#GO:0007605;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 intracellular membraneless organelle#GO:0043232;neuron projection#GO:0043005;membraneless organelle#GO:0043228;stereocilium#GO:0032420;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;filopodium#GO:0030175;photoreceptor inner segment#GO:0001917 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522 MONDO|Ensembl=ENSMODG00000050308.1|UniProtKB=A0A5F8GHV1 A0A5F8GHV1 PTHR24377:SF1056 IP01015P-RELATED ZINC FINGER PROTEIN 41 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010099.4|UniProtKB=F6X583 F6X583 GATA1 PTHR10071:SF190 TRANSCRIPTION FACTOR GATA FAMILY MEMBER ERYTHROID TRANSCRIPTION FACTOR sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000005754.2|UniProtKB=F6QDT6 F6QDT6 PTHR34344:SF1 UPF0184 PROTEIN C9ORF16 BUBLIN COILED-COIL PROTEIN intermediate filament organization#GO:0045109;intermediate filament bundle assembly#GO:0045110;intermediate filament-based process#GO:0045103;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104;cellular component assembly#GO:0022607 organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000007259.4|UniProtKB=F6VWC1 F6VWC1 CRYM PTHR13812:SF25 KETIMINE REDUCTASE MU-CRYSTALLIN KETIMINE REDUCTASE MU-CRYSTALLIN hormone binding#GO:0042562;binding#GO:0005488 biological regulation#GO:0065007;hormone metabolic process#GO:0042445;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958;modified amino acid metabolic process#GO:0006575;regulation of biological quality#GO:0065008;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000048986.1|UniProtKB=A0A5F8HFT5 A0A5F8HFT5 PTHR11346:SF80 GALECTIN GALECTIN-9B carbohydrate binding#GO:0030246;carbohydrate derivative binding#GO:0097367;binding#GO:0005488 negative regulation of multicellular organismal process#GO:0051241;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of T cell proliferation#GO:0042129;regulation of macromolecule metabolic process#GO:0060255;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of cell population proliferation#GO:0008285;negative regulation of biosynthetic process#GO:0009890;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of cell adhesion#GO:0007162;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cell activation#GO:0050866;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of lymphocyte activation#GO:0051249;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of mononuclear cell proliferation#GO:0032944;negative regulation of lymphocyte activation#GO:0051250;negative regulation of leukocyte activation#GO:0002695;regulation of multicellular organismal process#GO:0051239;negative regulation of cell-cell adhesion#GO:0022408;positive regulation of macromolecule metabolic process#GO:0010604;regulation of T cell activation#GO:0050863;negative regulation of T cell proliferation#GO:0042130;regulation of leukocyte proliferation#GO:0070663 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000008204.4|UniProtKB=A0A5F8GFN6 A0A5F8GFN6 SRP68 PTHR12860:SF0 SIGNAL RECOGNITION PARTICLE 68 KDA PROTEIN SIGNAL RECOGNITION PARTICLE SUBUNIT SRP68 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein targeting#GO:0006605;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;protein targeting to ER#GO:0045047 ribonucleoprotein complex#GO:1990904;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000009255.4|UniProtKB=A0A5F8H514 A0A5F8H514 DDC PTHR11999:SF167 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE AROMATIC-L-AMINO-ACID DECARBOXYLASE carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 serotonin biosynthetic process#GO:0042427;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;phenol-containing compound biosynthetic process#GO:0046189;amine metabolic process#GO:0009308;phenol-containing compound metabolic process#GO:0018958;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987;catecholamine metabolic process#GO:0006584;serotonin metabolic process#GO:0042428;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;lyase#PC00144 Nicotine pharmacodynamics pathway#P06587>DDC#P06608;Dopamine receptor mediated signaling pathway#P05912>DOPA decarb.#P05961;Adrenaline and noradrenaline biosynthesis#P00001>DOPA decarb.#P00066;5-Hydroxytryptamine biosynthesis#P04371>Aromatic L-amino acid decarboxylase#P04400 MONDO|Ensembl=ENSMODG00000029176.2|UniProtKB=K7E273 K7E273 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000020101.4|UniProtKB=F6Z5W2 F6Z5W2 SLC43A1 PTHR20766:SF0 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 4-LIKE ISOFORM X1 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;neutral L-amino acid transmembrane transporter activity#GO:0015175;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 amino acid transport#GO:0006865;transport#GO:0006810;establishment of localization#GO:0051234;neutral amino acid transport#GO:0015804;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000041575.1|UniProtKB=A0A5F8H2G9 A0A5F8H2G9 APOD PTHR10612:SF65 APOLIPOPROTEIN D APOLIPOPROTEIN D alcohol binding#GO:0043178;lipid binding#GO:0008289;steroid binding#GO:0005496;cholesterol binding#GO:0015485;binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934 response to oxygen-containing compound#GO:1901700;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;response to chemical#GO:0042221;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 apolipoprotein#PC00052 MONDO|Ensembl=ENSMODG00000048960.1|UniProtKB=F6RN91 F6RN91 LOC100021126 PTHR48018:SF32 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5L1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017218.3|UniProtKB=F6WYH2 F6WYH2 PTHR21580:SF25 SHIPPO-1-RELATED PROTEIN STPG3 cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;sperm motility#GO:0097722;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000007910.3|UniProtKB=F7GIJ8 F7GIJ8 PTHR24377:SF710 IP01015P-RELATED ZINC FINGER PROTEIN 181-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009145.4|UniProtKB=F7B0V3 F7B0V3 SH3BP5L PTHR19423:SF8 SH3 DOMAIN-BINDING PROTEIN 5 SH3 DOMAIN-BINDING PROTEIN 5-LIKE enzyme inhibitor activity#GO:0004857;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase inhibitor activity#GO:0019210;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;guanyl-nucleotide exchange factor activity#GO:0005085;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017916.4|UniProtKB=F7F2C1 F7F2C1 KIAA0319L PTHR46182:SF3 FI19480P1 DYSLEXIA-ASSOCIATED PROTEIN KIAA0319-LIKE PROTEIN cellular process#GO:0009987;nervous system development#GO:0007399;cell differentiation#GO:0030154;cell motility#GO:0048870;cell migration#GO:0016477;multicellular organismal process#GO:0032501;developmental process#GO:0032502;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neurogenesis#GO:0022008;neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000017786.3|UniProtKB=A0A5F8GRM3 A0A5F8GRM3 LDHB PTHR43128:SF2 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE B CHAIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid catabolic process#GO:0072329;pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;generation of precursor metabolites and energy#GO:0006091 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000008219.2|UniProtKB=A0A5F8GS87 A0A5F8GS87 PTHR45696:SF10 60S ACIDIC RIBOSOMAL PROTEIN P1 LARGE RIBOSOMAL SUBUNIT PROTEIN P1 molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209;binding#GO:0005488;structural molecule activity#GO:0005198;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;structural constituent of ribosome#GO:0003735 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000040752.1|UniProtKB=F6VJX1 F6VJX1 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000015603.5|UniProtKB=F6Z5M6 F6Z5M6 RIMBP2 PTHR14234:SF18 RIM BINDING PROTEIN-RELATED RIMS-BINDING PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of transport#GO:0051049 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cell cortex#GO:0005938;presynapse#GO:0098793;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;presynaptic active zone#GO:0048786 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000036838.1|UniProtKB=A0A5F8G7Q4 A0A5F8G7Q4 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000021503.3|UniProtKB=F7G2N9 F7G2N9 TTC39C PTHR31859:SF24 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39C anatomical structure development#GO:0048856;cilium organization#GO:0044782;ear development#GO:0043583;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;embryonic organ development#GO:0048568;cell projection organization#GO:0030030;animal organ morphogenesis#GO:0009887;sensory organ morphogenesis#GO:0090596;cilium assembly#GO:0060271;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;sensory organ development#GO:0007423;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;embryo development#GO:0009790;plasma membrane bounded cell projection organization#GO:0120036;inner ear morphogenesis#GO:0042472;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;inner ear development#GO:0048839;cell projection assembly#GO:0030031;cellular process#GO:0009987 MONDO|Ensembl=ENSMODG00000014755.4|UniProtKB=A0A5F8GRK9 A0A5F8GRK9 EPX PTHR11475:SF145 OXIDASE/PEROXIDASE EOSINOPHIL PEROXIDASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824 response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 MONDO|Ensembl=ENSMODG00000006103.4|UniProtKB=F7F0S7 F7F0S7 FAAH2 PTHR43372:SF4 FATTY-ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 2 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000002506.4|UniProtKB=F7B9E4 F7B9E4 IGF1 PTHR46845:SF1 INSULIN-LIKE GROWTH FACTOR I INSULIN-LIKE GROWTH FACTOR 1 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;hormone activity#GO:0005179;molecular function activator activity#GO:0140677 positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cell population proliferation#GO:0008283;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of cellular process#GO:0048522;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;insulin-like growth factor receptor signaling pathway#GO:0048009;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>IGF-1#P06854;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Insulin IGF#P00896 MONDO|Ensembl=ENSMODG00000009771.4|UniProtKB=F6TFA3 F6TFA3 VWA2 PTHR24020:SF37 COLLAGEN ALPHA VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 2 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 MONDO|Ensembl=ENSMODG00000017116.3|UniProtKB=F6UJE8 F6UJE8 GNAI1 PTHR10218:SF359 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-1 ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;protein binding#GO:0005515;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;signaling receptor binding#GO:0005102;GTPase activity#GO:0003924 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562 heterotrimeric G-protein#PC00117;G-protein#PC00020 PI3 kinase pathway#P00048>Galpha#P01199;Enkephalin release#P05913>G-Protein (i)#P05974;Gonadotropin-releasing hormone receptor pathway#P06664>gnai#P06807;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Nicotine pharmacodynamics pathway#P06587>GNAI#P06609;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;GABA-B receptor II signaling#P05731>Gi/oalpha#P05757;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;Opioid prodynorphin pathway#P05916>G-protein#P06002;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Opioid proenkephalin pathway#P05915>G-protein#P05994;Gonadotropin-releasing hormone receptor pathway#P06664>gnai/o#P06773;Endogenous cannabinoid signaling#P05730>Galpha#P05751 MONDO|Ensembl=ENSMODG00000042275.1|UniProtKB=A0A5F8GVW4 A0A5F8GVW4 PTHR15162:SF9 ASPARTOACYLASE ASPARTOACYLASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000050513.1|UniProtKB=A0A5F8GIM1 A0A5F8GIM1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000047687.1|UniProtKB=K7DZX0 K7DZX0 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000024483.2|UniProtKB=F7GFE9 F7GFE9 PTHR10356:SF5 ALLOGRAFT INFLAMMATORY FACTOR-1 ALLOGRAFT INFLAMMATORY FACTOR 1-LIKE cytoskeletal protein binding#GO:0008092;metal ion binding#GO:0046872;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;actin binding#GO:0003779;calcium ion binding#GO:0005509;actin filament binding#GO:0051015 cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;cellular component organization#GO:0016043;cell projection organization#GO:0030030;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435 ruffle#GO:0001726;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;ruffle membrane#GO:0032587;cytoskeleton#GO:0005856;actin filament#GO:0005884;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;cell projection membrane#GO:0031253;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;leading edge membrane#GO:0031256;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;actin cytoskeleton#GO:0015629 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000027618.2|UniProtKB=K7E075 K7E075 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008581.2|UniProtKB=F7CCX2 F7CCX2 SSR4 PTHR12731:SF1 TRANSLOCON-ASSOCIATED PROTEIN, DELTA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT DELTA endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000036685.1|UniProtKB=A0A5F8GIG9 A0A5F8GIG9 monDomV1R1284 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000036645.1|UniProtKB=A0A5F8HK58 A0A5F8HK58 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000004222.4|UniProtKB=A0A5F8G1Y4 A0A5F8G1Y4 PUS3 PTHR11142:SF5 PSEUDOURIDYLATE SYNTHASE TRNA PSEUDOURIDINE(38_39) SYNTHASE isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;intramolecular transferase activity#GO:0016866 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA modification#GO:0016556;pseudouridine synthesis#GO:0001522;tRNA modification#GO:0006400;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 lyase#PC00144 MONDO|Ensembl=ENSMODG00000014346.4|UniProtKB=A0A5F8HDU1 A0A5F8HDU1 ZNF711 PTHR24403:SF107 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 521-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000027868.2|UniProtKB=K7E6D2 K7E6D2 LOC103095140 PTHR24390:SF250 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 763 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000007264.4|UniProtKB=F7FQX8 F7FQX8 ATP1B2 PTHR11523:SF26 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671 import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;export from cell#GO:0140352;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;transmembrane transport#GO:0055085;potassium ion homeostasis#GO:0055075;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878 ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cation-transporting ATPase complex#GO:0090533;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000007406.4|UniProtKB=F7BNC9 F7BNC9 PTHR24377:SF1028 IP01015P-RELATED ZINC FINGER PROTEIN 84 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025530.3|UniProtKB=F6V218 F6V218 NMU PTHR15390:SF0 NEUROMEDIN-U NEUROMEDIN-U protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;neuropeptide receptor binding#GO:0071855;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of smooth muscle contraction#GO:0006940;regulation of system process#GO:0044057;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of trans-synaptic signaling#GO:0099177;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;regulation of muscle contraction#GO:0006937;positive regulation of synaptic transmission#GO:0050806;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;regulation of muscle system process#GO:0090257;neuropeptide signaling pathway#GO:0007218 neuron projection#GO:0043005;presynapse#GO:0098793;neuron projection terminus#GO:0044306;cell projection#GO:0042995;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;synapse#GO:0045202;cellular anatomical structure#GO:0110165;axon#GO:0030424;axon terminus#GO:0043679;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000006601.4|UniProtKB=F6ZWZ1 F6ZWZ1 RGL3 PTHR23113:SF220 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE 3 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000002662.4|UniProtKB=F7DHX9 F7DHX9 FSCN2 PTHR10551:SF9 FASCIN FASCIN-2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cell migration#GO:0016477;cellular component assembly#GO:0022607;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;supramolecular fiber organization#GO:0097435 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000004238.5|UniProtKB=F6YV60 F6YV60 KCNJ3 PTHR11767:SF16 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 1 ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;transport#GO:0006810;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724;GABA-B receptor II signaling#P05731>K channel#P05758;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083 MONDO|Ensembl=ENSMODG00000017147.4|UniProtKB=F6TM33 F6TM33 NHS PTHR23039:SF5 NANCE-HORAN SYNDROME PROTEIN ACTIN REMODELING REGULATOR NHS system development#GO:0048731;eye development#GO:0001654;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;sensory organ development#GO:0007423;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;visual system development#GO:0150063;multicellular organismal process#GO:0032501;sensory system development#GO:0048880 MONDO|Ensembl=ENSMODG00000037928.1|UniProtKB=A0A5F8GZP1 A0A5F8GZP1 LOC100618397 PTHR24377:SF878 IP01015P-RELATED ZINC FINGER PROTEIN 670 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000048554.1|UniProtKB=A0A5F8GL03 A0A5F8GL03 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007062.5|UniProtKB=F6PV08 F6PV08 PTHR10048:SF28 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT ALPHA catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;cell migration#GO:0016477;biological regulation#GO:0065007;biosynthetic process#GO:0009058;intracellular signaling cassette#GO:0141124;organophosphate metabolic process#GO:0019637;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;signal transduction#GO:0007165;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;intracellular signal transduction#GO:0035556;phosphatidylinositol phosphate biosynthetic process#GO:0046854;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;phospholipid biosynthetic process#GO:0008654;cell motility#GO:0048870;regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;Integrin signalling pathway#P00034>PI3K#P00936;Axon guidance mediated by netrin#P00009>PI3K#P00363;VEGF signaling pathway#P00056>PI3K#P01413;Angiogenesis#P00005>PI3K#P00236;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;EGF receptor signaling pathway#P00018>PI3K#P00557 MONDO|Ensembl=ENSMODG00000029281.2|UniProtKB=K7E5R3 K7E5R3 PTHR10424:SF82 VIRAL ENVELOPE PROTEIN ENVELOPE POLYPROTEIN anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;syncytium formation by cell-cell fusion#GO:0000768;striated muscle cell differentiation#GO:0051146;animal gross anatomical part developmental process#GO:0160108;cell-cell fusion#GO:0140253;developmental process#GO:0032502;muscle structure development#GO:0061061;cell differentiation#GO:0030154;myoblast fusion#GO:0007520;cellular process#GO:0009987;muscle cell differentiation#GO:0042692 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000021533.5|UniProtKB=F6WDS2 F6WDS2 FOXA3 PTHR11829:SF201 FORKHEAD BOX PROTEIN HEPATOCYTE NUCLEAR FACTOR 3-GAMMA transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000025297.3|UniProtKB=A0A5F8GFU2 A0A5F8GFU2 LOC100015220 PTHR11407:SF28 LYSOZYME C LYSOZYME C catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;lysozyme activity#GO:0003796 response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;defense response to Gram-negative bacterium#GO:0050829;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000045811.1|UniProtKB=A0A5F8HAH8 A0A5F8HAH8 PTHR43544:SF38 SHORT-CHAIN DEHYDROGENASE/REDUCTASE C-FACTOR-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000018063.4|UniProtKB=F7G4E8 F7G4E8 MRPL51 PTHR13409:SF0 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L51 LARGE RIBOSOMAL SUBUNIT PROTEIN ML51 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000015977.5|UniProtKB=F6QKN2 F6QKN2 TRIM39 PTHR24103:SF707 E3 UBIQUITIN-PROTEIN LIGASE TRIM RING-TYPE E3 UBIQUITIN TRANSFERASE catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 defense response#GO:0006952;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological regulation#GO:0065007;defense response to other organism#GO:0098542;immune system process#GO:0002376;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000038431.1|UniProtKB=A0A5F8GMW2 A0A5F8GMW2 LOC103104163 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010647.3|UniProtKB=F7D4I5 F7D4I5 FGFR1 PTHR24416:SF131 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;kinase activity#GO:0016301;transferase activity#GO:0016740;fibroblast growth factor binding#GO:0017134;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell differentiation#GO:0045597;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of developmental process#GO:0051094;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;response to fibroblast growth factor#GO:0071774;positive regulation of MAPK cascade#GO:0043410;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636;Angiogenesis#P00005>FGFR-1#P00186 MONDO|Ensembl=ENSMODG00000029447.2|UniProtKB=K7E0F1 K7E0F1 FAM216A PTHR16476:SF1 FAMILY WITH SEQUENCE SIMILARITY 216 MEMBER A PROTEIN FAM216A MONDO|Ensembl=ENSMODG00000014295.5|UniProtKB=F6WJR0 F6WJR0 BRD2 PTHR22880:SF240 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN-CONTAINING PROTEIN 2 histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000014296.4|UniProtKB=F6WJN9 F6WJN9 TPO PTHR11475:SF60 OXIDASE/PEROXIDASE THYROID PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209 metabolic process#GO:0008152;regulation of biological quality#GO:0065008;phenol-containing compound metabolic process#GO:0018958;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;modified amino acid metabolic process#GO:0006575;biological regulation#GO:0065007;hormone metabolic process#GO:0042445 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000040294.1|UniProtKB=A0A5F8GQK6 A0A5F8GQK6 PTHR21324:SF10 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED DNA DAMAGE-REGULATED AUTOPHAGY MODULATOR PROTEIN 2 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of autophagy#GO:0010506;homeostatic process#GO:0042592;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;anatomical structure homeostasis#GO:0060249;multicellular organismal-level homeostasis#GO:0048871;regulation of catabolic process#GO:0009894;tissue homeostasis#GO:0001894;retina homeostasis#GO:0001895 lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000011920.4|UniProtKB=F7DZX4 F7DZX4 WTIP PTHR24219:SF6 LIM DOMAIN-CONTAINING PROTEIN JUB WILMS TUMOR PROTEIN 1-INTERACTING PROTEIN transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of response to stimulus#GO:0048583;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;regulation of cell communication#GO:0010646;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;negative regulation of signal transduction#GO:0009968;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of hippo signaling#GO:0035330;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;miRNA-mediated post-transcriptional gene silencing#GO:0035195;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of hippo signaling#GO:0035331;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of translation#GO:0017148 intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;adherens junction#GO:0005912;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;cell-cell junction#GO:0005911 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000024255.1|UniProtKB=F6ZUR2 F6ZUR2 FANCD2OS PTHR31036:SF0 FANCD2 OPPOSITE STRAND PROTEIN FANCD2 OPPOSITE STRAND PROTEIN regulation of steroid biosynthetic process#GO:0050810;regulation of cellular process#GO:0050794;regulation of lipid biosynthetic process#GO:0046890;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of lipid metabolic process#GO:0019216 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000041743.1|UniProtKB=A0A5F8G6M3 A0A5F8G6M3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008090.4|UniProtKB=F7GFU8 F7GFU8 KIAA0586 PTHR15721:SF2 KIAA0586 PROTEIN PROTEIN TALPID3 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000006491.3|UniProtKB=F7F2H1 F7F2H1 LRRC8A PTHR48051:SF3 FAMILY NOT NAMED VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8E cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000024733.1|UniProtKB=F7DXU6 F7DXU6 CALML3 PTHR23050:SF552 CALCIUM BINDING PROTEIN AT16150P-RELATED metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;molecular function regulator activity#GO:0098772 microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;T cell activation#P00053>Calmodulin#P01305;B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 MONDO|Ensembl=ENSMODG00000003518.2|UniProtKB=F7C7W0 F7C7W0 C18orf32 PTHR13456:SF0 UPF0729 PROTEIN C18ORF32 UPF0729 PROTEIN C18ORF32 MONDO|Ensembl=ENSMODG00000015863.4|UniProtKB=A0A5F8GPP1 A0A5F8GPP1 FOXP2 PTHR45796:SF1 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P2 sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;muscle organ development#GO:0007517;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;skeletal muscle tissue development#GO:0007519;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;muscle tissue development#GO:0060537;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000007186.4|UniProtKB=A0A5F8H640 A0A5F8H640 DNAH3 PTHR10676:SF405 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 3 binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;microtubule motor activity#GO:0003777;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 spermatid differentiation#GO:0048515;cilium or flagellum-dependent cell motility#GO:0001539;inner dynein arm assembly#GO:0036159;cilium movement#GO:0003341;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;sperm motility#GO:0097722;protein-containing complex assembly#GO:0065003;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle assembly#GO:0070925;spermatid development#GO:0007286;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036 cytoskeleton#GO:0005856;inner dynein arm#GO:0036156;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cilium#GO:0005929;9+2 motile cilium#GO:0097729;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axonemal dynein complex#GO:0005858;dynein complex#GO:0030286;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 MONDO|Ensembl=ENSMODG00000037945.1|UniProtKB=A0A5F8G9J1 A0A5F8G9J1 HES7 PTHR10985:SF84 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-7 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;anterior/posterior pattern specification#GO:0009952;multicellular organism development#GO:0007275;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000015689.4|UniProtKB=F7E0U4 F7E0U4 VEPH1 PTHR21630:SF10 VEPH-A/MELTED VENTRICULAR ZONE-EXPRESSED PH DOMAIN-CONTAINING PROTEIN HOMOLOG 1 phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;anion binding#GO:0043168;binding#GO:0005488;phospholipid binding#GO:0005543;small molecule binding#GO:0036094;ion binding#GO:0043167 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000005066.4|UniProtKB=F7ASI8 F7ASI8 ESF1 PTHR12202:SF0 ESF1 HOMOLOG ESF1 HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 MONDO|Ensembl=ENSMODG00000016039.5|UniProtKB=A0A5F8G2Q3 A0A5F8G2Q3 CNNM3 PTHR12064:SF27 METAL TRANSPORTER CNNM METAL TRANSPORTER CNNM3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic ion homeostasis#GO:0050801;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000006322.2|UniProtKB=A0A5F8H8J4 A0A5F8H8J4 PTHR11426:SF263 HISTONE H3 HISTONE H3.X-RELATED mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic metaphase chromosome alignment#GO:0007080;protein-containing complex assembly#GO:0065003;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle fission#GO:0048285;localization#GO:0051179;kinetochore organization#GO:0051383;kinetochore assembly#GO:0051382;nuclear division#GO:0000280;organelle localization#GO:0051640;organelle assembly#GO:0070925;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000013663.4|UniProtKB=F6TXX4 F6TXX4 HSPB1 PTHR45640:SF7 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN BETA-1 response to stimulus#GO:0050896;protein folding#GO:0006457;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;protein metabolic process#GO:0019538;protein refolding#GO:0042026;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;response to heat#GO:0009408;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 p38 MAPK pathway#P05918>HSP27#P06016;VEGF signaling pathway#P00056>HSP27#P01412;CCKR signaling map#P06959>HSP27#P07154;Angiogenesis#P00005>HSP27#P00231 MONDO|Ensembl=ENSMODG00000040977.1|UniProtKB=F6V7F0 F6V7F0 monDomV1R1260 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013485.4|UniProtKB=A0A5F8GR65 A0A5F8GR65 CPNE2 PTHR10857:SF3 COPINE COPINE-2 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 cellular response to chemical stimulus#GO:0070887;response to metal ion#GO:0010038;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to chemical#GO:0042221;response to calcium ion#GO:0051592;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000000204.4|UniProtKB=F6TF37 F6TF37 DENND6A PTHR13677:SF1 LD41638P PROTEIN DENND6A guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell adhesion#GO:0045785;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of cell-cell adhesion#GO:0022409 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;recycling endosome#GO:0055037 MONDO|Ensembl=ENSMODG00000046054.1|UniProtKB=A0A5F8G4K5 A0A5F8G4K5 CDCA5 PTHR31092:SF2 SORORIN SORORIN double-strand break repair#GO:0006302;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;mitotic sister chromatid cohesion#GO:0007064;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;sister chromatid cohesion#GO:0007062;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cell cycle#GO:0007049 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000006619.3|UniProtKB=A0A5F8H624 A0A5F8H624 ODAD3 PTHR46518:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 151 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 3 plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cilium movement#GO:0003341;organelle assembly#GO:0070925;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cilium assembly#GO:0060271;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030 plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815 MONDO|Ensembl=ENSMODG00000006295.3|UniProtKB=F7BS13 F7BS13 LOC130456177 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014847.4|UniProtKB=F7BZ37 F7BZ37 MMD PTHR20855:SF26 ADIPOR/PROGESTIN RECEPTOR-RELATED MONOCYTE TO MACROPHAGE DIFFERENTIATION FACTOR G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021272.3|UniProtKB=F6T2I4 F6T2I4 SERP1 PTHR15601:SF14 STRESS ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN SERP1/RAMP4 STRESS-ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN 1 endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000041581.1|UniProtKB=A0A5F8HLA6 A0A5F8HLA6 PTHR48068:SF4 TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 9 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367 nuclear DNA-directed RNA polymerase complex#GO:0055029;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;SAGA-type complex#GO:0070461;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;peptidase complex#GO:1905368;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;SAGA complex#GO:0000124;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 MONDO|Ensembl=ENSMODG00000028306.2|UniProtKB=A0A5F8GE84 A0A5F8GE84 DPF3 PTHR23057:SF4 JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1 ZINC FINGER PROTEIN DPF3 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000006287.4|UniProtKB=F7CAF6 F7CAF6 SMARCA4 PTHR10799:SF76 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 4 catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676 heterochromatin formation#GO:0031507;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009;DNA helicase#PC00011 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000017285.4|UniProtKB=A0A5F8GPI2 A0A5F8GPI2 TXLNB PTHR16127:SF10 TAXILIN BETA-TAXILIN membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000038448.1|UniProtKB=A0A5F8GY45 A0A5F8GY45 PTHR16277:SF6 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 CELL DIVISION CYCLE-ASSOCIATED PROTEIN 4 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000051437.1|UniProtKB=A0A5F8H3N9 A0A5F8H3N9 HDGF PTHR12550:SF41 HEPATOMA-DERIVED GROWTH FACTOR-RELATED HEPATOMA-DERIVED GROWTH FACTOR cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000050607.1|UniProtKB=A0A5F8H2Z0 A0A5F8H2Z0 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000006822.4|UniProtKB=F6PGD9 F6PGD9 BEST2 PTHR10736:SF1 BESTROPHIN BESTROPHIN-2A monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000006919.4|UniProtKB=F6PS44 F6PS44 FZR1 PTHR19918:SF1 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED FIZZY-RELATED PROTEIN HOMOLOG enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;enzyme activator activity#GO:0008047;binding#GO:0005488 positive regulation of metabolic process#GO:0009893;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;metabolic process#GO:0008152;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;macromolecule catabolic process#GO:0009057;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;proteasomal protein catabolic process#GO:0010498;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;protein metabolic process#GO:0019538;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522 protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000017659.4|UniProtKB=F6YJW7 F6YJW7 PPIE PTHR11071:SF593 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE E catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000050378.1|UniProtKB=F7CWY8 F7CWY8 LOC100618734 PTHR26453:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G7 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015602.4|UniProtKB=F6Z665 F6Z665 CLN3 PTHR10981:SF0 BATTENIN BATTENIN vesicle-mediated transport#GO:0016192;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;microtubule-based process#GO:0007017;Golgi vesicle transport#GO:0048193;amino acid transport#GO:0006865;chemical homeostasis#GO:0048878;endocytosis#GO:0006897;establishment of organelle localization#GO:0051656;cytosolic transport#GO:0016482;intracellular monoatomic ion homeostasis#GO:0006873;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;post-Golgi vesicle-mediated transport#GO:0006892;lysosomal transport#GO:0007041;microtubule-based transport#GO:0099111;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;vesicle localization#GO:0051648;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;receptor-mediated endocytosis#GO:0006898;vesicle cytoskeletal trafficking#GO:0099518;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;vacuolar transport#GO:0007034;microtubule-based movement#GO:0007018;homeostatic process#GO:0042592;Golgi to vacuole transport#GO:0006896;localization#GO:0051179;organelle localization#GO:0051640;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453 Golgi apparatus#GO:0005794;lytic vacuole#GO:0000323;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000017334.3|UniProtKB=F6WVR9 F6WVR9 PTHR10210:SF123 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086 transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000045163.1|UniProtKB=A0A5F8GYE8 A0A5F8GYE8 SNAI1 PTHR24388:SF37 ZINC FINGER PROTEIN SNAIL FAMILY TRANSCRIPTIONAL REPRESSOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015982.4|UniProtKB=F7EZL7 F7EZL7 KLF7 PTHR23235:SF77 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 7 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000012254.6|UniProtKB=F6YGU2 F6YGU2 CUX2 PTHR14043:SF5 CCAAT DISPLACEMENT PROTEIN-RELATED HOMEOBOX PROTEIN CUT-LIKE 2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000006947.3|UniProtKB=F6RG00 F6RG00 HINT2 PTHR23089:SF18 HISTIDINE TRIAD HIT PROTEIN ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT2 catalytic activity#GO:0003824;hydrolase activity#GO:0016787 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 nucleotide phosphatase#PC00173 MONDO|Ensembl=ENSMODG00000000471.4|UniProtKB=F6URH4 F6URH4 CCDC149 PTHR21682:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 149 COILED-COIL DOMAIN-CONTAINING PROTEIN 149 MONDO|Ensembl=ENSMODG00000045603.1|UniProtKB=A0A5F8GAY1 A0A5F8GAY1 PTHR23430:SF56 HISTONE H2A HISTONE H2A TYPE 1-D structural molecule activity#GO:0005198 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000006183.3|UniProtKB=F7B4T6 F7B4T6 METTL21C PTHR14614:SF13 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN-LYSINE METHYLTRANSFERASE METTL21C lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000011980.3|UniProtKB=F7B9J9 F7B9J9 GPI PTHR11469:SF1 GLUCOSE-6-PHOSPHATE ISOMERASE GLUCOSE-6-PHOSPHATE ISOMERASE catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;intramolecular oxidoreductase activity#GO:0016860;carbohydrate binding#GO:0030246;monosaccharide binding#GO:0048029;isomerase activity#GO:0016853;small molecule binding#GO:0036094;binding#GO:0005488 purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ADP catabolic process#GO:0046032;carbohydrate biosynthetic process#GO:0016051;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;pyruvate metabolic process#GO:0006090;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;nucleoside phosphate catabolic process#GO:1901292;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;gluconeogenesis#GO:0006094;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;ribonucleoside diphosphate metabolic process#GO:0009185;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide catabolic process#GO:0009166;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;catabolic process#GO:0009056;glucose 6-phosphate metabolic process#GO:0051156;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleoside diphosphate catabolic process#GO:0009134;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;isomerase#PC00135 Pentose phosphate pathway#P02762>Glucose-P-Isomerase#P03080;Glycolysis#P00024>Phosphoglucose isomerase#P00674 MONDO|Ensembl=ENSMODG00000002720.4|UniProtKB=F6Z7L0 F6Z7L0 PAX5 PTHR45636:SF20 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000014400.3|UniProtKB=F6SRE9 F6SRE9 PTHR10824:SF1 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COENZYME A AMINO ACID N-ACYLTRANSFERASE 1-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;deacylase activity#GO:0160215;hydrolase activity, acting on ester bonds#GO:0016788;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyl-CoA hydrolase activity#GO:0016289;fatty acyl-CoA hydrolase activity#GO:0047617;acyltransferase activity#GO:0016746;thiolester hydrolase activity#GO:0016790;hydrolase activity#GO:0016787 nucleobase-containing compound metabolic process#GO:0006139;steroid metabolic process#GO:0008202;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;oxoacid metabolic process#GO:0043436 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;cytosol#GO:0005829;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 esterase#PC00097 MONDO|Ensembl=ENSMODG00000025459.3|UniProtKB=F6RK52 F6RK52 CLEC2L PTHR47498:SF1 C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER L C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER L MONDO|Ensembl=ENSMODG00000014539.4|UniProtKB=F6WN73 F6WN73 PTHR24221:SF237 ATP-BINDING CASSETTE SUB-FAMILY B ANTIGEN PEPTIDE TRANSPORTER 2 ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000048141.1|UniProtKB=A0A5F8G8M3 A0A5F8G8M3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000020099.4|UniProtKB=F7ESB2 F7ESB2 ARSK PTHR46615:SF1 ARYLSULFATASE K ARYLSULFATASE K catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 MONDO|Ensembl=ENSMODG00000016216.4|UniProtKB=A0A5F8GKY8 A0A5F8GKY8 HNF4A PTHR24083:SF41 NUCLEAR HORMONE RECEPTOR HEPATOCYTE NUCLEAR FACTOR 4-ALPHA molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000014610.4|UniProtKB=F6ZE34 F6ZE34 PGLYRP2 PTHR11022:SF66 PEPTIDOGLYCAN RECOGNITION PROTEIN N-ACETYLMURAMOYL-L-ALANINE AMIDASE N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;peptidoglycan muralytic activity#GO:0061783;molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;pattern recognition receptor activity#GO:0038187;catalytic activity#GO:0003824;signaling receptor activity#GO:0038023;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 response to external stimulus#GO:0009605;defense response#GO:0006952;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to Gram-positive bacterium#GO:0050830 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000021460.4|UniProtKB=F7GDU6 F7GDU6 ZBTB14 PTHR24399:SF5 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 14 DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000006731.4|UniProtKB=F7CX31 F7CX31 IER5L PTHR15895:SF14 IMMEDIATE EARLY RESPONSE GENE IMMEDIATE EARLY RESPONSE GENE 5-LIKE PROTEIN MONDO|Ensembl=ENSMODG00000016368.3|UniProtKB=A0A5F8HGT4 A0A5F8HGT4 GPR22 PTHR24241:SF1 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 22 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002883.4|UniProtKB=K7E250 K7E250 INTS7 PTHR13322:SF2 C1ORF73 PROTEIN INTEGRATOR COMPLEX SUBUNIT 7 snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;snRNA 3'-end processing#GO:0034472;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;catabolic process#GO:0009056;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound catabolic process#GO:0034655 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;integrator complex#GO:0032039;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000016516.4|UniProtKB=H9H6X8 H9H6X8 PDK4 PTHR11947:SF22 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 4, MITOCHONDRIAL kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;cellular response to insulin stimulus#GO:0032869;regulation of carbohydrate metabolic process#GO:0006109;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of lipid metabolic process#GO:0019216;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;cellular response to chemical stimulus#GO:0070887 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000011394.4|UniProtKB=A0A5F8GGI0 A0A5F8GGI0 ADD2 PTHR10672:SF6 ADDUCIN BETA-ADDUCIN binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of protein depolymerization#GO:1901879;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of actin filament depolymerization#GO:0030834;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of protein-containing complex assembly#GO:0031333;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008 intracellular anatomical structure#GO:0005622;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000011347.5|UniProtKB=F7D3I7 F7D3I7 EFTUD2 PTHR42908:SF6 TRANSLATION ELONGATION FACTOR-RELATED 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleic acid binding#GO:0003676;binding#GO:0005488;GTPase activity#GO:0003924;snRNA binding#GO:0017069;hydrolase activity#GO:0016787;RNA binding#GO:0003723;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;translation factor activity#GO:0180051;hydrolase activity, acting on acid anhydrides#GO:0016817;translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;translational elongation#GO:0006414;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;protein biosynthetic process#GO:0160307;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;translation#GO:0006412;RNA splicing, via transesterification reactions#GO:0000375 protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;cytoplasm#GO:0005737;cytosol#GO:0005829;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 translation elongation factor#PC00222 MONDO|Ensembl=ENSMODG00000001094.4|UniProtKB=F7DPP9 F7DPP9 FMOD PTHR45712:SF4 AGAP008170-PA FIBROMODULIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000024599.1|UniProtKB=F7DGX0 F7DGX0 RAP2B PTHR24070:SF194 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-2B ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 regulation of cell migration#GO:0030334;negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906 MONDO|Ensembl=ENSMODG00000001122.4|UniProtKB=A0A5F8GRU2 A0A5F8GRU2 RBFOX2 PTHR15597:SF31 ATAXIN 2-BINDING PROTEIN 1-RELATED RNA BINDING PROTEIN FOX-1 HOMOLOG 2 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;nervous system development#GO:0007399;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 RNA splicing factor#PC00148;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000025135.2|UniProtKB=F7D612 F7D612 PTHR22798:SF0 MCT-1 PROTEIN MALIGNANT T-CELL-AMPLIFIED SEQUENCE 1 translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183;translation#GO:0006412;translational initiation#GO:0006413;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 translation initiation factor#PC00224 MONDO|Ensembl=ENSMODG00000017558.4|UniProtKB=F7BSS5 F7BSS5 CCN2 PTHR11348:SF7 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 2 carbohydrate derivative binding#GO:0097367;cell adhesion molecule binding#GO:0050839;heparin binding#GO:0008201;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102;glycosaminoglycan binding#GO:0005539;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 signaling#GO:0023052;regulation of developmental process#GO:0050793;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cell adhesion#GO:0007155;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 growth factor#PC00112;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000013876.4|UniProtKB=F6W973 F6W973 CREB3L2 PTHR46004:SF2 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Transcription regulation by bZIP transcription factor#P00055>CREB#P01383 MONDO|Ensembl=ENSMODG00000048532.1|UniProtKB=A0A5F8H8G5 A0A5F8H8G5 PTHR10044:SF79 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;enzyme regulator activity#GO:0030234 positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;positive regulation of protein metabolic process#GO:0051247;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of protein modification process#GO:0031399;regulation of apoptotic process#GO:0042981;regulation of protein ubiquitination#GO:0031396;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;positive regulation of protein ubiquitination#GO:0031398;negative regulation of apoptotic process#GO:0043066;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 Apoptosis signaling pathway#P00006>c-IAP1,2#P00264;CCKR signaling map#P06959>BIRC2#G07278 MONDO|Ensembl=ENSMODG00000017455.4|UniProtKB=F6Z5R3 F6Z5R3 HDAC1 PTHR10625:SF49 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 1 catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;heterochromatin organization#GO:0070828 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;chromatin#GO:0000785 Wnt signaling pathway#P00057>Histone deacetylase#P01472;p53 pathway#P00059>HDAC1#P04612 MONDO|Ensembl=ENSMODG00000017336.3|UniProtKB=F6WVR1 F6WVR1 GATAD2B PTHR13455:SF4 TRANSCRIPTIONAL REPRESSOR P66-RELATED TRANSCRIPTIONAL REPRESSOR P66-BETA DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000003464.4|UniProtKB=F7DCB6 F7DCB6 CTIF PTHR23254:SF16 EIF4G DOMAIN PROTEIN CBP80_20-DEPENDENT TRANSLATION INITIATION FACTOR translation regulator activity#GO:0045182 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of translational initiation#GO:0006446 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000002800.4|UniProtKB=F7EJJ9 F7EJJ9 HGS PTHR46275:SF1 HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 endocytosis#GO:0006897;endocytic recycling#GO:0032456;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;receptor internalization#GO:0031623;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport to the plasma membrane#GO:0098876;receptor-mediated endocytosis#GO:0006898;endosomal transport#GO:0016197;import into cell#GO:0098657;establishment of localization#GO:0051234 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 MONDO|Ensembl=ENSMODG00000039309.1|UniProtKB=A0A5F8HEY2 A0A5F8HEY2 CXCL11 PTHR12015:SF191 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 11 cytokine#PC00083 MONDO|Ensembl=ENSMODG00000018499.2|UniProtKB=F7BR25 F7BR25 UCN3 PTHR17575:SF1 UROCORTIN-2 AND 3 UROCORTIN-3 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;neuropeptide receptor binding#GO:0071855;binding#GO:0005488;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;response to nutrient levels#GO:0031667;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to nutrient levels#GO:0031669 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000000090.4|UniProtKB=F6Q8S7 F6Q8S7 ASMTL PTHR43213:SF5 BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED BIFUNCTIONAL DTTP_UTP PYROPHOSPHATASE_METHYLTRANSFERASE PROTEIN-RELATED nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 MONDO|Ensembl=ENSMODG00000016552.4|UniProtKB=H9H6Z0 H9H6Z0 PTHR17537:SF3 TRANSDUCER OF ERBB2 TOB PROTEIN TOB2 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000039830.1|UniProtKB=A0A5F8HG54 A0A5F8HG54 PTHR12146:SF25 40S RIBOSOMAL PROTEIN S10 PLECTIN_ES10 N-TERMINAL DOMAIN-CONTAINING PROTEIN structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000014233.4|UniProtKB=A0A5F8GEZ9 A0A5F8GEZ9 PTHR22444:SF1 GLUTAMATE-RICH PROTEIN 1 GLUTAMATE-RICH PROTEIN 1 MONDO|Ensembl=ENSMODG00000043549.1|UniProtKB=A0A5F8HHC7 A0A5F8HHC7 PTHR48160:SF1 LARGE RIBOSOMAL SUBUNIT PROTEIN EL43 LARGE RIBOSOMAL SUBUNIT PROTEIN EL43 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000020631.4|UniProtKB=F7EN68 F7EN68 SLAIN2 PTHR22406:SF4 NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM SLAIN MOTIF-CONTAINING PROTEIN 2 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;positive regulation of cellular component biogenesis#GO:0044089;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of organelle organization#GO:0010638;regulation of microtubule polymerization#GO:0031113;positive regulation of cellular component organization#GO:0051130;regulation of cellular component organization#GO:0051128;cytoplasmic microtubule organization#GO:0031122;regulation of cellular component biogenesis#GO:0044087;microtubule nucleation#GO:0007020;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;regulation of organelle organization#GO:0033043;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule polymerization#GO:0046785;positive regulation of protein polymerization#GO:0032273;biological regulation#GO:0065007;microtubule polymerization or depolymerization#GO:0031109;positive regulation of cellular process#GO:0048522;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;regulation of microtubule-based process#GO:0032886;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;regulation of supramolecular fiber organization#GO:1902903 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;microtubule end#GO:1990752;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000015075.4|UniProtKB=F7FH52 F7FH52 AZI2 PTHR14432:SF6 PROSAPIP2 PROTEIN/5-AZACYTIDINE INDUCED GENE 2 5-AZACYTIDINE-INDUCED PROTEIN 2 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000006820.5|UniProtKB=F7BVA0 F7BVA0 RBM25 PTHR18806:SF4 RBM25 PROTEIN RNA-BINDING PROTEIN 25 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024 MONDO|Ensembl=ENSMODG00000002937.4|UniProtKB=F6PM66 F6PM66 PTHR14482:SF0 CHROMOSOME 12 ORF 43 HOMOLOG PROTEIN CUSTOS anatomical structure development#GO:0048856;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of biological process#GO:0048519;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;anatomical structure formation involved in morphogenesis#GO:0048646;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 MONDO|Ensembl=ENSMODG00000021459.5|UniProtKB=A0A5F8G8V8 A0A5F8G8V8 EPB41L3 PTHR23280:SF20 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 3 plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 MONDO|Ensembl=ENSMODG00000037271.1|UniProtKB=A0A5F8GCZ3 A0A5F8GCZ3 VN2R516 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002994.4|UniProtKB=F6Q4B0 F6Q4B0 PTHR28618:SF1 CENTROSOMAL PROTEIN POC5 CENTROSOMAL PROTEIN POC5 MONDO|Ensembl=ENSMODG00000019596.3|UniProtKB=A0A5S8BEX8 A0A5S8BEX8 PTHR43128:SF10 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A CHAIN oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;generation of precursor metabolites and energy#GO:0006091;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;energy derivation by oxidation of organic compounds#GO:0015980 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000010056.4|UniProtKB=A0A5F8GQ68 A0A5F8GQ68 DGCR2 PTHR15256:SF6 INTEGRAL MEMBRANE PROTEIN DGCR2/IDD INTEGRAL MEMBRANE PROTEIN DGCR2_IDD cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000018549.4|UniProtKB=F7GCU7 F7GCU7 CLDN18 PTHR12002:SF9 CLAUDIN CLAUDIN-18 cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840 anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;apical junction complex#GO:0043296;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 cell junction protein#PC00070;tight junction#PC00214 MONDO|Ensembl=ENSMODG00000044041.1|UniProtKB=A0A5F8HJX2 A0A5F8HJX2 PTHR40389:SF3 ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED IGE-BINDING PROTEIN MONDO|Ensembl=ENSMODG00000005172.4|UniProtKB=F7E7I3 F7E7I3 LOC103099712 PTHR23120:SF6 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT FAMILY MEMBER 5 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000013774.4|UniProtKB=F6TS07 F6TS07 CEP170B PTHR15715:SF18 CENTROSOMAL PROTEIN OF 170 KDA CENTROSOMAL PROTEIN OF 170 KDA PROTEIN B protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule anchoring at microtubule organizing center#GO:0072393;microtubule anchoring#GO:0034453;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000001430.4|UniProtKB=F7BCI5 F7BCI5 ADCY8 PTHR45627:SF1 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 8 cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829 cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;nucleoside phosphate biosynthetic process#GO:1901293;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;G protein-coupled receptor signaling pathway#GO:0007186;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 adenylate cyclase#PC00043 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 MONDO|Ensembl=ENSMODG00000002497.4|UniProtKB=F7B9S5 F7B9S5 TGFBRAP1 PTHR12894:SF51 CNH DOMAIN CONTAINING TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1 vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;vesicle fusion#GO:0006906;membrane organization#GO:0061024;cellular component organization#GO:0016043;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;vesicle organization#GO:0016050;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 MONDO|Ensembl=ENSMODG00000029644.1|UniProtKB=K7E2T3 K7E2T3 LOC107650305 PTHR12081:SF50 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000015605.4|UniProtKB=A0A5F8GJ00 A0A5F8GJ00 FN1 PTHR46708:SF8 TENASCIN FIBRONECTIN cell adhesion molecule binding#GO:0050839;carbohydrate derivative binding#GO:0097367;signaling receptor binding#GO:0005102;binding#GO:0005488;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 animal gross anatomical part developmental process#GO:0160108;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;anatomical structure development#GO:0048856;system development#GO:0048731;cell-substrate junction assembly#GO:0007044;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;circulatory system development#GO:0072359;cell junction organization#GO:0034330;cell-substrate junction organization#GO:0150115;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;heart development#GO:0007507;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;nervous system development#GO:0007399 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Fibronectin#P00939 MONDO|Ensembl=ENSMODG00000004924.3|UniProtKB=F7BGV2 F7BGV2 BTBD3 PTHR45774:SF2 BTB/POZ DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN 3 developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;brain development#GO:0007420;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;anatomical structure development#GO:0048856;system development#GO:0048731;dendrite morphogenesis#GO:0048813;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;head development#GO:0060322;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;dendrite development#GO:0016358;neuron development#GO:0048666;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;forebrain development#GO:0030900;cell development#GO:0048468 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000043645.1|UniProtKB=A0A5F8GZA6 A0A5F8GZA6 DNAJB9 PTHR44360:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 intracellular organelle lumen#GO:0070013;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000043816.1|UniProtKB=A0A5F8H130 A0A5F8H130 PTHR33426:SF46 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000038088.1|UniProtKB=A0A5F8HF30 A0A5F8HF30 PTHR38505:SF1 HYPOTHETICAL PROTEIN LOC100362176 SIMILAR TO HUMAN CHROMOSOME 3 OPEN READING FRAME 80 MONDO|Ensembl=ENSMODG00000010659.4|UniProtKB=F7D428 F7D428 RFT1 PTHR13117:SF5 ENDOPLASMIC RETICULUM MULTISPAN TRANSMEMBRANE PROTEIN-RELATED MAN(5)GLCNAC(2)-PP-DOLICHOL TRANSLOCATION PROTEIN RFT1 lipid localization#GO:0010876;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;regulation of biological quality#GO:0065008;regulation of membrane lipid distribution#GO:0097035;cellular component organization#GO:0016043;macromolecule localization#GO:0033036;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;lipid transport#GO:0006869;lipid translocation#GO:0034204;membrane organization#GO:0061024;biological regulation#GO:0065007 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000011809.3|UniProtKB=F7CBC3 F7CBC3 LSM12 PTHR13542:SF0 LSM12 HOMOLOG PROTEIN LSM12 MONDO|Ensembl=ENSMODG00000013160.4|UniProtKB=A0A5F8G6M4 A0A5F8G6M4 TRIM9 PTHR24099:SF13 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM9 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000013842.4|UniProtKB=A0A5F8HGL0 A0A5F8HGL0 AFF4 PTHR10528:SF15 AF4/FMR2 FAMILY MEMBER AF4_FMR2 FAMILY MEMBER 4 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;DNA-templated transcription elongation#GO:0006354;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;gene expression#GO:0010467;multicellular organismal process#GO:0032501;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;system process#GO:0003008;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleic acid biosynthetic process#GO:0141187;nervous system process#GO:0050877;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;RNA metabolic process#GO:0016070 intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000015536.4|UniProtKB=F6VH37 F6VH37 PTHR11551:SF4 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 5 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000016821.2|UniProtKB=F7FIH8 F7FIH8 NAXE PTHR13232:SF11 NAD(P)H-HYDRATE EPIMERASE NAD(P)H-HYDRATE EPIMERASE isomerase activity#GO:0016853;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;epimerase/racemase#PC00096 MONDO|Ensembl=ENSMODG00000016603.3|UniProtKB=F6ZCX3 F6ZCX3 TUBB1 PTHR11588:SF112 TUBULIN TUBULIN BETA-1 CHAIN GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 cytoskeletal protein#PC00085;tubulin#PC00228 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 MONDO|Ensembl=ENSMODG00000004769.4|UniProtKB=A0A5F8GIR8 A0A5F8GIR8 CPPED1 PTHR43143:SF1 METALLOPHOSPHOESTERASE, CALCINEURIN SUPERFAMILY SERINE_THREONINE-PROTEIN PHOSPHATASE CPPED1 protein modifying enzyme#PC00260;protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000040979.1|UniProtKB=A0A5F8H420 A0A5F8H420 SNX12 PTHR45963:SF3 RE52028P SORTING NEXIN-12 phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981 vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization within membrane#GO:0051668;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147 early endosome membrane#GO:0031901;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000020479.4|UniProtKB=F7FIW9 F7FIW9 LIN7A PTHR14063:SF4 PROTEIN LIN-7 HOMOLOG PROTEIN LIN-7 HOMOLOG A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of growth#GO:0040008;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;signal release#GO:0023061;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;regulation of cell junction assembly#GO:1901888;localization#GO:0051179;cell communication#GO:0007154;regulation of synapse structure or activity#GO:0050803;secretion#GO:0046903;vesicle localization#GO:0051648;regulation of synapse assembly#GO:0051963;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;transport#GO:0006810;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;establishment of organelle localization#GO:0051656;export from cell#GO:0140352;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of synapse organization#GO:0050807;cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of biological quality#GO:0065008;synaptic vesicle transport#GO:0048489;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836 anchoring junction#GO:0070161;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;basal part of cell#GO:0045178;adherens junction#GO:0005912;cell junction#GO:0030054;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;cell-cell junction#GO:0005911;membrane#GO:0016020 cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000005254.4|UniProtKB=F7GH19 F7GH19 DNAJB6 PTHR43948:SF6 DNAJ HOMOLOG SUBFAMILY B DNAJ HOMOLOG SUBFAMILY B MEMBER 6 protein binding#GO:0005515;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000044617.1|UniProtKB=A0A5F8G6Z9 A0A5F8G6Z9 ZNF467 PTHR24409:SF450 ZINC FINGER PROTEIN 142 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 17 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000051396.1|UniProtKB=A0A5F8G454 A0A5F8G454 LOC100617161 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014742.4|UniProtKB=A0A5F8HDW2 A0A5F8HDW2 CNP PTHR10156:SF0 2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE 2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;cyclic-nucleotide phosphodiesterase activity#GO:0004112 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000028090.2|UniProtKB=K7E225 K7E225 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000018935.4|UniProtKB=F7GJP9 F7GJP9 SLC29A1 PTHR10332:SF9 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleoside transmembrane transporter activity#GO:0005337 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000007664.3|UniProtKB=F7FNR3 F7FNR3 P2RY2 PTHR24231:SF17 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 2 G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;G protein-coupled receptor binding#GO:0001664;molecular transducer activity#GO:0060089;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000013357.4|UniProtKB=F7DTX9 F7DTX9 TRAF3 PTHR10131:SF76 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 cell communication#GO:0007154;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;signal transduction#GO:0007165 membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004240.4|UniProtKB=F6UBF4 F6UBF4 TUBGCP3 PTHR19302:SF14 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 3 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 sexual reproduction#GO:0019953;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;microtubule nucleation#GO:0007020;cell cycle#GO:0007049;reproductive process#GO:0022414;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000003193.4|UniProtKB=F6VGR2 F6VGR2 PSTPIP2 PTHR23065:SF9 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROLINE-SERINE-THREONINE PHOSPHATASE-INTERACTING PROTEIN 2 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000018035.4|UniProtKB=F6ZWF9 F6ZWF9 LIN28B PTHR46109:SF3 PROTEIN LIN-28 PROTEIN LIN-28 HOMOLOG B nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;pre-miRNA processing#GO:0031054;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000046476.1|UniProtKB=A0A5F8GCB7 A0A5F8GCB7 PTHR46479:SF1 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;organelle localization#GO:0051640;transport#GO:0006810;vesicle-mediated transport#GO:0016192;lysosome localization#GO:0032418;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;BLOC-1 complex#GO:0031083;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000016102.4|UniProtKB=F7EB31 F7EB31 LRRC31 PTHR24109:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 31 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 31 MONDO|Ensembl=ENSMODG00000000768.3|UniProtKB=A0A5F8H994 A0A5F8H994 FAM50A PTHR12722:SF0 XAP-5 PROTEIN-RELATED PROTEIN FAM50A cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000001551.3|UniProtKB=F7E670 F7E670 PTHR19282:SF203 TETRASPANIN TETRASPANIN-13 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007055.4|UniProtKB=F6UF93 F6UF93 HAPLN4 PTHR22804:SF11 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 4 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;nervous system development#GO:0007399;central nervous system development#GO:0007417;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;cell junction#GO:0030054;extracellular matrix#GO:0031012;membrane#GO:0016020;external encapsulating structure#GO:0030312;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 MONDO|Ensembl=ENSMODG00000012414.3|UniProtKB=F6PMC9 F6PMC9 GTF2B PTHR11618:SF77 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION INITIATION FACTOR IIB sequence-specific DNA binding#GO:0043565;transferase activity#GO:0016740;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;acetyltransferase activity#GO:0016407;sequence-specific double-stranded DNA binding#GO:1990837;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transcription factor binding#GO:0008134;catalytic activity#GO:0003824;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;core promoter sequence-specific DNA binding#GO:0001046;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;acyltransferase activity#GO:0016746;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259 General transcription regulation#P00023>TFIIB#P00668;Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397 MONDO|Ensembl=ENSMODG00000012140.4|UniProtKB=F7DI19 F7DI19 LOC100017631 PTHR11905:SF120 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 1A-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;reproductive process#GO:0022414;reproductive structure development#GO:0048608;animal gross anatomical part developmental process#GO:0160108;proteolysis#GO:0006508;reproductive system development#GO:0061458;system development#GO:0048731;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;sex differentiation#GO:0007548;cellular process#GO:0009987;male gonad development#GO:0008584;gonad development#GO:0008406;multicellular organismal process#GO:0032501;male sex differentiation#GO:0046661;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;development of primary male sexual characteristics#GO:0046546;metabolic process#GO:0008152;animal organ development#GO:0048513;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000004364.4|UniProtKB=F6WP80 F6WP80 ARHGAP19 PTHR14963:SF7 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 19 GTPase-activating protein#PC00257;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000012653.5|UniProtKB=F6VXP8 F6VXP8 ZNF536 PTHR45925:SF2 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 536 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000019725.5|UniProtKB=F6X4V6 F6X4V6 RC3H2 PTHR13139:SF2 RING FINGER AND CCCH-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN ROQUIN-2 RNA binding#GO:0003723;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;double-stranded RNA binding#GO:0003725;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;protein modification process#GO:0036211;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-translational protein modification#GO:0043687;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;RNA catabolic process#GO:0006401;positive regulation of macromolecule metabolic process#GO:0010604;protein ubiquitination#GO:0016567;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152 ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000005637.4|UniProtKB=F7CEY5 F7CEY5 PTHR23267:SF189 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR DELTA VARIABLE 3 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000001040.4|UniProtKB=F6ZEY0 F6ZEY0 MYBPH PTHR13817:SF49 TITIN MYOSIN-BINDING PROTEIN H structural molecule activity#GO:0005198 developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;myofibril assembly#GO:0030239;anatomical structure morphogenesis#GO:0009653;muscle cell differentiation#GO:0042692;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle cell development#GO:0055001;cell development#GO:0048468;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cell differentiation#GO:0030154 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;A band#GO:0031672;contractile muscle fiber#GO:0043292;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;M band#GO:0031430;intracellular organelle#GO:0043229 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000028422.2|UniProtKB=K7E4Q8 K7E4Q8 PTHR11467:SF42 HISTONE H1 HISTONE H1.8 chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;double-stranded DNA binding#GO:0003690;nucleosome binding#GO:0031491;DNA binding#GO:0003677;chromatin DNA binding#GO:0031490 regulation of DNA recombination#GO:0000018;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;negative regulation of DNA recombination#GO:0045910;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000015743.4|UniProtKB=A0A5F8G3Z8 A0A5F8G3Z8 LEKR1 PTHR34251:SF1 LEUCINE-, GLUTAMATE- AND LYSINE-RICH PROTEIN 1 LEUCINE, GLUTAMATE AND LYSINE RICH 1 MONDO|Ensembl=ENSMODG00000015036.4|UniProtKB=A0A5F8H2K9 A0A5F8H2K9 MYO9B PTHR46184:SF2 UNCONVENTIONAL MYOSIN-IXB-LIKE PROTEIN UNCONVENTIONAL MYOSIN-IXB macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;actin filament binding#GO:0051015;anion binding#GO:0043168;small molecule binding#GO:0036094;polypeptide conformation or assembly isomerase activity#GO:0120544;ion binding#GO:0043167;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;cytoskeletal motor activity#GO:0003774;purine ribonucleotide binding#GO:0032555;ATP-dependent activity#GO:0140657;actin binding#GO:0003779;binding#GO:0005488;ATP binding#GO:0005524;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 plasma membrane bounded cell projection morphogenesis#GO:0120039;actin filament-based process#GO:0030029;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;anatomical structure development#GO:0048856;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;actin filament-based movement#GO:0030048;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030 lamellipodium#GO:0030027;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cell leading edge#GO:0031252;polymeric cytoskeletal fiber#GO:0099513;ruffle#GO:0001726;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;actin filament#GO:0005884;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000007535.4|UniProtKB=F7GB53 F7GB53 TBPL2 PTHR10126:SF37 TATA-BOX BINDING PROTEIN TATA BOX-BINDING PROTEIN-LIKE 2 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription initiation#GO:0006352;gene expression#GO:0010467;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399 MONDO|Ensembl=ENSMODG00000011311.4|UniProtKB=F6WJ64 F6WJ64 LARS2 PTHR43740:SF3 LEUCYL-TRNA SYNTHETASE LEUCINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000028627.2|UniProtKB=F6XFC6 F6XFC6 LOC107652156 PTHR24393:SF100 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 345-RELATED sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000021298.4|UniProtKB=F7G3U1 F7G3U1 PEX5L PTHR10130:SF1 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5 PEX5-RELATED PROTEIN signal sequence receptor activity#GO:0005048;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558;cellular component organization#GO:0016043;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;peroxisomal transport#GO:0043574;peroxisome organization#GO:0007031 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;peroxisome#GO:0005777;cytosol#GO:0005829;microbody#GO:0042579;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000025512.3|UniProtKB=A0A5F8GFX9 A0A5F8GFX9 CEP15 PTHR14286:SF2 GENE, 49355-RELATED CENTROSOMAL PROTEIN 15 MONDO|Ensembl=ENSMODG00000018402.4|UniProtKB=A0A5F8GW75 A0A5F8GW75 RUBCN PTHR45971:SF3 PHOX (PX) DOMAIN-CONTAINING PROTEIN RUN DOMAIN BECLIN-1-INTERACTING AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981 negative regulation of autophagy#GO:0010507;regulation of localization#GO:0032879;regulation of macroautophagy#GO:0016241;regulation of transport#GO:0051049;regulation of catabolic process#GO:0009894;regulation of autophagosome maturation#GO:1901096;regulation of endocytosis#GO:0030100;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of macroautophagy#GO:0016242;regulation of protein-containing complex disassembly#GO:0043244;regulation of metabolic process#GO:0019222;negative regulation of catabolic process#GO:0009895;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of metabolic process#GO:0009892;negative regulation of transport#GO:0051051;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000014879.3|UniProtKB=F6YKR4 F6YKR4 NKIRAS1 PTHR46152:SF1 NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 MONDO|Ensembl=ENSMODG00000007714.4|UniProtKB=A0A5F8H087 A0A5F8H087 CPA6 PTHR11705:SF18 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A6 metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000001899.4|UniProtKB=F6W1U6 F6W1U6 LOC100030124 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740 glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 MONDO|Ensembl=ENSMODG00000009645.4|UniProtKB=F6QTB4 F6QTB4 PCMTD1 PTHR11579:SF4 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;O-methyltransferase activity#GO:0008171 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 methyltransferase#PC00155;transferase#PC00220 MONDO|Ensembl=ENSMODG00000042134.1|UniProtKB=F6RPR9 F6RPR9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000019088.4|UniProtKB=F7FNC0 F7FNC0 GRSF1 PTHR13976:SF42 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED G-RICH SEQUENCE FACTOR 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000005089.4|UniProtKB=F7A3S7 F7A3S7 NR1I3 PTHR24082:SF231 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 3 sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067 negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000018792.4|UniProtKB=F6ZNQ0 F6ZNQ0 TARS2 PTHR11451:SF27 THREONINE-TRNA LIGASE THREONINE--TRNA LIGASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038 aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000018386.5|UniProtKB=A0A5F8H855 A0A5F8H855 PGM3 PTHR45955:SF5 PHOSPHOACETYLGLUCOSAMINE MUTASE PHOSPHOACETYLGLUCOSAMINE MUTASE isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868 UDP-N-acetylglucosamine biosynthetic process#GO:0006048;anatomical structure development#GO:0048856;UDP-N-acetylglucosamine metabolic process#GO:0006047;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;cell development#GO:0048468;cell differentiation#GO:0030154;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;developmental process#GO:0032502;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;cellular developmental process#GO:0048869;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;hemopoiesis#GO:0030097;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225 isomerase#PC00135;mutase#PC00160 MONDO|Ensembl=ENSMODG00000013657.3|UniProtKB=F6TXZ4 F6TXZ4 CDO1 PTHR12918:SF1 CYSTEINE DIOXYGENASE CYSTEINE DIOXYGENASE TYPE 1 dioxygenase activity#GO:0051213;metal ion binding#GO:0046872;cation binding#GO:0043169;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;iron ion binding#GO:0005506;oxidoreductase activity#GO:0016491;ferrous iron binding#GO:0008198;catalytic activity#GO:0003824 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;sulfur compound catabolic process#GO:0044273 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000013298.4|UniProtKB=F6ZJD5 F6ZJD5 TBCCD1 PTHR16052:SF4 TBCC DOMAIN-CONTAINING PROTEIN 1 TBCC DOMAIN-CONTAINING PROTEIN 1 organelle localization#GO:0051640;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;centrosome localization#GO:0051642 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000013348.4|UniProtKB=A0A5F8GNA7 A0A5F8GNA7 SEMA4D PTHR11036:SF18 SEMAPHORIN SEMAPHORIN-4D signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;taxis#GO:0042330;response to chemical#GO:0042221;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;regulation of cellular process#GO:0050794;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;chemotaxis#GO:0006935;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;axon development#GO:0061564;axon guidance#GO:0007411;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 membrane-bound signaling molecule#PC00152 Axon guidance mediated by semaphorins#P00007>Sema4D#P00329 MONDO|Ensembl=ENSMODG00000018846.4|UniProtKB=F7DWH6 F7DWH6 LOC103092765 PTHR10334:SF418 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE RICH SECRETORY PROTEIN 2 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000003041.2|UniProtKB=F6Q0F4 F6Q0F4 NPB PTHR28553:SF1 NEUROPEPTIDE B NEUROPEPTIDE B binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;feeding behavior#GO:0007631;cell communication#GO:0007154 MONDO|Ensembl=ENSMODG00000047420.1|UniProtKB=A0A5F8GD69 A0A5F8GD69 ACTG1 PTHR11937:SF575 ACTIN ACTIN, CYTOPLASMIC 2 structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Alzheimer disease-presenilin pathway#P00004>actin#P00114 MONDO|Ensembl=ENSMODG00000028617.2|UniProtKB=K7E2K5 K7E2K5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000040412.1|UniProtKB=F7FFZ0 F7FFZ0 PTHR33426:SF30 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000010236.4|UniProtKB=A0A5F8GF81 A0A5F8GF81 PORCN PTHR13906:SF12 PORCUPINE PROTEIN-SERINE O-PALMITOLEOYLTRANSFERASE PORCUPINE acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;binding#GO:0005488;transferase activity#GO:0016740;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 secretion by cell#GO:0032940;protein transport#GO:0015031;protein secretion#GO:0009306;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;signal release#GO:0023061;signaling#GO:0023052;export from cell#GO:0140352;regulation of biological process#GO:0050789;protein localization to extracellular region#GO:0071692;primary metabolic process#GO:0044238;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;lipid modification#GO:0030258;establishment of localization#GO:0051234;transport#GO:0006810;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000005422.4|UniProtKB=F7FVB4 F7FVB4 PHGDH PTHR42938:SF22 FORMATE DEHYDROGENASE 1 D-3-PHOSPHOGLYCERATE DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 oxidoreductase#PC00176;dehydrogenase#PC00092 Serine glycine biosynthesis#P02776>Phosphoglycerate dehydrogenase#P03160 MONDO|Ensembl=ENSMODG00000020804.4|UniProtKB=A0A5F8GF27 A0A5F8GF27 FUBP1 PTHR10288:SF99 KH DOMAIN CONTAINING RNA BINDING PROTEIN FAR UPSTREAM ELEMENT-BINDING PROTEIN 1 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000020450.4|UniProtKB=F7A3E5 F7A3E5 GLIPR1 PTHR10334:SF459 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLIOMA PATHOGENESIS-RELATED PROTEIN 1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000004376.4|UniProtKB=F6W8B1 F6W8B1 SLC16A6 PTHR11360:SF20 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 7 monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 MONDO|Ensembl=ENSMODG00000006572.4|UniProtKB=F7B879 F7B879 VWA1 PTHR24020:SF77 COLLAGEN ALPHA VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000008952.3|UniProtKB=F7GCP9 F7GCP9 SAE1 PTHR10953:SF162 UBIQUITIN-ACTIVATING ENZYME E1 SUMO-ACTIVATING ENZYME SUBUNIT 1 ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a protein#GO:0140096 post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein sumoylation#GO:0016925;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 MONDO|Ensembl=ENSMODG00000023616.3|UniProtKB=A0A5F8GTN2 A0A5F8GTN2 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000006192.3|UniProtKB=F6ZSW2 F6ZSW2 PTHR24399:SF80 ZINC FINGER AND BTB DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cytokine production#GO:0001817;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014154.3|UniProtKB=F6X2Z8 F6X2Z8 PTHR23149:SF9 G PATCH DOMAIN CONTAINING PROTEIN G PATCH DOMAIN-CONTAINING PROTEIN 4 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000006531.4|UniProtKB=F7CDG3 F7CDG3 AGPAT4 PTHR10983:SF8 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE DELTA acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739 transferase#PC00220;acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000008829.4|UniProtKB=F7FFG4 F7FFG4 RNF111 PTHR16200:SF4 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE ARKADIA catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000007288.3|UniProtKB=F7FCH1 F7FCH1 PTHR43128:SF10 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A CHAIN oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000020108.3|UniProtKB=F7EAG3 F7EAG3 ZDHHC5 PTHR12349:SF3 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 PALMITOYLTRANSFERASE ZDHHC5 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to external stimulus#GO:0032101;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of immune system process#GO:0002684;positive regulation of pattern recognition receptor signaling pathway#GO:0062208;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of response to external stimulus#GO:0032103;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 MONDO|Ensembl=ENSMODG00000009002.4|UniProtKB=A0A5F8H7E1 A0A5F8H7E1 NEIL1 PTHR22993:SF27 FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE ENDONUCLEASE 8-LIKE 1 endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;DNA N-glycosylase activity#GO:0019104 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA glycosylase#PC00010 MONDO|Ensembl=ENSMODG00000008379.3|UniProtKB=F7CDT3 F7CDT3 LOC100018927 PTHR24300:SF406 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2B6 catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;binding#GO:0005488;tetrapyrrole binding#GO:0046906 olefinic compound metabolic process#GO:0120254;response to xenobiotic stimulus#GO:0009410;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;xenobiotic metabolic process#GO:0006805;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular response to stimulus#GO:0051716;arachidonate metabolic process#GO:0019369;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;icosanoid metabolic process#GO:0006690;response to chemical#GO:0042221;cellular response to xenobiotic stimulus#GO:0071466;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176;oxygenase#PC00177 Bupropion degradation#P05729>Cytochrome P450 2B6#P05742 MONDO|Ensembl=ENSMODG00000050223.1|UniProtKB=A0A5F8G2P1 A0A5F8G2P1 WNT9B PTHR12027:SF84 WNT RELATED PROTEIN WNT-9B protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664 neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;cell fate commitment#GO:0045165;system development#GO:0048731;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 MONDO|Ensembl=ENSMODG00000025557.3|UniProtKB=F6UIB1 F6UIB1 PTHR47734:SF1 T-CELL IMMUNORECEPTOR WITH IG AND ITIM DOMAINS PROTEIN, TIGIT T-CELL IMMUNORECEPTOR WITH IG AND ITIM DOMAINS protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 negative regulation of cell adhesion#GO:0007162;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of immune system process#GO:0002683;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;negative regulation of cell activation#GO:0050866;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cytokine production#GO:0001819;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;negative regulation of leukocyte cell-cell adhesion#GO:1903038;negative regulation of multicellular organismal process#GO:0051241;positive regulation of biosynthetic process#GO:0009891;negative regulation of T cell activation#GO:0050868;negative regulation of cell-cell adhesion#GO:0022408;positive regulation of macromolecule metabolic process#GO:0010604;regulation of T cell activation#GO:0050863;negative regulation of lymphocyte activation#GO:0051250;negative regulation of leukocyte activation#GO:0002695;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;negative regulation of metabolic process#GO:0009892;regulation of lymphocyte activation#GO:0051249;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000006029.3|UniProtKB=A0A5F8GPX9 A0A5F8GPX9 PTHR15431:SF21 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN CENTROSOMAL PROTEIN 20 cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 centrosome#GO:0005813;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cilium#GO:0005929;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 MONDO|Ensembl=ENSMODG00000048849.1|UniProtKB=A0A5F8GGG8 A0A5F8GGG8 LOC100617249 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000001948.4|UniProtKB=F6VJS6 F6VJS6 GNB5 PTHR19850:SF36 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-5 signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;G protein-coupled dopamine receptor signaling pathway#GO:0007212;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cytoplasmic side of membrane#GO:0098562;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165 heterotrimeric G-protein#PC00117;G-protein#PC00020;protein-binding activity modulator#PC00095 Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta5L#P00748;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;PI3 kinase pathway#P00048>Gbetagamma#P01188;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Enkephalin release#P05913>G-Protein (i)#P05974;Enkephalin release#P05913>G-Protein (s)#P05977;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085 MONDO|Ensembl=ENSMODG00000020094.3|UniProtKB=F7ESP1 F7ESP1 P2RX3 PTHR10125:SF8 P2X PURINOCEPTOR P2X PURINOCEPTOR 3 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 cellular process#GO:0009987;calcium ion transmembrane transport#GO:0070588;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;transport#GO:0006810;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000010932.3|UniProtKB=P49141 P49141 TTR PTHR10395:SF12 URICASE AND TRANSTHYRETIN-RELATED TRANSTHYRETIN nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000007832.4|UniProtKB=F7ETG7 F7ETG7 KDELR2 PTHR10585:SF37 ER LUMEN PROTEIN RETAINING RECEPTOR ER LUMEN PROTEIN-RETAINING RECEPTOR 2 signal sequence receptor activity#GO:0005048 cellular localization#GO:0051641;protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987 Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cis-Golgi network#GO:0005801;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000003884.4|UniProtKB=F7E578 F7E578 FOXP1 PTHR45796:SF3 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000011474.3|UniProtKB=F6VK05 F6VK05 LOC100023025 PTHR26450:SF63 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52Z1P olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021505.4|UniProtKB=A0A5F8G5U8 A0A5F8G5U8 PTHR10972:SF53 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 1 small molecule binding#GO:0036094;binding#GO:0005488;sterol binding#GO:0032934;alcohol binding#GO:0043178;cholesterol binding#GO:0015485;steroid binding#GO:0005496;lipid binding#GO:0008289 cytosol#GO:0005829;membrane#GO:0016020;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000045956.1|UniProtKB=A0A5F8GK64 A0A5F8GK64 PTHR10500:SF7 BETA-MICROSEMINOPROTEIN MICROSEMINOPROTEIN BETA intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000010715.4|UniProtKB=F7G7U8 F7G7U8 PEX1 PTHR23077:SF12 AAA-FAMILY ATPASE PEROXISOMAL ATPASE PEX1 ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 cellular component organization#GO:0016043;protein import into peroxisome matrix#GO:0016558;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031;peroxisomal transport#GO:0043574;protein transport#GO:0015031;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytosol#GO:0005829;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000005513.4|UniProtKB=F7G5M0 F7G5M0 ZDHHC22 PTHR22883:SF213 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC22 catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 protein targeting#GO:0006605;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;developmental maturation#GO:0021700;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188;vesicle organization#GO:0016050;protein targeting to membrane#GO:0006612;developmental process#GO:0032502 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000002122.4|UniProtKB=A0A5F8HD35 A0A5F8HD35 CELSR2 PTHR24026:SF32 FAT ATYPICAL CADHERIN-RELATED CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 2 neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;axon development#GO:0061564;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030 adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell-cell junction#GO:0005911 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000003748.4|UniProtKB=F7ECQ8 F7ECQ8 PTHR21678:SF7 GROWTH INHIBITION AND DIFFERENTIATION RELATED PROTEIN 88 COILED-COIL DOMAIN-CONTAINING PROTEIN R3HCC1L MONDO|Ensembl=ENSMODG00000008824.4|UniProtKB=F6XVM0 F6XVM0 FAR1 PTHR11011:SF119 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE 1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000017404.5|UniProtKB=F6VBB2 F6VBB2 YARS1 PTHR11586:SF43 TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER TYROSINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 translational protein#PC00263 MONDO|Ensembl=ENSMODG00000005618.4|UniProtKB=F7CZ80 F7CZ80 PTHR14002:SF1 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ENDOGLIN transmembrane signaling receptor activity#GO:0004888;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;cytokine receptor binding#GO:0005126;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;growth factor binding#GO:0019838;transforming growth factor beta receptor activity#GO:0005024;kinase activity#GO:0016301;carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102;molecular transducer activity#GO:0060089;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transforming growth factor beta binding#GO:0050431;transmembrane receptor protein kinase activity#GO:0019199;cytokine binding#GO:0019955;catalytic activity, acting on a protein#GO:0140096 cellular response to growth factor stimulus#GO:0071363;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;blood vessel morphogenesis#GO:0048514;vasculature development#GO:0001944;multicellular organism development#GO:0007275;animal organ development#GO:0048513;mesenchymal cell differentiation#GO:0048762;cell surface receptor signaling pathway#GO:0007166;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;vasculogenesis#GO:0001570;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;response to transforming growth factor beta#GO:0071559;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;tube morphogenesis#GO:0035239;cellular response to transforming growth factor beta stimulus#GO:0071560;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;mesenchyme development#GO:0060485;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;tube development#GO:0035295;tissue development#GO:0009888;multicellular organismal process#GO:0032501 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016378.3|UniProtKB=F7ER73 F7ER73 PRKAR2B PTHR11635:SF156 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE II-BETA REGULATORY SUBUNIT heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;kinase inhibitor activity#GO:0019210;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;carbohydrate derivative binding#GO:0097367;protein kinase A binding#GO:0051018;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein kinase inhibitor activity#GO:0004860;nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;GABA-B receptor II signaling#P05731>PKA#P05752;Endothelin signaling pathway#P00019>PKA#P00570;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Enkephalin release#P05913>PKA#P05972;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Hedgehog signaling pathway#P00025>PKA#P00682;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491 MONDO|Ensembl=ENSMODG00000045998.1|UniProtKB=A0A5F8GFM5 A0A5F8GFM5 XRCC2 PTHR46644:SF4 DNA REPAIR PROTEIN XRCC2 DNA REPAIR PROTEIN XRCC2 nucleic acid binding#GO:0003676;binding#GO:0005488;four-way junction DNA binding#GO:0000400;DNA binding#GO:0003677 double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;replication fork#GO:0005657;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000040601.1|UniProtKB=A0A5F8GQ76 A0A5F8GQ76 LOC130455201 PTHR26452:SF825 OLFACTORY RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000005472.4|UniProtKB=F7CG94 F7CG94 VIPR2 PTHR45620:SF22 PDF RECEPTOR-LIKE PROTEIN-RELATED VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2 G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005848.4|UniProtKB=F6TKZ3 F6TKZ3 LBR PTHR21257:SF55 DELTA(14)-STEROL REDUCTASE DELTA(14)-STEROL REDUCTASE LBR catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;primary metabolic process#GO:0044238;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;secondary alcohol biosynthetic process#GO:1902653;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;nuclear membrane#GO:0031965;nuclear inner membrane#GO:0005637;organelle membrane#GO:0031090;membrane#GO:0016020;organelle inner membrane#GO:0019866;nucleus#GO:0005634;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 reductase#PC00198;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000007131.5|UniProtKB=F6RZS2 F6RZS2 FGD5 PTHR12673:SF13 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 5 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000007222.2|UniProtKB=F6WCW3 F6WCW3 SUMO2 PTHR10562:SF74 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 3 protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 p53 pathway#P00059>Sumo-1 ligase#P04635 MONDO|Ensembl=ENSMODG00000028186.2|UniProtKB=K7E4V4 K7E4V4 PTHR47500:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 21 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000018676.4|UniProtKB=H9H8S6 H9H8S6 POU6F1 PTHR11636:SF6 POU DOMAIN POU DOMAIN, CLASS 6, TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000013390.4|UniProtKB=A0A5F8GXB2 A0A5F8GXB2 TBC1D17 PTHR22957:SF360 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 17 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000039022.1|UniProtKB=A0A5F8H9E3 A0A5F8H9E3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000001891.4|UniProtKB=A0A5F8GH75 A0A5F8GH75 NXPE3 PTHR16165:SF9 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 3 MONDO|Ensembl=ENSMODG00000000475.3|UniProtKB=F6UAQ4 F6UAQ4 DISP2 PTHR45951:SF2 PROTEIN DISPATCHED-RELATED PROTEIN DISPATCHED HOMOLOG 2 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;smoothened signaling pathway#GO:0007224;cell communication#GO:0007154 membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000001176.4|UniProtKB=F6RQG3 F6RQG3 CCDC190 PTHR36871:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 190 COILED-COIL DOMAIN-CONTAINING PROTEIN 190 MONDO|Ensembl=ENSMODG00000005559.4|UniProtKB=F7F3Y2 F7F3Y2 PTHR10625:SF43 HISTONE DEACETYLASE HDAC1-RELATED POLYAMINE DEACETYLASE HDAC10 histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;epigenetic regulation of gene expression#GO:0040029;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 cytosol#GO:0005829;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000017719.4|UniProtKB=F7FHH4 F7FHH4 FHL3 PTHR24205:SF5 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS PROTEIN 3 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000009580.4|UniProtKB=F7AX03 F7AX03 IMMP1L PTHR12383:SF16 PROTEASE FAMILY S26 MITOCHONDRIAL INNER MEMBRANE PROTEASE-RELATED MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 1 protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000014152.3|UniProtKB=F6X324 F6X324 ZBTB22 PTHR24394:SF68 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 524 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000046296.1|UniProtKB=A0A5F8H4C5 A0A5F8H4C5 PTHR24068:SF543 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 D3 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein K11-linked ubiquitination#GO:0070979;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000010800.2|UniProtKB=F7C035 F7C035 GOT1L1 PTHR11879:SF6 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE, CYTOPLASMIC 2 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;transferase#PC00220;transaminase#PC00216 Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854 MONDO|Ensembl=ENSMODG00000016961.3|UniProtKB=F6V5E1 F6V5E1 UBQLN4 PTHR10677:SF21 UBIQUILIN UBIQUILIN-4 protein binding#GO:0005515;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000021280.4|UniProtKB=F7GEB2 F7GEB2 GPR87 PTHR24233:SF8 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 87 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000040970.1|UniProtKB=A0A5F8H2C1 A0A5F8H2C1 PTHR24070:SF396 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN R-RAS2 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;establishment or maintenance of cell polarity#GO:0007163;Ras protein signal transduction#GO:0007265;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 EGF receptor signaling pathway#P00018>Ras#P00552;TGF-beta signaling pathway#P00052>Ras-GDP#P01291;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;TGF-beta signaling pathway#P00052>Ras-GTP#P01280 MONDO|Ensembl=ENSMODG00000020506.4|UniProtKB=H9H7K5 H9H7K5 PTHR10125:SF9 P2X PURINOCEPTOR P2X PURINOCEPTOR 1 monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 calcium ion transmembrane transport#GO:0070588;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000017569.4|UniProtKB=F7BSG0 F7BSG0 ENPP3 PTHR10151:SF107 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 3 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity#GO:0016787 negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;nucleoside triphosphate metabolic process#GO:0009141;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000016934.5|UniProtKB=F6VMX5 F6VMX5 VGLL3 PTHR15950:SF16 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 3 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000011301.4|UniProtKB=F6WYV7 F6WYV7 GFAP PTHR45652:SF9 GLIAL FIBRILLARY ACIDIC PROTEIN GLIAL FIBRILLARY ACIDIC PROTEIN structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;supramolecular fiber organization#GO:0097435;regulation of protein catabolic process#GO:0042176;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;cellular component organization#GO:0016043;regulation of macromolecule metabolic process#GO:0060255;intermediate filament cytoskeleton organization#GO:0045104;regulation of cellular process#GO:0050794;regulation of catabolic process#GO:0009894;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 intermediate filament#PC00129;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000037316.1|UniProtKB=K7E4K6 K7E4K6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000002991.3|UniProtKB=F6Q4E9 F6Q4E9 LOC100010526 PTHR10797:SF79 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 7 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;CCR4-NOT complex#GO:0030014;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 mRNA polyadenylation factor#PC00146;RNA processing factor#PC00147;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000021401.4|UniProtKB=K7E4F3 K7E4F3 PTHR46292:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 102A COILED-COIL DOMAIN-CONTAINING PROTEIN 102B MONDO|Ensembl=ENSMODG00000024216.2|UniProtKB=F6W000 F6W000 PTHR31463:SF5 MACROPHAGE-EXPRESSED GENE 1 PROTEIN MACPF DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000007691.3|UniProtKB=F7F9T4 F7F9T4 PTHR43986:SF1 ELONGATION FACTOR 1-GAMMA ELONGATION FACTOR 1-GAMMA cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000002672.4|UniProtKB=F7CYZ5 F7CYZ5 FAAP100 PTHR14890:SF1 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 100 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 100 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000018877.4|UniProtKB=F7DA88 F7DA88 FAT4 PTHR24026:SF140 FAT ATYPICAL CADHERIN-RELATED PROTOCADHERIN FAT 4 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell-cell junction#GO:0005911;adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000038029.1|UniProtKB=A0A5F8GQD7 A0A5F8GQD7 MRPL27 PTHR15893:SF17 RIBOSOMAL PROTEIN L27 LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000006249.4|UniProtKB=F7FEC2 F7FEC2 TSEN2 PTHR21227:SF0 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2 RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;phosphorus-oxygen lyase activity#GO:0016849;lyase activity#GO:0016829;catalytic activity, acting on a tRNA#GO:0140101;nuclease activity#GO:0004518 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 DNA metabolism protein#PC00009;endodeoxyribonuclease#PC00093 MONDO|Ensembl=ENSMODG00000006766.4|UniProtKB=F7BU61 F7BU61 GABRP PTHR18945:SF33 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT PI transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;molecular transducer activity#GO:0060089;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;neurotransmitter receptor activity#GO:0030594;chloride channel activity#GO:0005254;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888 establishment of localization#GO:0051234;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;transmembrane transport#GO:0055085;localization#GO:0051179;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;synapse#GO:0045202;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;cell junction#GO:0030054 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000019760.4|UniProtKB=F6WMQ4 F6WMQ4 SCAI PTHR21243:SF21 PROTEIN SCAI PROTEIN SCAI transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000000515.3|UniProtKB=F6Y5I6 F6Y5I6 PLEKHH2 PTHR22903:SF3 PLEKHH PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 2 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 regulation of actin filament depolymerization#GO:0030834;regulation of cellular component organization#GO:0051128;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of organelle organization#GO:0010639;cellular component organization#GO:0016043;negative regulation of cellular component organization#GO:0051129;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of actin filament length#GO:0030832;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;negative regulation of protein depolymerization#GO:1901880;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of protein-containing complex disassembly#GO:0043244;regulation of protein depolymerization#GO:1901879;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000006640.4|UniProtKB=F7G4A8 F7G4A8 PTGR2 PTHR43205:SF5 PROSTAGLANDIN REDUCTASE PROSTAGLANDIN REDUCTASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;icosanoid metabolic process#GO:0006690;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;prostaglandin metabolic process#GO:0006693;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 reductase#PC00198 MONDO|Ensembl=ENSMODG00000000490.4|UniProtKB=F6U9N1 F6U9N1 CCDC9B PTHR15635:SF10 COILED-COIL DOMAIN CONTAINING PROTEIN 9 COILED-COIL DOMAIN-CONTAINING PROTEIN 9B MONDO|Ensembl=ENSMODG00000044321.1|UniProtKB=A0A5F8H717 A0A5F8H717 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000006649.4|UniProtKB=F6ZJJ7 F6ZJJ7 TMEM87B PTHR21229:SF16 LUNG SEVEN TRANSMEMBRANE RECEPTOR TRANSMEMBRANE PROTEIN 87B establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038220.1|UniProtKB=A0A5F8GDC7 A0A5F8GDC7 PTHR13958:SF3 CENTROSOME-ASSOCIATED PROTEIN 350 CAP-GLY DOMAIN-CONTAINING PROTEIN-RELATED microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000015918.4|UniProtKB=F6ZR73 F6ZR73 PIKFYVE PTHR46715:SF1 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 leukocyte migration#GO:0050900;phagocytosis#GO:0006909;lipid metabolic process#GO:0006629;transport#GO:0006810;lytic vacuole organization#GO:0080171;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;leukocyte chemotaxis#GO:0030595;membrane fusion#GO:0061025;organophosphate metabolic process#GO:0019637;regulation of metabolic process#GO:0019222;cell migration#GO:0016477;biological regulation#GO:0065007;membrane organization#GO:0061024;organelle assembly#GO:0070925;pigmentation#GO:0043473;chemotaxis#GO:0006935;localization#GO:0051179;vacuole organization#GO:0007033;cell chemotaxis#GO:0060326;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell motility#GO:0048870;phospholipid metabolic process#GO:0006644;vesicle fusion#GO:0006906;locomotion#GO:0040011;phagolysosome assembly#GO:0001845;metabolic process#GO:0008152;neutrophil chemotaxis#GO:0030593;melanosome organization#GO:0032438;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;vesicle organization#GO:0016050;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;lysosome organization#GO:0007040;organelle fusion#GO:0048284;neutrophil migration#GO:1990266;glycerophospholipid metabolic process#GO:0006650;taxis#GO:0042330;response to chemical#GO:0042221;cellular component assembly#GO:0022607;granulocyte migration#GO:0097530;vesicle-mediated transport#GO:0016192;organelle membrane fusion#GO:0090174;cellular pigmentation#GO:0033059;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;regulation of reactive oxygen species metabolic process#GO:2000377;cellular component organization#GO:0016043;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;glycerolipid metabolic process#GO:0046486;endocytosis#GO:0006897 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;phagocytic vesicle#GO:0045335;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000006033.4|UniProtKB=F6ZUZ8 F6ZUZ8 LIN9 PTHR21689:SF2 LIN-9 PROTEIN LIN-9 HOMOLOG DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000006761.3|UniProtKB=A0A5F8GMQ0 A0A5F8GMQ0 ASB6 PTHR24132:SF24 ANKYRIN REPEAT AND SOCS BOX PROTEIN 6 ANKYRIN REPEAT AND SOCS BOX PROTEIN 6 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013910.4|UniProtKB=A0A5F8HH75 A0A5F8HH75 ILRUN PTHR20930:SF10 OVARIAN CARCINOMA ANTIGEN CA125-RELATED PROTEIN ILRUN regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;protein targeting to vacuole#GO:0006623;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;cellular process#GO:0009987;regulation of localization#GO:0032879;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;cellular localization#GO:0051641;regulation of protein localization#GO:0032880;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;intracellular protein localization#GO:0008104;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;negative regulation of multicellular organismal process#GO:0051241;localization#GO:0051179;protein localization to vacuole#GO:0072665 intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000003913.4|UniProtKB=A0A5F8GNS6 A0A5F8GNS6 ATG9B PTHR13038:SF14 APG9 AUTOPHAGY 9 AUTOPHAGY-RELATED PROTEIN 9B transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;intramembrane lipid carrier activity#GO:0140303 cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;autophagosome assembly#GO:0000045;intracellular protein localization#GO:0008104;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;reticulophagy#GO:0061709;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;phagophore assembly site#GO:0000407;autophagosome#GO:0005776;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000042104.1|UniProtKB=A0A5F8H8E6 A0A5F8H8E6 PTHR23235:SF198 KRUEPPEL-LIKE TRANSCRIPTION FACTOR ZINC FINGER PROTEIN 513 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000001584.4|UniProtKB=F7ACM1 F7ACM1 ASB3 PTHR46224:SF6 ANKYRIN REPEAT FAMILY PROTEIN IQ MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000017246.3|UniProtKB=A0A5F8GJ12 A0A5F8GJ12 LRRTM3 PTHR24373:SF296 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT TRANSMEMBRANE NEURONAL PROTEIN 3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019384.4|UniProtKB=F6WCU7 F6WCU7 ADAMTSL3 PTHR13723:SF169 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 3 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;external encapsulating structure organization#GO:0045229;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000042100.1|UniProtKB=A0A5F8GT50 A0A5F8GT50 LOC100015635 PTHR24247:SF195 5-HYDROXYTRYPTAMINE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN-RELATED molecular transducer activity#GO:0060089;acetylcholine receptor activity#GO:0015464;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;synaptic signaling#GO:0099536;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052 cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000025628.2|UniProtKB=A0A5F8H3E5 A0A5F8H3E5 TRIR PTHR34753:SF1 TELOMERASE RNA COMPONENT INTERACTING RNASE TELOMERASE RNA COMPONENT-INTERACTING RNASE 3'-5' exonuclease activity#GO:0008408;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;hydrolase activity#GO:0016787;exonuclease activity#GO:0004527 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000028292.2|UniProtKB=K7E1V1 K7E1V1 LOC103096141 PTHR33517:SF6 PROTEIN FAM170B-RELATED FAMILY WITH SEQUENCE SIMILARITY 170 MEMBER B reproductive process#GO:0022414;fertilization#GO:0009566;sexual reproduction#GO:0019953 MONDO|Ensembl=ENSMODG00000013079.4|UniProtKB=F7FB74 F7FB74 GRIK4 PTHR18966:SF171 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 4 transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;signaling receptor activity#GO:0038023;carboxylic acid transmembrane transporter activity#GO:0046943;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268 presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;plasma membrane protein complex#GO:0098797;postsynapse#GO:0098794;membrane protein complex#GO:0098796;postsynaptic density membrane#GO:0098839;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211 transmembrane signal receptor#PC00197 Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>KA4#P01001;Ionotropic glutamate receptor pathway#P00037>KA#P01026 MONDO|Ensembl=ENSMODG00000000603.4|UniProtKB=F6TBC0 F6TBC0 HNRNPA2B1 PTHR48026:SF13 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS A2_B1 sequence-specific DNA binding#GO:0043565;mRNA 3'-UTR binding#GO:0003730;telomeric repeat DNA binding#GO:0042162;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;RNA binding#GO:0003723;DNA binding#GO:0003677 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;mRNA processing#GO:0006397;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;transport#GO:0006810;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;establishment of RNA localization#GO:0051236;mRNA metabolic process#GO:0016071;mRNA transport#GO:0051028;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid transport#GO:0050657;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;localization#GO:0051179;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000010428.4|UniProtKB=F7F4X1 F7F4X1 PTHR26454:SF73 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000017093.3|UniProtKB=A0A5F8HFX1 A0A5F8HFX1 THBS3 PTHR10199:SF89 THROMBOSPONDIN THROMBOSPONDIN-3 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000004693.3|UniProtKB=F6TR95 F6TR95 PTHR15009:SF4 MUELLERIAN-INHIBITING FACTOR ANTI-MUELLERIAN HORMONE cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;reproductive system development#GO:0061458;system development#GO:0048731;developmental process involved in reproduction#GO:0003006;anatomical structure morphogenesis#GO:0009653;reproductive process#GO:0022414;reproductive structure development#GO:0048608;development of primary male sexual characteristics#GO:0046546;male sex differentiation#GO:0046661;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;sex differentiation#GO:0007548;multicellular organismal process#GO:0032501;gonad development#GO:0008406 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Gonadotropin-releasing hormone receptor pathway#P06664>MIS#P06750 MONDO|Ensembl=ENSMODG00000015540.5|UniProtKB=F6V0T8 F6V0T8 IGFBP2 PTHR11551:SF5 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 2 binding#GO:0005488;protein binding#GO:0005515;growth factor binding#GO:0019838 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000008744.2|UniProtKB=F6PTB5 F6PTB5 LOC100011541 PTHR26453:SF79 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2W5-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014227.4|UniProtKB=F6T9G5 F6T9G5 SAR1B PTHR45684:SF20 RE74312P SMALL COPII COAT GTPASE SAR1B hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;membrane organization#GO:0061024;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;COPII-coated vesicle budding#GO:0090114;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated membrane#GO:0048475;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle coat#GO:0030120;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;transport vesicle membrane#GO:0030658;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 MONDO|Ensembl=ENSMODG00000014478.3|UniProtKB=F6ZG57 F6ZG57 TRAPPC12 PTHR21581:SF34 D-ALANYL-D-ALANINE CARBOXYPEPTIDASE TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 12 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 serine protease#PC00203;protease#PC00190 MONDO|Ensembl=ENSMODG00000007869.2|UniProtKB=F7EB75 F7EB75 GANAB PTHR22762:SF162 ALPHA-GLUCOSIDASE NEUTRAL ALPHA-GLUCOSIDASE AB catalytic activity#GO:0003824;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;alpha-glucosidase activity#GO:0090599;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 glucosidase#PC00108 MONDO|Ensembl=ENSMODG00000016121.4|UniProtKB=F7DSQ0 F7DSQ0 OGDH PTHR23152:SF7 2-OXOGLUTARATE DEHYDROGENASE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX COMPONENT E1 catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;cellular process#GO:0009987 mitochondrion#GO:0005739;cytosol#GO:0005829;oxidoreductase complex#GO:1990204;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 TCA cycle#P00051>alphaketoglutarate Dehydrogenase#P01269 MONDO|Ensembl=ENSMODG00000018091.3|UniProtKB=F7FG42 F7FG42 CCNC PTHR10026:SF7 CYCLIN CYCLIN-C cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138;kinase modulator#PC00140 MONDO|Ensembl=ENSMODG00000042763.1|UniProtKB=A0A5F8HBQ4 A0A5F8HBQ4 RHOA PTHR24072:SF153 RHO FAMILY GTPASE TRANSFORMING PROTEIN RHOA nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001 signal transduction#GO:0007165;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;intracellular signaling cassette#GO:0141124;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;actin filament bundle organization#GO:0061572;cellular component organization#GO:0016043;signaling#GO:0023052;actomyosin structure organization#GO:0031032;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;stress fiber assembly#GO:0043149;Rho protein signal transduction#GO:0007266;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;contractile actin filament bundle assembly#GO:0030038;cell migration#GO:0016477;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;actin filament bundle assembly#GO:0051017;cellular response to stimulus#GO:0051716;regulation of cytoskeleton organization#GO:0051493;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 dendritic tree#GO:0097447;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622;dendritic spine#GO:0043197;postsynapse#GO:0098794;cell projection#GO:0042995;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cleavage furrow#GO:0032154;cell junction#GO:0030054;neuron projection#GO:0043005;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;plasma membrane#GO:0005886;cell division site#GO:0032153;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;plasma membrane region#GO:0098590 G-protein#PC00020;small GTPase#PC00208 Integrin signalling pathway#P00034>Rho#P00948;Ras Pathway#P04393>Rho#P04578;CCKR signaling map#P06959>RHOA-GDP#P07019;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoA#P00740;Axon guidance mediated by semaphorins#P00007>Rho#P00341;CCKR signaling map#P06959>RHOA-GTP#P07188;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rho#P00860;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>RhoA#P05938;Angiogenesis#P00005>GTPase#P00254 MONDO|Ensembl=ENSMODG00000045651.1|UniProtKB=F6SQR5 F6SQR5 LOC100013028 PTHR26453:SF729 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000039739.1|UniProtKB=A0A5F8GA77 A0A5F8GA77 LOC103104756 PTHR13999:SF4 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 3 defense response to symbiont#GO:0140546;signal transduction#GO:0007165;response to type II interferon#GO:0034341;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;cell surface receptor signaling pathway#GO:0007166;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;negative regulation of biological process#GO:0048519;defense response to virus#GO:0051607;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;response to peptide#GO:1901652;immune response#GO:0006955;biological regulation#GO:0065007;response to other organism#GO:0051707;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;cellular response to stimulus#GO:0051716;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;response to virus#GO:0009615 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000008389.4|UniProtKB=F7BVC8 F7BVC8 YME1L1 PTHR23076:SF144 METALLOPROTEASE M41 FTSH ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1 ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;mitochondrion organization#GO:0007005;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;cellular process#GO:0009987;organelle organization#GO:0006996;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000007360.4|UniProtKB=A0A5F8G2U6 A0A5F8G2U6 TUB PTHR16517:SF20 TUBBY-RELATED TUBBY PROTEIN HOMOLOG protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to cilium#GO:0061512;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007340.3|UniProtKB=F6TJX4 F6TJX4 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000041184.1|UniProtKB=A0A5F8GL82 A0A5F8GL82 PTHR11902:SF55 ENOLASE ALPHA-ENOLASE catalytic activity#GO:0003824;phosphopyruvate hydratase activity#GO:0004634;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;carbohydrate metabolic process#GO:0005975;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523;ADP catabolic process#GO:0046032;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;cytosol#GO:0005829 lyase#PC00144;metabolite interconversion enzyme#PC00262 Glycolysis#P00024>Enolase#P00678 MONDO|Ensembl=ENSMODG00000017150.4|UniProtKB=F6QE60 F6QE60 PMVK PTHR13101:SF1 PHOSPHOMEVALONATE KINASE PHOSPHOMEVALONATE KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776 sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;cholesterol biosynthetic process#GO:0006695;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;isoprenoid biosynthetic process#GO:0008299;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;organophosphate metabolic process#GO:0019637;acyl-CoA metabolic process#GO:0006637;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;secondary alcohol biosynthetic process#GO:1902653;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;nucleoside phosphate metabolic process#GO:0006753;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;isoprenoid metabolic process#GO:0006720;acetyl-CoA metabolic process#GO:0006084 metabolite interconversion enzyme#PC00262;kinase#PC00137;transferase#PC00220 Cholesterol biosynthesis#P00014>Phosphomevalonate kinase#P00500 MONDO|Ensembl=ENSMODG00000002695.4|UniProtKB=F7FWS7 F7FWS7 MELK PTHR24343:SF121 SERINE/THREONINE KINASE MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000051181.1|UniProtKB=A0A5F8GTV5 A0A5F8GTV5 PTHR22748:SF23 AP ENDONUCLEASE EXODEOXYRIBONUCLEASE III phosphoric diester hydrolase activity#GO:0008081;catalytic activity, acting on DNA#GO:0140097;phosphoric ester hydrolase activity#GO:0042578;3'-5' exonuclease activity#GO:0008408;DNA exonuclease activity#GO:0004529;DNA endonuclease activity#GO:0004520;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;exonuclease activity#GO:0004527;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;base-excision repair#GO:0006284;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000009050.4|UniProtKB=A0A5F8GKM6 A0A5F8GKM6 FAT2 PTHR24026:SF37 FAT ATYPICAL CADHERIN-RELATED PROTOCADHERIN FAT 2 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell-cell junction#GO:0005911;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912 cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 MONDO|Ensembl=ENSMODG00000019292.4|UniProtKB=A0A5F8G860 A0A5F8G860 PPIP5K2 PTHR12750:SF10 DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE 2 phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 nucleotide kinase#PC00172;kinase#PC00137 MONDO|Ensembl=ENSMODG00000019520.4|UniProtKB=F6VCL6 F6VCL6 ANKRD55 PTHR24123:SF85 ANKYRIN REPEAT-CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 55 system development#GO:0048731;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;animal organ development#GO:0048513;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;pancreas development#GO:0031016 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000002377.4|UniProtKB=F7G303 F7G303 EEIG2 PTHR21456:SF3 FAMILY WITH SEQUENCE SIMILARITY 102 EEIG FAMILY MEMBER 2 MONDO|Ensembl=ENSMODG00000014370.4|UniProtKB=A0A5F8GSY0 A0A5F8GSY0 DACH2 PTHR12577:SF7 DACHSHUND DACHSHUND HOMOLOG 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000003461.3|UniProtKB=A0A5F8GHV9 A0A5F8GHV9 LRPAP1 PTHR16560:SF2 ALPHA-2-MACROGLOBULIN RECEPTOR-ASSOCIATED PROTEIN ALPHA-2-MACROGLOBULIN RECEPTOR-ASSOCIATED PROTEIN signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function inhibitor activity#GO:0140678;signaling receptor inhibitor activity#GO:0030547;lipoprotein particle receptor binding#GO:0070325;protein binding#GO:0005515 regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of endocytosis#GO:0030100;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of cellular component organization#GO:0051128;negative regulation of transport#GO:0051051;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;rough endoplasmic reticulum#GO:0005791;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;organelle lumen#GO:0043233;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;cis-Golgi network#GO:0005801;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;endoplasmic reticulum lumen#GO:0005788 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000050651.1|UniProtKB=A0A5F8G5Q9 A0A5F8G5Q9 CCDC32 PTHR31800:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782;cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 MONDO|Ensembl=ENSMODG00000007408.3|UniProtKB=F7GKJ4 F7GKJ4 LOC100029259 PTHR24242:SF183 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11G2 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000015895.3|UniProtKB=F7AGI8 F7AGI8 PTRHD1 PTHR46194:SF1 PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED MONDO|Ensembl=ENSMODG00000014807.3|UniProtKB=F7DLT8 F7DLT8 VN2R504 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038710.1|UniProtKB=K7E2U1 K7E2U1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010803.2|UniProtKB=A0A5F8GME3 A0A5F8GME3 MED8 PTHR13074:SF9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000006821.4|UniProtKB=A0A5F8H4Z1 A0A5F8H4Z1 KCNIP1 PTHR23055:SF82 CALCIUM BINDING PROTEINS A-TYPE POTASSIUM CHANNEL MODULATORY PROTEIN KCNIP1 channel regulator activity#GO:0016247;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;potassium channel regulator activity#GO:0015459;transmembrane transporter binding#GO:0044325;transporter regulator activity#GO:0141108;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106 regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000036841.1|UniProtKB=A0A5F8G9J4 A0A5F8G9J4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000006797.4|UniProtKB=F6PGZ0 F6PGZ0 RGSL1 PTHR47079:SF1 REGULATOR OF G-PROTEIN SIGNALING PROTEIN-LIKE REGULATOR OF G PROTEIN SIGNALING PROTEIN-LIKE MONDO|Ensembl=ENSMODG00000028536.2|UniProtKB=K7DZV7 K7DZV7 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000048546.1|UniProtKB=F7FML9 F7FML9 PTHR45632:SF11 LD33804P KELCH-LIKE PROTEIN 13 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;protein metabolic process#GO:0019538 intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000051107.1|UniProtKB=A0A5F8GR87 A0A5F8GR87 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000011309.3|UniProtKB=F6WJC7 F6WJC7 HARS2 PTHR11476:SF6 HISTIDYL-TRNA SYNTHETASE HISTIDINE--TRNA LIGASE, MITOCHONDRIAL RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038 cytosol#GO:0005829;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000037957.1|UniProtKB=A0A5F8GPD0 A0A5F8GPD0 PTHR12509:SF17 SPERMATOGENESIS-ASSOCIATED 4-RELATED CH-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000004951.4|UniProtKB=A0A5F8HI14 A0A5F8HI14 CCDC142 PTHR21436:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 142 COILED-COIL DOMAIN-CONTAINING PROTEIN 142 MONDO|Ensembl=ENSMODG00000016734.4|UniProtKB=F7BYT1 F7BYT1 RHBDL1 PTHR45840:SF4 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 1 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 MONDO|Ensembl=ENSMODG00000021579.1|UniProtKB=Q65CI7 Q65CI7 MT-CO3 PTHR11403:SF7 CYTOCHROME C OXIDASE SUBUNIT III CYTOCHROME C OXIDASE SUBUNIT 3 monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324 electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;generation of precursor metabolites and energy#GO:0006091;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 oxidase#PC00175;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000018744.4|UniProtKB=F7EFJ2 F7EFJ2 PDZK1 PTHR14191:SF6 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR NHE-RF3-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495;protein binding#GO:0005515 intracellular protein localization#GO:0008104;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;cellular process#GO:0009987;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;protein localization to plasma membrane#GO:0072659 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000008639.4|UniProtKB=F6PGK8 F6PGK8 ING5 PTHR10333:SF41 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 5 chromatin binding#GO:0003682;histone reader activity#GO:0140566;binding#GO:0005488;histone H3 reader activity#GO:0140006;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of signal transduction#GO:0009967;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;regulation of apoptotic process#GO:0042981;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000044467.1|UniProtKB=A0A5F8G6E2 A0A5F8G6E2 DAPL1 PTHR13177:SF2 DEATH-ASSOCIATED PROTEIN 1 DEATH-ASSOCIATED PROTEIN-LIKE 1 binding#GO:0005488;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;apoptotic signaling pathway#GO:0097190;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;negative regulation of catabolic process#GO:0009895;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;negative regulation of gene expression#GO:0010629;negative regulation of translation#GO:0017148 MONDO|Ensembl=ENSMODG00000015948.4|UniProtKB=F7G1W5 F7G1W5 EPHX2 PTHR43329:SF165 EPOXIDE HYDROLASE BIFUNCTIONAL EPOXIDE HYDROLASE 2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;homeostatic process#GO:0042592;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;cholesterol homeostasis#GO:0042632;lipid modification#GO:0030258;dephosphorylation#GO:0016311 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;peroxisome#GO:0005777;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000015881.4|UniProtKB=A0A5F8G3R7 A0A5F8G3R7 AKR7L PTHR43625:SF4 AFLATOXIN B1 ALDEHYDE REDUCTASE ALDO-KETO REDUCTASE FAMILY 7 MEMBER A2 oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;reductase#PC00198 MONDO|Ensembl=ENSMODG00000007253.4|UniProtKB=F6VWT2 F6VWT2 SMC1B PTHR18937:SF147 STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 1B DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;chromosome organization#GO:0051276 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cohesin complex#GO:0008278;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000000380.4|UniProtKB=F6R8T5 F6R8T5 SCTR PTHR45620:SF13 PDF RECEPTOR-LIKE PROTEIN-RELATED SECRETIN RECEPTOR peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014990.4|UniProtKB=F7CG46 F7CG46 AOX2 PTHR11908:SF84 XANTHINE DEHYDROGENASE ALDEHYDE OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000013210.4|UniProtKB=F6Z3M5 F6Z3M5 IRX6 PTHR11211:SF16 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell development#GO:0048468;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;developmental process#GO:0032502;neuron differentiation#GO:0030182 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000012083.4|UniProtKB=F7G4T9 F7G4T9 HSPA9 PTHR19375:SF184 HEAT SHOCK PROTEIN 70KDA STRESS-70 PROTEIN, MITOCHONDRIAL ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111 protein refolding#GO:0042026;protein metabolic process#GO:0019538;protein folding#GO:0006457;iron-sulfur cluster assembly#GO:0016226;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Hsp70 family chaperone#PC00027;chaperone#PC00072 Parkinson disease#P00049>Hsp70#P01208 MONDO|Ensembl=ENSMODG00000018947.4|UniProtKB=F7GAS1 F7GAS1 PDE5A PTHR11347:SF20 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585 phosphodiesterase#PC00185;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000018434.3|UniProtKB=A0A5F8GSA8 A0A5F8GSA8 TM4SF19 PTHR14198:SF22 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 19 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000022788.3|UniProtKB=H9H7T5 H9H7T5 PTHR45616:SF69 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN 5-RELATED structural molecule activity#GO:0005198 supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;epidermis development#GO:0008544;skin development#GO:0043588;cytoskeleton organization#GO:0007010;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;cellular process#GO:0009987;organelle organization#GO:0006996 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080 MONDO|Ensembl=ENSMODG00000024136.3|UniProtKB=F6XGR8 F6XGR8 LOC100616760 PTHR24377:SF1029 IP01015P-RELATED ZINC FINGER PROTEIN 135 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000047567.1|UniProtKB=A0A5F8HCL0 A0A5F8HCL0 PTHR11627:SF1 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE A lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832;fructose-bisphosphate aldolase activity#GO:0004332;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 nicotinamide nucleotide metabolic process#GO:0046496;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;ADP catabolic process#GO:0046032;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide catabolic process#GO:0009166;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 aldolase#PC00044;lyase#PC00144 Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959;Glycolysis#P00024>Aldolase#P00679 MONDO|Ensembl=ENSMODG00000003637.3|UniProtKB=F7BM51 F7BM51 FMO3 PTHR23023:SF44 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE 3 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;biosynthetic process#GO:0009058 oxygenase#PC00177;oxidoreductase#PC00176 Nicotine degradation#P05914>FMO3#P05979 MONDO|Ensembl=ENSMODG00000041100.1|UniProtKB=A0A5F8GKS4 A0A5F8GKS4 ST3GAL2 PTHR46032:SF4 ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1 CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 2 sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transferase#PC00220 MONDO|Ensembl=ENSMODG00000015125.4|UniProtKB=F7F714 F7F714 RBMS3 PTHR24012:SF742 RNA BINDING PROTEIN RNA-BINDING MOTIF, SINGLE-STRANDED-INTERACTING PROTEIN 3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000017530.3|UniProtKB=F7EI66 F7EI66 TAAR2 PTHR24249:SF413 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 2 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000009475.4|UniProtKB=F7FNR6 F7FNR6 KIF18A PTHR24115:SF399 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF18A hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092 nuclear division#GO:0000280;organelle localization#GO:0051640;localization#GO:0051179;organelle fission#GO:0048285;cellular component disassembly#GO:0022411;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;cell cycle#GO:0007049;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic cell cycle#GO:0000278;microtubule-based movement#GO:0007018;protein-containing complex disassembly#GO:0032984;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular process#GO:0009987;microtubule depolymerization#GO:0007019;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;chromosome localization#GO:0050000 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;spindle#GO:0005819;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;cytoplasmic microtubule#GO:0005881 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000017104.4|UniProtKB=F6UKG0 F6UKG0 RTKN2 PTHR21538:SF21 ANILLIN/RHOTEKIN RTKN RHOTEKIN-2 actomyosin contractile ring assembly#GO:0000915;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;positive regulation of cell population proliferation#GO:0008284;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cytokinesis#GO:0000910;cytokinetic process#GO:0032506;cytoskeleton-dependent cytokinesis#GO:0061640;septin ring organization#GO:0031106;positive regulation of cellular process#GO:0048522;hemopoiesis#GO:0030097;biological regulation#GO:0065007;septin cytoskeleton organization#GO:0032185;developmental process#GO:0032502;cellular developmental process#GO:0048869;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cell division#GO:0051301;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127;cortical actin cytoskeleton organization#GO:0030866 contractile ring#GO:0070938;cytoskeleton#GO:0005856;actomyosin contractile ring#GO:0005826;membraneless organelle#GO:0043228;cell periphery#GO:0071944;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000003481.4|UniProtKB=F7DBM4 F7DBM4 TPCN1 PTHR46474:SF1 TWO PORE CALCIUM CHANNEL PROTEIN 1 TWO PORE CHANNEL PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765 ion channel#PC00133 CCKR signaling map#P06959>TPC1/2#P07209 MONDO|Gene=HBA|UniProtKB=Q8HY34 Q8HY34 HBA PTHR11442:SF48 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT ALPHA heme binding#GO:0020037;molecular carrier activity#GO:0140104;binding#GO:0005488;tetrapyrrole binding#GO:0046906 multicellular organismal-level homeostasis#GO:0048871;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;cellular process#GO:0009987;localization#GO:0051179;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;homeostasis of number of cells#GO:0048872;immune system process#GO:0002376;homeostatic process#GO:0042592;cell development#GO:0048468;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transfer/carrier protein#PC00219;globin#PC00107 MONDO|Ensembl=ENSMODG00000007230.4|UniProtKB=F6WCA6 F6WCA6 SLC35E3 PTHR11132:SF250 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E3 nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;nucleotide-sugar transmembrane transporter activity#GO:0005338;carbohydrate derivative transmembrane transporter activity#GO:1901505;antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000003033.4|UniProtKB=A0A5F8GZM8 A0A5F8GZM8 ADCY4 PTHR45627:SF10 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 4 cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829 metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;purine nucleotide biosynthetic process#GO:0006164;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;nucleoside phosphate biosynthetic process#GO:1901293;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 adenylate cyclase#PC00043 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760 MONDO|Ensembl=ENSMODG00000006741.5|UniProtKB=F7CD96 F7CD96 NUMB PTHR47368:SF5 NUMB PROTEIN NUMB HOMOLOG positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of cell development#GO:0060284;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;positive regulation of nervous system development#GO:0051962;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960 cytoplasm#GO:0005737;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;basal part of cell#GO:0045178;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 Notch signaling pathway#P00045>Numb#P01118 MONDO|Ensembl=ENSMODG00000006028.4|UniProtKB=A0A5F8HDB3 A0A5F8HDB3 LOC100027533 PTHR19370:SF108 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE 2 catalytic activity#GO:0003824;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;oxidoreductase activity, acting on NAD(P)H#GO:0016651 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 reductase#PC00198;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000028218.2|UniProtKB=A0A5F8GW60 A0A5F8GW60 LOC100023051 PTHR23232:SF117 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 90-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000007896.3|UniProtKB=F7FR66 F7FR66 PTHR48001:SF121 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1D2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006754.4|UniProtKB=A0A5F8H1N9 A0A5F8H1N9 GGA2 PTHR45905:SF2 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA2 small GTPase binding#GO:0031267;protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;post-Golgi vesicle-mediated transport#GO:0006892;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;Golgi to plasma membrane transport#GO:0006893;cellular process#GO:0009987;macromolecule localization#GO:0033036 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;Golgi apparatus subcompartment#GO:0098791;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 MONDO|Ensembl=ENSMODG00000001162.4|UniProtKB=A0A5F8G6G6 A0A5F8G6G6 ST7L PTHR12745:SF4 SUPPRESSION OF TUMORIGENICITY 7 SUPPRESSOR OF TUMORIGENICITY 7 PROTEIN-LIKE MONDO|Ensembl=ENSMODG00000006129.4|UniProtKB=F7E1R7 F7E1R7 DLST PTHR43416:SF5 DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220 MONDO|Ensembl=ENSMODG00000028657.2|UniProtKB=K7E612 K7E612 TIMM29 PTHR21435:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM29 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM29 organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;mitochondrial protein import pathway#GO:7770058;protein insertion into mitochondrial inner membrane#GO:0045039;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular component organization#GO:0016043;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular localization#GO:0051641 inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;TIM22 mitochondrial import inner membrane insertion complex#GO:0042721;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000050222.1|UniProtKB=A0A5F8G5D7 A0A5F8G5D7 PTHR23235:SF198 KRUEPPEL-LIKE TRANSCRIPTION FACTOR ZINC FINGER PROTEIN 513 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000014021.3|UniProtKB=F6V9H0 F6V9H0 PTHR12011:SF285 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010882.4|UniProtKB=A0A5K1UNA3 A0A5K1UNA3 PTHR10454:SF155 CASPASE CASPASE-15 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of neuron apoptotic process#GO:0043523;biological regulation#GO:0065007;tissue development#GO:0009888;regulation of apoptotic process#GO:0042981;developmental process#GO:0032502;epidermis development#GO:0008544;positive regulation of neuron apoptotic process#GO:0043525;positive regulation of apoptotic process#GO:0043065 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000048244.1|UniProtKB=A0A5F8GNR6 A0A5F8GNR6 LOC103103225 PTHR24271:SF64 KALLIKREIN-RELATED TRYPSIN serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000046096.1|UniProtKB=A0A5F8G747 A0A5F8G747 VN2R560 PTHR24061:SF599 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 26 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000011879.4|UniProtKB=A0A5F8GSB1 A0A5F8GSB1 CARMIL1 PTHR24112:SF39 LEUCINE-RICH REPEAT, ISOFORM F-RELATED F-ACTIN-UNCAPPING PROTEIN LRRC16A regulation of organelle organization#GO:0033043;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cell migration#GO:0016477;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125 cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;lamellipodium#GO:0030027;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000014420.3|UniProtKB=F7BH57 F7BH57 NR0B2 PTHR24081:SF0 NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B MEMBER 2 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulator activity#GO:0140110;binding#GO:0005488 negative regulation of biological process#GO:0048519;circadian regulation of gene expression#GO:0032922;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;rhythmic process#GO:0048511;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000008094.4|UniProtKB=A0A5F8GX18 A0A5F8GX18 KIF24 PTHR47971:SF8 KINESIN-RELATED PROTEIN 6 KINESIN-LIKE PROTEIN KIF24 microtubule motor activity#GO:0003777;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular component disassembly#GO:0022411;supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;microtubule depolymerization#GO:0007019;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular component organization#GO:0016043;cellular process#GO:0009987 microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000016424.4|UniProtKB=A0A5F8GEU7 A0A5F8GEU7 PTHR45616:SF33 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 1 structural molecule activity#GO:0005198 cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109;epithelium development#GO:0060429;epidermal cell differentiation#GO:0009913;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;cytoskeleton organization#GO:0007010;skin development#GO:0043588;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular developmental process#GO:0048869;epidermis development#GO:0008544;developmental process#GO:0032502 supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 MONDO|Ensembl=ENSMODG00000017288.2|UniProtKB=F6SM23 F6SM23 RPS27 PTHR11594:SF1 40S RIBOSOMAL PROTEIN S27 SMALL RIBOSOMAL SUBUNIT PROTEIN ES27 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;nucleic acid biosynthetic process#GO:0141187;translation#GO:0006412;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000024263.1|UniProtKB=F6ZTZ4 F6ZTZ4 LOC100016977 PTHR48018:SF168 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;signaling#GO:0023052;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000008642.3|UniProtKB=F6PGH0 F6PGH0 EXOSC5 PTHR11953:SF1 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT RRP46 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;snRNA 3'-end processing#GO:0034472;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nuclear mRNA surveillance#GO:0071028;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;regulation of gene expression#GO:0010468;snRNA processing#GO:0016180;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031;exoribonuclease#PC00099 MONDO|Ensembl=ENSMODG00000029593.2|UniProtKB=K7E3D3 K7E3D3 SRRM3 PTHR34755:SF2 SERINE/ARGININE REPETITIVE MATRIX PROTEIN 3-RELATED SERINE_ARGININE REPETITIVE MATRIX PROTEIN 3 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 MONDO|Ensembl=ENSMODG00000041599.1|UniProtKB=F6PZM8 F6PZM8 LOC100021749 PTHR26450:SF59 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000025528.3|UniProtKB=F6V246 F6V246 SCOC PTHR21614:SF0 SHORT COILED COIL PROTEIN SHORT COILED-COIL PROTEIN trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;Golgi apparatus subcompartment#GO:0098791;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 MONDO|Ensembl=ENSMODG00000011159.3|UniProtKB=F7AN22 F7AN22 LOC100021148 PTHR26450:SF111 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013078.2|UniProtKB=F7FBK8 F7FBK8 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000003530.5|UniProtKB=F7GBS9 F7GBS9 PTHR13723:SF26 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 10 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000024604.2|UniProtKB=F6PRC1 F6PRC1 MARS2 PTHR43326:SF8 METHIONYL-TRNA SYNTHETASE METHIONINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000021339.4|UniProtKB=H9H7Y4 H9H7Y4 CDK2AP2 PTHR22607:SF4 DELETED IN ORAL CANCER 1/CDK2-ASSOCIATED PROTEIN 1 CYCLIN-DEPENDENT KINASE 2-ASSOCIATED PROTEIN 2 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of microtubule-based process#GO:0032886;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of mitotic cell cycle#GO:0007346;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle#GO:0045786 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 kinase modulator#PC00140;kinase inhibitor#PC00139 MONDO|Ensembl=ENSMODG00000020635.4|UniProtKB=A0A5F8H6U9 A0A5F8H6U9 PPA2 PTHR10286:SF49 INORGANIC PYROPHOSPHATASE INORGANIC PYROPHOSPHATASE 2, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 metabolic process#GO:0008152;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 pyrophosphatase#PC00196 MONDO|Ensembl=ENSMODG00000049021.1|UniProtKB=A0A5F8HL18 A0A5F8HL18 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000021447.5|UniProtKB=F7BT39 F7BT39 ANKRD12 PTHR24149:SF14 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000039237.1|UniProtKB=A0A5F8GGS5 A0A5F8GGS5 MFSD9 PTHR23504:SF14 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 SOLUTE CARRIER FAMILY 67 MEMBER A2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000019968.3|UniProtKB=F6S9N7 F6S9N7 LOC100019962 PTHR48002:SF131 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4S2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010371.3|UniProtKB=F6R401 F6R401 GCM2 PTHR12414:SF7 GLIAL CELLS MISSING RELATED/GLIDE CHORION-SPECIFIC TRANSCRIPTION FACTOR GCMB sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;gliogenesis#GO:0042063;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000024979.1|UniProtKB=F6XP68 F6XP68 CHST12 PTHR12137:SF4 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 12 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 transferase#PC00220 MONDO|Ensembl=ENSMODG00000002864.4|UniProtKB=F7E2H8 F7E2H8 PXMP4 PTHR15460:SF3 PEROXISOMAL MEMBRANE PROTEIN 4 PEROXISOMAL MEMBRANE PROTEIN 4 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579 MONDO|Ensembl=ENSMODG00000014485.4|UniProtKB=F7FKV6 F7FKV6 TEKTL1 PTHR35081:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 105 TEKTIN-LIKE PROTEIN 1 MONDO|Ensembl=ENSMODG00000007463.4|UniProtKB=A0A5F8G3L9 A0A5F8G3L9 TPM2 PTHR19269:SF46 TROPOMYOSIN TROPOMYOSIN BETA CHAIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;muscle system process#GO:0003012;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;system process#GO:0003008;muscle contraction#GO:0006936;actin filament-based process#GO:0030029 organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;actin filament#GO:0005884 actin binding motor protein#PC00040 MONDO|Ensembl=ENSMODG00000019743.4|UniProtKB=A0A5F8G5V1 A0A5F8G5V1 AGGF1 PTHR23106:SF24 ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1 ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1 tube development#GO:0035295;multicellular organismal process#GO:0032501;circulatory system development#GO:0072359;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;system development#GO:0048731;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000019305.4|UniProtKB=F6RYG3 F6RYG3 ERAL1 PTHR42698:SF1 GTPASE ERA GTPASE ERA, MITOCHONDRIAL protein-RNA complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;ribosomal small subunit biogenesis#GO:0042274;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000020121.4|UniProtKB=F7DQX5 F7DQX5 MCTP1 PTHR45911:SF3 C2 DOMAIN-CONTAINING PROTEIN MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 regulation of secretion#GO:0051046;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of secretion by cell#GO:1903530;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of neurotransmitter secretion#GO:0046928;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789 presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000003010.3|UniProtKB=F6Q3F7 F6Q3F7 ACADS PTHR43884:SF42 ACYL-COA DEHYDROGENASE SHORT-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;short-chain fatty acid catabolic process#GO:0019626;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000003403.4|UniProtKB=F6YTA8 F6YTA8 PTHR45742:SF5 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C8 BETA CHAIN regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;positive regulation of immune response#GO:0050778;humoral immune response#GO:0006959;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;complement activation#GO:0006956;immune response#GO:0006955;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of immune response#GO:0050776;immune system process#GO:0002376;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of biological process#GO:0050789 extracellular region#GO:0005576;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 complement component#PC00078 MONDO|Ensembl=ENSMODG00000016066.3|UniProtKB=F7GIR6 F7GIR6 SYNGR3 PTHR10838:SF8 SYNAPTOGYRIN SYNAPTOGYRIN-3 transport#GO:0006810;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;secretion by cell#GO:0032940;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synaptic vesicle membrane organization#GO:0048499;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;export from cell#GO:0140352;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192 cell junction#GO:0030054;neuromuscular junction#GO:0031594;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;presynapse#GO:0098793;secretory vesicle#GO:0099503;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000027367.2|UniProtKB=K7E1U2 K7E1U2 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010303.4|UniProtKB=F6SSB6 F6SSB6 WDR13 PTHR22838:SF4 WD REPEAT PROTEIN 26-RELATED WD REPEAT-CONTAINING PROTEIN 13 binding#GO:0005488;chromatin binding#GO:0003682 MONDO|Ensembl=ENSMODG00000049254.1|UniProtKB=F7AI11 F7AI11 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011416.4|UniProtKB=A0A5F8HCN5 A0A5F8HCN5 STAB1 PTHR24038:SF8 STABILIN STABILIN-1 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000023421.3|UniProtKB=F6UEH5 F6UEH5 LOC100618223 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008637.3|UniProtKB=F6PGK3 F6PGK3 ELP3 PTHR11135:SF0 HISTONE ACETYLTRANSFERASE-RELATED ELONGATOR COMPLEX PROTEIN 3 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 nucleus#GO:0005634;elongator holoenzyme complex#GO:0033588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000019830.4|UniProtKB=A0A5F8GVB9 A0A5F8GVB9 ATP13A3 PTHR45630:SF12 CATION-TRANSPORTING ATPASE-RELATED POLYAMINE-TRANSPORTING ATPASE 13A3 polyamine transmembrane transporter activity#GO:0015203;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;transmembrane transport#GO:0055085;localization#GO:0051179;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic ion homeostasis#GO:0050801;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878 late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000006735.4|UniProtKB=A0A5F8G7V4 A0A5F8G7V4 KIF19 PTHR24115:SF434 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF19 isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000041916.1|UniProtKB=A0A5F8GKA5 A0A5F8GKA5 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000016190.3|UniProtKB=F7FYE5 F7FYE5 PTHR19441:SF39 WAP four-disulfide core domain protein WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 5 peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to bacterium#GO:0009617;immune system process#GO:0002376;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000043232.1|UniProtKB=A0A5F8G8Y0 A0A5F8G8Y0 ADPRH PTHR16222:SF26 ADP-RIBOSYLGLYCOHYDROLASE ADP-RIBOSYLHYDROLASE ARH1 catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000015306.3|UniProtKB=F6XZ55 F6XZ55 FKBP14 PTHR46222:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7/14 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP14 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000048722.1|UniProtKB=A0A5F8G810 A0A5F8G810 PTHR10709:SF11 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 1A Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cortical actin cytoskeleton organization#GO:0030866;cellular component organization or biogenesis#GO:0071840 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 Huntington disease#P00029>Arp2/3 complex#P00811;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 MONDO|Ensembl=ENSMODG00000021309.4|UniProtKB=F7G3H2 F7G3H2 KCNMB2 PTHR10258:SF5 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-2 ion channel regulator activity#GO:0099106;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 action potential#GO:0001508;detection of chemical stimulus#GO:0009593;metal ion transport#GO:0030001;response to stimulus#GO:0050896;nervous system process#GO:0050877;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;response to calcium ion#GO:0051592;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;cellular process#GO:0009987;detection of stimulus#GO:0051606;biological regulation#GO:0065007;response to chemical#GO:0042221;potassium ion transport#GO:0006813;multicellular organismal process#GO:0032501;response to metal ion#GO:0010038;transport#GO:0006810;transmission of nerve impulse#GO:0019226;system process#GO:0003008;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 ion channel#PC00133;voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000009937.4|UniProtKB=A0A5F8HJM6 A0A5F8HJM6 CSNK1A1 PTHR11909:SF20 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;signaling#GO:0023052 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242;Hedgehog signaling pathway#P00025>Casein kinase I#P00681 MONDO|Ensembl=ENSMODG00000023409.3|UniProtKB=F6Q1B0 F6Q1B0 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000015787.2|UniProtKB=F6Z431 F6Z431 ATP6V1G2 PTHR12713:SF13 VACUOLAR ATP SYNTHASE SUBUNIT G V-TYPE PROTON ATPASE SUBUNIT G 2 developmental process#GO:0032502;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;cellular homeostasis#GO:0019725;vesicle organization#GO:0016050;proton transmembrane transport#GO:1902600;synaptic vesicle maturation#GO:0016188;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;developmental maturation#GO:0021700;vesicle-mediated transport#GO:0016192;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;cellular component organization#GO:0016043;homeostatic process#GO:0042592 intracellular membrane-bounded organelle#GO:0043231;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;cation-transporting ATPase complex#GO:0090533;synaptic vesicle#GO:0008021;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;vesicle membrane#GO:0012506;membrane#GO:0016020;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular vesicle#GO:0097708;ATPase dependent transmembrane transport complex#GO:0098533;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;ATPase complex#GO:1904949;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;presynapse#GO:0098793;secretory vesicle#GO:0099503;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469 ATP synthase#PC00002 B cell activation#P00010>I kappa B#P00392 MONDO|Ensembl=ENSMODG00000021190.4|UniProtKB=F6XVW6 F6XVW6 PAX3 PTHR45636:SF17 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000019027.4|UniProtKB=F7BLK0 F7BLK0 MFHAS1 PTHR45752:SF48 LEUCINE-RICH REPEAT-CONTAINING MALIGNANT FIBROUS HISTIOCYTOMA-AMPLIFIED SEQUENCE 1 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;immune system process#GO:0002376;inflammatory response#GO:0006954;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological regulation#GO:0065007;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;immune response#GO:0006955;defense response to symbiont#GO:0140546;signal transduction#GO:0007165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000011024.4|UniProtKB=H9H6H1 H9H6H1 PTHR19956:SF5 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 2 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 2 structural molecule activity#GO:0005198 endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;nuclear envelope#GO:0005635;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882;cytoskeleton#GO:0005856;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000000195.4|UniProtKB=F6TFN3 F6TFN3 KIAA1755 PTHR45845:SF2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED KIAA1755 guanyl-nucleotide exchange factor#PC00113 MONDO|Ensembl=ENSMODG00000009724.4|UniProtKB=F6XSL2 F6XSL2 TIPIN PTHR13220:SF11 TIMELESS INTERACTING-RELATED TIMELESS-INTERACTING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;cellular response to stimulus#GO:0051716;regulation of DNA-templated DNA replication#GO:0090329;DNA replication#GO:0006260;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;DNA-templated DNA replication#GO:0006261;regulation of DNA replication#GO:0006275;cellular response to stress#GO:0033554;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;DNA metabolic process#GO:0006259;negative regulation of DNA-templated DNA replication#GO:2000104 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000051019.1|UniProtKB=A0A5F8HJZ2 A0A5F8HJZ2 PTHR23267:SF533 IMMUNOGLOBULIN LIGHT CHAIN IG KAPPA CHAIN V-III REGION MOPC 321-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000015693.4|UniProtKB=F7E0R2 F7E0R2 CAD PTHR11405:SF5 CARBAMOYLTRANSFERASE FAMILY MEMBER MULTIFUNCTIONAL PROTEIN CAD hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity#GO:0016874;hydrolase activity#GO:0016787;ligase activity, forming carbon-nitrogen bonds#GO:0016879;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812 pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;pyrimidine nucleobase metabolic process#GO:0006206 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ligase#PC00142;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Carbamoyl phosphate synthetase#P02925;Arginine biosynthesis#P02728>Carbamoyl phosphate synthase#P02845 MONDO|Ensembl=ENSMODG00000014657.4|UniProtKB=A0A5F8G6T3 A0A5F8G6T3 SEPTIN4 PTHR18884:SF71 SEPTIN SEPTIN-4 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cell division#GO:0051301;cell cycle process#GO:0022402;cell cycle#GO:0007049;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;regulation of secretion#GO:0051046;cytokinesis#GO:0000910;biological regulation#GO:0065007;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of transport#GO:0051049;intracellular protein localization#GO:0008104;regulation of localization#GO:0032879 exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cilium#GO:0005929;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;intracellular vesicle#GO:0097708;cell cortex#GO:0005938;cell junction#GO:0030054;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;secretory vesicle#GO:0099503;microtubule cytoskeleton#GO:0015630;presynapse#GO:0098793;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;motile cilium#GO:0031514;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;synaptic vesicle#GO:0008021;vesicle#GO:0031982;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;sperm flagellum#GO:0036126;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell periphery#GO:0071944 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 MONDO|Ensembl=ENSMODG00000007943.3|UniProtKB=F7G8Z2 F7G8Z2 RANGRF PTHR15837:SF6 RAN GUANINE NUCLEOTIDE RELEASE FACTOR RAN GUANINE NUCLEOTIDE RELEASE FACTOR molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;transmembrane transporter binding#GO:0044325;transporter regulator activity#GO:0141108;enzyme binding#GO:0019899;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488 circulatory system process#GO:0003013;regulation of membrane potential#GO:0042391;heart contraction#GO:0060047;system process#GO:0003008;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;heart process#GO:0003015;blood circulation#GO:0008015;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000049850.1|UniProtKB=A0A5F8H8X7 A0A5F8H8X7 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011804.4|UniProtKB=F7G6N4 F7G6N4 G6PC3 PTHR12591:SF2 GLUCOSE-6-PHOSPHATASE GLUCOSE-6-PHOSPHATASE 3 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;sugar-phosphatase activity#GO:0050308;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;small molecule biosynthetic process#GO:0044283;glucose metabolic process#GO:0006006;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;monosaccharide biosynthetic process#GO:0046364;carbohydrate biosynthetic process#GO:0016051 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphatase#PC00181;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000047333.1|UniProtKB=A0A5F8GK43 A0A5F8GK43 RHBDL2 PTHR45840:SF6 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 2 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 MONDO|Ensembl=ENSMODG00000019144.3|UniProtKB=F7EC94 F7EC94 GNA15 PTHR10218:SF217 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-15 molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 response to nitrogen compound#GO:1901698;regulation of biological quality#GO:0065008;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;action potential#GO:0001508;cellular response to stimulus#GO:0051716;regulation of membrane potential#GO:0042391;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;G protein-coupled dopamine receptor signaling pathway#GO:0007212 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552 heterotrimeric G-protein#PC00117;G-protein#PC00020 Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057;Wnt signaling pathway#P00057>Galpha#P01451;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826 MONDO|Ensembl=ENSMODG00000009297.4|UniProtKB=A0A5F8GK34 A0A5F8GK34 BIN3 PTHR47174:SF3 BRIDGING INTEGRATOR 3 BRIDGING INTEGRATOR 3 binding#GO:0005488;lipid binding#GO:0008289 transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;plasma membrane organization#GO:0007009;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;cellular process#GO:0009987;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;endocytosis#GO:0006897 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 MONDO|Ensembl=ENSMODG00000005627.5|UniProtKB=A0A5F8G2X0 A0A5F8G2X0 MAMLD1 PTHR15275:SF0 CG1 PROTEIN/F18 MASTERMIND-LIKE DOMAIN-CONTAINING PROTEIN 1 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 MONDO|Ensembl=ENSMODG00000025610.3|UniProtKB=F6QBE6 F6QBE6 LY96 PTHR15218:SF0 MD-1, MD-2 - RELATED LYMPHOCYTE ANTIGEN 96 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187 regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of signaling#GO:0023056;immune response-regulating signaling pathway#GO:0002764;detection of chemical stimulus#GO:0009593;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;activation of immune response#GO:0002253;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to lipopolysaccharide#GO:0071222;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;regulation of response to external stimulus#GO:0032101;response to chemical#GO:0042221;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;response to bacterium#GO:0009617;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;innate immune response-activating signaling pathway#GO:0002758;positive regulation of signal transduction#GO:0009967;regulation of response to biotic stimulus#GO:0002831;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stress#GO:0080134;pattern recognition receptor signaling pathway#GO:0002221;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;cellular response to molecule of bacterial origin#GO:0071219;regulation of innate immune response#GO:0045088;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;activation of innate immune response#GO:0002218;detection of stimulus#GO:0051606;response to other organism#GO:0051707;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;toll-like receptor 4 signaling pathway#GO:0034142;positive regulation of response to stimulus#GO:0048584 membrane protein complex#GO:0098796;membrane#GO:0016020;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>MD-2#P01347 MONDO|Ensembl=ENSMODG00000039479.1|UniProtKB=F6RL47 F6RL47 PTHR13005:SF2 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN CYSTEINE-RICH HYDROPHOBIC DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000006900.4|UniProtKB=A0A5F8GDU2 A0A5F8GDU2 CREM PTHR45879:SF4 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CAMP-RESPONSIVE ELEMENT MODULATOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;intracellular signaling cassette#GO:0141124;regulation of nucleobase-containing compound metabolic process#GO:0019219 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302;Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;CCKR signaling map#P06959>ICER#P07027;Enkephalin release#P05913>CREB#P05971;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 MONDO|Ensembl=ENSMODG00000022790.3|UniProtKB=H9H900 H9H900 PTHR45616:SF19 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN 90 structural molecule activity#GO:0005198 intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;keratinocyte differentiation#GO:0030216;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;epidermis development#GO:0008544;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular developmental process#GO:0048869;organelle organization#GO:0006996;cellular process#GO:0009987;epithelium development#GO:0060429;epidermal cell differentiation#GO:0009913;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;cytoskeleton organization#GO:0007010;skin development#GO:0043588 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000009922.3|UniProtKB=H9H6C7 H9H6C7 LOC100025232 PTHR26453:SF255 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002920.3|UniProtKB=A0A5F8GJY0 A0A5F8GJY0 PTHR45618:SF13 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL DICARBOXYLATE CARRIER succinate transmembrane transporter activity#GO:0015141;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;inorganic anion transport#GO:0015698;C4-dicarboxylate transport#GO:0015740;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;succinate transport#GO:0015744;dicarboxylic acid transport#GO:0006835;phosphate ion transport#GO:0006817;carboxylic acid transmembrane transport#GO:1905039;cellular process#GO:0009987 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000004298.4|UniProtKB=F6SX93 F6SX93 NR4A2 PTHR24085:SF0 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 2 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;nuclear receptor binding#GO:0016922 developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to nitrogen compound#GO:1901699;multicellular organismal process#GO:0032501;response to nitrogen compound#GO:1901698;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;cellular response to peptide hormone stimulus#GO:0071375;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725;nervous system development#GO:0007399;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;generation of neurons#GO:0048699;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to endogenous stimulus#GO:0071495;central nervous system development#GO:0007417;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to hormone stimulus#GO:0032870 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000024301.1|UniProtKB=F7EIA6 F7EIA6 LOC100617511 PTHR48018:SF166 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M5 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000050615.1|UniProtKB=A0A5F8GX67 A0A5F8GX67 LOC100012756 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012734.3|UniProtKB=F6THF7 F6THF7 PTHR12186:SF3 SIKE FAMILY MEMBER FGFR1 ONCOGENE PARTNER 2 response to wounding#GO:0009611;response to stress#GO:0006950;response to stimulus#GO:0050896 MONDO|Ensembl=ENSMODG00000048513.1|UniProtKB=A0A5F8GQL1 A0A5F8GQL1 PTHR26453:SF601 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021424.4|UniProtKB=K7E5R7 K7E5R7 CEP76 PTHR46436:SF1 CENTROSOMAL PROTEIN OF 76 KDA CENTROSOMAL PROTEIN OF 76 KDA regulation of organelle assembly#GO:1902115;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;regulation of microtubule-based process#GO:0032886 cellular anatomical structure#GO:0110165;organelle#GO:0043226;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000050524.1|UniProtKB=A0A5F8GKW6 A0A5F8GKW6 PIERCE2 PTHR20899:SF4 PIERCE HOMOLOG PIERCER OF MICROTUBULE WALL 2 PROTEIN MONDO|Ensembl=ENSMODG00000002938.4|UniProtKB=F6PM43 F6PM43 TJP2 PTHR13865:SF26 TIGHT JUNCTION PROTEIN TIGHT JUNCTION PROTEIN 2 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cell adhesion#GO:0007155;circulatory system process#GO:0003013;animal gross anatomical part developmental process#GO:0160108;protein localization to cell junction#GO:1902414;regulation of biological quality#GO:0065008;tissue homeostasis#GO:0001894;anatomical structure development#GO:0048856;localization#GO:0051179;cellular component organization#GO:0016043;cell development#GO:0048468;homeostatic process#GO:0042592;cell junction organization#GO:0034330;cell differentiation#GO:0030154;developmental process#GO:0032502;endothelial cell differentiation#GO:0045446;cell-cell junction organization#GO:0045216;multicellular organismal-level homeostasis#GO:0048871;intracellular protein localization#GO:0008104;system process#GO:0003008;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;macromolecule localization#GO:0033036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;blood circulation#GO:0008015;epithelium development#GO:0060429 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161 tight junction#PC00214;cell junction protein#PC00070 MONDO|Ensembl=ENSMODG00000000556.4|UniProtKB=A0A5F8HIH7 A0A5F8HIH7 ADGRB1 PTHR12011:SF39 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR B1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 apoptotic cell clearance#GO:0043277;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;membrane invagination#GO:0010324;transport#GO:0006810;phagocytosis#GO:0006909;biological regulation#GO:0065007;membrane organization#GO:0061024;signal transduction#GO:0007165;cellular process#GO:0009987;localization#GO:0051179;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043 dendritic tree#GO:0097447;postsynaptic density#GO:0014069;dendrite#GO:0030425;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;cell junction#GO:0030054;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 p53 pathway#P00059>BAI-1#G04699 MONDO|Ensembl=ENSMODG00000046072.1|UniProtKB=A0A5F8G7G1 A0A5F8G7G1 PTHR46460:SF1 METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE protein methyltransferase activity#GO:0008276;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000039721.1|UniProtKB=A0A5F8H167 A0A5F8H167 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000012237.4|UniProtKB=F6Z6F1 F6Z6F1 PTHR19282:SF159 TETRASPANIN TETRASPANIN-15 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000020672.4|UniProtKB=F7DLB9 F7DLB9 NFKB1 PTHR24169:SF9 NUCLEAR FACTOR NF-KAPPA-B PROTEIN NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;response to peptide#GO:1901652;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;non-canonical NF-kappaB signal transduction#GO:0038061;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;defense response to other organism#GO:0098542;intracellular signaling cassette#GO:0141124;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;canonical NF-kappaB signal transduction#GO:0007249;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;response to other organism#GO:0051707;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 Rel homology transcription factor#PC00252;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Apoptosis signaling pathway#P00006>NFkappaB#P00297;B cell activation#P00010>NFkappaB#P00370;Toll receptor signaling pathway#P00054>NFkappaB#P01354;T cell activation#P00053>NFkappaB#P01298 MONDO|Ensembl=ENSMODG00000018411.3|UniProtKB=F6Q9D2 F6Q9D2 PTHR24006:SF647 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 12 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000003186.4|UniProtKB=A0A5F8H1U5 A0A5F8H1U5 RPS6KC1 PTHR15508:SF2 RIBOSOMAL PROTEIN S6 KINASE INACTIVE RIBOSOMAL PROTEIN S6 KINASE DELTA-1 intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142 MONDO|Ensembl=ENSMODG00000006244.4|UniProtKB=F7FRW6 F7FRW6 LTBP2 PTHR24034:SF49 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 2 extracellular matrix binding#GO:0050840;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cellular process#GO:0009987 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000000927.4|UniProtKB=F7F831 F7F831 LOC100015157 PTHR11481:SF103 IMMUNOGLOBULIN FC RECEPTOR LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR III-A-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 immune system process#GO:0002376;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;adaptive immune response#GO:0002250;biological regulation#GO:0065007 plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000038408.1|UniProtKB=A0A5F8H2X5 A0A5F8H2X5 ZNF367 PTHR24390:SF124 ZINC FINGER PROTEIN TISSUE-RESIDENT T-CELL TRANSCRIPTION REGULATOR PROTEIN ZNF683 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006858.3|UniProtKB=F6Q7D5 F6Q7D5 NHERF1 PTHR14191:SF7 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR NHE-RF1 protein-membrane adaptor activity#GO:0043495;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to plasma membrane#GO:0072659;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019199.4|UniProtKB=F7FMN3 F7FMN3 PTHR21053:SF2 TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL transcription regulator activity#GO:0140110;transcription elongation factor activity#GO:0003711 cellular anatomical structure#GO:0110165;nucleoid#GO:0009295;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrial nucleoid#GO:0042645;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000013721.4|UniProtKB=A0A5F8G5C8 A0A5F8G5C8 PCIF1 PTHR21727:SF0 PHOSPHORYLATED CTD INTERACTING FACTOR 1 MRNA (2'-O-METHYLADENOSINE-N(6)-)-METHYLTRANSFERASE cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000049500.1|UniProtKB=A0A5F8HEV2 A0A5F8HEV2 PTHR23226:SF379 ZINC FINGER AND SCAN DOMAIN-CONTAINING TRANSCRIPTIONAL REPRESSOR RHIT DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000037172.1|UniProtKB=A0A5F8GDI1 A0A5F8GDI1 PTHR10094:SF25 STEROL CARRIER PROTEIN 2 SCP-2 FAMILY PROTEIN SCP2 STEROL-BINDING DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000008475.4|UniProtKB=F7G4E6 F7G4E6 SNRNP200 PTHR24075:SF5 SEC63 DOMAIN-CONTAINING U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000011432.5|UniProtKB=F6RJR8 F6RJR8 FYCO1 PTHR46753:SF2 FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 positive regulation of macroautophagy#GO:0016239;establishment of organelle localization#GO:0051656;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;positive regulation of metabolic process#GO:0009893;positive regulation of cellular component organization#GO:0051130;microtubule-based transport#GO:0099111;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of autophagy#GO:0010508;microtubule-based process#GO:0007017;regulation of macroautophagy#GO:0016241;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;localization#GO:0051179;organelle localization#GO:0051640;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705;positive regulation of cellular process#GO:0048522;vesicle localization#GO:0051648;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;vesicle cytoskeletal trafficking#GO:0099518;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;positive regulation of catabolic process#GO:0009896;transport#GO:0006810;regulation of autophagosome maturation#GO:1901096;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;autophagosome#GO:0005776;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;lytic vacuole#GO:0000323 MONDO|Ensembl=ENSMODG00000003432.4|UniProtKB=F7GCA8 F7GCA8 IQCD PTHR31598:SF1 IQ DOMAIN-CONTAINING PROTEIN D DYNEIN REGULATORY COMPLEX SUBUNIT 10 MONDO|Ensembl=ENSMODG00000000407.3|UniProtKB=F6QMJ3 F6QMJ3 ZFP36L2 PTHR12547:SF174 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36L2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;translation regulator activity#GO:0045182;mRNA 3'-UTR binding#GO:0003730;protein-RNA adaptor activity#GO:0140517;molecular adaptor activity#GO:0060090 macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000013303.4|UniProtKB=F6ZJB3 F6ZJB3 ITGA9 PTHR23220:SF69 INTEGRIN ALPHA INTEGRIN ALPHA-9 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 cell adhesion molecule#PC00069;integrin#PC00126 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853;Integrin signalling pathway#P00034>Integrin alpha#P00941 MONDO|Ensembl=ENSMODG00000016492.4|UniProtKB=F6YPV7 F6YPV7 MINPP1 PTHR20963:SF57 MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;extracellular region#GO:0005576;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphatase#PC00181;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000016028.3|UniProtKB=F6ZHV6 F6ZHV6 GNL3L PTHR11089:SF33 GTP-BINDING PROTEIN-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3-LIKE PROTEIN membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000021285.3|UniProtKB=F7GE29 F7GE29 RFC4 PTHR11669:SF20 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 4 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;replication fork#GO:0005657;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 MONDO|Ensembl=ENSMODG00000009168.5|UniProtKB=F7ADJ4 F7ADJ4 ZNF692 PTHR24393:SF157 ZINC FINGER PROTEIN ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000022913.2|UniProtKB=F6W332 F6W332 PTHR26450:SF84 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51Q1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004986.5|UniProtKB=F7GB33 F7GB33 ZC3H7A PTHR14928:SF13 MICRO-RNA BINDING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7A nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000018310.4|UniProtKB=F6PUN9 F6PUN9 SLC35A1 PTHR10231:SF66 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER CMP-SIALIC ACID TRANSPORTER nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nucleotide-sugar transmembrane transport#GO:0015780;nitrogen compound transport#GO:0071705;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transporter#PC00227 MONDO|Ensembl=ENSMODG00000000231.4|UniProtKB=F6SYM0 F6SYM0 MRE11 PTHR10139:SF9 DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;signaling#GO:0023052;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;regulation of mitotic cell cycle phase transition#GO:1901990;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;DNA recombination#GO:0006310;metabolic process#GO:0008152;double-strand break repair#GO:0006302;negative regulation of cell cycle#GO:0045786;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle checkpoint signaling#GO:0007093;nucleic acid metabolic process#GO:0090304;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;mitotic G2/M transition checkpoint#GO:0044818;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;telomere maintenance#GO:0000723;double-strand break repair via nonhomologous end joining#GO:0006303;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;meiotic DNA double-strand break formation#GO:0042138;negative regulation of mitotic cell cycle phase transition#GO:1901991;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;negative regulation of cell cycle G2/M phase transition#GO:1902750;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;telomere organization#GO:0032200;regulation of G2/M transition of mitotic cell cycle#GO:0010389;biological regulation#GO:0065007;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000011239.4|UniProtKB=A0A5F8GJ81 A0A5F8GJ81 TRPV2 PTHR10582:SF5 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 2 calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873 calcium ion import#GO:0070509;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;calcium ion transport#GO:0006816;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;import into cell#GO:0098657 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000044389.1|UniProtKB=A0A5F8GV77 A0A5F8GV77 LOC100030075 PTHR26451:SF146 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000014984.4|UniProtKB=A0A5F8HAL9 A0A5F8HAL9 THOC2 PTHR21597:SF0 THO2 PROTEIN THO COMPLEX SUBUNIT 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleocytoplasmic transport#GO:0006913;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;biosynthetic process#GO:0009058;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973 intracellular organelle#GO:0043229;transcription export complex#GO:0000346;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000001979.4|UniProtKB=F6RIH3 F6RIH3 LEO1 PTHR23146:SF0 LEO1 PROTEIN RNA POLYMERASE-ASSOCIATED PROTEIN LEO1 enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;binding#GO:0005488;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase binding#GO:0070063;transcription coregulator activity#GO:0003712;RNA polymerase core enzyme binding#GO:0043175 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000012580.4|UniProtKB=F6PJ02 F6PJ02 NME2 PTHR11349:SF116 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE B kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550 phosphorus metabolic process#GO:0006793;nucleoside triphosphate biosynthetic process#GO:0009142;metabolic process#GO:0008152;cellular process#GO:0009987;nucleoside triphosphate metabolic process#GO:0009141;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transferase#PC00220;kinase#PC00137 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 MONDO|Ensembl=ENSMODG00000010778.3|UniProtKB=F7CIS3 F7CIS3 ADRB3 PTHR24248:SF3 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR BETA-3 ADRENERGIC RECEPTOR molecular transducer activity#GO:0060089;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;hormone binding#GO:0042562;G protein-coupled amine receptor activity#GO:0008227 signaling#GO:0023052;vasodilation#GO:0042311;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;adrenergic receptor signaling pathway#GO:0071875;regulation of biological quality#GO:0065008;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;biological regulation#GO:0065007;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;system process#GO:0003008;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of anatomical structure size#GO:0090066;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Beta3 adrenergic receptor signaling pathway#P04379>Beta3#P04449 MONDO|Ensembl=ENSMODG00000019006.3|UniProtKB=A0A5F8G4L0 A0A5F8G4L0 RBPMS PTHR10501:SF25 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B RNA-BINDING PROTEIN WITH MULTIPLE SPLICING RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000011890.4|UniProtKB=F7EHC4 F7EHC4 DCAF1 PTHR13129:SF6 VPRBP PROTEIN-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;transcription factor binding#GO:0008134;catalytic activity#GO:0003824;histone kinase activity#GO:0035173;kinase activity#GO:0016301;nuclear estrogen receptor binding#GO:0030331;nuclear receptor binding#GO:0016922;transferase activity#GO:0016740;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000025143.3|UniProtKB=A0A5F8HLT6 A0A5F8HLT6 LOC100013718 PTHR11407:SF28 LYSOZYME C LYSOZYME C lysozyme activity#GO:0003796;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783 response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;response to other organism#GO:0051707;defense response to Gram-negative bacterium#GO:0050829;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000008341.4|UniProtKB=F7EKS5 F7EKS5 SOX30 PTHR47279:SF1 TRANSCRIPTION FACTOR SOX-30 TRANSCRIPTION FACTOR SOX-30 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000015587.3|UniProtKB=F6ZV32 F6ZV32 MRPL33 PTHR47037:SF1 39S RIBOSOMAL PROTEIN L33, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL33M membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000007486.1|UniProtKB=F7CQP4 F7CQP4 CA9 PTHR18952:SF18 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 9 catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 MONDO|Ensembl=ENSMODG00000047325.1|UniProtKB=A0A5F8GXE4 A0A5F8GXE4 PTHR33166:SF2 GAG_P30 DOMAIN-CONTAINING PROTEIN CORE SHELL PROTEIN GAG P30 DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000011201.4|UniProtKB=F6SQZ9 F6SQZ9 KIAA1143 PTHR31195:SF2 GEO02494P1 GEO02494P1 MONDO|Ensembl=ENSMODG00000014929.4|UniProtKB=F7FVF9 F7FVF9 C3H19orf44 PTHR22409:SF2 CHROMOSOME 19 OPEN READING FRAME 44 CHROMOSOME 19 OPEN READING FRAME 44 MONDO|Ensembl=ENSMODG00000006854.4|UniProtKB=A0A5F8HFK0 A0A5F8HFK0 PTHR43605:SF5 ACYL-COENZYME A SYNTHETASE ACYL-COENZYME A SYNTHETASE ACSM1, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;oxoacid metabolic process#GO:0043436;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ligase#PC00142;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000047676.1|UniProtKB=A0A5F8H4D0 A0A5F8H4D0 LOC103099455 PTHR31148:SF1 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;cellular component assembly#GO:0022607;gene expression#GO:0010467;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245 U1 snRNP#GO:0005685;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000018157.4|UniProtKB=A0A5F8GB42 A0A5F8GB42 SIDT1 PTHR12185:SF15 SID1 TRANSMEMBRANE FAMILY MEMEBER SID1 TRANSMEMBRANE FAMILY MEMBER 1 nucleobase-containing compound transmembrane transporter activity#GO:0015932;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;localization#GO:0051179;nucleic acid transport#GO:0050657;establishment of localization#GO:0051234;transport#GO:0006810 plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;lysosome#GO:0005764;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000005035.4|UniProtKB=F7E982 F7E982 ATP1A1 PTHR43294:SF9 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1 sodium ion transmembrane transporter activity#GO:0015081;primary active transmembrane transporter activity#GO:0015399;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829 intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;homeostatic process#GO:0042592;export from cell#GO:0140352;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;inorganic ion homeostasis#GO:0098771;monoatomic cation transport#GO:0006812;localization#GO:0051179;potassium ion homeostasis#GO:0055075;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;monoatomic ion homeostasis#GO:0050801;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;ATPase dependent transmembrane transport complex#GO:0098533;sarcolemma#GO:0042383;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000025619.3|UniProtKB=F6QB56 F6QB56 PTHR24247:SF199 5-HYDROXYTRYPTAMINE RECEPTOR HISTAMINE H4 RECEPTOR G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;acetylcholine receptor activity#GO:0015464;molecular transducer activity#GO:0060089 cell communication#GO:0007154;response to nitrogen compound#GO:1901698;trans-synaptic signaling#GO:0099537;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;response to chemical#GO:0042221;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701 cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 MONDO|Ensembl=ENSMODG00000038076.1|UniProtKB=A0A5F8GBI6 A0A5F8GBI6 PTHR11005:SF26 LYSOSOMAL ACID LIPASE-RELATED LYSOSOMAL ACID LIPASE_CHOLESTERYL ESTER HYDROLASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 hydrolase#PC00121;lipase#PC00143 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol esterase#P02830 MONDO|Ensembl=ENSMODG00000025428.3|UniProtKB=F6W2H5 F6W2H5 ZNF717 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011267.4|UniProtKB=F6R154 F6R154 CLEC3B PTHR22799:SF3 TETRANECTIN-RELATED TETRANECTIN developmental process#GO:0032502;biomineral tissue development#GO:0031214;animal gross anatomical part developmental process#GO:0160108;bone mineralization#GO:0030282;animal organ development#GO:0048513;anatomical structure development#GO:0048856;tissue development#GO:0009888;multicellular organismal process#GO:0032501;ossification#GO:0001503 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000015141.4|UniProtKB=F7CZP3 F7CZP3 RND2 PTHR24072:SF21 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHON hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639 actin filament-based process#GO:0030029;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;response to stimulus#GO:0050896;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein#PC00020;small GTPase#PC00208 Integrin signalling pathway#P00034>Rho#P00948 MONDO|Ensembl=ENSMODG00000004284.4|UniProtKB=F6TDU3 F6TDU3 TACC3 PTHR13924:SF4 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 3 intracellular transport#GO:0046907;developmental process#GO:0032502;transport#GO:0006810;multicellular organism development#GO:0007275;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;organelle localization#GO:0051640;localization#GO:0051179;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;system development#GO:0048731;cell cycle#GO:0007049;cellular component organization#GO:0016043;nuclear migration#GO:0007097;cell cycle process#GO:0022402;cell differentiation#GO:0030154;cytoplasmic microtubule organization#GO:0031122;establishment of organelle localization#GO:0051656 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922 MONDO|Ensembl=ENSMODG00000010984.2|UniProtKB=F7API2 F7API2 OR52E2 PTHR26450:SF392 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014946.4|UniProtKB=F7FI88 F7FI88 TMEM38A PTHR12454:SF3 TRIMERIC INTRACELLULAR CATION CHANNEL TRIMERIC INTRACELLULAR CATION CHANNEL TYPE A potassium channel activity#GO:0005267;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;release of sequestered calcium ion into cytosol by sarcoplasmic reticulum#GO:0014808;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;transport#GO:0006810;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;sarcoplasm#GO:0016528;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;sarcoplasmic reticulum membrane#GO:0033017;sarcoplasmic reticulum#GO:0016529;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000050618.1|UniProtKB=A0A5F8H867 A0A5F8H867 FGF10 PTHR11486:SF21 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 10 signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 chemotaxis#GO:0006935;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of cell motility#GO:2000145;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;locomotion#GO:0040011;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;response to external stimulus#GO:0009605;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;response to wounding#GO:0009611;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;wound healing#GO:0042060;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;positive chemotaxis#GO:0050918;response to stress#GO:0006950;nervous system development#GO:0007399;response to chemical#GO:0042221;taxis#GO:0042330 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000005978.4|UniProtKB=F6TMC7 F6TMC7 GTPBP4 PTHR45759:SF1 NUCLEOLAR GTP-BINDING PROTEIN 1 GTP-BINDING PROTEIN 4 RNA binding#GO:0003723;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;nucleic acid binding#GO:0003676;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 cellular process#GO:0009987;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000029257.1|UniProtKB=K7E119 K7E119 GIMD1 PTHR10903:SF103 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER GIMD1 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000011322.4|UniProtKB=F6WIK0 F6WIK0 MBOAT1 PTHR13906:SF6 PORCUPINE MEMBRANE-BOUND GLYCEROPHOSPHOLIPID O-ACYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid modification#GO:0030258 membrane#GO:0016020;cellular anatomical structure#GO:0110165 acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000024948.2|UniProtKB=F6UUP3 F6UUP3 PTHR23227:SF86 BUCENTAUR RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000020362.4|UniProtKB=F7FJZ5 F7FJZ5 PTHR13531:SF5 GEO07735P1-RELATED-RELATED TRANSMEMBRANE PROTEIN 216 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 ciliary transition zone#GO:0035869;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995 MONDO|Ensembl=ENSMODG00000020657.4|UniProtKB=F7E5Y6 F7E5Y6 BDH2 PTHR43477:SF4 DIHYDROANTICAPSIN 7-DEHYDROGENASE DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 6 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 secondary metabolic process#GO:0019748;peptide metabolic process#GO:0006518;metabolic process#GO:0008152;secondary metabolite biosynthetic process#GO:0044550;siderophore metabolic process#GO:0009237;biosynthetic process#GO:0009058;siderophore biosynthetic process#GO:0019290;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000013307.3|UniProtKB=F6YWF2 F6YWF2 DNAJB11 PTHR44298:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 11 DNAJ HOMOLOG SUBFAMILY B MEMBER 11 binding#GO:0005488;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000019893.5|UniProtKB=A0A5F8HBE1 A0A5F8HBE1 ATG13 PTHR13430:SF4 AUTOPHAGY-RELATED PROTEIN 13 AUTOPHAGY-RELATED PROTEIN 13 protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 autophagosome assembly#GO:0000045;intracellular protein localization#GO:0008104;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;localization#GO:0051179;organelle assembly#GO:0070925;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;cellular component organization#GO:0016043 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;autophagosome#GO:0005776;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;phagophore assembly site#GO:0000407;protein kinase complex#GO:1902911;cytosol#GO:0005829;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000046988.1|UniProtKB=F7GII8 F7GII8 LOC100024824 PTHR26452:SF85 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000038266.1|UniProtKB=A0A5F8H1P6 A0A5F8H1P6 TMEM47 PTHR14399:SF3 P53-INDUCED PROTEIN RELATED TRANSMEMBRANE PROTEIN 47 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000008926.5|UniProtKB=F7GL59 F7GL59 CCDC9 PTHR15635:SF11 COILED-COIL DOMAIN CONTAINING PROTEIN 9 COILED-COIL DOMAIN-CONTAINING PROTEIN 9 MONDO|Ensembl=ENSMODG00000020741.4|UniProtKB=F7A032 F7A032 KLHL8 PTHR24412:SF480 KELCH PROTEIN KELCH-LIKE PROTEIN 8 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000047758.1|UniProtKB=A0A5F8GRP9 A0A5F8GRP9 FPGT PTHR15045:SF1 FUCOSE-1-PHOSPHATE GUANYLYLTRANSFERASE FUCOSE-1-PHOSPHATE GUANYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-sugar metabolic process#GO:0009225 transferase#PC00220 MONDO|Ensembl=ENSMODG00000041038.1|UniProtKB=A0A5F8GVP0 A0A5F8GVP0 PTHR13968:SF3 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS C1_C2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000002686.3|UniProtKB=A0A5F8GJM7 A0A5F8GJM7 PTHR12757:SF3 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Huntington disease#P00029>FIP-2#P00772 MONDO|Ensembl=ENSMODG00000004017.4|UniProtKB=F7AES7 F7AES7 ZFYVE28 PTHR46465:SF3 LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of biological process#GO:0048519;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 MONDO|Ensembl=ENSMODG00000005789.3|UniProtKB=F6U3J2 F6U3J2 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011850.3|UniProtKB=F7GDG3 F7GDG3 RAD54L2 PTHR45797:SF1 RAD54-LIKE HELICASE ARIP4 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097;transcription regulator activity#GO:0140110;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;catalytic activity, acting on a nucleic acid#GO:0140640 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000038345.1|UniProtKB=K7E392 K7E392 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000016838.3|UniProtKB=A0A5F8GZS3 A0A5F8GZS3 SLC17A9 PTHR11662:SF279 SOLUTE CARRIER FAMILY 17 VOLTAGE-GATED PURINE NUCLEOTIDE UNIPORTER SLC17A9 establishment of localization#GO:0051234;localization#GO:0051179;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;carbohydrate derivative transport#GO:1901264;transport#GO:0006810;nitrogen compound transport#GO:0071705 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000001514.3|UniProtKB=F7F488 F7F488 USP1 PTHR24006:SF905 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 1 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 protease#PC00190;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000013854.4|UniProtKB=F6WQ48 F6WQ48 SLC12A5 PTHR11827:SF54 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 5 symporter activity#GO:0015293;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;chloride transmembrane transporter activity#GO:0015108;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873 inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;chloride transport#GO:0006821;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic anion transport#GO:0006820 apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;membrane#GO:0016020;neuron projection#GO:0043005;cell body#GO:0044297;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000017472.4|UniProtKB=F7FF53 F7FF53 IRAG2 PTHR15352:SF3 LYMPHOID-RESTRICTED MEMBRANE PROTEIN, JAW1 INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR ASSOCIATED 2 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000048231.1|UniProtKB=A0A5F8GS55 A0A5F8GS55 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000038281.1|UniProtKB=A0A5F8HJF3 A0A5F8HJF3 PTHR33166:SF1 GAG_P30 DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000018573.4|UniProtKB=F7FRD6 F7FRD6 CEP70 PTHR14594:SF1 CENTROSOMAL PROTEIN OF 70 KDA CENTROSOMAL PROTEIN OF 70 KDA plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000017006.4|UniProtKB=F6QF38 F6QF38 GON4L PTHR16088:SF3 YY1 ASSOCIATED PROTEIN-RELATED GON-4-LIKE PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000000514.4|UniProtKB=F7E764 F7E764 HABP4 PTHR12299:SF30 HYALURONIC ACID-BINDING PROTEIN 4 INTRACELLULAR HYALURONAN-BINDING PROTEIN 4 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of translational initiation#GO:0006446;positive regulation of protein metabolic process#GO:0051247;positive regulation of translation#GO:0045727;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;positive regulation of macromolecule metabolic process#GO:0010604;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000039562.1|UniProtKB=A0A5F8HFK6 A0A5F8HFK6 PTHR44427:SF13 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 4-RELATED cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000037272.1|UniProtKB=A0A5F8HHJ3 A0A5F8HHJ3 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000013060.4|UniProtKB=A0A5F8G7I5 A0A5F8G7I5 MDGA2 PTHR23282:SF137 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR PROTEIN 2 MONDO|Ensembl=ENSMODG00000015313.5|UniProtKB=F6XYD4 F6XYD4 ABCB6 PTHR24221:SF664 ATP-BINDING CASSETTE SUB-FAMILY B ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000010663.4|UniProtKB=A0A5F8HFX7 A0A5F8HFX7 PTHR10015:SF274 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000017623.4|UniProtKB=F6ZT57 F6ZT57 L3MBTL3 PTHR12247:SF72 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 3 histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;protein binding#GO:0005515 regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000045989.1|UniProtKB=A0A5F8HBX4 A0A5F8HBX4 PITX3 PTHR45882:SF2 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000003901.3|UniProtKB=F7D840 F7D840 LOC100019610 PTHR26453:SF29 OLFACTORY RECEPTOR OLFACTORY RECEPTOR MOR277-1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014473.4|UniProtKB=F7A5D2 F7A5D2 PTGER2 PTHR11866:SF8 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP2 SUBTYPE transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cell communication#GO:0007154;regulation of biological quality#GO:0065008;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to alcohol#GO:0097305;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;cellular response to alcohol#GO:0097306;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 MONDO|Ensembl=ENSMODG00000005489.3|UniProtKB=F7BXX6 F7BXX6 SNX5 PTHR45850:SF5 SORTING NEXIN FAMILY MEMBER SORTING NEXIN-5 ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;cellular localization#GO:0051641;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000011913.3|UniProtKB=F7E058 F7E058 RGS18 PTHR10845:SF155 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 18 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 MONDO|Ensembl=ENSMODG00000013605.3|UniProtKB=F6VVJ0 F6VVJ0 PTHR12297:SF5 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1A, MITOCHONDRIAL regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;mitochondrial respiratory chain complex assembly#GO:0033108;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000044812.1|UniProtKB=A0A5F8G341 A0A5F8G341 LOC100016866 PTHR48018:SF168 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019129.3|UniProtKB=F7EUL9 F7EUL9 PEX12 PTHR12888:SF0 PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12 PEROXISOME ASSEMBLY PROTEIN 12 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;peroxisome organization#GO:0007031;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000004403.3|UniProtKB=F6SVH7 F6SVH7 CRBN PTHR14255:SF4 CEREBLON PROTEIN CEREBLON ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 nucleus#GO:0005634;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000008573.3|UniProtKB=A0A5F8GF48 A0A5F8GF48 LOC100028993 PTHR24381:SF480 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 59 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005562.4|UniProtKB=A0A5F8GK77 A0A5F8GK77 PTHR46904:SF1 CENTROMERE PROTEIN T CENTROMERE PROTEIN T cell cycle process#GO:0022402;cellular process#GO:0009987;chromosome segregation#GO:0007059;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278 MONDO|Ensembl=ENSMODG00000007482.3|UniProtKB=H9H6A1 H9H6A1 PTHR10430:SF41 PEROXIREDOXIN PEROXIREDOXIN-5, MITOCHONDRIAL peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;catabolic process#GO:0009056;response to stimulus#GO:0050896;hydrogen peroxide metabolic process#GO:0042743;homeostatic process#GO:0042592;cellular response to stimulus#GO:0051716 microbody#GO:0042579;mitochondrion#GO:0005739;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000019701.3|UniProtKB=F6TC86 F6TC86 KGD4 PTHR31601:SF2 28S RIBOSOMAL PROTEIN S36, MITOCHONDRIAL ALPHA-KETOGLUTARATE DEHYDROGENASE COMPONENT 4 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;catalytic complex#GO:1902494;transferase complex#GO:1990234 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000000019.1|UniProtKB=F6S1F1 F6S1F1 PTHR24279:SF1 CYTOCHROME P450 CYTOCHROME P450 11B2, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 cellular response to chemical stimulus#GO:0070887;olefinic compound metabolic process#GO:0120254;response to oxygen-containing compound#GO:1901700;regulation of biological quality#GO:0065008;response to endogenous stimulus#GO:0009719;ketone metabolic process#GO:0042180;regulation of hormone levels#GO:0010817;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cellular response to hormone stimulus#GO:0032870;secondary alcohol metabolic process#GO:1902652;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;response to hormone#GO:0009725;alcohol biosynthetic process#GO:0046165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;aldehyde metabolic process#GO:0006081;response to chemical#GO:0042221;steroid metabolic process#GO:0008202;response to nitrogen compound#GO:1901698;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;hormone biosynthetic process#GO:0042446;cellular response to peptide hormone stimulus#GO:0071375;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;hormone metabolic process#GO:0042445;cellular response to nitrogen compound#GO:1901699;lipid biosynthetic process#GO:0008610;biological regulation#GO:0065007;biosynthetic process#GO:0009058;response to peptide hormone#GO:0043434 membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000007267.4|UniProtKB=F7FQW8 F7FQW8 NUP107 PTHR13003:SF2 NUP107-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP107 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;biosynthetic process#GO:0009058;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;chromosome organization#GO:0051276;intracellular protein localization#GO:0008104;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;protein transport#GO:0015031;protein import into nucleus#GO:0006606 nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear pore outer ring#GO:0031080 transporter#PC00227 MONDO|Ensembl=ENSMODG00000002287.4|UniProtKB=F7GHN1 F7GHN1 FILIP1L PTHR23166:SF4 FILAMIN/GPBP-INTERACTING PROTEIN FILAMIN A-INTERACTING PROTEIN 1-LIKE intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179;protein localization to cytoskeleton#GO:0044380;macromolecule localization#GO:0033036 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 MONDO|Ensembl=ENSMODG00000012177.3|UniProtKB=F7CY07 F7CY07 LSMEM2 PTHR37333:SF1 LEUCINE-RICH SINGLE-PASS MEMBRANE PROTEIN 2 LEUCINE-RICH SINGLE-PASS MEMBRANE PROTEIN 2 MONDO|Ensembl=ENSMODG00000003704.4|UniProtKB=F7FA92 F7FA92 GPM6A PTHR11683:SF4 MYELIN PROTEOLIPID NEURONAL MEMBRANE GLYCOPROTEIN M6-A animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of cell projection assembly#GO:0060491;neuron development#GO:0048666;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of plasma membrane bounded cell projection assembly#GO:0120032;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;regulation of cell projection organization#GO:0031344;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of filopodium assembly#GO:0051489;neurogenesis#GO:0022008;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;filopodium#GO:0030175;intracellular organelle#GO:0043229;axon#GO:0030424;growth cone#GO:0030426;axonal growth cone#GO:0044295;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuronal cell body#GO:0043025;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;cell body#GO:0044297;actin-based cell projection#GO:0098858 myelin protein#PC00161 MONDO|Ensembl=ENSMODG00000025585.3|UniProtKB=F6U2E9 F6U2E9 PTHR12411:SF1058 CYSTEINE PROTEASE FAMILY C1-RELATED DIPEPTIDYL PEPTIDASE 1 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;lysosome#GO:0005764 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000029269.2|UniProtKB=K7E2U3 K7E2U3 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000001394.4|UniProtKB=F7F5N1 F7F5N1 MACC1 PTHR15603:SF1 SH3 DOMAIN-CONTAINING PROTEIN METASTASIS-ASSOCIATED IN COLON CANCER PROTEIN 1 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000007934.2|UniProtKB=F7G953 F7G953 SMPX PTHR17416:SF0 SMALL MUSCULAR PROTEIN SMALL MUSCULAR PROTEIN cell junction#GO:0030054;sarcomere#GO:0030017;membraneless organelle#GO:0043228;contractile muscle fiber#GO:0043292;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;M band#GO:0031430;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;myofibril#GO:0030016;A band#GO:0031672;cell-substrate junction#GO:0030055;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000046369.1|UniProtKB=A0A5F8G2B7 A0A5F8G2B7 PTHR12119:SF2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX UBIQUINONE-BINDING PROTEIN QP-C CYTOCHROME B-C1 COMPLEX SUBUNIT 8 electron transport chain#GO:0022900;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091 catalytic complex#GO:1902494;respiratory chain complex III#GO:0045275;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000011898.4|UniProtKB=F7EH18 F7EH18 HNRNPD PTHR48033:SF3 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D0 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000023079.1|UniProtKB=F7ETJ3 F7ETJ3 LOC103094285 PTHR48001:SF186 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1G1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018634.4|UniProtKB=F7B2K7 F7B2K7 PLEKHB2 PTHR14309:SF8 EXPRESSED PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY B MEMBER 2 membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000008338.4|UniProtKB=F7F2L6 F7F2L6 TECPR1 PTHR23250:SF16 DYSFERLIN-RELATED TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN 1 phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;phosphatidylinositol-3-phosphate binding#GO:0032266;phospholipid binding#GO:0005543;binding#GO:0005488 cellular process#GO:0009987;autophagy#GO:0006914;cellular component organization#GO:0016043;macroautophagy#GO:0016236;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840 lysosomal membrane#GO:0005765;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000003673.3|UniProtKB=F7ABL9 F7ABL9 PTHR21533:SF17 LEUCINE-RICH PROTEIN SPERM ANNULUS POSITIONING COMPLEX SUBUNIT CHIBBY3 MONDO|Ensembl=ENSMODG00000038230.1|UniProtKB=A0A5F8GF31 A0A5F8GF31 CYP26C1 PTHR24286:SF100 CYTOCHROME P450 26 CYTOCHROME P450 26C1 monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;central nervous system development#GO:0007417;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;regulation of hormone levels#GO:0010817;anatomical structure development#GO:0048856;isoprenoid metabolic process#GO:0006720;system development#GO:0048731;regulation of biological quality#GO:0065008;oxoacid metabolic process#GO:0043436;animal gross anatomical part developmental process#GO:0160108;terpenoid metabolic process#GO:0006721;hormone metabolic process#GO:0042445;multicellular organismal process#GO:0032501;monocarboxylic acid catabolic process#GO:0072329;biological regulation#GO:0065007;nervous system development#GO:0007399;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;retinoid metabolic process#GO:0001523;multicellular organism development#GO:0007275;diterpenoid metabolic process#GO:0016101;metabolic process#GO:0008152;developmental process#GO:0032502;lipid metabolic process#GO:0006629 oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000001801.4|UniProtKB=F6Z5A8 F6Z5A8 ONECUT1 PTHR14057:SF9 TRANSCRIPTION FACTOR ONECUT HEPATOCYTE NUCLEAR FACTOR 6 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000008760.4|UniProtKB=F6RGY6 F6RGY6 HIF1A PTHR23043:SF7 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA HYPOXIA-INDUCIBLE FACTOR 1-ALPHA transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;homeostatic process#GO:0042592;cellular response to hypoxia#GO:0071456;response to abiotic stimulus#GO:0009628;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular homeostasis#GO:0019725;regulation of gene expression#GO:0010468;response to hypoxia#GO:0001666;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 Angiogenesis#P00005>HIF-1#P00214;Hypoxia response via HIF activation#P00030>HIF-1alpha#P00818;VEGF signaling pathway#P00056>HIF-1#P01401 MONDO|Ensembl=ENSMODG00000004453.3|UniProtKB=A0A5F8GFZ1 A0A5F8GFZ1 MVB12A PTHR31612:SF2 MULTIVESICULAR BODY SUBUNIT 12A MULTIVESICULAR BODY SUBUNIT 12A regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;cellular localization#GO:0051641;localization#GO:0051179;lysosomal transport#GO:0007041;endosome to lysosome transport#GO:0008333;regulation of signaling#GO:0023051;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;endosomal transport#GO:0016197;intracellular transport#GO:0046907;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;transport#GO:0006810;regulation of response to stimulus#GO:0048583;vacuolar transport#GO:0007034 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytosol#GO:0005829;vesicle membrane#GO:0012506;membrane#GO:0016020;ESCRT I complex#GO:0000813;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000008891.3|UniProtKB=F7BRH1 F7BRH1 C1H8orf74 PTHR28457:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 SIMILAR TO HUMAN CHROMOSOME 8 OPEN READING FRAME 74 MONDO|Ensembl=ENSMODG00000018159.4|UniProtKB=A0A5F8GAL2 A0A5F8GAL2 PHB2 PTHR23222:SF1 PROHIBITIN PROHIBITIN-2 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 MONDO|Ensembl=ENSMODG00000010793.4|UniProtKB=F7CIB2 F7CIB2 PTHR24376:SF85 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 600-RELATED regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000050558.1|UniProtKB=A0A5F8H0T1 A0A5F8H0T1 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002137.4|UniProtKB=F6U023 F6U023 CBX2 PTHR46860:SF1 CHROMOBOX PROTEIN HOMOLOG 2 CHROMOBOX PROTEIN HOMOLOG 2 chromatin-protein adaptor activity#GO:0140463;histone H3K9me2/3 reader activity#GO:0062072;histone reader activity#GO:0140566;histone H3 reader activity#GO:0140006;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;PcG protein complex#GO:0031519;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000015040.5|UniProtKB=A0A5F8GUG4 A0A5F8GUG4 DGKZ PTHR11255:SF43 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE ZETA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biological regulation#GO:0065007;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;neutral lipid metabolic process#GO:0006638;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474 cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cell junction#GO:0030054;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metabolite interconversion enzyme#PC00262;kinase#PC00137 Gonadotropin-releasing hormone receptor pathway#P06664>DGK-zeta#P06790 MONDO|Ensembl=ENSMODG00000001886.4|UniProtKB=F6WGH0 F6WGH0 MLLT1 PTHR47827:SF4 AHD DOMAIN-CONTAINING PROTEIN PROTEIN ENL chromatin binding#GO:0003682;binding#GO:0005488 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000004137.4|UniProtKB=A0A5F8H198 A0A5F8H198 TTYH1 PTHR12424:SF5 TWEETY-RELATED PROTEIN TWEETY HOMOLOG 1 ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;chloride channel activity#GO:0005254;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000021589.1|UniProtKB=Q65CI2 Q65CI2 ND6 PTHR11435:SF1 NADH UBIQUINONE OXIDOREDUCTASE SUBUNIT ND6 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 6 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000015080.4|UniProtKB=A0A5F8HD09 A0A5F8HD09 CALU PTHR10827:SF76 RETICULOCALBIN CALUMENIN metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000005670.3|UniProtKB=F6VKR0 F6VKR0 PTHR19339:SF0 T CELL RECEPTOR ALPHA VARIABLE 39 T CELL RECEPTOR ALPHA VARIABLE 41 MONDO|Ensembl=ENSMODG00000016192.4|UniProtKB=A0A5F8GVP2 A0A5F8GVP2 GNPTG PTHR12630:SF6 N-LINKED OLIGOSACCHARIDE PROCESSING N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNIT GAMMA carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000010577.3|UniProtKB=F7GI18 F7GI18 IMP4 PTHR22734:SF2 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 RNA binding#GO:0003723;rRNA binding#GO:0019843;binding#GO:0005488;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;small-subunit processome#GO:0032040;90S preribosome#GO:0030686;organelle lumen#GO:0043233 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000002898.3|UniProtKB=A0A5F8G247 A0A5F8G247 FBXO10 PTHR22990:SF33 F-BOX ONLY PROTEIN F-BOX ONLY PROTEIN 10 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of apoptotic process#GO:0042981;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of programmed cell death#GO:0043067;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000018500.4|UniProtKB=F7DXT9 F7DXT9 NET1 PTHR46006:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A NEUROEPITHELIAL CELL-TRANSFORMING GENE 1 PROTEIN positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000005972.4|UniProtKB=F7BNW3 F7BNW3 KCTD19 PTHR14499:SF20 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD19 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000436.4|UniProtKB=F6UT66 F6UT66 ELP2 PTHR44111:SF2 ELONGATOR COMPLEX PROTEIN 2 ELONGATOR COMPLEX PROTEIN 2 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;elongator holoenzyme complex#GO:0033588;intracellular protein-containing complex#GO:0140535 MONDO|Ensembl=ENSMODG00000038019.1|UniProtKB=A0A5F8GWX9 A0A5F8GWX9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016026.4|UniProtKB=A0A5F8GA72 A0A5F8GA72 CNNM4 PTHR12064:SF26 METAL TRANSPORTER CNNM METAL TRANSPORTER CNNM4 monoatomic cation transmembrane transporter activity#GO:0008324;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;magnesium ion transmembrane transporter activity#GO:0015095 transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;magnesium ion transport#GO:0015693;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion homeostasis#GO:0050801;metal ion transport#GO:0030001;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000048721.1|UniProtKB=A0A5F8GKQ6 A0A5F8GKQ6 PTHR19367:SF18 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 18 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000024077.1|UniProtKB=F7CH56 F7CH56 ZNHIT2 PTHR15555:SF0 ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 2 PROTEIN FON -RELATED ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000023026.2|UniProtKB=F6UXG9 F6UXG9 PTHR26452:SF222 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6B2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000041619.1|UniProtKB=A0A5F8H0S0 A0A5F8H0S0 RPL27 PTHR10497:SF0 60S RIBOSOMAL PROTEIN L27 LARGE RIBOSOMAL SUBUNIT PROTEIN EL27 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000020617.4|UniProtKB=F6ZB11 F6ZB11 ATP10D PTHR24092:SF84 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE VD intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATP-dependent activity#GO:0140657;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215 transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular process#GO:0009987;macromolecule localization#GO:0033036;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;lipid transport#GO:0006869;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000010106.4|UniProtKB=F6X4K4 F6X4K4 PTHR11487:SF0 THIOESTERASE S-ACYL FATTY ACID SYNTHASE THIOESTERASE, MEDIUM CHAIN biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 metabolite interconversion enzyme#PC00262;esterase#PC00097 MONDO|Ensembl=ENSMODG00000012954.4|UniProtKB=F7DCE5 F7DCE5 APEH PTHR42776:SF4 SERINE PEPTIDASE S9 FAMILY MEMBER ACYLAMINO-ACID-RELEASING ENZYME hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 protein modifying enzyme#PC00260;serine protease#PC00203 MONDO|Ensembl=ENSMODG00000043966.1|UniProtKB=A0A5F8HF97 A0A5F8HF97 TMEM121 PTHR31046:SF0 TRANSMEMBRANE PROTEIN 121 TRANSMEMBRANE PROTEIN 121 MONDO|Ensembl=ENSMODG00000024024.2|UniProtKB=F7E882 F7E882 HEXIM2 PTHR13469:SF3 HEXAMETHYLENE BISACETAMIDE INDUCIBLE 1 PROTEIN HEXIM2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme inhibitor activity#GO:0004857;kinase inhibitor activity#GO:0019210;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;protein kinase inhibitor activity#GO:0004860;nucleic acid binding#GO:0003676;binding#GO:0005488;enzyme regulator activity#GO:0030234;snRNA binding#GO:0017069;RNA binding#GO:0003723;molecular function inhibitor activity#GO:0140678 regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000016595.3|UniProtKB=A0A5F8HKY5 A0A5F8HKY5 GNAS PTHR10218:SF357 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(S) SUBUNIT ALPHA hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 system process#GO:0003008;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;sensory perception of chemical stimulus#GO:0007606;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562 heterotrimeric G-protein#PC00117;G-protein#PC00020 Enkephalin release#P05913>G-Protein (s)#P05977;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Endothelin signaling pathway#P00019>Gs#P00584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gsalpha#P00705;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443 MONDO|Ensembl=ENSMODG00000017452.4|UniProtKB=F6ZTT8 F6ZTT8 GPR143 PTHR15177:SF2 G-PROTEIN COUPLED RECEPTOR 143 G PROTEIN-COUPLED RECEPTOR 143 signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;amino acid binding#GO:0016597;cation binding#GO:0043169;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;organic acid binding#GO:0043177;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;neuropeptide receptor activity#GO:0008188 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;pigmentation#GO:0043473;biological regulation#GO:0065007;cellular pigmentation#GO:0033059;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;melanosome organization#GO:0032438 membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;melanosome#GO:0042470;plasma membrane#GO:0005886;apical part of cell#GO:0045177;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;apical plasma membrane#GO:0016324;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002644.4|UniProtKB=A0A5F8GZU6 A0A5F8GZU6 ERI3 PTHR23044:SF85 3'-5' EXONUCLEASE ERI1-RELATED ERI1 EXORIBONUCLEASE 3 3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;negative regulation of cellular component organization#GO:0051129;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;regulation of chromatin organization#GO:1902275;positive regulation of biosynthetic process#GO:0009891;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;negative regulation of biological process#GO:0048519;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;regulation of biological process#GO:0050789;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of cellular component organization#GO:0051128;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 exoribonuclease#PC00099 MONDO|Ensembl=ENSMODG00000044197.1|UniProtKB=A0A5F8H5N0 A0A5F8H5N0 RPRM PTHR28649:SF2 PROTEIN REPRIMO-RELATED REPRIMO, TP53 DEPENDENT G2 ARREST MEDIATOR HOMOLOG MONDO|Ensembl=ENSMODG00000012786.4|UniProtKB=F6Q9V0 F6Q9V0 PRUNE2 PTHR12112:SF11 BNIP - RELATED PROTEIN PRUNE HOMOLOG 2 programmed cell death#GO:0012501;apoptotic process#GO:0006915;cellular process#GO:0009987;cell death#GO:0008219 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 MONDO|Ensembl=ENSMODG00000000387.4|UniProtKB=A0A5F8GKW1 A0A5F8GKW1 MOCOS PTHR14237:SF96 MOLYBDOPTERIN COFACTOR SULFURASE MOSC MOLYBDENUM COFACTOR SULFURASE transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637 MONDO|Ensembl=ENSMODG00000018367.4|UniProtKB=F6RFV0 F6RFV0 PTHR24037:SF10 HEART DEVELOPMENT PROTEIN WITH EGF-LIKE DOMAINS 1 MUCIN-13 MONDO|Ensembl=ENSMODG00000049539.1|UniProtKB=A0A5F8HDH8 A0A5F8HDH8 PRRT1B PTHR14948:SF18 NG5 PROLINE RICH TRANSMEMBRANE PROTEIN 1B membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000022741.3|UniProtKB=H9H757 H9H757 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000023889.3|UniProtKB=A0A5F8GWG0 A0A5F8GWG0 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 immune effector process#GO:0002252;immune system process#GO:0002376;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000005232.4|UniProtKB=F6ZC02 F6ZC02 EIF3E PTHR10317:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224;translation factor#PC00223 MONDO|Ensembl=ENSMODG00000003869.3|UniProtKB=F7DTN1 F7DTN1 CBFA2T3 PTHR10379:SF6 MTG8 ETO EIGHT TWENTY ONE PROTEIN TRANSCRIPTIONAL COREPRESSOR CBFA2T3 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000006474.4|UniProtKB=A0A5F8G3D8 A0A5F8G3D8 STK3 PTHR48015:SF23 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE 3 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 positive regulation of apoptotic process#GO:0043065;regulation of MAPK cascade#GO:0043408;regulation of apoptotic process#GO:0042981;hippo signaling#GO:0035329;negative regulation of signal transduction#GO:0009968;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;positive regulation of cellular process#GO:0048522;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000010676.4|UniProtKB=F7C1J9 F7C1J9 XPNPEP1 PTHR43763:SF6 XAA-PRO AMINOPEPTIDASE 1 XAA-PRO AMINOPEPTIDASE 1 protease#PC00190 MONDO|Ensembl=ENSMODG00000050219.1|UniProtKB=A0A5F8GMJ6 A0A5F8GMJ6 LOC100027842 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016544.2|UniProtKB=F7E7Q3 F7E7Q3 RAB22A PTHR24073:SF910 DRAB5-RELATED RAS-RELATED PROTEIN RAB-22A hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein transport#GO:0015031;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;late endosome#GO:0005770;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 small GTPase#PC00208;G-protein#PC00020 MONDO|Ensembl=ENSMODG00000029544.2|UniProtKB=K7E3A8 K7E3A8 LOC100026891 PTHR19944:SF50 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DM ALPHA CHAIN protein-containing complex binding#GO:0044877;peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488 regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;regulation of immune response#GO:0050776;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;positive regulation of cell adhesion#GO:0045785;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;positive regulation of leukocyte activation#GO:0002696;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;positive regulation of cell-cell adhesion#GO:0022409;cellular component biogenesis#GO:0044085;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of T cell activation#GO:0050863;regulation of multicellular organismal process#GO:0051239;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of lymphocyte activation#GO:0051249 late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;late endosome#GO:0005770;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 MONDO|Ensembl=ENSMODG00000000395.3|UniProtKB=F6QNB4 F6QNB4 TNNI1 PTHR13738:SF9 TROPONIN I TROPONIN I, SLOW SKELETAL MUSCLE binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 system process#GO:0003008;heart contraction#GO:0060047;muscle contraction#GO:0006936;cardiac muscle contraction#GO:0060048;neuromuscular process#GO:0050905;nervous system process#GO:0050877;circulatory system process#GO:0003013;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;muscle system process#GO:0003012;heart process#GO:0003015 cytoskeleton#GO:0005856;sarcomere#GO:0030017;membraneless organelle#GO:0043228;contractile muscle fiber#GO:0043292;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000015261.4|UniProtKB=A0A5F8G491 A0A5F8G491 C1H16orf46 PTHR36869:SF1 CHROMOSOME 16 OPEN READING FRAME 46 CHROMOSOME 16 OPEN READING FRAME 46 MONDO|Ensembl=ENSMODG00000023776.3|UniProtKB=F6RVZ5 F6RVZ5 PTHR32178:SF8 FAM187 PROTEIN FAM187B immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000014397.4|UniProtKB=A0A5F8G2Y5 A0A5F8G2Y5 MACROH2A1 PTHR23430:SF20 HISTONE H2A CORE HISTONE MACRO-H2A.1 structural molecule activity#GO:0005198 heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase I#GO:0006356 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000014219.3|UniProtKB=F6T9V1 F6T9V1 ARL4A PTHR11711:SF139 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4A ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 MONDO|Ensembl=ENSMODG00000003130.3|UniProtKB=F7C323 F7C323 MYADML2 PTHR17068:SF5 MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER MYELOID-ASSOCIATED DIFFERENTIATION MARKER-LIKE PROTEIN 2 MONDO|Ensembl=ENSMODG00000020345.4|UniProtKB=F7FWK2 F7FWK2 CPLANE1 PTHR14492:SF4 JBTS17 CILIOGENESIS AND PLANAR POLARITY EFFECTOR 1 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929 MONDO|Ensembl=ENSMODG00000000706.4|UniProtKB=F6WLG1 F6WLG1 BCL2L15 PTHR36466:SF1 BCL-2-LIKE PROTEIN 15 BCL-2-LIKE PROTEIN 15 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000048440.1|UniProtKB=A0A5F8HFI4 A0A5F8HFI4 PTHR31253:SF0 BRI3-BINDING PROTEIN BRI3-BINDING PROTEIN cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000013862.3|UniProtKB=F6WPC8 F6WPC8 NT5DC4 PTHR12103:SF18 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 4 hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;purine nucleotide catabolic process#GO:0006195;ribonucleotide metabolic process#GO:0009259 phosphatase#PC00181;hydrolase#PC00121;nucleotide phosphatase#PC00173 MONDO|Ensembl=ENSMODG00000015637.2|UniProtKB=F7F199 F7F199 NRBP1 PTHR13902:SF48 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED NUCLEAR RECEPTOR-BINDING PROTEIN phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000013215.3|UniProtKB=F7EVX4 F7EVX4 C1QTNF5 PTHR15427:SF27 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 5 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 export from cell#GO:0140352;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein localization to extracellular region#GO:0071692;localization#GO:0051179;protein secretion#GO:0009306;establishment of localization#GO:0051234;secretion#GO:0046903;intracellular protein localization#GO:0008104;secretion by cell#GO:0032940;establishment of protein localization to extracellular region#GO:0035592;protein transport#GO:0015031;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000038806.1|UniProtKB=A0A5F8GF08 A0A5F8GF08 PTHR22779:SF2 SD17342P TRANSMEMBRANE PROTEIN 170A endoplasmic reticulum tubular network organization#GO:0071786;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 MONDO|Ensembl=ENSMODG00000016907.4|UniProtKB=F6X1B9 F6X1B9 C1QTNF8 PTHR22923:SF61 CEREBELLIN-RELATED C1Q AND TNF RELATED 8 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000016310.4|UniProtKB=F7A659 F7A659 FZD7 PTHR11309:SF31 FRIZZLED FRIZZLED-7 protein binding#GO:0005515;molecular transducer activity#GO:0060089;Wnt-protein binding#GO:0017147;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;non-canonical Wnt signaling pathway#GO:0035567;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428 MONDO|Ensembl=ENSMODG00000008273.4|UniProtKB=F6Z7R6 F6Z7R6 MRPL11 PTHR11661:SF48 60S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN UL11M nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843;structural molecule activity#GO:0005198;RNA binding#GO:0003723 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000008832.4|UniProtKB=A0A5F8GBH8 A0A5F8GBH8 WNK2 PTHR13902:SF10 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK2 protein serine/threonine kinase activity#GO:0004674;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247;protein kinase activity#GO:0004672;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of metal ion transport#GO:0010959;response to stimulus#GO:0050896;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;chemical homeostasis#GO:0048878;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of transport#GO:0051050;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000015438.4|UniProtKB=F6S4J9 F6S4J9 CADPS2 PTHR12166:SF7 CALCIUM-DEPENDENT SECRETION ACTIVATOR CALCIUM-DEPENDENT SECRETION ACTIVATOR 2 vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of transport#GO:0051049;regulation of localization#GO:0032879;exocytosis#GO:0006887;transport#GO:0006810;regulation of cellular process#GO:0050794;export from cell#GO:0140352;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of secretion#GO:0051046;localization#GO:0051179;secretion#GO:0046903;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;positive regulation of secretion#GO:0051047 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000000412.4|UniProtKB=A0A5F8HKV1 A0A5F8HKV1 PTHR13204:SF1 PTD012 PROTEIN BETA-KETO L-GULONATE DECARBOXYLASE ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;cation binding#GO:0043169;zinc ion binding#GO:0008270;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000019265.3|UniProtKB=A0A5F8GH87 A0A5F8GH87 HPGDS PTHR11571:SF224 GLUTATHIONE S-TRANSFERASE HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 transferase#PC00220 MONDO|Ensembl=ENSMODG00000000200.4|UniProtKB=F6TFE4 F6TFE4 VPS18 PTHR23323:SF29 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vacuolar transport#GO:0007034;lytic vacuole organization#GO:0080171;transport#GO:0006810;intracellular transport#GO:0046907;vesicle organization#GO:0016050;endosome organization#GO:0007032;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;lysosome organization#GO:0007040;cellular process#GO:0009987;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;vacuole organization#GO:0007033;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle tethering complex#GO:0099023;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000012850.4|UniProtKB=F7C9P7 F7C9P7 CNTN1 PTHR10075:SF148 BASIGIN RELATED CONTACTIN-1 cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000015414.4|UniProtKB=F6T3G2 F6T3G2 CNOT9 PTHR12262:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;RNA catabolic process#GO:0006401;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;regulation of mRNA metabolic process#GO:1903311;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604 ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;CCR4-NOT complex#GO:0030014;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000047553.1|UniProtKB=A0A5F8GX92 A0A5F8GX92 C11orf52 PTHR37342:SF1 HYPOTHETICAL PROTEIN LOC689959 CHROMOSOME 11 OPEN READING FRAME 52 MONDO|Ensembl=ENSMODG00000015469.4|UniProtKB=F6WWU1 F6WWU1 PTHR23037:SF7 CYTOKINE RECEPTOR INTERLEUKIN-21 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of cellular process#GO:0050794 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000015093.4|UniProtKB=F7F3D5 F7F3D5 C2 PTHR46393:SF1 SUSHI DOMAIN-CONTAINING PROTEIN COMPLEMENT FACTOR B response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to bacterium#GO:0009617;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;defense response to other organism#GO:0098542;biological regulation#GO:0065007;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;activation of immune response#GO:0002253;immune response#GO:0006955;complement activation#GO:0006956;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;humoral immune response#GO:0006959;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252 MONDO|Ensembl=ENSMODG00000016640.3|UniProtKB=F7GGZ8 F7GGZ8 MIS12 PTHR14527:SF2 PROTEIN MIS12 HOMOLOG PROTEIN MIS12 HOMOLOG cellular component assembly#GO:0022607;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;organelle fission#GO:0048285;kinetochore organization#GO:0051383;kinetochore assembly#GO:0051382;nuclear division#GO:0000280;organelle assembly#GO:0070925 condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;outer kinetochore#GO:0000940;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;kinetochore#GO:0000776;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000043385.1|UniProtKB=A0A5F8GZI8 A0A5F8GZI8 LOC100021236 PTHR45986:SF1 ZINC FINGER MATRIN-TYPE PROTEIN 2 ZINC FINGER MATRIN-TYPE PROTEIN 2 RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;U4/U6 x U5 tri-snRNP complex#GO:0046540;organelle#GO:0043226;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000000082.4|UniProtKB=A0A5F8GEL8 A0A5F8GEL8 AKAP17A PTHR12484:SF2 B-LYMPHOCYTE ANTIGEN-RELATED A-KINASE ANCHOR PROTEIN 17A protein binding#GO:0005515;protein kinase A binding#GO:0051018;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear speck#GO:0016607;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 MONDO|Ensembl=ENSMODG00000005933.3|UniProtKB=F6WWM9 F6WWM9 MSX2 PTHR24338:SF10 HOMEOBOX PROTEIN MSX HOMEOBOX PROTEIN MSX-2 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000010802.5|UniProtKB=A0A5F8HH72 A0A5F8HH72 CSNK1G1 PTHR11909:SF156 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM GAMMA-1 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 MONDO|Ensembl=ENSMODG00000005212.4|UniProtKB=F7A1Z3 F7A1Z3 REM2 PTHR45775:SF5 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C GTP-BINDING PROTEIN REM 2 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;calcium channel regulator activity#GO:0005246;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;molecular function regulator activity#GO:0098772;nucleotide binding#GO:0000166;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;transporter regulator activity#GO:0141108 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000004590.2|UniProtKB=Q95ME4 Q95ME4 NRAS PTHR24070:SF189 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE NRAS hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;Ras protein signal transduction#GO:0007265;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;PDGF signaling pathway#P00047>Ras#P01154;EGF receptor signaling pathway#P00018>Ras#P00552;Ras Pathway#P04393>Ras#P04547;Integrin signalling pathway#P00034>Ras#P00916;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;VEGF signaling pathway#P00056>Ras#P01411;PI3 kinase pathway#P00048>Ras#P01182;B cell activation#P00010>Ras#P00376;Angiogenesis#P00005>Ras#P00238;p53 pathway feedback loops 2#P04398>Ras#P04651;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;FGF signaling pathway#P00021>Ras#P00633;Interleukin signaling pathway#P00036>Ras#P00977;T cell activation#P00053>Ras#P01306 MONDO|Ensembl=ENSMODG00000017298.3|UniProtKB=F6S4Q6 F6S4Q6 CLIC3 PTHR43920:SF3 CHLORIDE INTRACELLULAR CHANNEL, ISOFORM A CHLORIDE INTRACELLULAR CHANNEL PROTEIN 3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253 monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000018462.4|UniProtKB=F7CU30 F7CU30 LOC100022496 PTHR14647:SF62 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSE-3-O-SULFOTRANSFERASE 4 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220 MONDO|Ensembl=ENSMODG00000049672.1|UniProtKB=F7B4E0 F7B4E0 LOC100030425 PTHR26452:SF310 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P3 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018514.4|UniProtKB=F7AGU7 F7AGU7 KY PTHR46333:SF3 CYTOKINESIS PROTEIN 3 KYPHOSCOLIOSIS PEPTIDASE muscle structure development#GO:0061061;cell junction organization#GO:0034330;cellular process#GO:0009987;cellular component organization#GO:0016043;neuromuscular junction development#GO:0007528;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502;synapse organization#GO:0050808;muscle organ development#GO:0007517;animal gross anatomical part developmental process#GO:0160108 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000038877.1|UniProtKB=A0A5F8GXV7 A0A5F8GXV7 PTHR19433:SF136 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 27 response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to external stimulus#GO:0009605;response to stimulus#GO:0050896 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000008100.4|UniProtKB=F7G5V9 F7G5V9 RMDN1 PTHR16056:SF16 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;mitotic spindle pole#GO:0097431;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;spindle#GO:0005819;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;spindle pole#GO:0000922;mitochondrion#GO:0005739;microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000012128.4|UniProtKB=F7FU45 F7FU45 SLC25A31 PTHR45635:SF40 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE 4 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;purine nucleotide transmembrane transporter activity#GO:0015216 regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;biological regulation#GO:0065007;regulation of mitochondrial membrane permeability#GO:0046902;regulation of membrane permeability#GO:0090559;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nitrogen compound transport#GO:0071705 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000049139.1|UniProtKB=A0A5F8HCD7 A0A5F8HCD7 PTHR33166:SF1 GAG_P30 DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000010929.4|UniProtKB=F7F4Z3 F7F4Z3 SETDB2 PTHR46024:SF3 HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS HISTONE-LYSINE N-METHYLTRANSFERASE SETDB2 protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000017741.4|UniProtKB=F6UMK8 F6UMK8 PTHR15327:SF0 MICROFIBRIL-ASSOCIATED PROTEIN MICROFIBRILLAR-ASSOCIATED PROTEIN 1 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000009596.4|UniProtKB=A0A5F8HLU2 A0A5F8HLU2 ELP4 PTHR12896:SF1 PAX6 NEIGHBOR PROTEIN PAXNEB ELONGATOR COMPLEX PROTEIN 4 RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;elongator holoenzyme complex#GO:0033588;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000000612.4|UniProtKB=F6TB04 F6TB04 ACTR3 PTHR11937:SF175 ACTIN ACTIN-RELATED PROTEIN 3 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;structural molecule activity#GO:0005198;cytoskeletal protein binding#GO:0008092 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cytoskeleton organization#GO:0007010;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;cortical actin cytoskeleton organization#GO:0030866;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 actin and actin related protein#PC00039 MONDO|Ensembl=ENSMODG00000016921.2|UniProtKB=F6VN60 F6VN60 SLC25A44 PTHR46314:SF2 SOLUTE CARRIER FAMILY 25 MEMBER 44 SOLUTE CARRIER FAMILY 25 MEMBER 44 branched-chain amino acid transmembrane transporter activity#GO:0015658;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215 branched-chain amino acid transport#GO:0015803;localization#GO:0051179;establishment of localization#GO:0051234;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 transporter#PC00227;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000036530.1|UniProtKB=A0A5F8HHE5 A0A5F8HHE5 ATRAID PTHR15926:SF1 ALL-TRANS RETINOIC ACID-INDUCED DIFFERENTIATION FACTOR ALL-TRANS RETINOIC ACID-INDUCED DIFFERENTIATION FACTOR MONDO|Ensembl=ENSMODG00000029073.2|UniProtKB=K7E5F1 K7E5F1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000016364.5|UniProtKB=A0A5F8G645 A0A5F8G645 CORO7 PTHR10856:SF20 CORONIN CORONIN-7 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;cellular component organization#GO:0016043;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;cell motility#GO:0048870;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;supramolecular fiber organization#GO:0097435;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cell periphery#GO:0071944;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 MONDO|Ensembl=ENSMODG00000018305.2|UniProtKB=A0A5F8GG94 A0A5F8GG94 PTHR10454:SF206 CASPASE CASPASE-6 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 regulation of apoptotic process#GO:0042981;positive regulation of neuron apoptotic process#GO:0043525;positive regulation of apoptotic process#GO:0043065;cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;regulation of neuron apoptotic process#GO:0043523;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190 FAS signaling pathway#P00020>Caspase6#P00596;Huntington disease#P00029>Caspase 6#P00809;FAS signaling pathway#P00020>Pro-Caspase6#P00607 MONDO|Ensembl=ENSMODG00000001270.4|UniProtKB=F7CIX3 F7CIX3 LMX1A PTHR24208:SF88 LIM/HOMEOBOX PROTEIN LHX LIM HOMEOBOX TRANSCRIPTION FACTOR 1-ALPHA double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000050657.1|UniProtKB=A0A5F8GSB5 A0A5F8GSB5 LOC103095599 PTHR24399:SF80 ZINC FINGER AND BTB DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cytokine production#GO:0001817;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000005131.4|UniProtKB=F7EQK8 F7EQK8 SLC11A2 PTHR11706:SF40 SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 2 monoatomic cation transmembrane transporter activity#GO:0008324;cation binding#GO:0043169;metal ion binding#GO:0046872;iron ion transmembrane transporter activity#GO:0005381;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion transmembrane transporter activity#GO:0046915;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;iron ion transmembrane transport#GO:0034755;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000045238.1|UniProtKB=A0A5F8GJ67 A0A5F8GJ67 PTHR24381:SF479 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 432 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000019077.2|UniProtKB=F7FNN5 F7FNN5 PTHR13069:SF36 ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 TRNA METHYLTRANSFERASE 9B-RELATED catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;methyltransferase activity#GO:0008168;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;tRNA methyltransferase activity#GO:0008175;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640 gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;RNA methylation#GO:0001510;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000023638.3|UniProtKB=F7ED84 F7ED84 PTHR24377:SF980 IP01015P-RELATED ZINC FINGER PROTEIN 420 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002737.4|UniProtKB=F7AZK5 F7AZK5 PTHR24300:SF368 CYTOCHROME P450 508A4-RELATED UNSPECIFIC MONOOXYGENASE tetrapyrrole binding#GO:0046906;binding#GO:0005488;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;response to chemical#GO:0042221 intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;oxygenase#PC00177 MONDO|Ensembl=ENSMODG00000013821.3|UniProtKB=F6SEZ4 F6SEZ4 IL1A PTHR10078:SF33 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-1 ALPHA molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125 response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of intracellular signal transduction#GO:1902533;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;positive regulation of cell adhesion#GO:0045785;positive regulation of cell communication#GO:0010647;response to external biotic stimulus#GO:0043207;response to bacterium#GO:0009617;positive regulation of lymphocyte proliferation#GO:0050671;inflammatory response#GO:0006954;cell communication#GO:0007154;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;positive regulation of cell-cell adhesion#GO:0022409;response to lipid#GO:0033993;regulation of T cell activation#GO:0050863;response to chemical#GO:0042221;positive regulation of T cell activation#GO:0050870;response to cytokine#GO:0034097;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;positive regulation of leukocyte activation#GO:0002696;regulation of MAPK cascade#GO:0043408;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of cell population proliferation#GO:0008284;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;regulation of lymphocyte activation#GO:0051249;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of T cell proliferation#GO:0042102;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of leukocyte proliferation#GO:0070665;regulation of response to stimulus#GO:0048583;defense response#GO:0006952;cellular response to biotic stimulus#GO:0071216;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of T cell proliferation#GO:0042129;regulation of cell communication#GO:0010646;cytokine-mediated signaling pathway#GO:0019221;positive regulation of lymphocyte activation#GO:0051251;regulation of cell population proliferation#GO:0042127;positive regulation of immune system process#GO:0002684;regulation of mononuclear cell proliferation#GO:0032944;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;cellular response to lipid#GO:0071396;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of mononuclear cell proliferation#GO:0032946;regulation of leukocyte proliferation#GO:0070663;response to lipopolysaccharide#GO:0032496;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to molecule of bacterial origin#GO:0002237;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083;interleukin superfamily#PC00128;intercellular signal molecule#PC00207 Interleukin signaling pathway#P00036>Interleukin#P00970;Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 MONDO|Ensembl=ENSMODG00000001370.4|UniProtKB=A0A5F8HI20 A0A5F8HI20 SPATA6 PTHR16435:SF3 SPERMATOGENESIS-ASSOCIATED PROTEIN 6 SPATA6 SPERMATOGENESIS-ASSOCIATED PROTEIN 6 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;myosin binding#GO:0017022 cilium organization#GO:0044782;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;gamete generation#GO:0007276;cell projection organization#GO:0030030;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;plasma membrane bounded cell projection assembly#GO:0120031;spermatogenesis#GO:0007283;developmental process#GO:0032502;male gamete generation#GO:0048232;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000007355.3|UniProtKB=F7ADT3 F7ADT3 MIS18BP1 PTHR16124:SF3 MIS18-BINDING PROTEIN 1 MIS18-BINDING PROTEIN 1 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775 MONDO|Ensembl=ENSMODG00000018862.4|UniProtKB=A0A5F8H4E4 A0A5F8H4E4 PI4KB PTHR10048:SF122 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE BETA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742 cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;anatomical structure development#GO:0048856;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;sensory organ development#GO:0007423;glycerophospholipid biosynthetic process#GO:0046474;developmental process#GO:0032502;lipid metabolic process#GO:0006629;organophosphate metabolic process#GO:0019637;inner ear development#GO:0048839;glycerolipid biosynthetic process#GO:0045017;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;biological regulation#GO:0065007;phosphatidylinositol phosphate biosynthetic process#GO:0046854;animal gross anatomical part developmental process#GO:0160108;ear development#GO:0043583;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;signaling#GO:0023052;metabolic process#GO:0008152;animal organ development#GO:0048513;signal transduction#GO:0007165;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650 membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 MONDO|Ensembl=ENSMODG00000019007.4|UniProtKB=A0A5F8GWW8 A0A5F8GWW8 PPP2R5D PTHR10257:SF89 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT DELTA ISOFORM phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;phosphatase activator activity#GO:0019211;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic sister chromatid cohesion#GO:0051177;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protein phosphatase#PC00195 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 MONDO|Ensembl=ENSMODG00000003745.4|UniProtKB=F7ECS2 F7ECS2 DDX49 PTHR24031:SF761 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX49-RELATED RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000002612.4|UniProtKB=A0A5F8H438 A0A5F8H438 GNPTAB PTHR24045:SF1 FAMILY NOT NAMED N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNITS ALPHA_BETA catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772 protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;protein localization to organelle#GO:0033365;protein localization to vacuole#GO:0072665;localization#GO:0051179;protein metabolic process#GO:0019538;vacuole organization#GO:0007033;glycoprotein biosynthetic process#GO:0009101;macromolecule localization#GO:0033036;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;lytic vacuole organization#GO:0080171;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein localization to lysosome#GO:0061462;cellular component organization#GO:0016043;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;lysosomal transport#GO:0007041;cellular localization#GO:0051641;protein transport#GO:0015031;organelle organization#GO:0006996;protein targeting to vacuole#GO:0006623;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lysosome organization#GO:0007040;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;carbohydrate derivative biosynthetic process#GO:1901137 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000011623.4|UniProtKB=F6U180 F6U180 DIPK1A PTHR21093:SF4 DIVERGENT PROTEIN KINASE DOMAIN 1C-RELATED DIVERGENT PROTEIN KINASE DOMAIN 1A MONDO|Ensembl=ENSMODG00000007705.4|UniProtKB=F7F9D0 F7F9D0 NDUFA10 PTHR10513:SF15 DEOXYNUCLEOSIDE KINASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;deoxynucleoside kinase activity#GO:0019136 oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904 respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000010191.2|UniProtKB=F6SU17 F6SU17 PTHR24068:SF177 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 2 catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein K63-linked ubiquitination#GO:0070534;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 MONDO|Ensembl=ENSMODG00000044011.1|UniProtKB=A0A5F8G3G4 A0A5F8G3G4 NPHP3 PTHR19871:SF36 BETA TRANSDUCIN-RELATED PROTEIN NEPHROCYSTIN-3 MONDO|Ensembl=ENSMODG00000016799.4|UniProtKB=F7FVT0 F7FVT0 ENTPD4 PTHR11782:SF29 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 4 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside diphosphate catabolic process#GO:0009134;ribonucleoside diphosphate metabolic process#GO:0009185;ribonucleoside diphosphate catabolic process#GO:0009191;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;nucleoside diphosphate metabolic process#GO:0009132;ribonucleotide metabolic process#GO:0009259;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;ribose phosphate metabolic process#GO:0019693;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 phosphatase#PC00181;nucleotide phosphatase#PC00173;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000017915.4|UniProtKB=F7F2Q7 F7F2Q7 GANC PTHR22762:SF60 ALPHA-GLUCOSIDASE NEUTRAL ALPHA-GLUCOSIDASE C hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;alpha-glucosidase activity#GO:0090599;glucosidase activity#GO:0015926;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058 glucosidase#PC00108 MONDO|Ensembl=ENSMODG00000051147.1|UniProtKB=A0A5F8H4I0 A0A5F8H4I0 IBA57 PTHR22602:SF0 IRON-SULFUR CLUSTER ASSEMBLY FACTOR CAF17/IBA57, MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY FACTOR IBA57, MITOCHONDRIAL intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 MONDO|Ensembl=ENSMODG00000015559.3|UniProtKB=F7AJD1 F7AJD1 PPP1CB PTHR11668:SF472 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE PP1-BETA CATALYTIC SUBUNIT protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 rhythmic process#GO:0048511;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;circadian rhythm#GO:0007623;circadian regulation of gene expression#GO:0032922;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of circadian rhythm#GO:0042752;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969;Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602 MONDO|Ensembl=ENSMODG00000014753.5|UniProtKB=F6YMG3 F6YMG3 GRHL1 PTHR11037:SF16 TRANSCRIPTION FACTOR CP2 GRAINYHEAD-LIKE PROTEIN 1 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000028011.2|UniProtKB=K7E213 K7E213 ZNF185 PTHR15468:SF2 ZNF185 ZINC FINGER PROTEIN 185 MONDO|Ensembl=ENSMODG00000036805.1|UniProtKB=A0A5F8HJS8 A0A5F8HJS8 PTHR11267:SF200 T-BOX PROTEIN-RELATED MGA, MAX DIMERIZATION PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell fate specification#GO:0001708;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 MONDO|Ensembl=ENSMODG00000049001.1|UniProtKB=A0A5F8HG63 A0A5F8HG63 ORAI3 PTHR31501:SF6 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 PROTEIN ORAI-3 calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261 establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 MONDO|Ensembl=ENSMODG00000007753.3|UniProtKB=F7BJE2 F7BJE2 SPC25 PTHR14281:SF0 KINETOCHORE PROTEIN SPC25-RELATED KINETOCHORE PROTEIN SPC25 cell cycle#GO:0007049;chromosome segregation#GO:0007059;cell cycle process#GO:0022402;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;kinetochore#GO:0000776;membraneless organelle#GO:0043228;outer kinetochore#GO:0000940;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000019661.4|UniProtKB=F7E635 F7E635 NLN PTHR11804:SF44 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED NEUROLYSIN, MITOCHONDRIAL catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000021196.3|UniProtKB=F6XE54 F6XE54 KCNE4 PTHR15282:SF9 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 4 monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;protein binding#GO:0005515;potassium channel regulator activity#GO:0015459;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;binding#GO:0005488;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel regulator activity#GO:0016247;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter binding#GO:0044325;transporter regulator activity#GO:0141108;potassium channel activity#GO:0005267;molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ion channel regulator activity#GO:0099106;passive transmembrane transporter activity#GO:0022803 export from cell#GO:0140352;heart process#GO:0003015;regulation of biological process#GO:0050789;action potential#GO:0001508;muscle system process#GO:0003012;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;regulation of multicellular organismal process#GO:0051239;monoatomic cation transmembrane transport#GO:0098655;cardiac muscle cell action potential involved in contraction#GO:0086002;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;regulation of heart contraction#GO:0008016;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;actin-mediated cell contraction#GO:0070252;localization#GO:0051179;monoatomic cation transport#GO:0006812;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;potassium ion transport#GO:0006813;blood circulation#GO:0008015;actin filament-based movement#GO:0030048;heart contraction#GO:0060047;system process#GO:0003008;establishment of localization#GO:0051234;cardiac muscle cell contraction#GO:0086003;transport#GO:0006810;muscle contraction#GO:0006936;regulation of system process#GO:0044057 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000014091.4|UniProtKB=A0A5F8GJS3 A0A5F8GJS3 PTHR11562:SF51 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A2 monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;response to chemical#GO:0042221;response to metal ion#GO:0010038;transport#GO:0006810;establishment of localization#GO:0051234;metal ion transport#GO:0030001;response to stimulus#GO:0050896;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000018998.4|UniProtKB=F7ANE7 F7ANE7 PURG PTHR12611:SF3 PUR-TRANSCRIPTIONAL ACTIVATOR PURINE-RICH ELEMENT-BINDING PROTEIN GAMMA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000009154.4|UniProtKB=F7B0L6 F7B0L6 G6PD PTHR23429:SF23 GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE glucose-6-phosphate dehydrogenase activity#GO:0004345;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 nucleobase-containing small molecule metabolic process#GO:0055086;glucose metabolic process#GO:0006006;generation of precursor metabolites and energy#GO:0006091;pentose-phosphate shunt, oxidative branch#GO:0009051;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;pentose-phosphate shunt#GO:0006098;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000023048.3|UniProtKB=F7DCN0 F7DCN0 PTHR24377:SF980 IP01015P-RELATED ZINC FINGER PROTEIN 420 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000041626.1|UniProtKB=A0A5F8H5C5 A0A5F8H5C5 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000006937.4|UniProtKB=F6RGH2 F6RGH2 GDAP1 PTHR44188:SF3 GDAP1, ISOFORM A GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 1 cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;mitochondrion organization#GO:0007005;organelle fusion#GO:0048284;mitochondrial fission#GO:0000266;cellular process#GO:0009987;mitochondrial fusion#GO:0008053;organelle organization#GO:0006996;cellular component organization#GO:0016043 organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000017797.4|UniProtKB=F7CFL7 F7CFL7 MAP1A PTHR13843:SF6 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 1A binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 axonogenesis#GO:0007409;neuron development#GO:0048666;dendrite development#GO:0016358;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;regulation of microtubule cytoskeleton organization#GO:0070507;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;regulation of microtubule-based process#GO:0032886;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of supramolecular fiber organization#GO:1902903;neurogenesis#GO:0022008;regulation of microtubule polymerization or depolymerization#GO:0031110;regulation of protein depolymerization#GO:1901879;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon development#GO:0061564 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell body#GO:0044297;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;neuron projection#GO:0043005;cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000015116.3|UniProtKB=F7ELZ5 F7ELZ5 FGF12 PTHR11486:SF17 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 12 fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;ion channel regulator activity#GO:0099106;protein binding#GO:0005515;channel regulator activity#GO:0016247;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;transporter regulator activity#GO:0141108 positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;nervous system development#GO:0007399;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;response to fibroblast growth factor#GO:0071774;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 MONDO|Ensembl=ENSMODG00000013433.4|UniProtKB=F7GIN1 F7GIN1 KLHL24 PTHR24412:SF215 KELCH PROTEIN KELCH-LIKE PROTEIN 24 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013488.4|UniProtKB=F7F8U5 F7F8U5 PRR16 PTHR15917:SF0 FAMILY NOT NAMED PROTEIN LARGEN cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of protein metabolic process#GO:0051247;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of translation#GO:0045727;regulation of cell size#GO:0008361;regulation of biological quality#GO:0065008;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of anatomical structure size#GO:0090066;post-transcriptional regulation of gene expression#GO:0010608;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468 MONDO|Ensembl=ENSMODG00000009266.4|UniProtKB=F7DA21 F7DA21 GRK5 PTHR24355:SF27 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 5 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK5#P05940;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741 MONDO|Ensembl=ENSMODG00000014104.4|UniProtKB=F6QIV3 F6QIV3 SYNGAP1 PTHR10194:SF25 RAS GTPASE-ACTIVATING PROTEINS RAS_RAP GTPASE-ACTIVATING PROTEIN SYNGAP GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000009426.4|UniProtKB=F7BLB6 F7BLB6 PPP3CC PTHR45673:SF2 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT GAMMA ISOFORM binding#GO:0005488;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;protein binding#GO:0005515;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;calmodulin binding#GO:0005516;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;calcineurin-mediated signaling#GO:0097720;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722;cell communication#GO:0007154 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein phosphatase#PC00195 B cell activation#P00010>Calcineurin#P00386;Wnt signaling pathway#P00057>Calcineurin#P01446;T cell activation#P00053>Calcineurin#P01315 MONDO|Ensembl=ENSMODG00000008689.3|UniProtKB=A0A5F8G1W6 A0A5F8G1W6 LIPC PTHR11610:SF2 LIPASE HEPATIC TRIACYLGLYCEROL LIPASE protein binding#GO:0005515;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;binding#GO:0005488 catabolic process#GO:0009056;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 Triacylglycerol metabolism#P02782>Triacylglycerol lipase#P03205 MONDO|Ensembl=ENSMODG00000004397.4|UniProtKB=F6SVM2 F6SVM2 GLTP PTHR10219:SF97 GLYCOLIPID TRANSFER PROTEIN-RELATED GLYCOLIPID TRANSFER PROTEIN phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;ion binding#GO:0043167;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phospholipid binding#GO:0005543;transporter activity#GO:0005215 transport#GO:0006810;lipid localization#GO:0010876;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;membrane organization#GO:0061024;ceramide transport#GO:0035627;lipid transport#GO:0006869 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cytosol#GO:0005829 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000036564.1|UniProtKB=A0A5F8HKE7 A0A5F8HKE7 PTHR12850:SF5 40S RIBOSOMAL PROTEIN S25 SMALL RIBOSOMAL SUBUNIT PROTEIN ES25 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000007600.4|UniProtKB=A0A5F8HCT1 A0A5F8HCT1 RAB6A PTHR24073:SF1089 DRAB5-RELATED RAS-RELATED PROTEIN RAB-6A-RELATED hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 protein localization to membrane#GO:0072657;intra-Golgi vesicle-mediated transport#GO:0006891;protein localization to organelle#GO:0033365;cytosolic transport#GO:0016482;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000013375.4|UniProtKB=F7DTA2 F7DTA2 DDX6 PTHR47960:SF17 DEAD-BOX ATP-DEPENDENT RNA HELICASE 50 ATP-DEPENDENT RNA HELICASE DDX6-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 organelle assembly#GO:0070925;negative regulation of translation#GO:0017148;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;negative regulation of biological process#GO:0048519;P-body assembly#GO:0033962;regulation of biological process#GO:0050789;cytoplasmic stress granule assembly#GO:0034063;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular component biogenesis#GO:0044085;regulation of translation#GO:0006417;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;cellular component assembly#GO:0022607;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;P-body#GO:0000932;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000003609.4|UniProtKB=F7E4S5 F7E4S5 NRL PTHR10129:SF24 TRANSCRIPTION FACTOR MAF NEURAL RETINA-SPECIFIC LEUCINE ZIPPER PROTEIN RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;sensory system development#GO:0048880;nervous system development#GO:0007399;retina development in camera-type eye#GO:0060041;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;eye development#GO:0001654;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell development#GO:0048468;sensory organ morphogenesis#GO:0090596;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;sensory organ development#GO:0007423;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of metabolic process#GO:0019222;camera-type eye morphogenesis#GO:0048593;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;camera-type eye development#GO:0043010;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;visual system development#GO:0150063;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000023928.2|UniProtKB=F7FLN7 F7FLN7 PTHR46722:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7 HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7 HOMOLOG positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;biological regulation#GO:0065007 outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial outer membrane translocase complex#GO:0005742;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000009668.3|UniProtKB=F6SHR7 F6SHR7 GPX2 PTHR11592:SF36 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824 cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950 peroxidase#PC00180;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000006802.3|UniProtKB=F6PGY4 F6PGY4 PTHR10057:SF23 PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR TRANSLOCATOR PROTEIN membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000015178.4|UniProtKB=A0A5F8GEQ7 A0A5F8GEQ7 MOSPD1 PTHR34441:SF2 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 MONDO|Ensembl=ENSMODG00000003402.4|UniProtKB=A0A5F8H2L2 A0A5F8H2L2 TCF25 PTHR22684:SF0 NULP1-RELATED RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT TCF25 protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000015546.4|UniProtKB=A0A5F8HLX9 A0A5F8HLX9 MARCHF4 PTHR46053:SF3 E3 UBIQUITIN-PROTEIN LIGASE MARCH4-LIKE E3 UBIQUITIN-PROTEIN LIGASE MARCHF4 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000011953.3|UniProtKB=A0A5F8HI78 A0A5F8HI78 FAM167A PTHR32289:SF3 PROTEIN FAM167A PROTEIN FAM167A MONDO|Ensembl=ENSMODG00000037823.1|UniProtKB=A0A5F8GUP7 A0A5F8GUP7 CXCL16 PTHR14385:SF0 CXC CHEMOKINE LIGAND C-X-C MOTIF CHEMOKINE 16 binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;low-density lipoprotein particle receptor activity#GO:0005041;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cargo receptor activity#GO:0038024 lymphocyte migration#GO:0072676;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cell migration#GO:0030335;cellular process#GO:0009987;response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;leukocyte chemotaxis#GO:0030595;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;locomotion#GO:0040011;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;mononuclear cell migration#GO:0071674;chemotaxis#GO:0006935;regulation of cell motility#GO:2000145;cell chemotaxis#GO:0060326 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074;cytokine#PC00083 MONDO|Ensembl=ENSMODG00000012098.3|UniProtKB=F7G4K2 F7G4K2 DLX3 PTHR24327:SF28 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-3 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;skeletal system development#GO:0001501;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;embryo development ending in birth or egg hatching#GO:0009792 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000006420.4|UniProtKB=A0A5F8GI05 A0A5F8GI05 KIF26B PTHR21608:SF8 KINESIN-LIKE PROTEIN CG14535 KINESIN-LIKE PROTEIN KIF26B protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 animal organ development#GO:0048513;developmental growth#GO:0048589;multicellular organism development#GO:0007275;morphogenesis of an epithelium#GO:0002009;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of neuron migration#GO:2001222;growth#GO:0040007;regulation of cell migration#GO:0030334;developmental process#GO:0032502;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;regulation of locomotion#GO:0040012;tube development#GO:0035295;biological regulation#GO:0065007;kidney development#GO:0001822;renal system development#GO:0072001;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;tissue morphogenesis#GO:0048729;developmental growth involved in morphogenesis#GO:0060560;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;tube morphogenesis#GO:0035239;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 MONDO|Ensembl=ENSMODG00000011603.4|UniProtKB=A0A5F8GE40 A0A5F8GE40 ATG4A PTHR22624:SF35 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4A hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein-phosphatidylethanolamide deconjugating activity#GO:0019786;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197 catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein metabolic process#GO:0019538;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;autophagosome assembly#GO:0000045;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000036981.1|UniProtKB=A0A5F8GHH8 A0A5F8GHH8 LOC103099141 PTHR24377:SF980 IP01015P-RELATED ZINC FINGER PROTEIN 420 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000011848.3|UniProtKB=F7GDQ1 F7GDQ1 PTHR10533:SF14 NEUROPEPTIDE Y/PANCREATIC HORMONE/PEPTIDE YY PEPTIDE YY-RELATED G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;neuropeptide receptor binding#GO:0071855;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;neuropeptide hormone activity#GO:0005184;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515 multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;feeding behavior#GO:0007631;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000006698.3|UniProtKB=A0A5F8H110 A0A5F8H110 UVRAG PTHR15157:SF5 UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN phosphatidylinositol phosphate biosynthetic process#GO:0046854;process utilizing autophagic mechanism#GO:0061919;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;phospholipid biosynthetic process#GO:0008654;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;autophagy#GO:0006914;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;macroautophagy#GO:0016236;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endosome#GO:0005768;phosphatidylinositol 3-kinase complex, class III#GO:0035032;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;lytic vacuole#GO:0000323;extrinsic component of membrane#GO:0019898;transferase complex#GO:1990234;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000017928.4|UniProtKB=A0A5F8GXT9 A0A5F8GXT9 VPS39 PTHR12894:SF49 CNH DOMAIN CONTAINING VAM6_VPS39-LIKE PROTEIN enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515;small GTPase binding#GO:0031267 metabolic process#GO:0008152;autophagosome maturation#GO:0097352;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;autophagy#GO:0006914;cellular process#GO:0009987;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;macroautophagy#GO:0016236;vacuole fusion#GO:0097576;localization#GO:0051179;cellular component disassembly#GO:0022411;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;cellular component organization#GO:0016043;catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;vesicle tethering complex#GO:0099023;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosomal membrane#GO:0005765;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000050255.1|UniProtKB=A0A5F8HK61 A0A5F8HK61 TOLLIP PTHR16461:SF5 TOLL-INTERACTING PROTEIN TOLL-INTERACTING PROTEIN enzyme binding#GO:0019899;ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 Toll receptor signaling pathway#P00054>Tollip#P01379 MONDO|Ensembl=ENSMODG00000022736.3|UniProtKB=H9H6P6 H9H6P6 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000006556.4|UniProtKB=F7BUX5 F7BUX5 PLPP2 PTHR10165:SF25 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 2 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154;dephosphorylation#GO:0016311;signal transduction#GO:0007165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;lipid modification#GO:0030258 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000017199.4|UniProtKB=F6XFM5 F6XFM5 REEP3 PTHR12300:SF39 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 3 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;endoplasmic reticulum tubular network organization#GO:0071786;cellular component organization or biogenesis#GO:0071840 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic microtubule#GO:0005881;microtubule#GO:0005874;organelle subcompartment#GO:0031984;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;supramolecular complex#GO:0099080;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;endoplasmic reticulum tubular network#GO:0071782;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;cytoskeleton#GO:0005856;endoplasmic reticulum#GO:0005783 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000037339.1|UniProtKB=A0A5F8HKH6 A0A5F8HKH6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000007146.4|UniProtKB=F6RYH6 F6RYH6 KCTD2 PTHR14958:SF22 POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD2 protein binding#GO:0005515;binding#GO:0005488 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000019359.4|UniProtKB=F6X920 F6X920 PTHR23226:SF461 ZINC FINGER AND SCAN DOMAIN-CONTAINING OOCYTE ZINC FINGER PROTEIN XLCOF8.4-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000023085.2|UniProtKB=A0A5F8HGZ2 A0A5F8HGZ2 B3GNT9 PTHR11214:SF91 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 9 glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824 aminoglycan biosynthetic process#GO:0006023;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000045623.1|UniProtKB=A0A5F8GWT4 A0A5F8GWT4 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000019304.4|UniProtKB=F6RYL5 F6RYL5 HPSE PTHR46145:SF3 HEPARANASE HEPARANASE cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;animal gross anatomical part developmental process#GO:0160108;wound healing#GO:0042060;system development#GO:0048731;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;cell-substrate adhesion#GO:0031589;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;circulatory system development#GO:0072359;response to stimulus#GO:0050896;developmental process#GO:0032502;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;cellular process#GO:0009987;response to wounding#GO:0009611;response to stress#GO:0006950;tube development#GO:0035295;multicellular organismal process#GO:0032501 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110 MONDO|Ensembl=ENSMODG00000006179.4|UniProtKB=F7B4X9 F7B4X9 FCF1 PTHR12416:SF2 RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RRNA-PROCESSING PROTEIN FCF1 HOMOLOG primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000040300.1|UniProtKB=A0A5F8GX32 A0A5F8GX32 RWDD2A PTHR15955:SF3 RWD DOMAIN CONTAINING PROTEIN 2 RWD DOMAIN-CONTAINING PROTEIN 2A ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000003685.4|UniProtKB=A0A5F8G4H5 A0A5F8G4H5 LOC103101397 PTHR15756:SF6 LR8/HCA112 TRANSMEMBRANE PROTEIN 176A MONDO|Ensembl=ENSMODG00000011068.3|UniProtKB=F7DSL6 F7DSL6 DISP3 PTHR46687:SF1 PROTEIN DISPATCHED HOMOLOG 3 PROTEIN DISPATCHED HOMOLOG 3 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000006593.2|UniProtKB=F7AKS2 F7AKS2 TTL PTHR46570:SF1 TUBULIN--TYROSINE LIGASE TUBULIN--TYROSINE LIGASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a protein#GO:0140096;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;spindle microtubule#GO:0005876;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874 MONDO|Ensembl=ENSMODG00000013553.3|UniProtKB=A0A5F8GXF1 A0A5F8GXF1 KCTD20 PTHR21637:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 10-RELATED BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD20 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000011524.4|UniProtKB=A0A5F8GFT8 A0A5F8GFT8 PTHR11668:SF204 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;regulation of circadian rhythm#GO:0042752;cellular process#GO:0009987 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602;Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969 MONDO|Ensembl=ENSMODG00000045854.1|UniProtKB=F7C584 F7C584 PTHR26453:SF76 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13H1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000023061.3|UniProtKB=F6Z0J5 F6Z0J5 PTHR23232:SF140 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 11-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000018272.4|UniProtKB=F6Q714 F6Q714 PTHR15673:SF2 IQ CALMODULIN-BINDING MOTIF CONTAINING PROTEIN 1 IQ CALMODULIN-BINDING MOTIF-CONTAINING PROTEIN 1 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929 MONDO|Ensembl=ENSMODG00000015347.2|UniProtKB=F6WYC0 F6WYC0 AP5S1 PTHR16120:SF0 AP-5 COMPLEX SUBUNIT SIGMA-1 AP-5 COMPLEX SUBUNIT SIGMA-1 intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 intracellular organelle#GO:0043229;endosome#GO:0005768;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole#GO:0000323;AP-type membrane coat adaptor complex#GO:0030119;cytosol#GO:0005829;membrane#GO:0016020;protein-containing complex#GO:0032991;late endosome#GO:0005770;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000047525.1|UniProtKB=A0A5F8HLE0 A0A5F8HLE0 PTHR22918:SF5 SEMINAL PLASMA PROTEIN BINDER OF SPERM PROTEIN HOMOLOG 2 cellular process#GO:0009987;developmental maturation#GO:0021700;male gamete generation#GO:0048232;sperm capacitation#GO:0048240;spermatogenesis#GO:0007283;developmental process#GO:0032502;cell maturation#GO:0048469;cellular developmental process#GO:0048869;developmental process involved in reproduction#GO:0003006;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;cell differentiation#GO:0030154;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;reproductive process#GO:0022414;spermatid differentiation#GO:0048515;sexual reproduction#GO:0019953;spermatid development#GO:0007286;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000038620.1|UniProtKB=A0A5F8H390 A0A5F8H390 PTHR31402:SF2 UPF0711 PROTEIN C18ORF21 RIBONUCLEASE MRP PROTEIN SUBUNIT P24 MONDO|Ensembl=ENSMODG00000020578.4|UniProtKB=H9H7M2 H9H7M2 PICK1 PTHR12141:SF1 ARFAPTIN-RELATED PRKCA-BINDING PROTEIN molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 localization#GO:0051179;localization within membrane#GO:0051668;synapse organization#GO:0050808;postsynapse organization#GO:0099173;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of supramolecular fiber organization#GO:1902903;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;regulation of actin filament-based process#GO:0032970;intracellular transport#GO:0046907;regulation of actin nucleation#GO:0051125;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;positive regulation of endocytosis#GO:0045807;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;macromolecule localization#GO:0033036;protein transport#GO:0015031;cellular localization#GO:0051641;receptor clustering#GO:0043113;positive regulation of cellular component organization#GO:0051130;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;neuron projection organization#GO:0106027;cell projection organization#GO:0030030;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;regulation of endocytosis#GO:0030100;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;dendritic spine organization#GO:0097061;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 cell junction#GO:0030054;secretory vesicle#GO:0099503;presynapse#GO:0098793;neuron projection#GO:0043005;trans-Golgi network membrane#GO:0032588;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;organelle subcompartment#GO:0031984;intracellular vesicle#GO:0097708;postsynapse#GO:0098794;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;postsynaptic specialization#GO:0099572;transport vesicle#GO:0030133;neuron to neuron synapse#GO:0098984;endomembrane system#GO:0012505;postsynaptic density#GO:0014069;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;synaptic vesicle#GO:0008021;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231 vesicle coat protein#PC00235 Ionotropic glutamate receptor pathway#P00037>PICK#P01012 MONDO|Ensembl=ENSMODG00000049736.1|UniProtKB=A0A5F8GE33 A0A5F8GE33 PTHR12307:SF7 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3G enzyme binding#GO:0019899;polysaccharide binding#GO:0030247;phosphatase binding#GO:0019902;binding#GO:0005488;protein phosphatase binding#GO:0019903;carbohydrate binding#GO:0030246;protein binding#GO:0005515 regulation of carbohydrate biosynthetic process#GO:0043255;biological regulation#GO:0065007;regulation of polysaccharide metabolic process#GO:0032881;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of glycogen biosynthetic process#GO:0005979;regulation of carbohydrate metabolic process#GO:0006109 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000027311.2|UniProtKB=K7E5D9 K7E5D9 LOC100019770 PTHR16008:SF6 F-BOX ONLY PROTEIN 4 SI:DKEY-12E7.1 cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461 MONDO|Ensembl=ENSMODG00000051253.1|UniProtKB=A0A5F8GRZ7 A0A5F8GRZ7 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000009249.4|UniProtKB=F7DVY2 F7DVY2 CASTOR1 PTHR31131:SF3 CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE CYTOSOLIC ARGININE SENSOR FOR MTORC1 SUBUNIT 1 amino acid binding#GO:0016597;ion binding#GO:0043167;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;organic acid binding#GO:0043177;cation binding#GO:0043169 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of TORC1 signaling#GO:1904262;regulation of TORC1 signaling#GO:1903432;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;response to acid chemical#GO:0001101;cellular response to oxygen-containing compound#GO:1901701;negative regulation of response to stimulus#GO:0048585;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;response to nitrogen compound#GO:1901698;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000019559.3|UniProtKB=F6UCP1 F6UCP1 NSFL1C PTHR23333:SF24 UBX DOMAIN CONTAINING PROTEIN NSFL1 COFACTOR P47 ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;cytoskeleton organization#GO:0007010;regulation of cell cycle process#GO:0010564;proteasomal protein catabolic process#GO:0010498;positive regulation of cell cycle#GO:0045787;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;establishment or maintenance of cell polarity#GO:0007163;spindle localization#GO:0051653;cellular localization#GO:0051641;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;cell cycle process#GO:0022402;cellular component organization#GO:0016043;regulation of cell cycle#GO:0051726;establishment of organelle localization#GO:0051656;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;mitotic cell cycle process#GO:1903047;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;positive regulation of cellular process#GO:0048522;establishment of spindle localization#GO:0051293;biological regulation#GO:0065007;organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;establishment of cell polarity#GO:0030010;cell cycle#GO:0007049;primary metabolic process#GO:0044238;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;catabolic process#GO:0009056;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000001130.5|UniProtKB=A0A5F8G415 A0A5F8G415 KDM4B PTHR10694:SF145 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4B histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;protein demethylase activity#GO:0140457;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000004880.4|UniProtKB=F7C2R3 F7C2R3 MRTFB PTHR22793:SF5 MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED MYOCARDIN-RELATED TRANSCRIPTION FACTOR B cellular process#GO:0009987;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000013486.4|UniProtKB=F7F917 F7F917 PAF1 PTHR23188:SF12 RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG binding#GO:0005488;RNA polymerase binding#GO:0070063;chromatin binding#GO:0003682;enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000047715.1|UniProtKB=A0A5F8GQ01 A0A5F8GQ01 MDFI PTHR15304:SF1 MYOD FAMILY INHIBITOR MYOD FAMILY INHIBITOR regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of JNK cascade#GO:0046328;regulation of biosynthetic process#GO:0009889;regulation of MAPK cascade#GO:0043408;negative regulation of RNA biosynthetic process#GO:1902679;regulation of response to stimulus#GO:0048583;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000000771.1|UniProtKB=F6SSS3 F6SSS3 GNG12 PTHR13809:SF9 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-12 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;side of membrane#GO:0098552;extrinsic component of plasma membrane#GO:0019897 heterotrimeric G-protein#PC00117 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Wnt signaling pathway#P00057>Ggamma#P01465;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Enkephalin release#P05913>G-Protein (s)#P05977;Enkephalin release#P05913>G-Protein (i)#P05974;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430 MONDO|Ensembl=ENSMODG00000012353.3|UniProtKB=K7E526 K7E526 PTHR11470:SF2 KAPPA CASEIN KAPPA-CASEIN biological regulation#GO:0065007;regulation of body fluid levels#GO:0050878;regulation of protein stability#GO:0031647;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008;secretion#GO:0046903;establishment of localization#GO:0051234;animal organ development#GO:0048513;anatomical structure development#GO:0048856;localization#GO:0051179;transport#GO:0006810;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 storage protein#PC00210 MONDO|Ensembl=ENSMODG00000007144.4|UniProtKB=A0A5F8GA28 A0A5F8GA28 SBSPON PTHR20920:SF2 RPE-SPONDIN SOMATOMEDIN-B AND THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000016940.3|UniProtKB=F6VMI9 F6VMI9 POU1F1 PTHR11636:SF84 POU DOMAIN PITUITARY-SPECIFIC POSITIVE TRANSCRIPTION FACTOR 1 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000006506.2|UniProtKB=F7EK12 F7EK12 KLK9 PTHR24271:SF57 KALLIKREIN-RELATED KALLIKREIN-9 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000001799.4|UniProtKB=F6WI83 F6WI83 ZNF668 PTHR24376:SF70 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 668 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000025673.3|UniProtKB=F6U0Z2 F6U0Z2 PTHR11481:SF5 IMMUNOGLOBULIN FC RECEPTOR PLATELET ENDOTHELIAL CELL ADHESION MOLECULE molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 immune system process#GO:0002376;cell surface receptor signaling pathway#GO:0007166;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-cell adhesion#GO:0098609;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;immune response#GO:0006955;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000014679.3|UniProtKB=F7E7I8 F7E7I8 LOC100023625 PTHR24250:SF65 CHYMOTRYPSIN-RELATED CHYMOTRYPSINOGEN B catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 serine protease#PC00203;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000008614.4|UniProtKB=F6PH95 F6PH95 NUP58 PTHR13437:SF2 NUCLEOPORIN P58/P45 NUCLEOPORIN-LIKE PROTEIN 1 NUCLEOPORIN P58_P45 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 intracellular transport#GO:0046907;nucleocytoplasmic transport#GO:0006913;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;nuclear transport#GO:0051169;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 transporter#PC00227 MONDO|Ensembl=ENSMODG00000019044.4|UniProtKB=F7AYW6 F7AYW6 FGL1 PTHR19143:SF263 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN-LIKE PROTEIN 1 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of T cell activation#GO:0050863;regulation of cell adhesion#GO:0030155;negative regulation of cell-cell adhesion#GO:0022408;negative regulation of cell adhesion#GO:0007162;negative regulation of cell activation#GO:0050866;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of lymphocyte activation#GO:0051249;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;regulation of immune response#GO:0050776;negative regulation of T cell activation#GO:0050868 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000003443.4|UniProtKB=A0A5F8G3Q2 A0A5F8G3Q2 CCDC57 PTHR46725:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 57 COILED-COIL DOMAIN-CONTAINING PROTEIN 57 regulation of cellular process#GO:0050794;cell cycle#GO:0007049;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;centriole replication#GO:0007099;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;microtubule polymerization or depolymerization#GO:0031109;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;positive regulation of mitotic cell cycle#GO:0045931;microtubule polymerization#GO:0046785;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;regulation of cell cycle#GO:0051726;membraneless organelle assembly#GO:0140694;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule nucleation#GO:0007020;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cilium organization#GO:0044782;cellular component assembly#GO:0022607;positive regulation of cell cycle#GO:0045787;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;microtubule organizing center organization#GO:0031023 cytoskeleton#GO:0005856;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;intracellular organelle#GO:0043229;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cellular anatomical structure#GO:0110165;organelle#GO:0043226;centriolar satellite#GO:0034451 MONDO|Ensembl=ENSMODG00000029407.2|UniProtKB=K7DZ88 K7DZ88 PTHR11208:SF45 RNA-BINDING PROTEIN RELATED SPLICING FACTOR 1 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000025574.2|UniProtKB=F6U2S4 F6U2S4 PTHR11085:SF6 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2 catalytic activity, acting on a protein#GO:0140096;NAD-dependent protein lysine deacetylase activity#GO:0034979;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;transferase activity#GO:0016740;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993;acyltransferase activity#GO:0016746 nucleolus organization#GO:0007000;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;nucleus organization#GO:0006997;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular component assembly#GO:0022607;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000038495.1|UniProtKB=A0A5F8GP02 A0A5F8GP02 PTHR47977:SF72 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-44 hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;transport#GO:0006810 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000012949.3|UniProtKB=F7DWP5 F7DWP5 PTHR11913:SF15 COFILIN-RELATED COFILIN-2 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;actin filament depolymerization#GO:0030042;actin cytoskeleton organization#GO:0030036;protein depolymerization#GO:0051261;cytoskeleton organization#GO:0007010;protein-containing complex disassembly#GO:0032984;actin filament-based process#GO:0030029;cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Cofilin#P00508 MONDO|Ensembl=ENSMODG00000010886.4|UniProtKB=F7FJG2 F7FJG2 STMND1 PTHR10104:SF20 STATHMIN STATHMIN DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488 microtubule polymerization or depolymerization#GO:0031109;protein depolymerization#GO:0051261;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of microtubule polymerization or depolymerization#GO:0031110;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;protein-containing complex disassembly#GO:0032984;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule-based process#GO:0032886;supramolecular fiber organization#GO:0097435;system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;nervous system development#GO:0007399;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;microtubule depolymerization#GO:0007019;neuron differentiation#GO:0030182;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;cellular component disassembly#GO:0022411 neuron projection#GO:0043005;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000012077.4|UniProtKB=A0A5F8GEL6 A0A5F8GEL6 CYB561D2 PTHR15422:SF21 OS05G0565100 PROTEIN TRANSMEMBRANE REDUCTASE CYB561D2 oxidoreductase activity#GO:0016491;tetrapyrrole binding#GO:0046906;binding#GO:0005488;catalytic activity#GO:0003824;heme binding#GO:0020037 chemical homeostasis#GO:0048878;carbohydrate homeostasis#GO:0033500;homeostatic process#GO:0042592 MONDO|Ensembl=ENSMODG00000014682.4|UniProtKB=F7DNQ9 F7DNQ9 LOC100013399 PTHR24291:SF198 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4F11 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000002412.4|UniProtKB=F7EH60 F7EH60 TESK2 PTHR46485:SF6 LIM DOMAIN KINASE 1 DUAL SPECIFICITY TESTIS-SPECIFIC PROTEIN KINASE 2 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000001681.5|UniProtKB=F6SQ13 F6SQ13 MAP1B PTHR13843:SF5 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 1B protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;dendrite development#GO:0016358;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;regulation of protein-containing complex disassembly#GO:0043244;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular process#GO:0009987;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;regulation of microtubule-based process#GO:0032886;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;system development#GO:0048731;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of protein depolymerization#GO:1901879;neurogenesis#GO:0022008;regulation of microtubule polymerization or depolymerization#GO:0031110;axon development#GO:0061564;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007 microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;cell body#GO:0044297;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000043598.1|UniProtKB=A0A5F8GJK7 A0A5F8GJK7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000009764.3|UniProtKB=F6TFM2 F6TFM2 RFC3 PTHR11669:SF1 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 3 catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;replication fork#GO:0005657;nucleus#GO:0005634 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 MONDO|Ensembl=ENSMODG00000024626.1|UniProtKB=F6Q9P6 F6Q9P6 PTHR10965:SF0 60S RIBOSOMAL PROTEIN L38 LARGE RIBOSOMAL SUBUNIT PROTEIN EL38 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000032250.2|UniProtKB=A0A5F8G5S1 A0A5F8G5S1 PTHR37862:SF3 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 20 UBZ2-TYPE DOMAIN-CONTAINING PROTEIN intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;Fanconi anaemia nuclear complex#GO:0043240;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000017755.4|UniProtKB=F7E507 F7E507 ELL3 PTHR23288:SF18 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;snRNA transcription#GO:0009301;regulation of DNA-templated transcription elongation#GO:0032784;nucleic acid biosynthetic process#GO:0141187;regulation of transcription elongation by RNA polymerase II#GO:0034243;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;snRNA metabolic process#GO:0016073;regulation of RNA metabolic process#GO:0051252 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000009701.3|UniProtKB=F6YB33 F6YB33 FNTB PTHR11774:SF6 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT PROTEIN FARNESYLTRANSFERASE SUBUNIT BETA prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 acyltransferase#PC00042;transferase#PC00220 MONDO|Ensembl=ENSMODG00000018153.3|UniProtKB=A0A5F8HIX8 A0A5F8HIX8 LRRC23 PTHR18849:SF3 LEUCINE RICH REPEAT PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 23 MONDO|Ensembl=ENSMODG00000000814.2|UniProtKB=F6S9P8 F6S9P8 PTHR19282:SF163 TETRASPANIN CD9 ANTIGEN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010102.5|UniProtKB=A0A5F8HCH8 A0A5F8HCH8 TANC2 PTHR24166:SF21 ROLLING PEBBLES, ISOFORM B PROTEIN TANC2 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 regulation of neuron projection development#GO:0010975;regulation of biological process#GO:0050789;regulation of postsynapse organization#GO:0099175;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of cell projection organization#GO:0031344;regulation of dendritic spine morphogenesis#GO:0061001;regulation of synapse organization#GO:0050807;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of synapse structure or activity#GO:0050803;regulation of anatomical structure morphogenesis#GO:0022603;regulation of biological quality#GO:0065008 cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794;neuron projection#GO:0043005;dendritic spine#GO:0043197 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000010958.3|UniProtKB=A0A5F8HGA2 A0A5F8HGA2 MAPT PTHR11501:SF14 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN TAU tubulin binding#GO:0015631;enzyme inhibitor activity#GO:0004857;cytoskeletal protein binding#GO:0008092;molecular function regulator activity#GO:0098772;binding#GO:0005488;microtubule binding#GO:0008017;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678 cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of microtubule-based movement#GO:0060632;generation of neurons#GO:0048699;regulation of microtubule-based process#GO:0032886;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;axon#GO:0030424 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000009430.4|UniProtKB=F7BKS9 F7BKS9 CALML4 PTHR23050:SF169 CALCIUM BINDING PROTEIN CALMODULIN-LIKE PROTEIN 4 calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000006782.3|UniProtKB=F7BTD1 F7BTD1 COG7 PTHR21443:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7 Golgi organization#GO:0007030;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;protein localization to organelle#GO:0033365;protein localization to Golgi apparatus#GO:0034067;intracellular protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular localization#GO:0051641 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;COG complex#GO:0017119;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000001929.4|UniProtKB=F6W0Q1 F6W0Q1 ANXA13 PTHR10502:SF175 ANNEXIN ANNEXIN A13 small molecule binding#GO:0036094;binding#GO:0005488;phospholipid binding#GO:0005543;anion binding#GO:0043168;ion binding#GO:0043167;lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786 nucleus#GO:0005634;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000014979.4|UniProtKB=F7CGC3 F7CGC3 LOC100025543 PTHR11412:SF86 MACROGLOBULIN / COMPLEMENT COMPLEMENT C4-A-RELATED molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488 immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;catalytic complex#GO:1902494;extracellular protein-containing complex#GO:0140392 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000015924.3|UniProtKB=F6ZQS0 F6ZQS0 MLST8 PTHR19842:SF0 G BETA-LIKE PROTEIN GBL TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of actin filament-based process#GO:0032970;TOR signaling#GO:0031929;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 intracellular protein-containing complex#GO:0140535;TOR complex#GO:0038201;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000014615.4|UniProtKB=F6ZE05 F6ZE05 C4H11orf65 PTHR33504:SF2 NADH DEHYDROGENASE (UBIQUINONE) 1 BETA SUBCOMPLEX, 4 PROTEIN MFI dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000024550.2|UniProtKB=F7F238 F7F238 LOC100030440 PTHR26453:SF601 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002143.4|UniProtKB=F6YF42 F6YF42 C3 PTHR11412:SF81 MACROGLOBULIN / COMPLEMENT COMPLEMENT C3 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488 immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;humoral immune response#GO:0006959;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;positive regulation of immune response#GO:0050778;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;complement activation#GO:0006956;activation of immune response#GO:0002253;immune response#GO:0006955;defense response to other organism#GO:0098542;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000017105.3|UniProtKB=F6UKA6 F6UKA6 PTHR24012:SF409 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 1 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143;binding#GO:0005488;single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000023246.1|UniProtKB=F6XRW0 F6XRW0 MOCS3 PTHR10953:SF254 UBIQUITIN-ACTIVATING ENZYME E1 ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877 tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;tRNA wobble position uridine thiolation#GO:0002143;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;protein modification by small protein conjugation or removal#GO:0070647;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;protein metabolic process#GO:0019538;tRNA thio-modification#GO:0034227;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000017142.3|UniProtKB=F6TM66 F6TM66 PYGO2 PTHR23194:SF7 PYGOPUS PYGOPUS HOMOLOG 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 Wnt signaling pathway#P00057>Pygo#P01464 MONDO|Ensembl=ENSMODG00000000992.3|UniProtKB=F7EA69 F7EA69 PTHR21096:SF0 PROTEIN FAM136A TIM DOUBLE TWIN CX3C MOTIF PROTEIN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000043713.1|UniProtKB=A0A5F8H8T8 A0A5F8H8T8 PTHR15312:SF1 PROTEIN TYROSINE PHOSPHATASE RECEPTOR TYPE C-ASSOCIATED PROTEIN PROTEIN TYROSINE PHOSPHATASE RECEPTOR TYPE C-ASSOCIATED PROTEIN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 MONDO|Ensembl=ENSMODG00000025100.2|UniProtKB=F6UP37 F6UP37 PTHR11717:SF34 LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000010425.4|UniProtKB=F6ZGY0 F6ZGY0 PPP1R1C PTHR15417:SF5 PROTEIN PHOSPHATASE INHIBITOR AND DOPAMINE- AND CAMP-REGULATED NEURONAL PHOSPHOPROTEIN PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1C enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857;phosphatase regulator activity#GO:0019208;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;phosphatase inhibitor#PC00183;phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000000569.3|UniProtKB=F6WI41 F6WI41 ZYG11A PTHR12904:SF20 FAMILY NOT NAMED PROTEIN ZYG-11 HOMOLOG A protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;Cul2-RING ubiquitin ligase complex#GO:0031462;catalytic complex#GO:1902494;transferase complex#GO:1990234 MONDO|Ensembl=ENSMODG00000007321.4|UniProtKB=F7EFE0 F7EFE0 LOC100026083 PTHR11956:SF5 ARGINYL-TRNA SYNTHETASE ARGININE--TRNA LIGASE, CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047 MONDO|Ensembl=ENSMODG00000010893.4|UniProtKB=F7FJ56 F7FJ56 TONSL PTHR46358:SF1 TONSOKU-LIKE PROTEIN TONSOKU-LIKE PROTEIN replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;DNA-templated DNA replication#GO:0006261;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596 MONDO|Ensembl=ENSMODG00000010716.4|UniProtKB=A0A5F8GMT5 A0A5F8GMT5 TPST2 PTHR12788:SF6 PROTEIN-TYROSINE SULFOTRANSFERASE 2 PROTEIN-TYROSINE SULFOTRANSFERASE 2 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220 MONDO|Ensembl=ENSMODG00000013827.4|UniProtKB=F6SEB4 F6SEB4 ZCCHC10 PTHR13491:SF0 ZCCHC10 PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10 MONDO|Ensembl=ENSMODG00000037695.1|UniProtKB=A0A5F8H2V6 A0A5F8H2V6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000004952.4|UniProtKB=F7A6H7 F7A6H7 VGF PTHR15159:SF2 NEUROSECRETORY PROTEIN VGF NEUROSECRETORY PROTEIN VGF signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546 synaptic signaling#GO:0099536;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of synaptic plasticity#GO:0048167;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of neuronal synaptic plasticity#GO:0048168;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000017322.2|UniProtKB=F6WWL0 F6WWL0 GUCA2A PTHR11318:SF3 GUANYLIN FAMILY MEMBER GUANYLIN cyclase regulator activity#GO:0010851;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000025630.3|UniProtKB=F6XWG5 F6XWG5 PTHR45904:SF1 TRNA (URACIL-5-)-METHYLTRANSFERASE TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG B RNA methyltransferase#PC00033 MONDO|Ensembl=ENSMODG00000020995.4|UniProtKB=F6RK10 F6RK10 RWDD2B PTHR15955:SF8 RWD DOMAIN CONTAINING PROTEIN 2 RWD DOMAIN-CONTAINING PROTEIN 2B ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000010611.4|UniProtKB=F7G818 F7G818 PTHR10962:SF5 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2C peptide binding#GO:0042277;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000013867.4|UniProtKB=F6WPA3 F6WPA3 ALS2CL PTHR46089:SF1 ALSIN HOMOLOG ALS2 C-TERMINAL-LIKE PROTEIN enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;intracellular transport#GO:0046907 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 MONDO|Ensembl=ENSMODG00000013152.4|UniProtKB=F7ABY1 F7ABY1 TOP2A PTHR10169:SF61 DNA TOPOISOMERASE/GYRASE DNA TOPOISOMERASE 2-ALPHA ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853 resolution of meiotic recombination intermediates#GO:0000712;nucleobase-containing compound metabolic process#GO:0006139;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;programmed cell death#GO:0012501;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cell death#GO:0008219;reciprocal homologous recombination#GO:0140527;reproductive process#GO:0022414;homologous recombination#GO:0035825;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;organelle organization#GO:0006996;cellular process#GO:0009987;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;meiosis I#GO:0007127;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;apoptotic process#GO:0006915;cell cycle process#GO:0022402;execution phase of apoptosis#GO:0097194;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular component disassembly#GO:0022411;chromosome condensation#GO:0030261 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 DNA replication#P00017>Top#P00530;DNA replication#P00017>DNA Topisomerase#P00536 MONDO|Ensembl=ENSMODG00000025130.3|UniProtKB=F6YS34 F6YS34 LOC100017717 PTHR10334:SF459 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLIOMA PATHOGENESIS-RELATED PROTEIN 1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000023225.1|UniProtKB=F7AVH6 F7AVH6 UCN PTHR15035:SF11 CORTICOLIBERIN/UROCORTIN UROCORTIN enzyme inhibitor activity#GO:0004857;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;neuropeptide receptor binding#GO:0071855;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;molecular function inhibitor activity#GO:0140678;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of system process#GO:0044057;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;regulation of hormone levels#GO:0010817;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of hormone secretion#GO:0046883;cell communication#GO:0007154;regulation of secretion#GO:0051046;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;positive regulation of hormone secretion#GO:0046887;positive regulation of secretion#GO:0051047 cell body#GO:0044297;cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025 peptide hormone#PC00179;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000023905.1|UniProtKB=F7CMH3 F7CMH3 PTHR11374:SF59 UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE UDP-GLUCOSE 6-DEHYDROGENASE macromolecule metabolic process#GO:0043170;glycosaminoglycan biosynthetic process#GO:0006024;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycosaminoglycan metabolic process#GO:0030203;aminoglycan biosynthetic process#GO:0006023 oxidoreductase#PC00176;dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000015507.4|UniProtKB=A0A5F8H9Z5 A0A5F8H9Z5 ARPC2 PTHR12058:SF0 ARP2/3 COMPLEX 34 KDA SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 2 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;cortical actin cytoskeleton organization#GO:0030866;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin polymerization or depolymerization#GO:0008154;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;actin cytoskeleton#GO:0015629;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 MONDO|Ensembl=ENSMODG00000018238.4|UniProtKB=F6PG63 F6PG63 ETV6 PTHR11849:SF19 ETS TRANSCRIPTION FACTOR ETV6 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000014075.3|UniProtKB=F6R532 F6R532 PTHR11119:SF22 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SOLUTE CARRIER FAMILY 23 MEMBER 4 transporter#PC00227 MONDO|Ensembl=ENSMODG00000021455.4|UniProtKB=F7FBS2 F7FBS2 ARHGAP28 PTHR14963:SF5 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 28 enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of small GTPase mediated signal transduction#GO:0051056;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of actin filament bundle assembly#GO:0032231;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;regulation of signal transduction#GO:0009966;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;regulation of cell communication#GO:0010646;negative regulation of cytoskeleton organization#GO:0051494 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000046571.1|UniProtKB=A0A5F8H034 A0A5F8H034 PTHR16675:SF67 MHC CLASS I-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000047082.1|UniProtKB=A0A5F8GYY0 A0A5F8GYY0 PTHR23411:SF39 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 1-RELATED antigen binding#GO:0003823;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 response to external stimulus#GO:0009605;defense response#GO:0006952;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;adaptive immune response#GO:0002250;response to other organism#GO:0051707;immune response#GO:0006955;complement activation#GO:0006956;response to bacterium#GO:0009617;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;antibacterial humoral response#GO:0019731;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;immune effector process#GO:0002252;defense response to other organism#GO:0098542;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000049684.1|UniProtKB=A0A5F8GU20 A0A5F8GU20 ATP6V1F PTHR13861:SF2 VACUOLAR ATP SYNTHASE SUBUNIT F V-TYPE PROTON ATPASE SUBUNIT F membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;ATP synthase#PC00002 MONDO|Ensembl=ENSMODG00000012784.4|UniProtKB=F6S0U4 F6S0U4 VPS35 PTHR11099:SF0 VACUOLAR SORTING PROTEIN 35 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 35 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;cytosolic transport#GO:0016482;endocytic recycling#GO:0032456;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;protein localization to cell periphery#GO:1990778;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;endosome to plasma membrane protein transport#GO:0099638;establishment of protein localization to membrane#GO:0090150;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;retromer complex#GO:0030904;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;protein-containing complex#GO:0032991;membrane#GO:0016020 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000016651.4|UniProtKB=A0A5F8GJC5 A0A5F8GJC5 FAM234A PTHR21419:SF7 FAMILY NOT NAMED PROTEIN FAM234A cellular anatomical structure#GO:0110165;cell surface#GO:0009986 MONDO|Ensembl=ENSMODG00000045637.1|UniProtKB=A0A5F8HHG7 A0A5F8HHG7 PTHR24100:SF155 BUTYROPHILIN CD276 ANTIGEN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cell communication#GO:0007154;regulation of immune response#GO:0050776;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000002645.4|UniProtKB=F7DIC1 F7DIC1 LOC100021416 PTHR44533:SF3 DEAD/H RNA HELICASE, PUTATIVE-RELATED ATP-DEPENDENT RNA HELICASE DDX60-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;response to stress#GO:0006950;defense response to virus#GO:0051607;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;response to virus#GO:0009615 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000014468.3|UniProtKB=F7A5E9 F7A5E9 DHX40 PTHR18934:SF234 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX40-RELATED isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000005984.4|UniProtKB=F6SLD8 F6SLD8 SLC6A1 PTHR11616:SF138 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 1 amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;transport#GO:0006810;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655 axon#GO:0030424;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000019923.4|UniProtKB=F6VNV8 F6VNV8 NUP160 PTHR21286:SF0 NUCLEAR PORE COMPLEX PROTEIN NUP160 NUCLEAR PORE COMPLEX PROTEIN NUP160 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 nuclear export#GO:0051168;nuclear transport#GO:0051169;response to nitrogen compound#GO:1901698;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;organelle localization#GO:0051640;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;nucleobase-containing compound transport#GO:0015931;cellular response to stimulus#GO:0051716;telomere localization#GO:0034397;chromosome organization#GO:0051276;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;ribosomal subunit export from nucleus#GO:0000054;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein transport#GO:0015031;protein import into nucleus#GO:0006606;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;cellular response to stress#GO:0033554;ribosome biogenesis#GO:0042254;telomere tethering at nuclear periphery#GO:0034398;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;response to stimulus#GO:0050896;ribosomal large subunit export from nucleus#GO:0000055;cellular component organization#GO:0016043;response to abiotic stimulus#GO:0009628;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;chromosome localization#GO:0050000;response to temperature stimulus#GO:0009266;protein export from nucleus#GO:0006611;gene expression#GO:0010467;response to chemical#GO:0042221;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;response to stress#GO:0006950;organelle organization#GO:0006996;response to heat#GO:0009408;cellular component biogenesis#GO:0044085;cellular response to heat#GO:0034605 organelle envelope#GO:0031967;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 MONDO|Ensembl=ENSMODG00000020960.4|UniProtKB=F6SNV5 F6SNV5 RIPK4 PTHR24198:SF65 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN RECEPTOR-INTERACTING SERINE_THREONINE-PROTEIN KINASE 4 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000046672.1|UniProtKB=A0A5F8HD98 A0A5F8HD98 DNAJC17 PTHR44313:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 17 DNAJ HOMOLOG SUBFAMILY C MEMBER 17 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex disassembly#GO:0032984;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;cellular component disassembly#GO:0022411;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000043302.1|UniProtKB=A0A5F8HGP6 A0A5F8HGP6 TADA2B PTHR12374:SF63 TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED TRANSCRIPTIONAL ADAPTER 2-BETA transcription coactivator activity#GO:0003713;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682 cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000011639.4|UniProtKB=F7FXZ4 F7FXZ4 GMFB PTHR11249:SF3 GLIAL FACTOR NATURATION FACTOR GLIA MATURATION FACTOR BETA protein-containing complex binding#GO:0044877;binding#GO:0005488 regulation of actin nucleation#GO:0051125;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;negative regulation of cytoskeleton organization#GO:0051494;actin filament-based process#GO:0030029;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000010115.4|UniProtKB=F6X3R6 F6X3R6 MARCHF10 PTHR14471:SF5 MARCH7/10 E3 UBIQUITIN PROTEIN LIGASE FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE MARCHF10-RELATED ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000011242.3|UniProtKB=F6RMT7 F6RMT7 SUFU PTHR10928:SF2 SUPPRESSOR OF FUSED SUPPRESSOR OF FUSED HOMOLOG molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311 negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 Hedgehog signaling pathway#P00025>Su(fu)#P00699 MONDO|Ensembl=ENSMODG00000004297.4|UniProtKB=F7FWG3 F7FWG3 PICALM PTHR22951:SF16 CLATHRIN ASSEMBLY PROTEIN PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;clathrin binding#GO:0030276;SNARE binding#GO:0000149;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167 receptor-mediated endocytosis#GO:0006898;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;organelle organization#GO:0006996;cellular component organization#GO:0016043 extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;clathrin-coated vesicle#GO:0030136;synaptic membrane#GO:0097060;endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;presynapse#GO:0098793;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982 vesicle coat protein#PC00235 MONDO|Ensembl=ENSMODG00000017410.4|UniProtKB=F7AJJ0 F7AJJ0 LOC100019177 PTHR11639:SF148 S100 CALCIUM-BINDING PROTEIN PROTEIN S100 protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 cellular process#GO:0009987;cell motility#GO:0048870;endothelial cell migration#GO:0043542;cell migration#GO:0016477 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 calmodulin-related#PC00061;calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000011507.4|UniProtKB=F6V0Y2 F6V0Y2 PTHR10614:SF2 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 4 receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;protein binding#GO:0005515;signaling adaptor activity#GO:0035591 cell surface receptor signaling pathway#GO:0007166;cellular response to insulin stimulus#GO:0032869;cellular process#GO:0009987;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;response to peptide hormone#GO:0043434;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;insulin-like growth factor receptor signaling pathway#GO:0048009;cellular response to endogenous stimulus#GO:0071495 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 Gonadotropin-releasing hormone receptor pathway#P06664>IRS#P06759;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899 MONDO|Ensembl=ENSMODG00000016149.4|UniProtKB=F7D6W5 F7D6W5 MAPK8IP3 PTHR13886:SF3 JNK/SAPK-ASSOCIATED PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 3 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;MAP kinase scaffold activity#GO:0005078;structural molecule activity#GO:0005198;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;protein complex scaffold activity#GO:0140378;cytoskeletal protein binding#GO:0008092 vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018424.4|UniProtKB=F6XU40 F6XU40 DCP1B PTHR16290:SF5 TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1 MRNA-DECAPPING ENZYME 1B mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;RNA decapping#GO:0110154;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468 organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;mRNA capping factor#PC00145 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 MONDO|Ensembl=ENSMODG00000012481.3|UniProtKB=F6Q400 F6Q400 SNRNP35 PTHR13952:SF31 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 35 KDA PROTEIN mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;snRNA binding#GO:0017069 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000016692.4|UniProtKB=F6WS89 F6WS89 PSMA7 PTHR11599:SF40 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-7 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 MONDO|Ensembl=ENSMODG00000047289.1|UniProtKB=F6Y4F4 F6Y4F4 PTHR46459:SF1 E1A-BINDING PROTEIN P400-RELATED E1A-BINDING PROTEIN P400 binding#GO:0005488;chromatin binding#GO:0003682 macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950 histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;ATPase complex#GO:1904949;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;acetyltransferase complex#GO:1902493;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nuclear chromosome#GO:0000228;H4 histone acetyltransferase complex#GO:1902562;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000046395.1|UniProtKB=F6TH24 F6TH24 PTHR23226:SF430 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 1010-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000013281.4|UniProtKB=F7AA71 F7AA71 APC PTHR12607:SF11 ADENOMATOUS POLYPOSIS COLI PROTEIN FAMILY ADENOMATOUS POLYPOSIS COLI PROTEIN cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of protein depolymerization#GO:1901880;cell migration#GO:0016477;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;regulation of microtubule polymerization or depolymerization#GO:0031110;regulation of protein depolymerization#GO:1901879;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;system development#GO:0048731;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;regulation of microtubule-based process#GO:0032886;negative regulation of signal transduction#GO:0009968;regulation of microtubule cytoskeleton organization#GO:0070507;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;regulation of canonical Wnt signaling pathway#GO:0060828;multicellular organism development#GO:0007275;cell fate specification#GO:0001708;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cell fate commitment#GO:0045165;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;animal gross anatomical part developmental process#GO:0160108 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoplasmic microtubule#GO:0005881;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;extrinsic component of plasma membrane#GO:0019897;polymeric cytoskeletal fiber#GO:0099513;extrinsic component of membrane#GO:0019898;intracellular protein-containing complex#GO:0140535;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232 Wnt signaling pathway#P00057>APC#P01468;Angiogenesis#P00005>APC#P00195 MONDO|Ensembl=ENSMODG00000042775.1|UniProtKB=A0A5F8GG72 A0A5F8GG72 CIDEB PTHR12306:SF10 CELL DEATH ACTIVATOR CIDE LIPID TRANSFERASE CIDEB molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;lipid transfer activity#GO:0120013 lipid storage#GO:0019915;cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219;organelle organization#GO:0006996;programmed cell death#GO:0012501;cellular component organization#GO:0016043;organelle fusion#GO:0048284;lipid droplet organization#GO:0034389;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000002783.2|UniProtKB=F6YGC2 F6YGC2 COG8 PTHR21311:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;retrograde transport, vesicle recycling within Golgi#GO:0000301;establishment of localization#GO:0051234;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;COG complex#GO:0017119;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000020945.4|UniProtKB=H9H7U4 H9H7U4 LOC100017969 PTHR26453:SF86 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038098.1|UniProtKB=H9H8D0 H9H8D0 PTHR48001:SF39 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000014493.4|UniProtKB=A0A5F8HBS9 A0A5F8HBS9 LAYN PTHR14789:SF2 CHONDROLECTIN VARIANT CHODLFDELTAE. LAYILIN ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;organic acid binding#GO:0043177 MONDO|Ensembl=ENSMODG00000006153.3|UniProtKB=F7BSM1 F7BSM1 TAMM41 PTHR13619:SF0 PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;phosphatidylglycerol biosynthetic process#GO:0006655;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phosphatidylglycerol metabolic process#GO:0046471;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000037245.1|UniProtKB=A0A5F8GQ24 A0A5F8GQ24 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000011413.4|UniProtKB=K7E4K0 K7E4K0 LCP1 PTHR19961:SF35 FIMBRIN/PLASTIN PLASTIN-2 actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;actin filament bundle assembly#GO:0051017;actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;actin filament#GO:0005884;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000008801.3|UniProtKB=A0A5F8GMH3 A0A5F8GMH3 SOS1 PTHR23113:SF168 GUANINE NUCLEOTIDE EXCHANGE FACTOR SON OF SEVENLESS HOMOLOG 1 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 CCKR signaling map#P06959>SOS1#P07061;B cell activation#P00010>SOS#P00379;Angiogenesis#P00005>SOS-1#P00193;PDGF signaling pathway#P00047>SOS#P01159;EGF receptor signaling pathway#P00018>SOS#P00558;Integrin signalling pathway#P00034>SOS#P00920;PI3 kinase pathway#P00048>SOS#P01185;FGF signaling pathway#P00021>SOS#P00641;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>SOS#P00883;T cell activation#P00053>SOS#P01307;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Sos#P00850;Gonadotropin-releasing hormone receptor pathway#P06664>Sos#P06849;Ras Pathway#P04393>SOS#P04552;Interleukin signaling pathway#P00036>SOS#P00981 MONDO|Ensembl=ENSMODG00000015524.3|UniProtKB=F6VI71 F6VI71 YPEL5 PTHR13848:SF56 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 5 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000036594.1|UniProtKB=A0A5F8G5S8 A0A5F8G5S8 SYCE3 PTHR36686:SF1 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 3 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 3 reciprocal homologous recombination#GO:0140527;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;homologous recombination#GO:0035825;reproductive process#GO:0022414;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;nucleobase-containing compound metabolic process#GO:0006139;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;homologous chromosome pairing at meiosis#GO:0007129;cellular component assembly#GO:0022607;synaptonemal complex assembly#GO:0007130;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;central element#GO:0000801;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;synaptonemal structure#GO:0099086;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793 MONDO|Ensembl=ENSMODG00000050689.1|UniProtKB=A0A5F8H5R9 A0A5F8H5R9 PTHR23304:SF183 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000041699.1|UniProtKB=A0A5F8GWR3 A0A5F8GWR3 PTHR23262:SF180 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 12-1-RELATED structural protein#PC00211 MONDO|Ensembl=ENSMODG00000005011.4|UniProtKB=A0A5F8GZL9 A0A5F8GZL9 FBN3 PTHR24039:SF0 FIBRILLIN-RELATED FIBRILLIN-3 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;glucose metabolic process#GO:0006006;glucose homeostasis#GO:0042593;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate homeostasis#GO:0033500;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975 extracellular matrix structural protein#PC00103 MONDO|Ensembl=ENSMODG00000020223.4|UniProtKB=F7FXI4 F7FXI4 MEF2C PTHR11945:SF25 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2C nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;histone deacetylase binding#GO:0042826;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;heart development#GO:0007507;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;circulatory system development#GO:0072359;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 MADS box transcription factor#PC00250 Oxidative stress response#P00046>MEF-2#P01128;p38 MAPK pathway#P05918>MEF#P06023;CCKR signaling map#P06959>MEF2C#P07222 MONDO|Ensembl=ENSMODG00000024557.2|UniProtKB=F7F1P0 F7F1P0 PTHR22705:SF0 ZINC FINGER, ZZ DOMAIN CONTAINING 3 ZZ-TYPE ZINC FINGER-CONTAINING PROTEIN 3 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000002927.4|UniProtKB=F6PMI0 F6PMI0 OTULINL PTHR33662:SF1 OTU DEUBIQUITINASE WITH LINEAR LINKAGE-SPECIFICITY A-RELATED INACTIVE UBIQUITIN THIOESTERASE OTULINL side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;cytoplasmic side of membrane#GO:0098562;endomembrane system#GO:0012505;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;cytoplasm#GO:0005737;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000018551.4|UniProtKB=F7GCS3 F7GCS3 PTHR21502:SF8 ZINC FINGER PROTEIN DZIP1 CILIUM ASSEMBLY PROTEIN DZIP1L cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000015995.5|UniProtKB=A0A5F8H4Y3 A0A5F8H4Y3 SNED1 PTHR24044:SF411 NOTCH LIGAND FAMILY MEMBER SUSHI, NIDOGEN AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 1 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000005132.4|UniProtKB=F7F5Q8 F7F5Q8 PTHR24377:SF1037 IP01015P-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000038434.1|UniProtKB=F7DBN0 F7DBN0 LOC100021480 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005765.4|UniProtKB=F6QD76 F6QD76 SLC35G1 PTHR22911:SF138 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G1 establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;export from cell#GO:0140352;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;regulation of cytosolic calcium ion concentration#GO:0051480 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transporter#PC00227 MONDO|Ensembl=ENSMODG00000011949.4|UniProtKB=F7CV27 F7CV27 CC2D1A PTHR13076:SF8 COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1A transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000012787.4|UniProtKB=F7CCN9 F7CCN9 LOC100030233 PTHR26453:SF19 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10D4-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013743.4|UniProtKB=F6X7Q0 F6X7Q0 LHFPL5 PTHR12489:SF18 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 5 PROTEIN multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;sensory perception of sound#GO:0007605;response to abiotic stimulus#GO:0009628;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to mechanical stimulus#GO:0009612;system process#GO:0003008;response to external stimulus#GO:0009605;detection of mechanical stimulus#GO:0050982;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000013365.4|UniProtKB=F7DTK7 F7DTK7 SECISBP2 PTHR13284:SF9 GH01354P SELENOCYSTEINE INSERTION SEQUENCE-BINDING PROTEIN 2 RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021;mRNA 3'-UTR binding#GO:0003730;protein-containing complex binding#GO:0044877;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 protein metabolic process#GO:0019538;translation#GO:0006412;regulation of macromolecule metabolic process#GO:0060255;protein biosynthetic process#GO:0160307;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;translational elongation#GO:0006414;metabolic process#GO:0008152;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000005197.2|UniProtKB=F7A2A2 F7A2A2 HIGD2A PTHR12297:SF18 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 2A cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000040340.1|UniProtKB=A0A5F8H0R0 A0A5F8H0R0 LOC100030366 PTHR26454:SF165 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6T1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002296.4|UniProtKB=F6YE71 F6YE71 ASB2 PTHR24173:SF33 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT AND SOCS BOX PROTEIN 2 proteasomal protein catabolic process#GO:0010498;multicellular organismal process#GO:0032501;heart development#GO:0007507;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;animal organ development#GO:0048513;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;developmental process#GO:0032502;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;circulatory system development#GO:0072359;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;system development#GO:0048731;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;animal gross anatomical part developmental process#GO:0160108 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000047954.1|UniProtKB=A0A5F8H0Y3 A0A5F8H0Y3 GGPS1 PTHR12001:SF44 GERANYLGERANYL PYROPHOSPHATE SYNTHASE GERANYLGERANYL PYROPHOSPHATE SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 isoprenoid biosynthetic process#GO:0008299;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;isoprenoid metabolic process#GO:0006720;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 metabolite interconversion enzyme#PC00262 Cholesterol biosynthesis#P00014>Dimethylallyl trans-transferase#P00490 MONDO|Ensembl=ENSMODG00000051061.1|UniProtKB=A0A5F8GXC0 A0A5F8GXC0 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010988.3|UniProtKB=H9H6G9 H9H6G9 PTHR24028:SF318 CADHERIN-87A PROTOCADHERIN BETA-16 cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000024640.1|UniProtKB=F6XCF5 F6XCF5 LOC100021904 PTHR10516:SF301 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1A-RELATED cis-trans isomerase activity#GO:0016859;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 calcium-mediated signaling#GO:0019722;macromolecule metabolic process#GO:0043170;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of system process#GO:0044057;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of calcium ion transport#GO:0051924;regulation of monoatomic ion transport#GO:0043269;macromolecule biosynthetic process#GO:0009059;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;protein metabolic process#GO:0019538;regulation of heart contraction#GO:0008016;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of transmembrane transport#GO:0034762;primary metabolic process#GO:0044238;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of release of sequestered calcium ion into cytosol#GO:0051279;metabolic process#GO:0008152;regulation of multicellular organismal process#GO:0051239;intracellular signaling cassette#GO:0141124;protein maturation#GO:0051604;gene expression#GO:0010467;signal transduction#GO:0007165;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;regulation of muscle contraction#GO:0006937;signaling#GO:0023052;protein folding#GO:0006457;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of muscle system process#GO:0090257 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;sarcoplasm#GO:0016528;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;sarcoplasmic reticulum membrane#GO:0033017;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;sarcoplasmic reticulum#GO:0016529;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 MONDO|Ensembl=ENSMODG00000018613.4|UniProtKB=F7BPR2 F7BPR2 TRIM42 PTHR25462:SF299 BONUS, ISOFORM C-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM56 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;regulation of response to cytokine stimulus#GO:0060759;positive regulation of immune system process#GO:0002684;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;regulation of cytokine-mediated signaling pathway#GO:0001959;positive regulation of response to external stimulus#GO:0032103;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;immune system process#GO:0002376;positive regulation of cytokine-mediated signaling pathway#GO:0001961;positive regulation of signaling#GO:0023056;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;defense response#GO:0006952;regulation of innate immune response#GO:0045088;innate immune response#GO:0045087;positive regulation of signal transduction#GO:0009967;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000001919.4|UniProtKB=F6W104 F6W104 FAM91A1 PTHR28441:SF7 PROTEIN FAM91A1 PROTEIN FAM91A1 macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;Golgi apparatus subcompartment#GO:0098791;vesicle#GO:0031982;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000007916.4|UniProtKB=F7GID9 F7GID9 ZNF892 PTHR24377:SF956 IP01015P-RELATED ZINC FINGER PROTEIN 892 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000049297.1|UniProtKB=A0A5F8GT15 A0A5F8GT15 KRTAP7-1 PTHR38504:SF1 KERATIN-ASSOCIATED PROTEIN 7-1 KERATIN-ASSOCIATED PROTEIN 7-1 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000002507.4|UniProtKB=F7CLC5 F7CLC5 PTHR24300:SF177 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2J2 catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;binding#GO:0005488;tetrapyrrole binding#GO:0046906 metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000008600.4|UniProtKB=F7BTX5 F7BTX5 NTPCR PTHR43146:SF1 CANCER-RELATED NUCLEOSIDE-TRIPHOSPHATASE CANCER-RELATED NUCLEOSIDE-TRIPHOSPHATASE hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000008014.4|UniProtKB=F7CL82 F7CL82 ERO1B PTHR12613:SF2 ERO1-RELATED ERO1-LIKE PROTEIN BETA catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;disulfide oxidoreductase activity#GO:0015036 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;biosynthetic process#GO:0009058;biological regulation#GO:0065007;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;protein folding#GO:0006457;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;response to unfolded protein#GO:0006986;cell communication#GO:0007154 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000006568.4|UniProtKB=F7GFH6 F7GFH6 PTHR14240:SF3 RETINITIS PIGMENTOSA GTPASE REGULATOR-INTERACTING PROTEIN X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR-INTERACTING PROTEIN 1 cilium organization#GO:0044782;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 ciliary transition zone#GO:0035869;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;9+0 non-motile cilium#GO:0097731;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000021540.4|UniProtKB=F6WUD5 F6WUD5 GIPR PTHR45620:SF5 PDF RECEPTOR-LIKE PROTEIN-RELATED GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018340.4|UniProtKB=A0A5F8HJG0 A0A5F8HJG0 TEAD4 PTHR11834:SF2 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED TRANSCRIPTIONAL ENHANCER FACTOR TEF-3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;animal gross anatomical part developmental process#GO:0160108;embryonic organ development#GO:0048568;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;hippo signaling#GO:0035329;embryo development#GO:0009790;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 MONDO|Ensembl=ENSMODG00000011120.4|UniProtKB=F7FZY6 F7FZY6 PCGF6 PTHR45893:SF2 POLYCOMB GROUP RING FINGER PROTEIN POLYCOMB GROUP RING FINGER PROTEIN 6 regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 nuclear protein-containing complex#GO:0140513;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;PcG protein complex#GO:0031519;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000007319.3|UniProtKB=F7EXU2 F7EXU2 PTHR21622:SF0 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 disulfide oxidoreductase activity#GO:0015036;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;metabolic process#GO:0008152;intracellular transport#GO:0046907;transport#GO:0006810;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;mitochondrial protein import pathway#GO:7770058;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;localization#GO:0051179;protein metabolic process#GO:0019538;cellular localization#GO:0051641;mitochondrial transport#GO:0006839;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000001913.4|UniProtKB=F6W146 F6W146 ACER1 PTHR46139:SF2 ALKALINE CERAMIDASE ALKALINE CERAMIDASE 1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 sphingoid biosynthetic process#GO:0046520;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;cellular process#GO:0009987;lipid catabolic process#GO:0016042;alcohol biosynthetic process#GO:0046165;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000016145.2|UniProtKB=F7D7D6 F7D7D6 ZNF436 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000006743.4|UniProtKB=K7E3Z4 K7E3Z4 RANBP17 PTHR12596:SF8 EXPORTIN 4,7-RELATED RAN-BINDING PROTEIN 17 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein transport#GO:0015031;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein export from nucleus#GO:0006611;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036 organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622 transporter#PC00227 MONDO|Ensembl=ENSMODG00000004676.4|UniProtKB=F6U6K9 F6U6K9 KIRREL3 PTHR11640:SF49 NEPHRIN KIN OF IRRE-LIKE PROTEIN 3 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell junction organization#GO:0034330;synapse assembly#GO:0007416;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;cell adhesion#GO:0007155 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000005512.3|UniProtKB=A0A5F8GZG3 A0A5F8GZG3 SELENOO PTHR12153:SF15 SELENOPROTEIN O PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL MONDO|Ensembl=ENSMODG00000048417.1|UniProtKB=A0A5F8H7I6 A0A5F8H7I6 CUTC PTHR12598:SF0 COPPER HOMEOSTASIS PROTEIN CUTC COPPER HOMEOSTASIS PROTEIN CUTC HOMOLOG transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000004274.4|UniProtKB=F6TER0 F6TER0 B4GALT7 PTHR19300:SF30 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 7 glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 Wnt signaling pathway#P00057>Calcineurin#P01446 MONDO|Ensembl=ENSMODG00000045185.1|UniProtKB=A0A5F8HH51 A0A5F8HH51 LOC100020324 PTHR26453:SF21 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2W6-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000013097.5|UniProtKB=A0A5F8HJZ5 A0A5F8HJZ5 RANGAP1 PTHR24113:SF12 RAN GTPASE-ACTIVATING PROTEIN 1 RAN GTPASE-ACTIVATING PROTEIN 1 enzyme binding#GO:0019899;binding#GO:0005488;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 intracellular transport#GO:0046907;transport#GO:0006810;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000005104.2|UniProtKB=A0A5F8G5A4 A0A5F8G5A4 PTHR10210:SF123 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 MONDO|Ensembl=ENSMODG00000017015.4|UniProtKB=F6QEX9 F6QEX9 MSTO1 PTHR13391:SF1 MITOCHONDRIAL DISTRIBUTION REGULATOR MISATO PROTEIN MISATO HOMOLOG 1 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 MONDO|Ensembl=ENSMODG00000009382.4|UniProtKB=A0A5F8GN16 A0A5F8GN16 RXFP2 PTHR24372:SF72 GLYCOPROTEIN HORMONE RECEPTOR RELAXIN RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000005190.4|UniProtKB=A0A5F8G6P9 A0A5F8G6P9 CLTB PTHR10639:SF28 CLATHRIN LIGHT CHAIN CLATHRIN LIGHT CHAIN B protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;plasma membrane#GO:0005886;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;coated vesicle#GO:0030135;coated membrane#GO:0048475;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;coated vesicle membrane#GO:0030662;synapse#GO:0045202;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;cell junction#GO:0030054;clathrin vesicle coat#GO:0030125;cytoplasm#GO:0005737;vesicle coat#GO:0030120;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;presynapse#GO:0098793;secretory vesicle#GO:0099503 vesicle coat protein#PC00235;membrane traffic protein#PC00150 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Huntington disease#P00029>Clathrin#P00798;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722 MONDO|Ensembl=ENSMODG00000021241.2|UniProtKB=F7DX68 F7DX68 PAQR9 PTHR20855:SF143 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR EPSILON molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000047556.1|UniProtKB=A0A5F8HDE0 A0A5F8HDE0 TMEM233 PTHR14948:SF19 NG5 TRANSMEMBRANE PROTEIN 233 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000012727.4|UniProtKB=F6THQ2 F6THQ2 ANKRD40 PTHR24192:SF3 ANKYRIN REPEAT DOMAIN 40 ANKYRIN REPEAT DOMAIN 40 MONDO|Ensembl=ENSMODG00000020621.4|UniProtKB=F6ZAS3 F6ZAS3 NFXL1 PTHR12360:SF1 NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1 NF-X1-TYPE ZINC FINGER PROTEIN NFXL1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000009116.4|UniProtKB=F7FBV0 F7FBV0 LOC100029470 PTHR22950:SF188 AMINO ACID TRANSPORTER PROTON-COUPLED AMINO ACID TRANSPORTER 1 symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;solute:proton symporter activity#GO:0015295;monoatomic cation transmembrane transporter activity#GO:0008324;neutral L-amino acid transmembrane transporter activity#GO:0015175;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;glycine transmembrane transporter activity#GO:0015187;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075 glycine transport#GO:0015816;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;monoatomic ion transport#GO:0006811;carboxylic acid transmembrane transport#GO:1905039;alanine transport#GO:0032328;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774 amino acid transporter#PC00046;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000008636.2|UniProtKB=F6PGL3 F6PGL3 GALM PTHR10091:SF0 ALDOSE-1-EPIMERASE GALACTOSE MUTAROTASE isomerase activity#GO:0016853;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;hexose metabolic process#GO:0019318;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate catabolic process#GO:0016052;glucose metabolic process#GO:0006006 epimerase/racemase#PC00096 MONDO|Ensembl=ENSMODG00000024202.2|UniProtKB=F6S4U6 F6S4U6 ARL4D PTHR11711:SF137 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4D ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 MONDO|Ensembl=ENSMODG00000049862.1|UniProtKB=A0A5F8HJA3 A0A5F8HJA3 MCIDAS PTHR13372:SF3 GEMININ MULTICILIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;cell projection assembly#GO:0030031;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of DNA-templated DNA replication initiation#GO:0030174;cellular component assembly#GO:0022607;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle assembly#GO:0070925;cilium organization#GO:0044782;regulation of DNA replication#GO:0006275;regulation of biological process#GO:0050789;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000004698.4|UniProtKB=F6TQP1 F6TQP1 LRP2BP PTHR44554:SF1 LRP2-BINDING PROTEIN LRP2-BINDING PROTEIN MONDO|Ensembl=ENSMODG00000014985.4|UniProtKB=A0A5F8GK20 A0A5F8GK20 PTHR22802:SF325 C-TYPE LECTIN SUPERFAMILY MEMBER LOW AFFINITY IMMUNOGLOBULIN EPSILON FC RECEPTOR binding#GO:0005488;signaling receptor activity#GO:0038023;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000019365.4|UniProtKB=A0A5F8HB00 A0A5F8HB00 ZNF592 PTHR47222:SF1 ZINC FINGER PROTEIN 532-RELATED ZINC FINGER PROTEIN 592 MONDO|Ensembl=ENSMODG00000009210.5|UniProtKB=A0A5F8H9R0 A0A5F8H9R0 NEBL PTHR11039:SF48 NEBULIN NEBULETTE cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;system development#GO:0048731;muscle tissue development#GO:0060537;supramolecular fiber organization#GO:0097435;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;developmental process#GO:0032502;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869;actin filament organization#GO:0007015;tissue development#GO:0009888;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;circulatory system development#GO:0072359;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cellular anatomical entity morphogenesis#GO:0032989;striated muscle tissue development#GO:0014706;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;heart development#GO:0007507;cellular component assembly#GO:0022607;cardiac muscle cell differentiation#GO:0055007;cytoskeleton organization#GO:0007010 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;sarcomere#GO:0030017;membraneless organelle#GO:0043228;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;I band#GO:0031674 MONDO|Ensembl=ENSMODG00000017172.3|UniProtKB=F6QD38 F6QD38 ZMYND19 PTHR46831:SF1 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 19 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 19 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000021248.4|UniProtKB=F6TJB1 F6TJB1 LOC100018556 PTHR23248:SF38 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;cellular component organization#GO:0016043;localization#GO:0051179;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;lipid transport#GO:0006869;endomembrane system organization#GO:0010256;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;phospholipid transport#GO:0015914;membrane organization#GO:0061024;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 MONDO|Ensembl=ENSMODG00000037575.1|UniProtKB=A0A5F8G6A9 A0A5F8G6A9 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000023323.3|UniProtKB=F7F245 F7F245 CABP7 PTHR46311:SF1 CALCIUM-BINDING PROTEIN 8-RELATED CALCIUM-BINDING PROTEIN 7 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802 MONDO|Ensembl=ENSMODG00000013309.4|UniProtKB=F6YVN0 F6YVN0 SV2B PTHR23511:SF2 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2B regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;modulation of chemical synaptic transmission#GO:0050804;regulation of synaptic vesicle exocytosis#GO:2000300;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of neurotransmitter secretion#GO:0046928;regulation of signaling#GO:0023051;inorganic ion homeostasis#GO:0098771;regulation of neurotransmitter transport#GO:0051588;calcium ion homeostasis#GO:0055074;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of secretion#GO:0051046;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;regulation of localization#GO:0032879;intracellular chemical homeostasis#GO:0055082;regulation of transport#GO:0051049;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725 synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;presynapse#GO:0098793;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054 MONDO|Ensembl=ENSMODG00000049632.1|UniProtKB=F7G1Y8 F7G1Y8 LOC100015860 PTHR11818:SF101 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN B structural molecule activity#GO:0005198 sensory system development#GO:0048880;multicellular organismal process#GO:0032501;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;sensory organ development#GO:0007423;system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000044966.1|UniProtKB=A0A5F8G837 A0A5F8G837 PTHR24377:SF641 IP01015P-RELATED ZINC FINGER PROTEIN 354B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000046949.1|UniProtKB=A0A5F8G4Y2 A0A5F8G4Y2 LOC100618165 PTHR23226:SF317 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000040488.1|UniProtKB=F6TL32 F6TL32 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000044228.1|UniProtKB=A0A5F8H4K3 A0A5F8H4K3 PTHR26453:SF627 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010630.3|UniProtKB=A0A5F8GPX7 A0A5F8GPX7 PTHR23232:SF163 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000043338.1|UniProtKB=A0A5F8GLH0 A0A5F8GLH0 LOC100022791 PTHR26450:SF395 OLFACTORY RECEPTOR 56B1-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038258.1|UniProtKB=A0A5F8HJ01 A0A5F8HJ01 YAF2 PTHR12920:SF2 RYBP AND YAF2-RELATED YY1-ASSOCIATED FACTOR 2 DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;nucleic acid binding#GO:0003676;binding#GO:0005488 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000051221.1|UniProtKB=A0A5F8G5B4 A0A5F8G5B4 PTHR11434:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT ND4L NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4L transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000042537.1|UniProtKB=A0A5F8GQG2 A0A5F8GQG2 PTHR23411:SF39 TAPASIN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 1-RELATED signaling receptor binding#GO:0005102;binding#GO:0005488;antigen binding#GO:0003823;protein binding#GO:0005515 immune system process#GO:0002376;defense response to bacterium#GO:0042742;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;immune effector process#GO:0002252;antibacterial humoral response#GO:0019731;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;defense response to other organism#GO:0098542;response to bacterium#GO:0009617;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;defense response#GO:0006952;response to external stimulus#GO:0009605;complement activation#GO:0006956;immune response#GO:0006955;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to other organism#GO:0051707;biological regulation#GO:0065007 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000001607.3|UniProtKB=F7BAK0 F7BAK0 SOSTDC1 PTHR14903:SF5 SCLEROSTIN-RELATED SCLEROSTIN DOMAIN-CONTAINING PROTEIN 1 cytokine binding#GO:0019955;protein binding#GO:0005515;binding#GO:0005488 negative regulation of BMP signaling pathway#GO:0030514;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of BMP signaling pathway#GO:0030510;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000041900.1|UniProtKB=A0A5F8GUZ5 A0A5F8GUZ5 LOC103103199 PTHR14096:SF27 APOLIPOPROTEIN L APOLIPOPROTEIN L2 binding#GO:0005488;lipid binding#GO:0008289 cellular anatomical structure#GO:0110165;membrane#GO:0016020 apolipoprotein#PC00052;transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000018130.4|UniProtKB=A0A5F8H165 A0A5F8H165 GTPBP8 PTHR46498:SF1 GTP-BINDING PROTEIN 8 GTP-BINDING PROTEIN 8 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000046154.1|UniProtKB=A0A5F8GT29 A0A5F8GT29 PTHR12084:SF0 NUCLEAR PORE GLYCOPROTEIN P62-RELATED NUCLEAR PORE GLYCOPROTEIN P62 structural molecule activity#GO:0005198;lipid binding#GO:0008289;structural constituent of nuclear pore#GO:0017056;phospholipid binding#GO:0005543;binding#GO:0005488 nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear export#GO:0051168;nuclear transport#GO:0051169;RNA localization#GO:0006403;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle envelope#GO:0031967 transporter#PC00227 MONDO|Ensembl=ENSMODG00000050806.1|UniProtKB=A0A5F8GUK0 A0A5F8GUK0 TSFM PTHR11741:SF0 ELONGATION FACTOR TS ELONGATION FACTOR TS, MITOCHONDRIAL translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;mitochondrial translation#GO:0032543;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 translation elongation factor#PC00222 MONDO|Ensembl=ENSMODG00000000769.4|UniProtKB=F6SST1 F6SST1 NCF4 PTHR15706:SF20 SH3 MULTIPLE DOMAIN NEUTROPHIL CYTOSOL FACTOR 4 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;superoxide metabolic process#GO:0006801 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000014598.4|UniProtKB=F7A3Y6 F7A3Y6 GDPD1 PTHR42758:SF1 PHOSPHATIDYLGLYCEROL PHOSPHOLIPASE C LYSOPHOSPHOLIPASE D GDPD1 carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081 lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;glycerophospholipid catabolic process#GO:0046475;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;small molecule metabolic process#GO:0044281;glycerolipid catabolic process#GO:0046503;organophosphate catabolic process#GO:0046434 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 lipase#PC00143;phospholipase#PC00186;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000003380.4|UniProtKB=A0A5F8G9Z6 A0A5F8G9Z6 SPRED2 PTHR11202:SF11 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 negative regulation of response to stimulus#GO:0048585;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000000391.4|UniProtKB=F6R7X3 F6R7X3 SMARCA5 PTHR10799:SF997 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5 binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097 negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;heterochromatin formation#GO:0031507;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA helicase#PC00011;DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 MONDO|Ensembl=ENSMODG00000003822.3|UniProtKB=F6YVC1 F6YVC1 AP1G2 PTHR22780:SF28 ADAPTIN, ALPHA/GAMMA/EPSILON AP-1 COMPLEX SUBUNIT GAMMA-LIKE 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;Golgi to endosome transport#GO:0006895;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892 Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular vesicle#GO:0097708;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;AP-1 adaptor complex#GO:0030121;trans-Golgi network transport vesicle#GO:0030140;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;Golgi apparatus#GO:0005794;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi-associated vesicle#GO:0005798 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000002578.2|UniProtKB=F7G581 F7G581 PTHR26453:SF198 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2K2 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000044145.1|UniProtKB=A0A5F8GAP4 A0A5F8GAP4 PTHR35679:SF1 RIKEN CDNA 4933402J07 GENE RIKEN CDNA 4933402J07 GENE MONDO|Ensembl=ENSMODG00000014893.3|UniProtKB=F7GGA6 F7GGA6 LACC1 PTHR30616:SF5 UNCHARACTERIZED PROTEIN YFIH PURINE NUCLEOSIDE PHOSPHORYLASE LACC1 transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;adenosine deaminase activity#GO:0004000;hydrolase activity#GO:0016787 regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;cell communication#GO:0007154;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;regulation of response to external stimulus#GO:0032101;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microbody#GO:0042579;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000003918.4|UniProtKB=A0A5F8GHI5 A0A5F8GHI5 FLT4 PTHR24416:SF49 TYROSINE-PROTEIN KINASE RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3 catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 developmental process#GO:0032502;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;positive regulation of locomotion#GO:0040017;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;tube development#GO:0035295;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;positive regulation of signal transduction#GO:0009967;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;regulation of cellular process#GO:0050794;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;sprouting angiogenesis#GO:0002040;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;angiogenesis#GO:0001525;positive regulation of signaling#GO:0023056;positive regulation of cell population proliferation#GO:0008284;vascular endothelial growth factor receptor signaling pathway#GO:0048010;positive regulation of cell motility#GO:2000147;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 Angiogenesis#P00005>VEGFR-2#P00222;VEGF signaling pathway#P00056>VEGFR-2#P01403 MONDO|Ensembl=ENSMODG00000007620.4|UniProtKB=F7C554 F7C554 CARNS1 PTHR48066:SF1 CARNOSINE SYNTHASE 1 CARNOSINE SYNTHASE 1 ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ligase activity#GO:0016874;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;ligase activity, forming carbon-nitrogen bonds#GO:0016879;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 MONDO|Ensembl=ENSMODG00000009521.2|UniProtKB=F7EV12 F7EV12 PTHR11902:SF58 ENOLASE ALPHA-ENOLASE catalytic activity#GO:0003824;phosphopyruvate hydratase activity#GO:0004634;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nicotinamide nucleotide metabolic process#GO:0046496;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056 cytosol#GO:0005829;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;lyase#PC00144 Glycolysis#P00024>Enolase#P00678 MONDO|Ensembl=ENSMODG00000001897.5|UniProtKB=F7CFQ9 F7CFQ9 FER1L6 PTHR12546:SF37 FER-1-LIKE FER-1-LIKE PROTEIN 6 cellular process#GO:0009987;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000016225.4|UniProtKB=F7FLT2 F7FLT2 PTHR46061:SF1 THYROTROPIN-RELEASING HORMONE RECEPTOR THYROTROPIN-RELEASING HORMONE RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH Receptor#P04580 MONDO|Ensembl=ENSMODG00000016709.4|UniProtKB=F7D1T6 F7D1T6 OSBPL2 PTHR10972:SF153 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 2 cholesterol binding#GO:0015485;lipid binding#GO:0008289;steroid binding#GO:0005496;alcohol binding#GO:0043178;sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;membrane#GO:0016020 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000045693.1|UniProtKB=F6ZWR2 F6ZWR2 PTHR48002:SF74 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000027827.2|UniProtKB=K7E049 K7E049 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000008652.4|UniProtKB=F6PGA8 F6PGA8 TLK1 PTHR22974:SF22 MIXED LINEAGE PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE TOUSLED-LIKE 1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cellular process#GO:0009987;cell cycle process#GO:0022402;chromosome segregation#GO:0007059;cell cycle#GO:0007049 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000049303.1|UniProtKB=H9H8I5 H9H8I5 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005320.4|UniProtKB=F7G8E6 F7G8E6 ALAS2 PTHR13693:SF58 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 5-AMINOLEVULINATE SYNTHASE, ERYTHROID-SPECIFIC, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;porphyrin-containing compound biosynthetic process#GO:0006779;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;heme biosynthetic process#GO:0006783;primary metabolic process#GO:0044238;pigment metabolic process#GO:0042440;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transaminase#PC00216 MONDO|Ensembl=ENSMODG00000000810.4|UniProtKB=F6S9S0 F6S9S0 PTHR23268:SF121 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 28 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000012985.4|UniProtKB=F7CS72 F7CS72 SLC2A6 PTHR48021:SF59 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 6 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000037981.1|UniProtKB=A0A5F8GGA8 A0A5F8GGA8 LOC100618325 PTHR26450:SF43 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000044511.1|UniProtKB=A0A5F8H6D8 A0A5F8H6D8 LOC100017088 PTHR23023:SF70 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000039440.1|UniProtKB=A0A5F8G480 A0A5F8G480 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000018796.5|UniProtKB=F7C3T6 F7C3T6 PTHR16776:SF3 EXTRACELLULAR MATRIX PROTEIN 1 EXTRACELLULAR MATRIX PROTEIN 1 regulation of multicellular organismal process#GO:0051239;regulation of bone mineralization#GO:0030500;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789 MONDO|Ensembl=ENSMODG00000013278.3|UniProtKB=A0A5F8HH79 A0A5F8HH79 SRP19 PTHR17453:SF0 SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein targeting#GO:0006605;protein targeting to membrane#GO:0006612;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;protein targeting to ER#GO:0045047;protein-containing complex organization#GO:0043933;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component assembly#GO:0022607;establishment of protein localization to endoplasmic reticulum#GO:0072599 ribonucleoprotein complex#GO:1990904;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000020208.4|UniProtKB=K7E0X3 K7E0X3 LOC103094062 PTHR23320:SF74 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 3 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 MONDO|Ensembl=ENSMODG00000020900.4|UniProtKB=H9H7R3 H9H7R3 EME1 PTHR21077:SF7 EME1 PROTEIN STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT EME1 meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;DNA replication#GO:0006260;reciprocal homologous recombination#GO:0140527;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;homologous recombination#GO:0035825;reproductive process#GO:0022414;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;DNA integrity checkpoint signaling#GO:0031570;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;resolution of meiotic recombination intermediates#GO:0000712;DNA damage checkpoint signaling#GO:0000077;replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;DNA-templated DNA replication#GO:0006261;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564 catalytic complex#GO:1902494;endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000019889.2|UniProtKB=A0A5F8GY79 A0A5F8GY79 CHRM4 PTHR24248:SF142 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M4 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>mAChR2/4#P01077;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 MONDO|Ensembl=ENSMODG00000037154.1|UniProtKB=A0A5F8G748 A0A5F8G748 PTHR23232:SF179 KRAB DOMAIN C2H2 ZINC FINGER ZINC FINGER PROTEIN 8-LIKE transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000042170.1|UniProtKB=M9MMI1 M9MMI1 PTHR44427:SF13 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 4-RELATED cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000048984.1|UniProtKB=A0A5F8GIK8 A0A5F8GIK8 GNGT2 PTHR13809:SF28 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-T2 ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cytoplasmic side of membrane#GO:0098562;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Enkephalin release#P05913>G-Protein (s)#P05977;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (i)#P05974;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;PI3 kinase pathway#P00048>Gbetagamma#P01188;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;GABA-B receptor II signaling#P05731>Ggamma#P05754;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488 MONDO|Ensembl=ENSMODG00000016234.4|UniProtKB=F7AY22 F7AY22 CD28 PTHR11494:SF7 CYTOTOXIC T-LYMPHOCYTE PROTEIN T-CELL-SPECIFIC SURFACE GLYCOPROTEIN CD28 positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;lymphocyte activation#GO:0046649;positive regulation of T cell activation#GO:0050870;antigen receptor-mediated signaling pathway#GO:0050851;regulation of T cell activation#GO:0050863;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;positive regulation of leukocyte activation#GO:0002696;regulation of leukocyte proliferation#GO:0070663;immune response-activating signaling pathway#GO:0002757;positive regulation of mononuclear cell proliferation#GO:0032946;positive regulation of cell population proliferation#GO:0008284;regulation of leukocyte activation#GO:0002694;T cell activation#GO:0042110;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of T cell proliferation#GO:0042102;regulation of lymphocyte activation#GO:0051249;immune system process#GO:0002376;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of cell activation#GO:0050867;T cell receptor signaling pathway#GO:0050852;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of leukocyte proliferation#GO:0070665;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;leukocyte activation#GO:0045321;positive regulation of cell adhesion#GO:0045785;cellular response to stimulus#GO:0051716;regulation of T cell proliferation#GO:0042129;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;positive regulation of lymphocyte proliferation#GO:0050671;cell activation#GO:0001775;regulation of cell population proliferation#GO:0042127;positive regulation of lymphocyte activation#GO:0051251;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>CD28#P01313 MONDO|Ensembl=ENSMODG00000006325.4|UniProtKB=F7AFM6 F7AFM6 WDR37 PTHR19855:SF12 WD40 REPEAT PROTEIN 12, 37 WD REPEAT-CONTAINING PROTEIN 37 MONDO|Ensembl=ENSMODG00000044921.1|UniProtKB=A0A5F8HI50 A0A5F8HI50 PTHR24379:SF131 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 712 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000017369.4|UniProtKB=F6VYX5 F6VYX5 LCN15 PTHR11430:SF64 LIPOCALIN LIPOCALIN-15 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000023283.2|UniProtKB=A0A5F8H2K2 A0A5F8H2K2 RNF224 PTHR47454:SF1 RING FINGER PROTEIN 224 RING FINGER PROTEIN 224 MONDO|Ensembl=ENSMODG00000017890.4|UniProtKB=A0A5F8GU17 A0A5F8GU17 PLCZ1 PTHR10336:SF29 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE ZETA-1 phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;lipase activity#GO:0016298 regulation of biological quality#GO:0065008;positive regulation of cytosolic calcium ion concentration#GO:0007204;sexual reproduction#GO:0019953;cell activation#GO:0001775;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;reproductive process#GO:0022414;fertilization#GO:0009566;single fertilization#GO:0007338;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020 hydrolase#PC00121;lipase#PC00143;phospholipase#PC00186;metabolite interconversion enzyme#PC00262 5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 MONDO|Ensembl=ENSMODG00000014393.3|UniProtKB=F6T6Q6 F6T6Q6 NKAPD1 PTHR46940:SF1 NKAP DOMAIN-CONTAINING 1 NKAP DOMAIN CONTAINING 1 MONDO|Ensembl=ENSMODG00000020821.4|UniProtKB=F6RM57 F6RM57 IGLON5 PTHR42757:SF12 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED IGLON FAMILY MEMBER 5 heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;regulation of biological process#GO:0050789;cell-cell adhesion#GO:0098609;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of synapse assembly#GO:0051963;regulation of cellular component organization#GO:0051128;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;cell adhesion#GO:0007155;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000018299.4|UniProtKB=F6PW17 F6PW17 FERRY3 PTHR16525:SF0 PROTEIN C12ORF4 FERRY ENDOSOMAL RAB5 EFFECTOR COMPLEX SUBUNIT 3 regulation of immune effector process#GO:0002697;regulation of secretion#GO:0051046;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000005129.3|UniProtKB=F7EQN3 F7EQN3 TADA3 PTHR13556:SF2 TRANSCRIPTIONAL ADAPTER 3-RELATED TRANSCRIPTIONAL ADAPTER 3 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;SAGA-type complex#GO:0070461;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;SAGA complex#GO:0000124;chromatin#GO:0000785;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000045080.1|UniProtKB=A0A5F8G6H0 A0A5F8G6H0 SLC25A43 PTHR24089:SF246 SOLUTE CARRIER FAMILY 25 SOLUTE CARRIER FAMILY 25 MEMBER 43 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000043697.1|UniProtKB=A0A5F8GMP3 A0A5F8GMP3 PTHR24070:SF396 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN R-RAS2 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;establishment or maintenance of cell polarity#GO:0007163;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 EGF receptor signaling pathway#P00018>Ras#P00552;TGF-beta signaling pathway#P00052>Ras-GDP#P01291;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;TGF-beta signaling pathway#P00052>Ras-GTP#P01280 MONDO|Ensembl=ENSMODG00000010198.4|UniProtKB=F6ST88 F6ST88 ZDHHC6 PTHR22883:SF23 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC6 catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting#GO:0006605;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000019397.3|UniProtKB=F6WC71 F6WC71 PTHR24103:SF676 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000018113.3|UniProtKB=F7FF99 F7FF99 MLF2 PTHR13105:SF4 MYELOID LEUKEMIA FACTOR MYELOID LEUKEMIA FACTOR 2 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000038939.1|UniProtKB=F6V1D4 F6V1D4 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000016812.5|UniProtKB=F7FV88 F7FV88 LATS1 PTHR24356:SF138 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE LATS1 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of biological process#GO:0050789;regulation of growth#GO:0040008;cellular response to stimulus#GO:0051716;cell cycle process#GO:0022402;cell cycle#GO:0007049;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;regulation of developmental process#GO:0050793;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;positive regulation of programmed cell death#GO:0043068;mitotic cell cycle phase transition#GO:0044772;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;cell cycle G1/S phase transition#GO:0044843;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;hippo signaling#GO:0035329;regulation of apoptotic process#GO:0042981;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047;positive regulation of apoptotic process#GO:0043065 spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000027927.1|UniProtKB=K7DZQ5 K7DZQ5 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000003920.4|UniProtKB=A0A5F8H9H2 A0A5F8H9H2 ATRX PTHR46357:SF1 TRANSCRIPTIONAL REGULATOR ATRX CHROMATIN REMODELER ATRX DNA binding#GO:0003677;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676 chromatin remodeling#GO:0006338;replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;cellular process#GO:0009987;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000043597.1|UniProtKB=A0A5F8GYN4 A0A5F8GYN4 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010967.4|UniProtKB=F7BC17 F7BC17 RPSA PTHR11489:SF9 40S RIBOSOMAL PROTEIN SA SMALL RIBOSOMAL SUBUNIT PROTEIN US2 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;ribosomal small subunit assembly#GO:0000028;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;translation#GO:0006412;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000014697.4|UniProtKB=A0A5F8HDQ1 A0A5F8HDQ1 MTMR4 PTHR10807:SF64 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR4 protein binding#GO:0005515;hydrolase activity#GO:0016787;binding#GO:0005488;phosphatase binding#GO:0019902;enzyme binding#GO:0019899;phosphoric ester hydrolase activity#GO:0042578;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;protein phosphatase binding#GO:0019903;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;lipid modification#GO:0030258;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020 phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000011853.4|UniProtKB=F7GDF6 F7GDF6 PTHR15012:SF33 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;cortical cytoskeleton#GO:0030863;organelle#GO:0043226;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;apical junction complex#GO:0043296;cytoskeleton#GO:0005856;adherens junction#GO:0005912;cell junction#GO:0030054;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;plasma membrane region#GO:0098590 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000009641.4|UniProtKB=F6RRH5 F6RRH5 PTHR33560:SF1 PROTEIN FAM227B PROTEIN FAM227A MONDO|Ensembl=ENSMODG00000009325.3|UniProtKB=F7GJN1 F7GJN1 PTHR12644:SF1 ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 5 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;cell migration#GO:0016477;actin nucleation#GO:0045010 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944 actin or actin-binding cytoskeletal protein#PC00041 Huntington disease#P00029>Arp2/3 complex#P00811;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 MONDO|Ensembl=ENSMODG00000001468.4|UniProtKB=F7APA5 F7APA5 TBC1D10B PTHR22957:SF207 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 10B enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 MONDO|Ensembl=ENSMODG00000004920.4|UniProtKB=F7BH06 F7BH06 PCGF1 PTHR10825:SF29 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP RING FINGER PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000021323.4|UniProtKB=F7FT00 F7FT00 FNDC3B PTHR24099:SF19 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 3B ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000006410.3|UniProtKB=F7FD96 F7FD96 TSG101 PTHR23306:SF17 TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED TUMOR SUSCEPTIBILITY GENE 101 PROTEIN protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 membrane#GO:0016020;ESCRT I complex#GO:0000813;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000023729.2|UniProtKB=F6TWQ4 F6TWQ4 PTHR16277:SF12 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 SERTA DOMAIN-CONTAINING PROTEIN 1 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000043579.1|UniProtKB=A0A5F8HAZ6 A0A5F8HAZ6 PTHR43340:SF6 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;magnesium ion binding#GO:0000287;cation binding#GO:0043169;metal ion binding#GO:0046872 nucleoside phosphate biosynthetic process#GO:1901293;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;IMP metabolic process#GO:0046040;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247;Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804;Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245 MONDO|Ensembl=ENSMODG00000004678.4|UniProtKB=F6U6J1 F6U6J1 SEMA4F PTHR11036:SF72 SEMAPHORIN SEMAPHORIN-4F protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon guidance#GO:0007411;axon development#GO:0061564;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;regulation of cellular process#GO:0050794;chemotaxis#GO:0006935;system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;taxis#GO:0042330;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000047432.1|UniProtKB=A0A5F8HAN4 A0A5F8HAN4 PTHR26450:SF43 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019137.4|UniProtKB=A0A5F8GZH9 A0A5F8GZH9 NLE1 PTHR19848:SF10 WD40 REPEAT PROTEIN NOTCHLESS PROTEIN HOMOLOG 1 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 MONDO|Ensembl=ENSMODG00000009575.4|UniProtKB=F7AX29 F7AX29 PTHR46389:SF4 POLYCOMB GROUP PROTEIN PC CHROMOBOX PROTEIN HOMOLOG 6 chromatin binding#GO:0003682;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;chromatin#GO:0000785;PcG protein complex#GO:0031519;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000010572.3|UniProtKB=F6YQP7 F6YQP7 CWF19L1 PTHR12072:SF4 CWF19, CELL CYCLE CONTROL PROTEIN CWF19-LIKE PROTEIN 1 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000040744.1|UniProtKB=A0A5F8G3G0 A0A5F8G3G0 PTHR33505:SF4 ZGC:162634 PROTEIN PREY, MITOCHONDRIAL MONDO|Ensembl=ENSMODG00000023131.2|UniProtKB=A0A5F8GPQ6 A0A5F8GPQ6 COL26A1 PTHR15427:SF19 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COLLAGEN ALPHA-1(XXVI) CHAIN biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000021452.4|UniProtKB=F7GLR2 F7GLR2 RAB12 PTHR47980:SF35 LD44762P RAS-RELATED PROTEIN RAB-12 localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;secretion#GO:0046903;secretion by cell#GO:0032940;endocytic recycling#GO:0032456;export from cell#GO:0140352;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;endosomal transport#GO:0016197;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;trans-Golgi network transport vesicle#GO:0030140;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410 MONDO|Ensembl=ENSMODG00000041490.1|UniProtKB=A0A5F8H2B1 A0A5F8H2B1 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000011665.2|UniProtKB=A0A5F8GTX0 A0A5F8GTX0 TLR9 PTHR47410:SF3 TOLL-LIKE RECEPTOR 7-RELATED TOLL-LIKE RECEPTOR 9 molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023 regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;response to virus#GO:0009615;intracellular signal transduction#GO:0035556;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;regulation of gene expression#GO:0010468;activation of innate immune response#GO:0002218;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;canonical NF-kappaB signal transduction#GO:0007249;biological regulation#GO:0065007;response to other organism#GO:0051707;immune system process#GO:0002376;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;defense response to virus#GO:0051607;toll-like receptor signaling pathway#GO:0002224;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;regulation of multicellular organismal process#GO:0051239;intracellular signaling cassette#GO:0141124 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR#P01346 MONDO|Ensembl=ENSMODG00000041565.1|UniProtKB=F7GFJ8 F7GFJ8 LOC100025235 PTHR23087:SF13 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-17 binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000019473.4|UniProtKB=F6RBB9 F6RBB9 ESM1 PTHR15428:SF0 ENDOTHELIAL CELL-SPECIFIC MOLECULE 1 ESM-1 ENDOTHELIAL CELL-SPECIFIC MOLECULE 1 protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;circulatory system development#GO:0072359;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;positive regulation of signal transduction#GO:0009967;blood vessel morphogenesis#GO:0048514;system development#GO:0048731;positive regulation of signaling#GO:0023056;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;regulation of signaling#GO:0023051;sprouting angiogenesis#GO:0002040;animal gross anatomical part developmental process#GO:0160108;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;tube development#GO:0035295;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583 MONDO|Ensembl=ENSMODG00000002524.5|UniProtKB=F7B8S9 F7B8S9 PKN1 PTHR24356:SF246 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE N1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074 MONDO|Ensembl=ENSMODG00000018945.4|UniProtKB=A0A5F8G3R9 A0A5F8G3R9 MRPL14 PTHR21037:SF3 39S RIBOSOMAL PROTEIN L14, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL14M intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000048807.1|UniProtKB=A0A5F8GH57 A0A5F8GH57 LOC100019462 PTHR20931:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 30 TETRATRICOPEPTIDE REPEAT PROTEIN 30 protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component organization#GO:0016043;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017 microtubule#GO:0005874;axoneme#GO:0005930;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasmic microtubule#GO:0005881;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;intraciliary transport particle B#GO:0030992;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 MONDO|Ensembl=ENSMODG00000045965.1|UniProtKB=A0A5F8GDX5 A0A5F8GDX5 SPTSSA PTHR47084:SF1 SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT A SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT A acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;ceramide metabolic process#GO:0006672 protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000000572.4|UniProtKB=F6X461 F6X461 CBX3 PTHR22812:SF162 CHROMOBOX PROTEIN CHROMOBOX 3 chromatin binding#GO:0003682;binding#GO:0005488 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775 MONDO|Ensembl=ENSMODG00000014246.4|UniProtKB=F6Y1P6 F6Y1P6 DHDDS PTHR10291:SF51 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 primary metabolic process#GO:0044238;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;isoprenoid biosynthetic process#GO:0008299;isoprenoid metabolic process#GO:0006720 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000018931.3|UniProtKB=F7GJQ9 F7GJQ9 PTHR10177:SF444 CYCLINS CYCLIN-A2 kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;transferase complex#GO:1990234;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin A#P04666 MONDO|Ensembl=ENSMODG00000027516.2|UniProtKB=K7E1S4 K7E1S4 PTHR12015:SF92 SMALL INDUCIBLE CYTOKINE A FRACTALKINE chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009 regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to external biotic stimulus#GO:0043207;cellular response to chemokine#GO:1990869;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326;cytokine-mediated signaling pathway#GO:0019221;chemotaxis#GO:0006935;inflammatory response#GO:0006954;cell migration#GO:0016477;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;response to other organism#GO:0051707;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;myeloid leukocyte migration#GO:0097529;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to peptide#GO:1901652;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;taxis#GO:0042330;response to cytokine#GO:0034097;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 MONDO|Ensembl=ENSMODG00000014356.4|UniProtKB=F6ZKL6 F6ZKL6 PTHR24377:SF975 IP01015P-RELATED ZINC FINGER PROTEIN 883-LIKE transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000000052.4|UniProtKB=A0A5F8GN46 A0A5F8GN46 MGA PTHR11267:SF32 T-BOX PROTEIN-RELATED MAX GENE-ASSOCIATED PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;cell fate specification#GO:0001708;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165 methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 MONDO|Ensembl=ENSMODG00000006728.3|UniProtKB=F7CX61 F7CX61 PTHR10125:SF12 P2X PURINOCEPTOR P2X PURINOCEPTOR 5 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;cellular process#GO:0009987;calcium ion transmembrane transport#GO:0070588 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000003139.3|UniProtKB=H9H621 H9H621 LOC107651113 PTHR26453:SF81 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011415.3|UniProtKB=F6RL39 F6RL39 PTHR33865:SF3 PROTEIN FAM183B CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 144 cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;ciliary base#GO:0097546 MONDO|Ensembl=ENSMODG00000011145.4|UniProtKB=F6ULF0 F6ULF0 ITIH3 PTHR10338:SF115 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H3 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000003575.4|UniProtKB=F6RYV4 F6RYV4 RND3 PTHR24072:SF24 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOE GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970 cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein#PC00020;small GTPase#PC00208 Integrin signalling pathway#P00034>Rho#P00948 MONDO|Ensembl=ENSMODG00000017882.3|UniProtKB=F6YHG6 F6YHG6 HAUS2 PTHR16039:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 2 cellular process#GO:0009987;spindle assembly#GO:0051225;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;microtubule organizing center organization#GO:0031023;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226 intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoskeleton#GO:0005856;mitotic spindle#GO:0072686;organelle#GO:0043226;cellular anatomical structure#GO:0110165;HAUS complex#GO:0070652;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;spindle microtubule#GO:0005876;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000011996.4|UniProtKB=A0A5F8HFG6 A0A5F8HFG6 TGFBR3 PTHR14002:SF7 ENDOGLIN/TGF-BETA RECEPTOR TYPE III TRANSFORMING GROWTH FACTOR BETA RECEPTOR TYPE 3 signaling receptor activity#GO:0038023;carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;transforming growth factor beta receptor activity#GO:0005024;kinase activity#GO:0016301;protein binding#GO:0005515;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;cytokine receptor binding#GO:0005126;transmembrane signaling receptor activity#GO:0004888;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;cytokine binding#GO:0019955;transforming growth factor beta binding#GO:0050431;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;response to transforming growth factor beta#GO:0071559;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;cellular developmental process#GO:0048869;mesenchyme development#GO:0060485;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;animal organ development#GO:0048513;mesenchymal cell differentiation#GO:0048762;cell surface receptor signaling pathway#GO:0007166;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;signal transduction#GO:0007165 transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>TBRIII#P06806 MONDO|Ensembl=ENSMODG00000009247.4|UniProtKB=F6RV62 F6RV62 H6PD PTHR23429:SF7 GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD GDH_6PGL ENDOPLASMIC BIFUNCTIONAL PROTEIN glucose-6-phosphate dehydrogenase activity#GO:0004345;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;pentose-phosphate shunt#GO:0006098;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glucose metabolic process#GO:0006006;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;generation of precursor metabolites and energy#GO:0006091;pentose-phosphate shunt, oxidative branch#GO:0009051 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 dehydrogenase#PC00092 MONDO|Ensembl=ENSMODG00000019260.3|UniProtKB=F6Q8P2 F6Q8P2 UNC5C PTHR12582:SF7 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5C signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;anatomical structure development#GO:0048856;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 MONDO|Ensembl=ENSMODG00000010233.4|UniProtKB=F6WLM8 F6WLM8 PTHR18034:SF3 CELL CYCLE CONTROL PROTEIN CWF22-RELATED PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000002976.3|UniProtKB=F6Q562 F6Q562 PACC1 PTHR16087:SF0 TRANSMEMBRANE PROTEIN 206 PROTON-ACTIVATED CHLORIDE CHANNEL MONDO|Ensembl=ENSMODG00000004636.4|UniProtKB=A0A5F8GLR2 A0A5F8GLR2 STXBP1 PTHR11679:SF35 VESICLE PROTEIN SORTING-ASSOCIATED SYNTAXIN-BINDING PROTEIN 1 SNARE binding#GO:0000149;binding#GO:0005488;syntaxin binding#GO:0019905;protein binding#GO:0005515 establishment of organelle localization#GO:0051656;export from cell#GO:0140352;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular localization#GO:0051641;secretion by cell#GO:0032940;protein transport#GO:0015031;vesicle-mediated transport#GO:0016192;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;regulated exocytosis#GO:0045055;intracellular protein transport#GO:0006886;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;signal release#GO:0023061;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;macromolecule localization#GO:0033036;vesicle localization#GO:0051648;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;calcium-ion regulated exocytosis#GO:0017156;transport#GO:0006810;synaptic vesicle cycle#GO:0099504 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Munc18#P05770 MONDO|Ensembl=ENSMODG00000010343.4|UniProtKB=F6VNR9 F6VNR9 NBAS PTHR15922:SF2 NEUROBLASTOMA-AMPLIFIED SEQUENCE NBAS SUBUNIT OF NRZ TETHERING COMPLEX protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;endoplasmic reticulum protein-containing complex#GO:0140534 MONDO|Ensembl=ENSMODG00000001723.4|UniProtKB=F6XG94 F6XG94 PDGFC PTHR11633:SF5 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR C growth factor receptor binding#GO:0070851;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;positive regulation of locomotion#GO:0040017;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell motility#GO:2000147;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 Angiogenesis#P00005>PDGF#P00224 MONDO|Ensembl=ENSMODG00000015085.3|UniProtKB=F6S1V1 F6S1V1 PTHR10026:SF45 CYCLIN CYCLIN-L2 protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 kinase modulator#PC00140;kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000002862.4|UniProtKB=A0A5F8GK27 A0A5F8GK27 GRHPR PTHR10996:SF137 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000014045.3|UniProtKB=F6UPM5 F6UPM5 DRC3 PTHR45973:SF12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED DYNEIN REGULATORY COMPLEX SUBUNIT 3 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 MONDO|Ensembl=ENSMODG00000039958.1|UniProtKB=A0A5F8GYC2 A0A5F8GYC2 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000025710.3|UniProtKB=K7E5N0 K7E5N0 PTHR15228:SF7 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 29 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000012153.4|UniProtKB=F7CYS5 F7CYS5 MAPKAPK5 PTHR24349:SF179 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-ACTIVATED PROTEIN KINASE 5 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;calcium/calmodulin-dependent protein kinase activity#GO:0004683;binding#GO:0005488;kinase binding#GO:0019900;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;kinase activity#GO:0016301;transferase activity#GO:0016740;calmodulin binding#GO:0005516;mitogen-activated protein kinase binding#GO:0051019 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000021286.4|UniProtKB=A0A5F8G4X1 A0A5F8G4X1 MCF2L2 PTHR22826:SF201 RHO GUANINE EXCHANGE FACTOR-RELATED GUANINE NUCLEOTIDE EXCHANGE FACTOR MCF2L2-RELATED nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000016238.5|UniProtKB=F7FLJ3 F7FLJ3 ZMYND8 PTHR46453:SF3 PROTEIN KINASE C-BINDING PROTEIN 1 MYND-TYPE ZINC FINGER-CONTAINING CHROMATIN READER ZMYND8 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000023946.2|UniProtKB=F7BGD8 F7BGD8 ZBTB1 PTHR24399:SF21 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565 negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000000427.4|UniProtKB=F6VAE1 F6VAE1 NDST2 PTHR10605:SF53 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE 2 catalytic activity#GO:0003824;deacylase activity#GO:0160215;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;deacetylase activity#GO:0019213 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000038669.1|UniProtKB=A0A5F8GNZ8 A0A5F8GNZ8 PTHR23105:SF1 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN EL8 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000006314.4|UniProtKB=F7B3P6 F7B3P6 MYOF PTHR12546:SF55 FER-1-LIKE MYOFERLIN lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 wound healing#GO:0042060;anatomical structure development#GO:0048856;plasma membrane organization#GO:0007009;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;muscle structure development#GO:0061061;cell differentiation#GO:0030154;response to stimulus#GO:0050896;muscle cell differentiation#GO:0042692;cellular component organization#GO:0016043;muscle cell development#GO:0055001;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular process#GO:0009987;response to stress#GO:0006950;response to wounding#GO:0009611;membrane fusion#GO:0061025 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000013778.4|UniProtKB=A0A5F8GQV7 A0A5F8GQV7 PPARD PTHR24082:SF15 NUCLEAR HORMONE RECEPTOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 homeostatic process#GO:0042592;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of lipid metabolic process#GO:0019216;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;multicellular organismal-level homeostasis#GO:0048871;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;hormone-mediated signaling pathway#GO:0009755;negative regulation of DNA-templated transcription#GO:0045892;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;response to hormone#GO:0009725;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 C4 zinc finger nuclear receptor#PC00169 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 MONDO|Ensembl=ENSMODG00000024517.2|UniProtKB=A0A5F8GST6 A0A5F8GST6 PTRH2 PTHR12649:SF31 PEPTIDYL-TRNA HYDROLASE 2 PEPTIDYL-TRNA HYDROLASE 2, MITOCHONDRIAL hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 positive regulation of apoptotic process#GO:0043065;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000003044.3|UniProtKB=F6Q0A9 F6Q0A9 SPIC PTHR11849:SF17 ETS TRANSCRIPTION FACTOR SPI-C transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 Interleukin signaling pathway#P00036>Ets#P00989 MONDO|Ensembl=ENSMODG00000008368.3|UniProtKB=F7E472 F7E472 IPCEF1 PTHR12844:SF45 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CNK3_IPCEF1 FUSION PROTEIN-RELATED protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 synapse organization#GO:0050808;postsynaptic specialization organization#GO:0099084;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;postsynapse organization#GO:0099173;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cell junction#GO:0030054;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000011213.3|UniProtKB=F6SQ78 F6SQ78 PTHR28620:SF1 CENTROMERE PROTEIN V CENTROMERE PROTEIN V MONDO|Ensembl=ENSMODG00000019238.4|UniProtKB=F6RDI3 F6RDI3 ROR2 PTHR24416:SF132 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR2 catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transferase activity#GO:0016740;kinase activity#GO:0016301;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;Wnt-protein binding#GO:0017147;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;signaling receptor complex#GO:0043235;axon#GO:0030424 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000024888.2|UniProtKB=F6RZN5 F6RZN5 PTHR45624:SF56 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL CARNITINE_ACYLCARNITINE CARRIER PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;quaternary ammonium group transmembrane transporter activity#GO:0015651 transport#GO:0006810;intracellular transport#GO:0046907;transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;mitochondrial transport#GO:0006839 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 MONDO|Ensembl=ENSMODG00000005904.4|UniProtKB=F6XD49 F6XD49 XYLT1 PTHR46025:SF2 XYLOSYLTRANSFERASE OXT XYLOSYLTRANSFERASE 1 pentosyltransferase activity#GO:0016763;xylosyltransferase activity#GO:0042285;UDP-xylosyltransferase activity#GO:0035252;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194 carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;glycoprotein biosynthetic process#GO:0009101;protein O-linked glycosylation#GO:0006493;chondroitin sulfate proteoglycan metabolic process#GO:0050654;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238 transferase#PC00220 MONDO|Ensembl=ENSMODG00000028894.1|UniProtKB=K7E436 K7E436 PTHR23226:SF353 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000010908.4|UniProtKB=F7FIS9 F7FIS9 CDC27 PTHR12558:SF13 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 27 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 regulation of cell cycle process#GO:0010564;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of chromosome segregation#GO:0051983;metaphase/anaphase transition of cell cycle#GO:0044784;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;protein modification by small protein conjugation or removal#GO:0070647;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;modification-dependent macromolecule catabolic process#GO:0043632;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of chromosome organization#GO:0033044;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;cell cycle#GO:0007049;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cell division#GO:0051301;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;mitotic cell cycle phase transition#GO:0044772 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000013199.4|UniProtKB=F6PHM6 F6PHM6 OCRL PTHR11200:SF176 INOSITOL 5-PHOSPHATASE INOSITOL POLYPHOSPHATE 5-PHOSPHATASE OCRL catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 neuron projection#GO:0043005;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000020514.5|UniProtKB=H9H7L2 H9H7L2 BDH1 PTHR43313:SF25 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C D-BETA-HYDROXYBUTYRATE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000043755.1|UniProtKB=F6U0G3 F6U0G3 OR52N5 PTHR26450:SF18 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52N5 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000006603.4|UniProtKB=F6ZWY4 F6ZWY4 ATAD3A PTHR23075:SF0 PUTATIVE ATP-ASE ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 3A cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000024256.2|UniProtKB=F6ZUA9 F6ZUA9 LOC100017458 PTHR48018:SF14 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8B4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012029.2|UniProtKB=F7ALZ4 F7ALZ4 CTSB PTHR12411:SF16 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN B catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosome#GO:0005764;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000000139.4|UniProtKB=A0A5F8G5E9 A0A5F8G5E9 FAM76B PTHR46176:SF3 LD21662P PROTEIN FAM76B intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;membraneless organelle#GO:0043228;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000038283.1|UniProtKB=A0A5F8G676 A0A5F8G676 PSMG4 PTHR33559:SF1 PROTEASOME ASSEMBLY CHAPERONE 4 PROTEASOME ASSEMBLY CHAPERONE 4 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000024507.2|UniProtKB=A0A5F8HBV0 A0A5F8HBV0 OR4K5 PTHR48002:SF56 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K5 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000010513.4|UniProtKB=A0A5F8HC67 A0A5F8HC67 PRKDC PTHR11139:SF68 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;apoptotic signaling pathway#GO:0097190;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;DNA repair#GO:0006281;developmental process#GO:0032502;DNA damage response#GO:0006974;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;somatic cell DNA recombination#GO:0016444;macromolecule biosynthetic process#GO:0009059;cell communication#GO:0007154;anatomical structure development#GO:0048856;telomere organization#GO:0032200;system development#GO:0048731;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;somatic diversification of immune receptors#GO:0002200;cellular response to stimulus#GO:0051716;cell death#GO:0008219;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;gene expression#GO:0010467;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;response to stress#GO:0006950;signal transduction#GO:0007165;somatic recombination of immunoglobulin gene segments#GO:0016447;cellular process#GO:0009987;immune system development#GO:0002520;intrinsic apoptotic signaling pathway#GO:0097193;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;cellular response to stress#GO:0033554;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;response to stimulus#GO:0050896;production of molecular mediator of immune response#GO:0002440;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;V(D)J recombination#GO:0033151 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000011181.4|UniProtKB=F7E8D0 F7E8D0 FMNL1 PTHR45857:SF2 FORMIN-LIKE PROTEIN FORMIN-LIKE PROTEIN 1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 cell migration#GO:0016477;cell motility#GO:0048870;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000006380.4|UniProtKB=F6T160 F6T160 KCNAB2 PTHR43150:SF1 HYPERKINETIC, ISOFORM M VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-2 ion channel regulator activity#GO:0099106;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;molecular function regulator activity#GO:0098772;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;binding#GO:0005488;transmembrane transporter binding#GO:0044325;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;protein binding#GO:0005515;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;channel regulator activity#GO:0016247 biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062 axon#GO:0030424;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;cell periphery#GO:0071944;neuron projection#GO:0043005;main axon#GO:0044304;membrane#GO:0016020;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000019927.2|UniProtKB=F6V863 F6V863 PTHR48002:SF123 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4B1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018329.4|UniProtKB=A0A5F8G223 A0A5F8G223 PRMT8 PTHR11006:SF47 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 8 transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;histone modifying activity#GO:0140993 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000029588.2|UniProtKB=K7E0L8 K7E0L8 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000018021.3|UniProtKB=F7AJW2 F7AJW2 PTHR11673:SF34 TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 5A-1 translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 MONDO|Ensembl=ENSMODG00000041791.1|UniProtKB=A0A5F8GJF4 A0A5F8GJF4 MISP3 PTHR18839:SF4 MITOTIC INTERACTOR AND SUBSTRATE OF PLK1 MISP FAMILY MEMBER MISP FAMILY MEMBER 3 MONDO|Ensembl=ENSMODG00000009686.4|UniProtKB=F6YBI5 F6YBI5 AGPS PTHR46568:SF1 ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;peroxisome#GO:0005777 MONDO|Ensembl=ENSMODG00000020538.4|UniProtKB=F7EN90 F7EN90 KLHL5 PTHR24412:SF135 KELCH PROTEIN KELCH-LIKE PROTEIN 5 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000015886.4|UniProtKB=F6Q5X0 F6Q5X0 AHSG PTHR13814:SF6 FETUIN ALPHA-2-HS-GLYCOPROTEIN enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;inflammatory response#GO:0006954;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;acute inflammatory response#GO:0002526;response to stress#GO:0006950;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;regulation of bone mineralization#GO:0030500;regulation of multicellular organismal process#GO:0051239;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;defense response#GO:0006952 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000015580.4|UniProtKB=F6ZV60 F6ZV60 BABAM2 PTHR15189:SF8 BRISC AND BRCA1-A COMPLEX MEMBER 2 BRISC AND BRCA1-A COMPLEX MEMBER 2 response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 ubiquitin ligase complex#GO:0000151;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000000516.4|UniProtKB=F6Y5H8 F6Y5H8 DHX15 PTHR18934:SF95 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX15 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA helicase#PC00032;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000047196.1|UniProtKB=A0A5F8G2R7 A0A5F8G2R7 PTHR24256:SF521 TRYPTASE-RELATED TRYPTASE DELTA serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000040096.1|UniProtKB=K7E656 K7E656 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000016187.4|UniProtKB=F7FYG2 F7FYG2 RBPJL PTHR10665:SF2 RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS-LIKE PROTEIN DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 Alzheimer disease-presenilin pathway#P00004>CSL#P00158;Notch signaling pathway#P00045>Su(H)#P01101;Angiogenesis#P00005>CSL#P00233 MONDO|Ensembl=ENSMODG00000002025.4|UniProtKB=A0A5F8HCB8 A0A5F8HCB8 MED10 PTHR13345:SF13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 RNA metabolism protein#PC00031;general transcription factor#PC00259 MONDO|Ensembl=ENSMODG00000036472.1|UniProtKB=A0A5F8G7L4 A0A5F8G7L4 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000010245.3|UniProtKB=F6W6M1 F6W6M1 NDUFA1 PTHR17098:SF2 NADH-UBIQUINONE OXIDOREDUCTASE MWFE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 1 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000003951.4|UniProtKB=F7FYT4 F7FYT4 PLPPR5 PTHR10165:SF17 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 5 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;lipid modification#GO:0030258;cellular process#GO:0009987;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;cell communication#GO:0007154;dephosphorylation#GO:0016311;phosphate-containing compound metabolic process#GO:0006796;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 hydrolase#PC00121;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000013108.4|UniProtKB=F7BMZ5 F7BMZ5 CDC6 PTHR10763:SF26 CELL DIVISION CONTROL PROTEIN 6-RELATED DNA REPLICATION FACTOR CDC6 sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA replication origin binding#GO:0003688 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 replication origin binding protein#PC00199 MONDO|Ensembl=ENSMODG00000013102.5|UniProtKB=F7EX89 F7EX89 LRFN2 PTHR45842:SF6 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 2 postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;cell surface#GO:0009986;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 MONDO|Ensembl=ENSMODG00000047215.1|UniProtKB=A0A5F8GRU0 A0A5F8GRU0 SMIM15 PTHR28644:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 15 SMALL INTEGRAL MEMBRANE PROTEIN 15 MONDO|Ensembl=ENSMODG00000005736.3|UniProtKB=F6QEC4 F6QEC4 PTHR19343:SF0 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 23_DELTA VARIABLE 6 binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000040799.1|UniProtKB=A0A5F8H9L8 A0A5F8H9L8 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000009083.3|UniProtKB=A0A5F8GZ22 A0A5F8GZ22 AP2S1 PTHR11753:SF6 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-2 COMPLEX SUBUNIT SIGMA transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 vesicle coat protein#PC00235;membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000008558.4|UniProtKB=F7CXM6 F7CXM6 UBQLN1 PTHR10677:SF16 UBIQUILIN UBIQUILIN-1 protein binding#GO:0005515;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488 cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;process utilizing autophagic mechanism#GO:0061919;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;cellular component organization#GO:0016043;response to stimulus#GO:0050896;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of macroautophagy#GO:0016241;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;response to endoplasmic reticulum stress#GO:0034976;vacuole organization#GO:0007033;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;macroautophagy#GO:0016236 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000006158.3|UniProtKB=F7BS95 F7BS95 LOC130456421 PTHR18860:SF7 14-3-3 PROTEIN 14-3-3 PROTEIN ZETA_DELTA scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;PI3 kinase pathway#P00048>14-3-3#P01206;EGF receptor signaling pathway#P00018>14-3-3#P00539;FGF signaling pathway#P00021>14-3-3#P00624 MONDO|Ensembl=ENSMODG00000011467.6|UniProtKB=F6W0B1 F6W0B1 PTHR15528:SF5 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR-RELATED PROTEIN 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organismal-level homeostasis#GO:0048871;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000018536.3|UniProtKB=F7GD74 F7GD74 IRAK4 PTHR24419:SF35 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 phosphotransferase activity, alcohol group as acceptor#GO:0016773;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;cytokine-mediated signaling pathway#GO:0019221;lipopolysaccharide-mediated signaling pathway#GO:0031663;response to bacterium#GO:0009617;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;positive regulation of signal transduction#GO:0009967;cellular response to biotic stimulus#GO:0071216;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;mitotic cell cycle#GO:0000278;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;cellular response to lipopolysaccharide#GO:0071222;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>IRAK4#P01342 MONDO|Ensembl=ENSMODG00000046286.1|UniProtKB=A0A5F8G7B1 A0A5F8G7B1 PTHR12081:SF19 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F6 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000001228.5|UniProtKB=F7G7D5 F7G7D5 MYBL2 PTHR45614:SF30 MYB PROTEIN-RELATED MYB-RELATED PROTEIN B transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;cell cycle#GO:0007049;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 MONDO|Ensembl=ENSMODG00000036421.1|UniProtKB=A0A5F8GXG3 A0A5F8GXG3 PTHR47884:SF1 PROSTATE AND TESTIS EXPRESSED PROTEIN 2 PROSTATE AND TESTIS EXPRESSED PROTEIN 2 MONDO|Ensembl=ENSMODG00000005210.3|UniProtKB=F7A209 F7A209 PTHR21600:SF49 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE MITOCHONDRIAL MRNA PSEUDOURIDINE SYNTHASE RPUSD3 intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;isomerase activity#GO:0016853 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000019448.4|UniProtKB=F6RXG9 F6RXG9 ITGA1 PTHR23220:SF22 INTEGRIN ALPHA INTEGRIN ALPHA-1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154 membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;integrin complex#GO:0008305 integrin#PC00126;cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Integrin alpha#P00941;Gonadotropin-releasing hormone receptor pathway#P06664>alpha-beta integrin dimer#P06820 MONDO|Ensembl=ENSMODG00000004386.4|UniProtKB=F6SVV5 F6SVV5 LMAN2 PTHR12223:SF36 VESICULAR MANNOSE-BINDING LECTIN VESICULAR INTEGRAL-MEMBRANE PROTEIN VIP36 carbohydrate binding#GO:0030246;monosaccharide binding#GO:0048029;small molecule binding#GO:0036094;binding#GO:0005488 establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000048242.1|UniProtKB=A0A5F8GVM4 A0A5F8GVM4 PTHR13809:SF5 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-5-RELATED hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562;catalytic complex#GO:1902494;extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117 Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;GABA-B receptor II signaling#P05731>Ggamma#P05754;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Wnt signaling pathway#P00057>Ggamma#P01465;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Enkephalin release#P05913>G-Protein (s)#P05977;Enkephalin release#P05913>G-Protein (i)#P05974 MONDO|Ensembl=ENSMODG00000045035.1|UniProtKB=A0A5F8GW27 A0A5F8GW27 SUMF1 PTHR23150:SF37 SULFATASE MODIFYING FACTOR 1, 2 FORMYLGLYCINE-GENERATING ENZYME catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000000275.3|UniProtKB=H9H5V6 H9H5V6 RPL28 PTHR10544:SF0 60S RIBOSOMAL PROTEIN L28 LARGE RIBOSOMAL SUBUNIT PROTEIN EL28 cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000015380.4|UniProtKB=A0A5F8GL66 A0A5F8GL66 NOS1 PTHR19384:SF63 NITRIC OXIDE SYNTHASE-RELATED NITRIC OXIDE SYNTHASE 1 ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;monooxygenase activity#GO:0004497 response to lipopolysaccharide#GO:0032496;metabolic process#GO:0008152;response to chemical#GO:0042221;response to lipid#GO:0033993;arginine metabolic process#GO:0006525;intracellular signaling cassette#GO:0141124;response to biotic stimulus#GO:0009607;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of biological quality#GO:0065008;oxoacid metabolic process#GO:0043436;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;small molecule catabolic process#GO:0044282;response to endogenous stimulus#GO:0009719;carboxylic acid metabolic process#GO:0019752;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;response to external stimulus#GO:0009605;system process#GO:0003008;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;proteinogenic amino acid metabolic process#GO:0170039;biological regulation#GO:0065007;biosynthetic process#GO:0009058;response to other organism#GO:0051707;amino acid metabolic process#GO:0006520;regulation of blood pressure#GO:0008217;carboxylic acid catabolic process#GO:0046395;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to bacterium#GO:0009617;circulatory system process#GO:0003013;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;cell junction#GO:0030054;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;postsynapse#GO:0098794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Gonadotropin-releasing hormone receptor pathway#P06664>NOSI#G06888;Gonadotropin-releasing hormone receptor pathway#P06664>NOSI#P06741;CCKR signaling map#P06959>NOS1#P07158 MONDO|Ensembl=ENSMODG00000012386.3|UniProtKB=F6PNL3 F6PNL3 CYB5A PTHR19359:SF160 CYTOCHROME B5 CYTOCHROME B5 binding#GO:0005488;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000011697.3|UniProtKB=F7GDY5 F7GDY5 BMP10 PTHR11848:SF39 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 10 cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000019013.4|UniProtKB=F7C5X4 F7C5X4 PTHR15929:SF0 STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000012759.2|UniProtKB=A0A5F8G7B5 A0A5F8G7B5 SURF1 PTHR23427:SF15 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 1 mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000038113.1|UniProtKB=A0A5F8H7X5 A0A5F8H7X5 JCHAIN PTHR10070:SF2 IMMUNOGLOBULIN J CHAIN IMMUNOGLOBULIN J CHAIN signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 response to stimulus#GO:0050896;immune system process#GO:0002376;humoral immune response#GO:0006959;immune response#GO:0006955 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000009018.4|UniProtKB=F7BPN2 F7BPN2 COMMD4 PTHR16231:SF4 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 4 MONDO|Ensembl=ENSMODG00000006899.3|UniProtKB=H9H688 H9H688 PTHR24247:SF236 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 6 G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 MONDO|Ensembl=ENSMODG00000006238.3|UniProtKB=F7FS07 F7FS07 GZF1 PTHR24393:SF150 ZINC FINGER PROTEIN GDNF-INDUCIBLE ZINC FINGER PROTEIN 1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000009303.5|UniProtKB=F6YX28 F6YX28 SP9 PTHR23235:SF26 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP9 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000016690.4|UniProtKB=A0A5F8GKK7 A0A5F8GKK7 LSM14B PTHR13586:SF1 SCD6 PROTEIN-RELATED PROTEIN LSM14 HOMOLOG B RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;P-body assembly#GO:0033962;cellular process#GO:0009987;cytoplasmic stress granule assembly#GO:0034063;cellular component assembly#GO:0022607 supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000006606.4|UniProtKB=A0A5F8GVE6 A0A5F8GVE6 HNRNPC PTHR13968:SF3 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS C1_C2 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000007768.4|UniProtKB=A0A5F8H2H5 A0A5F8H2H5 ACOT9 PTHR12655:SF10 ACYL-COA THIOESTERASE ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL hydrolase activity#GO:0016787;acyl-CoA hydrolase activity#GO:0016289;catalytic activity#GO:0003824;deacylase activity#GO:0160215;fatty acyl-CoA hydrolase activity#GO:0047617;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790 sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 esterase#PC00097;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000002178.4|UniProtKB=F7GEG5 F7GEG5 HCFC2 PTHR46003:SF2 HOST CELL FACTOR HOST CELL FACTOR 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000007759.3|UniProtKB=F7BJA6 F7BJA6 PTHR15254:SF2 FANCONI ANEMIA GROUP G PROTEIN FAMILY MEMBER FANCONI ANEMIA GROUP G PROTEIN response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stress#GO:0006950 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;Fanconi anaemia nuclear complex#GO:0043240 MONDO|Ensembl=ENSMODG00000015810.4|UniProtKB=A0A5F8HAE7 A0A5F8HAE7 PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;antigen binding#GO:0003823;peptide binding#GO:0042277 regulation of biological process#GO:0050789;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of adaptive immune response#GO:0002821;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;regulation of cell killing#GO:0031341;regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte mediated immunity#GO:0002705 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000016773.3|UniProtKB=F7GGA7 F7GGA7 PTHR43128:SF10 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A CHAIN oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;energy derivation by oxidation of organic compounds#GO:0015980;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid catabolic process#GO:0072329 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000024411.2|UniProtKB=F7GG30 F7GG30 LOC100619987 PTHR48002:SF123 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4B1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012614.3|UniProtKB=F6S2Q4 F6S2Q4 PSMB3 PTHR11599:SF62 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-3 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;proteasome complex#GO:0000502;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 MONDO|Ensembl=ENSMODG00000011724.4|UniProtKB=F7FSY2 F7FSY2 DNAJC13 PTHR36983:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 13 DNAJ HOMOLOG SUBFAMILY C MEMBER 13 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 receptor-mediated endocytosis#GO:0006898;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000038809.1|UniProtKB=A0A5F8GSQ3 A0A5F8GSQ3 PTHR34763:SF1 PROTEIN FAM104A PROTEIN VCF1 MONDO|Ensembl=ENSMODG00000036464.1|UniProtKB=A0A5F8GH01 A0A5F8GH01 PTHR42748:SF10 NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER NMRA-LIKE FAMILY DOMAIN-CONTAINING PROTEIN 1 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000042943.1|UniProtKB=A0A5F8GJG6 A0A5F8GJG6 LOC100617100 PTHR48002:SF76 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C11 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019431.3|UniProtKB=A0A5F8H4P0 A0A5F8H4P0 MINAR1 PTHR31530:SF2 MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1 MINAR1 FAMILY MEMBER MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1 regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;regulation of cell population proliferation#GO:0042127;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of TOR signaling#GO:0032006;negative regulation of cell population proliferation#GO:0008285;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004471.4|UniProtKB=F6Z2M4 F6Z2M4 TRPV4 PTHR10582:SF4 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 4 metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 establishment of localization#GO:0051234;actin filament organization#GO:0007015;inorganic cation import across plasma membrane#GO:0098659;response to osmotic stress#GO:0006970;transport#GO:0006810;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;supramolecular fiber organization#GO:0097435;intracellular signal transduction#GO:0035556;cellular response to osmotic stress#GO:0071470;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;osmosensory signaling pathway#GO:0007231;cellular response to stimulus#GO:0051716;calcium ion import#GO:0070509;cellular component organization or biogenesis#GO:0071840;cellular response to chemical stress#GO:0062197;calcium ion transmembrane import into cytosol#GO:0097553;cellular response to abiotic stimulus#GO:0071214;import into cell#GO:0098657;calcium ion transport#GO:0006816;response to chemical#GO:0042221;cytoskeleton organization#GO:0007010;monoatomic cation transmembrane transport#GO:0098655;organelle organization#GO:0006996;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;import across plasma membrane#GO:0098739;signaling#GO:0023052;calcium ion transmembrane transport#GO:0070588;response to abiotic stimulus#GO:0009628;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 transporter#PC00227;ion channel#PC00133 MONDO|Ensembl=ENSMODG00000045817.1|UniProtKB=A0A5F8GJN0 A0A5F8GJN0 PTHR10903:SF144 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 6 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000037582.1|UniProtKB=A0A5F8HBW7 A0A5F8HBW7 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010694.4|UniProtKB=F7GHA0 F7GHA0 VN2R597 PTHR24061:SF545 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 120-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000012657.3|UniProtKB=F6VYH1 F6VYH1 CDK13 PTHR24056:SF459 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 13 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911;transferase complex#GO:1990234;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000003524.4|UniProtKB=A0A5F8GIU8 A0A5F8GIU8 LOC103102197 PTHR24377:SF1053 IP01015P-RELATED ZINC FINGER PROTEIN 454 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004565.3|UniProtKB=F6R551 F6R551 FBXO24 PTHR47004:SF1 F-BOX ONLY PROTEIN 24 F-BOX ONLY PROTEIN 24 MONDO|Ensembl=ENSMODG00000027364.2|UniProtKB=K7E4F9 K7E4F9 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000011539.4|UniProtKB=A0A5F8G8H1 A0A5F8G8H1 RAD23A PTHR10621:SF29 UV EXCISION REPAIR PROTEIN RAD23 LYSINE-SPECIFIC DEMETHYLASE RAD23A protein-containing complex binding#GO:0044877;protein binding#GO:0005515;ubiquitin binding#GO:0043130;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;modification-dependent protein binding#GO:0140030 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytosol#GO:0005829 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 MONDO|Ensembl=ENSMODG00000018145.2|UniProtKB=F7CXD0 F7CXD0 GNB3 PTHR19850:SF31 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(T) SUBUNIT BETA-3 signaling adaptor activity#GO:0035591;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562 G-protein#PC00020;heterotrimeric G-protein#PC00117;protein-binding activity modulator#PC00095 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Enkephalin release#P05913>G-Protein (i)#P05974;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;GABA-B receptor II signaling#P05731>Gbeta#P05755;Enkephalin release#P05913>G-Protein (s)#P05977;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;Endogenous cannabinoid signaling#P05730>Gbeta#P05745;PI3 kinase pathway#P00048>Gbetagamma#P01188;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Wnt signaling pathway#P00057>GBeta#P01457;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743 MONDO|Ensembl=ENSMODG00000017065.3|UniProtKB=F6XHE8 F6XHE8 CPOX PTHR10755:SF0 COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 porphyrin-containing compound biosynthetic process#GO:0006779;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;tetrapyrrole biosynthetic process#GO:0033014;cellular process#GO:0009987;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxidase#PC00175;oxidoreductase#PC00176 Heme biosynthesis#P02746>Coproporphyrinogen Oxidase (oxygen dependent)#P02980 MONDO|Ensembl=ENSMODG00000038854.1|UniProtKB=K7E5H6 K7E5H6 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000037009.1|UniProtKB=A0A5F8GZB7 A0A5F8GZB7 SEC61G PTHR12309:SF5 SEC61 GAMMA SUBUNIT PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA transmembrane protein transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;establishment of protein localization to endoplasmic reticulum#GO:0072599;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;protein transport#GO:0015031;post-translational protein targeting to membrane, translocation#GO:0031204;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;localization within membrane#GO:0051668;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620 membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;rough endoplasmic reticulum#GO:0005791 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000041668.1|UniProtKB=A0A5F8GP58 A0A5F8GP58 PTHR13596:SF2 SMALL EDRK-RICH FACTOR 1 SMALL EDRK-RICH FACTOR 2 MONDO|Ensembl=ENSMODG00000006505.5|UniProtKB=F7EK18 F7EK18 PLPPR2 PTHR10165:SF15 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 2 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular response to stimulus#GO:0051716;phospholipid dephosphorylation#GO:0046839;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;cell communication#GO:0007154;dephosphorylation#GO:0016311 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 phosphatase#PC00181;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000002621.4|UniProtKB=F7FUH3 F7FUH3 HHAT PTHR13285:SF20 ACYLTRANSFERASE PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE HHAT acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;metabolic process#GO:0008152;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 MONDO|Ensembl=ENSMODG00000047710.1|UniProtKB=A0A5F8G533 A0A5F8G533 PTHR12521:SF0 PROTEIN C6ORF130 ADP-RIBOSE GLYCOHYDROLASE OARD1 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;purine nucleoside metabolic process#GO:0042278 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;chromosome#GO:0005694;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000011669.4|UniProtKB=A0A5F8GUC5 A0A5F8GUC5 SAMD4A PTHR12515:SF8 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED PROTEIN SMAUG HOMOLOG 1 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;positive regulation of macromolecule metabolic process#GO:0010604;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000003195.4|UniProtKB=A0A5F8GTN5 A0A5F8GTN5 PTHR48015:SF12 SERINE/THREONINE-PROTEIN KINASE TAO NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000001108.3|UniProtKB=F7DPG2 F7DPG2 UHRF1 PTHR14140:SF2 E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED E3 UBIQUITIN-PROTEIN LIGASE UHRF1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;protein modification by small protein conjugation or removal#GO:0070647;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000009714.3|UniProtKB=F7AAS0 F7AAS0 LOC100618020 PTHR24393:SF100 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 345-RELATED transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000013574.4|UniProtKB=F7BHW4 F7BHW4 NKTR PTHR11071:SF257 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NK-TUMOR RECOGNITION PROTEIN membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000051534.1|UniProtKB=A0A5F8GQ38 A0A5F8GQ38 LOC100022881 PTHR26450:SF12 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001915.3|UniProtKB=F6W153 F6W153 RAB7B PTHR47981:SF22 RAB FAMILY RAS-RELATED PROTEIN RAB-7B hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 vacuolar transport#GO:0007034;lytic vacuole organization#GO:0080171;transport#GO:0006810;phagolysosome assembly#GO:0001845;phagocytosis#GO:0006909;intracellular transport#GO:0046907;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lysosome organization#GO:0007040;membrane fusion#GO:0061025;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;lysosomal transport#GO:0007041;endosome to lysosome transport#GO:0008333;organelle assembly#GO:0070925;vacuole organization#GO:0007033;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;vesicle fusion#GO:0006906;endocytosis#GO:0006897 membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole#GO:0000323;vacuole#GO:0005773;cytoplasm#GO:0005737;late endosome#GO:0005770;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335 small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000024579.2|UniProtKB=F7B6K1 F7B6K1 LOC100030121 PTHR48018:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 974 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of smell#GO:0007608;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003225.4|UniProtKB=F7B9G7 F7B9G7 LOC100031975 PTHR24300:SF177 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2J2 tetrapyrrole binding#GO:0046906;binding#GO:0005488;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to stimulus#GO:0050896;response to chemical#GO:0042221;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410 membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000041313.1|UniProtKB=K7E2I1 K7E2I1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000011222.4|UniProtKB=F7E7T1 F7E7T1 PLCD3 PTHR10336:SF33 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA-3 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;hydrolase activity#GO:0016787;lipase activity#GO:0016298 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;phospholipase#PC00186;lipase#PC00143;hydrolase#PC00121 5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 MONDO|Ensembl=ENSMODG00000012547.4|UniProtKB=F6PM30 F6PM30 FRRS1L PTHR46902:SF1 DOMON DOMAIN-CONTAINING PROTEIN FRRS1L DOMON DOMAIN-CONTAINING PROTEIN FRRS1L regulation of biological quality#GO:0065008;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 MONDO|Ensembl=ENSMODG00000039152.1|UniProtKB=A0A5F8GV41 A0A5F8GV41 PTHR33064:SF29 POL PROTEIN LRRGT00076 MONDO|Ensembl=ENSMODG00000011492.4|UniProtKB=A0A5F8HHD6 A0A5F8HHD6 NXT2 PTHR12612:SF9 NUCLEAR TRANSPORT FACTOR 2 NTF2-RELATED EXPORT PROTEIN 2-RELATED gene expression#GO:0010467;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;transport#GO:0006810;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913 nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 MONDO|Ensembl=ENSMODG00000019556.4|UniProtKB=F6UTE3 F6UTE3 PTHR11328:SF31 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN SODIUM-DEPENDENT LYSOPHOSPHATIDYLCHOLINE SYMPORTER 1 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;lipid localization#GO:0010876;transport#GO:0006810;lipid transport#GO:0006869;macromolecule localization#GO:0033036;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000002435.4|UniProtKB=F7DZV7 F7DZV7 TLL1 PTHR10127:SF860 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING TOLLOID-LIKE PROTEIN 1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;regionalization#GO:0003002;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;developmental process#GO:0032502;metabolic process#GO:0008152;dorsal/ventral pattern formation#GO:0009953;primary metabolic process#GO:0044238;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;pattern specification process#GO:0007389;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000011788.4|UniProtKB=A0A5F8GTA5 A0A5F8GTA5 BTRC PTHR44156:SF2 SUPERNUMERARY LIMBS, ISOFORM B-RELATED F-BOX_WD REPEAT-CONTAINING PROTEIN 1A ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;regulation of protein catabolic process#GO:0042176;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498 ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 Hedgehog signaling pathway#P00025>Slimb#P00683;Wnt signaling pathway#P00057>betaTrCP#P01454 MONDO|Ensembl=ENSMODG00000014156.4|UniProtKB=F6X2X9 F6X2X9 PPM1D PTHR47992:SF253 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1D mitogen-activated protein kinase binding#GO:0051019;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488 negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 protein modifying enzyme#PC00260;protein phosphatase#PC00195 p53 pathway feedback loops 2#P04398>WIP-1#G04708;p53 pathway#P00059>WIP-1#G04693;p53 pathway feedback loops 2#P04398>WIP-1#P04650 MONDO|Ensembl=ENSMODG00000046121.1|UniProtKB=A0A5F8G6X8 A0A5F8G6X8 PTHR24377:SF878 IP01015P-RELATED ZINC FINGER PROTEIN 670 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000023467.3|UniProtKB=F6SIG8 F6SIG8 LOC100620011 PTHR24377:SF1038 IP01015P-RELATED ZINC FINGER PROTEIN 333 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004184.4|UniProtKB=F6YA72 F6YA72 LOC100023248 PTHR11431:SF134 FERRITIN FERRITIN HEAVY CHAIN iron ion binding#GO:0005506;ferrous iron binding#GO:0008198;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 storage protein#PC00210 MONDO|Ensembl=ENSMODG00000047791.1|UniProtKB=A0A5F8H6T6 A0A5F8H6T6 PTHR19424:SF3 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR-BINDING PROTEIN 1 cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950;heat acclimation#GO:0010286;response to heat#GO:0009408;cellular response to heat#GO:0034605;response to temperature stimulus#GO:0009266;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000016448.3|UniProtKB=F7A479 F7A479 BMP7 PTHR11848:SF135 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 7 cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP7#G06687;Gonadotropin-releasing hormone receptor pathway#P06664>BMP7#G06901;Gonadotropin-releasing hormone receptor pathway#P06664>BMP6/7#P06752;TGF-beta signaling pathway#P00052>TGFbeta#P01286 MONDO|Ensembl=ENSMODG00000027607.2|UniProtKB=K7E5Y6 K7E5Y6 TMEM241 PTHR11132:SF565 SOLUTE CARRIER FAMILY 35 UDP-N-ACETYLGLUCOSAMINE TRANSPORTER SLC35D4 nucleotide-sugar transmembrane transporter activity#GO:0005338;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000012305.4|UniProtKB=F7EJ21 F7EJ21 MOB4 PTHR22599:SF1 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB-LIKE PROTEIN PHOCEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase activator#PC00138 MONDO|Ensembl=ENSMODG00000044141.1|UniProtKB=A0A5F8H0A8 A0A5F8H0A8 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000008513.4|UniProtKB=F7CD41 F7CD41 DKK3 PTHR12113:SF8 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 3 binding#GO:0005488;signaling receptor regulator activity#GO:0030545;signaling receptor inhibitor activity#GO:0030547;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000000022.4|UniProtKB=F6S0H7 F6S0H7 LOC100032946 PTHR44813:SF1 MITOGEN-ACTIVATED PROTEIN KINASE-BINDING PROTEIN 1 MITOGEN-ACTIVATED PROTEIN KINASE-BINDING PROTEIN 1 MONDO|Ensembl=ENSMODG00000002679.3|UniProtKB=F7CYW1 F7CYW1 PTHR11905:SF20 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 8 protein binding#GO:0005515;hydrolase activity#GO:0016787;binding#GO:0005488;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;cell adhesion molecule binding#GO:0050839 positive regulation of protein metabolic process#GO:0051247;proteolysis#GO:0006508;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;response to stimulus#GO:0050896;regulation of proteolysis#GO:0030162;metabolic process#GO:0008152;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;positive regulation of macromolecule metabolic process#GO:0010604;inflammatory response#GO:0006954;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;protein metabolic process#GO:0019538;regulation of cell motility#GO:2000145;primary metabolic process#GO:0044238;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of leukocyte migration#GO:0002685;regulation of macromolecule metabolic process#GO:0060255;regulation of cell migration#GO:0030334;regulation of catabolic process#GO:0009894;defense response#GO:0006952;positive regulation of locomotion#GO:0040017;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000001497.3|UniProtKB=F7AQW1 F7AQW1 TGFB1I1 PTHR24216:SF27 PAXILLIN-RELATED TRANSFORMING GROWTH FACTOR BETA-1-INDUCED TRANSCRIPT 1 PROTEIN transcription coactivator activity#GO:0003713;protein sequestering activity#GO:0140311;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular sequestering activity#GO:0140313 cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;anchoring junction#GO:0070161 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 Angiogenesis#P00005>Paxillin#P00194;VEGF signaling pathway#P00056>Paxillin#P01418 MONDO|Ensembl=ENSMODG00000013982.4|UniProtKB=A0A5F8GPN1 A0A5F8GPN1 LOC100013496 PTHR11730:SF43 AMMONIUM TRANSPORTER BLOOD GROUP RH(D) POLYPEPTIDE channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 homeostatic process#GO:0042592;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000010944.4|UniProtKB=A0A5F8GE76 A0A5F8GE76 FOXH1 PTHR47316:SF1 FORKHEAD BOX PROTEIN H1 FORKHEAD BOX PROTEIN H1 winged helix/forkhead transcription factor#PC00246 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 MONDO|Ensembl=ENSMODG00000014335.3|UniProtKB=F6UM96 F6UM96 LOC100617106 PTHR47958:SF195 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000004414.3|UniProtKB=A0A5F8GZC1 A0A5F8GZC1 BPNT1 PTHR43028:SF5 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000024773.3|UniProtKB=F7CQL8 F7CQL8 PTHR48482:SF3 INTERLEUKIN-19-RELATED INTERLEUKIN-19 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000038455.1|UniProtKB=A0A5F8GH02 A0A5F8GH02 ASB7 PTHR24126:SF24 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 10 MONDO|Ensembl=ENSMODG00000036725.1|UniProtKB=F6Q121 F6Q121 LOC100023334 PTHR26450:SF89 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52B4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000018785.4|UniProtKB=F7AD67 F7AD67 PTHR10269:SF1 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-LIKE molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;system development#GO:0048731;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;side of membrane#GO:0098552 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000019445.4|UniProtKB=F6RY10 F6RY10 MAPRE1 PTHR10623:SF20 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER MICROTUBULE-ASSOCIATED PROTEIN RP_EB FAMILY MEMBER 1 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;intracellular protein localization#GO:0008104;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;spindle assembly#GO:0051225;cellular process#GO:0009987;protein localization to microtubule cytoskeleton#GO:0072698;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;organelle assembly#GO:0070925;regulation of microtubule-based process#GO:0032886;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365 microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;cytoplasmic microtubule#GO:0005881;microtubule end#GO:1990752;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;microtubule#GO:0005874;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 MONDO|Ensembl=ENSMODG00000048395.1|UniProtKB=A0A5F8H7H2 A0A5F8H7H2 CEBPZOS PTHR38001:SF1 PROTEIN CEBPZOS PROTEIN CEBPZOS MONDO|Ensembl=ENSMODG00000007897.4|UniProtKB=F6YT61 F6YT61 PTHR46315:SF1 SPERMINE SYNTHASE SPERMINE SYNTHASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 polyamine metabolic process#GO:0006595;cellular process#GO:0009987;metabolic process#GO:0008152;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596 MONDO|Ensembl=ENSMODG00000006765.2|UniProtKB=A0A5F8GI03 A0A5F8GI03 PTHR10210:SF123 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 MONDO|Ensembl=ENSMODG00000024505.2|UniProtKB=F7C665 F7C665 LOC100029032 PTHR24242:SF369 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000010047.4|UniProtKB=F6TT94 F6TT94 TLCD3A PTHR13439:SF20 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 3A chemical homeostasis#GO:0048878;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000004078.3|UniProtKB=F6VW29 F6VW29 ACER2 PTHR46139:SF1 ALKALINE CERAMIDASE ALKALINE CERAMIDASE 2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 sphingoid biosynthetic process#GO:0046520;ceramide metabolic process#GO:0006672;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;alcohol biosynthetic process#GO:0046165;lipid catabolic process#GO:0016042;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000021048.4|UniProtKB=A0A5F8GUK6 A0A5F8GUK6 SETD4 PTHR13271:SF164 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE SET DOMAIN-CONTAINING PROTEIN 4 lysine N-methyltransferase activity#GO:0016278;histone H3K4 methyltransferase activity#GO:0042800;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276 chromatin remodeling#GO:0006338;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;biological regulation#GO:0065007;chromatin organization#GO:0006325;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;positive regulation of response to external stimulus#GO:0032103;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of inflammatory response#GO:0050729 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 methyltransferase#PC00155;transferase#PC00220 MONDO|Ensembl=ENSMODG00000007616.4|UniProtKB=F7C5B6 F7C5B6 ASRGL1 PTHR10188:SF41 L-ASPARAGINASE ISOASPARTYL PEPTIDASE_L-ASPARAGINASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;amidase activity#GO:0004040 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000024502.1|UniProtKB=F7B7Z1 F7B7Z1 LOC100029152 PTHR24242:SF227 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000004093.3|UniProtKB=F6VVN7 F6VVN7 FGF19 PTHR11486:SF74 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 19 binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;fibroblast growth factor receptor binding#GO:0005104 cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;system development#GO:0048731 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000015231.4|UniProtKB=F6V2U9 F6V2U9 BICDL1 PTHR32123:SF12 BICD FAMILY-LIKE CARGO ADAPTER BICD FAMILY-LIKE CARGO ADAPTER 1 microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;vesicle cytoskeletal trafficking#GO:0099518 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000008126.4|UniProtKB=F7ELW8 F7ELW8 USP44 PTHR21646:SF15 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 44 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of cellular process#GO:0050794;regulation of biological quality#GO:0065008;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of biological process#GO:0050789;regulation of protein stability#GO:0031647 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000041310.1|UniProtKB=A0A5F8GD33 A0A5F8GD33 PTHR24103:SF676 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000023229.3|UniProtKB=F6VEG3 F6VEG3 PTHR20886:SF10 VANG-LIKE PROTEIN VANG-LIKE PROTEIN 2 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;tissue development#GO:0009888;epithelium development#GO:0060429;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;morphogenesis of an epithelium#GO:0002009;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;non-canonical Wnt signaling pathway#GO:0035567;signaling#GO:0023052;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;cell communication#GO:0007154;tissue morphogenesis#GO:0048729 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000015914.4|UniProtKB=F6ZRP2 F6ZRP2 TRIM35 PTHR24103:SF665 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM35 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 immune response#GO:0006955;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;biological regulation#GO:0065007;response to other organism#GO:0051707;defense response to other organism#GO:0098542;regulation of apoptotic process#GO:0042981;response to external stimulus#GO:0009605;defense response#GO:0006952;positive regulation of apoptotic process#GO:0043065;innate immune response#GO:0045087;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000011163.4|UniProtKB=A0A5F8HEK1 A0A5F8HEK1 PTHR15427:SF6 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER MULTIMERIN-2 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;negative regulation of biological process#GO:0048519;blood vessel morphogenesis#GO:0048514;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;developmental process#GO:0032502;cell adhesion mediated by integrin#GO:0033627;negative regulation of cellular process#GO:0048523;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;cellular process#GO:0009987;negative regulation of cell population proliferation#GO:0008285;biological regulation#GO:0065007;tube development#GO:0035295;multicellular organismal process#GO:0032501 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000017806.4|UniProtKB=F6ZY23 F6ZY23 TP53BP1 PTHR15321:SF3 TUMOR SUPPRESSOR P53-BINDING PROTEIN 1 TP53-BINDING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular response to stress#GO:0033554;cell cycle checkpoint signaling#GO:0000075;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;DNA metabolic process#GO:0006259;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of cell cycle phase transition#GO:1901987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA damage checkpoint signaling#GO:0000077;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;DNA integrity checkpoint signaling#GO:0031570;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000038752.1|UniProtKB=A0A5F8HDB6 A0A5F8HDB6 C2H17orf58 PTHR35967:SF1 UPF0450 PROTEIN C17ORF58 UPF0450 PROTEIN C17ORF58 MONDO|Ensembl=ENSMODG00000019263.4|UniProtKB=A0A5F8H766 A0A5F8H766 SYK PTHR24418:SF231 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SYK catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of immune response#GO:0050776;cell activation#GO:0001775;cell communication#GO:0007154;positive regulation of cell adhesion#GO:0045785;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cell adhesion mediated by integrin#GO:0033628;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;macrophage activation#GO:0042116;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;adaptive immune response#GO:0002250;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;immune system process#GO:0002376;cell activation involved in immune response#GO:0002263;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;response to stimulus#GO:0050896;leukocyte activation involved in immune response#GO:0002366;immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;B cell receptor signaling pathway#GO:0050853;positive regulation of immune system process#GO:0002684;antigen receptor-mediated signaling pathway#GO:0050851;myeloid leukocyte activation#GO:0002274 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 B cell activation#P00010>Syk#P00382 MONDO|Ensembl=ENSMODG00000016431.4|UniProtKB=F7ASD9 F7ASD9 TIGD7 PTHR19303:SF17 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 7 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000010646.4|UniProtKB=F7D4J2 F7D4J2 LOC100028858 PTHR11662:SF459 SOLUTE CARRIER FAMILY 17 SIALIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000001880.4|UniProtKB=F6V0G1 F6V0G1 LOC100014233 PTHR24376:SF185 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 786 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000013775.3|UniProtKB=F6TVQ1 F6TVQ1 TBL2 PTHR44321:SF1 TRANSDUCIN BETA-LIKE PROTEIN 2 TRANSDUCIN BETA-LIKE PROTEIN 2 cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000007907.4|UniProtKB=A0A5F8HD95 A0A5F8HD95 ATP10B PTHR24092:SF79 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE VB intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657 lipid transport#GO:0006869;phospholipid transport#GO:0015914;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000005462.4|UniProtKB=F7CGH7 F7CGH7 POMT2 PTHR10050:SF46 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE 2 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 transferase#PC00220;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000045179.1|UniProtKB=A0A5F8GV36 A0A5F8GV36 PTHR20515:SF20 BETA-DEFENSIN GALLINACIN-1-RELATED signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488 cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;response to other organism#GO:0051707;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response#GO:0006952;response to external stimulus#GO:0009605;cell motility#GO:0048870;response to stimulus#GO:0050896;locomotion#GO:0040011;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;cellular response to stimulus#GO:0051716;cell chemotaxis#GO:0060326;cellular response to chemical stimulus#GO:0070887;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;chemotaxis#GO:0006935 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;antimicrobial response protein#PC00051 MONDO|Ensembl=ENSMODG00000044705.1|UniProtKB=K7DZ07 K7DZ07 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000019866.3|UniProtKB=A0A5F8HIB5 A0A5F8HIB5 PTHR11740:SF45 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Parkinson disease#P00049>Casein kinase II#P01236 MONDO|Ensembl=ENSMODG00000049991.1|UniProtKB=A0A5F8HDV2 A0A5F8HDV2 CFAP161 PTHR24274:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000014713.4|UniProtKB=F7D2Z8 F7D2Z8 PTHR19944:SF59 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ ALPHA 1 CHAIN binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823;protein-containing complex binding#GO:0044877 cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of lymphocyte activation#GO:0051249;immune system process#GO:0002376;positive regulation of immune system process#GO:0002684;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of T cell activation#GO:0050863;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;positive regulation of leukocyte activation#GO:0002696;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;positive regulation of cell adhesion#GO:0045785;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte activation#GO:0051251;positive regulation of cellular process#GO:0048522;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778 late endosome membrane#GO:0031902;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;protein-containing complex#GO:0032991;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 MONDO|Ensembl=ENSMODG00000005039.4|UniProtKB=A0A5F8GQ91 A0A5F8GQ91 ADAMTSL5 PTHR13723:SF173 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 5 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000001399.4|UniProtKB=F6ZA76 F6ZA76 PTHR11819:SF96 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000005932.4|UniProtKB=A0A5F8HJP8 A0A5F8HJP8 CETN2 PTHR23050:SF218 CALCIUM BINDING PROTEIN CENTRIN-1 calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;centriole replication#GO:0007099;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226 intracellular membrane-bounded organelle#GO:0043231;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813 calcium-binding protein#PC00060;calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000049418.1|UniProtKB=A0A5F8HES3 A0A5F8HES3 NEMP1 PTHR13598:SF2 AT07567P-RELATED NUCLEAR ENVELOPE INTEGRAL MEMBRANE PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000041908.1|UniProtKB=A0A5F8H3Y4 A0A5F8H3Y4 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000014926.4|UniProtKB=F7FVH3 F7FVH3 RARB PTHR24082:SF286 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR BETA DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;intracellular receptor signaling pathway#GO:0030522;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;response to hormone#GO:0009725;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;negative regulation of DNA-templated transcription#GO:0045892;hormone-mediated signaling pathway#GO:0009755;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 C4 zinc finger nuclear receptor#PC00169 MONDO|Ensembl=ENSMODG00000027441.2|UniProtKB=A0A5F8HIC9 A0A5F8HIC9 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 MONDO|Ensembl=ENSMODG00000048068.1|UniProtKB=A0A5F8G6M6 A0A5F8G6M6 PTHR23304:SF189 SPOT2-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000004834.4|UniProtKB=A0A5F8H5M1 A0A5F8H5M1 TRIP6 PTHR24212:SF7 ZYXIN/TRIP6 THYROID RECEPTOR-INTERACTING PROTEIN 6 positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;positive regulation of signal transduction#GO:0009967;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224 stress fiber#GO:0001725;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;actomyosin#GO:0042641;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000050357.1|UniProtKB=F6SN28 F6SN28 LOC100025365 PTHR23303:SF14 CARBOXYPEPTIDASE REGULATORY REGION-CONTAINING BOS COMPLEX SUBUNIT NOMO1-RELATED nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 MONDO|Ensembl=ENSMODG00000016503.4|UniProtKB=F7EQI5 F7EQI5 ATAD1 PTHR45644:SF2 AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED OUTER MITOCHONDRIAL TRANSMEMBRANE HELIX TRANSLOCASE localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization within membrane#GO:0051668;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150 MONDO|Ensembl=ENSMODG00000029751.2|UniProtKB=K7E4I4 K7E4I4 UBAP1L PTHR15960:SF3 LD44032P UBIQUITIN-ASSOCIATED PROTEIN 1-LIKE protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;ESCRT I complex#GO:0000813;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505 MONDO|Ensembl=ENSMODG00000042806.1|UniProtKB=A0A5F8GSH0 A0A5F8GSH0 MTPN PTHR24189:SF69 MYOTROPHIN MYOTROPHIN cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of actin filament depolymerization#GO:0030834;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000050868.1|UniProtKB=A0A5F8H5Z7 A0A5F8H5Z7 PTHR24028:SF73 CADHERIN-87A PROTOCADHERIN GAMMA-B1 cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 MONDO|Ensembl=ENSMODG00000014306.4|UniProtKB=F6W4M4 F6W4M4 CDC25A PTHR10828:SF46 M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25 M-PHASE INDUCER PHOSPHATASE 1 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell cycle G2/M phase transition#GO:0044839;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;positive regulation of cell cycle#GO:0045787;regulation of reproductive process#GO:2000241;mitotic cell cycle process#GO:1903047;positive regulation of mitotic cell cycle#GO:0045931;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of meiotic cell cycle#GO:0051445;cell cycle process#GO:0022402;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;G2/M transition of mitotic cell cycle#GO:0000086;mitotic cell cycle phase transition#GO:0044772;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle phase transition#GO:1901990 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein modifying enzyme#PC00260;protein phosphatase#PC00195 p53 pathway#P00059>Cdc25C#P04624 MONDO|Ensembl=ENSMODG00000001225.3|UniProtKB=F7G7J2 F7G7J2 GADD45G PTHR10411:SF4 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GAMMA protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 regulation of intracellular signal transduction#GO:1902531;positive regulation of JNK cascade#GO:0046330;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of JNK cascade#GO:0046328;positive regulation of MAPK cascade#GO:0043410;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 p53 pathway#P00059>GADD45#G01575;p53 pathway#P00059>GADD45#P04626 MONDO|Ensembl=ENSMODG00000018284.4|UniProtKB=F6Q6C4 F6Q6C4 PNRC1 PTHR15405:SF4 PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR 1 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000003143.4|UniProtKB=F7CJQ7 F7CJQ7 TMOD1 PTHR10901:SF8 TROPOMODULIN TROPOMODULIN-1 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515 muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;multicellular organismal process#GO:0032501;muscle contraction#GO:0006936;developmental process#GO:0032502;cellular developmental process#GO:0048869;actin filament organization#GO:0007015;system process#GO:0003008;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular anatomical entity morphogenesis#GO:0032989;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646 contractile muscle fiber#GO:0043292;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000006358.4|UniProtKB=F6ZR04 F6ZR04 PALM PTHR10498:SF6 PARALEMMIN-RELATED PARALEMMIN-1 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cytoskeletal adaptor activity#GO:0008093 cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of cell projection assembly#GO:0060491;synapse organization#GO:0050808;positive regulation of cell projection organization#GO:0031346;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;cellular response to stimulus#GO:0051716;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of filopodium assembly#GO:0051489;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;regulation of cell projection organization#GO:0031344;developmental process#GO:0032502;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;developmental maturation#GO:0021700;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;positive regulation of cellular component organization#GO:0051130;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of cellular component biogenesis#GO:0044089;nervous system development#GO:0007399;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;actin-based cell projection#GO:0098858;postsynapse#GO:0098794;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;filopodium#GO:0030175;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;membraneless organelle#GO:0043228;cell junction#GO:0030054;synaptic membrane#GO:0097060;cytoskeleton#GO:0005856 MONDO|Ensembl=ENSMODG00000007597.4|UniProtKB=F7CPA1 F7CPA1 TTC9B PTHR11242:SF13 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 9B metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein modification process#GO:0036211;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604 membrane#GO:0016020;cellular anatomical structure#GO:0110165 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000018907.2|UniProtKB=F7C789 F7C789 ENPP5 PTHR10151:SF125 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 5 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000025642.3|UniProtKB=F6XW10 F6XW10 TERF1 PTHR46734:SF1 TELOMERIC REPEAT-BINDING FACTOR 1 TERF1 TELOMERIC REPEAT-BINDING FACTOR 1 double-stranded DNA binding#GO:0003690;RNA-directed DNA polymerase activity#GO:0003964;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;telomerase activity#GO:0003720;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740 telomere maintenance#GO:0000723;regulation of telomere maintenance#GO:0032204;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;RNA-templated DNA biosynthetic process#GO:0006278;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;telomere organization#GO:0032200;negative regulation of chromosome organization#GO:2001251;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;telomere maintenance via telomere lengthening#GO:0010833;telomere maintenance via telomerase#GO:0007004;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;organelle organization#GO:0006996;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleic acid biosynthetic process#GO:0141187;negative regulation of metabolic process#GO:0009892;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043 chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome, telomeric repeat region#GO:0140445;membrane-bounded organelle#GO:0043227;nuclear telomere cap complex#GO:0000783;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000018664.4|UniProtKB=F6UCG4 F6UCG4 PTHR22692:SF24 MYOSIN VII, XV MYOSIN VIIB actin binding motor protein#PC00040 MONDO|Ensembl=ENSMODG00000045791.1|UniProtKB=F6QYL7 F6QYL7 LOC100016358 PTHR23024:SF239 ARYLACETAMIDE DEACETYLASE AADACL2 FAMILY MEMBER 2 membrane#GO:0016020;cellular anatomical structure#GO:0110165 deacetylase#PC00087 MONDO|Ensembl=ENSMODG00000045954.1|UniProtKB=A0A5F8G5S5 A0A5F8G5S5 MRPL44 PTHR11207:SF5 RIBONUCLEASE III LARGE RIBOSOMAL SUBUNIT PROTEIN ML44 RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA metabolic process#GO:0016070;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;protein biosynthetic process#GO:0160307;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;primary miRNA processing#GO:0031053;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;translational elongation#GO:0006414;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;translation#GO:0006412;mitochondrial translation#GO:0032543;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904 endoribonuclease#PC00094;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000017503.3|UniProtKB=F7F195 F7F195 STS PTHR42693:SF9 ARYLSULFATASE FAMILY MEMBER STERYL-SULFATASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000006395.4|UniProtKB=F6TSX9 F6TSX9 PKN3 PTHR24356:SF318 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE N3 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074 MONDO|Ensembl=ENSMODG00000038569.1|UniProtKB=F7D8V8 F7D8V8 PTHR33426:SF30 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000014969.4|UniProtKB=A0A5F8GMU7 A0A5F8GMU7 ZC3H13 PTHR13585:SF31 CHASCON, ISOFORM D-RELATED ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 13 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 membraneless organelle#GO:0043228;transferase complex#GO:1990234;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607 MONDO|Ensembl=ENSMODG00000006774.4|UniProtKB=F7BU96 F7BU96 PTHR20875:SF2 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 calmodulin-related#PC00061 MONDO|Ensembl=ENSMODG00000020716.4|UniProtKB=F7BAD4 F7BAD4 EIF4E PTHR11960:SF14 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E translation factor activity#GO:0180051;nucleic acid binding#GO:0003676;binding#GO:0005488;translation initiation factor activity#GO:0003743;RNA binding#GO:0003723 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 CCKR signaling map#P06959>EIF4E#P07094;p38 MAPK pathway#P05918>eIF4E#P06024 MONDO|Ensembl=ENSMODG00000019745.4|UniProtKB=F6WNR7 F6WNR7 CRHBP PTHR10278:SF0 CORTICOTROPIN-RELEASING FACTOR-BINDING PROTEIN CORTICOTROPIN-RELEASING HORMONE-BINDING PROTEIN hormone binding#GO:0042562;binding#GO:0005488;peptide hormone binding#GO:0017046 negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;regulation of hormone secretion#GO:0046883;hormone-mediated signaling pathway#GO:0009755;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;regulation of transport#GO:0051049;regulation of localization#GO:0032879;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;regulation of multicellular organismal process#GO:0051239;cell communication#GO:0007154;regulation of secretion#GO:0051046;negative regulation of multicellular organismal process#GO:0051241;cellular response to stimulus#GO:0051716;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of system process#GO:0044057;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 MONDO|Ensembl=ENSMODG00000049497.1|UniProtKB=A0A5F8HAU3 A0A5F8HAU3 LOC100031124 PTHR24249:SF79 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 9 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000019721.3|UniProtKB=F6XLW6 F6XLW6 OR1K1 PTHR26451:SF965 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 1K1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000018403.2|UniProtKB=F6W3P6 F6W3P6 TPBG PTHR24364:SF17 LP06937P TROPHOBLAST GLYCOPROTEIN regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000024073.2|UniProtKB=F7CI75 F7CI75 PTHR24072:SF136 RHO FAMILY GTPASE CELL DIVISION CONTROL PROTEIN 42 HOMOLOG guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;protein binding#GO:0005515;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166 cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of filopodium assembly#GO:0051489;actin filament organization#GO:0007015;regulation of cell projection organization#GO:0031344;transport#GO:0006810;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;localization#GO:0051179;cell communication#GO:0007154;regulation of cell projection assembly#GO:0060491;supramolecular fiber organization#GO:0097435;establishment or maintenance of cell polarity#GO:0007163;actin filament-based process#GO:0030029 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208;G-protein#PC00020 Integrin signalling pathway#P00034>Cdc42#P00938;Gonadotropin-releasing hormone receptor pathway#P06664>Cdc42#P06743;CCKR signaling map#P06959>CDC42-GDP#P07044;Ras Pathway#P04393>Cdc42#P04569;Cytoskeletal regulation by Rho GTPase#P00016>Cdc42#P00515;CCKR signaling map#P06959>CDC42-GTP#P07155;T cell activation#P00053>cdc42#P01333;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Huntington disease#P00029>Rac#P00775;Axon guidance mediated by Slit/Robo#P00008>Cdc42#P00349;p38 MAPK pathway#P05918>Cdc42#P06041;Axon guidance mediated by netrin#P00009>cdc42#P00364 MONDO|Ensembl=ENSMODG00000014181.4|UniProtKB=F6U776 F6U776 CSPG5 PTHR15381:SF1 CHONDROITIN SULFATE PROTEOGLYCAN 5 -RELATED CHONDROITIN SULFATE PROTEOGLYCAN 5 cell projection morphogenesis#GO:0048858;gliogenesis#GO:0042063;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;regeneration#GO:0031099;nervous system development#GO:0007399;cellular process#GO:0009987;neuron projection development#GO:0031175;response to stress#GO:0006950;neuron development#GO:0048666;cellular response to stress#GO:0033554;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;axon development#GO:0061564;response to wounding#GO:0009611;system development#GO:0048731;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716 cell junction#GO:0030054;synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000029236.2|UniProtKB=K7E0E0 K7E0E0 ZFYVE9 PTHR46319:SF2 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 9 response to transforming growth factor beta#GO:0071559;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular localization#GO:0051641;localization#GO:0051179;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;signaling#GO:0023052;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;intracellular transport#GO:0046907;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;establishment of localization#GO:0051234;endosomal transport#GO:0016197;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;signal transduction#GO:0007165;vesicle-mediated transport#GO:0016192;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;early endosome membrane#GO:0031901;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 TGF-beta signaling pathway#P00052>SARA#P01281 MONDO|Ensembl=ENSMODG00000020392.4|UniProtKB=F7C049 F7C049 PTPRB PTHR46957:SF2 CYTOKINE RECEPTOR RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE BETA cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 blood vessel morphogenesis#GO:0048514;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;multicellular organismal process#GO:0032501;circulatory system development#GO:0072359;tube development#GO:0035295;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;system development#GO:0048731 protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Angiogenesis#P00005>VE-PTP#P00250 MONDO|Ensembl=ENSMODG00000017140.4|UniProtKB=F6TMQ0 F6TMQ0 CDKL5 PTHR24056:SF111 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 5 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000001874.4|UniProtKB=F6S6A4 F6S6A4 PRSS8 PTHR24253:SF190 TRANSMEMBRANE PROTEASE SERINE NOVEL TRYPSIN FAMILY PROTEIN serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000028381.2|UniProtKB=K7E257 K7E257 PTHR11346:SF111 GALECTIN GALECTIN-12 carbohydrate binding#GO:0030246;oligosaccharide binding#GO:0070492;binding#GO:0005488 programmed cell death#GO:0012501;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;cell death#GO:0008219;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 extracellular matrix protein#PC00102 MONDO|Ensembl=ENSMODG00000040746.1|UniProtKB=A0A5F8GK81 A0A5F8GK81 PTHR35845:SF1 SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 1 SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 1 MONDO|Ensembl=ENSMODG00000010149.4|UniProtKB=F6TB32 F6TB32 UFD1 PTHR12555:SF13 UBIQUITIN FUSION DEGRADATON PROTEIN 1 UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1 protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;binding#GO:0005488 cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538 organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 MONDO|Ensembl=ENSMODG00000010193.4|UniProtKB=F6STB3 F6STB3 PTHR18884:SF64 SEPTIN SEPTIN-2 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 cell cycle process#GO:0022402;cellular process#GO:0009987;cell division#GO:0051301;cell cycle#GO:0007049;macromolecule localization#GO:0033036;cytokinesis#GO:0000910;intracellular protein localization#GO:0008104;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640 cell cortex#GO:0005938;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000016334.4|UniProtKB=F7FKY1 F7FKY1 IFT80 PTHR24098:SF11 OUTER SEGMENT 5 INTRAFLAGELLAR TRANSPORT PROTEIN 80 HOMOLOG cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intraciliary transport particle B#GO:0030992;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000002207.5|UniProtKB=F7G3N3 F7G3N3 USP50 PTHR21646:SF11 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 50 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of innate immune response#GO:0045088;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular process#GO:0009987;regulation of protein stability#GO:0031647;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of pattern recognition receptor signaling pathway#GO:0062208;positive regulation of immune system process#GO:0002684;regulation of canonical Wnt signaling pathway#GO:0060828;organelle organization#GO:0006996;intracellular signaling cassette#GO:0141124;endomembrane system organization#GO:0010256;regulation of response to external stimulus#GO:0032101;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of Wnt signaling pathway#GO:0030177;vesicle organization#GO:0016050;endosome organization#GO:0007032;positive regulation of response to external stimulus#GO:0032103;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;regulation of intracellular signal transduction#GO:1902531;regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056 cytosol#GO:0005829;midbody#GO:0030496;postsynapse#GO:0098794;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;cytoplasm#GO:0005737;postsynaptic density#GO:0014069;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000025582.3|UniProtKB=F6U2I7 F6U2I7 PTHR11738:SF199 MHC CLASS I NK CELL RECEPTOR IG-LIKE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 MONDO|Ensembl=ENSMODG00000001777.4|UniProtKB=F6WJ99 F6WJ99 ANKRA2 PTHR24124:SF3 ANKYRIN REPEAT FAMILY A ANKYRIN REPEAT FAMILY A PROTEIN 2 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000029440.2|UniProtKB=K7E1E6 K7E1E6 PTHR22802:SF245 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER G binding#GO:0005488;signaling receptor activity#GO:0038023;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000019400.4|UniProtKB=H9H7C6 H9H7C6 MYO1A PTHR13140:SF291 MYOSIN UNCONVENTIONAL MYOSIN-IA cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543 cellular process#GO:0009987;actin filament-based movement#GO:0030048;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;transport#GO:0006810;actin filament organization#GO:0007015;system process#GO:0003008;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization#GO:0016043;sensory perception of sound#GO:0007605;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;nervous system process#GO:0050877;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;brush border#GO:0005903;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 MONDO|Ensembl=ENSMODG00000036405.1|UniProtKB=A0A5F8GI79 A0A5F8GI79 PTHR15001:SF3 BETA-DEFENSIN 123-RELATED BETA-DEFENSIN 123 defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;immune response#GO:0006955;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;cell killing#GO:0001906;immune system process#GO:0002376 defense/immunity protein#PC00090;antimicrobial response protein#PC00051 MONDO|Ensembl=ENSMODG00000041603.1|UniProtKB=A0A5F8G6U6 A0A5F8G6U6 PTHR15527:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM6 HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM6 HOMOLOG mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;mitochondrial outer membrane translocase complex#GO:0005742;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741 primary active transporter#PC00068;transporter#PC00227 MONDO|Ensembl=ENSMODG00000008641.4|UniProtKB=F6PGG8 F6PGG8 ALDH1A2 PTHR11699:SF102 ALDEHYDE DEHYDROGENASE-RELATED RETINAL DEHYDROGENASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;diterpenoid biosynthetic process#GO:0016102;metabolic process#GO:0008152;diterpenoid metabolic process#GO:0016101;monocarboxylic acid biosynthetic process#GO:0072330;retinoid metabolic process#GO:0001523;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;aldehyde catabolic process#GO:0046185;biological regulation#GO:0065007;biosynthetic process#GO:0009058;terpenoid biosynthetic process#GO:0016114;lipid biosynthetic process#GO:0008610;hormone metabolic process#GO:0042445;isoprenoid biosynthetic process#GO:0008299;terpenoid metabolic process#GO:0006721;oxoacid metabolic process#GO:0043436;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;regulation of hormone levels#GO:0010817;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 MONDO|Ensembl=ENSMODG00000016599.5|UniProtKB=H9H707 H9H707 MEI1 PTHR12044:SF10 BCL2 INTERACTING MEDIATOR OF CELL DEATH MEIOSIS INHIBITOR PROTEIN 1 cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;reproductive process#GO:0022414;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;meiotic nuclear division#GO:0140013 MONDO|Ensembl=ENSMODG00000045257.1|UniProtKB=A0A5F8GL84 A0A5F8GL84 LOC100018929 PTHR48002:SF105 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C12 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004791.4|UniProtKB=F6VMI0 F6VMI0 MXD3 PTHR11969:SF6 MAX DIMERIZATION, MAD MAX DIMERIZATION PROTEIN 3 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000004450.4|UniProtKB=F6RS43 F6RS43 BMERB1 PTHR22704:SF1 BMERB DOMAIN-CONTAINING PROTEIN 1-RELATED BMERB DOMAIN-CONTAINING PROTEIN 1 negative regulation of cellular process#GO:0048523;regulation of microtubule polymerization or depolymerization#GO:0031110;regulation of protein depolymerization#GO:1901879;regulation of protein-containing complex disassembly#GO:0043244;negative regulation of protein depolymerization#GO:1901880;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;regulation of microtubule-based process#GO:0032886;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000014545.4|UniProtKB=A0A5F8GQR3 A0A5F8GQR3 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000019360.4|UniProtKB=F6X8Z3 F6X8Z3 WDR73 PTHR46947:SF1 WD REPEAT-CONTAINING PROTEIN 73 INTEGRATOR COMPLEX ASSEMBLY FACTOR WDR73 supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cytoplasmic microtubule organization#GO:0031122;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;cytosol#GO:0005829;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000027554.1|UniProtKB=K7E323 K7E323 PTHR24377:SF710 IP01015P-RELATED ZINC FINGER PROTEIN 181-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000004207.4|UniProtKB=F6XR83 F6XR83 CYSLTR1 PTHR24230:SF12 G-PROTEIN COUPLED RECEPTOR CYSTEINYL LEUKOTRIENE RECEPTOR 1 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000534.4|UniProtKB=A0A5F8G788 A0A5F8G788 MAFB PTHR10129:SF10 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFB nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of multicellular organismal process#GO:0051239;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell development#GO:0060284;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;regulation of developmental process#GO:0050793;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of hemopoiesis#GO:1903706;regulation of myeloid cell differentiation#GO:0045637 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 MONDO|Ensembl=ENSMODG00000006013.4|UniProtKB=F7AJ61 F7AJ61 LOC100015945 PTHR11771:SF216 LIPOXYGENASE ARACHIDONATE 12-LIPOXYGENASE, 12S-TYPE-LIKE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;arachidonate metabolic process#GO:0019369;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;icosanoid metabolic process#GO:0006690 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829 oxygenase#PC00177;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000037247.1|UniProtKB=A0A5F8GVG0 A0A5F8GVG0 PTHR11630:SF66 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM4 DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259;mitotic DNA replication#GO:1902969;nuclear DNA replication#GO:0033260;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA replication initiation#GO:0006270;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;mitotic cell cycle process#GO:1903047;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;MCM complex#GO:0042555;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000042912.1|UniProtKB=K7E628 K7E628 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000018694.3|UniProtKB=F7FQP8 F7FQP8 PTHR11905:SF148 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 30 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 reproductive process#GO:0022414;reproductive structure development#GO:0048608;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;reproductive system development#GO:0061458;system development#GO:0048731;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;proteolysis#GO:0006508;gonad development#GO:0008406;multicellular organismal process#GO:0032501;cellular process#GO:0009987;sex differentiation#GO:0007548;male gonad development#GO:0008584;animal organ development#GO:0048513;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;male sex differentiation#GO:0046661;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;development of primary male sexual characteristics#GO:0046546;metabolic process#GO:0008152 external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane region#GO:0098590 metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000020699.4|UniProtKB=F7D1G1 F7D1G1 ARL9 PTHR46724:SF2 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 9-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 9 MONDO|Ensembl=ENSMODG00000018811.4|UniProtKB=A0A5F8H101 A0A5F8H101 CTSK PTHR12411:SF1048 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN K cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 MONDO|Ensembl=ENSMODG00000001178.4|UniProtKB=A0A5F8GVZ5 A0A5F8GVZ5 SAFB2 PTHR15683:SF6 SCAFFOLD ATTACHMENT FACTOR B-RELATED SCAFFOLD ATTACHMENT FACTOR B-RELATED cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000029656.2|UniProtKB=K7E316 K7E316 CASP18 PTHR10454:SF241 CASPASE CASPASE-8 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 positive regulation of neuron apoptotic process#GO:0043525;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;programmed cell death#GO:0012501;regulation of neuron apoptotic process#GO:0043523;regulation of programmed cell death#GO:0043067;cell death#GO:0008219;apoptotic process#GO:0006915;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;biological regulation#GO:0065007 cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protease#PC00190 MONDO|Ensembl=ENSMODG00000013575.4|UniProtKB=F7BHX0 F7BHX0 F2R PTHR24232:SF20 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 1 molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 response to stimulus#GO:0050896;regulation of blood coagulation#GO:0030193;regulation of cellular process#GO:0050794;regulation of body fluid levels#GO:0050878;signaling#GO:0023052;regulation of wound healing#GO:0061041;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;cell communication#GO:0007154;regulation of biological quality#GO:0065008;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of coagulation#GO:0050820;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of response to stimulus#GO:0048584;regulation of coagulation#GO:0050818;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of response to wounding#GO:1903034;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of hemostasis#GO:1900046;cellular process#GO:0009987;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Angiogenesis#P00005>PAR#P00192;Blood coagulation#P00011>PAR-1#P00404 MONDO|Ensembl=ENSMODG00000051193.1|UniProtKB=A0A5F8GC46 A0A5F8GC46 PTHR46751:SF6 EPPIN BPTI_KUNITZ INHIBITOR DOMAIN-CONTAINING PROTEIN regulation of microtubule-based process#GO:0032886;negative regulation of cellular process#GO:0048523;regulation of cell motility#GO:2000145;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;negative regulation of locomotion#GO:0040013;regulation of cellular process#GO:0050794;regulation of microtubule-based movement#GO:0060632;regulation of reproductive process#GO:2000241 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000004076.4|UniProtKB=A0A5F8HD62 A0A5F8HD62 CDK5 PTHR24056:SF594 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 5 cyclin-dependent protein serine/threonine kinase activity#GO:0004693;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;organelle localization#GO:0051640;cell death#GO:0008219;programmed cell death#GO:0012501;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;vesicle localization#GO:0051648;axon development#GO:0061564;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular localization#GO:0051641;neuron apoptotic process#GO:0051402;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;establishment of organelle localization#GO:0051656;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;apoptotic process#GO:0006915;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle transport#GO:0048489;neuron projection development#GO:0031175 serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Axon guidance mediated by semaphorins#P00007>Cdk5#P00336;Dopamine receptor mediated signaling pathway#P05912>CDK5#P05951;Nicotine pharmacodynamics pathway#P06587>CDK5#P06597;PDGF signaling pathway#P00047>GSK3#P01153;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902 MONDO|Ensembl=ENSMODG00000007582.4|UniProtKB=A0A5F8GGD0 A0A5F8GGD0 PTHR11431:SF134 FERRITIN FERRITIN HEAVY CHAIN ferrous iron binding#GO:0008198;iron ion binding#GO:0005506;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 storage protein#PC00210 MONDO|Ensembl=ENSMODG00000013816.3|UniProtKB=F6SXB4 F6SXB4 PTHR10876:SF7 ZINC FINGER PROTEIN ZPR1 ZINC FINGER PROTEIN ZPR1 binding#GO:0005488;protein binding#GO:0005515 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457 supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000008278.4|UniProtKB=F6YIY3 F6YIY3 LATS2 PTHR24356:SF149 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE LATS2 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;cell cycle G1/S phase transition#GO:0044843;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;hippo signaling#GO:0035329;regulation of apoptotic process#GO:0042981;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047;positive regulation of apoptotic process#GO:0043065;regulation of biological process#GO:0050789;regulation of growth#GO:0040008;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;regulation of programmed cell death#GO:0043067;cell cycle#GO:0007049;signaling#GO:0023052;regulation of developmental process#GO:0050793;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;cell cycle phase transition#GO:0044770;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;mitotic cell cycle phase transition#GO:0044772;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856 non-receptor serine/threonine protein kinase#PC00167 MONDO|Ensembl=ENSMODG00000014788.4|UniProtKB=A0A5F8G4L2 A0A5F8G4L2 KAT2A PTHR45750:SF1 GH11602P HISTONE ACETYLTRANSFERASE KAT2A catalytic activity#GO:0003824;transferase activity#GO:0016740;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402 positive regulation of RNA metabolic process#GO:0051254;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000015270.4|UniProtKB=F6TMK1 F6TMK1 ENTPD3 PTHR11782:SF38 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 3 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110;ribonucleoside triphosphate phosphatase activity#GO:0017111 organophosphate catabolic process#GO:0046434;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleoside diphosphate metabolic process#GO:0009132;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 phosphatase#PC00181;nucleotide phosphatase#PC00173;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000029734.2|UniProtKB=K7E194 K7E194 PTHR10290:SF1 DNA TOPOISOMERASE I DNA TOPOISOMERASE I, MITOCHONDRIAL catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543 nucleobase-containing compound metabolic process#GO:0006139;DNA replication#GO:0006260;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;organelle organization#GO:0006996;cell cycle#GO:0007049;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome segregation#GO:0007059;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;mitochondrial nucleoid#GO:0042645;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoid#GO:0009295;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 DNA topoisomerase#PC00017;DNA metabolism protein#PC00009 DNA replication#P00017>DNA Topisomerase#P00536 MONDO|Ensembl=ENSMODG00000014020.2|UniProtKB=F6V9I7 F6V9I7 PTHR14526:SF2 AURORA KINASE A AND NINEIN-INTERACTING PROTEIN AURORA KINASE A- AND NINEIN-INTERACTING PROTEIN molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 response to stimulus#GO:0050896;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;cytoskeleton organization#GO:0007010;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;microtubule-based process#GO:0007017;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310 chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 MONDO|Ensembl=ENSMODG00000013772.4|UniProtKB=F6TVT6 F6TVT6 NTF4 PTHR11589:SF8 NERVE GROWTH FACTOR NGF -RELATED NEUROTROPHIN-4 signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cellular response to stimulus#GO:0051716;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of apoptotic process#GO:0043066;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;cellular response to growth factor stimulus#GO:0071363;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;negative regulation of neuron apoptotic process#GO:0043524;regulation of neuron apoptotic process#GO:0043523;neuron projection development#GO:0031175;nervous system development#GO:0007399;regulation of trans-synaptic signaling#GO:0099177;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular response to nerve growth factor stimulus#GO:1990090;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;exocytic vesicle#GO:0070382;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;presynapse#GO:0098793;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;cell junction#GO:0030054 neurotrophic factor#PC00163;growth factor#PC00112 MONDO|Ensembl=ENSMODG00000048943.1|UniProtKB=A0A5F8HFF9 A0A5F8HFF9 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune effector process#GO:0002252;immune system process#GO:0002376 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000039057.1|UniProtKB=A0A5F8GDI9 A0A5F8GDI9 ITGAD PTHR23220:SF118 INTEGRIN ALPHA INTEGRIN SUBUNIT ALPHA D molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986 cell adhesion molecule#PC00069;integrin#PC00126 MONDO|Ensembl=ENSMODG00000040154.1|UniProtKB=A0A5F8G4S1 A0A5F8G4S1 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000009603.5|UniProtKB=F7A8M4 F7A8M4 RELA PTHR24169:SF1 NUCLEAR FACTOR NF-KAPPA-B PROTEIN TRANSCRIPTION FACTOR P65 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;response to bacterium#GO:0009617;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;response to external biotic stimulus#GO:0043207;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;cellular response to molecule of bacterial origin#GO:0071219;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;defense response#GO:0006952;response to external stimulus#GO:0009605;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;canonical NF-kappaB signal transduction#GO:0007249;response to other organism#GO:0051707;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;response to peptide#GO:1901652;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;response to lipopolysaccharide#GO:0032496;positive regulation of transcription by RNA polymerase II#GO:0045944;defense response to other organism#GO:0098542;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;intracellular signaling cassette#GO:0141124;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;non-canonical NF-kappaB signal transduction#GO:0038061;positive regulation of biological process#GO:0048518 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252;DNA-binding transcription factor#PC00218 Toll receptor signaling pathway#P00054>NFkappaB#P01354;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Apoptosis signaling pathway#P00006>NFkappaB#P00297;Gonadotropin-releasing hormone receptor pathway#P06664>p65#P06702 MONDO|Ensembl=ENSMODG00000027919.2|UniProtKB=K7E3I9 K7E3I9 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000024315.2|UniProtKB=F7E178 F7E178 PTHR48018:SF147 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M3 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000002564.4|UniProtKB=F7GFA6 F7GFA6 CHPT1 PTHR10414:SF32 ETHANOLAMINEPHOSPHOTRANSFERASE CHOLINEPHOSPHOTRANSFERASE 1 transferase#PC00220 MONDO|Ensembl=ENSMODG00000004236.4|UniProtKB=A0A5F8HFZ1 A0A5F8HFZ1 IFT74 PTHR31432:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;intraciliary transport involved in cilium assembly#GO:0035735;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073 intraciliary transport particle#GO:0030990;intraciliary transport particle B#GO:0030992;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 MONDO|Ensembl=ENSMODG00000013404.4|UniProtKB=F7G6M8 F7G6M8 SCN10A PTHR10037:SF208 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 10 SUBUNIT ALPHA monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;metal ion transmembrane transporter activity#GO:0046873;voltage-gated sodium channel activity#GO:0005248;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;passive transmembrane transporter activity#GO:0022803 establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;system process#GO:0003008;regulation of system process#GO:0044057;transport#GO:0006810;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;regulation of multicellular organismal process#GO:0051239;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;sensory perception#GO:0007600;nervous system process#GO:0050877;regulation of cellular process#GO:0050794;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;regulation of heart contraction#GO:0008016;sensory perception of pain#GO:0019233;regulation of biological process#GO:0050789;action potential#GO:0001508;sodium ion transport#GO:0006814 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;transporter complex#GO:1990351;cation channel complex#GO:0034703;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;axon#GO:0030424 voltage-gated ion channel#PC00241 MONDO|Ensembl=ENSMODG00000011762.3|UniProtKB=F7CWF9 F7CWF9 PTHR35252:SF1 RETINITIS PIGMENTOSA 9 PROTEIN RETINITIS PIGMENTOSA 9 PROTEIN MONDO|Ensembl=ENSMODG00000001509.4|UniProtKB=F7F4F3 F7F4F3 PTHR15296:SF0 MEMBRANE-ASSOCIATED PROTEIN MAP17 PDZK1-INTERACTING PROTEIN 1 MONDO|Ensembl=ENSMODG00000023128.2|UniProtKB=F7EW24 F7EW24 FBXO48 PTHR12874:SF9 F-BOX ONLY PROTEIN 48-RELATED F-BOX ONLY PROTEIN 48 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151 MONDO|Ensembl=ENSMODG00000041819.1|UniProtKB=A0A5F8HAZ3 A0A5F8HAZ3 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000010885.3|UniProtKB=A0A5F8GPU7 A0A5F8GPU7 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000041411.1|UniProtKB=A0A5F8GUL1 A0A5F8GUL1 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000023370.1|UniProtKB=F6X363 F6X363 RNF183 PTHR22791:SF7 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF183 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;regulation of programmed cell death#GO:0043067;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;protein modification by small protein conjugation or removal#GO:0070647;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of cellular response to stress#GO:0080135;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of response to stress#GO:0080134;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of intrinsic apoptotic signaling pathway#GO:2001242;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;response to endoplasmic reticulum stress#GO:0034976;regulation of apoptotic signaling pathway#GO:2001233;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000001567.3|UniProtKB=F7BX40 F7BX40 LOC100012393 PTHR26453:SF116 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2F1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000011827.4|UniProtKB=F7GM18 F7GM18 TEX264 PTHR15949:SF3 TESTIS-EXPRESSED PROTEIN 264 TESTIS-EXPRESSED PROTEIN 264 process utilizing autophagic mechanism#GO:0061919;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macroautophagy#GO:0016236;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;autophagy#GO:0006914;reticulophagy#GO:0061709;response to stress#GO:0006950 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;replication fork#GO:0005657;chromosome#GO:0005694;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;autophagosome#GO:0005776;intracellular membraneless organelle#GO:0043232;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;nucleus#GO:0005634;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;vacuolar membrane#GO:0005774;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 MONDO|Ensembl=ENSMODG00000004954.4|UniProtKB=F7A6D8 F7A6D8 EMC2 PTHR12760:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN ER MEMBRANE PROTEIN COMPLEX SUBUNIT 2 membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 cellular component organization#GO:0016043;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104 membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;EMC complex#GO:0072546;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000015328.3|UniProtKB=F6XFK3 F6XFK3 CNPPD1 PTHR15615:SF127 FAMILY NOT NAMED PROTEIN CNPPD1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 MONDO|Ensembl=ENSMODG00000011587.4|UniProtKB=A0A5F8GYP7 A0A5F8GYP7 NFIX PTHR11492:SF3 NUCLEAR FACTOR I NUCLEAR FACTOR 1 X-TYPE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000003241.4|UniProtKB=F6THT5 F6THT5 ATP5F1A PTHR48082:SF2 ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL ATP SYNTHASE F(1) COMPLEX SUBUNIT ALPHA, MITOCHONDRIAL proton channel activity#GO:0015252;nucleotide binding#GO:0000166;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;purine ribonucleotide binding#GO:0032555;monoatomic ion channel activity#GO:0005216;heterocyclic compound binding#GO:1901363;monoatomic ion transmembrane transporter activity#GO:0015075;ribonucleotide binding#GO:0032553;ligase activity#GO:0016874;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265 carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate biosynthetic process#GO:1901293;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;ribose phosphate biosynthetic process#GO:0046390;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117 proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex#GO:0098803;membrane#GO:0016020;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;proton-transporting ATP synthase complex#GO:0045259 primary active transporter#PC00068;ATP synthase#PC00002 ATP synthesis#P02721>F1 alpha#P02791 MONDO|Ensembl=ENSMODG00000008872.2|UniProtKB=F7CAY2 F7CAY2 PTHR31022:SF4 CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of spindle organization#GO:0090224;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of mitotic spindle organization#GO:0060236;regulation of spindle assembly#GO:0090169;regulation of microtubule-based process#GO:0032886;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;regulation of mitotic spindle assembly#GO:1901673 membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929;intracellular organelle#GO:0043229;axon#GO:0030424;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 MONDO|Ensembl=ENSMODG00000019215.4|UniProtKB=A0A5F8HD81 A0A5F8HD81 NF1 PTHR10194:SF142 RAS GTPASE-ACTIVATING PROTEINS NEUROFIBROMIN GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 MONDO|Ensembl=ENSMODG00000024692.1|UniProtKB=F7FCW5 F7FCW5 RMI1 PTHR14790:SF15 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 RMI1 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;reproductive process#GO:0022414;homologous recombination#GO:0035825;sexual reproduction#GO:0019953;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;resolution of meiotic recombination intermediates#GO:0000712;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA repair#GO:0006281;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;response to stimulus#GO:0050896;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;DNA helicase complex#GO:0033202;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 MONDO|Ensembl=ENSMODG00000005157.4|UniProtKB=F7EPU9 F7EPU9 DAZAP1 PTHR48027:SF23 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED DAZ-ASSOCIATED PROTEIN 1 RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 positive regulation of biosynthetic process#GO:0009891;multicellular organismal reproductive process#GO:0048609;regulation of RNA metabolic process#GO:0051252;sexual reproduction#GO:0019953;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;developmental process#GO:0032502;spermatogenesis#GO:0007283;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;male gamete generation#GO:0048232;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;gamete generation#GO:0007276;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 MONDO|Ensembl=ENSMODG00000014591.4|UniProtKB=A0A5F8HH04 A0A5F8HH04 PTHR24377:SF1051 IP01015P-RELATED ZINC FINGER PROTEIN 300 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000024855.2|UniProtKB=F7AXC0 F7AXC0 LOC100026176 PTHR11071:SF490 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000016078.4|UniProtKB=A0A5F8GY66 A0A5F8GY66 CDC42 PTHR24072:SF337 RHO FAMILY GTPASE CELL DIVISION CONTROL PROTEIN 42 HOMOLOG ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;localization#GO:0051179;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;signaling#GO:0023052;response to stimulus#GO:0050896;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;establishment of cell polarity#GO:0030010;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein#PC00020;small GTPase#PC00208 Axon guidance mediated by Slit/Robo#P00008>Cdc42#P00349;p38 MAPK pathway#P05918>Cdc42#P06041;Axon guidance mediated by netrin#P00009>cdc42#P00364;T cell activation#P00053>cdc42#P01333;Cytoskeletal regulation by Rho GTPase#P00016>Cdc42#P00515;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Huntington disease#P00029>Rac#P00775;Ras Pathway#P04393>Cdc42#P04569;Integrin signalling pathway#P00034>Cdc42#P00938 MONDO|Ensembl=ENSMODG00000025640.3|UniProtKB=F6XW47 F6XW47 PTHR10658:SF27 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PHOSPHATIDYLINOSITOL TRANSFER PROTEIN BETA ISOFORM lipid transfer activity#GO:0120013;lipid binding#GO:0008289;binding#GO:0005488;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303;cation binding#GO:0043169;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylcholine intramembrane carrier activity#GO:0008525;ion binding#GO:0043167;lipid carrier activity#GO:0005319;phosphatidylcholine binding#GO:0031210;phosphatidylinositol transfer activity#GO:0008526;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transporter#PC00227 MONDO|Ensembl=ENSMODG00000013532.4|UniProtKB=F7D6J6 F7D6J6 MPZL2 PTHR13869:SF21 MYELIN P0 RELATED MYELIN PROTEIN ZERO-LIKE PROTEIN 2 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 myelin protein#PC00161 MONDO|Ensembl=ENSMODG00000013769.3|UniProtKB=F6TWC3 F6TWC3 PTHR45740:SF8 POLY [ADP-RIBOSE] POLYMERASE ZINC FINGER CCCH-TYPE ANTIVIRAL PROTEIN 1 glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;molecular adaptor activity#GO:0060090;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein-RNA adaptor activity#GO:0140517;protein-macromolecule adaptor activity#GO:0030674;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763 response to chemical#GO:0042221;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;positive regulation of response to external stimulus#GO:0032103;regulation of mRNA catabolic process#GO:0061013;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of innate immune response#GO:0045089;cellular response to nitrogen compound#GO:1901699;post-translational protein modification#GO:0043687;response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;regulation of response to stress#GO:0080134;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;positive regulation of mRNA catabolic process#GO:0061014;positive regulation of cell communication#GO:0010647;regulation of response to biotic stimulus#GO:0002831;response to external biotic stimulus#GO:0043207;protein metabolic process#GO:0019538;response to nitrogen compound#GO:1901698;positive regulation of pattern recognition receptor signaling pathway#GO:0062208;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;positive regulation of response to biotic stimulus#GO:0002833;primary metabolic process#GO:0044238;protein modification process#GO:0036211;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of cell communication#GO:0010646;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;response to virus#GO:0009615;macromolecule modification#GO:0043412;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 MONDO|Ensembl=ENSMODG00000015905.3|UniProtKB=A0A5F8HC09 A0A5F8HC09 SENP5 PTHR12606:SF10 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 5 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 protease#PC00190 MONDO|Ensembl=ENSMODG00000004456.3|UniProtKB=F6R6U9 F6R6U9 CCDC90B PTHR14360:SF14 PROTEIN FMP32, MITOCHONDRIAL COILED-COIL DOMAIN-CONTAINING PROTEIN 90B, MITOCHONDRIAL intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000045632.1|UniProtKB=A0A5F8GU84 A0A5F8GU84 monDomV1R1205 PTHR24062:SF209 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR binding#GO:0005488 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000042368.1|UniProtKB=A0A5F8GP13 A0A5F8GP13 PTHR10177:SF444 CYCLINS CYCLIN-A2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772 membraneless organelle#GO:0043228;protein kinase complex#GO:1902911;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin A#P04666 MONDO|Ensembl=ENSMODG00000001462.3|UniProtKB=F7APR5 F7APR5 DRD5 PTHR24248:SF136 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(1B) DOPAMINE RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960 response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;G protein-coupled dopamine receptor signaling pathway#GO:0007212;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;adrenergic receptor signaling pathway#GO:0071875;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D1/D5#P05948 MONDO|Ensembl=ENSMODG00000024176.2|UniProtKB=F6WGQ6 F6WGQ6 CNTD1 PTHR21615:SF2 CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN 1 CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN 1 Cell cycle#P00013>Proteasome#P00480 MONDO|Ensembl=ENSMODG00000048164.1|UniProtKB=A0A5F8H4L8 A0A5F8H4L8 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000014483.4|UniProtKB=F6ZG26 F6ZG26 GPR137C PTHR15146:SF1 INTEGRAL MEMBRANE PROTEIN GPR137 INTEGRAL MEMBRANE PROTEIN GPR137C regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of TORC1 signaling#GO:1903432;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of TORC1 signaling#GO:1904263;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852 MONDO|Ensembl=ENSMODG00000001356.4|UniProtKB=F7FW06 F7FW06 DNAH11 PTHR10676:SF263 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 11 cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;protein binding#GO:0005515;microtubule motor activity#GO:0003777;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657 microtubule-based movement#GO:0007018;cell motility#GO:0048870;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;microtubule-based process#GO:0007017;cilium-dependent cell motility#GO:0060285;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;9+2 motile cilium#GO:0097729;cilium#GO:0005929;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;dynein complex#GO:0030286;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 MONDO|Ensembl=ENSMODG00000043545.1|UniProtKB=A0A5F8GZV1 A0A5F8GZV1 LOC100020901 PTHR24390:SF250 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 763 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008914.3|UniProtKB=F7GL86 F7GL86 OTUD1 PTHR12419:SF101 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234 cysteine protease#PC00081 MONDO|Ensembl=ENSMODG00000013220.4|UniProtKB=F7EDF9 F7EDF9 OLFM1 PTHR23192:SF34 OLFACTOMEDIN-RELATED NOELIN cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000015180.4|UniProtKB=F7BWE5 F7BWE5 DES PTHR45652:SF2 GLIAL FIBRILLARY ACIDIC PROTEIN DESMIN structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;muscle organ development#GO:0007517;developmental process#GO:0032502;intermediate filament cytoskeleton organization#GO:0045104;muscle structure development#GO:0061061;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;intermediate filament organization#GO:0045109 cellular anatomical structure#GO:0110165;organelle#GO:0043226;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;Z disc#GO:0030018;cell periphery#GO:0071944;contractile muscle fiber#GO:0043292;cell-cell junction#GO:0005911;membrane#GO:0016020;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell junction#GO:0030054;sarcolemma#GO:0042383;sarcomere#GO:0030017;I band#GO:0031674;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;intermediate filament#PC00129 MONDO|Ensembl=ENSMODG00000005243.4|UniProtKB=F6YN06 F6YN06 WDR3 PTHR19853:SF0 WD REPEAT CONTAINING PROTEIN 3 WDR3 WD REPEAT-CONTAINING PROTEIN 3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;small-subunit processome#GO:0032040;90S preribosome#GO:0030686;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 MONDO|Ensembl=ENSMODG00000014975.3|UniProtKB=A0A5F8H495 A0A5F8H495 CPB2 PTHR11705:SF17 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE B2 catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;carboxypeptidase activity#GO:0004180 regulation of multicellular organismal process#GO:0051239;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;fibrinolysis#GO:0042730;regulation of coagulation#GO:0050818;regulation of hemostasis#GO:1900046;cellular process#GO:0009987;negative regulation of wound healing#GO:0061045;regulation of response to wounding#GO:1903034;negative regulation of response to wounding#GO:1903035;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;negative regulation of blood coagulation#GO:0030195;regulation of response to stress#GO:0080134;metabolic process#GO:0008152;regulation of wound healing#GO:0061041;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;negative regulation of coagulation#GO:0050819;negative regulation of hemostasis#GO:1900047;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Plasminogen activating cascade#P00050>TAFI#P01247 MONDO|Ensembl=ENSMODG00000005689.4|UniProtKB=F6UKY4 F6UKY4 PHF10 PTHR10615:SF174 HISTONE ACETYLTRANSFERASE PHD FINGER PROTEIN 10 protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;binding#GO:0005488;acetyltransferase activity#GO:0016407;transcription regulator activity#GO:0140110;protein N-acetyltransferase activity#GO:0034212;transferase activity#GO:0016740;histone acetyltransferase activity#GO:0004402;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;N-acetyltransferase activity#GO:0008080;chromatin binding#GO:0003682;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000001783.4|UniProtKB=F6WIY1 F6WIY1 EML6 PTHR13720:SF52 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 6 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000014107.3|UniProtKB=F6QIU8 F6QIU8 NDUFA4 PTHR14256:SF4 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT CYTOCHROME C OXIDASE SUBUNIT FA4 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000003588.4|UniProtKB=F7FPX4 F7FPX4 DBT PTHR43178:SF18 LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED CHAIN ALPHA_KETOACID DEHYDROGENASE COMPLEX LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transferase#PC00220;acetyltransferase#PC00038 MONDO|Ensembl=ENSMODG00000002196.4|UniProtKB=F7GDX3 F7GDX3 TRPM7 PTHR13800:SF8 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 7 calcium ion transmembrane transporter activity#GO:0015085;protein kinase activity#GO:0004672;monoatomic cation transmembrane transporter activity#GO:0008324;phosphotransferase activity, alcohol group as acceptor#GO:0016773;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;kinase activity#GO:0016301;transferase activity#GO:0016740;channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;catalytic activity, acting on a protein#GO:0140096;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;transferase activity, transferring phosphorus-containing groups#GO:0016772;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824 transport#GO:0006810;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 MONDO|Ensembl=ENSMODG00000040120.1|UniProtKB=A0A5F8GHI1 A0A5F8GHI1 PTHR38324:SF1 TRANSMEMBRANE PROTEIN 158 TRANSMEMBRANE PROTEIN 158 peptide binding#GO:0042277;binding#GO:0005488 MONDO|Ensembl=ENSMODG00000048002.1|UniProtKB=A0A5F8GX43 A0A5F8GX43 PTHR23226:SF366 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ZFP2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000045646.1|UniProtKB=A0A5F8H9S4 A0A5F8H9S4 METTL26 PTHR20974:SF2 UPF0585 PROTEIN CG18661 METHYLTRANSFERASE-LIKE 26 MONDO|Ensembl=ENSMODG00000016549.4|UniProtKB=A0A5F8H466 A0A5F8H466 VAPB PTHR10809:SF12 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN B_C protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum membrane organization#GO:0090158;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;cellular component organization#GO:0016043 organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 MONDO|Ensembl=ENSMODG00000027649.2|UniProtKB=K7E111 K7E111 PTHR24377:SF975 IP01015P-RELATED ZINC FINGER PROTEIN 883-LIKE RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000002081.4|UniProtKB=F6V001 F6V001 ADCY2 PTHR45627:SF6 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 2 phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824;adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829 ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;signal transduction#GO:0007165;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 adenylate cyclase#PC00043 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AC#P00841;Beta2 adrenergic receptor signaling pathway#P04378>AC#P04446;Opioid proopiomelanocortin pathway#P05917>AC#P06011;Enkephalin release#P05913>AC#P05978;Nicotine pharmacodynamics pathway#P06587>ADCY2#P06606;5HT1 type receptor mediated signaling pathway#P04373>AC#P04406;Beta1 adrenergic receptor signaling pathway#P04377>AC#P04439;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Histamine H2 receptor mediated signaling pathway#P04386>AC#P04492;5HT4 type receptor mediated signaling pathway#P04376>AC#P04429;Opioid proenkephalin pathway#P05915>AC#P05993;Beta3 adrenergic receptor signaling pathway#P04379>AC#P04450;Opioid prodynorphin pathway#P05916>AC#P06001;Dopamine receptor mediated signaling pathway#P05912>AC#P05947;GABA-B receptor II signaling#P05731>AC#P05760 MONDO|Ensembl=ENSMODG00000016554.3|UniProtKB=F7DNS7 F7DNS7 PTHR15260:SF1 SARCOSPAN SARCOSPAN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;sarcolemma#GO:0042383;cell periphery#GO:0071944;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000045347.1|UniProtKB=A0A5F8H932 A0A5F8H932 ZFAND5 PTHR10634:SF26 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE ZINC FINGER PROTEIN 5 MONDO|Ensembl=ENSMODG00000047821.1|UniProtKB=F7FBK3 F7FBK3 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000038639.1|UniProtKB=A0A5F8G5Y1 A0A5F8G5Y1 LOC100016960 PTHR26450:SF411 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51A7 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000021251.3|UniProtKB=F6TIU5 F6TIU5 ZIC1 PTHR19818:SF141 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000007690.5|UniProtKB=F7F9W6 F7F9W6 OSGIN2 PTHR15192:SF4 PROTEIN CBG05349 OXIDATIVE STRESS-INDUCED GROWTH INHIBITOR 2 growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of cellular component organization#GO:0051128;regulation of cell growth#GO:0001558;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cell growth#GO:0030308;negative regulation of biological process#GO:0048519;regulation of growth#GO:0040008;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523 MONDO|Ensembl=ENSMODG00000012998.3|UniProtKB=F7CRK8 F7CRK8 FAM163B PTHR31396:SF2 PROTEIN FAM163B MEMBER PROTEIN FAM163B MONDO|Ensembl=ENSMODG00000002760.3|UniProtKB=F6YH50 F6YH50 KLF9 PTHR23235:SF132 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 9 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015953.4|UniProtKB=F7FRI3 F7FRI3 ABCF1 PTHR19211:SF14 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 1 purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 translation elongation factor#PC00222 MONDO|Ensembl=ENSMODG00000019204.4|UniProtKB=F6ZIT8 F6ZIT8 SUZ12 PTHR22597:SF0 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SUZ12 binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;DNA binding#GO:0003677 regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;constitutive heterochromatin formation#GO:0140719;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;heterochromatin organization#GO:0070828;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;cellular component assembly#GO:0022607 organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000017437.4|UniProtKB=F6ZUH1 F6ZUH1 WWC3 PTHR14791:SF25 BOMB/KIRA PROTEINS PROTEIN WWC3 binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein binding#GO:0005515 cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell migration#GO:0016477;regulation of response to stimulus#GO:0048583;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of growth#GO:0040008;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of developmental process#GO:0050793;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000021045.3|UniProtKB=A0A5F8GV33 A0A5F8GV33 PTHR10210:SF123 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000000130.3|UniProtKB=F6YBC0 F6YBC0 LFNG PTHR10811:SF7 FRINGE-RELATED BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE LUNATIC FRINGE acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of Notch signaling pathway#GO:0008593;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789 glycosyltransferase#PC00111;transferase#PC00220 Notch signaling pathway#P00045>Fringe#P01107 MONDO|Ensembl=ENSMODG00000017345.4|UniProtKB=F6WFG8 F6WFG8 SLC27A3 PTHR43107:SF12 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 3 carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;monocarboxylic acid transmembrane transporter activity#GO:0008028;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;catalytic activity#GO:0003824 lipid localization#GO:0010876;oxoacid metabolic process#GO:0043436;localization#GO:0051179;fatty acid transport#GO:0015908;monocarboxylic acid transport#GO:0015718;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;lipid metabolic process#GO:0006629;import into cell#GO:0098657;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid transport#GO:0006869 mitochondrion#GO:0005739;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000012592.5|UniProtKB=F6PIK2 F6PIK2 TSC1 PTHR15154:SF2 HAMARTIN HAMARTIN regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of cell population proliferation#GO:0042127;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of TOR signaling#GO:0032006;negative regulation of cell population proliferation#GO:0008285;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>TSC1#P04495;p53 pathway by glucose deprivation#P04397>TSC1#P04645 MONDO|Ensembl=ENSMODG00000011772.4|UniProtKB=F7CW03 F7CW03 CXXC5 PTHR13419:SF2 ZINC FINGER-CONTAINING CXXC-TYPE ZINC FINGER PROTEIN 5 nucleotide binding#GO:0000166;sequence-specific DNA binding#GO:0043565;heterocyclic compound binding#GO:1901363;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;nucleic acid binding#GO:0003676;binding#GO:0005488;small molecule binding#GO:0036094 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000018701.2|UniProtKB=A0A5F8GBE2 A0A5F8GBE2 PTP4A1 PTHR23339:SF55 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE TYPE IVA 1 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145;regulation of cell migration#GO:0030334;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of cell motility#GO:2000147 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein phosphatase#PC00195;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000016095.2|UniProtKB=F7FYS7 F7FYS7 NDUFB10 PTHR13094:SF1 NADH-UBIQUINONE OXIDOREDUCTASE PDSW SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020 oxidoreductase#PC00176 MONDO|Ensembl=ENSMODG00000000755.4|UniProtKB=A0A5F8GL11 A0A5F8GL11 KDM5B PTHR10694:SF3 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 5B histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;protein demethylase activity#GO:0140457;demethylase activity#GO:0032451;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000002992.4|UniProtKB=F6Q4C9 F6Q4C9 NFATC4 PTHR12533:SF11 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;intracellular signaling cassette#GO:0141124;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;calcium-mediated signaling#GO:0019722;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;calcineurin-NFAT signaling cascade#GO:0033173;calcineurin-mediated signaling#GO:0097720;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 immunoglobulin fold transcription factor#PC00251;gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252 Wnt signaling pathway#P00057>NFAT#P01452;B cell activation#P00010>NFAT#P00367;Axon guidance mediated by netrin#P00009>NFAT#P00359;T cell activation#P00053>NFAT#P01294;Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851 MONDO|Ensembl=ENSMODG00000015154.4|UniProtKB=F7CFM6 F7CFM6 P2RX2 PTHR10125:SF4 P2X PURINOCEPTOR P2X PURINOCEPTOR 2 ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216 transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;calcium ion transmembrane transport#GO:0070588;cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 MONDO|Ensembl=ENSMODG00000044210.1|UniProtKB=A0A5F8HIZ3 A0A5F8HIZ3 PTHR48069:SF6 DIHYDROFOLATE REDUCTASE DIHYDROFOLATE REDUCTASE oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076;binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265 biosynthetic process#GO:0009058;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;tetrahydrofolate metabolic process#GO:0046653;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948 MONDO|Ensembl=ENSMODG00000044518.1|UniProtKB=A0A5F8G352 A0A5F8G352 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000003532.4|UniProtKB=F7GBS5 F7GBS5 PSME1 PTHR10660:SF5 PROTEASOME REGULATOR PA28 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;peptidase activator activity#GO:0016504;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;enzyme activator activity#GO:0008047 regulation of proteasomal protein catabolic process#GO:0061136;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of mitotic cell cycle#GO:0007346;regulation of catabolic process#GO:0009894;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;regulation of cell cycle phase transition#GO:1901987;regulation of biological process#GO:0050789;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of protein catabolic process#GO:0042176;regulation of G1/S transition of mitotic cell cycle#GO:2000045 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MONDO|Ensembl=ENSMODG00000013211.4|UniProtKB=F7EW01 F7EW01 RTRAF PTHR15924:SF9 CLE TRNA-SPLICING LIGASE COMPLEX SUBUNIT RTRAF binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 MONDO|Ensembl=ENSMODG00000025084.2|UniProtKB=F6VPP4 F6VPP4 MGAT3 PTHR12224:SF0 BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 metabolic process#GO:0008152;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040 transferase#PC00220;glycosyltransferase#PC00111 MONDO|Ensembl=ENSMODG00000051476.1|UniProtKB=A0A5F8H5U2 A0A5F8H5U2 PSME3 PTHR10660:SF8 PROTEASOME REGULATOR PA28 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 3 enzyme activator activity#GO:0008047;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;peptidase activator activity#GO:0016504;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of mitotic cell cycle#GO:0007346;regulation of proteasomal protein catabolic process#GO:0061136;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of protein catabolic process#GO:0042176;regulation of cell cycle phase transition#GO:1901987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226 Cell cycle#P00013>Proteasome#P00480 MONDO|Ensembl=ENSMODG00000018146.3|UniProtKB=A0A5F8H2Q1 A0A5F8H2Q1 PTHR34756:SF1 CELL DIVISION CYCLE-ASSOCIATED PROTEIN 3 CELL DIVISION CYCLE-ASSOCIATED PROTEIN 3 MONDO|Ensembl=ENSMODG00000000038.4|UniProtKB=A0A5F8H907 A0A5F8H907 LYPD2 PTHR16983:SF16 UPAR/LY6 DOMAIN-CONTAINING PROTEIN LY6_PLAUR DOMAIN CONTAINING 2-RELATED signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;acetylcholine receptor inhibitor activity#GO:0030550;binding#GO:0005488;acetylcholine receptor regulator activity#GO:0030548;protein binding#GO:0005515;signaling receptor inhibitor activity#GO:0030547;molecular function inhibitor activity#GO:0140678;neurotransmitter receptor regulator activity#GO:0099602 acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000015729.4|UniProtKB=F7B524 F7B524 LSM8 PTHR15588:SF9 LSM1 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U6 snRNP#GO:0005688;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532 RNA processing factor#PC00147;RNA splicing factor#PC00148 MONDO|Ensembl=ENSMODG00000027805.2|UniProtKB=K7E459 K7E459 PTHR45901:SF7 PROTEIN CBG12474 OXYGEN-REGULATED PROTEIN 1 MONDO|Ensembl=ENSMODG00000017930.2|UniProtKB=F7EJS7 F7EJS7 GJB5 PTHR11984:SF29 CONNEXIN GAP JUNCTION BETA-5 PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 cellular process#GO:0009987;regulation of biological process#GO:0050789;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 cell junction#GO:0030054;anchoring junction#GO:0070161;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 cell junction protein#PC00070;gap junction#PC00105 MONDO|Ensembl=ENSMODG00000023216.1|UniProtKB=F7EF13 F7EF13 ANKRD34A PTHR24156:SF4 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 34A MONDO|Ensembl=ENSMODG00000015222.3|UniProtKB=A0A5F8H133 A0A5F8H133 CNOT10 PTHR12979:SF5 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10 negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;negative regulation of protein metabolic process#GO:0051248;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;RNA catabolic process#GO:0006401;negative regulation of translation#GO:0017148;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892 CCR4-NOT complex#GO:0030014;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 MONDO|Ensembl=ENSMODG00000050158.1|UniProtKB=A0A5F8GXT7 A0A5F8GXT7 PTHR24381:SF479 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 432 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000008198.4|UniProtKB=F7DJ52 F7DJ52 PTHR10747:SF26 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 P53-like transcription factor#PC00253;DNA-binding transcription factor#PC00218 MONDO|Ensembl=ENSMODG00000007272.4|UniProtKB=A0A5F8GHX6 A0A5F8GHX6 RGL1 PTHR23113:SF199 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE 1 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 Ras Pathway#P04393>RalGDS#P04551 MONDO|Ensembl=ENSMODG00000012817.4|UniProtKB=F7DY31 F7DY31 REXO4 PTHR12801:SF158 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 4 hydrolase activity, acting on ester bonds#GO:0016788;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA catabolic process#GO:0006308;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 exoribonuclease#PC00099;RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000017192.4|UniProtKB=F6XXL4 F6XXL4 PTHR21685:SF1 TON-B BOX DOMAIN TAPERIN system development#GO:0048731;anatomical structure development#GO:0048856;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;embryonic organ development#GO:0048568;animal organ morphogenesis#GO:0009887;system process#GO:0003008;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;sensory organ development#GO:0007423;epidermis development#GO:0008544;plasma membrane bounded cell projection organization#GO:0120036;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;multicellular organismal process#GO:0032501;inner ear development#GO:0048839;neuron development#GO:0048666;ear development#GO:0043583;generation of neurons#GO:0048699;nervous system process#GO:0050877;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;sensory perception of sound#GO:0007605;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;sensory organ morphogenesis#GO:0090596;anatomical structure morphogenesis#GO:0009653;inner ear receptor cell stereocilium organization#GO:0060122;cellular component organization#GO:0016043;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;embryo development#GO:0009790;cellular process#GO:0009987;inner ear morphogenesis#GO:0042472;neuron projection development#GO:0031175;hair cell differentiation#GO:0035315 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;cytoskeleton#GO:0005856;stereocilium#GO:0032420;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;neuron projection#GO:0043005 MONDO|Ensembl=ENSMODG00000010739.4|UniProtKB=K7E521 K7E521 IQGAP1 PTHR14149:SF15 RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP1 actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;cytoskeletal protein binding#GO:0008092;enzyme activator activity#GO:0008047;calmodulin binding#GO:0005516;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 cytokinetic process#GO:0032506;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;signaling#GO:0023052;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;actomyosin contractile ring assembly#GO:0000915;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin filament-based process#GO:0030029;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cortical cytoskeleton organization#GO:0030865;supramolecular fiber organization#GO:0097435;enzyme-linked receptor protein signaling pathway#GO:0007167;mitotic cytokinetic process#GO:1902410;cortical actin cytoskeleton organization#GO:0030866;cell communication#GO:0007154;cell division#GO:0051301;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;mitotic cell cycle process#GO:1903047;actin filament organization#GO:0007015;ERBB signaling pathway#GO:0038127;biological regulation#GO:0065007;cell migration#GO:0016477;epidermal growth factor receptor signaling pathway#GO:0007173 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cell cortex#GO:0005938;nucleus#GO:0005634;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000016266.3|UniProtKB=F7BHC7 F7BHC7 ABCA1 PTHR19229:SF34 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA1 ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;lipid carrier activity#GO:0005319;phosphatidylcholine intramembrane carrier activity#GO:0008525;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;transport#GO:0006810;lipid localization#GO:0010876;establishment of localization#GO:0051234;localization#GO:0051179 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 MONDO|Ensembl=ENSMODG00000004993.3|UniProtKB=F7FKI0 F7FKI0 WDR54 PTHR13720:SF40 WD-40 REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 54 cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157 MONDO|Ensembl=ENSMODG00000012060.3|UniProtKB=A0A5F8GTT3 A0A5F8GTT3 PTHR47385:SF17 CALPONIN CALPONIN-3 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000017995.5|UniProtKB=F7B7V7 F7B7V7 PHC1 PTHR12247:SF20 POLYCOMB GROUP PROTEIN POLYHOMEOTIC-LIKE PROTEIN 1 chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605 protein-containing complex#GO:0032991;PcG protein complex#GO:0031519;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular membrane-bounded organelle#GO:0043231;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000039078.1|UniProtKB=F7G5H7 F7G5H7 LOC107651962 PTHR24381:SF27 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 180 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000005920.4|UniProtKB=F6WX66 F6WX66 RPS15A PTHR11758:SF16 40S RIBOSOMAL PROTEIN S15A SMALL RIBOSOMAL SUBUNIT PROTEIN US8 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 MONDO|Ensembl=ENSMODG00000013903.3|UniProtKB=F6VBT0 F6VBT0 PTHR10693:SF21 RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN 1 catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on RNA#GO:0140098;DNA helicase activity#GO:0003678;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;ATP-dependent activity, acting on DNA#GO:0008094;binding#GO:0005488;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;nucleic acid binding#GO:0003676 membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cytoplasmic stress granule assembly#GO:0034063;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840 cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytosol#GO:0005829;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000017010.4|UniProtKB=F6QF28 F6QF28 ARL6 PTHR11711:SF21 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6 nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265 organelle assembly#GO:0070925;protein transport#GO:0015031;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;transport#GO:0006810;intracellular protein transport#GO:0006886;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cell projection assembly#GO:0030031;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192 cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 G-protein#PC00020 MONDO|Ensembl=ENSMODG00000013117.3|UniProtKB=A0A5F8GZ44 A0A5F8GZ44 PTHR47247:SF1 KUNITZ-TYPE PROTEASE INHIBITOR 2 KUNITZ-TYPE PROTEASE INHIBITOR 2 enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867 anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;developmental process#GO:0032502;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;epithelium development#GO:0060429;cell differentiation#GO:0030154;tissue development#GO:0009888;cell morphogenesis#GO:0000902;epithelial cell differentiation#GO:0030855;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987 protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000001209.4|UniProtKB=A0A5F8HET6 A0A5F8HET6 UNC50 PTHR12841:SF6 PROTEIN UNC-50 HOMOLOG PROTEIN UNC-50 HOMOLOG bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000013047.4|UniProtKB=F7G158 F7G158 ADCY7 PTHR45627:SF9 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 7 lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975 nucleoside phosphate biosynthetic process#GO:1901293;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cyclic purine nucleotide metabolic process#GO:0052652;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;ribose phosphate biosynthetic process#GO:0046390;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 adenylate cyclase#PC00043 5HT1 type receptor mediated signaling pathway#P04373>AC#P04406;Beta3 adrenergic receptor signaling pathway#P04379>AC#P04450;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760;Dopamine receptor mediated signaling pathway#P05912>AC#P05947;Opioid prodynorphin pathway#P05916>AC#P06001;Beta1 adrenergic receptor signaling pathway#P04377>AC#P04439;Opioid proenkephalin pathway#P05915>AC#P05993;Beta2 adrenergic receptor signaling pathway#P04378>AC#P04446;5HT4 type receptor mediated signaling pathway#P04376>AC#P04429;Histamine H2 receptor mediated signaling pathway#P04386>AC#P04492;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Enkephalin release#P05913>AC#P05978;Opioid proopiomelanocortin pathway#P05917>AC#P06011 MONDO|Ensembl=ENSMODG00000020935.3|UniProtKB=A0A5F8GG18 A0A5F8GG18 LOC100026816 PTHR45616:SF52 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CUTICULAR HB3 structural molecule activity#GO:0005198 keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;epidermis development#GO:0008544;developmental process#GO:0032502;cellular developmental process#GO:0048869;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;cytoskeleton organization#GO:0007010;skin development#GO:0043588 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232 MONDO|Ensembl=ENSMODG00000009775.3|UniProtKB=F6TF65 F6TF65 PTHR11785:SF340 AMINO ACID TRANSPORTER AROMATIC-PREFERRING AMINO ACID TRANSPORTER carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 cellular process#GO:0009987;amino acid transport#GO:0006865;transport#GO:0006810;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 MONDO|Ensembl=ENSMODG00000008542.2|UniProtKB=F7DH23 F7DH23 RTP1 PTHR14402:SF19 RECEPTOR TRANSPORTING PROTEIN RECEPTOR-TRANSPORTING PROTEIN 1 binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 response to stimulus#GO:0050896;protein targeting#GO:0006605;cellular component organization#GO:0016043;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;localization#GO:0051179;cellular localization#GO:0051641;detection of chemical stimulus involved in sensory perception#GO:0050907;localization within membrane#GO:0051668;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;protein insertion into membrane#GO:0051205;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;membrane organization#GO:0061024;detection of stimulus#GO:0051606;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;detection of stimulus involved in sensory perception#GO:0050906;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;intracellular protein localization#GO:0008104;sensory perception of taste#GO:0050909;protein targeting to membrane#GO:0006612;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000011622.4|UniProtKB=F6UGC0 F6UGC0 GPN3 PTHR21231:SF7 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 3 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 protein-binding activity modulator#PC00095;G-protein#PC00020;small GTPase#PC00208 MONDO|Ensembl=ENSMODG00000011297.4|UniProtKB=F6WZ33 F6WZ33 GSDMD PTHR16399:SF31 GASDERMIN GASDERMIN D LIKE 1 phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylserine binding#GO:0001786;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;inflammatory response#GO:0006954;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;response to external stimulus#GO:0009605;defense response#GO:0006952 transporter#PC00227 MONDO|Ensembl=ENSMODG00000046160.1|UniProtKB=A0A5F8GG82 A0A5F8GG82 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 MONDO|Ensembl=ENSMODG00000025063.1|UniProtKB=F6SA89 F6SA89 MC4R PTHR22750:SF6 G-PROTEIN COUPLED RECEPTOR MELANOCORTIN RECEPTOR 4 peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of multicellular organismal process#GO:0051239;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000012773.2|UniProtKB=F6S1J9 F6S1J9 PTHR23427:SF13 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 4 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000015364.4|UniProtKB=F6WHM2 F6WHM2 WNT6 PTHR12027:SF72 WNT RELATED PROTEIN WNT-6 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488 developmental process#GO:0032502;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;cell fate commitment#GO:0045165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;signaling#GO:0023052 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 MONDO|Ensembl=ENSMODG00000019200.4|UniProtKB=F6ZIX7 F6ZIX7 ATAD5 PTHR23389:SF21 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 5 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000003679.3|UniProtKB=F7FAL7 F7FAL7 APLF PTHR21315:SF2 APRATAXIN AND PNK-LIKE FACTOR-RELATED APRATAXIN AND PNK-LIKE FACTOR DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;DNA endonuclease activity#GO:0004520;catalytic activity, acting on DNA#GO:0140097 macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 chromosome#GO:0005694;site of double-strand break#GO:0035861;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734 MONDO|Ensembl=ENSMODG00000021262.4|UniProtKB=F6T396 F6T396 PTHR11709:SF314 MULTI-COPPER OXIDASE CERULOPLASMIN catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 oxidase#PC00175 MONDO|Ensembl=ENSMODG00000023054.3|UniProtKB=A0A5F8GRB9 A0A5F8GRB9 PTHR24376:SF270 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 39 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 MONDO|Ensembl=ENSMODG00000015665.3|UniProtKB=F7EI58 F7EI58 CORO1A PTHR10856:SF18 CORONIN CORONIN-1A actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;cell migration#GO:0016477 supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;lamellipodium#GO:0030027;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;actin filament#GO:0005884;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 MONDO|Ensembl=ENSMODG00000018016.4|UniProtKB=F7AKH1 F7AKH1 PDSS2 PTHR12001:SF55 GERANYLGERANYL PYROPHOSPHATE SYNTHASE ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS2 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 isoprenoid metabolic process#GO:0006720;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;isoprenoid biosynthetic process#GO:0008299;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;primary metabolic process#GO:0044238;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ubiquinone biosynthetic process#GO:0006744 mitochondrion#GO:0005739;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000046391.1|UniProtKB=A0A5F8GVL5 A0A5F8GVL5 MED20 PTHR12465:SF0 UBIQUITIN SPECIFIC PROTEASE HOMOLOG 49 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 20 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000044592.1|UniProtKB=A0A5F8HF69 A0A5F8HF69 BTBD6 PTHR45774:SF5 BTB/POZ DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN 6 cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;system development#GO:0048731;neurogenesis#GO:0022008;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 MONDO|Ensembl=ENSMODG00000011688.2|UniProtKB=F7GDZ8 F7GDZ8 DNAJA4 PTHR43888:SF9 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ HOMOLOG SUBFAMILY A MEMBER 4 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671;protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;cellular response to heat#GO:0034605;response to heat#GO:0009408;protein refolding#GO:0042026;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein folding#GO:0006457;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000001426.2|UniProtKB=F6V0D3 F6V0D3 GREM1 PTHR15283:SF3 GREMLIN 1 GREMLIN-1 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine binding#GO:0019955;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000003031.4|UniProtKB=A0A5F8GN41 A0A5F8GN41 PTHR28646:SF1 TRANSMEMBRANE PROTEIN 201 TRANSMEMBRANE PROTEIN 201 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 anatomical structure morphogenesis#GO:0009653;nuclear migration#GO:0007097;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;blood vessel morphogenesis#GO:0048514;circulatory system development#GO:0072359;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;microtubule-based transport#GO:0099111;animal gross anatomical part developmental process#GO:0160108;organelle localization#GO:0051640;system development#GO:0048731;localization#GO:0051179;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;tube development#GO:0035295;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;developmental process#GO:0032502;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;transport along microtubule#GO:0010970;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane#GO:0016020;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear membrane#GO:0031965;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000019206.3|UniProtKB=F6ZIB6 F6ZIB6 UTP6 PTHR23271:SF1 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 66 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 6 HOMOLOG nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;binding#GO:0005488;RNA binding#GO:0003723;U3 snoRNA binding#GO:0034511 ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;small-subunit processome#GO:0032040;90S preribosome#GO:0030686;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000008203.4|UniProtKB=F7DJ39 F7DJ39 AGTPBP1 PTHR12756:SF24 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 1 tubulin binding#GO:0015631;metalloexopeptidase activity#GO:0008235;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;binding#GO:0005488;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;protein binding#GO:0005515;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000050148.1|UniProtKB=F6PX60 F6PX60 LOC100018877 PTHR23428:SF322 HISTONE H2B HISTONE H2B TYPE 2-E response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to other organism#GO:0051707;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;response to external stimulus#GO:0009605;defense response#GO:0006952;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 MONDO|Ensembl=ENSMODG00000027548.2|UniProtKB=K7E5K5 K7E5K5 LOC103096992 PTHR24103:SF693 E3 UBIQUITIN-PROTEIN LIGASE TRIM NUCLEAR FACTOR 7, OVARY acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000004516.4|UniProtKB=F6UR97 F6UR97 BHLHE40 PTHR10985:SF3 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 40 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;negative regulation of biological process#GO:0048519;circadian regulation of gene expression#GO:0032922;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;rhythmic process#GO:0048511;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 MONDO|Ensembl=ENSMODG00000044179.1|UniProtKB=A0A5F8GM54 A0A5F8GM54 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000019374.3|UniProtKB=A0A5F8HHQ5 A0A5F8HHQ5 LOC130455625 PTHR13420:SF7 UPF0235 PROTEIN C15ORF40 UPF0235 PROTEIN C15ORF40 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000025038.2|UniProtKB=F6WMS6 F6WMS6 PTHR16516:SF5 AGAP007109-PA ZINC FINGER PROTEIN 488 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000019115.4|UniProtKB=F7F980 F7F980 NPFFR2 PTHR24241:SF132 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE FF RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000006332.4|UniProtKB=A0A5F8GGM2 A0A5F8GGM2 RGS22 PTHR46583:SF1 REGULATOR OF G-PROTEIN SIGNALING 22 REGULATOR OF G PROTEIN SIGNALING 22 binding#GO:0005488;protein binding#GO:0005515 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 MONDO|Ensembl=ENSMODG00000012147.3|UniProtKB=K7E186 K7E186 PSMD9 PTHR12651:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;proteasome complex#GO:0000502 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 MONDO|Ensembl=ENSMODG00000003433.4|UniProtKB=F7DX38 F7DX38 FIRRM PTHR16071:SF2 CHROMOSOME 1 OPEN READING FRAME 112 FIGNL1-INTERACTING REGULATOR OF RECOMBINATION AND MITOSIS MONDO|Ensembl=ENSMODG00000002546.4|UniProtKB=F7ALW1 F7ALW1 NCK2 PTHR19969:SF12 SH2-SH3 ADAPTOR PROTEIN-RELATED CYTOPLASMIC PROTEIN NCK2 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;binding#GO:0005488;receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090 positive regulation of apoptotic process#GO:0043065;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;negative regulation of signal transduction#GO:0009968;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;regulation of cellular response to stress#GO:0080135;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of signaling#GO:0023056;negative regulation of intracellular signal transduction#GO:1902532;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;post-transcriptional regulation of gene expression#GO:0010608;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;cell migration#GO:0016477;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of translation#GO:0045727;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of apoptotic signaling pathway#GO:2001233;response to endoplasmic reticulum stress#GO:0034976;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of response to endoplasmic reticulum stress#GO:1905897;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;regulation of intrinsic apoptotic signaling pathway#GO:2001242;positive regulation of signal transduction#GO:0009967 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Nck#P01147;Angiogenesis#P00005>Nck#P00215;T cell activation#P00053>nck#P01314 MONDO|Ensembl=ENSMODG00000005381.3|UniProtKB=F7GGM2 F7GGM2 SCGB3A2 PTHR34829:SF2 SECRETOGLOBIN FAMILY 3A MEMBER 2 SECRETOGLOBIN FAMILY 3A MEMBER 2 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000009233.4|UniProtKB=A0A5F8H596 A0A5F8H596 PLXDC2 PTHR13055:SF11 TUMOR ENDOTHELIAL MARKER 7 RELATED PLEXIN DOMAIN-CONTAINING PROTEIN 2 MONDO|Ensembl=ENSMODG00000007235.2|UniProtKB=F6WC63 F6WC63 MRPS5 PTHR13718:SF61 RIBOSOMAL S SUBUNIT SMALL RIBOSOMAL SUBUNIT PROTEIN US5M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;cytosolic ribosome#GO:0022626;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000023125.1|UniProtKB=F6YY27 F6YY27 B3GNT2 PTHR11214:SF25 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 2 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;aminoglycan biosynthetic process#GO:0006023;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111;transferase#PC00220 MONDO|Ensembl=ENSMODG00000008143.4|UniProtKB=F7ELM3 F7ELM3 GOLM1 PTHR15896:SF8 GOLGI PHOSPHOPROTEIN 2/GP73-RELATED GOLGI MEMBRANE PROTEIN 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 MONDO|Ensembl=ENSMODG00000006952.4|UniProtKB=F6RFE1 F6RFE1 NCF1 PTHR15706:SF6 SH3 MULTIPLE DOMAIN NEUTROPHIL CYTOSOL FACTOR 1-RELATED enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987;superoxide metabolic process#GO:0006801 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000018722.4|UniProtKB=F7FBY8 F7FBY8 ZNF451 PTHR24408:SF61 ZINC FINGER PROTEIN E3 SUMO-PROTEIN LIGASE ZNF451 ubiquitin-like protein ligase activity#GO:0061659;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;SUMO ligase activity#GO:0061665;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;transcription corepressor activity#GO:0003714;transferase activity#GO:0016740;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;acyltransferase activity#GO:0016746;nucleic acid binding#GO:0003676;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824 protein sumoylation#GO:0016925;metabolic process#GO:0008152;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;protein modification by small protein conjugation or removal#GO:0070647;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;post-translational protein modification#GO:0043687;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of DNA-templated transcription initiation#GO:2000142 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000046357.1|UniProtKB=A0A5F8GDG6 A0A5F8GDG6 PTHR43340:SF6 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;magnesium ion binding#GO:0000287;metal ion binding#GO:0046872 metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;purine nucleobase metabolic process#GO:0006144;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase metabolic process#GO:0009112;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;IMP metabolic process#GO:0046040;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247;Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804;Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245 MONDO|Ensembl=ENSMODG00000009737.4|UniProtKB=F6XAD2 F6XAD2 PDGFRB PTHR24416:SF53 TYROSINE-PROTEIN KINASE RECEPTOR PLATELET-DERIVED GROWTH FACTOR RECEPTOR BETA protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;angiogenesis#GO:0001525;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;positive regulation of cell population proliferation#GO:0008284;blood vessel morphogenesis#GO:0048514;signaling#GO:0023052;circulatory system development#GO:0072359;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to chemical#GO:0042221;taxis#GO:0042330;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;chemotaxis#GO:0006935;cell chemotaxis#GO:0060326;system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cell motility#GO:0048870;developmental process#GO:0032502;regulation of cell migration#GO:0030334;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;biological regulation#GO:0065007;tube development#GO:0035295;regulation of locomotion#GO:0040012;cell migration#GO:0016477;multicellular organismal process#GO:0032501 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 PDGF signaling pathway#P00047>PDGF receptor B#P01156;Angiogenesis#P00005>PDGFR#P00230 MONDO|Ensembl=ENSMODG00000010500.4|UniProtKB=F6VMS7 F6VMS7 ATP7B PTHR43520:SF30 ATP7, ISOFORM B COPPER-TRANSPORTING ATPASE 2 binding#GO:0005488;transition metal ion transmembrane transporter activity#GO:0046915;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;metal ion binding#GO:0046872;monoatomic cation transmembrane transporter activity#GO:0008324;copper ion binding#GO:0005507;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;metal ion transmembrane transporter activity#GO:0046873;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;cation binding#GO:0043169;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;copper ion transmembrane transport#GO:0035434;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000004914.4|UniProtKB=F7C1K5 F7C1K5 CASQ2 PTHR10033:SF15 CALSEQUESTRIN CALSEQUESTRIN-2 calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;molecular sequestering activity#GO:0140313;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of monoatomic ion transport#GO:0043269;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of system process#GO:0044057;calcium-mediated signaling#GO:0019722;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762;regulation of muscle system process#GO:0090257;regulation of heart contraction#GO:0008016;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;regulation of muscle contraction#GO:0006937;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;sarcoplasmic reticulum#GO:0016529;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;endoplasmic reticulum#GO:0005783;I band#GO:0031674;membraneless organelle#GO:0043228;sarcomere#GO:0030017;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;sarcoplasm#GO:0016528;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 calcium-binding protein#PC00060 MONDO|Ensembl=ENSMODG00000010093.3|UniProtKB=F6XLQ9 F6XLQ9 THAP1 PTHR46600:SF14 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 MONDO|Ensembl=ENSMODG00000012607.4|UniProtKB=F6S326 F6S326 PCGF2 PTHR10825:SF31 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP RING FINGER PROTEIN 2 binding#GO:0005488;chromatin binding#GO:0003682 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000014663.4|UniProtKB=A0A5F8GKD9 A0A5F8GKD9 MTA1 PTHR10865:SF5 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS-ASSOCIATED PROTEIN MTA1 protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713;histone deacetylase binding#GO:0042826;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;response to abiotic stimulus#GO:0009628;negative regulation of biological process#GO:0048519;response to ionizing radiation#GO:0010212;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;response to stress#GO:0006950;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;response to radiation#GO:0009314;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;DNA damage response#GO:0006974 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000009324.5|UniProtKB=F7GJN6 F7GJN6 TEX2 PTHR13466:SF2 TEX2 PROTEIN-RELATED TESTIS-EXPRESSED PROTEIN 2 lipid binding#GO:0008289;binding#GO:0005488 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 MONDO|Ensembl=ENSMODG00000012230.2|UniProtKB=F6Z6N8 F6Z6N8 NME5 PTHR46161:SF1 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE 5 transferase#PC00220;nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo purine biosynthesis#P02738>GDP kinase#P02891 MONDO|Ensembl=ENSMODG00000029475.2|UniProtKB=F6SCQ7 F6SCQ7 PRSS50 PTHR24256:SF246 TRYPTASE-RELATED SERINE PROTEASE 42-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000016928.4|UniProtKB=A0A5F8G4H1 A0A5F8G4H1 SEMA4A PTHR11036:SF15 SEMAPHORIN SEMAPHORIN-4A signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;taxis#GO:0042330;response to chemical#GO:0042221;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;chemotaxis#GO:0006935;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane-bound signaling molecule#PC00152 MONDO|Ensembl=ENSMODG00000004712.4|UniProtKB=A0A5F8H4H6 A0A5F8H4H6 SRGAP3 PTHR14166:SF8 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 3 GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;system development#GO:0048731;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;regulation of locomotion#GO:0040012;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;negative regulation of locomotion#GO:0040013;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of cell migration#GO:0030334;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 GTPase-activating protein#PC00257;G-protein modulator#PC00022 PDGF signaling pathway#P00047>Rho#P01174 MONDO|Ensembl=ENSMODG00000013723.4|UniProtKB=F6XRJ4 F6XRJ4 TBXAS1 PTHR24301:SF17 THROMBOXANE-A SYNTHASE THROMBOXANE-A SYNTHASE intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824 isomerase#PC00135;metabolite interconversion enzyme#PC00262 MONDO|Ensembl=ENSMODG00000022928.1|UniProtKB=F6PZ89 F6PZ89 LOC100020786 PTHR26450:SF116 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000004619.3|UniProtKB=F6XLE6 F6XLE6 MYO1H PTHR13140:SF353 MYOSIN UNCONVENTIONAL MYOSIN-IH macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based movement#GO:0030048;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;transport#GO:0006810;actin filament-based process#GO:0030029;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232 actin binding motor protein#PC00040 MONDO|Ensembl=ENSMODG00000023354.3|UniProtKB=F6QJ81 F6QJ81 PTHR14819:SF5 GTP-BINDING INTERFERON-INDUCED VERY LARGE GTPASE 1 MONDO|Ensembl=ENSMODG00000049706.1|UniProtKB=A0A5F8G583 A0A5F8G583 PTHR24230:SF17 G-PROTEIN COUPLED RECEPTOR GALANIN RECEPTOR TYPE 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000049220.1|UniProtKB=A0A5F8H9D5 A0A5F8H9D5 LOC130454707 PTHR48001:SF105 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000038786.1|UniProtKB=A0A5F8HBM4 A0A5F8HBM4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000003237.4|UniProtKB=F6THW6 F6THW6 SMYD2 PTHR12197:SF193 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD N-LYSINE METHYLTRANSFERASE SMYD2 transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;histone H3K36 methyltransferase activity#GO:0046975;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;lysine N-methyltransferase activity#GO:0016278 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;heart development#GO:0007507;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;circulatory system development#GO:0072359;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 MONDO|Ensembl=ENSMODG00000008241.4|UniProtKB=K7E500 K7E500 L3HYPDH PTHR33442:SF1 TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 MONDO|Ensembl=ENSMODG00000045912.1|UniProtKB=A0A5F8G8I8 A0A5F8G8I8 PTHR41694:SF8 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 11 POL PROTEIN-LIKE nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000023126.2|UniProtKB=F6YXW0 F6YXW0 SERTAD2 PTHR16277:SF10 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 SERTA DOMAIN-CONTAINING PROTEIN 2 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 transcription cofactor#PC00217 MONDO|Ensembl=ENSMODG00000007561.3|UniProtKB=F7FZZ9 F7FZZ9 PIP4P2 PTHR21014:SF5 PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE TYPE 2 PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 4-PHOSPHATASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;dephosphorylation#GO:0016311;lipid modification#GO:0030258;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;late endosome membrane#GO:0031902;late endosome#GO:0005770;phagocytic vesicle#GO:0045335;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 MONDO|Ensembl=ENSMODG00000016585.4|UniProtKB=H9H702 H9H702 PTHR22957:SF598 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 26 GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 MONDO|Ensembl=ENSMODG00000002182.4|UniProtKB=F7GEC2 F7GEC2 ELAPOR1 PTHR22727:SF13 PROTEIN CBG13728 ENDOSOME_LYSOSOME-ASSOCIATED APOPTOSIS AND AUTOPHAGY REGULATOR 1 regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;positive regulation of organelle organization#GO:0010638;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925;positive regulation of cellular component organization#GO:0051130;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;biological regulation#GO:0065007;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152 Golgi apparatus#GO:0005794;lytic vacuole#GO:0000323;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;plasma membrane#GO:0005886;vacuole#GO:0005773;endomembrane system#GO:0012505;late endosome#GO:0005770;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 MONDO|Ensembl=ENSMODG00000025385.1|UniProtKB=F6YJM4 F6YJM4 PTHR26452:SF247 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5K3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;system process#GO:0003008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000043698.1|UniProtKB=A0A5F8GAZ7 A0A5F8GAZ7 CCDC166 PTHR14845:SF4 COILED-COIL DOMAIN-CONTAINING 166 COILED-COIL DOMAIN-CONTAINING PROTEIN 166 MONDO|Ensembl=ENSMODG00000015849.4|UniProtKB=F7F0F0 F7F0F0 UNC80 PTHR31781:SF1 UNC80 PROTEIN UNC-80 HOMOLOG monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 monoatomic ion transmembrane transport#GO:0034220;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;regulation of system process#GO:0044057;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;metal ion transport#GO:0030001;homeostatic process#GO:0042592;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811 neuron projection#GO:0043005;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;axon#GO:0030424;cation channel complex#GO:0034703;sodium channel complex#GO:0034706;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 MONDO|Ensembl=ENSMODG00000039726.1|UniProtKB=A0A5F8GE24 A0A5F8GE24 LOC100024463 PTHR26453:SF45 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000003354.3|UniProtKB=F6ZPY7 F6ZPY7 OMA1 PTHR22726:SF1 METALLOENDOPEPTIDASE OMA1 METALLOENDOPEPTIDASE OMA1, MITOCHONDRIAL catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 MONDO|Ensembl=ENSMODG00000020877.5|UniProtKB=H9H7P4 H9H7P4 NOL8 PTHR48029:SF10 NUCLEOLAR PROTEIN 8 NUCLEOLAR PROTEIN 8 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 MONDO|Ensembl=ENSMODG00000047855.1|UniProtKB=F7GHX4 F7GHX4 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000049391.1|UniProtKB=A0A5F8H6S8 A0A5F8H6S8 OR10J1 PTHR26451:SF344 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10J1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 MONDO|Ensembl=ENSMODG00000000956.4|UniProtKB=F6UUB2 F6UUB2 WIPI2 PTHR11227:SF27 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 2 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;ion binding#GO:0043167 carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;polysaccharide catabolic process#GO:0000272;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;localization#GO:0051179;vacuole organization#GO:0007033;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;energy derivation by oxidation of organic compounds#GO:0015980;pexophagy#GO:0000425;macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091;macroautophagy#GO:0016236;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;phagophore assembly site#GO:0000407;membrane#GO:0016020 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000004821.4|UniProtKB=A0A5F8GWD2 A0A5F8GWD2 LOC103101763 PTHR42985:SF10 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 1 symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804 lipid localization#GO:0010876;monoatomic cation transport#GO:0006812;localization#GO:0051179;fatty acid transport#GO:0015908;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;monocarboxylic acid transport#GO:0015718;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 MONDO|Ensembl=ENSMODG00000039943.1|UniProtKB=F6PZN6 F6PZN6 LOC100021854 PTHR26450:SF67 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51V1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000029566.2|UniProtKB=K7DYS0 K7DYS0 PTHR11505:SF218 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000050790.1|UniProtKB=A0A5F8H4E3 A0A5F8H4E3 PTHR46890:SF56 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED OS06G0484800 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000008553.5|UniProtKB=A0A5F8GVG2 A0A5F8GVG2 MAP3K21 PTHR44329:SF30 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 21 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 MONDO|Ensembl=ENSMODG00000018186.4|UniProtKB=F7BTJ8 F7BTJ8 IGSF11 PTHR44699:SF1 IMMUNOGLOBULIN SUPERFAMILY MEMBER 11 IMMUNOGLOBULIN SUPERFAMILY MEMBER 11 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 immunoglobulin#PC00123 MONDO|Ensembl=ENSMODG00000020983.3|UniProtKB=F6S556 F6S556 VPS26C PTHR12233:SF2 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26C establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 MONDO|Ensembl=ENSMODG00000045335.1|UniProtKB=A0A5F8GC92 A0A5F8GC92 PTHR10464:SF6 UREA TRANSPORTER UREA TRANSPORTER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810;nitrogen compound transport#GO:0071705 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 MONDO|Ensembl=ENSMODG00000049373.1|UniProtKB=A0A5F8HGT6 A0A5F8HGT6 PTHR25952:SF252 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000004650.4|UniProtKB=F6UN90 F6UN90 EDA PTHR15151:SF13 PROTEIN EIGER ECTODYSPLASIN-A cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 anatomical structure morphogenesis#GO:0009653;immune response#GO:0006955;odontogenesis of dentin-containing tooth#GO:0042475;response to stimulus#GO:0050896;animal organ morphogenesis#GO:0009887;odontogenesis#GO:0042476;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;animal organ development#GO:0048513;anatomical structure development#GO:0048856 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 MONDO|Ensembl=ENSMODG00000009651.4|UniProtKB=A0A5F8H5F0 A0A5F8H5F0 LIMK2 PTHR46485:SF1 LIM DOMAIN KINASE 1 LIM DOMAIN KINASE 2 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000025492.2|UniProtKB=A0A5F8GKB3 A0A5F8GKB3 PTHR23024:SF239 ARYLACETAMIDE DEACETYLASE AADACL2 FAMILY MEMBER 2 membrane#GO:0016020;cellular anatomical structure#GO:0110165 deacetylase#PC00087 MONDO|Ensembl=ENSMODG00000027720.2|UniProtKB=K7E2H5 K7E2H5 PTHR19446:SF435 REVERSE TRANSCRIPTASES LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000004620.4|UniProtKB=A0A5F8GDR9 A0A5F8GDR9 ACSL1 PTHR43272:SF116 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 1 ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;long-chain fatty acid metabolic process#GO:0001676;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 ligase#PC00142 MONDO|Ensembl=ENSMODG00000015964.4|UniProtKB=F7FDE1 F7FDE1 GNL1 PTHR45709:SF3 LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 MONDO|Ensembl=ENSMODG00000004669.4|UniProtKB=F6VG61 F6VG61 PDLIM7 PTHR24214:SF0 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 7 protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;circulatory system development#GO:0072359;cellular component organization#GO:0016043;system development#GO:0048731;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;heart development#GO:0007507;cellular process#GO:0009987;organelle organization#GO:0006996;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502 myofibril#GO:0030016;actin filament bundle#GO:0032432;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cell junction#GO:0030054;adherens junction#GO:0005912;stress fiber#GO:0001725;cytoskeleton#GO:0005856;actin filament#GO:0005884;I band#GO:0031674;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell-cell junction#GO:0005911;Z disc#GO:0030018;actomyosin#GO:0042641;contractile muscle fiber#GO:0043292 actin or actin-binding cytoskeletal protein#PC00041 MONDO|Ensembl=ENSMODG00000013817.4|UniProtKB=F6SEY5 F6SEY5 PPFIA3 PTHR12587:SF4 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA-3 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 presynapse#GO:0098793;presynaptic active zone#GO:0048786;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000002653.3|UniProtKB=A0A5F8H5V6 A0A5F8H5V6 RCC2 PTHR46207:SF1 PROTEIN RCC2 PROTEIN RCC2 enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515;small GTPase binding#GO:0031267 regulation of chromosome segregation#GO:0051983;localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to kinetochore#GO:0034501;positive regulation of cell cycle process#GO:0090068;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;positive regulation of cell cycle#GO:0045787 membrane#GO:0016020;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000000345.4|UniProtKB=A0ACM8QM25 A0ACM8QM25 MILL-like PTHR16675:SF242 MHC CLASS I-RELATED MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I-RELATED PROTEIN 1 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000011636.4|UniProtKB=F6TJT9 F6TJT9 GTF2A2 PTHR10966:SF0 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 transcription factor binding#GO:0008134;binding#GO:0005488;protein binding#GO:0005515 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233 general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 MONDO|Ensembl=ENSMODG00000001128.3|UniProtKB=F7D520 F7D520 PPIF PTHR11071:SF408 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE F, MITOCHONDRIAL response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;response to reactive oxygen species#GO:0000302;response to chemical#GO:0042221;regulation of membrane permeability#GO:0090559;cellular response to oxidative stress#GO:0034599;regulation of mitochondrial membrane permeability#GO:0046902;biological regulation#GO:0065007;response to stress#GO:0006950;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;regulation of biological quality#GO:0065008;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane#GO:0016020;mitochondrion#GO:0005739;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000029345.2|UniProtKB=K7E2S9 K7E2S9 PTHR36489:SF1 PROTEIN-COUPLED RECEPTOR GPR1, PUTATIVE-RELATED SEA DOMAIN-CONTAINING PROTEIN G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000005608.4|UniProtKB=F7CZT6 F7CZT6 GPATCH2L PTHR14195:SF3 G PATCH DOMAIN CONTAINING PROTEIN 2 G PATCH DOMAIN-CONTAINING PROTEIN 2-LIKE intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 MONDO|Ensembl=ENSMODG00000016897.4|UniProtKB=A0A5F8HHC3 A0A5F8HHC3 PTHR14463:SF10 LIPASE MATURATION FACTOR LIPASE MATURATION FACTOR 1 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000020815.4|UniProtKB=F6RN27 F6RN27 KLK14 PTHR24271:SF48 KALLIKREIN-RELATED KALLIKREIN-14 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;extracellular region#GO:0005576;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982 serine protease#PC00203 MONDO|Ensembl=ENSMODG00000007649.4|UniProtKB=F7FZH1 F7FZH1 C19orf47 PTHR21359:SF1 DUF5577 DOMAIN-CONTAINING PROTEIN DUF5577 DOMAIN-CONTAINING PROTEIN MONDO|Ensembl=ENSMODG00000023640.3|UniProtKB=F7ECR7 F7ECR7 LOC100617593 PTHR24376:SF38 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 544-RELATED gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000015112.4|UniProtKB=A0A5F8H8Q9 A0A5F8H8Q9 CCDC50 PTHR22115:SF1 C3ORF6 PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 50 protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 MONDO|Ensembl=ENSMODG00000045663.1|UniProtKB=A0A5F8G690 A0A5F8G690 PTHR47958:SF90 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX5-RELATED ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA helicase#PC00032 MONDO|Ensembl=ENSMODG00000042918.1|UniProtKB=A0A5F8G5F8 A0A5F8G5F8 ARL16 PTHR46688:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16 MONDO|Ensembl=ENSMODG00000002386.4|UniProtKB=A0A5F8GKW8 A0A5F8GKW8 PTHR33560:SF2 PROTEIN FAM227B PROTEIN FAM227B MONDO|Ensembl=ENSMODG00000014401.3|UniProtKB=F7C283 F7C283 PIH1D2 PTHR22997:SF6 PIH1 DOMAIN-CONTAINING PROTEIN 1 PIH1 DOMAIN-CONTAINING PROTEIN 2 cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 MONDO|Ensembl=ENSMODG00000016801.4|UniProtKB=F7FVK2 F7FVK2 CRABP2 PTHR11955:SF152 FATTY ACID BINDING PROTEIN CELLULAR RETINOIC ACID-BINDING PROTEIN 2 ion binding#GO:0043167;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;binding#GO:0005488;anion binding#GO:0043168;organic acid binding#GO:0043177;fatty acid binding#GO:0005504;lipid binding#GO:0008289 lipid localization#GO:0010876;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;fatty acid transport#GO:0015908;localization#GO:0051179;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;lipid transport#GO:0006869 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 MONDO|Ensembl=ENSMODG00000004095.3|UniProtKB=F6VVN3 F6VVN3 RPS6 PTHR11502:SF6 40S RIBOSOMAL PROTEIN S6 SMALL RIBOSOMAL SUBUNIT PROTEIN ES6 ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000005602.4|UniProtKB=F7DJ64 F7DJ64 SLC6A11 PTHR11616:SF124 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 3 transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370 sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;amino acid transport#GO:0006865;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 MONDO|Ensembl=ENSMODG00000046989.1|UniProtKB=A0A5F8G8F2 A0A5F8G8F2 SLC35F6 PTHR13146:SF0 SOLUTE CARRIER FAMILY 35 MEMBER F6-RELATED SOLUTE CARRIER FAMILY 35 MEMBER F6 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000021213.4|UniProtKB=F6UGK4 F6UGK4 TM4SF20 PTHR14198:SF17 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 20 cellular anatomical structure#GO:0110165;membrane#GO:0016020 MONDO|Ensembl=ENSMODG00000046779.1|UniProtKB=A0A5F8GX22 A0A5F8GX22 PTHR10902:SF0 60S RIBOSOMAL PROTEIN L35A LARGE RIBOSOMAL SUBUNIT PROTEIN EL33 translational protein#PC00263;ribosomal protein#PC00202 MONDO|Ensembl=ENSMODG00000010707.4|UniProtKB=A0A5F8HK45 A0A5F8HK45 SLC52A2 PTHR12929:SF1 SOLUTE CARRIER FAMILY 52 SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 nitrogen compound transport#GO:0071705;transport#GO:0006810;vitamin transport#GO:0051180;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 MONDO|Ensembl=ENSMODG00000016286.4|UniProtKB=F7AU60 F7AU60 OTOL1 PTHR15427:SF51 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER OTOLIN 1 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;lipid modification#GO:0030258 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 MONDO|Ensembl=ENSMODG00000009927.3|UniProtKB=F7F2R1 F7F2R1 PTHR33426:SF29 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED MONDO|Ensembl=ENSMODG00000016762.3|UniProtKB=F7GGL8 F7GGL8 ADAMDEC1 PTHR11905:SF125 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM DEC1 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 MONDO|Ensembl=ENSMODG00000019624.4|UniProtKB=F6XPY0 F6XPY0 LOC100032364 PTHR11575:SF48 5'-NUCLEOTIDASE-RELATED ECTO-5'-NUCLEOTIDASE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 MONDO|Ensembl=ENSMODG00000018461.3|UniProtKB=F7CAX1 F7CAX1 LOC100619417 PTHR26453:SF293 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000001918.4|UniProtKB=F6W119 F6W119 ATPAF1 PTHR13126:SF0 CHAPERONE ATP11 ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1 mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 MONDO|Ensembl=ENSMODG00000010418.4|UniProtKB=F7A6V0 F7A6V0 MTFMT PTHR11138:SF5 METHIONYL-TRNA FORMYLTRANSFERASE METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 RNA metabolism protein#PC00031;RNA processing factor#PC00147 MONDO|Ensembl=ENSMODG00000006095.5|UniProtKB=F7F126 F7F126 ITPKB PTHR12400:SF4 INOSITOL POLYPHOSPHATE KINASE INOSITOL-TRISPHOSPHATE 3-KINASE B phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase#PC00137 MONDO|Ensembl=ENSMODG00000015373.4|UniProtKB=F6WH53 F6WH53 JAK2 PTHR45807:SF1 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE JAK2 cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;non-membrane spanning protein tyrosine kinase activity#GO:0004715;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 hemopoiesis#GO:0030097;response to other organism#GO:0051707;cellular response to nitrogen compound#GO:1901699;developmental process#GO:0032502;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;response to external stimulus#GO:0009605;cellular developmental process#GO:0048869;homeostatic process#GO:0042592;response to external biotic stimulus#GO:0043207;cellular response to peptide hormone stimulus#GO:0071375;homeostasis of number of cells#GO:0048872;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;erythrocyte differentiation#GO:0030218;enzyme-linked receptor protein signaling pathway#GO:0007167;tumor necrosis factor-mediated signaling pathway#GO:0033209;response to stress#GO:0006950;response to hormone#GO:0009725;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;response to endogenous stimulus#GO:0009719;regulation of programmed cell death#GO:0043067;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;response to peptide#GO:1901652;immune response#GO:0006955;response to tumor necrosis factor#GO:0034612;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;multicellular organismal process#GO:0032501;multicellular organismal-level homeostasis#GO:0048871;defense response#GO:0006952;innate immune response#GO:0045087;cellular response to stimulus#GO:0051716;cellular response to chemokine#GO:1990869;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cytokine-mediated signaling pathway#GO:0019221;chemokine-mediated signaling pathway#GO:0070098;anatomical structure development#GO:0048856;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to type II interferon#GO:0034341;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to chemokine#GO:1990868;cell surface receptor signaling pathway via STAT#GO:0097696;defense response to other organism#GO:0098542;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cell development#GO:0048468;response to stimulus#GO:0050896;myeloid cell differentiation#GO:0030099;cellular response to hormone stimulus#GO:0032870;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 non-receptor tyrosine protein kinase#PC00168 PDGF signaling pathway#P00047>Jak#P01155;PI3 kinase pathway#P00048>JAK#P01176;CCKR signaling map#P06959>JAK2#P07156;Interferon-gamma signaling pathway#P00035>Jak2#P00952;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>JAK#P00846;JAK/STAT signaling pathway#P00038>Jak#P01034 MONDO|Ensembl=ENSMODG00000048882.1|UniProtKB=A0A5F8H8I8 A0A5F8H8I8 ITIH1 PTHR10338:SF106 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H1 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 MONDO|Ensembl=ENSMODG00000006915.4|UniProtKB=F6PSD1 F6PSD1 GRIN2C PTHR18966:SF361 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2C dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of synaptic transmission#GO:0050806;nervous system process#GO:0050877;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of biological quality#GO:0065008;synaptic signaling#GO:0099536;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell surface receptor signaling pathway#GO:0007166;regulation of membrane potential#GO:0042391;chemical synaptic transmission#GO:0007268;regulation of postsynaptic membrane potential#GO:0060078;cellular response to stimulus#GO:0051716;anterograde trans-synaptic signaling#GO:0098916;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;chemical synaptic transmission, postsynaptic#GO:0099565;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of synaptic plasticity#GO:0048167;system process#GO:0003008 synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>NR2C#P01006;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039 MONDO|Ensembl=ENSMODG00000040134.1|UniProtKB=F6Q2G1 F6Q2G1 LOC100024076 PTHR26450:SF170 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E8 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 MONDO|Ensembl=ENSMODG00000012276.3|UniProtKB=F6YG55 F6YG55 SNF8 PTHR12806:SF0 EAP30 SUBUNIT OF ELL COMPLEX VACUOLAR-SORTING PROTEIN SNF8 macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;macromolecule localization#GO:0033036;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;protein metabolic process#GO:0019538;protein localization to vacuole#GO:0072665;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;endosomal transport#GO:0016197;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular localization#GO:0051641;protein transport#GO:0015031;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;establishment of protein localization to vacuole#GO:0072666;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328 cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229 MONDO|Ensembl=ENSMODG00000014198.3|UniProtKB=F6TRC3 F6TRC3 CLN8 PTHR13439:SF7 CT120 PROTEIN PROTEIN CLN8 lipid binding#GO:0008289;binding#GO:0005488 phospholipid metabolic process#GO:0006644;homeostatic process#GO:0042592;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;multicellular organism development#GO:0007275;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;developmental process#GO:0032502 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220 MONDO|Ensembl=ENSMODG00000002856.4|UniProtKB=A0A5F8G3S1 A0A5F8G3S1 ZNF341 PTHR24388:SF28 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 341 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 MONDO|Ensembl=ENSMODG00000028226.2|UniProtKB=K7E102 K7E102 PTHR41694:SF8 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 11 POL PROTEIN-LIKE binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 viral or transposable element protein#PC00237 MONDO|Ensembl=ENSMODG00000006168.4|UniProtKB=F7B5K9 F7B5K9 YLPM1 PTHR13413:SF0 YLP MOTIF CONTAINING PROTEIN NUCLEAR PROTEIN ZAP YLP MOTIF-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of DNA metabolic process#GO:0051052;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of chromosome organization#GO:0033044;regulation of telomere maintenance#GO:0032204 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 MONDO|Ensembl=ENSMODG00000042847.1|UniProtKB=A0A5F8H494 A0A5F8H494 PTHR23262:SF186 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 1-1 structural protein#PC00211 MONDO|Ensembl=ENSMODG00000017414.3|UniProtKB=A0A5F8HE79 A0A5F8HE79 PERP PTHR14399:SF4 P53-INDUCED PROTEIN RELATED P53 APOPTOSIS EFFECTOR RELATED TO PMP-22 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 p53 pathway#P00059>PERP#G01565 MONDO|Ensembl=ENSMODG00000038653.1|UniProtKB=A0A5F8G8I5 A0A5F8G8I5 PTHR16675:SF67 MHC CLASS I-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000014200.4|UniProtKB=A0A5F8H5F2 A0A5F8H5F2 PTHR23333:SF4 UBX DOMAIN CONTAINING PROTEIN UBX DOMAIN-CONTAINING PROTEIN 11 binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 protein-binding activity modulator#PC00095 MONDO|Ensembl=ENSMODG00000039514.1|UniProtKB=A0A5F8G9W3 A0A5F8G9W3 PDP1 PTHR13832:SF627 PROTEIN PHOSPHATASE 2C [PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 1, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein phosphatase#PC00195 MONDO|Ensembl=ENSMODG00000036906.1|UniProtKB=A0A5F8G6W4 A0A5F8G6W4 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 MONDO|Ensembl=ENSMODG00000006228.4|UniProtKB=F7C7M8 F7C7M8 HSF4 PTHR10015:SF213 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 4 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 MONDO|Ensembl=ENSMODG00000004727.4|UniProtKB=F6Y272 F6Y272 UFSP2 PTHR48153:SF6 UFM1-SPECIFIC PROTEASE 2 UFM1-SPECIFIC PROTEASE 2 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622